locus-tag	class	description
K9D25_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
K9D25_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
K9D25_00035	COG0028	Belongs to the TPP enzyme family
K9D25_00050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K9D25_00060	COG1999	signal sequence binding
K9D25_00070	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K9D25_00090	COG0513	Belongs to the DEAD box helicase family
K9D25_00100	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9D25_00110	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9D25_00135	COG1131	(ABC) transporter
K9D25_00165	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K9D25_00185	COG0488	(ABC) transporter
K9D25_00225	COG0281	malic enzyme
K9D25_00245	COG1215	transferase activity, transferring glycosyl groups
K9D25_00265	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9D25_00270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9D25_00275	COG1012	belongs to the aldehyde dehydrogenase family
K9D25_00280	COG1177	transmembrane transport
K9D25_00285	COG1176	ABC-type spermidine putrescine transport system, permease component I
K9D25_00290	COG3842	ATPase activity
K9D25_00295	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
K9D25_00315	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
K9D25_00320	COG0667	Aldo Keto reductase
K9D25_00335	COG0318	PFAM AMP-dependent synthetase and ligase
K9D25_00340	COG1268	BioY protein
K9D25_00345	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
K9D25_00350	COG1122	ATPase activity
K9D25_00355	COG1309	transcriptional regulator
K9D25_00365	COG0656	L-ascorbic acid biosynthetic process
K9D25_00390	COG4691	Plasmid stability protein
K9D25_00400	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
K9D25_00435	COG1937	Protein conserved in bacteria
K9D25_00440	COG1280	lysine exporter protein (LysE YggA)
K9D25_00445	COG0318	PFAM AMP-dependent synthetase and ligase
K9D25_00450	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
K9D25_00450	COG4124	Belongs to the glycosyl hydrolase 26 family
K9D25_00460	COG2723	6-phospho-beta-galactosidase activity
K9D25_00475	COG0583	DNA-binding transcription factor activity
K9D25_00480	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9D25_00485	COG4311	Sarcosine oxidase, delta subunit
K9D25_00490	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K9D25_00490	COG0446	pyridine nucleotide-disulphide oxidoreductase
K9D25_00505	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
K9D25_00510	COG0277	FAD linked oxidase domain protein
K9D25_00525	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K9D25_00530	COG2218	PFAM glutamate synthase alpha subunit domain protein
K9D25_00535	COG0069	glutamate synthase activity
K9D25_00545	COG3800	Transcriptional regulator
K9D25_00545	COG1396	sequence-specific DNA binding
K9D25_00550	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
K9D25_00555	COG4770	biotin carboxylase activity
K9D25_00600	COG1289	transmembrane transporter activity
K9D25_00610	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K9D25_00615	COG0668	transmembrane transport
K9D25_00620	COG0586	Pfam SNARE associated Golgi protein
K9D25_00640	COG4451	ribulose bisphosphate carboxylase, small
K9D25_00645	COG1850	ribulose-bisphosphate carboxylase activity
K9D25_00665	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
K9D25_00675	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K9D25_00685	COG1176	ABC-type spermidine putrescine transport system, permease component I
K9D25_00690	COG3842	ATPase activity
K9D25_00695	COG1653	transport
K9D25_00700	COG1917	Cupin 2, conserved barrel domain protein
K9D25_00700	COG1396	sequence-specific DNA binding
K9D25_00705	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K9D25_00730	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K9D25_00735	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K9D25_00740	COG0174	glutamine synthetase
K9D25_00750	COG2066	Belongs to the glutaminase family
K9D25_00785	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
K9D25_00795	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
K9D25_00800	COG1285	pathogenesis
K9D25_00810	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
K9D25_00815	COG0693	protein deglycase activity
K9D25_00825	COG1028	Short-chain dehydrogenase reductase Sdr
K9D25_00840	COG2943	transferase activity, transferring hexosyl groups
K9D25_00845	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
K9D25_00860	COG1121	(ABC) transporter
K9D25_00865	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K9D25_00870	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K9D25_00885	COG0861	Integral membrane protein TerC family
K9D25_00890	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
K9D25_00895	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
K9D25_00900	COG1984	allophanate hydrolase subunit 2
K9D25_00905	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
K9D25_00910	COG0625	glutathione transferase activity
K9D25_00930	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K9D25_00935	COG2368	4-hydroxyphenylacetate
K9D25_00950	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K9D25_00960	COG1176	ABC-type spermidine putrescine transport system, permease component I
K9D25_00965	COG1177	transmembrane transport
K9D25_00970	COG3842	ATPase activity
K9D25_00995	COG1012	belongs to the aldehyde dehydrogenase family
K9D25_01000	COG3938	Belongs to the proline racemase family
K9D25_01015	COG0765	amino acid transport
K9D25_01030	COG1850	ribulose-bisphosphate carboxylase activity
K9D25_01040	COG0287	Prephenate dehydrogenase
K9D25_01045	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
K9D25_01060	COG2186	Transcriptional regulator
K9D25_01085	COG0431	NADPH-dependent FMN reductase
K9D25_01100	COG0798	PFAM Bile acid sodium symporter
K9D25_01105	COG1393	Belongs to the ArsC family
K9D25_01130	COG2205	protein histidine kinase activity
K9D25_01135	COG4191	Histidine kinase
K9D25_01135	COG0784	Response regulator, receiver
K9D25_01160	COG1802	Transcriptional regulator
K9D25_01165	COG1879	ABC-type sugar transport system periplasmic component
K9D25_01170	COG1129	ABC transporter
K9D25_01175	COG1172	Belongs to the binding-protein-dependent transport system permease family
K9D25_01180	COG1028	Short-chain dehydrogenase reductase Sdr
K9D25_01185	COG1250	3-hydroxyacyl-CoA dehydrogenase
K9D25_01190	COG3246	L-lysine catabolic process to acetate
K9D25_01195	COG3386	PFAM SMP-30 Gluconolaconase
K9D25_01220	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9D25_01225	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K9D25_01230	COG1959	2 iron, 2 sulfur cluster binding
K9D25_01235	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K9D25_01245	COG4521	taurine ABC transporter
K9D25_01250	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
K9D25_01255	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9D25_01265	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
K9D25_01295	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
K9D25_01335	COG4191	Histidine kinase
K9D25_01340	COG0230	Belongs to the bacterial ribosomal protein bL34 family
K9D25_01345	COG0594	ribonuclease P activity
K9D25_01350	COG0706	membrane insertase activity
K9D25_01355	COG0218	Necessary for normal cell division and for the maintenance of normal septation
K9D25_01360	COG1063	alcohol dehydrogenase
K9D25_01370	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
K9D25_01375	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
K9D25_01380	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
K9D25_01385	COG1137	ATPase activity
K9D25_01390	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
K9D25_01405	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
K9D25_01420	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
K9D25_01435	COG0583	DNA-binding transcription factor activity
K9D25_01445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K9D25_01455	COG3842	ATPase activity
K9D25_01460	COG1176	ABC-type spermidine putrescine transport system, permease component I
K9D25_01465	COG1177	transmembrane transport
K9D25_01470	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
K9D25_01475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9D25_01480	COG0586	Pfam SNARE associated Golgi protein
K9D25_01490	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
K9D25_01495	COG1309	transcriptional regulator
K9D25_01510	COG0440	acetolactate synthase activity
K9D25_01515	COG0028	Belongs to the TPP enzyme family
K9D25_01520	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
K9D25_01525	COG0588	phosphoglycerate mutase activity
K9D25_01545	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
K9D25_01560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K9D25_01560	COG0072	phenylalanine-tRNA ligase activity
K9D25_01565	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
K9D25_01570	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
K9D25_01575	COG0291	Belongs to the bacterial ribosomal protein bL35 family
K9D25_01580	COG1968	undecaprenyl-diphosphatase activity
K9D25_01630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9D25_01635	COG0697	spore germination
K9D25_01645	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K9D25_01655	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
K9D25_01660	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K9D25_01680	COG4372	Transposase
K9D25_01685	COG3436	PFAM IS66 Orf2 family protein
K9D25_01720	COG4372	Transposase
K9D25_01725	COG3436	PFAM IS66 Orf2 family protein
K9D25_01770	COG0395	ABC-type sugar transport system, permease component
K9D25_01780	COG1653	transport
K9D25_01785	COG3842	ATPase activity
K9D25_01800	COG4670	ketone body catabolic process
K9D25_01810	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
K9D25_01860	COG0583	DNA-binding transcription factor activity
K9D25_01875	COG0243	molybdopterin cofactor binding
K9D25_01880	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
K9D25_01885	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K9D25_01890	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K9D25_01895	COG1116	anion transmembrane transporter activity
K9D25_01900	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9D25_01905	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K9D25_01910	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K9D25_01910	COG1116	anion transmembrane transporter activity
K9D25_01915	COG2201	protein-glutamate methylesterase activity
K9D25_01920	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K9D25_01930	COG4771	TonB-dependent receptor
K9D25_01940	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
K9D25_01945	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K9D25_01950	COG4558	Periplasmic binding protein
K9D25_01970	COG1802	Transcriptional regulator
K9D25_01990	COG1126	abc transporter atp-binding protein
K9D25_01995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K9D25_02000	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9D25_02005	COG3938	Belongs to the proline racemase family
K9D25_02010	COG4948	Mandelate Racemase Muconate Lactonizing
K9D25_02015	COG3938	Belongs to the proline racemase family
K9D25_02020	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
K9D25_02040	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
K9D25_02045	COG0642	Histidine kinase
K9D25_02060	COG1363	Peptidase, m42
K9D25_02065	COG2918	glutathione biosynthetic process
K9D25_02065	COG0189	ligase activity
K9D25_02075	COG1309	transcriptional regulator
K9D25_02080	COG1028	Short-chain dehydrogenase reductase Sdr
K9D25_02100	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K9D25_02115	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
K9D25_02125	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K9D25_02130	COG5328	Belongs to the UPF0262 family
K9D25_02140	COG0424	maF-like protein
K9D25_02145	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
K9D25_02260	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9D25_02305	COG1289	transmembrane transporter activity
K9D25_02310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
K9D25_02315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K9D25_02320	COG1845	cytochrome c oxidase, subunit III
K9D25_02335	COG0366	Alpha amylase catalytic
K9D25_02340	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K9D25_02350	COG1732	Glycine betaine
K9D25_02355	COG1174	glycine betaine transport
K9D25_02360	COG1125	glycine betaine transport
K9D25_02365	COG1174	glycine betaine transport
K9D25_02380	COG0395	ABC-type sugar transport system, permease component
K9D25_02385	COG1176	ABC-type spermidine putrescine transport system, permease component I
K9D25_02395	COG3842	ATPase activity
K9D25_02415	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
K9D25_02420	COG0010	Belongs to the arginase family
K9D25_02430	COG0156	8-amino-7-oxononanoate synthase activity
K9D25_02440	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K9D25_02445	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K9D25_02455	COG4566	intracellular signal transduction
K9D25_02460	COG4191	Histidine kinase
K9D25_02465	COG0436	Aminotransferase
K9D25_02485	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
K9D25_02490	COG1970	mechanosensitive ion channel activity
K9D25_02495	COG2205	protein histidine kinase activity
K9D25_02510	COG0432	Pfam Uncharacterised protein family UPF0047
K9D25_02530	COG0789	Transcriptional regulator
K9D25_02545	COG1201	RNA secondary structure unwinding
K9D25_02560	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
K9D25_02560	COG1793	dna ligase
K9D25_02575	COG0167	dihydroorotate dehydrogenase activity
K9D25_02600	COG0450	alkyl hydroperoxide reductase
K9D25_02610	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K9D25_02615	COG0242	peptide deformylase activity
K9D25_02630	COG5487	UPF0391 membrane protein
K9D25_02645	COG0784	Response regulator, receiver
K9D25_02650	COG2202	Pas domain
K9D25_02650	COG3920	Histidine kinase
K9D25_02665	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
K9D25_02670	COG2223	nitrite transmembrane transporter activity
K9D25_02680	COG2816	NAD+ diphosphatase activity
K9D25_02685	COG0717	Belongs to the dCTP deaminase family
K9D25_02695	COG2967	ApaG domain
K9D25_02700	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K9D25_02705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K9D25_02715	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
K9D25_02720	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
K9D25_02745	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K9D25_02905	COG1061	Type III restriction enzyme res subunit
K9D25_03190	COG0531	amino acid
K9D25_03195	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K9D25_03205	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9D25_03215	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
K9D25_03220	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
