locus-tag	class	description
AMPC_00050	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMPC_00100	COG0741	lytic transglycosylase activity
AMPC_00120	COG2267	carboxylic ester hydrolase activity
AMPC_00150	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AMPC_00160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMPC_00160	COG2205	protein histidine kinase activity
AMPC_00210	COG0737	Belongs to the 5'-nucleotidase family
AMPC_00260	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AMPC_00270	COG0416	fatty acid biosynthetic process
AMPC_00290	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AMPC_00310	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AMPC_00320	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AMPC_00330	COG4771	TonB-dependent receptor
AMPC_00350	COG0840	transmembrane signaling receptor activity
AMPC_00360	COG0698	ribose 5-phosphate isomerase
AMPC_00370	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AMPC_00380	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AMPC_00410	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMPC_00410	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AMPC_00420	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AMPC_00450	COG0784	Response regulator, receiver
AMPC_00450	COG0643	Histidine kinase
AMPC_00450	COG2198	Histidine kinase
AMPC_00450	COG2198	Histidine kinase
AMPC_00450	COG0643	Histidine kinase
AMPC_00450	COG0784	Response regulator, receiver
AMPC_00460	COG3267	Type II secretory pathway component ExeA
AMPC_00460	COG3409	Peptidoglycan-binding domain 1 protein
AMPC_00480	COG0835	chemotaxis
AMPC_00500	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AMPC_00510	COG2201	protein-glutamate methylesterase activity
AMPC_00520	COG0745	RESPONSE REGULATOR receiver
AMPC_00530	COG0708	Exodeoxyribonuclease III
AMPC_00560	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AMPC_00570	COG0616	signal peptide processing
AMPC_00580	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AMPC_00590	COG1607	acyl-coa hydrolase
AMPC_00660	COG1408	metallophosphoesterase
AMPC_00670	COG1396	sequence-specific DNA binding
AMPC_00800	COG0318	PFAM AMP-dependent synthetase and ligase
AMPC_00810	COG3875	lactate racemase activity
AMPC_00850	COG1280	lysine exporter protein (LysE YggA)
AMPC_00860	COG0243	molybdopterin cofactor binding
AMPC_00870	COG1049	propionate catabolic process, 2-methylcitrate cycle
AMPC_00900	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AMPC_00920	COG0022	dehydrogenase e1 component
AMPC_00940	COG0114	fumarate hydratase activity
AMPC_01170	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AMPC_01200	COG0443	Heat shock 70 kDa protein
AMPC_01210	COG0484	heat shock protein binding
AMPC_01230	COG1335	isochorismatase
AMPC_01240	COG0010	Belongs to the arginase family
AMPC_01250	COG1899	peptidyl-lysine modification to peptidyl-hypusine
AMPC_01260	COG0613	PHP domain protein
AMPC_01270	COG1959	2 iron, 2 sulfur cluster binding
AMPC_01280	COG1007	ATP synthesis coupled electron transport
AMPC_01300	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AMPC_01310	COG0713	ATP synthesis coupled electron transport
AMPC_01330	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMPC_01340	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AMPC_01350	COG0649	NAD binding
AMPC_01360	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMPC_01370	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMPC_01380	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMPC_01410	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMPC_01420	COG0649	NAD binding
AMPC_01430	COG1034	ATP synthesis coupled electron transport
AMPC_01440	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AMPC_01450	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMPC_01480	COG0456	acetyltransferase
AMPC_01500	COG0010	Belongs to the arginase family
AMPC_01520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AMPC_01550	COG2223	nitrite transmembrane transporter activity
AMPC_01560	COG1796	DNA polymerase
AMPC_01560	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AMPC_01570	COG0521	Mo-molybdopterin cofactor biosynthetic process
AMPC_01620	COG0277	FAD linked oxidase domain protein
AMPC_01630	COG0247	lactate metabolic process
AMPC_01640	COG1139	Iron-sulfur cluster binding protein
AMPC_01680	COG1509	lysine 2,3-aminomutase activity
AMPC_01700	COG0586	Pfam SNARE associated Golgi protein
AMPC_01710	COG2385	sporulation resulting in formation of a cellular spore
AMPC_01720	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AMPC_01730	COG0343	queuine tRNA-ribosyltransferase activity
AMPC_01740	COG1862	Preprotein translocase
AMPC_01750	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMPC_01760	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AMPC_01770	COG1064	alcohol dehydrogenase
AMPC_01810	COG1136	(ABC) transporter
AMPC_01810	COG0577	efflux transmembrane transporter activity
AMPC_01830	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AMPC_01860	COG0463	Glycosyl transferase, family 2
AMPC_01860	COG0457	Tetratricopeptide repeat
AMPC_01870	COG0463	Glycosyl transferase, family 2
AMPC_01870	COG0457	Tetratricopeptide repeat
AMPC_01880	COG0457	Tetratricopeptide repeat
AMPC_01880	COG0463	Glycosyl transferase, family 2
AMPC_01890	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AMPC_01940	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMPC_01950	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AMPC_01970	COG0438	transferase activity, transferring glycosyl groups
AMPC_01980	COG1216	Glycosyl transferase, family 2
AMPC_02020	COG1028	Short-chain dehydrogenase reductase Sdr
AMPC_02030	COG0318	PFAM AMP-dependent synthetase and ligase
AMPC_02110	COG4191	Histidine kinase
AMPC_02120	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AMPC_02140	COG2022	thiamine diphosphate biosynthetic process
AMPC_02160	COG0352	thiamine-phosphate diphosphorylase activity
AMPC_02210	COG1074	ATP-dependent DNA helicase activity
AMPC_02230	COG1830	Aldolase
AMPC_02240	COG1045	serine acetyltransferase
AMPC_02330	COG0424	maF-like protein
AMPC_02340	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMPC_02370	COG0768	penicillin binding
AMPC_02380	COG0772	Belongs to the SEDS family
AMPC_02390	COG3118	belongs to the thioredoxin family
AMPC_02400	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMPC_02410	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AMPC_02420	COG0181	hydroxymethylbilane synthase activity
AMPC_02450	COG0585	pseudouridine synthase activity
AMPC_02520	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AMPC_02540	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AMPC_02540	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMPC_02550	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AMPC_02590	COG5434	Belongs to the glycosyl hydrolase 28 family
AMPC_02630	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMPC_02640	COG0138	bifunctional purine biosynthesis protein purh
AMPC_02650	COG0745	RESPONSE REGULATOR receiver
AMPC_02720	COG1216	Glycosyl transferase, family 2
AMPC_02740	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AMPC_02750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMPC_02770	COG0438	transferase activity, transferring glycosyl groups
AMPC_02780	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AMPC_02800	COG0028	Belongs to the TPP enzyme family
AMPC_02860	COG0028	Belongs to the TPP enzyme family
AMPC_02870	COG0463	Glycosyl transferase, family 2
AMPC_02910	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AMPC_02920	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AMPC_02940	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AMPC_02970	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMPC_02980	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
AMPC_03050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AMPC_03080	COG0113	porphobilinogen synthase activity
AMPC_03110	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMPC_03160	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AMPC_03190	COG0303	'Molybdopterin
AMPC_03200	COG0557	exoribonuclease II activity
AMPC_03220	COG2885	chlorophyll binding
AMPC_03230	COG0730	response to heat
AMPC_03300	COG1193	negative regulation of DNA recombination
AMPC_03310	COG1301	dicarboxylic acid transport
AMPC_03330	COG0438	transferase activity, transferring glycosyl groups
AMPC_03350	COG3876	Protein conserved in bacteria
AMPC_03380	COG0542	response to heat
AMPC_03400	COG0459	protein refolding
AMPC_03410	COG1028	Short-chain dehydrogenase reductase Sdr
AMPC_03420	COG1309	transcriptional regulator
AMPC_03430	COG3706	GGDEF domain
AMPC_03460	COG0525	valine-tRNA ligase activity
AMPC_03480	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AMPC_03480	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AMPC_03490	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AMPC_03580	COG1595	DNA-templated transcription, initiation
AMPC_03620	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AMPC_03640	COG1573	uracil-dna glycosylase
AMPC_03660	COG0330	HflC and HflK could
AMPC_03680	COG0183	Belongs to the thiolase family
AMPC_03690	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AMPC_03730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AMPC_03750	COG1119	ATPase activity
AMPC_03770	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMPC_03780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AMPC_03790	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMPC_03800	COG0586	Pfam SNARE associated Golgi protein
AMPC_03810	COG0443	Heat shock 70 kDa protein
AMPC_03820	COG0516	GMP reductase activity
AMPC_03820	COG0517	IMP dehydrogenase activity
AMPC_03830	COG0519	Catalyzes the synthesis of GMP from XMP
AMPC_03830	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AMPC_03890	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AMPC_03910	COG3746	phosphate-selective porin O and P
AMPC_03930	COG1121	(ABC) transporter
AMPC_03940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AMPC_03970	COG2860	membrane
AMPC_04010	COG2205	protein histidine kinase activity
AMPC_04130	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMPC_04170	COG0730	response to heat
AMPC_04200	COG0039	L-malate dehydrogenase activity
AMPC_04250	COG0137	argininosuccinate synthase activity
AMPC_04280	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMPC_04290	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMPC_04340	COG1346	cytolysis
AMPC_04350	COG1380	Effector of murein hydrolase LrgA
AMPC_04360	COG0583	DNA-binding transcription factor activity
AMPC_04400	COG0840	transmembrane signaling receptor activity
AMPC_04410	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AMPC_04430	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMPC_04450	COG1278	Cold shock
