locus-tag	class	description
Anae109_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Anae109_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Anae109_0003	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Anae109_0005	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Anae109_0008	ENOG4105CPT	Alpha beta hydrolase
Anae109_0009	ENOG4105DF6	Fe-S oxidoreductase
Anae109_0012	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
Anae109_0013	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Anae109_0014	ENOG4107TEJ	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
Anae109_0015	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Anae109_0027	ENOG4105BZU	Histidine kinase
Anae109_0031	ENOG4105C57	major facilitator superfamily
Anae109_0032	ENOG4105DTD	Dehydrogenase
Anae109_0035	ENOG4105CKF	membrane protein involved in aromatic hydrocarbon degradation
Anae109_0036	ENOG4105CK7	Sodium proline symporter
Anae109_0039	ENOG4105DZS	Phenylacetate-CoA ligase
Anae109_0041	ENOG4105DZS	Phenylacetate-CoA ligase
Anae109_0045	ENOG4105CKM	Branched-chain carboxylic acid kinase
Anae109_0049	ENOG4105BZJ	Electron transfer flavoprotein
Anae109_0050	ENOG4105C10	Electron transfer flavoprotein
Anae109_0051	ENOG41069FQ	Metallo-beta-lactamase superfamily
Anae109_0052	ENOG4105EE5	Membrane protein terC
Anae109_0054	ENOG4107QPH	glycogen) synthase
Anae109_0055	ENOG4105CA3	membrane-bound lytic murein transglycosylase
Anae109_0057	ENOG4107T0X	DNA ligase
Anae109_0059	ENOG4105C34	Pseudouridine synthase
Anae109_0060	ENOG4108JQC	penicillin-binding protein 1A
Anae109_0063	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Anae109_0064	ENOG4105CHU	acetyl-coa acetyltransferase
Anae109_0070	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
Anae109_0071	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
Anae109_0073	ENOG4105C0H	protease
Anae109_0075	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Anae109_0076	ENOG4108Z86	Glutamine amidotransferase
Anae109_0077	ENOG4105DWF	phosphomethylpyrimidine kinase
Anae109_0078	ENOG4105CDU	Replicative dna helicase
Anae109_0080	ENOG4105CJW	magnesium transporter
Anae109_0087	ENOG4105C3R	Methionine synthase
Anae109_0091	ENOG4105D7A	ATP-binding protein
Anae109_0092	ENOG4105CKK	Glycosyl transferase, family 2
Anae109_0094	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Anae109_0095	ENOG4108VPT	UPF0234 protein
Anae109_0096	ENOG4105CN5	Metallo-Beta-Lactamase
Anae109_0098	ENOG4105C4R	Atp-dependent dna helicase
Anae109_0100	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
Anae109_0101	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
Anae109_0102	ENOG4105BZU	Histidine kinase
Anae109_0106	ENOG4105BZU	Histidine kinase
Anae109_0110	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_0111	ENOG4105BZU	Histidine kinase
Anae109_0117	ENOG4105DFF	Rod shape-determining protein mreb
Anae109_0118	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
Anae109_0119	ENOG4105D9P	serine threonine protein kinase
Anae109_0120	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Anae109_0121	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Anae109_0122	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
Anae109_0123	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Anae109_0124	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Anae109_0125	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Anae109_0126	ENOG4105K4W	Could be involved in septation (By similarity)
Anae109_0127	ENOG4107Z7S	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Anae109_0129	ENOG4105CTD	carboxy-peptidase
Anae109_0130	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
Anae109_0131	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
Anae109_0136	ENOG4105BZU	Histidine kinase
Anae109_0139	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
Anae109_0143	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
Anae109_0145	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Anae109_0149	ENOG410812K	response regulator receiver protein
Anae109_0151	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
Anae109_0152	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Anae109_0153	ENOG4108EQA	pts system
Anae109_0156	ENOG4105F3R	pts system mannose fructose sorbose family iid
Anae109_0158	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Anae109_0159	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Anae109_0160	ENOG41089UC	methyltransferase, type 11
Anae109_0161	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
Anae109_0163	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Anae109_0165	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
Anae109_0167	ENOG4105DKQ	ROK family
Anae109_0169	ENOG4105SG9	biopolymer transport protein, ExbD
Anae109_0170	ENOG4105E02	MotA TolQ exbB proton channel
Anae109_0180	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Anae109_0181	ENOG4105CAS	nag kinase
Anae109_0182	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Anae109_0187	ENOG4107RBB	ABC transporter, permease
Anae109_0191	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Anae109_0196	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
Anae109_0197	ENOG4107YU2	histidine triad (hIT) protein
Anae109_0201	ENOG4105KHN	chorismate mutase
Anae109_0202	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Anae109_0203	ENOG4105EVN	Prephenate dehydrogenase
Anae109_0204	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Anae109_0205	ENOG4105E2X	shikimate dehydrogenase
Anae109_0206	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Anae109_0208	ENOG4105D49	3-dehydroquinate synthase
Anae109_0209	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
Anae109_0210	ENOG4105CKK	Glycosyl transferase, family 2
Anae109_0212	ENOG4105C34	Pseudouridine synthase
Anae109_0220	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Anae109_0221	ENOG4107RGD	Major Facilitator superfamily
Anae109_0226	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
Anae109_0227	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
Anae109_0228	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
Anae109_0230	ENOG4105FDR	Membrane
Anae109_0236	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
Anae109_0240	ENOG4105BZ8	glutamate synthase
Anae109_0250	ENOG4105K6V	RNA polymerase
Anae109_0252	ENOG4107QI1	Mate efflux family protein
Anae109_0254	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
Anae109_0257	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Anae109_0258	ENOG4105MJ2	Competence protein
Anae109_0264	ENOG4105EPD	Oligopeptide transporter, Opt family
Anae109_0266	ENOG4108RQS	Two component transcriptional regulator (Winged helix family
Anae109_0267	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Anae109_0268	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
Anae109_0271	ENOG4107QX3	carboxylase
Anae109_0273	ENOG4105VEQ	Cold shock protein
Anae109_0274	ENOG4107QWG	2-Nitropropane dioxygenase
Anae109_0276	ENOG4106HNH	Acyl-transferase
Anae109_0278	ENOG41065SU	Two-component system sensor kinase
Anae109_0279	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Anae109_0280	ENOG4107QSA	Oxaloacetate decarboxylase
Anae109_0282	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Anae109_0287	ENOG4105C34	Pseudouridine synthase
Anae109_0288	ENOG4105M8F	Biopolymer transport protein exbD tolR
Anae109_0292	ENOG4108KPZ	tonB-dependent Receptor
Anae109_0294	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Anae109_0295	ENOG4105CE9	30S ribosomal protein S2
Anae109_0298	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
Anae109_0299	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
Anae109_0302	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Anae109_0303	ENOG4105DJ0	Poly(A) Polymerase
Anae109_0304	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Anae109_0305	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Anae109_0307	ENOG41084UG	Pfam:DUF1458
Anae109_0309	ENOG4105CSR	polyphosphate kinase 2
Anae109_0318	ENOG4107S1W	4-alpha-glucanotransferase
Anae109_0319	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Anae109_0322	ENOG4105CPQ	Dehydrogenase
Anae109_0323	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Anae109_0327	ENOG4108903	Formimidoylglutamase
Anae109_0328	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
Anae109_0329	ENOG4108V5V	Serine Threonine protein kinase
Anae109_0330	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Anae109_0331	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
Anae109_0347	ENOG4108JIC	nucleoside recognition domain protein
Anae109_0349	ENOG4108ZVT	methylmalonyl-coA epimerase
Anae109_0352	ENOG4105CH7	arginosuccinase
Anae109_0353	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
Anae109_0354	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
Anae109_0355	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
Anae109_0356	ENOG4105ERH	Fumarylacetoacetate hydrolase
Anae109_0357	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
Anae109_0361	ENOG4108R5S	membrane
Anae109_0362	ENOG4105FB2	class II Aldolase
Anae109_0363	ENOG4105C2X	Arabinose 5-phosphate isomerase
Anae109_0364	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Anae109_0367	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Anae109_0368	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
Anae109_0370	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
Anae109_0371	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Anae109_0372	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
Anae109_0373	ENOG4105DK0	Indole-3-glycerol phosphate synthase
Anae109_0374	ENOG4108I0Q	anthranilate phosphoribosyltransferase
Anae109_0375	ENOG4105DDQ	anthranilate synthase
Anae109_0376	ENOG4105CRQ	synthase (Component I)
Anae109_0377	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
Anae109_0380	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Anae109_0384	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Anae109_0385	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Anae109_0386	ENOG4105CJN	penicillin-binding protein
Anae109_0388	ENOG4107ZT5	Thiol disulfide interchange protein
Anae109_0390	ENOG410900P	UPF0336 protein
Anae109_0394	ENOG4105E02	MotA TolQ exbB proton channel
Anae109_0395	ENOG4105SG9	biopolymer transport protein, ExbD
Anae109_0396	ENOG4105NWN	ApaG protein
Anae109_0397	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Anae109_0401	ENOG41083V2	Pterin carbinolamine dehydratase
Anae109_0402	ENOG4105M08	Membrane
Anae109_0403	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
Anae109_0404	ENOG4105DUX	Transporter
Anae109_0405	ENOG4105DUX	Transporter
Anae109_0406	ENOG4107QRT	dEAD DEAH box helicase
Anae109_0412	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
Anae109_0413	ENOG4105BZU	Histidine kinase
Anae109_0415	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Anae109_0416	ENOG4105BZU	Histidine kinase
Anae109_0419	ENOG4105C8U	phosphate abc transporter
Anae109_0420	ENOG4105E2Z	phosphate ABC transporter (Permease
Anae109_0421	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Anae109_0422	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
Anae109_0430	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
Anae109_0431	ENOG4106WTF	Glycosyl transferase, family 2
Anae109_0433	ENOG4105C5H	ABC transporter
Anae109_0435	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
Anae109_0438	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Anae109_0442	ENOG4105ETX	regulatoR
Anae109_0444	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Anae109_0447	ENOG4105DJV	ribulose-phosphate 3-epimerase
Anae109_0456	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Anae109_0457	ENOG4108UJU	UPF0301 protein
Anae109_0459	ENOG4105DCG	PHP domain protein
Anae109_0462	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Anae109_0463	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Anae109_0464	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
Anae109_0466	ENOG4108KTQ	Methyltransferase
Anae109_0467	ENOG4105M3Z	response regulator
Anae109_0469	ENOG4105CBS	Chea signal transduction histidine kinase
Anae109_0470	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Anae109_0472	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Anae109_0473	ENOG4105C3M	thioredoxin reductase
Anae109_0474	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
Anae109_0475	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Anae109_0476	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Anae109_0478	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Anae109_0481	ENOG4105EBM	Alpha Beta Hydrolase Fold protein
Anae109_0482	ENOG4105D3R	alkyl hydroperoxide reductase
Anae109_0484	ENOG4105MHT	Transcriptional regulator, ARSR family
Anae109_0486	ENOG4107SC1	transglycosylase
Anae109_0488	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
Anae109_0493	ENOG4108DG9	Smr protein MutS2
Anae109_0495	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Anae109_0497	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Anae109_0501	ENOG4107STQ	Multicopper oxidase
Anae109_0502	ENOG4105C6K	Malic enzyme
