AFK25_14600 8d544dc921ca66b3a7d347e3f2140a61 65 PIRSF PIRSF037263 1 65 8.1E-35 T 11-10-2018 IPR009296 Protein of unknown function DUF951 AFK25_14600 8d544dc921ca66b3a7d347e3f2140a61 65 Pfam PF06107 Bacterial protein of unknown function (DUF951) 6 59 1.9E-30 T 11-10-2018 IPR009296 Protein of unknown function DUF951 AFK25_13945 7ee206a31537173bf054f437972951ce 66 ProSitePatterns PS01143 Ribosomal protein L31 signature. 34 55 - T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_13945 7ee206a31537173bf054f437972951ce 66 TIGRFAM TIGR00105 L31: ribosomal protein bL31 1 65 1.9E-30 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_13945 7ee206a31537173bf054f437972951ce 66 Gene3D G3DSA:2.30.170.50 1 66 2.9E-32 T 11-10-2018 AFK25_13945 7ee206a31537173bf054f437972951ce 66 PRINTS PR01249 Ribosomal protein L31 signature 45 63 2.2E-22 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_13945 7ee206a31537173bf054f437972951ce 66 PRINTS PR01249 Ribosomal protein L31 signature 2 19 2.2E-22 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_13945 7ee206a31537173bf054f437972951ce 66 PRINTS PR01249 Ribosomal protein L31 signature 30 45 2.2E-22 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_13945 7ee206a31537173bf054f437972951ce 66 SUPERFAMILY SSF143800 1 65 7.06E-26 T 11-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_13945 7ee206a31537173bf054f437972951ce 66 Hamap MF_00501 50S ribosomal protein L31 [rpmE]. 1 66 27.977 T 11-10-2018 IPR027491 Ribosomal protein L31 type A GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_13945 7ee206a31537173bf054f437972951ce 66 Pfam PF01197 Ribosomal protein L31 1 64 4.2E-32 T 11-10-2018 IPR002150 Ribosomal protein L31 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_09415 bb6994a1a71787a6beb9c2827a3dacee 116 TIGRFAM TIGR02886 spore_II_AA: anti-sigma F factor antagonist 5 110 2.2E-46 T 11-10-2018 IPR014237 Anti-sigma F factor antagonist GO:0006355|GO:0030435|GO:0045152 AFK25_09415 bb6994a1a71787a6beb9c2827a3dacee 116 Pfam PF01740 STAS domain 5 104 2.6E-23 T 11-10-2018 IPR002645 STAS domain AFK25_09415 bb6994a1a71787a6beb9c2827a3dacee 116 Gene3D G3DSA:3.30.750.24 2 116 4.6E-32 T 11-10-2018 IPR036513 STAS domain superfamily AFK25_09415 bb6994a1a71787a6beb9c2827a3dacee 116 TIGRFAM TIGR00377 ant_ant_sig: anti-anti-sigma factor 2 103 1.4E-36 T 11-10-2018 IPR003658 Anti-sigma factor antagonist GO:0006355|GO:0045152 AFK25_09415 bb6994a1a71787a6beb9c2827a3dacee 116 SUPERFAMILY SSF52091 3 113 4.91E-30 T 11-10-2018 IPR036513 STAS domain superfamily AFK25_05805 d50504b9e512ec10993af3c46ff86cd5 246 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 16 241 8.5E-33 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFK25_05805 d50504b9e512ec10993af3c46ff86cd5 246 Pfam PF04545 Sigma-70, region 4 192 240 6.8E-16 T 11-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFK25_05805 d50504b9e512ec10993af3c46ff86cd5 246 Gene3D G3DSA:1.20.140.160 92 245 9.6E-46 T 11-10-2018 AFK25_05805 d50504b9e512ec10993af3c46ff86cd5 246 Gene3D G3DSA:1.10.1740.10 8 90 6.2E-27 T 11-10-2018 AFK25_05805 d50504b9e512ec10993af3c46ff86cd5 246 PIRSF PIRSF000770 11 246 1.3E-42 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05805 d50504b9e512ec10993af3c46ff86cd5 246 SUPERFAMILY SSF88946 4 93 9.73E-25 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_05805 d50504b9e512ec10993af3c46ff86cd5 246 SUPERFAMILY SSF88659 157 243 1.87E-21 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFK25_05805 d50504b9e512ec10993af3c46ff86cd5 246 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 212 238 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05805 d50504b9e512ec10993af3c46ff86cd5 246 SUPERFAMILY SSF88659 94 164 1.09E-15 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFK25_05805 d50504b9e512ec10993af3c46ff86cd5 246 PRINTS PR00046 Major sigma-70 factor signature 48 61 1.2E-9 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05805 d50504b9e512ec10993af3c46ff86cd5 246 PRINTS PR00046 Major sigma-70 factor signature 227 238 1.2E-9 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05805 d50504b9e512ec10993af3c46ff86cd5 246 PRINTS PR00046 Major sigma-70 factor signature 195 207 1.2E-9 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05805 d50504b9e512ec10993af3c46ff86cd5 246 PRINTS PR00046 Major sigma-70 factor signature 212 227 1.2E-9 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05805 d50504b9e512ec10993af3c46ff86cd5 246 PRINTS PR00046 Major sigma-70 factor signature 72 80 1.2E-9 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05805 d50504b9e512ec10993af3c46ff86cd5 246 Pfam PF04542 Sigma-70 region 2 21 93 1.7E-13 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_05805 d50504b9e512ec10993af3c46ff86cd5 246 TIGRFAM TIGR02479 FliA_WhiG: RNA polymerase sigma factor, FliA/WhiG family 21 241 3.4E-79 T 11-10-2018 IPR012845 RNA polymerase sigma factor, FliA/WhiG GO:0003677|GO:0003899|GO:0006352|GO:0006355|GO:0016987 AFK25_05805 d50504b9e512ec10993af3c46ff86cd5 246 Pfam PF04539 Sigma-70 region 3 100 178 6.6E-12 T 11-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 AFK25_03325 b269f9f44f2117d0d46817f2fabea038 321 SUPERFAMILY SSF53822 44 253 8.54E-14 T 11-10-2018 IPR028082 Periplasmic binding protein-like I AFK25_03325 b269f9f44f2117d0d46817f2fabea038 321 Gene3D G3DSA:3.40.50.2300 36 286 8.1E-91 T 11-10-2018 AFK25_03325 b269f9f44f2117d0d46817f2fabea038 321 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 36 314 2.0E-67 T 11-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 AFK25_03325 b269f9f44f2117d0d46817f2fabea038 321 Gene3D G3DSA:3.40.50.2300 133 318 8.1E-91 T 11-10-2018 AFK25_01215 448e18e41a2f3d44dcb7e92a2e5977c8 337 Gene3D G3DSA:3.30.420.40 8 321 1.5E-124 T 11-10-2018 AFK25_01215 448e18e41a2f3d44dcb7e92a2e5977c8 337 TIGRFAM TIGR03723 T6A_TsaD_YgjD: tRNA threonylcarbamoyl adenosine modification protein TsaD 8 319 8.3E-134 T 11-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 AFK25_01215 448e18e41a2f3d44dcb7e92a2e5977c8 337 Gene3D G3DSA:3.30.420.40 133 299 1.5E-124 T 11-10-2018 AFK25_01215 448e18e41a2f3d44dcb7e92a2e5977c8 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 102 121 3.1E-50 T 11-10-2018 IPR017861 Kae1/TsaD family AFK25_01215 448e18e41a2f3d44dcb7e92a2e5977c8 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 135 147 3.1E-50 T 11-10-2018 IPR017861 Kae1/TsaD family AFK25_01215 448e18e41a2f3d44dcb7e92a2e5977c8 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 9 22 3.1E-50 T 11-10-2018 IPR017861 Kae1/TsaD family AFK25_01215 448e18e41a2f3d44dcb7e92a2e5977c8 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 268 277 3.1E-50 T 11-10-2018 IPR017861 Kae1/TsaD family AFK25_01215 448e18e41a2f3d44dcb7e92a2e5977c8 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 158 179 3.1E-50 T 11-10-2018 IPR017861 Kae1/TsaD family AFK25_01215 448e18e41a2f3d44dcb7e92a2e5977c8 337 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 81 101 3.1E-50 T 11-10-2018 IPR017861 Kae1/TsaD family AFK25_01215 448e18e41a2f3d44dcb7e92a2e5977c8 337 Pfam PF00814 Glycoprotease family 28 312 8.2E-105 T 11-10-2018 IPR000905 Gcp-like domain AFK25_01215 448e18e41a2f3d44dcb7e92a2e5977c8 337 Hamap MF_01445 tRNA N6-adenosine threonylcarbamoyltransferase [tsaD]. 6 337 62.236 T 11-10-2018 IPR022450 tRNA N6-adenosine threonylcarbamoyltransferase, TsaD GO:0002949|GO:0004222 AFK25_01215 448e18e41a2f3d44dcb7e92a2e5977c8 337 SUPERFAMILY SSF53067 106 314 1.33E-43 T 11-10-2018 AFK25_01215 448e18e41a2f3d44dcb7e92a2e5977c8 337 SUPERFAMILY SSF53067 8 127 9.71E-32 T 11-10-2018 AFK25_01215 448e18e41a2f3d44dcb7e92a2e5977c8 337 ProSitePatterns PS01016 Glycoprotease family signature. 101 121 - T 11-10-2018 IPR017860 Peptidase M22, conserved site Reactome: R-HSA-6782315 AFK25_01215 448e18e41a2f3d44dcb7e92a2e5977c8 337 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 9 312 7.0E-110 T 11-10-2018 IPR017861 Kae1/TsaD family AFK25_11340 7ae73884b58b912bde478efca7d506c6 781 SMART SM00463 703 781 8.5E-23 T 11-10-2018 IPR002625 Smr domain AFK25_11340 7ae73884b58b912bde478efca7d506c6 781 TIGRFAM TIGR01069 mutS2: MutS2 family protein 4 780 1.1E-276 T 11-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 AFK25_11340 7ae73884b58b912bde478efca7d506c6 781 Gene3D G3DSA:3.40.50.300 289 595 4.5E-86 T 11-10-2018 AFK25_11340 7ae73884b58b912bde478efca7d506c6 781 Gene3D G3DSA:3.30.1370.110 695 781 2.1E-23 T 11-10-2018 AFK25_11340 7ae73884b58b912bde478efca7d506c6 781 SUPERFAMILY SSF48334 34 284 1.27E-29 T 11-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily AFK25_11340 7ae73884b58b912bde478efca7d506c6 781 SMART SM00533 9 312 5.4E-29 T 11-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 AFK25_11340 7ae73884b58b912bde478efca7d506c6 781 Hamap MF_00092 Endonuclease MutS2 [mutS2]. 2 780 22.557 T 11-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 AFK25_11340 7ae73884b58b912bde478efca7d506c6 781 Gene3D G3DSA:1.10.1420.10 111 223 3.3E-9 T 11-10-2018 AFK25_11340 7ae73884b58b912bde478efca7d506c6 781 SUPERFAMILY SSF52540 289 512 6.23E-47 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_11340 7ae73884b58b912bde478efca7d506c6 781 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 407 423 - T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 AFK25_11340 7ae73884b58b912bde478efca7d506c6 781 SUPERFAMILY SSF160443 704 780 6.02E-10 T 11-10-2018 IPR036063 Smr domain superfamily AFK25_11340 7ae73884b58b912bde478efca7d506c6 781 PIRSF PIRSF005814 1 781 2.5E-281 T 11-10-2018 IPR005747 Endonuclease MutS2 GO:0004519|GO:0016887|GO:0030983|GO:0045910 AFK25_11340 7ae73884b58b912bde478efca7d506c6 781 Pfam PF00488 MutS domain V 328 509 8.7E-34 T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 AFK25_11340 7ae73884b58b912bde478efca7d506c6 781 Pfam PF01713 Smr domain 706 780 4.2E-20 T 11-10-2018 IPR002625 Smr domain AFK25_11340 7ae73884b58b912bde478efca7d506c6 781 Gene3D G3DSA:1.10.1420.10 65 278 3.3E-9 T 11-10-2018 AFK25_11340 7ae73884b58b912bde478efca7d506c6 781 SMART SM00534 325 510 1.2E-78 T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 AFK25_00020 5c45d45a82dec35c786e722a2d9e6680 371 ProSitePatterns PS00617 RecF protein signature 1. 116 136 - T 11-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 AFK25_00020 5c45d45a82dec35c786e722a2d9e6680 371 Gene3D G3DSA:3.40.50.300 6 345 2.0E-110 T 11-10-2018 AFK25_00020 5c45d45a82dec35c786e722a2d9e6680 371 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 346 5.1E-17 T 11-10-2018 IPR003395 RecF/RecN/SMC, N-terminal AFK25_00020 5c45d45a82dec35c786e722a2d9e6680 371 ProSitePatterns PS00618 RecF protein signature 2. 312 330 - T 11-10-2018 IPR018078 DNA-binding, RecF, conserved site GO:0003697|GO:0005524|GO:0006281 AFK25_00020 5c45d45a82dec35c786e722a2d9e6680 371 TIGRFAM TIGR00611 recf: DNA replication and repair protein RecF 2 362 6.7E-126 T 11-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 AFK25_00020 5c45d45a82dec35c786e722a2d9e6680 371 Hamap MF_00365 DNA replication and repair protein RecF [recF]. 1 371 101.937 T 11-10-2018 IPR001238 DNA-binding, RecF GO:0003697|GO:0005524|GO:0006281 AFK25_00020 5c45d45a82dec35c786e722a2d9e6680 371 Gene3D G3DSA:1.20.1050.90 119 311 2.0E-110 T 11-10-2018 AFK25_00020 5c45d45a82dec35c786e722a2d9e6680 371 SUPERFAMILY SSF52540 2 352 2.4E-40 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_14235 58f434b02e942d07a43c4d5f3ab5bd74 456 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 153 439 5.7E-92 T 11-10-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 AFK25_14235 58f434b02e942d07a43c4d5f3ab5bd74 456 SUPERFAMILY SSF55604 7 81 4.05E-21 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 AFK25_14235 58f434b02e942d07a43c4d5f3ab5bd74 456 Pfam PF00367 phosphotransferase system, EIIB 8 41 2.2E-15 T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 AFK25_14235 58f434b02e942d07a43c4d5f3ab5bd74 456 Pfam PF02378 Phosphotransferase system, EIIC 110 394 6.5E-56 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 AFK25_14235 58f434b02e942d07a43c4d5f3ab5bd74 456 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 2 450 4.6E-194 T 11-10-2018 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 AFK25_14235 58f434b02e942d07a43c4d5f3ab5bd74 456 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 19 36 - T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 AFK25_14235 58f434b02e942d07a43c4d5f3ab5bd74 456 Gene3D G3DSA:3.30.1360.60 1 77 4.5E-28 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 AFK25_14235 58f434b02e942d07a43c4d5f3ab5bd74 456 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 28 111 2.0E-17 T 11-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 AFK25_08260 6fb16fd2e3f969571e21caa59c5009ab 431 Pfam PF12831 FAD dependent oxidoreductase 6 155 5.7E-9 T 11-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal AFK25_08260 6fb16fd2e3f969571e21caa59c5009ab 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 153 168 1.9E-9 T 11-10-2018 AFK25_08260 6fb16fd2e3f969571e21caa59c5009ab 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 295 310 1.9E-9 T 11-10-2018 AFK25_08260 6fb16fd2e3f969571e21caa59c5009ab 431 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 6 28 1.9E-9 T 11-10-2018 AFK25_08260 6fb16fd2e3f969571e21caa59c5009ab 431 SUPERFAMILY SSF54373 182 284 3.02E-19 T 11-10-2018 AFK25_08260 6fb16fd2e3f969571e21caa59c5009ab 431 Gene3D G3DSA:3.50.50.60 2 431 1.2E-76 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_08260 6fb16fd2e3f969571e21caa59c5009ab 431 SUPERFAMILY SSF51905 1 368 1.15E-44 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_06805 bf2a8c246c56e272413cb2cc18473c68 309 Gene3D G3DSA:3.40.50.300 23 220 2.4E-59 T 11-10-2018 AFK25_06805 bf2a8c246c56e272413cb2cc18473c68 309 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 89 199 1.3E-18 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFK25_06805 bf2a8c246c56e272413cb2cc18473c68 309 SMART SM00382 85 223 2.3E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_06805 bf2a8c246c56e272413cb2cc18473c68 309 Gene3D G3DSA:1.10.8.60 221 309 8.0E-22 T 11-10-2018 AFK25_06805 bf2a8c246c56e272413cb2cc18473c68 309 PRINTS PR00819 CbxX/CfqX superfamily signature 48 62 8.4E-60 T 11-10-2018 IPR000641 CbxX/CfqX GO:0005524 AFK25_06805 bf2a8c246c56e272413cb2cc18473c68 309 PRINTS PR00819 CbxX/CfqX superfamily signature 208 227 8.4E-60 T 11-10-2018 IPR000641 CbxX/CfqX GO:0005524 AFK25_06805 bf2a8c246c56e272413cb2cc18473c68 309 PRINTS PR00819 CbxX/CfqX superfamily signature 268 280 8.4E-60 T 11-10-2018 IPR000641 CbxX/CfqX GO:0005524 AFK25_06805 bf2a8c246c56e272413cb2cc18473c68 309 PRINTS PR00819 CbxX/CfqX superfamily signature 126 140 8.4E-60 T 11-10-2018 IPR000641 CbxX/CfqX GO:0005524 AFK25_06805 bf2a8c246c56e272413cb2cc18473c68 309 PRINTS PR00819 CbxX/CfqX superfamily signature 88 103 8.4E-60 T 11-10-2018 IPR000641 CbxX/CfqX GO:0005524 AFK25_06805 bf2a8c246c56e272413cb2cc18473c68 309 PRINTS PR00819 CbxX/CfqX superfamily signature 140 159 8.4E-60 T 11-10-2018 IPR000641 CbxX/CfqX GO:0005524 AFK25_06805 bf2a8c246c56e272413cb2cc18473c68 309 PRINTS PR00819 CbxX/CfqX superfamily signature 191 208 8.4E-60 T 11-10-2018 IPR000641 CbxX/CfqX GO:0005524 AFK25_06805 bf2a8c246c56e272413cb2cc18473c68 309 PRINTS PR00819 CbxX/CfqX superfamily signature 170 182 8.4E-60 T 11-10-2018 IPR000641 CbxX/CfqX GO:0005524 AFK25_06805 bf2a8c246c56e272413cb2cc18473c68 309 SUPERFAMILY SSF52540 39 305 1.6E-41 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_06805 bf2a8c246c56e272413cb2cc18473c68 309 TIGRFAM TIGR02881 spore_V_K: stage V sporulation protein K 45 306 1.4E-132 T 11-10-2018 IPR014232 Sporulation stage V, protein K AFK25_01300 ccb4abe730fac9e64d490c46857c7220 240 ProSitePatterns PS01057 SAICAR synthetase signature 1. 86 100 - T 11-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFK25_01300 ccb4abe730fac9e64d490c46857c7220 240 Gene3D G3DSA:3.30.200.20 7 232 1.6E-96 T 11-10-2018 AFK25_01300 ccb4abe730fac9e64d490c46857c7220 240 SUPERFAMILY SSF56104 2 236 4.25E-82 T 11-10-2018 AFK25_01300 ccb4abe730fac9e64d490c46857c7220 240 ProSitePatterns PS01058 SAICAR synthetase signature 2. 173 181 - T 11-10-2018 IPR018236 SAICAR synthetase, conserved site GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFK25_01300 ccb4abe730fac9e64d490c46857c7220 240 Pfam PF01259 SAICAR synthetase 7 231 2.3E-65 T 11-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFK25_01300 ccb4abe730fac9e64d490c46857c7220 240 Gene3D G3DSA:3.30.470.20 85 221 1.6E-96 T 11-10-2018 AFK25_01300 ccb4abe730fac9e64d490c46857c7220 240 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 5 232 2.5E-78 T 11-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 AFK25_01300 ccb4abe730fac9e64d490c46857c7220 240 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 4 235 32.487 T 11-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFK25_09125 90a411ce3ecd67a7593fa66bd3cceddd 483 ProSitePatterns PS00690 DEAH-box subfamily ATP-dependent helicases signature. 131 140 - T 11-10-2018 IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site AFK25_09125 90a411ce3ecd67a7593fa66bd3cceddd 483 SUPERFAMILY SSF52540 57 338 1.35E-59 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_09125 90a411ce3ecd67a7593fa66bd3cceddd 483 Gene3D G3DSA:3.40.50.300 1 196 4.6E-70 T 11-10-2018 AFK25_09125 90a411ce3ecd67a7593fa66bd3cceddd 483 SMART SM00487 13 194 2.0E-27 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFK25_09125 90a411ce3ecd67a7593fa66bd3cceddd 483 SMART SM00490 242 322 3.2E-25 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_09125 90a411ce3ecd67a7593fa66bd3cceddd 483 Pfam PF00270 DEAD/DEAH box helicase 21 178 4.5E-20 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFK25_09125 90a411ce3ecd67a7593fa66bd3cceddd 483 Pfam PF16124 RecQ zinc-binding 389 447 8.6E-6 T 11-10-2018 IPR032284 ATP-dependent DNA helicase RecQ, zinc-binding domain AFK25_09125 90a411ce3ecd67a7593fa66bd3cceddd 483 Pfam PF00271 Helicase conserved C-terminal domain 218 321 1.2E-17 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_09125 90a411ce3ecd67a7593fa66bd3cceddd 483 TIGRFAM TIGR00614 recQ_fam: ATP-dependent DNA helicase, RecQ family 6 389 3.7E-107 T 11-10-2018 IPR004589 DNA helicase, ATP-dependent, RecQ type GO:0006310|GO:0008026 AFK25_06855 8c6f7bad6a823d8e32d48438f100584b 134 Pfam PF13411 MerR HTH family regulatory protein 13 79 6.1E-20 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_06855 8c6f7bad6a823d8e32d48438f100584b 134 ProSitePatterns PS00552 MerR-type HTH domain signature. 15 37 - T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_06855 8c6f7bad6a823d8e32d48438f100584b 134 SMART SM00422 12 80 1.2E-29 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_06855 8c6f7bad6a823d8e32d48438f100584b 134 SUPERFAMILY SSF46955 12 110 5.04E-21 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily AFK25_06855 8c6f7bad6a823d8e32d48438f100584b 134 Gene3D G3DSA:1.10.1660.10 1 82 8.5E-27 T 11-10-2018 AFK25_04680 2f6ec8fc43da17f29fc389cdd5ff85bf 383 Pfam PF00155 Aminotransferase class I and II 29 374 7.4E-66 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFK25_04680 2f6ec8fc43da17f29fc389cdd5ff85bf 383 Gene3D G3DSA:3.40.640.10 58 277 2.4E-126 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_04680 2f6ec8fc43da17f29fc389cdd5ff85bf 383 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 227 240 - T 11-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AFK25_04680 2f6ec8fc43da17f29fc389cdd5ff85bf 383 Gene3D G3DSA:3.90.1150.10 28 374 2.4E-126 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_04680 2f6ec8fc43da17f29fc389cdd5ff85bf 383 SUPERFAMILY SSF53383 2 379 5.92E-112 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_00205 c8db2eed67fd964e20a350e00357da9e 288 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 16 214 2.2E-31 T 11-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFK25_00205 c8db2eed67fd964e20a350e00357da9e 288 ProSitePatterns PS01296 RsmI AdoMet-dependent methyltransferase protein family signature. 93 104 - T 11-10-2018 IPR018063 SAM-dependent methyltransferase RsmI, conserved site GO:0008168 AFK25_00205 c8db2eed67fd964e20a350e00357da9e 288 PIRSF PIRSF005917 3 288 2.6E-107 T 11-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 AFK25_00205 c8db2eed67fd964e20a350e00357da9e 288 Gene3D G3DSA:3.30.950.10 123 238 6.7E-43 T 11-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFK25_00205 c8db2eed67fd964e20a350e00357da9e 288 TIGRFAM TIGR00096 TIGR00096: 16S rRNA (cytidine(1402)-2'-O)-methyltransferase 15 287 4.0E-86 T 11-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 AFK25_00205 c8db2eed67fd964e20a350e00357da9e 288 Hamap MF_01877 Ribosomal RNA small subunit methyltransferase I [rsmI]. 15 233 37.623 T 11-10-2018 IPR008189 rRNA small subunit methyltransferase I GO:0008168 AFK25_00205 c8db2eed67fd964e20a350e00357da9e 288 SUPERFAMILY SSF53790 13 231 3.93E-84 T 11-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFK25_00205 c8db2eed67fd964e20a350e00357da9e 288 Gene3D G3DSA:3.40.1010.10 1 122 6.3E-49 T 11-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFK25_13660 a2457da5ff500fcfd6b60e1cbbaa7044 446 PIRSF PIRSF002746 1 446 1.5E-175 T 11-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 AFK25_13660 a2457da5ff500fcfd6b60e1cbbaa7044 446 TIGRFAM TIGR00791 gntP: transporter, gluconate:H+ symporter (GntP) family 7 445 2.9E-155 T 11-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 AFK25_13660 a2457da5ff500fcfd6b60e1cbbaa7044 446 Pfam PF02447 GntP family permease 7 443 4.3E-166 T 11-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 AFK25_13560 ac8099c2ef1f49065bd3e3fd8396759d 448 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 3 448 8.9E-87 T 11-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFK25_13560 ac8099c2ef1f49065bd3e3fd8396759d 448 PIRSF PIRSF000726 1 448 1.5E-78 T 11-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFK25_13560 ac8099c2ef1f49065bd3e3fd8396759d 448 Pfam PF00696 Amino acid kinase family 2 276 4.1E-39 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AFK25_13560 ac8099c2ef1f49065bd3e3fd8396759d 448 SUPERFAMILY SSF55021 371 448 9.16E-22 T 11-10-2018 AFK25_13560 ac8099c2ef1f49065bd3e3fd8396759d 448 Gene3D G3DSA:3.30.2130.10 290 448 8.9E-55 T 11-10-2018 AFK25_13560 ac8099c2ef1f49065bd3e3fd8396759d 448 Gene3D G3DSA:3.40.1160.10 3 287 5.4E-75 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFK25_13560 ac8099c2ef1f49065bd3e3fd8396759d 448 Pfam PF13840 ACT domain 380 444 2.9E-9 T 11-10-2018 IPR027795 CASTOR, ACT domain AFK25_13560 ac8099c2ef1f49065bd3e3fd8396759d 448 ProSitePatterns PS00324 Aspartokinase signature. 