locus-tag	class	description
NQ528_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NQ528_00010	COG0592	DNA-directed DNA polymerase activity
NQ528_00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NQ528_00030	COG0187	DNA topoisomerase II activity
NQ528_00045	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NQ528_00055	COG1283	sodium-dependent phosphate transmembrane transporter activity
NQ528_00065	COG0494	nUDIX hydrolase
NQ528_00075	COG1464	Belongs to the NlpA lipoprotein family
NQ528_00080	COG2011	ABC-type metal ion transport system permease component
NQ528_00085	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NQ528_00090	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
NQ528_00100	COG0513	Belongs to the DEAD box helicase family
NQ528_00105	COG1058	Belongs to the CinA family
NQ528_00105	COG1546	Belongs to the CinA family
NQ528_00115	COG1854	S-ribosylhomocysteine lyase activity
NQ528_00130	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NQ528_00140	COG3855	fructose 1,6-bisphosphate 1-phosphatase activity
NQ528_00155	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
NQ528_00170	COG0590	tRNA wobble adenosine to inosine editing
NQ528_00185	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
NQ528_00190	COG1687	branched-chain amino acid
NQ528_00195	COG0456	acetyltransferase
NQ528_00200	COG0708	Exodeoxyribonuclease III
NQ528_00210	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
NQ528_00220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NQ528_00240	COG1592	Rubrerythrin
NQ528_00245	COG1028	Short-chain dehydrogenase reductase Sdr
NQ528_00255	COG1609	Transcriptional regulator
NQ528_00260	COG0673	inositol 2-dehydrogenase activity
NQ528_00310	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
NQ528_00315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NQ528_00320	COG0800	Aldolase
NQ528_00330	COG2081	HI0933 family
NQ528_00335	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NQ528_00340	COG0363	glucosamine-6-phosphate deaminase activity
NQ528_00350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NQ528_00350	COG1263	PTS System
NQ528_00370	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NQ528_00375	COG1263	PTS System
NQ528_00375	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NQ528_00375	COG2190	(PTS) system
NQ528_00380	COG3711	transcriptional antiterminator
NQ528_00385	COG1609	Transcriptional regulator
NQ528_00405	COG0656	L-ascorbic acid biosynthetic process
NQ528_00410	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NQ528_00410	COG1918	ferrous iron import across plasma membrane
NQ528_00420	COG1307	EDD domain protein, DegV family
NQ528_00430	COG0697	spore germination
NQ528_00435	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NQ528_00445	COG4608	Belongs to the ABC transporter superfamily
NQ528_00450	COG0444	Belongs to the ABC transporter superfamily
NQ528_00455	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NQ528_00470	COG0747	negative chemotaxis
NQ528_00495	COG2827	Endonuclease containing a URI domain
NQ528_00530	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
NQ528_00535	COG0149	triose-phosphate isomerase activity
NQ528_00540	COG0126	phosphoglycerate kinase activity
NQ528_00645	COG0268	Binds directly to 16S ribosomal RNA
NQ528_00660	COG0671	phosphoesterase, PA-phosphatase related
NQ528_00670	COG0423	glycine-tRNA ligase activity
NQ528_00710	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NQ528_00760	COG0582	viral genome integration into host DNA
NQ528_00800	COG1373	ATPase (AAA superfamily
NQ528_00805	COG0582	viral genome integration into host DNA
NQ528_00935	COG1475	DNA binding
NQ528_00940	COG3969	phosphoadenosine phosphosulfate
NQ528_00945	COG0840	transmembrane signaling receptor activity
NQ528_00960	COG1396	sequence-specific DNA binding
NQ528_00970	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
NQ528_00995	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ528_01000	COG1129	ABC transporter
NQ528_01005	COG1879	ABC-type sugar transport system periplasmic component
NQ528_01010	COG1070	Carbohydrate kinase
NQ528_01015	COG1082	Xylose isomerase domain protein TIM barrel
NQ528_01020	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NQ528_01025	COG3959	Transketolase, thiamine diphosphate binding domain
NQ528_01030	COG1349	DNA-binding transcription factor activity
NQ528_01040	COG0346	lactoylglutathione lyase activity
NQ528_01045	COG1966	Carbon starvation protein
NQ528_01050	COG3022	response to hydroperoxide
NQ528_01075	COG0210	DNA helicase
NQ528_01095	COG1132	(ABC) transporter
NQ528_01100	COG1132	(ABC) transporter
NQ528_01125	COG1349	DNA-binding transcription factor activity
NQ528_01130	COG0626	cystathionine gamma-synthase activity
NQ528_01145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NQ528_01150	COG0444	Belongs to the ABC transporter superfamily
NQ528_01155	COG4608	Belongs to the ABC transporter superfamily
NQ528_01175	COG0583	DNA-binding transcription factor activity
NQ528_01185	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NQ528_01195	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NQ528_01220	COG3835	regulator
NQ528_01230	COG2610	gluconate transmembrane transporter activity
NQ528_01240	COG1929	Belongs to the glycerate kinase type-1 family
NQ528_01245	COG1331	Highly conserved protein containing a thioredoxin domain
NQ528_01250	COG0641	radical SAM
NQ528_01255	COG1609	Transcriptional regulator
NQ528_01260	COG3119	arylsulfatase activity
NQ528_01285	COG2059	Chromate
NQ528_01305	COG0573	inorganic phosphate transmembrane transporter activity
NQ528_01310	COG0581	inorganic phosphate transmembrane transporter activity
NQ528_01315	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NQ528_01320	COG0704	Plays a role in the regulation of phosphate uptake
NQ528_01325	COG0745	RESPONSE REGULATOR receiver
NQ528_01330	COG5002	protein histidine kinase activity
NQ528_01350	COG1079	Belongs to the binding-protein-dependent transport system permease family
NQ528_01355	COG4603	Belongs to the binding-protein-dependent transport system permease family
NQ528_01360	COG3845	ABC transporter
NQ528_01370	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NQ528_01380	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NQ528_01385	COG0779	Required for maturation of 30S ribosomal subunits
NQ528_01390	COG0195	Participates in both transcription termination and antitermination
NQ528_01395	COG2740	Nucleic-acid-binding protein implicated in transcription termination
NQ528_01405	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NQ528_01415	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
NQ528_01425	COG0196	riboflavin kinase activity
NQ528_01435	COG1185	polyribonucleotide nucleotidyltransferase activity
NQ528_01440	COG1253	flavin adenine dinucleotide binding
NQ528_01450	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
NQ528_01460	COG1940	carbohydrate kinase activity
NQ528_01465	COG1940	carbohydrate kinase activity
NQ528_01470	COG0673	inositol 2-dehydrogenase activity
NQ528_01480	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ528_01485	COG1879	ABC-type sugar transport system periplasmic component
NQ528_01490	COG1129	ABC transporter
NQ528_01500	COG0372	Belongs to the citrate synthase family
NQ528_01505	COG2385	sporulation resulting in formation of a cellular spore
NQ528_01520	COG0436	Aminotransferase
NQ528_01535	COG1979	alcohol dehydrogenase
NQ528_01540	COG0167	dihydroorotate dehydrogenase activity
NQ528_01550	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NQ528_01555	COG0402	S-adenosylhomocysteine deaminase activity
NQ528_01580	COG4895	conserved protein (DUF2196)
NQ528_01585	COG1393	Belongs to the ArsC family
NQ528_01590	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NQ528_01605	COG0789	Transcriptional regulator
NQ528_01605	COG4978	Transcriptional regulator
NQ528_01630	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
NQ528_01640	COG3842	ATPase activity
NQ528_01645	COG1176	ABC-type spermidine putrescine transport system, permease component I
NQ528_01650	COG1177	transmembrane transport
NQ528_01665	COG4251	negative regulation of phosphorylation
NQ528_01685	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NQ528_01690	COG3959	Transketolase, thiamine diphosphate binding domain
NQ528_01720	COG1070	Carbohydrate kinase
NQ528_01725	COG1063	alcohol dehydrogenase
NQ528_01735	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ528_01740	COG1129	ABC transporter
NQ528_01745	COG1940	carbohydrate kinase activity
NQ528_01760	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
NQ528_01775	COG0277	FAD linked oxidase domain protein
NQ528_01785	COG2086	electron transfer activity
NQ528_01790	COG0179	Fumarylacetoacetate (FAA) hydrolase
NQ528_01810	COG0559	Belongs to the binding-protein-dependent transport system permease family
NQ528_01815	COG0683	leucine binding
NQ528_01820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NQ528_01835	COG2186	Transcriptional regulator
NQ528_01845	COG0840	transmembrane signaling receptor activity
NQ528_01880	COG0446	pyridine nucleotide-disulphide oxidoreductase
NQ528_01885	COG0300	oxidoreductase activity
NQ528_01890	COG1309	transcriptional regulator
NQ528_01905	COG0148	phosphopyruvate hydratase activity
NQ528_01910	COG0716	FMN binding
NQ528_01970	COG2333	competence protein COMEC
NQ528_01970	COG0658	competence protein
NQ528_01975	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
NQ528_01980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NQ528_01990	COG1573	uracil-dna glycosylase
NQ528_01995	COG4869	propanediol catabolic process
NQ528_02000	COG0745	RESPONSE REGULATOR receiver
NQ528_02005	COG5002	protein histidine kinase activity
NQ528_02010	COG0733	neurotransmitter:sodium symporter activity
