locus-tag	class	description
ACH33_00025	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ACH33_00030	COG3852	Histidine kinase
ACH33_00055	COG1659	Linocin_M18 bacteriocin protein
ACH33_00070	COG1309	transcriptional regulator
ACH33_00075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ACH33_00085	COG0590	tRNA wobble adenosine to inosine editing
ACH33_00090	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
ACH33_00095	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ACH33_00100	COG0596	Alpha beta hydrolase
ACH33_00110	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACH33_00115	COG1024	Enoyl-CoA hydratase
ACH33_00120	COG3290	protein histidine kinase activity
ACH33_00120	COG3829	transcription factor binding
ACH33_00125	COG2112	serine threonine protein kinase
ACH33_00135	COG1842	Phage shock protein A
ACH33_00140	COG0776	regulation of translation
ACH33_00150	COG1587	Uroporphyrinogen-III synthase
ACH33_00150	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ACH33_00180	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
ACH33_00205	COG1122	ATPase activity
ACH33_00220	COG0310	cobalt ion transport
ACH33_00280	COG2315	Protein conserved in bacteria
ACH33_00290	COG1476	TRANSCRIPTIONal
ACH33_00305	COG0579	oxidoreductase
ACH33_00320	COG1028	Short-chain dehydrogenase reductase Sdr
ACH33_00325	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ACH33_00335	COG0516	GMP reductase activity
ACH33_00335	COG0517	IMP dehydrogenase activity
ACH33_00360	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ACH33_00365	COG0187	DNA topoisomerase II activity
ACH33_00375	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ACH33_00380	COG2501	S4 domain
ACH33_00385	COG0592	DNA-directed DNA polymerase activity
ACH33_00390	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ACH33_00395	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ACH33_00405	COG0706	membrane insertase activity
ACH33_00410	COG1847	R3H domain protein
ACH33_00415	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ACH33_00420	COG0445	tRNA wobble uridine modification
ACH33_00425	COG0357	Ribosomal RNA small subunit methyltransferase G
ACH33_00435	COG1475	DNA binding
ACH33_00440	COG1192	Involved in chromosome partitioning
ACH33_00445	COG1475	DNA binding
ACH33_00450	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACH33_00465	COG0668	transmembrane transport
ACH33_00470	COG4481	Protein conserved in bacteria
ACH33_00475	COG0012	GTP binding
ACH33_00480	COG0360	Binds together with S18 to 16S ribosomal RNA
ACH33_00485	COG0629	single-stranded DNA binding
ACH33_00490	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ACH33_00495	COG4241	membrane
ACH33_00500	COG3887	signaling protein consisting of a modified GGDEF domain and a DHH domain
ACH33_00510	COG0305	Participates in initiation and elongation during chromosome replication
ACH33_00515	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ACH33_00520	COG0739	heme binding
ACH33_00525	COG0745	RESPONSE REGULATOR receiver
ACH33_00530	COG5002	protein histidine kinase activity
ACH33_00535	COG4863	YycH protein
ACH33_00540	COG4853	Protein conserved in bacteria
ACH33_00545	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ACH33_00550	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACH33_00560	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ACH33_00565	COG1120	ATPase activity
ACH33_00570	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACH33_00575	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACH33_00580	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
ACH33_00585	COG3973	AAA domain
ACH33_00605	COG0697	spore germination
ACH33_00620	COG0840	transmembrane signaling receptor activity
ACH33_00625	COG2814	Major facilitator Superfamily
ACH33_00630	COG0583	DNA-binding transcription factor activity
ACH33_00635	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACH33_00640	COG0583	DNA-binding transcription factor activity
ACH33_00655	COG2322	membrane
ACH33_00660	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
ACH33_00670	COG1845	cytochrome c oxidase, subunit III
ACH33_00675	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
ACH33_00680	COG0351	phosphomethylpyrimidine kinase
ACH33_00695	COG1801	Protein of unknown function DUF72
ACH33_00700	COG0432	Pfam Uncharacterised protein family UPF0047
ACH33_00705	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACH33_00705	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ACH33_00710	COG1115	amino acid carrier protein
ACH33_00715	COG4187	Peptidase family M20/M25/M40
ACH33_00725	COG0546	phosphoglycolate phosphatase activity
ACH33_00730	COG3842	ATPase activity
ACH33_00735	COG1175	transmembrane transport
ACH33_00740	COG0395	ABC-type sugar transport system, permease component
ACH33_00745	COG1653	transport
ACH33_00750	COG0584	glycerophosphoryl diester phosphodiesterase
ACH33_00755	COG1846	Transcriptional regulator
ACH33_00760	COG1566	PFAM secretion protein HlyD family protein
ACH33_00765	COG2814	Major facilitator Superfamily
ACH33_00780	COG2234	aminopeptidase activity
ACH33_00790	COG2986	histidine ammonia-lyase
ACH33_00800	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ACH33_00805	COG0765	amino acid transport
ACH33_00810	COG0765	amino acid transport
ACH33_00815	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ACH33_00820	COG1115	amino acid carrier protein
ACH33_00915	COG3853	Toxic anion resistance protein (TelA)
ACH33_00920	COG1234	tRNA 3'-trailer cleavage
ACH33_00940	COG0861	Integral membrane protein TerC family
ACH33_00995	COG4841	protein insertion into membrane
ACH33_01005	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACH33_01010	COG1131	(ABC) transporter
ACH33_01030	COG1414	Transcriptional regulator
ACH33_01035	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ACH33_01040	COG1984	allophanate hydrolase subunit 2
ACH33_01045	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ACH33_01070	COG2363	Small membrane protein
ACH33_01080	COG1295	ribonuclease BN
ACH33_01090	COG0697	spore germination
ACH33_01100	COG1131	(ABC) transporter
ACH33_01105	COG4473	ABC transporter
ACH33_01110	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
ACH33_01120	COG0367	asparagine synthase
ACH33_01130	COG4844	belongs to the
ACH33_01140	COG0569	domain protein
ACH33_01140	COG0475	glutathione-regulated potassium exporter activity
ACH33_01145	COG4326	sporulation control protein
ACH33_01150	COG0564	pseudouridine synthase activity
ACH33_01155	COG1078	dGTPase activity
ACH33_01165	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACH33_01175	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ACH33_01180	COG0010	Belongs to the arginase family
ACH33_01190	COG0018	arginyl-trna synthetase
ACH33_01270	COG0247	lactate metabolic process
ACH33_01270	COG2181	nitrate reductase activity
ACH33_01275	COG0183	Belongs to the thiolase family
ACH33_01285	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACH33_01290	COG1960	acyl-CoA dehydrogenase activity
ACH33_01295	COG1960	acyl-CoA dehydrogenase activity
ACH33_01300	COG1703	isobutyryl-CoA mutase activity
ACH33_01310	COG1703	isobutyryl-CoA mutase activity
ACH33_01310	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ACH33_01310	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
ACH33_01315	COG3343	RNA polymerase activity
ACH33_01320	COG0504	CTP synthase activity
ACH33_01325	COG2204	response regulator
ACH33_01330	COG0191	fructose-bisphosphate aldolase activity
ACH33_01335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ACH33_01340	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACH33_01345	COG1494	fructose-1,6-bisphosphatase
ACH33_01350	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ACH33_01360	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ACH33_01370	COG0254	rRNA binding
ACH33_01375	COG1435	thymidine kinase activity
ACH33_01385	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ACH33_01390	COG2890	protein-(glutamine-N5) methyltransferase activity
ACH33_01400	COG0009	L-threonylcarbamoyladenylate synthase
ACH33_01425	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACH33_01430	COG0840	transmembrane signaling receptor activity
ACH33_01435	COG0698	ribose 5-phosphate isomerase
ACH33_01440	COG4475	Protein of unknown function (DUF436)
ACH33_01445	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACH33_01450	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ACH33_01455	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
ACH33_01490	COG0356	it plays a direct role in the translocation of protons across the membrane
ACH33_01505	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ACH33_01510	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ACH33_01515	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ACH33_01520	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ACH33_01525	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ACH33_01530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACH33_01535	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACH33_01545	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACH33_01555	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ACH33_01565	COG0839	Belongs to the complex I subunit 6 family
ACH33_01570	COG0713	ATP synthesis coupled electron transport
ACH33_01575	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ACH33_01580	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ACH33_01585	COG1007	ATP synthesis coupled electron transport
ACH33_01590	COG4836	Membrane
ACH33_01600	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACH33_01605	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACH33_01610	COG2385	sporulation resulting in formation of a cellular spore
ACH33_01615	COG0739	heme binding
ACH33_01620	COG1609	Transcriptional regulator
ACH33_01630	COG4786	Flagellar basal body rod
ACH33_01645	COG1522	sequence-specific DNA binding
ACH33_01650	COG0436	Aminotransferase
ACH33_01655	COG3944	biosynthesis protein
ACH33_01660	COG0489	protein tyrosine kinase activity
ACH33_01665	COG4464	protein tyrosine phosphatase activity
ACH33_01670	COG0673	inositol 2-dehydrogenase activity
ACH33_01695	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
ACH33_01700	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ACH33_01710	COG1136	(ABC) transporter
ACH33_01725	COG3944	biosynthesis protein
ACH33_01765	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACH33_01840	COG0438	transferase activity, transferring glycosyl groups
ACH33_01845	COG0438	transferase activity, transferring glycosyl groups
ACH33_01925	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ACH33_01955	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
ACH33_01960	COG1040	competence protein
ACH33_01975	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
ACH33_01980	COG2747	anti-sigma28 factor FlgM
ACH33_01990	COG4786	Flagellar basal body rod
ACH33_01990	COG1256	bacterial-type flagellum assembly
ACH33_01995	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACH33_02005	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
ACH33_02010	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
ACH33_02040	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
ACH33_02045	COG1516	flagellar protein fliS
ACH33_02070	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
ACH33_02075	COG0765	amino acid transport
ACH33_02080	COG1278	Cold shock
ACH33_02090	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ACH33_02100	COG0653	protein targeting
ACH33_02105	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ACH33_02110	COG3959	Transketolase, thiamine diphosphate binding domain
ACH33_02115	COG3958	Transketolase
ACH33_02125	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ACH33_02130	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ACH33_02140	COG0505	Belongs to the CarA family
ACH33_02145	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACH33_02150	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ACH33_02170	COG0137	argininosuccinate synthase activity
ACH33_02175	COG0165	Argininosuccinate lyase
ACH33_02180	COG2884	Cell division ATP-binding protein ftsE
ACH33_02185	COG2177	Part of the ABC transporter FtsEX involved in
ACH33_02190	COG4942	peptidase
ACH33_02195	COG0793	Belongs to the peptidase S41A family
ACH33_02195	COG3409	Peptidoglycan-binding domain 1 protein
ACH33_02210	COG0556	nucleotide-excision repair
ACH33_02215	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ACH33_02220	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
ACH33_02235	COG0110	maltose O-acetyltransferase activity
ACH33_02260	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ACH33_02265	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ACH33_02270	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
ACH33_02275	COG0131	Imidazoleglycerol-phosphate dehydratase
ACH33_02280	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ACH33_02285	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ACH33_02290	COG0107	imidazoleglycerol-phosphate synthase activity
ACH33_02295	COG0140	phosphoribosyl-ATP diphosphatase activity
ACH33_02295	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ACH33_02310	COG0492	ferredoxin-NADP+ reductase activity
ACH33_02325	COG1660	Displays ATPase and GTPase activities
ACH33_02330	COG0391	Required for morphogenesis under gluconeogenic growth conditions