Anae109_0506	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_0507	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Anae109_0509	ENOG4105QUH	Domain of unknown function (DUF2088)
Anae109_0512	ENOG41066UM	arsR family transcriptional regulator
Anae109_0517	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
Anae109_0519	ENOG4105C8H	hydrogenase maturation protein Hypf
Anae109_0521	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
Anae109_0522	ENOG4108USZ	hydrogenase
Anae109_0523	ENOG4105DPX	Hydrogenase, large subunit
Anae109_0524	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
Anae109_0525	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Anae109_0526	ENOG4105E3S	small subunit
Anae109_0529	ENOG4105BZU	Histidine kinase
Anae109_0531	ENOG4105KT7	mgtC SapB transporter
Anae109_0539	ENOG4105BZU	Histidine kinase
Anae109_0540	ENOG4105BZU	Histidine kinase
Anae109_0541	ENOG4105BZU	Histidine kinase
Anae109_0545	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Anae109_0546	ENOG4108ZG0	Ompa motb domain protein
Anae109_0550	ENOG4107SET	aldo keto reductase
Anae109_0558	ENOG4105D94	Major Facilitator Superfamily
Anae109_0559	ENOG4108VGI	doxx family
Anae109_0564	ENOG4105E6M	Sulphatase-modifying factor protein
Anae109_0567	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
Anae109_0568	ENOG4105BZS	acriflavin resistance protein
Anae109_0569	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
Anae109_0572	ENOG4105F0N	pyrophosphate phospho-hydrolase
Anae109_0573	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
Anae109_0574	ENOG4105C9X	ppx gppa phosphatase
Anae109_0582	ENOG4105DQV	Component of the cytochrome b6-f complex, which mediates electron transfer between photosystem II (PSII) and photosystem I (PSI), cyclic electron flow around PSI, and state transitions (By similarity)
Anae109_0588	ENOG4108NVR	Methyl-accepting chemotaxis
Anae109_0595	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
Anae109_0596	ENOG4108J5G	6-phosphogluconate dehydrogenase
Anae109_0598	ENOG4108ZM9	phosphoglycerate mutase
Anae109_0600	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
Anae109_0601	ENOG4108JUA	Transcriptional regulator
Anae109_0602	ENOG4105MHT	Transcriptional regulator, ARSR family
Anae109_0607	ENOG4107R3N	Filamentation induced by cAMP protein fic
Anae109_0610	ENOG4105BZK	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair (By similarity)
Anae109_0611	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Anae109_0612	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Anae109_0613	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
Anae109_0615	ENOG4105ETX	regulatoR
Anae109_0616	ENOG4105JAB	phenazine biosynthesis protein, phzf family
Anae109_0619	ENOG4105C1V	Peptidase, M16
Anae109_0620	ENOG4105BZU	Histidine kinase
Anae109_0625	ENOG4108KXV	response regulator
Anae109_0631	ENOG410682Y	Regulates arginine biosynthesis genes (By similarity)
Anae109_0632	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
Anae109_0633	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
Anae109_0636	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
Anae109_0637	ENOG4105C3J	Cysteine desulfurase
Anae109_0638	ENOG4107XTC	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins
Anae109_0639	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
Anae109_0640	ENOG4108SWN	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA (By similarity)
Anae109_0641	ENOG4105C9I	Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB
Anae109_0642	ENOG4108ZIT	Ferredoxin, 2FE-2S
Anae109_0643	ENOG4105WVQ	Fe-S assembly protein IscX
Anae109_0644	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Anae109_0645	ENOG4105BZU	Histidine kinase
Anae109_0646	ENOG4108V3W	Chemotaxis protein, CheW
Anae109_0647	ENOG4105CBS	Chea signal transduction histidine kinase
Anae109_0648	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
Anae109_0650	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Anae109_0653	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Anae109_0654	ENOG4108V3W	Chemotaxis protein, CheW
Anae109_0656	ENOG4108QAF	Methyl-accepting chemotaxis sensory transducer
Anae109_0657	ENOG4105CBS	Chea signal transduction histidine kinase
Anae109_0658	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Anae109_0659	ENOG4105BZU	Histidine kinase
Anae109_0660	ENOG4108UXN	response regulator
Anae109_0661	ENOG4105CDY	transcriptional regulatory protein
Anae109_0665	ENOG4105KG3	cytidine deaminase
Anae109_0666	ENOG4105DTN	riboflavin biosynthesis protein ribF
Anae109_0667	ENOG4107QHF	type ii secretion system protein e
Anae109_0668	ENOG4105CZX	twitching motility protein
Anae109_0670	ENOG4105BZU	Histidine kinase
Anae109_0671	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_0680	ENOG4106855	Competence protein
Anae109_0682	ENOG4105EHH	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue (By similarity)
Anae109_0683	ENOG4105BZU	Histidine kinase
Anae109_0684	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_0690	ENOG4105E4G	Type IV pilus
Anae109_0693	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Anae109_0694	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
Anae109_0695	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Anae109_0699	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Anae109_0700	ENOG4105C59	p-type ATPase
Anae109_0701	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Anae109_0702	ENOG4105C9X	ppx gppa phosphatase
Anae109_0705	ENOG4105M8F	Biopolymer transport protein exbD tolR
Anae109_0706	ENOG4105E02	MotA TolQ exbB proton channel
Anae109_0708	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Anae109_0710	ENOG4105CAK	Cell division ATP-binding protein ftsE
Anae109_0711	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
Anae109_0712	ENOG41063SB	peptidase
Anae109_0713	ENOG4105CN1	protease
Anae109_0714	ENOG4105CND	Glycosyl transferase, family 2
Anae109_0716	ENOG4108SHN	Glycosyl transferase, family 2
Anae109_0717	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Anae109_0718	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Anae109_0719	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
Anae109_0724	ENOG4108WWZ	General secretion pathway protein J
Anae109_0727	ENOG4108VAU	general secretion pathway protein G
Anae109_0728	ENOG4105D7Q	type ii secretion system
Anae109_0729	ENOG4107QHF	type ii secretion system protein e
Anae109_0730	ENOG4105GVR	general secretion pathway protein D
Anae109_0732	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_0733	ENOG41082DI	50s ribosomal protein l31
Anae109_0734	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Anae109_0735	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Anae109_0736	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
Anae109_0738	ENOG4105C03	ribonuclease
Anae109_0739	ENOG4107S2Z	UPF0761 membrane protein
Anae109_0740	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Anae109_0742	ENOG4105D00	flagellar biosynthetic protein flhB
Anae109_0745	ENOG4105CN7	Flagellar biosynthetic protein FliP
Anae109_0748	ENOG4108RBT	type iii secretion
Anae109_0753	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
Anae109_0754	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
Anae109_0755	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
Anae109_0756	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
Anae109_0757	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
Anae109_0759	ENOG41084JP	30S ribosomal protein S21
Anae109_0761	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Anae109_0762	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Anae109_0764	ENOG4105CVJ	phosphoglycerate mutase
Anae109_0766	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Anae109_0768	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
Anae109_0770	ENOG4105C25	Primosomal protein n'
Anae109_0774	ENOG4105D1H	recombination factor protein RarA
Anae109_0775	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
Anae109_0776	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
Anae109_0777	ENOG4108ZF3	Phosphatase
Anae109_0778	ENOG4105DR5	peptidase
Anae109_0780	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Anae109_0785	ENOG4105F4G	Membrane
Anae109_0787	ENOG4107T8T	UPF0173 metal-dependent hydrolase
Anae109_0788	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Anae109_0789	ENOG4105DR5	peptidase
Anae109_0790	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
Anae109_0791	ENOG4105K56	Transcriptional regulator
Anae109_0798	ENOG4105HEE	Binding Domain protein
Anae109_0799	ENOG4107MMM	Anti-sigma-factor antagonist
Anae109_0800	ENOG4105FUA	antagonist
Anae109_0801	ENOG4105QD0	anti-sigma regulatory factor serine threonine protein kinase
Anae109_0803	ENOG4105BZU	Histidine kinase
Anae109_0804	ENOG4105GR3	Histidine kinase
Anae109_0805	ENOG4105FR1	rard protein
Anae109_0806	ENOG41081QV	Universal stress protein
Anae109_0808	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
Anae109_0811	ENOG4108RAC	Rubrerythrin
Anae109_0815	ENOG4107R7Y	intracellular protease Pfpi family
Anae109_0819	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
Anae109_0821	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Anae109_0825	ENOG4107VBM	3-beta hydroxysteroid dehydrogenase isomerase
Anae109_0828	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Anae109_0829	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
Anae109_0830	ENOG4105C7S	Dehydrogenase
Anae109_0832	ENOG4105DQE	DNA ligase
Anae109_0833	ENOG4105CQ7	ATP-dependent helicase
Anae109_0834	ENOG4108W2P	Methyl-accepting chemotaxis
Anae109_0836	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
Anae109_0837	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
Anae109_0839	ENOG4105EMN	RNA polymerase sigma factor
Anae109_0841	ENOG4107SFQ	iron-sulfur binding
Anae109_0848	ENOG4105Z4T	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
Anae109_0852	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_0855	ENOG4105BZ8	glutamate synthase
Anae109_0859	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Anae109_0861	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Anae109_0862	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Anae109_0864	ENOG4105EEM	helicase
Anae109_0865	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
Anae109_0872	ENOG4105SG9	biopolymer transport protein, ExbD
Anae109_0873	ENOG4105E02	MotA TolQ exbB proton channel
Anae109_0878	ENOG4105C5H	ABC transporter
Anae109_0880	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
Anae109_0881	ENOG4105EB3	Histidine kinase
Anae109_0884	ENOG4108JGH	Tetr family transcriptional regulator
Anae109_0885	ENOG4108IXY	short-chain dehydrogenase reductase
Anae109_0887	ENOG4105C26	Dehydrogenase
Anae109_0890	ENOG4105BZU	Histidine kinase
Anae109_0893	ENOG4105CJ1	ABC, transporter
Anae109_0894	ENOG4105CJ1	ABC, transporter
Anae109_0895	ENOG4107QWP	ABC-2 type transporter
Anae109_0896	ENOG4107QWP	ABC-2 type transporter
Anae109_0897	ENOG4105DA5	(ABC) transporter
Anae109_0898	ENOG4105E3A	(ABC) transporter
Anae109_0900	ENOG4105C9U	ATP-dependent DNA helicase RecQ
Anae109_0901	ENOG4108VWS	Yaeq family
Anae109_0906	ENOG4105C9B	Cysteine desulfurase
Anae109_0907	ENOG4108UNV	SUF system FeS assembly protein, NifU family
Anae109_0912	ENOG4105C0H	protease
Anae109_0915	ENOG4105WH1	Two component transcriptional regulator luxr family
Anae109_0920	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Anae109_0924	ENOG4108V0P	LemA family
Anae109_0929	ENOG4108JCI	Transcriptional regulator
Anae109_0930	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Anae109_0938	ENOG4105FDF	Could be involved in DNA repair (By similarity)
Anae109_0939	ENOG4105DQE	DNA ligase
Anae109_0941	ENOG4105D64	Mechanosensitive ion channel
Anae109_0944	ENOG4108SJC	Membrane
Anae109_0946	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
Anae109_0949	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
Anae109_0950	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
Anae109_0951	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
Anae109_0953	ENOG410690C	hydroxylamine oxidase
Anae109_0955	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
Anae109_0956	ENOG4108W6G	cytochrome C
Anae109_0965	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_0966	ENOG4105BZU	Histidine kinase
Anae109_0967	ENOG4108IQK	o-acetylhomoserine
Anae109_0970	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
Anae109_0974	ENOG4107QJE	Chromosome Partitioning Protein
Anae109_0975	ENOG4108NVM	synthesis repressor PhaR
Anae109_0978	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
Anae109_0984	ENOG4105C7Z	Conserved Protein
Anae109_0988	ENOG4107QI1	Mate efflux family protein
Anae109_0989	ENOG4105DFH	Transport of potassium into the cell (By similarity)
Anae109_0990	ENOG4107SFI	Major Facilitator superfamily
Anae109_0991	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Anae109_0992	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Anae109_0993	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Anae109_0997	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Anae109_1001	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Anae109_1007	ENOG4105DQE	DNA ligase