NQ528_02030	COG3409	Peptidoglycan-binding domain 1 protein
NQ528_02030	COG3757	hydrolase, family 25
NQ528_02220	COG2842	Transposition protein
NQ528_02245	COG3617	BRO family, N-terminal domain
NQ528_02260	COG4948	Mandelate Racemase Muconate Lactonizing
NQ528_02265	COG4948	Mandelate Racemase Muconate Lactonizing
NQ528_02275	COG4948	Mandelate Racemase Muconate Lactonizing
NQ528_02285	COG2186	Transcriptional regulator
NQ528_02295	COG1131	(ABC) transporter
NQ528_02300	COG1725	Transcriptional regulator
NQ528_02325	COG1968	undecaprenyl-diphosphatase activity
NQ528_02330	COG0740	serine-type endopeptidase activity
NQ528_02335	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NQ528_02355	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NQ528_02360	COG2246	polysaccharide biosynthetic process
NQ528_02380	COG1216	Glycosyl transferase, family 2
NQ528_02390	COG1215	transferase activity, transferring glycosyl groups
NQ528_02420	COG0463	Glycosyl transferase, family 2
NQ528_02430	COG0673	inositol 2-dehydrogenase activity
NQ528_02435	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
NQ528_02440	COG0473	3-isopropylmalate dehydrogenase activity
NQ528_02460	COG0012	GTP binding
NQ528_02465	COG0745	RESPONSE REGULATOR receiver
NQ528_02470	COG3850	Histidine kinase
NQ528_02470	COG5002	protein histidine kinase activity
NQ528_02475	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NQ528_02500	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
NQ528_02505	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
NQ528_02510	COG0228	four-way junction DNA binding
NQ528_02515	COG1837	Belongs to the UPF0109 family
NQ528_02520	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NQ528_02525	COG0336	Belongs to the RNA methyltransferase TrmD family
NQ528_02530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NQ528_02535	COG0322	excinuclease ABC activity
NQ528_02540	COG0742	ribosomal rna small subunit methyltransferase
NQ528_02545	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NQ528_02555	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
NQ528_02560	COG2137	regulation of response to DNA damage stimulus
NQ528_02565	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NQ528_02570	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NQ528_02575	COG1045	serine acetyltransferase
NQ528_02580	COG0215	cysteine-tRNA ligase activity
NQ528_02600	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
NQ528_02620	COG1063	alcohol dehydrogenase
NQ528_02625	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ528_02630	COG1129	ABC transporter
NQ528_02635	COG1879	ABC-type sugar transport system periplasmic component
NQ528_02645	COG1105	Belongs to the carbohydrate kinase PfkB family
NQ528_02655	COG2376	Dihydroxyacetone kinase
NQ528_02660	COG1349	DNA-binding transcription factor activity
NQ528_02675	COG2820	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis
NQ528_02680	COG1079	Belongs to the binding-protein-dependent transport system permease family
NQ528_02685	COG4603	Belongs to the binding-protein-dependent transport system permease family
NQ528_02690	COG3845	ABC transporter
NQ528_02695	COG1744	ABC transporter substrate-binding protein PnrA-like
NQ528_02705	COG1349	DNA-binding transcription factor activity
NQ528_02720	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NQ528_02725	COG2610	gluconate transmembrane transporter activity
NQ528_02730	COG3048	D-serine ammonia-lyase activity
NQ528_02735	COG3875	lactate racemase activity
NQ528_02750	COG1757	Na H antiporter
NQ528_02755	COG0745	RESPONSE REGULATOR receiver
NQ528_02760	COG2205	protein histidine kinase activity
NQ528_02770	COG0569	domain protein
NQ528_02775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NQ528_02790	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
NQ528_02795	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
NQ528_02800	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
NQ528_02805	COG2205	protein histidine kinase activity
NQ528_02825	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
NQ528_02835	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NQ528_02885	COG2217	Heavy metal translocating P-type atpase
NQ528_02890	COG1937	Protein conserved in bacteria
NQ528_02925	COG2972	Histidine kinase
NQ528_02930	COG2207	Transcriptional regulator
NQ528_02930	COG4753	response regulator
NQ528_02935	COG4211	Belongs to the binding-protein-dependent transport system permease family
NQ528_02950	COG0735	belongs to the Fur family
NQ528_02955	COG0803	Belongs to the bacterial solute-binding protein 9 family
NQ528_02960	COG1121	(ABC) transporter
NQ528_02965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NQ528_02970	COG0840	transmembrane signaling receptor activity
NQ528_02985	COG1321	iron dependent repressor
NQ528_03020	COG0534	Mate efflux family protein
NQ528_03025	COG1760	l-serine dehydratase
NQ528_03030	COG1760	l-serine dehydratase
NQ528_03045	COG4657	Part of a membrane complex involved in electron transport
NQ528_03050	COG4660	Part of a membrane complex involved in electron transport
NQ528_03070	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NQ528_03135	COG1070	Carbohydrate kinase
NQ528_03145	COG3623	hexulose-6-phosphate isomerase
NQ528_03150	COG1609	Transcriptional regulator
NQ528_03160	COG4149	molybdate abc transporter
NQ528_03165	COG1177	transmembrane transport
NQ528_03170	COG3842	ATPase activity
NQ528_03175	COG4806	L-rhamnose isomerase
NQ528_03185	COG1979	alcohol dehydrogenase
NQ528_03210	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NQ528_03210	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
NQ528_03215	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
NQ528_03220	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NQ528_03225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NQ528_03240	COG1414	Transcriptional regulator
NQ528_03245	COG1063	alcohol dehydrogenase
NQ528_03250	COG1028	Short-chain dehydrogenase reductase Sdr
NQ528_03260	COG3386	PFAM SMP-30 Gluconolaconase
NQ528_03265	COG4948	Mandelate Racemase Muconate Lactonizing
NQ528_03275	COG1129	ABC transporter
NQ528_03295	COG0457	Tetratricopeptide repeat
NQ528_03320	COG0745	RESPONSE REGULATOR receiver
NQ528_03330	COG0504	CTP synthase activity
NQ528_03335	COG3707	response regulator
NQ528_03355	COG0067	glutamate synthase
NQ528_03360	COG2502	aspartate--ammonia ligase
NQ528_03395	COG3409	Peptidoglycan-binding domain 1 protein
NQ528_03395	COG3757	hydrolase, family 25
NQ528_03415	COG4475	Protein of unknown function (DUF436)
NQ528_03435	COG0402	S-adenosylhomocysteine deaminase activity
NQ528_03440	COG2252	PERMEase
NQ528_03445	COG1529	Aldehyde oxidase and xanthine dehydrogenase
NQ528_03450	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
NQ528_03455	COG2080	2 iron, 2 sulfur cluster binding
NQ528_03465	COG1058	Belongs to the CinA family
NQ528_03465	COG1546	Belongs to the CinA family
NQ528_03480	COG2964	Protein conserved in bacteria
NQ528_03490	COG0402	S-adenosylhomocysteine deaminase activity
NQ528_03495	COG0493	'glutamate synthase
NQ528_03495	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
NQ528_03520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NQ528_03525	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NQ528_03530	COG0549	Belongs to the carbamate kinase family
NQ528_03550	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NQ528_03555	COG1921	L-seryl-tRNASec selenium transferase activity
NQ528_03580	COG3426	butyrate kinase activity
NQ528_03630	COG3964	amidohydrolase
NQ528_03670	COG3964	amidohydrolase
NQ528_03675	COG3711	transcriptional antiterminator
NQ528_03685	COG0732	type I restriction modification DNA specificity domain
NQ528_03705	COG2801	Transposase and inactivated derivatives
NQ528_03725	COG1396	sequence-specific DNA binding
NQ528_03755	COG2002	toxin-antitoxin pair type II binding
NQ528_03810	COG3409	Peptidoglycan-binding domain 1 protein
NQ528_03810	COG3773	Cell wall hydrolase
NQ528_03850	COG1475	DNA binding
NQ528_04065	COG3409	Peptidoglycan-binding domain 1 protein
NQ528_04065	COG3757	hydrolase, family 25
NQ528_04120	COG1373	ATPase (AAA superfamily
NQ528_04130	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NQ528_04160	COG2337	Toxic component of a toxin-antitoxin (TA) module
NQ528_04220	COG1690	Belongs to the RtcB family
NQ528_04505	COG0739	heme binding
NQ528_04640	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
NQ528_04650	COG2088	sporulation resulting in formation of a cellular spore
NQ528_04745	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NQ528_04750	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NQ528_04790	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
NQ528_04835	COG1846	Transcriptional regulator
NQ528_04855	COG1293	RNA-binding protein homologous to eukaryotic snRNP
NQ528_04860	COG0436	Aminotransferase
NQ528_04865	COG1522	sequence-specific DNA binding
NQ528_04870	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NQ528_04875	COG3830	Belongs to the UPF0237 family
NQ528_04880	COG2848	UPF0210 protein
NQ528_04915	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NQ528_04935	COG1346	cytolysis
NQ528_04940	COG1418	mRNA catabolic process
NQ528_04945	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NQ528_04955	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NQ528_04960	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
NQ528_04965	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
NQ528_04970	COG1649	PFAM Uncharacterised BCR, COG1649
NQ528_04970	COG0726	polysaccharide deacetylase
NQ528_04975	COG0513	Belongs to the DEAD box helicase family
NQ528_04980	COG0737	Belongs to the 5'-nucleotidase family
NQ528_05000	COG5564	TIM-barrel signal transduction protein
NQ528_05035	COG0322	excinuclease ABC activity
