locus-tag	class	description
AnaeK_0001	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AnaeK_0005	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AnaeK_0008	COG0247	lactate metabolic process
AnaeK_0008	COG2181	nitrate reductase activity
AnaeK_0011	COG0189	ligase activity
AnaeK_0012	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AnaeK_0013	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AnaeK_0014	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AnaeK_0023	COG3852	Histidine kinase
AnaeK_0026	COG0442	prolyl-tRNA aminoacylation
AnaeK_0029	COG2249	NAD(P)H dehydrogenase (quinone) activity
AnaeK_0034	COG1028	Short-chain dehydrogenase reductase Sdr
AnaeK_0037	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AnaeK_0040	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AnaeK_0042	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AnaeK_0045	COG0280	phosphate acetyltransferase
AnaeK_0046	COG3426	butyrate kinase activity
AnaeK_0047	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AnaeK_0049	COG0586	Pfam SNARE associated Golgi protein
AnaeK_0052	COG2086	electron transfer activity
AnaeK_0054	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AnaeK_0055	COG0861	Integral membrane protein TerC family
AnaeK_0060	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AnaeK_0060	COG1793	dna ligase
AnaeK_0061	COG0564	pseudouridine synthase activity
AnaeK_0065	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AnaeK_0066	COG0805	protein transport
AnaeK_0068	COG0183	Belongs to the thiolase family
AnaeK_0072	COG1032	radical SAM domain protein
AnaeK_0075	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
AnaeK_0081	COG0352	thiamine-phosphate diphosphorylase activity
AnaeK_0082	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
AnaeK_0083	COG0351	phosphomethylpyrimidine kinase
AnaeK_0083	COG0352	thiamine-phosphate diphosphorylase activity
AnaeK_0083	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AnaeK_0085	COG0305	Participates in initiation and elongation during chromosome replication
AnaeK_0089	COG1346	cytolysis
AnaeK_0091	COG0583	DNA-binding transcription factor activity
AnaeK_0092	COG1410	methionine synthase
AnaeK_0092	COG0646	methionine synthase
AnaeK_0096	COG0433	COG0433 Predicted ATPase
AnaeK_0105	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AnaeK_0106	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AnaeK_0108	COG0745	RESPONSE REGULATOR receiver
AnaeK_0108	COG3706	GGDEF domain
AnaeK_0109	COG0612	Peptidase, M16
AnaeK_0110	COG0612	Peptidase, M16
AnaeK_0113	COG2204	response regulator
AnaeK_0114	COG3852	Histidine kinase
AnaeK_0119	COG1077	Cell shape determining protein MreB Mrl
AnaeK_0120	COG1077	Cell shape determining protein MreB Mrl
AnaeK_0121	COG1506	peptidase
AnaeK_0121	COG0823	Involved in the tonB-independent uptake of proteins
AnaeK_0125	COG0360	Binds together with S18 to 16S ribosomal RNA
AnaeK_0128	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AnaeK_0133	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
AnaeK_0134	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
AnaeK_0139	COG3706	GGDEF domain
AnaeK_0151	COG2204	response regulator
AnaeK_0153	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AnaeK_0155	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
AnaeK_0155	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
AnaeK_0158	COG3716	PTS system mannose fructose sorbose family IID component
AnaeK_0159	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
AnaeK_0163	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AnaeK_0166	COG0662	Cupin 2, conserved barrel domain protein
AnaeK_0166	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AnaeK_0168	COG1940	carbohydrate kinase activity
AnaeK_0168	COG1846	Transcriptional regulator
AnaeK_0180	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AnaeK_0188	COG3138	arginine N-succinyltransferase
AnaeK_0189	COG1490	D-aminoacyl-tRNA deacylase activity
AnaeK_0190	COG0537	adenosine 5'-monophosphoramidase activity
AnaeK_0200	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AnaeK_0201	COG0463	Glycosyl transferase, family 2
AnaeK_0213	COG1612	heme a metabolic process
AnaeK_0213	COG0109	protoheme IX farnesyltransferase activity
AnaeK_0219	COG2814	Major facilitator Superfamily
AnaeK_0224	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AnaeK_0227	COG2226	methyltransferase
AnaeK_0228	COG0697	spore germination
AnaeK_0230	COG1013	pyruvate-flavodoxin oxidoreductase activity
AnaeK_0230	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AnaeK_0230	COG0674	pyruvate-flavodoxin oxidoreductase activity
AnaeK_0239	COG1309	transcriptional regulator
AnaeK_0246	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
AnaeK_0251	COG3070	regulator of competence-specific genes
AnaeK_0254	COG1297	OPT oligopeptide transporter protein
AnaeK_0255	COG0745	RESPONSE REGULATOR receiver
AnaeK_0256	COG2264	protein methyltransferase activity
AnaeK_0257	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AnaeK_0260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AnaeK_0262	COG1278	Cold shock
AnaeK_0265	COG0204	Acyl-transferase
AnaeK_0267	COG5002	protein histidine kinase activity
AnaeK_0268	COG0439	Biotin carboxylase
AnaeK_0269	COG5016	pyruvate
AnaeK_0269	COG0511	ligase activity, forming carbon-carbon bonds
AnaeK_0271	COG0484	heat shock protein binding
AnaeK_0276	COG0564	pseudouridine synthase activity
AnaeK_0277	COG0848	biopolymer transport protein
AnaeK_0279	COG0811	peptide transport
AnaeK_0284	COG0052	Belongs to the universal ribosomal protein uS2 family
AnaeK_0287	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AnaeK_0287	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AnaeK_0288	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AnaeK_0289	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AnaeK_0290	COG0617	tRNA 3'-terminal CCA addition
AnaeK_0291	COG0528	UMP kinase activity
AnaeK_0296	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AnaeK_0296	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AnaeK_0302	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AnaeK_0303	COG2062	phosphohistidine phosphatase, SixA
AnaeK_0305	COG1640	4-alpha-glucanotransferase
AnaeK_0306	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AnaeK_0310	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AnaeK_0312	COG4191	Histidine kinase
AnaeK_0314	COG2839	Protein conserved in bacteria
AnaeK_0321	COG1942	4-Oxalocrotonate Tautomerase
AnaeK_0323	COG0583	DNA-binding transcription factor activity
AnaeK_0333	COG3291	Pkd domain containing protein
AnaeK_0333	COG4412	M6 family metalloprotease domain protein
AnaeK_0335	COG0308	aminopeptidase N
AnaeK_0336	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AnaeK_0339	COG2151	metal-sulfur cluster biosynthetic enzyme
AnaeK_0343	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AnaeK_0350	COG4206	TonB-dependent receptor
AnaeK_0354	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AnaeK_0356	COG0840	transmembrane signaling receptor activity
AnaeK_0363	COG0693	protein deglycase activity
AnaeK_0367	COG2267	carboxylic ester hydrolase activity
AnaeK_0369	COG2855	membrane
AnaeK_0370	COG0583	DNA-binding transcription factor activity
AnaeK_0373	COG2205	protein histidine kinase activity
AnaeK_0374	COG3239	Fatty acid desaturase
AnaeK_0375	COG3218	ABC-type transport auxiliary lipoprotein component
AnaeK_0377	COG1127	ABC transporter
AnaeK_0378	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AnaeK_0386	COG1024	Enoyl-CoA hydratase
AnaeK_0386	COG1250	3-hydroxyacyl-CoA dehydrogenase
AnaeK_0387	COG0183	Belongs to the thiolase family
AnaeK_0388	COG1960	acyl-CoA dehydrogenase activity
AnaeK_0393	COG2890	protein-(glutamine-N5) methyltransferase activity
AnaeK_0395	COG2205	protein histidine kinase activity
AnaeK_0395	COG0784	Response regulator, receiver
AnaeK_0398	COG0402	S-adenosylhomocysteine deaminase activity
AnaeK_0399	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AnaeK_0400	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AnaeK_0401	COG0163	prenyltransferase activity
AnaeK_0402	COG2226	methyltransferase
AnaeK_0403	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AnaeK_0405	COG0612	Peptidase, M16
AnaeK_0413	COG0542	response to heat
AnaeK_0414	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AnaeK_0417	COG0318	PFAM AMP-dependent synthetase and ligase
AnaeK_0429	COG1234	tRNA 3'-trailer cleavage
AnaeK_0430	COG1741	Belongs to the pirin family
AnaeK_0432	COG1131	(ABC) transporter
AnaeK_0435	COG0183	Belongs to the thiolase family
AnaeK_0436	COG1250	3-hydroxyacyl-CoA dehydrogenase
AnaeK_0436	COG1024	Enoyl-CoA hydratase
AnaeK_0438	COG5002	protein histidine kinase activity
AnaeK_0439	COG0745	RESPONSE REGULATOR receiver
AnaeK_0441	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AnaeK_0446	COG3852	Histidine kinase
AnaeK_0448	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AnaeK_0449	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
AnaeK_0451	COG1088	dTDP-glucose 4,6-dehydratase activity
AnaeK_0452	COG0204	Acyl-transferase
AnaeK_0454	COG1846	Transcriptional regulator
AnaeK_0457	COG3706	GGDEF domain
AnaeK_0468	COG0420	3'-5' exonuclease activity
AnaeK_0475	COG0577	efflux transmembrane transporter activity
AnaeK_0475	COG1136	(ABC) transporter
AnaeK_0481	COG1309	transcriptional regulator
AnaeK_0483	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AnaeK_0485	COG0667	Aldo Keto reductase
AnaeK_0489	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AnaeK_0489	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AnaeK_0490	COG3639	organic phosphonate transmembrane transporter activity
AnaeK_0491	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AnaeK_0497	COG0439	Biotin carboxylase
AnaeK_0501	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AnaeK_0502	COG3875	lactate racemase activity
AnaeK_0508	COG0298	carbon dioxide binding
AnaeK_0509	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AnaeK_0511	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
AnaeK_0512	COG5557	Pfam Polysulphide reductase, NrfD
AnaeK_0513	COG0437	4 iron, 4 sulfur cluster binding
AnaeK_0514	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AnaeK_0520	COG1285	pathogenesis
AnaeK_0521	COG2119	membrane
AnaeK_0526	COG1122	ATPase activity
AnaeK_0528	COG0310	cobalt ion transport
AnaeK_0531	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AnaeK_0531	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AnaeK_0536	COG2205	protein histidine kinase activity
AnaeK_0539	COG5002	protein histidine kinase activity
AnaeK_0540	COG0493	'glutamate synthase
AnaeK_0540	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
AnaeK_0542	COG2133	pyrroloquinoline quinone binding
AnaeK_0543	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AnaeK_0549	COG1538	Outer membrane efflux protein
