locus-tag	class	description
A2cp1_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
A2cp1_0005	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A2cp1_0008	ENOG4105DF6	Fe-S oxidoreductase
A2cp1_0011	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A2cp1_0012	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
A2cp1_0013	ENOG4107TEJ	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
A2cp1_0014	ENOG4107XN1	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
A2cp1_0019	ENOG4105MN3	Resolvase
A2cp1_0036	ENOG4105CUX	Signal transduction histidine kinase
A2cp1_0039	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
A2cp1_0045	ENOG4105C8Q	Methyl-accepting chemotaxis
A2cp1_0046	ENOG4105DTD	Dehydrogenase
A2cp1_0049	ENOG4105CK7	Sodium proline symporter
A2cp1_0052	ENOG4105DZS	Phenylacetate-CoA ligase
A2cp1_0054	ENOG4105DZS	Phenylacetate-CoA ligase
A2cp1_0057	ENOG4107RE7	phosphate butyryltransferase
A2cp1_0058	ENOG4105CKM	Branched-chain carboxylic acid kinase
A2cp1_0064	ENOG4105BZJ	Electron transfer flavoprotein
A2cp1_0065	ENOG4105C10	Electron transfer flavoprotein
A2cp1_0066	ENOG4105C5X	domain protein
A2cp1_0067	ENOG4105EE5	Membrane protein terC
A2cp1_0072	ENOG4107T0X	DNA ligase
A2cp1_0073	ENOG4105C34	Pseudouridine synthase
A2cp1_0074	ENOG4108JQC	penicillin-binding protein 1A
A2cp1_0075	ENOG4107SDU	Methyl-accepting chemotaxis
A2cp1_0077	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
A2cp1_0078	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
A2cp1_0080	ENOG4105CHU	acetyl-coa acetyltransferase
A2cp1_0084	ENOG4105CCT	upf0313 protein
A2cp1_0087	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
A2cp1_0091	ENOG4105C0H	protease
A2cp1_0093	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
A2cp1_0094	ENOG4108Z86	Glutamine amidotransferase
A2cp1_0095	ENOG4105DWF	phosphomethylpyrimidine kinase
A2cp1_0097	ENOG4105CDU	Replicative dna helicase
A2cp1_0099	ENOG41067MG	lrgb family
A2cp1_0100	ENOG4105VAW	lrga family
A2cp1_0101	ENOG4105DND	Transcriptional regulator
A2cp1_0102	ENOG4105C3R	Methionine synthase
A2cp1_0107	ENOG4105D7A	ATP-binding protein
A2cp1_0108	ENOG4105BZU	Histidine kinase
A2cp1_0116	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
A2cp1_0117	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A2cp1_0119	ENOG4105BZU	Histidine kinase
A2cp1_0120	ENOG4107RAN	Peptidase, M16
A2cp1_0124	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_0125	ENOG4105BZU	Histidine kinase
A2cp1_0130	ENOG4105DFF	Rod shape-determining protein mreb
A2cp1_0131	ENOG4105DFF	Rod shape-determining protein mreb
A2cp1_0132	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
A2cp1_0133	ENOG4105D9P	serine threonine protein kinase
A2cp1_0136	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
A2cp1_0139	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
A2cp1_0144	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
A2cp1_0145	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
A2cp1_0150	ENOG4105BZU	Histidine kinase
A2cp1_0157	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
A2cp1_0159	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
A2cp1_0162	ENOG410812K	response regulator receiver protein
A2cp1_0164	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
A2cp1_0166	ENOG4108EQA	pts system
A2cp1_0169	ENOG4105F3R	pts system mannose fructose sorbose family iid
A2cp1_0170	ENOG41080Z8	PHOSPHOCARRIER protein
A2cp1_0174	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
A2cp1_0177	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
A2cp1_0179	ENOG4105E2R	ROK family
A2cp1_0191	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
A2cp1_0195	ENOG4105BZU	Histidine kinase
A2cp1_0199	ENOG4105F4X	arginine
A2cp1_0200	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
A2cp1_0201	ENOG4107YU2	histidine triad (hIT) protein
A2cp1_0204	ENOG4105KHN	chorismate mutase
A2cp1_0210	ENOG4105D49	3-dehydroquinate synthase
A2cp1_0211	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
A2cp1_0213	ENOG4108UQY	Iron-storage protein
A2cp1_0218	ENOG4105C34	Pseudouridine synthase
A2cp1_0224	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
A2cp1_0230	ENOG4107RGD	Major Facilitator superfamily
A2cp1_0235	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
A2cp1_0239	ENOG4108Q5Y	Membrane
A2cp1_0241	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
A2cp1_0256	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
A2cp1_0257	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
A2cp1_0262	ENOG4105HP8	regulator of competence-specific genes
A2cp1_0263	ENOG4105CSA	Coproporphyrinogen iii oxidase
A2cp1_0265	ENOG4105EPD	Oligopeptide transporter, Opt family
A2cp1_0266	ENOG4108RQS	Two component transcriptional regulator (Winged helix family
A2cp1_0267	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A2cp1_0268	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
A2cp1_0271	ENOG4107QX3	carboxylase
A2cp1_0273	ENOG4105VEQ	Cold shock protein
A2cp1_0274	ENOG4107QWG	2-Nitropropane dioxygenase
A2cp1_0276	ENOG4106HNH	Acyl-transferase
A2cp1_0278	ENOG4105BZU	Histidine kinase
A2cp1_0279	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A2cp1_0280	ENOG4107QSA	Oxaloacetate decarboxylase
A2cp1_0282	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A2cp1_0287	ENOG4105C34	Pseudouridine synthase
A2cp1_0288	ENOG4108ZZF	transport protein (ExbD)
A2cp1_0289	ENOG4105SG9	biopolymer transport protein, ExbD
A2cp1_0290	ENOG4105E02	MotA TolQ exbB proton channel
A2cp1_0292	ENOG4108KPZ	tonB-dependent Receptor
A2cp1_0295	ENOG4105CE9	30S ribosomal protein S2
A2cp1_0298	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
A2cp1_0299	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
A2cp1_0300	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
A2cp1_0301	ENOG4105DJ0	Poly(A) Polymerase
A2cp1_0302	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
A2cp1_0313	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A2cp1_0314	ENOG410902C	phosphohistidine phosphatase, SixA
A2cp1_0316	ENOG4107S1W	4-alpha-glucanotransferase
A2cp1_0317	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
A2cp1_0321	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
A2cp1_0323	ENOG4105BZU	Histidine kinase
A2cp1_0325	ENOG4105SXS	Protein of unknown function (DUF456)
A2cp1_0332	ENOG4105VSH	4-oxalocrotonate tautomerase
A2cp1_0333	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
A2cp1_0334	ENOG4105C5Q	Transcriptional regulator
A2cp1_0344	ENOG4107G87	m6 family metalloprotease domain protein
A2cp1_0347	ENOG4105CD8	aminopeptidase N
A2cp1_0348	ENOG4105E0X	reductase
A2cp1_0351	ENOG4105VG1	fes assembly suf system protein
A2cp1_0355	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
A2cp1_0363	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
A2cp1_0369	ENOG4105C8Q	Methyl-accepting chemotaxis
A2cp1_0372	ENOG4105ETT	transcriptional Regulator, LysR family
A2cp1_0376	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
A2cp1_0378	ENOG4105HMI	Membrane
A2cp1_0379	ENOG4105DUM	transcriptional regulator, lysR family
A2cp1_0380	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
A2cp1_0383	ENOG4108KPJ	rna polymerase sigma factor
A2cp1_0385	ENOG4105CB5	ATP-dependent DNA helicase recG
A2cp1_0387	ENOG4108JU7	Transcriptional regulator
A2cp1_0389	ENOG4105CHU	acetyl-coa acetyltransferase
A2cp1_0390	ENOG4105C1G	acyl-Coa dehydrogenase
A2cp1_0395	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
A2cp1_0399	ENOG4107Y3Y	amidohydrolase
A2cp1_0400	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
A2cp1_0401	ENOG4105DVY	radical SAM domain protein
A2cp1_0402	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
A2cp1_0403	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A2cp1_0404	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
A2cp1_0406	ENOG4105C1V	Peptidase, M16
A2cp1_0410	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A2cp1_0411	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
A2cp1_0414	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A2cp1_0415	ENOG4105C0H	protease
A2cp1_0418	ENOG4107RCI	amp-dependent synthetase and ligase
A2cp1_0419	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
A2cp1_0420	ENOG4106B0W	Curli production assembly transport component CsgG
A2cp1_0426	ENOG4105DGW	oligopeptidase A
A2cp1_0430	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A2cp1_0433	ENOG4105CJ1	ABC, transporter
A2cp1_0436	ENOG4105CHU	acetyl-coa acetyltransferase
A2cp1_0437	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A2cp1_0439	ENOG4105BZU	Histidine kinase
A2cp1_0440	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A2cp1_0441	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
A2cp1_0442	ENOG4105D65	subunit l
A2cp1_0443	ENOG4105C8S	subunit m
A2cp1_0447	ENOG4105BZU	Histidine kinase
A2cp1_0448	ENOG4105EM7	Selenocysteine-specific translation elongation factor
A2cp1_0449	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
A2cp1_0450	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
A2cp1_0452	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A2cp1_0453	ENOG4105PSQ	Acyl-transferase
A2cp1_0455	ENOG41067TZ	transcriptional regulator, MarR family
A2cp1_0458	ENOG4105BZU	Histidine kinase
A2cp1_0461	ENOG41065RQ	ADP-ribosylation crystallin J1
A2cp1_0462	ENOG4105EYH	Exonuclease
A2cp1_0463	ENOG4107RH8	nuclease SbcCD subunit D
A2cp1_0470	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A2cp1_0476	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
A2cp1_0478	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
A2cp1_0480	ENOG4105CPC	Aldo Keto reductase
A2cp1_0484	ENOG4105D5T	phosphonate abc transporter
A2cp1_0485	ENOG4105S7S	phosphonate abc transporter
A2cp1_0486	ENOG4107T9Q	phosphonate abc transporter
A2cp1_0492	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A2cp1_0496	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
A2cp1_0497	ENOG4105QUH	Domain of unknown function (DUF2088)
A2cp1_0503	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
A2cp1_0506	ENOG4105DPX	Hydrogenase, large subunit
A2cp1_0507	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
A2cp1_0508	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
A2cp1_0509	ENOG4105E3S	small subunit
A2cp1_0515	ENOG4105KT7	mgtC SapB transporter
A2cp1_0521	ENOG4108JJB	ABC transporter
A2cp1_0523	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
A2cp1_0526	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
A2cp1_0532	ENOG4108TQ9	Histidine kinase
A2cp1_0533	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_0535	ENOG4105ES5	Histidine kinase
A2cp1_0536	ENOG4105CVN	desaturase
A2cp1_0537	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
A2cp1_0539	ENOG4105NXH	GreA GreB family elongation factor
A2cp1_0543	ENOG4105DU1	integral membrane protein, terc
A2cp1_0545	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
A2cp1_0546	ENOG4105BZS	acriflavin resistance protein
A2cp1_0547	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
A2cp1_0548	ENOG4108Q5F	Tetr family transcriptional regulator
