locus-tag	class	description
ETAA8_00010	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ETAA8_00020	COG0592	DNA-directed DNA polymerase activity
ETAA8_00110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA8_00520	COG2186	Transcriptional regulator
ETAA8_00530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ETAA8_00540	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETAA8_00560	COG0179	Fumarylacetoacetate (FAA) hydrolase
ETAA8_00590	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_00600	COG0022	dehydrogenase e1 component
ETAA8_00650	COG2186	Transcriptional regulator
ETAA8_00730	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETAA8_00740	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_00820	COG1525	nuclease
ETAA8_00930	COG0673	inositol 2-dehydrogenase activity
ETAA8_00950	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_00980	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_01000	COG2186	Transcriptional regulator
ETAA8_01100	COG0673	inositol 2-dehydrogenase activity
ETAA8_01160	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_01390	COG0673	inositol 2-dehydrogenase activity
ETAA8_01430	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ETAA8_01440	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ETAA8_01450	COG0363	glucosamine-6-phosphate deaminase activity
ETAA8_01540	COG0515	serine threonine protein kinase
ETAA8_01540	COG2815	serine threonine protein kinase
ETAA8_01580	COG2815	serine threonine protein kinase
ETAA8_01580	COG0515	serine threonine protein kinase
ETAA8_01670	COG3119	arylsulfatase activity
ETAA8_01770	COG1846	Transcriptional regulator
ETAA8_01770	COG1940	carbohydrate kinase activity
ETAA8_01800	COG0129	dihydroxy-acid dehydratase activity
ETAA8_02000	COG0542	response to heat
ETAA8_02030	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ETAA8_02080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA8_02120	COG1966	Carbon starvation protein
ETAA8_02160	COG0673	inositol 2-dehydrogenase activity
ETAA8_02190	COG1595	DNA-templated transcription, initiation
ETAA8_02210	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ETAA8_02240	COG0531	amino acid
ETAA8_02310	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ETAA8_02350	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETAA8_02390	COG0657	acetylesterase activity
ETAA8_02390	COG2755	lipolytic protein G-D-S-L family
ETAA8_02440	COG2195	Cleaves the N-terminal amino acid of tripeptides
ETAA8_02460	COG0438	transferase activity, transferring glycosyl groups
ETAA8_02510	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ETAA8_02520	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ETAA8_02530	COG3842	ATPase activity
ETAA8_02540	COG0195	Participates in both transcription termination and antitermination
ETAA8_02550	COG0616	signal peptide processing
ETAA8_02610	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ETAA8_02620	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETAA8_02670	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_02840	COG2201	protein-glutamate methylesterase activity
ETAA8_02920	COG1285	pathogenesis
ETAA8_02940	COG2226	methyltransferase
ETAA8_03000	COG1381	Involved in DNA repair and RecF pathway recombination
ETAA8_03060	COG4191	Histidine kinase
ETAA8_03070	COG1872	DUF167
ETAA8_03080	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_03100	COG0318	PFAM AMP-dependent synthetase and ligase
ETAA8_03130	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ETAA8_03150	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ETAA8_03160	COG0493	'glutamate synthase
ETAA8_03280	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETAA8_03290	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETAA8_03300	COG2133	pyrroloquinoline quinone binding
ETAA8_03350	COG3002	Belongs to the UPF0753 family
ETAA8_03360	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ETAA8_03370	COG1007	ATP synthesis coupled electron transport
ETAA8_03420	COG4797	methyltransferase
ETAA8_03420	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ETAA8_03450	COG0584	glycerophosphoryl diester phosphodiesterase
ETAA8_03480	COG0612	Peptidase, M16
ETAA8_03490	COG0456	acetyltransferase
ETAA8_03570	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ETAA8_03770	COG0723	plastoquinol--plastocyanin reductase activity
ETAA8_03770	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETAA8_03780	COG0300	oxidoreductase activity
ETAA8_03820	COG0745	RESPONSE REGULATOR receiver
ETAA8_03870	COG0811	peptide transport
ETAA8_03910	COG1595	DNA-templated transcription, initiation
ETAA8_03950	COG0205	6-phosphofructokinase activity
ETAA8_03980	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
ETAA8_03990	COG0475	glutathione-regulated potassium exporter activity
ETAA8_04030	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ETAA8_04040	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ETAA8_04160	COG1943	Transposase
ETAA8_04170	COG0113	porphobilinogen synthase activity
ETAA8_04210	COG1858	cytochrome C peroxidase
ETAA8_04220	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
ETAA8_04230	COG2226	methyltransferase
ETAA8_04240	COG1741	Belongs to the pirin family
ETAA8_04250	COG1335	isochorismatase
ETAA8_04280	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ETAA8_04310	COG2022	thiamine diphosphate biosynthetic process
ETAA8_04330	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_04400	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ETAA8_04410	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ETAA8_04540	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETAA8_04640	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ETAA8_04650	COG0640	Transcriptional regulator
ETAA8_04660	COG0810	Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins
ETAA8_04680	COG1671	Belongs to the UPF0178 family
ETAA8_04740	COG1418	mRNA catabolic process
ETAA8_04750	COG1692	metallophosphoesterase
ETAA8_04850	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ETAA8_04880	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ETAA8_04910	COG1695	Transcriptional regulator
ETAA8_04940	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETAA8_04950	COG1366	Belongs to the anti-sigma-factor antagonist family
ETAA8_05010	COG3119	arylsulfatase activity
ETAA8_05080	COG0515	serine threonine protein kinase
ETAA8_05080	COG2815	serine threonine protein kinase
ETAA8_05090	COG2076	Multidrug Resistance protein
ETAA8_05120	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
ETAA8_05180	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ETAA8_05190	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ETAA8_05230	COG3119	arylsulfatase activity
ETAA8_05240	COG3119	arylsulfatase activity
ETAA8_05320	COG1082	Xylose isomerase domain protein TIM barrel
ETAA8_05350	COG2832	Protein of unknown function (DUF454)
ETAA8_05420	COG1131	(ABC) transporter
ETAA8_05450	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ETAA8_05490	COG1530	ribonuclease E activity
ETAA8_05530	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ETAA8_05550	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ETAA8_05580	COG1361	Conserved repeat domain
ETAA8_05660	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_05730	COG0473	3-isopropylmalate dehydrogenase activity
ETAA8_05760	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ETAA8_05770	COG0318	PFAM AMP-dependent synthetase and ligase
ETAA8_05780	COG3408	Glycogen debranching enzyme
ETAA8_05780	COG3119	arylsulfatase activity
ETAA8_05800	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ETAA8_05950	COG2070	2-Nitropropane dioxygenase
ETAA8_06050	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_06050	COG0515	serine threonine protein kinase
ETAA8_06110	COG2815	serine threonine protein kinase
ETAA8_06110	COG0515	serine threonine protein kinase
ETAA8_06240	COG0515	serine threonine protein kinase
ETAA8_06240	COG2815	serine threonine protein kinase
ETAA8_06270	COG1174	glycine betaine transport
ETAA8_06280	COG0517	IMP dehydrogenase activity
ETAA8_06280	COG1125	glycine betaine transport
ETAA8_06420	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ETAA8_06430	COG1058	Belongs to the CinA family
ETAA8_06430	COG1546	Belongs to the CinA family
ETAA8_06460	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ETAA8_06840	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ETAA8_06850	COG0509	glycine decarboxylation via glycine cleavage system
ETAA8_06870	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ETAA8_06930	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ETAA8_07080	COG2815	serine threonine protein kinase
ETAA8_07080	COG0515	serine threonine protein kinase
ETAA8_07250	COG0180	Tryptophanyl-tRNA synthetase
ETAA8_07280	COG0776	regulation of translation
ETAA8_07290	COG0727	PFAM Uncharacterised protein family (UPF0153)
ETAA8_07320	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ETAA8_07340	COG2323	membrane
ETAA8_07360	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ETAA8_07370	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ETAA8_07380	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ETAA8_07410	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
ETAA8_07450	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ETAA8_07480	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ETAA8_07500	COG1899	peptidyl-lysine modification to peptidyl-hypusine
ETAA8_07550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ETAA8_07560	COG1309	transcriptional regulator
ETAA8_07570	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ETAA8_07700	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ETAA8_07730	COG1858	cytochrome C peroxidase
ETAA8_07790	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ETAA8_07810	COG4948	Mandelate Racemase Muconate Lactonizing
ETAA8_07860	COG1131	(ABC) transporter
ETAA8_07980	COG0515	serine threonine protein kinase
ETAA8_07980	COG2815	serine threonine protein kinase
ETAA8_08000	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ETAA8_08030	COG1643	Atp-dependent helicase
ETAA8_08040	COG3852	Histidine kinase
ETAA8_08050	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETAA8_08110	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
ETAA8_08120	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETAA8_08130	COG0243	molybdopterin cofactor binding
ETAA8_08140	COG0437	4 iron, 4 sulfur cluster binding
ETAA8_08150	COG1116	anion transmembrane transporter activity
ETAA8_08160	COG1116	anion transmembrane transporter activity
ETAA8_08170	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ETAA8_08180	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ETAA8_08200	COG2204	response regulator
ETAA8_08210	COG2205	protein histidine kinase activity
ETAA8_08210	COG0784	Response regulator, receiver
ETAA8_08210	COG2198	Histidine kinase
ETAA8_08240	COG2169	Transcriptional regulator
ETAA8_08270	COG0657	acetylesterase activity
ETAA8_08280	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ETAA8_08310	COG0848	biopolymer transport protein
ETAA8_08320	COG0811	peptide transport
ETAA8_08380	COG0861	Integral membrane protein TerC family
ETAA8_08400	COG0784	Response regulator, receiver
ETAA8_08400	COG2205	protein histidine kinase activity
ETAA8_08400	COG5002	protein histidine kinase activity
ETAA8_08440	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ETAA8_08450	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ETAA8_08460	COG1596	polysaccharide export
ETAA8_08480	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ETAA8_08480	COG1793	dna ligase
ETAA8_08490	COG1968	undecaprenyl-diphosphatase activity
ETAA8_08500	COG1090	epimerase
ETAA8_08540	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ETAA8_08650	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ETAA8_08690	COG1136	(ABC) transporter
ETAA8_08710	COG0151	Belongs to the GarS family
ETAA8_08720	COG2176	DNA-directed DNA polymerase activity
ETAA8_08870	COG4227	nucleotidyltransferase activity
ETAA8_08930	COG4974	Belongs to the 'phage' integrase family
ETAA8_08950	COG2255	four-way junction helicase activity
ETAA8_09040	COG4977	sequence-specific DNA binding
ETAA8_09050	COG3059	membrane
ETAA8_09060	COG2204	response regulator
ETAA8_09100	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ETAA8_09150	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETAA8_09250	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ETAA8_09340	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ETAA8_09760	COG3622	Belongs to the hyi family
ETAA8_09780	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
ETAA8_09800	COG2378	regulation of single-species biofilm formation
ETAA8_09850	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ETAA8_09930	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETAA8_09950	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA8_09980	COG0546	phosphoglycolate phosphatase activity
ETAA8_10010	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ETAA8_10050	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ETAA8_10070	COG2204	response regulator
ETAA8_10090	COG0165	Argininosuccinate lyase
ETAA8_10110	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ETAA8_10130	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ETAA8_10170	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETAA8_10210	COG2814	Major facilitator Superfamily
ETAA8_10230	COG4964	Belongs to the GSP D family
ETAA8_10260	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ETAA8_10320	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ETAA8_10440	COG1448	Aminotransferase
ETAA8_10460	COG2706	6-phosphogluconolactonase activity
ETAA8_10630	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ETAA8_10670	COG2363	Small membrane protein
ETAA8_10700	COG0163	prenyltransferase activity