AMPC_04480	COG1966	Carbon starvation protein
AMPC_04490	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AMPC_04490	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AMPC_04510	COG0437	4 iron, 4 sulfur cluster binding
AMPC_04540	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AMPC_04550	COG2814	Major facilitator Superfamily
AMPC_04560	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AMPC_04610	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMPC_04650	COG1136	(ABC) transporter
AMPC_04660	COG0577	efflux transmembrane transporter activity
AMPC_04810	COG1333	cytochrome c biogenesis protein
AMPC_04810	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMPC_04830	COG0788	formyltetrahydrofolate deformylase activity
AMPC_04840	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AMPC_04850	COG0830	nickel cation binding
AMPC_04870	COG0831	urea catabolic process
AMPC_04870	COG0832	Belongs to the urease beta subunit family
AMPC_04880	COG0829	nickel cation binding
AMPC_04890	COG5002	protein histidine kinase activity
AMPC_04910	COG2204	response regulator
AMPC_04930	COG3064	Membrane
AMPC_04930	COG0437	4 iron, 4 sulfur cluster binding
AMPC_04940	COG5557	Pfam Polysulphide reductase, NrfD
AMPC_04950	COG0509	glycine decarboxylation via glycine cleavage system
AMPC_04970	COG0509	glycine decarboxylation via glycine cleavage system
AMPC_05000	COG0501	Belongs to the peptidase M48B family
AMPC_05030	COG2197	response regulator
AMPC_05120	COG1333	cytochrome c biogenesis protein
AMPC_05120	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMPC_05140	COG1032	radical SAM domain protein
AMPC_05290	COG4191	Histidine kinase
AMPC_05300	COG2204	response regulator
AMPC_05320	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMPC_05340	COG0745	RESPONSE REGULATOR receiver
AMPC_05350	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AMPC_05370	COG1217	gtp-binding protein TYPA
AMPC_05390	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMPC_05420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMPC_05430	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMPC_05470	COG0535	radical SAM domain protein
AMPC_05490	COG1228	amidohydrolase
AMPC_05530	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AMPC_05540	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMPC_05550	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AMPC_05570	COG0473	3-isopropylmalate dehydrogenase activity
AMPC_05610	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AMPC_05630	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AMPC_05640	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AMPC_05650	COG0072	phenylalanine-tRNA ligase activity
AMPC_05680	COG2204	response regulator
AMPC_05690	COG2205	protein histidine kinase activity
AMPC_05720	COG0302	gtp cyclohydrolase
AMPC_05730	COG1028	Short-chain dehydrogenase reductase Sdr
AMPC_05740	COG0277	FAD linked oxidase domain protein
AMPC_05760	COG1013	pyruvate-flavodoxin oxidoreductase activity
AMPC_05770	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AMPC_05770	COG0674	pyruvate-flavodoxin oxidoreductase activity
AMPC_05790	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AMPC_05790	COG0674	pyruvate-flavodoxin oxidoreductase activity
AMPC_05800	COG1013	pyruvate-flavodoxin oxidoreductase activity
AMPC_05890	COG2264	protein methyltransferase activity
AMPC_05900	COG1132	(ABC) transporter
AMPC_05920	COG0438	transferase activity, transferring glycosyl groups
AMPC_05930	COG0673	inositol 2-dehydrogenase activity
AMPC_05940	COG1063	alcohol dehydrogenase
AMPC_05950	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMPC_06020	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMPC_06060	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AMPC_06070	COG0049	tRNA binding
AMPC_06080	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AMPC_06090	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AMPC_06100	COG0051	transcription antitermination factor activity, RNA binding
AMPC_06110	COG0088	Forms part of the polypeptide exit tunnel
AMPC_06120	COG0089	rRNA binding
AMPC_06170	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AMPC_06180	COG0255	Belongs to the universal ribosomal protein uL29 family
AMPC_06210	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AMPC_06220	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AMPC_06230	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AMPC_06240	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AMPC_06250	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AMPC_06260	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AMPC_06270	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AMPC_06290	COG0200	Binds to the 23S rRNA
AMPC_06300	COG0201	protein transport
AMPC_06310	COG0563	adenylate kinase activity
AMPC_06320	COG0024	Methionine aminopeptidase
AMPC_06330	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AMPC_06350	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AMPC_06370	COG0202	RNA polymerase activity
AMPC_06400	COG0228	four-way junction DNA binding
AMPC_06410	COG1837	Belongs to the UPF0109 family
AMPC_06420	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AMPC_06430	COG0336	Belongs to the RNA methyltransferase TrmD family
AMPC_06440	COG0335	large ribosomal subunit rRNA binding
AMPC_06460	COG0792	nuclease activity
AMPC_06480	COG2204	response regulator
AMPC_06490	COG3852	Histidine kinase
AMPC_06550	COG2226	methyltransferase
AMPC_06570	COG1166	arginine decarboxylase activity
AMPC_06660	COG1970	mechanosensitive ion channel activity
AMPC_06670	COG3360	Dodecin
AMPC_06680	COG2233	PERMEase
AMPC_06790	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AMPC_06800	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AMPC_06810	COG1127	ABC transporter
AMPC_06830	COG0577	efflux transmembrane transporter activity
AMPC_06830	COG1136	(ABC) transporter
AMPC_06840	COG1136	(ABC) transporter
AMPC_06840	COG0577	efflux transmembrane transporter activity
AMPC_06860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMPC_06890	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AMPC_06890	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AMPC_06900	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AMPC_06900	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AMPC_06920	COG1024	Enoyl-CoA hydratase
AMPC_06930	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMPC_06940	COG1960	acyl-CoA dehydrogenase activity
AMPC_06970	COG0571	ribonuclease III activity
AMPC_07000	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AMPC_07010	COG1160	GTP binding
AMPC_07090	COG4221	oxidoreductase activity
AMPC_07360	COG1960	acyl-CoA dehydrogenase activity
AMPC_07370	COG1024	Enoyl-CoA hydratase
AMPC_07380	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMPC_07410	COG0489	protein tyrosine kinase activity
AMPC_07420	COG0430	RNA-3'-phosphate cyclase activity
AMPC_07470	COG1187	pseudouridine synthase activity
AMPC_07480	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AMPC_07490	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AMPC_07500	COG0180	Tryptophanyl-tRNA synthetase
AMPC_07510	COG1994	Peptidase M50
AMPC_07520	COG4974	Belongs to the 'phage' integrase family
AMPC_07530	COG0009	L-threonylcarbamoyladenylate synthase
AMPC_07560	COG0189	ligase activity
AMPC_07570	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
AMPC_07580	COG0860	N-Acetylmuramoyl-L-alanine amidase
AMPC_07600	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AMPC_07620	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AMPC_07650	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AMPC_07670	COG0515	serine threonine protein kinase
AMPC_07670	COG2815	serine threonine protein kinase
AMPC_07730	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AMPC_07750	COG0166	Belongs to the GPI family
AMPC_07800	COG1058	Belongs to the CinA family
AMPC_07800	COG1546	Belongs to the CinA family
AMPC_07810	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AMPC_07850	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AMPC_07860	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AMPC_07880	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AMPC_07900	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AMPC_07910	COG0742	ribosomal rna small subunit methyltransferase
AMPC_07930	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMPC_07960	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AMPC_07960	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AMPC_08000	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AMPC_08010	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMPC_08020	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AMPC_08050	COG0494	nUDIX hydrolase
AMPC_08060	COG0646	methionine synthase
AMPC_08060	COG1410	methionine synthase
AMPC_08100	COG0443	Heat shock 70 kDa protein
AMPC_08110	COG0210	DNA helicase
AMPC_08160	COG1555	photosystem II stabilization
AMPC_08170	COG0527	aspartate kinase activity
AMPC_08190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AMPC_08220	COG0022	dehydrogenase e1 component
AMPC_08230	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AMPC_08240	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AMPC_08270	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AMPC_08280	COG0148	phosphopyruvate hydratase activity
AMPC_08290	COG1028	Short-chain dehydrogenase reductase Sdr
AMPC_08320	COG1494	fructose-1,6-bisphosphatase
AMPC_08400	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AMPC_08430	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AMPC_08450	COG0039	L-malate dehydrogenase activity
AMPC_08460	COG0538	isocitrate dehydrogenase activity
AMPC_08480	COG4191	Histidine kinase
AMPC_08500	COG0505	Belongs to the CarA family
AMPC_08530	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AMPC_08560	COG0481	GTPase activity
AMPC_08570	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AMPC_08630	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMPC_08670	COG0741	lytic transglycosylase activity
AMPC_08690	COG0204	Acyl-transferase
AMPC_08760	COG0085	RNA polymerase activity
AMPC_08770	COG0222	ribosome binding
AMPC_08780	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AMPC_08790	COG0081	regulation of translation
AMPC_08840	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AMPC_08850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMPC_08870	COG0189	ligase activity
AMPC_08880	COG0443	Heat shock 70 kDa protein
AMPC_08910	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AMPC_08920	COG3706	GGDEF domain
AMPC_09090	COG2204	response regulator
AMPC_09110	COG2843	Capsule synthesis protein
AMPC_09150	COG0443	Heat shock 70 kDa protein