NQ528_05050	COG1649	PFAM Uncharacterised BCR, COG1649
NQ528_05065	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NQ528_05065	COG0493	'glutamate synthase
NQ528_05070	COG0739	heme binding
NQ528_05095	COG0662	Cupin 2, conserved barrel domain protein
NQ528_05100	COG0335	large ribosomal subunit rRNA binding
NQ528_05105	COG0681	Belongs to the peptidase S26 family
NQ528_05115	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
NQ528_05120	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NQ528_05125	COG0792	nuclease activity
NQ528_05145	COG0740	serine-type endopeptidase activity
NQ528_05150	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NQ528_05155	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
NQ528_05160	COG0218	Necessary for normal cell division and for the maintenance of normal septation
NQ528_05165	COG0019	diaminopimelate decarboxylase activity
NQ528_05170	COG4496	protein, YerC YecD
NQ528_05175	COG2226	methyltransferase
NQ528_05180	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
NQ528_05190	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
NQ528_05210	COG0628	permease
NQ528_05235	COG1132	(ABC) transporter
NQ528_05245	COG0745	RESPONSE REGULATOR receiver
NQ528_05265	COG0205	6-phosphofructokinase activity
NQ528_05300	COG2770	Histidine kinase
NQ528_05300	COG2208	phosphoserine phosphatase activity
NQ528_05305	COG2172	sigma factor antagonist activity
NQ528_05325	COG2274	protein secretion by the type I secretion system
NQ528_05330	COG2274	protein secretion by the type I secretion system
NQ528_05335	COG1366	Belongs to the anti-sigma-factor antagonist family
NQ528_05345	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NQ528_05350	COG1566	PFAM secretion protein HlyD family protein
NQ528_05355	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
NQ528_05360	COG0113	porphobilinogen synthase activity
NQ528_05370	COG0181	hydroxymethylbilane synthase activity
NQ528_05380	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
NQ528_05400	COG1420	regulation of RNA biosynthetic process
NQ528_05410	COG0443	Heat shock 70 kDa protein
NQ528_05415	COG0484	heat shock protein binding
NQ528_05420	COG2264	protein methyltransferase activity
NQ528_05425	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NQ528_05430	COG1876	peptidase activity
NQ528_05455	COG1126	abc transporter atp-binding protein
NQ528_05460	COG0765	amino acid transport
NQ528_05465	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQ528_05470	COG1472	Belongs to the glycosyl hydrolase 3 family
NQ528_05500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NQ528_05505	COG0366	Alpha amylase catalytic
NQ528_05510	COG1592	Rubrerythrin
NQ528_05520	COG1394	ATPase activity, coupled to movement of substances
NQ528_05525	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
NQ528_05530	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
NQ528_05550	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NQ528_05555	COG1269	ATP hydrolysis coupled proton transport
NQ528_05570	COG1136	(ABC) transporter
NQ528_05575	COG0577	efflux transmembrane transporter activity
NQ528_05585	COG0191	fructose-bisphosphate aldolase activity
NQ528_05590	COG1126	abc transporter atp-binding protein
NQ528_05595	COG0765	amino acid transport
NQ528_05605	COG1160	GTP binding
NQ528_05615	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
NQ528_05635	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NQ528_05640	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
NQ528_05665	COG1216	Glycosyl transferase, family 2
NQ528_05665	COG1442	glycosyl transferase family 8
NQ528_05670	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NQ528_05690	COG3959	Transketolase, thiamine diphosphate binding domain
NQ528_05695	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NQ528_05710	COG1216	Glycosyl transferase, family 2
NQ528_05710	COG1442	glycosyl transferase family 8
NQ528_05715	COG1442	glycosyl transferase family 8
NQ528_05715	COG1216	Glycosyl transferase, family 2
NQ528_05730	COG3955	Domain of unknown function (DUF1919)
NQ528_05735	COG0529	Catalyzes the synthesis of activated sulfate
NQ528_05755	COG0574	Belongs to the PEP-utilizing enzyme family
NQ528_05755	COG3848	Pyruvate phosphate dikinase
NQ528_05760	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NQ528_05765	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NQ528_05770	COG0613	PHP domain protein
NQ528_05780	COG2703	oxygen carrier activity
NQ528_05795	COG5002	protein histidine kinase activity
NQ528_05800	COG3212	peptidase
NQ528_05820	COG2373	Large extracellular alpha-helical protein
NQ528_05830	COG0457	Tetratricopeptide repeat
NQ528_05830	COG0463	Glycosyl transferase, family 2
NQ528_05845	COG1151	hydroxylamine reductase activity
NQ528_05855	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NQ528_05900	COG1013	pyruvate-flavodoxin oxidoreductase activity
NQ528_05905	COG0674	pyruvate-flavodoxin oxidoreductase activity
NQ528_05915	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NQ528_05920	COG1288	antiporter activity
NQ528_05925	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NQ528_06040	COG4213	ABC transporter substrate-binding protein
NQ528_06050	COG4214	carbohydrate transport
NQ528_06065	COG0303	'Molybdopterin
NQ528_06070	COG2226	methyltransferase
NQ528_06075	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NQ528_06100	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NQ528_06120	COG3843	relaxase mobilization nuclease domain protein
NQ528_06400	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NQ528_06405	COG1120	ATPase activity
NQ528_06410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NQ528_06415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NQ528_06425	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NQ528_06425	COG1522	sequence-specific DNA binding
NQ528_06445	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NQ528_06480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NQ528_06495	COG1396	sequence-specific DNA binding
NQ528_06515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NQ528_06520	COG1297	OPT oligopeptide transporter protein
NQ528_06535	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NQ528_06545	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
NQ528_06560	COG2310	stress, protein
NQ528_06575	COG1358	cellular component organization or biogenesis
NQ528_06590	COG2310	stress, protein
NQ528_06595	COG2310	stress, protein
NQ528_06600	COG2310	stress, protein
NQ528_06605	COG3853	Toxic anion resistance protein (TelA)
NQ528_06630	COG0326	Molecular chaperone. Has ATPase activity
NQ528_06635	COG0546	phosphoglycolate phosphatase activity
NQ528_06645	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NQ528_06670	COG0674	pyruvate-flavodoxin oxidoreductase activity
NQ528_06670	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
NQ528_06690	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
NQ528_06695	COG1074	ATP-dependent DNA helicase activity
NQ528_06705	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NQ528_06710	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NQ528_06715	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NQ528_06720	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NQ528_06725	COG0758	DNA mediated transformation
NQ528_06730	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NQ528_06735	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
NQ528_06740	COG0416	fatty acid biosynthetic process
NQ528_06760	COG0552	protein localization to endoplasmic reticulum
NQ528_06765	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NQ528_06770	COG1534	Rna-binding protein
NQ528_06775	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NQ528_06780	COG1713	HD superfamily hydrolase involved in NAD metabolism
NQ528_06785	COG0799	negative regulation of ribosome biogenesis
NQ528_06790	COG0495	leucyl-tRNA aminoacylation
NQ528_06795	COG0828	Belongs to the bacterial ribosomal protein bS21 family
NQ528_06805	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NQ528_06810	COG0006	proline dipeptidase activity
NQ528_06815	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NQ528_06825	COG1477	protein flavinylation
NQ528_06835	COG4656	Part of a membrane complex involved in electron transport
NQ528_06840	COG4658	electron transport chain
NQ528_06850	COG4660	Part of a membrane complex involved in electron transport
NQ528_06855	COG4657	Part of a membrane complex involved in electron transport
NQ528_06860	COG2878	Part of a membrane complex involved in electron transport
NQ528_06865	COG0564	pseudouridine synthase activity
NQ528_06870	COG2003	Belongs to the UPF0758 family
NQ528_06875	COG0583	DNA-binding transcription factor activity
NQ528_06880	COG4166	transmembrane transport
NQ528_06885	COG0601	transmembrane transport
NQ528_06895	COG0444	Belongs to the ABC transporter superfamily
NQ528_06900	COG4608	Belongs to the ABC transporter superfamily
NQ528_06910	COG0450	alkyl hydroperoxide reductase
NQ528_06920	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NQ528_06930	COG0583	DNA-binding transcription factor activity
NQ528_06935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NQ528_06940	COG1120	ATPase activity
NQ528_06945	COG0667	Aldo Keto reductase
NQ528_06950	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
NQ528_06960	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NQ528_06965	COG0436	Aminotransferase
NQ528_07025	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
NQ528_07030	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
NQ528_07045	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NQ528_07085	COG0179	Fumarylacetoacetate (FAA) hydrolase
NQ528_07090	COG1414	Transcriptional regulator