ACH33_02335	COG1481	regulation of sporulation
ACH33_02340	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACH33_02345	COG0740	serine-type endopeptidase activity
ACH33_02365	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
ACH33_02375	COG2390	Transcriptional regulator
ACH33_02385	COG0126	phosphoglycerate kinase activity
ACH33_02390	COG0149	triose-phosphate isomerase activity
ACH33_02395	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ACH33_02400	COG0148	phosphopyruvate hydratase activity
ACH33_02405	COG0735	belongs to the Fur family
ACH33_02410	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACH33_02420	COG1647	Serine aminopeptidase, S33
ACH33_02425	COG0557	exoribonuclease II activity
ACH33_02430	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ACH33_02465	COG1404	Belongs to the peptidase S8 family
ACH33_02475	COG2755	lipolytic protein G-D-S-L family
ACH33_02490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACH33_02495	COG0745	RESPONSE REGULATOR receiver
ACH33_02500	COG2205	protein histidine kinase activity
ACH33_02500	COG2770	Histidine kinase
ACH33_02505	COG4264	IucA IucC family
ACH33_02510	COG2814	Major facilitator Superfamily
ACH33_02520	COG2423	ornithine cyclodeaminase activity
ACH33_02525	COG0019	diaminopimelate decarboxylase activity
ACH33_02535	COG4264	IucA IucC family
ACH33_02540	COG4264	IucA IucC family
ACH33_02555	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACH33_02560	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACH33_02565	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACH33_02570	COG1910	domain protein
ACH33_02575	COG0725	ABC transporter, periplasmic molybdate-binding protein
ACH33_02580	COG4149	molybdate abc transporter
ACH33_02590	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ACH33_02595	COG0741	lytic transglycosylase activity
ACH33_02595	COG0791	NLP P60 protein
ACH33_02610	COG3011	Protein conserved in bacteria
ACH33_02615	COG0778	Nitroreductase
ACH33_02620	COG1473	amidohydrolase
ACH33_02625	COG2171	N-acyltransferase activity
ACH33_02655	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACH33_02660	COG1414	Transcriptional regulator
ACH33_02680	COG0784	Response regulator, receiver
ACH33_02680	COG3437	response regulator, receiver
ACH33_02685	COG0646	methionine synthase
ACH33_02685	COG1410	methionine synthase
ACH33_02690	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ACH33_02690	COG0646	methionine synthase
ACH33_02710	COG1674	ftsk spoiiie
ACH33_02760	COG0180	Tryptophanyl-tRNA synthetase
ACH33_02770	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
ACH33_02785	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ACH33_02805	COG1999	signal sequence binding
ACH33_02810	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ACH33_02810	COG2508	Transcriptional regulator
ACH33_02815	COG0686	Belongs to the AlaDH PNT family
ACH33_02830	COG2226	methyltransferase
ACH33_02840	COG1119	ATPase activity
ACH33_02845	COG0277	FAD linked oxidase domain protein
ACH33_02865	COG0482	sulfurtransferase activity
ACH33_02875	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ACH33_02885	COG4846	Membrane protein involved in cytochrome C biogenesis
ACH33_02890	COG0833	amino acid
ACH33_02895	COG2186	Transcriptional regulator
ACH33_02900	COG1620	l-lactate permease
ACH33_02910	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ACH33_02920	COG1956	GAF domain-containing protein
ACH33_02925	COG1012	belongs to the aldehyde dehydrogenase family
ACH33_02930	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ACH33_02935	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ACH33_02940	COG0477	Major facilitator Superfamily
ACH33_02945	COG1492	cobalamin metabolic process
ACH33_02955	COG0778	Nitroreductase
ACH33_02960	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
ACH33_02965	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACH33_02970	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
ACH33_02975	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ACH33_02980	COG0406	alpha-ribazole phosphatase activity
ACH33_03010	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
ACH33_03015	COG1739	Uncharacterized protein family UPF0029
ACH33_03020	COG2350	Protein conserved in bacteria
ACH33_03025	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ACH33_03040	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ACH33_03050	COG5577	PFAM Coat F domain
ACH33_03065	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ACH33_03070	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ACH33_03075	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ACH33_03080	COG0697	spore germination
ACH33_03100	COG0477	Major facilitator Superfamily
ACH33_03105	COG1126	abc transporter atp-binding protein
ACH33_03115	COG3706	GGDEF domain
ACH33_03120	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACH33_03125	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACH33_03130	COG1120	ATPase activity
ACH33_03135	COG1393	Belongs to the ArsC family
ACH33_03140	COG0436	Aminotransferase
ACH33_03150	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACH33_03155	COG0509	glycine decarboxylation via glycine cleavage system
ACH33_03175	COG1191	sigma factor activity
ACH33_03190	COG0396	ATPase activity
ACH33_03195	COG0719	Fe-S assembly protein
ACH33_03200	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ACH33_03205	COG0822	iron-sulfur transferase activity
ACH33_03210	COG0719	Fe-S assembly protein
ACH33_03240	COG1846	Transcriptional regulator
ACH33_03245	COG2814	Major facilitator Superfamily
ACH33_03270	COG0730	response to heat
ACH33_03275	COG0737	Belongs to the 5'-nucleotidase family
ACH33_03285	COG3377	Domain of unknown function (DUF1805)
ACH33_03290	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
ACH33_03300	COG2814	Major facilitator Superfamily
ACH33_03305	COG0791	NLP P60 protein
ACH33_03320	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
ACH33_03340	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ACH33_03345	COG3963	phosphatidate phosphatase activity
ACH33_03350	COG1376	ErfK ybiS ycfS ynhG family protein
ACH33_03355	COG0739	heme binding
ACH33_03360	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACH33_03385	COG2445	Protein of unknown function DUF86
ACH33_03395	COG4857	Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate
ACH33_03400	COG0647	UMP catabolic process
ACH33_03405	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ACH33_03410	COG1028	Short-chain dehydrogenase reductase Sdr
ACH33_03415	COG0494	nUDIX hydrolase
ACH33_03420	COG2814	Major facilitator Superfamily
ACH33_03425	COG0583	DNA-binding transcription factor activity
ACH33_03430	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ACH33_03435	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACH33_03440	COG0626	cystathionine gamma-synthase activity
ACH33_03445	COG4837	Protein of unknown function (DUF1462)
ACH33_03460	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ACH33_03465	COG0316	Belongs to the HesB IscA family
ACH33_03495	COG1252	NADH dehydrogenase
ACH33_03520	COG1963	PFAM Acid phosphatase vanadium-dependent haloperoxidase related
ACH33_03525	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACH33_03530	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACH33_03540	COG0028	Belongs to the TPP enzyme family
ACH33_03545	COG0440	acetolactate synthase activity
ACH33_03550	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
ACH33_03555	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACH33_03560	COG0473	3-isopropylmalate dehydrogenase activity
ACH33_03585	COG2155	Conserved Protein
ACH33_03595	COG1363	Peptidase, m42
ACH33_03605	COG0569	domain protein
ACH33_03610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACH33_03620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ACH33_03625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACH33_03625	COG0072	phenylalanine-tRNA ligase activity
ACH33_03630	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
ACH33_03635	COG1286	toxin biosynthetic process
ACH33_03640	COG0583	DNA-binding transcription factor activity
ACH33_03645	COG0531	amino acid
ACH33_03650	COG1193	negative regulation of DNA recombination
ACH33_03655	COG3766	membrane
ACH33_03660	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
ACH33_03670	COG1279	arginine transmembrane transporter activity
ACH33_03675	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACH33_03715	COG0728	peptidoglycan biosynthetic process
ACH33_03720	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACH33_03730	COG1012	belongs to the aldehyde dehydrogenase family
ACH33_03735	COG0506	proline dehydrogenase activity
ACH33_03740	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACH33_03760	COG3278	Belongs to the heme-copper respiratory oxidase family
ACH33_03765	COG1309	transcriptional regulator
ACH33_03770	COG1024	Enoyl-CoA hydratase
ACH33_03775	COG2086	electron transfer activity
ACH33_03780	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ACH33_03785	COG3118	belongs to the thioredoxin family
ACH33_03790	COG0322	excinuclease ABC activity
ACH33_03800	COG1268	BioY protein
ACH33_03805	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACH33_03810	COG2009	succinate dehydrogenase
ACH33_03815	COG1053	succinate dehydrogenase
ACH33_03820	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ACH33_03825	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
ACH33_03840	COG2197	response regulator
ACH33_03845	COG1191	sigma factor activity
ACH33_03850	COG2172	sigma factor antagonist activity
ACH33_03855	COG3284	Transcriptional regulator
ACH33_03860	COG0321	lipoyl(octanoyl) transferase activity
ACH33_03865	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ACH33_03870	COG0022	dehydrogenase e1 component
ACH33_03875	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACH33_03880	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACH33_03885	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ACH33_03890	COG1063	alcohol dehydrogenase
ACH33_03895	COG2197	response regulator
ACH33_03905	COG5401	PFAM Sporulation and spore germination
ACH33_03910	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ACH33_03915	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ACH33_03930	COG0544	peptidyl-prolyl cis-trans isomerase activity
ACH33_03935	COG0740	serine-type endopeptidase activity
ACH33_03940	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ACH33_03945	COG1067	ATP-dependent peptidase activity
ACH33_03945	COG0470	DNA polymerase III
ACH33_03955	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ACH33_03970	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ACH33_03975	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
ACH33_03980	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACH33_03985	COG0181	hydroxymethylbilane synthase activity
ACH33_03995	COG0113	porphobilinogen synthase activity
ACH33_04000	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACH33_04005	COG1388	LysM domain
ACH33_04005	COG1388	LysM domain
ACH33_04050	COG1136	(ABC) transporter
ACH33_04055	COG0525	valine-tRNA ligase activity
ACH33_04060	COG0285	dihydrofolate synthase activity
ACH33_04065	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ACH33_04070	COG0840	transmembrane signaling receptor activity
ACH33_04110	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ACH33_04130	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ACH33_04155	COG0424	maF-like protein
ACH33_04160	COG2003	Belongs to the UPF0758 family
ACH33_04165	COG1077	Cell shape determining protein MreB Mrl
ACH33_04170	COG1792	Involved in formation and maintenance of cell shape
ACH33_04180	COG0850	regulation of cytokinetic process
ACH33_04185	COG2894	cell division
ACH33_04190	COG0772	Belongs to the SEDS family
ACH33_04200	COG1994	Peptidase M50
ACH33_04205	COG1530	ribonuclease E activity
ACH33_04210	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ACH33_04215	COG2868	ribosomal protein
ACH33_04220	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ACH33_04225	COG0028	Belongs to the TPP enzyme family
ACH33_04230	COG3290	protein histidine kinase activity
ACH33_04235	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ACH33_04240	COG4492	Belongs to the UPF0735 family
ACH33_04245	COG0460	homoserine dehydrogenase
ACH33_04250	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
ACH33_04255	COG0083	homoserine kinase activity
ACH33_04260	COG0077	Prephenate dehydratase
ACH33_04265	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACH33_04270	COG0217	transcriptional regulatory protein
ACH33_04290	COG0632	four-way junction helicase activity
ACH33_04295	COG2255	four-way junction helicase activity
ACH33_04305	COG2364	Membrane
ACH33_04310	COG1846	Transcriptional regulator
ACH33_04320	COG2247	cell wall binding repeat
ACH33_04320	COG2385	sporulation resulting in formation of a cellular spore
ACH33_04325	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ACH33_04330	COG0343	queuine tRNA-ribosyltransferase activity
ACH33_04335	COG1862	Preprotein translocase
ACH33_04345	COG0598	Magnesium transport protein CorA
ACH33_04350	COG2244	polysaccharide biosynthetic process
ACH33_04380	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
