locus-tag	class	description
CPRO_00020	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
CPRO_00040	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CPRO_00050	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CPRO_00060	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CPRO_00120	ENOG4105CBD	Diacylglycerol kinase
CPRO_00130	ENOG4107QJE	Chromosome Partitioning Protein
CPRO_00140	ENOG4105FA0	parb-like partition protein
CPRO_00160	ENOG410667J	hydrolase
CPRO_00170	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
CPRO_00210	ENOG4108RVA	ribokinase
CPRO_00230	ENOG4105MT0	Sporulation transcriptional regulator spoiiid
CPRO_00250	ENOG4105MAX	Superoxide reductase
CPRO_00260	ENOG4105CNW	domain protein
CPRO_00270	ENOG4108RAC	Rubrerythrin
CPRO_00280	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
CPRO_00290	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
CPRO_00300	ENOG4105DBV	ornithine carbamoyltransferase
CPRO_00310	ENOG4105C8Y	Acetylornithine aminotransferase
CPRO_00320	ENOG4105CAS	nag kinase
CPRO_00330	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
CPRO_00340	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
CPRO_00350	ENOG4107QM2	Aldo Keto reductase
CPRO_00380	ENOG4105C5S	asparaginyl-tRNA synthetase
CPRO_00390	ENOG4108F19	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
CPRO_00410	ENOG4105C8J	)-transporter
CPRO_00470	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
CPRO_00510	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
CPRO_00580	ENOG4108UUM	single-stranded DNA-binding protein
CPRO_00590	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
CPRO_00600	ENOG4108SAX	Membrane
CPRO_00610	ENOG4105CPF	Cell wall formation (By similarity)
CPRO_00620	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
CPRO_00630	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CPRO_00650	ENOG4105K63	Thioredoxin
CPRO_00670	ENOG4105DAA	L-lactate
CPRO_00680	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
CPRO_00700	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CPRO_00710	ENOG4105KRN	Transcriptional regulator, abrb family
CPRO_00750	ENOG4108Z6B	deaminase
CPRO_00770	ENOG4105C6E	dna polymerase iii
CPRO_00780	ENOG410816I	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
CPRO_00790	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
CPRO_00820	ENOG4105ETU	transcriptional activator (TenA
CPRO_00840	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
CPRO_00940	ENOG4108ZXQ	stage ii sporulation protein r
CPRO_00960	ENOG4108Z5K	methylglyoxal synthase
CPRO_00970	ENOG4105CNI	cell division protein FtsW
CPRO_00990	ENOG4107QMS	site-determining protein
CPRO_01000	ENOG4107YDG	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
CPRO_01010	ENOG4105CJN	penicillin-binding protein
CPRO_01030	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
CPRO_01040	ENOG4105DFF	Rod shape-determining protein mreb
CPRO_01060	ENOG4107SVV	electron transport complex, RnfABCDGE type, B subunit
CPRO_01070	ENOG4105DGN	Electron transport complex
CPRO_01080	ENOG4105DZB	Electron transport complex
CPRO_01100	ENOG4105D6A	Electron transport complex
CPRO_01110	ENOG4107QTR	Required for nitrogen fixation. May be part of a membrane complex functioning as an intermediate in the electron transport to nitrogenase (By similarity)
CPRO_01120	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CPRO_01150	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CPRO_01200	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CPRO_01230	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
CPRO_01240	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CPRO_01260	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CPRO_01280	ENOG410835K	Tripartite ATP-Independent Periplasmic transporter DctQ
CPRO_01290	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CPRO_01340	ENOG4107S1Q	Phosphatase
CPRO_01350	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
CPRO_01360	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
CPRO_01370	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CPRO_01390	ENOG4105EGD	dinuclear metal center protein, YbgI family
CPRO_01400	ENOG4105C22	threonyL-tRNA synthetase
CPRO_01430	ENOG4108W9T	type 1 fimbriae regulatory protein
CPRO_01560	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CPRO_01590	ENOG4108V2W	Carbonate dehydratase
CPRO_01630	ENOG4105C02	permease
CPRO_01640	ENOG4108HRK	Histidine kinase
CPRO_01650	ENOG4105DY9	regulatoR
CPRO_01680	ENOG4105DR4	Methyltransferase
CPRO_01690	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
CPRO_01700	ENOG4107S6Z	Na H antiporter
CPRO_01720	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
CPRO_01730	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CPRO_01740	ENOG4105X71	Membrane
CPRO_01760	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CPRO_01830	ENOG4105C5H	ABC transporter
CPRO_01840	ENOG4105FF6	Modulates transcription in response to changes in cellular NADH NAD( ) redox state (By similarity)
CPRO_01860	ENOG4105C3S	Mate efflux family protein
CPRO_01880	ENOG4108IV0	ABC, transporter
CPRO_01890	ENOG4105C0Z	ABC transporter
CPRO_01900	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
CPRO_01910	ENOG4105C32	Amino acid ABC transporter (Permease)
CPRO_01930	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
CPRO_01940	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
CPRO_01950	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
CPRO_02000	ENOG4105CK7	Sodium proline symporter
CPRO_02010	ENOG4108IG5	Transcriptional regulator
CPRO_02110	ENOG4105CAQ	asparagine synthetase
CPRO_02150	ENOG4105C3G	gtp-binding protein
CPRO_02230	ENOG4108UVJ	appr-1-p processing domain protein
CPRO_02240	ENOG4105MS2	ribosomal subunit Interface protein
CPRO_02280	ENOG4107ZYR	domain protein
CPRO_02290	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CPRO_02310	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
CPRO_02330	ENOG4107Z36	nucleotidyl transferase
CPRO_02360	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
CPRO_02380	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
CPRO_02410	ENOG41069ER	domain protein
CPRO_02420	ENOG4105F8V	Hydrolase, tatD family
CPRO_02430	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
CPRO_02440	ENOG4105C88	aminopeptidase
CPRO_02470	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
CPRO_02490	ENOG4105C8Q	Methyl-accepting chemotaxis
CPRO_02500	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
CPRO_02520	ENOG4105CHH	sulfate transporter
CPRO_02540	ENOG4105UIB	(ABC) transporter
CPRO_02550	ENOG4108JQ9	ABC transporter
CPRO_02570	ENOG4108UPS	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis (By similarity)
CPRO_02600	ENOG4105UQX	Mate efflux family protein
CPRO_02610	ENOG4105PXI	polysaccharide deacetylase
CPRO_02620	ENOG4108UI2	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation (By similarity)
CPRO_02630	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
CPRO_02640	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
CPRO_02660	ENOG4105CY0	Metallo-Beta-Lactamase
CPRO_02670	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CPRO_02680	ENOG4105VCC	30S ribosomal protein S21
CPRO_02690	ENOG4105KTH	gatB Yqey
CPRO_02720	ENOG4108JJB	ABC transporter
CPRO_02730	ENOG41068P3	sporulation protein YqfC
CPRO_02750	ENOG4105C9A	Phoh family
CPRO_02760	ENOG4105CTJ	Metal Dependent Phosphohydrolase
CPRO_02770	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
CPRO_02780	ENOG4105KG3	cytidine deaminase
CPRO_02790	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
CPRO_02810	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
CPRO_02830	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
CPRO_02850	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
CPRO_02870	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
CPRO_02890	ENOG4108ZC9	flagellar basal-body rod protein flgc
CPRO_02900	ENOG4105VQ0	flagellar hook-basal body complex protein fliE
CPRO_02920	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
CPRO_03010	ENOG4107TXC	Transcriptional regulator
CPRO_03070	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
CPRO_03090	ENOG4105FKZ	Methyl-accepting chemotaxis
CPRO_03110	ENOG4105G5W	regulator Fur family
CPRO_03130	ENOG4107R8N	Glycosyl transferase, family 2
CPRO_03170	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
CPRO_03190	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
CPRO_03230	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
CPRO_03270	ENOG4108IG5	Transcriptional regulator
CPRO_03310	ENOG4105K8N	protein family UPF0079, ATPase