Anae109_1010	ENOG4105CYC	Transferase
Anae109_1013	ENOG4105MPN	Membrane
Anae109_1016	ENOG4105BZU	Histidine kinase
Anae109_1017	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_1023	ENOG410624X	efflux transporter, rnd family, mfp subunit
Anae109_1024	ENOG4105BZS	acriflavin resistance protein
Anae109_1027	ENOG4105BZU	Histidine kinase
Anae109_1028	ENOG4105E0M	Sulfatase
Anae109_1030	ENOG4105D8V	Glucose sorbosone dehydrogenase
Anae109_1033	ENOG4108TQ9	Histidine kinase
Anae109_1040	ENOG4105BZU	Histidine kinase
Anae109_1041	ENOG4105C1A	potassium transporter peripheral membrane
Anae109_1042	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
Anae109_1043	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Anae109_1046	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
Anae109_1054	ENOG4107TVJ	,Oxidoreductase FAD NAD(P)-binding
Anae109_1058	ENOG4105CIR	epoxide hydrolase
Anae109_1065	ENOG4107YCR	Transcriptional regulator, ARSR family
Anae109_1076	ENOG4105D5G	Transposase
Anae109_1084	ENOG4106H3A	restriction
Anae109_1088	ENOG4105CHJ	isochorismatase hydrolase
Anae109_1090	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
Anae109_1091	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
Anae109_1093	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
Anae109_1094	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Anae109_1095	ENOG4105D48	metallophosphoesterase
Anae109_1097	ENOG4108SPH	protein kinase (EC 2.7.11.1)
Anae109_1098	ENOG4105C3J	Cysteine desulfurase
Anae109_1100	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
Anae109_1102	ENOG4105CM2	brancheD-chain amino acid aminotransferase
Anae109_1104	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
Anae109_1105	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_1108	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Anae109_1109	ENOG4105EMU	Dehydrogenase
Anae109_1110	ENOG4105ES5	Histidine kinase
Anae109_1113	ENOG4107QPV	Serine Threonine protein kinase
Anae109_1115	ENOG4107RFW	hydrolase family 57
Anae109_1117	ENOG4105CRK	lysyL-tRNA synthetase
Anae109_1119	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Anae109_1120	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Anae109_1122	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Anae109_1123	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
Anae109_1124	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Anae109_1125	ENOG4105GYT	Protein of unknown function (DUF1009)
Anae109_1126	ENOG410864U	UPF0235 protein
Anae109_1128	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
Anae109_1129	ENOG4105D4P	Coproporphyrinogen iii oxidase
Anae109_1130	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
Anae109_1132	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Anae109_1133	ENOG41084YM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Anae109_1134	ENOG4105ETX	regulatoR
Anae109_1135	ENOG4105CTB	Polyprenyl synthetase
Anae109_1136	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
Anae109_1137	ENOG4105DX0	Hemolysin A
Anae109_1138	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
Anae109_1141	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Anae109_1143	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Anae109_1144	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Anae109_1145	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Anae109_1146	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Anae109_1147	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
Anae109_1148	ENOG4105C83	adenylosuccinate lyase
Anae109_1154	ENOG4105C0H	protease
Anae109_1156	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Anae109_1157	ENOG4105CDV	Ompa motb domain protein
Anae109_1158	ENOG4108ESY	Metal dependent phosphohydrolase
Anae109_1159	ENOG4105ETX	regulatoR
Anae109_1160	ENOG4108ZAF	Molybdopterin
Anae109_1161	ENOG4105DZP	Membrane-associated zinc metalloprotease
Anae109_1162	ENOG4105NBF	ammecr1 domain protein
Anae109_1163	ENOG4105E09	nadh pyrophosphatase
Anae109_1167	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Anae109_1169	ENOG4105DPN	Oligoendopeptidase f
Anae109_1173	ENOG4105CP9	extracellular ligand-binding receptor
Anae109_1174	ENOG4105C32	Amino acid ABC transporter (Permease)
Anae109_1175	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Anae109_1176	ENOG4105C0Z	ABC transporter
Anae109_1177	ENOG4108IV0	ABC, transporter
Anae109_1179	ENOG4105C1G	acyl-Coa dehydrogenase
Anae109_1180	ENOG4105VF7	tolerance protein
Anae109_1183	ENOG4108SPH	protein kinase (EC 2.7.11.1)
Anae109_1184	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Anae109_1185	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
Anae109_1187	ENOG41087GE	Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (By similarity)
Anae109_1195	ENOG4105D3R	alkyl hydroperoxide reductase
Anae109_1196	ENOG4107T4V	d-proline reductase
Anae109_1201	ENOG4105CXV	gliding motility protein
Anae109_1203	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
Anae109_1212	ENOG4105CEY	Amp-dependent synthetase and ligase
Anae109_1213	ENOG4105QUH	Domain of unknown function (DUF2088)
Anae109_1217	ENOG4108J2R	molybdopterin oxidoreductase
Anae109_1218	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
Anae109_1222	ENOG4105C58	cytochrome c oxidase accessory protein ccog
Anae109_1229	ENOG4107QQG	Dehydrogenase
Anae109_1230	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Anae109_1241	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Anae109_1244	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Anae109_1247	ENOG4105CAQ	asparagine synthetase
Anae109_1248	ENOG4107RMH	nh(3)-dependent nad( ) synthetase
Anae109_1249	ENOG4105CEY	Amp-dependent synthetase and ligase
Anae109_1262	ENOG4107R7Y	intracellular protease Pfpi family
Anae109_1263	ENOG4105CX6	glutaminyL-tRNA synthetase
Anae109_1264	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Anae109_1268	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
Anae109_1270	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
Anae109_1272	ENOG4105CFG	Acts as a chaperone (By similarity)
Anae109_1273	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Anae109_1275	ENOG4105CYW	agmatinase
Anae109_1276	ENOG4105E0R	Deoxyhypusine synthase
Anae109_1277	ENOG4105KPV	Transcriptional regulator
Anae109_1278	ENOG4105DB7	PHP domain protein
Anae109_1279	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Anae109_1280	ENOG4105C8S	subunit m
Anae109_1281	ENOG4105D65	subunit l
Anae109_1282	ENOG41080FQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Anae109_1284	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Anae109_1285	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
Anae109_1286	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Anae109_1287	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Anae109_1288	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Anae109_1289	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Anae109_1290	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Anae109_1291	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Anae109_1292	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Anae109_1293	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Anae109_1295	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
Anae109_1296	ENOG41081XG	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Anae109_1299	ENOG4105EYM	Major Facilitator superfamily
Anae109_1302	ENOG4105DCG	PHP domain protein
Anae109_1304	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
Anae109_1305	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Anae109_1309	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Anae109_1311	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Anae109_1312	ENOG4105KME	endoribonuclease L-psp
Anae109_1317	ENOG4105DQR	SNARE associated Golgi
Anae109_1318	ENOG4105JFG	SpoIID LytB domain protein
Anae109_1319	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
Anae109_1323	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Anae109_1324	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Anae109_1327	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
Anae109_1335	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Anae109_1336	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
Anae109_1339	ENOG4107TE5	Lipid kinase
Anae109_1341	ENOG4105C0D	helicase
Anae109_1346	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
Anae109_1348	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Anae109_1357	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
Anae109_1365	ENOG4105DFA	alanine racemase domain protein
Anae109_1366	ENOG4108Z03	MAF-like protein
Anae109_1370	ENOG4105CJN	penicillin-binding protein
Anae109_1371	ENOG4105CNI	cell division protein FtsW
Anae109_1372	ENOG4105K63	Thioredoxin
Anae109_1374	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Anae109_1375	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
Anae109_1378	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
Anae109_1385	ENOG4105WH1	Two component transcriptional regulator luxr family
Anae109_1388	ENOG41080HI	glycine oxidase
Anae109_1389	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
Anae109_1396	ENOG4106PBJ	Serine threonine-protein kinase Pkn6
Anae109_1398	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Anae109_1399	ENOG4105DC1	bifunctional purine biosynthesis protein purh
Anae109_1400	ENOG4105C12	Phosphoribosylglycinamide synthetase
Anae109_1405	ENOG4105MFV	ABC-2 type transporter
Anae109_1408	ENOG4105K64	Glycosyl transferase, family 2
Anae109_1409	ENOG4105E2K	Glycosyl transferase (Group 1
Anae109_1410	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
Anae109_1412	ENOG4105D3Q	Sugar transferase
Anae109_1413	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Anae109_1415	ENOG4105D52	delta-aminolevulinic acid dehydratase
Anae109_1418	ENOG4105CPF	Cell wall formation (By similarity)
Anae109_1424	ENOG4107T8Q	Glycosyl transferase (Group 1
Anae109_1425	ENOG4105E2K	Glycosyl transferase (Group 1
Anae109_1426	ENOG4108PQP	glycosyl transferase group 1
Anae109_1432	ENOG4105CPF	Cell wall formation (By similarity)
Anae109_1436	ENOG4107QR9	Iron-sulfur cluster binding protein
Anae109_1437	ENOG4107R5T	Cysteine-rich domain
Anae109_1438	ENOG4105DAA	L-lactate
Anae109_1440	ENOG4108NEV	two component transcriptional regulator, LytTR family
Anae109_1441	ENOG4108HRK	Histidine kinase
Anae109_1443	ENOG41084I1	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
Anae109_1445	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Anae109_1447	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
Anae109_1448	ENOG4105EJ9	Membrane
Anae109_1450	ENOG41080XQ	Signal transduction protein with cbs domains
Anae109_1451	ENOG4108IV0	ABC, transporter
Anae109_1452	ENOG4105C0Z	ABC transporter
Anae109_1453	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Anae109_1454	ENOG4105C32	Amino acid ABC transporter (Permease)
Anae109_1457	ENOG4105C98	muts2 protein
Anae109_1460	ENOG4105E2K	Glycosyl transferase (Group 1
Anae109_1462	ENOG4105EHZ	conserved protein UCP016719
Anae109_1466	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Anae109_1467	ENOG4105D78	K07001 NTE family protein
Anae109_1472	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Anae109_1474	ENOG4105BZU	Histidine kinase
Anae109_1477	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Anae109_1478	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
Anae109_1479	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
Anae109_1480	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
Anae109_1483	ENOG4105CJR	Integral membrane protein (MviN
Anae109_1487	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
Anae109_1489	ENOG4105EMN	RNA polymerase sigma factor
Anae109_1491	ENOG4105DR4	Methyltransferase
Anae109_1492	ENOG4105BZU	Histidine kinase
Anae109_1495	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
Anae109_1496	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Anae109_1498	ENOG4105BZU	Histidine kinase
Anae109_1500	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
Anae109_1502	ENOG4107QX8	SPFH domain, Band 7 family protein
Anae109_1503	ENOG4105D44	asparaginase
Anae109_1504	ENOG4105CHU	acetyl-coa acetyltransferase
Anae109_1505	ENOG4105D6N	CoA-transferase, subunit a
Anae109_1509	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Anae109_1511	ENOG4105D0M	Protease HtpX homolog
Anae109_1518	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Anae109_1520	ENOG4108Z0R	Transferase
Anae109_1521	ENOG4105IJJ	transcriptional regulator, crp fnr family
Anae109_1522	ENOG4108VD1	dedA family
Anae109_1523	ENOG4105CFG	Acts as a chaperone (By similarity)
Anae109_1524	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Anae109_1525	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Anae109_1532	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
Anae109_1534	ENOG4108P3C	
Anae109_1536	ENOG4105FDK	ABC transporter
Anae109_1538	ENOG4105BZU	Histidine kinase
Anae109_1543	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
Anae109_1544	ENOG4105KAK	Plasmid pRiA4b ORF-3 family protein
Anae109_1545	ENOG4105WG9	Conserved Protein