ETAA8_10710	COG2226	methyltransferase
ETAA8_10780	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ETAA8_10790	COG1053	succinate dehydrogenase
ETAA8_10800	COG2009	succinate dehydrogenase
ETAA8_10900	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ETAA8_10910	COG1136	(ABC) transporter
ETAA8_10910	COG0577	efflux transmembrane transporter activity
ETAA8_10930	COG3875	lactate racemase activity
ETAA8_10960	COG0693	protein deglycase activity
ETAA8_11000	COG2261	transglycosylase associated protein
ETAA8_11120	COG0745	RESPONSE REGULATOR receiver
ETAA8_11160	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETAA8_11190	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ETAA8_11210	COG0571	ribonuclease III activity
ETAA8_11250	COG0673	inositol 2-dehydrogenase activity
ETAA8_11280	COG4964	Belongs to the GSP D family
ETAA8_11330	COG0028	Belongs to the TPP enzyme family
ETAA8_11380	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETAA8_11390	COG3622	Belongs to the hyi family
ETAA8_11440	COG0284	orotidine-5'-phosphate decarboxylase activity
ETAA8_11450	COG0742	ribosomal rna small subunit methyltransferase
ETAA8_11470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_11570	COG5002	protein histidine kinase activity
ETAA8_11590	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ETAA8_11600	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETAA8_11630	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ETAA8_11660	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_11670	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_11680	COG0488	(ABC) transporter
ETAA8_11700	COG0521	Mo-molybdopterin cofactor biosynthetic process
ETAA8_11760	COG0525	valine-tRNA ligase activity
ETAA8_11820	COG0653	protein targeting
ETAA8_11840	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ETAA8_11850	COG0052	Belongs to the universal ribosomal protein uS2 family
ETAA8_11890	COG1131	(ABC) transporter
ETAA8_12000	COG3437	response regulator, receiver
ETAA8_12010	COG0004	ammonium transporteR
ETAA8_12040	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ETAA8_12050	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ETAA8_12130	COG0183	Belongs to the thiolase family
ETAA8_12140	COG1024	Enoyl-CoA hydratase
ETAA8_12140	COG1250	3-hydroxyacyl-CoA dehydrogenase
ETAA8_12190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETAA8_12200	COG1459	type II secretion system
ETAA8_12210	COG2165	general secretion pathway protein
ETAA8_12280	COG1450	Type ii and iii secretion system protein
ETAA8_12320	COG2204	response regulator
ETAA8_12330	COG5487	UPF0391 membrane protein
ETAA8_12340	COG3237	CsbD-like
ETAA8_12360	COG0783	Belongs to the Dps family
ETAA8_12390	COG0667	Aldo Keto reductase
ETAA8_12400	COG1136	(ABC) transporter
ETAA8_12440	COG2140	Oxalate decarboxylase
ETAA8_12450	COG0783	Belongs to the Dps family
ETAA8_12480	COG0515	serine threonine protein kinase
ETAA8_12480	COG2815	serine threonine protein kinase
ETAA8_12500	COG2814	Major facilitator Superfamily
ETAA8_12520	COG0588	phosphoglycerate mutase activity
ETAA8_12580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETAA8_12590	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_12620	COG3119	arylsulfatase activity
ETAA8_12630	COG3119	arylsulfatase activity
ETAA8_12700	COG0477	Major facilitator Superfamily
ETAA8_12850	COG2205	protein histidine kinase activity
ETAA8_12870	COG5002	protein histidine kinase activity
ETAA8_12890	COG2204	response regulator
ETAA8_12910	COG0148	phosphopyruvate hydratase activity
ETAA8_12920	COG0148	phosphopyruvate hydratase activity
ETAA8_12980	COG2378	regulation of single-species biofilm formation
ETAA8_13040	COG1484	DNA-dependent DNA replication
ETAA8_13110	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_13240	COG0668	transmembrane transport
ETAA8_13270	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ETAA8_13290	COG3119	arylsulfatase activity
ETAA8_13410	COG3344	reverse transcriptase
ETAA8_13510	COG0210	DNA helicase
ETAA8_13550	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ETAA8_13600	COG0247	lactate metabolic process
ETAA8_13620	COG0733	neurotransmitter:sodium symporter activity
ETAA8_13640	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETAA8_13650	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ETAA8_13680	COG0205	6-phosphofructokinase activity
ETAA8_13710	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ETAA8_13790	COG3458	cephalosporin-C deacetylase activity
ETAA8_13820	COG0673	inositol 2-dehydrogenase activity
ETAA8_13840	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
ETAA8_13890	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ETAA8_13910	COG0564	pseudouridine synthase activity
ETAA8_13940	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ETAA8_13960	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ETAA8_13970	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ETAA8_14040	COG0515	serine threonine protein kinase
ETAA8_14040	COG2815	serine threonine protein kinase
ETAA8_14070	COG1073	alpha beta
ETAA8_14110	COG2096	Adenosyltransferase
ETAA8_14130	COG2738	Putative neutral zinc metallopeptidase
ETAA8_14160	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ETAA8_14170	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_14180	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETAA8_14190	COG5285	phytanoyl-CoA dioxygenase
ETAA8_14210	COG1970	mechanosensitive ion channel activity
ETAA8_14220	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ETAA8_14230	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ETAA8_14260	COG1131	(ABC) transporter
ETAA8_14270	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ETAA8_14290	COG3012	SEC-C Motif Domain Protein
ETAA8_14320	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ETAA8_14450	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ETAA8_14470	COG4191	Histidine kinase
ETAA8_14490	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ETAA8_14500	COG0247	lactate metabolic process
ETAA8_14510	COG1139	Iron-sulfur cluster binding protein
ETAA8_14520	COG1556	Lactate utilization protein
ETAA8_14530	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ETAA8_14540	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ETAA8_14550	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ETAA8_14550	COG3608	succinylglutamate desuccinylase aspartoacylase
ETAA8_14560	COG1359	(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity
ETAA8_14580	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ETAA8_14590	COG0631	protein serine/threonine phosphatase activity
ETAA8_14600	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ETAA8_14680	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ETAA8_14830	COG1797	cobyrinic acid a,c-diamide synthase activity
ETAA8_14920	COG3118	belongs to the thioredoxin family
ETAA8_14940	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ETAA8_14960	COG0626	cystathionine gamma-synthase activity
ETAA8_15000	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ETAA8_15020	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ETAA8_15080	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_15160	COG0717	Belongs to the dCTP deaminase family
ETAA8_15170	COG2814	Major facilitator Superfamily
ETAA8_15200	COG1045	serine acetyltransferase
ETAA8_15220	COG1104	cysteine desulfurase activity
ETAA8_15240	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETAA8_15240	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETAA8_15280	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ETAA8_15360	COG1064	alcohol dehydrogenase
ETAA8_15380	COG3119	arylsulfatase activity
ETAA8_15390	COG3119	arylsulfatase activity
ETAA8_15400	COG3119	arylsulfatase activity
ETAA8_15420	COG3119	arylsulfatase activity
ETAA8_15430	COG0736	holo-[acyl-carrier-protein] synthase activity
ETAA8_15480	COG0444	Belongs to the ABC transporter superfamily
ETAA8_15490	COG4608	Belongs to the ABC transporter superfamily
ETAA8_15530	COG0673	inositol 2-dehydrogenase activity
ETAA8_15540	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ETAA8_15550	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ETAA8_15570	COG0673	inositol 2-dehydrogenase activity
ETAA8_15620	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
ETAA8_15630	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ETAA8_15690	COG0515	serine threonine protein kinase
ETAA8_15780	COG1073	alpha beta
ETAA8_15850	COG1253	flavin adenine dinucleotide binding
ETAA8_15890	COG1716	ATPase activity
ETAA8_15910	COG3264	Mechanosensitive ion channel
ETAA8_15910	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ETAA8_15920	COG0598	Magnesium transport protein CorA
ETAA8_15930	COG0720	synthase
ETAA8_15940	COG0488	(ABC) transporter
ETAA8_16040	COG2234	aminopeptidase activity
ETAA8_16060	COG4974	Belongs to the 'phage' integrase family
ETAA8_16120	COG0732	type I restriction modification DNA specificity domain
ETAA8_16420	COG2706	6-phosphogluconolactonase activity
ETAA8_16610	COG0515	serine threonine protein kinase
ETAA8_16610	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_16680	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_16840	COG1484	DNA-dependent DNA replication
ETAA8_16860	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ETAA8_16920	COG2319	Wd-40 repeat
ETAA8_16920	COG5635	Nacht domain
ETAA8_17070	COG3119	arylsulfatase activity
ETAA8_17190	COG2217	Heavy metal translocating P-type atpase
ETAA8_17220	COG1484	DNA-dependent DNA replication
ETAA8_17250	COG4974	Belongs to the 'phage' integrase family
ETAA8_17350	COG1595	DNA-templated transcription, initiation
ETAA8_17390	COG2217	Heavy metal translocating P-type atpase
ETAA8_17440	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ETAA8_17450	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ETAA8_17450	COG2755	lipolytic protein G-D-S-L family
ETAA8_17520	COG2226	methyltransferase
ETAA8_17530	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETAA8_17540	COG1104	cysteine desulfurase activity
ETAA8_17550	COG0640	Transcriptional regulator
ETAA8_17630	COG0477	Major facilitator Superfamily
ETAA8_17720	COG5433	transposase activity
ETAA8_17740	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_17820	COG1136	(ABC) transporter
ETAA8_17830	COG0577	efflux transmembrane transporter activity
ETAA8_17870	COG2608	mercury ion transmembrane transporter activity
ETAA8_17890	COG1742	UPF0060 membrane protein
ETAA8_17970	COG0515	serine threonine protein kinase
ETAA8_17970	COG2815	serine threonine protein kinase
ETAA8_18040	COG0515	serine threonine protein kinase
ETAA8_18040	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ETAA8_18120	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA8_18180	COG0582	viral genome integration into host DNA
ETAA8_18190	COG0745	RESPONSE REGULATOR receiver
ETAA8_18200	COG2205	protein histidine kinase activity
ETAA8_18210	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ETAA8_18220	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ETAA8_18230	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ETAA8_18270	COG2239	Acts as a magnesium transporter
ETAA8_18310	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ETAA8_18340	COG4191	Histidine kinase
ETAA8_18350	COG2204	response regulator
ETAA8_18410	COG0205	6-phosphofructokinase activity
ETAA8_18450	COG2186	Transcriptional regulator
ETAA8_18480	COG1484	DNA-dependent DNA replication
ETAA8_18500	COG0515	serine threonine protein kinase
ETAA8_18520	COG0577	efflux transmembrane transporter activity
ETAA8_18520	COG1136	(ABC) transporter
ETAA8_18580	COG3119	arylsulfatase activity
ETAA8_18640	COG0124	histidyl-tRNA synthetase
ETAA8_18680	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ETAA8_18730	COG0564	pseudouridine synthase activity
ETAA8_18790	COG1073	alpha beta
ETAA8_18800	COG0295	cytidine deaminase activity
ETAA8_18830	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ETAA8_18860	COG0028	Belongs to the TPP enzyme family
ETAA8_18870	COG0659	secondary active sulfate transmembrane transporter activity
ETAA8_18880	COG0288	reversible hydration of carbon dioxide
ETAA8_18910	COG2094	Belongs to the DNA glycosylase MPG family
ETAA8_19040	COG0463	Glycosyl transferase, family 2
ETAA8_19050	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ETAA8_19150	COG3119	arylsulfatase activity
ETAA8_19160	COG1335	isochorismatase
ETAA8_19260	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ETAA8_19270	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETAA8_19340	COG1674	ftsk spoiiie
ETAA8_19360	COG1560	Kdo2-lipid A biosynthetic process
ETAA8_19390	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ETAA8_19420	COG0352	thiamine-phosphate diphosphorylase activity
ETAA8_19430	COG1136	(ABC) transporter
ETAA8_19440	COG4591	ABC-type transport system involved in lipoprotein release permease component
ETAA8_19470	COG1305	Transglutaminase-like
ETAA8_19490	COG4251	negative regulation of phosphorylation
ETAA8_19500	COG0784	Response regulator, receiver
ETAA8_19510	COG5002	protein histidine kinase activity
ETAA8_19560	COG3386	PFAM SMP-30 Gluconolaconase
ETAA8_19580	COG3119	arylsulfatase activity
ETAA8_19600	COG4166	transmembrane transport
ETAA8_19610	COG0601	transmembrane transport
ETAA8_19620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETAA8_19780	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETAA8_19850	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ETAA8_19860	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ETAA8_19910	COG0740	serine-type endopeptidase activity
ETAA8_19920	COG0740	serine-type endopeptidase activity
ETAA8_19960	COG0004	ammonium transporteR
ETAA8_19980	COG0596	Alpha beta hydrolase
ETAA8_20040	COG0719	Fe-S assembly protein
ETAA8_20070	COG0719	Fe-S assembly protein
ETAA8_20080	COG0396	ATPase activity