A2cp1_0549	ENOG4105CG3	alpha amylase, catalytic region
A2cp1_0551	ENOG4105D74	hydrolase
A2cp1_0553	ENOG4105WD1	Membrane
A2cp1_0559	ENOG4108WIQ	phosphoesterase PA-phosphatase related protein
A2cp1_0560	ENOG4108SKZ	Patatin-like phospholipase
A2cp1_0562	ENOG4105CHM	Aminotransferase
A2cp1_0565	ENOG4105BZU	Histidine kinase
A2cp1_0567	ENOG4108JJB	ABC transporter
A2cp1_0568	ENOG4105VKD	bioY protein
A2cp1_0569	ENOG4105FBA	Phospholipase Carboxylesterase
A2cp1_0578	ENOG4108JSS	Haloalkane dehalogenase
A2cp1_0579	ENOG4105EJC	lysr family transcriptional regulator
A2cp1_0581	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
A2cp1_0586	ENOG4105EMN	RNA polymerase sigma factor
A2cp1_0592	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
A2cp1_0593	ENOG4107R3N	Filamentation induced by cAMP protein fic
A2cp1_0594	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
A2cp1_0595	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A2cp1_0596	ENOG4105CI2	imidazolone-5-propionate hydrolase
A2cp1_0597	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
A2cp1_0600	ENOG4105JAB	phenazine biosynthesis protein, phzf family
A2cp1_0603	ENOG4105C1V	Peptidase, M16
A2cp1_0604	ENOG4105BZU	Histidine kinase
A2cp1_0610	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
A2cp1_0614	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
A2cp1_0615	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
A2cp1_0617	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
A2cp1_0619	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
A2cp1_0620	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
A2cp1_0621	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
A2cp1_0622	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
A2cp1_0624	ENOG4105WVQ	Fe-S assembly protein IscX
A2cp1_0625	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A2cp1_0626	ENOG4105BZU	Histidine kinase
A2cp1_0627	ENOG4108V3W	Chemotaxis protein, CheW
A2cp1_0628	ENOG4105CBS	Chea signal transduction histidine kinase
A2cp1_0629	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
A2cp1_0631	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
A2cp1_0634	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
A2cp1_0637	ENOG4108QAF	Methyl-accepting chemotaxis sensory transducer
A2cp1_0638	ENOG4105CBS	Chea signal transduction histidine kinase
A2cp1_0639	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A2cp1_0640	ENOG4105BZU	Histidine kinase
A2cp1_0641	ENOG4108UXN	response regulator
A2cp1_0646	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A2cp1_0651	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
A2cp1_0652	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
A2cp1_0654	ENOG4105KG3	cytidine deaminase
A2cp1_0655	ENOG4105DTN	riboflavin biosynthesis protein ribF
A2cp1_0656	ENOG4107QHF	type ii secretion system protein e
A2cp1_0657	ENOG4105CZX	twitching motility protein
A2cp1_0659	ENOG4105BZU	Histidine kinase
A2cp1_0660	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_0669	ENOG4106855	Competence protein
A2cp1_0671	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
A2cp1_0673	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_0675	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
A2cp1_0679	ENOG4105E4G	Type IV pilus
A2cp1_0682	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
A2cp1_0683	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
A2cp1_0684	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
A2cp1_0689	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A2cp1_0690	ENOG4105C59	p-type ATPase
A2cp1_0696	ENOG4105M8F	Biopolymer transport protein exbD tolR
A2cp1_0697	ENOG4105E02	MotA TolQ exbB proton channel
A2cp1_0699	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
A2cp1_0701	ENOG4105CAK	Cell division ATP-binding protein ftsE
A2cp1_0702	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
A2cp1_0703	ENOG41063SB	peptidase
A2cp1_0704	ENOG4105CN1	protease
A2cp1_0707	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A2cp1_0708	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
A2cp1_0709	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
A2cp1_0710	ENOG4105C8Q	Methyl-accepting chemotaxis
A2cp1_0715	ENOG4108WWZ	General secretion pathway protein J
A2cp1_0717	ENOG4108VAU	general secretion pathway protein G
A2cp1_0718	ENOG4108VAU	general secretion pathway protein G
A2cp1_0719	ENOG4105D7Q	type ii secretion system
A2cp1_0720	ENOG4107QHF	type ii secretion system protein e
A2cp1_0721	ENOG4105GVR	general secretion pathway protein D
A2cp1_0725	ENOG41082DI	50s ribosomal protein l31
A2cp1_0726	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
A2cp1_0730	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
A2cp1_0732	ENOG4105C03	ribonuclease
A2cp1_0732	ENOG4105C03	ribonuclease
A2cp1_0733	ENOG4107S2Z	UPF0761 membrane protein
A2cp1_0734	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
A2cp1_0736	ENOG4105D00	flagellar biosynthetic protein flhB
A2cp1_0739	ENOG4105CN7	Flagellar biosynthetic protein FliP
A2cp1_0741	ENOG4105DD5	Flagellar motor switch protein
A2cp1_0743	ENOG4108RBT	type iii secretion
A2cp1_0748	ENOG4105WH1	Two component transcriptional regulator luxr family
A2cp1_0749	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
A2cp1_0751	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
A2cp1_0753	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
A2cp1_0757	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
A2cp1_0758	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A2cp1_0760	ENOG4105CVJ	phosphoglycerate mutase
A2cp1_0761	ENOG4106HK8	GPR1 FUN34 yaaH family protein
A2cp1_0762	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
A2cp1_0764	ENOG4105C25	Primosomal protein n'
A2cp1_0767	ENOG4105D1H	recombination factor protein RarA
A2cp1_0768	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
A2cp1_0769	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
A2cp1_0770	ENOG4108ZF3	Phosphatase
A2cp1_0771	ENOG4105DR5	peptidase
A2cp1_0773	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
A2cp1_0778	ENOG4105DTT	CRISPR-associated helicase, cas3
A2cp1_0784	ENOG4105TZK	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
A2cp1_0793	ENOG4108KPJ	rna polymerase sigma factor
A2cp1_0798	ENOG4105F4G	Membrane
A2cp1_0801	ENOG4107T8T	UPF0173 metal-dependent hydrolase
A2cp1_0803	ENOG4105DR5	peptidase
A2cp1_0807	ENOG4108V1U	phospholipid-binding protein
A2cp1_0810	ENOG4105HEE	Binding Domain protein
A2cp1_0811	ENOG4105FR1	rard protein
A2cp1_0812	ENOG4105Q9Y	Universal stress protein
A2cp1_0813	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
A2cp1_0817	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
A2cp1_0820	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
A2cp1_0825	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
A2cp1_0828	ENOG4108KXV	response regulator
A2cp1_0832	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A2cp1_0833	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
A2cp1_0834	ENOG4105C7S	Dehydrogenase
A2cp1_0836	ENOG4105DQE	DNA ligase
A2cp1_0839	ENOG4105CQ7	ATP-dependent helicase
A2cp1_0840	ENOG4105VN1	Heat shock protein
A2cp1_0842	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
A2cp1_0846	ENOG4105EMN	RNA polymerase sigma factor
A2cp1_0848	ENOG4107SFQ	iron-sulfur binding
A2cp1_0861	ENOG4105DIA	mandelate racemase muconate lactonizing
A2cp1_0862	ENOG4105CQB	FAD linked oxidase domain protein
A2cp1_0863	ENOG4108UVJ	appr-1-p processing domain protein
A2cp1_0864	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_0865	ENOG4105CRE	cytochrome C
A2cp1_0868	ENOG4105GN4	DNA ligase
A2cp1_0870	ENOG4105BZ8	glutamate synthase
A2cp1_0873	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A2cp1_0875	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
A2cp1_0878	ENOG4105EEM	helicase
A2cp1_0879	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
A2cp1_0880	ENOG4105C5H	ABC transporter
A2cp1_0881	ENOG4105C26	Dehydrogenase
A2cp1_0883	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_0884	ENOG4105BZU	Histidine kinase
A2cp1_0885	ENOG4105DA5	(ABC) transporter
A2cp1_0886	ENOG4105E3A	(ABC) transporter
A2cp1_0888	ENOG4105C9U	ATP-dependent DNA helicase RecQ
A2cp1_0891	ENOG4108VWS	Yaeq family
A2cp1_0896	ENOG4105C9B	Cysteine desulfurase
A2cp1_0897	ENOG4108UNV	SUF system FeS assembly protein, NifU family
A2cp1_0901	ENOG4105CN1	protease
A2cp1_0903	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A2cp1_0906	ENOG4105WH1	Two component transcriptional regulator luxr family
A2cp1_0912	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
A2cp1_0916	ENOG4108V0P	LemA family
A2cp1_0921	ENOG4108JCI	Transcriptional regulator
A2cp1_0922	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A2cp1_0927	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
A2cp1_0935	ENOG4105DQE	DNA ligase
A2cp1_0938	ENOG4105D64	Mechanosensitive ion channel
A2cp1_0942	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
A2cp1_0943	ENOG4105C08	Histidine kinase
A2cp1_0945	ENOG4105C0X	amino acid
A2cp1_0949	ENOG4108SJC	Membrane
A2cp1_0952	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
A2cp1_0955	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
A2cp1_0959	ENOG410690C	hydroxylamine oxidase
A2cp1_0961	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
A2cp1_0963	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
A2cp1_0965	ENOG4107STQ	Multicopper oxidase
A2cp1_0976	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_0980	ENOG4108IQK	o-acetylhomoserine
A2cp1_0983	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
A2cp1_0984	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
A2cp1_0987	ENOG4107QJE	Chromosome Partitioning Protein
A2cp1_0988	ENOG4105JQN	Transcriptional regulator
A2cp1_0990	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
A2cp1_0991	ENOG4108NVM	synthesis repressor PhaR
A2cp1_0994	ENOG41063NY	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
A2cp1_0995	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A2cp1_1001	ENOG4105C7Z	Conserved Protein
A2cp1_1006	ENOG4107QI1	Mate efflux family protein
A2cp1_1008	ENOG4107SFI	Major Facilitator superfamily
A2cp1_1013	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
A2cp1_1020	ENOG4105DQE	DNA ligase
A2cp1_1024	ENOG4105CYC	Transferase
A2cp1_1026	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A2cp1_1028	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
A2cp1_1034	ENOG4108JUA	Transcriptional regulator
A2cp1_1035	ENOG4105C2C	drug resistance transporter, Bcr CflA
A2cp1_1042	ENOG4105CYW	agmatinase
A2cp1_1044	ENOG4105BZU	Histidine kinase
A2cp1_1045	ENOG4108UXN	response regulator
A2cp1_1046	ENOG4105ERG	peptidase m48, ste24p
A2cp1_1049	ENOG4105VEQ	Cold shock protein
A2cp1_1052	ENOG4108R96	Methyltransferase, YaeB family
A2cp1_1057	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
A2cp1_1059	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
A2cp1_1060	ENOG4105E0C	molybdate abc transporter
A2cp1_1061	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
A2cp1_1065	ENOG4105UIB	(ABC) transporter