Anae109_1558	ENOG4105E18	UPF0276 protein
Anae109_1564	ENOG4107S5I	aldo keto reductase
Anae109_1568	ENOG4105R8A	Heat shock protein
Anae109_1572	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
Anae109_1573	ENOG4105E0C	molybdate abc transporter
Anae109_1574	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
Anae109_1588	ENOG4105E9K	Isocitrate dehydrogenase
Anae109_1589	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Anae109_1591	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Anae109_1596	ENOG4105D22	carbon starvation protein
Anae109_1597	ENOG4105BZU	Histidine kinase
Anae109_1603	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_1609	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Anae109_1612	ENOG4105CDY	transcriptional regulatory protein
Anae109_1615	ENOG4105E63	Pfam:DUF178
Anae109_1616	ENOG4105ENX	hydrolase
Anae109_1617	ENOG4105CJ1	ABC, transporter
Anae109_1625	ENOG4105CEP	NADH dehydrogenase
Anae109_1629	ENOG4105CRQ	synthase (Component I)
Anae109_1631	ENOG4105C5H	ABC transporter
Anae109_1636	ENOG4105EWI	Short-chain dehydrogenase reductase Sdr
Anae109_1638	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
Anae109_1639	ENOG4108IJ6	ABC transporter
Anae109_1640	ENOG4105ECW	sulfate abc transporter
Anae109_1641	ENOG4108I5D	sulfate abc transporter
Anae109_1642	ENOG4107UCJ	Catalyzes the synthesis of activated sulfate (By similarity)
Anae109_1643	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
Anae109_1649	ENOG4105CEY	Amp-dependent synthetase and ligase
Anae109_1652	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Anae109_1655	ENOG4105C4M	(Ubiquinol oxidase) subunit I
Anae109_1656	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
Anae109_1662	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Anae109_1664	ENOG4105EG2	ABC transporter, permease
Anae109_1666	ENOG4108YYH	Nadph-dependent fmn reductase
Anae109_1671	ENOG4105C08	Histidine kinase
Anae109_1672	ENOG410841Q	phosphoesterase PA-phosphatase related protein
Anae109_1674	ENOG4105DTD	Dehydrogenase
Anae109_1676	ENOG4105C32	Amino acid ABC transporter (Permease)
Anae109_1678	ENOG4108IV0	ABC, transporter
Anae109_1679	ENOG4105C0Z	ABC transporter
Anae109_1681	ENOG4105CPC	Aldo Keto reductase
Anae109_1684	ENOG4105NXH	GreA GreB family elongation factor
Anae109_1694	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Anae109_1697	ENOG4107T3P	ABC, transporter
Anae109_1699	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
Anae109_1701	ENOG4105WD1	Membrane
Anae109_1703	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
Anae109_1704	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
Anae109_1707	ENOG4108V0P	LemA family
Anae109_1708	ENOG4105D0M	Protease HtpX homolog
Anae109_1710	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
Anae109_1713	ENOG4105CRE	cytochrome C
Anae109_1719	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
Anae109_1720	ENOG4105DEU	major facilitator superfamily
Anae109_1722	ENOG4105BZU	Histidine kinase
Anae109_1724	ENOG4107QRT	dEAD DEAH box helicase
Anae109_1725	ENOG4108S0J	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'- phosphates (By similarity)
Anae109_1732	ENOG4105CTQ	phosphohexokinase
Anae109_1733	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
Anae109_1741	ENOG4108Z66	YbaK ebsC protein
Anae109_1743	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Anae109_1744	ENOG4105CIN	aminoacyl-histidine dipeptidase
Anae109_1753	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Anae109_1754	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
Anae109_1755	ENOG4105ERG	peptidase m48, ste24p
Anae109_1757	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Anae109_1759	ENOG4105CK7	Sodium proline symporter
Anae109_1760	ENOG4105C0F	tryptophanase EC 4.1.99.1
Anae109_1765	ENOG4105DWF	phosphomethylpyrimidine kinase
Anae109_1767	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Anae109_1772	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Anae109_1773	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Anae109_1775	ENOG4105VS7	Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation (By similarity)
Anae109_1778	ENOG4107QZ7	Cellulose synthase catalytic subunit
Anae109_1782	ENOG4107VEG	TrkA-N domain protein
Anae109_1790	ENOG4105VW4	glutaredoxin 3
Anae109_1791	ENOG4105D0M	Protease HtpX homolog
Anae109_1792	ENOG41063Z6	transcriptional regulator, lysR family
Anae109_1793	ENOG4105DU1	integral membrane protein, terc
Anae109_1795	ENOG4105CIY	formyltetrahydrofolate deformylase
Anae109_1798	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_1800	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Anae109_1801	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
Anae109_1807	ENOG4105D0M	Protease HtpX homolog
Anae109_1810	ENOG4105WH1	Two component transcriptional regulator luxr family
Anae109_1815	ENOG41089UC	methyltransferase, type 11
Anae109_1821	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
Anae109_1822	ENOG4105K64	Glycosyl transferase, family 2
Anae109_1825	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
Anae109_1830	ENOG4108XZB	Cytochrome c
Anae109_1845	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
Anae109_1846	ENOG4105BZU	Histidine kinase
Anae109_1847	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_1848	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Anae109_1851	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Anae109_1853	ENOG4105CI3	gtp-binding protein typa
Anae109_1854	ENOG4105BZU	Histidine kinase
Anae109_1855	ENOG4105BZU	Histidine kinase
Anae109_1864	ENOG4105D7N	magnesium and cobalt transport protein CorA
Anae109_1866	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Anae109_1870	ENOG4105BZU	Histidine kinase
Anae109_1874	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
Anae109_1875	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Anae109_1876	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
Anae109_1880	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
Anae109_1881	ENOG4108A8W	50s ribosomal protein L35
Anae109_1882	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Anae109_1883	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Anae109_1884	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Anae109_1886	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
Anae109_1887	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
Anae109_1888	ENOG4105EUJ	GTP cyclohydrolase i
Anae109_1890	ENOG4105CQB	FAD linked oxidase domain protein
Anae109_1891	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Anae109_1892	ENOG4105DQU	oxidoreductase, subunit beta
Anae109_1894	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Anae109_1895	ENOG4105DQU	oxidoreductase, subunit beta
Anae109_1903	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
Anae109_1907	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Anae109_1908	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Anae109_1909	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Anae109_1910	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Anae109_1912	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Anae109_1913	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Anae109_1914	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Anae109_1915	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Anae109_1916	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Anae109_1917	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Anae109_1918	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Anae109_1919	ENOG4108FGF	50s ribosomal protein l29
Anae109_1920	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Anae109_1921	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Anae109_1922	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Anae109_1923	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Anae109_1924	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Anae109_1925	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Anae109_1926	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Anae109_1927	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
Anae109_1928	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Anae109_1930	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Anae109_1931	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Anae109_1932	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Anae109_1935	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Anae109_1936	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
Anae109_1937	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Anae109_1938	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Anae109_1939	ENOG4108ZT0	50S ribosomal protein l17
Anae109_1941	ENOG4105K5M	30s ribosomal protein S16
Anae109_1942	ENOG4105VB6	UPF0109 protein
Anae109_1943	ENOG41082N4	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Anae109_1944	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Anae109_1945	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Anae109_1947	ENOG41082RQ	UPF0102 protein
Anae109_1952	ENOG4105BZU	Histidine kinase
Anae109_1958	ENOG4105C34	Pseudouridine synthase
Anae109_1964	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
Anae109_1966	ENOG41084UG	Pfam:DUF1458
Anae109_1974	ENOG4105C34	Pseudouridine synthase
Anae109_1982	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
Anae109_1990	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Anae109_1991	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Anae109_1992	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
Anae109_1994	ENOG4105CPP	Dehydrogenase, E1 component
Anae109_1997	ENOG4105CUZ	uba thif-type nad fad binding protein
Anae109_1999	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
Anae109_2001	ENOG4105CZK	Aspartate kinase
Anae109_2005	ENOG4105BZU	Histidine kinase
Anae109_2006	ENOG4105CHM	Aminotransferase
Anae109_2007	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Anae109_2008	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Anae109_2009	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Anae109_2010	ENOG4108MG3	formate dehydrogenase
Anae109_2011	ENOG4105F46	Necessary for formate dehydrogenase activity (By similarity)
Anae109_2022	ENOG4105CFG	Acts as a chaperone (By similarity)
Anae109_2026	ENOG4108YZG	isomerase
Anae109_2029	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Anae109_2030	ENOG4105BZU	Histidine kinase
Anae109_2037	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
Anae109_2038	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
Anae109_2041	ENOG4105CY0	Metallo-Beta-Lactamase
Anae109_2045	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Anae109_2046	ENOG4105C0H	protease
Anae109_2052	ENOG4105D82	Glutamate dehydrogenase
Anae109_2053	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
Anae109_2061	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
Anae109_2062	ENOG4105PGM	cation diffusion facilitator family transporter
Anae109_2064	ENOG4106H78	methyltransferase
Anae109_2065	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Anae109_2072	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
Anae109_2075	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Anae109_2077	ENOG4105CHM	Aminotransferase
Anae109_2080	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Anae109_2081	ENOG4105CEV	competence damage-inducible protein
Anae109_2086	ENOG4107QP8	phosphohexose isomerase
Anae109_2088	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
Anae109_2092	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_2096	ENOG4105CPC	Aldo Keto reductase
Anae109_2098	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Anae109_2104	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Anae109_2106	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
Anae109_2107	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Anae109_2110	ENOG4108556	Isoprenoid biosynthesis protein with amidotransferase-like domain
Anae109_2111	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Anae109_2112	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
Anae109_2113	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
Anae109_2116	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
Anae109_2117	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Anae109_2118	ENOG4108Z4T	Peptidase M50
Anae109_2119	ENOG4105C31	Tryptophanyl-tRNA synthetase
Anae109_2120	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
Anae109_2121	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Anae109_2122	ENOG4105FE9	pseudouridine synthase
Anae109_2128	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
Anae109_2129	ENOG4105D7N	magnesium and cobalt transport protein CorA
Anae109_2130	ENOG4105D1F	ATP-binding protein
Anae109_2134	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Anae109_2135	ENOG4105E39	Enoyl-CoA hydratase
Anae109_2136	ENOG4105C1G	acyl-Coa dehydrogenase
Anae109_2137	ENOG4105C1G	acyl-Coa dehydrogenase
Anae109_2138	ENOG4108303	d-xylulose 5-phosphate d-fructose 6-phosphate phosphoketolase
Anae109_2142	ENOG4105ES5	Histidine kinase
Anae109_2144	ENOG4105EYH	Exonuclease