ETAA8_20090	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA8_20170	COG4968	Prepilin-type N-terminal cleavage methylation domain
ETAA8_20200	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ETAA8_20210	COG1449	Belongs to the glycosyl hydrolase 57 family
ETAA8_20260	COG1136	(ABC) transporter
ETAA8_20260	COG0577	efflux transmembrane transporter activity
ETAA8_20280	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ETAA8_20290	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ETAA8_20370	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETAA8_20390	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ETAA8_20430	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ETAA8_20440	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ETAA8_20450	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ETAA8_20480	COG1582	Flagellar protein (FlbD)
ETAA8_20490	COG1749	Flagellar hook protein flgE
ETAA8_20500	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ETAA8_20540	COG1157	protein secretion by the type III secretion system
ETAA8_20560	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETAA8_20580	COG1677	Flagellar hook-basal body complex protein FliE
ETAA8_20600	COG1815	bacterial-type flagellum-dependent cell motility
ETAA8_20610	COG2204	response regulator
ETAA8_20620	COG3852	Histidine kinase
ETAA8_20670	COG0039	L-malate dehydrogenase activity
ETAA8_20680	COG3228	Belongs to the MtfA family
ETAA8_20710	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ETAA8_20770	COG0367	asparagine synthase
ETAA8_20780	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ETAA8_20840	COG3541	Predicted nucleotidyltransferase
ETAA8_20860	COG0347	Belongs to the P(II) protein family
ETAA8_21030	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ETAA8_21090	COG3118	belongs to the thioredoxin family
ETAA8_21150	COG1450	Type ii and iii secretion system protein
ETAA8_21270	COG0735	belongs to the Fur family
ETAA8_21280	COG0523	cobalamin synthesis protein
ETAA8_21330	COG0673	inositol 2-dehydrogenase activity
ETAA8_21390	COG0784	Response regulator, receiver
ETAA8_21390	COG5002	protein histidine kinase activity
ETAA8_21400	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ETAA8_21410	COG4251	negative regulation of phosphorylation
ETAA8_21420	COG5002	protein histidine kinase activity
ETAA8_21480	COG3119	arylsulfatase activity
ETAA8_21500	COG2124	cytochrome p450
ETAA8_21510	COG2610	gluconate transmembrane transporter activity
ETAA8_21530	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ETAA8_21540	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_21580	COG3119	arylsulfatase activity
ETAA8_21590	COG3119	arylsulfatase activity
ETAA8_21600	COG3119	arylsulfatase activity
ETAA8_21690	COG3119	arylsulfatase activity
ETAA8_21710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ETAA8_21720	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ETAA8_21740	COG4585	Histidine kinase
ETAA8_21750	COG2197	response regulator
ETAA8_21760	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ETAA8_21770	COG1595	DNA-templated transcription, initiation
ETAA8_21780	COG0515	serine threonine protein kinase
ETAA8_21780	COG2815	serine threonine protein kinase
ETAA8_21860	COG1007	ATP synthesis coupled electron transport
ETAA8_21890	COG0713	ATP synthesis coupled electron transport
ETAA8_21900	COG0839	Belongs to the complex I subunit 6 family
ETAA8_21910	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA8_21920	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ETAA8_21930	COG1034	ATP synthesis coupled electron transport
ETAA8_21950	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
ETAA8_21960	COG0649	NAD binding
ETAA8_21970	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA8_21980	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA8_21990	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA8_22010	COG1363	Peptidase, m42
ETAA8_22020	COG1091	dTDP-4-dehydrorhamnose reductase activity
ETAA8_22030	COG2264	protein methyltransferase activity
ETAA8_22040	COG2501	S4 domain
ETAA8_22110	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
ETAA8_22150	COG0438	transferase activity, transferring glycosyl groups
ETAA8_22170	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
ETAA8_22190	COG0287	Prephenate dehydrogenase
ETAA8_22330	COG0366	Alpha amylase catalytic
ETAA8_22420	COG0667	Aldo Keto reductase
ETAA8_22720	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ETAA8_22770	COG1506	peptidase
ETAA8_22770	COG0823	Involved in the tonB-independent uptake of proteins
ETAA8_22790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ETAA8_22790	COG0574	Belongs to the PEP-utilizing enzyme family
ETAA8_22820	COG0543	2 iron, 2 sulfur cluster binding
ETAA8_22830	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA8_22840	COG0427	acetyl-CoA hydrolase
ETAA8_22890	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
ETAA8_22920	COG0309	Hydrogenase expression formation protein (HypE)
ETAA8_22940	COG0443	Heat shock 70 kDa protein
ETAA8_22960	COG1959	2 iron, 2 sulfur cluster binding
ETAA8_22970	COG1151	hydroxylamine reductase activity
ETAA8_23010	COG2423	ornithine cyclodeaminase activity
ETAA8_23020	COG2326	polyphosphate kinase activity
ETAA8_23200	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA8_23340	COG3119	arylsulfatase activity
ETAA8_23350	COG0657	acetylesterase activity
ETAA8_23380	COG1754	DNA topoisomerase type I activity
ETAA8_23380	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ETAA8_23470	COG0653	protein targeting
ETAA8_23490	COG0443	Heat shock 70 kDa protein
ETAA8_23530	COG1082	Xylose isomerase domain protein TIM barrel
ETAA8_23560	COG0745	RESPONSE REGULATOR receiver
ETAA8_23630	COG0657	acetylesterase activity
ETAA8_23630	COG2755	lipolytic protein G-D-S-L family
ETAA8_23670	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
ETAA8_23670	COG0493	'glutamate synthase
ETAA8_23680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETAA8_23710	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ETAA8_23870	COG0454	-acetyltransferase
ETAA8_23950	COG0204	Acyl-transferase
ETAA8_23950	COG0318	PFAM AMP-dependent synthetase and ligase
ETAA8_23960	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ETAA8_23970	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ETAA8_23980	COG1722	exodeoxyribonuclease VII activity
ETAA8_23990	COG1570	exodeoxyribonuclease VII activity
ETAA8_24000	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ETAA8_24010	COG1331	Highly conserved protein containing a thioredoxin domain
ETAA8_24020	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ETAA8_24030	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ETAA8_24030	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ETAA8_24110	COG1136	(ABC) transporter
ETAA8_24110	COG0577	efflux transmembrane transporter activity
ETAA8_24130	COG3344	reverse transcriptase
ETAA8_24210	COG0488	(ABC) transporter
ETAA8_24230	COG0726	polysaccharide deacetylase
ETAA8_24420	COG1505	serine-type exopeptidase activity
ETAA8_24450	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ETAA8_24500	COG1691	(AIR) carboxylase
ETAA8_24510	COG0137	argininosuccinate synthase activity
ETAA8_24520	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ETAA8_24580	COG0723	plastoquinol--plastocyanin reductase activity
ETAA8_24610	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ETAA8_24610	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ETAA8_24630	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETAA8_24650	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ETAA8_24700	COG0543	2 iron, 2 sulfur cluster binding
ETAA8_24710	COG1187	pseudouridine synthase activity
ETAA8_24730	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ETAA8_24750	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETAA8_24800	COG0423	glycine-tRNA ligase activity
ETAA8_24810	COG2045	Belongs to the ComB family
ETAA8_24820	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ETAA8_24830	COG1597	lipid kinase activity
ETAA8_24850	COG1136	(ABC) transporter
ETAA8_24880	COG0424	maF-like protein
ETAA8_24920	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETAA8_24930	COG0681	Belongs to the peptidase S26 family
ETAA8_24940	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ETAA8_24950	COG4948	Mandelate Racemase Muconate Lactonizing
ETAA8_25030	COG0436	Aminotransferase
ETAA8_25070	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ETAA8_25120	COG0165	Argininosuccinate lyase
ETAA8_25170	COG0488	(ABC) transporter
ETAA8_25240	COG2133	pyrroloquinoline quinone binding
ETAA8_25260	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_25340	COG0657	acetylesterase activity
ETAA8_25350	COG0006	proline dipeptidase activity
ETAA8_25380	COG0436	Aminotransferase
ETAA8_25410	COG1073	alpha beta
ETAA8_25420	COG2890	protein-(glutamine-N5) methyltransferase activity
ETAA8_25500	COG5002	protein histidine kinase activity
ETAA8_25570	COG1490	D-aminoacyl-tRNA deacylase activity
ETAA8_25670	COG0038	chloride channel
ETAA8_25680	COG0825	malonyl-CoA metabolic process
ETAA8_25690	COG0515	serine threonine protein kinase
ETAA8_25690	COG2815	serine threonine protein kinase
ETAA8_25700	COG0167	dihydroorotate dehydrogenase activity
ETAA8_25720	COG0745	RESPONSE REGULATOR receiver
ETAA8_25800	COG0604	alcohol dehydrogenase
ETAA8_25840	COG1040	competence protein
ETAA8_25870	COG0101	tRNA pseudouridine synthase activity
ETAA8_25970	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETAA8_25990	COG0706	membrane insertase activity
ETAA8_25990	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_26000	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ETAA8_26010	COG0657	acetylesterase activity
ETAA8_26020	COG3119	arylsulfatase activity
ETAA8_26030	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETAA8_26060	COG0673	inositol 2-dehydrogenase activity
ETAA8_26120	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ETAA8_26130	COG0233	cytoplasmic translational termination
ETAA8_26140	COG1058	Belongs to the CinA family
ETAA8_26140	COG1546	Belongs to the CinA family
ETAA8_26150	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETAA8_26230	COG3119	arylsulfatase activity
ETAA8_26280	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ETAA8_26290	COG0297	glycogen (starch) synthase activity
ETAA8_26340	COG0514	ATP-dependent DNA helicase (RecQ)
ETAA8_26370	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ETAA8_26400	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETAA8_26410	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ETAA8_26480	COG0430	RNA-3'-phosphate cyclase activity
ETAA8_26500	COG2815	serine threonine protein kinase
ETAA8_26500	COG0515	serine threonine protein kinase
ETAA8_26510	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ETAA8_26610	COG3243	poly(R)-hydroxyalkanoic acid synthase
ETAA8_26640	COG0443	Heat shock 70 kDa protein
ETAA8_26710	COG0811	peptide transport
ETAA8_26720	COG2205	protein histidine kinase activity
ETAA8_26750	COG0517	IMP dehydrogenase activity
ETAA8_26750	COG0516	GMP reductase activity
ETAA8_26850	COG0564	pseudouridine synthase activity
ETAA8_26870	COG2329	Antibiotic biosynthesis monooxygenase
ETAA8_26900	COG0437	4 iron, 4 sulfur cluster binding
ETAA8_26960	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ETAA8_26970	COG1229	Formylmethanofuran dehydrogenase subunit A
ETAA8_27010	COG1131	(ABC) transporter
ETAA8_27110	COG0268	Binds directly to 16S ribosomal RNA
ETAA8_27230	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETAA8_27240	COG1321	iron dependent repressor
ETAA8_27240	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ETAA8_27250	COG1121	(ABC) transporter
ETAA8_27260	COG0803	Belongs to the bacterial solute-binding protein 9 family
ETAA8_27270	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ETAA8_27300	COG0463	Glycosyl transferase, family 2
ETAA8_27310	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETAA8_27340	COG0628	permease
ETAA8_27370	COG0584	glycerophosphoryl diester phosphodiesterase
ETAA8_27380	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ETAA8_27450	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ETAA8_27540	COG0159	tryptophan synthase activity
ETAA8_27550	COG0133	tryptophan synthase activity
ETAA8_27580	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ETAA8_27590	COG0275	rRNA processing
ETAA8_27640	COG0019	diaminopimelate decarboxylase activity
ETAA8_27650	COG0318	PFAM AMP-dependent synthetase and ligase
ETAA8_27690	COG0405	Gamma-glutamyltransferase
ETAA8_27710	COG1994	Peptidase M50
ETAA8_27780	COG1136	(ABC) transporter
ETAA8_27790	COG0577	efflux transmembrane transporter activity
ETAA8_27860	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ETAA8_27930	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
ETAA8_27930	COG0237	dephospho-CoA kinase activity
ETAA8_27940	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETAA8_27950	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ETAA8_27970	COG2195	Cleaves the N-terminal amino acid of tripeptides
ETAA8_28010	COG4948	Mandelate Racemase Muconate Lactonizing
ETAA8_28030	COG4948	Mandelate Racemase Muconate Lactonizing
ETAA8_28120	COG0805	protein transport
ETAA8_28130	COG1482	cell wall glycoprotein biosynthetic process
ETAA8_28150	COG0830	nickel cation binding
ETAA8_28180	COG0501	Belongs to the peptidase M48B family
ETAA8_28190	COG2205	protein histidine kinase activity
ETAA8_28190	COG3850	Histidine kinase
ETAA8_28190	COG4999	Histidine kinase
ETAA8_28190	COG3437	response regulator, receiver
ETAA8_28290	COG5002	protein histidine kinase activity
ETAA8_28310	COG0488	(ABC) transporter
ETAA8_28390	COG3209	COG3209 Rhs family protein
ETAA8_28400	COG1484	DNA-dependent DNA replication
ETAA8_28570	COG0515	serine threonine protein kinase