AnaeK_0550	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AnaeK_0552	COG1309	transcriptional regulator
AnaeK_0553	COG0366	Alpha amylase catalytic
AnaeK_0555	COG0596	Alpha beta hydrolase
AnaeK_0557	COG2832	Protein of unknown function (DUF454)
AnaeK_0562	COG0671	phosphoesterase, PA-phosphatase related
AnaeK_0563	COG1752	Esterase of the alpha-beta hydrolase superfamily
AnaeK_0565	COG0436	Aminotransferase
AnaeK_0567	COG3047	cAMP biosynthetic process
AnaeK_0568	COG4191	Histidine kinase
AnaeK_0570	COG1122	ATPase activity
AnaeK_0571	COG1268	BioY protein
AnaeK_0572	COG0400	carboxylic ester hydrolase activity
AnaeK_0577	COG0667	Aldo Keto reductase
AnaeK_0583	COG0583	DNA-binding transcription factor activity
AnaeK_0585	COG1028	Short-chain dehydrogenase reductase Sdr
AnaeK_0590	COG1028	Short-chain dehydrogenase reductase Sdr
AnaeK_0591	COG0583	DNA-binding transcription factor activity
AnaeK_0601	COG3177	Filamentation induced by cAMP protein fic
AnaeK_0602	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AnaeK_0604	COG1228	amidohydrolase
AnaeK_0605	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AnaeK_0606	COG2204	response regulator
AnaeK_0611	COG0612	Peptidase, M16
AnaeK_0612	COG5002	protein histidine kinase activity
AnaeK_0622	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AnaeK_0623	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AnaeK_0626	COG4232	protein-disulfide reductase activity
AnaeK_0629	COG0316	Belongs to the HesB IscA family
AnaeK_0630	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
AnaeK_0631	COG0443	Heat shock 70 kDa protein
AnaeK_0634	COG2201	protein-glutamate methylesterase activity
AnaeK_0636	COG0835	chemotaxis
AnaeK_0637	COG0643	Histidine kinase
AnaeK_0637	COG2198	Histidine kinase
AnaeK_0638	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AnaeK_0640	COG0745	RESPONSE REGULATOR receiver
AnaeK_0643	COG0745	RESPONSE REGULATOR receiver
AnaeK_0648	COG2201	protein-glutamate methylesterase activity
AnaeK_0650	COG0784	Response regulator, receiver
AnaeK_0651	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
AnaeK_0652	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AnaeK_0654	COG0295	cytidine deaminase activity
AnaeK_0655	COG0196	riboflavin kinase activity
AnaeK_0656	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AnaeK_0659	COG3852	Histidine kinase
AnaeK_0669	COG4968	Prepilin-type N-terminal cleavage methylation domain
AnaeK_0670	COG1131	(ABC) transporter
AnaeK_0671	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
AnaeK_0672	COG4191	Histidine kinase
AnaeK_0673	COG2204	response regulator
AnaeK_0675	COG0849	cell division
AnaeK_0682	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AnaeK_0683	COG0511	ligase activity, forming carbon-carbon bonds
AnaeK_0684	COG0439	Biotin carboxylase
AnaeK_0686	COG3267	Type II secretory pathway component ExeA
AnaeK_0686	COG3409	Peptidoglycan-binding domain 1 protein
AnaeK_0689	COG2217	Heavy metal translocating P-type atpase
AnaeK_0698	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
AnaeK_0700	COG2884	Cell division ATP-binding protein ftsE
AnaeK_0701	COG2177	Part of the ABC transporter FtsEX involved in
AnaeK_0702	COG4942	peptidase
AnaeK_0703	COG0793	Belongs to the peptidase S41A family
AnaeK_0704	COG1215	transferase activity, transferring glycosyl groups
AnaeK_0706	COG0546	phosphoglycolate phosphatase activity
AnaeK_0707	COG0552	protein localization to endoplasmic reticulum
AnaeK_0708	COG1196	nuclear chromosome segregation
AnaeK_0709	COG3290	protein histidine kinase activity
AnaeK_0709	COG0840	transmembrane signaling receptor activity
AnaeK_0716	COG2165	general secretion pathway protein
AnaeK_0719	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AnaeK_0720	COG1450	Type ii and iii secretion system protein
AnaeK_0724	COG0254	rRNA binding
AnaeK_0725	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AnaeK_0729	COG1254	Belongs to the acylphosphatase family
AnaeK_0731	COG1530	ribonuclease E activity
AnaeK_0731	COG1530	ribonuclease E activity
AnaeK_0732	COG1295	ribonuclease BN
AnaeK_0733	COG0776	regulation of translation
AnaeK_0734	COG4789	Type iii secretion
AnaeK_0735	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AnaeK_0737	COG4794	Type iii secretion
AnaeK_0747	COG2197	response regulator
AnaeK_0748	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AnaeK_0750	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AnaeK_0752	COG0107	imidazoleglycerol-phosphate synthase activity
AnaeK_0760	COG0328	RNA-DNA hybrid ribonuclease activity
AnaeK_0760	COG0406	alpha-ribazole phosphatase activity
AnaeK_0761	COG1584	GPR1 FUN34 yaaH family protein
AnaeK_0762	COG0242	peptide deformylase activity
AnaeK_0764	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AnaeK_0767	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AnaeK_0768	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AnaeK_0769	COG0497	DNA recombination
AnaeK_0770	COG0631	protein serine/threonine phosphatase activity
AnaeK_0771	COG0739	heme binding
AnaeK_0773	COG0653	protein targeting
AnaeK_0778	COG1203	CRISPR-associated helicase, Cas3
AnaeK_0784	COG1518	maintenance of DNA repeat elements
AnaeK_0789	COG1595	DNA-templated transcription, initiation
AnaeK_0794	COG0628	permease
AnaeK_0797	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AnaeK_0799	COG0739	heme binding
AnaeK_0803	COG1881	PFAM PEBP family protein
AnaeK_0806	COG0348	domain, Protein
AnaeK_0808	COG0589	response to stress
AnaeK_0813	COG0247	lactate metabolic process
AnaeK_0816	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AnaeK_0824	COG0745	RESPONSE REGULATOR receiver
AnaeK_0826	COG1253	flavin adenine dinucleotide binding
AnaeK_0828	COG2264	protein methyltransferase activity
AnaeK_0830	COG0508	dehydrogenase complex catalyzes the overall conversion of
AnaeK_0835	COG1643	Atp-dependent helicase
AnaeK_0836	COG0071	Belongs to the small heat shock protein (HSP20) family
AnaeK_0838	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
AnaeK_0842	COG1595	DNA-templated transcription, initiation
AnaeK_0844	COG0437	4 iron, 4 sulfur cluster binding
AnaeK_0851	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
AnaeK_0856	COG0028	Belongs to the TPP enzyme family
AnaeK_0857	COG4948	Mandelate Racemase Muconate Lactonizing
AnaeK_0858	COG0277	FAD linked oxidase domain protein
AnaeK_0858	COG0247	lactate metabolic process
AnaeK_0859	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
AnaeK_0861	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AnaeK_0864	COG1793	dna ligase
AnaeK_0865	COG0067	glutamate synthase
AnaeK_0865	COG0070	glutamate synthase
AnaeK_0865	COG0069	glutamate synthase activity
AnaeK_0866	COG0493	'glutamate synthase
AnaeK_0869	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AnaeK_0871	COG0437	4 iron, 4 sulfur cluster binding
AnaeK_0874	COG3973	AAA domain
AnaeK_0875	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
AnaeK_0876	COG0488	(ABC) transporter
AnaeK_0877	COG1012	belongs to the aldehyde dehydrogenase family
AnaeK_0880	COG4191	Histidine kinase
AnaeK_0881	COG1131	(ABC) transporter
AnaeK_0882	COG0842	Transport permease protein
AnaeK_0884	COG0514	ATP-dependent DNA helicase (RecQ)
AnaeK_0887	COG4681	YaeQ
AnaeK_0889	COG0719	Fe-S assembly protein
AnaeK_0890	COG0396	ATPase activity
AnaeK_0891	COG0719	Fe-S assembly protein
AnaeK_0892	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
AnaeK_0897	COG0793	Belongs to the peptidase S41A family
AnaeK_0899	COG0577	efflux transmembrane transporter activity
AnaeK_0899	COG1136	(ABC) transporter
AnaeK_0900	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AnaeK_0902	COG2197	response regulator
AnaeK_0908	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AnaeK_0909	COG0058	SHG alpha-glucan phosphorylase activity
AnaeK_0912	COG1704	LemA family
AnaeK_0917	COG1396	sequence-specific DNA binding
AnaeK_0918	COG0745	RESPONSE REGULATOR receiver
AnaeK_0919	COG0004	ammonium transporteR
AnaeK_0935	COG0668	transmembrane transport
AnaeK_0939	COG0745	RESPONSE REGULATOR receiver
AnaeK_0940	COG2205	protein histidine kinase activity
AnaeK_0942	COG0531	amino acid
AnaeK_0947	COG2322	membrane
AnaeK_0950	COG0109	protoheme IX farnesyltransferase activity
AnaeK_0953	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AnaeK_0956	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AnaeK_0958	COG0243	molybdopterin cofactor binding
AnaeK_0960	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AnaeK_0962	COG2132	Multicopper oxidase
AnaeK_0973	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AnaeK_0974	COG0830	nickel cation binding
AnaeK_0976	COG0831	urea catabolic process
AnaeK_0976	COG0832	Belongs to the urease beta subunit family
AnaeK_0977	COG0829	nickel cation binding
AnaeK_0979	COG4191	Histidine kinase
AnaeK_0983	COG2873	o-acetylhomoserine
AnaeK_0986	COG0432	Pfam Uncharacterised protein family UPF0047
AnaeK_0987	COG0003	Pfam Anion-transporting ATPase
AnaeK_0990	COG1192	Involved in chromosome partitioning
AnaeK_0992	COG2353	YceI-like domain
AnaeK_0993	COG3384	dioxygenase
AnaeK_0994	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
AnaeK_0997	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AnaeK_0998	COG0584	glycerophosphoryl diester phosphodiesterase
AnaeK_1000	COG1271	oxidase subunit
AnaeK_1001	COG1294	oxidase, subunit
AnaeK_1004	COG1331	Highly conserved protein containing a thioredoxin domain
AnaeK_1011	COG2814	Major facilitator Superfamily
AnaeK_1016	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AnaeK_1023	COG3285	dna ligase
AnaeK_1023	COG1793	dna ligase
AnaeK_1027	COG0427	acetyl-CoA hydrolase
AnaeK_1029	COG0745	RESPONSE REGULATOR receiver
AnaeK_1031	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AnaeK_1038	COG2814	Major facilitator Superfamily
AnaeK_1042	COG4783	chaperone-mediated protein folding
AnaeK_1045	COG1278	Cold shock
AnaeK_1048	COG1720	tRNA m6t6A37 methyltransferase activity
AnaeK_1056	COG3842	ATPase activity
AnaeK_1063	COG1129	ABC transporter
AnaeK_1064	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AnaeK_1075	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
AnaeK_1080	COG3239	Fatty acid desaturase
AnaeK_1087	COG1309	transcriptional regulator
AnaeK_1088	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AnaeK_1095	COG1335	isochorismatase
AnaeK_1096	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AnaeK_1099	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AnaeK_1101	COG1692	metallophosphoesterase
AnaeK_1106	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
AnaeK_1110	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AnaeK_1114	COG2204	response regulator
AnaeK_1120	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AnaeK_1122	COG0673	inositol 2-dehydrogenase activity
AnaeK_1126	COG1132	(ABC) transporter