CPRO_03320	ENOG41072GX	Peptidase M22 Glycoprotease
CPRO_03330	ENOG410801F	ribosomal-protein-alanine acetyltransferase
CPRO_03340	ENOG4105DAN	ATP-dependent protease
CPRO_03360	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CPRO_03380	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
CPRO_03490	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CPRO_03500	ENOG4105DPN	Oligoendopeptidase f
CPRO_03510	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
CPRO_03600	ENOG4106HK8	GPR1 FUN34 yaaH family protein
CPRO_03620	ENOG41067QW	Transcriptional regulator
CPRO_03640	ENOG41082YX	Transcriptional regulator, arsr family
CPRO_03680	ENOG4105DZ0	fad dependent oxidoreductase
CPRO_03710	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
CPRO_03750	ENOG4105CZV	ABC transporter
CPRO_03770	ENOG4105CE1	Ferrous iron transport protein b
CPRO_03790	ENOG4108JCI	Transcriptional regulator
CPRO_03810	ENOG4105K4I	Scp-like extracellular
CPRO_03870	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
CPRO_03890	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
CPRO_03900	ENOG4105C7B	Threonine dehydratase
CPRO_03910	ENOG4108UZ3	Transporter
CPRO_03930	ENOG4105CNU	cell division protein FtsK
CPRO_03940	ENOG4105CKU	formyltetrahydrofolate synthetase
CPRO_03960	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
CPRO_03970	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
CPRO_03980	ENOG4105CEV	competence damage-inducible protein
CPRO_04000	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
CPRO_04040	ENOG4105X36	(ribosomal) protein
CPRO_04050	ENOG4105K46	50S ribosomal protein l27
CPRO_04070	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
CPRO_04080	ENOG4108KHX	Diguanylate cyclase
CPRO_04110	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
CPRO_04120	ENOG4105C5H	ABC transporter
CPRO_04130	ENOG4105C37	(CBS) domain
CPRO_04140	ENOG4105VRS	hydrolase family 18
CPRO_04160	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CPRO_04170	ENOG41062D9	Histidine kinase
CPRO_04210	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CPRO_04220	ENOG4107QT7	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
CPRO_04230	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CPRO_04260	ENOG4105C9W	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity (By similarity)
CPRO_04270	ENOG4105C3F	Signal peptidase i
CPRO_04290	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
CPRO_04340	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
CPRO_04350	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
CPRO_04370	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CPRO_04380	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
CPRO_04390	ENOG4105D4P	Coproporphyrinogen iii oxidase
CPRO_04400	ENOG4105CUT	histidyl-tRNA synthetase
CPRO_04410	ENOG4105C1A	potassium transporter peripheral membrane
CPRO_04420	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CPRO_04440	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
CPRO_04450	ENOG4107QQR	Sporulation
CPRO_04460	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
CPRO_04510	ENOG4107S0N	DJ-1 family
CPRO_04540	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
CPRO_04560	ENOG4105N5T	Radical SAM Protein
CPRO_04580	ENOG4107QZB	decarboxylase
CPRO_04600	ENOG41090I5	UPF0735 ACT domain-containing protein
CPRO_04610	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
CPRO_04620	ENOG4105CFH	Aspartokinase
CPRO_04630	ENOG4105WEF	catalase
CPRO_04700	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
CPRO_04710	ENOG4105WEF	catalase
CPRO_04740	ENOG4105VKD	bioY protein
CPRO_04760	ENOG4105C1G	acyl-Coa dehydrogenase
CPRO_04770	ENOG4105BZJ	Electron transfer flavoprotein
CPRO_04780	ENOG4105C10	Electron transfer flavoprotein
CPRO_04820	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
CPRO_04840	ENOG4107R7I	amino acid
CPRO_04850	ENOG4105VYW	UPF0251 protein
CPRO_04870	ENOG4105BZG	amino acid carrier protein
CPRO_04880	ENOG4105BZG	amino acid carrier protein
CPRO_04890	ENOG4105BZG	amino acid carrier protein
CPRO_04910	ENOG4105BZF	Glycosyl transferase (Group 1
CPRO_04920	ENOG4105ENA	helicase
CPRO_04940	ENOG4105CJ1	ABC, transporter
CPRO_04990	ENOG41073R8	VanW family
CPRO_05010	ENOG4105CHM	Aminotransferase
CPRO_05030	ENOG4105C37	(CBS) domain
CPRO_05050	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
CPRO_05160	ENOG4105CE1	Ferrous iron transport protein b
CPRO_05190	ENOG4105C8Q	Methyl-accepting chemotaxis
CPRO_05210	ENOG4108Z29	Flavodoxin
CPRO_05290	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CPRO_05300	ENOG4105D98	threonine synthase
CPRO_05320	ENOG4105CV1	Transketolase (EC 2.2.1.1)
CPRO_05340	ENOG4105VUC	UPF0237 protein
CPRO_05350	ENOG4105CAG	UPF0210 protein
CPRO_05370	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
CPRO_05390	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
CPRO_05400	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
CPRO_05410	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
CPRO_05430	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
CPRO_05450	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
CPRO_05460	ENOG41082SA	50s ribosomal protein l29
CPRO_05470	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
CPRO_05480	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
CPRO_05490	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
CPRO_05500	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
CPRO_05510	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
CPRO_05520	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
CPRO_05530	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
CPRO_05550	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
CPRO_05560	ENOG4105VPB	50S ribosomal protein L30
CPRO_05570	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
CPRO_05580	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
CPRO_05590	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
CPRO_05620	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
CPRO_05640	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
CPRO_05650	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
CPRO_05660	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CPRO_05670	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
CPRO_05680	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CPRO_05690	ENOG4108ZT0	50S ribosomal protein l17
CPRO_05720	ENOG4108JJB	ABC transporter
CPRO_05730	ENOG4108JJB	ABC transporter
CPRO_05740	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
CPRO_05750	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
CPRO_05760	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
CPRO_05770	ENOG4108UJD	30S ribosomal protein S9
CPRO_05780	ENOG4105JHY	Membrane
CPRO_05790	ENOG4108IGT	Dipeptidase
CPRO_05810	ENOG410812S	Rna-binding protein
CPRO_05830	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
CPRO_05860	ENOG4105BZ8	glutamate synthase
CPRO_05870	ENOG4105C8Q	Methyl-accepting chemotaxis
CPRO_05930	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CPRO_05940	ENOG41060GV	RNA binding s1 domain protein
CPRO_05960	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CPRO_05970	ENOG4108UMI	ABC transporter, permease
CPRO_05980	ENOG4105D01	(LipO)protein
CPRO_05990	ENOG4105CH2	amidohydrolase
CPRO_06020	ENOG4105D2N	Aldolase
CPRO_06070	ENOG4105EMN	RNA polymerase sigma factor
CPRO_06090	ENOG4108IQ6	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
CPRO_06100	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
CPRO_06120	ENOG4105CIH	Imidazole acetol-phosphate transaminase
CPRO_06130	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
CPRO_06140	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
CPRO_06150	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
CPRO_06160	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
CPRO_06170	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
CPRO_06190	ENOG4108V06	Glutathione peroxidase
CPRO_06200	ENOG4105K56	Transcriptional regulator
CPRO_06370	ENOG4105C08	Histidine kinase
CPRO_06380	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
CPRO_06450	ENOG4105C28	cystathionine
CPRO_06460	ENOG4107RSM	transcriptional regulator
CPRO_06500	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
CPRO_06530	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
CPRO_06540	ENOG4105CHR	reductase
CPRO_06560	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
CPRO_06570	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
CPRO_06580	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