A2cp1_1066	ENOG4105C2J	ABC transporter
A2cp1_1067	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
A2cp1_1077	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
A2cp1_1078	ENOG4108KZ5	Catalyzes the deacetylation of 1D-myo-inositol 2- acetamido-2-deoxy-alpha-D-glucopyranoside (GlcNAc-Ins) in the mycothiol biosynthesis pathway (By similarity)
A2cp1_1084	ENOG4108UXE	Protein tyrosine phosphatase
A2cp1_1085	ENOG4105D6J	arsenicaL-resistance protein
A2cp1_1091	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A2cp1_1094	ENOG4108KB2	LysR family Transcriptional regulator
A2cp1_1103	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
A2cp1_1120	ENOG4107R4Q	Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone (By similarity)
A2cp1_1122	ENOG4105W5Q	DNA repair protein (RadC
A2cp1_1123	ENOG4105FA0	parb-like partition protein
A2cp1_1126	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
A2cp1_1138	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
A2cp1_1160	ENOG4107QRT	dEAD DEAH box helicase
A2cp1_1166	ENOG4105CHJ	isochorismatase hydrolase
A2cp1_1167	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
A2cp1_1170	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
A2cp1_1172	ENOG4105D48	metallophosphoesterase
A2cp1_1174	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
A2cp1_1175	ENOG4105C3J	Cysteine desulfurase
A2cp1_1177	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
A2cp1_1179	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A2cp1_1181	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
A2cp1_1183	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_1185	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
A2cp1_1189	ENOG4108IAJ	Nad-dependent epimerase dehydratase
A2cp1_1191	ENOG4105CK5	oxidoreductase
A2cp1_1192	ENOG4107TYR	Glycosyl Transferase
A2cp1_1195	ENOG4105BZ1	(ABC) transporter
A2cp1_1197	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A2cp1_1198	ENOG4105EMU	Dehydrogenase
A2cp1_1199	ENOG4105ES5	Histidine kinase
A2cp1_1202	ENOG4107QPV	Serine Threonine protein kinase
A2cp1_1204	ENOG4107RFW	hydrolase family 57
A2cp1_1208	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A2cp1_1209	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A2cp1_1214	ENOG4105GYT	Protein of unknown function (DUF1009)
A2cp1_1216	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
A2cp1_1217	ENOG4105D4P	Coproporphyrinogen iii oxidase
A2cp1_1218	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
A2cp1_1219	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A2cp1_1221	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A2cp1_1222	ENOG41084YM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
A2cp1_1223	ENOG4105ETX	regulatoR
A2cp1_1224	ENOG4105CTB	Polyprenyl synthetase
A2cp1_1226	ENOG4105DX0	Hemolysin A
A2cp1_1233	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
A2cp1_1239	ENOG4105BZU	Histidine kinase
A2cp1_1243	ENOG4105C0H	protease
A2cp1_1245	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A2cp1_1246	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A2cp1_1247	ENOG4105ETX	regulatoR
A2cp1_1249	ENOG4105DZP	Membrane-associated zinc metalloprotease
A2cp1_1250	ENOG4105NBF	ammecr1 domain protein
A2cp1_1251	ENOG4105E09	nadh pyrophosphatase
A2cp1_1259	ENOG4105BZU	Histidine kinase
A2cp1_1261	ENOG4105C1G	acyl-Coa dehydrogenase
A2cp1_1262	ENOG4105VF7	tolerance protein
A2cp1_1264	ENOG4108SPH	protein kinase (EC 2.7.11.1)
A2cp1_1265	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A2cp1_1266	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
A2cp1_1268	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
A2cp1_1269	ENOG4105NAU	thioesterase Superfamily protein
A2cp1_1270	ENOG4105C9K	Endothelin-converting enzyme 1
A2cp1_1278	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
A2cp1_1279	ENOG4107T4V	d-proline reductase
A2cp1_1284	ENOG4105CXV	gliding motility protein
A2cp1_1286	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
A2cp1_1302	ENOG4105CAR	Terminase, large subunit
A2cp1_1315	ENOG4105CDU	Replicative dna helicase
A2cp1_1321	ENOG4105DMQ	Methyltransferase
A2cp1_1322	ENOG4105C8Q	Methyl-accepting chemotaxis
A2cp1_1323	ENOG4105DQ4	alcohol dehydrogenase
A2cp1_1326	ENOG4105CEY	Amp-dependent synthetase and ligase
A2cp1_1327	ENOG4105QUH	Domain of unknown function (DUF2088)
A2cp1_1331	ENOG4108J2R	molybdopterin oxidoreductase
A2cp1_1332	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
A2cp1_1336	ENOG4105C58	cytochrome c oxidase accessory protein ccog
A2cp1_1350	ENOG4105CX6	glutaminyL-tRNA synthetase
A2cp1_1355	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
A2cp1_1359	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
A2cp1_1361	ENOG4105CFG	Acts as a chaperone (By similarity)
A2cp1_1362	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A2cp1_1364	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
A2cp1_1366	ENOG4105KPV	Transcriptional regulator
A2cp1_1367	ENOG4105DB7	PHP domain protein
A2cp1_1368	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A2cp1_1369	ENOG4105C8S	subunit m
A2cp1_1371	ENOG41080FQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A2cp1_1373	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A2cp1_1374	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
A2cp1_1376	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A2cp1_1378	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A2cp1_1381	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
A2cp1_1384	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
A2cp1_1385	ENOG41081QM	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A2cp1_1388	ENOG4105EYM	Major Facilitator superfamily
A2cp1_1389	ENOG4105DCG	PHP domain protein
A2cp1_1391	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
A2cp1_1395	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A2cp1_1400	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
A2cp1_1401	ENOG4105KME	endoribonuclease L-psp
A2cp1_1403	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
A2cp1_1404	ENOG4107T5V	SNARE associated Golgi
A2cp1_1405	ENOG4105JFG	SpoIID LytB domain protein
A2cp1_1408	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
A2cp1_1409	ENOG4105VIE	preprotein translocase, subunit YajC
A2cp1_1410	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A2cp1_1411	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
A2cp1_1415	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
A2cp1_1416	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
A2cp1_1419	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
A2cp1_1424	ENOG4107TE5	Lipid kinase
A2cp1_1426	ENOG4105C0D	helicase
A2cp1_1431	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
A2cp1_1435	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
A2cp1_1438	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
A2cp1_1439	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
A2cp1_1441	ENOG4105EIE	fructose-bisphosphate aldolase
A2cp1_1449	ENOG4105DFA	alanine racemase domain protein
A2cp1_1451	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
A2cp1_1454	ENOG4105CJN	penicillin-binding protein
A2cp1_1455	ENOG4105CNI	cell division protein FtsW
A2cp1_1456	ENOG4105K63	Thioredoxin
A2cp1_1459	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
A2cp1_1460	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
A2cp1_1463	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
A2cp1_1467	ENOG4105C0B	DNA polymerase III (alpha subunit)
A2cp1_1475	ENOG4105DDR	sarcosine oxidase (Beta subunit)
A2cp1_1476	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A2cp1_1480	ENOG4107QQG	Dehydrogenase
A2cp1_1484	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
A2cp1_1486	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A2cp1_1488	ENOG4105C12	Phosphoribosylglycinamide synthetase
A2cp1_1494	ENOG4105EY8	ABC transporter
A2cp1_1497	ENOG4105K64	Glycosyl transferase, family 2
A2cp1_1500	ENOG4105D3Q	Sugar transferase
A2cp1_1501	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
A2cp1_1503	ENOG4105D52	delta-aminolevulinic acid dehydratase
A2cp1_1506	ENOG4105CPF	Cell wall formation (By similarity)
A2cp1_1514	ENOG4105BZU	Histidine kinase
A2cp1_1515	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A2cp1_1516	ENOG4105DUM	transcriptional regulator, lysR family
A2cp1_1523	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A2cp1_1524	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A2cp1_1526	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
A2cp1_1528	ENOG4105EJ9	Membrane
A2cp1_1529	ENOG41080XQ	Signal transduction protein with cbs domains
A2cp1_1530	ENOG4108IV0	ABC, transporter
A2cp1_1531	ENOG4105C0Z	ABC transporter
A2cp1_1532	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
A2cp1_1533	ENOG4105C32	Amino acid ABC transporter (Permease)
A2cp1_1536	ENOG4105C98	muts2 protein
A2cp1_1543	ENOG4105EMN	RNA polymerase sigma factor
A2cp1_1547	ENOG4105EHZ	conserved protein UCP016719
A2cp1_1551	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
A2cp1_1556	ENOG4105EQJ	Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide (By similarity)
A2cp1_1562	ENOG4105D78	K07001 NTE family protein
A2cp1_1565	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
A2cp1_1566	ENOG4105BZU	Histidine kinase
A2cp1_1569	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
A2cp1_1570	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
A2cp1_1571	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
A2cp1_1575	ENOG4105CJR	Integral membrane protein (MviN
A2cp1_1581	ENOG4105EMN	RNA polymerase sigma factor
A2cp1_1583	ENOG4105DR4	Methyltransferase
A2cp1_1587	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
A2cp1_1589	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
A2cp1_1591	ENOG4107QX8	SPFH domain, Band 7 family protein
A2cp1_1593	ENOG4105D44	asparaginase
A2cp1_1594	ENOG4105CHU	acetyl-coa acetyltransferase
A2cp1_1595	ENOG4105D6N	CoA-transferase, subunit a
A2cp1_1599	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
A2cp1_1605	ENOG4105SG9	biopolymer transport protein, ExbD
A2cp1_1606	ENOG4108PAU	MotA TolQ exbB proton channel
A2cp1_1607	ENOG4105D0M	Protease HtpX homolog
A2cp1_1611	ENOG4108Z0R	Transferase
A2cp1_1613	ENOG4108VD1	dedA family
A2cp1_1614	ENOG4105CFG	Acts as a chaperone (By similarity)
A2cp1_1615	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A2cp1_1616	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
A2cp1_1620	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_1622	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
A2cp1_1624	ENOG4108P3C	
A2cp1_1626	ENOG4105FDK	ABC transporter
A2cp1_1628	ENOG4108UQV	Membrane
A2cp1_1631	ENOG4105DXX	methyltransferase
A2cp1_1633	ENOG4105CHM	Aminotransferase
A2cp1_1638	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
A2cp1_1641	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
A2cp1_1642	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
A2cp1_1643	ENOG4108W6C	Dehydrogenase
A2cp1_1645	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