AnaeK_1128	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AnaeK_1129	COG4221	oxidoreductase activity
AnaeK_1130	COG5000	phosphorelay sensor kinase activity
AnaeK_1135	COG1543	Belongs to the glycosyl hydrolase 57 family
AnaeK_1139	COG1136	(ABC) transporter
AnaeK_1140	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AnaeK_1145	COG3494	Protein of unknown function (DUF1009)
AnaeK_1147	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AnaeK_1148	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AnaeK_1149	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AnaeK_1151	COG0484	heat shock protein binding
AnaeK_1153	COG1570	exodeoxyribonuclease VII activity
AnaeK_1154	COG1722	exodeoxyribonuclease VII activity
AnaeK_1155	COG0745	RESPONSE REGULATOR receiver
AnaeK_1156	COG0142	geranyltranstransferase activity
AnaeK_1158	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
AnaeK_1165	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AnaeK_1169	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AnaeK_1171	COG5002	protein histidine kinase activity
AnaeK_1175	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AnaeK_1177	COG0546	phosphoglycolate phosphatase activity
AnaeK_1179	COG0745	RESPONSE REGULATOR receiver
AnaeK_1181	COG0750	zinc metalloprotease
AnaeK_1182	COG2078	PFAM AMMECR1 domain protein
AnaeK_1183	COG2816	NAD+ diphosphatase activity
AnaeK_1190	COG5002	protein histidine kinase activity
AnaeK_1192	COG1960	acyl-CoA dehydrogenase activity
AnaeK_1193	COG1324	tolerance protein
AnaeK_1195	COG0515	serine threonine protein kinase
AnaeK_1197	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AnaeK_1198	COG0616	signal peptide processing
AnaeK_1199	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
AnaeK_1200	COG1607	acyl-coa hydrolase
AnaeK_1204	COG1408	metallophosphoesterase
AnaeK_1206	COG0450	alkyl hydroperoxide reductase
AnaeK_1209	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
AnaeK_1214	COG1100	Small GTP-binding protein
AnaeK_1216	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AnaeK_1219	COG2226	methyltransferase
AnaeK_1220	COG0840	transmembrane signaling receptor activity
AnaeK_1221	COG1064	alcohol dehydrogenase
AnaeK_1224	COG0318	PFAM AMP-dependent synthetase and ligase
AnaeK_1225	COG3875	lactate racemase activity
AnaeK_1229	COG0243	molybdopterin cofactor binding
AnaeK_1230	COG3278	Belongs to the heme-copper respiratory oxidase family
AnaeK_1234	COG0348	domain, Protein
AnaeK_1237	COG2217	Heavy metal translocating P-type atpase
AnaeK_1239	COG1049	propionate catabolic process, 2-methylcitrate cycle
AnaeK_1245	COG0114	fumarate hydratase activity
AnaeK_1249	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AnaeK_1254	COG1355	regulation of microtubule-based process
AnaeK_1258	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AnaeK_1260	COG0443	Heat shock 70 kDa protein
AnaeK_1261	COG0484	heat shock protein binding
AnaeK_1263	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AnaeK_1264	COG0010	Belongs to the arginase family
AnaeK_1265	COG1959	2 iron, 2 sulfur cluster binding
AnaeK_1266	COG0613	PHP domain protein
AnaeK_1267	COG1007	ATP synthesis coupled electron transport
AnaeK_1270	COG0713	ATP synthesis coupled electron transport
AnaeK_1272	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AnaeK_1273	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AnaeK_1275	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AnaeK_1277	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AnaeK_1280	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AnaeK_1283	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AnaeK_1284	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AnaeK_1287	COG2223	nitrite transmembrane transporter activity
AnaeK_1288	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
AnaeK_1288	COG1796	DNA polymerase
AnaeK_1290	COG0521	Mo-molybdopterin cofactor biosynthetic process
AnaeK_1294	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AnaeK_1303	COG0586	Pfam SNARE associated Golgi protein
AnaeK_1304	COG2385	sporulation resulting in formation of a cellular spore
AnaeK_1307	COG0343	queuine tRNA-ribosyltransferase activity
AnaeK_1308	COG1862	Preprotein translocase
AnaeK_1309	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AnaeK_1310	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AnaeK_1313	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AnaeK_1313	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
AnaeK_1314	COG0604	alcohol dehydrogenase
AnaeK_1317	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
AnaeK_1322	COG1597	lipid kinase activity
AnaeK_1328	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AnaeK_1329	COG0612	Peptidase, M16
AnaeK_1333	COG0783	Belongs to the Dps family
AnaeK_1337	COG0352	thiamine-phosphate diphosphorylase activity
AnaeK_1341	COG1074	ATP-dependent DNA helicase activity
AnaeK_1344	COG1830	Aldolase
AnaeK_1352	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AnaeK_1354	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AnaeK_1357	COG0768	penicillin binding
AnaeK_1358	COG0772	Belongs to the SEDS family
AnaeK_1359	COG3118	belongs to the thioredoxin family
AnaeK_1362	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AnaeK_1363	COG0181	hydroxymethylbilane synthase activity
AnaeK_1366	COG0585	pseudouridine synthase activity
AnaeK_1367	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AnaeK_1370	COG0587	DNA-directed DNA polymerase activity
AnaeK_1378	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
AnaeK_1379	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AnaeK_1380	COG0446	pyridine nucleotide-disulphide oxidoreductase
AnaeK_1380	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AnaeK_1383	COG0312	modulator of DNA gyrase
AnaeK_1401	COG1216	Glycosyl transferase, family 2
AnaeK_1404	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AnaeK_1405	COG0009	L-threonylcarbamoyladenylate synthase
AnaeK_1407	COG0113	porphobilinogen synthase activity
AnaeK_1410	COG1181	Belongs to the D-alanine--D-alanine ligase family
AnaeK_1417	COG0784	Response regulator, receiver
AnaeK_1417	COG2205	protein histidine kinase activity
AnaeK_1428	COG0745	RESPONSE REGULATOR receiver
AnaeK_1431	COG0557	exoribonuclease II activity
AnaeK_1433	COG0730	response to heat
AnaeK_1434	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AnaeK_1436	COG0411	ABC transporter
AnaeK_1438	COG0559	Belongs to the binding-protein-dependent transport system permease family
AnaeK_1441	COG1193	negative regulation of DNA recombination
AnaeK_1448	COG1595	DNA-templated transcription, initiation
AnaeK_1452	COG3876	Protein conserved in bacteria
AnaeK_1456	COG0542	response to heat
AnaeK_1461	COG4263	nitrous-oxide reductase activity
AnaeK_1467	COG1752	Esterase of the alpha-beta hydrolase superfamily
AnaeK_1470	COG0459	protein refolding
AnaeK_1471	COG3706	GGDEF domain
AnaeK_1474	COG0525	valine-tRNA ligase activity
AnaeK_1476	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AnaeK_1476	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AnaeK_1486	COG1595	DNA-templated transcription, initiation
AnaeK_1488	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AnaeK_1494	COG1573	uracil-dna glycosylase
AnaeK_1496	COG0330	HflC and HflK could
AnaeK_1499	COG0183	Belongs to the thiolase family
AnaeK_1500	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AnaeK_1504	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AnaeK_1512	COG0501	Belongs to the peptidase M48B family
AnaeK_1516	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AnaeK_1518	COG0586	Pfam SNARE associated Golgi protein
AnaeK_1519	COG0443	Heat shock 70 kDa protein
AnaeK_1520	COG0517	IMP dehydrogenase activity
AnaeK_1520	COG0516	GMP reductase activity
AnaeK_1521	COG0519	Catalyzes the synthesis of GMP from XMP
AnaeK_1521	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AnaeK_1525	COG4566	intracellular signal transduction
AnaeK_1525	COG0745	RESPONSE REGULATOR receiver
AnaeK_1527	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AnaeK_1529	COG3746	phosphate-selective porin O and P
AnaeK_1531	COG1121	(ABC) transporter
AnaeK_1535	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AnaeK_1549	COG2801	Transposase and inactivated derivatives
AnaeK_1551	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AnaeK_1552	COG0569	domain protein
AnaeK_1552	COG2985	domain, Protein
AnaeK_1558	COG0436	Aminotransferase
AnaeK_1560	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AnaeK_1562	COG1028	Short-chain dehydrogenase reductase Sdr
AnaeK_1562	COG3347	Dehydrogenase
AnaeK_1564	COG0509	glycine decarboxylation via glycine cleavage system
AnaeK_1565	COG0300	oxidoreductase activity
AnaeK_1566	COG5322	oxidoreductase activity
AnaeK_1566	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AnaeK_1567	COG0243	molybdopterin cofactor binding
AnaeK_1580	COG2814	Major facilitator Superfamily
AnaeK_1583	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AnaeK_1589	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AnaeK_1595	COG2010	Cytochrome c
AnaeK_1596	COG0737	Belongs to the 5'-nucleotidase family
AnaeK_1601	COG1845	cytochrome c oxidase, subunit III
AnaeK_1601	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
AnaeK_1605	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AnaeK_1614	COG4651	solute:proton antiporter activity
AnaeK_1614	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AnaeK_1615	COG0443	Heat shock 70 kDa protein
AnaeK_1620	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
AnaeK_1620	COG0392	lysyltransferase activity
AnaeK_1623	COG1595	DNA-templated transcription, initiation
AnaeK_1630	COG2259	Doxx family
AnaeK_1634	COG4191	Histidine kinase
AnaeK_1635	COG2204	response regulator
AnaeK_1638	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AnaeK_1647	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AnaeK_1649	COG0039	L-malate dehydrogenase activity
AnaeK_1654	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AnaeK_1654	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AnaeK_1656	COG0004	ammonium transporteR
AnaeK_1661	COG2814	Major facilitator Superfamily
AnaeK_1662	COG0583	DNA-binding transcription factor activity
AnaeK_1664	COG2205	protein histidine kinase activity
AnaeK_1665	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AnaeK_1667	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AnaeK_1669	COG1741	Belongs to the pirin family
AnaeK_1674	COG0583	DNA-binding transcription factor activity
AnaeK_1675	COG3118	belongs to the thioredoxin family
AnaeK_1680	COG0583	DNA-binding transcription factor activity
AnaeK_1683	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AnaeK_1684	COG1592	Rubrerythrin
AnaeK_1685	COG2205	protein histidine kinase activity
AnaeK_1691	COG0840	transmembrane signaling receptor activity
AnaeK_1692	COG0835	chemotaxis
AnaeK_1696	COG0410	ABC transporter