CPRO_06590	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
CPRO_06630	ENOG4105CEF	Initiates the rapid degradation of small, acid-soluble proteins during spore germination (By similarity)
CPRO_06640	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
CPRO_06660	ENOG4105CMW	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis (By similarity)
CPRO_06670	ENOG4105CZG	Phosphotransfer between the C1 and C5 carbon atoms of pentose (By similarity)
CPRO_06680	ENOG4107Y3V	-acetyltransferase
CPRO_06690	ENOG4105DAP	Nicotinate phosphoribosyltransferase
CPRO_06700	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
CPRO_06710	ENOG4107QIV	Cytochrome c biogenesis protein
CPRO_06730	ENOG4108Z5V	transcriptional regulator, merr family
CPRO_06750	ENOG4108UYI	beta-alanyl-CoA ammonia lyase
CPRO_06810	ENOG4108Z66	YbaK ebsC protein
CPRO_06860	ENOG4105DKQ	ROK family
CPRO_06880	ENOG4105CYC	Transferase
CPRO_06890	ENOG4108Z6B	deaminase
CPRO_06900	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CPRO_06910	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
CPRO_06920	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
CPRO_06950	ENOG4108RAC	Rubrerythrin
CPRO_06960	ENOG4105PW4	Sugar fermentation stimulation protein homolog
CPRO_06970	ENOG4105DZ1	carboxypeptidase
CPRO_06980	ENOG41064RH	membrane protein YliF
CPRO_07040	ENOG4107RWR	Sodium hydrogen exchanger
CPRO_07070	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
CPRO_07110	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
CPRO_07130	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CPRO_07140	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
CPRO_07160	ENOG4105DXX	methyltransferase
CPRO_07170	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
CPRO_07220	ENOG4105QD4	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CPRO_07250	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
CPRO_07260	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
CPRO_07270	ENOG4105M56	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
CPRO_07280	ENOG4105CHM	Aminotransferase
CPRO_07300	ENOG4107S9D	Alpha beta hydrolase
CPRO_07310	ENOG4105CU9	asparagine synthetase A
CPRO_07340	ENOG4105JFG	SpoIID LytB domain protein
CPRO_07360	ENOG4105C7K	acetolactate synthase
CPRO_07370	ENOG4108ZP8	Acetolactate synthase small subunit
CPRO_07380	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
CPRO_07400	ENOG4105C9M	aspartyl-trna synthetase
CPRO_07420	ENOG4108EU4	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CPRO_07560	ENOG4105C2M	dna polymerase I
CPRO_07620	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CPRO_07630	ENOG4105VEQ	Cold shock protein
CPRO_07680	ENOG41061CV	Terminase small subunit 
CPRO_07990	ENOG4107RNS	bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase 3'-nucleotidase periplasmic
CPRO_08000	ENOG4105CGH	5'-nucleotidase
CPRO_08050	ENOG4107QMS	site-determining protein
CPRO_08070	ENOG4105KXX	peptidase s58 dmpa
CPRO_08080	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CPRO_08110	ENOG4105K67	small basic protein
CPRO_08120	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
CPRO_08130	ENOG4107S17	Phosphate-binding protein
CPRO_08140	ENOG4105C8U	phosphate abc transporter
CPRO_08150	ENOG4105E2Z	phosphate ABC transporter (Permease
CPRO_08170	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
CPRO_08200	ENOG4105BZU	Histidine kinase
CPRO_08230	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
CPRO_08250	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
CPRO_08330	ENOG410687F	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
CPRO_08340	ENOG4105CFP	Peptidase U32
CPRO_08360	ENOG4105CJN	penicillin-binding protein
CPRO_08400	ENOG4108IIG	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
CPRO_08410	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CPRO_08420	ENOG4105BZU	Histidine kinase
CPRO_08440	ENOG4105WD1	Membrane
CPRO_08460	ENOG4108JJ9	ABC, transporter
CPRO_08610	ENOG4105MFU	Protein of unknown function (DUF2634)
CPRO_08620	ENOG41066EA	baseplate J family protein
CPRO_08710	ENOG4108J5H	Homocysteine s-methyltransferase
CPRO_08800	ENOG4105WRB	Hydrogenase assembly chaperone hypC hupF
CPRO_08810	ENOG4105CQS	hydrogenase expression formation protein HypD
CPRO_08850	ENOG4105DPX	Hydrogenase, large subunit
CPRO_08860	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CPRO_08870	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CPRO_08880	ENOG4107SDT	Homocitrate synthase
CPRO_08900	ENOG4105D2X	ABC transporter substrate-binding protein
CPRO_08910	ENOG4105C2M	dna polymerase I
CPRO_08920	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
CPRO_08940	ENOG4107RRN	ABC transporter substrate-binding protein
CPRO_08950	ENOG4107Z60	histidine triad (HIT) protein
CPRO_08960	ENOG4108SVB	resolvase
CPRO_09090	ENOG4107ZE5	PPIases accelerate the folding of proteins
CPRO_09110	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CPRO_09130	ENOG4105M6F	mutator MutT protein
CPRO_09160	ENOG4105W5Q	DNA repair protein (RadC
CPRO_09180	ENOG4105C31	Tryptophanyl-tRNA synthetase
CPRO_09190	ENOG4105C0H	protease
CPRO_09230	ENOG4105CAQ	asparagine synthetase
CPRO_09260	ENOG4105KDM	Diguanylate cyclase with gaf sensor
CPRO_09280	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CPRO_09290	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
CPRO_09320	ENOG4105C8Q	Methyl-accepting chemotaxis
CPRO_09370	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
CPRO_09380	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
CPRO_09390	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CPRO_09400	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
CPRO_09410	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
CPRO_09420	ENOG4105FDP	GntR family transcriptional regulator
CPRO_09430	ENOG4105C01	Dihydroxy-acid dehydratase
CPRO_09440	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CPRO_09460	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CPRO_09480	ENOG4108E1C	hydrolase
CPRO_09490	ENOG4105BZU	Histidine kinase
CPRO_09550	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
CPRO_09580	ENOG4105CEM	UPF0597 protein
CPRO_09600	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CPRO_09610	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
CPRO_09640	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CPRO_09660	ENOG4108UHU	Aldolase
CPRO_09680	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
CPRO_09690	ENOG4105DEI	Mannitol dehydrogenase
CPRO_09700	ENOG4105GQU	Trap dicarboxylate transporter, dctp subunit
CPRO_09710	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
CPRO_09720	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CPRO_09730	ENOG4105CPQ	Dehydrogenase
CPRO_09740	ENOG4107XBN	GntR Family Transcriptional Regulator
CPRO_09760	ENOG4105DNP	FAD linked oxidase domain protein
CPRO_09770	ENOG4105BZU	Histidine kinase
CPRO_09780	ENOG4105WH1	Two component transcriptional regulator luxr family
CPRO_09840	ENOG4106KNT	transcriptional regulator
CPRO_09850	ENOG4107UEK	pfkb domain protein
CPRO_09870	ENOG4105C2J	ABC transporter
CPRO_09880	ENOG4105CNN	ABC, transporter
CPRO_09890	ENOG4105DKQ	ROK family
CPRO_09900	ENOG4105D2N	Aldolase
CPRO_09910	ENOG4105CTQ	phosphohexokinase
CPRO_09930	ENOG4108RZE	Tetr family transcriptional regulator
CPRO_10050	ENOG4108DMH	HTH_ARAC
CPRO_10060	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
CPRO_10100	ENOG4105BZU	Histidine kinase
CPRO_10110	ENOG4105E5Q	amino acid AbC transporter
CPRO_10120	ENOG4105DRP	amino acid AbC transporter
CPRO_10130	ENOG4105CDA	abc transporter atp-binding protein
CPRO_10140	ENOG4105EAB	amino acid AbC transporter
CPRO_10170	ENOG4105JQZ	Methyltransferase
CPRO_10180	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
CPRO_10190	ENOG4105C28	cystathionine
CPRO_10220	ENOG4105D01	(LipO)protein
CPRO_10240	ENOG4108UMI	ABC transporter, permease
CPRO_10270	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
CPRO_10280	ENOG4105DDK	oxidoreductase, beta subunit
CPRO_10290	ENOG4105DZS	Phenylacetate-CoA ligase
CPRO_10310	ENOG4108ZF1	Transcriptional regulator, BadM Rrf2 family
CPRO_10340	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CPRO_10350	ENOG4105CUZ	uba thif-type nad fad binding protein
CPRO_10360	ENOG4105C3J	Cysteine desulfurase
CPRO_10370	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
CPRO_10380	ENOG4105D6E	homoserine dehydrogenase
CPRO_10400	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CPRO_10450	ENOG4108JYK	Dehydrogenase
CPRO_10460	ENOG4105CPP	Dehydrogenase, E1 component
CPRO_10470	ENOG4107QKR	Dehydrogenase
CPRO_10490	ENOG4105C8Q	Methyl-accepting chemotaxis