K9D25_03225	COG1309	transcriptional regulator
K9D25_03230	COG0318	PFAM AMP-dependent synthetase and ligase
K9D25_03230	COG0204	Acyl-transferase
K9D25_03245	COG2217	Heavy metal translocating P-type atpase
K9D25_03255	COG0348	domain, Protein
K9D25_03260	COG2010	Cytochrome c
K9D25_03275	COG3278	Belongs to the heme-copper respiratory oxidase family
K9D25_03285	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K9D25_03295	COG2862	Uncharacterized protein family, UPF0114
K9D25_03300	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
K9D25_03300	COG1648	precorrin-2 dehydrogenase activity
K9D25_03305	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
K9D25_03310	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
K9D25_03320	COG0124	histidyl-tRNA synthetase
K9D25_03335	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K9D25_03355	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K9D25_03355	COG2010	Cytochrome c
K9D25_03360	COG2863	cytochrome
K9D25_03365	COG0446	pyridine nucleotide-disulphide oxidoreductase
K9D25_03385	COG3258	Cytochrome c
K9D25_03405	COG1643	Atp-dependent helicase
K9D25_03415	COG1253	flavin adenine dinucleotide binding
K9D25_03420	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
K9D25_03435	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
K9D25_03445	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K9D25_03460	COG3813	Protein conserved in bacteria
K9D25_03470	COG1722	exodeoxyribonuclease VII activity
K9D25_03475	COG0123	including yeast histone deacetylase and acetoin utilization protein
K9D25_03480	COG0009	L-threonylcarbamoyladenylate synthase
K9D25_03490	COG0288	reversible hydration of carbon dioxide
K9D25_03495	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
K9D25_03500	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
K9D25_03505	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K9D25_03510	COG0356	it plays a direct role in the translocation of protons across the membrane
K9D25_03520	COG1196	nuclear chromosome segregation
K9D25_03530	COG2189	Belongs to the N(4) N(6)-methyltransferase family
K9D25_03535	COG3237	CsbD-like
K9D25_03550	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
K9D25_03570	COG0521	Mo-molybdopterin cofactor biosynthetic process
K9D25_03575	COG2321	neutral zinc metallopeptidase
K9D25_03580	COG0400	carboxylic ester hydrolase activity
K9D25_03585	COG0346	lactoylglutathione lyase activity
K9D25_03590	COG0583	DNA-binding transcription factor activity
K9D25_03595	COG1846	Transcriptional regulator
K9D25_03615	COG0587	DNA-directed DNA polymerase activity
K9D25_03660	COG3932	Exopolysaccharide synthesis, ExoD
K9D25_03665	COG0443	Heat shock 70 kDa protein
K9D25_03675	COG3706	GGDEF domain
K9D25_03705	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
K9D25_03715	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
K9D25_03715	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
K9D25_03720	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
K9D25_03725	COG0642	Histidine kinase
K9D25_03730	COG0745	RESPONSE REGULATOR receiver
K9D25_03740	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
K9D25_03750	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
K9D25_03755	COG2223	nitrite transmembrane transporter activity
K9D25_03770	COG2308	Evidence 4 Homologs of previously reported genes of
K9D25_03770	COG2307	Protein conserved in bacteria
K9D25_03825	COG0210	DNA helicase
K9D25_03855	COG0747	negative chemotaxis
K9D25_03860	COG0601	transmembrane transport
K9D25_03865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K9D25_03875	COG0247	lactate metabolic process
K9D25_03880	COG0277	FAD linked oxidase domain protein
K9D25_03885	COG0277	FAD linked oxidase domain protein
K9D25_03895	COG0129	dihydroxy-acid dehydratase activity
K9D25_03905	COG0277	FAD linked oxidase domain protein
K9D25_03910	COG2186	Transcriptional regulator
K9D25_03915	COG3842	ATPase activity
K9D25_03925	COG1175	transmembrane transport
K9D25_03930	COG0395	ABC-type sugar transport system, permease component
K9D25_03945	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K9D25_03955	COG1475	DNA binding
K9D25_03975	COG0840	transmembrane signaling receptor activity
K9D25_04010	COG1176	ABC-type spermidine putrescine transport system, permease component I
K9D25_04020	COG1250	3-hydroxyacyl-CoA dehydrogenase
K9D25_04025	COG2186	Transcriptional regulator
K9D25_04030	COG3395	kinase activity
K9D25_04035	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
K9D25_04040	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
K9D25_04045	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
K9D25_04045	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
K9D25_04050	COG0235	Class ii aldolase
K9D25_04070	COG0683	leucine binding
K9D25_04075	COG0559	Belongs to the binding-protein-dependent transport system permease family
K9D25_04090	COG0010	Belongs to the arginase family
K9D25_04095	COG4638	Rieske (2fe-2S)
K9D25_04100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K9D25_04105	COG3618	amidohydrolase
K9D25_04125	COG4774	siderophore transport
K9D25_04130	COG1120	ATPase activity
K9D25_04135	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K9D25_04150	COG1132	(ABC) transporter
K9D25_04160	COG5002	protein histidine kinase activity
K9D25_04160	COG2205	protein histidine kinase activity
K9D25_04160	COG0784	Response regulator, receiver
K9D25_04165	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K9D25_04170	COG3920	Histidine kinase
K9D25_04190	COG0683	leucine binding
K9D25_04220	COG3119	arylsulfatase activity
K9D25_04230	COG0583	DNA-binding transcription factor activity
K9D25_04250	COG0559	Belongs to the binding-protein-dependent transport system permease family
K9D25_04265	COG0410	ABC transporter
K9D25_04280	COG2183	response to ionizing radiation
K9D25_04285	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
K9D25_04315	COG2186	Transcriptional regulator
K9D25_04320	COG1566	PFAM secretion protein HlyD family protein
K9D25_04330	COG1289	transmembrane transporter activity
K9D25_04335	COG2376	Dihydroxyacetone kinase
K9D25_04350	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
K9D25_04360	COG1461	Dihydroxyacetone kinase
K9D25_04370	COG3842	ATPase activity
K9D25_04385	COG0395	ABC-type sugar transport system, permease component
K9D25_04390	COG1175	transmembrane transport
K9D25_04405	COG3842	ATPase activity
K9D25_04410	COG3842	ATPase activity
K9D25_04420	COG0395	ABC-type sugar transport system, permease component
K9D25_04455	COG0179	Fumarylacetoacetate (FAA) hydrolase
K9D25_04495	COG3842	ATPase activity
K9D25_04510	COG1349	DNA-binding transcription factor activity
K9D25_04530	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K9D25_04535	COG0434	BtpA family
K9D25_04540	COG1349	DNA-binding transcription factor activity
K9D25_04550	COG3842	ATPase activity
K9D25_04555	COG0395	ABC-type sugar transport system, permease component
K9D25_04565	COG1175	transmembrane transport
K9D25_04570	COG0402	S-adenosylhomocysteine deaminase activity
K9D25_04575	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K9D25_04585	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9D25_04595	COG1802	Transcriptional regulator
K9D25_04635	COG0745	RESPONSE REGULATOR receiver
K9D25_04640	COG0704	Plays a role in the regulation of phosphate uptake
K9D25_04645	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
K9D25_04655	COG0573	inorganic phosphate transmembrane transporter activity
K9D25_04660	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K9D25_04665	COG5002	protein histidine kinase activity
K9D25_04670	COG2326	polyphosphate kinase activity
K9D25_04685	COG3158	transport of potassium into the cell
K9D25_04690	COG1309	transcriptional regulator
K9D25_04700	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
K9D25_04720	COG0443	Heat shock 70 kDa protein
K9D25_04725	COG0484	heat shock protein binding
K9D25_04730	COG3963	phosphatidate phosphatase activity
K9D25_04740	COG0284	orotidine-5'-phosphate decarboxylase activity
K9D25_04755	COG0828	Belongs to the bacterial ribosomal protein bS21 family
K9D25_04785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K9D25_04790	COG2171	N-acyltransferase activity
K9D25_04800	COG0574	Belongs to the PEP-utilizing enzyme family
K9D25_04800	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
K9D25_04805	COG2259	Doxx family
K9D25_04815	COG0751	glycine-tRNA ligase activity
K9D25_04825	COG0752	glycyl-tRNA synthetase alpha subunit
K9D25_04830	COG1570	exodeoxyribonuclease VII activity
K9D25_04840	COG1663	tetraacyldisaccharide 4'-kinase activity
K9D25_04845	COG1519	Transferase
K9D25_04860	COG0483	inositol monophosphate 1-phosphatase activity
K9D25_04900	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
K9D25_04915	COG1473	amidohydrolase
K9D25_04930	COG0670	Belongs to the BI1 family
K9D25_04940	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K9D25_04950	COG0180	Tryptophanyl-tRNA synthetase
K9D25_04960	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
K9D25_04980	COG0204	Acyl-transferase
K9D25_04985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K9D25_04990	COG1702	phosphate starvation-inducible protein PhoH
K9D25_04995	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
K9D25_05000	COG1253	flavin adenine dinucleotide binding
K9D25_05005	COG0815	Transfers the fatty acyl group on membrane lipoproteins
K9D25_05010	COG1396	sequence-specific DNA binding
K9D25_05015	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
K9D25_05020	COG0220	tRNA (guanine-N7-)-methyltransferase activity
K9D25_05065	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
K9D25_05070	COG0519	Catalyzes the synthesis of GMP from XMP
K9D25_05075	COG0354	folic acid binding
K9D25_05080	COG1764	response to oxidative stress
K9D25_05090	COG0019	diaminopimelate decarboxylase activity
K9D25_05105	COG3454	Phosphonate metabolism
K9D25_05110	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
K9D25_05120	COG0616	signal peptide processing
K9D25_05125	COG0776	regulation of translation
K9D25_05135	COG2423	ornithine cyclodeaminase activity
K9D25_05140	COG4208	sulfate ABC transporter
K9D25_05150	COG4150	thiosulfate binding
K9D25_05160	COG0135	phosphoribosylanthranilate isomerase activity
K9D25_05165	COG0133	tryptophan synthase activity
K9D25_05170	COG0159	tryptophan synthase activity
K9D25_05175	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
K9D25_05185	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
K9D25_05195	COG0742	ribosomal rna small subunit methyltransferase
K9D25_05200	COG1187	pseudouridine synthase activity
K9D25_05205	COG0590	tRNA wobble adenosine to inosine editing
K9D25_05210	COG1752	Esterase of the alpha-beta hydrolase superfamily
K9D25_05215	COG0151	Belongs to the GarS family
K9D25_05220	COG0577	efflux transmembrane transporter activity
K9D25_05220	COG1136	(ABC) transporter
K9D25_05225	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9D25_05250	COG3754	Rhamnan synthesis protein F
K9D25_05255	COG0142	geranyltranstransferase activity
K9D25_05260	COG1742	UPF0060 membrane protein
K9D25_05265	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
K9D25_05270	COG0779	Required for maturation of 30S ribosomal subunits
K9D25_05285	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
K9D25_05290	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
K9D25_05295	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
K9D25_05300	COG1733	regulation of RNA biosynthetic process
K9D25_05310	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
K9D25_05315	COG1185	polyribonucleotide nucleotidyltransferase activity
K9D25_05335	COG0247	lactate metabolic process
K9D25_05340	COG0277	FAD linked oxidase domain protein
K9D25_05350	COG0277	FAD linked oxidase domain protein
K9D25_05375	COG0612	Peptidase, M16
K9D25_05380	COG0612	Peptidase, M16
K9D25_05390	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
K9D25_05395	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
K9D25_05405	COG0583	DNA-binding transcription factor activity
K9D25_05410	COG0196	riboflavin kinase activity
K9D25_05425	COG3920	Histidine kinase
K9D25_05430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
K9D25_05440	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
K9D25_05455	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
K9D25_05470	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K9D25_05470	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
K9D25_05485	COG0101	tRNA pseudouridine synthase activity
K9D25_05510	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
K9D25_05520	COG2862	Uncharacterized protein family, UPF0114
K9D25_05525	COG0640	Transcriptional regulator
K9D25_05545	COG0539	negative regulation of cytoplasmic translation
K9D25_05570	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
K9D25_05575	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
K9D25_05595	COG1136	(ABC) transporter
K9D25_05605	COG1785	Belongs to the alkaline phosphatase family
K9D25_05620	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K9D25_05625	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
K9D25_05640	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
K9D25_05645	COG3383	formate dehydrogenase (NAD+) activity
K9D25_05660	COG0606	chelatase, subunit chli
K9D25_05670	COG0071	Belongs to the small heat shock protein (HSP20) family
K9D25_05680	COG0189	ligase activity
K9D25_05685	COG0792	nuclease activity
K9D25_05690	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
K9D25_05705	COG0635	Involved in the biosynthesis of porphyrin-containing compound
K9D25_05710	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
K9D25_05715	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
K9D25_05725	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
K9D25_05740	COG1072	(Pantothenic acid kinase))
K9D25_05745	COG0140	phosphoribosyl-ATP diphosphatase activity
K9D25_05750	COG0107	imidazoleglycerol-phosphate synthase activity
K9D25_05755	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
K9D25_05760	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
K9D25_05770	COG0131	Imidazoleglycerol-phosphate dehydratase
K9D25_05775	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
K9D25_05785	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
K9D25_05790	COG1396	sequence-specific DNA binding
K9D25_05800	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
K9D25_05810	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
K9D25_05815	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
K9D25_05820	COG0237	dephospho-CoA kinase activity
K9D25_05825	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
K9D25_05830	COG0424	maF-like protein
K9D25_05835	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
K9D25_05840	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
K9D25_05845	COG1981	membrane
K9D25_05850	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