AMPC_09190	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AMPC_09210	COG0101	tRNA pseudouridine synthase activity
AMPC_09250	COG0529	Catalyzes the synthesis of activated sulfate
AMPC_09250	COG2046	Belongs to the sulfate adenylyltransferase family
AMPC_09280	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AMPC_09310	COG0443	Heat shock 70 kDa protein
AMPC_09360	COG0149	triose-phosphate isomerase activity
AMPC_09370	COG0126	phosphoglycerate kinase activity
AMPC_09380	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AMPC_09400	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AMPC_09430	COG0018	arginyl-trna synthetase
AMPC_09460	COG0616	signal peptide processing
AMPC_09480	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AMPC_09500	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AMPC_09510	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMPC_09520	COG0825	malonyl-CoA metabolic process
AMPC_09530	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AMPC_09590	COG0802	atpase or kinase
AMPC_09600	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AMPC_09600	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AMPC_09620	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AMPC_09630	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AMPC_09650	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AMPC_09660	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AMPC_09670	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMPC_09680	COG0037	tRNA processing
AMPC_09710	COG1278	Cold shock
AMPC_09720	COG0004	ammonium transporteR
AMPC_09750	COG0776	regulation of translation
AMPC_09760	COG3246	L-lysine catabolic process to acetate
AMPC_09770	COG1607	acyl-coa hydrolase
AMPC_09780	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AMPC_09800	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AMPC_09810	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMPC_09820	COG0482	sulfurtransferase activity
AMPC_09830	COG5002	protein histidine kinase activity
AMPC_09900	COG0745	RESPONSE REGULATOR receiver
AMPC_09980	COG2855	membrane
AMPC_10040	COG0745	RESPONSE REGULATOR receiver
AMPC_10070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMPC_10110	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMPC_10170	COG1028	Short-chain dehydrogenase reductase Sdr
AMPC_10190	COG0437	4 iron, 4 sulfur cluster binding
AMPC_10210	COG0667	Aldo Keto reductase
AMPC_10270	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AMPC_10290	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AMPC_10290	COG4651	solute:proton antiporter activity
AMPC_10330	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AMPC_10340	COG0513	Belongs to the DEAD box helicase family
AMPC_10360	COG0429	hydrolase of the alpha beta-hydrolase fold
AMPC_10370	COG0328	RNA-DNA hybrid ribonuclease activity
AMPC_10400	COG0038	chloride channel
AMPC_10420	COG0308	aminopeptidase N
AMPC_10430	COG0419	ATPase involved in DNA repair
AMPC_10460	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AMPC_10500	COG0596	Alpha beta hydrolase
AMPC_10510	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AMPC_10540	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AMPC_10560	COG0298	carbon dioxide binding
AMPC_10580	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AMPC_10730	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMPC_10770	COG2204	response regulator
AMPC_10800	COG1677	Flagellar hook-basal body complex protein FliE
AMPC_10820	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AMPC_10900	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AMPC_10930	COG0835	chemotaxis
AMPC_10940	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AMPC_10960	COG3279	Response regulator of the LytR AlgR family
AMPC_10980	COG2201	protein-glutamate methylesterase activity
AMPC_10990	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AMPC_11010	COG0745	RESPONSE REGULATOR receiver
AMPC_11070	COG1338	Plays a role in the flagellum-specific transport system
AMPC_11080	COG1987	bacterial-type flagellum assembly
AMPC_11090	COG1684	flagellar biosynthetic protein fliR
AMPC_11100	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMPC_11110	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMPC_11120	COG1419	protein localization to endoplasmic reticulum
AMPC_11150	COG0463	Glycosyl transferase, family 2
AMPC_11150	COG0457	Tetratricopeptide repeat
AMPC_11170	COG4786	Flagellar basal body rod
AMPC_11180	COG4786	Flagellar basal body rod
AMPC_11200	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
AMPC_11250	COG1256	bacterial-type flagellum assembly
AMPC_11250	COG4786	Flagellar basal body rod
AMPC_11280	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AMPC_11340	COG1763	Mo-molybdopterin cofactor biosynthetic process
AMPC_11350	COG0303	'Molybdopterin
AMPC_11370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMPC_11400	COG2205	protein histidine kinase activity
AMPC_11410	COG4566	intracellular signal transduction
AMPC_11410	COG0745	RESPONSE REGULATOR receiver
AMPC_11420	COG3852	Histidine kinase
AMPC_11470	COG3481	metal-dependent phosphohydrolase, HD sub domain
AMPC_11490	COG0084	hydrolase, TatD family'
AMPC_11500	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMPC_11500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AMPC_11530	COG0784	Response regulator, receiver
AMPC_11530	COG2205	protein histidine kinase activity
AMPC_11590	COG0752	glycyl-tRNA synthetase alpha subunit
AMPC_11650	COG0602	queuosine metabolic process
AMPC_11710	COG0456	acetyltransferase
AMPC_11710	COG1214	PFAM Peptidase M22, glycoprotease
AMPC_11750	COG2937	Belongs to the GPAT DAPAT family
AMPC_11770	COG0483	inositol monophosphate 1-phosphatase activity
AMPC_11800	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMPC_11850	COG1045	serine acetyltransferase
AMPC_11910	COG0322	excinuclease ABC activity
AMPC_11940	COG0556	nucleotide-excision repair
AMPC_11960	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AMPC_11960	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AMPC_11970	COG1329	Transcriptional regulator
AMPC_11980	COG0658	competence protein
AMPC_11980	COG2333	competence protein COMEC
AMPC_12040	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AMPC_12050	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AMPC_12060	COG1309	transcriptional regulator
AMPC_12110	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AMPC_12120	COG1234	tRNA 3'-trailer cleavage
AMPC_12130	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AMPC_12140	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AMPC_12150	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AMPC_12160	COG1683	Conserved Protein
AMPC_12180	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AMPC_12190	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AMPC_12220	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AMPC_12240	COG1028	Short-chain dehydrogenase reductase Sdr
AMPC_12250	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AMPC_12270	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMPC_12280	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AMPC_12310	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AMPC_12330	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AMPC_12340	COG1278	Cold shock
AMPC_12390	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AMPC_12400	COG2766	serine protein kinase
AMPC_12410	COG2718	Belongs to the UPF0229 family
AMPC_12420	COG2719	SpoVR family
AMPC_12430	COG0739	heme binding
AMPC_12470	COG0840	transmembrane signaling receptor activity
AMPC_12510	COG1047	Peptidyl-prolyl cis-trans
AMPC_12540	COG3411	Ferredoxin
AMPC_12550	COG2912	Transglutaminase-like superfamily
AMPC_12610	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AMPC_12620	COG0194	GDP metabolic process
AMPC_12630	COG1561	YicC-like family, N-terminal region
AMPC_12640	COG2835	tetraacyldisaccharide 4'-kinase activity
AMPC_12650	COG0438	transferase activity, transferring glycosyl groups
AMPC_12670	COG0463	Glycosyl transferase, family 2
AMPC_12680	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AMPC_12680	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AMPC_12690	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AMPC_12690	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AMPC_12710	COG1663	tetraacyldisaccharide 4'-kinase activity
AMPC_12720	COG0859	PFAM glycosyl transferase family 9
AMPC_12730	COG1519	Transferase
AMPC_12750	COG1132	(ABC) transporter
AMPC_12770	COG2095	MarC family integral membrane protein
AMPC_12780	COG1216	Glycosyl transferase, family 2
AMPC_12790	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AMPC_12810	COG5002	protein histidine kinase activity
AMPC_12840	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AMPC_12860	COG1394	ATPase activity, coupled to movement of substances
AMPC_12880	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
AMPC_12930	COG1269	ATP hydrolysis coupled proton transport
AMPC_12970	COG1053	succinate dehydrogenase
AMPC_12990	COG0438	transferase activity, transferring glycosyl groups
AMPC_13070	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AMPC_13080	COG0489	protein tyrosine kinase activity
AMPC_13130	COG2204	response regulator
AMPC_13150	COG2385	sporulation resulting in formation of a cellular spore
AMPC_13290	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
AMPC_13440	COG1929	Belongs to the glycerate kinase type-1 family
AMPC_13450	COG1620	l-lactate permease
AMPC_13480	COG1028	Short-chain dehydrogenase reductase Sdr
AMPC_13490	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AMPC_13500	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AMPC_13560	COG0237	dephospho-CoA kinase activity
AMPC_13610	COG0443	Heat shock 70 kDa protein
AMPC_13630	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AMPC_13650	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AMPC_13660	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
AMPC_13690	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
AMPC_13740	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AMPC_13750	COG0758	DNA mediated transformation
AMPC_13750	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMPC_13760	COG1652	LysM domain
AMPC_13790	COG1196	nuclear chromosome segregation
AMPC_13790	COG0745	RESPONSE REGULATOR receiver
AMPC_13860	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
AMPC_13880	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AMPC_13890	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
AMPC_13900	COG1480	7TM receptor with intracellular HD hydrolase
AMPC_13910	COG1702	phosphate starvation-inducible protein PhoH
AMPC_13940	COG3956	TIGRFAM MazG family protein
AMPC_13950	COG0268	Binds directly to 16S ribosomal RNA
AMPC_13970	COG0495	leucyl-tRNA aminoacylation
AMPC_13980	COG0017	Asparaginyl-tRNA synthetase