CPRO_10510	ENOG4105C7J	ABC transporter, permease
CPRO_10520	ENOG4105D5T	phosphonate abc transporter
CPRO_10550	ENOG4108UIN	ybak prolyl-trna synthetase associated region
CPRO_10590	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
CPRO_10610	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
CPRO_10620	ENOG4105CAQ	asparagine synthetase
CPRO_10640	ENOG4105DZ2	Transcriptional regulator
CPRO_10650	ENOG4108EKI	Dehydrogenase
CPRO_10660	ENOG4105C1J	atp-dependent rna helicase
CPRO_10670	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
CPRO_10680	ENOG4105KT7	mgtC SapB transporter
CPRO_10710	ENOG41090VF	Stage v sporulation protein ac
CPRO_10740	ENOG4105CDY	transcriptional regulatory protein
CPRO_10750	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
CPRO_10930	ENOG4108TFU	terminase (Small subunit)
CPRO_11170	ENOG4105DZ6	Band 7 protein
CPRO_11230	ENOG4105EB3	Histidine kinase
CPRO_11240	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CPRO_11270	ENOG4105EB2	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CPRO_11310	ENOG4105EEM	helicase
CPRO_11320	ENOG4105SUT	Transcriptional Regulator AraC Family
CPRO_11390	ENOG4108D32	Methyltransferase
CPRO_11410	ENOG41086D8	Transcriptional regulator
CPRO_11460	ENOG4105BZ1	(ABC) transporter
CPRO_11490	ENOG4105DY9	regulatoR
CPRO_11510	ENOG4108V0P	LemA family
CPRO_11550	ENOG4105EWM	Histidine kinase
CPRO_11560	ENOG4105C19	ABC transporter
CPRO_11600	ENOG4108UZE	carboxy-peptidase
CPRO_11640	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
CPRO_11670	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
CPRO_11720	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
CPRO_11740	ENOG4105C9Q	fumarate hydratase class II
CPRO_11750	ENOG4108SHJ	s-layer protein
CPRO_11760	ENOG4105C6K	Malic enzyme
CPRO_11770	ENOG4107XJU	UPF0178 protein
CPRO_11790	ENOG4108RWN	rrna methyltransferase
CPRO_11810	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
CPRO_11840	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
CPRO_11850	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
CPRO_11860	ENOG4105CQC	Prephenate dehydratase
CPRO_11870	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
CPRO_11880	ENOG4105CHM	Aminotransferase
CPRO_11890	ENOG4108V6E	Cell division protein mraZ
CPRO_11910	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
CPRO_11930	ENOG4105CJN	penicillin-binding protein
CPRO_11940	ENOG4105CJN	penicillin-binding protein
CPRO_11960	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
CPRO_11970	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
CPRO_11980	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
CPRO_11990	ENOG4105CNI	cell division protein FtsW
CPRO_12010	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
CPRO_12030	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
CPRO_12040	ENOG4105DCG	PHP domain protein
CPRO_12050	ENOG4105KGF	protein, YerC YecD
CPRO_12070	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
CPRO_12080	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
CPRO_12120	ENOG4105BZU	Histidine kinase
CPRO_12170	ENOG4105C8Q	Methyl-accepting chemotaxis
CPRO_12180	ENOG4105VTR	Integrase
CPRO_12230	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
CPRO_12240	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CPRO_12260	ENOG4105HF9	Inherit from COG: pyridine nucleotide-disulfide oxidoreductase
CPRO_12280	ENOG4107YTP	response regulator receiver protein
CPRO_12320	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
CPRO_12360	ENOG4108ESE	uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center
CPRO_12370	ENOG4105BZG	amino acid carrier protein
CPRO_12390	ENOG4105BZU	Histidine kinase
CPRO_12400	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CPRO_12430	ENOG41067QW	Transcriptional regulator
CPRO_12470	ENOG4108IAB	Phoh family
CPRO_12490	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
CPRO_12500	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CPRO_12510	ENOG4105EPR	degv family
CPRO_12520	ENOG4108VJ1	Transcriptional regulator (CarD family
CPRO_12530	ENOG4105CTP	PilT protein domain protein
CPRO_12540	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
CPRO_12550	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CPRO_12560	ENOG4105VEQ	Cold shock protein
CPRO_12580	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CPRO_12590	ENOG4105BZU	Histidine kinase
CPRO_12620	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
CPRO_12630	ENOG4106AXJ	AraC family transcriptional regulator
CPRO_12640	ENOG410631K	Membrane
CPRO_12670	ENOG4105D29	Helix-turn-helix type 11 domain protein
CPRO_12690	ENOG4105EPI	acetyltransferase, (GNAT) family
CPRO_12720	ENOG4105D1Z	hydroxypyruvate reductase
CPRO_12730	ENOG4108ZQX	ybak prolyl-trna synthetase
CPRO_12740	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CPRO_12760	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
CPRO_12780	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
CPRO_12800	ENOG4105DZ1	carboxypeptidase
CPRO_12820	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CPRO_12830	ENOG4105CXI	aluminum resistance protein
CPRO_12840	ENOG4108HED	Type II restriction
CPRO_12850	ENOG4105CKP	Polysaccharide Biosynthesis Protein
CPRO_12860	ENOG4107R7I	amino acid
CPRO_12870	ENOG4105SC1	monovalent cation H antiporter subunit E
CPRO_12930	ENOG4108JPZ	Monovalent cation H antiporter subunit D
CPRO_12940	ENOG4108JPZ	Monovalent cation H antiporter subunit D
CPRO_12960	ENOG4108JPZ	Monovalent cation H antiporter subunit D
CPRO_13010	ENOG41064RH	membrane protein YliF
CPRO_13120	ENOG4108Y4K	DNA-binding transcriptional activator
CPRO_13150	ENOG4105GJD	protein, conserved in bacteria
CPRO_13420	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
CPRO_13440	ENOG4105EYG	tyrosine recombinase. Not involved in the cutting and rejoining of the recombining DNA molecules on dif(SL) site (By similarity)
CPRO_13480	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
CPRO_13490	ENOG4105C7N	Xanthine uracil vitamin C permease
CPRO_13500	ENOG4105CTQ	phosphohexokinase
CPRO_13520	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
CPRO_13530	ENOG4108YBP	pseudouridine synthase
CPRO_13540	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
CPRO_13570	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
CPRO_13610	ENOG4105DF9	Lipoate-protein, ligase
CPRO_13630	ENOG4108C33	Resolvase
CPRO_13730	ENOG4105KRN	Transcriptional regulator, abrb family
CPRO_13970	ENOG4105E4C	Lytic transglycosylase catalytic
CPRO_14160	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
CPRO_14250	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
CPRO_14260	ENOG4108RAV	Conserved protein
CPRO_14270	ENOG4108NMV	polysaccharide deacetylase
CPRO_14280	ENOG4105DD7	kinase (PfkB family
CPRO_14360	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
CPRO_14370	ENOG4105CZX	twitching motility protein
CPRO_14390	ENOG4105C8Q	Methyl-accepting chemotaxis
CPRO_14400	ENOG4105K63	Thioredoxin
CPRO_14420	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
CPRO_14430	ENOG4107RSM	transcriptional regulator
CPRO_14460	ENOG4105CE1	Ferrous iron transport protein b
CPRO_14490	ENOG4105C8Q	Methyl-accepting chemotaxis
CPRO_14510	ENOG4105D8V	Glucose sorbosone dehydrogenase
CPRO_14540	ENOG4107QW8	radical SAM domain protein
CPRO_14620	ENOG4105DA5	(ABC) transporter
CPRO_14630	ENOG41086KC	Transcriptional regulator
CPRO_14640	ENOG4105C8Y	Acetylornithine aminotransferase
CPRO_14650	ENOG4107SG5	Dehydrogenase
CPRO_14660	ENOG4107S6Z	Na H antiporter
CPRO_14670	ENOG4105EMN	RNA polymerase sigma factor
CPRO_14750	ENOG4105CE1	Ferrous iron transport protein b
CPRO_14800	ENOG4105F32	YngK protein
CPRO_14810	ENOG4105E2X	shikimate dehydrogenase
CPRO_14840	ENOG4108U05	Transcriptional regulator
CPRO_14900	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
CPRO_14930	ENOG4107R4J	Chloride channel
CPRO_14940	ENOG4108HW3	(ABC) transporter
CPRO_14950	ENOG4105E5Q	amino acid AbC transporter
CPRO_14960	ENOG4105CDA	abc transporter atp-binding protein
CPRO_14970	ENOG4108115	UPF0145 protein
CPRO_14980	ENOG4107QUT	magnesium and cobalt transport protein CorA
CPRO_14990	ENOG4105C22	threonyL-tRNA synthetase
CPRO_15000	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
CPRO_15010	ENOG4105VJV	50s ribosomal protein L35
CPRO_15020	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
CPRO_15060	ENOG4108JPW	Aminotransferase
CPRO_15080	ENOG4107SXA	Phosphorylase
CPRO_15110	ENOG4105D7K	pfkb domain protein
CPRO_15120	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
CPRO_15140	ENOG4107RFY	SbcCD D subunit
CPRO_15150	ENOG4105EYH	Exonuclease