ETAA8_28570	COG2815	serine threonine protein kinase
ETAA8_28600	COG1595	DNA-templated transcription, initiation
ETAA8_28690	COG1164	Oligoendopeptidase f
ETAA8_28820	COG1214	PFAM Peptidase M22, glycoprotease
ETAA8_28840	COG4636	protein conserved in cyanobacteria
ETAA8_28920	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ETAA8_28930	COG0440	acetolactate synthase activity
ETAA8_28950	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ETAA8_28960	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ETAA8_28970	COG0154	amidase activity
ETAA8_28980	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ETAA8_28990	COG4636	protein conserved in cyanobacteria
ETAA8_29230	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ETAA8_29250	COG4999	Histidine kinase
ETAA8_29250	COG3850	Histidine kinase
ETAA8_29250	COG2205	protein histidine kinase activity
ETAA8_29250	COG3437	response regulator, receiver
ETAA8_29260	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ETAA8_29310	COG1132	(ABC) transporter
ETAA8_29320	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ETAA8_29320	COG0189	ligase activity
ETAA8_29340	COG0531	amino acid
ETAA8_29350	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ETAA8_29360	COG0509	glycine decarboxylation via glycine cleavage system
ETAA8_29370	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ETAA8_29380	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ETAA8_29390	COG0095	Lipoate-protein ligase
ETAA8_29410	COG1595	DNA-templated transcription, initiation
ETAA8_29470	COG1254	Belongs to the acylphosphatase family
ETAA8_29490	COG0564	pseudouridine synthase activity
ETAA8_29550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_29560	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ETAA8_29570	COG0346	lactoylglutathione lyase activity
ETAA8_29610	COG4589	Belongs to the CDS family
ETAA8_29720	COG0657	acetylesterase activity
ETAA8_29780	COG0148	phosphopyruvate hydratase activity
ETAA8_29800	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_29820	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
ETAA8_29830	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ETAA8_29870	COG4993	Dehydrogenase
ETAA8_29880	COG3119	arylsulfatase activity
ETAA8_29910	COG3119	arylsulfatase activity
ETAA8_29940	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ETAA8_29960	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
ETAA8_29960	COG2755	lipolytic protein G-D-S-L family
ETAA8_30010	COG1063	alcohol dehydrogenase
ETAA8_30130	COG0542	response to heat
ETAA8_30140	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_30170	COG0714	Associated with various cellular activities
ETAA8_30280	COG5564	TIM-barrel signal transduction protein
ETAA8_30290	COG4762	Protein conserved in bacteria
ETAA8_30400	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ETAA8_30500	COG0659	secondary active sulfate transmembrane transporter activity
ETAA8_30520	COG1012	belongs to the aldehyde dehydrogenase family
ETAA8_30530	COG0438	transferase activity, transferring glycosyl groups
ETAA8_30540	COG0438	transferase activity, transferring glycosyl groups
ETAA8_30590	COG3408	Glycogen debranching enzyme
ETAA8_30590	COG3119	arylsulfatase activity
ETAA8_30660	COG2319	Wd-40 repeat
ETAA8_30740	COG0745	RESPONSE REGULATOR receiver
ETAA8_30760	COG0039	L-malate dehydrogenase activity
ETAA8_30790	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ETAA8_30800	COG0539	negative regulation of cytoplasmic translation
ETAA8_30800	COG2183	response to ionizing radiation
ETAA8_30860	COG0587	DNA-directed DNA polymerase activity
ETAA8_30900	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ETAA8_30910	COG0321	lipoyl(octanoyl) transferase activity
ETAA8_30960	COG0594	ribonuclease P activity
ETAA8_30970	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ETAA8_30990	COG4537	Required for transformation and DNA binding
ETAA8_31010	COG1858	cytochrome C peroxidase
ETAA8_31060	COG0432	Pfam Uncharacterised protein family UPF0047
ETAA8_31080	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ETAA8_31090	COG0483	inositol monophosphate 1-phosphatase activity
ETAA8_31120	COG0459	protein refolding
ETAA8_31130	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ETAA8_31150	COG0556	nucleotide-excision repair
ETAA8_31190	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_31200	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETAA8_31200	COG0300	oxidoreductase activity
ETAA8_31200	COG3321	synthase
ETAA8_31200	COG4221	oxidoreductase activity
ETAA8_31210	COG3320	Male sterility
ETAA8_31210	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETAA8_31220	COG3119	arylsulfatase activity
ETAA8_31380	COG0071	Belongs to the small heat shock protein (HSP20) family
ETAA8_31450	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ETAA8_31460	COG5002	protein histidine kinase activity
ETAA8_31510	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ETAA8_31520	COG0662	Cupin 2, conserved barrel domain protein
ETAA8_31530	COG1272	protein, Hemolysin III
ETAA8_31540	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
ETAA8_31550	COG0628	permease
ETAA8_31620	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ETAA8_31630	COG2205	protein histidine kinase activity
ETAA8_31630	COG0784	Response regulator, receiver
ETAA8_31680	COG0714	Associated with various cellular activities
ETAA8_31770	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_31790	COG1834	amidinotransferase
ETAA8_31890	COG0024	Methionine aminopeptidase
ETAA8_32010	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ETAA8_32040	COG2226	methyltransferase
ETAA8_32050	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ETAA8_32070	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
ETAA8_32080	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ETAA8_32230	COG0657	acetylesterase activity
ETAA8_32270	COG0463	Glycosyl transferase, family 2
ETAA8_32390	COG1271	oxidase subunit
ETAA8_32400	COG1294	oxidase, subunit
ETAA8_32510	COG4968	Prepilin-type N-terminal cleavage methylation domain
ETAA8_32530	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ETAA8_32550	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ETAA8_32560	COG0494	nUDIX hydrolase
ETAA8_32570	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ETAA8_32590	COG0673	inositol 2-dehydrogenase activity
ETAA8_32630	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_32670	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ETAA8_32680	COG1078	dGTPase activity
ETAA8_32750	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ETAA8_32760	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ETAA8_32820	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ETAA8_32840	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ETAA8_32850	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ETAA8_32860	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ETAA8_32870	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ETAA8_33020	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ETAA8_33020	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ETAA8_33160	COG1335	isochorismatase
ETAA8_33180	COG1252	NADH dehydrogenase
ETAA8_33230	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ETAA8_33240	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ETAA8_33270	COG2010	Cytochrome c
ETAA8_33290	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ETAA8_33320	COG0574	Belongs to the PEP-utilizing enzyme family
ETAA8_33320	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ETAA8_33430	COG0617	tRNA 3'-terminal CCA addition
ETAA8_33490	COG0436	Aminotransferase
ETAA8_33500	COG0505	Belongs to the CarA family
ETAA8_33540	COG0745	RESPONSE REGULATOR receiver
ETAA8_33600	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ETAA8_33630	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ETAA8_33630	COG0539	negative regulation of cytoplasmic translation
ETAA8_33680	COG2066	Belongs to the glutaminase family
ETAA8_33730	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ETAA8_33740	COG0590	tRNA wobble adenosine to inosine editing
ETAA8_33750	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ETAA8_33760	COG2080	2 iron, 2 sulfur cluster binding
ETAA8_33810	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ETAA8_33840	COG0584	glycerophosphoryl diester phosphodiesterase
ETAA8_33850	COG0456	acetyltransferase
ETAA8_33870	COG1404	Belongs to the peptidase S8 family
ETAA8_33900	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETAA8_33910	COG3386	PFAM SMP-30 Gluconolaconase
ETAA8_33920	COG0784	Response regulator, receiver
ETAA8_33920	COG2205	protein histidine kinase activity
ETAA8_33930	COG3527	Alpha-acetolactate decarboxylase
ETAA8_33970	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETAA8_34010	COG2815	serine threonine protein kinase
ETAA8_34010	COG0515	serine threonine protein kinase
ETAA8_34100	COG1505	serine-type exopeptidase activity
ETAA8_34170	COG0438	transferase activity, transferring glycosyl groups
ETAA8_34180	COG0275	rRNA processing
ETAA8_34230	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ETAA8_34250	COG3253	May function as heme-dependent peroxidase
ETAA8_34290	COG3119	arylsulfatase activity
ETAA8_34370	COG0673	inositol 2-dehydrogenase activity
ETAA8_34400	COG3459	Glycosyltransferase 36 associated
ETAA8_34430	COG4191	Histidine kinase
ETAA8_34440	COG2204	response regulator
ETAA8_34520	COG2719	SpoVR family
ETAA8_34530	COG2718	Belongs to the UPF0229 family
ETAA8_34540	COG2766	serine protein kinase
ETAA8_34550	COG0445	tRNA wobble uridine modification
ETAA8_34560	COG2217	Heavy metal translocating P-type atpase
ETAA8_34590	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ETAA8_34600	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ETAA8_34680	COG0515	serine threonine protein kinase
ETAA8_34680	COG2815	serine threonine protein kinase
ETAA8_34730	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ETAA8_34740	COG0406	alpha-ribazole phosphatase activity
ETAA8_34750	COG0673	inositol 2-dehydrogenase activity
ETAA8_34840	COG0275	rRNA processing
ETAA8_34850	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ETAA8_34910	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ETAA8_34920	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ETAA8_34970	COG0604	alcohol dehydrogenase
ETAA8_34980	COG3118	belongs to the thioredoxin family
ETAA8_34990	COG0714	Associated with various cellular activities
ETAA8_35070	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ETAA8_35080	COG0793	Belongs to the peptidase S41A family
ETAA8_35160	COG1597	lipid kinase activity
ETAA8_35160	COG1803	Methylglyoxal synthase
ETAA8_35170	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ETAA8_35200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ETAA8_35210	COG0698	ribose 5-phosphate isomerase
ETAA8_35290	COG0006	proline dipeptidase activity
ETAA8_35310	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ETAA8_35340	COG3685	Protein conserved in bacteria
ETAA8_35350	COG1054	Belongs to the UPF0176 family
ETAA8_35370	COG1070	Carbohydrate kinase
ETAA8_35390	COG0357	Ribosomal RNA small subunit methyltransferase G
ETAA8_35410	COG0412	Dienelactone hydrolase
ETAA8_35640	COG0457	Tetratricopeptide repeat
ETAA8_35640	COG0515	serine threonine protein kinase
ETAA8_35760	COG0084	hydrolase, TatD family'
ETAA8_35780	COG1007	ATP synthesis coupled electron transport
ETAA8_35810	COG0713	ATP synthesis coupled electron transport
ETAA8_35820	COG0839	Belongs to the complex I subunit 6 family
ETAA8_35830	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ETAA8_35860	COG2379	hydroxypyruvate reductase
ETAA8_35880	COG2198	Histidine kinase
ETAA8_35880	COG0643	Histidine kinase
ETAA8_35900	COG4941	Belongs to the sigma-70 factor family
ETAA8_35910	COG3795	YCII-related domain
ETAA8_35920	COG3795	YCII-related domain
ETAA8_35930	COG3795	YCII-related domain
ETAA8_36010	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_36020	COG3540	Alkaline phosphatase
ETAA8_36030	COG0347	Belongs to the P(II) protein family
ETAA8_36080	COG0582	viral genome integration into host DNA
ETAA8_36140	COG1475	DNA binding
ETAA8_36270	COG0446	pyridine nucleotide-disulphide oxidoreductase
ETAA8_36280	COG2226	methyltransferase
ETAA8_36290	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ETAA8_36340	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETAA8_36350	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETAA8_36400	COG3119	arylsulfatase activity
ETAA8_36410	COG0596	Alpha beta hydrolase
ETAA8_36420	COG1942	4-Oxalocrotonate Tautomerase
ETAA8_36440	COG1764	response to oxidative stress
ETAA8_36450	COG1902	pentaerythritol trinitrate reductase activity
ETAA8_36470	COG0563	adenylate kinase activity
ETAA8_36510	COG1233	COG1233 Phytoene dehydrogenase and related
ETAA8_36550	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
ETAA8_36580	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ETAA8_36680	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
ETAA8_36950	COG0303	'Molybdopterin
ETAA8_37000	COG4980	gas vesicle protein
ETAA8_37000	COG1674	ftsk spoiiie
ETAA8_37010	COG0824	Thioesterase
ETAA8_37020	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
ETAA8_37030	COG0573	inorganic phosphate transmembrane transporter activity
ETAA8_37050	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ETAA8_37090	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA8_37100	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ETAA8_37110	COG0750	zinc metalloprotease
ETAA8_37120	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ETAA8_37130	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETAA8_37150	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ETAA8_37170	COG0492	ferredoxin-NADP+ reductase activity
ETAA8_37180	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