NQ528_07105	COG2721	sulfolactate sulfo-lyase activity
NQ528_07110	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NQ528_07130	COG2081	HI0933 family
NQ528_07135	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NQ528_07145	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NQ528_07145	COG0539	negative regulation of cytoplasmic translation
NQ528_07155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NQ528_07160	COG1490	D-aminoacyl-tRNA deacylase activity
NQ528_07165	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
NQ528_07170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NQ528_07180	COG0534	Mate efflux family protein
NQ528_07185	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NQ528_07190	COG2244	polysaccharide biosynthetic process
NQ528_07195	COG3956	TIGRFAM MazG family protein
NQ528_07205	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
NQ528_07230	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
NQ528_07240	COG4608	Belongs to the ABC transporter superfamily
NQ528_07245	COG0747	negative chemotaxis
NQ528_07250	COG0601	transmembrane transport
NQ528_07255	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NQ528_07265	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
NQ528_07275	COG1609	Transcriptional regulator
NQ528_07280	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
NQ528_07330	COG0328	RNA-DNA hybrid ribonuclease activity
NQ528_07430	COG0357	Ribosomal RNA small subunit methyltransferase G
NQ528_07450	COG0556	nucleotide-excision repair
NQ528_07480	COG1414	Transcriptional regulator
NQ528_07495	COG1063	alcohol dehydrogenase
NQ528_07510	COG0471	metal ion transport
NQ528_07520	COG3958	Transketolase
NQ528_07525	COG1012	belongs to the aldehyde dehydrogenase family
NQ528_07555	COG3293	Transposase
NQ528_07580	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NQ528_07585	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NQ528_07590	COG1414	Transcriptional regulator
NQ528_07660	COG0582	viral genome integration into host DNA
NQ528_07665	COG0556	nucleotide-excision repair
NQ528_07675	COG1773	rubredoxin
NQ528_07680	COG0426	domain, Protein
NQ528_07690	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NQ528_07700	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
NQ528_07705	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
NQ528_07710	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NQ528_07715	COG1923	regulation of RNA biosynthetic process
NQ528_07725	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NQ528_07730	COG1799	cell septum assembly
NQ528_07735	COG2302	S4 RNA-binding domain
NQ528_07745	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NQ528_07750	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
NQ528_07755	COG0564	pseudouridine synthase activity
NQ528_07765	COG0475	glutathione-regulated potassium exporter activity
NQ528_07785	COG0606	chelatase, subunit chli
NQ528_07795	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NQ528_07805	COG0254	rRNA binding
NQ528_07810	COG0564	pseudouridine synthase activity
NQ528_07815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQ528_07820	COG0765	amino acid transport
NQ528_07830	COG1692	metallophosphoesterase
NQ528_07850	COG1461	Dihydroxyacetone kinase
NQ528_07865	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NQ528_07870	COG0537	adenosine 5'-monophosphoramidase activity
NQ528_07880	COG0017	Asparaginyl-tRNA synthetase
NQ528_07885	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQ528_07890	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NQ528_07895	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NQ528_07910	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NQ528_07940	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
NQ528_07945	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
NQ528_07955	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NQ528_07960	COG1660	Displays ATPase and GTPase activities
NQ528_07965	COG1481	regulation of sporulation
NQ528_07985	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NQ528_07990	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NQ528_08000	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NQ528_08005	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
NQ528_08015	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
NQ528_08025	COG0116	Belongs to the methyltransferase superfamily
NQ528_08035	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NQ528_08040	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NQ528_08060	COG1098	S1 RNA binding domain
NQ528_08065	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
NQ528_08075	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NQ528_08165	COG1396	sequence-specific DNA binding
NQ528_08225	COG0629	single-stranded DNA binding
NQ528_08235	COG1484	DNA-dependent DNA replication
NQ528_08375	COG3655	Transcriptional regulator
NQ528_08445	COG3409	Peptidoglycan-binding domain 1 protein
NQ528_08445	COG3757	hydrolase, family 25
NQ528_08485	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NQ528_08490	COG0632	four-way junction helicase activity
NQ528_08495	COG2255	four-way junction helicase activity
NQ528_08500	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NQ528_08505	COG0116	Belongs to the methyltransferase superfamily
NQ528_08505	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
NQ528_08510	COG1122	ATPase activity
NQ528_08520	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
NQ528_08545	COG0542	response to heat
NQ528_08550	COG1196	nuclear chromosome segregation
NQ528_08550	COG0741	lytic transglycosylase activity
NQ528_08550	COG0739	heme binding
NQ528_08555	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
NQ528_08565	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NQ528_08575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NQ528_08580	COG1028	Short-chain dehydrogenase reductase Sdr
NQ528_08635	COG1595	DNA-templated transcription, initiation
NQ528_08645	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
NQ528_08645	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
NQ528_08650	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NQ528_08655	COG0765	amino acid transport
NQ528_08660	COG1126	abc transporter atp-binding protein
NQ528_08685	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NQ528_08690	COG0733	neurotransmitter:sodium symporter activity
NQ528_08700	COG0052	Belongs to the universal ribosomal protein uS2 family
NQ528_08705	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NQ528_08720	COG3859	Proton-coupled thiamine transporter YuaJ
NQ528_08730	COG0437	4 iron, 4 sulfur cluster binding
NQ528_08745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NQ528_08750	COG1757	Na H antiporter
NQ528_08755	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NQ528_08765	COG0233	cytoplasmic translational termination
NQ528_08770	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NQ528_08775	COG4589	Belongs to the CDS family
NQ528_08785	COG0750	zinc metalloprotease
NQ528_08790	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NQ528_08800	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
NQ528_08805	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
NQ528_08810	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
NQ528_08815	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NQ528_08820	COG0131	Imidazoleglycerol-phosphate dehydratase
NQ528_08835	COG0107	imidazoleglycerol-phosphate synthase activity
NQ528_08840	COG0140	phosphoribosyl-ATP diphosphatase activity
NQ528_08840	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
NQ528_08850	COG0527	aspartate kinase activity
NQ528_08855	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
NQ528_08860	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NQ528_08870	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
NQ528_08875	COG0343	queuine tRNA-ribosyltransferase activity
NQ528_08880	COG1862	Preprotein translocase
NQ528_08905	COG4974	Belongs to the 'phage' integrase family
NQ528_08925	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NQ528_08930	COG0860	N-Acetylmuramoyl-L-alanine amidase
NQ528_08935	COG3842	ATPase activity
NQ528_08940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NQ528_08945	COG0395	ABC-type sugar transport system, permease component
NQ528_08950	COG1175	transmembrane transport
NQ528_08960	COG1737	Transcriptional regulator
NQ528_08970	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NQ528_08995	COG1592	Rubrerythrin
NQ528_08995	COG1773	rubredoxin
NQ528_09000	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NQ528_09015	COG1335	isochorismatase
NQ528_09020	COG1457	Belongs to the purine-cytosine permease (2.A.39) family
NQ528_09030	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NQ528_09035	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NQ528_09040	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NQ528_09045	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NQ528_09050	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NQ528_09055	COG0612	Peptidase, M16
NQ528_09065	COG3459	Glycosyltransferase 36 associated
NQ528_09075	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NQ528_09080	COG0747	negative chemotaxis
NQ528_09085	COG0601	transmembrane transport
NQ528_09090	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NQ528_09095	COG0444	Belongs to the ABC transporter superfamily
NQ528_09110	COG1053	succinate dehydrogenase
NQ528_09130	COG1492	cobalamin metabolic process
NQ528_09135	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
NQ528_09140	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
NQ528_09155	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
NQ528_09165	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