CPRO_15160	ENOG4105EYH	Exonuclease
CPRO_15180	ENOG4108S0H	Dipicolinic acid synthetase, b subunit
CPRO_15190	ENOG4108IQK	o-acetylhomoserine
CPRO_15200	ENOG4105CVG	Homoserine O-transsuccinylase
CPRO_15210	ENOG4105JFG	SpoIID LytB domain protein
CPRO_15230	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
CPRO_15240	ENOG4105D1H	recombination factor protein RarA
CPRO_15250	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
CPRO_15260	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
CPRO_15280	ENOG4105BZU	Histidine kinase
CPRO_15290	ENOG4105CI3	gtp-binding protein typa
CPRO_15320	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
CPRO_15330	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
CPRO_15340	ENOG4105D4A	Cell wall formation (By similarity)
CPRO_15350	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
CPRO_15360	ENOG4105CIE	May be required for sporulation (By similarity)
CPRO_15370	ENOG4105KRI	phosphocarrier protein (HPr
CPRO_15380	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
CPRO_15390	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
CPRO_15400	ENOG4105VIE	preprotein translocase, subunit YajC
CPRO_15420	ENOG4108JQ9	ABC transporter
CPRO_15460	ENOG4105DU0	nucleoside hydrolase
CPRO_15480	ENOG4105KY8	Rubrerythrin
CPRO_15510	ENOG41063SB	peptidase
CPRO_15520	ENOG4105W8Z	4'-phosphopantetheinyl transferase
CPRO_15530	ENOG4105C8T	Leucyl-tRNA synthetase
CPRO_15540	ENOG4105BZ1	(ABC) transporter
CPRO_15550	ENOG4105BZ1	(ABC) transporter
CPRO_15560	ENOG4108U05	Transcriptional regulator
CPRO_15570	ENOG4108UT2	hemolysin iii
CPRO_15590	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
CPRO_15600	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
CPRO_15620	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
CPRO_15630	ENOG4105KNE	Phosphatidate cytidylyltransferase
CPRO_15640	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
CPRO_15650	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
CPRO_15660	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
CPRO_15670	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
CPRO_15680	ENOG4105CE9	30S ribosomal protein S2
CPRO_15690	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
CPRO_15710	ENOG4105C0P	Mg chelatase subunit ChlI
CPRO_15730	ENOG4105C8Q	Methyl-accepting chemotaxis
CPRO_15740	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CPRO_15760	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
CPRO_15790	ENOG4108KMM	Diguanylate cyclase
CPRO_15810	ENOG4105DJ4	phosphatidylserine decarboxylase
CPRO_15820	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
CPRO_15860	ENOG4105CHM	Aminotransferase
CPRO_15870	ENOG4105CYC	Transferase
CPRO_15890	ENOG4105WGB	oxidoreductase, delta subunit
CPRO_15900	ENOG4105DRR	Transcriptional regulator, GntR family
CPRO_15930	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
CPRO_15940	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
CPRO_15960	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CPRO_15970	ENOG4105CUZ	uba thif-type nad fad binding protein
CPRO_15980	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
CPRO_16000	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
CPRO_16010	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
CPRO_16030	ENOG4105C5X	domain protein
CPRO_16060	ENOG4105ST3	Transcriptional regulator
CPRO_16070	ENOG4105D3R	alkyl hydroperoxide reductase
CPRO_16140	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
CPRO_16150	ENOG4105CY2	Citrate transporter
CPRO_16160	ENOG4105E39	Enoyl-CoA hydratase
CPRO_16170	ENOG4107R0K	CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons (By similarity)
CPRO_16190	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
CPRO_16220	ENOG4105WEF	catalase
CPRO_16260	ENOG4108UYI	beta-alanyl-CoA ammonia lyase
CPRO_16270	ENOG4107SG5	Dehydrogenase
CPRO_16290	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
CPRO_16300	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
CPRO_16310	ENOG4107KMQ	bfd domain protein (2fe-2s)-binding domain protein
CPRO_16350	ENOG4105C8J	)-transporter
CPRO_16380	ENOG4108MEJ	flavin reductase domain protein
CPRO_16390	ENOG4105C8Q	Methyl-accepting chemotaxis
CPRO_16390	ENOG4105C8Q	Methyl-accepting chemotaxis
CPRO_16410	ENOG4108594	Permease of the drug metabolite transporter
CPRO_16420	ENOG4105KVH	Transcriptional regulator
CPRO_16440	ENOG4105C08	Histidine kinase
CPRO_16450	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
CPRO_16470	ENOG4107VEG	TrkA-N domain protein
CPRO_16480	ENOG4105C1A	potassium transporter peripheral membrane
CPRO_16490	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
CPRO_16500	ENOG4108XHQ	(2Fe-2S)-binding domain protein
CPRO_16520	ENOG4105C7W	Xanthine dehydrogenase
CPRO_16660	ENOG4105DNP	FAD linked oxidase domain protein
CPRO_16720	ENOG4107S21	permease
CPRO_16740	ENOG4105D6J	arsenicaL-resistance protein
CPRO_16760	ENOG4105C4B	ABC transporter, permease
CPRO_16770	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
CPRO_16790	ENOG4105UEI	Transcriptional Regulator AraC Family
CPRO_16820	ENOG4108YBA	Histidine kinase
CPRO_16830	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CPRO_16870	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
CPRO_16880	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
CPRO_16910	ENOG4107V40	secretion protein, HlyD family
CPRO_16930	ENOG4105KXX	peptidase s58 dmpa
CPRO_16960	ENOG4108IA2	Sodium pantothenate symporter
CPRO_16980	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
CPRO_16990	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
CPRO_17000	ENOG4108FUF	Transcriptional regulator, IclR family
CPRO_17010	ENOG4105D58	Diguanylate phosphodiesterase
CPRO_17040	ENOG4105C8Q	Methyl-accepting chemotaxis
CPRO_17150	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CPRO_17230	ENOG4105C3I	Nad-dependent epimerase dehydratase
CPRO_17240	ENOG41083UI	stage II sporulation protein
CPRO_17250	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CPRO_17280	ENOG4108JJA	ABC, transporter
CPRO_17310	ENOG4108KHX	Diguanylate cyclase
CPRO_17390	ENOG4105GPN	Uncharacterized conserved protein (DUF2294)
CPRO_17440	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
CPRO_17470	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
CPRO_17480	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CPRO_17490	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
CPRO_17580	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CPRO_17720	ENOG4105C4R	Atp-dependent dna helicase
CPRO_17730	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
CPRO_17840	ENOG4105CIZ	coA-substrate-specific enzyme activase
CPRO_17910	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
CPRO_17920	ENOG4105VCQ	rubredoxin
CPRO_17960	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
CPRO_17980	ENOG4108ESE	uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center
CPRO_18030	ENOG4105EJ7	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (By similarity)
CPRO_18090	ENOG4108MVM	Transposase
CPRO_18110	ENOG410890F	Dynamin family
CPRO_18120	ENOG4105CIN	aminoacyl-histidine dipeptidase
CPRO_18130	ENOG4105CSX	c4-dicarboxylate anaerobic carrier
CPRO_18140	ENOG4107QSE	Dipeptidase
CPRO_18160	ENOG4105BZU	Histidine kinase
CPRO_18170	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
CPRO_18180	ENOG4105D3R	alkyl hydroperoxide reductase
CPRO_18190	ENOG4108UZ3	Transporter
CPRO_18220	ENOG4105D5G	Transposase
CPRO_18230	ENOG4105EFZ	amidohydrolase
CPRO_18270	ENOG4108MVM	Transposase
CPRO_18290	ENOG4105EKQ	RNA-directed DNA polymerase
CPRO_18310	ENOG4105K5B	UPF0225 protein
CPRO_18330	ENOG4105C4R	Atp-dependent dna helicase
CPRO_18340	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
CPRO_18520	ENOG4105F9F	transposase
CPRO_18550	ENOG4105VEM	Conserved domain protein
CPRO_18570	ENOG4107QMH	DNA methylase
CPRO_18660	ENOG4105MU5	relaxase mobilization nuclease domain protein
CPRO_18700	ENOG4105EKQ	RNA-directed DNA polymerase
CPRO_18750	ENOG4105MRD	Phage derived protein Gp49-like (DUF891)
CPRO_18770	ENOG4105C9U	ATP-dependent DNA helicase RecQ
CPRO_18810	ENOG4105K4H	Nlp p60 protein
CPRO_18830	ENOG4105EKQ	RNA-directed DNA polymerase
CPRO_18950	ENOG4105FA0	parb-like partition protein
CPRO_18960	ENOG4107QJE	Chromosome Partitioning Protein
CPRO_18980	ENOG4107Y5K	Resolvase
CPRO_19070	ENOG4105ST3	Transcriptional regulator
CPRO_19080	ENOG4108RS6	transposase
CPRO_19110	ENOG4105C5X	domain protein
CPRO_19180	ENOG4105K4H	Nlp p60 protein
CPRO_19190	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CPRO_19230	ENOG4105C5X	domain protein