ACH33_04380	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ACH33_04385	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACH33_04390	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ACH33_04400	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACH33_04410	COG0124	histidyl-tRNA synthetase
ACH33_04415	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ACH33_04425	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
ACH33_04435	COG1959	2 iron, 2 sulfur cluster binding
ACH33_04440	COG1104	cysteine desulfurase activity
ACH33_04475	COG0628	permease
ACH33_04480	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ACH33_04485	COG4472	Bacterial protein of unknown function (DUF965)
ACH33_04495	COG3906	Belongs to the UPF0473 family
ACH33_04515	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ACH33_04535	COG0572	uridine kinase
ACH33_04540	COG0768	penicillin binding
ACH33_04550	COG0789	Transcriptional regulator
ACH33_04595	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACH33_04600	COG1131	(ABC) transporter
ACH33_04620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACH33_04635	COG0028	Belongs to the TPP enzyme family
ACH33_04655	COG0318	PFAM AMP-dependent synthetase and ligase
ACH33_04665	COG1012	belongs to the aldehyde dehydrogenase family
ACH33_04670	COG0473	3-isopropylmalate dehydrogenase activity
ACH33_04680	COG4638	Rieske (2fe-2S)
ACH33_04690	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACH33_04705	COG3876	Protein conserved in bacteria
ACH33_04710	COG3853	Toxic anion resistance protein (TelA)
ACH33_04715	COG0338	D12 class N6 adenine-specific DNA methyltransferase
ACH33_04720	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ACH33_04725	COG2224	Isocitrate lyase
ACH33_04730	COG1380	Effector of murein hydrolase LrgA
ACH33_04735	COG1346	cytolysis
ACH33_04745	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACH33_04750	COG4605	iron ion homeostasis
ACH33_04755	COG4604	ABC transporter, ATP-binding protein
ACH33_04760	COG4607	ABC-type enterochelin transport system periplasmic component
ACH33_04765	COG2217	Heavy metal translocating P-type atpase
ACH33_04770	COG0640	Transcriptional regulator
ACH33_04775	COG0675	Transposase, IS605 OrfB family
ACH33_04785	COG3852	Histidine kinase
ACH33_04790	COG2204	response regulator
ACH33_04795	COG0010	Belongs to the arginase family
ACH33_04800	COG0786	glutamate:sodium symporter activity
ACH33_04830	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACH33_04835	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACH33_04940	COG3584	3D domain protein
ACH33_04940	COG1388	LysM domain
ACH33_04950	COG1271	oxidase subunit
ACH33_04955	COG1294	oxidase, subunit
ACH33_04975	COG1027	Aspartate ammonia-lyase
ACH33_04995	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ACH33_05005	COG2045	Belongs to the ComB family
ACH33_05025	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ACH33_05035	COG0778	Nitroreductase
ACH33_05040	COG4187	Peptidase family M20/M25/M40
ACH33_05050	COG0765	amino acid transport
ACH33_05055	COG1126	abc transporter atp-binding protein
ACH33_05065	COG3949	Membrane
ACH33_05070	COG0681	Belongs to the peptidase S26 family
ACH33_05075	COG1597	lipid kinase activity
ACH33_05080	COG0398	Pfam SNARE associated Golgi protein
ACH33_05085	COG2267	carboxylic ester hydrolase activity
ACH33_05100	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACH33_05120	COG1966	Carbon starvation protein
ACH33_05135	COG3279	Response regulator of the LytR AlgR family
ACH33_05140	COG3275	phosphorelay sensor kinase activity
ACH33_05145	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ACH33_05155	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
ACH33_05160	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
ACH33_05165	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ACH33_05170	COG1534	Rna-binding protein
ACH33_05175	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ACH33_05180	COG1713	HD superfamily hydrolase involved in NAD metabolism
ACH33_05185	COG0799	negative regulation of ribosome biogenesis
ACH33_05190	COG2226	methyltransferase
ACH33_05200	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ACH33_05210	COG1596	polysaccharide export
ACH33_05210	COG1555	photosystem II stabilization
ACH33_05235	COG2333	competence protein COMEC
ACH33_05235	COG0658	competence protein
ACH33_05240	COG1595	DNA-templated transcription, initiation
ACH33_05250	COG1466	dna polymerase III delta subunit
ACH33_05255	COG0268	Binds directly to 16S ribosomal RNA
ACH33_05270	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACH33_05285	COG0481	GTPase activity
ACH33_05290	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACH33_05295	COG1420	regulation of RNA biosynthetic process
ACH33_05300	COG0459	protein refolding
ACH33_05325	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ACH33_05330	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACH33_05335	COG3290	protein histidine kinase activity
ACH33_05340	COG4565	transcriptional regulatory protein
ACH33_05345	COG1301	dicarboxylic acid transport
ACH33_05350	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ACH33_05360	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
ACH33_05365	COG1283	sodium-dependent phosphate transmembrane transporter activity
ACH33_05380	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACH33_05380	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ACH33_05400	COG1595	DNA-templated transcription, initiation
ACH33_05420	COG2814	Major facilitator Superfamily
ACH33_05430	COG1028	Short-chain dehydrogenase reductase Sdr
ACH33_05435	COG2733	membrane
ACH33_05440	COG4191	Histidine kinase
ACH33_05445	COG0784	Response regulator, receiver
ACH33_05450	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACH33_05455	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACH33_05460	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ACH33_05465	COG1610	YqeY-like protein
ACH33_05480	COG1702	phosphate starvation-inducible protein PhoH
ACH33_05485	COG1480	7TM receptor with intracellular HD hydrolase
ACH33_05490	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ACH33_05500	COG0295	cytidine deaminase activity
ACH33_05505	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ACH33_05510	COG1381	Involved in DNA repair and RecF pathway recombination
ACH33_05515	COG0752	glycyl-tRNA synthetase alpha subunit
ACH33_05520	COG0751	glycine-tRNA ligase activity
ACH33_05525	COG0517	IMP dehydrogenase activity
ACH33_05530	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
ACH33_05540	COG0358	DNA primase activity
ACH33_05545	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ACH33_05555	COG1960	acyl-CoA dehydrogenase activity
ACH33_05560	COG0318	PFAM AMP-dependent synthetase and ligase
ACH33_05575	COG2384	SAM-dependent methyltransferase
ACH33_05580	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ACH33_05600	COG2843	Capsule synthesis protein
ACH33_05610	COG0312	modulator of DNA gyrase
ACH33_05615	COG0312	modulator of DNA gyrase
ACH33_05620	COG2827	Endonuclease containing a URI domain
ACH33_05665	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACH33_05670	COG0726	polysaccharide deacetylase
ACH33_05680	COG0471	metal ion transport
ACH33_05705	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ACH33_05710	COG2814	Major facilitator Superfamily
ACH33_05725	COG1424	Catalyzes the transformation of pimelate into pimeloyl- CoA with concomitant hydrolysis of ATP to AMP
ACH33_05735	COG2031	fatty acid transporter
ACH33_05740	COG4977	sequence-specific DNA binding
ACH33_05745	COG0010	Belongs to the arginase family
ACH33_05755	COG1228	amidohydrolase
ACH33_05765	COG1802	Transcriptional regulator
ACH33_05775	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACH33_05780	COG2814	Major facilitator Superfamily
ACH33_05800	COG1876	peptidase activity
ACH33_05805	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ACH33_05815	COG0531	amino acid
ACH33_05835	COG4838	Belongs to the UPF0358 family
ACH33_05840	COG4637	Psort location Cytoplasmic, score
ACH33_05845	COG0783	Belongs to the Dps family
ACH33_05850	COG2217	Heavy metal translocating P-type atpase
ACH33_05855	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
ACH33_05870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACH33_05875	COG0584	glycerophosphoryl diester phosphodiesterase
ACH33_05885	COG1733	regulation of RNA biosynthetic process
ACH33_05900	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ACH33_05915	COG1114	Component of the transport system for branched-chain amino acids
ACH33_05930	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACH33_05935	COG0351	phosphomethylpyrimidine kinase
ACH33_05960	COG1607	acyl-coa hydrolase
ACH33_05965	COG0390	transport system, permease component
ACH33_05970	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACH33_05975	COG0457	Tetratricopeptide repeat
ACH33_05975	COG0705	Rhomboid family
ACH33_05995	COG1363	Peptidase, m42
ACH33_06005	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ACH33_06010	COG0387	Pfam Sodium calcium exchanger
ACH33_06015	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ACH33_06040	COG3119	arylsulfatase activity
ACH33_06045	COG0463	Glycosyl transferase, family 2
ACH33_06050	COG3773	Cell wall hydrolase
ACH33_06050	COG3409	Peptidoglycan-binding domain 1 protein
ACH33_06055	COG0640	Transcriptional regulator
ACH33_06085	COG3679	Belongs to the UPF0342 family
ACH33_06090	COG4471	UPF0298 protein
ACH33_06095	COG0589	response to stress
ACH33_06115	COG1459	type II secretion system
ACH33_06120	COG2165	general secretion pathway protein
ACH33_06145	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ACH33_06160	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ACH33_06165	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ACH33_06185	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ACH33_06190	COG0509	glycine decarboxylation via glycine cleavage system
ACH33_06195	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACH33_06200	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ACH33_06205	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ACH33_06215	COG0095	Lipoate-protein ligase
ACH33_06225	COG2205	protein histidine kinase activity
ACH33_06230	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ACH33_06235	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ACH33_06245	COG5609	conserved protein (DUF2294)
ACH33_06250	COG3829	transcription factor binding
ACH33_06250	COG3290	protein histidine kinase activity
ACH33_06275	COG1666	GTP binding
ACH33_06285	COG1321	iron dependent repressor
ACH33_06290	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACH33_06300	COG3872	metal-dependent enzyme
ACH33_06305	COG2010	Cytochrome c
ACH33_06315	COG0006	proline dipeptidase activity
ACH33_06320	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ACH33_06325	COG2814	Major facilitator Superfamily
ACH33_06335	COG3854	ATPases associated with a variety of cellular activities
ACH33_06375	COG0511	ligase activity, forming carbon-carbon bonds
ACH33_06380	COG0439	Biotin carboxylase
ACH33_06385	COG1302	Protein conserved in bacteria
ACH33_06400	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACH33_06405	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ACH33_06410	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ACH33_06415	COG1570	exodeoxyribonuclease VII activity
ACH33_06420	COG1722	exodeoxyribonuclease VII activity
ACH33_06430	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ACH33_06435	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
ACH33_06440	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ACH33_06445	COG1438	arginine binding
ACH33_06450	COG0497	DNA recombination
ACH33_06455	COG0750	zinc metalloprotease
ACH33_06460	COG0745	RESPONSE REGULATOR receiver
ACH33_06470	COG0613	PHP domain protein
ACH33_06475	COG2153	protein acetylation
ACH33_06480	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
ACH33_06530	COG1982	Orn Lys Arg decarboxylase major
ACH33_06540	COG4493	Belongs to the UPF0637 family
ACH33_06550	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ACH33_06560	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ACH33_06575	COG3829	transcription factor binding
ACH33_06575	COG3290	protein histidine kinase activity
ACH33_06595	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
ACH33_06600	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACH33_06625	COG1393	Belongs to the ArsC family
ACH33_06630	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACH33_06635	COG1024	Enoyl-CoA hydratase
ACH33_06645	COG0439	Biotin carboxylase
ACH33_06650	COG0511	ligase activity, forming carbon-carbon bonds
ACH33_06660	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACH33_06665	COG1309	transcriptional regulator
ACH33_06670	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
ACH33_06675	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ACH33_06685	COG0275	rRNA processing
ACH33_06700	COG0768	penicillin binding
ACH33_06710	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ACH33_06715	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ACH33_06720	COG0772	Belongs to the SEDS family
ACH33_06725	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ACH33_06730	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ACH33_06735	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ACH33_06740	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ACH33_06755	COG3856	small basic protein