NQ528_09170	COG1797	cobyrinic acid a,c-diamide synthase activity
NQ528_09200	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
NQ528_09210	COG1725	Transcriptional regulator
NQ528_09215	COG1131	(ABC) transporter
NQ528_09225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NQ528_09230	COG1191	sigma factor activity
NQ528_09245	COG1191	sigma factor activity
NQ528_09270	COG1691	(AIR) carboxylase
NQ528_09285	COG0066	3-isopropylmalate dehydratase activity
NQ528_09290	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NQ528_09295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NQ528_09300	COG4684	Psort location CytoplasmicMembrane, score
NQ528_09305	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NQ528_09310	COG0497	DNA recombination
NQ528_09315	COG1438	arginine binding
NQ528_09320	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NQ528_09325	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
NQ528_09330	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NQ528_09335	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
NQ528_09340	COG0142	geranyltranstransferase activity
NQ528_09345	COG1722	exodeoxyribonuclease VII activity
NQ528_09350	COG1570	exodeoxyribonuclease VII activity
NQ528_09355	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NQ528_09360	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NQ528_09405	COG3854	ATPases associated with a variety of cellular activities
NQ528_09420	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
NQ528_09440	COG0542	response to heat
NQ528_09450	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NQ528_09455	COG1177	transmembrane transport
NQ528_09460	COG1176	ABC-type spermidine putrescine transport system, permease component I
NQ528_09465	COG3842	ATPase activity
NQ528_09480	COG3623	hexulose-6-phosphate isomerase
NQ528_09505	COG0559	Belongs to the binding-protein-dependent transport system permease family
NQ528_09515	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
NQ528_09520	COG0438	transferase activity, transferring glycosyl groups
NQ528_09530	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NQ528_09545	COG0436	Aminotransferase
NQ528_09550	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NQ528_09575	COG0281	malic enzyme
NQ528_09580	COG0613	PHP domain protein
NQ528_09605	COG0318	PFAM AMP-dependent synthetase and ligase
NQ528_09620	COG0492	ferredoxin-NADP+ reductase activity
NQ528_09625	COG0287	Prephenate dehydrogenase
NQ528_09630	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
NQ528_09635	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NQ528_09640	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NQ528_09650	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NQ528_09665	COG1028	Short-chain dehydrogenase reductase Sdr
NQ528_09705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NQ528_09710	COG1609	Transcriptional regulator
NQ528_09715	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NQ528_09715	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NQ528_09725	COG0083	homoserine kinase activity
NQ528_09730	COG0460	homoserine dehydrogenase
NQ528_09735	COG4492	Belongs to the UPF0735 family
NQ528_09760	COG3585	molybdate ion transport
NQ528_09780	COG0517	IMP dehydrogenase activity
NQ528_09780	COG0516	GMP reductase activity
NQ528_09795	COG0667	Aldo Keto reductase
NQ528_09810	COG0745	RESPONSE REGULATOR receiver
NQ528_09815	COG0750	zinc metalloprotease
NQ528_09835	COG0697	spore germination
NQ528_09840	COG2323	membrane
NQ528_09855	COG0372	Belongs to the citrate synthase family
NQ528_09890	COG0280	phosphate acetyltransferase
NQ528_09895	COG3426	butyrate kinase activity
NQ528_09900	COG1013	pyruvate-flavodoxin oxidoreductase activity
NQ528_09905	COG0674	pyruvate-flavodoxin oxidoreductase activity
NQ528_09920	COG0039	L-malate dehydrogenase activity
NQ528_09925	COG1473	amidohydrolase
NQ528_09930	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NQ528_09945	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
NQ528_09945	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
NQ528_09965	COG0733	neurotransmitter:sodium symporter activity
NQ528_09975	COG2818	Glycosylase
NQ528_09980	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NQ528_10000	COG0577	efflux transmembrane transporter activity
NQ528_10010	COG0534	Mate efflux family protein
NQ528_10035	COG1070	Carbohydrate kinase
NQ528_10040	COG4214	carbohydrate transport
NQ528_10045	COG1129	ABC transporter
NQ528_10050	COG4213	ABC transporter substrate-binding protein
NQ528_10065	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
NQ528_10070	COG0456	acetyltransferase
NQ528_10090	COG1011	Hydrolase
NQ528_10095	COG1115	amino acid carrier protein
NQ528_10100	COG0077	Prephenate dehydratase
NQ528_10100	COG1605	Chorismate mutase
NQ528_10105	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NQ528_10120	COG1671	Belongs to the UPF0178 family
NQ528_10130	COG1595	DNA-templated transcription, initiation
NQ528_10140	COG0151	Belongs to the GarS family
NQ528_10145	COG0138	bifunctional purine biosynthesis protein purh
NQ528_10160	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NQ528_10165	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NQ528_10175	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NQ528_10190	COG1132	(ABC) transporter
NQ528_10205	COG3681	Belongs to the UPF0597 family
NQ528_10210	COG3829	transcription factor binding
NQ528_10225	COG1215	transferase activity, transferring glycosyl groups
NQ528_10245	COG2033	superoxide reductase activity
NQ528_10280	COG0395	ABC-type sugar transport system, permease component
NQ528_10285	COG1175	transmembrane transport
NQ528_10300	COG5002	protein histidine kinase activity
NQ528_10320	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NQ528_10335	COG1686	Belongs to the peptidase S11 family
NQ528_10340	COG2088	sporulation resulting in formation of a cellular spore
NQ528_10345	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NQ528_10360	COG1794	racemase activity, acting on amino acids and derivatives
NQ528_10375	COG0252	asparaginase activity
NQ528_10390	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
NQ528_10395	COG2086	electron transfer activity
NQ528_10400	COG1960	acyl-CoA dehydrogenase activity
NQ528_10405	COG1250	3-hydroxyacyl-CoA dehydrogenase
NQ528_10410	COG1024	Enoyl-CoA hydratase
NQ528_10415	COG0183	Belongs to the thiolase family
NQ528_10430	COG0456	acetyltransferase
NQ528_10430	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NQ528_10435	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
NQ528_10445	COG5002	protein histidine kinase activity
NQ528_10465	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NQ528_10475	COG0360	Binds together with S18 to 16S ribosomal RNA
NQ528_10485	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NQ528_10490	COG3608	succinylglutamate desuccinylase aspartoacylase
NQ528_10490	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
NQ528_10495	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NQ528_10500	COG0583	DNA-binding transcription factor activity
NQ528_10525	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NQ528_10540	COG1917	Cupin 2, conserved barrel domain protein
NQ528_10540	COG4977	sequence-specific DNA binding
NQ528_10555	COG3681	Belongs to the UPF0597 family
NQ528_10565	COG0559	Belongs to the binding-protein-dependent transport system permease family
NQ528_10585	COG2376	Dihydroxyacetone kinase
NQ528_10590	COG1461	Dihydroxyacetone kinase
NQ528_10595	COG3829	transcription factor binding
NQ528_10605	COG0784	Response regulator, receiver
NQ528_10605	COG0835	chemotaxis
NQ528_10625	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
NQ528_10635	COG1254	Belongs to the acylphosphatase family
NQ528_10650	COG2226	methyltransferase
NQ528_10655	COG0561	phosphatase activity
NQ528_10680	COG1137	ATPase activity
NQ528_10685	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
NQ528_10710	COG0534	Mate efflux family protein
NQ528_10745	COG0154	amidase activity
NQ528_10750	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NQ528_10755	COG2508	Transcriptional regulator
NQ528_10765	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
NQ528_10775	COG1304	FMN binding
NQ528_10790	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NQ528_10795	COG5002	protein histidine kinase activity
NQ528_10800	COG0745	RESPONSE REGULATOR receiver
NQ528_10810	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
NQ528_10815	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NQ528_10825	COG0840	transmembrane signaling receptor activity
NQ528_10835	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
NQ528_10840	COG1776	CheC inhibitor of MCP methylation
NQ528_10845	COG4786	Flagellar basal body rod
NQ528_10850	COG4786	Flagellar basal body rod
NQ528_10860	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
NQ528_10875	COG1987	bacterial-type flagellum assembly
NQ528_10890	COG2201	protein-glutamate methylesterase activity
NQ528_10895	COG1776	CheC inhibitor of MCP methylation
NQ528_10895	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NQ528_10900	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NQ528_10905	COG1360	Flagellar Motor Protein
NQ528_10915	COG1582	Flagellar protein (FlbD)
NQ528_10930	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
NQ528_10945	COG1157	protein secretion by the type III secretion system
NQ528_10955	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
NQ528_10965	COG1677	Flagellar hook-basal body complex protein FliE
NQ528_10980	COG1815	bacterial-type flagellum-dependent cell motility
NQ528_11000	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
NQ528_11015	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
NQ528_11020	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