3 11 - T 11-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFK25_13560 ac8099c2ef1f49065bd3e3fd8396759d 448 SUPERFAMILY SSF53633 1 288 2.75E-66 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFK25_13560 ac8099c2ef1f49065bd3e3fd8396759d 448 Gene3D G3DSA:1.20.120.1320 39 135 5.4E-75 T 11-10-2018 AFK25_13560 ac8099c2ef1f49065bd3e3fd8396759d 448 SUPERFAMILY SSF55021 296 359 6.54E-10 T 11-10-2018 AFK25_00270 79ff539e627b177ccaa71d087afee58b 458 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 394 427 6.5E-7 T 11-10-2018 IPR001451 Hexapeptide repeat AFK25_00270 79ff539e627b177ccaa71d087afee58b 458 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 284 314 3.7E-6 T 11-10-2018 IPR001451 Hexapeptide repeat AFK25_00270 79ff539e627b177ccaa71d087afee58b 458 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 317 351 2.7E-8 T 11-10-2018 IPR001451 Hexapeptide repeat AFK25_00270 79ff539e627b177ccaa71d087afee58b 458 Gene3D G3DSA:3.90.550.10 1 251 1.1E-82 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_00270 79ff539e627b177ccaa71d087afee58b 458 TIGRFAM TIGR01173 glmU: UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase 5 451 9.8E-191 T 11-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 AFK25_00270 79ff539e627b177ccaa71d087afee58b 458 Pfam PF00483 Nucleotidyl transferase 5 209 2.8E-24 T 11-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFK25_00270 79ff539e627b177ccaa71d087afee58b 458 SUPERFAMILY SSF51161 248 449 6.39E-51 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily AFK25_00270 79ff539e627b177ccaa71d087afee58b 458 Gene3D G3DSA:2.160.10.10 252 438 1.0E-53 T 11-10-2018 AFK25_00270 79ff539e627b177ccaa71d087afee58b 458 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 402 430 - T 11-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 AFK25_00270 79ff539e627b177ccaa71d087afee58b 458 Hamap MF_01631 Bifunctional protein GlmU [glmU]. 2 451 42.632 T 11-10-2018 IPR005882 Bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase GO:0000287|GO:0000902|GO:0003977|GO:0005737|GO:0009103|GO:0009252|GO:0019134 KEGG: 00520+2.3.1.157+2.7.7.23|MetaCyc: PWY-5514 AFK25_00270 79ff539e627b177ccaa71d087afee58b 458 SUPERFAMILY SSF53448 3 306 3.38E-69 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_10145 f22f9df4987db9d97cc21fe8924f4807 269 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 23 269 1.9E-128 T 11-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 AFK25_10145 f22f9df4987db9d97cc21fe8924f4807 269 SMART SM00382 47 256 3.0E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_10145 f22f9df4987db9d97cc21fe8924f4807 269 Gene3D G3DSA:3.40.50.300 23 265 6.8E-65 T 11-10-2018 AFK25_10145 f22f9df4987db9d97cc21fe8924f4807 269 Pfam PF00005 ABC transporter 38 194 2.2E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_10145 f22f9df4987db9d97cc21fe8924f4807 269 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_10145 f22f9df4987db9d97cc21fe8924f4807 269 SUPERFAMILY SSF52540 16 256 6.9E-62 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_02620 6ade3e1bff87670b0224481d30518e3f 579 SUPERFAMILY SSF53738 28 235 2.94E-47 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_02620 6ade3e1bff87670b0224481d30518e3f 579 Gene3D G3DSA:3.40.120.10 33 190 4.8E-47 T 11-10-2018 AFK25_02620 6ade3e1bff87670b0224481d30518e3f 579 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 139 148 - T 11-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_02620 6ade3e1bff87670b0224481d30518e3f 579 Gene3D G3DSA:3.40.120.10 324 451 6.6E-35 T 11-10-2018 AFK25_02620 6ade3e1bff87670b0224481d30518e3f 579 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 228 247 3.7E-7 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_02620 6ade3e1bff87670b0224481d30518e3f 579 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 295 310 3.7E-7 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_02620 6ade3e1bff87670b0224481d30518e3f 579 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 138 152 3.7E-7 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_02620 6ade3e1bff87670b0224481d30518e3f 579 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 499 554 4.1E-9 T 11-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_02620 6ade3e1bff87670b0224481d30518e3f 579 Gene3D G3DSA:3.40.120.10 208 323 1.3E-24 T 11-10-2018 AFK25_02620 6ade3e1bff87670b0224481d30518e3f 579 SUPERFAMILY SSF53738 303 453 1.33E-31 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_02620 6ade3e1bff87670b0224481d30518e3f 579 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 208 314 2.2E-25 T 11-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_02620 6ade3e1bff87670b0224481d30518e3f 579 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 324 450 9.5E-23 T 11-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_02620 6ade3e1bff87670b0224481d30518e3f 579 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 41 181 1.2E-40 T 11-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_02620 6ade3e1bff87670b0224481d30518e3f 579 SUPERFAMILY SSF53738 211 311 5.06E-15 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_02620 6ade3e1bff87670b0224481d30518e3f 579 SUPERFAMILY SSF55957 445 570 4.19E-15 T 11-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_02620 6ade3e1bff87670b0224481d30518e3f 579 Gene3D G3DSA:3.30.310.50 489 568 4.3E-9 T 11-10-2018 AFK25_12580 9be7fe17285062503c27ed127cbe97db 284 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 67 81 - T 11-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFK25_12580 9be7fe17285062503c27ed127cbe97db 284 Gene3D G3DSA:3.10.310.10 6 280 1.8E-110 T 11-10-2018 AFK25_12580 9be7fe17285062503c27ed127cbe97db 284 Gene3D G3DSA:3.10.310.10 126 274 1.8E-110 T 11-10-2018 AFK25_12580 9be7fe17285062503c27ed127cbe97db 284 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 4 284 38.01 T 11-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFK25_12580 9be7fe17285062503c27ed127cbe97db 284 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 5 283 2.3E-94 T 11-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFK25_12580 9be7fe17285062503c27ed127cbe97db 284 SUPERFAMILY SSF54506 2 280 1.46E-49 T 11-10-2018 AFK25_12580 9be7fe17285062503c27ed127cbe97db 284 Pfam PF01678 Diaminopimelate epimerase 6 130 4.7E-32 T 11-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFK25_12580 9be7fe17285062503c27ed127cbe97db 284 Pfam PF01678 Diaminopimelate epimerase 162 275 2.3E-32 T 11-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AFK25_01960 ecb68f8acf600e977264647d3799adc1 1489 Pfam PF04898 Glutamate synthase central domain 446 725 3.8E-69 T 11-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 AFK25_01960 ecb68f8acf600e977264647d3799adc1 1489 Pfam PF00310 Glutamine amidotransferases class-II 21 385 1.7E-47 T 11-10-2018 IPR017932 Glutamine amidotransferase type 2 domain AFK25_01960 ecb68f8acf600e977264647d3799adc1 1489 Pfam PF01645 Conserved region in glutamate synthase 784 1147 7.3E-108 T 11-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 AFK25_01960 ecb68f8acf600e977264647d3799adc1 1489 SUPERFAMILY SSF56235 21 396 3.57E-75 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFK25_01960 ecb68f8acf600e977264647d3799adc1 1489 Gene3D G3DSA:2.160.20.60 1203 1489 8.9E-61 T 11-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 AFK25_01960 ecb68f8acf600e977264647d3799adc1 1489 Gene3D G3DSA:3.20.20.70 421 772 0.0 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_01960 ecb68f8acf600e977264647d3799adc1 1489 SUPERFAMILY SSF51395 445 1163 4.03E-164 T 11-10-2018 AFK25_01960 ecb68f8acf600e977264647d3799adc1 1489 Gene3D G3DSA:3.20.20.70 470 1163 0.0 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_01960 ecb68f8acf600e977264647d3799adc1 1489 Pfam PF01493 GXGXG motif 1249 1407 1.6E-16 T 11-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 AFK25_01960 ecb68f8acf600e977264647d3799adc1 1489 Gene3D G3DSA:3.60.20.10 21 531 0.0 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFK25_01960 ecb68f8acf600e977264647d3799adc1 1489 SUPERFAMILY SSF69336 1208 1486 1.44E-42 T 11-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 AFK25_11710 4ad8a751c4674f0ba1863b4f930cbd8b 150 Gene3D G3DSA:3.40.50.620 6 143 9.7E-43 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_11710 4ad8a751c4674f0ba1863b4f930cbd8b 150 Pfam PF00582 Universal stress protein family 4 143 2.3E-35 T 11-10-2018 IPR006016 UspA AFK25_11710 4ad8a751c4674f0ba1863b4f930cbd8b 150 SUPERFAMILY SSF52402 4 143 2.34E-36 T 11-10-2018 AFK25_11710 4ad8a751c4674f0ba1863b4f930cbd8b 150 PRINTS PR01438 Universal stress protein signature 121 143 5.0E-19 T 11-10-2018 IPR006015 Universal stress protein A AFK25_11710 4ad8a751c4674f0ba1863b4f930cbd8b 150 PRINTS PR01438 Universal stress protein signature 4 22 5.0E-19 T 11-10-2018 IPR006015 Universal stress protein A AFK25_11710 4ad8a751c4674f0ba1863b4f930cbd8b 150 PRINTS PR01438 Universal stress protein signature 103 115 5.0E-19 T 11-10-2018 IPR006015 Universal stress protein A AFK25_11710 4ad8a751c4674f0ba1863b4f930cbd8b 150 PIRSF PIRSF006276 1 146 7.8E-21 T 11-10-2018 IPR006015 Universal stress protein A AFK25_09330 544dfa33184dc3c1677b51e0416da276 114 SUPERFAMILY SSF55729 7 94 9.29E-14 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFK25_09330 544dfa33184dc3c1677b51e0416da276 114 Gene3D G3DSA:3.40.630.30 5 108 1.9E-14 T 11-10-2018 AFK25_09330 544dfa33184dc3c1677b51e0416da276 114 Pfam PF00583 Acetyltransferase (GNAT) family 35 95 6.7E-9 T 11-10-2018 IPR000182 GNAT domain AFK25_08300 9126d2906481037b5e1329b3dbcb0b97 437 Gene3D G3DSA:3.40.640.10 56 322 7.6E-173 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_08300 9126d2906481037b5e1329b3dbcb0b97 437 SUPERFAMILY SSF53383 13 426 2.02E-142 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_08300 9126d2906481037b5e1329b3dbcb0b97 437 Gene3D G3DSA:3.90.1150.10 4 420 7.6E-173 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_08300 9126d2906481037b5e1329b3dbcb0b97 437 Pfam PF00202 Aminotransferase class-III 18 423 4.1E-137 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFK25_08300 9126d2906481037b5e1329b3dbcb0b97 437 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 239 276 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFK25_08300 9126d2906481037b5e1329b3dbcb0b97 437 TIGRFAM TIGR00700 GABAtrnsam: 4-aminobutyrate transaminase 7 425 3.0E-187 T 11-10-2018 IPR004632 4-aminobutyrate aminotransferase, bacterial GO:0003867|GO:0009448 AFK25_08300 9126d2906481037b5e1329b3dbcb0b97 437 PIRSF PIRSF000521 24 126 9.2E-5 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFK25_08300 9126d2906481037b5e1329b3dbcb0b97 437 PIRSF PIRSF000521 120 427 1.4E-46 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFK25_03235 d7e0a35e3ace76c951bc93f29c895c48 259 SUPERFAMILY SSF52540 2 221 2.25E-56 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_03235 d7e0a35e3ace76c951bc93f29c895c48 259 Pfam PF00005 ABC transporter 18 158 7.5E-29 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_03235 d7e0a35e3ace76c951bc93f29c895c48 259 Gene3D G3DSA:3.40.50.300 1 257 6.2E-62 T 11-10-2018 AFK25_03235 d7e0a35e3ace76c951bc93f29c895c48 259 SMART SM00382 27 206 3.0E-6 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_00680 f387bb2d67b4a6f388694c9a4f881502 179 ProSitePatterns PS00525 Ribosomal protein L6 signature 1. 154 162 - T 11-10-2018 IPR002358 Ribosomal protein L6, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00680 f387bb2d67b4a6f388694c9a4f881502 179 SUPERFAMILY SSF56053 83 177 2.07E-35 T 11-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00680 f387bb2d67b4a6f388694c9a4f881502 179 Gene3D G3DSA:3.90.930.12 2 82 2.8E-35 T 11-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00680 f387bb2d67b4a6f388694c9a4f881502 179 PRINTS PR00059 Ribosomal protein L6 signature 99 115 4.5E-35 T 11-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFK25_00680 f387bb2d67b4a6f388694c9a4f881502 179 PRINTS PR00059 Ribosomal protein L6 signature 141 162 4.5E-35 T 11-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFK25_00680 f387bb2d67b4a6f388694c9a4f881502 179 PRINTS PR00059 Ribosomal protein L6 signature 71 96 4.5E-35 T 11-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFK25_00680 f387bb2d67b4a6f388694c9a4f881502 179 SUPERFAMILY SSF56053 1 82 2.3E-30 T 11-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00680 f387bb2d67b4a6f388694c9a4f881502 179 Gene3D G3DSA:3.90.930.12 83 178 2.2E-41 T 11-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00680 f387bb2d67b4a6f388694c9a4f881502 179 PIRSF PIRSF002162 1 177 1.9E-50 T 11-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00680 f387bb2d67b4a6f388694c9a4f881502 179 Hamap MF_01365_B 50S ribosomal protein L6 [rplF]. 1 176 40.31 T 11-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFK25_00680 f387bb2d67b4a6f388694c9a4f881502 179 TIGRFAM TIGR03654 L6_bact: ribosomal protein uL6 2 176 5.9E-79 T 11-10-2018 IPR019906 Ribosomal protein L6, bacterial-type GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFK25_00680 f387bb2d67b4a6f388694c9a4f881502 179 Pfam PF00347 Ribosomal protein L6 11 82 1.2E-25 T 11-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00680 f387bb2d67b4a6f388694c9a4f881502 179 Pfam PF00347 Ribosomal protein L6 90 164 9.5E-22 T 11-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 SUPERFAMILY SSF55008 2 65 6.68E-12 T 11-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 254 279 5.2E-72 T 11-10-2018 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 342 356 5.2E-72 T 11-10-2018 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 486 501 5.2E-72 T 11-10-2018 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 218 227 5.2E-72 T 11-10-2018 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 421 442 5.2E-72 T 11-10-2018 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 121 136 5.2E-72 T 11-10-2018 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 385 392 5.2E-72 T 11-10-2018 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 508 528 5.2E-72 T 11-10-2018 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 89 111 5.2E-72 T 11-10-2018 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 Gene3D G3DSA:3.50.50.60 227 348 1.1E-112 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_03970 84d74cf32953c905596464c90d7648b6 549 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 370 392 1.7E-32 T 11-10-2018 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 341 357 1.7E-32 T 11-10-2018 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 215 233 1.7E-32 T 11-10-2018 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 272 1.7E-32 T 11-10-2018 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 90 109 1.7E-32 T 11-10-2018 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 Gene3D G3DSA:3.50.50.60 88 411 1.1E-112 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_03970 84d74cf32953c905596464c90d7648b6 549 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 88 537 1.7E-127 T 11-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 SUPERFAMILY SSF55424 421 547 3.61E-36 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 TIGRFAM TIGR02053 MerA: mercury(II) reductase 88 548 4.0E-202 T 11-10-2018 IPR021179 Mercury(II) reductase GO:0016152|GO:0016491|GO:0045340|GO:0050660|GO:0050661|GO:0050787|GO:0055114 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 88 405 1.7E-76 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 36 - T 11-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 425 532 5.1E-33 T 11-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 Gene3D G3DSA:3.30.390.30 424 549 6.3E-43 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 Pfam PF00403 Heavy-metal-associated domain 6 64 4.4E-8 T 11-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 122 132 - T 11-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 Gene3D G3DSA:3.30.70.100 3 70 8.0E-15 T 11-10-2018 AFK25_03970 84d74cf32953c905596464c90d7648b6 549 SUPERFAMILY SSF51905 85 445 1.37E-59 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_03970 84d74cf32953c905596464c90d7648b6 549 PIRSF PIRSF000350 1 549 1.4E-257 T 11-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 AFK25_01965 7892100f59381ee369c70f30b2c20806 431 Pfam PF00202 Aminotransferase class-III 35 400 4.6E-70 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFK25_01965 7892100f59381ee369c70f30b2c20806 431 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 273 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFK25_01965 7892100f59381ee369c70f30b2c20806 431 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 5 427 1.6E-172 T 11-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 AFK25_01965 7892100f59381ee369c70f30b2c20806 431 SUPERFAMILY SSF53383 2 427 3.52E-127 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_01965 7892100f59381ee369c70f30b2c20806 431 Gene3D G3DSA:3.90.1150.10 9 423 3.1E-170 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_01965 7892100f59381ee369c70f30b2c20806 431 Gene3D G3DSA:3.40.640.10 72 320 3.1E-170 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_01965 7892100f59381ee369c70f30b2c20806 431 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 428 95.766 T 11-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 AFK25_08895 48c80b139a2ae4aa9d68e2a250ae4225 253 SUPERFAMILY SSF51366 9 249 8.19E-74 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFK25_08895 48c80b139a2ae4aa9d68e2a250ae4225 253 ProSitePatterns PS00614 Indole-3-glycerol phosphate synthase signature. 43 61 - T 11-10-2018 IPR001468 Indole-3-glycerol phosphate synthase, conserved site GO:0004425|GO:0006568 KEGG: 00400+4.1.1.48 AFK25_08895 48c80b139a2ae4aa9d68e2a250ae4225 253 Hamap MF_00134_B Indole-3-glycerol phosphate synthase [trpC]. 1 249 31.009 T 11-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 AFK25_08895 48c80b139a2ae4aa9d68e2a250ae4225 253 Gene3D G3DSA:3.20.20.70 1 252 3.7E-86 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_08895 48c80b139a2ae4aa9d68e2a250ae4225 253 Pfam PF00218 Indole-3-glycerol phosphate synthase 2 247 1.9E-82 T 11-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 AFK25_02590 9218506a1a5184cf628c09a6603bb41f 445 Gene3D G3DSA:3.10.580.10 195 346 2.1E-52 T 11-10-2018 AFK25_02590 9218506a1a5184cf628c09a6603bb41f 445 SUPERFAMILY SSF54631 204 340 1.77E-31 T 11-10-2018 AFK25_02590 9218506a1a5184cf628c09a6603bb41f 445 Pfam PF00571 CBS domain 288 337 4.8E-5 T 11-10-2018 IPR000644 CBS domain AFK25_02590 9218506a1a5184cf628c09a6603bb41f 445 Pfam PF00571 CBS domain 217 270 1.1E-6 T 11-10-2018 IPR000644 CBS domain AFK25_02590 9218506a1a5184cf628c09a6603bb41f 445 Gene3D G3DSA:3.30.465.10 347 428 4.7E-18 T 11-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFK25_02590 9218506a1a5184cf628c09a6603bb41f 445 SUPERFAMILY SSF56176 351 432 5.45E-19 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFK25_02590 9218506a1a5184cf628c09a6603bb41f 445 Pfam PF03471 Transporter associated domain 354 429 1.8E-17 T 11-10-2018 IPR005170 Transporter-associated domain AFK25_02590 9218506a1a5184cf628c09a6603bb41f 445 SMART SM01091 353 430 1.7E-21 T 11-10-2018 IPR005170 Transporter-associated domain AFK25_02590 9218506a1a5184cf628c09a6603bb41f 445 Pfam PF01595 Domain of unknown function DUF21 8 201 2.4E-52 T 11-10-2018 IPR002550 CNNM, transmembrane domain AFK25_07775 468c24eacc3f88e3da937c373d84d210 217 Pfam PF02581 Thiamine monophosphate synthase 8 191 5.2E-58 T 11-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFK25_07775 468c24eacc3f88e3da937c373d84d210 217 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 7 204 2.0E-63 T 11-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFK25_07775 468c24eacc3f88e3da937c373d84d210 217 SUPERFAMILY SSF51391 4 207 2.22E-67 T 11-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFK25_07775 468c24eacc3f88e3da937c373d84d210 217 Gene3D G3DSA:3.20.20.70 1 214 1.0E-72 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_07775 468c24eacc3f88e3da937c373d84d210 217 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 6 209 27.11 T 11-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFK25_04650 fe0c1157d98f3b50f9ac34ed697578aa 670 SUPERFAMILY SSF51261 518 668 1.03E-55 T 11-10-2018 IPR011055 Duplicated hybrid motif AFK25_04650 fe0c1157d98f3b50f9ac34ed697578aa 670 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 524 644 4.2E-48 T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 AFK25_04650 fe0c1157d98f3b50f9ac34ed697578aa 670 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 402 485 1.2E-22 T 11-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 AFK25_04650 fe0c1157d98f3b50f9ac34ed697578aa 670 Gene3D G3DSA:3.30.1360.60 422 502 2.0E-28 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 AFK25_04650 fe0c1157d98f3b50f9ac34ed697578aa 670 Pfam PF02378 Phosphotransferase system, EIIC 12 342 6.3E-95 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 AFK25_04650 fe0c1157d98f3b50f9ac34ed697578aa 670 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 439 456 - T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 AFK25_04650 fe0c1157d98f3b50f9ac34ed697578aa 670 Gene3D G3DSA:2.70.70.10 511 670 1.9E-61 T 11-10-2018 IPR011055 Duplicated hybrid motif AFK25_04650 fe0c1157d98f3b50f9ac34ed697578aa 670 TIGRFAM TIGR02002 PTS-II-BC-glcB: PTS system, glucose-specific IIBC component 1 501 2.6E-258 T 11-10-2018 IPR011299 PTS system glucose-specific IIBC component GO:0005355|GO:0016021|GO:1904659 AFK25_04650 fe0c1157d98f3b50f9ac34ed697578aa 670 TIGRFAM TIGR00852 pts-Glc: PTS system, maltose and glucose-specific subfamily, IIC component 63 353 1.2E-87 T 11-10-2018 IPR004719 Phosphotransferase system, maltose/glucose-specific subfamily IIC component GO:0008982|GO:0009401|GO:0016021 AFK25_04650 fe0c1157d98f3b50f9ac34ed697578aa 670 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 586 598 - T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 AFK25_04650 fe0c1157d98f3b50f9ac34ed697578aa 670 Pfam PF00367 phosphotransferase system, EIIB 429 461 6.5E-14 T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 AFK25_04650 fe0c1157d98f3b50f9ac34ed697578aa 670 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 523 645 4.1E-53 T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 AFK25_04650 fe0c1157d98f3b50f9ac34ed697578aa 670 SUPERFAMILY SSF55604 427 499 3.53E-21 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 AFK25_03575 98275ecb0ba92e6cc373e95444ffce78 387 Pfam PF01098 Cell cycle protein 15 379 3.0E-93 T 11-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_03575 98275ecb0ba92e6cc373e95444ffce78 387 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 336 360 - T 11-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_05545 1a11b91b802d3f59abb55ac02b137675 446 SUPERFAMILY SSF47446 329 430 1.64E-38 T 11-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AFK25_05545 1a11b91b802d3f59abb55ac02b137675 446 SMART SM00962 101 297 4.9E-127 T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFK25_05545 1a11b91b802d3f59abb55ac02b137675 446 Gene3D G3DSA:3.40.50.300 91 286 8.6E-134 T 11-10-2018 AFK25_05545 1a11b91b802d3f59abb55ac02b137675 446 SUPERFAMILY SSF52540 43 355 3.72E-63 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_05545 1a11b91b802d3f59abb55ac02b137675 446 TIGRFAM TIGR00959 ffh: signal recognition particle protein 3 429 1.6E-195 T 11-10-2018 IPR004780 Signal recognition particle protein Ffh GO:0003924|GO:0005525|GO:0006614|GO:0048500 AFK25_05545 1a11b91b802d3f59abb55ac02b137675 446 Gene3D G3DSA:1.10.260.30 328 444 1.9E-45 T 11-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AFK25_05545 1a11b91b802d3f59abb55ac02b137675 446 Gene3D G3DSA:1.20.120.140 6 307 8.6E-134 T 11-10-2018 AFK25_05545 1a11b91b802d3f59abb55ac02b137675 446 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 270 283 - T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFK25_05545 1a11b91b802d3f59abb55ac02b137675 446 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 6 446 36.246 T 11-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 AFK25_05545 1a11b91b802d3f59abb55ac02b137675 446 Pfam PF02978 Signal peptide binding domain 329 427 3.6E-35 T 11-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AFK25_05545 1a11b91b802d3f59abb55ac02b137675 446 SMART SM00382 100 277 7.1E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_05545 1a11b91b802d3f59abb55ac02b137675 446 Pfam PF02881 SRP54-type protein, helical bundle domain 6 83 6.9E-23 T 11-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFK25_05545 1a11b91b802d3f59abb55ac02b137675 446 Pfam PF00448 SRP54-type protein, GTPase domain 101 297 1.5E-82 T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFK25_05545 1a11b91b802d3f59abb55ac02b137675 446 SMART SM00963 2 87 1.6E-34 T 11-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFK25_01095 a7f8268851d31f5c3af2068dab7aa74f 385 Gene3D G3DSA:3.20.20.10 15 227 7.0E-131 T 11-10-2018 IPR029066 PLP-binding barrel AFK25_01095 a7f8268851d31f5c3af2068dab7aa74f 385 Pfam PF01168 Alanine racemase, N-terminal domain 13 232 3.7E-64 T 11-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFK25_01095 a7f8268851d31f5c3af2068dab7aa74f 385 SUPERFAMILY SSF50621 242 382 2.23E-50 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFK25_01095 a7f8268851d31f5c3af2068dab7aa74f 385 SUPERFAMILY SSF51419 13 240 2.04E-62 T 11-10-2018 IPR029066 PLP-binding barrel AFK25_01095 a7f8268851d31f5c3af2068dab7aa74f 385 SMART SM01005 247 372 7.3E-69 T 11-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFK25_01095 a7f8268851d31f5c3af2068dab7aa74f 385 Hamap MF_01201 Alanine racemase. 