K9D25_05860	COG1331	Highly conserved protein containing a thioredoxin domain
K9D25_05865	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
K9D25_05875	COG0357	Ribosomal RNA small subunit methyltransferase G
K9D25_05900	COG0495	leucyl-tRNA aminoacylation
K9D25_05915	COG2855	membrane
K9D25_05925	COG0501	Belongs to the peptidase M48B family
K9D25_05980	COG0175	sulfate reduction
K9D25_05995	COG0582	viral genome integration into host DNA
K9D25_06010	COG4783	chaperone-mediated protein folding
K9D25_06015	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K9D25_06025	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
K9D25_06045	COG0227	Belongs to the bacterial ribosomal protein bL28 family
K9D25_06060	COG1309	transcriptional regulator
K9D25_06080	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9D25_06095	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
K9D25_06105	COG2144	transferase activity, transferring acyl groups
K9D25_06110	COG0438	transferase activity, transferring glycosyl groups
K9D25_06120	COG2072	flavoprotein involved in K transport
K9D25_06160	COG4691	Plasmid stability protein
K9D25_06180	COG5489	Protein of unknown function (DUF736)
K9D25_06235	COG0741	lytic transglycosylase activity
K9D25_06255	COG0745	RESPONSE REGULATOR receiver
K9D25_06260	COG2205	protein histidine kinase activity
K9D25_06285	COG2132	Multicopper oxidase
K9D25_06290	COG4974	Belongs to the 'phage' integrase family
K9D25_06295	COG0517	IMP dehydrogenase activity
K9D25_06315	COG1937	Protein conserved in bacteria
K9D25_06325	COG2814	Major facilitator Superfamily
K9D25_06330	COG1238	metal cluster binding
K9D25_06360	COG3177	Filamentation induced by cAMP protein fic
K9D25_06370	COG4962	Type ii secretion system protein e
K9D25_06385	COG3451	type IV secretory pathway VirB4
K9D25_06400	COG3846	protein secretion by the type IV secretion system
K9D25_06405	COG3701	Conjugal transfer protein
K9D25_06425	COG0583	DNA-binding transcription factor activity
K9D25_06430	COG1002	Type II restriction enzyme, methylase subunits
K9D25_06435	COG1061	Type III restriction enzyme res subunit
K9D25_06440	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
K9D25_06450	COG4974	Belongs to the 'phage' integrase family
K9D25_06485	COG3023	N-Acetylmuramoyl-L-alanine amidase
K9D25_06510	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
K9D25_06515	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
K9D25_06530	COG1846	Transcriptional regulator
K9D25_06540	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9D25_06545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9D25_06550	COG1538	Outer membrane efflux protein
K9D25_06580	COG1132	(ABC) transporter
K9D25_06585	COG0318	PFAM AMP-dependent synthetase and ligase
K9D25_06605	COG3220	belongs to the UPF0276 family
K9D25_06615	COG1595	DNA-templated transcription, initiation
K9D25_06645	COG3795	YCII-related domain
K9D25_06650	COG4941	Belongs to the sigma-70 factor family
K9D25_06655	COG0708	Exodeoxyribonuclease III
K9D25_06660	COG1335	isochorismatase
K9D25_06665	COG0753	catalase activity
K9D25_06670	COG2094	Belongs to the DNA glycosylase MPG family
K9D25_06675	COG1879	ABC-type sugar transport system periplasmic component
K9D25_06680	COG1172	Belongs to the binding-protein-dependent transport system permease family
K9D25_06685	COG1129	ABC transporter
K9D25_06690	COG0673	inositol 2-dehydrogenase activity
K9D25_06700	COG1609	Transcriptional regulator
K9D25_06715	COG1940	carbohydrate kinase activity
K9D25_06725	COG0583	DNA-binding transcription factor activity
K9D25_06740	COG0477	Major facilitator Superfamily
K9D25_06775	COG1802	Transcriptional regulator
K9D25_06785	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K9D25_06785	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K9D25_06800	COG0438	transferase activity, transferring glycosyl groups
K9D25_06860	COG3842	ATPase activity
K9D25_06870	COG1176	ABC-type spermidine putrescine transport system, permease component I
K9D25_06880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9D25_06885	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9D25_06890	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
K9D25_06905	COG1252	NADH dehydrogenase
K9D25_06920	COG3685	Protein conserved in bacteria
K9D25_06945	COG1595	DNA-templated transcription, initiation
K9D25_06960	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K9D25_06965	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
K9D25_06970	COG4191	Histidine kinase
K9D25_07000	COG2010	Cytochrome c
K9D25_07015	COG2217	Heavy metal translocating P-type atpase
K9D25_07040	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K9D25_07050	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K9D25_07055	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K9D25_07060	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K9D25_07065	COG0261	This protein binds to 23S rRNA in the presence of protein L20
K9D25_07070	COG0211	Belongs to the bacterial ribosomal protein bL27 family
K9D25_07080	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
K9D25_07085	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
K9D25_07105	COG3842	ATPase activity
K9D25_07115	COG0573	inorganic phosphate transmembrane transporter activity
K9D25_07120	COG2140	Oxalate decarboxylase
K9D25_07135	COG1921	L-seryl-tRNASec selenium transferase activity
K9D25_07145	COG2864	formate dehydrogenase
K9D25_07150	COG0437	4 iron, 4 sulfur cluster binding
K9D25_07160	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9D25_07165	COG1305	Transglutaminase-like
K9D25_07170	COG0709	Synthesizes selenophosphate from selenide and ATP
K9D25_07175	COG3875	lactate racemase activity
K9D25_07180	COG1641	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes
K9D25_07190	COG1691	(AIR) carboxylase
K9D25_07195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K9D25_07220	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
K9D25_07225	COG4133	protoheme IX ABC transporter activity
K9D25_07230	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K9D25_07235	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
K9D25_07240	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
K9D25_07245	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
K9D25_07250	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
K9D25_07255	COG0355	proton-transporting ATP synthase activity, rotational mechanism
K9D25_07260	COG0351	phosphomethylpyrimidine kinase
K9D25_07260	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
K9D25_07260	COG0352	thiamine-phosphate diphosphorylase activity
K9D25_07265	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
K9D25_07270	COG0513	Belongs to the DEAD box helicase family
K9D25_07285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K9D25_07285	COG2813	Specifically methylates the guanine in position
K9D25_07290	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K9D25_07300	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
K9D25_07305	COG0287	Prephenate dehydrogenase
K9D25_07330	COG0789	Transcriptional regulator
K9D25_07340	COG0165	Argininosuccinate lyase
K9D25_07345	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9D25_07350	COG0697	spore germination
K9D25_07355	COG1250	3-hydroxyacyl-CoA dehydrogenase
K9D25_07360	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
K9D25_07365	COG2086	electron transfer activity
K9D25_07390	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
K9D25_07405	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
K9D25_07410	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
K9D25_07415	COG0477	Major facilitator Superfamily
K9D25_07425	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
K9D25_07435	COG0799	negative regulation of ribosome biogenesis
K9D25_07440	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
K9D25_07450	COG0793	Belongs to the peptidase S41A family
K9D25_07460	COG0494	nUDIX hydrolase
K9D25_07465	COG1309	transcriptional regulator
K9D25_07485	COG3118	belongs to the thioredoxin family
K9D25_07490	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
K9D25_07505	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
K9D25_07510	COG1802	Transcriptional regulator
K9D25_07515	COG2835	tetraacyldisaccharide 4'-kinase activity
K9D25_07515	COG1663	tetraacyldisaccharide 4'-kinase activity
K9D25_07520	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K9D25_07525	COG1946	Acyl-CoA thioesterase
K9D25_07530	COG0347	Belongs to the P(II) protein family
K9D25_07535	COG0004	ammonium transporteR
K9D25_07540	COG0436	Aminotransferase
K9D25_07545	COG1674	ftsk spoiiie
K9D25_07565	COG0019	diaminopimelate decarboxylase activity
K9D25_07580	COG2884	Cell division ATP-binding protein ftsE
K9D25_07600	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
K9D25_07610	COG0129	dihydroxy-acid dehydratase activity
K9D25_07615	COG0363	glucosamine-6-phosphate deaminase activity
K9D25_07620	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
K9D25_07640	COG1802	Transcriptional regulator
K9D25_07650	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
K9D25_07655	COG4957	zinc ion binding
K9D25_07665	COG1028	Short-chain dehydrogenase reductase Sdr
K9D25_07680	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K9D25_07680	COG2080	2 iron, 2 sulfur cluster binding
K9D25_07685	COG0402	S-adenosylhomocysteine deaminase activity
K9D25_07695	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K9D25_07705	COG1126	abc transporter atp-binding protein
K9D25_07740	COG5507	3-demethylubiquinone-9 3-methyltransferase
K9D25_07745	COG0670	Belongs to the BI1 family
K9D25_07755	COG1136	(ABC) transporter
K9D25_07775	COG0667	Aldo Keto reductase
K9D25_07780	COG2917	probably involved in intracellular septation
K9D25_07785	COG0552	protein localization to endoplasmic reticulum
K9D25_07790	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K9D25_07795	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
K9D25_07805	COG0820	rRNA (adenine-C2-)-methyltransferase activity
K9D25_07815	COG0137	argininosuccinate synthase activity
K9D25_07825	COG4977	sequence-specific DNA binding
K9D25_07835	COG0517	IMP dehydrogenase activity
K9D25_07835	COG1994	Peptidase M50
K9D25_07850	COG1217	gtp-binding protein TYPA
K9D25_07855	COG1247	-acetyltransferase
K9D25_07860	COG1872	DUF167
K9D25_07890	COG1704	LemA family
K9D25_07895	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
K9D25_07905	COG1295	ribonuclease BN
K9D25_07910	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
K9D25_07915	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
K9D25_07925	COG0400	carboxylic ester hydrolase activity
K9D25_07930	COG0739	heme binding
K9D25_07945	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
K9D25_07950	COG1053	succinate dehydrogenase
K9D25_07960	COG1280	lysine exporter protein (LysE YggA)
K9D25_07965	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K9D25_08000	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
K9D25_08015	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
K9D25_08025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K9D25_08030	COG0508	dehydrogenase complex catalyzes the overall conversion of
K9D25_08035	COG0567	Dehydrogenase, E1 component
K9D25_08040	COG0039	L-malate dehydrogenase activity
K9D25_08050	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
K9D25_08065	COG1196	nuclear chromosome segregation
K9D25_08065	COG3264	Mechanosensitive ion channel
K9D25_08075	COG0523	cobalamin synthesis protein
K9D25_08090	COG0140	phosphoribosyl-ATP diphosphatase activity
K9D25_08095	COG1238	metal cluster binding
K9D25_08100	COG4208	sulfate ABC transporter
K9D25_08105	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
K9D25_08110	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
K9D25_08115	COG0175	sulfate reduction
K9D25_08125	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
K9D25_08185	COG0583	DNA-binding transcription factor activity
K9D25_08215	COG3181	Tripartite tricarboxylate transporter family receptor
K9D25_08225	COG0673	inositol 2-dehydrogenase activity
K9D25_08245	COG0583	DNA-binding transcription factor activity
K9D25_08255	COG0673	inositol 2-dehydrogenase activity
K9D25_08265	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K9D25_08270	COG0583	DNA-binding transcription factor activity
K9D25_08275	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
K9D25_08305	COG0523	cobalamin synthesis protein
K9D25_08315	COG1802	Transcriptional regulator
K9D25_08325	COG1960	acyl-CoA dehydrogenase activity
K9D25_08335	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K9D25_08350	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9D25_08355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9D25_08370	COG1028	Short-chain dehydrogenase reductase Sdr
K9D25_08375	COG0673	inositol 2-dehydrogenase activity
K9D25_08380	COG3246	L-lysine catabolic process to acetate
K9D25_08390	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
K9D25_08395	COG2084	Dehydrogenase
K9D25_08405	COG1028	Short-chain dehydrogenase reductase Sdr
K9D25_08415	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9D25_08420	COG1116	anion transmembrane transporter activity
K9D25_08440	COG1172	Belongs to the binding-protein-dependent transport system permease family
K9D25_08460	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
K9D25_08465	COG2201	protein-glutamate methylesterase activity
K9D25_08470	COG0745	RESPONSE REGULATOR receiver
K9D25_08475	COG0835	chemotaxis
K9D25_08480	COG0784	Response regulator, receiver
K9D25_08480	COG2198	Histidine kinase
K9D25_08480	COG0643	Histidine kinase
K9D25_08515	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K9D25_08520	COG1987	bacterial-type flagellum assembly
K9D25_08525	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
K9D25_08530	COG5443	negative regulation of bacterial-type flagellum assembly
K9D25_08550	COG1749	Flagellar hook protein flgE
K9D25_08555	COG1157	protein secretion by the type III secretion system
K9D25_08560	COG4786	Flagellar basal body rod
K9D25_08570	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
K9D25_08585	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K9D25_08590	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
K9D25_08595	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
K9D25_08605	COG1815	bacterial-type flagellum-dependent cell motility
K9D25_08610	COG1558	bacterial-type flagellum-dependent cell motility
K9D25_08620	COG4786	Flagellar basal body rod
K9D25_08630	COG1706	bacterial-type flagellum-dependent cell motility
K9D25_08640	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
K9D25_08650	COG1338	Plays a role in the flagellum-specific transport system
K9D25_08670	COG1360	Flagellar Motor Protein
K9D25_08690	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
K9D25_08695	COG0745	RESPONSE REGULATOR receiver
K9D25_08705	COG2204	response regulator
K9D25_08730	COG0840	transmembrane signaling receptor activity
K9D25_08745	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