ACH33_06760	COG0849	cell division
ACH33_06765	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ACH33_06775	COG1191	sigma factor activity
ACH33_06780	COG1191	sigma factor activity
ACH33_06790	COG1873	PFAM PRC-barrel domain
ACH33_06800	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ACH33_06805	COG1799	cell septum assembly
ACH33_06810	COG0762	integral membrane protein
ACH33_06815	COG2302	S4 RNA-binding domain
ACH33_06820	COG3599	regulation of cell shape
ACH33_06825	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ACH33_06830	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ACH33_06835	COG0564	pseudouridine synthase activity
ACH33_06840	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
ACH33_06850	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ACH33_06860	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ACH33_06865	COG0543	2 iron, 2 sulfur cluster binding
ACH33_06870	COG0167	dihydroorotate dehydrogenase activity
ACH33_06875	COG0284	orotidine-5'-phosphate decarboxylase activity
ACH33_06880	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ACH33_06885	COG2244	polysaccharide biosynthetic process
ACH33_06895	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ACH33_06905	COG1561	YicC-like family, N-terminal region
ACH33_06910	COG2052	Domain of unknown function (DUF370)
ACH33_06915	COG0194	GDP metabolic process
ACH33_06920	COG1758	RNA polymerase activity
ACH33_06925	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACH33_06930	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ACH33_06935	COG0242	peptide deformylase activity
ACH33_06940	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ACH33_06945	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACH33_06945	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ACH33_06950	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ACH33_06955	COG0631	protein serine/threonine phosphatase activity
ACH33_06960	COG0515	serine threonine protein kinase
ACH33_06960	COG2815	serine threonine protein kinase
ACH33_06965	COG1162	GTPase activity
ACH33_06970	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ACH33_06975	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ACH33_06980	COG1760	l-serine dehydratase
ACH33_06985	COG1760	l-serine dehydratase
ACH33_06990	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
ACH33_06995	COG1285	pathogenesis
ACH33_07000	COG0742	ribosomal rna small subunit methyltransferase
ACH33_07005	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ACH33_07010	COG3314	Sporulation integral membrane protein YlbJ
ACH33_07015	COG1752	Esterase of the alpha-beta hydrolase superfamily
ACH33_07020	COG3480	Lon protease (S16) C-terminal proteolytic domain
ACH33_07025	COG1323	Belongs to the UPF0348 family
ACH33_07035	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ACH33_07055	COG0416	fatty acid biosynthetic process
ACH33_07065	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ACH33_07070	COG1028	Short-chain dehydrogenase reductase Sdr
ACH33_07075	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ACH33_07080	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ACH33_07085	COG0571	ribonuclease III activity
ACH33_07090	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ACH33_07095	COG1196	nuclear chromosome segregation
ACH33_07100	COG0552	protein localization to endoplasmic reticulum
ACH33_07110	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ACH33_07115	COG0228	four-way junction DNA binding
ACH33_07120	COG1837	Belongs to the UPF0109 family
ACH33_07130	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ACH33_07135	COG0336	Belongs to the RNA methyltransferase TrmD family
ACH33_07140	COG0335	large ribosomal subunit rRNA binding
ACH33_07145	COG0681	Belongs to the peptidase S26 family
ACH33_07155	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ACH33_07165	COG2257	FlhB HrpN YscU SpaS Family
ACH33_07170	COG0792	nuclease activity
ACH33_07185	COG0045	succinate-CoA ligase (ADP-forming) activity
ACH33_07190	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
ACH33_07195	COG0758	DNA mediated transformation
ACH33_07195	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACH33_07200	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACH33_07205	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ACH33_07210	COG4974	Belongs to the 'phage' integrase family
ACH33_07215	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ACH33_07220	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ACH33_07225	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ACH33_07230	COG1815	bacterial-type flagellum-dependent cell motility
ACH33_07235	COG1558	bacterial-type flagellum-dependent cell motility
ACH33_07240	COG1677	Flagellar hook-basal body complex protein FliE
ACH33_07245	COG1766	The M ring may be actively involved in energy transduction
ACH33_07250	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACH33_07260	COG1157	protein secretion by the type III secretion system
ACH33_07265	COG2882	bacterial-type flagellum organization
ACH33_07275	COG3144	bacterial-type flagellum assembly
ACH33_07280	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ACH33_07290	COG4786	Flagellar basal body rod
ACH33_07295	COG1582	Flagellar protein (FlbD)
ACH33_07305	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACH33_07310	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ACH33_07310	COG1776	CheC inhibitor of MCP methylation
ACH33_07315	COG2201	protein-glutamate methylesterase activity
ACH33_07320	COG3190	flagellar
ACH33_07325	COG1338	Plays a role in the flagellum-specific transport system
ACH33_07330	COG1987	bacterial-type flagellum assembly
ACH33_07335	COG1684	flagellar biosynthetic protein fliR
ACH33_07340	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACH33_07345	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ACH33_07350	COG1419	protein localization to endoplasmic reticulum
ACH33_07355	COG0455	bacterial-type flagellum organization
ACH33_07360	COG2201	protein-glutamate methylesterase activity
ACH33_07365	COG0643	Histidine kinase
ACH33_07365	COG2198	Histidine kinase
ACH33_07370	COG0835	chemotaxis
ACH33_07375	COG1776	CheC inhibitor of MCP methylation
ACH33_07380	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ACH33_07390	COG1191	sigma factor activity
ACH33_07410	COG0052	Belongs to the universal ribosomal protein uS2 family
ACH33_07415	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ACH33_07420	COG0528	UMP kinase activity
ACH33_07425	COG0233	cytoplasmic translational termination
ACH33_07430	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
ACH33_07435	COG4589	Belongs to the CDS family
ACH33_07440	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ACH33_07445	COG0750	zinc metalloprotease
ACH33_07450	COG0442	prolyl-tRNA aminoacylation
ACH33_07455	COG2176	DNA-directed DNA polymerase activity
ACH33_07460	COG0779	Required for maturation of 30S ribosomal subunits
ACH33_07465	COG0195	Participates in both transcription termination and antitermination
ACH33_07470	COG2740	Nucleic-acid-binding protein implicated in transcription termination
ACH33_07475	COG1358	cellular component organization or biogenesis
ACH33_07480	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ACH33_07485	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ACH33_07490	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
ACH33_07495	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ACH33_07500	COG0196	riboflavin kinase activity
ACH33_07505	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ACH33_07510	COG1185	polyribonucleotide nucleotidyltransferase activity
ACH33_07515	COG0726	polysaccharide deacetylase
ACH33_07520	COG0612	Peptidase, M16
ACH33_07525	COG0756	dUTP diphosphatase activity
ACH33_07535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACH33_07540	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ACH33_07545	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ACH33_07550	COG0527	aspartate kinase activity
ACH33_07555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACH33_07560	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ACH33_07565	COG0582	viral genome integration into host DNA
ACH33_07715	COG1484	DNA-dependent DNA replication
ACH33_07740	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
ACH33_07810	COG2868	ribosomal protein
ACH33_07925	COG4824	toxin secretion phage lysis holin
ACH33_07930	COG1876	peptidase activity
ACH33_07945	COG2801	Transposase and inactivated derivatives
ACH33_07980	COG2801	Transposase and inactivated derivatives
ACH33_07985	COG1633	Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME)
ACH33_08015	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
ACH33_08035	COG4191	Histidine kinase
ACH33_08050	COG1215	transferase activity, transferring glycosyl groups
ACH33_08065	COG2076	Multidrug Resistance protein
ACH33_08070	COG2076	Multidrug Resistance protein
ACH33_08080	COG0697	spore germination
ACH33_08090	COG1114	Component of the transport system for branched-chain amino acids
ACH33_08095	COG1024	Enoyl-CoA hydratase
ACH33_08100	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ACH33_08110	COG1024	Enoyl-CoA hydratase
ACH33_08115	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACH33_08120	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACH33_08125	COG0183	Belongs to the thiolase family
ACH33_08130	COG0183	Belongs to the thiolase family
ACH33_08140	COG3396	Phenylacetate-CoA oxygenase
ACH33_08155	COG2151	metal-sulfur cluster biosynthetic enzyme
ACH33_08160	COG1012	belongs to the aldehyde dehydrogenase family
ACH33_08170	COG0431	NADPH-dependent FMN reductase
ACH33_08195	COG2521	methyltransferase
ACH33_08195	COG2136	Putative SAM-dependent methyltransferase
ACH33_08200	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
ACH33_08205	COG1923	regulation of RNA biosynthetic process
ACH33_08215	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
ACH33_08220	COG2011	ABC-type metal ion transport system permease component
ACH33_08250	COG2340	Cysteine-rich secretory protein family
ACH33_08255	COG0464	growth
ACH33_08265	COG2814	Major facilitator Superfamily
ACH33_08270	COG1566	PFAM secretion protein HlyD family protein
ACH33_08275	COG1309	transcriptional regulator
ACH33_08285	COG2258	MOSC domain
ACH33_08295	COG0842	Transport permease protein
ACH33_08295	COG1716	ATPase activity
ACH33_08295	COG1131	(ABC) transporter
ACH33_08325	COG3335	DDE superfamily endonuclease
ACH33_08335	COG0716	FMN binding
ACH33_08345	COG3290	protein histidine kinase activity
ACH33_08395	COG3693	PFAM glycoside hydrolase, family 10
ACH33_08400	COG2076	Multidrug Resistance protein
ACH33_08405	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
ACH33_08410	COG4948	Mandelate Racemase Muconate Lactonizing
ACH33_08445	COG0840	transmembrane signaling receptor activity
ACH33_08460	COG3835	regulator
ACH33_08465	COG1012	belongs to the aldehyde dehydrogenase family
ACH33_08470	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ACH33_08480	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACH33_08495	COG1309	transcriptional regulator
ACH33_08565	COG5377	YqaJ viral recombinase family
ACH33_08620	COG2315	Protein conserved in bacteria
ACH33_08635	COG3728	DNA packaging
ACH33_08635	COG5484	DNA packaging
ACH33_08640	COG1783	phage Terminase large subunit
ACH33_08740	COG3299	homolog of phage Mu protein gp47
ACH33_08765	COG4824	toxin secretion phage lysis holin
ACH33_08770	COG1876	peptidase activity
ACH33_08780	COG5002	protein histidine kinase activity
ACH33_08790	COG1984	allophanate hydrolase subunit 2
ACH33_08800	COG0439	Biotin carboxylase
ACH33_08805	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ACH33_08810	COG3290	protein histidine kinase activity
ACH33_08810	COG3829	transcription factor binding
ACH33_08820	COG1984	allophanate hydrolase subunit 2
ACH33_08830	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ACH33_08835	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
ACH33_08845	COG0438	transferase activity, transferring glycosyl groups
ACH33_08850	COG0438	transferase activity, transferring glycosyl groups
ACH33_08855	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ACH33_08875	COG1294	oxidase, subunit
ACH33_08880	COG1271	oxidase subunit
ACH33_08890	COG1309	transcriptional regulator
ACH33_08905	COG1378	Sugar-specific transcriptional regulator TrmB
ACH33_08920	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACH33_08920	COG2207	Transcriptional regulator
ACH33_08925	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACH33_08930	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACH33_08935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACH33_08940	COG2819	hydrolase of the alpha beta superfamily
ACH33_08945	COG0778	Nitroreductase
ACH33_08955	COG1840	ABC-type Fe3 transport system, periplasmic component
ACH33_08960	COG3842	ATPase activity
ACH33_08970	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ACH33_08985	COG1349	DNA-binding transcription factor activity
ACH33_08990	COG0534	Mate efflux family protein
ACH33_09000	COG2814	Major facilitator Superfamily
ACH33_09010	COG1809	phosphosulfolactate synthase activity
ACH33_09015	COG2814	Major facilitator Superfamily
ACH33_09020	COG2707	UPF0756 membrane protein
ACH33_09025	COG2045	Belongs to the ComB family