6 372 35.31 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFK25_01095 a7f8268851d31f5c3af2068dab7aa74f 385 ProSitePatterns PS00395 Alanine racemase pyridoxal-phosphate attachment site. 37 47 - T 11-10-2018 IPR020622 Alanine racemase, pyridoxal-phosphate attachment site KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFK25_01095 a7f8268851d31f5c3af2068dab7aa74f 385 TIGRFAM TIGR00492 alr: alanine racemase 7 372 7.8E-124 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFK25_01095 a7f8268851d31f5c3af2068dab7aa74f 385 PRINTS PR00992 Alanine racemase signature 68 86 8.7E-69 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFK25_01095 a7f8268851d31f5c3af2068dab7aa74f 385 PRINTS PR00992 Alanine racemase signature 280 295 8.7E-69 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFK25_01095 a7f8268851d31f5c3af2068dab7aa74f 385 PRINTS PR00992 Alanine racemase signature 130 142 8.7E-69 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFK25_01095 a7f8268851d31f5c3af2068dab7aa74f 385 PRINTS PR00992 Alanine racemase signature 165 176 8.7E-69 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFK25_01095 a7f8268851d31f5c3af2068dab7aa74f 385 PRINTS PR00992 Alanine racemase signature 263 278 8.7E-69 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFK25_01095 a7f8268851d31f5c3af2068dab7aa74f 385 PRINTS PR00992 Alanine racemase signature 32 48 8.7E-69 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFK25_01095 a7f8268851d31f5c3af2068dab7aa74f 385 PRINTS PR00992 Alanine racemase signature 354 367 8.7E-69 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFK25_01095 a7f8268851d31f5c3af2068dab7aa74f 385 PRINTS PR00992 Alanine racemase signature 205 232 8.7E-69 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFK25_01095 a7f8268851d31f5c3af2068dab7aa74f 385 PRINTS PR00992 Alanine racemase signature 300 317 8.7E-69 T 11-10-2018 IPR000821 Alanine racemase GO:0006522|GO:0008784 KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFK25_01095 a7f8268851d31f5c3af2068dab7aa74f 385 Gene3D G3DSA:2.40.37.10 10 370 7.0E-131 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFK25_01095 a7f8268851d31f5c3af2068dab7aa74f 385 Pfam PF00842 Alanine racemase, C-terminal domain 248 370 1.3E-44 T 11-10-2018 IPR011079 Alanine racemase, C-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFK25_02510 b13b0a5a0de0686fc6bbc8dc1d48027b 139 TIGRFAM TIGR01593 holin_tox_secr: toxin secretion/phage lysis holin 18 136 1.0E-26 T 11-10-2018 IPR006480 Bacteriophage holin family AFK25_02510 b13b0a5a0de0686fc6bbc8dc1d48027b 139 Pfam PF05105 Bacteriophage holin family 19 129 2.7E-32 T 11-10-2018 IPR006480 Bacteriophage holin family AFK25_04225 1bc7dc9965b8546dcea887724b2b31a6 332 Gene3D G3DSA:3.90.550.10 3 219 2.6E-31 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_04225 1bc7dc9965b8546dcea887724b2b31a6 332 Pfam PF00535 Glycosyl transferase family 2 6 174 6.0E-29 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFK25_04225 1bc7dc9965b8546dcea887724b2b31a6 332 SUPERFAMILY SSF53448 4 259 1.03E-29 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_12290 687c24ddc943a6def571fccb3ed9cf7a 240 Gene3D G3DSA:1.20.120.910 1 121 8.0E-32 T 11-10-2018 AFK25_12290 687c24ddc943a6def571fccb3ed9cf7a 240 Pfam PF01258 Prokaryotic dksA/traR C4-type zinc finger 83 111 1.5E-10 T 11-10-2018 IPR000962 Zinc finger, DksA/TraR C4-type GO:0008270 AFK25_12290 687c24ddc943a6def571fccb3ed9cf7a 240 SUPERFAMILY SSF109635 2 84 1.83E-12 T 11-10-2018 IPR037187 DksA, N-terminal domain superfamily AFK25_12290 687c24ddc943a6def571fccb3ed9cf7a 240 TIGRFAM TIGR02890 bacill_yteA: regulatory protein, yteA family 2 157 4.2E-65 T 11-10-2018 IPR014240 Regulatory protein, YteA family AFK25_12290 687c24ddc943a6def571fccb3ed9cf7a 240 SUPERFAMILY SSF57716 85 112 1.85E-6 T 11-10-2018 AFK25_01610 bc8e3f6da2540e88cd01c632fe92971e 218 Pfam PF08241 Methyltransferase domain 51 145 2.8E-25 T 11-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFK25_01610 bc8e3f6da2540e88cd01c632fe92971e 218 Gene3D G3DSA:3.40.50.150 8 217 2.6E-43 T 11-10-2018 AFK25_01610 bc8e3f6da2540e88cd01c632fe92971e 218 SUPERFAMILY SSF53335 14 208 1.81E-42 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_00570 548936ad6799573a1bc3c53140ce2037 1199 TIGRFAM TIGR02386 rpoC_TIGR: DNA-directed RNA polymerase, beta' subunit 10 1181 0.0 T 11-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00570 548936ad6799573a1bc3c53140ce2037 1199 Pfam PF04998 RNA polymerase Rpb1, domain 5 990 1129 2.3E-16 T 11-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00570 548936ad6799573a1bc3c53140ce2037 1199 Pfam PF05000 RNA polymerase Rpb1, domain 4 692 759 1.9E-14 T 11-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00570 548936ad6799573a1bc3c53140ce2037 1199 Gene3D G3DSA:1.10.150.390 1130 1192 9.8E-29 T 11-10-2018 AFK25_00570 548936ad6799573a1bc3c53140ce2037 1199 SMART SM00663 224 503 9.8E-185 T 11-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00570 548936ad6799573a1bc3c53140ce2037 1199 Gene3D G3DSA:1.10.40.90 363 405 9.7E-24 T 11-10-2018 AFK25_00570 548936ad6799573a1bc3c53140ce2037 1199 Gene3D G3DSA:1.10.132.30 660 794 3.3E-60 T 11-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00570 548936ad6799573a1bc3c53140ce2037 1199 Pfam PF04997 RNA polymerase Rpb1, domain 1 6 331 3.7E-90 T 11-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00570 548936ad6799573a1bc3c53140ce2037 1199 Gene3D G3DSA:2.40.50.100 966 1029 4.7E-71 T 11-10-2018 AFK25_00570 548936ad6799573a1bc3c53140ce2037 1199 Gene3D G3DSA:1.10.274.100 479 659 2.2E-49 T 11-10-2018 AFK25_00570 548936ad6799573a1bc3c53140ce2037 1199 Pfam PF04998 RNA polymerase Rpb1, domain 5 770 996 3.0E-52 T 11-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00570 548936ad6799573a1bc3c53140ce2037 1199 SUPERFAMILY SSF64484 5 1183 0.0 T 11-10-2018 AFK25_00570 548936ad6799573a1bc3c53140ce2037 1199 Hamap MF_01322 DNA-directed RNA polymerase subunit beta' [rpoC]. 4 1193 18.91 T 11-10-2018 IPR012754 DNA-directed RNA polymerase, subunit beta-prime GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00570 548936ad6799573a1bc3c53140ce2037 1199 Pfam PF04983 RNA polymerase Rpb1, domain 3 478 663 9.0E-38 T 11-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00570 548936ad6799573a1bc3c53140ce2037 1199 Pfam PF00623 RNA polymerase Rpb1, domain 2 379 474 2.0E-29 T 11-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00570 548936ad6799573a1bc3c53140ce2037 1199 Pfam PF00623 RNA polymerase Rpb1, domain 2 333 384 2.7E-9 T 11-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00570 548936ad6799573a1bc3c53140ce2037 1199 Gene3D G3DSA:1.10.1790.20 950 1128 4.7E-71 T 11-10-2018 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 Gene3D G3DSA:3.30.2090.10 704 793 0.0 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 PRINTS PR00702 Acriflavin resistance protein family signature 535 552 5.3E-59 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 PRINTS PR00702 Acriflavin resistance protein family signature 328 351 5.3E-59 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 PRINTS PR00702 Acriflavin resistance protein family signature 436 459 5.3E-59 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 PRINTS PR00702 Acriflavin resistance protein family signature 38 56 5.3E-59 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 PRINTS PR00702 Acriflavin resistance protein family signature 10 34 5.3E-59 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 PRINTS PR00702 Acriflavin resistance protein family signature 355 376 5.3E-59 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 PRINTS PR00702 Acriflavin resistance protein family signature 461 484 5.3E-59 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 PRINTS PR00702 Acriflavin resistance protein family signature 607 621 5.3E-59 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 PRINTS PR00702 Acriflavin resistance protein family signature 383 407 5.3E-59 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 Gene3D G3DSA:1.20.1640.10 10 498 0.0 T 11-10-2018 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 SUPERFAMILY SSF82866 794 1013 7.85E-50 T 11-10-2018 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 SUPERFAMILY SSF82693 134 320 1.52E-8 T 11-10-2018 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 Gene3D G3DSA:3.30.70.1440 656 851 0.0 T 11-10-2018 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 Gene3D G3DSA:1.20.1640.10 499 1006 0.0 T 11-10-2018 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 SUPERFAMILY SSF82866 288 489 5.1E-48 T 11-10-2018 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 Gene3D G3DSA:3.30.70.1320 132 324 0.0 T 11-10-2018 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 SUPERFAMILY SSF82714 179 261 2.62E-13 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 Gene3D G3DSA:3.30.70.1430 550 655 0.0 T 11-10-2018 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 Gene3D G3DSA:3.30.70.1430 40 801 0.0 T 11-10-2018 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 Gene3D G3DSA:3.30.2090.10 174 266 0.0 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 SUPERFAMILY SSF82693 549 634 1.18E-12 T 11-10-2018 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 SUPERFAMILY SSF82714 706 791 5.89E-15 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 SUPERFAMILY SSF82693 40 132 1.74E-21 T 11-10-2018 AFK25_13635 1882f0402920342ad4ae66e52bcaeb61 1018 Pfam PF00873 AcrB/AcrD/AcrF family 3 1007 6.8E-260 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFK25_00920 4766981c61c91b254dc4111b63a1a44f 482 Pfam PF03050 Transposase IS66 family 177 443 2.4E-60 T 11-10-2018 IPR004291 Transposase, IS66 AFK25_00920 4766981c61c91b254dc4111b63a1a44f 482 Pfam PF08961 Nuclear receptor-binding factor 2, autophagy regulator 16 56 5.2E-6 T 11-10-2018 IPR015056 Nuclear receptor-binding factor 2, C-terminal GO:0006914 Reactome: R-HSA-383280 AFK25_00920 4766981c61c91b254dc4111b63a1a44f 482 Pfam PF13005 zinc-finger binding domain of transposase IS66 117 161 4.6E-12 T 11-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 AFK25_03925 4766981c61c91b254dc4111b63a1a44f 482 Pfam PF03050 Transposase IS66 family 177 443 2.4E-60 T 11-10-2018 IPR004291 Transposase, IS66 AFK25_03925 4766981c61c91b254dc4111b63a1a44f 482 Pfam PF08961 Nuclear receptor-binding factor 2, autophagy regulator 16 56 5.2E-6 T 11-10-2018 IPR015056 Nuclear receptor-binding factor 2, C-terminal GO:0006914 Reactome: R-HSA-383280 AFK25_03925 4766981c61c91b254dc4111b63a1a44f 482 Pfam PF13005 zinc-finger binding domain of transposase IS66 117 161 4.6E-12 T 11-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 AFK25_02165 4766981c61c91b254dc4111b63a1a44f 482 Pfam PF03050 Transposase IS66 family 177 443 2.4E-60 T 11-10-2018 IPR004291 Transposase, IS66 AFK25_02165 4766981c61c91b254dc4111b63a1a44f 482 Pfam PF08961 Nuclear receptor-binding factor 2, autophagy regulator 16 56 5.2E-6 T 11-10-2018 IPR015056 Nuclear receptor-binding factor 2, C-terminal GO:0006914 Reactome: R-HSA-383280 AFK25_02165 4766981c61c91b254dc4111b63a1a44f 482 Pfam PF13005 zinc-finger binding domain of transposase IS66 117 161 4.6E-12 T 11-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 AFK25_06795 d708674f0262e5e905d8bb546c79ef44 311 SUPERFAMILY SSF52540 4 259 3.16E-12 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_06795 d708674f0262e5e905d8bb546c79ef44 311 Hamap MF_00185 tRNA dimethylallyltransferase [miaA]. 5 302 31.859 T 11-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 AFK25_06795 d708674f0262e5e905d8bb546c79ef44 311 Pfam PF01715 IPP transferase 38 278 4.3E-86 T 11-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 AFK25_06795 d708674f0262e5e905d8bb546c79ef44 311 Gene3D G3DSA:1.10.20.140 116 184 7.1E-111 T 11-10-2018 AFK25_06795 d708674f0262e5e905d8bb546c79ef44 311 TIGRFAM TIGR00174 miaA: tRNA dimethylallyltransferase 5 287 2.4E-116 T 11-10-2018 IPR018022 IPP transferase GO:0008033 KEGG: 00908+2.5.1.75|MetaCyc: PWY-2781|Reactome: R-HSA-6782315|Reactome: R-HSA-6787450 AFK25_06795 d708674f0262e5e905d8bb546c79ef44 311 Gene3D G3DSA:1.10.287.890 196 276 7.1E-111 T 11-10-2018 AFK25_06795 d708674f0262e5e905d8bb546c79ef44 311 SUPERFAMILY SSF52540 6 154 5.78E-20 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_06795 d708674f0262e5e905d8bb546c79ef44 311 Gene3D G3DSA:3.40.50.300 6 281 7.1E-111 T 11-10-2018 AFK25_05120 ab53689d5e3541fe2e6117d0e34586ff 188 Gene3D G3DSA:3.40.50.150 1 187 5.1E-58 T 11-10-2018 AFK25_05120 ab53689d5e3541fe2e6117d0e34586ff 188 PIRSF PIRSF004553 1 184 2.4E-50 T 11-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 AFK25_05120 ab53689d5e3541fe2e6117d0e34586ff 188 SUPERFAMILY SSF53335 1 180 6.46E-50 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_05120 ab53689d5e3541fe2e6117d0e34586ff 188 TIGRFAM TIGR00095 TIGR00095: 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD 2 180 2.3E-54 T 11-10-2018 IPR004398 RNA methyltransferase, RsmD GO:0008168|GO:0031167 AFK25_05120 ab53689d5e3541fe2e6117d0e34586ff 188 Pfam PF03602 Conserved hypothetical protein 95 1 180 3.6E-58 T 11-10-2018 AFK25_11120 2c5f890208880318e37e52f16616a2f3 444 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 156 7.0E-47 T 11-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFK25_11120 2c5f890208880318e37e52f16616a2f3 444 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 417 30.368 T 11-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFK25_11120 2c5f890208880318e37e52f16616a2f3 444 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 320 419 1.3E-22 T 11-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFK25_11120 2c5f890208880318e37e52f16616a2f3 444 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 171 306 1.0E-45 T 11-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase AFK25_11120 2c5f890208880318e37e52f16616a2f3 444 PIRSF PIRSF000445 1 434 2.5E-157 T 11-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFK25_11120 2c5f890208880318e37e52f16616a2f3 444 Gene3D G3DSA:3.40.50.720 161 313 9.0E-48 T 11-10-2018 AFK25_11120 2c5f890208880318e37e52f16616a2f3 444 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 420 3.3E-155 T 11-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFK25_11120 2c5f890208880318e37e52f16616a2f3 444 SUPERFAMILY SSF69742 1 158 1.57E-46 T 11-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFK25_11120 2c5f890208880318e37e52f16616a2f3 444 Gene3D G3DSA:3.30.460.30 2 158 3.7E-54 T 11-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFK25_11120 2c5f890208880318e37e52f16616a2f3 444 SUPERFAMILY SSF51735 162 315 1.05E-38 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_11120 2c5f890208880318e37e52f16616a2f3 444 SUPERFAMILY SSF69075 317 420 8.89E-18 T 11-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFK25_11120 2c5f890208880318e37e52f16616a2f3 444 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 99 122 - T 11-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AFK25_11020 47ba5b796252602286ba895fa375b9b6 344 Pfam PF00437 Type II/IV secretion system protein 79 270 7.7E-43 T 11-10-2018 IPR001482 Type II/IV secretion system protein AFK25_11020 47ba5b796252602286ba895fa375b9b6 344 Gene3D G3DSA:3.30.450.90 1 102 1.9E-34 T 11-10-2018 AFK25_11020 47ba5b796252602286ba895fa375b9b6 344 Gene3D G3DSA:3.40.50.300 103 343 1.6E-98 T 11-10-2018 AFK25_11020 47ba5b796252602286ba895fa375b9b6 344 SUPERFAMILY SSF52540 3 337 6.08E-70 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_11020 47ba5b796252602286ba895fa375b9b6 344 TIGRFAM TIGR01420 pilT_fam: twitching motility protein 5 336 6.7E-148 T 11-10-2018 IPR006321 Pilus retraction protein PilT GO:0005524 AFK25_11020 47ba5b796252602286ba895fa375b9b6 344 SMART SM00382 124 249 5.8E-6 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_11020 47ba5b796252602286ba895fa375b9b6 344 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 195 209 - T 11-10-2018 IPR001482 Type II/IV secretion system protein AFK25_12940 696102ce8b77b8cba7807c208be93be6 196 SUPERFAMILY SSF52096 10 194 2.18E-74 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFK25_12940 696102ce8b77b8cba7807c208be93be6 196 PRINTS PR00127 Clp protease catalytic subunit P signature 59 79 2.6E-54 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFK25_12940 696102ce8b77b8cba7807c208be93be6 196 PRINTS PR00127 Clp protease catalytic subunit P signature 90 107 2.6E-54 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFK25_12940 696102ce8b77b8cba7807c208be93be6 196 PRINTS PR00127 Clp protease catalytic subunit P signature 168 187 2.6E-54 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFK25_12940 696102ce8b77b8cba7807c208be93be6 196 PRINTS PR00127 Clp protease catalytic subunit P signature 111 130 2.6E-54 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFK25_12940 696102ce8b77b8cba7807c208be93be6 196 PRINTS PR00127 Clp protease catalytic subunit P signature 19 34 2.6E-54 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFK25_12940 696102ce8b77b8cba7807c208be93be6 196 TIGRFAM TIGR00493 clpP: ATP-dependent Clp endopeptidase, proteolytic subunit ClpP 1 192 8.6E-109 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFK25_12940 696102ce8b77b8cba7807c208be93be6 196 ProSitePatterns PS00381 Endopeptidase Clp serine active site. 90 101 - T 11-10-2018 IPR018215 ClpP, Ser active site AFK25_12940 696102ce8b77b8cba7807c208be93be6 196 Gene3D G3DSA:3.90.226.10 1 194 2.8E-84 T 11-10-2018 AFK25_12940 696102ce8b77b8cba7807c208be93be6 196 Pfam PF00574 Clp protease 12 192 1.5E-87 T 11-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA AFK25_12940 696102ce8b77b8cba7807c208be93be6 196 Hamap MF_00444 ATP-dependent Clp protease proteolytic subunit [clpP]. 