NQ528_11030	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NQ528_11050	COG1192	Involved in chromosome partitioning
NQ528_11075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NQ528_11075	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
NQ528_11085	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
NQ528_11110	COG0643	Histidine kinase
NQ528_11110	COG2198	Histidine kinase
NQ528_11115	COG0835	chemotaxis
NQ528_11125	COG2201	protein-glutamate methylesterase activity
NQ528_11130	COG0561	phosphatase activity
NQ528_11135	COG1690	Belongs to the RtcB family
NQ528_11145	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NQ528_11155	COG1609	Transcriptional regulator
NQ528_11165	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
NQ528_11170	COG3639	organic phosphonate transmembrane transporter activity
NQ528_11180	COG0737	Belongs to the 5'-nucleotidase family
NQ528_11190	COG0445	tRNA wobble uridine modification
NQ528_11195	COG0726	polysaccharide deacetylase
NQ528_11225	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
NQ528_11225	COG0493	'glutamate synthase
NQ528_11230	COG0243	molybdopterin cofactor binding
NQ528_11235	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
NQ528_11255	COG1079	Belongs to the binding-protein-dependent transport system permease family
NQ528_11260	COG4603	Belongs to the binding-protein-dependent transport system permease family
NQ528_11265	COG3845	ABC transporter
NQ528_11275	COG0295	cytidine deaminase activity
NQ528_11285	COG1328	CTP reductase activity
NQ528_11290	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
NQ528_11295	COG2337	Toxic component of a toxin-antitoxin (TA) module
NQ528_11305	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NQ528_11305	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NQ528_11315	COG0459	protein refolding
NQ528_11320	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NQ528_11325	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NQ528_11330	COG4720	Psort location CytoplasmicMembrane, score
NQ528_11365	COG1879	ABC-type sugar transport system periplasmic component
NQ528_11370	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ528_11375	COG1129	ABC transporter
NQ528_11390	COG1349	DNA-binding transcription factor activity
NQ528_11400	COG0303	'Molybdopterin
NQ528_11405	COG1811	Na channel or pump
NQ528_11415	COG1528	Iron-storage protein
NQ528_11420	COG0393	Putative heavy-metal-binding
NQ528_11425	COG1396	sequence-specific DNA binding
NQ528_11460	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
NQ528_11470	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NQ528_11475	COG0351	phosphomethylpyrimidine kinase
NQ528_11475	COG0352	thiamine-phosphate diphosphorylase activity
NQ528_11500	COG1033	growth of symbiont in host cell
NQ528_11500	COG2409	Drug exporters of the RND superfamily
NQ528_11520	COG2155	Conserved Protein
NQ528_11530	COG0519	Catalyzes the synthesis of GMP from XMP
NQ528_11550	COG0310	cobalt ion transport
NQ528_11570	COG2172	sigma factor antagonist activity
NQ528_11585	COG0525	valine-tRNA ligase activity
NQ528_11590	COG0741	lytic transglycosylase activity
NQ528_11590	COG0739	heme binding
NQ528_11590	COG1196	nuclear chromosome segregation
NQ528_11595	COG5012	cobalamin binding
NQ528_11600	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
NQ528_11715	COG3039	Transposase
NQ528_11730	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ528_11740	COG0346	lactoylglutathione lyase activity
NQ528_11790	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NQ528_11795	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
NQ528_11835	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NQ528_11840	COG1396	sequence-specific DNA binding
NQ528_11845	COG1970	mechanosensitive ion channel activity
NQ528_11855	COG2873	o-acetylhomoserine
NQ528_11865	COG1959	2 iron, 2 sulfur cluster binding
NQ528_11875	COG0598	Magnesium transport protein CorA
NQ528_11895	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NQ528_11900	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
NQ528_11905	COG0346	lactoylglutathione lyase activity
NQ528_11920	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ528_11930	COG1609	Transcriptional regulator
NQ528_11935	COG0673	inositol 2-dehydrogenase activity
NQ528_11940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NQ528_11945	COG1260	myo-inositol-1-phosphate synthase
NQ528_12040	COG2176	DNA-directed DNA polymerase activity
NQ528_12085	COG1484	DNA-dependent DNA replication
NQ528_12180	COG0740	serine-type endopeptidase activity
NQ528_12300	COG3409	Peptidoglycan-binding domain 1 protein
NQ528_12300	COG3757	hydrolase, family 25
NQ528_12320	COG2246	polysaccharide biosynthetic process
NQ528_12325	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NQ528_12330	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
NQ528_12335	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NQ528_12350	COG0768	penicillin binding
NQ528_12355	COG1396	sequence-specific DNA binding
NQ528_12370	COG1210	Utp--glucose-1-phosphate uridylyltransferase
NQ528_12425	COG1396	sequence-specific DNA binding
NQ528_12445	COG3142	Participates in the control of copper homeostasis
NQ528_12460	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
NQ528_12465	COG0072	phenylalanine-tRNA ligase activity
NQ528_12465	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NQ528_12475	COG1028	Short-chain dehydrogenase reductase Sdr
NQ528_12480	COG1396	sequence-specific DNA binding
NQ528_12485	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NQ528_12495	COG1193	negative regulation of DNA recombination
NQ528_12500	COG1381	Involved in DNA repair and RecF pathway recombination
NQ528_12510	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NQ528_12515	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
NQ528_12520	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NQ528_12550	COG0860	N-Acetylmuramoyl-L-alanine amidase
NQ528_12555	COG0733	neurotransmitter:sodium symporter activity
NQ528_12560	COG3033	Beta-eliminating lyase
NQ528_12570	COG2964	Protein conserved in bacteria
NQ528_12580	COG2364	Membrane
NQ528_12585	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NQ528_12610	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
NQ528_12645	COG0646	methionine synthase
NQ528_12645	COG1410	methionine synthase
NQ528_12650	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NQ528_12650	COG0646	methionine synthase
NQ528_12660	COG1132	(ABC) transporter
NQ528_12665	COG1132	(ABC) transporter
NQ528_12675	COG0482	sulfurtransferase activity
NQ528_12690	COG1105	Belongs to the carbohydrate kinase PfkB family
NQ528_12705	COG0037	tRNA processing
NQ528_12710	COG0305	Participates in initiation and elongation during chromosome replication
NQ528_12715	COG0359	binds to the 23S rRNA
NQ528_12720	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
NQ528_12745	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NQ528_12750	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
NQ528_12755	COG0328	RNA-DNA hybrid ribonuclease activity
NQ528_12790	COG0110	maltose O-acetyltransferase activity
NQ528_12810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NQ528_12815	COG0358	DNA primase activity
NQ528_12820	COG0232	Belongs to the dGTPase family. Type 2 subfamily
NQ528_12825	COG1739	Uncharacterized protein family UPF0029
NQ528_12830	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NQ528_12860	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NQ528_12870	COG1802	Transcriptional regulator
NQ528_12880	COG2972	Histidine kinase
NQ528_12885	COG0683	leucine binding
NQ528_12905	COG0410	ABC transporter
NQ528_12925	COG0187	DNA topoisomerase II activity
NQ528_12930	COG1247	-acetyltransferase
NQ528_12940	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NQ528_12950	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NQ528_12955	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
NQ528_12960	COG0772	Belongs to the SEDS family
NQ528_12965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NQ528_12970	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NQ528_12980	COG0768	penicillin binding
NQ528_12995	COG2001	Belongs to the MraZ family
NQ528_13000	COG0217	transcriptional regulatory protein
NQ528_13005	COG0826	peptidase U32
NQ528_13010	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
NQ528_13030	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NQ528_13035	COG0693	protein deglycase activity
NQ528_13050	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
NQ528_13075	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
NQ528_13085	COG1085	galactose-1-phosphate uridylyltransferase
NQ528_13090	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NQ528_13095	COG2207	Transcriptional regulator
NQ528_13100	COG0668	transmembrane transport
NQ528_13130	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NQ528_13145	COG0860	N-Acetylmuramoyl-L-alanine amidase
NQ528_13150	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
NQ528_13155	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NQ528_13160	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NQ528_13165	COG0049	tRNA binding
NQ528_13170	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NQ528_13175	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NQ528_13180	COG0085	RNA polymerase activity
NQ528_13185	COG2431	L-lysine efflux transmembrane transporter activity
NQ528_13195	COG1362	aminopeptidase activity
NQ528_13200	COG0741	lytic transglycosylase activity
NQ528_13200	COG1196	nuclear chromosome segregation
NQ528_13200	COG0739	heme binding
NQ528_13205	COG0237	dephospho-CoA kinase activity
NQ528_13210	COG0009	L-threonylcarbamoyladenylate synthase
NQ528_13215	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NQ528_13220	COG4481	Protein conserved in bacteria