AMPC_14020	COG1324	tolerance protein
AMPC_14090	COG1592	Rubrerythrin
AMPC_14110	COG1051	belongs to the nudix hydrolase family
AMPC_14130	COG0750	zinc metalloprotease
AMPC_14150	COG0314	molybdopterin synthase activity
AMPC_14160	COG0745	RESPONSE REGULATOR receiver
AMPC_14170	COG2199	diguanylate cyclase activity
AMPC_14170	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AMPC_14180	COG0546	phosphoglycolate phosphatase activity
AMPC_14200	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMPC_14220	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AMPC_14250	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AMPC_14270	COG1185	polyribonucleotide nucleotidyltransferase activity
AMPC_14280	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AMPC_14300	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AMPC_14380	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AMPC_14390	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AMPC_14400	COG0745	RESPONSE REGULATOR receiver
AMPC_14410	COG1722	exodeoxyribonuclease VII activity
AMPC_14420	COG1570	exodeoxyribonuclease VII activity
AMPC_14440	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AMPC_14450	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMPC_14460	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AMPC_14480	COG3494	Protein of unknown function (DUF1009)
AMPC_14530	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AMPC_14540	COG1136	(ABC) transporter
AMPC_14570	COG1543	Belongs to the glycosyl hydrolase 57 family
AMPC_14610	COG5000	phosphorelay sensor kinase activity
AMPC_14630	COG4221	oxidoreductase activity
AMPC_14640	COG0457	Tetratricopeptide repeat
AMPC_14650	COG3405	Belongs to the glycosyl hydrolase 8 (cellulase D) family
AMPC_14660	COG1215	transferase activity, transferring glycosyl groups
AMPC_14670	COG1215	transferase activity, transferring glycosyl groups
AMPC_14700	COG2204	response regulator
AMPC_14740	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AMPC_14750	COG0531	amino acid
AMPC_14790	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AMPC_14830	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
AMPC_14840	COG1692	metallophosphoesterase
AMPC_14860	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AMPC_14880	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AMPC_14900	COG1335	isochorismatase
AMPC_15020	COG2132	Multicopper oxidase
AMPC_15030	COG0604	alcohol dehydrogenase
AMPC_15050	COG0745	RESPONSE REGULATOR receiver
AMPC_15060	COG0745	RESPONSE REGULATOR receiver
AMPC_15080	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMPC_15090	COG3387	PFAM Glycoside hydrolase 15-related
AMPC_15180	COG3285	dna ligase
AMPC_15180	COG1793	dna ligase
AMPC_15220	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AMPC_15240	COG2255	four-way junction helicase activity
AMPC_15270	COG2205	protein histidine kinase activity
AMPC_15280	COG2814	Major facilitator Superfamily
AMPC_15290	COG0534	Mate efflux family protein
AMPC_15330	COG1331	Highly conserved protein containing a thioredoxin domain
AMPC_15350	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMPC_15370	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AMPC_15380	COG0583	DNA-binding transcription factor activity
AMPC_15430	COG1192	Involved in chromosome partitioning
AMPC_15470	COG0432	Pfam Uncharacterised protein family UPF0047
AMPC_15500	COG2873	o-acetylhomoserine
AMPC_15540	COG0529	Catalyzes the synthesis of activated sulfate
AMPC_15550	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMPC_15550	COG1648	precorrin-2 dehydrogenase activity
AMPC_15560	COG1648	precorrin-2 dehydrogenase activity
AMPC_15560	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AMPC_15580	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
AMPC_15590	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AMPC_15600	COG4208	sulfate ABC transporter
AMPC_15610	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AMPC_15620	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMPC_15630	COG5002	protein histidine kinase activity
AMPC_15640	COG2204	response regulator
AMPC_15650	COG3005	denitrification pathway
AMPC_15660	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AMPC_15680	COG0243	molybdopterin cofactor binding
AMPC_15710	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
AMPC_15720	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AMPC_15740	COG0658	competence protein
AMPC_15740	COG2333	competence protein COMEC
AMPC_15800	COG0109	protoheme IX farnesyltransferase activity
AMPC_15810	COG1131	(ABC) transporter
AMPC_15830	COG2322	membrane
AMPC_15840	COG1999	signal sequence binding
AMPC_15860	COG0668	transmembrane transport
AMPC_15870	COG0840	transmembrane signaling receptor activity
AMPC_15880	COG0840	transmembrane signaling receptor activity
AMPC_16050	COG4964	Belongs to the GSP D family
AMPC_16140	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AMPC_16180	COG2814	Major facilitator Superfamily
AMPC_16210	COG0437	4 iron, 4 sulfur cluster binding
AMPC_16210	COG3064	Membrane
AMPC_16230	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AMPC_16250	COG1596	polysaccharide export
AMPC_16280	COG0438	transferase activity, transferring glycosyl groups
AMPC_16340	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMPC_16350	COG0367	asparagine synthase
AMPC_16380	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AMPC_16390	COG1086	Polysaccharide biosynthesis protein
AMPC_16400	COG0489	protein tyrosine kinase activity
AMPC_16400	COG3206	protein involved in exopolysaccharide biosynthesis
AMPC_16460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AMPC_16500	COG0667	Aldo Keto reductase
AMPC_16530	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AMPC_16540	COG0697	spore germination
AMPC_16570	COG1271	oxidase subunit
AMPC_16580	COG1294	oxidase, subunit
AMPC_16590	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AMPC_16610	COG0765	amino acid transport
AMPC_16620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMPC_16650	COG2202	Pas domain
AMPC_16650	COG2205	protein histidine kinase activity
AMPC_16700	COG1917	Cupin 2, conserved barrel domain protein
AMPC_16710	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AMPC_16750	COG0798	PFAM Bile acid sodium symporter
AMPC_16760	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AMPC_16790	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AMPC_16930	COG1204	response to ionizing radiation
AMPC_17020	COG0305	Participates in initiation and elongation during chromosome replication
AMPC_17050	COG1074	ATP-dependent DNA helicase activity
AMPC_17110	COG1397	ADP-ribosylglycohydrolase
AMPC_17180	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AMPC_17240	COG0514	ATP-dependent DNA helicase (RecQ)
AMPC_17340	COG1469	GTP cyclohydrolase I activity
AMPC_17350	COG0720	synthase
AMPC_17360	COG0602	queuosine metabolic process
AMPC_17610	COG1475	DNA binding
AMPC_17620	COG2003	Belongs to the UPF0758 family
AMPC_17690	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AMPC_17700	COG1475	DNA binding
AMPC_17770	COG4974	Belongs to the 'phage' integrase family
AMPC_17810	COG0006	proline dipeptidase activity
AMPC_17840	COG0604	alcohol dehydrogenase
AMPC_17890	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AMPC_17900	COG1355	regulation of microtubule-based process
AMPC_18070	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMPC_18100	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AMPC_18120	COG2204	response regulator
AMPC_18140	COG2885	chlorophyll binding
AMPC_18200	COG0584	glycerophosphoryl diester phosphodiesterase
AMPC_18240	COG2814	Major facilitator Superfamily
AMPC_18250	COG0318	PFAM AMP-dependent synthetase and ligase
AMPC_18280	COG0348	domain, Protein
AMPC_18290	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AMPC_18300	COG0840	transmembrane signaling receptor activity
AMPC_18310	COG0438	transferase activity, transferring glycosyl groups
AMPC_18370	COG0513	Belongs to the DEAD box helicase family
AMPC_18410	COG0277	FAD linked oxidase domain protein
AMPC_18420	COG0277	FAD linked oxidase domain protein
AMPC_18430	COG0247	lactate metabolic process
AMPC_18440	COG1620	l-lactate permease
AMPC_18480	COG1028	Short-chain dehydrogenase reductase Sdr
AMPC_18580	COG0546	phosphoglycolate phosphatase activity
AMPC_18610	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMPC_18630	COG2860	membrane
AMPC_18650	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AMPC_18670	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AMPC_18680	COG2205	protein histidine kinase activity
AMPC_18690	COG0745	RESPONSE REGULATOR receiver
AMPC_18700	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AMPC_18740	COG0693	protein deglycase activity
AMPC_18760	COG0784	Response regulator, receiver
AMPC_18760	COG2205	protein histidine kinase activity
AMPC_18770	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AMPC_18790	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AMPC_18820	COG0628	permease
AMPC_18840	COG1960	acyl-CoA dehydrogenase activity
AMPC_18860	COG0653	protein targeting
AMPC_18870	COG0739	heme binding
AMPC_18880	COG0631	protein serine/threonine phosphatase activity
AMPC_18890	COG0497	DNA recombination
AMPC_18900	COG2205	protein histidine kinase activity
AMPC_18920	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AMPC_18930	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AMPC_19050	COG0316	Belongs to the HesB IscA family
AMPC_19060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMPC_19070	COG1012	belongs to the aldehyde dehydrogenase family
AMPC_19080	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AMPC_19100	COG0746	molybdenum cofactor guanylyltransferase activity
AMPC_19130	COG2201	protein-glutamate methylesterase activity
AMPC_19150	COG0840	transmembrane signaling receptor activity
AMPC_19190	COG3259	Nickel-dependent hydrogenase
AMPC_19210	COG1034	ATP synthesis coupled electron transport
AMPC_19240	COG2205	protein histidine kinase activity
AMPC_19240	COG4191	Histidine kinase
AMPC_19240	COG0745	RESPONSE REGULATOR receiver
AMPC_19280	COG4191	Histidine kinase
AMPC_19340	COG4191	Histidine kinase
AMPC_19440	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AMPC_19520	COG2205	protein histidine kinase activity
AMPC_19520	COG3437	response regulator, receiver
AMPC_19520	COG3850	Histidine kinase
AMPC_19520	COG4999	Histidine kinase
AMPC_19530	COG4932	domain protein
AMPC_19530	COG5492	domain, Protein
AMPC_19540	COG1064	alcohol dehydrogenase
AMPC_19570	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMPC_19570	COG1333	cytochrome c biogenesis protein
AMPC_19600	COG1333	cytochrome c biogenesis protein