K9D25_08775	COG3454	Phosphonate metabolism
K9D25_08780	COG2188	Transcriptional regulator
K9D25_08785	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
K9D25_08795	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
K9D25_08815	COG1349	DNA-binding transcription factor activity
K9D25_08840	COG0489	protein tyrosine kinase activity
K9D25_08840	COG3206	protein involved in exopolysaccharide biosynthesis
K9D25_08845	COG1596	polysaccharide export
K9D25_08850	COG4464	protein tyrosine phosphatase activity
K9D25_08875	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
K9D25_08880	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
K9D25_08885	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
K9D25_08900	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
K9D25_08930	COG0438	transferase activity, transferring glycosyl groups
K9D25_08945	COG0367	asparagine synthase
K9D25_08950	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K9D25_08975	COG4372	Transposase
K9D25_08980	COG3436	PFAM IS66 Orf2 family protein
K9D25_09000	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
K9D25_09005	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
K9D25_09010	COG1522	sequence-specific DNA binding
K9D25_09070	COG0642	Histidine kinase
K9D25_09080	COG3038	cytochrome b561
K9D25_09090	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
K9D25_09100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9D25_09105	COG1129	ABC transporter
K9D25_09105	COG0842	Transport permease protein
K9D25_09110	COG0842	Transport permease protein
K9D25_09115	COG1309	transcriptional regulator
K9D25_09135	COG0469	pyruvate kinase activity
K9D25_09160	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
K9D25_09175	COG3023	N-Acetylmuramoyl-L-alanine amidase
K9D25_09180	COG2001	Belongs to the MraZ family
K9D25_09185	COG0275	rRNA processing
K9D25_09200	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
K9D25_09205	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
K9D25_09210	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
K9D25_09220	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
K9D25_09230	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
K9D25_09235	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
K9D25_09240	COG0812	UDP-N-acetylmuramate dehydrogenase activity
K9D25_09245	COG1181	Belongs to the D-alanine--D-alanine ligase family
K9D25_09250	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
K9D25_09255	COG0849	cell division
K9D25_09260	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
K9D25_09270	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K9D25_09290	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
K9D25_09295	COG1335	isochorismatase
K9D25_09305	COG0006	proline dipeptidase activity
K9D25_09310	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
K9D25_09315	COG0583	DNA-binding transcription factor activity
K9D25_09320	COG0210	DNA helicase
K9D25_09325	COG2264	protein methyltransferase activity
K9D25_09335	COG0277	FAD linked oxidase domain protein
K9D25_09345	COG0560	Phosphoserine phosphatase
K9D25_09350	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
K9D25_09360	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
K9D25_09380	COG3750	Belongs to the UPF0335 family
K9D25_09405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
K9D25_09415	COG0330	HflC and HflK could
K9D25_09420	COG0330	HflC and HflK could
K9D25_09435	COG0114	fumarate hydratase activity
K9D25_09485	COG0257	Belongs to the bacterial ribosomal protein bL36 family
K9D25_09495	COG0328	RNA-DNA hybrid ribonuclease activity
K9D25_09500	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
K9D25_09505	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
K9D25_09535	COG0678	peroxiredoxin activity
K9D25_09545	COG1678	Uncharacterized ACR, COG1678
K9D25_09570	COG3588	fructose-bisphosphate aldolase
K9D25_09595	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
K9D25_09600	COG0483	inositol monophosphate 1-phosphatase activity
K9D25_09630	COG1132	(ABC) transporter
K9D25_09635	COG0254	rRNA binding
K9D25_09650	COG0604	alcohol dehydrogenase
K9D25_09660	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
K9D25_09665	COG1692	metallophosphoesterase
K9D25_09675	COG0217	transcriptional regulatory protein
K9D25_09690	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
K9D25_09695	COG0632	four-way junction helicase activity
K9D25_09705	COG2255	four-way junction helicase activity
K9D25_09725	COG0824	Thioesterase
K9D25_09730	COG0811	peptide transport
K9D25_09735	COG0848	biopolymer transport protein
K9D25_09745	COG0823	Involved in the tonB-independent uptake of proteins
K9D25_09750	COG2885	chlorophyll binding
K9D25_09760	COG0037	tRNA processing
K9D25_09765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
K9D25_09770	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
K9D25_09775	COG4175	Glycine betaine
K9D25_09780	COG4176	ABC-type proline glycine betaine transport system permease component
K9D25_09790	COG1012	belongs to the aldehyde dehydrogenase family
K9D25_09795	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
K9D25_09800	COG0671	phosphoesterase, PA-phosphatase related
K9D25_09815	COG2181	nitrate reductase activity
K9D25_09815	COG0247	lactate metabolic process
K9D25_09820	COG1902	pentaerythritol trinitrate reductase activity
K9D25_09820	COG0446	pyridine nucleotide-disulphide oxidoreductase
K9D25_09870	COG1760	l-serine dehydratase
K9D25_09880	COG0404	The glycine cleavage system catalyzes the degradation of glycine
K9D25_09880	COG0446	pyridine nucleotide-disulphide oxidoreductase
K9D25_09890	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9D25_09940	COG3750	Belongs to the UPF0335 family
K9D25_10055	COG4695	Portal protein
K9D25_10060	COG0740	serine-type endopeptidase activity
K9D25_10210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K9D25_10215	COG0800	Aldolase
K9D25_10225	COG3895	Periplasmic Protein
K9D25_10245	COG2514	catechol 2,3-dioxygenase activity
K9D25_10250	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
K9D25_10260	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
K9D25_10265	COG0045	succinate-CoA ligase (ADP-forming) activity
K9D25_10275	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
K9D25_10280	COG2084	Dehydrogenase
K9D25_10285	COG3622	Belongs to the hyi family
K9D25_10290	COG3960	tartronate-semialdehyde synthase activity
K9D25_10295	COG1414	Transcriptional regulator
K9D25_10305	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K9D25_10320	COG1802	Transcriptional regulator
K9D25_10335	COG0494	nUDIX hydrolase
K9D25_10340	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
K9D25_10350	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
K9D25_10355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
K9D25_10380	COG0024	Methionine aminopeptidase
K9D25_10385	COG2003	Belongs to the UPF0758 family
K9D25_10390	COG1231	oxidoreductase activity
K9D25_10400	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
K9D25_10410	COG2249	NAD(P)H dehydrogenase (quinone) activity
K9D25_10420	COG0402	S-adenosylhomocysteine deaminase activity
K9D25_10425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9D25_10435	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K9D25_10450	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
K9D25_10455	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
K9D25_10475	COG1108	ABC-type Mn2 Zn2 transport systems permease components
K9D25_10480	COG0803	Belongs to the bacterial solute-binding protein 9 family
K9D25_10485	COG0523	cobalamin synthesis protein
K9D25_10500	COG4689	acetoacetate decarboxylase
K9D25_10505	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
K9D25_10515	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
K9D25_10550	COG1028	Short-chain dehydrogenase reductase Sdr
K9D25_10555	COG0564	pseudouridine synthase activity
K9D25_10565	COG0837	glucose binding
K9D25_10580	COG0138	bifunctional purine biosynthesis protein purh
K9D25_10585	COG3047	cAMP biosynthetic process
K9D25_10595	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K9D25_10600	COG2264	protein methyltransferase activity
K9D25_10610	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
K9D25_10615	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
K9D25_10620	COG0181	hydroxymethylbilane synthase activity
K9D25_10665	COG4536	flavin adenine dinucleotide binding
K9D25_10670	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
K9D25_10675	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
K9D25_10685	COG4974	Belongs to the 'phage' integrase family
K9D25_10690	COG0825	malonyl-CoA metabolic process
K9D25_10695	COG3034	peptidoglycan biosynthetic process
K9D25_10705	COG0653	protein targeting
K9D25_10710	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
K9D25_10750	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
K9D25_10755	COG0494	nUDIX hydrolase
K9D25_10760	COG2226	methyltransferase
K9D25_10765	COG1040	competence protein
K9D25_10770	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
K9D25_10775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K9D25_10785	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
K9D25_10795	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
K9D25_10805	COG0469	pyruvate kinase activity
K9D25_10810	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
K9D25_10815	COG0228	four-way junction DNA binding
K9D25_10820	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
K9D25_10825	COG0336	Belongs to the RNA methyltransferase TrmD family
K9D25_10830	COG0335	large ribosomal subunit rRNA binding
K9D25_10835	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
K9D25_10850	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
K9D25_10860	COG3038	cytochrome b561
K9D25_10865	COG0066	3-isopropylmalate dehydratase activity
K9D25_10895	COG0473	3-isopropylmalate dehydrogenase activity
K9D25_10905	COG0142	geranyltranstransferase activity
K9D25_10910	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
K9D25_10915	COG0333	Belongs to the bacterial ribosomal protein bL32 family
K9D25_10925	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
K9D25_10935	COG1028	Short-chain dehydrogenase reductase Sdr
K9D25_10955	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K9D25_10965	COG3339	Conserved Protein
K9D25_10985	COG2890	protein-(glutamine-N5) methyltransferase activity
K9D25_10990	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
K9D25_11000	COG0527	aspartate kinase activity
K9D25_11005	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
K9D25_11015	COG0542	response to heat
K9D25_11025	COG1210	Utp--glucose-1-phosphate uridylyltransferase
K9D25_11030	COG2951	lytic endotransglycosylase activity
K9D25_11045	COG0067	glutamate synthase
K9D25_11045	COG0069	glutamate synthase activity
K9D25_11045	COG0070	glutamate synthase
K9D25_11055	COG0071	Belongs to the small heat shock protein (HSP20) family
K9D25_11070	COG0483	inositol monophosphate 1-phosphatase activity
K9D25_11115	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
K9D25_11125	COG0583	DNA-binding transcription factor activity
K9D25_11130	COG0735	belongs to the Fur family
K9D25_11135	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K9D25_11145	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K9D25_11150	COG0077	Prephenate dehydratase
K9D25_11150	COG1605	Chorismate mutase
K9D25_11155	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
K9D25_11160	COG3474	cytochrome
K9D25_11165	COG4166	transmembrane transport
K9D25_11170	COG4166	transmembrane transport
K9D25_11175	COG4174	ABC transporter (Permease)
K9D25_11180	COG4239	(ABC) transporter, permease
K9D25_11195	COG4172	Belongs to the ABC transporter superfamily
K9D25_11215	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
K9D25_11230	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
K9D25_11235	COG0484	heat shock protein binding
K9D25_11245	COG0259	pyridoxamine-phosphate oxidase activity
K9D25_11250	COG1028	Short-chain dehydrogenase reductase Sdr
K9D25_11265	COG1376	ErfK ybiS ycfS ynhG family protein
K9D25_11265	COG1388	LysM domain
K9D25_11270	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K9D25_11280	COG0546	phosphoglycolate phosphatase activity
K9D25_11290	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K9D25_11295	COG0288	reversible hydration of carbon dioxide
K9D25_11345	COG1566	PFAM secretion protein HlyD family protein
K9D25_11370	COG4191	Histidine kinase
K9D25_11375	COG4566	intracellular signal transduction
K9D25_11380	COG4566	intracellular signal transduction
K9D25_11385	COG0783	Belongs to the Dps family
K9D25_11415	COG0683	leucine binding
K9D25_11435	COG2226	methyltransferase
K9D25_11440	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K9D25_11450	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
K9D25_11455	COG0756	dUTP diphosphatase activity
K9D25_11460	COG1959	2 iron, 2 sulfur cluster binding
K9D25_11470	COG2205	protein histidine kinase activity
K9D25_11475	COG3178	'Phosphotransferase
K9D25_11480	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
K9D25_11485	COG2887	Belongs to the helicase family. UvrD subfamily
K9D25_11490	COG1074	ATP-dependent DNA helicase activity
K9D25_11505	COG3161	chorismate lyase activity
K9D25_11510	COG3174	membrane
K9D25_11515	COG0028	Belongs to the TPP enzyme family
K9D25_11520	COG1294	oxidase, subunit
K9D25_11525	COG1271	oxidase subunit
K9D25_11535	COG1028	Short-chain dehydrogenase reductase Sdr
K9D25_11545	COG4191	Histidine kinase
K9D25_11555	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K9D25_11580	COG0564	pseudouridine synthase activity
K9D25_11585	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K9D25_11615	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
K9D25_11645	COG1309	transcriptional regulator
K9D25_11650	COG1834	amidinotransferase
K9D25_11660	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K9D25_11665	COG4215	(ABC) transporter
K9D25_11675	COG1473	amidohydrolase
K9D25_11680	COG0583	DNA-binding transcription factor activity
K9D25_11685	COG3842	ATPase activity
K9D25_11695	COG1176	ABC-type spermidine putrescine transport system, permease component I
K9D25_11720	COG4638	Rieske (2fe-2S)
K9D25_11730	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K9D25_11735	COG1012	belongs to the aldehyde dehydrogenase family
K9D25_11740	COG1126	abc transporter atp-binding protein
K9D25_11745	COG0765	amino acid transport
K9D25_11750	COG0765	amino acid transport
K9D25_11755	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K9D25_11760	COG3608	succinylglutamate desuccinylase aspartoacylase
K9D25_11765	COG0006	proline dipeptidase activity
K9D25_11770	COG2423	ornithine cyclodeaminase activity
K9D25_11775	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K9D25_11780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
K9D25_11785	COG1522	sequence-specific DNA binding
K9D25_11795	COG0402	S-adenosylhomocysteine deaminase activity