Anae109_2145	ENOG4107RFY	SbcCD D subunit
Anae109_2147	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
Anae109_2148	ENOG4105D3R	alkyl hydroperoxide reductase
Anae109_2155	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Anae109_2156	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Anae109_2159	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Anae109_2162	ENOG4108UW5	maltose o-acetyltransferase
Anae109_2163	ENOG4105C1G	acyl-Coa dehydrogenase
Anae109_2164	ENOG4107QX3	carboxylase
Anae109_2165	ENOG4105E39	Enoyl-CoA hydratase
Anae109_2166	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
Anae109_2167	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
Anae109_2168	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Anae109_2171	ENOG4105CBT	Fructose-1,6-bisphosphatase
Anae109_2173	ENOG4105D6E	homoserine dehydrogenase
Anae109_2180	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Anae109_2182	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Anae109_2183	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
Anae109_2185	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Anae109_2186	ENOG4108HMX	isocitrate dehydrogenase (NADP)
Anae109_2187	ENOG410901P	UPF0249 protein
Anae109_2188	ENOG4105BZU	Histidine kinase
Anae109_2191	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
Anae109_2193	ENOG4105CXT	aspartate transcarbamylase
Anae109_2194	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
Anae109_2196	ENOG4105C3F	Signal peptidase i
Anae109_2197	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Anae109_2198	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Anae109_2204	ENOG41080RH	Thioredoxin
Anae109_2205	ENOG4108UYB	regulatoR
Anae109_2206	ENOG4105BZU	Histidine kinase
Anae109_2210	ENOG4107SC1	transglycosylase
Anae109_2211	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
Anae109_2215	ENOG4105ETX	regulatoR
Anae109_2218	ENOG4105MRR	Transcriptional regulator (By similarity)
Anae109_2219	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Anae109_2220	ENOG4107QR0	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Anae109_2221	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Anae109_2222	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Anae109_2223	ENOG4108VZM	50s ribosomal protein L10
Anae109_2224	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Anae109_2225	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Anae109_2226	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
Anae109_2228	ENOG4108BB4	50S ribosomal protein L33
Anae109_2229	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Anae109_2230	ENOG4105C2N	RNA methyltransferase TrmH family group 3
Anae109_2232	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
Anae109_2233	ENOG4105CFG	Acts as a chaperone (By similarity)
Anae109_2235	ENOG4105BZU	Histidine kinase
Anae109_2238	ENOG4108Z43	UPF0250 protein
Anae109_2239	ENOG4108IAB	Phoh family
Anae109_2240	ENOG4105BZU	Histidine kinase
Anae109_2242	ENOG4108UQY	Iron-storage protein
Anae109_2247	ENOG41079HR	Phosphate-Selective Porin O and P
Anae109_2250	ENOG4105CE1	Ferrous iron transport protein b
Anae109_2251	ENOG41090R7	Ferric uptake
Anae109_2257	ENOG4105BZU	Histidine kinase
Anae109_2258	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_2259	ENOG4105BZU	Histidine kinase
Anae109_2263	ENOG4105C0H	protease
Anae109_2264	ENOG4105CFG	Acts as a chaperone (By similarity)
Anae109_2266	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Anae109_2269	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Anae109_2272	ENOG4107RIQ	Sulfate adenylate transferase
Anae109_2273	ENOG41081QJ	UBA THIF-type NAD FAD binding
Anae109_2275	ENOG4105D06	uba thif-type nad fad binding protein
Anae109_2278	ENOG4108Z4U	Ferredoxin
Anae109_2280	ENOG4105CP7	Triose-phosphate isomerase
Anae109_2281	ENOG4105BZA	Phosphoglycerate kinase
Anae109_2284	ENOG4105DZ0	fad dependent oxidoreductase
Anae109_2288	ENOG4105C75	arginyL-tRNA synthetase
Anae109_2293	ENOG4108V3W	Chemotaxis protein, CheW
Anae109_2294	ENOG4105BZU	Histidine kinase
Anae109_2296	ENOG4108W2P	Methyl-accepting chemotaxis
Anae109_2297	ENOG4105CBS	Chea signal transduction histidine kinase
Anae109_2298	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Anae109_2301	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Anae109_2302	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
Anae109_2303	ENOG4108JJB	ABC transporter
Anae109_2305	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
Anae109_2309	ENOG4105CAT	Cytidine monophosphate kinase
Anae109_2310	ENOG4105CIH	Imidazole acetol-phosphate transaminase
Anae109_2311	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
Anae109_2312	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Anae109_2315	ENOG4105CGP	Urocanate hydratase
Anae109_2326	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
Anae109_2329	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
Anae109_2330	ENOG4105K8N	protein family UPF0079, ATPase
Anae109_2331	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Anae109_2332	ENOG41082KK	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
Anae109_2333	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
Anae109_2334	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
Anae109_2336	ENOG4105C8B	TIGR00159 family
Anae109_2338	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Anae109_2339	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Anae109_2345	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
Anae109_2346	ENOG4108UYI	beta-alanyl-CoA ammonia lyase
Anae109_2347	ENOG4107CHF	5,6-aminomutase beta subunit
Anae109_2349	ENOG4105EQ5	D-Lysine 5,6-aminomutase alpha subunit
Anae109_2350	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Anae109_2351	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
Anae109_2352	ENOG4105BZU	Histidine kinase
Anae109_2353	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Anae109_2356	ENOG4105BZU	Histidine kinase
Anae109_2358	ENOG41089UC	methyltransferase, type 11
Anae109_2360	ENOG4105K63	Thioredoxin
Anae109_2365	ENOG4105BZU	Histidine kinase
Anae109_2366	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Anae109_2367	ENOG4105CBS	Chea signal transduction histidine kinase
Anae109_2368	ENOG4108QAF	Methyl-accepting chemotaxis sensory transducer
Anae109_2370	ENOG4105BZU	Histidine kinase
Anae109_2373	ENOG4105BZP	glycoside hydrolase 15-related
Anae109_2378	ENOG4108TQ9	Histidine kinase
Anae109_2379	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_2387	ENOG4105BZU	Histidine kinase
Anae109_2389	ENOG4108K4C	ec 3.1.3.12
Anae109_2391	ENOG4105ETX	regulatoR
Anae109_2393	ENOG4108JZA	Homocitrate synthase
Anae109_2397	ENOG4105K6H	D-cysteine desulfhydrase
Anae109_2399	ENOG4105C8Q	Methyl-accepting chemotaxis
Anae109_2401	ENOG4106IUH	DTW domain containing protein
Anae109_2402	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Anae109_2403	ENOG4105DNZ	Alpha Beta Hydrolase
Anae109_2407	ENOG4107SFQ	iron-sulfur binding
Anae109_2409	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Anae109_2417	ENOG4105CD8	aminopeptidase N
Anae109_2422	ENOG41067HS	methyltransferase
Anae109_2423	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
Anae109_2424	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
Anae109_2429	ENOG4108JUA	Transcriptional regulator
Anae109_2430	ENOG4107QT6	homoserine O-acetyltransferase
Anae109_2432	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
Anae109_2433	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
Anae109_2436	ENOG41068KF	Universal stress protein
Anae109_2437	ENOG41080XP	Cbs domain
Anae109_2438	ENOG4108TQ9	Histidine kinase
Anae109_2439	ENOG4106322	response regulator
Anae109_2440	ENOG4105BZU	Histidine kinase
Anae109_2442	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_2443	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Anae109_2445	ENOG4108RWI	nicotinamidase
Anae109_2448	ENOG4105F8V	Hydrolase, tatD family
Anae109_2449	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Anae109_2451	ENOG4107QRG	dna polymerase iii
Anae109_2452	ENOG4105BZU	Histidine kinase
Anae109_2454	ENOG4108V9Q	carbonic anhydrase
Anae109_2455	ENOG4105C2M	dna polymerase I
Anae109_2460	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
Anae109_2461	ENOG4105D7K	pfkb domain protein
Anae109_2462	ENOG410826D	Involved in DNA repair and RecF pathway recombination (By similarity)
Anae109_2467	ENOG4107VRB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
Anae109_2468	ENOG4106S48	Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and or cell division
Anae109_2471	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
Anae109_2474	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Anae109_2476	ENOG4105E55	glycerol-3-phosphate acyltransferase
Anae109_2478	ENOG4107TK4	histidinol-phosphate phosphatase
Anae109_2480	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Anae109_2481	ENOG4107QHF	type ii secretion system protein e
Anae109_2485	ENOG4105F0N	pyrophosphate phospho-hydrolase
Anae109_2486	ENOG4105D7W	serine acetyltransferase
Anae109_2488	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
Anae109_2490	ENOG4105NQN	cytochrome C
Anae109_2491	ENOG4105BZU	Histidine kinase
Anae109_2493	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Anae109_2494	ENOG4105VEQ	Cold shock protein
Anae109_2496	ENOG4105C8N	cysteinyl-tRNA synthetase
Anae109_2497	ENOG4108EM8	Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) (By similarity)
Anae109_2498	ENOG4108VJ1	Transcriptional regulator (CarD family
Anae109_2504	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Anae109_2505	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
Anae109_2507	ENOG4107Z3H	Transcriptional regulator, TetR family
Anae109_2508	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
Anae109_2511	ENOG4108IDZ	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
Anae109_2512	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
Anae109_2513	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
Anae109_2515	ENOG4105VB9	50S ribosomal protein l28
Anae109_2520	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Anae109_2522	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
Anae109_2524	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Anae109_2525	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
Anae109_2529	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
Anae109_2531	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Anae109_2532	ENOG4105VEQ	Cold shock protein
Anae109_2535	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
Anae109_2536	ENOG4105HHA	aminodeoxychorismate lyase
Anae109_2537	ENOG4105CYN	Serine protein kinase
Anae109_2538	ENOG4106AKX	UPF0229 protein
Anae109_2539	ENOG4105ED1	spovr family
Anae109_2540	ENOG4105E4C	Lytic transglycosylase catalytic
Anae109_2544	ENOG4105C1J	atp-dependent rna helicase
Anae109_2545	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Anae109_2549	ENOG4108YZY	peptidylprolyl cis-trans isomerase
Anae109_2553	ENOG4105NZG	Ferredoxin
Anae109_2554	ENOG41063JG	Transcriptional regulator
Anae109_2556	ENOG4105CF7	AraC family transcriptional regulator
Anae109_2557	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Anae109_2558	ENOG4107R95	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Anae109_2560	ENOG4105BZU	Histidine kinase
Anae109_2562	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Anae109_2563	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
Anae109_2564	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
Anae109_2569	ENOG4105EBX	v-type atpase
Anae109_2570	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
Anae109_2573	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Anae109_2574	ENOG4105DSJ	YicC domain protein
Anae109_2575	ENOG4105W49	UPF0434 protein
Anae109_2577	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
Anae109_2578	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
Anae109_2580	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
Anae109_2581	ENOG4105DKP	glycosyl transferase, family 9
Anae109_2582	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
Anae109_2584	ENOG4105BZ1	(ABC) transporter
Anae109_2585	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Anae109_2586	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Anae109_2587	ENOG41081FY	multiple antibiotic resistance (MarC)-related
Anae109_2588	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
Anae109_2589	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
Anae109_2601	ENOG4108URH	decarboxylase
Anae109_2607	ENOG4108PQP	glycosyl transferase group 1
Anae109_2611	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Anae109_2613	ENOG4105CHW	UPF0052 protein
Anae109_2615	ENOG4107YJ4	chain length determinant protein
Anae109_2620	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_2622	ENOG4105D3Q	Sugar transferase
Anae109_2628	ENOG4105CPK	Glycosyl transferase (Group 1
Anae109_2630	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Anae109_2632	ENOG4105D75	Capsular exopolysaccharide family
Anae109_2633	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
Anae109_2636	ENOG4105JFG	SpoIID LytB domain protein