A2cp1_1654	ENOG4105CIR	epoxide hydrolase
A2cp1_1660	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A2cp1_1665	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
A2cp1_1666	ENOG4105W2Z	cytochrome C, class I
A2cp1_1671	ENOG4108XRS	Monoheme cytochrome SoxX (Sulfur oxidation)
A2cp1_1672	ENOG4105CGH	5'-nucleotidase
A2cp1_1673	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
A2cp1_1677	ENOG4105BZ9	Cytochrome C oxidase, subunit I
A2cp1_1681	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
A2cp1_1690	ENOG4105R8A	Heat shock protein
A2cp1_1696	ENOG4105EMN	RNA polymerase sigma factor
A2cp1_1702	ENOG4105C26	Dehydrogenase
A2cp1_1707	ENOG4105BZU	Histidine kinase
A2cp1_1708	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_1711	ENOG4105BZS	acriflavin resistance protein
A2cp1_1720	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
A2cp1_1721	ENOG4105E9K	Isocitrate dehydrogenase
A2cp1_1722	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
A2cp1_1727	ENOG4105C2M	dna polymerase I
A2cp1_1730	ENOG4108YZA	Nitrogen regulatory protein pii
A2cp1_1732	ENOG4105FG0	Nitroreductase
A2cp1_1733	ENOG4105CC0	LysR family Transcriptional regulator
A2cp1_1735	ENOG4107RSM	transcriptional regulator
A2cp1_1737	ENOG4105BZU	Histidine kinase
A2cp1_1739	ENOG4107T8Q	Glycosyl transferase (Group 1
A2cp1_1740	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
A2cp1_1742	ENOG4105EUB	pirin domain protein
A2cp1_1745	ENOG4108R4R	Iron-regulated virulence regulatory protein
A2cp1_1746	ENOG4105K63	Thioredoxin
A2cp1_1751	ENOG4105DUM	transcriptional regulator, lysR family
A2cp1_1754	ENOG4105CRE	cytochrome C
A2cp1_1755	ENOG4108RAC	Rubrerythrin
A2cp1_1756	ENOG4105BZU	Histidine kinase
A2cp1_1762	ENOG4105C8Q	Methyl-accepting chemotaxis
A2cp1_1763	ENOG4108V3W	Chemotaxis protein, CheW
A2cp1_1766	ENOG4108594	Permease of the drug metabolite transporter
A2cp1_1767	ENOG4108IV0	ABC, transporter
A2cp1_1768	ENOG4105C0Z	ABC transporter
A2cp1_1770	ENOG4105CP9	extracellular ligand-binding receptor
A2cp1_1773	ENOG4105E63	Pfam:DUF178
A2cp1_1775	ENOG4105DQQ	Major facilitator superfamily MFS_1
A2cp1_1778	ENOG4108IUE	nitrate reductase beta subunit
A2cp1_1781	ENOG4105BZU	Histidine kinase
A2cp1_1790	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
A2cp1_1792	ENOG4105C5H	ABC transporter
A2cp1_1795	ENOG4108R3E	Dna-3-methyladenine glycosylase i
A2cp1_1796	ENOG4105CEP	NADH dehydrogenase
A2cp1_1797	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
A2cp1_1799	ENOG4105DB1	molybdopterin oxidoreductase
A2cp1_1800	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
A2cp1_1801	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_1802	ENOG4105BZU	Histidine kinase
A2cp1_1811	ENOG4107QIV	Cytochrome c biogenesis protein
A2cp1_1815	ENOG4105HDK	L-asparaginase
A2cp1_1817	ENOG4105DTD	Dehydrogenase
A2cp1_1819	ENOG4105C32	Amino acid ABC transporter (Permease)
A2cp1_1821	ENOG4108IV0	ABC, transporter
A2cp1_1822	ENOG4105C0Z	ABC transporter
A2cp1_1824	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
A2cp1_1826	ENOG4107QSN	dihydrolipoamide acetyltransferase
A2cp1_1827	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
A2cp1_1833	ENOG4107TPY	serine threonine protein kinase
A2cp1_1837	ENOG4105CPC	Aldo Keto reductase
A2cp1_1838	ENOG4108RRZ	Transcription elongation factor GreB
A2cp1_1842	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
A2cp1_1844	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
A2cp1_1847	ENOG4105DCF	alanine dehydrogenase
A2cp1_1848	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A2cp1_1853	ENOG4105CRE	cytochrome C
A2cp1_1854	ENOG4105BZU	Histidine kinase
A2cp1_1855	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_1861	ENOG4107EFR	Flavocytochrome c
A2cp1_1863	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
A2cp1_1865	ENOG4107QRT	dEAD DEAH box helicase
A2cp1_1866	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
A2cp1_1867	ENOG4105BZU	Histidine kinase
A2cp1_1869	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
A2cp1_1870	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
A2cp1_1871	ENOG4105CTQ	phosphohexokinase
A2cp1_1872	ENOG4105C28	cystathionine
A2cp1_1876	ENOG4108URH	decarboxylase
A2cp1_1877	ENOG4105CIN	aminoacyl-histidine dipeptidase
A2cp1_1880	ENOG4105CPC	Aldo Keto reductase
A2cp1_1883	ENOG4105MPN	Membrane
A2cp1_1885	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
A2cp1_1886	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
A2cp1_1887	ENOG4105EXC	Acyl-transferase
A2cp1_1888	ENOG4107GFK	fumarate
A2cp1_1889	ENOG4107S4F	acyltransferase, ws dgat mgat
A2cp1_1895	ENOG4105C5H	ABC transporter
A2cp1_1898	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A2cp1_1900	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
A2cp1_1902	ENOG4105DPN	Oligoendopeptidase f
A2cp1_1906	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
A2cp1_1915	ENOG4105DWF	phosphomethylpyrimidine kinase
A2cp1_1917	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
A2cp1_1920	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A2cp1_1921	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A2cp1_1924	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
A2cp1_1926	ENOG4105DN3	alpha-2-macroglobulin domain protein
A2cp1_1927	ENOG4108JQB	penicillin-binding protein 1C
A2cp1_1932	ENOG4107QZ7	Cellulose synthase catalytic subunit
A2cp1_1941	ENOG4105BZS	acriflavin resistance protein
A2cp1_1944	ENOG4105VW4	glutaredoxin 3
A2cp1_1945	ENOG4105D0M	Protease HtpX homolog
A2cp1_1946	ENOG41063Z6	transcriptional regulator, lysR family
A2cp1_1947	ENOG4105DU1	integral membrane protein, terc
A2cp1_1949	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
A2cp1_1951	ENOG4105CIY	formyltetrahydrofolate deformylase
A2cp1_1952	ENOG4105BZU	Histidine kinase
A2cp1_1954	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_1956	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
A2cp1_1957	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
A2cp1_1958	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
A2cp1_1966	ENOG4105WH1	Two component transcriptional regulator luxr family
A2cp1_1969	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
A2cp1_1970	ENOG4105BZU	Histidine kinase
A2cp1_1972	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A2cp1_1979	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
A2cp1_1982	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
A2cp1_1985	ENOG4105C7K	acetolactate synthase
A2cp1_1991	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A2cp1_1992	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
A2cp1_1997	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
A2cp1_1998	ENOG4105EUJ	GTP cyclohydrolase i
A2cp1_1999	ENOG4105CHR	reductase
A2cp1_2000	ENOG4105CQB	FAD linked oxidase domain protein
A2cp1_2001	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
A2cp1_2002	ENOG4105DQU	oxidoreductase, subunit beta
A2cp1_2004	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
A2cp1_2005	ENOG4105DQU	oxidoreductase, subunit beta
A2cp1_2009	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
A2cp1_2011	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
A2cp1_2012	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
A2cp1_2016	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A2cp1_2017	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A2cp1_2026	ENOG4108BAG	50s ribosomal protein l29
A2cp1_2035	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
A2cp1_2038	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
A2cp1_2043	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
A2cp1_2049	ENOG4105VB6	UPF0109 protein
A2cp1_2050	ENOG41082N4	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
A2cp1_2054	ENOG41082RQ	UPF0102 protein
A2cp1_2057	ENOG4105BZU	Histidine kinase
A2cp1_2058	ENOG4107SC1	transglycosylase
A2cp1_2063	ENOG4105C34	Pseudouridine synthase
A2cp1_2066	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
A2cp1_2068	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
A2cp1_2072	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
A2cp1_2080	ENOG4105C34	Pseudouridine synthase
A2cp1_2083	ENOG4105DHJ	ABC, transporter
A2cp1_2087	ENOG4108JQ1	Dehydrogenase
A2cp1_2094	ENOG4105E39	Enoyl-CoA hydratase
A2cp1_2095	ENOG4105US7	Histidine kinase
A2cp1_2100	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A2cp1_2101	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
A2cp1_2102	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
A2cp1_2104	ENOG4105CPP	Dehydrogenase, E1 component
A2cp1_2106	ENOG4105F8V	Hydrolase, tatD family
A2cp1_2107	ENOG4105CUZ	uba thif-type nad fad binding protein
A2cp1_2108	ENOG4107QN2	dihydrolipoyl dehydrogenase
A2cp1_2109	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
A2cp1_2110	ENOG4107QPV	Serine Threonine protein kinase
A2cp1_2111	ENOG4105EPD	Oligopeptide transporter, Opt family
A2cp1_2115	ENOG4105CZK	Aspartate kinase
A2cp1_2117	ENOG4105BZM	domain protein
A2cp1_2122	ENOG4105C4R	Atp-dependent dna helicase
A2cp1_2123	ENOG4105CFG	Acts as a chaperone (By similarity)
A2cp1_2150	ENOG4105BZU	Histidine kinase
A2cp1_2152	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
A2cp1_2156	ENOG4105CY0	Metallo-Beta-Lactamase
A2cp1_2160	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A2cp1_2161	ENOG4105C0H	protease
A2cp1_2166	ENOG4105D82	Glutamate dehydrogenase
A2cp1_2172	ENOG4105WH1	Two component transcriptional regulator luxr family
A2cp1_2175	ENOG4105BZU	Histidine kinase
A2cp1_2177	ENOG4108IJ0	Aspartate ammonia-lyase
A2cp1_2178	ENOG4105DS2	Anaerobic c4-dicarboxylate transporter
A2cp1_2179	ENOG4108Z9W	Outer membrane porin
A2cp1_2195	ENOG4105PGM	cation diffusion facilitator family transporter
A2cp1_2196	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
A2cp1_2197	ENOG4108IJ6	ABC transporter
A2cp1_2199	ENOG4108I5D	sulfate abc transporter
A2cp1_2200	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
A2cp1_2201	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
A2cp1_2202	ENOG4105C11	sulfate adenylyltransferase), subunit 2
A2cp1_2204	ENOG4106H78	methyltransferase
A2cp1_2208	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
A2cp1_2213	ENOG4105CHM	Aminotransferase
A2cp1_2216	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A2cp1_2217	ENOG4105CEV	competence damage-inducible protein
A2cp1_2227	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_2229	ENOG4105D9P	serine threonine protein kinase
A2cp1_2231	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A2cp1_2240	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
A2cp1_2242	ENOG410802X	bacteriophage n4 adsorption protein b
A2cp1_2250	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
A2cp1_2251	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A2cp1_2253	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
A2cp1_2254	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A2cp1_2257	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
A2cp1_2258	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A2cp1_2259	ENOG4108Z4T	Peptidase M50