NQ528_13225	COG1185	polyribonucleotide nucleotidyltransferase activity
NQ528_13235	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
NQ528_13240	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NQ528_13255	COG1720	tRNA m6t6A37 methyltransferase activity
NQ528_13280	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ528_13285	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ528_13315	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NQ528_13380	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
NQ528_13415	COG0066	3-isopropylmalate dehydratase activity
NQ528_13420	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
NQ528_13470	COG0583	DNA-binding transcription factor activity
NQ528_13485	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NQ528_13490	COG1323	Belongs to the UPF0348 family
NQ528_13510	COG1131	(ABC) transporter
NQ528_13775	COG1131	(ABC) transporter
NQ528_13795	COG0745	RESPONSE REGULATOR receiver
NQ528_13805	COG0745	RESPONSE REGULATOR receiver
NQ528_13815	COG1136	(ABC) transporter
NQ528_13815	COG0577	efflux transmembrane transporter activity
NQ528_13820	COG0577	efflux transmembrane transporter activity
NQ528_13825	COG1136	(ABC) transporter
NQ528_13825	COG0577	efflux transmembrane transporter activity
NQ528_13835	COG0577	efflux transmembrane transporter activity
NQ528_13855	COG0745	RESPONSE REGULATOR receiver
NQ528_13870	COG4474	Belongs to the UPF0398 family
NQ528_13915	COG2205	protein histidine kinase activity
NQ528_13920	COG0745	RESPONSE REGULATOR receiver
NQ528_13945	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NQ528_13990	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NQ528_13995	COG5377	YqaJ viral recombinase family
NQ528_14010	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NQ528_14015	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NQ528_14020	COG0793	Belongs to the peptidase S41A family
NQ528_14025	COG0739	heme binding
NQ528_14030	COG2177	Part of the ABC transporter FtsEX involved in
NQ528_14035	COG2884	Cell division ATP-binding protein ftsE
NQ528_14040	COG3835	regulator
NQ528_14045	COG1187	pseudouridine synthase activity
NQ528_14060	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NQ528_14070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NQ528_14100	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NQ528_14105	COG0180	Tryptophanyl-tRNA synthetase
NQ528_14110	COG0700	Nucleoside recognition
NQ528_14115	COG2715	membrane protein required for spore maturation
NQ528_14120	COG2002	toxin-antitoxin pair type II binding
NQ528_14130	COG0473	3-isopropylmalate dehydrogenase activity
NQ528_14135	COG0406	alpha-ribazole phosphatase activity
NQ528_14150	COG0745	RESPONSE REGULATOR receiver
NQ528_14155	COG5002	protein histidine kinase activity
NQ528_14160	COG3872	metal-dependent enzyme
NQ528_14165	COG2890	protein-(glutamine-N5) methyltransferase activity
NQ528_14170	COG0297	glycogen (starch) synthase activity
NQ528_14175	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NQ528_14180	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
NQ528_14185	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NQ528_14195	COG5002	protein histidine kinase activity
NQ528_14205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NQ528_14205	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NQ528_14210	COG0084	hydrolase, TatD family'
NQ528_14225	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
NQ528_14245	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NQ528_14260	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
NQ528_14285	COG2002	toxin-antitoxin pair type II binding
NQ528_14290	COG3804	dihydrodipicolinate reductase
NQ528_14300	COG1396	sequence-specific DNA binding
NQ528_14305	COG1396	sequence-specific DNA binding
NQ528_14310	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
NQ528_14315	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
NQ528_14340	COG4656	Part of a membrane complex involved in electron transport
NQ528_14355	COG1454	alcohol dehydrogenase
NQ528_14375	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NQ528_14385	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ528_14390	COG1129	ABC transporter
NQ528_14400	COG2376	Dihydroxyacetone kinase
NQ528_14445	COG0426	domain, Protein
NQ528_14450	COG1960	acyl-CoA dehydrogenase activity
NQ528_14485	COG1222	aaa ATPase
NQ528_14660	COG2226	methyltransferase
NQ528_14665	COG1191	sigma factor activity
NQ528_14695	COG1484	DNA-dependent DNA replication
NQ528_14720	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
NQ528_14730	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ528_14735	COG1129	ABC transporter
NQ528_14750	COG1609	Transcriptional regulator
NQ528_14890	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
NQ528_14900	COG2337	Toxic component of a toxin-antitoxin (TA) module
NQ528_14960	COG1690	Belongs to the RtcB family
NQ528_14985	COG3196	Protein conserved in bacteria
NQ528_15235	COG0739	heme binding
NQ528_15370	COG2088	sporulation resulting in formation of a cellular spore
NQ528_15475	COG3118	belongs to the thioredoxin family
NQ528_15495	COG4149	molybdate abc transporter
NQ528_15500	COG0725	ABC transporter, periplasmic molybdate-binding protein
NQ528_15540	COG1162	GTPase activity
NQ528_15545	COG2815	serine threonine protein kinase
NQ528_15545	COG0515	serine threonine protein kinase
NQ528_15555	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NQ528_15560	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
NQ528_15560	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NQ528_15565	COG2738	Putative neutral zinc metallopeptidase
NQ528_15570	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NQ528_15580	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NQ528_15590	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
NQ528_15600	COG0194	GDP metabolic process
NQ528_15605	COG2052	Domain of unknown function (DUF370)
NQ528_15610	COG1561	YicC-like family, N-terminal region
NQ528_15620	COG4770	biotin carboxylase activity
NQ528_15625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NQ528_15635	COG1187	pseudouridine synthase activity
NQ528_15640	COG1686	Belongs to the peptidase S11 family
NQ528_15645	COG3874	Sporulation protein YtfJ
NQ528_15655	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NQ528_15665	COG1994	Peptidase M50
NQ528_15670	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NQ528_15680	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
NQ528_15685	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
NQ528_15690	COG1160	GTP binding
NQ528_15700	COG0333	Belongs to the bacterial ribosomal protein bL32 family
NQ528_15715	COG0166	Belongs to the GPI family
NQ528_15720	COG1686	Belongs to the peptidase S11 family
NQ528_15735	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NQ528_15740	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NQ528_15755	COG2201	protein-glutamate methylesterase activity
NQ528_15765	COG2873	o-acetylhomoserine
NQ528_15770	COG1686	Belongs to the peptidase S11 family
NQ528_15780	COG1309	transcriptional regulator
NQ528_15785	COG1132	(ABC) transporter
NQ528_15790	COG1132	(ABC) transporter
NQ528_15795	COG0222	ribosome binding
NQ528_15800	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NQ528_15805	COG0081	regulation of translation
NQ528_15810	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NQ528_15815	COG0250	Participates in transcription elongation, termination and antitermination
NQ528_15820	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NQ528_15825	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NQ528_15835	COG1181	Belongs to the D-alanine--D-alanine ligase family
NQ528_15840	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NQ528_15850	COG0018	arginyl-trna synthetase
NQ528_15855	COG0646	methionine synthase
NQ528_15855	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NQ528_15860	COG1773	rubredoxin
NQ528_15860	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
NQ528_15865	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NQ528_15875	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
NQ528_15880	COG0193	aminoacyl-tRNA hydrolase activity
NQ528_15890	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NQ528_15895	COG0574	Belongs to the PEP-utilizing enzyme family
NQ528_15895	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NQ528_15905	COG0772	Belongs to the SEDS family
NQ528_15915	COG0802	atpase or kinase
NQ528_15920	COG1214	PFAM Peptidase M22, glycoprotease
NQ528_15925	COG0698	ribose 5-phosphate isomerase
NQ528_15930	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NQ528_15960	COG1058	Belongs to the CinA family
NQ528_15960	COG1546	Belongs to the CinA family
NQ528_15970	COG0301	tRNA thio-modification
NQ528_15975	COG1104	cysteine desulfurase activity
NQ528_15980	COG2959	enzyme of heme biosynthesis
NQ528_15990	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NQ528_16015	COG1132	(ABC) transporter
NQ528_16020	COG1132	(ABC) transporter
NQ528_16030	COG1079	Belongs to the binding-protein-dependent transport system permease family
NQ528_16035	COG4603	Belongs to the binding-protein-dependent transport system permease family
NQ528_16040	COG3845	ABC transporter
NQ528_16045	COG1744	ABC transporter substrate-binding protein PnrA-like
NQ528_16050	COG1609	Transcriptional regulator
NQ528_16060	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ528_16065	COG1129	ABC transporter
NQ528_16075	COG2972	Histidine kinase
NQ528_16080	COG4753	response regulator
NQ528_16080	COG2207	Transcriptional regulator
NQ528_16085	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
NQ528_16090	COG1940	carbohydrate kinase activity