Anae109_2639	ENOG4105F0I	Aminotransferase
Anae109_2646	ENOG4105CAY	ferredoxin--nadp reductase
Anae109_2649	ENOG4105VTR	Integrase
Anae109_2653	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Anae109_2661	ENOG4108M3P	Membrane
Anae109_2667	ENOG4105SYT	Methylenetetrahydrofolate reductase
Anae109_2668	ENOG4108RRZ	Transcription elongation factor GreB
Anae109_2672	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
Anae109_2675	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Anae109_2680	ENOG4105CDH	Citrulline--aspartate ligase
Anae109_2683	ENOG4105CFG	Acts as a chaperone (By similarity)
Anae109_2684	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Anae109_2685	ENOG4105DBV	ornithine carbamoyltransferase
Anae109_2686	ENOG4105C8Y	Acetylornithine aminotransferase
Anae109_2687	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
Anae109_2688	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
Anae109_2689	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Anae109_2691	ENOG4107QXI	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs (By similarity)
Anae109_2693	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Anae109_2694	ENOG4105C79	DNA protecting protein DprA
Anae109_2695	ENOG4108WZM	domain protein
Anae109_2697	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
Anae109_2699	ENOG4106EEU	Response regulator receiver domain
Anae109_2701	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
Anae109_2702	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Anae109_2705	ENOG4105CZX	twitching motility protein
Anae109_2708	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
Anae109_2709	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
Anae109_2712	ENOG4105CTJ	Metal Dependent Phosphohydrolase
Anae109_2714	ENOG4108UJG	
Anae109_2716	ENOG4105DXN	mazG family
Anae109_2719	ENOG4105C8T	Leucyl-tRNA synthetase
Anae109_2720	ENOG4105C5S	asparaginyl-tRNA synthetase
Anae109_2725	ENOG4105FF5	Membrane
Anae109_2727	ENOG4105M7K	Involved in the transcription termination process (By similarity)
Anae109_2728	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
Anae109_2729	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
Anae109_2731	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
Anae109_2732	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Anae109_2733	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Anae109_2734	ENOG4108YZG	isomerase
Anae109_2735	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
Anae109_2736	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Anae109_2737	ENOG4105CHR	reductase
Anae109_2738	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
Anae109_2739	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
Anae109_2740	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
Anae109_2741	ENOG41085D1	50S ribosomal protein L32
Anae109_2747	ENOG4105CRE	cytochrome C
Anae109_2748	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
Anae109_2750	ENOG4107ZXI	Rhomboid family
Anae109_2753	ENOG4105MIR	Phenylalanine 4-monooxygenase
Anae109_2759	ENOG4108VKQ	nitriC oxide reductase
Anae109_2764	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
Anae109_2766	ENOG4105CA0	peroxidase
Anae109_2772	ENOG4105D0M	Protease HtpX homolog
Anae109_2774	ENOG4105CB2	alcohol dehydrogenase
Anae109_2777	ENOG4105E0X	reductase
Anae109_2778	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Anae109_2780	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
Anae109_2783	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
Anae109_2790	ENOG4105CK2	sodium dicarboxylate symporter
Anae109_2792	ENOG41068KF	Universal stress protein
Anae109_2793	ENOG4105DAN	ATP-dependent protease
Anae109_2797	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Anae109_2809	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Anae109_2812	ENOG4105CVJ	phosphoglycerate mutase
Anae109_2813	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Anae109_2815	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
Anae109_2818	ENOG4105C2M	dna polymerase I
Anae109_2819	ENOG4105D3Z	quinone oxidoreductase, yhdh yhfp family
Anae109_2823	ENOG4105C08	Histidine kinase
Anae109_2831	ENOG4105GRZ	Ycii-related protein
Anae109_2832	ENOG4105CHP	RNA polymerase
Anae109_2839	ENOG4108UVJ	appr-1-p processing domain protein
Anae109_2841	ENOG41077A9	carbonic anhydrase
Anae109_2842	ENOG4105ER2	Ompa motb domain protein
Anae109_2846	ENOG4105IIU	Aminopeptidase
Anae109_2847	ENOG4108MR6	WD40-like Beta Propeller Repeat
Anae109_2848	ENOG4105CMU	LysR family (Transcriptional regulator
Anae109_2861	ENOG4105BZ9	Cytochrome C oxidase, subunit I
Anae109_2866	ENOG4107QN1	sodium solute
Anae109_2874	ENOG4105C8Q	Methyl-accepting chemotaxis
Anae109_2875	ENOG4105C1G	acyl-Coa dehydrogenase
Anae109_2876	ENOG4105CHU	acetyl-coa acetyltransferase
Anae109_2878	ENOG4108JU7	Transcriptional regulator
Anae109_2885	ENOG4108V1U	phospholipid-binding protein
Anae109_2886	ENOG4105CPC	Aldo Keto reductase
Anae109_2888	ENOG4108UYE	Lactoylglutathione lyase
Anae109_2891	ENOG4105VC4	domain protein
Anae109_2892	ENOG4105D78	K07001 NTE family protein
Anae109_2895	ENOG4108MP6	LysR family Transcriptional regulator
Anae109_2909	ENOG4107R7I	amino acid
Anae109_2910	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Anae109_2915	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
Anae109_2918	ENOG4108V5V	Serine Threonine protein kinase
Anae109_2919	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
Anae109_2920	ENOG4105EU8	FAD linked oxidase domain protein
Anae109_2921	ENOG4105CQB	FAD linked oxidase domain protein
Anae109_2922	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Anae109_2924	ENOG4105CH5	extracellular solute-binding protein, family 7
Anae109_2928	ENOG410830R	acetyltransferase
Anae109_2929	ENOG4105I8F	Histidine kinase
Anae109_2930	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Anae109_2931	ENOG4105CPQ	Dehydrogenase
Anae109_2941	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
Anae109_2946	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Anae109_2947	ENOG4105EPD	Oligopeptide transporter, Opt family
Anae109_2950	ENOG41080XP	Cbs domain
Anae109_2951	ENOG4105EN6	Membrane
Anae109_2957	ENOG4105C5R	Aminotransferase
Anae109_2961	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Anae109_2963	ENOG4107QP3	malate synthase g
Anae109_2966	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
Anae109_2968	ENOG4105CG3	alpha amylase, catalytic region
Anae109_2971	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
Anae109_2972	ENOG4105W8H	transhydrogenase (subunit alpha
Anae109_2973	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
Anae109_2974	ENOG4105DQ4	alcohol dehydrogenase
Anae109_2976	ENOG4105BZU	Histidine kinase
Anae109_2981	ENOG410624X	efflux transporter, rnd family, mfp subunit
Anae109_2984	ENOG4105CEY	Amp-dependent synthetase and ligase
Anae109_2985	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
Anae109_2993	ENOG4105DQU	oxidoreductase, subunit beta
Anae109_2994	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
Anae109_2995	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
Anae109_2999	ENOG4105CQB	FAD linked oxidase domain protein
Anae109_3000	ENOG4107R37	Glutamate dehydrogenase
Anae109_3002	ENOG4105CSU	acyl-Coa dehydrogenase
Anae109_3005	ENOG4105BZU	Histidine kinase
Anae109_3006	ENOG4105CGD	Nad-dependent epimerase dehydratase
Anae109_3009	ENOG4107U9T	Pfam:Ribonuclease_BN
Anae109_3011	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
Anae109_3013	ENOG4105R8A	Heat shock protein
Anae109_3018	ENOG4105CV8	reductase
Anae109_3019	ENOG4105D5T	phosphonate abc transporter
Anae109_3020	ENOG4105S7S	phosphonate abc transporter
Anae109_3021	ENOG4107T9Q	phosphonate abc transporter
Anae109_3024	ENOG4105CGC	Nitrogenase cofactor biosynthesis protein NifB
Anae109_3026	ENOG4108UR2	Nitrogen fixation protein NifX
Anae109_3027	ENOG4105D0B	Nitrogenase protein alpha chain
Anae109_3028	ENOG4105CY9	nitrogenase molybdenum-iron protein beta chain
Anae109_3029	ENOG4105D0B	Nitrogenase protein alpha chain
Anae109_3032	ENOG4108JUA	Transcriptional regulator
Anae109_3033	ENOG4108K8Z	nad( )--dinitrogen-reductase ADP-d-ribosyltransferase
Anae109_3034	ENOG41065RQ	ADP-ribosylation crystallin J1
Anae109_3035	ENOG4105D4Y	metalloprotease
Anae109_3037	ENOG4105C8J	)-transporter
Anae109_3038	ENOG4105BZG	amino acid carrier protein
Anae109_3042	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Anae109_3043	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
Anae109_3045	ENOG4108JU9	GAF modulated sigma54 specific transcriptional regulator Fis family
Anae109_3047	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
Anae109_3050	ENOG4107SET	aldo keto reductase
Anae109_3051	ENOG4107GFK	fumarate
Anae109_3056	ENOG4105E90	ABC transporter
Anae109_3057	ENOG4108IJ8	ABC transporter
Anae109_3062	ENOG4108UT2	hemolysin iii
Anae109_3068	ENOG4105BZU	Histidine kinase
Anae109_3069	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Anae109_3070	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Anae109_3071	ENOG4107S9Q	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
Anae109_3080	ENOG4105VN1	Heat shock protein
Anae109_3086	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Anae109_3094	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
Anae109_3095	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Anae109_3098	ENOG4105VSH	4-oxalocrotonate tautomerase
Anae109_3099	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Anae109_3100	ENOG4105C6K	Malic enzyme
Anae109_3101	ENOG4105C0X	amino acid
Anae109_3103	ENOG4105C08	Histidine kinase
Anae109_3104	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
Anae109_3108	ENOG4107STQ	Multicopper oxidase
Anae109_3108	ENOG4107STQ	Multicopper oxidase
Anae109_3108	ENOG4107STQ	Multicopper oxidase
Anae109_3113	ENOG4105MDS	4-oxalocrotonate tautomerase
Anae109_3114	ENOG4105D9P	serine threonine protein kinase
Anae109_3122	ENOG4108JJA	ABC, transporter
Anae109_3123	ENOG4108JJA	ABC, transporter
Anae109_3125	ENOG4108DT4	serine threonine protein kinase
Anae109_3126	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Anae109_3135	ENOG4105EUB	pirin domain protein
Anae109_3139	ENOG4107QN1	sodium solute
Anae109_3146	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
Anae109_3151	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
Anae109_3154	ENOG4105KY8	Rubrerythrin
Anae109_3155	ENOG4105C9K	Endothelin-converting enzyme 1
Anae109_3158	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
Anae109_3159	ENOG4108IYU	L-aspartate oxidase
Anae109_3164	ENOG4105CD5	CoA-binding domain protein
Anae109_3165	ENOG4105C10	Electron transfer flavoprotein
Anae109_3166	ENOG4105BZJ	Electron transfer flavoprotein
Anae109_3167	ENOG4108ZX5	transcriptional regulator
Anae109_3168	ENOG4105CSU	acyl-Coa dehydrogenase
Anae109_3169	ENOG4105D5P	Methylmalonyl-coA mutase
Anae109_3170	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Anae109_3171	ENOG41089UC	methyltransferase, type 11
Anae109_3172	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
Anae109_3173	ENOG4105C2J	ABC transporter
Anae109_3174	ENOG4105UIB	(ABC) transporter
Anae109_3179	ENOG4107UFZ	Cyclic nucleotide-binding protein
Anae109_3181	ENOG4105F4G	Membrane
Anae109_3186	ENOG4105QNF	Outer membrane lipoprotein
Anae109_3188	ENOG4105I8F	Histidine kinase
Anae109_3192	ENOG4108YYC	ycei family
Anae109_3194	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
Anae109_3197	ENOG4105D63	family UPF0324
Anae109_3199	ENOG4107SUZ	Sodium/hydrogen exchanger family
Anae109_3206	ENOG4107SET	aldo keto reductase
Anae109_3207	ENOG4105DQ4	alcohol dehydrogenase
Anae109_3208	ENOG4105DQ4	alcohol dehydrogenase
Anae109_3210	ENOG4105EQ2	LysR family Transcriptional regulator
Anae109_3213	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
Anae109_3217	ENOG4108IAJ	Nad-dependent epimerase dehydratase
Anae109_3218	ENOG4105CPQ	Dehydrogenase
Anae109_3219	ENOG4105CK5	oxidoreductase
Anae109_3222	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
Anae109_3226	ENOG4105BZ1	(ABC) transporter
Anae109_3228	ENOG4106F60	Histidine kinase
Anae109_3231	ENOG4105HEI	LysR family (Transcriptional regulator
Anae109_3233	ENOG4105KIP	Thioesterase
Anae109_3234	ENOG4105C4X	radical SAM domain protein
Anae109_3235	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
Anae109_3236	ENOG4105CHH	sulfate transporter
Anae109_3244	ENOG4105NXH	GreA GreB family elongation factor
Anae109_3246	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Anae109_3247	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
Anae109_3248	ENOG4105DQE	DNA ligase
Anae109_3252	ENOG4108ZHJ	Organic hydroperoxide resistance protein
Anae109_3254	ENOG4108IND	Tetr family transcriptional regulator
Anae109_3255	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
Anae109_3258	ENOG41082J7	Rhodanese domain protein
Anae109_3259	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Anae109_3267	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
Anae109_3272	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Anae109_3275	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