A2cp1_2260	ENOG4105C31	Tryptophanyl-tRNA synthetase
A2cp1_2261	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
A2cp1_2262	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
A2cp1_2263	ENOG4105FE9	pseudouridine synthase
A2cp1_2267	ENOG4105EMN	RNA polymerase sigma factor
A2cp1_2269	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
A2cp1_2270	ENOG4105D7N	magnesium and cobalt transport protein CorA
A2cp1_2272	ENOG4105D1F	ATP-binding protein
A2cp1_2278	ENOG4105BZU	Histidine kinase
A2cp1_2279	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
A2cp1_2280	ENOG4105E39	Enoyl-CoA hydratase
A2cp1_2281	ENOG4105C1G	acyl-Coa dehydrogenase
A2cp1_2282	ENOG4105C1G	acyl-Coa dehydrogenase
A2cp1_2283	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
A2cp1_2287	ENOG4108M19	cytochrome C
A2cp1_2289	ENOG4105M6F	mutator MutT protein
A2cp1_2292	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
A2cp1_2293	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
A2cp1_2296	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
A2cp1_2297	ENOG4105DJT	lAO AO transport system ATPase
A2cp1_2299	ENOG4105C1G	acyl-Coa dehydrogenase
A2cp1_2300	ENOG4107QX3	carboxylase
A2cp1_2301	ENOG4105E39	Enoyl-CoA hydratase
A2cp1_2308	ENOG4105CBT	Fructose-1,6-bisphosphatase
A2cp1_2310	ENOG4105D6E	homoserine dehydrogenase
A2cp1_2317	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
A2cp1_2320	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
A2cp1_2322	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
A2cp1_2323	ENOG4108HMX	isocitrate dehydrogenase (NADP)
A2cp1_2325	ENOG4105BZU	Histidine kinase
A2cp1_2328	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
A2cp1_2331	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
A2cp1_2333	ENOG4105C3F	Signal peptidase i
A2cp1_2335	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
A2cp1_2338	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
A2cp1_2342	ENOG41080RH	Thioredoxin
A2cp1_2343	ENOG4108UYB	regulatoR
A2cp1_2344	ENOG4105BZU	Histidine kinase
A2cp1_2348	ENOG4107SC1	transglycosylase
A2cp1_2353	ENOG4105ETX	regulatoR
A2cp1_2357	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A2cp1_2364	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
A2cp1_2367	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
A2cp1_2368	ENOG4105C2N	RNA methyltransferase TrmH family group 3
A2cp1_2370	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A2cp1_2371	ENOG4105CFG	Acts as a chaperone (By similarity)
A2cp1_2373	ENOG4108Z43	UPF0250 protein
A2cp1_2374	ENOG4108IAB	Phoh family
A2cp1_2375	ENOG4105BZU	Histidine kinase
A2cp1_2378	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A2cp1_2379	ENOG4107Z3H	Transcriptional regulator, TetR family
A2cp1_2384	ENOG41079HR	Phosphate-Selective Porin O and P
A2cp1_2388	ENOG41090R7	Ferric uptake
A2cp1_2397	ENOG4105BZU	Histidine kinase
A2cp1_2398	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_2399	ENOG4105BZU	Histidine kinase
A2cp1_2404	ENOG4105CYN	Serine protein kinase
A2cp1_2404	ENOG4105CYN	Serine protein kinase
A2cp1_2405	ENOG4105CFG	Acts as a chaperone (By similarity)
A2cp1_2407	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
A2cp1_2410	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
A2cp1_2414	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
A2cp1_2415	ENOG41081QJ	UBA THIF-type NAD FAD binding
A2cp1_2417	ENOG4105D06	uba thif-type nad fad binding protein
A2cp1_2419	ENOG4105CFG	Acts as a chaperone (By similarity)
A2cp1_2421	ENOG4108Z4U	Ferredoxin
A2cp1_2423	ENOG4105CP7	Triose-phosphate isomerase
A2cp1_2427	ENOG4105DZ0	fad dependent oxidoreductase
A2cp1_2435	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A2cp1_2439	ENOG4105CAT	Cytidine monophosphate kinase
A2cp1_2441	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
A2cp1_2447	ENOG4105CGP	Urocanate hydratase
A2cp1_2452	ENOG4105K8N	protein family UPF0079, ATPase
A2cp1_2453	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
A2cp1_2455	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
A2cp1_2456	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
A2cp1_2458	ENOG4105C8B	TIGR00159 family
A2cp1_2460	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A2cp1_2461	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
A2cp1_2464	ENOG4105BZU	Histidine kinase
A2cp1_2467	ENOG4105K70	DNA-binding protein
A2cp1_2468	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
A2cp1_2469	ENOG4108UYI	beta-alanyl-CoA ammonia lyase
A2cp1_2470	ENOG4107CHF	5,6-aminomutase beta subunit
A2cp1_2472	ENOG4105EQ5	D-Lysine 5,6-aminomutase alpha subunit
A2cp1_2473	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
A2cp1_2474	ENOG4105BZU	Histidine kinase
A2cp1_2475	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
A2cp1_2478	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_2481	ENOG410624X	efflux transporter, rnd family, mfp subunit
A2cp1_2483	ENOG4105BZU	Histidine kinase
A2cp1_2484	ENOG4105BZU	Histidine kinase
A2cp1_2489	ENOG4105C8Q	Methyl-accepting chemotaxis
A2cp1_2493	ENOG4108YYC	ycei family
A2cp1_2494	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
A2cp1_2498	ENOG4105BZU	Histidine kinase
A2cp1_2499	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_2500	ENOG4107YZX	Universal stress protein
A2cp1_2505	ENOG4105BZP	glycoside hydrolase 15-related
A2cp1_2506	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
A2cp1_2509	ENOG4108J5G	6-phosphogluconate dehydrogenase
A2cp1_2511	ENOG4108JZA	Homocitrate synthase
A2cp1_2515	ENOG4105K6H	D-cysteine desulfhydrase
A2cp1_2519	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
A2cp1_2520	ENOG4105DNZ	Alpha Beta Hydrolase
A2cp1_2524	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
A2cp1_2543	ENOG4105CMM	transposase
A2cp1_2545	ENOG41067HS	methyltransferase
A2cp1_2547	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
A2cp1_2552	ENOG4108JUA	Transcriptional regulator
A2cp1_2553	ENOG4107QT6	homoserine O-acetyltransferase
A2cp1_2557	ENOG4108ZC9	flagellar basal-body rod protein flgc
A2cp1_2558	ENOG41084DA	flagellar hook-basal body complex protein fliE
A2cp1_2559	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
A2cp1_2560	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
A2cp1_2562	ENOG4108JIR	Flagellum-specific ATP synthase
A2cp1_2566	ENOG4105BZE	flagellar hook protein, FlgE
A2cp1_2568	ENOG4105E14	MotA TolQ exbB proton channel
A2cp1_2569	ENOG4105ER2	Ompa motb domain protein
A2cp1_2570	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A2cp1_2571	ENOG4105BZU	Histidine kinase
A2cp1_2572	ENOG4108V3W	Chemotaxis protein, CheW
A2cp1_2573	ENOG4105C8Q	Methyl-accepting chemotaxis
A2cp1_2574	ENOG4105CBS	Chea signal transduction histidine kinase
A2cp1_2575	ENOG4108VYJ	response regulator receiver protein
A2cp1_2578	ENOG4108V3W	Chemotaxis protein, CheW
A2cp1_2579	ENOG4105C8Q	Methyl-accepting chemotaxis
A2cp1_2580	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A2cp1_2581	ENOG4108094	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
A2cp1_2582	ENOG4105BZU	Histidine kinase
A2cp1_2583	ENOG4105CBS	Chea signal transduction histidine kinase
A2cp1_2583	ENOG4105CBS	Chea signal transduction histidine kinase
A2cp1_2585	ENOG4108MGY	Histidine kinase
A2cp1_2586	ENOG4108HU6	Metal dependent phosphohydrolase
A2cp1_2588	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
A2cp1_2589	ENOG4105DD5	Flagellar motor switch protein
A2cp1_2591	ENOG4105CN7	Flagellar biosynthetic protein FliP
A2cp1_2592	ENOG4105VS8	Flagellar biosynthetic protein fliq
A2cp1_2593	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
A2cp1_2594	ENOG4105D00	flagellar biosynthetic protein flhB
A2cp1_2595	ENOG4105D7B	Flagellar biosynthesis protein flha
A2cp1_2596	ENOG4105FZW	flagellar biosynthesis regulator FlhF
A2cp1_2598	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A2cp1_2601	ENOG4105KTQ	flagellar basal-body rod protein
A2cp1_2602	ENOG4105CGA	flagellar basal-body rod protein FlgG
A2cp1_2606	ENOG4105DR5	peptidase
A2cp1_2611	ENOG4105I03	Flagellin
A2cp1_2612	ENOG4107RT6	flagellar hook-associated
A2cp1_2615	ENOG4105I03	Flagellin
A2cp1_2617	ENOG4107TVC	Glycosyl transferase, family 2
A2cp1_2620	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
A2cp1_2621	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
A2cp1_2623	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
A2cp1_2624	ENOG41068KF	Universal stress protein
A2cp1_2625	ENOG4105CJW	magnesium transporter
A2cp1_2626	ENOG4108TQ9	Histidine kinase
A2cp1_2627	ENOG4106322	response regulator
A2cp1_2628	ENOG4105BZU	Histidine kinase
A2cp1_2629	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_2630	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A2cp1_2638	ENOG4108RWI	nicotinamidase
A2cp1_2639	ENOG4105EQI	Metal Dependent Phosphohydrolase
A2cp1_2641	ENOG4105F8V	Hydrolase, tatD family
A2cp1_2642	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
A2cp1_2644	ENOG4107QRG	dna polymerase iii
A2cp1_2646	ENOG4105C2M	dna polymerase I
A2cp1_2652	ENOG4105D7K	pfkb domain protein
A2cp1_2658	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
A2cp1_2659	ENOG4105E4C	Lytic transglycosylase catalytic
A2cp1_2665	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A2cp1_2667	ENOG4105E55	glycerol-3-phosphate acyltransferase
A2cp1_2669	ENOG4107TK4	histidinol-phosphate phosphatase
A2cp1_2671	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
A2cp1_2672	ENOG4107QHF	type ii secretion system protein e
A2cp1_2675	ENOG4105F0N	pyrophosphate phospho-hydrolase
A2cp1_2676	ENOG4105D7W	serine acetyltransferase
A2cp1_2679	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
A2cp1_2681	ENOG4105VEQ	Cold shock protein
A2cp1_2684	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
A2cp1_2686	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
A2cp1_2695	ENOG4107Z3H	Transcriptional regulator, TetR family
A2cp1_2696	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
A2cp1_2699	ENOG4108IDZ	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
A2cp1_2700	ENOG4105IJJ	transcriptional regulator, crp fnr family
A2cp1_2703	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
A2cp1_2706	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
A2cp1_2709	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
A2cp1_2712	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
A2cp1_2714	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A2cp1_2717	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A2cp1_2721	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
A2cp1_2723	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
A2cp1_2724	ENOG4105VEQ	Cold shock protein
A2cp1_2728	ENOG4105HHA	aminodeoxychorismate lyase
A2cp1_2729	ENOG4105CYN	Serine protein kinase
A2cp1_2730	ENOG4106AKX	UPF0229 protein
A2cp1_2731	ENOG4105ED1	spovr family
A2cp1_2735	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A2cp1_2740	ENOG4108YZY	peptidylprolyl cis-trans isomerase
A2cp1_2742	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
A2cp1_2743	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