NQ528_16100	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NQ528_16100	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NQ528_16110	COG1940	carbohydrate kinase activity
NQ528_16120	COG1482	cell wall glycoprotein biosynthetic process
NQ528_16130	COG2188	Transcriptional regulator
NQ528_16135	COG1744	ABC transporter substrate-binding protein PnrA-like
NQ528_16145	COG4603	Belongs to the binding-protein-dependent transport system permease family
NQ528_16150	COG3845	ABC transporter
NQ528_16160	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
NQ528_16165	COG1328	CTP reductase activity
NQ528_16170	COG0840	transmembrane signaling receptor activity
NQ528_16175	COG1737	Transcriptional regulator
NQ528_16180	COG0698	ribose 5-phosphate isomerase
NQ528_16185	COG0149	triose-phosphate isomerase activity
NQ528_16210	COG2376	Dihydroxyacetone kinase
NQ528_16235	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ528_16240	COG1129	ABC transporter
NQ528_16265	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NQ528_16270	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NQ528_16280	COG1396	sequence-specific DNA binding
NQ528_16295	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NQ528_16300	COG0124	histidyl-tRNA synthetase
NQ528_16305	COG1803	Methylglyoxal synthase
NQ528_16310	COG2894	cell division
NQ528_16315	COG0768	penicillin binding
NQ528_16330	COG1077	Cell shape determining protein MreB Mrl
NQ528_16335	COG0424	maF-like protein
NQ528_16350	COG0826	peptidase U32
NQ528_16355	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
NQ528_16360	COG0058	SHG alpha-glucan phosphorylase activity
NQ528_16365	COG0366	Alpha amylase catalytic
NQ528_16365	COG3103	Sh3 type 3 domain protein
NQ528_16370	COG0577	efflux transmembrane transporter activity
NQ528_16370	COG1136	(ABC) transporter
NQ528_16400	COG1328	CTP reductase activity
NQ528_16410	COG0488	(ABC) transporter
NQ528_16425	COG0583	DNA-binding transcription factor activity
NQ528_16430	COG1063	alcohol dehydrogenase
NQ528_16435	COG0069	glutamate synthase activity
NQ528_16445	COG4974	Belongs to the 'phage' integrase family
NQ528_16450	COG3033	Beta-eliminating lyase
NQ528_16455	COG0733	neurotransmitter:sodium symporter activity
NQ528_16480	COG0534	Mate efflux family protein
NQ528_16485	COG3608	succinylglutamate desuccinylase aspartoacylase
NQ528_16495	COG0444	Belongs to the ABC transporter superfamily
NQ528_16500	COG2188	Transcriptional regulator
NQ528_16510	COG1172	Belongs to the binding-protein-dependent transport system permease family
NQ528_16515	COG1129	ABC transporter
NQ528_16520	COG1879	ABC-type sugar transport system periplasmic component
NQ528_16555	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NQ528_16580	COG2188	Transcriptional regulator
NQ528_16590	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
NQ528_16610	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NQ528_16625	COG0481	GTPase activity
NQ528_16635	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NQ528_16640	COG3906	Belongs to the UPF0473 family
NQ528_16660	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NQ528_16680	COG0534	Mate efflux family protein
NQ528_16730	COG3299	homolog of phage Mu protein gp47
NQ528_16735	COG3628	GPW Gp25 family protein
NQ528_16790	COG3620	sequence-specific DNA binding
NQ528_16810	COG0840	transmembrane signaling receptor activity
NQ528_16820	COG2183	response to ionizing radiation
NQ528_16830	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
NQ528_16840	COG0463	Glycosyl transferase, family 2
NQ528_16845	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
NQ528_16850	COG0037	tRNA processing
NQ528_16875	COG2502	aspartate--ammonia ligase
NQ528_16885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
NQ528_16895	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NQ528_16905	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
NQ528_16925	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NQ528_16930	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NQ528_16945	COG0203	ribosomal protein L17
NQ528_16950	COG0202	RNA polymerase activity
NQ528_16955	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NQ528_16965	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NQ528_16970	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NQ528_16975	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NQ528_16985	COG0024	Methionine aminopeptidase
NQ528_16990	COG0563	adenylate kinase activity
NQ528_17000	COG0200	Binds to the 23S rRNA
NQ528_17010	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NQ528_17015	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
NQ528_17020	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NQ528_17025	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NQ528_17030	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NQ528_17035	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NQ528_17040	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NQ528_17045	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NQ528_17050	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
NQ528_17055	COG0255	Belongs to the universal ribosomal protein uL29 family
NQ528_17060	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NQ528_17065	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NQ528_17070	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NQ528_17075	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NQ528_17085	COG0089	rRNA binding
NQ528_17090	COG0088	Forms part of the polypeptide exit tunnel
NQ528_17095	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NQ528_17100	COG0051	transcription antitermination factor activity, RNA binding
NQ528_17110	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NQ528_17125	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
NQ528_17130	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
NQ528_17135	COG1028	Short-chain dehydrogenase reductase Sdr
NQ528_17140	COG2070	2-Nitropropane dioxygenase
NQ528_17145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
NQ528_17150	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NQ528_17155	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NQ528_17160	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NQ528_17170	COG1592	Rubrerythrin
NQ528_17185	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NQ528_17190	COG0456	acetyltransferase
NQ528_17195	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NQ528_17195	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NQ528_17205	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NQ528_17210	COG0440	acetolactate synthase activity
NQ528_17215	COG0028	Belongs to the TPP enzyme family
NQ528_17225	COG4607	ABC-type enterochelin transport system periplasmic component
NQ528_17230	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
NQ528_17235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NQ528_17240	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
NQ528_17245	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
NQ528_17250	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
NQ528_17260	COG0137	argininosuccinate synthase activity
NQ528_17270	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NQ528_17290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NQ528_17325	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NQ528_17330	COG0561	phosphatase activity
NQ528_17395	COG1966	Carbon starvation protein
NQ528_17430	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NQ528_17440	COG1609	Transcriptional regulator
NQ528_17445	COG0167	dihydroorotate dehydrogenase activity
NQ528_17450	COG2233	PERMEase
NQ528_17460	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NQ528_17465	COG0402	S-adenosylhomocysteine deaminase activity
NQ528_17475	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NQ528_17485	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NQ528_17535	COG0714	Associated with various cellular activities
NQ528_17545	COG3552	Protein containing von Willebrand factor type A (VWA) domain
NQ528_17565	COG2217	Heavy metal translocating P-type atpase
NQ528_17570	COG2217	Heavy metal translocating P-type atpase
NQ528_17590	COG0058	SHG alpha-glucan phosphorylase activity
NQ528_17595	COG1640	4-alpha-glucanotransferase
NQ528_17600	COG0622	Phosphoesterase
NQ528_17620	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
NQ528_17630	COG2890	protein-(glutamine-N5) methyltransferase activity
NQ528_17635	COG2768	binding domain, Protein
NQ528_17640	COG1774	PSP1 C-terminal conserved region
NQ528_17650	COG3870	Protein conserved in bacteria
NQ528_17655	COG1982	Orn Lys Arg decarboxylase major
NQ528_17675	COG0569	domain protein
NQ528_17695	COG0488	(ABC) transporter
NQ528_17765	COG1216	Glycosyl transferase, family 2
NQ528_17770	COG1215	transferase activity, transferring glycosyl groups
NQ528_17800	COG1216	Glycosyl transferase, family 2
NQ528_17800	COG0438	transferase activity, transferring glycosyl groups
NQ528_17815	COG1091	dTDP-4-dehydrorhamnose reductase activity
NQ528_17820	COG0463	Glycosyl transferase, family 2
NQ528_17825	COG1088	dTDP-glucose 4,6-dehydratase activity
NQ528_17845	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
NQ528_17865	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NQ528_17870	COG1475	DNA binding
NQ528_17875	COG1192	Involved in chromosome partitioning
NQ528_17880	COG1475	DNA binding
NQ528_17885	COG0357	Ribosomal RNA small subunit methyltransferase G
NQ528_17890	COG0445	tRNA wobble uridine modification
NQ528_17895	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
NQ528_17900	COG1847	R3H domain protein
NQ528_17910	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NQ528_17915	COG0594	ribonuclease P activity
NQ528_17920	COG0230	Belongs to the bacterial ribosomal protein bL34 family