ETAA8_37190	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETAA8_37210	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
ETAA8_37260	COG1073	alpha beta
ETAA8_37300	COG5285	phytanoyl-CoA dioxygenase
ETAA8_37350	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ETAA8_37400	COG0848	biopolymer transport protein
ETAA8_37440	COG0148	phosphopyruvate hydratase activity
ETAA8_37450	COG1242	4 iron, 4 sulfur cluster binding
ETAA8_37520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ETAA8_37530	COG4229	Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene)
ETAA8_37540	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ETAA8_37550	COG0235	Class ii aldolase
ETAA8_37590	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ETAA8_37640	COG3119	arylsulfatase activity
ETAA8_37710	COG0668	transmembrane transport
ETAA8_37800	COG0745	RESPONSE REGULATOR receiver
ETAA8_37820	COG1484	DNA-dependent DNA replication
ETAA8_37960	COG1132	(ABC) transporter
ETAA8_37970	COG0583	DNA-binding transcription factor activity
ETAA8_37990	COG1032	radical SAM domain protein
ETAA8_38000	COG0673	inositol 2-dehydrogenase activity
ETAA8_38010	COG1960	acyl-CoA dehydrogenase activity
ETAA8_38030	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ETAA8_38050	COG1162	GTPase activity
ETAA8_38080	COG0134	indole-3-glycerol-phosphate synthase activity
ETAA8_38100	COG0175	sulfate reduction
ETAA8_38110	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ETAA8_38160	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ETAA8_38180	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ETAA8_38190	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ETAA8_38200	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ETAA8_38210	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ETAA8_38220	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ETAA8_38230	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ETAA8_38240	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ETAA8_38250	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ETAA8_38250	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ETAA8_38270	COG0515	serine threonine protein kinase
ETAA8_38270	COG2815	serine threonine protein kinase
ETAA8_38280	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ETAA8_38280	COG0321	lipoyl(octanoyl) transferase activity
ETAA8_38320	COG1234	tRNA 3'-trailer cleavage
ETAA8_38330	COG2183	response to ionizing radiation
ETAA8_38340	COG4191	Histidine kinase
ETAA8_38350	COG4566	intracellular signal transduction
ETAA8_38360	COG0237	dephospho-CoA kinase activity
ETAA8_38370	COG1940	carbohydrate kinase activity
ETAA8_38380	COG0248	Ppx GppA phosphatase
ETAA8_38390	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ETAA8_38400	COG0588	phosphoglycerate mutase activity
ETAA8_38460	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ETAA8_38470	COG2890	protein-(glutamine-N5) methyltransferase activity
ETAA8_38480	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ETAA8_38490	COG0254	rRNA binding
ETAA8_38500	COG0724	RNA recognition motif
ETAA8_38510	COG0154	amidase activity
ETAA8_38550	COG0586	Pfam SNARE associated Golgi protein
ETAA8_38560	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ETAA8_38590	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_38620	COG3850	Histidine kinase
ETAA8_38620	COG3437	response regulator, receiver
ETAA8_38620	COG2205	protein histidine kinase activity
ETAA8_38620	COG4999	Histidine kinase
ETAA8_38630	COG2205	protein histidine kinase activity
ETAA8_38630	COG0784	Response regulator, receiver
ETAA8_38700	COG1012	belongs to the aldehyde dehydrogenase family
ETAA8_38850	COG1450	Type ii and iii secretion system protein
ETAA8_38910	COG2165	general secretion pathway protein
ETAA8_38930	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ETAA8_39000	COG0515	serine threonine protein kinase
ETAA8_39000	COG2815	serine threonine protein kinase
ETAA8_39030	COG3119	arylsulfatase activity
ETAA8_39040	COG3119	arylsulfatase activity
ETAA8_39100	COG1484	DNA-dependent DNA replication
ETAA8_39130	COG3265	gluconokinase activity
ETAA8_39160	COG3119	arylsulfatase activity
ETAA8_39170	COG3119	arylsulfatase activity
ETAA8_39220	COG1484	DNA-dependent DNA replication
ETAA8_39250	COG0515	serine threonine protein kinase
ETAA8_39250	COG2815	serine threonine protein kinase
ETAA8_39390	COG0657	acetylesterase activity
ETAA8_39420	COG3119	arylsulfatase activity
ETAA8_39570	COG1475	DNA binding
ETAA8_39630	COG1525	nuclease
ETAA8_39760	COG3119	arylsulfatase activity
ETAA8_39870	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ETAA8_39880	COG1074	ATP-dependent DNA helicase activity
ETAA8_40010	COG1475	DNA binding
ETAA8_40060	COG1475	DNA binding
ETAA8_40180	COG0745	RESPONSE REGULATOR receiver
ETAA8_40190	COG0643	Histidine kinase
ETAA8_40190	COG2198	Histidine kinase
ETAA8_40230	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ETAA8_40240	COG2201	protein-glutamate methylesterase activity
ETAA8_40250	COG2201	protein-glutamate methylesterase activity
ETAA8_40270	COG0784	Response regulator, receiver
ETAA8_40270	COG2205	protein histidine kinase activity
ETAA8_40290	COG0589	response to stress
ETAA8_40420	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
ETAA8_40450	COG0732	type I restriction modification DNA specificity domain
ETAA8_40460	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
ETAA8_40550	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ETAA8_40660	COG3119	arylsulfatase activity
ETAA8_40690	COG3119	arylsulfatase activity
ETAA8_40700	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETAA8_40730	COG2197	response regulator
ETAA8_40750	COG4585	Histidine kinase
ETAA8_40760	COG0469	pyruvate kinase activity
ETAA8_40770	COG3119	arylsulfatase activity
ETAA8_40800	COG3119	arylsulfatase activity
ETAA8_40840	COG0446	pyridine nucleotide-disulphide oxidoreductase
ETAA8_40910	COG2197	response regulator
ETAA8_40920	COG4585	Histidine kinase
ETAA8_41010	COG0657	acetylesterase activity
ETAA8_41040	COG3119	arylsulfatase activity
ETAA8_41050	COG3119	arylsulfatase activity
ETAA8_41070	COG3119	arylsulfatase activity
ETAA8_41100	COG1335	isochorismatase
ETAA8_41110	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ETAA8_41120	COG1053	succinate dehydrogenase
ETAA8_41120	COG3976	FMN-binding domain protein
ETAA8_41200	COG1073	alpha beta
ETAA8_41230	COG2226	methyltransferase
ETAA8_41280	COG0667	Aldo Keto reductase
ETAA8_41290	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ETAA8_41420	COG3119	arylsulfatase activity
ETAA8_41430	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_41440	COG0596	Alpha beta hydrolase
ETAA8_41470	COG1858	cytochrome C peroxidase
ETAA8_41500	COG3059	membrane
ETAA8_41510	COG2204	response regulator
ETAA8_41550	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ETAA8_41560	COG0702	epimerase
ETAA8_41580	COG2815	serine threonine protein kinase
ETAA8_41580	COG0515	serine threonine protein kinase
ETAA8_41620	COG1484	DNA-dependent DNA replication
ETAA8_41680	COG1959	2 iron, 2 sulfur cluster binding
ETAA8_41680	COG1295	ribonuclease BN
ETAA8_41720	COG2015	COG2015, Alkyl sulfatase and related hydrolases
ETAA8_41730	COG3119	arylsulfatase activity
ETAA8_41770	COG1686	Belongs to the peptidase S11 family
ETAA8_41820	COG0589	response to stress
ETAA8_41890	COG3118	belongs to the thioredoxin family
ETAA8_41920	COG1484	DNA-dependent DNA replication
ETAA8_41950	COG2815	serine threonine protein kinase
ETAA8_41950	COG0515	serine threonine protein kinase
ETAA8_42050	COG1484	DNA-dependent DNA replication
ETAA8_42160	COG0515	serine threonine protein kinase
ETAA8_42160	COG2815	serine threonine protein kinase
ETAA8_42170	COG2124	cytochrome p450
ETAA8_42210	COG0482	sulfurtransferase activity
ETAA8_42220	COG0673	inositol 2-dehydrogenase activity
ETAA8_42250	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ETAA8_42370	COG0811	peptide transport
ETAA8_42380	COG0848	biopolymer transport protein
ETAA8_42470	COG3119	arylsulfatase activity
ETAA8_42480	COG3119	arylsulfatase activity
ETAA8_42490	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ETAA8_42520	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ETAA8_42540	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ETAA8_42570	COG1338	Plays a role in the flagellum-specific transport system
ETAA8_42590	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETAA8_42710	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_42720	COG4864	UPF0365 protein
ETAA8_42740	COG2084	Dehydrogenase
ETAA8_42750	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_42750	COG0515	serine threonine protein kinase
ETAA8_42800	COG1196	nuclear chromosome segregation
ETAA8_42870	COG0714	Associated with various cellular activities
ETAA8_42940	COG0442	prolyl-tRNA aminoacylation
ETAA8_42960	COG1668	transmembrane transport
ETAA8_42970	COG4555	ABC transporter
ETAA8_43000	COG0347	Belongs to the P(II) protein family
ETAA8_43010	COG0004	ammonium transporteR
ETAA8_43030	COG1994	Peptidase M50
ETAA8_43050	COG0714	Associated with various cellular activities
ETAA8_43110	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ETAA8_43140	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ETAA8_43180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ETAA8_43210	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ETAA8_43240	COG3119	arylsulfatase activity
ETAA8_43360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA8_43510	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
ETAA8_43530	COG1477	protein flavinylation
ETAA8_43750	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETAA8_43760	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ETAA8_43770	COG1620	l-lactate permease
ETAA8_43790	COG0574	Belongs to the PEP-utilizing enzyme family
ETAA8_43790	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ETAA8_43810	COG0589	response to stress
ETAA8_43880	COG2197	response regulator
ETAA8_43890	COG0583	DNA-binding transcription factor activity
ETAA8_43940	COG0175	sulfate reduction
ETAA8_43970	COG0583	DNA-binding transcription factor activity
ETAA8_43990	COG0501	Belongs to the peptidase M48B family
ETAA8_44040	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ETAA8_44070	COG1484	DNA-dependent DNA replication
ETAA8_44090	COG0469	pyruvate kinase activity
ETAA8_44110	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ETAA8_44140	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_44160	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ETAA8_44190	COG0702	epimerase
ETAA8_44230	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
ETAA8_44340	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ETAA8_44350	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ETAA8_44360	COG1595	DNA-templated transcription, initiation
ETAA8_44380	COG2080	2 iron, 2 sulfur cluster binding
ETAA8_44390	COG2080	2 iron, 2 sulfur cluster binding
ETAA8_44390	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ETAA8_44420	COG1940	carbohydrate kinase activity
ETAA8_44430	COG0481	GTPase activity
ETAA8_44470	COG2382	esterase
ETAA8_44540	COG2165	general secretion pathway protein
ETAA8_44580	COG2207	Transcriptional regulator
ETAA8_44580	COG1609	Transcriptional regulator
ETAA8_44640	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ETAA8_44650	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_44660	COG1846	Transcriptional regulator
ETAA8_44680	COG0045	succinate-CoA ligase (ADP-forming) activity
ETAA8_44730	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ETAA8_44750	COG1774	PSP1 C-terminal conserved region
ETAA8_44770	COG0528	UMP kinase activity
ETAA8_44790	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ETAA8_44850	COG0552	protein localization to endoplasmic reticulum
ETAA8_44860	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ETAA8_44880	COG1172	Belongs to the binding-protein-dependent transport system permease family
ETAA8_44890	COG1879	ABC-type sugar transport system periplasmic component
ETAA8_44900	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ETAA8_44910	COG0515	serine threonine protein kinase
ETAA8_44930	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ETAA8_44970	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ETAA8_45000	COG0617	tRNA 3'-terminal CCA addition
ETAA8_45130	COG0515	serine threonine protein kinase
ETAA8_45130	COG2815	serine threonine protein kinase
ETAA8_45290	COG2610	gluconate transmembrane transporter activity
ETAA8_45370	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ETAA8_45410	COG2815	serine threonine protein kinase
ETAA8_45410	COG0515	serine threonine protein kinase
ETAA8_45780	COG1073	alpha beta
ETAA8_45830	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ETAA8_45910	COG1484	DNA-dependent DNA replication
ETAA8_45970	COG2045	Belongs to the ComB family
ETAA8_45990	COG0114	fumarate hydratase activity
ETAA8_46010	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETAA8_46060	COG3132	Protein of unknown function, DUF480
ETAA8_46070	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETAA8_46080	COG0017	Asparaginyl-tRNA synthetase
ETAA8_46100	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ETAA8_46320	COG0667	Aldo Keto reductase
ETAA8_46410	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETAA8_46440	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA8_46450	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ETAA8_46460	COG0649	NAD binding
ETAA8_46570	COG4974	Belongs to the 'phage' integrase family
ETAA8_46600	COG2255	four-way junction helicase activity
ETAA8_46760	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETAA8_46880	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ETAA8_46890	COG1484	DNA-dependent DNA replication
ETAA8_46940	COG1139	Iron-sulfur cluster binding protein