CPRO_19250	ENOG4107TXC	Transcriptional regulator
CPRO_19390	ENOG4105D29	Helix-turn-helix type 11 domain protein
CPRO_19400	ENOG4105D29	Helix-turn-helix type 11 domain protein
CPRO_19420	ENOG4105C5H	ABC transporter
CPRO_19430	ENOG4105C5H	ABC transporter
CPRO_19450	ENOG4105CJ1	ABC, transporter
CPRO_19550	ENOG4105EKQ	RNA-directed DNA polymerase
CPRO_19640	ENOG4105K4W	Could be involved in septation (By similarity)
CPRO_19710	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CPRO_19720	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CPRO_19840	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CPRO_19900	ENOG4105EKQ	RNA-directed DNA polymerase
CPRO_19920	ENOG4105CB5	ATP-dependent DNA helicase recG
CPRO_20040	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
CPRO_20070	ENOG4105EQI	Metal Dependent Phosphohydrolase
CPRO_20130	ENOG4105E65	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CPRO_20170	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
CPRO_20180	ENOG4105EAM	Na Pi-cotransporter
CPRO_20190	ENOG4105CFH	Aspartokinase
CPRO_20220	ENOG4105CYW	agmatinase
CPRO_20230	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
CPRO_20240	ENOG4105CXN	decarboxylase
CPRO_20260	ENOG4105DND	Transcriptional regulator
CPRO_20270	ENOG4105CPQ	Dehydrogenase
CPRO_20280	ENOG4105BZU	Histidine kinase
CPRO_20290	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
CPRO_20310	ENOG4107R4J	Chloride channel
CPRO_20320	ENOG4105WWK	YheO domain protein
CPRO_20330	ENOG4106HK8	GPR1 FUN34 yaaH family protein
CPRO_20340	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
CPRO_20350	ENOG4107Z8R	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
CPRO_20360	ENOG4105VB6	UPF0109 protein
CPRO_20370	ENOG4105K5M	30s ribosomal protein S16
CPRO_20400	ENOG4108TGR	phosphatase
CPRO_20430	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
CPRO_20450	ENOG4108FUT	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system) (By similarity)
CPRO_20460	ENOG4105EJQ	L-serine dehydratase
CPRO_20480	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
CPRO_20490	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
CPRO_20500	ENOG4105C3M	thioredoxin reductase
CPRO_20510	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CPRO_20520	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
CPRO_20540	ENOG4108IMY	Transcriptional regulator
CPRO_20550	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
CPRO_20560	ENOG4105XBY	Regulates arginine biosynthesis genes (By similarity)
CPRO_20570	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
CPRO_20580	ENOG4105DX0	Hemolysin A
CPRO_20590	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
CPRO_20620	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CPRO_20630	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
CPRO_20650	ENOG4108ZSR	alkaline shock protein
CPRO_20700	ENOG4105KQ4	Stage iii sporulation protein ad
CPRO_20710	ENOG4108CQH	stage III sporulation protein AC
CPRO_20730	ENOG4105CD2	stage iii sporulation protein aa
CPRO_20740	ENOG4107Y7X	LytTR
CPRO_20800	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
CPRO_20840	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
CPRO_20860	ENOG4105BZU	Histidine kinase
CPRO_20870	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CPRO_20890	ENOG4105DZ1	carboxypeptidase
CPRO_20900	ENOG4105K4H	Nlp p60 protein
CPRO_20910	ENOG4105BZ1	(ABC) transporter
CPRO_20950	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CPRO_20960	ENOG4105D03	DNA-3-methyladenine glycosylase II
CPRO_20970	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
CPRO_20980	ENOG4107QHE	Choloylglycine hydrolase
CPRO_21000	ENOG4105BZU	Histidine kinase
CPRO_21210	ENOG4108C33	Resolvase
CPRO_21420	ENOG4105CT2	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CPRO_21450	ENOG4105DMD	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CPRO_21510	ENOG4107SJI	Dehydrogenase
CPRO_21520	ENOG4105BZ8	glutamate synthase
CPRO_21540	ENOG4105EW8	cytosine purines, uracil, thiamine, allantoin permease
CPRO_21560	ENOG4108Z5V	transcriptional regulator, merr family
CPRO_21590	ENOG4108UYI	beta-alanyl-CoA ammonia lyase
CPRO_21600	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
CPRO_21670	ENOG4106A3R	peptidase
CPRO_21690	ENOG4105D7Q	type ii secretion system
CPRO_21700	ENOG4105CZX	twitching motility protein
CPRO_21710	ENOG4107QHF	type ii secretion system protein e
CPRO_21770	ENOG4105K56	Transcriptional regulator
CPRO_21780	ENOG4105CFP	Peptidase U32
CPRO_21790	ENOG4108VQJ	O-methyltransferase
CPRO_21800	ENOG4105HHA	aminodeoxychorismate lyase
CPRO_21880	ENOG4105CEN	a g-specific adenine glycosylase
CPRO_21890	ENOG4105TMB	Formate nitrite transporter
CPRO_21900	ENOG4105BZC	d-serine deaminase
CPRO_21920	ENOG4105C08	Histidine kinase
CPRO_21930	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
CPRO_21990	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
CPRO_22000	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
CPRO_22010	ENOG4105CD3	dihydroorotase
CPRO_22020	ENOG4105CXT	aspartate transcarbamylase
CPRO_22030	ENOG4105C34	Pseudouridine synthase
CPRO_22040	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
CPRO_22080	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
CPRO_22090	ENOG4105DFA	alanine racemase domain protein
CPRO_22130	ENOG4106Z86	ATP-nad acox kinase
CPRO_22150	ENOG4107RUY	(E1 component), alpha subunit
CPRO_22190	ENOG4105DXU	ATPase. Has a role at an early stage in the morphogenesis of the spore coat (By similarity)
CPRO_22250	ENOG4105KVH	Transcriptional regulator
CPRO_22290	ENOG4108JCI	Transcriptional regulator
CPRO_22300	ENOG4105C6N	Formate acetyltransferase
CPRO_22310	ENOG4105F1A	Pyruvate formate-lyase
CPRO_22320	ENOG4105CPI	Metal Dependent Phosphohydrolase
CPRO_22360	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
CPRO_22370	ENOG4105BZG	amino acid carrier protein
CPRO_22380	ENOG4105C28	cystathionine
CPRO_22410	ENOG4105QIV	RNA polymerase
CPRO_22420	ENOG4105M0M	Tetracycline resistance protein
CPRO_22430	ENOG4105C2N	RNA methyltransferase TrmH family group 3
CPRO_22450	ENOG4105C8N	cysteinyl-tRNA synthetase
CPRO_22460	ENOG4105D7W	serine acetyltransferase
CPRO_22470	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
CPRO_22610	ENOG4105DI5	UPF0365 protein
CPRO_22640	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
CPRO_22650	ENOG4108DWA	Nad synthetase
CPRO_22660	ENOG4105BZU	Histidine kinase
CPRO_22680	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CPRO_22690	ENOG4105C98	muts2 protein
CPRO_22700	ENOG4105DMC	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 3
CPRO_22720	ENOG4105CHR	reductase
CPRO_22780	ENOG4105VB9	50S ribosomal protein l28
CPRO_22800	ENOG4105DJV	ribulose-phosphate 3-epimerase
CPRO_22810	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CPRO_22820	ENOG4105D9P	serine threonine protein kinase
CPRO_22820	ENOG4105D9P	serine threonine protein kinase
CPRO_22840	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
CPRO_22850	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
CPRO_22870	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
CPRO_22880	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
CPRO_22890	ENOG4105C25	Primosomal protein n'
CPRO_22900	ENOG4105C25	Primosomal protein n'
CPRO_22920	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
CPRO_22940	ENOG4105DSJ	YicC domain protein
CPRO_22950	ENOG4105F23	Fibronectin-binding protein
CPRO_22980	ENOG4105C03	ribonuclease
CPRO_23000	ENOG4105DR5	peptidase
CPRO_23020	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
CPRO_23030	ENOG4105EWC	Purine nucleoside phosphorylase
CPRO_23050	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
CPRO_23060	ENOG4105BZ1	(ABC) transporter
CPRO_23080	ENOG4108UYE	Lactoylglutathione lyase
CPRO_23360	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
CPRO_23380	ENOG4107QKR	Dehydrogenase
CPRO_23390	ENOG4105CPP	Dehydrogenase, E1 component
CPRO_23400	ENOG4107RUY	(E1 component), alpha subunit
CPRO_23410	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CPRO_23460	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
CPRO_23470	ENOG4107QNG	Phosphoribosylglycinamide synthetase
CPRO_23480	ENOG4105DC1	bifunctional purine biosynthesis protein purh
CPRO_23510	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
CPRO_23520	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
CPRO_23540	ENOG4105C8V	SAICAR synthetase
CPRO_23550	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
CPRO_23560	ENOG4105CD3	dihydroorotase
CPRO_23580	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