AMPC_19600	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMPC_19680	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMPC_19680	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AMPC_19720	COG0739	heme binding
AMPC_19720	COG0741	lytic transglycosylase activity
AMPC_19720	COG1196	nuclear chromosome segregation
AMPC_19730	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AMPC_19750	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AMPC_19830	COG5002	protein histidine kinase activity
AMPC_19840	COG2205	protein histidine kinase activity
AMPC_19860	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AMPC_19880	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AMPC_19940	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AMPC_19970	COG1090	epimerase
AMPC_20000	COG0750	zinc metalloprotease
AMPC_20020	COG4589	Belongs to the CDS family
AMPC_20030	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AMPC_20060	COG1484	DNA-dependent DNA replication
AMPC_20080	COG0318	PFAM AMP-dependent synthetase and ligase
AMPC_20100	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AMPC_20120	COG0842	Transport permease protein
AMPC_20120	COG1129	ABC transporter
AMPC_20200	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AMPC_20210	COG0459	protein refolding
AMPC_20250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMPC_20270	COG2204	response regulator
AMPC_20280	COG2205	protein histidine kinase activity
AMPC_20310	COG3034	peptidoglycan biosynthetic process
AMPC_20340	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMPC_20400	COG1610	YqeY-like protein
AMPC_20410	COG0828	Belongs to the bacterial ribosomal protein bS21 family
AMPC_20430	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AMPC_20440	COG0107	imidazoleglycerol-phosphate synthase activity
AMPC_20450	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AMPC_20460	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AMPC_20470	COG0131	Imidazoleglycerol-phosphate dehydratase
AMPC_20480	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AMPC_20490	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AMPC_20620	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AMPC_20630	COG4789	Type iii secretion
AMPC_20640	COG0776	regulation of translation
AMPC_20650	COG1295	ribonuclease BN
AMPC_20660	COG1530	ribonuclease E activity
AMPC_20660	COG1530	ribonuclease E activity
AMPC_20700	COG0142	geranyltranstransferase activity
AMPC_20760	COG1657	PFAM Prenyltransferase squalene oxidase
AMPC_20770	COG1562	ergosterol biosynthetic process
AMPC_20780	COG3573	Dehydrogenase
AMPC_20790	COG1304	FMN binding
AMPC_20810	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMPC_20820	COG0784	Response regulator, receiver
AMPC_20820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMPC_20820	COG2205	protein histidine kinase activity
AMPC_20820	COG2198	Histidine kinase
AMPC_20830	COG1254	Belongs to the acylphosphatase family
AMPC_20840	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AMPC_20870	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AMPC_20880	COG0254	rRNA binding
AMPC_20900	COG2204	response regulator
AMPC_20930	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMPC_20950	COG2165	general secretion pathway protein
AMPC_21030	COG0596	Alpha beta hydrolase
AMPC_21030	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMPC_21050	COG1196	nuclear chromosome segregation
AMPC_21090	COG0552	protein localization to endoplasmic reticulum
AMPC_21100	COG1283	sodium-dependent phosphate transmembrane transporter activity
AMPC_21130	COG1215	transferase activity, transferring glycosyl groups
AMPC_21140	COG0793	Belongs to the peptidase S41A family
AMPC_21160	COG2177	Part of the ABC transporter FtsEX involved in
AMPC_21170	COG2884	Cell division ATP-binding protein ftsE
AMPC_21190	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AMPC_21300	COG3267	Type II secretory pathway component ExeA
AMPC_21300	COG3409	Peptidoglycan-binding domain 1 protein
AMPC_21320	COG0439	Biotin carboxylase
AMPC_21340	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AMPC_21420	COG2204	response regulator
AMPC_21430	COG4191	Histidine kinase
AMPC_21440	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AMPC_21450	COG1131	(ABC) transporter
AMPC_21460	COG4968	Prepilin-type N-terminal cleavage methylation domain
AMPC_21570	COG4191	Histidine kinase
AMPC_21580	COG1459	type II secretion system
AMPC_21600	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMPC_21610	COG0196	riboflavin kinase activity
AMPC_21620	COG0295	cytidine deaminase activity
AMPC_21630	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AMPC_21650	COG0217	transcriptional regulatory protein
AMPC_21670	COG2975	iron-sulfur cluster assembly
AMPC_21690	COG0443	Heat shock 70 kDa protein
AMPC_21710	COG0316	Belongs to the HesB IscA family
AMPC_21720	COG0822	iron-sulfur transferase activity
AMPC_21730	COG1104	cysteine desulfurase activity
AMPC_21740	COG4232	protein-disulfide reductase activity
AMPC_21780	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AMPC_21790	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AMPC_21860	COG2084	Dehydrogenase
AMPC_21880	COG2378	regulation of single-species biofilm formation
AMPC_21900	COG4493	Belongs to the UPF0637 family
AMPC_21920	COG5002	protein histidine kinase activity
AMPC_21930	COG0612	Peptidase, M16
AMPC_21990	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AMPC_22180	COG0288	reversible hydration of carbon dioxide
AMPC_22190	COG0835	chemotaxis
AMPC_22200	COG2201	protein-glutamate methylesterase activity
AMPC_22220	COG0840	transmembrane signaling receptor activity
AMPC_22240	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AMPC_22260	COG0745	RESPONSE REGULATOR receiver
AMPC_22310	COG0475	glutathione-regulated potassium exporter activity
AMPC_22360	COG0733	neurotransmitter:sodium symporter activity
AMPC_22370	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AMPC_22390	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMPC_22420	COG2211	Major facilitator Superfamily
AMPC_22430	COG2353	YceI-like domain
AMPC_22440	COG0217	transcriptional regulatory protein
AMPC_22450	COG5492	domain, Protein
AMPC_22450	COG4932	domain protein
AMPC_22500	COG1760	l-serine dehydratase
AMPC_22530	COG2855	membrane
AMPC_22550	COG0437	4 iron, 4 sulfur cluster binding
AMPC_22590	COG2989	Protein conserved in bacteria
AMPC_22640	COG0730	response to heat
AMPC_22660	COG2070	2-Nitropropane dioxygenase
AMPC_22720	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AMPC_22730	COG0437	4 iron, 4 sulfur cluster binding
AMPC_22740	COG5557	Pfam Polysulphide reductase, NrfD
AMPC_22750	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AMPC_22760	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AMPC_22770	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AMPC_22780	COG0298	carbon dioxide binding
AMPC_22810	COG0375	protein maturation
AMPC_22880	COG1252	NADH dehydrogenase
AMPC_22900	COG0154	amidase activity
AMPC_23000	COG1136	(ABC) transporter
AMPC_23000	COG0577	efflux transmembrane transporter activity
AMPC_23020	COG1136	(ABC) transporter
AMPC_23040	COG2840	Smr protein MutS2
AMPC_23180	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AMPC_23190	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AMPC_23190	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AMPC_23210	COG0492	ferredoxin-NADP+ reductase activity
AMPC_23270	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AMPC_23750	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AMPC_23760	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AMPC_23830	COG2204	response regulator
AMPC_23850	COG4191	Histidine kinase
AMPC_23890	COG1506	peptidase
AMPC_23890	COG0823	Involved in the tonB-independent uptake of proteins
AMPC_23900	COG0359	binds to the 23S rRNA
AMPC_23910	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AMPC_23920	COG0360	Binds together with S18 to 16S ribosomal RNA
AMPC_23930	COG0193	aminoacyl-tRNA hydrolase activity
AMPC_23950	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AMPC_23960	COG2088	sporulation resulting in formation of a cellular spore
AMPC_23970	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AMPC_23980	COG1196	nuclear chromosome segregation
AMPC_23990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AMPC_24000	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AMPC_24010	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AMPC_24080	COG1085	galactose-1-phosphate uridylyltransferase
AMPC_24090	COG0297	glycogen (starch) synthase activity
AMPC_24110	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AMPC_24120	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AMPC_24130	COG1573	uracil-dna glycosylase
AMPC_24150	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AMPC_24160	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AMPC_24190	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AMPC_24190	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AMPC_24250	COG0488	(ABC) transporter
AMPC_24340	COG2205	protein histidine kinase activity
AMPC_24390	COG0704	Plays a role in the regulation of phosphate uptake
AMPC_24400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMPC_24410	COG0581	inorganic phosphate transmembrane transporter activity
AMPC_24420	COG0573	inorganic phosphate transmembrane transporter activity
AMPC_24430	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AMPC_24450	COG5002	protein histidine kinase activity
AMPC_24470	COG3706	GGDEF domain
AMPC_24480	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AMPC_24480	COG0116	Belongs to the methyltransferase superfamily
AMPC_24490	COG2132	Multicopper oxidase
AMPC_24510	COG4122	O-methyltransferase activity
AMPC_24570	COG3104	oligopeptide transport
AMPC_24590	COG2363	Small membrane protein
AMPC_24600	COG2154	pterin-4-alpha-carbinolamine dehydratase
AMPC_24610	COG1408	metallophosphoesterase
AMPC_24620	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AMPC_24630	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMPC_24650	COG0811	peptide transport
AMPC_24720	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMPC_24770	COG0768	penicillin binding
AMPC_24780	COG0574	Belongs to the PEP-utilizing enzyme family
AMPC_24780	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AMPC_24810	COG0482	sulfurtransferase activity
AMPC_24840	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AMPC_24840	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AMPC_24860	COG2608	mercury ion transmembrane transporter activity
AMPC_24910	COG1201	RNA secondary structure unwinding
AMPC_24960	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
AMPC_24970	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AMPC_24980	COG0512	Glutamine amidotransferase of anthranilate synthase
AMPC_24990	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AMPC_25000	COG0134	indole-3-glycerol-phosphate synthase activity