AnaeK_1699	COG0683	leucine binding
AnaeK_1700	COG0730	response to heat
AnaeK_1702	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AnaeK_1704	COG2223	nitrite transmembrane transporter activity
AnaeK_1707	COG1140	nitrate reductase beta subunit
AnaeK_1708	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
AnaeK_1710	COG4191	Histidine kinase
AnaeK_1719	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AnaeK_1721	COG0488	(ABC) transporter
AnaeK_1724	COG2818	Glycosylase
AnaeK_1725	COG1252	NADH dehydrogenase
AnaeK_1726	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AnaeK_1728	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AnaeK_1728	COG4191	Histidine kinase
AnaeK_1735	COG0785	Cytochrome C biogenesis protein
AnaeK_1738	COG2814	Major facilitator Superfamily
AnaeK_1739	COG0252	asparaginase activity
AnaeK_1742	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
AnaeK_1744	COG0508	dehydrogenase complex catalyzes the overall conversion of
AnaeK_1745	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
AnaeK_1754	COG1595	DNA-templated transcription, initiation
AnaeK_1755	COG0667	Aldo Keto reductase
AnaeK_1762	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AnaeK_1764	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AnaeK_1767	COG0686	Belongs to the AlaDH PNT family
AnaeK_1768	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AnaeK_1769	COG2226	methyltransferase
AnaeK_1770	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AnaeK_1773	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AnaeK_1774	COG4191	Histidine kinase
AnaeK_1774	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AnaeK_1775	COG2204	response regulator
AnaeK_1782	COG1053	succinate dehydrogenase
AnaeK_1784	COG0156	8-amino-7-oxononanoate synthase activity
AnaeK_1786	COG1201	RNA secondary structure unwinding
AnaeK_1787	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AnaeK_1788	COG2205	protein histidine kinase activity
AnaeK_1788	COG0784	Response regulator, receiver
AnaeK_1788	COG5002	protein histidine kinase activity
AnaeK_1790	COG0437	4 iron, 4 sulfur cluster binding
AnaeK_1790	COG3064	Membrane
AnaeK_1791	COG3058	Necessary for formate dehydrogenase activity
AnaeK_1793	COG0626	cystathionine gamma-synthase activity
AnaeK_1798	COG2195	Cleaves the N-terminal amino acid of tripeptides
AnaeK_1801	COG0667	Aldo Keto reductase
AnaeK_1806	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AnaeK_1807	COG0473	3-isopropylmalate dehydrogenase activity
AnaeK_1808	COG2755	lipolytic protein G-D-S-L family
AnaeK_1808	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
AnaeK_1809	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
AnaeK_1809	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
AnaeK_1810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
AnaeK_1816	COG0488	(ABC) transporter
AnaeK_1819	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AnaeK_1821	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AnaeK_1823	COG1164	Oligoendopeptidase f
AnaeK_1827	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AnaeK_1830	COG0351	phosphomethylpyrimidine kinase
AnaeK_1832	COG2095	MarC family integral membrane protein
AnaeK_1835	COG1136	(ABC) transporter
AnaeK_1836	COG0577	efflux transmembrane transporter activity
AnaeK_1836	COG1136	(ABC) transporter
AnaeK_1839	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
AnaeK_1841	COG2373	Large extracellular alpha-helical protein
AnaeK_1842	COG4953	penicillin-binding protein 1C
AnaeK_1850	COG0656	L-ascorbic acid biosynthetic process
AnaeK_1856	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AnaeK_1860	COG0501	Belongs to the peptidase M48B family
AnaeK_1861	COG0583	DNA-binding transcription factor activity
AnaeK_1864	COG0408	coproporphyrinogen oxidase activity
AnaeK_1866	COG0788	formyltetrahydrofolate deformylase activity
AnaeK_1869	COG2204	response regulator
AnaeK_1871	COG3064	Membrane
AnaeK_1871	COG0437	4 iron, 4 sulfur cluster binding
AnaeK_1872	COG5557	Pfam Polysulphide reductase, NrfD
AnaeK_1873	COG0509	glycine decarboxylation via glycine cleavage system
AnaeK_1880	COG4585	Histidine kinase
AnaeK_1881	COG2197	response regulator
AnaeK_1884	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AnaeK_1885	COG4191	Histidine kinase
AnaeK_1886	COG2204	response regulator
AnaeK_1887	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AnaeK_1894	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AnaeK_1897	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AnaeK_1906	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AnaeK_1907	COG0072	phenylalanine-tRNA ligase activity
AnaeK_1911	COG2146	nitrite reductase [NAD(P)H] activity
AnaeK_1912	COG0720	synthase
AnaeK_1913	COG0302	gtp cyclohydrolase
AnaeK_1914	COG1028	Short-chain dehydrogenase reductase Sdr
AnaeK_1915	COG0277	FAD linked oxidase domain protein
AnaeK_1916	COG0674	pyruvate-flavodoxin oxidoreductase activity
AnaeK_1916	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AnaeK_1917	COG1013	pyruvate-flavodoxin oxidoreductase activity
AnaeK_1919	COG0674	pyruvate-flavodoxin oxidoreductase activity
AnaeK_1919	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AnaeK_1920	COG1013	pyruvate-flavodoxin oxidoreductase activity
AnaeK_1924	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AnaeK_1926	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AnaeK_1927	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AnaeK_1931	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AnaeK_1932	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AnaeK_1941	COG0255	Belongs to the universal ribosomal protein uL29 family
AnaeK_1950	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AnaeK_1953	COG0201	protein transport
AnaeK_1957	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AnaeK_1958	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AnaeK_1964	COG1837	Belongs to the UPF0109 family
AnaeK_1965	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AnaeK_1969	COG0792	nuclease activity
AnaeK_1972	COG3852	Histidine kinase
AnaeK_1973	COG0741	lytic transglycosylase activity
AnaeK_1975	COG2894	cell division
AnaeK_1978	COG0564	pseudouridine synthase activity
AnaeK_1981	COG2226	methyltransferase
AnaeK_1983	COG1166	arginine decarboxylase activity
AnaeK_1987	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AnaeK_1995	COG0564	pseudouridine synthase activity
AnaeK_1997	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AnaeK_1998	COG1127	ABC transporter
AnaeK_2000	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AnaeK_2002	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AnaeK_2009	COG1024	Enoyl-CoA hydratase
AnaeK_2010	COG2205	protein histidine kinase activity
AnaeK_2028	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AnaeK_2030	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AnaeK_2032	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AnaeK_2033	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
AnaeK_2034	COG0022	dehydrogenase e1 component
AnaeK_2037	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AnaeK_2038	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AnaeK_2041	COG1297	OPT oligopeptide transporter protein
AnaeK_2045	COG0527	aspartate kinase activity
AnaeK_2050	COG1574	metal-dependent hydrolase with the TIM-barrel fold
AnaeK_2052	COG0210	DNA helicase
AnaeK_2053	COG0443	Heat shock 70 kDa protein
AnaeK_2058	COG2205	protein histidine kinase activity
AnaeK_2064	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AnaeK_2068	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AnaeK_2069	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AnaeK_2074	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AnaeK_2078	COG2197	response regulator
AnaeK_2081	COG4191	Histidine kinase
AnaeK_2081	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AnaeK_2082	COG2204	response regulator
AnaeK_2083	COG1027	Aspartate ammonia-lyase
AnaeK_2084	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
AnaeK_2085	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
AnaeK_2097	COG0464	growth
AnaeK_2107	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AnaeK_2108	COG4208	sulfate ABC transporter
AnaeK_2110	COG0175	sulfate reduction
AnaeK_2111	COG2895	sulfate adenylyltransferase (ATP) activity
AnaeK_2112	COG0175	sulfate reduction
AnaeK_2114	COG0742	ribosomal rna small subunit methyltransferase
AnaeK_2118	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AnaeK_2120	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AnaeK_2123	COG0436	Aminotransferase
AnaeK_2126	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AnaeK_2127	COG1058	Belongs to the CinA family
AnaeK_2127	COG1546	Belongs to the CinA family
AnaeK_2137	COG2204	response regulator
AnaeK_2139	COG0515	serine threonine protein kinase
AnaeK_2139	COG2815	serine threonine protein kinase
AnaeK_2141	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AnaeK_2152	COG1215	transferase activity, transferring glycosyl groups
AnaeK_2160	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AnaeK_2165	COG0189	ligase activity
AnaeK_2168	COG0009	L-threonylcarbamoyladenylate synthase
AnaeK_2169	COG4974	Belongs to the 'phage' integrase family
AnaeK_2170	COG1994	Peptidase M50
AnaeK_2171	COG0180	Tryptophanyl-tRNA synthetase
AnaeK_2172	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AnaeK_2173	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AnaeK_2174	COG1187	pseudouridine synthase activity
AnaeK_2178	COG1595	DNA-templated transcription, initiation
AnaeK_2180	COG0430	RNA-3'-phosphate cyclase activity
AnaeK_2181	COG0598	Magnesium transport protein CorA
AnaeK_2183	COG0489	protein tyrosine kinase activity
AnaeK_2189	COG2205	protein histidine kinase activity
AnaeK_2190	COG1250	3-hydroxyacyl-CoA dehydrogenase
AnaeK_2191	COG1024	Enoyl-CoA hydratase
AnaeK_2192	COG1960	acyl-CoA dehydrogenase activity
AnaeK_2193	COG1960	acyl-CoA dehydrogenase activity
AnaeK_2194	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AnaeK_2194	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AnaeK_2199	COG3005	denitrification pathway
AnaeK_2201	COG0494	nUDIX hydrolase
AnaeK_2204	COG1160	GTP binding
AnaeK_2205	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AnaeK_2208	COG0571	ribonuclease III activity
AnaeK_2211	COG1960	acyl-CoA dehydrogenase activity
AnaeK_2212	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AnaeK_2213	COG1024	Enoyl-CoA hydratase
AnaeK_2220	COG1494	fructose-1,6-bisphosphatase
AnaeK_2229	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AnaeK_2230	COG1253	flavin adenine dinucleotide binding
AnaeK_2232	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AnaeK_2234	COG0039	L-malate dehydrogenase activity
AnaeK_2235	COG0538	isocitrate dehydrogenase activity
AnaeK_2237	COG4191	Histidine kinase
AnaeK_2240	COG0505	Belongs to the CarA family