CPRO_23590	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
CPRO_23600	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
CPRO_23620	ENOG4105CXT	aspartate transcarbamylase
CPRO_23680	ENOG4105C02	permease
CPRO_23690	ENOG4105CIN	aminoacyl-histidine dipeptidase
CPRO_23700	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
CPRO_23710	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
CPRO_23740	ENOG4105CBS	Chea signal transduction histidine kinase
CPRO_23750	ENOG4108IJ2	phosphate acetyltransferase
CPRO_23780	ENOG41067VY	50S ribosomal protein L32
CPRO_23790	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
CPRO_23800	ENOG4105CDE	UPF0348 protein
CPRO_23810	ENOG4105H20	Sporulation integral membrane protein YlbJ
CPRO_23830	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
CPRO_23840	ENOG4106H78	methyltransferase
CPRO_23880	ENOG4105C0B	DNA polymerase III (alpha subunit)
CPRO_23890	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CPRO_23900	ENOG4105C19	ABC transporter
CPRO_23910	ENOG4107X8C	Efflux transporter RND family MFP subunit
CPRO_23940	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
CPRO_24000	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CPRO_24330	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CPRO_24400	ENOG4105KRN	Transcriptional regulator, abrb family
CPRO_24480	ENOG41068WC	Domain of unknown function (DUF955)
CPRO_24590	ENOG4107ZBH	radical SAM domain protein
CPRO_24620	ENOG4105VEQ	Cold shock protein
CPRO_24660	ENOG4105DP4	dak2 domain fusion protein ylov
CPRO_24670	ENOG4108ZAA	Alkaline-shock protein
CPRO_24680	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
CPRO_24700	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
CPRO_24710	ENOG4105CHR	reductase
CPRO_24720	ENOG4108RS6	transposase
CPRO_24880	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
CPRO_24890	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
CPRO_24900	ENOG4107R7Y	intracellular protease Pfpi family
CPRO_24910	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
CPRO_24920	ENOG4105MZ9	stage II sporulation protein m
CPRO_24950	ENOG4108IGT	Dipeptidase
CPRO_24960	ENOG4107QQR	Sporulation
CPRO_24970	ENOG4105S1Z	Stage IV sporulation protein B
CPRO_25010	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
CPRO_25020	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
CPRO_25030	ENOG4105CP7	Triose-phosphate isomerase
CPRO_25050	ENOG4105BZA	Phosphoglycerate kinase
CPRO_25100	ENOG4107R34	abc transporter permease protein
CPRO_25120	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CPRO_25140	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
CPRO_25150	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
CPRO_25160	ENOG4105WG9	Conserved Protein
CPRO_25170	ENOG4105C1V	Peptidase, M16
CPRO_25180	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
CPRO_25190	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
CPRO_25210	ENOG4105DTN	riboflavin biosynthesis protein ribF
CPRO_25220	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
CPRO_25250	ENOG4107EEM	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
CPRO_25270	ENOG4105VZN	Nucleic-acid-binding protein implicated in transcription termination
CPRO_25280	ENOG4105CHV	Transcription elongation factor NusA
CPRO_25290	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
CPRO_25300	ENOG4108UQV	Membrane
CPRO_25310	ENOG4105CDA	abc transporter atp-binding protein
CPRO_25320	ENOG4105E5Q	amino acid AbC transporter
CPRO_25330	ENOG4106PMH	Extracellular solute-binding protein family 3
CPRO_25340	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
CPRO_25350	ENOG4107R0W	ABC transporter
CPRO_25380	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
CPRO_25390	ENOG4105F6E	Acyl-transferase
CPRO_25400	ENOG4105CAT	Cytidine monophosphate kinase
CPRO_25410	ENOG4105CBX	hi0933 family
CPRO_25420	ENOG4105CVJ	phosphoglycerate mutase
CPRO_25430	ENOG4105FE9	pseudouridine synthase
CPRO_25440	ENOG4105DZ1	carboxypeptidase
CPRO_25460	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
CPRO_25470	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
CPRO_25530	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
CPRO_25570	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
CPRO_25580	ENOG4105CX6	glutaminyL-tRNA synthetase
CPRO_25620	ENOG4105D22	carbon starvation protein
CPRO_25630	ENOG4105CGK	Exodeoxyribonuclease III
CPRO_25660	ENOG4105KJF	protein tyrosine phosphatase
CPRO_25670	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
CPRO_25690	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
CPRO_25700	ENOG4105DK0	Indole-3-glycerol phosphate synthase
CPRO_25710	ENOG4108I0Q	anthranilate phosphoribosyltransferase
CPRO_25720	ENOG4105DDQ	anthranilate synthase
CPRO_25730	ENOG4105CRQ	synthase (Component I)
CPRO_25740	ENOG4105JAB	phenazine biosynthesis protein, phzf family
CPRO_25750	ENOG4107U9B	transcriptional regulator
CPRO_25770	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
CPRO_25780	ENOG4105CFG	Acts as a chaperone (By similarity)
CPRO_25790	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
CPRO_25810	ENOG4105CSA	Coproporphyrinogen iii oxidase
CPRO_25820	ENOG4107T7U	Sulfatase
CPRO_25840	ENOG4107RCH	Diaminopropionate ammonia-lyase
CPRO_25860	ENOG4105VZ8	Transcriptional regulator
CPRO_25910	ENOG4107RAQ	aminopeptidase
CPRO_25920	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
CPRO_25950	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
CPRO_25970	ENOG4108IUQ	atp-dependent protease
CPRO_25980	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
CPRO_25990	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
CPRO_26000	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
CPRO_26010	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
CPRO_26020	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
CPRO_26040	ENOG4108IG5	Transcriptional regulator
CPRO_26050	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CPRO_26060	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
CPRO_26090	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
CPRO_26110	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
CPRO_26130	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
CPRO_26170	ENOG4105D82	Glutamate dehydrogenase
CPRO_26190	ENOG4105CN1	protease
CPRO_26200	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
CPRO_26210	ENOG4105CAK	Cell division ATP-binding protein ftsE
CPRO_26220	ENOG4105G9B	Transcriptional regulator
CPRO_26230	ENOG4108JYZ	YitT family
CPRO_26280	ENOG4105CPK	Glycosyl transferase (Group 1
CPRO_26290	ENOG4105CJR	Integral membrane protein (MviN
CPRO_26340	ENOG4105DBI	uridine monophosphokinase
CPRO_26350	ENOG4108KGH	TRANSCRIPTIONal
CPRO_26360	ENOG4108KGH	TRANSCRIPTIONal
CPRO_26380	ENOG4105C8J	)-transporter
CPRO_26390	ENOG4105CJW	magnesium transporter
CPRO_26410	ENOG4105CDU	Replicative dna helicase
CPRO_26420	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
CPRO_26430	ENOG4105BZR	domain protein
CPRO_26470	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
CPRO_26480	ENOG4105C02	permease
CPRO_26510	ENOG4108M14	stage v sporulation protein t
CPRO_26520	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
CPRO_26530	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
CPRO_26560	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
CPRO_26580	ENOG4105CN5	Metallo-Beta-Lactamase
CPRO_26590	ENOG41068XD	UPF0473 protein
CPRO_26610	ENOG4105VBH	UPF0297 protein
CPRO_26620	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
CPRO_26630	ENOG4108HCJ	Hydrolase
CPRO_26660	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
CPRO_26670	ENOG4108Z86	Glutamine amidotransferase
CPRO_26680	ENOG4105D8X	mechanosensitive ion channel
CPRO_26730	ENOG4105C59	p-type ATPase
CPRO_26740	ENOG4107YCR	Transcriptional regulator, ARSR family
CPRO_26750	ENOG4105DUM	transcriptional regulator, lysR family
CPRO_26780	ENOG4108JA2	transcriptioN-repair coupling factor
CPRO_26790	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
CPRO_26800	ENOG4105C5I	Dehydrogenase
CPRO_26820	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
CPRO_26830	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
CPRO_26850	ENOG4105CNB	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
CPRO_26860	ENOG4105DFU	Cell wall formation (By similarity)
CPRO_26870	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
CPRO_26880	ENOG4105Q2H	domain protein
CPRO_26890	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CPRO_26930	ENOG4105BZU	Histidine kinase
CPRO_26940	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
CPRO_26950	ENOG4105BZU	Histidine kinase