K9D25_11800	COG3842	ATPase activity
K9D25_11810	COG1176	ABC-type spermidine putrescine transport system, permease component I
K9D25_11820	COG0590	tRNA wobble adenosine to inosine editing
K9D25_11825	COG0583	DNA-binding transcription factor activity
K9D25_11835	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K9D25_11840	COG2010	Cytochrome c
K9D25_11840	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
K9D25_11860	COG0243	molybdopterin cofactor binding
K9D25_11890	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K9D25_11910	COG1126	abc transporter atp-binding protein
K9D25_11920	COG0583	DNA-binding transcription factor activity
K9D25_11940	COG1132	(ABC) transporter
K9D25_11950	COG0786	glutamate:sodium symporter activity
K9D25_11965	COG0628	permease
K9D25_11985	COG2814	Major facilitator Superfamily
K9D25_12015	COG0671	phosphoesterase, PA-phosphatase related
K9D25_12020	COG4191	Histidine kinase
K9D25_12020	COG0784	Response regulator, receiver
K9D25_12035	COG2022	thiamine diphosphate biosynthetic process
K9D25_12105	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
K9D25_12110	COG0500	methyltransferase
K9D25_12125	COG0514	ATP-dependent DNA helicase (RecQ)
K9D25_12135	COG1492	cobalamin metabolic process
K9D25_12205	COG1797	cobyrinic acid a,c-diamide synthase activity
K9D25_12215	COG0058	SHG alpha-glucan phosphorylase activity
K9D25_12220	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
K9D25_12230	COG0297	glycogen (starch) synthase activity
K9D25_12250	COG0725	ABC transporter, periplasmic molybdate-binding protein
K9D25_12255	COG4149	molybdate abc transporter
K9D25_12295	COG4214	carbohydrate transport
K9D25_12300	COG4213	ABC transporter substrate-binding protein
K9D25_12305	COG1609	Transcriptional regulator
K9D25_12310	COG1070	Carbohydrate kinase
K9D25_12315	COG2115	Belongs to the xylose isomerase family
K9D25_12325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K9D25_12330	COG1024	Enoyl-CoA hydratase
K9D25_12335	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K9D25_12340	COG1802	Transcriptional regulator
K9D25_12345	COG1733	regulation of RNA biosynthetic process
K9D25_12350	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
K9D25_12355	COG1802	Transcriptional regulator
K9D25_12360	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
K9D25_12365	COG0277	FAD linked oxidase domain protein
K9D25_12365	COG0247	lactate metabolic process
K9D25_12370	COG3181	Tripartite tricarboxylate transporter family receptor
K9D25_12400	COG0494	nUDIX hydrolase
K9D25_12420	COG2188	Transcriptional regulator
K9D25_12425	COG3624	Phosphonate C-P lyase system protein PhnG
K9D25_12435	COG3626	phosphonate metabolism
K9D25_12445	COG4107	phosphonate C-P lyase system protein PhnK
K9D25_12450	COG4778	phosphonate C-P lyase system protein PhnL
K9D25_12455	COG3454	Phosphonate metabolism
K9D25_12460	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
K9D25_12475	COG0482	sulfurtransferase activity
K9D25_12500	COG0435	Glutathione S-transferase
K9D25_12535	COG0714	Associated with various cellular activities
K9D25_12545	COG0494	nUDIX hydrolase
K9D25_12555	COG0617	tRNA 3'-terminal CCA addition
K9D25_12560	COG2857	Cytochrome c1
K9D25_12560	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K9D25_12565	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
K9D25_12565	COG2857	Cytochrome c1
K9D25_12570	COG0723	plastoquinol--plastocyanin reductase activity
K9D25_12575	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
K9D25_12590	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K9D25_12595	COG1132	(ABC) transporter
K9D25_12605	COG0408	coproporphyrinogen oxidase activity
K9D25_12630	COG0012	GTP binding
K9D25_12635	COG0193	aminoacyl-tRNA hydrolase activity
K9D25_12640	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
K9D25_12650	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
K9D25_12675	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
K9D25_12700	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
K9D25_12705	COG2205	protein histidine kinase activity
K9D25_12710	COG0745	RESPONSE REGULATOR receiver
K9D25_12715	COG1846	Transcriptional regulator
K9D25_12720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K9D25_12725	COG0314	molybdopterin synthase activity
K9D25_12735	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
K9D25_12740	COG0322	excinuclease ABC activity
K9D25_12755	COG0318	PFAM AMP-dependent synthetase and ligase
K9D25_12780	COG1028	Short-chain dehydrogenase reductase Sdr
K9D25_12785	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
K9D25_12790	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
K9D25_12795	COG0625	glutathione transferase activity
K9D25_12800	COG1278	Cold shock
K9D25_12805	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
K9D25_12830	COG1335	isochorismatase
K9D25_12840	COG0556	nucleotide-excision repair
K9D25_12865	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
K9D25_12870	COG0662	Cupin 2, conserved barrel domain protein
K9D25_12885	COG1671	Belongs to the UPF0178 family
K9D25_12890	COG0405	Gamma-glutamyltransferase
K9D25_12930	COG2198	Histidine kinase
K9D25_12930	COG2205	protein histidine kinase activity
K9D25_12930	COG0784	Response regulator, receiver
K9D25_12935	COG0745	RESPONSE REGULATOR receiver
K9D25_12945	COG1012	belongs to the aldehyde dehydrogenase family
K9D25_12950	COG3284	Transcriptional regulator
K9D25_12960	COG1320	monovalent cation:proton antiporter activity
K9D25_12965	COG2212	antiporter activity
K9D25_12970	COG1863	multisubunit Na H antiporter MnhE subunit
K9D25_12975	COG0651	ATP synthesis coupled electron transport
K9D25_12980	COG1006	Multisubunit Na H antiporter MnhC subunit
K9D25_12985	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K9D25_12985	COG2111	Na H antiporter
K9D25_13010	COG2824	Alkylphosphonate utilization operon protein PhnA
K9D25_13015	COG0129	dihydroxy-acid dehydratase activity
K9D25_13025	COG0477	Major facilitator Superfamily
K9D25_13040	COG2968	Membrane
K9D25_13060	COG2133	pyrroloquinoline quinone binding
K9D25_13070	COG0625	glutathione transferase activity
K9D25_13075	COG0436	Aminotransferase
K9D25_13085	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K9D25_13095	COG0583	DNA-binding transcription factor activity
K9D25_13100	COG0492	ferredoxin-NADP+ reductase activity
K9D25_13105	COG1522	sequence-specific DNA binding
K9D25_13110	COG1442	glycosyl transferase family 8
K9D25_13125	COG0438	transferase activity, transferring glycosyl groups
K9D25_13130	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K9D25_13135	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
K9D25_13155	COG0505	Belongs to the CarA family
K9D25_13175	COG0358	DNA primase activity
K9D25_13180	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
K9D25_13205	COG3258	Cytochrome c
K9D25_13210	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
K9D25_13220	COG1877	trehalose-phosphatase activity
K9D25_13225	COG0488	(ABC) transporter
K9D25_13230	COG4106	trans-aconitate 2-methyltransferase activity
K9D25_13245	COG2890	protein-(glutamine-N5) methyltransferase activity
K9D25_13280	COG1376	ErfK ybiS ycfS ynhG family protein
K9D25_13290	COG2226	methyltransferase
K9D25_13305	COG2852	Protein conserved in bacteria
K9D25_13325	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
K9D25_13330	COG0154	amidase activity
K9D25_13335	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
K9D25_13340	COG0384	phenazine biosynthesis protein PhzF
K9D25_13350	COG1744	ABC transporter substrate-binding protein PnrA-like
K9D25_13355	COG3845	ABC transporter
K9D25_13365	COG1079	Belongs to the binding-protein-dependent transport system permease family
K9D25_13370	COG0402	S-adenosylhomocysteine deaminase activity
K9D25_13380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K9D25_13385	COG0481	GTPase activity
K9D25_13390	COG3422	double-strand break repair
K9D25_13405	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
K9D25_13430	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K9D25_13455	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
K9D25_13465	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K9D25_13515	COG1902	pentaerythritol trinitrate reductase activity
K9D25_13520	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
K9D25_13530	COG0673	inositol 2-dehydrogenase activity
K9D25_13540	COG0728	peptidoglycan biosynthetic process
K9D25_13545	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9D25_13560	COG0633	Ferredoxin
K9D25_13565	COG3768	UPF0283 membrane protein
K9D25_13570	COG3106	COG3106 Predicted ATPase
K9D25_13600	COG0166	Belongs to the GPI family
K9D25_13605	COG0033	Phosphoglucomutase
K9D25_13610	COG1846	Transcriptional regulator
K9D25_13615	COG0783	Belongs to the Dps family
K9D25_13635	COG1028	Short-chain dehydrogenase reductase Sdr
K9D25_13655	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
K9D25_13670	COG1832	CoA-binding protein
K9D25_13675	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
K9D25_13680	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
K9D25_13695	COG0174	glutamine synthetase
K9D25_13700	COG0347	Belongs to the P(II) protein family
K9D25_13705	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
K9D25_13705	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
K9D25_13715	COG0544	peptidyl-prolyl cis-trans isomerase activity
K9D25_13720	COG0740	serine-type endopeptidase activity
K9D25_13725	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
K9D25_13730	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
K9D25_13735	COG0776	regulation of translation
K9D25_13760	COG4372	Transposase
K9D25_13795	COG0546	phosphoglycolate phosphatase activity
K9D25_13805	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
K9D25_13815	COG0251	oxidation-reduction process
K9D25_13845	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
K9D25_13850	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K9D25_13855	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
K9D25_13890	COG0538	isocitrate dehydrogenase activity
K9D25_13900	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
K9D25_13910	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
K9D25_13920	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
K9D25_13930	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K9D25_13935	COG0047	phosphoribosylformylglycinamidine synthase activity
K9D25_13940	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
K9D25_13945	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
K9D25_13960	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
K9D25_13990	COG4176	ABC-type proline glycine betaine transport system permease component
K9D25_13995	COG0517	IMP dehydrogenase activity
K9D25_13995	COG4175	Glycine betaine
K9D25_14000	COG3191	aminopeptidase activity
K9D25_14005	COG0785	Cytochrome C biogenesis protein
K9D25_14010	COG0683	leucine binding
K9D25_14040	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K9D25_14045	COG2081	HI0933 family
K9D25_14095	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
K9D25_14105	COG1396	sequence-specific DNA binding
K9D25_14110	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K9D25_14115	COG0438	transferase activity, transferring glycosyl groups
K9D25_14135	COG3909	cytochrome
K9D25_14145	COG0697	spore germination
K9D25_14155	COG0351	phosphomethylpyrimidine kinase
K9D25_14160	COG2814	Major facilitator Superfamily
K9D25_14165	COG4948	Mandelate Racemase Muconate Lactonizing
K9D25_14170	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
K9D25_14175	COG1127	ABC transporter
K9D25_14185	COG3218	ABC-type transport auxiliary lipoprotein component
K9D25_14185	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
K9D25_14190	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
K9D25_14195	COG0459	protein refolding
K9D25_14200	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
K9D25_14205	COG5425	PFAM Usg family protein
K9D25_14210	COG3932	Exopolysaccharide synthesis, ExoD
K9D25_14220	COG1028	Short-chain dehydrogenase reductase Sdr
K9D25_14230	COG1305	Transglutaminase-like
K9D25_14240	COG1280	lysine exporter protein (LysE YggA)
K9D25_14245	COG2308	Evidence 4 Homologs of previously reported genes of
K9D25_14250	COG1058	Belongs to the CinA family
K9D25_14250	COG1546	Belongs to the CinA family
K9D25_14255	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
K9D25_14290	COG1177	transmembrane transport
K9D25_14295	COG1176	ABC-type spermidine putrescine transport system, permease component I
K9D25_14305	COG3842	ATPase activity
K9D25_14320	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
K9D25_14335	COG1289	transmembrane transporter activity
K9D25_14345	COG0076	glutamate decarboxylase activity
K9D25_14350	COG0506	proline dehydrogenase activity
K9D25_14350	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
K9D25_14350	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
K9D25_14355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K9D25_14390	COG3657	addiction module killer protein
K9D25_14395	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K9D25_14430	COG0516	GMP reductase activity
K9D25_14430	COG0517	IMP dehydrogenase activity
K9D25_14435	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
K9D25_14440	COG0302	gtp cyclohydrolase
K9D25_14455	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
K9D25_14460	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
K9D25_14470	COG2208	phosphoserine phosphatase activity
K9D25_14470	COG2770	Histidine kinase
K9D25_14500	COG2233	PERMEase
K9D25_14505	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K9D25_14510	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K9D25_14525	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
K9D25_14585	COG0375	protein maturation
K9D25_14595	COG2204	response regulator
K9D25_14650	COG1132	(ABC) transporter
K9D25_14660	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K9D25_14675	COG0525	valine-tRNA ligase activity
K9D25_14690	COG0129	dihydroxy-acid dehydratase activity
K9D25_14710	COG0316	Belongs to the HesB IscA family
K9D25_14715	COG0232	Belongs to the dGTPase family. Type 2 subfamily
K9D25_14720	COG0018	arginyl-trna synthetase
K9D25_14730	COG1472	Belongs to the glycosyl hydrolase 3 family
K9D25_14735	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
K9D25_14740	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
K9D25_14745	COG3842	ATPase activity
K9D25_14750	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K9D25_14755	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
K9D25_14760	COG0805	protein transport
K9D25_14765	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
K9D25_14770	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
K9D25_14775	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
K9D25_14795	COG1862	Preprotein translocase
K9D25_14800	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
K9D25_14820	COG2877	3-deoxy-8-phosphooctulonate synthase activity