AnaeK_2243	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
AnaeK_2245	COG0681	Belongs to the peptidase S26 family
AnaeK_2247	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AnaeK_2250	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AnaeK_2254	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AnaeK_2255	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
AnaeK_2256	COG5002	protein histidine kinase activity
AnaeK_2265	COG0745	RESPONSE REGULATOR receiver
AnaeK_2279	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AnaeK_2280	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AnaeK_2282	COG0189	ligase activity
AnaeK_2283	COG0443	Heat shock 70 kDa protein
AnaeK_2285	COG2921	Belongs to the UPF0250 family
AnaeK_2286	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AnaeK_2287	COG0745	RESPONSE REGULATOR receiver
AnaeK_2287	COG3706	GGDEF domain
AnaeK_2291	COG1309	transcriptional regulator
AnaeK_2296	COG1730	sister chromatid segregation
AnaeK_2309	COG3706	GGDEF domain
AnaeK_2309	COG0745	RESPONSE REGULATOR receiver
AnaeK_2310	COG2204	response regulator
AnaeK_2311	COG4191	Histidine kinase
AnaeK_2312	COG2843	Capsule synthesis protein
AnaeK_2317	COG0443	Heat shock 70 kDa protein
AnaeK_2319	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AnaeK_2322	COG0101	tRNA pseudouridine synthase activity
AnaeK_2326	COG0529	Catalyzes the synthesis of activated sulfate
AnaeK_2329	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AnaeK_2331	COG0443	Heat shock 70 kDa protein
AnaeK_2335	COG0149	triose-phosphate isomerase activity
AnaeK_2337	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AnaeK_2339	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
AnaeK_2346	COG0616	signal peptide processing
AnaeK_2347	COG0539	negative regulation of cytoplasmic translation
AnaeK_2347	COG2183	response to ionizing radiation
AnaeK_2351	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AnaeK_2353	COG0825	malonyl-CoA metabolic process
AnaeK_2359	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
AnaeK_2364	COG0802	atpase or kinase
AnaeK_2365	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AnaeK_2365	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AnaeK_2367	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AnaeK_2368	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AnaeK_2370	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
AnaeK_2371	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AnaeK_2372	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AnaeK_2373	COG0037	tRNA processing
AnaeK_2373	COG0590	tRNA wobble adenosine to inosine editing
AnaeK_2376	COG0004	ammonium transporteR
AnaeK_2379	COG0776	regulation of translation
AnaeK_2380	COG3246	L-lysine catabolic process to acetate
AnaeK_2381	COG1607	acyl-coa hydrolase
AnaeK_2382	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AnaeK_2384	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
AnaeK_2385	COG0482	sulfurtransferase activity
AnaeK_2386	COG2198	Histidine kinase
AnaeK_2386	COG0784	Response regulator, receiver
AnaeK_2386	COG2205	protein histidine kinase activity
AnaeK_2387	COG0617	tRNA 3'-terminal CCA addition
AnaeK_2390	COG2204	response regulator
AnaeK_2395	COG5002	protein histidine kinase activity
AnaeK_2396	COG2205	protein histidine kinase activity
AnaeK_2397	COG0024	Methionine aminopeptidase
AnaeK_2401	COG0840	transmembrane signaling receptor activity
AnaeK_2406	COG2353	YceI-like domain
AnaeK_2407	COG0259	pyridoxamine-phosphate oxidase activity
AnaeK_2411	COG4191	Histidine kinase
AnaeK_2412	COG2204	response regulator
AnaeK_2413	COG0589	response to stress
AnaeK_2418	COG3387	PFAM Glycoside hydrolase 15-related
AnaeK_2419	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
AnaeK_2420	COG0363	glucosamine-6-phosphate deaminase activity
AnaeK_2421	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
AnaeK_2422	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
AnaeK_2423	COG1022	Amp-dependent synthetase and ligase
AnaeK_2428	COG2515	1-aminocyclopropane-1-carboxylate deaminase
AnaeK_2432	COG0343	queuine tRNA-ribosyltransferase activity
AnaeK_2433	COG0429	hydrolase of the alpha beta-hydrolase fold
AnaeK_2437	COG0437	4 iron, 4 sulfur cluster binding
AnaeK_2439	COG0038	chloride channel
AnaeK_2449	COG4301	Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine
AnaeK_2450	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AnaeK_2451	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
AnaeK_2456	COG3604	Transcriptional regulator
AnaeK_2458	COG2204	response regulator
AnaeK_2461	COG1558	bacterial-type flagellum-dependent cell motility
AnaeK_2462	COG1677	Flagellar hook-basal body complex protein FliE
AnaeK_2464	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
AnaeK_2472	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
AnaeK_2473	COG1360	Flagellar Motor Protein
AnaeK_2474	COG2201	protein-glutamate methylesterase activity
AnaeK_2475	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AnaeK_2476	COG0835	chemotaxis
AnaeK_2478	COG2198	Histidine kinase
AnaeK_2478	COG0643	Histidine kinase
AnaeK_2479	COG0745	RESPONSE REGULATOR receiver
AnaeK_2482	COG0835	chemotaxis
AnaeK_2483	COG0840	transmembrane signaling receptor activity
AnaeK_2484	COG2201	protein-glutamate methylesterase activity
AnaeK_2485	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AnaeK_2490	COG1639	'signal transduction protein
AnaeK_2495	COG1338	Plays a role in the flagellum-specific transport system
AnaeK_2496	COG1987	bacterial-type flagellum assembly
AnaeK_2497	COG1684	flagellar biosynthetic protein fliR
AnaeK_2498	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AnaeK_2499	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
AnaeK_2501	COG0455	bacterial-type flagellum organization
AnaeK_2505	COG4786	Flagellar basal body rod
AnaeK_2506	COG4786	Flagellar basal body rod
AnaeK_2510	COG0739	heme binding
AnaeK_2515	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AnaeK_2516	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
AnaeK_2519	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
AnaeK_2521	COG0457	Tetratricopeptide repeat
AnaeK_2521	COG0463	Glycosyl transferase, family 2
AnaeK_2524	COG1763	Mo-molybdopterin cofactor biosynthetic process
AnaeK_2525	COG0303	'Molybdopterin
AnaeK_2527	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AnaeK_2529	COG2239	Acts as a magnesium transporter
AnaeK_2530	COG2205	protein histidine kinase activity
AnaeK_2531	COG0745	RESPONSE REGULATOR receiver
AnaeK_2531	COG4566	intracellular signal transduction
AnaeK_2532	COG4191	Histidine kinase
AnaeK_2533	COG2204	response regulator
AnaeK_2542	COG1335	isochorismatase
AnaeK_2543	COG3481	metal-dependent phosphohydrolase, HD sub domain
AnaeK_2545	COG0084	hydrolase, TatD family'
AnaeK_2546	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AnaeK_2546	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AnaeK_2549	COG3599	regulation of cell shape
AnaeK_2562	COG0602	queuosine metabolic process
AnaeK_2563	COG0741	lytic transglycosylase activity
AnaeK_2571	COG2937	Belongs to the GPAT DAPAT family
AnaeK_2573	COG0483	inositol monophosphate 1-phosphatase activity
AnaeK_2575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AnaeK_2576	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AnaeK_2580	COG1045	serine acetyltransferase
AnaeK_2583	COG3258	Cytochrome c
AnaeK_2586	COG0556	nucleotide-excision repair
AnaeK_2588	COG1278	Cold shock
AnaeK_2591	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AnaeK_2591	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AnaeK_2593	COG0658	competence protein
AnaeK_2593	COG2333	competence protein COMEC
AnaeK_2601	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AnaeK_2603	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AnaeK_2606	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AnaeK_2607	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AnaeK_2609	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AnaeK_2612	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
AnaeK_2615	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
AnaeK_2618	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AnaeK_2620	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AnaeK_2623	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AnaeK_2627	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AnaeK_2629	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AnaeK_2630	COG1278	Cold shock
AnaeK_2634	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AnaeK_2635	COG2766	serine protein kinase
AnaeK_2636	COG2718	Belongs to the UPF0229 family
AnaeK_2637	COG2719	SpoVR family
AnaeK_2641	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
AnaeK_2646	COG1047	Peptidyl-prolyl cis-trans
AnaeK_2648	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AnaeK_2650	COG3411	Ferredoxin
AnaeK_2654	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
AnaeK_2661	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AnaeK_2664	COG5002	protein histidine kinase activity
AnaeK_2673	COG1269	ATP hydrolysis coupled proton transport
AnaeK_2679	COG2201	protein-glutamate methylesterase activity
AnaeK_2680	COG2205	protein histidine kinase activity
AnaeK_2682	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AnaeK_2686	COG1309	transcriptional regulator
AnaeK_2690	COG1573	uracil-dna glycosylase
AnaeK_2691	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AnaeK_2692	COG0194	GDP metabolic process
AnaeK_2693	COG1561	YicC-like family, N-terminal region
AnaeK_2694	COG2835	tetraacyldisaccharide 4'-kinase activity
AnaeK_2696	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AnaeK_2696	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AnaeK_2698	COG1560	Kdo2-lipid A biosynthetic process
AnaeK_2700	COG0859	PFAM glycosyl transferase family 9
AnaeK_2701	COG1519	Transferase
AnaeK_2703	COG1132	(ABC) transporter
AnaeK_2704	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AnaeK_2705	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AnaeK_2708	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AnaeK_2709	COG2095	MarC family integral membrane protein
AnaeK_2710	COG1216	Glycosyl transferase, family 2
AnaeK_2717	COG0437	4 iron, 4 sulfur cluster binding
AnaeK_2718	COG0243	molybdopterin cofactor binding
AnaeK_2720	COG5002	protein histidine kinase activity
AnaeK_2721	COG0745	RESPONSE REGULATOR receiver
AnaeK_2723	COG1053	succinate dehydrogenase
AnaeK_2725	COG0438	transferase activity, transferring glycosyl groups
AnaeK_2732	COG0391	Required for morphogenesis under gluconeogenic growth conditions
AnaeK_2733	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AnaeK_2735	COG0489	protein tyrosine kinase activity
AnaeK_2740	COG2204	response regulator
AnaeK_2744	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AnaeK_2747	COG0577	efflux transmembrane transporter activity