CPRO_26980	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
CPRO_26990	ENOG41060K3	Methyltransferase
CPRO_27000	ENOG4105MA4	psp1 domain protein
CPRO_27010	ENOG4105C6E	dna polymerase iii
CPRO_27020	ENOG4105X0R	protein from nitrogen regulatory protein P-II
CPRO_27030	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
CPRO_27040	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
CPRO_27060	ENOG4105ESV	Glycosyl transferase, family 4
CPRO_27080	ENOG4108YZG	isomerase
CPRO_27090	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
CPRO_27100	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
CPRO_27120	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
CPRO_27150	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
CPRO_27170	ENOG4105K59	histidine triad (HIT) protein
CPRO_27210	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
CPRO_27230	ENOG4105KAV	tspo and mbr like protein
CPRO_27240	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
CPRO_27260	ENOG4105MJ2	Competence protein
CPRO_27270	ENOG4105C7H	Helicase, RecD TraA family
CPRO_27280	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
CPRO_27330	ENOG4105BZU	Histidine kinase
CPRO_27350	ENOG4105EUB	pirin domain protein
CPRO_27370	ENOG4108ZJ4	polysaccharide deacetylase
CPRO_27390	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
CPRO_27400	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
CPRO_27420	ENOG4105C2W	permease
CPRO_27430	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
CPRO_27440	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
CPRO_27450	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
CPRO_27480	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
CPRO_27510	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
CPRO_27520	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
CPRO_27560	ENOG4108ESE	uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center
CPRO_27570	ENOG4107QYV	phosphohexose isomerase
CPRO_27590	ENOG4105DRR	Transcriptional regulator, GntR family
CPRO_27600	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
CPRO_27610	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
CPRO_27620	ENOG4108R6K	riboflavin synthase, subunit alpha
CPRO_27630	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
CPRO_27640	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
CPRO_27650	ENOG4105F4G	Membrane
CPRO_27670	ENOG4105C6T	cysteine synthase
CPRO_27710	ENOG4107SDU	Methyl-accepting chemotaxis
CPRO_28080	ENOG4105DWU	Membrane
CPRO_28100	ENOG4105C5W	Aldolase
CPRO_28110	ENOG4105C5H	ABC transporter
CPRO_28130	ENOG4105CUZ	uba thif-type nad fad binding protein
CPRO_28160	ENOG4105C10	Electron transfer flavoprotein
CPRO_28170	ENOG4105BZJ	Electron transfer flavoprotein
CPRO_28180	ENOG4105C1G	acyl-Coa dehydrogenase
CPRO_28190	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
CPRO_28200	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
CPRO_28210	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CPRO_28230	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
CPRO_28250	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
CPRO_28260	ENOG4105CAK	Cell division ATP-binding protein ftsE
CPRO_28300	ENOG4107RT6	flagellar hook-associated
CPRO_28310	ENOG4107QJE	Chromosome Partitioning Protein
CPRO_28330	ENOG4107R88	Chemotaxis protein (CheV)
CPRO_28340	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
CPRO_28350	ENOG4107PHP	CheC --inhibitor of MCP methylation
CPRO_28360	ENOG4108JQA	flagellar
CPRO_28370	ENOG4105CGA	flagellar basal-body rod protein FlgG
CPRO_28380	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
CPRO_28390	ENOG4105D7B	Flagellar biosynthesis protein flha
CPRO_28400	ENOG4105D00	flagellar biosynthetic protein flhB
CPRO_28410	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
CPRO_28420	ENOG4105VS8	Flagellar biosynthetic protein fliq
CPRO_28430	ENOG4105CN7	Flagellar biosynthetic protein FliP
CPRO_28450	ENOG4107YTP	response regulator receiver protein
CPRO_28460	ENOG4105DD5	Flagellar motor switch protein
CPRO_28480	ENOG4106VK6	Flagellar motor protein
CPRO_28490	ENOG4105E14	MotA TolQ exbB proton channel
CPRO_28510	ENOG4108JQA	flagellar
CPRO_28550	ENOG4108SHJ	s-layer protein
CPRO_28570	ENOG4105D00	flagellar biosynthetic protein flhB
CPRO_28590	ENOG4105CBS	Chea signal transduction histidine kinase
CPRO_28600	ENOG4108V3W	Chemotaxis protein, CheW
CPRO_28610	ENOG4105BZU	Histidine kinase
CPRO_28620	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
CPRO_28680	ENOG4105W5T	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum (By similarity)
CPRO_28690	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
CPRO_28710	ENOG4105CDA	abc transporter atp-binding protein
CPRO_28720	ENOG4105E5Q	amino acid AbC transporter
CPRO_28730	ENOG4105E89	ABC transporter
CPRO_28750	ENOG4105C3F	Signal peptidase i
CPRO_28900	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
CPRO_28910	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
CPRO_28920	ENOG4105CBJ	Metal-dependent enzyme
CPRO_28930	ENOG41082DI	50s ribosomal protein l31
CPRO_28940	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
CPRO_28990	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
CPRO_29010	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
CPRO_29090	ENOG41082I2	s4 domain protein
CPRO_29100	ENOG4105K70	DNA-binding protein
CPRO_29110	ENOG4105DXN	mazG family
CPRO_29120	ENOG4105CDJ	oxidoreductase FAD NAD(P)-binding domain protein
CPRO_29130	ENOG4105BZ8	glutamate synthase
CPRO_29140	ENOG4105C5X	domain protein
CPRO_29150	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
CPRO_29170	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
CPRO_29180	ENOG4107YUK	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
CPRO_29190	ENOG4107RBI	VanW family
CPRO_29200	ENOG4105D01	(LipO)protein
CPRO_29210	ENOG4108UMI	ABC transporter, permease
CPRO_29220	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
CPRO_29240	ENOG4108KGH	TRANSCRIPTIONal
CPRO_29260	ENOG4105DWF	phosphomethylpyrimidine kinase
CPRO_29310	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
CPRO_29320	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
CPRO_29330	ENOG4108JQ1	Dehydrogenase
CPRO_29360	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
CPRO_29370	ENOG4105ERH	Fumarylacetoacetate hydrolase
CPRO_29380	ENOG4105CDH	Citrulline--aspartate ligase
CPRO_29390	ENOG4105CH7	arginosuccinase
CPRO_29430	ENOG4107XGZ	Hydrolase
CPRO_29450	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CPRO_29460	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
CPRO_29470	ENOG4108JCI	Transcriptional regulator
CPRO_29480	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
CPRO_29490	ENOG4105F38	ABC transporter, permease
CPRO_29500	ENOG4105D38	putrescine abc transporter
CPRO_29510	ENOG4107RUE	extracellular solute-binding protein family 1
CPRO_29550	ENOG4108790	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
CPRO_29580	ENOG4105CXN	decarboxylase
CPRO_29610	ENOG4108IJ8	ABC transporter
CPRO_29620	ENOG4105E90	ABC transporter
CPRO_29630	ENOG4105R40	Glycine betaine carnitine choline
CPRO_29650	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
CPRO_29670	ENOG4108IG5	Transcriptional regulator
CPRO_29680	ENOG4107V2S	Transcriptional regulator
CPRO_29690	ENOG4105HMI	Membrane
CPRO_29730	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
CPRO_29750	ENOG4105C8B	TIGR00159 family
CPRO_29760	ENOG4105CRK	lysyL-tRNA synthetase
CPRO_29770	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
CPRO_29820	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
CPRO_29830	ENOG4105II7	pyrroline-5-carboxylate reductase
CPRO_29840	ENOG41080E8	Transcriptional regulator, Spx MgsR family
CPRO_29850	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
CPRO_29870	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
CPRO_29880	ENOG4107ZXI	Rhomboid family
CPRO_29930	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
CPRO_29940	ENOG4105CH2	amidohydrolase
CPRO_30060	ENOG4105US7	Histidine kinase
CPRO_30070	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
CPRO_30200	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
CPRO_30220	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
CPRO_30230	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
CPRO_30240	ENOG4108Z7S	Single-stranded nucleic acid binding R3H domain-containing protein
CPRO_30250	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
CPRO_30260	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
CPRO_30270	ENOG4105M7T	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)