ETAA8_46950	COG0277	FAD linked oxidase domain protein
ETAA8_46960	COG0277	FAD linked oxidase domain protein
ETAA8_46970	COG0247	lactate metabolic process
ETAA8_46990	COG0443	Heat shock 70 kDa protein
ETAA8_47000	COG1605	Chorismate mutase
ETAA8_47000	COG0077	Prephenate dehydratase
ETAA8_47010	COG1562	ergosterol biosynthetic process
ETAA8_47080	COG3604	Transcriptional regulator
ETAA8_47090	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
ETAA8_47100	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
ETAA8_47110	COG4208	sulfate ABC transporter
ETAA8_47150	COG2814	Major facilitator Superfamily
ETAA8_47160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ETAA8_47180	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ETAA8_47190	COG1419	protein localization to endoplasmic reticulum
ETAA8_47200	COG2151	metal-sulfur cluster biosynthetic enzyme
ETAA8_47200	COG0489	protein tyrosine kinase activity
ETAA8_47220	COG1191	sigma factor activity
ETAA8_47270	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ETAA8_47280	COG2255	four-way junction helicase activity
ETAA8_47300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_47360	COG0540	Belongs to the ATCase OTCase family
ETAA8_47370	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ETAA8_47380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_47400	COG3119	arylsulfatase activity
ETAA8_47460	COG0824	Thioesterase
ETAA8_47510	COG4401	Chorismate mutase type I
ETAA8_47570	COG0384	phenazine biosynthesis protein PhzF
ETAA8_47600	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
ETAA8_47610	COG0657	acetylesterase activity
ETAA8_47640	COG0515	serine threonine protein kinase
ETAA8_47640	COG2815	serine threonine protein kinase
ETAA8_47650	COG0459	protein refolding
ETAA8_47660	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ETAA8_47670	COG0459	protein refolding
ETAA8_47680	COG0484	heat shock protein binding
ETAA8_47690	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ETAA8_47710	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ETAA8_47760	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_47790	COG1404	Belongs to the peptidase S8 family
ETAA8_47830	COG2020	methyltransferase activity
ETAA8_47840	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ETAA8_47860	COG0363	glucosamine-6-phosphate deaminase activity
ETAA8_47880	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_47890	COG1764	response to oxidative stress
ETAA8_47900	COG0546	phosphoglycolate phosphatase activity
ETAA8_47910	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETAA8_47920	COG0402	S-adenosylhomocysteine deaminase activity
ETAA8_47930	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ETAA8_47940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETAA8_47960	COG4864	UPF0365 protein
ETAA8_47990	COG0386	Belongs to the glutathione peroxidase family
ETAA8_48000	COG0047	phosphoribosylformylglycinamidine synthase activity
ETAA8_48050	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ETAA8_48080	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETAA8_48100	COG0107	imidazoleglycerol-phosphate synthase activity
ETAA8_48140	COG0793	Belongs to the peptidase S41A family
ETAA8_48150	COG0799	negative regulation of ribosome biogenesis
ETAA8_48160	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ETAA8_48160	COG0758	DNA mediated transformation
ETAA8_48170	COG4566	intracellular signal transduction
ETAA8_48180	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ETAA8_48210	COG0018	arginyl-trna synthetase
ETAA8_48310	COG1129	ABC transporter
ETAA8_48320	COG4214	carbohydrate transport
ETAA8_48430	COG0714	Associated with various cellular activities
ETAA8_48480	COG0138	bifunctional purine biosynthesis protein purh
ETAA8_48550	COG0590	tRNA wobble adenosine to inosine editing
ETAA8_48560	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ETAA8_48570	COG1012	belongs to the aldehyde dehydrogenase family
ETAA8_48600	COG1953	Uracil, thiamine, allantoin
ETAA8_48610	COG0167	dihydroorotate dehydrogenase activity
ETAA8_48610	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
ETAA8_48620	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ETAA8_48660	COG1335	isochorismatase
ETAA8_48710	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ETAA8_48770	COG4968	Prepilin-type N-terminal cleavage methylation domain
ETAA8_48800	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ETAA8_48880	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ETAA8_48910	COG0561	phosphatase activity
ETAA8_48940	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ETAA8_48950	COG0228	four-way junction DNA binding
ETAA8_48960	COG0336	Belongs to the RNA methyltransferase TrmD family
ETAA8_48970	COG0335	large ribosomal subunit rRNA binding
ETAA8_48980	COG0792	nuclease activity
ETAA8_49070	COG0681	Belongs to the peptidase S26 family
ETAA8_49080	COG1137	ATPase activity
ETAA8_49090	COG0745	RESPONSE REGULATOR receiver
ETAA8_49100	COG1408	metallophosphoesterase
ETAA8_49110	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETAA8_49170	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ETAA8_49190	COG1063	alcohol dehydrogenase
ETAA8_49210	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ETAA8_49230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_49240	COG0456	acetyltransferase
ETAA8_49240	COG0454	-acetyltransferase
ETAA8_49260	COG2816	NAD+ diphosphatase activity
ETAA8_49310	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ETAA8_49320	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ETAA8_49330	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ETAA8_49350	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ETAA8_49380	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ETAA8_49380	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ETAA8_49430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_49460	COG1132	(ABC) transporter
ETAA8_49480	COG0714	Associated with various cellular activities
ETAA8_49620	COG0667	Aldo Keto reductase
ETAA8_49640	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ETAA8_49660	COG0473	3-isopropylmalate dehydrogenase activity
ETAA8_49770	COG0673	inositol 2-dehydrogenase activity
ETAA8_49830	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ETAA8_49860	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ETAA8_49880	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ETAA8_49930	COG2258	MOSC domain
ETAA8_49940	COG1160	GTP binding
ETAA8_49960	COG2059	Chromate
ETAA8_50140	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETAA8_50150	COG3119	arylsulfatase activity
ETAA8_50170	COG0714	Associated with various cellular activities
ETAA8_50180	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ETAA8_50190	COG0305	Participates in initiation and elongation during chromosome replication
ETAA8_50200	COG0359	binds to the 23S rRNA
ETAA8_50210	COG0629	single-stranded DNA binding
ETAA8_50220	COG0360	Binds together with S18 to 16S ribosomal RNA
ETAA8_50230	COG0193	aminoacyl-tRNA hydrolase activity
ETAA8_50240	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ETAA8_50290	COG2755	lipolytic protein G-D-S-L family
ETAA8_50310	COG1217	gtp-binding protein TYPA
ETAA8_50340	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ETAA8_50350	COG0328	RNA-DNA hybrid ribonuclease activity
ETAA8_50360	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ETAA8_50380	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ETAA8_50410	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_50420	COG1331	Highly conserved protein containing a thioredoxin domain
ETAA8_50430	COG3193	protein, possibly involved in utilization of glycolate and propanediol
ETAA8_50480	COG0203	ribosomal protein L17
ETAA8_50490	COG0202	RNA polymerase activity
ETAA8_50500	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ETAA8_50510	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ETAA8_50530	COG0343	queuine tRNA-ribosyltransferase activity
ETAA8_50640	COG0704	Plays a role in the regulation of phosphate uptake
ETAA8_50670	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ETAA8_50680	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ETAA8_50700	COG4869	propanediol catabolic process
ETAA8_50720	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ETAA8_50730	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ETAA8_50740	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
ETAA8_50760	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
ETAA8_50800	COG0039	L-malate dehydrogenase activity
ETAA8_50810	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ETAA8_50830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ETAA8_50900	COG3119	arylsulfatase activity
ETAA8_50920	COG0328	RNA-DNA hybrid ribonuclease activity
ETAA8_50950	COG0181	hydroxymethylbilane synthase activity
ETAA8_50970	COG2239	Acts as a magnesium transporter
ETAA8_50990	COG1132	(ABC) transporter
ETAA8_51040	COG0420	3'-5' exonuclease activity
ETAA8_51050	COG4717	serine-type aminopeptidase activity
ETAA8_51070	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_51080	COG0515	serine threonine protein kinase
ETAA8_51150	COG1891	lyase activity
ETAA8_51180	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ETAA8_51180	COG4797	methyltransferase
ETAA8_51190	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_51210	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ETAA8_51270	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ETAA8_51300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ETAA8_51320	COG0489	protein tyrosine kinase activity
ETAA8_51380	COG1702	phosphate starvation-inducible protein PhoH
ETAA8_51390	COG1480	7TM receptor with intracellular HD hydrolase
ETAA8_51400	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ETAA8_51530	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_51540	COG0788	formyltetrahydrofolate deformylase activity
ETAA8_51550	COG0154	amidase activity
ETAA8_51560	COG0584	glycerophosphoryl diester phosphodiesterase
ETAA8_51610	COG0464	growth
ETAA8_51640	COG0745	RESPONSE REGULATOR receiver
ETAA8_51650	COG5002	protein histidine kinase activity
ETAA8_51700	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETAA8_51750	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ETAA8_51770	COG2165	general secretion pathway protein
ETAA8_51780	COG1573	uracil-dna glycosylase
ETAA8_51790	COG0693	protein deglycase activity
ETAA8_51870	COG2124	cytochrome p450
ETAA8_51880	COG2081	HI0933 family
ETAA8_51920	COG0066	3-isopropylmalate dehydratase activity
ETAA8_51930	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ETAA8_51980	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ETAA8_52030	COG2326	polyphosphate kinase activity
ETAA8_52050	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ETAA8_52060	COG2308	Evidence 4 Homologs of previously reported genes of
ETAA8_52090	COG1305	Transglutaminase-like
ETAA8_52170	COG0826	peptidase U32
ETAA8_52180	COG4191	Histidine kinase
ETAA8_52190	COG1185	polyribonucleotide nucleotidyltransferase activity
ETAA8_52200	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ETAA8_52210	COG1418	mRNA catabolic process
ETAA8_52360	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ETAA8_52460	COG0434	BtpA family
ETAA8_52560	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ETAA8_52570	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ETAA8_52580	COG0149	triose-phosphate isomerase activity
ETAA8_52600	COG1561	YicC-like family, N-terminal region
ETAA8_52610	COG0194	GDP metabolic process
ETAA8_52620	COG1758	RNA polymerase activity
ETAA8_52630	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ETAA8_52660	COG1104	cysteine desulfurase activity
ETAA8_52690	COG2226	methyltransferase
ETAA8_52700	COG1606	tRNA processing
ETAA8_52710	COG0842	Transport permease protein
ETAA8_52710	COG1129	ABC transporter
ETAA8_52720	COG1131	(ABC) transporter
ETAA8_52750	COG0515	serine threonine protein kinase
ETAA8_52750	COG2815	serine threonine protein kinase
ETAA8_52770	COG3119	arylsulfatase activity
ETAA8_52780	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETAA8_52820	COG1609	Transcriptional regulator
ETAA8_52860	COG0628	permease
ETAA8_52880	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ETAA8_52890	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ETAA8_52960	COG0714	Associated with various cellular activities
ETAA8_53050	COG2088	sporulation resulting in formation of a cellular spore
ETAA8_53060	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ETAA8_53080	COG0657	acetylesterase activity
ETAA8_53080	COG2755	lipolytic protein G-D-S-L family
ETAA8_53100	COG4968	Prepilin-type N-terminal cleavage methylation domain
ETAA8_53120	COG4968	Prepilin-type N-terminal cleavage methylation domain
ETAA8_53140	COG2165	general secretion pathway protein
ETAA8_53230	COG2204	response regulator
ETAA8_53250	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
ETAA8_53270	COG1104	cysteine desulfurase activity
ETAA8_53340	COG1404	Belongs to the peptidase S8 family
ETAA8_53360	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ETAA8_53390	COG1321	iron dependent repressor
ETAA8_53410	COG2204	response regulator
ETAA8_53420	COG2197	response regulator
ETAA8_53430	COG4974	Belongs to the 'phage' integrase family
ETAA8_53530	COG1639	'signal transduction protein
ETAA8_53570	COG3119	arylsulfatase activity
ETAA8_53600	COG4948	Mandelate Racemase Muconate Lactonizing
ETAA8_53610	COG4948	Mandelate Racemase Muconate Lactonizing
ETAA8_53630	COG1477	protein flavinylation
ETAA8_53640	COG0445	tRNA wobble uridine modification
ETAA8_53690	COG0523	cobalamin synthesis protein
ETAA8_53710	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ETAA8_53750	COG0714	Associated with various cellular activities
ETAA8_53820	COG0277	FAD linked oxidase domain protein