3 193 44.715 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFK25_12940 696102ce8b77b8cba7807c208be93be6 196 ProSitePatterns PS00382 Endopeptidase Clp histidine active site. 112 125 - T 11-10-2018 IPR033135 ClpP, histidine active site AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 PRINTS PR00344 Bacterial sensor protein C-terminal signature 794 807 3.7E-18 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 PRINTS PR00344 Bacterial sensor protein C-terminal signature 735 749 3.7E-18 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 PRINTS PR00344 Bacterial sensor protein C-terminal signature 753 763 3.7E-18 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 PRINTS PR00344 Bacterial sensor protein C-terminal signature 770 788 3.7E-18 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 Gene3D G3DSA:1.10.287.130 577 656 6.9E-27 T 11-10-2018 AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 Gene3D G3DSA:3.30.565.10 657 813 1.2E-49 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 Gene3D G3DSA:1.20.1480.50 173 273 2.0E-11 T 11-10-2018 AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 SMART SM00065 320 460 0.0018 T 11-10-2018 IPR003018 GAF domain GO:0005515 AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 Gene3D G3DSA:3.30.450.40 293 458 6.8E-12 T 11-10-2018 IPR029016 GAF-like domain superfamily AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 Pfam PF00672 HAMP domain 214 265 6.8E-10 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 Pfam PF12860 PAS fold 470 586 1.7E-6 T 11-10-2018 AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 SMART SM00448 828 940 2.8E-25 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 SUPERFAMILY SSF158472 213 265 2.35E-7 T 11-10-2018 AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 Gene3D G3DSA:3.30.450.20 459 576 9.0E-12 T 11-10-2018 AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 698 808 3.4E-30 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 SUPERFAMILY SSF47384 575 655 1.2E-21 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 SUPERFAMILY SSF55781 302 473 2.18E-14 T 11-10-2018 AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 SUPERFAMILY SSF55874 643 808 2.75E-48 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 SUPERFAMILY SSF55785 455 580 1.58E-7 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 SMART SM00388 588 654 4.7E-24 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 SUPERFAMILY SSF52172 828 948 4.7E-27 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 Pfam PF00512 His Kinase A (phospho-acceptor) domain 588 654 4.7E-22 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 Gene3D G3DSA:3.40.50.12740 827 960 5.5E-31 T 11-10-2018 AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 Pfam PF00072 Response regulator receiver domain 830 940 3.9E-20 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 SMART SM00387 698 810 2.4E-44 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_04740 4f01c72be4dee34aab87263c7448b102 962 SMART SM00304 213 268 8.3E-9 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_04180 e15a30bbdec1ac9e60fd0bbe54243de6 336 Pfam PF00710 Asparaginase, N-terminal 3 187 3.2E-66 T 11-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 AFK25_04180 e15a30bbdec1ac9e60fd0bbe54243de6 336 Gene3D G3DSA:3.40.50.1170 1 199 2.4E-70 T 11-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 AFK25_04180 e15a30bbdec1ac9e60fd0bbe54243de6 336 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 1 327 7.4E-117 T 11-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 AFK25_04180 e15a30bbdec1ac9e60fd0bbe54243de6 336 PIRSF PIRSF500176 1 324 1.2E-101 T 11-10-2018 AFK25_04180 e15a30bbdec1ac9e60fd0bbe54243de6 336 Gene3D G3DSA:3.40.50.40 200 334 1.0E-37 T 11-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 AFK25_04180 e15a30bbdec1ac9e60fd0bbe54243de6 336 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 6 14 - T 11-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 AFK25_04180 e15a30bbdec1ac9e60fd0bbe54243de6 336 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 78 88 - T 11-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 AFK25_04180 e15a30bbdec1ac9e60fd0bbe54243de6 336 SUPERFAMILY SSF53774 1 329 1.18E-102 T 11-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 AFK25_04180 e15a30bbdec1ac9e60fd0bbe54243de6 336 PRINTS PR00139 Asparaginase/glutaminase family signature 252 270 1.1E-15 T 11-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AFK25_04180 e15a30bbdec1ac9e60fd0bbe54243de6 336 PRINTS PR00139 Asparaginase/glutaminase family signature 77 95 1.1E-15 T 11-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AFK25_04180 e15a30bbdec1ac9e60fd0bbe54243de6 336 PRINTS PR00139 Asparaginase/glutaminase family signature 4 15 1.1E-15 T 11-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AFK25_04180 e15a30bbdec1ac9e60fd0bbe54243de6 336 SMART SM00870 3 315 9.1E-124 T 11-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AFK25_04180 e15a30bbdec1ac9e60fd0bbe54243de6 336 PIRSF PIRSF001220 1 326 5.6E-94 T 11-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AFK25_00535 322cdf278ecb613bdac2afc73e8caf6f 177 Pfam PF00467 KOW motif 129 159 1.6E-5 T 11-10-2018 IPR005824 KOW AFK25_00535 322cdf278ecb613bdac2afc73e8caf6f 177 SUPERFAMILY SSF50104 121 177 5.26E-19 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily AFK25_00535 322cdf278ecb613bdac2afc73e8caf6f 177 Gene3D G3DSA:2.30.30.30 119 177 1.7E-24 T 11-10-2018 IPR014722 Ribosomal protein L2, domain 2 AFK25_00535 322cdf278ecb613bdac2afc73e8caf6f 177 Pfam PF02357 Transcription termination factor nusG 3 110 9.3E-30 T 11-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AFK25_00535 322cdf278ecb613bdac2afc73e8caf6f 177 SUPERFAMILY SSF82679 2 114 6.67E-42 T 11-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AFK25_00535 322cdf278ecb613bdac2afc73e8caf6f 177 SMART SM00739 123 150 6.0E-4 T 11-10-2018 IPR005824 KOW AFK25_00535 322cdf278ecb613bdac2afc73e8caf6f 177 Hamap MF_00948 Transcription termination/antitermination protein NusG [nusG]. 2 177 29.774 T 11-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 AFK25_00535 322cdf278ecb613bdac2afc73e8caf6f 177 ProSitePatterns PS01014 Transcription termination factor nusG signature. 160 169 - T 11-10-2018 IPR015869 Transcription antitermination protein, NusG, bacteria, conserved site AFK25_00535 322cdf278ecb613bdac2afc73e8caf6f 177 SMART SM00738 2 113 1.7E-55 T 11-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AFK25_00535 322cdf278ecb613bdac2afc73e8caf6f 177 Gene3D G3DSA:3.30.70.940 1 116 5.4E-47 T 11-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AFK25_00535 322cdf278ecb613bdac2afc73e8caf6f 177 PRINTS PR00338 Transcription termination factor NUSG signature 57 69 7.6E-21 T 11-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 AFK25_00535 322cdf278ecb613bdac2afc73e8caf6f 177 PRINTS PR00338 Transcription termination factor NUSG signature 153 169 7.6E-21 T 11-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 AFK25_00535 322cdf278ecb613bdac2afc73e8caf6f 177 PRINTS PR00338 Transcription termination factor NUSG signature 135 150 7.6E-21 T 11-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 AFK25_00535 322cdf278ecb613bdac2afc73e8caf6f 177 TIGRFAM TIGR00922 nusG: transcription termination/antitermination factor NusG 5 177 1.5E-65 T 11-10-2018 IPR001062 Transcription antitermination protein, NusG GO:0032784 AFK25_13010 97eb9a683a06249ddd9ce4205767233d 214 Gene3D G3DSA:3.40.190.10 93 174 6.5E-77 T 11-10-2018 AFK25_13010 97eb9a683a06249ddd9ce4205767233d 214 Gene3D G3DSA:3.40.190.10 4 196 6.5E-77 T 11-10-2018 AFK25_13010 97eb9a683a06249ddd9ce4205767233d 214 ProSitePatterns PS01316 ATP phosphoribosyltransferase signature. 141 162 - T 11-10-2018 IPR018198 ATP phosphoribosyltransferase, conserved site GO:0003879 KEGG: 00340+2.4.2.17 AFK25_13010 97eb9a683a06249ddd9ce4205767233d 214 Hamap MF_01018 ATP phosphoribosyltransferase [hisG]. 2 206 54.04 T 11-10-2018 IPR024893 ATP phosphoribosyltransferase HisG, short form GO:0000105|GO:0003879 KEGG: 00340+2.4.2.17 AFK25_13010 97eb9a683a06249ddd9ce4205767233d 214 Pfam PF01634 ATP phosphoribosyltransferase 52 201 9.7E-48 T 11-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 AFK25_13010 97eb9a683a06249ddd9ce4205767233d 214 SUPERFAMILY SSF53850 1 205 1.04E-63 T 11-10-2018 AFK25_13010 97eb9a683a06249ddd9ce4205767233d 214 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 3 182 2.1E-60 T 11-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 AFK25_04060 2c64e8b471e8d9e421a0a312964420a2 379 SUPERFAMILY SSF110836 2 90 4.58E-23 T 11-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily AFK25_04060 2c64e8b471e8d9e421a0a312964420a2 379 Gene3D G3DSA:3.30.1370.70 1 92 2.7E-27 T 11-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily AFK25_04060 2c64e8b471e8d9e421a0a312964420a2 379 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 3 89 1.3E-19 T 11-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal AFK25_04060 2c64e8b471e8d9e421a0a312964420a2 379 SUPERFAMILY SSF48371 202 372 3.62E-39 T 11-10-2018 IPR016024 Armadillo-type fold AFK25_04060 2c64e8b471e8d9e421a0a312964420a2 379 Pfam PF13646 HEAT repeats 270 343 1.5E-13 T 11-10-2018 AFK25_04060 2c64e8b471e8d9e421a0a312964420a2 379 SMART SM00567 E-Z type HEAT repeats 310 339 8.8E-5 T 11-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 AFK25_04060 2c64e8b471e8d9e421a0a312964420a2 379 SMART SM00567 E-Z type HEAT repeats 248 277 0.14 T 11-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 AFK25_04060 2c64e8b471e8d9e421a0a312964420a2 379 SMART SM00567 E-Z type HEAT repeats 218 246 38.0 T 11-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 AFK25_04060 2c64e8b471e8d9e421a0a312964420a2 379 SMART SM00567 E-Z type HEAT repeats 279 308 5.0E-4 T 11-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 AFK25_04060 2c64e8b471e8d9e421a0a312964420a2 379 Gene3D G3DSA:1.25.10.10 190 377 1.4E-32 T 11-10-2018 IPR011989 Armadillo-like helical AFK25_04060 2c64e8b471e8d9e421a0a312964420a2 379 Pfam PF13769 Virulence factor 109 189 5.9E-27 T 11-10-2018 IPR025989 Virulence factor domain AFK25_04060 2c64e8b471e8d9e421a0a312964420a2 379 SMART SM00932 3 90 1.5E-25 T 11-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal AFK25_07060 628f3a5e070cbf4af2d95e89972a94d2 183 SUPERFAMILY SSF46785 3 172 1.15E-34 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_07060 628f3a5e070cbf4af2d95e89972a94d2 183 Pfam PF10400 Virulence activator alpha C-term 103 171 1.7E-7 T 11-10-2018 IPR018309 Transcription regulator PadR, C-terminal AFK25_07060 628f3a5e070cbf4af2d95e89972a94d2 183 Pfam PF03551 Transcriptional regulator PadR-like family 7 82 1.0E-12 T 11-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFK25_07060 628f3a5e070cbf4af2d95e89972a94d2 183 Gene3D G3DSA:1.10.10.10 1 91 7.0E-23 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_09395 69383b8a0fd8864f2c175700c5059b45 139 Pfam PF13782 Stage V sporulation protein AB 26 134 5.1E-36 T 11-10-2018 IPR020144 Stage V sporulation protein AB AFK25_09395 69383b8a0fd8864f2c175700c5059b45 139 ProDom PD086170 SPORULATION AB V STAGE MEMBRANE SPOVAB TRANSMEMBRANE 26 137 9.0E-37 T 11-10-2018 IPR020144 Stage V sporulation protein AB AFK25_07220 7370a051c3d62e7563bcc975810fe348 798 Gene3D G3DSA:2.120.10.90 496 797 2.5E-92 T 11-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal AFK25_07220 7370a051c3d62e7563bcc975810fe348 798 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 547 595 2.4E-6 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFK25_07220 7370a051c3d62e7563bcc975810fe348 798 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 602 645 2.4E-9 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFK25_07220 7370a051c3d62e7563bcc975810fe348 798 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 700 735 0.12 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFK25_07220 7370a051c3d62e7563bcc975810fe348 798 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 652 691 8.4E-5 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFK25_07220 7370a051c3d62e7563bcc975810fe348 798 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 501 540 0.001 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFK25_07220 7370a051c3d62e7563bcc975810fe348 798 SUPERFAMILY SSF56719 27 482 6.93E-170 T 11-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFK25_07220 7370a051c3d62e7563bcc975810fe348 798 Gene3D G3DSA:3.30.1360.40 232 328 2.1E-199 T 11-10-2018 AFK25_07220 7370a051c3d62e7563bcc975810fe348 798 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 28 466 1.6E-150 T 11-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFK25_07220 7370a051c3d62e7563bcc975810fe348 798 SMART SM00434 7 460 2.0E-263 T 11-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFK25_07220 7370a051c3d62e7563bcc975810fe348 798 TIGRFAM TIGR01061 parC_Gpos: DNA topoisomerase IV, A subunit 5 739 0.0 T 11-10-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFK25_07220 7370a051c3d62e7563bcc975810fe348 798 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 11 790 3.2E-265 T 11-10-2018 AFK25_07220 7370a051c3d62e7563bcc975810fe348 798 SUPERFAMILY SSF101904 497 795 4.97E-85 T 11-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal AFK25_07220 7370a051c3d62e7563bcc975810fe348 798 Gene3D G3DSA:1.10.268.10 365 453 2.1E-199 T 11-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFK25_07220 7370a051c3d62e7563bcc975810fe348 798 Gene3D G3DSA:3.90.199.10 28 482 2.1E-199 T 11-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 AFK25_07220 7370a051c3d62e7563bcc975810fe348 798 Hamap MF_00937 DNA topoisomerase 4 subunit A [parC]. 3 796 32.72 T 11-10-2018 IPR005741 DNA topoisomerase IV subunit A, Gram-positive GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFK25_14255 c904109ed36e534ed7c8acd728fa6960 376 PIRSF PIRSF000183 1 371 2.9E-191 T 11-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 AFK25_14255 c904109ed36e534ed7c8acd728fa6960 376 SUPERFAMILY SSF51735 136 303 1.09E-47 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_14255 c904109ed36e534ed7c8acd728fa6960 376 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 140 352 3.7E-84 T 11-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain AFK25_14255 c904109ed36e534ed7c8acd728fa6960 376 Gene3D G3DSA:3.40.50.720 3 353 1.6E-143 T 11-10-2018 AFK25_14255 c904109ed36e534ed7c8acd728fa6960 376 Gene3D G3DSA:3.40.50.720 129 305 1.6E-143 T 11-10-2018 AFK25_14255 c904109ed36e534ed7c8acd728fa6960 376 SMART SM01002 148 297 3.3E-88 T 11-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain AFK25_14255 c904109ed36e534ed7c8acd728fa6960 376 SMART SM01003 4 136 6.0E-80 T 11-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal AFK25_14255 c904109ed36e534ed7c8acd728fa6960 376 Pfam PF05222 Alanine dehydrogenase/PNT, N-terminal domain 4 136 1.1E-48 T 11-10-2018 IPR007886 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal AFK25_14255 c904109ed36e534ed7c8acd728fa6960 376 ProSitePatterns PS00837 Alanine dehydrogenase & pyridine nucleotide transhydrogenase signature 2. 172 197 - T 11-10-2018 IPR008143 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 GO:0016491|GO:0055114 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1|Reactome: R-HSA-71403 AFK25_14255 c904109ed36e534ed7c8acd728fa6960 376 SUPERFAMILY SSF52283 1 360 1.79E-66 T 11-10-2018 AFK25_14255 c904109ed36e534ed7c8acd728fa6960 376 TIGRFAM TIGR00518 alaDH: alanine dehydrogenase 1 370 5.4E-187 T 11-10-2018 IPR008141 Alanine dehydrogenase GO:0000286|GO:0042853 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 AFK25_05610 bd3ba2704e029e266aaf3d9c24f160dd 300 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 288 44.129 T 11-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFK25_05610 bd3ba2704e029e266aaf3d9c24f160dd 300 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 236 249 - T 11-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site AFK25_05610 bd3ba2704e029e266aaf3d9c24f160dd 300 SMART SM00881 4 100 3.5E-38 T 11-10-2018 IPR003781 CoA-binding GO:0048037 AFK25_05610 bd3ba2704e029e266aaf3d9c24f160dd 300 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 4 288 8.0E-150 T 11-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFK25_05610 bd3ba2704e029e266aaf3d9c24f160dd 300 PIRSF PIRSF001553 1 291 2.7E-135 T 11-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFK25_05610 bd3ba2704e029e266aaf3d9c24f160dd 300 Gene3D G3DSA:3.40.50.720 1 123 9.9E-55 T 11-10-2018 AFK25_05610 bd3ba2704e029e266aaf3d9c24f160dd 300 SUPERFAMILY SSF51735 3 122 7.89E-47 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_05610 bd3ba2704e029e266aaf3d9c24f160dd 300 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 9.0E-42 T 11-10-2018 AFK25_05610 bd3ba2704e029e266aaf3d9c24f160dd 300 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 9.0E-42 T 11-10-2018 AFK25_05610 bd3ba2704e029e266aaf3d9c24f160dd 300 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 9.0E-42 T 11-10-2018 AFK25_05610 bd3ba2704e029e266aaf3d9c24f160dd 300 PRINTS PR01798 Succinyl-CoA synthase signature 240 257 9.0E-42 T 11-10-2018 AFK25_05610 bd3ba2704e029e266aaf3d9c24f160dd 300 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 11-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site AFK25_05610 bd3ba2704e029e266aaf3d9c24f160dd 300 SUPERFAMILY SSF52210 123 286 9.16E-54 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFK25_05610 bd3ba2704e029e266aaf3d9c24f160dd 300 Pfam PF00549 CoA-ligase 151 268 3.7E-18 T 11-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFK25_05610 bd3ba2704e029e266aaf3d9c24f160dd 300 Gene3D G3DSA:3.40.50.261 124 289 5.0E-71 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFK25_05610 bd3ba2704e029e266aaf3d9c24f160dd 300 Pfam PF02629 CoA binding domain 6 99 2.8E-34 T 11-10-2018 IPR003781 CoA-binding GO:0048037 AFK25_10390 05e4511f944f7158b4b23d96f0120bf8 344 Gene3D G3DSA:3.30.450.40 104 337 2.0E-58 T 11-10-2018 IPR029016 GAF-like domain superfamily AFK25_10390 05e4511f944f7158b4b23d96f0120bf8 344 Gene3D G3DSA:3.30.390.60 128 229 2.0E-58 T 11-10-2018 IPR023120 Winged helix-turn-helix transcription repressor, HrcA, inserted dimerising domain superfamily AFK25_10390 05e4511f944f7158b4b23d96f0120bf8 344 PIRSF PIRSF005485 1 341 1.7E-125 T 11-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 AFK25_10390 05e4511f944f7158b4b23d96f0120bf8 344 SUPERFAMILY SSF46785 2 84 6.75E-23 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_10390 05e4511f944f7158b4b23d96f0120bf8 344 TIGRFAM TIGR00331 hrcA: heat-inducible transcription repressor HrcA 3 336 1.3E-113 T 11-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 AFK25_10390 05e4511f944f7158b4b23d96f0120bf8 344 Gene3D G3DSA:1.10.10.10 1 83 6.1E-33 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_10390 05e4511f944f7158b4b23d96f0120bf8 344 SUPERFAMILY SSF55781 71 338 7.65E-70 T 11-10-2018 AFK25_10390 05e4511f944f7158b4b23d96f0120bf8 344 Hamap MF_00081 Heat-inducible transcription repressor HrcA [hrcA]. 1 330 33.784 T 11-10-2018 IPR002571 Heat-inducible transcription repressor HrcA GO:0003677|GO:0006355 AFK25_10390 05e4511f944f7158b4b23d96f0120bf8 344 Pfam PF01628 HrcA protein C terminal domain 104 323 4.9E-67 T 11-10-2018 IPR021153 Heat-inducible transcription repressor HrcA, C-terminal GO:0003677|GO:0006355 AFK25_00880 23927b310fa3a36657dab1319ca3161a 187 SUPERFAMILY SSF88946 6 98 6.28E-30 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_00880 23927b310fa3a36657dab1319ca3161a 187 Pfam PF08281 Sigma-70, region 4 128 180 3.3E-18 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFK25_00880 23927b310fa3a36657dab1319ca3161a 187 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 19 184 1.9E-38 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFK25_00880 23927b310fa3a36657dab1319ca3161a 187 Gene3D G3DSA:1.10.1740.10 5 108 1.8E-31 T 11-10-2018 AFK25_00880 23927b310fa3a36657dab1319ca3161a 187 SUPERFAMILY SSF88659 98 185 6.54E-20 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFK25_00880 23927b310fa3a36657dab1319ca3161a 187 TIGRFAM TIGR02948 SigW_bacill: RNA polymerase sigma-W factor 1 187 3.2E-104 T 11-10-2018 IPR014294 RNA polymerase sigma-W, bacillaceae AFK25_00880 23927b310fa3a36657dab1319ca3161a 187 Pfam PF04542 Sigma-70 region 2 24 89 1.2E-21 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_00880 23927b310fa3a36657dab1319ca3161a 187 Gene3D G3DSA:1.10.10.10 109 186 2.2E-23 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_11065 3ab2b6bf0f192945b66a6521b6265871 1137 Pfam PF02368 Bacterial Ig-like domain (group 2) 869 930 1.2E-5 T 11-10-2018 IPR003343 Bacterial Ig-like, group 2 AFK25_11065 3ab2b6bf0f192945b66a6521b6265871 1137 Pfam PF02368 Bacterial Ig-like domain (group 2) 951 1021 1.3E-15 T 11-10-2018 IPR003343 Bacterial Ig-like, group 2 AFK25_11065 3ab2b6bf0f192945b66a6521b6265871 1137 SUPERFAMILY SSF49373 948 1030 1.33E-17 T 11-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments AFK25_11065 3ab2b6bf0f192945b66a6521b6265871 1137 Pfam PF16480 Domain of unknown function (DUF5057) 112 399 1.7E-23 T 11-10-2018 IPR032480 Domain of unknown function DUF5057 AFK25_11065 3ab2b6bf0f192945b66a6521b6265871 1137 SUPERFAMILY SSF49373 1034 1114 2.43E-5 T 11-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments AFK25_11065 3ab2b6bf0f192945b66a6521b6265871 1137 Gene3D G3DSA:2.60.40.1080 865 949 4.4E-9 T 11-10-2018 AFK25_11065 3ab2b6bf0f192945b66a6521b6265871 1137 Gene3D G3DSA:2.60.40.1080 780 864 1.1E-8 T 11-10-2018 AFK25_11065 3ab2b6bf0f192945b66a6521b6265871 1137 Gene3D G3DSA:2.60.40.1080 950 1031 2.9E-21 T 11-10-2018 AFK25_11065 3ab2b6bf0f192945b66a6521b6265871 1137 SUPERFAMILY SSF49373 797 861 4.32E-6 T 11-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments AFK25_11065 3ab2b6bf0f192945b66a6521b6265871 1137 SMART SM00635 778 857 1.7 T 11-10-2018 IPR003343 Bacterial Ig-like, group 2 AFK25_11065 3ab2b6bf0f192945b66a6521b6265871 1137 SMART SM00635 866 943 1.4 T 11-10-2018 IPR003343 Bacterial Ig-like, group 2 AFK25_11065 3ab2b6bf0f192945b66a6521b6265871 1137 SMART SM00635 951 1028 6.2E-15 T 11-10-2018 IPR003343 Bacterial Ig-like, group 2 AFK25_11065 3ab2b6bf0f192945b66a6521b6265871 1137 SMART SM00635 1033 1113 0.39 T 11-10-2018 IPR003343 Bacterial Ig-like, group 2 AFK25_03220 efcffb6c03392c79ac215a37b30012e2 242 Gene3D G3DSA:1.10.1760.20 20 230 2.1E-49 T 11-10-2018 AFK25_03220 efcffb6c03392c79ac215a37b30012e2 242 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 20 226 4.8E-87 T 11-10-2018 IPR018024 Cobalamin (vitamin B12) transport protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 AFK25_03220 efcffb6c03392c79ac215a37b30012e2 242 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 21 227 2.8E-47 T 11-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 AFK25_03220 efcffb6c03392c79ac215a37b30012e2 242 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 20 235 28.129 T 11-10-2018 IPR018024 Cobalamin (vitamin B12) transport protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 AFK25_05345 d89beb8715727f31a3103a19f00c10db 427 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 15 423 3.8E-153 T 11-10-2018 AFK25_05345 d89beb8715727f31a3103a19f00c10db 427 ProSitePatterns PS00482 Dihydroorotase signature 1. 58 66 - T 11-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05345 d89beb8715727f31a3103a19f00c10db 427 ProSitePatterns PS00483 Dihydroorotase signature 2. 303 314 - T 11-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05345 d89beb8715727f31a3103a19f00c10db 427 Pfam PF01979 Amidohydrolase family 51 421 7.3E-60 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFK25_05345 d89beb8715727f31a3103a19f00c10db 427 SUPERFAMILY SSF51556 55 368 1.57E-114 T 11-10-2018 IPR032466 Metal-dependent hydrolase AFK25_05345 d89beb8715727f31a3103a19f00c10db 427 SUPERFAMILY SSF51338 2 426 8.78E-30 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFK25_05345 d89beb8715727f31a3103a19f00c10db 427 Hamap MF_00220_B Dihydroorotase [pyrC]. 