K9D25_14830	COG0628	permease
K9D25_14845	COG1115	amino acid carrier protein
K9D25_14855	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K9D25_14860	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K9D25_14865	COG0649	NAD binding
K9D25_14870	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
K9D25_14875	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
K9D25_14885	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
K9D25_14895	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
K9D25_14905	COG0713	ATP synthesis coupled electron transport
K9D25_14920	COG1007	ATP synthesis coupled electron transport
K9D25_14935	COG0346	lactoylglutathione lyase activity
K9D25_14945	COG0442	prolyl-tRNA aminoacylation
K9D25_14955	COG1136	(ABC) transporter
K9D25_14970	COG0052	Belongs to the universal ribosomal protein uS2 family
K9D25_14975	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
K9D25_14980	COG0528	UMP kinase activity
K9D25_14985	COG0233	cytoplasmic translational termination
K9D25_14990	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
K9D25_15000	COG0750	zinc metalloprotease
K9D25_15005	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
K9D25_15010	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9D25_15015	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K9D25_15020	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9D25_15025	COG3494	Protein of unknown function (DUF1009)
K9D25_15030	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
K9D25_15035	COG0372	Belongs to the citrate synthase family
K9D25_15040	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K9D25_15050	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
K9D25_15055	COG1802	Transcriptional regulator
K9D25_15065	COG0303	'Molybdopterin
K9D25_15070	COG0315	cyclic pyranopterin monophosphate synthase activity
K9D25_15075	COG0134	indole-3-glycerol-phosphate synthase activity
K9D25_15080	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
K9D25_15090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
K9D25_15100	COG0149	triose-phosphate isomerase activity
K9D25_15110	COG0504	CTP synthase activity
K9D25_15145	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
K9D25_15150	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
K9D25_15155	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
K9D25_15160	COG0148	phosphopyruvate hydratase activity
K9D25_15175	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K9D25_15185	COG0508	dehydrogenase complex catalyzes the overall conversion of
K9D25_15185	COG0022	dehydrogenase e1 component
K9D25_15190	COG0508	dehydrogenase complex catalyzes the overall conversion of
K9D25_15195	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
K9D25_15205	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
K9D25_15210	COG2867	negative regulation of translational initiation
K9D25_15230	COG1546	Belongs to the CinA family
K9D25_15235	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
K9D25_15235	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
K9D25_15250	COG2204	response regulator
K9D25_15255	COG5000	phosphorelay sensor kinase activity
K9D25_15260	COG2204	response regulator
K9D25_15265	COG0569	domain protein
K9D25_15270	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
K9D25_15280	COG1923	regulation of RNA biosynthetic process
K9D25_15285	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
K9D25_15290	COG3956	TIGRFAM MazG family protein
K9D25_15295	COG0321	lipoyl(octanoyl) transferase activity
K9D25_15295	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
K9D25_15300	COG0084	hydrolase, TatD family'
K9D25_15310	COG0470	DNA polymerase III
K9D25_15315	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
K9D25_15320	COG1686	Belongs to the peptidase S11 family
K9D25_15330	COG2197	response regulator
K9D25_15345	COG4993	Dehydrogenase
K9D25_15350	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K9D25_15365	COG0714	Associated with various cellular activities
K9D25_15420	COG0840	transmembrane signaling receptor activity
K9D25_15425	COG1879	ABC-type sugar transport system periplasmic component
K9D25_15430	COG1129	ABC transporter
K9D25_15435	COG1172	Belongs to the binding-protein-dependent transport system permease family
K9D25_15440	COG1172	Belongs to the binding-protein-dependent transport system permease family
K9D25_15470	COG0129	dihydroxy-acid dehydratase activity
K9D25_15475	COG3386	PFAM SMP-30 Gluconolaconase
K9D25_15485	COG0800	Aldolase
K9D25_15490	COG4213	ABC transporter substrate-binding protein
K9D25_15500	COG4214	carbohydrate transport
K9D25_15515	COG0277	FAD linked oxidase domain protein
K9D25_15520	COG2186	Transcriptional regulator
K9D25_15535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K9D25_15540	COG1012	belongs to the aldehyde dehydrogenase family
K9D25_15560	COG0395	ABC-type sugar transport system, permease component
K9D25_15565	COG3842	ATPase activity
K9D25_15575	COG1262	PFAM Formylglycine-generating sulfatase enzyme
K9D25_15590	COG1349	DNA-binding transcription factor activity
K9D25_15595	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
K9D25_15605	COG1129	ABC transporter
K9D25_15635	COG0850	regulation of cytokinetic process
K9D25_15645	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
K9D25_15665	COG0629	single-stranded DNA binding
K9D25_15955	COG4221	oxidoreductase activity
K9D25_15980	COG2329	Antibiotic biosynthesis monooxygenase
K9D25_15985	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
K9D25_15995	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K9D25_16005	COG1079	Belongs to the binding-protein-dependent transport system permease family
K9D25_16010	COG1172	Belongs to the binding-protein-dependent transport system permease family
K9D25_16015	COG3845	ABC transporter
K9D25_16025	COG1183	phosphatidylcholine synthase activity
K9D25_16030	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
K9D25_16035	COG0679	Auxin Efflux Carrier
K9D25_16050	COG4166	transmembrane transport
K9D25_16060	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
K9D25_16070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
K9D25_16075	COG2832	Protein of unknown function (DUF454)
K9D25_16080	COG0746	molybdenum cofactor guanylyltransferase activity
K9D25_16110	COG0655	NAD(P)H dehydrogenase (quinone) activity
K9D25_16115	COG0343	queuine tRNA-ribosyltransferase activity
K9D25_16120	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
K9D25_16135	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
K9D25_16145	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K9D25_16150	COG2095	MarC family integral membrane protein
K9D25_16155	COG0629	single-stranded DNA binding
K9D25_16165	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K9D25_16170	COG1612	heme a metabolic process
K9D25_16270	COG4626	Terminase
K9D25_16270	COG1802	Transcriptional regulator
K9D25_16310	COG0778	Nitroreductase
K9D25_16315	COG1012	belongs to the aldehyde dehydrogenase family
K9D25_16320	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
K9D25_16330	COG0776	regulation of translation
K9D25_16335	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
K9D25_16340	COG0416	fatty acid biosynthetic process
K9D25_16370	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
K9D25_16375	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K9D25_16380	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
K9D25_16390	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K9D25_16390	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
K9D25_16395	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
K9D25_16400	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
K9D25_16420	COG1024	Enoyl-CoA hydratase
K9D25_16430	COG0113	porphobilinogen synthase activity
K9D25_16440	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
K9D25_16450	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
K9D25_16460	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
K9D25_16465	COG1381	Involved in DNA repair and RecF pathway recombination
K9D25_16470	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
K9D25_16475	COG0571	ribonuclease III activity
K9D25_16485	COG0736	holo-[acyl-carrier-protein] synthase activity
K9D25_16490	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
K9D25_16495	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
K9D25_16510	COG1758	RNA polymerase activity
K9D25_16520	COG1573	uracil-dna glycosylase
K9D25_16525	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
K9D25_16530	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
K9D25_16535	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
K9D25_16540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
K9D25_16585	COG0828	Belongs to the bacterial ribosomal protein bS21 family
K9D25_16610	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
K9D25_16660	COG0765	amino acid transport
K9D25_16665	COG0765	amino acid transport
K9D25_16670	COG1126	abc transporter atp-binding protein
K9D25_16680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K9D25_16695	COG4774	siderophore transport
K9D25_16710	COG2819	hydrolase of the alpha beta superfamily
K9D25_16715	COG1120	ATPase activity
K9D25_16725	COG2515	1-aminocyclopropane-1-carboxylate deaminase
K9D25_16740	COG4521	taurine ABC transporter
K9D25_16745	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
K9D25_16750	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9D25_16755	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K9D25_16765	COG2204	response regulator
K9D25_16770	COG4191	Histidine kinase
K9D25_16775	COG1301	dicarboxylic acid transport
K9D25_16810	COG3842	ATPase activity
K9D25_16815	COG1176	ABC-type spermidine putrescine transport system, permease component I
K9D25_16820	COG1177	transmembrane transport
K9D25_16830	COG0747	negative chemotaxis
K9D25_16835	COG4172	Belongs to the ABC transporter superfamily
K9D25_16840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K9D25_16845	COG0601	transmembrane transport
K9D25_16850	COG2267	carboxylic ester hydrolase activity
K9D25_16855	COG2197	response regulator
K9D25_16865	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K9D25_16875	COG1230	cation diffusion facilitator family transporter
K9D25_16880	COG3034	peptidoglycan biosynthetic process
K9D25_16895	COG4303	Ethanolamine ammonia lyase large subunit
K9D25_16910	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K9D25_16925	COG0477	Major facilitator Superfamily
K9D25_16930	COG0523	cobalamin synthesis protein
K9D25_16935	COG0784	Response regulator, receiver
K9D25_16935	COG4191	Histidine kinase
K9D25_16940	COG0828	Belongs to the bacterial ribosomal protein bS21 family
K9D25_16945	COG1278	Cold shock
K9D25_16965	COG0251	oxidation-reduction process
K9D25_17010	COG0456	acetyltransferase
K9D25_17020	COG3284	Transcriptional regulator
K9D25_17025	COG3199	ATP-NAD kinase
K9D25_17030	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
K9D25_17035	COG0022	dehydrogenase e1 component
K9D25_17040	COG0596	Alpha beta hydrolase
K9D25_17040	COG0508	dehydrogenase complex catalyzes the overall conversion of
K9D25_17050	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
K9D25_17055	COG1063	alcohol dehydrogenase
K9D25_17065	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
K9D25_17070	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
K9D25_17075	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
K9D25_17080	COG2205	protein histidine kinase activity
K9D25_17085	COG0745	RESPONSE REGULATOR receiver
K9D25_17100	COG3655	Transcriptional regulator
K9D25_17105	COG0582	viral genome integration into host DNA
K9D25_17190	COG4626	Terminase
K9D25_17190	COG1802	Transcriptional regulator
K9D25_17230	COG0625	glutathione transferase activity
K9D25_17245	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K9D25_17250	COG1620	l-lactate permease
K9D25_17265	COG0287	Prephenate dehydrogenase
K9D25_17265	COG1605	Chorismate mutase
K9D25_17270	COG0154	amidase activity
K9D25_17275	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
K9D25_17295	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
K9D25_17300	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
K9D25_17310	COG0540	Belongs to the ATCase OTCase family
K9D25_17315	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
K9D25_17320	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
K9D25_17325	COG0758	DNA mediated transformation
K9D25_17335	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
K9D25_17340	COG0477	Major facilitator Superfamily
K9D25_17345	COG0557	exoribonuclease II activity
K9D25_17365	COG0267	Belongs to the bacterial ribosomal protein bL33 family
K9D25_17370	COG0784	Response regulator, receiver
K9D25_17380	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K9D25_17425	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
K9D25_17435	COG1686	Belongs to the peptidase S11 family
K9D25_17440	COG0484	heat shock protein binding
K9D25_17450	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
K9D25_17485	COG2239	Acts as a magnesium transporter
K9D25_17490	COG1254	Belongs to the acylphosphatase family
K9D25_17495	COG0321	lipoyl(octanoyl) transferase activity
K9D25_17515	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
K9D25_17520	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
K9D25_17530	COG0203	ribosomal protein L17
K9D25_17535	COG0202	RNA polymerase activity
K9D25_17540	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
K9D25_17545	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
K9D25_17550	COG0563	adenylate kinase activity
K9D25_17555	COG0201	protein transport
K9D25_17560	COG0200	Binds to the 23S rRNA
K9D25_17565	COG1841	ribosomal large subunit assembly
K9D25_17570	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
K9D25_17575	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
K9D25_17580	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
K9D25_17585	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
K9D25_17590	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
K9D25_17595	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
K9D25_17600	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
K9D25_17605	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
K9D25_17610	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
K9D25_17615	COG0255	Belongs to the universal ribosomal protein uL29 family
K9D25_17620	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
K9D25_17625	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
K9D25_17630	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
K9D25_17635	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
K9D25_17640	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
K9D25_17645	COG0089	rRNA binding
K9D25_17650	COG0088	Forms part of the polypeptide exit tunnel
K9D25_17655	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
K9D25_17660	COG0051	transcription antitermination factor activity, RNA binding