ETAA8_53950	COG4149	molybdate abc transporter
ETAA8_53960	COG0725	ABC transporter, periplasmic molybdate-binding protein
ETAA8_54180	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETAA8_54200	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ETAA8_54210	COG0072	phenylalanine-tRNA ligase activity
ETAA8_54220	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ETAA8_54230	COG0473	3-isopropylmalate dehydrogenase activity
ETAA8_54230	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ETAA8_54250	COG0372	Belongs to the citrate synthase family
ETAA8_54260	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ETAA8_54270	COG0602	queuosine metabolic process
ETAA8_54280	COG5002	protein histidine kinase activity
ETAA8_54310	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETAA8_54320	COG1459	type II secretion system
ETAA8_54340	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ETAA8_54390	COG0724	RNA recognition motif
ETAA8_54420	COG0142	geranyltranstransferase activity
ETAA8_54440	COG2814	Major facilitator Superfamily
ETAA8_54450	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ETAA8_54450	COG0519	Catalyzes the synthesis of GMP from XMP
ETAA8_54490	COG4122	O-methyltransferase activity
ETAA8_54590	COG3119	arylsulfatase activity
ETAA8_54660	COG2226	methyltransferase
ETAA8_54670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_54690	COG0673	inositol 2-dehydrogenase activity
ETAA8_54700	COG1063	alcohol dehydrogenase
ETAA8_54710	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ETAA8_54720	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ETAA8_54730	COG0131	Imidazoleglycerol-phosphate dehydratase
ETAA8_54750	COG0205	6-phosphofructokinase activity
ETAA8_54760	COG0793	Belongs to the peptidase S41A family
ETAA8_54770	COG0009	L-threonylcarbamoyladenylate synthase
ETAA8_54930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ETAA8_54940	COG1166	arginine decarboxylase activity
ETAA8_55000	COG0793	Belongs to the peptidase S41A family
ETAA8_55010	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ETAA8_55040	COG0537	adenosine 5'-monophosphoramidase activity
ETAA8_55050	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETAA8_55060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETAA8_55070	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETAA8_55080	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ETAA8_55270	COG0300	oxidoreductase activity
ETAA8_55370	COG0544	peptidyl-prolyl cis-trans isomerase activity
ETAA8_55380	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_55390	COG0495	leucyl-tRNA aminoacylation
ETAA8_55440	COG4566	intracellular signal transduction
ETAA8_55450	COG4191	Histidine kinase
ETAA8_55460	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
ETAA8_55520	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ETAA8_55530	COG0166	Belongs to the GPI family
ETAA8_55540	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
ETAA8_55560	COG0011	TIGRFAM Protein of
ETAA8_55570	COG0579	oxidoreductase
ETAA8_55580	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
ETAA8_55590	COG0686	Belongs to the AlaDH PNT family
ETAA8_55750	COG3781	membrane
ETAA8_55790	COG3852	Histidine kinase
ETAA8_55820	COG3852	Histidine kinase
ETAA8_55870	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ETAA8_55890	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_55970	COG0563	adenylate kinase activity
ETAA8_55980	COG0201	protein transport
ETAA8_55990	COG0200	Binds to the 23S rRNA
ETAA8_56000	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ETAA8_56010	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ETAA8_56020	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ETAA8_56030	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ETAA8_56040	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ETAA8_56050	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ETAA8_56060	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ETAA8_56070	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ETAA8_56080	COG0255	Belongs to the universal ribosomal protein uL29 family
ETAA8_56090	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ETAA8_56100	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ETAA8_56110	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ETAA8_56120	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ETAA8_56130	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ETAA8_56140	COG0089	rRNA binding
ETAA8_56150	COG0088	Forms part of the polypeptide exit tunnel
ETAA8_56160	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ETAA8_56170	COG0051	transcription antitermination factor activity, RNA binding
ETAA8_56220	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ETAA8_56240	COG0154	amidase activity
ETAA8_56260	COG0723	plastoquinol--plastocyanin reductase activity
ETAA8_56260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETAA8_56290	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETAA8_56410	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ETAA8_56440	COG0250	Participates in transcription elongation, termination and antitermination
ETAA8_56450	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ETAA8_56460	COG0081	regulation of translation
ETAA8_56470	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ETAA8_56490	COG0085	RNA polymerase activity
ETAA8_56500	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ETAA8_56510	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ETAA8_56520	COG0049	tRNA binding
ETAA8_56530	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ETAA8_56550	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_56560	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ETAA8_56600	COG0302	gtp cyclohydrolase
ETAA8_56630	COG0247	lactate metabolic process
ETAA8_56630	COG0277	FAD linked oxidase domain protein
ETAA8_56650	COG0314	molybdopterin synthase activity
ETAA8_56660	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ETAA8_56670	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETAA8_56750	COG0202	RNA polymerase activity
ETAA8_56780	COG3119	arylsulfatase activity
ETAA8_56780	COG3408	Glycogen debranching enzyme
ETAA8_56800	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ETAA8_56870	COG0646	methionine synthase
ETAA8_56870	COG1410	methionine synthase
ETAA8_56880	COG0861	Integral membrane protein TerC family
ETAA8_56920	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ETAA8_56930	COG0515	serine threonine protein kinase
ETAA8_56930	COG2815	serine threonine protein kinase
ETAA8_57030	COG1301	dicarboxylic acid transport
ETAA8_57140	COG0835	chemotaxis
ETAA8_57170	COG2198	Histidine kinase
ETAA8_57170	COG0643	Histidine kinase
ETAA8_57190	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ETAA8_57200	COG2201	protein-glutamate methylesterase activity
ETAA8_57210	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETAA8_57220	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ETAA8_57220	COG4651	solute:proton antiporter activity
ETAA8_57270	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ETAA8_57330	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETAA8_57330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ETAA8_57330	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
ETAA8_57340	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ETAA8_57510	COG0606	chelatase, subunit chli
ETAA8_57530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ETAA8_57550	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ETAA8_57620	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_57630	COG1595	DNA-templated transcription, initiation
ETAA8_57750	COG0179	Fumarylacetoacetate (FAA) hydrolase
ETAA8_58030	COG2204	response regulator
ETAA8_58060	COG0515	serine threonine protein kinase
ETAA8_58060	COG2815	serine threonine protein kinase
ETAA8_58100	COG2197	response regulator
ETAA8_58130	COG1136	(ABC) transporter
ETAA8_58220	COG0459	protein refolding
ETAA8_58410	COG1475	DNA binding
ETAA8_58420	COG1192	Involved in chromosome partitioning
ETAA8_58480	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ETAA8_58500	COG0135	phosphoribosylanthranilate isomerase activity
ETAA8_58550	COG3409	Peptidoglycan-binding domain 1 protein
ETAA8_58550	COG3267	Type II secretory pathway component ExeA
ETAA8_58580	COG1216	Glycosyl transferase, family 2
ETAA8_58600	COG1477	protein flavinylation
ETAA8_58640	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ETAA8_58670	COG0513	Belongs to the DEAD box helicase family
ETAA8_58690	COG5002	protein histidine kinase activity
ETAA8_58700	COG0135	phosphoribosylanthranilate isomerase activity
ETAA8_58710	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
ETAA8_58720	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_58770	COG1678	Uncharacterized ACR, COG1678
ETAA8_58780	COG0583	DNA-binding transcription factor activity
ETAA8_58790	COG0753	catalase activity
ETAA8_58850	COG1262	PFAM Formylglycine-generating sulfatase enzyme
ETAA8_58860	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ETAA8_58900	COG1012	belongs to the aldehyde dehydrogenase family
ETAA8_58910	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ETAA8_58940	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ETAA8_59010	COG1192	Involved in chromosome partitioning
ETAA8_59070	COG2957	Belongs to the agmatine deiminase family
ETAA8_59100	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ETAA8_59130	COG0439	Biotin carboxylase
ETAA8_59140	COG0511	ligase activity, forming carbon-carbon bonds
ETAA8_59170	COG1940	carbohydrate kinase activity
ETAA8_59180	COG1446	asparaginase
ETAA8_59190	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ETAA8_59240	COG1484	DNA-dependent DNA replication
ETAA8_59280	COG3604	Transcriptional regulator
ETAA8_59590	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ETAA8_59760	COG5507	3-demethylubiquinone-9 3-methyltransferase
ETAA8_59850	COG3311	Transcriptional regulator
ETAA8_59860	COG1569	PIN domain
ETAA8_59870	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ETAA8_59890	COG0859	PFAM glycosyl transferase family 9
ETAA8_59900	COG4786	Flagellar basal body rod
ETAA8_59910	COG4786	Flagellar basal body rod
ETAA8_59930	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ETAA8_59940	COG1706	bacterial-type flagellum-dependent cell motility
ETAA8_60000	COG0811	peptide transport
ETAA8_60030	COG0358	DNA primase activity
ETAA8_60040	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETAA8_60070	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ETAA8_60100	COG0191	fructose-bisphosphate aldolase activity
ETAA8_60110	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ETAA8_60140	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
ETAA8_60190	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_60230	COG2815	serine threonine protein kinase
ETAA8_60230	COG0515	serine threonine protein kinase
ETAA8_60250	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETAA8_60270	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ETAA8_60280	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETAA8_60300	COG0318	PFAM AMP-dependent synthetase and ligase
ETAA8_60380	COG0674	pyruvate-flavodoxin oxidoreductase activity
ETAA8_60380	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ETAA8_60390	COG1013	pyruvate-flavodoxin oxidoreductase activity
ETAA8_60440	COG0519	Catalyzes the synthesis of GMP from XMP
ETAA8_60480	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ETAA8_60490	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ETAA8_60520	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ETAA8_60550	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ETAA8_60560	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ETAA8_60680	COG3781	membrane
ETAA8_60700	COG0583	DNA-binding transcription factor activity
ETAA8_60710	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ETAA8_60750	COG2706	6-phosphogluconolactonase activity
ETAA8_60790	COG0405	Gamma-glutamyltransferase
ETAA8_60840	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ETAA8_60850	COG0242	peptide deformylase activity
ETAA8_60900	COG0747	negative chemotaxis
ETAA8_60910	COG0601	transmembrane transport
ETAA8_60920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETAA8_60950	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ETAA8_60960	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_60980	COG4964	Belongs to the GSP D family
ETAA8_61120	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ETAA8_61160	COG2204	response regulator
ETAA8_61170	COG3852	Histidine kinase
ETAA8_61180	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ETAA8_61200	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
ETAA8_61210	COG3119	arylsulfatase activity
ETAA8_61280	COG0714	Associated with various cellular activities
ETAA8_61290	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ETAA8_61300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ETAA8_61350	COG2135	peptidase activity
ETAA8_61360	COG1012	belongs to the aldehyde dehydrogenase family
ETAA8_61370	COG1295	ribonuclease BN
ETAA8_61380	COG1760	l-serine dehydratase
ETAA8_61400	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ETAA8_61450	COG1132	(ABC) transporter
ETAA8_61470	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ETAA8_61480	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ETAA8_61510	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ETAA8_61520	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ETAA8_61530	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ETAA8_61590	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ETAA8_61630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ETAA8_61670	COG0640	Transcriptional regulator
ETAA8_61970	COG0724	RNA recognition motif
ETAA8_62030	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_62070	COG1960	acyl-CoA dehydrogenase activity