3 424 45.234 T 11-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05345 d89beb8715727f31a3103a19f00c10db 427 Gene3D G3DSA:2.30.40.10 8 420 1.1E-159 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFK25_05345 d89beb8715727f31a3103a19f00c10db 427 Gene3D G3DSA:3.20.20.140 55 367 1.1E-159 T 11-10-2018 AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 Pfam PF14480 DNA polymerase III polC-type N-terminus I 9 80 6.8E-18 T 11-10-2018 IPR028112 DNA polymerase III polC-type, N-terminal domain I KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 Pfam PF00929 Exonuclease 416 570 4.9E-44 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 TIGRFAM TIGR01405 polC_Gram_pos: DNA polymerase III, alpha subunit, Gram-positive type 226 1430 0.0 T 11-10-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 Pfam PF02811 PHP domain 330 687 1.2E-54 T 11-10-2018 IPR004013 PHP domain GO:0003824 AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 818 1236 2.5E-99 T 11-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 Gene3D G3DSA:3.20.20.140 329 395 1.2E-11 T 11-10-2018 AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 Pfam PF11490 DNA polymerase III polC-type N-terminus II 95 199 2.7E-18 T 11-10-2018 IPR024754 DNA polymerase III polC-like, N-terminal domain II KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 Pfam PF14579 Helix-hairpin-helix motif 1345 1424 8.1E-10 T 11-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 Gene3D G3DSA:2.40.50.140 215 316 2.9E-34 T 11-10-2018 AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 Gene3D G3DSA:1.10.100.20 988 1035 2.6E-60 T 11-10-2018 AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 Hamap MF_00356 DNA polymerase III PolC-type [polC]. 1 1430 457.935 T 11-10-2018 IPR006308 DNA polymerase III, alpha subunit, Gram-positive type GO:0003677|GO:0003887|GO:0005737|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 SUPERFAMILY SSF53098 413 870 2.12E-113 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 SUPERFAMILY SSF160975 1369 1410 1.96E-5 T 11-10-2018 AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 Gene3D G3DSA:3.20.20.140 550 798 1.1E-52 T 11-10-2018 AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 Gene3D G3DSA:1.10.150.700 1226 1279 4.1E-15 T 11-10-2018 AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 Gene3D G3DSA:1.10.150.700 1089 1177 9.9E-37 T 11-10-2018 AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 Gene3D G3DSA:3.30.1900.20 966 1088 2.6E-60 T 11-10-2018 AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 Gene3D G3DSA:3.30.420.10 406 549 2.7E-47 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 SMART SM00481 329 396 5.0E-30 T 11-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 407 628 1.4E-64 T 11-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 SMART SM00479 414 580 1.9E-55 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 Gene3D G3DSA:1.10.150.870 1280 1416 1.4E-55 T 11-10-2018 AFK25_05865 4de89b34420efd09d92cb717dd8db297 1430 SUPERFAMILY SSF50249 231 315 8.74E-11 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_03345 bcb245dafe082b15379fcb2afa742eeb 268 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 235 1.1E-26 T 11-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 AFK25_03345 bcb245dafe082b15379fcb2afa742eeb 268 SUPERFAMILY SSF56784 1 266 8.7E-74 T 11-10-2018 IPR036412 HAD-like superfamily AFK25_03345 bcb245dafe082b15379fcb2afa742eeb 268 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 262 4.8E-72 T 11-10-2018 AFK25_03345 bcb245dafe082b15379fcb2afa742eeb 268 Gene3D G3DSA:3.30.1240.10 85 191 4.0E-69 T 11-10-2018 AFK25_03345 bcb245dafe082b15379fcb2afa742eeb 268 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 262 1.0E-61 T 11-10-2018 IPR000150 Cof family GO:0016787 AFK25_03345 bcb245dafe082b15379fcb2afa742eeb 268 Gene3D G3DSA:3.40.50.1000 6 261 4.0E-69 T 11-10-2018 IPR023214 HAD superfamily AFK25_05200 446ce7f0437e28baa35acdca0be2d00b 638 SUPERFAMILY SSF56519 49 218 1.1E-46 T 11-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 AFK25_05200 446ce7f0437e28baa35acdca0be2d00b 638 SUPERFAMILY SSF54184 582 635 8.11E-9 T 11-10-2018 AFK25_05200 446ce7f0437e28baa35acdca0be2d00b 638 SMART SM00740 578 636 1.0E-9 T 11-10-2018 IPR005543 PASTA domain AFK25_05200 446ce7f0437e28baa35acdca0be2d00b 638 Gene3D G3DSA:3.40.710.10 281 476 9.6E-113 T 11-10-2018 AFK25_05200 446ce7f0437e28baa35acdca0be2d00b 638 Gene3D G3DSA:3.30.450.330 220 559 9.6E-113 T 11-10-2018 AFK25_05200 446ce7f0437e28baa35acdca0be2d00b 638 Pfam PF03793 PASTA domain 582 635 4.2E-9 T 11-10-2018 IPR005543 PASTA domain AFK25_05200 446ce7f0437e28baa35acdca0be2d00b 638 Pfam PF03717 Penicillin-binding Protein dimerisation domain 54 199 3.7E-24 T 11-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 AFK25_05200 446ce7f0437e28baa35acdca0be2d00b 638 Gene3D G3DSA:3.30.10.20 579 635 2.2E-6 T 11-10-2018 AFK25_05200 446ce7f0437e28baa35acdca0be2d00b 638 Pfam PF00905 Penicillin binding protein transpeptidase domain 245 555 9.6E-86 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFK25_05200 446ce7f0437e28baa35acdca0be2d00b 638 Gene3D G3DSA:3.90.1310.30 47 218 4.3E-47 T 11-10-2018 AFK25_05200 446ce7f0437e28baa35acdca0be2d00b 638 TIGRFAM TIGR02214 spoVD_pbp: stage V sporulation protein D 9 635 6.0E-267 T 11-10-2018 IPR011927 Stage V sporulation protein D AFK25_05200 446ce7f0437e28baa35acdca0be2d00b 638 SUPERFAMILY SSF56601 169 566 5.81E-101 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFK25_03585 04a68fa329244e55eb3a233401c851e9 258 SUPERFAMILY SSF51735 6 255 1.9E-68 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_03585 04a68fa329244e55eb3a233401c851e9 258 Gene3D G3DSA:3.40.50.720 1 257 2.5E-60 T 11-10-2018 AFK25_03585 04a68fa329244e55eb3a233401c851e9 258 PIRSF PIRSF000094 2 258 1.1E-106 T 11-10-2018 IPR014358 Enoyl-[acyl-carrier-protein] reductase (NADH) GO:0004318|GO:0006633|GO:0055114 KEGG: 00061+1.3.1.9|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 AFK25_03585 04a68fa329244e55eb3a233401c851e9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.4E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_03585 04a68fa329244e55eb3a233401c851e9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 135 151 2.4E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_03585 04a68fa329244e55eb3a233401c851e9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 182 199 2.4E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_03585 04a68fa329244e55eb3a233401c851e9 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 161 180 2.4E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_03585 04a68fa329244e55eb3a233401c851e9 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 14 254 2.9E-88 T 11-10-2018 AFK25_14450 3ca79b792451bbd7427e41aaffae3907 496 Pfam PF00854 POT family 95 463 5.6E-75 T 11-10-2018 IPR000109 Proton-dependent oligopeptide transporter family GO:0016020|GO:0022857|GO:0055085 Reactome: R-HSA-427975 AFK25_14450 3ca79b792451bbd7427e41aaffae3907 496 Gene3D G3DSA:1.20.1250.20 2 496 1.7E-153 T 11-10-2018 AFK25_14450 3ca79b792451bbd7427e41aaffae3907 496 ProSitePatterns PS01023 PTR2 family proton/oligopeptide symporters signature 2. 157 169 - T 11-10-2018 IPR018456 PTR2 family proton/oligopeptide symporter, conserved site GO:0005215|GO:0006857|GO:0016020 Reactome: R-HSA-427975 AFK25_14450 3ca79b792451bbd7427e41aaffae3907 496 TIGRFAM TIGR00924 yjdL_sub1_fam: amino acid/peptide transporter (Peptide:H+ symporter) 16 492 4.7E-130 T 11-10-2018 IPR005279 Dipeptide/tripeptide permease GO:0015833|GO:0016020|GO:1904680 AFK25_14450 3ca79b792451bbd7427e41aaffae3907 496 SUPERFAMILY SSF103473 16 486 2.09E-29 T 11-10-2018 IPR036259 MFS transporter superfamily AFK25_04095 4c6c85ceb28607ce41232a7111a6c764 337 Gene3D G3DSA:3.40.50.300 1 232 3.7E-79 T 11-10-2018 AFK25_04095 4c6c85ceb28607ce41232a7111a6c764 337 SMART SM00930 258 333 8.4E-24 T 11-10-2018 IPR018449 NIL domain AFK25_04095 4c6c85ceb28607ce41232a7111a6c764 337 Pfam PF09383 NIL domain 260 332 7.1E-17 T 11-10-2018 IPR018449 NIL domain AFK25_04095 4c6c85ceb28607ce41232a7111a6c764 337 Pfam PF00005 ABC transporter 22 169 2.1E-37 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_04095 4c6c85ceb28607ce41232a7111a6c764 337 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_04095 4c6c85ceb28607ce41232a7111a6c764 337 SUPERFAMILY SSF55021 250 334 1.92E-19 T 11-10-2018 AFK25_04095 4c6c85ceb28607ce41232a7111a6c764 337 SUPERFAMILY SSF52540 1 240 1.04E-87 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_04095 4c6c85ceb28607ce41232a7111a6c764 337 SMART SM00382 30 224 1.5E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_04095 4c6c85ceb28607ce41232a7111a6c764 337 Gene3D G3DSA:3.30.70.260 233 335 2.1E-26 T 11-10-2018 AFK25_08785 f745aef3d7d9061bd5fe4a95cc9e8ccc 329 TIGRFAM TIGR00122 birA_repr_reg: biotin operon repressor 15 80 3.6E-22 T 11-10-2018 IPR004409 Biotin operon repressor, helix-turn-helix domain GO:0006355 KEGG: 00780+6.3.4.15 AFK25_08785 f745aef3d7d9061bd5fe4a95cc9e8ccc 329 SUPERFAMILY SSF46785 6 64 3.57E-10 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_08785 f745aef3d7d9061bd5fe4a95cc9e8ccc 329 SUPERFAMILY SSF50037 284 327 1.01E-5 T 11-10-2018 IPR008988 Transcriptional repressor, C-terminal AFK25_08785 f745aef3d7d9061bd5fe4a95cc9e8ccc 329 Pfam PF02237 Biotin protein ligase C terminal domain 280 325 7.5E-10 T 11-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFK25_08785 f745aef3d7d9061bd5fe4a95cc9e8ccc 329 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 92 325 3.1E-71 T 11-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFK25_08785 f745aef3d7d9061bd5fe4a95cc9e8ccc 329 Pfam PF08279 HTH domain 9 63 8.0E-16 T 11-10-2018 IPR013196 Helix-turn-helix, type 11 AFK25_08785 f745aef3d7d9061bd5fe4a95cc9e8ccc 329 Pfam PF03099 Biotin/lipoate A/B protein ligase family 94 217 5.5E-23 T 11-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 AFK25_08785 f745aef3d7d9061bd5fe4a95cc9e8ccc 329 Gene3D G3DSA:2.30.30.100 282 326 1.2E-7 T 11-10-2018 AFK25_08785 f745aef3d7d9061bd5fe4a95cc9e8ccc 329 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 11 327 37.876 T 11-10-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 AFK25_08785 f745aef3d7d9061bd5fe4a95cc9e8ccc 329 SUPERFAMILY SSF55681 75 277 1.99E-64 T 11-10-2018 AFK25_08785 f745aef3d7d9061bd5fe4a95cc9e8ccc 329 Gene3D G3DSA:3.30.930.10 76 278 9.5E-69 T 11-10-2018 AFK25_08785 f745aef3d7d9061bd5fe4a95cc9e8ccc 329 Gene3D G3DSA:1.10.10.10 4 68 4.8E-21 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 421 538 1.4E-41 T 11-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 SUPERFAMILY SSF56059 128 399 5.66E-112 T 11-10-2018 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 SUPERFAMILY SSF52335 934 1056 9.42E-35 T 11-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 Gene3D G3DSA:3.40.50.1380 929 1061 3.0E-39 T 11-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 Gene3D G3DSA:3.30.470.20 657 927 5.9E-108 T 11-10-2018 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 SUPERFAMILY SSF52440 1 127 3.17E-50 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 SUPERFAMILY SSF52440 549 666 3.6E-47 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 Gene3D G3DSA:3.40.50.20 545 653 2.3E-45 T 11-10-2018 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 828 835 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 700 714 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1044 0.0 T 11-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 SUPERFAMILY SSF56059 664 925 2.65E-103 T 11-10-2018 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1055 13.248 T 11-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 SUPERFAMILY SSF48108 395 544 2.88E-50 T 11-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 Gene3D G3DSA:3.30.470.20 120 401 2.3E-128 T 11-10-2018 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 SMART SM00851 947 1034 7.7E-31 T 11-10-2018 IPR011607 Methylglyoxal synthase-like domain AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 Pfam PF02142 MGS-like domain 948 1034 1.3E-22 T 11-10-2018 IPR011607 Methylglyoxal synthase-like domain AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 SMART SM01096 418 538 1.6E-68 T 11-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 665 865 2.0E-38 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 5.9E-82 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 8.3E-65 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 8.3E-65 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 8.3E-65 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 8.3E-65 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 8.3E-65 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 8.3E-65 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 8.3E-65 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1059 13.627 T 11-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 Gene3D G3DSA:1.10.1030.10 402 544 2.3E-46 T 11-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05355 defb141b9daeef5523f7fbdb5102cc66 1063 Gene3D G3DSA:3.40.50.20 1 116 6.4E-49 T 11-10-2018 AFK25_10565 6a7d719ee092fbed2b88f783dd64de5f 295 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 5 215 3.8E-48 T 11-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR AFK25_10565 6a7d719ee092fbed2b88f783dd64de5f 295 TIGRFAM TIGR02585 cas_Cst2_DevR: CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP 7 292 6.3E-63 T 11-10-2018 IPR013414 CRISPR-associated protein Cas7, subtype I-B/Tneap AFK25_10565 6a7d719ee092fbed2b88f783dd64de5f 295 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 6 209 7.9E-33 T 11-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR AFK25_12095 91cf278b97d05dd63f395d4e3198d2db 530 SUPERFAMILY SSF68923 13 212 8.55E-84 T 11-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 AFK25_12095 91cf278b97d05dd63f395d4e3198d2db 530 SUPERFAMILY SSF53795 214 521 3.2E-137 T 11-10-2018 AFK25_12095 91cf278b97d05dd63f395d4e3198d2db 530 Gene3D G3DSA:3.90.228.20 214 513 2.4E-231 T 11-10-2018 IPR013035 Phosphoenolpyruvate carboxykinase, C-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 AFK25_12095 91cf278b97d05dd63f395d4e3198d2db 530 PIRSF PIRSF006294 1 527 2.9E-248 T 11-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 AFK25_12095 91cf278b97d05dd63f395d4e3198d2db 530 TIGRFAM TIGR00224 pckA: phosphoenolpyruvate carboxykinase (ATP) 2 526 2.7E-252 T 11-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 AFK25_12095 91cf278b97d05dd63f395d4e3198d2db 530 Gene3D G3DSA:2.170.8.10 38 330 2.4E-231 T 11-10-2018 AFK25_12095 91cf278b97d05dd63f395d4e3198d2db 530 Hamap MF_00453 Phosphoenolpyruvate carboxykinase (ATP) [pckA]. 12 528 57.229 T 11-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 AFK25_12095 91cf278b97d05dd63f395d4e3198d2db 530 Gene3D G3DSA:3.40.449.10 28 213 2.4E-231 T 11-10-2018 IPR008210 Phosphoenolpyruvate carboxykinase, N-terminal GO:0004611|GO:0006094|GO:0017076 Reactome: R-HSA-70263 AFK25_12095 91cf278b97d05dd63f395d4e3198d2db 530 Pfam PF01293 Phosphoenolpyruvate carboxykinase 19 481 3.5E-231 T 11-10-2018 IPR001272 Phosphoenolpyruvate carboxykinase, ATP-utilising GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 AFK25_12095 91cf278b97d05dd63f395d4e3198d2db 530 ProSitePatterns PS00532 Phosphoenolpyruvate carboxykinase (ATP) signature. 250 265 - T 11-10-2018 IPR015994 Phosphoenolpyruvate carboxykinase (ATP), conserved site GO:0004612|GO:0005524|GO:0006094 KEGG: 00010+4.1.1.49|KEGG: 00020+4.1.1.49|KEGG: 00620+4.1.1.49|KEGG: 00710+4.1.1.49|MetaCyc: PWY-561|MetaCyc: PWY-7117 AFK25_00065 28bc9700c5349fd1904f9afa8552a639 233 Pfam PF14175 YaaC-like Protein 154 223 6.6E-24 T 11-10-2018 IPR026988 YaaC-like protein AFK25_00065 28bc9700c5349fd1904f9afa8552a639 233 Pfam PF14175 YaaC-like Protein 4 160 1.0E-61 T 11-10-2018 IPR026988 YaaC-like protein AFK25_06995 02ab29734537b8daec141a01c00eeedc 193 Pfam PF17248 Family of unknown function (DUF5317) 26 174 1.7E-50 T 11-10-2018 IPR035168 Protein of unknown function DUF5317 AFK25_02835 f511cd050684a28fa6ec85c692ddc271 30 TIGRFAM TIGR01732 tiny_TM_bacill: conserved hypothetical protein 4 29 2.7E-15 T 11-10-2018 IPR010070 Sporulation protein YjcZ-like AFK25_02835 f511cd050684a28fa6ec85c692ddc271 30 Pfam PF09680 Protein of unknown function (Tiny_TM_bacill) 6 28 6.6E-14 T 11-10-2018 IPR010070 Sporulation protein YjcZ-like AFK25_04785 b71429e503a041e36bfa3e88614b7a6b 110 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 3 107 2.6E-22 T 11-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 AFK25_04785 b71429e503a041e36bfa3e88614b7a6b 110 TIGRFAM TIGR00494 crcB: protein CrcB 3 110 7.5E-26 T 11-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 AFK25_04785 b71429e503a041e36bfa3e88614b7a6b 110 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 1 110 16.07 T 11-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 69 643 35.425 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 SUPERFAMILY SSF55681 245 534 3.38E-97 T 11-10-2018 AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 542 554 7.6E-48 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 366 389 7.6E-48 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 333 361 7.6E-48 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 472 500 7.6E-48 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 PRINTS PR01047 Threonyl-tRNA synthetase signature 515 528 7.6E-48 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 Gene3D G3DSA:3.30.980.10 72 224 1.4E-65 T 11-10-2018 AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 327 537 2.3E-33 T 11-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 Gene3D G3DSA:3.40.50.800 541 643 8.3E-34 T 11-10-2018 IPR036621 Anticodon-binding domain superfamily AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 75 640 1.1E-242 T 11-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 SMART SM00863 172 221 3.0E-26 T 11-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 SUPERFAMILY SSF52954 537 641 2.72E-32 T 11-10-2018 AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 SUPERFAMILY SSF81271 5 64 2.4E-15 T 11-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 SUPERFAMILY SSF55186 68 243 2.62E-66 T 11-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 Gene3D G3DSA:3.10.20.30 3 65 6.0E-25 T 11-10-2018 IPR012675 Beta-grasp domain superfamily AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 Gene3D G3DSA:3.30.54.20 133 189 1.4E-65 T 11-10-2018 AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 172 221 2.1E-17 T 11-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 Pfam PF03129 Anticodon binding domain 549 639 4.9E-25 T 11-10-2018 IPR004154 Anticodon-binding AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 Gene3D G3DSA:3.30.930.10 227 540 1.1E-118 T 11-10-2018 AFK25_11530 5f8c7a5f19e8a00ea8c2b17004bb3bfd 643 Pfam PF02824 TGS domain 5 64 3.8E-11 T 11-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 AFK25_06025 42f2cc671d4d3c128308a1bfe069e10b 485 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 152 177 - T 11-10-2018 IPR018212 Sodium/solute symporter, conserved site AFK25_06025 42f2cc671d4d3c128308a1bfe069e10b 485 TIGRFAM TIGR02121 Na_Pro_sym: sodium/proline symporter 3 481 2.9E-223 T 11-10-2018 IPR011851 Sodium/proline symporter GO:0005298|GO:0006814|GO:0015824|GO:0016021|GO:0031402 AFK25_06025 42f2cc671d4d3c128308a1bfe069e10b 485 Gene3D G3DSA:1.20.1730.10 18 484 2.0E-101 T 11-10-2018 IPR038377 Sodium/glucose symporter superfamily AFK25_06025 42f2cc671d4d3c128308a1bfe069e10b 485 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 30 428 1.1E-98 T 11-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AFK25_06025 42f2cc671d4d3c128308a1bfe069e10b 485 Pfam PF00474 Sodium:solute symporter family 30 428 1.7E-108 T 11-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AFK25_13375 995f009fd20a77f7bd44e715133092fd 731 ProSitePatterns PS00211 ABC transporters family signature. 