AnaeK_2747	COG1136	(ABC) transporter
AnaeK_2758	COG0492	ferredoxin-NADP+ reductase activity
AnaeK_2761	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
AnaeK_2765	COG2169	Transcriptional regulator
AnaeK_2769	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AnaeK_2770	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AnaeK_2777	COG0237	dephospho-CoA kinase activity
AnaeK_2782	COG0443	Heat shock 70 kDa protein
AnaeK_2784	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AnaeK_2785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AnaeK_2786	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AnaeK_2792	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
AnaeK_2794	COG1652	LysM domain
AnaeK_2797	COG3706	GGDEF domain
AnaeK_2797	COG2203	Gaf domain
AnaeK_2797	COG5001	Diguanylate cyclase
AnaeK_2797	COG4251	negative regulation of phosphorylation
AnaeK_2798	COG0745	RESPONSE REGULATOR receiver
AnaeK_2798	COG1196	nuclear chromosome segregation
AnaeK_2800	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AnaeK_2803	COG0438	transferase activity, transferring glycosyl groups
AnaeK_2805	COG4932	domain protein
AnaeK_2805	COG5492	domain, Protein
AnaeK_2809	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AnaeK_2812	COG1480	7TM receptor with intracellular HD hydrolase
AnaeK_2814	COG0457	Tetratricopeptide repeat
AnaeK_2816	COG3956	TIGRFAM MazG family protein
AnaeK_2819	COG0495	leucyl-tRNA aminoacylation
AnaeK_2820	COG0017	Asparaginyl-tRNA synthetase
AnaeK_2822	COG2201	protein-glutamate methylesterase activity
AnaeK_2823	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AnaeK_2825	COG0835	chemotaxis
AnaeK_2827	COG3267	Type II secretory pathway component ExeA
AnaeK_2827	COG3409	Peptidoglycan-binding domain 1 protein
AnaeK_2828	COG0643	Histidine kinase
AnaeK_2828	COG2198	Histidine kinase
AnaeK_2832	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AnaeK_2832	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AnaeK_2834	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AnaeK_2834	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AnaeK_2837	COG0698	ribose 5-phosphate isomerase
AnaeK_2839	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AnaeK_2841	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
AnaeK_2842	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AnaeK_2844	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AnaeK_2851	COG2827	Endonuclease containing a URI domain
AnaeK_2857	COG0438	transferase activity, transferring glycosyl groups
AnaeK_2858	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AnaeK_2861	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
AnaeK_2864	COG0367	asparagine synthase
AnaeK_2865	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
AnaeK_2866	COG0318	PFAM AMP-dependent synthetase and ligase
AnaeK_2879	COG0438	transferase activity, transferring glycosyl groups
AnaeK_2880	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AnaeK_2884	COG0438	transferase activity, transferring glycosyl groups
AnaeK_2885	COG0493	'glutamate synthase
AnaeK_2885	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AnaeK_2891	COG0515	serine threonine protein kinase
AnaeK_2891	COG2815	serine threonine protein kinase
AnaeK_2895	COG3186	Phenylalanine-4-hydroxylase
AnaeK_2896	COG0488	(ABC) transporter
AnaeK_2898	COG0745	RESPONSE REGULATOR receiver
AnaeK_2900	COG0784	Response regulator, receiver
AnaeK_2900	COG2198	Histidine kinase
AnaeK_2900	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AnaeK_2900	COG2205	protein histidine kinase activity
AnaeK_2906	COG1028	Short-chain dehydrogenase reductase Sdr
AnaeK_2914	COG2894	cell division
AnaeK_2915	COG4964	Belongs to the GSP D family
AnaeK_2932	COG0604	alcohol dehydrogenase
AnaeK_2938	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AnaeK_2940	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AnaeK_2948	COG1301	dicarboxylic acid transport
AnaeK_2951	COG0247	lactate metabolic process
AnaeK_2952	COG0277	FAD linked oxidase domain protein
AnaeK_2953	COG0277	FAD linked oxidase domain protein
AnaeK_2967	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AnaeK_2971	COG2226	methyltransferase
AnaeK_2977	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AnaeK_2980	COG0406	alpha-ribazole phosphatase activity
AnaeK_2983	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AnaeK_2984	COG0702	epimerase
AnaeK_2987	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
AnaeK_2989	COG0318	PFAM AMP-dependent synthetase and ligase
AnaeK_2990	COG0671	phosphoesterase, PA-phosphatase related
AnaeK_2997	COG1376	ErfK ybiS ycfS ynhG family protein
AnaeK_2997	COG1388	LysM domain
AnaeK_3000	COG0745	RESPONSE REGULATOR receiver
AnaeK_3001	COG2205	protein histidine kinase activity
AnaeK_3010	COG1215	transferase activity, transferring glycosyl groups
AnaeK_3011	COG0726	polysaccharide deacetylase
AnaeK_3011	COG1649	PFAM Uncharacterised BCR, COG1649
AnaeK_3013	COG4968	Prepilin-type N-terminal cleavage methylation domain
AnaeK_3019	COG1053	succinate dehydrogenase
AnaeK_3023	COG1404	Belongs to the peptidase S8 family
AnaeK_3023	COG3087	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AnaeK_3025	COG2267	carboxylic ester hydrolase activity
AnaeK_3029	COG2205	protein histidine kinase activity
AnaeK_3029	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AnaeK_3030	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AnaeK_3041	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AnaeK_3042	COG0513	Belongs to the DEAD box helicase family
AnaeK_3043	COG2202	Pas domain
AnaeK_3043	COG2205	protein histidine kinase activity
AnaeK_3046	COG2271	Major facilitator Superfamily
AnaeK_3048	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AnaeK_3051	COG0484	heat shock protein binding
AnaeK_3058	COG0577	efflux transmembrane transporter activity
AnaeK_3058	COG1136	(ABC) transporter
AnaeK_3059	COG4591	ABC-type transport system involved in lipoprotein release permease component
AnaeK_3059	COG1136	(ABC) transporter
AnaeK_3060	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AnaeK_3061	COG3275	phosphorelay sensor kinase activity
AnaeK_3062	COG3279	Response regulator of the LytR AlgR family
AnaeK_3064	COG1620	l-lactate permease
AnaeK_3066	COG1139	Iron-sulfur cluster binding protein
AnaeK_3069	COG2226	methyltransferase
AnaeK_3080	COG2264	protein methyltransferase activity
AnaeK_3086	COG2860	membrane
AnaeK_3092	COG4106	trans-aconitate 2-methyltransferase activity
AnaeK_3093	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AnaeK_3094	COG0745	RESPONSE REGULATOR receiver
AnaeK_3096	COG1396	sequence-specific DNA binding
AnaeK_3096	COG3800	Transcriptional regulator
AnaeK_3097	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AnaeK_3101	COG0366	Alpha amylase catalytic
AnaeK_3104	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AnaeK_3105	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AnaeK_3106	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
AnaeK_3108	COG0318	PFAM AMP-dependent synthetase and ligase
AnaeK_3111	COG1013	pyruvate-flavodoxin oxidoreductase activity
AnaeK_3112	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AnaeK_3112	COG0674	pyruvate-flavodoxin oxidoreductase activity
AnaeK_3114	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AnaeK_3116	COG2703	oxygen carrier activity
AnaeK_3117	COG0277	FAD linked oxidase domain protein
AnaeK_3118	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
AnaeK_3121	COG1960	acyl-CoA dehydrogenase activity
AnaeK_3124	COG0702	epimerase
AnaeK_3126	COG3272	Protein of unknown function (DUF1722)
AnaeK_3128	COG1295	ribonuclease BN
AnaeK_3130	COG0443	Heat shock 70 kDa protein
AnaeK_3131	COG0443	Heat shock 70 kDa protein
AnaeK_3134	COG0667	Aldo Keto reductase
AnaeK_3135	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AnaeK_3138	COG0667	Aldo Keto reductase
AnaeK_3139	COG0693	protein deglycase activity
AnaeK_3142	COG0513	Belongs to the DEAD box helicase family
AnaeK_3147	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AnaeK_3148	COG1216	Glycosyl transferase, family 2
AnaeK_3149	COG1216	Glycosyl transferase, family 2
AnaeK_3156	COG0456	acetyltransferase
AnaeK_3157	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AnaeK_3160	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AnaeK_3183	COG0840	transmembrane signaling receptor activity
AnaeK_3184	COG0137	argininosuccinate synthase activity
AnaeK_3191	COG2204	response regulator
AnaeK_3195	COG0702	epimerase
AnaeK_3200	COG2267	carboxylic ester hydrolase activity
AnaeK_3202	COG0535	radical SAM domain protein
AnaeK_3204	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AnaeK_3205	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AnaeK_3206	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
AnaeK_3214	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
AnaeK_3214	COG3608	succinylglutamate desuccinylase aspartoacylase
AnaeK_3217	COG0339	signal peptide processing
AnaeK_3218	COG3852	Histidine kinase
AnaeK_3220	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AnaeK_3221	COG1131	(ABC) transporter
AnaeK_3222	COG1131	(ABC) transporter
AnaeK_3223	COG0842	Transport permease protein
AnaeK_3224	COG0842	Transport permease protein
AnaeK_3225	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
AnaeK_3226	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AnaeK_3226	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AnaeK_3236	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
AnaeK_3237	COG1595	DNA-templated transcription, initiation
AnaeK_3240	COG1162	GTPase activity
AnaeK_3241	COG0784	Response regulator, receiver
AnaeK_3241	COG2205	protein histidine kinase activity
AnaeK_3244	COG1309	transcriptional regulator
AnaeK_3245	COG1028	Short-chain dehydrogenase reductase Sdr
AnaeK_3250	COG3852	Histidine kinase
AnaeK_3252	COG0626	cystathionine gamma-synthase activity
AnaeK_3253	COG1136	(ABC) transporter
AnaeK_3259	COG0723	plastoquinol--plastocyanin reductase activity
AnaeK_3265	COG2855	membrane
AnaeK_3268	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AnaeK_3278	COG0840	transmembrane signaling receptor activity
AnaeK_3283	COG1064	alcohol dehydrogenase
AnaeK_3286	COG1131	(ABC) transporter
AnaeK_3287	COG0025	NhaP-type Na H and K H
AnaeK_3290	COG2860	membrane
AnaeK_3292	COG1278	Cold shock
AnaeK_3293	COG0596	Alpha beta hydrolase
AnaeK_3293	COG0508	dehydrogenase complex catalyzes the overall conversion of
AnaeK_3296	COG3459	Glycosyltransferase 36 associated
AnaeK_3298	COG0517	IMP dehydrogenase activity
AnaeK_3298	COG1125	glycine betaine transport
AnaeK_3299	COG1174	glycine betaine transport
AnaeK_3304	COG1404	Belongs to the peptidase S8 family
AnaeK_3306	COG2814	Major facilitator Superfamily
AnaeK_3307	COG2353	YceI-like domain
AnaeK_3312	COG2130	NADP-dependent