ETAA8_62210	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETAA8_62250	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ETAA8_62290	COG1657	PFAM Prenyltransferase squalene oxidase
ETAA8_62300	COG0322	excinuclease ABC activity
ETAA8_62340	COG1301	dicarboxylic acid transport
ETAA8_62390	COG1201	RNA secondary structure unwinding
ETAA8_62440	COG0142	geranyltranstransferase activity
ETAA8_62460	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ETAA8_62480	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ETAA8_62560	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ETAA8_62590	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ETAA8_62600	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ETAA8_62650	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ETAA8_62680	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ETAA8_62680	COG1918	ferrous iron import across plasma membrane
ETAA8_62710	COG0673	inositol 2-dehydrogenase activity
ETAA8_62750	COG1132	(ABC) transporter
ETAA8_62770	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ETAA8_62910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ETAA8_63060	COG1191	sigma factor activity
ETAA8_63110	COG2353	YceI-like domain
ETAA8_63130	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ETAA8_63140	COG0575	Belongs to the CDS family
ETAA8_63250	COG1921	L-seryl-tRNASec selenium transferase activity
ETAA8_63340	COG4555	ABC transporter
ETAA8_63380	COG0714	Associated with various cellular activities
ETAA8_63400	COG0471	metal ion transport
ETAA8_63400	COG3273	potassium ion transport
ETAA8_63440	COG0297	glycogen (starch) synthase activity
ETAA8_63500	COG2271	Major facilitator Superfamily
ETAA8_63680	COG1070	Carbohydrate kinase
ETAA8_63780	COG1663	tetraacyldisaccharide 4'-kinase activity
ETAA8_63800	COG0529	Catalyzes the synthesis of activated sulfate
ETAA8_63940	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ETAA8_63950	COG0667	Aldo Keto reductase
ETAA8_64040	COG1459	type II secretion system
ETAA8_64050	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETAA8_64070	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ETAA8_64100	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ETAA8_64110	COG1858	cytochrome C peroxidase
ETAA8_64130	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ETAA8_64170	COG2115	Belongs to the xylose isomerase family
ETAA8_64180	COG4585	Histidine kinase
ETAA8_64200	COG1181	Belongs to the D-alanine--D-alanine ligase family
ETAA8_64210	COG1181	Belongs to the D-alanine--D-alanine ligase family
ETAA8_64310	COG0564	pseudouridine synthase activity
ETAA8_64340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_64360	COG0673	inositol 2-dehydrogenase activity
ETAA8_64420	COG0475	glutathione-regulated potassium exporter activity
ETAA8_64450	COG0811	peptide transport
ETAA8_64540	COG0673	inositol 2-dehydrogenase activity
ETAA8_64570	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ETAA8_64580	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ETAA8_64590	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ETAA8_64610	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ETAA8_64630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ETAA8_64680	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ETAA8_64700	COG0631	protein serine/threonine phosphatase activity
ETAA8_64710	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ETAA8_64720	COG4566	intracellular signal transduction
ETAA8_64840	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
ETAA8_64860	COG4956	integral membrane protein (PIN domain superfamily)
ETAA8_64870	COG3706	GGDEF domain
ETAA8_65000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA8_65150	COG2226	methyltransferase
ETAA8_65240	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ETAA8_65300	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA8_65310	COG1484	DNA-dependent DNA replication
ETAA8_65420	COG3335	DDE superfamily endonuclease
ETAA8_65430	COG2204	response regulator
ETAA8_65460	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
ETAA8_65470	COG4251	negative regulation of phosphorylation
ETAA8_65480	COG4251	negative regulation of phosphorylation
ETAA8_65490	COG0784	Response regulator, receiver
ETAA8_65490	COG2205	protein histidine kinase activity
ETAA8_65590	COG2815	serine threonine protein kinase
ETAA8_65590	COG0515	serine threonine protein kinase
ETAA8_65600	COG0515	serine threonine protein kinase
ETAA8_65600	COG2815	serine threonine protein kinase
ETAA8_65610	COG3119	arylsulfatase activity
ETAA8_65640	COG3119	arylsulfatase activity
ETAA8_65700	COG0105	UTP biosynthetic process
ETAA8_65710	COG0156	8-amino-7-oxononanoate synthase activity
ETAA8_65800	COG0640	Transcriptional regulator
ETAA8_65810	COG2154	pterin-4-alpha-carbinolamine dehydratase
ETAA8_65820	COG4221	oxidoreductase activity
ETAA8_65910	COG1643	Atp-dependent helicase
ETAA8_65960	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ETAA8_66050	COG0504	CTP synthase activity
ETAA8_66110	COG0531	amino acid
ETAA8_66140	COG0450	alkyl hydroperoxide reductase
ETAA8_66280	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ETAA8_66290	COG0542	response to heat
ETAA8_66300	COG3869	Catalyzes the specific phosphorylation of arginine residues in
ETAA8_66310	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ETAA8_66320	COG0215	cysteine-tRNA ligase activity
ETAA8_66330	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ETAA8_66340	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ETAA8_66350	COG0800	Aldolase
ETAA8_66380	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ETAA8_66420	COG0012	GTP binding
ETAA8_66470	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ETAA8_66480	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ETAA8_66500	COG0306	phosphate transporter
ETAA8_66510	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ETAA8_66520	COG4948	Mandelate Racemase Muconate Lactonizing
ETAA8_66570	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
ETAA8_66580	COG0431	NADPH-dependent FMN reductase
ETAA8_66590	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ETAA8_66620	COG1073	alpha beta
ETAA8_66640	COG2205	protein histidine kinase activity
ETAA8_66640	COG0784	Response regulator, receiver
ETAA8_66700	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ETAA8_66730	COG0494	nUDIX hydrolase
ETAA8_66740	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ETAA8_66760	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ETAA8_66770	COG1611	Belongs to the LOG family
ETAA8_66800	COG4999	Histidine kinase
ETAA8_66800	COG3850	Histidine kinase
ETAA8_66800	COG3437	response regulator, receiver
ETAA8_66800	COG2205	protein histidine kinase activity
ETAA8_66830	COG0484	heat shock protein binding
ETAA8_66900	COG0129	dihydroxy-acid dehydratase activity
ETAA8_66920	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ETAA8_66940	COG0443	Heat shock 70 kDa protein
ETAA8_66950	COG3119	arylsulfatase activity
ETAA8_66990	COG0179	Fumarylacetoacetate (FAA) hydrolase
ETAA8_67140	COG0778	Nitroreductase
ETAA8_67150	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ETAA8_67160	COG0424	maF-like protein
ETAA8_67170	COG0564	pseudouridine synthase activity
ETAA8_67300	COG5002	protein histidine kinase activity
ETAA8_67340	COG0668	transmembrane transport
ETAA8_67410	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETAA8_67500	COG1231	oxidoreductase activity
ETAA8_67540	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ETAA8_67550	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETAA8_67550	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ETAA8_67570	COG0095	Lipoate-protein ligase
ETAA8_67580	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ETAA8_67590	COG1506	peptidase
ETAA8_67590	COG0823	Involved in the tonB-independent uptake of proteins
ETAA8_67590	COG4946	Tricorn protease homolog
ETAA8_67610	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ETAA8_67620	COG2721	sulfolactate sulfo-lyase activity
ETAA8_67660	COG1228	amidohydrolase
ETAA8_67670	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ETAA8_67710	COG1030	water channel activity
ETAA8_67730	COG1131	(ABC) transporter
ETAA8_67750	COG0037	tRNA processing
ETAA8_67800	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ETAA8_67820	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_67830	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_67860	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
ETAA8_67920	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ETAA8_67930	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ETAA8_67950	COG0109	protoheme IX farnesyltransferase activity
ETAA8_67960	COG1845	cytochrome c oxidase, subunit III
ETAA8_67990	COG2322	membrane
ETAA8_68240	COG0513	Belongs to the DEAD box helicase family
ETAA8_68250	COG1073	alpha beta
ETAA8_68270	COG1278	Cold shock
ETAA8_68290	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ETAA8_68300	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
ETAA8_68390	COG0784	Response regulator, receiver
ETAA8_68390	COG2205	protein histidine kinase activity
ETAA8_68460	COG0596	Alpha beta hydrolase
ETAA8_68610	COG3119	arylsulfatase activity
ETAA8_68620	COG3119	arylsulfatase activity
ETAA8_68630	COG3119	arylsulfatase activity
ETAA8_68670	COG1335	isochorismatase
ETAA8_68680	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
ETAA8_68720	COG3119	arylsulfatase activity
ETAA8_68780	COG0653	protein targeting
ETAA8_68800	COG1595	DNA-templated transcription, initiation
ETAA8_68860	COG1028	Short-chain dehydrogenase reductase Sdr
ETAA8_68900	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ETAA8_68930	COG0583	DNA-binding transcription factor activity
ETAA8_68940	COG0067	glutamate synthase
ETAA8_68940	COG0070	glutamate synthase
ETAA8_68940	COG0069	glutamate synthase activity
ETAA8_68950	COG0493	'glutamate synthase
ETAA8_68960	COG2912	Transglutaminase-like superfamily
ETAA8_69030	COG1959	2 iron, 2 sulfur cluster binding
ETAA8_69050	COG2204	response regulator
ETAA8_69070	COG3852	Histidine kinase
ETAA8_69080	COG0745	RESPONSE REGULATOR receiver
ETAA8_69130	COG2304	oxidoreductase activity
ETAA8_69200	COG0584	glycerophosphoryl diester phosphodiesterase
ETAA8_69210	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ETAA8_69230	COG2195	Cleaves the N-terminal amino acid of tripeptides
ETAA8_69240	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
ETAA8_69250	COG0490	domain, Protein
ETAA8_69250	COG0471	metal ion transport
ETAA8_69290	COG2066	Belongs to the glutaminase family
ETAA8_69350	COG0515	serine threonine protein kinase
ETAA8_69350	COG2815	serine threonine protein kinase
ETAA8_69380	COG0670	Belongs to the BI1 family
ETAA8_69420	COG0179	Fumarylacetoacetate (FAA) hydrolase
ETAA8_69430	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ETAA8_69450	COG4206	TonB-dependent receptor
ETAA8_69470	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ETAA8_69600	COG2333	competence protein COMEC
ETAA8_69600	COG0658	competence protein
ETAA8_69680	COG0730	response to heat
ETAA8_69730	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
ETAA8_69730	COG1796	DNA polymerase
ETAA8_69830	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ETAA8_69830	COG0662	Cupin 2, conserved barrel domain protein
ETAA8_69860	COG4172	Belongs to the ABC transporter superfamily
ETAA8_69870	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ETAA8_69880	COG0601	transmembrane transport
ETAA8_69900	COG0515	serine threonine protein kinase
ETAA8_69900	COG2815	serine threonine protein kinase
ETAA8_69940	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ETAA8_69950	COG0673	inositol 2-dehydrogenase activity
ETAA8_69990	COG0673	inositol 2-dehydrogenase activity
ETAA8_70000	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ETAA8_70010	COG2204	response regulator
ETAA8_70050	COG0745	RESPONSE REGULATOR receiver
ETAA8_70090	COG0529	Catalyzes the synthesis of activated sulfate
ETAA8_70090	COG2895	sulfate adenylyltransferase (ATP) activity
ETAA8_70110	COG0175	sulfate reduction
ETAA8_70140	COG0673	inositol 2-dehydrogenase activity
ETAA8_70150	COG1136	(ABC) transporter
ETAA8_70160	COG0577	efflux transmembrane transporter activity
ETAA8_70160	COG1136	(ABC) transporter
ETAA8_70190	COG0246	Mannitol dehydrogenase
ETAA8_70200	COG1063	alcohol dehydrogenase
ETAA8_70230	COG0673	inositol 2-dehydrogenase activity
ETAA8_70420	COG3842	ATPase activity
ETAA8_70470	COG2027	D-alanyl-D-alanine carboxypeptidase
ETAA8_70560	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ETAA8_70630	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
ETAA8_70650	COG2912	Transglutaminase-like superfamily
ETAA8_70700	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ETAA8_70790	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ETAA8_70820	COG0632	four-way junction helicase activity
ETAA8_70840	COG5492	domain, Protein
ETAA8_70870	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ETAA8_70890	COG1902	pentaerythritol trinitrate reductase activity
ETAA8_70930	COG4974	Belongs to the 'phage' integrase family
ETAA8_70940	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ETAA8_70960	COG1674	ftsk spoiiie
ETAA8_70970	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
ETAA8_70980	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ETAA8_70980	COG1333	cytochrome c biogenesis protein
ETAA8_71010	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ETAA8_71030	COG0463	Glycosyl transferase, family 2
ETAA8_71060	COG0494	nUDIX hydrolase
ETAA8_71120	COG0557	exoribonuclease II activity
ETAA8_71140	COG1131	(ABC) transporter
ETAA8_71220	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ETAA8_71250	COG2442	InterPro IPR007367
ETAA8_71300	COG4717	serine-type aminopeptidase activity