622 636 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_13375 995f009fd20a77f7bd44e715133092fd 731 Gene3D G3DSA:3.40.50.300 469 722 4.8E-95 T 11-10-2018 AFK25_13375 995f009fd20a77f7bd44e715133092fd 731 Pfam PF00664 ABC transporter transmembrane region 170 436 4.7E-49 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFK25_13375 995f009fd20a77f7bd44e715133092fd 731 SMART SM00382 509 696 1.7E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_13375 995f009fd20a77f7bd44e715133092fd 731 SUPERFAMILY SSF90123 150 466 6.15E-69 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFK25_13375 995f009fd20a77f7bd44e715133092fd 731 SUPERFAMILY SSF52540 474 720 9.46E-91 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_13375 995f009fd20a77f7bd44e715133092fd 731 Pfam PF00005 ABC transporter 500 650 1.7E-38 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_13375 995f009fd20a77f7bd44e715133092fd 731 Pfam PF03412 Peptidase C39 family 8 140 4.6E-40 T 11-10-2018 IPR005074 Peptidase C39, bacteriocin processing GO:0005524|GO:0006508|GO:0008233|GO:0016021 AFK25_13375 995f009fd20a77f7bd44e715133092fd 731 TIGRFAM TIGR01193 bacteriocin_ABC: ABC-type bacteriocin transporter 13 718 3.2E-223 T 11-10-2018 IPR005897 Peptidase C39, ABC-type bacteriocin transporter GO:0008234|GO:0016020|GO:0022885|GO:0043213 AFK25_13375 995f009fd20a77f7bd44e715133092fd 731 Gene3D G3DSA:3.90.70.10 2 150 1.3E-53 T 11-10-2018 AFK25_13375 995f009fd20a77f7bd44e715133092fd 731 Gene3D G3DSA:1.20.1560.10 152 468 1.9E-94 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFK25_12255 bcd50cccc76eafb18b9688fcdd16b5d4 342 PIRSF PIRSF000267 1 342 1.0E-124 T 11-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 AFK25_12255 bcd50cccc76eafb18b9688fcdd16b5d4 342 TIGRFAM TIGR00203 cydB: cytochrome d ubiquinol oxidase, subunit II 3 213 4.6E-55 T 11-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 AFK25_12255 bcd50cccc76eafb18b9688fcdd16b5d4 342 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 7 329 5.0E-92 T 11-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 AFK25_13955 cae8f1769a5ce8f08cdbc25125223d25 320 Gene3D G3DSA:3.30.540.10 7 309 1.8E-136 T 11-10-2018 AFK25_13955 cae8f1769a5ce8f08cdbc25125223d25 320 SUPERFAMILY SSF56655 1 312 2.01E-113 T 11-10-2018 AFK25_13955 cae8f1769a5ce8f08cdbc25125223d25 320 PIRSF PIRSF004532 1 320 9.1E-152 T 11-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 AFK25_13955 cae8f1769a5ce8f08cdbc25125223d25 320 Gene3D G3DSA:3.40.190.90 122 283 1.8E-136 T 11-10-2018 AFK25_13955 cae8f1769a5ce8f08cdbc25125223d25 320 TIGRFAM TIGR00330 glpX: fructose-1,6-bisphosphatase, class II 1 320 7.0E-158 T 11-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 AFK25_13955 cae8f1769a5ce8f08cdbc25125223d25 320 Pfam PF03320 Bacterial fructose-1,6-bisphosphatase, glpX-encoded 3 309 1.2E-145 T 11-10-2018 IPR004464 Fructose-1,6-bisphosphatase class 2/Sedoheputulose-1,7-bisphosphatase GO:0006071|GO:0006094|GO:0042132 KEGG: 00010+3.1.3.11|KEGG: 00030+3.1.3.11|KEGG: 00051+3.1.3.11|KEGG: 00680+3.1.3.11|KEGG: 00710+3.1.3.11|MetaCyc: PWY-5484 AFK25_08185 017d3ae4e79f2755aef2e99967553a4a 277 Gene3D G3DSA:3.40.50.1010 6 274 6.4E-87 T 11-10-2018 AFK25_08185 017d3ae4e79f2755aef2e99967553a4a 277 Gene3D G3DSA:1.10.150.20 176 248 6.4E-87 T 11-10-2018 AFK25_08185 017d3ae4e79f2755aef2e99967553a4a 277 SUPERFAMILY SSF88723 4 155 2.11E-47 T 11-10-2018 IPR029060 PIN-like domain superfamily AFK25_08185 017d3ae4e79f2755aef2e99967553a4a 277 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 5 156 5.5E-49 T 11-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 AFK25_08185 017d3ae4e79f2755aef2e99967553a4a 277 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 173 264 2.4E-31 T 11-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 AFK25_08185 017d3ae4e79f2755aef2e99967553a4a 277 SMART SM00279 175 210 1.6E-16 T 11-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 AFK25_08185 017d3ae4e79f2755aef2e99967553a4a 277 SMART SM00475 2 263 4.5E-115 T 11-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 AFK25_08185 017d3ae4e79f2755aef2e99967553a4a 277 SUPERFAMILY SSF47807 173 264 8.52E-30 T 11-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily AFK25_14425 f7e33dca6188dcc01287e917314d5c26 364 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 196 361 8.5E-32 T 11-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 AFK25_14425 f7e33dca6188dcc01287e917314d5c26 364 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 2 363 1.0E-60 T 11-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 AFK25_14425 f7e33dca6188dcc01287e917314d5c26 364 Gene3D G3DSA:3.30.300.210 211 364 8.5E-23 T 11-10-2018 IPR038501 Spore germination GerAC superfamily AFK25_11260 946d5494adc3c9e89a8c20def2780fdc 593 SUPERFAMILY SSF46600 182 235 3.27E-14 T 11-10-2018 IPR036876 UVR domain superfamily AFK25_11260 946d5494adc3c9e89a8c20def2780fdc 593 SUPERFAMILY SSF47781 502 589 4.77E-21 T 11-10-2018 IPR010994 RuvA domain 2-like AFK25_11260 946d5494adc3c9e89a8c20def2780fdc 593 Gene3D G3DSA:3.40.1440.10 1 99 3.8E-38 T 11-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 AFK25_11260 946d5494adc3c9e89a8c20def2780fdc 593 Gene3D G3DSA:3.30.420.340 365 523 3.2E-62 T 11-10-2018 IPR038476 UvrC homology region 2 superfamily AFK25_11260 946d5494adc3c9e89a8c20def2780fdc 593 Hamap MF_00203 UvrABC system protein C [uvrC]. 2 587 28.658 T 11-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 AFK25_11260 946d5494adc3c9e89a8c20def2780fdc 593 Pfam PF12826 Helix-hairpin-helix motif 542 590 7.0E-7 T 11-10-2018 AFK25_11260 946d5494adc3c9e89a8c20def2780fdc 593 Gene3D G3DSA:1.10.150.20 527 589 3.1E-22 T 11-10-2018 AFK25_11260 946d5494adc3c9e89a8c20def2780fdc 593 Pfam PF01541 GIY-YIG catalytic domain 16 90 3.0E-9 T 11-10-2018 IPR000305 GIY-YIG endonuclease AFK25_11260 946d5494adc3c9e89a8c20def2780fdc 593 SUPERFAMILY SSF82771 14 97 2.88E-22 T 11-10-2018 IPR035901 GIY-YIG endonuclease superfamily Reactome: R-HSA-5693568|Reactome: R-HSA-6783310 AFK25_11260 946d5494adc3c9e89a8c20def2780fdc 593 Pfam PF08459 UvrC Helix-hairpin-helix N-terminal 371 523 4.3E-55 T 11-10-2018 IPR001162 UvrC family homology region AFK25_11260 946d5494adc3c9e89a8c20def2780fdc 593 Pfam PF02151 UvrB/uvrC motif 196 230 2.9E-8 T 11-10-2018 IPR001943 UVR domain GO:0005515 AFK25_11260 946d5494adc3c9e89a8c20def2780fdc 593 SMART SM00465 15 95 2.7E-23 T 11-10-2018 IPR000305 GIY-YIG endonuclease AFK25_11260 946d5494adc3c9e89a8c20def2780fdc 593 TIGRFAM TIGR00194 uvrC: excinuclease ABC subunit C 5 570 1.6E-215 T 11-10-2018 IPR004791 UvrABC system, subunit C GO:0006289|GO:0009380|GO:0009381 AFK25_09550 ef8dd5b0e7bf0c34d32ea9f956e0e2dd 333 TIGRFAM TIGR02666 moaA: molybdenum cofactor biosynthesis protein A 3 333 2.7E-117 T 11-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFK25_09550 ef8dd5b0e7bf0c34d32ea9f956e0e2dd 333 SMART SM00729 11 218 9.7E-11 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFK25_09550 ef8dd5b0e7bf0c34d32ea9f956e0e2dd 333 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 17 28 - T 11-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFK25_09550 ef8dd5b0e7bf0c34d32ea9f956e0e2dd 333 Gene3D G3DSA:3.20.20.70 1 333 3.1E-101 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_09550 ef8dd5b0e7bf0c34d32ea9f956e0e2dd 333 SUPERFAMILY SSF102114 3 312 2.35E-78 T 11-10-2018 AFK25_09550 ef8dd5b0e7bf0c34d32ea9f956e0e2dd 333 Hamap MF_01225_B GTP 3',8-cyclase [moaA]. 2 333 40.101 T 11-10-2018 IPR013483 Molybdenum cofactor biosynthesis protein A GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFK25_09550 ef8dd5b0e7bf0c34d32ea9f956e0e2dd 333 Pfam PF04055 Radical SAM superfamily 15 176 7.9E-28 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFK25_09550 ef8dd5b0e7bf0c34d32ea9f956e0e2dd 333 Pfam PF06463 Molybdenum Cofactor Synthesis C 186 312 1.4E-36 T 11-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFK25_09550 ef8dd5b0e7bf0c34d32ea9f956e0e2dd 333 Pfam PF13353 4Fe-4S single cluster domain 19 124 7.4E-9 T 11-10-2018 AFK25_14055 95665d6728880ce3a8c338e5a87ee149 275 Pfam PF01564 Spermine/spermidine synthase domain 58 236 1.0E-70 T 11-10-2018 AFK25_14055 95665d6728880ce3a8c338e5a87ee149 275 SUPERFAMILY SSF53335 3 274 1.76E-88 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_14055 95665d6728880ce3a8c338e5a87ee149 275 Pfam PF17284 Spermidine synthase tetramerisation domain 3 54 7.6E-20 T 11-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFK25_14055 95665d6728880ce3a8c338e5a87ee149 275 TIGRFAM TIGR00417 speE: spermidine synthase 4 269 7.3E-122 T 11-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFK25_14055 95665d6728880ce3a8c338e5a87ee149 275 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 79 92 - T 11-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFK25_14055 95665d6728880ce3a8c338e5a87ee149 275 Gene3D G3DSA:2.30.140.10 1 52 2.7E-25 T 11-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFK25_14055 95665d6728880ce3a8c338e5a87ee149 275 Gene3D G3DSA:3.40.50.150 53 274 6.8E-78 T 11-10-2018 AFK25_14055 95665d6728880ce3a8c338e5a87ee149 275 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 3 275 42.261 T 11-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFK25_13960 c8c288ee77c56dcd8a1984fd1fc38c2a 428 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1 414 4.3E-170 T 11-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFK25_13960 c8c288ee77c56dcd8a1984fd1fc38c2a 428 Gene3D G3DSA:3.65.10.10 21 228 8.0E-160 T 11-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AFK25_13960 c8c288ee77c56dcd8a1984fd1fc38c2a 428 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 10 405 1.7E-93 T 11-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 AFK25_13960 c8c288ee77c56dcd8a1984fd1fc38c2a 428 SUPERFAMILY SSF55205 1 414 1.96E-132 T 11-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 AFK25_13960 c8c288ee77c56dcd8a1984fd1fc38c2a 428 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 415 42.042 T 11-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFK25_13960 c8c288ee77c56dcd8a1984fd1fc38c2a 428 Gene3D G3DSA:3.65.10.10 6 412 8.0E-160 T 11-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AFK25_09490 c56374a52702ce66b3fa762700986159 491 Pfam PF13247 4Fe-4S dicluster domain 172 269 1.2E-36 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFK25_09490 c56374a52702ce66b3fa762700986159 491 Gene3D G3DSA:1.10.3650.10 356 434 1.6E-26 T 11-10-2018 IPR038262 Nitrate reductase beta, C-terminal domain superfamily KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 AFK25_09490 c56374a52702ce66b3fa762700986159 491 SUPERFAMILY SSF54862 2 488 8.48E-162 T 11-10-2018 AFK25_09490 c56374a52702ce66b3fa762700986159 491 TIGRFAM TIGR01660 narH: nitrate reductase, beta subunit 1 485 2.6E-269 T 11-10-2018 IPR006547 Nitrate reductase, beta subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 AFK25_09490 c56374a52702ce66b3fa762700986159 491 Gene3D G3DSA:3.30.70.20 1 304 7.5E-100 T 11-10-2018 AFK25_09490 c56374a52702ce66b3fa762700986159 491 Pfam PF14711 Respiratory nitrate reductase beta C-terminal 356 435 5.6E-28 T 11-10-2018 IPR029263 Respiratory nitrate reductase beta, C-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 AFK25_03005 f517c8301af8e0ab61294e4ae65aaab4 196 Pfam PF02630 SCO1/SenC 30 175 6.5E-20 T 11-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_03005 f517c8301af8e0ab61294e4ae65aaab4 196 Gene3D G3DSA:3.40.30.10 26 196 7.4E-42 T 11-10-2018 AFK25_03005 f517c8301af8e0ab61294e4ae65aaab4 196 SUPERFAMILY SSF52833 35 193 4.3E-34 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_10160 2d704855b2658a237411c4b3dba8546c 320 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 1 303 2.0E-89 T 11-10-2018 IPR011862 Phosphate binding protein GO:0042301 AFK25_10160 2d704855b2658a237411c4b3dba8546c 320 SUPERFAMILY SSF53850 39 317 2.79E-74 T 11-10-2018 AFK25_10160 2d704855b2658a237411c4b3dba8546c 320 Gene3D G3DSA:3.40.190.10 121 265 3.8E-90 T 11-10-2018 AFK25_10160 2d704855b2658a237411c4b3dba8546c 320 Pfam PF12849 PBP superfamily domain 34 290 3.5E-34 T 11-10-2018 IPR024370 PBP domain AFK25_10160 2d704855b2658a237411c4b3dba8546c 320 Gene3D G3DSA:3.40.190.10 42 302 3.8E-90 T 11-10-2018 AFK25_05940 b643e3a43994f2d9809845560654ff00 308 SMART SM00997 140 295 0.0097 T 11-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AFK25_05940 b643e3a43994f2d9809845560654ff00 308 Pfam PF16924 Dipicolinate synthase subunit A N-terminal domain 14 131 5.7E-31 T 11-10-2018 IPR031629 Dipicolinate synthase subunit A, N-terminal AFK25_05940 b643e3a43994f2d9809845560654ff00 308 Pfam PF01262 Alanine dehydrogenase/PNT, C-terminal domain 149 298 2.2E-10 T 11-10-2018 IPR007698 Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain AFK25_05940 b643e3a43994f2d9809845560654ff00 308 TIGRFAM TIGR02853 spore_dpaA: dipicolinic acid synthetase, A subunit 12 297 6.0E-140 T 11-10-2018 IPR014215 Dipicolinic acid synthetase subunit A AFK25_05940 b643e3a43994f2d9809845560654ff00 308 Gene3D G3DSA:3.40.50.720 134 280 6.6E-106 T 11-10-2018 AFK25_05940 b643e3a43994f2d9809845560654ff00 308 Gene3D G3DSA:3.40.50.720 15 296 6.6E-106 T 11-10-2018 AFK25_05940 b643e3a43994f2d9809845560654ff00 308 SUPERFAMILY SSF51735 139 277 3.14E-20 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_09570 c431b8ee228eee135a2b05ef9e6b4127 443 TIGRFAM TIGR00886 2A0108: nitrite transporter 40 394 1.9E-99 T 11-10-2018 IPR004737 Nitrate transporter GO:0015112|GO:0015113|GO:0015706|GO:0015707|GO:0016021 AFK25_09570 c431b8ee228eee135a2b05ef9e6b4127 443 Pfam PF07690 Major Facilitator Superfamily 51 399 2.1E-17 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFK25_09570 c431b8ee228eee135a2b05ef9e6b4127 443 SUPERFAMILY SSF103473 20 435 2.35E-46 T 11-10-2018 IPR036259 MFS transporter superfamily AFK25_09570 c431b8ee228eee135a2b05ef9e6b4127 443 Gene3D G3DSA:1.20.1250.20 6 241 9.7E-81 T 11-10-2018 AFK25_09570 c431b8ee228eee135a2b05ef9e6b4127 443 Gene3D G3DSA:1.20.1250.20 243 442 6.4E-65 T 11-10-2018 AFK25_05275 3f24f2c16450a7e9016da6bbc2d4129b 259 PIRSF PIRSF000770 16 258 1.5E-34 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05275 3f24f2c16450a7e9016da6bbc2d4129b 259 Pfam PF04545 Sigma-70, region 4 207 253 1.5E-13 T 11-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFK25_05275 3f24f2c16450a7e9016da6bbc2d4129b 259 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 37 257 2.3E-83 T 11-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFK25_05275 3f24f2c16450a7e9016da6bbc2d4129b 259 TIGRFAM TIGR02850 spore_sigG: RNA polymerase sigma-G factor 4 257 8.6E-157 T 11-10-2018 IPR014212 RNA polymerase sigma-G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFK25_05275 3f24f2c16450a7e9016da6bbc2d4129b 259 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 37 256 6.3E-36 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFK25_05275 3f24f2c16450a7e9016da6bbc2d4129b 259 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 66 79 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05275 3f24f2c16450a7e9016da6bbc2d4129b 259 SUPERFAMILY SSF88659 175 257 1.16E-16 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFK25_05275 3f24f2c16450a7e9016da6bbc2d4129b 259 PRINTS PR00046 Major sigma-70 factor signature 227 242 1.8E-12 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05275 3f24f2c16450a7e9016da6bbc2d4129b 259 PRINTS PR00046 Major sigma-70 factor signature 90 98 1.8E-12 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05275 3f24f2c16450a7e9016da6bbc2d4129b 259 PRINTS PR00046 Major sigma-70 factor signature 242 253 1.8E-12 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05275 3f24f2c16450a7e9016da6bbc2d4129b 259 PRINTS PR00046 Major sigma-70 factor signature 210 222 1.8E-12 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05275 3f24f2c16450a7e9016da6bbc2d4129b 259 PRINTS PR00046 Major sigma-70 factor signature 66 79 1.8E-12 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05275 3f24f2c16450a7e9016da6bbc2d4129b 259 Gene3D G3DSA:1.20.140.160 113 258 8.2E-25 T 11-10-2018 AFK25_05275 3f24f2c16450a7e9016da6bbc2d4129b 259 Pfam PF04539 Sigma-70 region 3 124 173 8.6E-7 T 11-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 AFK25_05275 3f24f2c16450a7e9016da6bbc2d4129b 259 Pfam PF04542 Sigma-70 region 2 42 110 2.2E-17 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_05275 3f24f2c16450a7e9016da6bbc2d4129b 259 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 227 253 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05275 3f24f2c16450a7e9016da6bbc2d4129b 259 SUPERFAMILY SSF88946 13 110 1.57E-34 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_05275 3f24f2c16450a7e9016da6bbc2d4129b 259 Gene3D G3DSA:1.10.601.10 11 110 5.9E-28 T 11-10-2018 AFK25_05275 3f24f2c16450a7e9016da6bbc2d4129b 259 SUPERFAMILY SSF88659 114 190 6.98E-16 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFK25_06480 b2f01f039ec3ab5e2d6eab424f8d6e12 691 SUPERFAMILY SSF55804 538 675 1.22E-21 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 AFK25_06480 b2f01f039ec3ab5e2d6eab424f8d6e12 691 Gene3D G3DSA:1.10.1790.10 315 411 9.8E-20 T 11-10-2018 AFK25_06480 b2f01f039ec3ab5e2d6eab424f8d6e12 691 SUPERFAMILY SSF63520 308 413 8.11E-23 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 AFK25_06480 b2f01f039ec3ab5e2d6eab424f8d6e12 691 SUPERFAMILY SSF63520 198 302 6.02E-24 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 AFK25_06480 b2f01f039ec3ab5e2d6eab424f8d6e12 691 SUPERFAMILY SSF46785 88 149 5.1E-7 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_06480 b2f01f039ec3ab5e2d6eab424f8d6e12 691 Gene3D G3DSA:1.10.10.10 73 150 2.5E-8 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_06480 b2f01f039ec3ab5e2d6eab424f8d6e12 691 Gene3D G3DSA:1.10.10.10 2 69 1.2E-6 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_06480 b2f01f039ec3ab5e2d6eab424f8d6e12 691 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 539 675 4.1E-19 T 11-10-2018 IPR002178 PTS EIIA type-2 domain AFK25_06480 b2f01f039ec3ab5e2d6eab424f8d6e12 691 Pfam PF08279 HTH domain 6 63 1.5E-8 T 11-10-2018 IPR013196 Helix-turn-helix, type 11 AFK25_06480 b2f01f039ec3ab5e2d6eab424f8d6e12 691 Pfam PF08279 HTH domain 92 147 2.5E-5 T 11-10-2018 IPR013196 Helix-turn-helix, type 11 AFK25_06480 b2f01f039ec3ab5e2d6eab424f8d6e12 691 Gene3D G3DSA:3.40.50.2300 417 499 1.8E-7 T 11-10-2018 AFK25_06480 b2f01f039ec3ab5e2d6eab424f8d6e12 691 SUPERFAMILY SSF46785 3 46 1.15E-5 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_06480 b2f01f039ec3ab5e2d6eab424f8d6e12 691 SUPERFAMILY SSF52794 417 489 3.56E-8 T 11-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 AFK25_06480 b2f01f039ec3ab5e2d6eab424f8d6e12 691 Pfam PF00874 PRD domain 212 298 1.2E-20 T 11-10-2018 IPR011608 PRD domain GO:0006355 AFK25_06480 b2f01f039ec3ab5e2d6eab424f8d6e12 691 Pfam PF00874 PRD domain 321 409 2.6E-20 T 11-10-2018 IPR011608 PRD domain GO:0006355 AFK25_06480 b2f01f039ec3ab5e2d6eab424f8d6e12 691 Gene3D G3DSA:1.10.1790.10 202 302 1.8E-21 T 11-10-2018 AFK25_06480 b2f01f039ec3ab5e2d6eab424f8d6e12 691 Gene3D G3DSA:3.40.930.10 529 677 9.0E-18 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 AFK25_08385 2576b9b87d7439ae8c4017e9e5a0d641 509 Gene3D G3DSA:2.60.40.420 31 346 8.2E-93 T 11-10-2018 IPR008972 Cupredoxin AFK25_08385 2576b9b87d7439ae8c4017e9e5a0d641 509 ProSitePatterns PS00080 Multicopper oxidases signature 2. 473 484 - T 11-10-2018 IPR002355 Multicopper oxidase, copper-binding site GO:0005507 AFK25_08385 2576b9b87d7439ae8c4017e9e5a0d641 509 SUPERFAMILY SSF49503 365 496 7.34E-38 T 11-10-2018 IPR008972 Cupredoxin AFK25_08385 2576b9b87d7439ae8c4017e9e5a0d641 509 Pfam PF00394 Multicopper oxidase 185 316 1.4E-15 T 11-10-2018 IPR001117 Multicopper oxidase, type 1 GO:0055114 AFK25_08385 2576b9b87d7439ae8c4017e9e5a0d641 509 Pfam PF07731 Multicopper oxidase 385 490 1.4E-30 T 11-10-2018 IPR011706 Multicopper oxidase, type 2 GO:0005507|GO:0016491|GO:0055114 AFK25_08385 2576b9b87d7439ae8c4017e9e5a0d641 509 SUPERFAMILY SSF49503 181 337 1.66E-30 T 11-10-2018 IPR008972 Cupredoxin AFK25_08385 2576b9b87d7439ae8c4017e9e5a0d641 509 Pfam PF07732 Multicopper oxidase 66 178 1.5E-36 T 11-10-2018 IPR011707 Multicopper oxidase, type 3 GO:0005507 AFK25_08385 2576b9b87d7439ae8c4017e9e5a0d641 509 SUPERFAMILY SSF49503 41 177 8.6E-39 T 11-10-2018 IPR008972 Cupredoxin AFK25_08385 2576b9b87d7439ae8c4017e9e5a0d641 509 ProSitePatterns PS00079 Multicopper oxidases signature 1. 468 488 - T 11-10-2018 IPR033138 Multicopper oxidases, conserved site AFK25_08385 2576b9b87d7439ae8c4017e9e5a0d641 509 Gene3D G3DSA:2.60.40.420 362 500 8.1E-42 T 11-10-2018 IPR008972 Cupredoxin AFK25_01335 57d16bfbaaba2d5dec2e2e6162a9b829 511 Pfam PF01808 AICARFT/IMPCHase bienzyme 134 445 5.3E-122 T 11-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFK25_01335 57d16bfbaaba2d5dec2e2e6162a9b829 511 SMART SM00798 134 446 2.0E-204 T 11-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFK25_01335 57d16bfbaaba2d5dec2e2e6162a9b829 511 PIRSF PIRSF000414 1 511 6.2E-218 T 11-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFK25_01335 57d16bfbaaba2d5dec2e2e6162a9b829 511 SUPERFAMILY SSF53927 207 511 3.71E-130 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFK25_01335 57d16bfbaaba2d5dec2e2e6162a9b829 511 TIGRFAM TIGR00355 purH: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase 3 511 6.6E-238 T 11-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFK25_01335 57d16bfbaaba2d5dec2e2e6162a9b829 511 SUPERFAMILY SSF52335 2 194 4.71E-70 T 11-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AFK25_01335 57d16bfbaaba2d5dec2e2e6162a9b829 511 Hamap MF_00139 Bifunctional purine biosynthesis protein PurH [purH]. 2 511 45.559 T 11-10-2018 IPR002695 Bifunctional purine biosynthesis protein PurH-like GO:0003937|GO:0004643|GO:0006164 KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFK25_01335 57d16bfbaaba2d5dec2e2e6162a9b829 511 Gene3D G3DSA:3.40.50.1380 1 196 5.1E-87 T 11-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AFK25_01335 57d16bfbaaba2d5dec2e2e6162a9b829 511 SMART SM00851 14 129 2.5E-56 T 11-10-2018 IPR011607 Methylglyoxal synthase-like domain AFK25_01335 57d16bfbaaba2d5dec2e2e6162a9b829 511 Gene3D G3DSA:3.40.140.20 204 360 1.2E-60 T 11-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFK25_01335 57d16bfbaaba2d5dec2e2e6162a9b829 511 Pfam PF02142 MGS-like domain 14 129 5.7E-28 T 11-10-2018 IPR011607 Methylglyoxal synthase-like domain AFK25_01335 57d16bfbaaba2d5dec2e2e6162a9b829 511 Gene3D G3DSA:3.40.140.20 378 511 8.0E-60 T 11-10-2018 IPR024051 AICAR transformylase, duplicated domain superfamily KEGG: 00230+3.5.4.10+2.1.2.3|KEGG: 00670+2.1.2.3|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFK25_11920 5a53be23afb937f40f7f484543ccd987 713 SUPERFAMILY SSF46785 640 706 1.03E-23 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_11920 5a53be23afb937f40f7f484543ccd987 713 Gene3D G3DSA:3.30.980.40 245 348 5.7E-36 T 11-10-2018 AFK25_11920 5a53be23afb937f40f7f484543ccd987 713 SMART SM00843 639 704 4.5E-41 T 11-10-2018 IPR018541 FtsK gamma domain AFK25_11920 5a53be23afb937f40f7f484543ccd987 713 Pfam PF09397 Ftsk gamma domain 641 701 2.6E-30 T 11-10-2018 IPR018541 FtsK gamma domain AFK25_11920 5a53be23afb937f40f7f484543ccd987 713 Gene3D G3DSA:1.10.10.10 632 700 9.3E-29 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_11920 5a53be23afb937f40f7f484543ccd987 713 Gene3D G3DSA:3.40.50.300 349 628 1.8E-115 T 11-10-2018 AFK25_11920 5a53be23afb937f40f7f484543ccd987 713 Pfam PF01580 FtsK/SpoIIIE family 352 490 4.7E-52 T 11-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 AFK25_11920 5a53be23afb937f40f7f484543ccd987 713 SUPERFAMILY SSF52540 326 616 1.22E-48 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_11920 5a53be23afb937f40f7f484543ccd987 713 SMART SM00382 387 565 0.001 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_06340 f2eb788383e7725739aefd53b1f36242 59 Pfam PF08141 Small acid-soluble spore protein H family 1 58 2.0E-27 T 11-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 AFK25_06340 f2eb788383e7725739aefd53b1f36242 59 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 59 3.0E-15 T 11-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 AFK25_06340 f2eb788383e7725739aefd53b1f36242 59 TIGRFAM TIGR02861 SASP_H: small acid-soluble spore protein, H-type 1 58 1.0E-26 T 11-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 AFK25_06340 f2eb788383e7725739aefd53b1f36242 59 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 59 19.488 T 11-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 AFK25_13410 ac84738fadc5cacf437ce8d617c5dd43 325 SUPERFAMILY SSF53474 54 318 1.27E-23 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold AFK25_13410 ac84738fadc5cacf437ce8d617c5dd43 325 Pfam PF09752 Abhydrolase domain containing 18 158 241 1.6E-6 T 11-10-2018 IPR019149 Abhydrolase domain containing 18 AFK25_13410 ac84738fadc5cacf437ce8d617c5dd43 325 Gene3D G3DSA:3.40.50.1820 48 316 3.2E-20 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold AFK25_05625 a264d19931fa973fd0f0b1f8c006147b 432 Pfam PF01134 Glucose inhibited division protein A 3 364 3.7E-118 T 11-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 AFK25_05625 a264d19931fa973fd0f0b1f8c006147b 432 Gene3D G3DSA:3.50.50.60 285 432 2.1E-55 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_05625 a264d19931fa973fd0f0b1f8c006147b 432 Gene3D G3DSA:3.50.50.60 1 175 7.2E-59 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_05625 a264d19931fa973fd0f0b1f8c006147b 432 TIGRFAM TIGR00137 gid_trmFO: tRNA:m(5)U-54 methyltransferase 2 430 5.7E-237 T 11-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 AFK25_05625 a264d19931fa973fd0f0b1f8c006147b 432 Hamap MF_01037 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO [trmFO]. 