AMPC_25010	COG0135	phosphoribosylanthranilate isomerase activity
AMPC_25020	COG0133	tryptophan synthase activity
AMPC_25030	COG0159	tryptophan synthase activity
AMPC_25110	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
AMPC_25130	COG0235	Class ii aldolase
AMPC_25150	COG0179	Fumarylacetoacetate (FAA) hydrolase
AMPC_25160	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AMPC_25170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AMPC_25180	COG0019	diaminopimelate decarboxylase activity
AMPC_25250	COG1305	Transglutaminase-like
AMPC_25260	COG2715	membrane protein required for spore maturation
AMPC_25270	COG0700	Nucleoside recognition
AMPC_25330	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AMPC_25370	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AMPC_25380	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMPC_25380	COG2755	lipolytic protein G-D-S-L family
AMPC_25410	COG0438	transferase activity, transferring glycosyl groups
AMPC_25420	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AMPC_25450	COG0339	signal peptide processing
AMPC_25490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AMPC_25500	COG1640	4-alpha-glucanotransferase
AMPC_25520	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AMPC_25580	COG1959	2 iron, 2 sulfur cluster binding
AMPC_25580	COG1295	ribonuclease BN
AMPC_25590	COG1278	Cold shock
AMPC_25610	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
AMPC_25660	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMPC_25660	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AMPC_25670	COG2326	polyphosphate kinase activity
AMPC_25690	COG0233	cytoplasmic translational termination
AMPC_25700	COG0528	UMP kinase activity
AMPC_25710	COG0617	tRNA 3'-terminal CCA addition
AMPC_25720	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AMPC_25740	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AMPC_25740	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AMPC_25750	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AMPC_25850	COG0848	biopolymer transport protein
AMPC_25870	COG0205	6-phosphofructokinase activity
AMPC_25910	COG0484	heat shock protein binding
AMPC_25920	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AMPC_25920	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AMPC_25940	COG4770	biotin carboxylase activity
AMPC_25950	COG2205	protein histidine kinase activity
AMPC_26010	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AMPC_26030	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AMPC_26040	COG2264	protein methyltransferase activity
AMPC_26050	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AMPC_26100	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AMPC_26150	COG1803	Methylglyoxal synthase
AMPC_26170	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AMPC_26220	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AMPC_26240	COG1164	Oligoendopeptidase f
AMPC_26330	COG0674	pyruvate-flavodoxin oxidoreductase activity
AMPC_26330	COG1013	pyruvate-flavodoxin oxidoreductase activity
AMPC_26330	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AMPC_26350	COG0799	negative regulation of ribosome biogenesis
AMPC_26360	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AMPC_26370	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AMPC_26440	COG0076	glutamate decarboxylase activity
AMPC_26450	COG3123	guanosine phosphorylase activity
AMPC_26460	COG0697	spore germination
AMPC_26470	COG2205	protein histidine kinase activity
AMPC_26480	COG1297	OPT oligopeptide transporter protein
AMPC_26540	COG2205	protein histidine kinase activity
AMPC_26560	COG3875	lactate racemase activity
AMPC_26600	COG0564	pseudouridine synthase activity
AMPC_26610	COG1216	Glycosyl transferase, family 2
AMPC_26620	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AMPC_26630	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AMPC_26640	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AMPC_26650	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AMPC_26670	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AMPC_26700	COG0537	adenosine 5'-monophosphoramidase activity
AMPC_26710	COG1490	D-aminoacyl-tRNA deacylase activity
AMPC_26750	COG0509	glycine decarboxylation via glycine cleavage system
AMPC_26770	COG5002	protein histidine kinase activity
AMPC_26780	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AMPC_26790	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AMPC_26820	COG4191	Histidine kinase
AMPC_26940	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AMPC_26960	COG0729	surface antigen
AMPC_27040	COG1968	undecaprenyl-diphosphatase activity
AMPC_27050	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AMPC_27080	COG3716	PTS system mannose fructose sorbose family IID component
AMPC_27110	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMPC_27110	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AMPC_27120	COG1660	Displays ATPase and GTPase activities
AMPC_27130	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AMPC_27150	COG2204	response regulator
AMPC_27190	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
AMPC_27280	COG0612	Peptidase, M16
AMPC_27320	COG0714	Associated with various cellular activities
AMPC_27350	COG1595	DNA-templated transcription, initiation
AMPC_27390	COG2132	Multicopper oxidase
AMPC_27400	COG0545	Peptidyl-prolyl cis-trans isomerase
AMPC_27470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMPC_27530	COG0438	transferase activity, transferring glycosyl groups
AMPC_27540	COG0438	transferase activity, transferring glycosyl groups
AMPC_27580	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AMPC_27580	COG2755	lipolytic protein G-D-S-L family
AMPC_27620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AMPC_27640	COG0463	Glycosyl transferase, family 2
AMPC_27660	COG1216	Glycosyl transferase, family 2
AMPC_27680	COG1215	transferase activity, transferring glycosyl groups
AMPC_27790	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AMPC_27820	COG0811	peptide transport
AMPC_27850	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AMPC_27860	COG1691	(AIR) carboxylase
AMPC_27880	COG0643	Histidine kinase
AMPC_27880	COG2198	Histidine kinase
AMPC_27890	COG2201	protein-glutamate methylesterase activity
AMPC_27900	COG0835	chemotaxis
AMPC_27930	COG2202	Pas domain
AMPC_27930	COG2205	protein histidine kinase activity
AMPC_27940	COG1100	Small GTP-binding protein
AMPC_27950	COG4191	Histidine kinase
AMPC_27960	COG1199	ATP-dependent helicase activity
AMPC_27990	COG0484	heat shock protein binding
AMPC_28000	COG0443	Heat shock 70 kDa protein
AMPC_28010	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AMPC_28050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMPC_28060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AMPC_28070	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AMPC_28080	COG0012	GTP binding
AMPC_28100	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AMPC_28170	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AMPC_28180	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AMPC_28190	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AMPC_28210	COG0071	Belongs to the small heat shock protein (HSP20) family
AMPC_28230	COG1475	DNA binding
AMPC_28240	COG1192	Involved in chromosome partitioning
AMPC_28260	COG0357	Ribosomal RNA small subunit methyltransferase G
AMPC_28290	COG0706	membrane insertase activity
AMPC_28310	COG0594	ribonuclease P activity
AMPC_28330	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AMPC_28340	COG0592	DNA-directed DNA polymerase activity
AMPC_28350	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AMPC_28370	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AMPC_28400	COG0247	lactate metabolic process
AMPC_28400	COG2181	nitrate reductase activity
AMPC_28440	COG0189	ligase activity
AMPC_28450	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AMPC_28460	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AMPC_28470	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AMPC_28530	COG3426	butyrate kinase activity
AMPC_28550	COG2086	electron transfer activity
AMPC_28570	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMPC_28590	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AMPC_28590	COG1793	dna ligase
AMPC_28600	COG0564	pseudouridine synthase activity
AMPC_28630	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AMPC_28650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AMPC_28660	COG0805	protein transport
AMPC_28670	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AMPC_28680	COG0473	3-isopropylmalate dehydrogenase activity
AMPC_28700	COG0183	Belongs to the thiolase family
AMPC_28710	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AMPC_28740	COG1032	radical SAM domain protein
AMPC_28760	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AMPC_28820	COG0352	thiamine-phosphate diphosphorylase activity
AMPC_28830	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AMPC_28860	COG0305	Participates in initiation and elongation during chromosome replication
AMPC_28910	COG1410	methionine synthase
AMPC_28910	COG0646	methionine synthase
AMPC_28960	COG1295	ribonuclease BN
AMPC_29040	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMPC_29070	COG2032	superoxide dismutase activity
AMPC_29090	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
AMPC_29100	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AMPC_29110	COG0210	DNA helicase
AMPC_29130	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AMPC_29150	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AMPC_29160	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMPC_29170	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AMPC_29180	COG1472	Belongs to the glycosyl hydrolase 3 family
AMPC_29200	COG3135	benzoate transporter
AMPC_29210	COG2962	Rard protein
AMPC_29320	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AMPC_29340	COG0686	Belongs to the AlaDH PNT family
AMPC_29400	COG1012	belongs to the aldehyde dehydrogenase family
AMPC_29440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AMPC_29460	COG1301	dicarboxylic acid transport
AMPC_29490	COG1280	lysine exporter protein (LysE YggA)
AMPC_29500	COG0436	Aminotransferase
AMPC_29520	COG2011	ABC-type metal ion transport system permease component
AMPC_29530	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AMPC_29540	COG1126	abc transporter atp-binding protein
AMPC_29560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMPC_29590	COG0280	phosphate acetyltransferase
AMPC_29600	COG3426	butyrate kinase activity
AMPC_29620	COG0174	glutamine synthetase
AMPC_29640	COG1741	Belongs to the pirin family