ACH33_09040	COG0247	lactate metabolic process
ACH33_09045	COG1139	Iron-sulfur cluster binding protein
ACH33_09050	COG1556	Lactate utilization protein
ACH33_09055	COG0697	spore germination
ACH33_09060	COG0531	amino acid
ACH33_09075	COG1764	response to oxidative stress
ACH33_09085	COG0833	amino acid
ACH33_09105	COG0835	chemotaxis
ACH33_09105	COG0784	Response regulator, receiver
ACH33_09120	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ACH33_09125	COG4100	CystaTHIonine beta-lyase family protein involved in aluminum resistance
ACH33_09130	COG0789	Transcriptional regulator
ACH33_09135	COG0174	glutamine synthetase
ACH33_09145	COG0745	RESPONSE REGULATOR receiver
ACH33_09180	COG1132	(ABC) transporter
ACH33_09190	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
ACH33_09195	COG1122	ATPase activity
ACH33_09200	COG4721	ABC-type cobalt transport system, permease component
ACH33_09205	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ACH33_09210	COG0730	response to heat
ACH33_09215	COG3850	Histidine kinase
ACH33_09220	COG2197	response regulator
ACH33_09240	COG1131	(ABC) transporter
ACH33_09275	COG1331	Highly conserved protein containing a thioredoxin domain
ACH33_09280	COG1331	Highly conserved protein containing a thioredoxin domain
ACH33_09300	COG0671	phosphoesterase, PA-phosphatase related
ACH33_09305	COG0586	Pfam SNARE associated Golgi protein
ACH33_09310	COG0438	transferase activity, transferring glycosyl groups
ACH33_09315	COG1215	transferase activity, transferring glycosyl groups
ACH33_09325	COG1331	Highly conserved protein containing a thioredoxin domain
ACH33_09330	COG0393	Putative heavy-metal-binding
ACH33_09335	COG4086	secreted protein
ACH33_09340	COG0460	homoserine dehydrogenase
ACH33_09350	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ACH33_09355	COG0427	acetyl-CoA hydrolase
ACH33_09370	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ACH33_09395	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACH33_09400	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACH33_09405	COG1376	ErfK ybiS ycfS ynhG family protein
ACH33_09410	COG0183	Belongs to the thiolase family
ACH33_09425	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACH33_09430	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACH33_09440	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACH33_09445	COG0746	molybdenum cofactor guanylyltransferase activity
ACH33_09450	COG0303	'Molybdopterin
ACH33_09455	COG1763	Mo-molybdopterin cofactor biosynthetic process
ACH33_09460	COG0314	molybdopterin synthase activity
ACH33_09490	COG0488	(ABC) transporter
ACH33_09495	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ACH33_09510	COG0583	DNA-binding transcription factor activity
ACH33_09515	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
ACH33_09525	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
ACH33_09530	COG0243	molybdopterin cofactor binding
ACH33_09535	COG0561	phosphatase activity
ACH33_09555	COG0189	ligase activity
ACH33_09565	COG3949	Membrane
ACH33_09570	COG4709	membrane
ACH33_09575	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ACH33_09585	COG0741	lytic transglycosylase activity
ACH33_09600	COG1611	Belongs to the LOG family
ACH33_09605	COG5018	Exonuclease
ACH33_09615	COG1346	cytolysis
ACH33_09620	COG1380	Effector of murein hydrolase LrgA
ACH33_09625	COG0583	DNA-binding transcription factor activity
ACH33_09645	COG1404	Belongs to the peptidase S8 family
ACH33_09655	COG1012	belongs to the aldehyde dehydrogenase family
ACH33_09665	COG1401	restriction endodeoxyribonuclease activity
ACH33_09665	COG1401	restriction endodeoxyribonuclease activity
ACH33_09675	COG0640	Transcriptional regulator
ACH33_09680	COG0798	PFAM Bile acid sodium symporter
ACH33_09685	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ACH33_09690	COG1252	NADH dehydrogenase
ACH33_09695	COG1388	LysM domain
ACH33_09695	COG0791	NLP P60 protein
ACH33_09700	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACH33_09705	COG4224	UPF0291 protein
ACH33_09720	COG0840	transmembrane signaling receptor activity
ACH33_09735	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ACH33_09775	COG2211	Major facilitator Superfamily
ACH33_09785	COG0277	FAD linked oxidase domain protein
ACH33_09790	COG0247	lactate metabolic process
ACH33_09795	COG0277	FAD linked oxidase domain protein
ACH33_09800	COG2234	aminopeptidase activity
ACH33_09820	COG0084	hydrolase, TatD family'
ACH33_09825	COG1547	Domain of unknown function (DUF309)
ACH33_09830	COG3540	Alkaline phosphatase
ACH33_09840	COG1388	LysM domain
ACH33_09840	COG3584	3D domain protein
ACH33_09845	COG1074	ATP-dependent DNA helicase activity
ACH33_09850	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
ACH33_09855	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACH33_09860	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ACH33_09865	COG1028	Short-chain dehydrogenase reductase Sdr
ACH33_09875	COG0534	Mate efflux family protein
ACH33_09880	COG0840	transmembrane signaling receptor activity
ACH33_09890	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACH33_09900	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
ACH33_09905	COG1607	acyl-coa hydrolase
ACH33_09910	COG0551	DNA topoisomerase type I activity
ACH33_09910	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ACH33_09915	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
ACH33_09920	COG1113	amino acid transport
ACH33_09925	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ACH33_09930	COG0686	Belongs to the AlaDH PNT family
ACH33_09935	COG4869	propanediol catabolic process
ACH33_09950	COG2186	Transcriptional regulator
ACH33_09965	COG1028	Short-chain dehydrogenase reductase Sdr
ACH33_09970	COG0644	oxidoreductase
ACH33_09980	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ACH33_09990	COG1309	transcriptional regulator
ACH33_09995	COG3844	kynureninase activity
ACH33_10010	COG0733	neurotransmitter:sodium symporter activity
ACH33_10030	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
ACH33_10050	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACH33_10065	COG2801	Transposase and inactivated derivatives
ACH33_10085	COG0582	viral genome integration into host DNA
ACH33_10095	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ACH33_10100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ACH33_10105	COG0697	spore germination
ACH33_10110	COG0583	DNA-binding transcription factor activity
ACH33_10120	COG2807	transmembrane transport
ACH33_10125	COG2186	Transcriptional regulator
ACH33_10130	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACH33_10155	COG2608	mercury ion transmembrane transporter activity
ACH33_10165	COG2217	Heavy metal translocating P-type atpase
ACH33_10185	COG1401	restriction endodeoxyribonuclease activity
ACH33_10190	COG0419	ATPase involved in DNA repair
ACH33_10265	COG1363	Peptidase, m42
ACH33_10290	COG0180	Tryptophanyl-tRNA synthetase
ACH33_10295	COG0180	Tryptophanyl-tRNA synthetase
ACH33_10330	COG0527	aspartate kinase activity
ACH33_10340	COG3192	ethanolamine utilization protein
ACH33_10345	COG4302	ethanolamine ammonia-lyase activity
ACH33_10350	COG4303	Ethanolamine ammonia lyase large subunit
ACH33_10355	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ACH33_10360	COG4576	ethanolamine utilization protein EutN carboxysome structural protein Ccml
ACH33_10370	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
ACH33_10375	COG1012	belongs to the aldehyde dehydrogenase family
ACH33_10375	COG1454	alcohol dehydrogenase
ACH33_10380	COG4816	utilization protein
ACH33_10385	COG4302	ethanolamine ammonia-lyase activity
ACH33_10390	COG4303	Ethanolamine ammonia lyase large subunit
ACH33_10395	COG4819	ethanolamine utilization protein
ACH33_10410	COG4917	ethanolamine utilization protein
ACH33_10415	COG4810	utilization protein
ACH33_10430	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ACH33_10435	COG4843	Uncharacterized protein conserved in bacteria (DUF2179)
ACH33_10440	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ACH33_10450	COG2056	Na+-H+ antiporter family
ACH33_10455	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACH33_10460	COG1164	Oligoendopeptidase f
ACH33_10465	COG0656	L-ascorbic acid biosynthetic process
ACH33_10470	COG0577	efflux transmembrane transporter activity
ACH33_10475	COG1136	(ABC) transporter
ACH33_10480	COG5002	protein histidine kinase activity
ACH33_10485	COG0745	RESPONSE REGULATOR receiver
ACH33_10490	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ACH33_10500	COG0833	amino acid
ACH33_10510	COG2084	Dehydrogenase
ACH33_10515	COG3773	Cell wall hydrolase
ACH33_10535	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
ACH33_10540	COG1199	ATP-dependent helicase activity
ACH33_10555	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ACH33_10560	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ACH33_10560	COG0662	Cupin 2, conserved barrel domain protein
ACH33_10570	COG0463	Glycosyl transferase, family 2
ACH33_10570	COG0457	Tetratricopeptide repeat
ACH33_10575	COG0457	Tetratricopeptide repeat
ACH33_10575	COG0463	Glycosyl transferase, family 2
ACH33_10625	COG2002	toxin-antitoxin pair type II binding
ACH33_10640	COG2843	Capsule synthesis protein
ACH33_10645	COG0583	DNA-binding transcription factor activity
ACH33_10650	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ACH33_10655	COG0066	3-isopropylmalate dehydratase activity
ACH33_10665	COG1164	Oligoendopeptidase f
ACH33_10675	COG1098	S1 RNA binding domain
ACH33_10685	COG0187	DNA topoisomerase II activity
ACH33_10690	COG0352	thiamine-phosphate diphosphorylase activity
ACH33_10695	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
ACH33_10705	COG0506	proline dehydrogenase activity
ACH33_10715	COG1454	alcohol dehydrogenase
ACH33_10730	COG3852	Histidine kinase
ACH33_10735	COG2204	response regulator
ACH33_10760	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ACH33_10765	COG1482	cell wall glycoprotein biosynthetic process
ACH33_10770	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACH33_10780	COG1506	peptidase
ACH33_10785	COG1388	LysM domain
ACH33_10785	COG3858	chitin binding
ACH33_10790	COG2962	Rard protein
ACH33_10810	COG2885	chlorophyll binding
ACH33_10835	COG1396	sequence-specific DNA binding
ACH33_10850	COG3858	chitin binding
ACH33_10850	COG1388	LysM domain
ACH33_10860	COG0671	phosphoesterase, PA-phosphatase related
ACH33_10865	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ACH33_10870	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACH33_10870	COG2247	cell wall binding repeat
ACH33_10875	COG1164	Oligoendopeptidase f
ACH33_10880	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ACH33_10890	COG0318	PFAM AMP-dependent synthetase and ligase
ACH33_10895	COG1960	acyl-CoA dehydrogenase activity
ACH33_10900	COG0183	Belongs to the thiolase family
ACH33_10905	COG1024	Enoyl-CoA hydratase
ACH33_10905	COG1250	3-hydroxyacyl-CoA dehydrogenase
ACH33_10920	COG0653	protein targeting
ACH33_10925	COG2996	Protein conserved in bacteria
ACH33_10930	COG0210	DNA helicase
ACH33_10935	COG0427	acetyl-CoA hydrolase
ACH33_10955	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
ACH33_10965	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
ACH33_10970	COG0517	IMP dehydrogenase activity
ACH33_10975	COG4980	gas vesicle protein
ACH33_10975	COG1674	ftsk spoiiie
ACH33_10980	COG1595	DNA-templated transcription, initiation
ACH33_10990	COG1131	(ABC) transporter
ACH33_11005	COG0442	prolyl-tRNA aminoacylation
ACH33_11040	COG3655	Transcriptional regulator
ACH33_11070	COG0582	viral genome integration into host DNA
ACH33_11080	COG0740	serine-type endopeptidase activity
ACH33_11085	COG0586	Pfam SNARE associated Golgi protein
ACH33_11110	COG1950	PFAM Membrane protein of
ACH33_11115	COG3723	Recombinational DNA repair protein, rece pathway
ACH33_11120	COG5377	YqaJ viral recombinase family
ACH33_11125	COG1396	sequence-specific DNA binding
ACH33_11130	COG0252	asparaginase activity
ACH33_11135	COG1115	amino acid carrier protein
ACH33_11145	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ACH33_11150	COG3829	transcription factor binding
ACH33_11155	COG1686	Belongs to the peptidase S11 family
ACH33_11160	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ACH33_11165	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
ACH33_11175	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACH33_11180	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ACH33_11190	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
ACH33_11195	COG1408	metallophosphoesterase
ACH33_11200	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ACH33_11205	COG0726	polysaccharide deacetylase
ACH33_11240	COG0739	heme binding
ACH33_11260	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ACH33_11280	COG0569	domain protein
ACH33_11280	COG0189	ligase activity
ACH33_11290	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACH33_11300	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACH33_11315	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACH33_11320	COG0602	queuosine metabolic process
ACH33_11340	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACH33_11345	COG1012	belongs to the aldehyde dehydrogenase family
ACH33_11365	COG3290	protein histidine kinase activity
ACH33_11365	COG3829	transcription factor binding