A2cp1_2744	ENOG4105NZG	Ferredoxin
A2cp1_2748	ENOG4105JQZ	Methyltransferase
A2cp1_2756	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
A2cp1_2758	ENOG4105CHR	reductase
A2cp1_2759	ENOG4105BZU	Histidine kinase
A2cp1_2768	ENOG4105EBX	v-type atpase
A2cp1_2770	ENOG4105BZU	Histidine kinase
A2cp1_2772	ENOG4108W2P	Methyl-accepting chemotaxis
A2cp1_2773	ENOG4105CBS	Chea signal transduction histidine kinase
A2cp1_2774	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A2cp1_2775	ENOG4105BZU	Histidine kinase
A2cp1_2777	ENOG4107V40	secretion protein, HlyD family
A2cp1_2781	ENOG4108IG5	Transcriptional regulator
A2cp1_2785	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
A2cp1_2786	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
A2cp1_2787	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
A2cp1_2788	ENOG4105DSJ	YicC domain protein
A2cp1_2789	ENOG4105W49	UPF0434 protein
A2cp1_2791	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
A2cp1_2792	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
A2cp1_2793	ENOG4105D1S	lipid A biosynthesis
A2cp1_2795	ENOG4105DKP	glycosyl transferase, family 9
A2cp1_2796	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
A2cp1_2798	ENOG4105BZ1	(ABC) transporter
A2cp1_2799	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
A2cp1_2800	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A2cp1_2803	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
A2cp1_2804	ENOG41081FY	multiple antibiotic resistance (MarC)-related
A2cp1_2805	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
A2cp1_2812	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
A2cp1_2813	ENOG4107QY8	reductase
A2cp1_2816	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A2cp1_2820	ENOG4108PQP	glycosyl transferase group 1
A2cp1_2825	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A2cp1_2827	ENOG4105CHW	UPF0052 protein
A2cp1_2830	ENOG4107YJ4	chain length determinant protein
A2cp1_2835	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_2839	ENOG4105F0I	Aminotransferase
A2cp1_2841	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A2cp1_2852	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
A2cp1_2862	ENOG4105SYT	Methylenetetrahydrofolate reductase
A2cp1_2863	ENOG4108RRZ	Transcription elongation factor GreB
A2cp1_2870	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
A2cp1_2875	ENOG4105CFG	Acts as a chaperone (By similarity)
A2cp1_2877	ENOG4105DBV	ornithine carbamoyltransferase
A2cp1_2878	ENOG4105C8Y	Acetylornithine aminotransferase
A2cp1_2879	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
A2cp1_2881	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A2cp1_2885	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
A2cp1_2887	ENOG4108WZM	domain protein
A2cp1_2889	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
A2cp1_2891	ENOG4106EEU	Response regulator receiver domain
A2cp1_2893	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
A2cp1_2896	ENOG4105E2K	Glycosyl transferase (Group 1
A2cp1_2898	ENOG4107VGF	ig domain protein group 2 domain protein
A2cp1_2899	ENOG4105CZX	twitching motility protein
A2cp1_2901	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
A2cp1_2902	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
A2cp1_2904	ENOG4105CTJ	Metal Dependent Phosphohydrolase
A2cp1_2906	ENOG4108UJG	
A2cp1_2908	ENOG4105DXN	mazG family
A2cp1_2911	ENOG4105C8T	Leucyl-tRNA synthetase
A2cp1_2912	ENOG4105C5S	asparaginyl-tRNA synthetase
A2cp1_2913	ENOG4108VYJ	response regulator receiver protein
A2cp1_2914	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
A2cp1_2915	ENOG4105BZU	Histidine kinase
A2cp1_2917	ENOG4108V3W	Chemotaxis protein, CheW
A2cp1_2920	ENOG4105CBS	Chea signal transduction histidine kinase
A2cp1_2924	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
A2cp1_2929	ENOG4108YZG	isomerase
A2cp1_2930	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
A2cp1_2931	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
A2cp1_2932	ENOG4105CHR	reductase
A2cp1_2933	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
A2cp1_2934	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
A2cp1_2936	ENOG41085D1	50S ribosomal protein L32
A2cp1_2938	ENOG4107ZHV	Transcriptional regulator
A2cp1_2943	ENOG4105VC4	domain protein
A2cp1_2949	ENOG4105CPK	Glycosyl transferase (Group 1
A2cp1_2950	ENOG4105D3Q	Sugar transferase
A2cp1_2953	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
A2cp1_2956	ENOG4105CAQ	asparagine synthetase
A2cp1_2957	ENOG4107RMH	nh(3)-dependent nad( ) synthetase
A2cp1_2958	ENOG4105CEY	Amp-dependent synthetase and ligase
A2cp1_2971	ENOG4108PQP	glycosyl transferase group 1
A2cp1_2972	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
A2cp1_2976	ENOG4107T8Q	Glycosyl transferase (Group 1
A2cp1_2977	ENOG4105BZ8	glutamate synthase
A2cp1_2983	ENOG4105D9P	serine threonine protein kinase
A2cp1_2986	ENOG4105MIR	Phenylalanine 4-monooxygenase
A2cp1_2989	ENOG4105ETX	regulatoR
A2cp1_2991	ENOG4105BZU	Histidine kinase
A2cp1_3000	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
A2cp1_3025	ENOG4105D0M	Protease HtpX homolog
A2cp1_3027	ENOG4105CB2	alcohol dehydrogenase
A2cp1_3032	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
A2cp1_3034	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
A2cp1_3042	ENOG4105CK2	sodium dicarboxylate symporter
A2cp1_3045	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
A2cp1_3046	ENOG4105CQB	FAD linked oxidase domain protein
A2cp1_3047	ENOG4105CQB	FAD linked oxidase domain protein
A2cp1_3063	ENOG4108JGH	Tetr family transcriptional regulator
A2cp1_3070	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
A2cp1_3076	ENOG41089UC	methyltransferase, type 11
A2cp1_3082	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
A2cp1_3084	ENOG4105CH5	extracellular solute-binding protein, family 7
A2cp1_3085	ENOG4105CVJ	phosphoglycerate mutase
A2cp1_3087	ENOG4105C6K	Malic enzyme
A2cp1_3088	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
A2cp1_3089	ENOG4105K4T	epimerase
A2cp1_3092	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
A2cp1_3094	ENOG4105CEY	Amp-dependent synthetase and ligase
A2cp1_3095	ENOG410841Q	phosphoesterase PA-phosphatase related protein
A2cp1_3103	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
A2cp1_3106	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
A2cp1_3107	ENOG4105EB3	Histidine kinase
A2cp1_3117	ENOG4105CND	Glycosyl transferase, family 2
A2cp1_3118	ENOG4107BJW	polysaccharide deacetylase
A2cp1_3120	ENOG4106855	Competence protein
A2cp1_3130	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
A2cp1_3133	ENOG4105BZU	Histidine kinase
A2cp1_3134	ENOG4105BZU	Histidine kinase
A2cp1_3135	ENOG4105BZU	Histidine kinase
A2cp1_3137	ENOG4106F60	Histidine kinase
A2cp1_3138	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A2cp1_3149	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
A2cp1_3150	ENOG4105C1J	atp-dependent rna helicase
A2cp1_3151	ENOG4105BZU	Histidine kinase
A2cp1_3154	ENOG4108I5G	Major Facilitator superfamily
A2cp1_3158	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
A2cp1_3159	ENOG4105V2T	cytochrome C
A2cp1_3166	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A2cp1_3167	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
A2cp1_3168	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
A2cp1_3169	ENOG4108HRK	Histidine kinase
A2cp1_3170	ENOG4108NEV	two component transcriptional regulator, LytTR family
A2cp1_3172	ENOG4105DAA	L-lactate
A2cp1_3174	ENOG4107QR9	Iron-sulfur cluster binding protein
A2cp1_3177	ENOG41090JN	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
A2cp1_3181	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
A2cp1_3187	ENOG4105EN6	Membrane
A2cp1_3193	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
A2cp1_3194	ENOG4105C5R	Aminotransferase
A2cp1_3195	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A2cp1_3197	ENOG4105CFF	transcriptional regulator
A2cp1_3198	ENOG4107QP3	malate synthase g
A2cp1_3201	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
A2cp1_3202	ENOG4105CG3	alpha amylase, catalytic region
A2cp1_3205	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A2cp1_3206	ENOG4105W8H	transhydrogenase (subunit alpha
A2cp1_3207	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
A2cp1_3209	ENOG4105CEY	Amp-dependent synthetase and ligase
A2cp1_3210	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
A2cp1_3212	ENOG4105DQU	oxidoreductase, subunit beta
A2cp1_3213	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
A2cp1_3215	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
A2cp1_3217	ENOG4105W3S	hemerythrin-like, metal-binding protein
A2cp1_3218	ENOG4105CQB	FAD linked oxidase domain protein
A2cp1_3219	ENOG4107R37	Glutamate dehydrogenase
A2cp1_3222	ENOG4105C1G	acyl-Coa dehydrogenase
A2cp1_3225	ENOG4105CGD	Nad-dependent epimerase dehydratase
A2cp1_3227	ENOG4107SEY	Conserved Protein
A2cp1_3229	ENOG4107S2Z	UPF0761 membrane protein
A2cp1_3231	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
A2cp1_3232	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
A2cp1_3235	ENOG4105CPC	Aldo Keto reductase
A2cp1_3236	ENOG4107QXN	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
A2cp1_3239	ENOG4105CPC	Aldo Keto reductase
A2cp1_3240	ENOG4107R7Y	intracellular protease Pfpi family
A2cp1_3243	ENOG4105C1J	atp-dependent rna helicase
A2cp1_3248	ENOG4108Z66	YbaK ebsC protein
A2cp1_3249	ENOG4105ECJ	Glycosyl Transferase
A2cp1_3250	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
A2cp1_3257	ENOG4108XZB	Cytochrome c
A2cp1_3267	ENOG4108XZB	Cytochrome c
A2cp1_3276	ENOG4105CHM	Aminotransferase
A2cp1_3277	ENOG4105C8Q	Methyl-accepting chemotaxis
A2cp1_3278	ENOG4105CDH	Citrulline--aspartate ligase
A2cp1_3281	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
A2cp1_3285	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_3289	ENOG4105KVH	Transcriptional regulator
A2cp1_3290	ENOG4105ECR	NmrA family
A2cp1_3291	ENOG4105CPC	Aldo Keto reductase
A2cp1_3295	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
A2cp1_3299	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
A2cp1_3300	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
A2cp1_3302	ENOG4105DGW	oligopeptidase A
A2cp1_3303	ENOG4105BZU	Histidine kinase
A2cp1_3306	ENOG4105CJ1	ABC, transporter
A2cp1_3307	ENOG4105CJ1	ABC, transporter
A2cp1_3308	ENOG4107QWP	ABC-2 type transporter
A2cp1_3309	ENOG4107QWP	ABC-2 type transporter
A2cp1_3310	ENOG4108303	d-xylulose 5-phosphate d-fructose 6-phosphate phosphoketolase
A2cp1_3311	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
A2cp1_3312	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A2cp1_3314	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
A2cp1_3319	ENOG4105GRZ	Ycii-related protein
A2cp1_3323	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
A2cp1_3324	ENOG4108KPJ	rna polymerase sigma factor
A2cp1_3325	ENOG4105EJC	lysr family transcriptional regulator
A2cp1_3326	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
A2cp1_3327	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