K9D25_17665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K9D25_17670	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
K9D25_17675	COG0049	tRNA binding
K9D25_17680	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
K9D25_17685	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
K9D25_17690	COG0085	RNA polymerase activity
K9D25_17695	COG0222	ribosome binding
K9D25_17700	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
K9D25_17705	COG0081	regulation of translation
K9D25_17710	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
K9D25_17720	COG0693	protein deglycase activity
K9D25_17730	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
K9D25_17740	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
K9D25_17755	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
K9D25_17765	COG0251	oxidation-reduction process
K9D25_17790	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
K9D25_17795	COG1253	flavin adenine dinucleotide binding
K9D25_17800	COG1840	ABC-type Fe3 transport system, periplasmic component
K9D25_17805	COG3842	ATPase activity
K9D25_17815	COG1177	transmembrane transport
K9D25_17825	COG1234	tRNA 3'-trailer cleavage
K9D25_17835	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
K9D25_17855	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
K9D25_17865	COG1376	ErfK ybiS ycfS ynhG family protein
K9D25_17865	COG1388	LysM domain
K9D25_17875	COG0729	surface antigen
K9D25_17885	COG0300	oxidoreductase activity
K9D25_17890	COG0415	Belongs to the DNA photolyase family
K9D25_17900	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
K9D25_17905	COG2897	thiosulfate sulfurtransferase activity
K9D25_17910	COG1126	abc transporter atp-binding protein
K9D25_17915	COG0765	amino acid transport
K9D25_17920	COG4597	amino acid ABC transporter
K9D25_17925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K9D25_17930	COG0626	cystathionine gamma-synthase activity
K9D25_17940	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
K9D25_17945	COG0830	nickel cation binding
K9D25_17955	COG0804	urea catabolic process
K9D25_17960	COG0832	Belongs to the urease beta subunit family
K9D25_17960	COG0831	urea catabolic process
K9D25_17965	COG0829	nickel cation binding
K9D25_17970	COG3842	ATPase activity
K9D25_18075	COG1494	fructose-1,6-bisphosphatase
K9D25_18085	COG0436	Aminotransferase
K9D25_18095	COG3243	poly(R)-hydroxyalkanoic acid synthase
K9D25_18100	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
K9D25_18110	COG0187	DNA topoisomerase II activity
K9D25_18115	COG1280	lysine exporter protein (LysE YggA)
K9D25_18120	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
K9D25_18125	COG0513	Belongs to the DEAD box helicase family
K9D25_18130	COG0668	transmembrane transport
K9D25_18140	COG0316	Belongs to the HesB IscA family
K9D25_18145	COG0346	lactoylglutathione lyase activity
K9D25_18150	COG2151	metal-sulfur cluster biosynthetic enzyme
K9D25_18155	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
K9D25_18160	COG0719	Fe-S assembly protein
K9D25_18165	COG0396	ATPase activity
K9D25_18170	COG0719	Fe-S assembly protein
K9D25_18175	COG1104	cysteine desulfurase activity
K9D25_18180	COG2945	thiolester hydrolase activity
K9D25_18190	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
K9D25_18195	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
K9D25_18205	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
K9D25_18220	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K9D25_18225	COG0860	N-Acetylmuramoyl-L-alanine amidase
K9D25_18230	COG1530	ribonuclease E activity
K9D25_18240	COG0702	epimerase
K9D25_18250	COG0436	Aminotransferase
K9D25_18265	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
K9D25_18270	COG0511	ligase activity, forming carbon-carbon bonds
K9D25_18275	COG0439	Biotin carboxylase
K9D25_18295	COG2814	Major facilitator Superfamily
K9D25_18300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
K9D25_18310	COG1522	sequence-specific DNA binding
K9D25_18315	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K9D25_18320	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9D25_18355	COG0714	Associated with various cellular activities
K9D25_18360	COG3851	Histidine kinase
K9D25_18375	COG0326	Molecular chaperone. Has ATPase activity
K9D25_18410	COG3046	protein related to deoxyribodipyrimidine photolyase
K9D25_18425	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
K9D25_18450	COG1802	Transcriptional regulator
K9D25_18480	COG0559	Belongs to the binding-protein-dependent transport system permease family
K9D25_18500	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K9D25_18505	COG0693	protein deglycase activity
K9D25_18510	COG1879	ABC-type sugar transport system periplasmic component
K9D25_18515	COG1172	Belongs to the binding-protein-dependent transport system permease family
K9D25_18520	COG1129	ABC transporter
K9D25_18545	COG1278	Cold shock
K9D25_18550	COG1278	Cold shock
K9D25_18555	COG0384	phenazine biosynthesis protein PhzF
K9D25_18565	COG0281	malic enzyme
K9D25_18565	COG0280	phosphate acetyltransferase
K9D25_18575	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
K9D25_18585	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
K9D25_18590	COG1181	Belongs to the D-alanine--D-alanine ligase family
K9D25_18595	COG0248	Ppx GppA phosphatase
K9D25_18600	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
K9D25_18610	COG0628	permease
K9D25_18620	COG3135	benzoate transporter
K9D25_18625	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
K9D25_18630	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
K9D25_18635	COG2376	Dihydroxyacetone kinase
K9D25_18640	COG2376	Dihydroxyacetone kinase
K9D25_18645	COG1172	Belongs to the binding-protein-dependent transport system permease family
K9D25_18650	COG1129	ABC transporter
K9D25_18675	COG0667	Aldo Keto reductase
K9D25_18715	COG0243	molybdopterin cofactor binding
K9D25_18720	COG0861	Integral membrane protein TerC family
K9D25_18725	COG0861	Integral membrane protein TerC family
K9D25_18730	COG0105	UTP biosynthetic process
K9D25_18750	COG0488	(ABC) transporter
K9D25_18765	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
K9D25_18795	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
K9D25_18800	COG0194	GDP metabolic process
K9D25_18805	COG1561	YicC-like family, N-terminal region
K9D25_18810	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
K9D25_18815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K9D25_18820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K9D25_18830	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
K9D25_18835	COG0360	Binds together with S18 to 16S ribosomal RNA
K9D25_18840	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
K9D25_18850	COG0359	binds to the 23S rRNA
K9D25_18855	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K9D25_18860	COG0305	Participates in initiation and elongation during chromosome replication
K9D25_18865	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
K9D25_18875	COG1286	toxin biosynthetic process
K9D25_18880	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
K9D25_18890	COG0300	oxidoreductase activity
K9D25_18900	COG1160	GTP binding
K9D25_18915	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
K9D25_18935	COG1393	Belongs to the ArsC family
K9D25_18965	COG0535	radical SAM domain protein
K9D25_18970	COG0535	radical SAM domain protein
K9D25_18975	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
K9D25_18995	COG5002	protein histidine kinase activity
K9D25_19005	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
K9D25_19010	COG1116	anion transmembrane transporter activity
K9D25_19045	COG1131	(ABC) transporter
K9D25_19090	COG2272	Belongs to the type-B carboxylesterase lipase family
K9D25_19100	COG0288	reversible hydration of carbon dioxide
K9D25_19115	COG4191	Histidine kinase
K9D25_19115	COG0784	Response regulator, receiver
K9D25_19125	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
K9D25_19130	COG3002	Belongs to the UPF0753 family
K9D25_19135	COG0519	Catalyzes the synthesis of GMP from XMP
K9D25_19135	COG0518	GMP synthase (glutamine-hydrolyzing) activity
K9D25_19140	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
K9D25_19140	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
K9D25_19155	COG0477	Major facilitator Superfamily
K9D25_19160	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
K9D25_19175	COG3468	outer membrane autotransporter barrel domain protein
K9D25_19190	COG4974	Belongs to the 'phage' integrase family
K9D25_19245	COG4953	penicillin-binding protein 1C
K9D25_19255	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
K9D25_19260	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
K9D25_19265	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K9D25_19270	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
K9D25_19275	COG1028	Short-chain dehydrogenase reductase Sdr
K9D25_19280	COG0604	alcohol dehydrogenase
K9D25_19280	COG3321	synthase
K9D25_19285	COG1560	Kdo2-lipid A biosynthetic process
K9D25_19295	COG0174	glutamine synthetase
K9D25_19305	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
K9D25_19335	COG4221	oxidoreductase activity
K9D25_19350	COG1183	phosphatidylcholine synthase activity
K9D25_19355	COG0688	phosphatidylethanolamine metabolic process
K9D25_19360	COG5265	(ABC) transporter
K9D25_19380	COG0215	cysteine-tRNA ligase activity
K9D25_19390	COG3045	CreA protein
K9D25_19400	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
K9D25_19400	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
K9D25_19405	COG0679	Auxin Efflux Carrier
K9D25_19420	COG1733	regulation of RNA biosynthetic process
K9D25_19445	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
K9D25_19475	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
K9D25_19485	COG0546	phosphoglycolate phosphatase activity
K9D25_19500	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
K9D25_19500	COG2755	lipolytic protein G-D-S-L family
K9D25_19505	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
K9D25_19505	COG2755	lipolytic protein G-D-S-L family
K9D25_19510	COG1376	ErfK ybiS ycfS ynhG family protein
K9D25_19525	COG2814	Major facilitator Superfamily
K9D25_19535	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
K9D25_19540	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
K9D25_19545	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
K9D25_19550	COG0489	protein tyrosine kinase activity
K9D25_19555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
K9D25_19570	COG1573	uracil-dna glycosylase
K9D25_19575	COG1525	nuclease
K9D25_19580	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
K9D25_19585	COG0778	Nitroreductase
K9D25_19590	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
K9D25_19605	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
K9D25_19610	COG0730	response to heat
K9D25_19650	COG1959	2 iron, 2 sulfur cluster binding
K9D25_19660	COG4191	Histidine kinase
K9D25_19665	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
K9D25_19700	COG0310	cobalt ion transport
K9D25_19720	COG1250	3-hydroxyacyl-CoA dehydrogenase
K9D25_19720	COG0824	Thioesterase
K9D25_19725	COG3246	L-lysine catabolic process to acetate
K9D25_19740	COG0483	inositol monophosphate 1-phosphatase activity
K9D25_19750	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
K9D25_19755	COG1175	transmembrane transport
K9D25_19780	COG1063	alcohol dehydrogenase
K9D25_19790	COG1069	ribulokinase activity
K9D25_19815	COG3685	Protein conserved in bacteria
K9D25_19845	COG1175	transmembrane transport
K9D25_19860	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
K9D25_19865	COG1275	C4-dicarboxylate transporter malic acid transport protein
K9D25_19880	COG0640	Transcriptional regulator
K9D25_19885	COG3453	Protein conserved in bacteria
K9D25_19885	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
K9D25_19895	COG0596	Alpha beta hydrolase
K9D25_19925	COG1028	Short-chain dehydrogenase reductase Sdr
K9D25_19935	COG0473	3-isopropylmalate dehydrogenase activity
K9D25_19945	COG2186	Transcriptional regulator
K9D25_19950	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
K9D25_19960	COG0473	3-isopropylmalate dehydrogenase activity
K9D25_19965	COG2079	MmgE PrpD family protein
K9D25_19970	COG0625	glutathione transferase activity
K9D25_19980	COG1396	sequence-specific DNA binding
K9D25_19980	COG3800	Transcriptional regulator
K9D25_19990	COG2224	Isocitrate lyase
K9D25_19995	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K9D25_20010	COG1674	ftsk spoiiie
K9D25_20030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K9D25_20040	COG1959	2 iron, 2 sulfur cluster binding
K9D25_20050	COG0747	negative chemotaxis
K9D25_20055	COG0601	transmembrane transport
K9D25_20060	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K9D25_20065	COG0444	Belongs to the ABC transporter superfamily
K9D25_20070	COG4608	Belongs to the ABC transporter superfamily
K9D25_20080	COG0848	biopolymer transport protein
K9D25_20090	COG0277	FAD linked oxidase domain protein
K9D25_20095	COG3609	addiction module antidote protein, CC2985 family
K9D25_20105	COG0488	(ABC) transporter
K9D25_20145	COG2239	Acts as a magnesium transporter
K9D25_20155	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
K9D25_20160	COG1229	Formylmethanofuran dehydrogenase subunit A
K9D25_20165	COG1029	Formylmethanofuran dehydrogenase, subunit B
K9D25_20170	COG2154	pterin-4-alpha-carbinolamine dehydratase
K9D25_20180	COG0702	epimerase
K9D25_20195	COG1181	Belongs to the D-alanine--D-alanine ligase family
K9D25_20255	COG3047	cAMP biosynthetic process
K9D25_20265	COG1063	alcohol dehydrogenase
K9D25_20310	COG0308	aminopeptidase N
K9D25_20315	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
K9D25_20320	COG2205	protein histidine kinase activity
K9D25_20320	COG2202	Pas domain
K9D25_20325	COG0579	oxidoreductase
K9D25_20330	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
K9D25_20335	COG2205	protein histidine kinase activity
K9D25_20340	COG0745	RESPONSE REGULATOR receiver
K9D25_20350	COG3088	subunit of a heme lyase
K9D25_20355	COG1138	Cytochrome C-type biogenesis protein
K9D25_20360	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
K9D25_20365	COG4235	cytochrome complex assembly
K9D25_20515	COG4695	Portal protein
K9D25_20535	COG3585	molybdate ion transport
K9D25_20545	COG0717	Belongs to the dCTP deaminase family
K9D25_20585	COG1620	l-lactate permease
K9D25_20590	COG1304	FMN binding
K9D25_20595	COG2983	Belongs to the UPF0260 family
K9D25_20600	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
K9D25_20640	COG2166	iron-sulfur cluster assembly
K9D25_20660	COG4957	zinc ion binding
K9D25_20665	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
K9D25_20680	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K9D25_20700	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
K9D25_20705	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
K9D25_20710	COG0433	COG0433 Predicted ATPase