AMPC_29690	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMPC_29730	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AMPC_29790	COG0306	phosphate transporter
AMPC_29830	COG1193	negative regulation of DNA recombination
AMPC_29880	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMPC_29920	COG0745	RESPONSE REGULATOR receiver
AMPC_29940	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AMPC_30010	COG0839	Belongs to the complex I subunit 6 family
AMPC_30020	COG0713	ATP synthesis coupled electron transport
AMPC_30050	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AMPC_30070	COG1132	(ABC) transporter
AMPC_30100	COG1674	ftsk spoiiie
AMPC_30150	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AMPC_30200	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AMPC_30210	COG0211	Belongs to the bacterial ribosomal protein bL27 family
AMPC_30230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AMPC_30250	COG0564	pseudouridine synthase activity
AMPC_30280	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AMPC_30290	COG0504	CTP synthase activity
AMPC_30300	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AMPC_30310	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AMPC_30380	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AMPC_30390	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AMPC_30390	COG0446	pyridine nucleotide-disulphide oxidoreductase
AMPC_30400	COG0425	Belongs to the sulfur carrier protein TusA family
AMPC_30420	COG3259	Nickel-dependent hydrogenase
AMPC_30450	COG0681	Belongs to the peptidase S26 family
AMPC_30460	COG1136	(ABC) transporter
AMPC_30460	COG0577	efflux transmembrane transporter activity
AMPC_30480	COG0577	efflux transmembrane transporter activity
AMPC_30480	COG1136	(ABC) transporter
AMPC_30520	COG2259	Doxx family
AMPC_30550	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
AMPC_30570	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AMPC_30610	COG0038	chloride channel
AMPC_30660	COG0492	ferredoxin-NADP+ reductase activity
AMPC_30700	COG1247	-acetyltransferase
AMPC_30750	COG2814	Major facilitator Superfamily
AMPC_30760	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AMPC_30770	COG5002	protein histidine kinase activity
AMPC_30790	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AMPC_30840	COG0754	glutathionylspermidine amidase activity
AMPC_30870	COG0864	Transcriptional regulator
AMPC_30880	COG1733	regulation of RNA biosynthetic process
AMPC_30890	COG0702	epimerase
AMPC_30900	COG1122	ATPase activity
AMPC_30920	COG0310	cobalt ion transport
AMPC_30940	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AMPC_30970	COG0488	(ABC) transporter
AMPC_31020	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
AMPC_31060	COG5002	protein histidine kinase activity
AMPC_31070	COG2205	protein histidine kinase activity
AMPC_31080	COG0745	RESPONSE REGULATOR receiver
AMPC_31140	COG0473	3-isopropylmalate dehydrogenase activity
AMPC_31190	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
AMPC_31220	COG0398	Pfam SNARE associated Golgi protein
AMPC_31240	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMPC_31250	COG1305	Transglutaminase-like
AMPC_31300	COG0443	Heat shock 70 kDa protein
AMPC_31310	COG1538	Outer membrane efflux protein
AMPC_31320	COG0577	efflux transmembrane transporter activity
AMPC_31320	COG1136	(ABC) transporter
AMPC_31330	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMPC_31340	COG3852	Histidine kinase
AMPC_31390	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMPC_31430	COG1032	radical SAM domain protein
AMPC_31440	COG2205	protein histidine kinase activity
AMPC_31440	COG2202	Pas domain
AMPC_31450	COG0363	glucosamine-6-phosphate deaminase activity
AMPC_31460	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AMPC_31470	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AMPC_31480	COG0667	Aldo Keto reductase
AMPC_31510	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMPC_31520	COG3214	Protein conserved in bacteria
AMPC_31550	COG2204	response regulator
AMPC_31560	COG2205	protein histidine kinase activity
AMPC_31590	COG2204	response regulator
AMPC_31600	COG4191	Histidine kinase
AMPC_31610	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMPC_31620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AMPC_31640	COG0519	Catalyzes the synthesis of GMP from XMP
AMPC_31670	COG0303	'Molybdopterin
AMPC_31680	COG1278	Cold shock
AMPC_31690	COG0545	Peptidyl-prolyl cis-trans isomerase
AMPC_31710	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AMPC_31720	COG2204	response regulator
AMPC_31730	COG4191	Histidine kinase
AMPC_31740	COG0500	methyltransferase
AMPC_31760	COG2414	aldehyde ferredoxin oxidoreductase
AMPC_31810	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AMPC_31900	COG0583	DNA-binding transcription factor activity
AMPC_31920	COG4221	oxidoreductase activity
AMPC_31930	COG0667	Aldo Keto reductase
AMPC_31940	COG0667	Aldo Keto reductase
AMPC_31950	COG1073	alpha beta
AMPC_32030	COG1203	CRISPR-associated helicase, Cas3
AMPC_32060	COG1857	crispr-associated protein
AMPC_32090	COG1518	maintenance of DNA repeat elements
AMPC_32100	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AMPC_32110	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AMPC_32130	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AMPC_32140	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AMPC_32150	COG2890	protein-(glutamine-N5) methyltransferase activity
AMPC_32160	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AMPC_32230	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMPC_32230	COG1024	Enoyl-CoA hydratase
AMPC_32240	COG0183	Belongs to the thiolase family
AMPC_32250	COG1960	acyl-CoA dehydrogenase activity
AMPC_32290	COG0402	S-adenosylhomocysteine deaminase activity
AMPC_32300	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AMPC_32310	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AMPC_32320	COG0163	prenyltransferase activity
AMPC_32330	COG2226	methyltransferase
AMPC_32340	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AMPC_32370	COG0840	transmembrane signaling receptor activity
AMPC_32400	COG0745	RESPONSE REGULATOR receiver
AMPC_32400	COG2205	protein histidine kinase activity
AMPC_32400	COG4191	Histidine kinase
AMPC_32420	COG4191	Histidine kinase
AMPC_32430	COG4191	Histidine kinase
AMPC_32440	COG0542	response to heat
AMPC_32490	COG0318	PFAM AMP-dependent synthetase and ligase
AMPC_32520	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AMPC_32590	COG1234	tRNA 3'-trailer cleavage
AMPC_32600	COG0626	cystathionine gamma-synthase activity
AMPC_32630	COG1131	(ABC) transporter
AMPC_32690	COG5002	protein histidine kinase activity
AMPC_32710	COG1921	L-seryl-tRNASec selenium transferase activity
AMPC_32720	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AMPC_32780	COG4191	Histidine kinase
AMPC_32800	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AMPC_32810	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AMPC_32830	COG1088	dTDP-glucose 4,6-dehydratase activity
AMPC_32850	COG5002	protein histidine kinase activity
AMPC_32880	COG0492	ferredoxin-NADP+ reductase activity
AMPC_32950	COG0531	amino acid
AMPC_32960	COG3047	cAMP biosynthetic process
AMPC_32960	COG2885	chlorophyll binding
AMPC_33000	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AMPC_33030	COG0154	amidase activity
AMPC_33040	COG0667	Aldo Keto reductase
AMPC_33100	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMPC_33110	COG0667	Aldo Keto reductase
AMPC_33120	COG2814	Major facilitator Superfamily
AMPC_33140	COG0439	Biotin carboxylase
AMPC_33200	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AMPC_33230	COG1131	(ABC) transporter
AMPC_33240	COG1794	racemase activity, acting on amino acids and derivatives
AMPC_33250	COG0488	(ABC) transporter
AMPC_33260	COG2084	Dehydrogenase
AMPC_33300	COG0840	transmembrane signaling receptor activity
AMPC_33320	COG0366	Alpha amylase catalytic
AMPC_33340	COG0668	transmembrane transport
AMPC_33450	COG0312	modulator of DNA gyrase
AMPC_33460	COG0312	modulator of DNA gyrase
AMPC_33510	COG1529	Aldehyde oxidase and xanthine dehydrogenase
AMPC_33510	COG2010	Cytochrome c
AMPC_33520	COG0047	phosphoribosylformylglycinamidine synthase activity
AMPC_33530	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AMPC_33560	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AMPC_33620	COG1192	Involved in chromosome partitioning
AMPC_33650	COG0436	Aminotransferase
AMPC_33700	COG2353	YceI-like domain
AMPC_33710	COG2003	Belongs to the UPF0758 family
AMPC_33730	COG0589	response to stress
AMPC_33820	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AMPC_33830	COG0793	Belongs to the peptidase S41A family
AMPC_33830	COG3409	Peptidoglycan-binding domain 1 protein
AMPC_33840	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AMPC_33910	COG0714	Associated with various cellular activities
AMPC_33960	COG2010	Cytochrome c
AMPC_34000	COG1136	(ABC) transporter
AMPC_34000	COG0577	efflux transmembrane transporter activity
AMPC_34020	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AMPC_34030	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AMPC_34050	COG2205	protein histidine kinase activity
AMPC_34060	COG1201	RNA secondary structure unwinding
AMPC_34070	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AMPC_34150	COG1181	Belongs to the D-alanine--D-alanine ligase family
AMPC_34160	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AMPC_34200	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AMPC_34210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AMPC_34220	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AMPC_34230	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AMPC_34260	COG0275	rRNA processing
AMPC_34290	COG0300	oxidoreductase activity
AMPC_34300	COG0840	transmembrane signaling receptor activity
AMPC_34320	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMPC_34340	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AMPC_34390	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AMPC_34400	COG1024	Enoyl-CoA hydratase
AMPC_34410	COG0515	serine threonine protein kinase
AMPC_34430	COG1584	GPR1 FUN34 yaaH family protein
AMPC_34450	COG2226	methyltransferase
AMPC_34470	COG1294	oxidase, subunit
AMPC_34480	COG1271	oxidase subunit
AMPC_34490	COG2204	response regulator
AMPC_34500	COG4191	Histidine kinase
AMPC_34540	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AMPC_34570	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AMPC_34580	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AMPC_34600	COG1902	pentaerythritol trinitrate reductase activity
AMPC_34620	COG0626	cystathionine gamma-synthase activity
AMPC_34670	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AMPC_34700	COG0515	serine threonine protein kinase
AMPC_34700	COG2815	serine threonine protein kinase