ACH33_11370	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACH33_11375	COG3938	Belongs to the proline racemase family
ACH33_11380	COG0531	amino acid
ACH33_11390	COG5002	protein histidine kinase activity
ACH33_11395	COG0745	RESPONSE REGULATOR receiver
ACH33_11400	COG2132	Multicopper oxidase
ACH33_11405	COG2217	Heavy metal translocating P-type atpase
ACH33_11455	COG2091	lysine biosynthetic process via aminoadipic acid
ACH33_11460	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ACH33_11470	COG0109	protoheme IX farnesyltransferase activity
ACH33_11475	COG1063	alcohol dehydrogenase
ACH33_11500	COG1151	hydroxylamine reductase activity
ACH33_11505	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ACH33_11545	COG2267	carboxylic ester hydrolase activity
ACH33_11565	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ACH33_11565	COG0473	3-isopropylmalate dehydrogenase activity
ACH33_11580	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACH33_11595	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
ACH33_11600	COG1181	Belongs to the D-alanine--D-alanine ligase family
ACH33_11675	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ACH33_11680	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ACH33_11725	COG0251	oxidation-reduction process
ACH33_11740	COG2368	4-hydroxyphenylacetate
ACH33_11900	COG0484	heat shock protein binding
ACH33_11915	COG3266	domain, Protein
ACH33_11915	COG0515	serine threonine protein kinase
ACH33_11940	COG1131	(ABC) transporter
ACH33_11950	COG4550	Control of competence regulator ComK, YlbF/YmcA
ACH33_11955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACH33_11970	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
ACH33_11975	COG1234	tRNA 3'-trailer cleavage
ACH33_11980	COG1013	pyruvate-flavodoxin oxidoreductase activity
ACH33_11985	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
ACH33_11985	COG0674	pyruvate-flavodoxin oxidoreductase activity
ACH33_11990	COG2359	stage V sporulation protein S
ACH33_11995	COG1692	metallophosphoesterase
ACH33_12000	COG1418	mRNA catabolic process
ACH33_12005	COG2137	regulation of response to DNA damage stimulus
ACH33_12010	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ACH33_12020	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
ACH33_12025	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ACH33_12030	COG0513	Belongs to the DEAD box helicase family
ACH33_12035	COG1546	Belongs to the CinA family
ACH33_12035	COG1058	Belongs to the CinA family
ACH33_12040	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ACH33_12045	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ACH33_12050	COG1426	Protein conserved in bacteria
ACH33_12065	COG0300	oxidoreductase activity
ACH33_12070	COG0612	Peptidase, M16
ACH33_12075	COG0612	Peptidase, M16
ACH33_12090	COG0515	serine threonine protein kinase
ACH33_12095	COG1132	(ABC) transporter
ACH33_12105	COG0574	Belongs to the PEP-utilizing enzyme family
ACH33_12105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACH33_12115	COG2801	Transposase and inactivated derivatives
ACH33_12125	COG3935	DnaD domain protein
ACH33_12135	COG0436	Aminotransferase
ACH33_12140	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACH33_12150	COG0675	Transposase, IS605 OrfB family
ACH33_12165	COG0402	S-adenosylhomocysteine deaminase activity
ACH33_12170	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
ACH33_12175	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ACH33_12175	COG1199	ATP-dependent helicase activity
ACH33_12185	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
ACH33_12190	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ACH33_12195	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ACH33_12200	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ACH33_12200	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ACH33_12205	COG0617	tRNA 3'-terminal CCA addition
ACH33_12210	COG0438	transferase activity, transferring glycosyl groups
ACH33_12215	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ACH33_12220	COG1803	Methylglyoxal synthase
ACH33_12225	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ACH33_12230	COG1694	Mazg nucleotide pyrophosphohydrolase
ACH33_12235	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ACH33_12290	COG1595	DNA-templated transcription, initiation
ACH33_12310	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ACH33_12315	COG0287	Prephenate dehydrogenase
ACH33_12320	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACH33_12325	COG0159	tryptophan synthase activity
ACH33_12330	COG0133	tryptophan synthase activity
ACH33_12335	COG0135	phosphoribosylanthranilate isomerase activity
ACH33_12340	COG0134	indole-3-glycerol-phosphate synthase activity
ACH33_12345	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ACH33_12360	COG4401	Chorismate mutase type I
ACH33_12365	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ACH33_12370	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ACH33_12375	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ACH33_12380	COG0105	UTP biosynthetic process
ACH33_12400	COG0109	protoheme IX farnesyltransferase activity
ACH33_12405	COG2226	methyltransferase
ACH33_12410	COG0142	geranyltranstransferase activity
ACH33_12420	COG0776	regulation of translation
ACH33_12430	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ACH33_12465	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ACH33_12470	COG1160	GTP binding
ACH33_12495	COG0539	negative regulation of cytoplasmic translation
ACH33_12505	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ACH33_12515	COG2959	enzyme of heme biosynthesis
ACH33_12520	COG2339	peptidase activity
ACH33_12525	COG0492	ferredoxin-NADP+ reductase activity
ACH33_12530	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ACH33_12535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ACH33_12540	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACH33_12545	COG3711	transcriptional antiterminator
ACH33_12555	COG0205	6-phosphofructokinase activity
ACH33_12560	COG1263	PTS System
ACH33_12560	COG2190	(PTS) system
ACH33_12560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACH33_12565	COG4862	establishment of competence for transformation
ACH33_12570	COG2357	RelA SpoT domain protein
ACH33_12575	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ACH33_12580	COG0492	ferredoxin-NADP+ reductase activity
ACH33_12600	COG0514	ATP-dependent DNA helicase (RecQ)
ACH33_12605	COG4955	Helix-turn-helix domain
ACH33_12610	COG1141	Ferredoxin
ACH33_12620	COG0598	Magnesium transport protein CorA
ACH33_12640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ACH33_12650	COG1028	Short-chain dehydrogenase reductase Sdr
ACH33_12655	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACH33_12660	COG2050	protein possibly involved in aromatic compounds catabolism
ACH33_12665	COG5002	protein histidine kinase activity
ACH33_12670	COG0745	RESPONSE REGULATOR receiver
ACH33_12675	COG0824	Thioesterase
ACH33_12685	COG5002	protein histidine kinase activity
ACH33_12690	COG0745	RESPONSE REGULATOR receiver
ACH33_12700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ACH33_12705	COG1333	cytochrome c biogenesis protein
ACH33_12710	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACH33_12720	COG1187	pseudouridine synthase activity
ACH33_12725	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ACH33_12730	COG2190	(PTS) system
ACH33_12740	COG0363	glucosamine-6-phosphate deaminase activity
ACH33_12750	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
ACH33_12750	COG1263	PTS System
ACH33_12750	COG2190	(PTS) system
ACH33_12755	COG0700	Nucleoside recognition
ACH33_12760	COG2715	membrane protein required for spore maturation
ACH33_12765	COG1686	Belongs to the peptidase S11 family
ACH33_12770	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ACH33_12775	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ACH33_12780	COG1994	Peptidase M50
ACH33_12785	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ACH33_12790	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACH33_12790	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ACH33_12800	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACH33_12800	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ACH33_12805	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ACH33_12810	COG0579	oxidoreductase
ACH33_12825	COG1012	belongs to the aldehyde dehydrogenase family
ACH33_12830	COG1113	amino acid transport
ACH33_12835	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACH33_12845	COG0537	adenosine 5'-monophosphoramidase activity
ACH33_12850	COG0019	diaminopimelate decarboxylase activity
ACH33_12865	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACH33_12890	COG2172	sigma factor antagonist activity
ACH33_12900	COG1686	Belongs to the peptidase S11 family
ACH33_12905	COG4608	Belongs to the ABC transporter superfamily
ACH33_12910	COG0444	Belongs to the ABC transporter superfamily
ACH33_12915	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ACH33_12920	COG0601	transmembrane transport
ACH33_12925	COG4166	transmembrane transport
ACH33_12930	COG1522	sequence-specific DNA binding
ACH33_12935	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ACH33_12945	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ACH33_12950	COG4974	Belongs to the 'phage' integrase family
ACH33_12965	COG0735	belongs to the Fur family
ACH33_12970	COG1300	Membrane
ACH33_12975	COG1379	DNA repair
ACH33_12980	COG0494	nUDIX hydrolase
ACH33_12990	COG2195	Cleaves the N-terminal amino acid of tripeptides
ACH33_12995	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ACH33_13000	COG0346	lactoylglutathione lyase activity
ACH33_13010	COG0508	dehydrogenase complex catalyzes the overall conversion of
ACH33_13015	COG0022	dehydrogenase e1 component
ACH33_13020	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ACH33_13025	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ACH33_13035	COG3290	protein histidine kinase activity
ACH33_13035	COG3829	transcription factor binding
ACH33_13050	COG0463	Glycosyl transferase, family 2
ACH33_13060	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACH33_13075	COG1253	flavin adenine dinucleotide binding
ACH33_13080	COG2738	Putative neutral zinc metallopeptidase
ACH33_13085	COG0789	Transcriptional regulator
ACH33_13095	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ACH33_13105	COG0681	Belongs to the peptidase S26 family
ACH33_13110	COG1012	belongs to the aldehyde dehydrogenase family
ACH33_13115	COG4848	Belongs to the UPF0354 family
ACH33_13130	COG1024	Enoyl-CoA hydratase
ACH33_13160	COG1392	Phosphate transport regulator
ACH33_13165	COG0306	phosphate transporter
ACH33_13180	COG2346	COG2346, Truncated hemoglobins
ACH33_13185	COG0741	lytic transglycosylase activity
ACH33_13190	COG0318	PFAM AMP-dependent synthetase and ligase
ACH33_13200	COG2154	pterin-4-alpha-carbinolamine dehydratase
ACH33_13205	COG2205	protein histidine kinase activity
ACH33_13205	COG2202	Pas domain
ACH33_13215	COG0784	Response regulator, receiver
ACH33_13215	COG2205	protein histidine kinase activity
ACH33_13215	COG5002	protein histidine kinase activity
ACH33_13220	COG1744	ABC transporter substrate-binding protein PnrA-like
ACH33_13225	COG2204	response regulator
ACH33_13230	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
ACH33_13230	COG0644	oxidoreductase
ACH33_13235	COG1309	transcriptional regulator
ACH33_13270	COG1277	ABC-type transport system involved in multi-copper enzyme maturation permease component
ACH33_13275	COG1131	(ABC) transporter
ACH33_13285	COG2423	ornithine cyclodeaminase activity
ACH33_13295	COG1476	TRANSCRIPTIONal
ACH33_13300	COG1396	sequence-specific DNA binding
ACH33_13305	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACH33_13310	COG0166	Belongs to the GPI family
ACH33_13315	COG0205	6-phosphofructokinase activity
ACH33_13320	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
ACH33_13330	COG0840	transmembrane signaling receptor activity
ACH33_13340	COG0477	Major facilitator Superfamily
ACH33_13345	COG1028	Short-chain dehydrogenase reductase Sdr
ACH33_13355	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACH33_13360	COG2610	gluconate transmembrane transporter activity
ACH33_13365	COG3829	transcription factor binding
ACH33_13365	COG3290	protein histidine kinase activity
ACH33_13370	COG0464	growth
ACH33_13410	COG0165	Argininosuccinate lyase
ACH33_13410	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
ACH33_13420	COG1902	pentaerythritol trinitrate reductase activity
ACH33_13430	COG1122	ATPase activity
ACH33_13435	COG4120	Belongs to the binding-protein-dependent transport system permease family
ACH33_13445	COG0564	pseudouridine synthase activity
ACH33_13450	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ACH33_13455	COG3874	Sporulation protein YtfJ
ACH33_13470	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACH33_13475	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACH33_13480	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACH33_13490	COG0861	Integral membrane protein TerC family
ACH33_13495	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ACH33_13510	COG0788	formyltetrahydrofolate deformylase activity
ACH33_13515	COG0302	gtp cyclohydrolase