A2cp1_3328	ENOG4105BZU	Histidine kinase
A2cp1_3330	ENOG4108IND	Tetr family transcriptional regulator
A2cp1_3331	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
A2cp1_3337	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
A2cp1_3343	ENOG4105D63	family UPF0324
A2cp1_3357	ENOG4105DQ4	alcohol dehydrogenase
A2cp1_3360	ENOG4105CJ1	ABC, transporter
A2cp1_3361	ENOG4105EEQ	Na H antiporter
A2cp1_3362	ENOG4105EQ2	LysR family Transcriptional regulator
A2cp1_3364	ENOG4107R84	Peptidase dimerisation domain
A2cp1_3366	ENOG4105VEQ	Cold shock protein
A2cp1_3368	ENOG4107TTQ	Alpha beta hydrolase fold
A2cp1_3372	ENOG4108IJ8	ABC transporter
A2cp1_3373	ENOG4105E90	ABC transporter
A2cp1_3375	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
A2cp1_3376	ENOG4105BZU	Histidine kinase
A2cp1_3377	ENOG4105BZU	Histidine kinase
A2cp1_3379	ENOG4105E2V	Glycosyltransferase 36
A2cp1_3385	ENOG4105CHR	reductase
A2cp1_3389	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
A2cp1_3391	ENOG4105BZP	glycoside hydrolase 15-related
A2cp1_3392	ENOG4105KJJ	Uncharacterized ACR, COG1993
A2cp1_3397	ENOG4105CF7	AraC family transcriptional regulator
A2cp1_3398	ENOG4105ENX	hydrolase
A2cp1_3403	ENOG4108KPJ	rna polymerase sigma factor
A2cp1_3406	ENOG4107RAQ	aminopeptidase
A2cp1_3412	ENOG4105CE1	Ferrous iron transport protein b
A2cp1_3414	ENOG4105FRY	Dehydrogenase
A2cp1_3439	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
A2cp1_3440	ENOG4107STQ	Multicopper oxidase
A2cp1_3442	ENOG4105C6T	cysteine synthase
A2cp1_3447	ENOG4108V0P	LemA family
A2cp1_3448	ENOG4105D0M	Protease HtpX homolog
A2cp1_3457	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
A2cp1_3476	ENOG4105CUV	Homoserine Kinase
A2cp1_3482	ENOG4105KCK	Peptidoglycan-associated lipoprotein
A2cp1_3483	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_3484	ENOG4108JQC	penicillin-binding protein 1A
A2cp1_3487	ENOG4105ES5	Histidine kinase
A2cp1_3490	ENOG4105C7N	Xanthine uracil vitamin C permease
A2cp1_3491	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
A2cp1_3493	ENOG4107YX5	Pfam:DUF548
A2cp1_3496	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A2cp1_3497	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
A2cp1_3498	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
A2cp1_3500	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
A2cp1_3502	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
A2cp1_3504	ENOG4105CKK	Glycosyl transferase, family 2
A2cp1_3506	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
A2cp1_3508	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
A2cp1_3512	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
A2cp1_3514	ENOG4105CZX	twitching motility protein
A2cp1_3516	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
A2cp1_3518	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
A2cp1_3520	ENOG4105C4R	Atp-dependent dna helicase
A2cp1_3526	ENOG4105C34	Pseudouridine synthase
A2cp1_3528	ENOG4107RAN	Peptidase, M16
A2cp1_3530	ENOG4105BZU	Histidine kinase
A2cp1_3532	ENOG4105C2J	ABC transporter
A2cp1_3533	ENOG4105DR5	peptidase
A2cp1_3534	ENOG4105ECY	inositol monophosphatase
A2cp1_3537	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A2cp1_3540	ENOG4105DFU	Cell wall formation (By similarity)
A2cp1_3542	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
A2cp1_3543	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
A2cp1_3544	ENOG4105C02	permease
A2cp1_3545	ENOG4108V1T	peptidylprolyl cis-trans isomerase
A2cp1_3558	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
A2cp1_3559	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A2cp1_3560	ENOG4105D60	lipoprotein releasing system transmembrane protein
A2cp1_3561	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
A2cp1_3563	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
A2cp1_3567	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
A2cp1_3571	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
A2cp1_3576	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
A2cp1_3577	ENOG4105CM2	brancheD-chain amino acid aminotransferase
A2cp1_3578	ENOG41090HR	transcriptional regulator
A2cp1_3582	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
A2cp1_3590	ENOG4105NBK	UPF0345 protein
A2cp1_3593	ENOG4105C0B	DNA polymerase III (alpha subunit)
A2cp1_3596	ENOG4108S01	response regulator
A2cp1_3597	ENOG4105C7B	Threonine dehydratase
A2cp1_3606	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
A2cp1_3608	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
A2cp1_3613	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
A2cp1_3615	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
A2cp1_3616	ENOG4105EHG	Permease protein
A2cp1_3617	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
A2cp1_3620	ENOG4105SVQ	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression (By similarity)
A2cp1_3621	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
A2cp1_3624	ENOG4105BZU	Histidine kinase
A2cp1_3625	ENOG4105BZU	Histidine kinase
A2cp1_3628	ENOG4108WBT	adenosyltransferase
A2cp1_3630	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
A2cp1_3631	ENOG4105C5X	domain protein
A2cp1_3632	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
A2cp1_3634	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
A2cp1_3639	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
A2cp1_3640	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
A2cp1_3641	ENOG4105EUB	pirin domain protein
A2cp1_3648	ENOG4105VPX	protein, conserved in bacteria
A2cp1_3652	ENOG4105VPX	protein, conserved in bacteria
A2cp1_3653	ENOG4105C59	p-type ATPase
A2cp1_3656	ENOG4105CHP	RNA polymerase
A2cp1_3657	ENOG4105GRZ	Ycii-related protein
A2cp1_3661	ENOG4105E2K	Glycosyl transferase (Group 1
A2cp1_3663	ENOG4105CPC	Aldo Keto reductase
A2cp1_3664	ENOG4105HEI	LysR family (Transcriptional regulator
A2cp1_3665	ENOG4105K63	Thioredoxin
A2cp1_3671	ENOG4105C8Q	Methyl-accepting chemotaxis
A2cp1_3672	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
A2cp1_3677	ENOG4107QJZ	Glycosyl transferase, family 2
A2cp1_3678	ENOG4107RIZ	hflk protein
A2cp1_3679	ENOG4105EPW	hflc protein
A2cp1_3684	ENOG4107EFR	Flavocytochrome c
A2cp1_3685	ENOG4108M3P	Membrane
A2cp1_3701	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
A2cp1_3703	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
A2cp1_3705	ENOG4105E4C	Lytic transglycosylase catalytic
A2cp1_3706	ENOG4108IYU	L-aspartate oxidase
A2cp1_3708	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
A2cp1_3712	ENOG4108EUD	Lysophospholipase
A2cp1_3718	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
A2cp1_3721	ENOG41072GX	Peptidase M22 Glycoprotease
A2cp1_3722	ENOG4105DZP	Membrane-associated zinc metalloprotease
A2cp1_3724	ENOG4105KNE	Phosphatidate cytidylyltransferase
A2cp1_3725	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
A2cp1_3726	ENOG4108PBA	serine threonine protein kinase
A2cp1_3729	ENOG4105CFH	Aspartokinase
A2cp1_3734	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
A2cp1_3735	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
A2cp1_3740	ENOG4108D1K	outer membrane usher protein
A2cp1_3744	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
A2cp1_3745	ENOG4107RDT	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
A2cp1_3750	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
A2cp1_3751	ENOG4108ZAI	phosphatidylglycerophosphatase a
A2cp1_3756	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
A2cp1_3774	ENOG4105CXV	gliding motility protein
A2cp1_3776	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
A2cp1_3778	ENOG4105C6E	dna polymerase iii
A2cp1_3779	ENOG4108Z6B	deaminase
A2cp1_3782	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A2cp1_3786	ENOG4105UYK	outer membrane protein a
A2cp1_3787	ENOG4105Y3U	Transglycosylase-associated protein
A2cp1_3790	ENOG4107QPV	Serine Threonine protein kinase
A2cp1_3794	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
A2cp1_3795	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A2cp1_3796	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A2cp1_3799	ENOG4108JPZ	Monovalent cation H antiporter subunit D
A2cp1_3800	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A2cp1_3801	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
A2cp1_3805	ENOG4105DAP	Nicotinate phosphoribosyltransferase
A2cp1_3806	ENOG4107QM5	aconitate hydratase
A2cp1_3812	ENOG4105DR5	peptidase
A2cp1_3814	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
A2cp1_3822	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
A2cp1_3829	ENOG4105BZU	Histidine kinase
A2cp1_3830	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A2cp1_3832	ENOG4108ZF3	Phosphatase
A2cp1_3833	ENOG4108S0S	Nucleotidyl transferase
A2cp1_3835	ENOG4105DH5	Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (By similarity)
A2cp1_3837	ENOG4107QN1	sodium solute
A2cp1_3839	ENOG4105CSH	Transporter
A2cp1_3843	ENOG4107QN1	sodium solute
A2cp1_3844	ENOG4105C8Q	Methyl-accepting chemotaxis
A2cp1_3847	ENOG4105C28	cystathionine
A2cp1_3850	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
A2cp1_3858	ENOG4105C8Q	Methyl-accepting chemotaxis
A2cp1_3859	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
A2cp1_3860	ENOG4105DSQ	Nitric oxide reductase
A2cp1_3861	ENOG4105C8F	Beta-lactamase domain protein
A2cp1_3862	ENOG4105DR4	Methyltransferase
A2cp1_3864	ENOG41062D9	Histidine kinase
A2cp1_3867	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
A2cp1_3869	ENOG4105BZU	Histidine kinase
A2cp1_3870	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_3871	ENOG4105C4M	(Ubiquinol oxidase) subunit I
A2cp1_3872	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
A2cp1_3874	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
A2cp1_3876	ENOG4105EMN	RNA polymerase sigma factor
A2cp1_3881	ENOG4108SPH	protein kinase (EC 2.7.11.1)
A2cp1_3883	ENOG4105E39	Enoyl-CoA hydratase
A2cp1_3884	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
A2cp1_3888	ENOG4105UYK	outer membrane protein a
A2cp1_3889	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A2cp1_3891	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
A2cp1_3895	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
A2cp1_3896	ENOG4108MG3	formate dehydrogenase
A2cp1_3897	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
A2cp1_3900	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
A2cp1_3905	ENOG4105CJN	penicillin-binding protein
A2cp1_3906	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
A2cp1_3907	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
A2cp1_3909	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
A2cp1_3917	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
A2cp1_3918	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
A2cp1_3921	ENOG4105MHT	Transcriptional regulator, ARSR family
A2cp1_3925	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A2cp1_3928	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
A2cp1_3933	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
A2cp1_3934	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_3939	ENOG4105CN1	protease