AMPC_34710	COG0477	Major facilitator Superfamily
AMPC_34720	COG2814	Major facilitator Superfamily
AMPC_34730	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AMPC_34740	COG1695	Transcriptional regulator
AMPC_34750	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMPC_34760	COG0456	acetyltransferase
AMPC_34790	COG0673	inositol 2-dehydrogenase activity
AMPC_34800	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
AMPC_34820	COG1213	nucleotidyl transferase
AMPC_34820	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AMPC_34930	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AMPC_34940	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AMPC_34960	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AMPC_34970	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AMPC_34980	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
AMPC_35090	COG0739	heme binding
AMPC_35120	COG0475	glutathione-regulated potassium exporter activity
AMPC_35130	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AMPC_35140	COG1063	alcohol dehydrogenase
AMPC_35180	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AMPC_35220	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AMPC_35230	COG3261	NADH dehydrogenase
AMPC_35230	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AMPC_35240	COG0651	ATP synthesis coupled electron transport
AMPC_35310	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AMPC_35310	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AMPC_35320	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AMPC_35340	COG0590	tRNA wobble adenosine to inosine editing
AMPC_35350	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AMPC_35370	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AMPC_35390	COG1100	Small GTP-binding protein
AMPC_35570	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AMPC_35580	COG1183	phosphatidylcholine synthase activity
AMPC_35590	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AMPC_35600	COG0242	peptide deformylase activity
AMPC_35610	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AMPC_35620	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AMPC_35640	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AMPC_35660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AMPC_35690	COG4206	TonB-dependent receptor
AMPC_35700	COG1555	photosystem II stabilization
AMPC_35730	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AMPC_35750	COG2197	response regulator
AMPC_35770	COG1126	abc transporter atp-binding protein
AMPC_35780	COG0765	amino acid transport
AMPC_35790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMPC_35810	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AMPC_35820	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AMPC_35830	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AMPC_35870	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AMPC_36100	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AMPC_36110	COG0745	RESPONSE REGULATOR receiver
AMPC_36120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMPC_36140	COG2264	protein methyltransferase activity
AMPC_36160	COG0508	dehydrogenase complex catalyzes the overall conversion of
AMPC_36190	COG1643	Atp-dependent helicase
AMPC_36230	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AMPC_36260	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AMPC_36270	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AMPC_36280	COG1595	DNA-templated transcription, initiation
AMPC_36300	COG0437	4 iron, 4 sulfur cluster binding
AMPC_36370	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AMPC_36420	COG0028	Belongs to the TPP enzyme family
AMPC_36440	COG0247	lactate metabolic process
AMPC_36440	COG0277	FAD linked oxidase domain protein
AMPC_36470	COG1793	dna ligase
AMPC_36480	COG0069	glutamate synthase activity
AMPC_36480	COG0070	glutamate synthase
AMPC_36480	COG0067	glutamate synthase
AMPC_36490	COG0493	'glutamate synthase
AMPC_36520	COG5002	protein histidine kinase activity
AMPC_36540	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AMPC_36560	COG0437	4 iron, 4 sulfur cluster binding
AMPC_36590	COG2116	formate transmembrane transporter activity
AMPC_36600	COG0488	(ABC) transporter
AMPC_36620	COG2204	response regulator
AMPC_36630	COG2205	protein histidine kinase activity
AMPC_36660	COG1131	(ABC) transporter
AMPC_36670	COG0842	Transport permease protein
AMPC_36670	COG1129	ABC transporter
AMPC_36680	COG0842	Transport permease protein
AMPC_36750	COG0156	8-amino-7-oxononanoate synthase activity
AMPC_36760	COG1063	alcohol dehydrogenase
AMPC_36770	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AMPC_36800	COG0628	permease
AMPC_36920	COG0625	glutathione transferase activity
AMPC_36930	COG0545	Peptidyl-prolyl cis-trans isomerase
AMPC_36940	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AMPC_36950	COG1619	proteins homologs of microcin C7 resistance protein MccF
AMPC_36960	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
AMPC_36970	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AMPC_37010	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AMPC_37080	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AMPC_37110	COG2137	regulation of response to DNA damage stimulus
AMPC_37120	COG1174	glycine betaine transport
AMPC_37130	COG0517	IMP dehydrogenase activity
AMPC_37130	COG1125	glycine betaine transport
AMPC_37150	COG0477	Major facilitator Superfamily
AMPC_37180	COG0709	Synthesizes selenophosphate from selenide and ATP
AMPC_37190	COG0860	N-Acetylmuramoyl-L-alanine amidase
AMPC_37200	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AMPC_37210	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AMPC_37230	COG0544	peptidyl-prolyl cis-trans isomerase activity
AMPC_37240	COG0740	serine-type endopeptidase activity
AMPC_37260	COG3119	arylsulfatase activity
AMPC_37280	COG2521	methyltransferase
AMPC_37280	COG2136	Putative SAM-dependent methyltransferase
AMPC_37300	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AMPC_37330	COG4603	Belongs to the binding-protein-dependent transport system permease family
AMPC_37340	COG1129	ABC transporter
AMPC_37350	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AMPC_37430	COG1131	(ABC) transporter
AMPC_37440	COG0842	Transport permease protein
AMPC_37490	COG0514	ATP-dependent DNA helicase (RecQ)
AMPC_37530	COG0719	Fe-S assembly protein
AMPC_37540	COG0396	ATPase activity
AMPC_37550	COG0719	Fe-S assembly protein
AMPC_37560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AMPC_37570	COG0822	iron-sulfur transferase activity
AMPC_37700	COG0058	SHG alpha-glucan phosphorylase activity
AMPC_37710	COG2205	protein histidine kinase activity
AMPC_37730	COG1704	LemA family
AMPC_37780	COG1395	domain, Protein
AMPC_37790	COG0531	amino acid
AMPC_37800	COG0004	ammonium transporteR
AMPC_37810	COG0515	serine threonine protein kinase
AMPC_37840	COG0625	glutathione transferase activity
AMPC_37860	COG0443	Heat shock 70 kDa protein
AMPC_37870	COG0443	Heat shock 70 kDa protein
AMPC_37880	COG0488	(ABC) transporter
AMPC_37890	COG3158	transport of potassium into the cell
AMPC_37900	COG0347	Belongs to the P(II) protein family
AMPC_37910	COG0004	ammonium transporteR
AMPC_37920	COG2204	response regulator
AMPC_37930	COG4191	Histidine kinase
AMPC_37940	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AMPC_37950	COG1960	acyl-CoA dehydrogenase activity
AMPC_38000	COG0277	FAD linked oxidase domain protein
AMPC_38010	COG0183	Belongs to the thiolase family
AMPC_38040	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AMPC_38040	COG0674	pyruvate-flavodoxin oxidoreductase activity
AMPC_38080	COG0457	Tetratricopeptide repeat
AMPC_38080	COG0705	Rhomboid family
AMPC_38130	COG0343	queuine tRNA-ribosyltransferase activity
AMPC_38170	COG0515	serine threonine protein kinase
AMPC_38180	COG0493	'glutamate synthase
AMPC_38180	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AMPC_38190	COG0667	Aldo Keto reductase
AMPC_38270	COG2264	protein methyltransferase activity
AMPC_38300	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AMPC_38320	COG2864	formate dehydrogenase
AMPC_38330	COG0437	4 iron, 4 sulfur cluster binding
AMPC_38360	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AMPC_38370	COG0390	transport system, permease component
AMPC_38400	COG0247	lactate metabolic process
AMPC_38440	COG4191	Histidine kinase
AMPC_38440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMPC_38460	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AMPC_38570	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
AMPC_38590	COG3604	Transcriptional regulator
AMPC_38640	COG0406	alpha-ribazole phosphatase activity
AMPC_38700	COG3608	succinylglutamate desuccinylase aspartoacylase
AMPC_38700	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AMPC_38720	COG1309	transcriptional regulator
AMPC_38730	COG1162	GTPase activity
AMPC_38740	COG1162	GTPase activity
AMPC_38820	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMPC_38850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AMPC_38860	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AMPC_38900	COG3384	dioxygenase
AMPC_38930	COG2353	YceI-like domain
AMPC_38970	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AMPC_39000	COG1191	sigma factor activity
AMPC_39040	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMPC_39050	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AMPC_39160	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AMPC_39190	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AMPC_39230	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AMPC_39250	COG1250	3-hydroxyacyl-CoA dehydrogenase
AMPC_39330	COG1858	cytochrome C peroxidase
AMPC_39450	COG2197	response regulator
AMPC_39460	COG2205	protein histidine kinase activity
AMPC_39530	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AMPC_39540	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AMPC_39550	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AMPC_39560	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AMPC_39580	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AMPC_39620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AMPC_39640	COG0463	Glycosyl transferase, family 2
AMPC_39680	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AMPC_39770	COG3033	Beta-eliminating lyase
AMPC_39810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AMPC_39810	COG4191	Histidine kinase
AMPC_39850	COG0745	RESPONSE REGULATOR receiver
AMPC_39860	COG0516	GMP reductase activity
AMPC_39860	COG0517	IMP dehydrogenase activity
AMPC_39870	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AMPC_39900	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AMPC_39900	COG0519	Catalyzes the synthesis of GMP from XMP
AMPC_39930	COG0443	Heat shock 70 kDa protein