ACH33_13550	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ACH33_13555	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
ACH33_13570	COG0004	ammonium transporteR
ACH33_13580	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
ACH33_13590	COG2259	Doxx family
ACH33_13605	COG0235	Class ii aldolase
ACH33_13610	COG2030	dehydratase
ACH33_13630	COG1028	Short-chain dehydrogenase reductase Sdr
ACH33_13635	COG3243	poly(R)-hydroxyalkanoic acid synthase
ACH33_13640	COG0301	tRNA thio-modification
ACH33_13645	COG1104	cysteine desulfurase activity
ACH33_13665	COG1473	amidohydrolase
ACH33_13670	COG1028	Short-chain dehydrogenase reductase Sdr
ACH33_13675	COG0300	oxidoreductase activity
ACH33_13680	COG2155	Conserved Protein
ACH33_13685	COG0386	Belongs to the glutathione peroxidase family
ACH33_13690	COG0531	amino acid
ACH33_13695	COG1595	DNA-templated transcription, initiation
ACH33_13710	COG0644	oxidoreductase
ACH33_13715	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
ACH33_13735	COG2081	HI0933 family
ACH33_13740	COG3162	membrane
ACH33_13745	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ACH33_13750	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
ACH33_13755	COG1309	transcriptional regulator
ACH33_13765	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ACH33_13770	COG2203	Gaf domain
ACH33_13770	COG2199	diguanylate cyclase activity
ACH33_13780	COG0133	tryptophan synthase activity
ACH33_13790	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ACH33_13795	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ACH33_13800	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACH33_13805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ACH33_13810	COG0454	-acetyltransferase
ACH33_13815	COG0517	IMP dehydrogenase activity
ACH33_13820	COG0123	including yeast histone deacetylase and acetoin utilization protein
ACH33_13825	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACH33_13840	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
ACH33_13840	COG1605	Chorismate mutase
ACH33_13850	COG3118	belongs to the thioredoxin family
ACH33_13865	COG0473	3-isopropylmalate dehydrogenase activity
ACH33_13885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ACH33_13890	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
ACH33_13900	COG0517	IMP dehydrogenase activity
ACH33_13930	COG3546	catalase activity
ACH33_13935	COG0778	Nitroreductase
ACH33_13950	COG0492	ferredoxin-NADP+ reductase activity
ACH33_14045	COG1686	Belongs to the peptidase S11 family
ACH33_14050	COG1028	Short-chain dehydrogenase reductase Sdr
ACH33_14060	COG0410	ABC transporter
ACH33_14065	COG0411	ABC transporter
ACH33_14075	COG0559	Belongs to the binding-protein-dependent transport system permease family
ACH33_14095	COG1012	belongs to the aldehyde dehydrogenase family
ACH33_14105	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ACH33_14115	COG0315	cyclic pyranopterin monophosphate synthase activity
ACH33_14120	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ACH33_14125	COG0697	spore germination
ACH33_14135	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ACH33_14145	COG1674	ftsk spoiiie
ACH33_14160	COG1297	OPT oligopeptide transporter protein
ACH33_14165	COG0129	dihydroxy-acid dehydratase activity
ACH33_14170	COG1376	ErfK ybiS ycfS ynhG family protein
ACH33_14175	COG2197	response regulator
ACH33_14180	COG4585	Histidine kinase
ACH33_14185	COG4758	membrane
ACH33_14195	COG1187	pseudouridine synthase activity
ACH33_14200	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
ACH33_14200	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
ACH33_14210	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ACH33_14220	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
ACH33_14225	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
ACH33_14230	COG0602	queuosine metabolic process
ACH33_14235	COG0720	synthase
ACH33_14240	COG0483	inositol monophosphate 1-phosphatase activity
ACH33_14245	COG2226	methyltransferase
ACH33_14260	COG0861	Integral membrane protein TerC family
ACH33_14270	COG0352	thiamine-phosphate diphosphorylase activity
ACH33_14275	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ACH33_14280	COG2104	thiamine diphosphate biosynthetic process
ACH33_14285	COG2022	thiamine diphosphate biosynthetic process
ACH33_14295	COG1924	4 iron, 4 sulfur cluster binding
ACH33_14300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ACH33_14315	COG2814	Major facilitator Superfamily
ACH33_14325	COG1408	metallophosphoesterase
ACH33_14340	COG1242	4 iron, 4 sulfur cluster binding
ACH33_14345	COG2707	UPF0756 membrane protein
ACH33_14355	COG1316	TRANSCRIPTIONal
ACH33_14360	COG2267	carboxylic ester hydrolase activity
ACH33_14395	COG1139	Iron-sulfur cluster binding protein
ACH33_14450	COG0371	Dehydrogenase
ACH33_14455	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACH33_14465	COG2362	D-Aminopeptidase
ACH33_14475	COG1464	Belongs to the NlpA lipoprotein family
ACH33_14480	COG2011	ABC-type metal ion transport system permease component
ACH33_14515	COG1879	ABC-type sugar transport system periplasmic component
ACH33_14520	COG1172	Belongs to the binding-protein-dependent transport system permease family
ACH33_14525	COG1129	ABC transporter
ACH33_14530	COG1869	D-ribose catabolic process
ACH33_14535	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ACH33_14540	COG1609	Transcriptional regulator
ACH33_14560	COG0688	phosphatidylethanolamine metabolic process
ACH33_14565	COG0702	epimerase
ACH33_14590	COG3335	DDE superfamily endonuclease
ACH33_14600	COG1832	CoA-binding protein
ACH33_14610	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ACH33_14620	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ACH33_14625	COG0840	transmembrane signaling receptor activity
ACH33_14630	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ACH33_14640	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
ACH33_14645	COG1484	DNA-dependent DNA replication
ACH33_14650	COG3611	Membrane attachment protein
ACH33_14655	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ACH33_14660	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ACH33_14665	COG0741	lytic transglycosylase activity
ACH33_14665	COG0739	heme binding
ACH33_14665	COG1196	nuclear chromosome segregation
ACH33_14670	COG0237	dephospho-CoA kinase activity
ACH33_14675	COG1971	Probably functions as a manganese efflux pump
ACH33_14680	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ACH33_14685	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACH33_14685	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ACH33_14690	COG0330	HflC and HflK could
ACH33_14700	COG5002	protein histidine kinase activity
ACH33_14705	COG0745	RESPONSE REGULATOR receiver
ACH33_14725	COG0039	L-malate dehydrogenase activity
ACH33_14730	COG0538	isocitrate dehydrogenase activity
ACH33_14735	COG0372	Belongs to the citrate synthase family
ACH33_14745	COG0628	permease
ACH33_14750	COG3030	protein affecting phage T7 exclusion by the F plasmid
ACH33_14755	COG0824	Thioesterase
ACH33_14765	COG0825	malonyl-CoA metabolic process
ACH33_14770	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ACH33_14780	COG2186	Transcriptional regulator
ACH33_14785	COG0281	malic enzyme
ACH33_14790	COG0587	DNA-directed DNA polymerase activity
ACH33_14815	COG4109	DRTGG domain
ACH33_14825	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ACH33_14835	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ACH33_14840	COG0189	ligase activity
ACH33_14845	COG0189	ligase activity
ACH33_14850	COG0189	ligase activity
ACH33_14875	COG0436	Aminotransferase
ACH33_14880	COG1683	Conserved Protein
ACH33_14885	COG1937	Protein conserved in bacteria
ACH33_14895	COG1741	Belongs to the pirin family
ACH33_14915	COG3384	dioxygenase
ACH33_14925	COG2719	SpoVR family
ACH33_14940	COG3335	DDE superfamily endonuclease
ACH33_14950	COG1876	peptidase activity
ACH33_14955	COG4824	toxin secretion phage lysis holin
ACH33_15120	COG2766	serine protein kinase
ACH33_15130	COG1464	Belongs to the NlpA lipoprotein family
ACH33_15145	COG1714	RDD family
ACH33_15150	COG0616	signal peptide processing
ACH33_15160	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ACH33_15170	COG0328	RNA-DNA hybrid ribonuclease activity
ACH33_15180	COG2233	PERMEase
ACH33_15185	COG1573	uracil-dna glycosylase
ACH33_15195	COG1573	uracil-dna glycosylase
ACH33_15305	COG0735	belongs to the Fur family
ACH33_15345	COG2096	Adenosyltransferase
ACH33_15355	COG2226	methyltransferase
ACH33_15360	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ACH33_15390	COG4555	ABC transporter
ACH33_15395	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
ACH33_15400	COG0067	glutamate synthase
ACH33_15400	COG0069	glutamate synthase activity
ACH33_15400	COG0070	glutamate synthase
ACH33_15410	COG1850	ribulose-bisphosphate carboxylase activity
ACH33_15415	COG4359	Dephosphorylates 2-hydroxy-3-keto-5-methylthiopentenyl- 1-phosphate (HK-MTPenyl-1-P) yielding 1,2-dihydroxy-3-keto-5- methylthiopentene (DHK-MTPene)
ACH33_15420	COG0235	Class ii aldolase
ACH33_15425	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
ACH33_15430	COG2249	NAD(P)H dehydrogenase (quinone) activity
ACH33_15435	COG1132	(ABC) transporter
ACH33_15440	COG3557	Belongs to the UPF0374 family
ACH33_15445	COG0456	acetyltransferase
ACH33_15465	COG0670	Belongs to the BI1 family
ACH33_15470	COG2814	Major facilitator Superfamily
ACH33_15475	COG0247	lactate metabolic process
ACH33_15480	COG0277	FAD linked oxidase domain protein
ACH33_15495	COG1988	membrane-bound metal-dependent
ACH33_15505	COG2340	Cysteine-rich secretory protein family
ACH33_15510	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ACH33_15515	COG0534	Mate efflux family protein
ACH33_15525	COG0529	Catalyzes the synthesis of activated sulfate
ACH33_15530	COG2046	Belongs to the sulfate adenylyltransferase family
ACH33_15535	COG0175	sulfate reduction
ACH33_15540	COG0306	phosphate transporter
ACH33_15550	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ACH33_15560	COG0577	efflux transmembrane transporter activity
ACH33_15565	COG1136	(ABC) transporter
ACH33_15575	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ACH33_15580	COG1012	belongs to the aldehyde dehydrogenase family
ACH33_15585	COG3290	protein histidine kinase activity
ACH33_15585	COG3829	transcription factor binding
ACH33_15605	COG0697	spore germination
ACH33_15620	COG1929	Belongs to the glycerate kinase type-1 family
ACH33_15625	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ACH33_15635	COG1183	phosphatidylcholine synthase activity
ACH33_15640	COG1113	amino acid transport
ACH33_15645	COG1960	acyl-CoA dehydrogenase activity
ACH33_15650	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ACH33_15665	COG4191	Histidine kinase
ACH33_15675	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACH33_15680	COG0500	methyltransferase
ACH33_15680	COG3615	Tellurite resistance protein tehB
ACH33_15685	COG0827	DNA restriction-modification system
ACH33_15690	COG0827	DNA restriction-modification system
ACH33_15695	COG1280	lysine exporter protein (LysE YggA)
ACH33_15715	COG2801	Transposase and inactivated derivatives
ACH33_15730	COG3335	DDE superfamily endonuclease
ACH33_15735	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACH33_15755	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ACH33_15815	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ACH33_15820	COG4840	Belongs to the UPF0435 family
ACH33_15825	COG0733	neurotransmitter:sodium symporter activity
ACH33_15830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ACH33_15840	COG0733	neurotransmitter:sodium symporter activity
ACH33_15845	COG0598	Magnesium transport protein CorA
ACH33_15860	COG2323	membrane
ACH33_15870	COG1131	(ABC) transporter
ACH33_15875	COG1132	(ABC) transporter
ACH33_15880	COG0535	radical SAM domain protein
ACH33_15885	COG2259	Doxx family
ACH33_15905	COG1823	symporter activity
ACH33_15910	COG0531	amino acid
ACH33_15920	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ACH33_15925	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
ACH33_15950	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
ACH33_15965	COG1203	CRISPR-associated helicase, Cas3
ACH33_15990	COG3104	oligopeptide transport
ACH33_16020	COG3775	system Galactitol-specific IIC component
ACH33_16035	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
ACH33_16100	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ACH33_16105	COG1597	lipid kinase activity
ACH33_16110	COG3852	Histidine kinase
ACH33_16115	COG1396	sequence-specific DNA binding
ACH33_16120	COG0247	lactate metabolic process
ACH33_16125	COG0277	FAD linked oxidase domain protein
ACH33_16130	COG2186	Transcriptional regulator
ACH33_16140	COG3706	GGDEF domain
ACH33_16145	COG0582	viral genome integration into host DNA
ACH33_16155	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACH33_16160	COG0154	amidase activity
ACH33_16165	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ACH33_16170	COG0840	transmembrane signaling receptor activity
ACH33_16185	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ACH33_16190	COG0210	DNA helicase
ACH33_16205	COG1131	(ABC) transporter
ACH33_16225	COG4496	protein, YerC YecD
ACH33_16230	COG0675	Transposase, IS605 OrfB family
ACH33_16235	COG0840	transmembrane signaling receptor activity
ACH33_16240	COG1470	cell adhesion involved in biofilm formation