A2cp1_3942	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
A2cp1_3949	ENOG41090R7	Ferric uptake
A2cp1_3950	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
A2cp1_3951	ENOG4108UUM	single-stranded DNA-binding protein
A2cp1_3956	ENOG4105MHT	Transcriptional regulator, ARSR family
A2cp1_3958	ENOG4105CIZ	coA-substrate-specific enzyme activase
A2cp1_3960	ENOG4108Q5F	Tetr family transcriptional regulator
A2cp1_3965	ENOG4105W5Q	DNA repair protein (RadC
A2cp1_3966	ENOG4105DZW	Dipeptidase
A2cp1_3967	ENOG4108YYC	ycei family
A2cp1_3969	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
A2cp1_3970	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
A2cp1_3971	ENOG4105CHM	Aminotransferase
A2cp1_3976	ENOG4108Q9H	CobQ/CobB/MinD/ParA nucleotide binding domain
A2cp1_3980	ENOG4105C37	(CBS) domain
A2cp1_3981	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
A2cp1_3982	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
A2cp1_3986	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
A2cp1_3987	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
A2cp1_3988	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
A2cp1_3990	ENOG4105EMU	Dehydrogenase
A2cp1_3996	ENOG41062D9	Histidine kinase
A2cp1_3997	ENOG4108RQS	Two component transcriptional regulator (Winged helix family
A2cp1_4005	ENOG4105CMM	transposase
A2cp1_4011	ENOG4105CFI	type iii restriction protein res subunit
A2cp1_4018	ENOG4108KPJ	rna polymerase sigma factor
A2cp1_4019	ENOG4107QRT	dEAD DEAH box helicase
A2cp1_4021	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
A2cp1_4023	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
A2cp1_4030	ENOG4105EPH	radical SAM domain protein
A2cp1_4036	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
A2cp1_4039	ENOG4105C8Q	Methyl-accepting chemotaxis
A2cp1_4042	ENOG4108JA1	polyketide synthase
A2cp1_4044	ENOG4105D29	Helix-turn-helix type 11 domain protein
A2cp1_4048	ENOG4105DTA	methyltransferase
A2cp1_4051	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
A2cp1_4057	ENOG4105C5H	ABC transporter
A2cp1_4060	ENOG4105D25	secreted protein
A2cp1_4063	ENOG4105D2S	major facilitator superfamily
A2cp1_4064	ENOG4107QSV	RmuC domain protein
A2cp1_4068	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
A2cp1_4070	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
A2cp1_4071	ENOG4105C6K	Malic enzyme
A2cp1_4075	ENOG4105CEP	NADH dehydrogenase
A2cp1_4081	ENOG4105C19	ABC transporter
A2cp1_4083	ENOG4108DG9	Smr protein MutS2
A2cp1_4086	ENOG4105BZS	acriflavin resistance protein
A2cp1_4087	ENOG4105CJW	magnesium transporter
A2cp1_4092	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
A2cp1_4093	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A2cp1_4094	ENOG4105C3M	thioredoxin reductase
A2cp1_4095	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
A2cp1_4097	ENOG4105BZU	Histidine kinase
A2cp1_4100	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
A2cp1_4102	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
A2cp1_4103	ENOG4105M7V	2'-5' rna ligase
A2cp1_4108	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
A2cp1_4112	ENOG4105D1Z	hydroxypyruvate reductase
A2cp1_4119	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
A2cp1_4124	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
A2cp1_4126	ENOG4105HFZ	Membrane
A2cp1_4128	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
A2cp1_4130	ENOG4105C5H	ABC transporter
A2cp1_4131	ENOG4105F27	Major Facilitator
A2cp1_4137	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
A2cp1_4141	ENOG4108R5S	membrane
A2cp1_4144	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
A2cp1_4145	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
A2cp1_4146	ENOG4105E2Z	phosphate ABC transporter (Permease
A2cp1_4147	ENOG4105C8U	phosphate abc transporter
A2cp1_4148	ENOG4105CVA	phosphate
A2cp1_4150	ENOG4105BZU	Histidine kinase
A2cp1_4153	ENOG4105BZU	Histidine kinase
A2cp1_4154	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
A2cp1_4159	ENOG4105D94	Major Facilitator Superfamily
A2cp1_4163	ENOG4105DUX	Transporter
A2cp1_4164	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
A2cp1_4165	ENOG4105M08	Membrane
A2cp1_4166	ENOG41083V2	Pterin carbinolamine dehydratase
A2cp1_4168	ENOG4107RN3	metallophosphoesterase
A2cp1_4171	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
A2cp1_4176	ENOG4105SG9	biopolymer transport protein, ExbD
A2cp1_4177	ENOG4105E02	MotA TolQ exbB proton channel
A2cp1_4181	ENOG410900P	UPF0336 protein
A2cp1_4183	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
A2cp1_4186	ENOG4105CJN	penicillin-binding protein
A2cp1_4187	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
A2cp1_4188	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
A2cp1_4189	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
A2cp1_4192	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
A2cp1_4195	ENOG4105CRQ	synthase (Component I)
A2cp1_4196	ENOG4105DDQ	anthranilate synthase
A2cp1_4198	ENOG4105DK0	Indole-3-glycerol phosphate synthase
A2cp1_4199	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
A2cp1_4200	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
A2cp1_4201	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
A2cp1_4203	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
A2cp1_4209	ENOG4108ZT1	Transcriptional regulator
A2cp1_4210	ENOG4108KTG	Membrane protein, drug metabolite transporter
A2cp1_4212	ENOG4105C2X	Arabinose 5-phosphate isomerase
A2cp1_4214	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
A2cp1_4215	ENOG4105ERH	Fumarylacetoacetate hydrolase
A2cp1_4218	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
A2cp1_4223	ENOG4108ZVT	methylmalonyl-coA epimerase
A2cp1_4225	ENOG4108JIC	nucleoside recognition domain protein
A2cp1_4235	ENOG4107QPH	glycogen) synthase
A2cp1_4245	ENOG4105CPK	Glycosyl transferase (Group 1
A2cp1_4246	ENOG4108V5V	Serine Threonine protein kinase
A2cp1_4247	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
A2cp1_4249	ENOG4105F0N	pyrophosphate phospho-hydrolase
A2cp1_4253	ENOG4105CIH	Imidazole acetol-phosphate transaminase
A2cp1_4255	ENOG4108IJF	Heavy metal efflux pump, CzcA
A2cp1_4269	ENOG4105BZU	Histidine kinase
A2cp1_4272	ENOG4105C1G	acyl-Coa dehydrogenase
A2cp1_4275	ENOG4105BZU	Histidine kinase
A2cp1_4276	ENOG4105BZU	Histidine kinase
A2cp1_4280	ENOG4105CG3	alpha amylase, catalytic region
A2cp1_4287	ENOG4105DRW	binding-protein-dependent transport systems inner membrane Component
A2cp1_4290	ENOG4108IJ9	(ABC) transporter
A2cp1_4291	ENOG4107T9C	Alpha amylase catalytic region
A2cp1_4300	ENOG4105E2K	Glycosyl transferase (Group 1
A2cp1_4308	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A2cp1_4309	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A2cp1_4310	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
A2cp1_4311	ENOG4105C3F	Signal peptidase i
A2cp1_4318	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
A2cp1_4320	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
A2cp1_4321	ENOG4108IUZ	ABC transporter
A2cp1_4324	ENOG4105D1S	lipid A biosynthesis
A2cp1_4325	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
A2cp1_4326	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
A2cp1_4329	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A2cp1_4330	ENOG4105C34	Pseudouridine synthase
A2cp1_4332	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
A2cp1_4345	ENOG4105EJG	cellulose synthase
A2cp1_4346	ENOG4105CNU	cell division protein FtsK
A2cp1_4347	ENOG4108WHA	ompa motb domain protein
A2cp1_4353	ENOG4107YX3	NADH dehydrogenase subunit j
A2cp1_4356	ENOG4107R88	Chemotaxis protein (CheV)
A2cp1_4357	ENOG41082BV	acetyltransferase
A2cp1_4361	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
A2cp1_4362	ENOG4107R72	Ceramidase
A2cp1_4368	ENOG4105BZU	Histidine kinase
A2cp1_4375	ENOG4105C98	muts2 protein
A2cp1_4376	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
A2cp1_4382	ENOG4105BZU	Histidine kinase
A2cp1_4384	ENOG4107QXV	Phosphate transporter
A2cp1_4385	ENOG4108QEV	ribosomal RNA large subunit methyltransferase N
A2cp1_4392	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
A2cp1_4396	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_4398	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
A2cp1_4402	ENOG4105BZU	Histidine kinase
A2cp1_4404	ENOG4108YZA	Nitrogen regulatory protein pii
A2cp1_4406	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
A2cp1_4409	ENOG4105KPY	Small multidrug resistance protein
A2cp1_4412	ENOG4108IV0	ABC, transporter
A2cp1_4413	ENOG4105C0Z	ABC transporter
A2cp1_4414	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
A2cp1_4415	ENOG4105C32	Amino acid ABC transporter (Permease)
A2cp1_4417	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
A2cp1_4420	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
A2cp1_4423	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
A2cp1_4426	ENOG4105EMN	RNA polymerase sigma factor
A2cp1_4430	ENOG4105DAY	polysaccharide export protein
A2cp1_4434	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
A2cp1_4438	ENOG4108KMV	Glycosyl transferase (Group 1
A2cp1_4439	ENOG4107RJ7	Glycosyl transferase (Group 1
A2cp1_4441	ENOG4105DDI	hemolysin-type calcium-binding region
A2cp1_4444	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
A2cp1_4448	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
A2cp1_4451	ENOG4107QQG	Dehydrogenase
A2cp1_4453	ENOG4105CKK	Glycosyl transferase, family 2
A2cp1_4456	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
A2cp1_4460	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
A2cp1_4461	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
A2cp1_4462	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
A2cp1_4467	ENOG4105BZU	Histidine kinase
A2cp1_4468	ENOG4105C8M	UPF0272 protein
A2cp1_4469	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
A2cp1_4471	ENOG4105CBS	Chea signal transduction histidine kinase
A2cp1_4472	ENOG4107YTP	response regulator receiver protein
A2cp1_4473	ENOG4108ZGA	chew protein
A2cp1_4474	ENOG4105C8Q	Methyl-accepting chemotaxis
A2cp1_4475	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
A2cp1_4476	ENOG4105BZU	Histidine kinase
A2cp1_4477	ENOG4105CXV	gliding motility protein
A2cp1_4478	ENOG4105DVT	helicase
A2cp1_4482	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
A2cp1_4483	ENOG4105CFG	Acts as a chaperone (By similarity)
A2cp1_4484	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
A2cp1_4487	ENOG4108JA2	transcriptioN-repair coupling factor
A2cp1_4490	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
A2cp1_4491	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
A2cp1_4492	ENOG4105C3G	gtp-binding protein
A2cp1_4501	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
A2cp1_4503	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
A2cp1_4507	ENOG4105VN1	Heat shock protein
A2cp1_4509	ENOG4105FA0	parb-like partition protein
A2cp1_4510	ENOG4107QJE	Chromosome Partitioning Protein
A2cp1_4516	ENOG41084M4	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)