3 431 37.542 T 11-10-2018 IPR004417 Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO GO:0005737|GO:0008033|GO:0047151|GO:0050660 AFK25_05625 a264d19931fa973fd0f0b1f8c006147b 432 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 334 357 - T 11-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 AFK25_05625 a264d19931fa973fd0f0b1f8c006147b 432 SUPERFAMILY SSF51905 3 363 1.69E-29 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 SUPERFAMILY SSF55785 251 368 9.25E-14 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 262 374 6.2E-7 T 11-10-2018 IPR000014 PAS domain AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 Pfam PF13426 PAS domain 274 369 8.8E-9 T 11-10-2018 IPR000014 PAS domain AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 SUPERFAMILY SSF158472 205 253 1.16E-9 T 11-10-2018 AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 Pfam PF00512 His Kinase A (phospho-acceptor) domain 377 442 3.5E-19 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 SMART SM00387 488 600 2.1E-44 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 SMART SM00388 376 443 9.4E-22 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 Gene3D G3DSA:1.10.8.500 203 252 1.9E-9 T 11-10-2018 AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 SUPERFAMILY SSF55874 432 598 3.54E-48 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 SUPERFAMILY SSF47384 362 443 1.69E-20 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 Pfam PF00672 HAMP domain 205 253 3.3E-9 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 Gene3D G3DSA:3.30.450.20 253 371 2.2E-23 T 11-10-2018 AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 Gene3D G3DSA:1.10.287.130 372 446 3.4E-30 T 11-10-2018 AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 SMART SM00091 263 329 7.3E-7 T 11-10-2018 IPR000014 PAS domain AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 PRINTS PR00344 Bacterial sensor protein C-terminal signature 525 539 6.9E-18 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 PRINTS PR00344 Bacterial sensor protein C-terminal signature 584 597 6.9E-18 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 PRINTS PR00344 Bacterial sensor protein C-terminal signature 560 578 6.9E-18 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 PRINTS PR00344 Bacterial sensor protein C-terminal signature 543 553 6.9E-18 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 Gene3D G3DSA:3.30.565.10 447 603 1.6E-49 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 SMART SM00304 204 256 5.2E-12 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 Gene3D G3DSA:3.30.450.20 31 182 1.9E-52 T 11-10-2018 AFK25_14535 f8508007fb64f906bfeb31ba4f30dee7 604 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 489 599 1.3E-30 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_02715 5dd3d97d5c336479041ff23f361a8671 255 Pfam PF05690 Thiazole biosynthesis protein ThiG 4 248 3.7E-111 T 11-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 AFK25_02715 5dd3d97d5c336479041ff23f361a8671 255 Gene3D G3DSA:3.20.20.70 1 255 1.1E-118 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_02715 5dd3d97d5c336479041ff23f361a8671 255 SUPERFAMILY SSF110399 1 240 1.29E-84 T 11-10-2018 AFK25_02715 5dd3d97d5c336479041ff23f361a8671 255 Hamap MF_00443 Thiazole synthase [thiG]. 1 254 43.384 T 11-10-2018 IPR008867 Thiazole synthase GO:0009228 KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 AFK25_00375 da6ab0441ba6a4c98b01f42ca78c33ba 627 Pfam PF06480 FtsH Extracellular 9 101 1.4E-9 T 11-10-2018 IPR011546 Peptidase M41, FtsH extracellular GO:0004222|GO:0005524|GO:0008270|GO:0016021 Reactome: R-HSA-8949664 AFK25_00375 da6ab0441ba6a4c98b01f42ca78c33ba 627 SUPERFAMILY SSF140990 412 608 9.55E-77 T 11-10-2018 IPR037219 Peptidase M41-like GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 AFK25_00375 da6ab0441ba6a4c98b01f42ca78c33ba 627 ProSitePatterns PS00674 AAA-protein family signature. 301 319 - T 11-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AFK25_00375 da6ab0441ba6a4c98b01f42ca78c33ba 627 Pfam PF01434 Peptidase family M41 392 600 1.2E-88 T 11-10-2018 IPR000642 Peptidase M41 GO:0004222|GO:0005524|GO:0006508 Reactome: R-HSA-8949664 AFK25_00375 da6ab0441ba6a4c98b01f42ca78c33ba 627 Gene3D G3DSA:1.10.8.60 332 409 6.4E-31 T 11-10-2018 AFK25_00375 da6ab0441ba6a4c98b01f42ca78c33ba 627 SUPERFAMILY SSF52540 154 402 2.02E-75 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_00375 da6ab0441ba6a4c98b01f42ca78c33ba 627 Gene3D G3DSA:3.40.50.300 149 331 2.3E-71 T 11-10-2018 AFK25_00375 da6ab0441ba6a4c98b01f42ca78c33ba 627 SMART SM00382 194 333 5.8E-26 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_00375 da6ab0441ba6a4c98b01f42ca78c33ba 627 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 198 330 1.2E-46 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFK25_00375 da6ab0441ba6a4c98b01f42ca78c33ba 627 Hamap MF_01458 ATP-dependent zinc metalloprotease FtsH [ftsH]. 3 609 39.189 T 11-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 AFK25_00375 da6ab0441ba6a4c98b01f42ca78c33ba 627 TIGRFAM TIGR01241 FtsH_fam: ATP-dependent metallopeptidase HflB 110 601 7.3E-250 T 11-10-2018 IPR005936 Peptidase, FtsH GO:0004222|GO:0016020 Reactome: R-HSA-8949664 AFK25_00375 da6ab0441ba6a4c98b01f42ca78c33ba 627 Gene3D G3DSA:1.20.58.760 412 616 8.4E-78 T 11-10-2018 AFK25_01010 547a603a60c110b9bc16db715eb88402 546 Gene3D G3DSA:3.30.300.310 438 542 7.9E-34 T 11-10-2018 AFK25_01010 547a603a60c110b9bc16db715eb88402 546 Gene3D G3DSA:3.40.50.980 34 208 1.6E-125 T 11-10-2018 AFK25_01010 547a603a60c110b9bc16db715eb88402 546 Gene3D G3DSA:2.30.38.10 352 435 1.6E-125 T 11-10-2018 AFK25_01010 547a603a60c110b9bc16db715eb88402 546 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 526 1.1E-17 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFK25_01010 547a603a60c110b9bc16db715eb88402 546 SUPERFAMILY SSF56801 4 539 1.44E-163 T 11-10-2018 AFK25_01010 547a603a60c110b9bc16db715eb88402 546 ProSitePatterns PS00455 Putative AMP-binding domain signature. 192 203 - T 11-10-2018 IPR020845 AMP-binding, conserved site AFK25_01010 547a603a60c110b9bc16db715eb88402 546 Gene3D G3DSA:3.40.50.980 31 351 1.6E-125 T 11-10-2018 AFK25_01010 547a603a60c110b9bc16db715eb88402 546 Pfam PF00501 AMP-binding enzyme 11 442 1.7E-113 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFK25_04795 967ea509bbbdafb1a5aec1ce3925ae43 251 Gene3D G3DSA:3.40.50.720 1 249 8.5E-81 T 11-10-2018 AFK25_04795 967ea509bbbdafb1a5aec1ce3925ae43 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 3.4E-6 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04795 967ea509bbbdafb1a5aec1ce3925ae43 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 3.4E-6 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04795 967ea509bbbdafb1a5aec1ce3925ae43 251 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 3.4E-6 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04795 967ea509bbbdafb1a5aec1ce3925ae43 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.4E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04795 967ea509bbbdafb1a5aec1ce3925ae43 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 2.4E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04795 967ea509bbbdafb1a5aec1ce3925ae43 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 2.4E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04795 967ea509bbbdafb1a5aec1ce3925ae43 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 5 22 2.4E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04795 967ea509bbbdafb1a5aec1ce3925ae43 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 2.4E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04795 967ea509bbbdafb1a5aec1ce3925ae43 251 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 208 228 2.4E-35 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04795 967ea509bbbdafb1a5aec1ce3925ae43 251 SUPERFAMILY SSF51735 2 246 2.38E-82 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_04795 967ea509bbbdafb1a5aec1ce3925ae43 251 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 243 3.9E-59 T 11-10-2018 AFK25_00285 45c7e1d646708800d1db0259f7415c85 187 Gene3D G3DSA:3.40.50.1470 1 187 6.8E-75 T 11-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 AFK25_00285 45c7e1d646708800d1db0259f7415c85 187 Hamap MF_00083 Peptidyl-tRNA hydrolase [pth]. 2 179 37.664 T 11-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 AFK25_00285 45c7e1d646708800d1db0259f7415c85 187 Pfam PF01195 Peptidyl-tRNA hydrolase 4 186 5.1E-63 T 11-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 AFK25_00285 45c7e1d646708800d1db0259f7415c85 187 ProSitePatterns PS01196 Peptidyl-tRNA hydrolase signature 2. 108 118 - T 11-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 AFK25_00285 45c7e1d646708800d1db0259f7415c85 187 SUPERFAMILY SSF53178 2 186 8.24E-73 T 11-10-2018 IPR036416 Peptidyl-tRNA hydrolase superfamily GO:0004045 MetaCyc: PWY-6308 AFK25_00285 45c7e1d646708800d1db0259f7415c85 187 ProSitePatterns PS01195 Peptidyl-tRNA hydrolase signature 1. 15 28 - T 11-10-2018 IPR018171 Peptidyl-tRNA hydrolase, conserved site GO:0004045 MetaCyc: PWY-6308 AFK25_00285 45c7e1d646708800d1db0259f7415c85 187 TIGRFAM TIGR00447 pth: aminoacyl-tRNA hydrolase 3 186 4.6E-74 T 11-10-2018 IPR001328 Peptidyl-tRNA hydrolase GO:0004045 MetaCyc: PWY-6308 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 PRINTS PR00941 Cadmium-transporting ATPase signature 185 205 6.1E-77 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 PRINTS PR00941 Cadmium-transporting ATPase signature 49 72 6.1E-77 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 PRINTS PR00941 Cadmium-transporting ATPase signature 114 131 6.1E-77 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 PRINTS PR00941 Cadmium-transporting ATPase signature 266 282 6.1E-77 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 PRINTS PR00941 Cadmium-transporting ATPase signature 285 299 6.1E-77 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 PRINTS PR00941 Cadmium-transporting ATPase signature 27 48 6.1E-77 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 PRINTS PR00941 Cadmium-transporting ATPase signature 16 25 6.1E-77 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 PRINTS PR00941 Cadmium-transporting ATPase signature 205 221 6.1E-77 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 PRINTS PR00941 Cadmium-transporting ATPase signature 131 143 6.1E-77 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 151 465 1.0E-98 T 11-10-2018 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 Gene3D G3DSA:2.70.150.20 187 304 1.1E-36 T 11-10-2018 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 Gene3D G3DSA:3.40.50.1000 382 656 6.1E-92 T 11-10-2018 IPR023214 HAD superfamily AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 SUPERFAMILY SSF81665 150 694 1.02E-20 T 11-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 150 707 3.1E-192 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 132 707 6.3E-127 T 11-10-2018 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 SUPERFAMILY SSF56784 399 705 2.06E-57 T 11-10-2018 IPR036412 HAD-like superfamily AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 173 685 3.7E-98 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 Gene3D G3DSA:3.30.70.100 11 80 7.5E-18 T 11-10-2018 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 Pfam PF00702 haloacid dehalogenase-like hydrolase 398 616 3.8E-47 T 11-10-2018 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 551 561 8.4E-24 T 11-10-2018 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 604 623 8.4E-24 T 11-10-2018 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 250 264 8.4E-24 T 11-10-2018 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 628 640 8.4E-24 T 11-10-2018 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 528 539 8.4E-24 T 11-10-2018 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 401 415 8.4E-24 T 11-10-2018 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 SUPERFAMILY SSF81653 203 300 2.35E-26 T 11-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 SUPERFAMILY SSF55008 10 66 5.37E-12 T 11-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 403 409 - T 11-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 Gene3D G3DSA:3.40.1110.10 412 535 6.1E-92 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 ProSitePatterns PS01047 Heavy-metal-associated domain. 18 47 - T 11-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 Pfam PF00122 E1-E2 ATPase 202 381 1.5E-54 T 11-10-2018 AFK25_04075 66b0729d4beabcc5faa82dfb08fb46b3 712 Pfam PF00403 Heavy-metal-associated domain 15 65 4.9E-11 T 11-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 SUPERFAMILY SSF52343 436 591 7.99E-52 T 11-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 411 420 3.5E-29 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 259 269 3.5E-29 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 378 385 3.5E-29 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 448 467 3.5E-29 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 540 548 3.5E-29 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 473 482 3.5E-29 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 517 533 3.5E-29 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 PRINTS PR00371 Flavoprotein pyridine nucleotide cytochrome reductase signature 486 497 3.5E-29 T 11-10-2018 IPR001709 Flavoprotein pyridine nucleotide cytochrome reductase GO:0016491|GO:0055114 AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 Gene3D G3DSA:3.40.50.80 437 591 3.2E-59 T 11-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 PRINTS PR00369 Flavodoxin signature 106 117 6.9E-17 T 11-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 PRINTS PR00369 Flavodoxin signature 138 148 6.9E-17 T 11-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 PRINTS PR00369 Flavodoxin signature 162 181 6.9E-17 T 11-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 PRINTS PR00369 Flavodoxin signature 58 71 6.9E-17 T 11-10-2018 IPR001094 Flavodoxin-like GO:0010181|GO:0055114 AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 PIRSF PIRSF000207 1 591 1.0E-262 T 11-10-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 SUPERFAMILY SSF63380 217 437 4.02E-66 T 11-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 Pfam PF00258 Flavodoxin 59 190 1.2E-34 T 11-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 Gene3D G3DSA:2.40.30.10 221 431 8.4E-76 T 11-10-2018 AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 Pfam PF00667 FAD binding domain 221 416 7.4E-36 T 11-10-2018 IPR003097 Sulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-binding GO:0016491|GO:0055114 AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 Pfam PF00175 Oxidoreductase NAD-binding domain 449 555 6.5E-18 T 11-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 Gene3D G3DSA:1.20.990.10 269 376 8.4E-76 T 11-10-2018 IPR023173 NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily GO:0016491|GO:0055114 AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 Gene3D G3DSA:3.40.50.360 47 210 8.5E-55 T 11-10-2018 IPR029039 Flavoprotein-like superfamily AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 SUPERFAMILY SSF52218 55 198 6.29E-51 T 11-10-2018 IPR029039 Flavoprotein-like superfamily AFK25_06350 5ad4d22515c474faecce02c877e45d42 591 TIGRFAM TIGR01931 cysJ: sulfite reductase [NADPH] flavoprotein, alpha-component 7 591 1.3E-256 T 11-10-2018 IPR010199 Sulphite reductase [NADPH] flavoprotein, alpha chain GO:0004783|GO:0010181|GO:0019344|GO:0050660|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFK25_14605 4cd9f1b0d8abf2d140ce193a37ab9d73 291 SUPERFAMILY SSF82861 29 118 6.67E-15 T 11-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 AFK25_14605 4cd9f1b0d8abf2d140ce193a37ab9d73 291 Gene3D G3DSA:3.30.70.100 185 272 8.3E-29 T 11-10-2018 AFK25_14605 4cd9f1b0d8abf2d140ce193a37ab9d73 291 SUPERFAMILY SSF50182 120 182 3.24E-15 T 11-10-2018 IPR010920 LSM domain superfamily AFK25_14605 4cd9f1b0d8abf2d140ce193a37ab9d73 291 Gene3D G3DSA:2.30.30.60 135 183 1.8E-23 T 11-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily AFK25_14605 4cd9f1b0d8abf2d140ce193a37ab9d73 291 Pfam PF00924 Mechanosensitive ion channel 77 274 3.9E-50 T 11-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AFK25_14605 4cd9f1b0d8abf2d140ce193a37ab9d73 291 SUPERFAMILY SSF82689 185 284 4.84E-23 T 11-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 AFK25_02820 57ed2835705f25289a4535cf3aa35b38 203 SUPERFAMILY SSF46785 13 146 6.82E-23 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_02820 57ed2835705f25289a4535cf3aa35b38 203 Pfam PF01047 MarR family 48 105 1.2E-14 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_02820 57ed2835705f25289a4535cf3aa35b38 203 Hamap MF_01911 HTH-type transcriptional regulator Hpr [hpr]. 6 189 49.467 T 11-10-2018 IPR023488 HTH-type transcriptional regulator Hpr AFK25_02820 57ed2835705f25289a4535cf3aa35b38 203 SMART SM00347 41 141 4.2E-19 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_02820 57ed2835705f25289a4535cf3aa35b38 203 Gene3D G3DSA:1.10.10.10 3 171 4.7E-47 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_02820 57ed2835705f25289a4535cf3aa35b38 203 ProSitePatterns PS01117 MarR-type HTH domain signature. 80 114 - T 11-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site AFK25_04360 378bb08117c3a4030b947be7d6f506a7 578 Pfam PF11563 Protoglobin 23 170 1.9E-21 T 11-10-2018 AFK25_04360 378bb08117c3a4030b947be7d6f506a7 578 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 248 415 1.5E-36 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_04360 378bb08117c3a4030b947be7d6f506a7 578 Pfam PF13682 Chemoreceptor zinc-binding domain 464 530 7.4E-17 T 11-10-2018 IPR025991 Chemoreceptor zinc-binding domain AFK25_04360 378bb08117c3a4030b947be7d6f506a7 578 Gene3D G3DSA:1.10.287.950 198 443 1.3E-44 T 11-10-2018 AFK25_04360 378bb08117c3a4030b947be7d6f506a7 578 SMART SM00283 186 440 5.1E-45 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_04360 378bb08117c3a4030b947be7d6f506a7 578 Gene3D G3DSA:1.10.490.10 25 175 2.5E-9 T 11-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 AFK25_04360 378bb08117c3a4030b947be7d6f506a7 578 SUPERFAMILY SSF46458 25 163 2.45E-9 T 11-10-2018 IPR009050 Globin-like superfamily AFK25_04360 378bb08117c3a4030b947be7d6f506a7 578 Gene3D G3DSA:1.20.120.30 444 571 3.1E-7 T 11-10-2018 AFK25_04360 378bb08117c3a4030b947be7d6f506a7 578 SUPERFAMILY SSF58104 192 439 1.31E-58 T 11-10-2018 AFK25_11910 34e9db4f1042c1146c3408bb7dfb0270 433 Hamap MF_00046 UDP-N-acetylmuramate--L-alanine ligase [murC]. 1 433 35.201 T 11-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFK25_11910 34e9db4f1042c1146c3408bb7dfb0270 433 SUPERFAMILY SSF53623 87 292 8.24E-60 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFK25_11910 34e9db4f1042c1146c3408bb7dfb0270 433 Pfam PF02875 Mur ligase family, glutamate ligase domain 296 376 2.4E-19 T 11-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 AFK25_11910 34e9db4f1042c1146c3408bb7dfb0270 433 SUPERFAMILY SSF53244 294 427 1.26E-36 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFK25_11910 34e9db4f1042c1146c3408bb7dfb0270 433 SUPERFAMILY SSF51984 4 88 6.28E-21 T 11-10-2018 AFK25_11910 34e9db4f1042c1146c3408bb7dfb0270 433 TIGRFAM TIGR01082 murC: UDP-N-acetylmuramate--L-alanine ligase 4 428 1.7E-135 T 11-10-2018 IPR005758 UDP-N-acetylmuramate--L-alanine ligase GO:0008763|GO:0009252 KEGG: 00471+6.3.2.8|KEGG: 00550+6.3.2.8|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFK25_11910 34e9db4f1042c1146c3408bb7dfb0270 433 Pfam PF01225 Mur ligase family, catalytic domain 4 101 5.7E-22 T 11-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AFK25_11910 34e9db4f1042c1146c3408bb7dfb0270 433 Pfam PF08245 Mur ligase middle domain 106 275 2.5E-26 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 AFK25_11910 34e9db4f1042c1146c3408bb7dfb0270 433 Gene3D G3DSA:3.40.1190.10 91 291 9.9E-55 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFK25_11910 34e9db4f1042c1146c3408bb7dfb0270 433 Gene3D G3DSA:3.90.190.20 292 432 8.8E-40 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFK25_11910 34e9db4f1042c1146c3408bb7dfb0270 433 Gene3D G3DSA:3.40.50.720 3 89 2.8E-21 T 11-10-2018 AFK25_09360 77f740bbdcd00f44581a4d6f6df6478b 287 Pfam PF06207 Protein of unknown function (DUF1002) 32 249 3.7E-80 T 11-10-2018 IPR009343 Protein of unknown function DUF1002 AFK25_07955 53ad5848b115b284e278a247c0b2df12 502 Pfam PF00005 ABC transporter 19 170 5.2E-33 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_07955 53ad5848b115b284e278a247c0b2df12 502 Pfam PF00005 ABC transporter 276 430 4.0E-21 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_07955 53ad5848b115b284e278a247c0b2df12 502 ProSitePatterns PS00211 ABC transporters family signature. 