AnaeK_3314	COG3387	PFAM Glycoside hydrolase 15-related
AnaeK_3318	COG1993	acr, cog1993
AnaeK_3320	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AnaeK_3324	COG1410	methionine synthase
AnaeK_3324	COG0646	methionine synthase
AnaeK_3327	COG0583	DNA-binding transcription factor activity
AnaeK_3332	COG3436	PFAM IS66 Orf2 family protein
AnaeK_3339	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AnaeK_3351	COG1064	alcohol dehydrogenase
AnaeK_3354	COG1063	alcohol dehydrogenase
AnaeK_3356	COG0583	DNA-binding transcription factor activity
AnaeK_3360	COG1063	alcohol dehydrogenase
AnaeK_3362	COG0006	proline dipeptidase activity
AnaeK_3368	COG1918	ferrous iron import across plasma membrane
AnaeK_3368	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AnaeK_3370	COG0604	alcohol dehydrogenase
AnaeK_3375	COG0516	GMP reductase activity
AnaeK_3376	COG2132	Multicopper oxidase
AnaeK_3378	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
AnaeK_3383	COG1704	LemA family
AnaeK_3384	COG0501	Belongs to the peptidase M48B family
AnaeK_3386	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AnaeK_3393	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AnaeK_3397	COG5337	Spore coat protein CotH
AnaeK_3412	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
AnaeK_3419	COG2204	response regulator
AnaeK_3423	COG5000	phosphorelay sensor kinase activity
AnaeK_3426	COG2252	PERMEase
AnaeK_3427	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AnaeK_3429	COG2521	methyltransferase
AnaeK_3429	COG2136	Putative SAM-dependent methyltransferase
AnaeK_3433	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AnaeK_3433	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AnaeK_3436	COG0544	peptidyl-prolyl cis-trans isomerase activity
AnaeK_3438	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
AnaeK_3440	COG0463	Glycosyl transferase, family 2
AnaeK_3442	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AnaeK_3448	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AnaeK_3452	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AnaeK_3454	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AnaeK_3456	COG0210	DNA helicase
AnaeK_3462	COG0564	pseudouridine synthase activity
AnaeK_3463	COG0625	glutathione transferase activity
AnaeK_3464	COG0612	Peptidase, M16
AnaeK_3466	COG4191	Histidine kinase
AnaeK_3469	COG0739	heme binding
AnaeK_3470	COG0483	inositol monophosphate 1-phosphatase activity
AnaeK_3473	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AnaeK_3476	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AnaeK_3478	COG1619	proteins homologs of microcin C7 resistance protein MccF
AnaeK_3479	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AnaeK_3480	COG0628	permease
AnaeK_3481	COG0545	Peptidyl-prolyl cis-trans isomerase
AnaeK_3493	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AnaeK_3508	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AnaeK_3509	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AnaeK_3510	COG1846	Transcriptional regulator
AnaeK_3516	COG3273	potassium ion transport
AnaeK_3516	COG0471	metal ion transport
AnaeK_3520	COG0123	including yeast histone deacetylase and acetoin utilization protein
AnaeK_3522	COG3123	guanosine phosphorylase activity
AnaeK_3525	COG0587	DNA-directed DNA polymerase activity
AnaeK_3526	COG0730	response to heat
AnaeK_3528	COG2197	response regulator
AnaeK_3529	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AnaeK_3538	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
AnaeK_3540	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AnaeK_3545	COG4206	TonB-dependent receptor
AnaeK_3547	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AnaeK_3548	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AnaeK_3549	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AnaeK_3552	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AnaeK_3553	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AnaeK_3556	COG3852	Histidine kinase
AnaeK_3557	COG3706	GGDEF domain
AnaeK_3557	COG0745	RESPONSE REGULATOR receiver
AnaeK_3560	COG2096	Adenosyltransferase
AnaeK_3562	COG0316	Belongs to the HesB IscA family
AnaeK_3563	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AnaeK_3564	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AnaeK_3566	COG0746	molybdenum cofactor guanylyltransferase activity
AnaeK_3571	COG4106	trans-aconitate 2-methyltransferase activity
AnaeK_3572	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
AnaeK_3573	COG1741	Belongs to the pirin family
AnaeK_3579	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AnaeK_3583	COG1937	Protein conserved in bacteria
AnaeK_3584	COG2217	Heavy metal translocating P-type atpase
AnaeK_3587	COG4941	Belongs to the sigma-70 factor family
AnaeK_3588	COG3795	YCII-related domain
AnaeK_3592	COG0438	transferase activity, transferring glycosyl groups
AnaeK_3594	COG0667	Aldo Keto reductase
AnaeK_3595	COG0583	DNA-binding transcription factor activity
AnaeK_3596	COG3118	belongs to the thioredoxin family
AnaeK_3598	COG1597	lipid kinase activity
AnaeK_3602	COG0840	transmembrane signaling receptor activity
AnaeK_3603	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AnaeK_3606	COG1136	(ABC) transporter
AnaeK_3606	COG0577	efflux transmembrane transporter activity
AnaeK_3607	COG1136	(ABC) transporter
AnaeK_3607	COG0577	efflux transmembrane transporter activity
AnaeK_3609	COG0745	RESPONSE REGULATOR receiver
AnaeK_3614	COG0330	HflC and HflK could
AnaeK_3618	COG3976	FMN-binding domain protein
AnaeK_3618	COG1053	succinate dehydrogenase
AnaeK_3619	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AnaeK_3619	COG0519	Catalyzes the synthesis of GMP from XMP
AnaeK_3620	COG2205	protein histidine kinase activity
AnaeK_3626	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
AnaeK_3631	COG1196	nuclear chromosome segregation
AnaeK_3631	COG0739	heme binding
AnaeK_3631	COG0741	lytic transglycosylase activity
AnaeK_3632	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
AnaeK_3634	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AnaeK_3638	COG2267	carboxylic ester hydrolase activity
AnaeK_3641	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AnaeK_3644	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AnaeK_3645	COG1090	epimerase
AnaeK_3647	COG1214	PFAM Peptidase M22, glycoprotease
AnaeK_3648	COG0750	zinc metalloprotease
AnaeK_3650	COG4589	Belongs to the CDS family
AnaeK_3651	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AnaeK_3660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AnaeK_3661	COG0459	protein refolding
AnaeK_3671	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AnaeK_3680	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AnaeK_3681	COG1183	phosphatidylcholine synthase activity
AnaeK_3682	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
AnaeK_3691	COG1100	Small GTP-binding protein
AnaeK_3693	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
AnaeK_3695	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
AnaeK_3696	COG0590	tRNA wobble adenosine to inosine editing
AnaeK_3699	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AnaeK_3699	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AnaeK_3704	COG2261	transglycosylase associated protein
AnaeK_3712	COG0651	ATP synthesis coupled electron transport
AnaeK_3713	COG0651	ATP synthesis coupled electron transport
AnaeK_3716	COG0651	ATP synthesis coupled electron transport
AnaeK_3717	COG0649	NAD binding
AnaeK_3718	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AnaeK_3722	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AnaeK_3723	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
AnaeK_3726	COG0475	glutathione-regulated potassium exporter activity
AnaeK_3729	COG0739	heme binding
AnaeK_3731	COG0539	negative regulation of cytoplasmic translation
AnaeK_3739	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AnaeK_3741	COG1428	Deoxynucleoside kinase
AnaeK_3746	COG3706	GGDEF domain
AnaeK_3746	COG0745	RESPONSE REGULATOR receiver
AnaeK_3747	COG0484	heat shock protein binding
AnaeK_3749	COG0631	protein serine/threonine phosphatase activity
AnaeK_3750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AnaeK_3754	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AnaeK_3756	COG0477	Major facilitator Superfamily
AnaeK_3757	COG2815	serine threonine protein kinase
AnaeK_3757	COG0515	serine threonine protein kinase
AnaeK_3760	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AnaeK_3761	COG0840	transmembrane signaling receptor activity
AnaeK_3764	COG0626	cystathionine gamma-synthase activity
AnaeK_3767	COG0477	Major facilitator Superfamily
AnaeK_3773	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AnaeK_3775	COG0840	transmembrane signaling receptor activity
AnaeK_3776	COG1902	pentaerythritol trinitrate reductase activity
AnaeK_3778	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AnaeK_3779	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AnaeK_3781	COG5002	protein histidine kinase activity
AnaeK_3781	COG3850	Histidine kinase
AnaeK_3783	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
AnaeK_3785	COG3852	Histidine kinase
AnaeK_3786	COG2204	response regulator
AnaeK_3787	COG1271	oxidase subunit
AnaeK_3788	COG1294	oxidase, subunit
AnaeK_3790	COG2226	methyltransferase
AnaeK_3793	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AnaeK_3797	COG0515	serine threonine protein kinase
AnaeK_3799	COG1024	Enoyl-CoA hydratase
AnaeK_3800	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
AnaeK_3805	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AnaeK_3807	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AnaeK_3811	COG0437	4 iron, 4 sulfur cluster binding
AnaeK_3812	COG2864	formate dehydrogenase
AnaeK_3816	COG1028	Short-chain dehydrogenase reductase Sdr
AnaeK_3822	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AnaeK_3823	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AnaeK_3825	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AnaeK_3834	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AnaeK_3839	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AnaeK_3842	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AnaeK_3844	COG1136	(ABC) transporter
AnaeK_3844	COG0577	efflux transmembrane transporter activity
AnaeK_3846	COG1705	Flagellar rod assembly protein muramidase FlgJ
AnaeK_3846	COG1388	LysM domain
AnaeK_3848	COG2204	response regulator
AnaeK_3853	COG0793	Belongs to the peptidase S41A family
AnaeK_3856	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AnaeK_3862	COG0673	inositol 2-dehydrogenase activity
AnaeK_3864	COG2027	D-alanyl-D-alanine carboxypeptidase
AnaeK_3865	COG0629	single-stranded DNA binding
AnaeK_3869	COG0640	Transcriptional regulator
AnaeK_3887	COG2003	Belongs to the UPF0758 family
AnaeK_3889	COG2353	YceI-like domain