Anae109_3277	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Anae109_3284	ENOG4108MCI	Transcriptional regulator, ARAC family
Anae109_3288	ENOG4105F5W	AtP-binding protein
Anae109_3304	ENOG4105C0D	helicase
Anae109_3310	ENOG4107YBY	Hydrolase
Anae109_3314	ENOG4105CV8	reductase
Anae109_3316	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Anae109_3317	ENOG4108HHA	Transketolase
Anae109_3321	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Anae109_3323	ENOG4107Y70	Heat shock protein
Anae109_3327	ENOG41080TK	Universal stress protein
Anae109_3335	ENOG4107R7Y	intracellular protease Pfpi family
Anae109_3336	ENOG4107Y70	Heat shock protein
Anae109_3343	ENOG4107RAQ	aminopeptidase
Anae109_3348	ENOG4105FRY	Dehydrogenase
Anae109_3350	ENOG4105D9P	serine threonine protein kinase
Anae109_3352	ENOG4105CSH	Transporter
Anae109_3365	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_3375	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Anae109_3380	ENOG4105C5H	ABC transporter
Anae109_3381	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
Anae109_3396	ENOG4105CUV	Homoserine Kinase
Anae109_3403	ENOG4105KCK	Peptidoglycan-associated lipoprotein
Anae109_3404	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_3405	ENOG4108JQC	penicillin-binding protein 1A
Anae109_3408	ENOG4105ES5	Histidine kinase
Anae109_3412	ENOG4105C7N	Xanthine uracil vitamin C permease
Anae109_3413	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
Anae109_3415	ENOG4107YX5	Pfam:DUF548
Anae109_3416	ENOG4108NEV	two component transcriptional regulator, LytTR family
Anae109_3417	ENOG4108HRK	Histidine kinase
Anae109_3418	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Anae109_3420	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
Anae109_3421	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Anae109_3422	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Anae109_3424	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Anae109_3425	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
Anae109_3426	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
Anae109_3427	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
Anae109_3430	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
Anae109_3433	ENOG4105CZX	twitching motility protein
Anae109_3435	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Anae109_3437	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Anae109_3438	ENOG4107VAM	peptidase, m28
Anae109_3442	ENOG4105C34	Pseudouridine synthase
Anae109_3448	ENOG4105E4C	Lytic transglycosylase catalytic
Anae109_3449	ENOG4105ECY	inositol monophosphatase
Anae109_3455	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Anae109_3458	ENOG4105DFU	Cell wall formation (By similarity)
Anae109_3460	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
Anae109_3461	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
Anae109_3462	ENOG4105C02	permease
Anae109_3463	ENOG4108V1T	peptidylprolyl cis-trans isomerase
Anae109_3464	ENOG4108SHQ	Glutathione S-transferase
Anae109_3473	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Anae109_3479	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
Anae109_3484	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
Anae109_3487	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Anae109_3488	ENOG41080XQ	Signal transduction protein with cbs domains
Anae109_3496	ENOG4105C1J	atp-dependent rna helicase
Anae109_3497	ENOG4105NBK	UPF0345 protein
Anae109_3513	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
Anae109_3518	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
Anae109_3520	ENOG4105DPX	Hydrogenase, large subunit
Anae109_3521	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
Anae109_3522	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Anae109_3523	ENOG4105E3S	small subunit
Anae109_3524	ENOG4105CJ5	hydrogenase 2 b cytochrome subunit
Anae109_3527	ENOG4105ER2	Ompa motb domain protein
Anae109_3532	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Anae109_3533	ENOG4105CBS	Chea signal transduction histidine kinase
Anae109_3535	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Anae109_3536	ENOG4108W2P	Methyl-accepting chemotaxis
Anae109_3543	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
Anae109_3545	ENOG4105CGZ	zinc metallopeptidase
Anae109_3546	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Anae109_3549	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
Anae109_3552	ENOG4105C0B	DNA polymerase III (alpha subunit)
Anae109_3555	ENOG4108S01	response regulator
Anae109_3556	ENOG4105C7B	Threonine dehydratase
Anae109_3558	ENOG4105D9P	serine threonine protein kinase
Anae109_3561	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Anae109_3562	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
Anae109_3565	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Anae109_3566	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
Anae109_3567	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
Anae109_3575	ENOG4105EHG	Permease protein
Anae109_3576	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
Anae109_3578	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
Anae109_3579	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
Anae109_3583	ENOG4105BZU	Histidine kinase
Anae109_3587	ENOG4108WBT	adenosyltransferase
Anae109_3589	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
Anae109_3590	ENOG4105C5X	domain protein
Anae109_3591	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
Anae109_3593	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
Anae109_3596	ENOG4108IUE	nitrate reductase beta subunit
Anae109_3598	ENOG4105DQQ	Major facilitator superfamily MFS_1
Anae109_3603	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
Anae109_3604	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
Anae109_3608	ENOG4105C6T	cysteine synthase
Anae109_3609	ENOG4105C6T	cysteine synthase
Anae109_3613	ENOG4105DHU	Bile acid
Anae109_3614	ENOG4105EUB	pirin domain protein
Anae109_3617	ENOG4105DC7	peptidase M24
Anae109_3618	ENOG4105QUH	Domain of unknown function (DUF2088)
Anae109_3622	ENOG4105WH9	RNA polymerase
Anae109_3625	ENOG4105WH9	RNA polymerase
Anae109_3626	ENOG4105E0X	reductase
Anae109_3627	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Anae109_3628	ENOG4105EQW	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
Anae109_3631	ENOG4105M3Z	response regulator
Anae109_3632	ENOG4105BZU	Histidine kinase
Anae109_3635	ENOG4108YZA	Nitrogen regulatory protein pii
Anae109_3637	ENOG41088YS	Glycosyl transferase (Group 1
Anae109_3639	ENOG4108YYC	ycei family
Anae109_3640	ENOG4105CC0	LysR family Transcriptional regulator
Anae109_3642	ENOG4108UXE	Protein tyrosine phosphatase
Anae109_3643	ENOG4105D6J	arsenicaL-resistance protein
Anae109_3653	ENOG4108RE9	Phosphodiesterase
Anae109_3664	ENOG4108KB2	LysR family Transcriptional regulator
Anae109_3668	ENOG4105WH1	Two component transcriptional regulator luxr family
Anae109_3669	ENOG4107TTQ	Alpha beta hydrolase fold
Anae109_3672	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Anae109_3674	ENOG4105XUP	Phage derived protein Gp49-like (DUF891)
Anae109_3684	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
Anae109_3686	ENOG4105E4C	Lytic transglycosylase catalytic
Anae109_3687	ENOG4108IYU	L-aspartate oxidase
Anae109_3689	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Anae109_3699	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
Anae109_3702	ENOG41072GX	Peptidase M22 Glycoprotease
Anae109_3703	ENOG4105DZP	Membrane-associated zinc metalloprotease
Anae109_3706	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Anae109_3707	ENOG4108PBA	serine threonine protein kinase
Anae109_3711	ENOG41084BP	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
Anae109_3714	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Anae109_3715	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Anae109_3721	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Anae109_3723	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
Anae109_3724	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
Anae109_3725	ENOG4108JU7	Transcriptional regulator
Anae109_3735	ENOG41067MG	lrgb family
Anae109_3743	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
Anae109_3745	ENOG4108I62	cina-like protein
Anae109_3750	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Anae109_3751	ENOG4105C0P	Mg chelatase subunit ChlI
Anae109_3754	ENOG4107S9F	NmrA family
Anae109_3755	ENOG4105E50	uracil-dna glycosylase
Anae109_3758	ENOG4105CXV	gliding motility protein
Anae109_3760	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Anae109_3761	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
Anae109_3762	ENOG4105C6E	dna polymerase iii
Anae109_3763	ENOG4108Z6B	deaminase
Anae109_3766	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
Anae109_3767	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Anae109_3769	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
Anae109_3770	ENOG4105UYK	outer membrane protein a
Anae109_3772	ENOG4105Y3U	Transglycosylase-associated protein
Anae109_3775	ENOG4105D9P	serine threonine protein kinase
Anae109_3776	ENOG4105F8J	Adenylate Guanylate cyclase
Anae109_3777	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_3779	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
Anae109_3780	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Anae109_3781	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Anae109_3784	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Anae109_3785	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Anae109_3786	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Anae109_3792	ENOG4105DAP	Nicotinate phosphoribosyltransferase
Anae109_3793	ENOG4107QM5	aconitate hydratase
Anae109_3795	ENOG4105BZU	Histidine kinase
Anae109_3799	ENOG4105DR5	peptidase
Anae109_3801	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Anae109_3803	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
Anae109_3807	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Anae109_3808	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
Anae109_3809	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
Anae109_3813	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Anae109_3814	ENOG4105BZU	Histidine kinase
Anae109_3815	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Anae109_3817	ENOG4108ZF3	Phosphatase
Anae109_3828	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Anae109_3832	ENOG4107QN1	sodium solute
Anae109_3836	ENOG4107QN1	sodium solute
Anae109_3837	ENOG4105C8Q	Methyl-accepting chemotaxis
Anae109_3839	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
Anae109_3844	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
Anae109_3845	ENOG4105C28	cystathionine
Anae109_3847	ENOG4105EHM	Aminoglycoside phosphotransferase
Anae109_3848	ENOG4105DSQ	Nitric oxide reductase
Anae109_3849	ENOG4105C8F	Beta-lactamase domain protein
Anae109_3851	ENOG4105DR4	Methyltransferase
Anae109_3853	ENOG4105BZU	Histidine kinase
Anae109_3855	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
Anae109_3856	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
Anae109_3857	ENOG4105BZU	Histidine kinase
Anae109_3858	ENOG4108SPH	protein kinase (EC 2.7.11.1)
Anae109_3860	ENOG4105E39	Enoyl-CoA hydratase
Anae109_3861	ENOG4106063	Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit
Anae109_3862	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
Anae109_3865	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
Anae109_3868	ENOG4107UWC	ABC, transporter
Anae109_3869	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
Anae109_3874	ENOG4108V6E	Cell division protein mraZ
Anae109_3876	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Anae109_3878	ENOG4105CJN	penicillin-binding protein
Anae109_3879	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Anae109_3880	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
Anae109_3881	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Anae109_3882	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Anae109_3884	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Anae109_3885	ENOG4105DFU	Cell wall formation (By similarity)
Anae109_3886	ENOG4105D4A	Cell wall formation (By similarity)
Anae109_3887	ENOG4105CPF	Cell wall formation (By similarity)
Anae109_3891	ENOG4107STQ	Multicopper oxidase
Anae109_3893	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
Anae109_3894	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Anae109_3904	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Anae109_3907	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
Anae109_3909	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
Anae109_3910	ENOG4105VY0	Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters (By similarity)
Anae109_3916	ENOG4105CN1	protease
Anae109_3919	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
Anae109_3924	ENOG41090R7	Ferric uptake
Anae109_3925	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
Anae109_3926	ENOG4108UUM	single-stranded DNA-binding protein
Anae109_3927	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Anae109_3933	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