ACH33_16250	COG0411	ABC transporter
ACH33_16260	COG0559	Belongs to the binding-protein-dependent transport system permease family
ACH33_16275	COG0151	Belongs to the GarS family
ACH33_16285	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ACH33_16290	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ACH33_16295	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ACH33_16300	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACH33_16305	COG0047	phosphoribosylformylglycinamidine synthase activity
ACH33_16310	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ACH33_16315	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ACH33_16320	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ACH33_16325	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ACH33_16330	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ACH33_16335	COG3437	response regulator, receiver
ACH33_16340	COG2252	PERMEase
ACH33_16345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ACH33_16345	COG0519	Catalyzes the synthesis of GMP from XMP
ACH33_16355	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ACH33_16360	COG0805	protein transport
ACH33_16365	COG0521	Mo-molybdopterin cofactor biosynthetic process
ACH33_16370	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ACH33_16375	COG0488	(ABC) transporter
ACH33_16390	COG0456	acetyltransferase
ACH33_16395	COG1214	PFAM Peptidase M22, glycoprotease
ACH33_16400	COG0802	atpase or kinase
ACH33_16405	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
ACH33_16410	COG3091	SprT-like family
ACH33_16420	COG2183	response to ionizing radiation
ACH33_16425	COG2337	Toxic component of a toxin-antitoxin (TA) module
ACH33_16430	COG0864	Transcriptional regulator
ACH33_16435	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ACH33_16545	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
ACH33_16550	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
ACH33_16550	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ACH33_16555	COG0736	holo-[acyl-carrier-protein] synthase activity
ACH33_16560	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACH33_16565	COG1294	oxidase, subunit
ACH33_16570	COG1360	Flagellar Motor Protein
ACH33_16580	COG0454	-acetyltransferase
ACH33_16590	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACH33_16595	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ACH33_16600	COG0586	Pfam SNARE associated Golgi protein
ACH33_16605	COG1316	TRANSCRIPTIONal
ACH33_16620	COG0463	Glycosyl transferase, family 2
ACH33_16625	COG0785	Cytochrome C biogenesis protein
ACH33_16630	COG3279	Response regulator of the LytR AlgR family
ACH33_16635	COG4512	PFAM Accessory gene regulator B
ACH33_16650	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ACH33_16655	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
ACH33_16660	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
ACH33_16665	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ACH33_16670	COG2508	Transcriptional regulator
ACH33_16670	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
ACH33_16680	COG3829	transcription factor binding
ACH33_16685	COG1509	lysine 2,3-aminomutase activity
ACH33_16700	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ACH33_16715	COG2323	membrane
ACH33_16725	COG0071	Belongs to the small heat shock protein (HSP20) family
ACH33_16730	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ACH33_16735	COG0840	transmembrane signaling receptor activity
ACH33_16805	COG3335	DDE superfamily endonuclease
ACH33_16865	COG1876	peptidase activity
ACH33_16870	COG4824	toxin secretion phage lysis holin
ACH33_16915	COG1484	DNA-dependent DNA replication
ACH33_16955	COG1396	sequence-specific DNA binding
ACH33_16960	COG0735	belongs to the Fur family
ACH33_16965	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ACH33_16970	COG1121	(ABC) transporter
ACH33_16975	COG0803	Belongs to the bacterial solute-binding protein 9 family
ACH33_16985	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ACH33_16990	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
ACH33_17020	COG1595	DNA-templated transcription, initiation
ACH33_17030	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ACH33_17035	COG2205	protein histidine kinase activity
ACH33_17040	COG0745	RESPONSE REGULATOR receiver
ACH33_17050	COG3290	protein histidine kinase activity
ACH33_17050	COG3829	transcription factor binding
ACH33_17075	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACH33_17100	COG0477	Major facilitator Superfamily
ACH33_17105	COG0531	amino acid
ACH33_17115	COG2427	Protein of unknown function (DUF1641)
ACH33_17120	COG3383	formate dehydrogenase (NAD+) activity
ACH33_17125	COG4948	Mandelate Racemase Muconate Lactonizing
ACH33_17140	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ACH33_17145	COG0367	asparagine synthase
ACH33_17255	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
ACH33_17260	COG1024	Enoyl-CoA hydratase
ACH33_17265	COG1115	amino acid carrier protein
ACH33_17270	COG0288	reversible hydration of carbon dioxide
ACH33_17280	COG0450	alkyl hydroperoxide reductase
ACH33_17315	COG2205	protein histidine kinase activity
ACH33_17320	COG0745	RESPONSE REGULATOR receiver
ACH33_17340	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ACH33_17345	COG4856	YbbR-like protein
ACH33_17350	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
ACH33_17355	COG5662	AntiSigma factor
ACH33_17360	COG1595	DNA-templated transcription, initiation
ACH33_17365	COG0010	Belongs to the arginase family
ACH33_17465	COG0726	polysaccharide deacetylase
ACH33_17470	COG2194	sulfuric ester hydrolase activity
ACH33_17480	COG0489	protein tyrosine kinase activity
ACH33_17485	COG0860	N-Acetylmuramoyl-L-alanine amidase
ACH33_17495	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ACH33_17500	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ACH33_17505	COG0101	tRNA pseudouridine synthase activity
ACH33_17515	COG1122	ATPase activity
ACH33_17520	COG1122	ATPase activity
ACH33_17525	COG0203	ribosomal protein L17
ACH33_17530	COG0202	RNA polymerase activity
ACH33_17535	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ACH33_17540	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ACH33_17545	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ACH33_17550	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ACH33_17555	COG0024	Methionine aminopeptidase
ACH33_17560	COG0563	adenylate kinase activity
ACH33_17565	COG0201	protein transport
ACH33_17570	COG0200	Binds to the 23S rRNA
ACH33_17575	COG1841	ribosomal large subunit assembly
ACH33_17580	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ACH33_17585	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ACH33_17590	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ACH33_17595	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ACH33_17600	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ACH33_17605	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ACH33_17615	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
ACH33_17620	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ACH33_17625	COG0255	Belongs to the universal ribosomal protein uL29 family
ACH33_17630	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ACH33_17635	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ACH33_17645	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ACH33_17650	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ACH33_17655	COG0089	rRNA binding
ACH33_17660	COG0088	Forms part of the polypeptide exit tunnel
ACH33_17665	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ACH33_17670	COG0051	transcription antitermination factor activity, RNA binding
ACH33_17690	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ACH33_17700	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ACH33_17705	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ACH33_17710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ACH33_17715	COG2271	Major facilitator Superfamily
ACH33_17720	COG1954	Regulates expression of the glpD operon. In the presence of glycerol 3-phosphate (G3P) causes antitermination of transcription of glpD at the inverted repeat of the leader region to enhance its transcription. Binds and stabilizes glpD leader mRNA
ACH33_17770	COG0531	amino acid
ACH33_17785	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ACH33_17790	COG0179	Fumarylacetoacetate (FAA) hydrolase
ACH33_17795	COG3185	4-Hydroxyphenylpyruvate dioxygenase
ACH33_17850	COG0704	Plays a role in the regulation of phosphate uptake
ACH33_17855	COG0772	Belongs to the SEDS family
ACH33_17860	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ACH33_17865	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ACH33_17870	COG0049	tRNA binding
ACH33_17875	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ACH33_17880	COG1358	cellular component organization or biogenesis
ACH33_17885	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ACH33_17890	COG0085	RNA polymerase activity
ACH33_17895	COG2813	Specifically methylates the guanine in position
ACH33_17900	COG0222	ribosome binding
ACH33_17905	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ACH33_17910	COG0081	regulation of translation
ACH33_17915	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ACH33_17920	COG0250	Participates in transcription elongation, termination and antitermination
ACH33_17925	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ACH33_17930	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ACH33_17935	COG0840	transmembrane signaling receptor activity
ACH33_17945	COG3688	RNA-binding protein containing a PIN domain
ACH33_17950	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ACH33_17955	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
ACH33_17960	COG0215	cysteine-tRNA ligase activity
ACH33_17965	COG1045	serine acetyltransferase
ACH33_17970	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ACH33_17980	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ACH33_17985	COG4956	integral membrane protein (PIN domain superfamily)
ACH33_17990	COG1329	Transcriptional regulator
ACH33_17995	COG1183	phosphatidylcholine synthase activity
ACH33_18000	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
ACH33_18005	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
ACH33_18010	COG0542	response to heat
ACH33_18015	COG3869	Catalyzes the specific phosphorylation of arginine residues in
ACH33_18020	COG3880	PFAM UvrB UvrC protein
ACH33_18030	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ACH33_18035	COG0581	inorganic phosphate transmembrane transporter activity
ACH33_18040	COG0573	inorganic phosphate transmembrane transporter activity
ACH33_18050	COG4948	Mandelate Racemase Muconate Lactonizing
ACH33_18060	COG1473	amidohydrolase
ACH33_18095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ACH33_18100	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ACH33_18105	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ACH33_18110	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ACH33_18115	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ACH33_18120	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ACH33_18125	COG0512	Glutamine amidotransferase of anthranilate synthase
ACH33_18130	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ACH33_18135	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ACH33_18140	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ACH33_18155	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ACH33_18160	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ACH33_18165	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ACH33_18175	COG0037	tRNA processing
ACH33_18185	COG2208	phosphoserine phosphatase activity
ACH33_18205	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ACH33_18210	COG3956	TIGRFAM MazG family protein
ACH33_18215	COG2244	polysaccharide biosynthetic process
ACH33_18225	COG2002	toxin-antitoxin pair type II binding
ACH33_18235	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ACH33_18245	COG0193	aminoacyl-tRNA hydrolase activity
ACH33_18250	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ACH33_18255	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
ACH33_18260	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ACH33_18265	COG2088	sporulation resulting in formation of a cellular spore
ACH33_18270	COG0251	oxidation-reduction process
ACH33_18275	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
ACH33_18280	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ACH33_18290	COG4466	Protein conserved in bacteria
ACH33_18300	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ACH33_18310	COG3583	domain protein
ACH33_18310	COG3584	3D domain protein
ACH33_18315	COG0084	hydrolase, TatD family'
ACH33_18320	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACH33_18320	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ACH33_18325	COG2002	toxin-antitoxin pair type II binding
ACH33_18330	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ACH33_18335	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
ACH33_18340	COG4467	Involved in initiation control of chromosome replication
ACH33_18345	COG1774	PSP1 C-terminal conserved region
ACH33_18355	COG1728	Protein conserved in bacteria
ACH33_18360	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ACH33_18365	COG1982	Orn Lys Arg decarboxylase major