AnaeK_3891	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AnaeK_3898	COG1192	Involved in chromosome partitioning
AnaeK_3903	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AnaeK_3904	COG0047	phosphoribosylformylglycinamidine synthase activity
AnaeK_3908	COG0312	modulator of DNA gyrase
AnaeK_3909	COG0312	modulator of DNA gyrase
AnaeK_3912	COG4221	oxidoreductase activity
AnaeK_3918	COG2205	protein histidine kinase activity
AnaeK_3919	COG0745	RESPONSE REGULATOR receiver
AnaeK_3925	COG3436	PFAM IS66 Orf2 family protein
AnaeK_3946	COG2204	response regulator
AnaeK_3949	COG3852	Histidine kinase
AnaeK_3950	COG0270	DNA (cytosine-5-)-methyltransferase activity
AnaeK_3961	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AnaeK_3965	COG3436	PFAM IS66 Orf2 family protein
AnaeK_3981	COG1595	DNA-templated transcription, initiation
AnaeK_3982	COG1201	RNA secondary structure unwinding
AnaeK_3984	COG1074	ATP-dependent DNA helicase activity
AnaeK_3986	COG0653	protein targeting
AnaeK_3991	COG1032	radical SAM domain protein
AnaeK_3994	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AnaeK_3995	COG0745	RESPONSE REGULATOR receiver
AnaeK_3998	COG0840	transmembrane signaling receptor activity
AnaeK_4000	COG3321	synthase
AnaeK_4000	COG0604	alcohol dehydrogenase
AnaeK_4000	COG1028	Short-chain dehydrogenase reductase Sdr
AnaeK_4001	COG3321	synthase
AnaeK_4001	COG0604	alcohol dehydrogenase
AnaeK_4003	COG2378	regulation of single-species biofilm formation
AnaeK_4009	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AnaeK_4017	COG0640	Transcriptional regulator
AnaeK_4018	COG0798	PFAM Bile acid sodium symporter
AnaeK_4019	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AnaeK_4024	COG0488	(ABC) transporter
AnaeK_4032	COG1322	Protein conserved in bacteria
AnaeK_4036	COG0154	amidase activity
AnaeK_4038	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AnaeK_4039	COG0280	phosphate acetyltransferase
AnaeK_4039	COG0281	malic enzyme
AnaeK_4043	COG1252	NADH dehydrogenase
AnaeK_4048	COG1136	(ABC) transporter
AnaeK_4050	COG2840	Smr protein MutS2
AnaeK_4053	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AnaeK_4054	COG2239	Acts as a magnesium transporter
AnaeK_4059	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AnaeK_4060	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AnaeK_4060	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AnaeK_4061	COG0492	ferredoxin-NADP+ reductase activity
AnaeK_4062	COG0315	cyclic pyranopterin monophosphate synthase activity
AnaeK_4067	COG0405	Gamma-glutamyltransferase
AnaeK_4069	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AnaeK_4070	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AnaeK_4079	COG2379	hydroxypyruvate reductase
AnaeK_4082	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AnaeK_4083	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AnaeK_4093	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AnaeK_4095	COG0670	Belongs to the BI1 family
AnaeK_4097	COG0584	glycerophosphoryl diester phosphodiesterase
AnaeK_4100	COG0488	(ABC) transporter
AnaeK_4101	COG2814	Major facilitator Superfamily
AnaeK_4115	COG3647	Membrane
AnaeK_4118	COG0704	Plays a role in the regulation of phosphate uptake
AnaeK_4119	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AnaeK_4120	COG0581	inorganic phosphate transmembrane transporter activity
AnaeK_4121	COG0573	inorganic phosphate transmembrane transporter activity
AnaeK_4122	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
AnaeK_4124	COG5002	protein histidine kinase activity
AnaeK_4128	COG0116	Belongs to the methyltransferase superfamily
AnaeK_4128	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AnaeK_4137	COG3104	oligopeptide transport
AnaeK_4138	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AnaeK_4139	COG2363	Small membrane protein
AnaeK_4140	COG2154	pterin-4-alpha-carbinolamine dehydratase
AnaeK_4142	COG1408	metallophosphoesterase
AnaeK_4150	COG0811	peptide transport
AnaeK_4154	COG2030	dehydratase
AnaeK_4156	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AnaeK_4159	COG0768	penicillin binding
AnaeK_4160	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AnaeK_4160	COG0574	Belongs to the PEP-utilizing enzyme family
AnaeK_4162	COG0425	Belongs to the sulfur carrier protein TusA family
AnaeK_4165	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AnaeK_4165	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AnaeK_4168	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AnaeK_4171	COG0134	indole-3-glycerol-phosphate synthase activity
AnaeK_4172	COG0135	phosphoribosylanthranilate isomerase activity
AnaeK_4173	COG0133	tryptophan synthase activity
AnaeK_4174	COG0159	tryptophan synthase activity
AnaeK_4176	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
AnaeK_4184	COG1846	Transcriptional regulator
AnaeK_4185	COG0697	spore germination
AnaeK_4187	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
AnaeK_4187	COG0517	IMP dehydrogenase activity
AnaeK_4188	COG0235	Class ii aldolase
AnaeK_4189	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AnaeK_4190	COG0179	Fumarylacetoacetate (FAA) hydrolase
AnaeK_4193	COG0019	diaminopimelate decarboxylase activity
AnaeK_4198	COG0346	lactoylglutathione lyase activity
AnaeK_4200	COG2715	membrane protein required for spore maturation
AnaeK_4201	COG0700	Nucleoside recognition
AnaeK_4210	COG0297	glycogen (starch) synthase activity
AnaeK_4220	COG0438	transferase activity, transferring glycosyl groups
AnaeK_4222	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AnaeK_4224	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AnaeK_4228	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AnaeK_4230	COG1028	Short-chain dehydrogenase reductase Sdr
AnaeK_4232	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AnaeK_4238	COG2076	Multidrug Resistance protein
AnaeK_4246	COG2198	Histidine kinase
AnaeK_4246	COG2205	protein histidine kinase activity
AnaeK_4246	COG0784	Response regulator, receiver
AnaeK_4249	COG1960	acyl-CoA dehydrogenase activity
AnaeK_4252	COG2205	protein histidine kinase activity
AnaeK_4252	COG2198	Histidine kinase
AnaeK_4252	COG0784	Response regulator, receiver
AnaeK_4253	COG0784	Response regulator, receiver
AnaeK_4253	COG2198	Histidine kinase
AnaeK_4253	COG5002	protein histidine kinase activity
AnaeK_4263	COG4580	involved in the transport of maltose and maltodextrins
AnaeK_4265	COG0395	ABC-type sugar transport system, permease component
AnaeK_4266	COG1175	transmembrane transport
AnaeK_4269	COG0366	Alpha amylase catalytic
AnaeK_4278	COG0438	transferase activity, transferring glycosyl groups
AnaeK_4285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AnaeK_4286	COG1136	(ABC) transporter
AnaeK_4286	COG0577	efflux transmembrane transporter activity
AnaeK_4287	COG0577	efflux transmembrane transporter activity
AnaeK_4287	COG1136	(ABC) transporter
AnaeK_4288	COG0577	efflux transmembrane transporter activity
AnaeK_4288	COG1136	(ABC) transporter
AnaeK_4289	COG0681	Belongs to the peptidase S26 family
AnaeK_4292	COG3259	Nickel-dependent hydrogenase
AnaeK_4296	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
AnaeK_4302	COG1560	Kdo2-lipid A biosynthetic process
AnaeK_4303	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
AnaeK_4304	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AnaeK_4308	COG0564	pseudouridine synthase activity
AnaeK_4310	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AnaeK_4315	COG3339	Conserved Protein
AnaeK_4323	COG0457	Tetratricopeptide repeat
AnaeK_4324	COG1674	ftsk spoiiie
AnaeK_4325	COG2885	chlorophyll binding
AnaeK_4325	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
AnaeK_4330	COG0839	Belongs to the complex I subunit 6 family
AnaeK_4333	COG2205	protein histidine kinase activity
AnaeK_4333	COG0784	Response regulator, receiver
AnaeK_4334	COG2153	protein acetylation
AnaeK_4338	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AnaeK_4345	COG2205	protein histidine kinase activity
AnaeK_4345	COG0784	Response regulator, receiver
AnaeK_4352	COG1193	negative regulation of DNA recombination
AnaeK_4353	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AnaeK_4359	COG5002	protein histidine kinase activity
AnaeK_4361	COG0306	phosphate transporter
AnaeK_4362	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AnaeK_4375	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
AnaeK_4379	COG3852	Histidine kinase
AnaeK_4382	COG3852	Histidine kinase
AnaeK_4385	COG0174	glutamine synthetase
AnaeK_4387	COG2076	Multidrug Resistance protein
AnaeK_4392	COG0411	ABC transporter
AnaeK_4394	COG0559	Belongs to the binding-protein-dependent transport system permease family
AnaeK_4396	COG0745	RESPONSE REGULATOR receiver
AnaeK_4399	COG1472	Belongs to the glycosyl hydrolase 3 family
AnaeK_4402	COG0714	Associated with various cellular activities
AnaeK_4408	COG3206	protein involved in exopolysaccharide biosynthesis
AnaeK_4408	COG0489	protein tyrosine kinase activity
AnaeK_4413	COG0438	transferase activity, transferring glycosyl groups
AnaeK_4415	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AnaeK_4420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AnaeK_4421	COG0438	transferase activity, transferring glycosyl groups
AnaeK_4423	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AnaeK_4424	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
AnaeK_4432	COG0463	Glycosyl transferase, family 2
AnaeK_4437	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AnaeK_4442	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AnaeK_4443	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AnaeK_4448	COG3852	Histidine kinase
AnaeK_4449	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
AnaeK_4450	COG1691	(AIR) carboxylase
AnaeK_4452	COG2198	Histidine kinase
AnaeK_4452	COG0643	Histidine kinase
AnaeK_4453	COG2201	protein-glutamate methylesterase activity
AnaeK_4455	COG3290	protein histidine kinase activity
AnaeK_4455	COG0840	transmembrane signaling receptor activity
AnaeK_4456	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AnaeK_4457	COG2205	protein histidine kinase activity
AnaeK_4457	COG2202	Pas domain
AnaeK_4458	COG1100	Small GTP-binding protein
AnaeK_4459	COG1199	ATP-dependent helicase activity
AnaeK_4463	COG0484	heat shock protein binding
AnaeK_4464	COG0443	Heat shock 70 kDa protein
AnaeK_4470	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AnaeK_4471	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AnaeK_4472	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AnaeK_4473	COG0012	GTP binding
AnaeK_4475	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AnaeK_4484	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AnaeK_4488	COG0071	Belongs to the small heat shock protein (HSP20) family
AnaeK_4490	COG1475	DNA binding
AnaeK_4491	COG1192	Involved in chromosome partitioning
AnaeK_4497	COG0594	ribonuclease P activity