Anae109_3935	ENOG4105W5Q	DNA repair protein (RadC
Anae109_3937	ENOG4105W5Q	DNA repair protein (RadC
Anae109_3938	ENOG4105W5Q	DNA repair protein (RadC
Anae109_3942	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
Anae109_3943	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
Anae109_3944	ENOG4105CHM	Aminotransferase
Anae109_3945	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
Anae109_3948	ENOG4108Q9H	CobQ/CobB/MinD/ParA nucleotide binding domain
Anae109_3953	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
Anae109_3954	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
Anae109_3956	ENOG4105ETX	regulatoR
Anae109_3957	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
Anae109_3958	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
Anae109_3959	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
Anae109_3974	ENOG4105EMU	Dehydrogenase
Anae109_3978	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Anae109_3980	ENOG4108KU3	Integrase
Anae109_3989	ENOG4105C0D	helicase
Anae109_3992	ENOG4105C0D	helicase
Anae109_3993	ENOG4105CFI	type iii restriction protein res subunit
Anae109_3996	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
Anae109_3997	ENOG4105GRF	N-glycosylase DNA lyase
Anae109_4022	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Anae109_4025	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Anae109_4026	ENOG4105E2V	Glycosyltransferase 36
Anae109_4029	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
Anae109_4031	ENOG41080BE	Methyl-accepting chemotaxis sensory transducer
Anae109_4035	ENOG41061DF	Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P (By similarity)
Anae109_4040	ENOG4105K63	Thioredoxin
Anae109_4042	ENOG4105VEQ	Cold shock protein
Anae109_4046	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Anae109_4047	ENOG4108XNJ	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
Anae109_4048	ENOG4108YZ9	Urea amidohydrolase subunit gamma
Anae109_4049	ENOG4105CQM	Urea amidohydrolase subunit alpha
Anae109_4050	ENOG4107YEM	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
Anae109_4051	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
Anae109_4052	ENOG4108R3E	Dna-3-methyladenine glycosylase i
Anae109_4054	ENOG4105BZU	Histidine kinase
Anae109_4057	ENOG4105C0D	helicase
Anae109_4061	ENOG4107QP3	malate synthase g
Anae109_4062	ENOG4105C5H	ABC transporter
Anae109_4064	ENOG4108DT4	serine threonine protein kinase
Anae109_4069	ENOG4107YZX	Universal stress protein
Anae109_4070	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
Anae109_4073	ENOG4108UQY	Iron-storage protein
Anae109_4074	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
Anae109_4075	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Anae109_4079	ENOG4105EWU	Squalene--hopene cyclase
Anae109_4080	ENOG4105FE1	phytoene synthase
Anae109_4081	ENOG4105CX0	fumarate reductase succinate dehydrogenase flavoprotein domain protein
Anae109_4082	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
Anae109_4085	ENOG4105C28	cystathionine
Anae109_4086	ENOG4107S2Z	UPF0761 membrane protein
Anae109_4089	ENOG4105D1S	lipid A biosynthesis
Anae109_4092	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
Anae109_4093	ENOG4105D8K	carboxyl transferase
Anae109_4097	ENOG4105D0M	Protease HtpX homolog
Anae109_4104	ENOG4105CE1	Ferrous iron transport protein b
Anae109_4105	ENOG4105CE1	Ferrous iron transport protein b
Anae109_4109	ENOG4105D3S	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
Anae109_4110	ENOG4108J2R	molybdopterin oxidoreductase
Anae109_4117	ENOG4105VEQ	Cold shock protein
Anae109_4121	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
Anae109_4122	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Anae109_4125	ENOG4107QIV	Cytochrome c biogenesis protein
Anae109_4127	ENOG4107QSN	dihydrolipoamide acetyltransferase
Anae109_4128	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
Anae109_4139	ENOG4105CGK	Exodeoxyribonuclease III
Anae109_4141	ENOG4105BZU	Histidine kinase
Anae109_4143	ENOG410834F	Transcriptional regulator
Anae109_4148	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
Anae109_4149	ENOG4107SW0	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Anae109_4150	ENOG4105EM7	Selenocysteine-specific translation elongation factor
Anae109_4151	ENOG4105BZU	Histidine kinase
Anae109_4155	ENOG4105C8S	subunit m
Anae109_4156	ENOG4105D65	subunit l
Anae109_4157	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
Anae109_4160	ENOG4105BZU	Histidine kinase
Anae109_4162	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
Anae109_4163	ENOG4105CHU	acetyl-coa acetyltransferase
Anae109_4166	ENOG4105CJ1	ABC, transporter
Anae109_4169	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
Anae109_4173	ENOG4105DP0	ferredoxin-NADP reductase
Anae109_4174	ENOG4105D9P	serine threonine protein kinase
Anae109_4180	ENOG4105DGW	oligopeptidase A
Anae109_4183	ENOG4107RCI	amp-dependent synthetase and ligase
Anae109_4184	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
Anae109_4187	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Anae109_4190	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
Anae109_4191	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Anae109_4194	ENOG4105EAH	synthase
Anae109_4198	ENOG4105CKK	Glycosyl transferase, family 2
Anae109_4203	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
Anae109_4204	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Anae109_4205	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
Anae109_4206	ENOG4105DVY	radical SAM domain protein
Anae109_4207	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
Anae109_4208	ENOG4107SYB	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
Anae109_4213	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Anae109_4214	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Anae109_4215	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Anae109_4216	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
Anae109_4219	ENOG4105VTR	Integrase
Anae109_4223	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
Anae109_4239	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
Anae109_4240	ENOG4105CAY	ferredoxin--nadp reductase
Anae109_4242	ENOG4108JUA	Transcriptional regulator
Anae109_4244	ENOG4105D5Q	Arginine ornithine antiporter
Anae109_4245	ENOG4105CHM	Aminotransferase
Anae109_4250	ENOG4105BZU	Histidine kinase
Anae109_4251	ENOG4105GR3	Histidine kinase
Anae109_4252	ENOG4108KXV	response regulator
Anae109_4253	ENOG4105CYP	glycoside hydrolase, family
Anae109_4254	ENOG4105SXS	Protein of unknown function (DUF456)
Anae109_4256	ENOG4105BZU	Histidine kinase
Anae109_4257	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_4258	ENOG4108TQ9	Histidine kinase
Anae109_4259	ENOG41067XB	TonB family
Anae109_4264	ENOG4108IJF	Heavy metal efflux pump, CzcA
Anae109_4267	ENOG4105E3B	Multicopper oxidase
Anae109_4269	ENOG4105C01	Dihydroxy-acid dehydratase
Anae109_4274	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Anae109_4277	ENOG4105C1G	acyl-Coa dehydrogenase
Anae109_4285	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Anae109_4290	ENOG4105E2K	Glycosyl transferase (Group 1
Anae109_4296	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Anae109_4298	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Anae109_4299	ENOG4105C3F	Signal peptidase i
Anae109_4301	ENOG4107QIM	DNA ligase
Anae109_4302	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
Anae109_4310	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
Anae109_4311	ENOG4105MS2	ribosomal subunit Interface protein
Anae109_4312	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Anae109_4313	ENOG4108IUZ	ABC transporter
Anae109_4316	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
Anae109_4318	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
Anae109_4319	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
Anae109_4321	ENOG4105C34	Pseudouridine synthase
Anae109_4325	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
Anae109_4326	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Anae109_4327	ENOG4105K46	50S ribosomal protein l27
Anae109_4334	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
Anae109_4336	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Anae109_4339	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Anae109_4343	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
Anae109_4346	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Anae109_4347	ENOG4107YX3	NADH dehydrogenase subunit j
Anae109_4350	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
Anae109_4354	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
Anae109_4355	ENOG4107R72	Ceramidase
Anae109_4361	ENOG4105BZU	Histidine kinase
Anae109_4362	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
Anae109_4365	ENOG4105BZU	Histidine kinase
Anae109_4369	ENOG4105C98	muts2 protein
Anae109_4370	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Anae109_4376	ENOG4105BZU	Histidine kinase
Anae109_4378	ENOG4107QXV	Phosphate transporter
Anae109_4379	ENOG4108QEV	ribosomal RNA large subunit methyltransferase N
Anae109_4380	ENOG4108VX5	3-methyladenine DNA glycosylase
Anae109_4383	ENOG4105CA9	Pyruvate kinase
Anae109_4385	ENOG4108JMX	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
Anae109_4391	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Anae109_4395	ENOG4108TQ9	Histidine kinase
Anae109_4397	ENOG4108YZA	Nitrogen regulatory protein pii
Anae109_4398	ENOG4105BZU	Histidine kinase
Anae109_4399	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
Anae109_4403	ENOG4107RIQ	Sulfate adenylate transferase
Anae109_4404	ENOG4105CHR	reductase
Anae109_4408	ENOG4108KPJ	rna polymerase sigma factor
Anae109_4410	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
Anae109_4412	ENOG4108IV0	ABC, transporter
Anae109_4413	ENOG4105C0Z	ABC transporter
Anae109_4414	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
Anae109_4415	ENOG4105C32	Amino acid ABC transporter (Permease)
Anae109_4417	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
Anae109_4419	ENOG4105D17	glycoside hydrolase, family 3 domain protein
Anae109_4422	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
Anae109_4425	ENOG4105EMN	RNA polymerase sigma factor
Anae109_4429	ENOG4105DAY	polysaccharide export protein
Anae109_4431	ENOG4105BZ1	(ABC) transporter
Anae109_4433	ENOG4105ESV	Glycosyl transferase, family 4
Anae109_4435	ENOG4105Q84	sucrose synthase
Anae109_4436	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Anae109_4441	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
Anae109_4444	ENOG4105CKK	Glycosyl transferase, family 2
Anae109_4447	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
Anae109_4451	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
Anae109_4452	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
Anae109_4457	ENOG4105BZU	Histidine kinase
Anae109_4458	ENOG4105C8M	UPF0272 protein
Anae109_4459	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
Anae109_4461	ENOG4105CBS	Chea signal transduction histidine kinase
Anae109_4462	ENOG4107YTP	response regulator receiver protein
Anae109_4463	ENOG4108V3W	Chemotaxis protein, CheW
Anae109_4464	ENOG4108NVR	Methyl-accepting chemotaxis
Anae109_4465	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
Anae109_4466	ENOG4105BZU	Histidine kinase
Anae109_4467	ENOG4105CXV	gliding motility protein
Anae109_4468	ENOG4105DVT	helicase
Anae109_4473	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Anae109_4474	ENOG4105CFG	Acts as a chaperone (By similarity)
Anae109_4475	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Anae109_4476	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
Anae109_4478	ENOG4108JA2	transcriptioN-repair coupling factor
Anae109_4479	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
Anae109_4480	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
Anae109_4481	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
Anae109_4482	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
Anae109_4484	ENOG4105C3G	gtp-binding protein
Anae109_4485	ENOG4108KJP	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Anae109_4487	ENOG4107WJT	it plays a direct role in the translocation of protons across the membrane (By similarity)
Anae109_4491	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
Anae109_4493	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Anae109_4494	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Anae109_4495	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
Anae109_4496	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Anae109_4497	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Anae109_4498	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Anae109_4499	ENOG4105VN1	Heat shock protein
Anae109_4501	ENOG4105FA0	parb-like partition protein
Anae109_4502	ENOG4107QJE	Chromosome Partitioning Protein
Anae109_4504	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Anae109_4506	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Anae109_4507	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Anae109_4508	ENOG41084M4	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)