K9D25_20715	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K9D25_20720	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K9D25_20725	COG1703	isobutyryl-CoA mutase activity
K9D25_20730	COG0784	Response regulator, receiver
K9D25_20735	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
K9D25_20750	COG0730	response to heat
K9D25_20795	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
K9D25_20800	COG2375	cellular response to nickel ion
K9D25_20800	COG1132	(ABC) transporter
K9D25_20805	COG3214	Protein conserved in bacteria
K9D25_20810	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
K9D25_20820	COG4178	(ABC) transporter
K9D25_20825	COG3639	organic phosphonate transmembrane transporter activity
K9D25_20830	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
K9D25_20860	COG1573	uracil-dna glycosylase
K9D25_20865	COG1271	oxidase subunit
K9D25_20870	COG1294	oxidase, subunit
K9D25_20875	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
K9D25_20880	COG2095	MarC family integral membrane protein
K9D25_20885	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
K9D25_20895	COG2205	protein histidine kinase activity
K9D25_20910	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
K9D25_20915	COG0459	protein refolding
K9D25_20925	COG1840	ABC-type Fe3 transport system, periplasmic component
K9D25_20940	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
K9D25_20945	COG0612	Peptidase, M16
K9D25_20955	COG3346	SURF1 family
K9D25_20970	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
K9D25_20980	COG0109	protoheme IX farnesyltransferase activity
K9D25_20985	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
K9D25_20990	COG1565	acr, cog1565
K9D25_20990	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
K9D25_21010	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
K9D25_21015	COG1024	Enoyl-CoA hydratase
K9D25_21020	COG0268	Binds directly to 16S ribosomal RNA
K9D25_21070	COG4959	Type IV secretory pathway protease TraF
K9D25_21110	COG3831	ATPase activity
K9D25_21120	COG5489	Protein of unknown function (DUF736)
K9D25_21125	COG5489	Protein of unknown function (DUF736)
K9D25_21160	COG3077	Addiction module antitoxin, RelB DinJ family
K9D25_21210	COG3038	cytochrome b561
K9D25_21275	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
K9D25_21285	COG0625	glutathione transferase activity
K9D25_21290	COG0277	FAD linked oxidase domain protein
K9D25_21320	COG3047	cAMP biosynthetic process
K9D25_21330	COG1063	alcohol dehydrogenase
K9D25_21400	COG4644	lycopene metabolic process
K9D25_21435	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K9D25_21445	COG0395	ABC-type sugar transport system, permease component
K9D25_21465	COG0318	PFAM AMP-dependent synthetase and ligase
K9D25_21470	COG1012	belongs to the aldehyde dehydrogenase family
K9D25_21475	COG0277	FAD linked oxidase domain protein
K9D25_21480	COG0625	glutathione transferase activity
K9D25_21485	COG0277	FAD linked oxidase domain protein
K9D25_21490	COG0277	FAD linked oxidase domain protein
K9D25_21495	COG0247	lactate metabolic process
K9D25_21520	COG1063	alcohol dehydrogenase
K9D25_21545	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
K9D25_21595	COG4644	lycopene metabolic process
K9D25_21625	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
K9D25_21635	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K9D25_21680	COG0640	Transcriptional regulator
K9D25_21685	COG1475	DNA binding
K9D25_21690	COG1192	Involved in chromosome partitioning
K9D25_21700	COG4962	Type ii secretion system protein e
K9D25_21705	COG3838	Conjugal transfer protein Trbc
K9D25_21715	COG3451	type IV secretory pathway VirB4
K9D25_21720	COG5314	conjugation
K9D25_21730	COG3846	protein secretion by the type IV secretion system
K9D25_21735	COG3701	Conjugal transfer protein
K9D25_21770	COG2272	Belongs to the type-B carboxylesterase lipase family
K9D25_21810	COG0667	Aldo Keto reductase
K9D25_21815	COG4221	oxidoreductase activity
K9D25_21825	COG3474	cytochrome
K9D25_21900	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
K9D25_21905	COG2086	electron transfer activity
K9D25_21910	COG2301	Belongs to the HpcH HpaI aldolase family
K9D25_21915	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
K9D25_21945	COG1053	succinate dehydrogenase
K9D25_21950	COG0183	Belongs to the thiolase family
K9D25_21960	COG1250	3-hydroxyacyl-CoA dehydrogenase
K9D25_21965	COG1250	3-hydroxyacyl-CoA dehydrogenase
K9D25_21965	COG1024	Enoyl-CoA hydratase
K9D25_21970	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K9D25_21975	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
K9D25_21980	COG1028	Short-chain dehydrogenase reductase Sdr
K9D25_21985	COG1960	acyl-CoA dehydrogenase activity
K9D25_21990	COG0673	inositol 2-dehydrogenase activity
K9D25_21995	COG1250	3-hydroxyacyl-CoA dehydrogenase
K9D25_22000	COG1024	Enoyl-CoA hydratase
K9D25_22010	COG0318	PFAM AMP-dependent synthetase and ligase
K9D25_22015	COG1028	Short-chain dehydrogenase reductase Sdr
K9D25_22035	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K9D25_22050	COG2948	multi-organism process
K9D25_22090	COG1028	Short-chain dehydrogenase reductase Sdr
K9D25_22105	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
K9D25_22125	COG4647	ligase activity
K9D25_22130	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
K9D25_22135	COG0145	ligase activity
K9D25_22150	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
K9D25_22165	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9D25_22195	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
K9D25_22210	COG0277	FAD linked oxidase domain protein
K9D25_22220	COG2186	Transcriptional regulator
K9D25_22230	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K9D25_22245	COG4172	Belongs to the ABC transporter superfamily
K9D25_22250	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
K9D25_22255	COG0601	transmembrane transport
K9D25_22270	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K9D25_22280	COG0251	oxidation-reduction process
K9D25_22285	COG0583	DNA-binding transcription factor activity
K9D25_22315	COG2814	Major facilitator Superfamily
K9D25_22340	COG2010	Cytochrome c
K9D25_22340	COG1529	Aldehyde oxidase and xanthine dehydrogenase
K9D25_22345	COG2080	2 iron, 2 sulfur cluster binding
K9D25_22350	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
K9D25_22365	COG0583	DNA-binding transcription factor activity
K9D25_22370	COG0583	DNA-binding transcription factor activity
K9D25_22405	COG3831	ATPase activity
K9D25_22425	COG1079	Belongs to the binding-protein-dependent transport system permease family
K9D25_22440	COG3842	ATPase activity
K9D25_22445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
K9D25_22455	COG0830	nickel cation binding
K9D25_22460	COG0831	urea catabolic process
K9D25_22460	COG0832	Belongs to the urease beta subunit family
K9D25_22465	COG0804	urea catabolic process
K9D25_22470	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
K9D25_22475	COG0829	nickel cation binding
K9D25_22490	COG3609	addiction module antidote protein, CC2985 family
K9D25_22500	COG3831	ATPase activity
K9D25_22510	COG1177	transmembrane transport
K9D25_22515	COG3842	ATPase activity
K9D25_22525	COG3284	Transcriptional regulator
K9D25_22530	COG0277	FAD linked oxidase domain protein
K9D25_22535	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
K9D25_22540	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9D25_22550	COG0251	oxidation-reduction process
K9D25_22555	COG2223	nitrite transmembrane transporter activity
K9D25_22560	COG1012	belongs to the aldehyde dehydrogenase family
K9D25_22590	COG0765	amino acid transport
K9D25_22595	COG0765	amino acid transport
K9D25_22600	COG1126	abc transporter atp-binding protein
K9D25_22605	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
K9D25_22610	COG1126	abc transporter atp-binding protein
K9D25_22635	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
K9D25_22640	COG1522	sequence-specific DNA binding
K9D25_22645	COG0242	peptide deformylase activity
K9D25_22650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
K9D25_22660	COG0363	glucosamine-6-phosphate deaminase activity
K9D25_22670	COG3842	ATPase activity
K9D25_22680	COG4208	sulfate ABC transporter
K9D25_22690	COG0246	Mannitol dehydrogenase
K9D25_22695	COG1802	Transcriptional regulator
K9D25_22700	COG2721	sulfolactate sulfo-lyase activity
K9D25_22715	COG0583	DNA-binding transcription factor activity
K9D25_22725	COG1804	L-carnitine dehydratase bile acid-inducible protein F
K9D25_22730	COG1063	alcohol dehydrogenase
K9D25_22735	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
K9D25_22735	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
K9D25_22745	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
K9D25_22750	COG1012	belongs to the aldehyde dehydrogenase family
K9D25_22755	COG0477	Major facilitator Superfamily
K9D25_22765	COG0110	maltose O-acetyltransferase activity
K9D25_22800	COG2084	Dehydrogenase
K9D25_22805	COG0765	amino acid transport
K9D25_22810	COG0765	amino acid transport
K9D25_22835	COG0583	DNA-binding transcription factor activity
K9D25_22845	COG0604	alcohol dehydrogenase
K9D25_22845	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
K9D25_22845	COG3321	synthase
K9D25_22845	COG4221	oxidoreductase activity
K9D25_22870	COG4638	Rieske (2fe-2S)
K9D25_22880	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9D25_22925	COG1732	Glycine betaine
K9D25_22935	COG0517	IMP dehydrogenase activity
K9D25_22935	COG1125	glycine betaine transport
K9D25_22945	COG1174	glycine betaine transport
K9D25_23005	COG3831	ATPase activity
K9D25_23020	COG3549	Plasmid maintenance system killer
K9D25_23030	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
K9D25_23035	COG4139	cobalamin transport
K9D25_23045	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
K9D25_23050	COG4774	siderophore transport
K9D25_23055	COG1309	transcriptional regulator
K9D25_23060	COG0235	Class ii aldolase
K9D25_23065	COG3395	kinase activity
K9D25_23090	COG3181	Tripartite tricarboxylate transporter family receptor
K9D25_23095	COG0583	DNA-binding transcription factor activity
K9D25_23145	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K9D25_23170	COG3742	Toxic component of a toxin-antitoxin (TA) module. An RNase
K9D25_23190	COG1414	Transcriptional regulator
K9D25_23195	COG1475	DNA binding
K9D25_23200	COG1192	Involved in chromosome partitioning
K9D25_23225	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
K9D25_23235	COG4774	siderophore transport
K9D25_23250	COG1120	ATPase activity
K9D25_23255	COG1309	transcriptional regulator
K9D25_23265	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9D25_23300	COG3527	Alpha-acetolactate decarboxylase
K9D25_23310	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9D25_23320	COG2610	gluconate transmembrane transporter activity
K9D25_23340	COG0745	RESPONSE REGULATOR receiver
K9D25_23370	COG4208	sulfate ABC transporter
K9D25_23375	COG1176	ABC-type spermidine putrescine transport system, permease component I
K9D25_23385	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
K9D25_23405	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
K9D25_23415	COG0058	SHG alpha-glucan phosphorylase activity
K9D25_23510	COG1475	DNA binding
K9D25_23575	COG5489	Protein of unknown function (DUF736)
K9D25_23580	COG5489	Protein of unknown function (DUF736)
K9D25_23595	COG0587	DNA-directed DNA polymerase activity
K9D25_23600	COG4974	Belongs to the 'phage' integrase family
K9D25_23605	COG0582	viral genome integration into host DNA
K9D25_23610	COG4974	Belongs to the 'phage' integrase family
K9D25_23625	COG1999	signal sequence binding
K9D25_23645	COG2124	cytochrome p450
K9D25_23650	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
K9D25_23655	COG0785	Cytochrome C biogenesis protein
K9D25_23665	COG0640	Transcriptional regulator
K9D25_23685	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K9D25_23690	COG4191	Histidine kinase
K9D25_23705	COG3547	Transposase (IS116 IS110 IS902 family)
K9D25_23735	COG5489	Protein of unknown function (DUF736)
K9D25_23740	COG5489	Protein of unknown function (DUF736)
K9D25_23780	COG4644	lycopene metabolic process
K9D25_23800	COG0830	nickel cation binding
K9D25_23810	COG0829	nickel cation binding
K9D25_23815	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
K9D25_23820	COG0804	urea catabolic process
K9D25_23825	COG0832	Belongs to the urease beta subunit family
K9D25_23825	COG0831	urea catabolic process
K9D25_23830	COG1129	ABC transporter
K9D25_23900	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
K9D25_23905	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9D25_23910	COG1129	ABC transporter
K9D25_23910	COG0842	Transport permease protein
K9D25_23915	COG0842	Transport permease protein
K9D25_23920	COG4251	negative regulation of phosphorylation
K9D25_23920	COG5001	Diguanylate cyclase
K9D25_23920	COG3706	GGDEF domain
K9D25_23920	COG2203	Gaf domain
K9D25_23935	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
K9D25_23945	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K9D25_23985	COG1192	Involved in chromosome partitioning
K9D25_23990	COG1475	DNA binding
K9D25_23995	COG1414	Transcriptional regulator
K9D25_24000	COG0629	single-stranded DNA binding
K9D25_24015	COG1414	Transcriptional regulator
K9D25_24025	COG1192	Involved in chromosome partitioning
K9D25_24050	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9D25_24070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
K9D25_24075	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
K9D25_24145	COG2197	response regulator
K9D25_24155	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
K9D25_24160	COG2948	multi-organism process
K9D25_24165	COG3504	Conjugal transfer protein
K9D25_24175	COG3704	protein secretion by the type IV secretion system
K9D25_24195	COG3451	type IV secretory pathway VirB4
K9D25_24295	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
K9D25_24320	COG2217	Heavy metal translocating P-type atpase
K9D25_24390	COG1475	DNA binding
K9D25_24435	COG3547	Transposase (IS116 IS110 IS902 family)
K9D25_24495	COG4959	Type IV secretory pathway protease TraF
K9D25_24555	COG3701	Conjugal transfer protein
K9D25_24560	COG3846	protein secretion by the type IV secretion system
K9D25_24570	COG5314	conjugation
K9D25_24575	COG3451	type IV secretory pathway VirB4
K9D25_24585	COG3838	Conjugal transfer protein Trbc
K9D25_24590	COG4962	Type ii secretion system protein e
K9D25_24595	COG3916	Acyl-homoserine-lactone synthase
K9D25_24600	COG1192	Involved in chromosome partitioning
K9D25_24605	COG1475	DNA binding
K9D25_24610	COG0640	Transcriptional regulator
K9D25_24645	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
K9D25_24655	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
K9D25_24685	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
K9D25_24710	COG0587	DNA-directed DNA polymerase activity
K9D25_24855	COG3657	addiction module killer protein