403 417 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_07955 53ad5848b115b284e278a247c0b2df12 502 Gene3D G3DSA:3.40.50.300 243 499 1.5E-46 T 11-10-2018 AFK25_07955 53ad5848b115b284e278a247c0b2df12 502 Gene3D G3DSA:3.40.50.300 1 242 4.6E-58 T 11-10-2018 AFK25_07955 53ad5848b115b284e278a247c0b2df12 502 SUPERFAMILY SSF52540 3 230 4.28E-58 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_07955 53ad5848b115b284e278a247c0b2df12 502 SUPERFAMILY SSF52540 241 491 8.3E-48 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_07955 53ad5848b115b284e278a247c0b2df12 502 SMART SM00382 284 486 5.0E-5 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_07955 53ad5848b115b284e278a247c0b2df12 502 SMART SM00382 28 218 5.4E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_05850 1f1483bee4b458e1ff623d7c42fd7783 381 Pfam PF13288 DXP reductoisomerase C-terminal domain 258 374 1.3E-43 T 11-10-2018 IPR026877 DXP reductoisomerase C-terminal domain KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFK25_05850 1f1483bee4b458e1ff623d7c42fd7783 381 SUPERFAMILY SSF51735 2 147 3.15E-43 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_05850 1f1483bee4b458e1ff623d7c42fd7783 381 Pfam PF08436 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal 143 226 7.3E-44 T 11-10-2018 IPR013644 1-deoxy-D-xylulose 5-phosphate reductoisomerase, C-terminal GO:0005515 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFK25_05850 1f1483bee4b458e1ff623d7c42fd7783 381 TIGRFAM TIGR00243 Dxr: 1-deoxy-D-xylulose 5-phosphate reductoisomerase 2 377 4.7E-172 T 11-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFK25_05850 1f1483bee4b458e1ff623d7c42fd7783 381 Pfam PF02670 1-deoxy-D-xylulose 5-phosphate reductoisomerase 4 129 1.5E-44 T 11-10-2018 IPR013512 1-deoxy-D-xylulose 5-phosphate reductoisomerase, N-terminal GO:0055114|GO:0070402 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFK25_05850 1f1483bee4b458e1ff623d7c42fd7783 381 SUPERFAMILY SSF55347 123 261 2.45E-62 T 11-10-2018 AFK25_05850 1f1483bee4b458e1ff623d7c42fd7783 381 Gene3D G3DSA:1.10.1740.10 299 381 1.2E-27 T 11-10-2018 AFK25_05850 1f1483bee4b458e1ff623d7c42fd7783 381 PIRSF PIRSF006205 1 381 6.4E-167 T 11-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFK25_05850 1f1483bee4b458e1ff623d7c42fd7783 381 SUPERFAMILY SSF69055 289 379 8.11E-31 T 11-10-2018 IPR036169 DXP reductoisomerase, C-terminal domain superfamily KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFK25_05850 1f1483bee4b458e1ff623d7c42fd7783 381 Hamap MF_00183 1-deoxy-D-xylulose 5-phosphate reductoisomerase [dxr]. 4 379 47.691 T 11-10-2018 IPR003821 1-deoxy-D-xylulose 5-phosphate reductoisomerase GO:0008299|GO:0030604|GO:0046872|GO:0055114 KEGG: 00900+1.1.1.267|MetaCyc: PWY-7560 AFK25_05850 1f1483bee4b458e1ff623d7c42fd7783 381 Gene3D G3DSA:3.40.50.720 1 147 1.0E-51 T 11-10-2018 AFK25_12315 ec08d5446aad82de15eabe18d90f7b9f 648 SUPERFAMILY SSF51011 519 622 3.39E-33 T 11-10-2018 AFK25_12315 ec08d5446aad82de15eabe18d90f7b9f 648 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 30 112 1.3E-22 T 11-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 AFK25_12315 ec08d5446aad82de15eabe18d90f7b9f 648 SUPERFAMILY SSF81296 43 116 1.33E-11 T 11-10-2018 IPR014756 Immunoglobulin E-set AFK25_12315 ec08d5446aad82de15eabe18d90f7b9f 648 TIGRFAM TIGR01515 branching_enzym: 1,4-alpha-glucan branching enzyme 15 621 4.1E-272 T 11-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 AFK25_12315 ec08d5446aad82de15eabe18d90f7b9f 648 Pfam PF00128 Alpha amylase, catalytic domain 276 476 1.1E-4 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFK25_12315 ec08d5446aad82de15eabe18d90f7b9f 648 Pfam PF00128 Alpha amylase, catalytic domain 181 255 3.7E-9 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFK25_12315 ec08d5446aad82de15eabe18d90f7b9f 648 SMART SM00642 156 506 2.2E-7 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFK25_12315 ec08d5446aad82de15eabe18d90f7b9f 648 Pfam PF02806 Alpha amylase, C-terminal all-beta domain 524 621 5.4E-19 T 11-10-2018 IPR006048 Alpha-amylase/branching enzyme, C-terminal all beta GO:0003824|GO:0005975|GO:0043169 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 AFK25_12315 ec08d5446aad82de15eabe18d90f7b9f 648 SUPERFAMILY SSF51445 89 512 2.69E-110 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily AFK25_12315 ec08d5446aad82de15eabe18d90f7b9f 648 Gene3D G3DSA:2.60.40.10 1 126 4.7E-45 T 11-10-2018 IPR013783 Immunoglobulin-like fold AFK25_12315 ec08d5446aad82de15eabe18d90f7b9f 648 Hamap MF_00685 1,4-alpha-glucan branching enzyme GlgB [glgB]. 8 623 41.155 T 11-10-2018 IPR006407 1,4-alpha-glucan-branching enzyme, GlgB GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900 AFK25_12315 ec08d5446aad82de15eabe18d90f7b9f 648 PIRSF PIRSF000463 3 632 9.2E-270 T 11-10-2018 IPR037439 1,4-alpha-glucan-branching enzyme GO:0003844|GO:0005978 KEGG: 00500+2.4.1.18|MetaCyc: PWY-5067|MetaCyc: PWY-622|MetaCyc: PWY-7900|Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 AFK25_12315 ec08d5446aad82de15eabe18d90f7b9f 648 Gene3D G3DSA:2.60.40.1180 519 623 8.3E-35 T 11-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFK25_12315 ec08d5446aad82de15eabe18d90f7b9f 648 Gene3D G3DSA:3.20.20.80 129 518 8.2E-151 T 11-10-2018 AFK25_05830 64be0e34620d20af674a55d45be7767f 240 TIGRFAM TIGR02075 pyrH_bact: UMP kinase 6 237 9.3E-105 T 11-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 AFK25_05830 64be0e34620d20af674a55d45be7767f 240 Hamap MF_01220_B Uridylate kinase [pyrH]. 4 238 45.959 T 11-10-2018 IPR015963 Uridylate kinase, bacteria GO:0005737|GO:0006221|GO:0033862 KEGG: 00240+2.7.4.22 AFK25_05830 64be0e34620d20af674a55d45be7767f 240 Pfam PF00696 Amino acid kinase family 7 217 9.1E-30 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AFK25_05830 64be0e34620d20af674a55d45be7767f 240 SUPERFAMILY SSF53633 4 238 2.23E-77 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFK25_05830 64be0e34620d20af674a55d45be7767f 240 Gene3D G3DSA:3.40.1160.10 1 239 1.4E-85 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFK25_05830 64be0e34620d20af674a55d45be7767f 240 PIRSF PIRSF005650 1 240 1.9E-100 T 11-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 AFK25_01825 5f5c86a0b41ff19cc86eb187f9a937bf 134 PRINTS PR00502 NUDIX hydrolase family signature 48 63 1.0E-7 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFK25_01825 5f5c86a0b41ff19cc86eb187f9a937bf 134 PRINTS PR00502 NUDIX hydrolase family signature 34 48 1.0E-7 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFK25_01825 5f5c86a0b41ff19cc86eb187f9a937bf 134 Pfam PF00293 NUDIX domain 5 121 7.8E-20 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFK25_01825 5f5c86a0b41ff19cc86eb187f9a937bf 134 SUPERFAMILY SSF55811 2 128 3.38E-35 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFK25_01825 5f5c86a0b41ff19cc86eb187f9a937bf 134 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFK25_01825 5f5c86a0b41ff19cc86eb187f9a937bf 134 Gene3D G3DSA:3.90.79.10 2 128 2.0E-36 T 11-10-2018 AFK25_00635 18cb85a80d82efcfafa2677f4640ff96 218 Pfam PF00189 Ribosomal protein S3, C-terminal domain 119 201 1.1E-40 T 11-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00635 18cb85a80d82efcfafa2677f4640ff96 218 TIGRFAM TIGR01009 rpsC_bact: ribosomal protein uS3 1 208 2.3E-97 T 11-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 AFK25_00635 18cb85a80d82efcfafa2677f4640ff96 218 SMART SM00322 59 124 1.7E-9 T 11-10-2018 IPR004087 K Homology domain GO:0003676 AFK25_00635 18cb85a80d82efcfafa2677f4640ff96 218 Gene3D G3DSA:3.30.300.20 17 106 1.6E-33 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta AFK25_00635 18cb85a80d82efcfafa2677f4640ff96 218 Gene3D G3DSA:3.30.1140.32 107 207 2.0E-41 T 11-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00635 18cb85a80d82efcfafa2677f4640ff96 218 Hamap MF_01309_B 30S ribosomal protein S3 [rpsC]. 1 205 39.194 T 11-10-2018 IPR005704 Ribosomal protein S3, bacterial GO:0003735|GO:0006412|GO:0015935 AFK25_00635 18cb85a80d82efcfafa2677f4640ff96 218 ProSitePatterns PS00548 Ribosomal protein S3 signature. 162 196 - T 11-10-2018 IPR018280 Ribosomal protein S3, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00635 18cb85a80d82efcfafa2677f4640ff96 218 SUPERFAMILY SSF54814 2 105 2.09E-40 T 11-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AFK25_00635 18cb85a80d82efcfafa2677f4640ff96 218 SUPERFAMILY SSF54821 106 205 8.5E-39 T 11-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00635 18cb85a80d82efcfafa2677f4640ff96 218 Pfam PF07650 KH domain 37 109 5.3E-23 T 11-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_13830 7a75a585c52c512e369937ee0b120297 134 Hamap MF_00530 ATP synthase epsilon chain [atpC]. 2 129 24.489 T 11-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13830 7a75a585c52c512e369937ee0b120297 134 Gene3D G3DSA:1.20.5.440 89 132 9.9E-18 T 11-10-2018 AFK25_13830 7a75a585c52c512e369937ee0b120297 134 TIGRFAM TIGR01216 ATP_synt_epsi: ATP synthase F1, epsilon subunit 3 130 1.0E-42 T 11-10-2018 IPR001469 ATP synthase, F1 complex, delta/epsilon subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13830 7a75a585c52c512e369937ee0b120297 134 SUPERFAMILY SSF46604 87 131 2.51E-9 T 11-10-2018 IPR036794 ATP synthase delta/epsilon subunit, C-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13830 7a75a585c52c512e369937ee0b120297 134 Pfam PF02823 ATP synthase, Delta/Epsilon chain, beta-sandwich domain 4 82 7.7E-30 T 11-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13830 7a75a585c52c512e369937ee0b120297 134 Gene3D G3DSA:2.60.15.10 1 88 2.0E-34 T 11-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13830 7a75a585c52c512e369937ee0b120297 134 ProDom PD000944 ATP SYNTHASE ION EPSILON SUBUNIT HYDROLASE CF1 SYNTHESIS CHAIN HYDROGEN 9 88 3.0E-33 T 11-10-2018 IPR020546 ATP synthase, F1 complex, delta/epsilon subunit, N-terminal GO:0015986 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13830 7a75a585c52c512e369937ee0b120297 134 SUPERFAMILY SSF51344 2 84 1.05E-24 T 11-10-2018 IPR036771 F0F1 ATP synthase delta/epsilon subunit, N-terminal Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13830 7a75a585c52c512e369937ee0b120297 134 Pfam PF00401 ATP synthase, Delta/Epsilon chain, long alpha-helix domain 86 130 1.6E-16 T 11-10-2018 IPR020547 ATP synthase delta/epsilon subunit, C-terminal domain AFK25_06590 d5a7c86bf7d8ff11490ecdca953726cd 420 Hamap MF_00372 Imidazolonepropionase [hutI]. 3 409 44.804 T 11-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFK25_06590 d5a7c86bf7d8ff11490ecdca953726cd 420 Gene3D G3DSA:2.30.40.10 7 407 3.9E-177 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFK25_06590 d5a7c86bf7d8ff11490ecdca953726cd 420 Gene3D G3DSA:3.20.20.140 72 369 3.9E-177 T 11-10-2018 AFK25_06590 d5a7c86bf7d8ff11490ecdca953726cd 420 SUPERFAMILY SSF51338 1 413 9.41E-25 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFK25_06590 d5a7c86bf7d8ff11490ecdca953726cd 420 Pfam PF01979 Amidohydrolase family 68 409 6.4E-20 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFK25_06590 d5a7c86bf7d8ff11490ecdca953726cd 420 SUPERFAMILY SSF51556 71 367 1.14E-83 T 11-10-2018 IPR032466 Metal-dependent hydrolase AFK25_06590 d5a7c86bf7d8ff11490ecdca953726cd 420 TIGRFAM TIGR01224 hutI: imidazolonepropionase 32 408 5.0E-158 T 11-10-2018 IPR005920 Imidazolonepropionase GO:0005737|GO:0016812|GO:0019556 KEGG: 00340+3.5.2.7|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFK25_11525 f1520e639aae649be6a259f7862a650b 166 Gene3D G3DSA:3.30.110.10 74 166 2.1E-39 T 11-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 AFK25_11525 f1520e639aae649be6a259f7862a650b 166 TIGRFAM TIGR00168 infC: translation initiation factor IF-3 2 164 2.6E-75 T 11-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AFK25_11525 f1520e639aae649be6a259f7862a650b 166 SUPERFAMILY SSF54364 2 73 6.67E-30 T 11-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AFK25_11525 f1520e639aae649be6a259f7862a650b 166 Pfam PF00707 Translation initiation factor IF-3, C-terminal domain 78 163 2.5E-39 T 11-10-2018 IPR019815 Translation initiation factor 3, C-terminal GO:0006413 Reactome: R-HSA-5368286 AFK25_11525 f1520e639aae649be6a259f7862a650b 166 SUPERFAMILY SSF55200 77 166 1.96E-34 T 11-10-2018 IPR036788 Translation initiation factor 3 (IF-3), C-terminal domain superfamily GO:0006413 Reactome: R-HSA-5368286 AFK25_11525 f1520e639aae649be6a259f7862a650b 166 Hamap MF_00080 Translation initiation factor IF-3 [infC]. 1 165 30.27 T 11-10-2018 IPR001288 Translation initiation factor 3 GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AFK25_11525 f1520e639aae649be6a259f7862a650b 166 ProSitePatterns PS00938 Initiation factor 3 signature. 53 66 - T 11-10-2018 IPR019813 Translation initiation factor 3, conserved site GO:0003743|GO:0006413 AFK25_11525 f1520e639aae649be6a259f7862a650b 166 Gene3D G3DSA:3.10.20.80 1 73 5.8E-35 T 11-10-2018 IPR036787 Translation initiation factor 3 (IF-3), N-terminal domain superfamily GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AFK25_11525 f1520e639aae649be6a259f7862a650b 166 Pfam PF05198 Translation initiation factor IF-3, N-terminal domain 2 71 2.8E-34 T 11-10-2018 IPR019814 Translation initiation factor 3, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-5368286 AFK25_11075 f0c73c6673f3cc7d27e2c8ca33567c9e 874 SUPERFAMILY SSF47323 571 823 1.57E-78 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_11075 f0c73c6673f3cc7d27e2c8ca33567c9e 874 TIGRFAM TIGR00422 valS: valine--tRNA ligase 3 855 0.0 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFK25_11075 f0c73c6673f3cc7d27e2c8ca33567c9e 874 SUPERFAMILY SSF52374 3 569 7.66E-146 T 11-10-2018 AFK25_11075 f0c73c6673f3cc7d27e2c8ca33567c9e 874 SUPERFAMILY SSF50677 191 341 4.32E-66 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFK25_11075 f0c73c6673f3cc7d27e2c8ca33567c9e 874 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_11075 f0c73c6673f3cc7d27e2c8ca33567c9e 874 Hamap MF_02004 Valine--tRNA ligase [valS]. 2 873 16.355 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFK25_11075 f0c73c6673f3cc7d27e2c8ca33567c9e 874 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 15 559 7.6E-227 T 11-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_11075 f0c73c6673f3cc7d27e2c8ca33567c9e 874 Gene3D G3DSA:1.10.730.10 2 736 0.0 T 11-10-2018 AFK25_11075 f0c73c6673f3cc7d27e2c8ca33567c9e 874 SUPERFAMILY SSF46589 808 872 7.32E-17 T 11-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 AFK25_11075 f0c73c6673f3cc7d27e2c8ca33567c9e 874 PRINTS PR00986 Valyl-tRNA synthetase signature 230 247 1.2E-40 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFK25_11075 f0c73c6673f3cc7d27e2c8ca33567c9e 874 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 1.2E-40 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFK25_11075 f0c73c6673f3cc7d27e2c8ca33567c9e 874 PRINTS PR00986 Valyl-tRNA synthetase signature 345 358 1.2E-40 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFK25_11075 f0c73c6673f3cc7d27e2c8ca33567c9e 874 PRINTS PR00986 Valyl-tRNA synthetase signature 439 460 1.2E-40 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFK25_11075 f0c73c6673f3cc7d27e2c8ca33567c9e 874 PRINTS PR00986 Valyl-tRNA synthetase signature 471 489 1.2E-40 T 11-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AFK25_11075 f0c73c6673f3cc7d27e2c8ca33567c9e 874 Gene3D G3DSA:3.90.740.10 175 341 0.0 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFK25_11075 f0c73c6673f3cc7d27e2c8ca33567c9e 874 Gene3D G3DSA:1.10.287.380 801 873 7.2E-26 T 11-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 AFK25_11075 f0c73c6673f3cc7d27e2c8ca33567c9e 874 Pfam PF08264 Anticodon-binding domain of tRNA 602 748 1.7E-44 T 11-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AFK25_11075 f0c73c6673f3cc7d27e2c8ca33567c9e 874 Pfam PF10458 Valyl tRNA synthetase tRNA binding arm 808 873 3.4E-24 T 11-10-2018 IPR019499 Valyl-tRNA synthetase, tRNA-binding arm GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9 AFK25_11075 f0c73c6673f3cc7d27e2c8ca33567c9e 874 Gene3D G3DSA:3.40.50.620 22 520 0.0 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_08425 a4d5c3ed2617c225f1d4751c44008c9a 224 SMART SM00448 2 112 5.1E-44 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_08425 a4d5c3ed2617c225f1d4751c44008c9a 224 Gene3D G3DSA:3.40.50.2300 1 123 2.6E-40 T 11-10-2018 AFK25_08425 a4d5c3ed2617c225f1d4751c44008c9a 224 SUPERFAMILY SSF52172 3 171 7.12E-43 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_08425 a4d5c3ed2617c225f1d4751c44008c9a 224 Pfam PF00072 Response regulator receiver domain 4 112 1.5E-31 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_08425 a4d5c3ed2617c225f1d4751c44008c9a 224 Gene3D G3DSA:1.10.10.10 124 224 8.7E-31 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_08425 a4d5c3ed2617c225f1d4751c44008c9a 224 Pfam PF00486 Transcriptional regulatory protein, C terminal 145 220 4.6E-23 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFK25_08425 a4d5c3ed2617c225f1d4751c44008c9a 224 SMART SM00862 144 221 7.5E-23 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFK25_14370 fa50aa5cf6078ce8ccd5ac42ec160a5d 200 SMART SM00448 3 116 3.0E-22 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_14370 fa50aa5cf6078ce8ccd5ac42ec160a5d 200 SUPERFAMILY SSF52172 1 129 2.28E-27 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_14370 fa50aa5cf6078ce8ccd5ac42ec160a5d 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 168 180 1.3E-7 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_14370 fa50aa5cf6078ce8ccd5ac42ec160a5d 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 152 168 1.3E-7 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_14370 fa50aa5cf6078ce8ccd5ac42ec160a5d 200 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 138 152 1.3E-7 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_14370 fa50aa5cf6078ce8ccd5ac42ec160a5d 200 SMART SM00421 135 192 7.1E-13 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_14370 fa50aa5cf6078ce8ccd5ac42ec160a5d 200 Gene3D G3DSA:3.40.50.12740 3 198 3.6E-51 T 11-10-2018 AFK25_14370 fa50aa5cf6078ce8ccd5ac42ec160a5d 200 Pfam PF00196 Bacterial regulatory proteins, luxR family 137 192 2.4E-15 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_14370 fa50aa5cf6078ce8ccd5ac42ec160a5d 200 Pfam PF00072 Response regulator receiver domain 5 116 1.0E-21 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_14370 fa50aa5cf6078ce8ccd5ac42ec160a5d 200 SUPERFAMILY SSF46894 132 198 7.14E-17 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFK25_08940 086910082124481fb787016435e4cff4 237 TIGRFAM TIGR01934 MenG_MenH_UbiE: ubiquinone/menaquinone biosynthesis methyltransferase 9 233 1.0E-81 T 11-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 AFK25_08940 086910082124481fb787016435e4cff4 237 SUPERFAMILY SSF53335 3 233 3.8E-53 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_08940 086910082124481fb787016435e4cff4 237 ProSitePatterns PS01183 ubiE/COQ5 methyltransferase family signature 1. 20 35 - T 11-10-2018 IPR023576 UbiE/COQ5 methyltransferase, conserved site GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 AFK25_08940 086910082124481fb787016435e4cff4 237 Pfam PF01209 ubiE/COQ5 methyltransferase family 1 233 1.8E-101 T 11-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 AFK25_08940 086910082124481fb787016435e4cff4 237 Gene3D G3DSA:3.40.50.150 15 234 8.5E-69 T 11-10-2018 AFK25_08940 086910082124481fb787016435e4cff4 237 TIGRFAM TIGR02752 MenG_heptapren: demethylmenaquinone methyltransferase 3 233 7.8E-139 T 11-10-2018 IPR014122 Demethylmenaquinone methyltransferase GO:0008168|GO:0009234 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 AFK25_08940 086910082124481fb787016435e4cff4 237 Hamap MF_01813 Ubiquinone/menaquinone biosynthesis C-methyltransferase UbiE [ubiE]. 1 233 36.832 T 11-10-2018 IPR004033 UbiE/COQ5 methyltransferase GO:0008168 KEGG: 00130+2.1.1.163|MetaCyc: PWY-5839|MetaCyc: PWY-5844|MetaCyc: PWY-5849|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895|Reactome: R-HSA-2142789 AFK25_07315 78ddf35e035ec0a440321a419d5bd90e 220 Pfam PF13419 Haloacid dehalogenase-like hydrolase 7 191 5.5E-16 T 11-10-2018 AFK25_07315 78ddf35e035ec0a440321a419d5bd90e 220 SUPERFAMILY SSF56784 2 215 4.87E-49 T 11-10-2018 IPR036412 HAD-like superfamily AFK25_07315 78ddf35e035ec0a440321a419d5bd90e 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 135 151 1.1E-27 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFK25_07315 78ddf35e035ec0a440321a419d5bd90e 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 153 173 1.1E-27 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFK25_07315 78ddf35e035ec0a440321a419d5bd90e 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 3 14 1.1E-27 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFK25_07315 78ddf35e035ec0a440321a419d5bd90e 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 43 56 1.1E-27 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFK25_07315 78ddf35e035ec0a440321a419d5bd90e 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 180 193 1.1E-27 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFK25_07315 78ddf35e035ec0a440321a419d5bd90e 220 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 29 42 1.1E-27 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFK25_07315 78ddf35e035ec0a440321a419d5bd90e 220 TIGRFAM TIGR01493 HAD-SF-IA-v2: HAD hydrolase, family IA, variant 2 5 184 4.9E-26 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFK25_07315 78ddf35e035ec0a440321a419d5bd90e 220 Gene3D G3DSA:1.10.150.240 17 91 1.5E-69 T 11-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 AFK25_07315 78ddf35e035ec0a440321a419d5bd90e 220 Gene3D G3DSA:3.40.50.1000 7 215 1.5E-69 T 11-10-2018 IPR023214 HAD superfamily AFK25_07315 78ddf35e035ec0a440321a419d5bd90e 220 TIGRFAM TIGR01428 HAD_type_II: haloacid dehalogenase, type II 4 196 2.9E-59 T 11-10-2018 IPR006328 L-2-Haloacid dehalogenase GO:0019120 KEGG: 00361+3.8.1.2|KEGG: 00625+3.8.1.2|MetaCyc: PWY-7425 AFK25_07315 78ddf35e035ec0a440321a419d5bd90e 220 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 63 185 1.3E-8 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFK25_01085 14302835db8d7b16e23da9785113ad80 120 Hamap MF_00101 Holo-[acyl-carrier-protein] synthase [acpS]. 3 117 26.047 T 11-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 AFK25_01085 14302835db8d7b16e23da9785113ad80 120 SUPERFAMILY SSF56214 1 116 1.83E-36 T 11-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 AFK25_01085 14302835db8d7b16e23da9785113ad80 120 Gene3D G3DSA:3.90.470.20 1 120 1.4E-42 T 11-10-2018 IPR037143 4'-phosphopantetheinyl transferase domain superfamily GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 AFK25_01085 14302835db8d7b16e23da9785113ad80 120 Pfam PF01648 4'-phosphopantetheinyl transferase superfamily 4 111 3.7E-25 T 11-10-2018 IPR008278 4'-phosphopantetheinyl transferase domain GO:0000287|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289|Reactome: R-HSA-199220 AFK25_01085 14302835db8d7b16e23da9785113ad80 120 ProDom PD004282 TRANSFERASE SYNTHASE HOLO-ACYL-CARRIER-PROTEIN HOLO-ACP 4'-PHOSPHOPANTETHEINYL FATTY ACID METAL-BINDING MAGNESIUM LIPID 8 118 1.0E-33 T 11-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 AFK25_01085 14302835db8d7b16e23da9785113ad80 120 TIGRFAM TIGR00516 acpS: holo-[acyl-carrier-protein] synthase 1 119 8.6E-41 T 11-10-2018 IPR002582 Holo-[acyl carrier protein] synthase GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 AFK25_01085 14302835db8d7b16e23da9785113ad80 120 TIGRFAM TIGR00556 pantethn_trn: phosphopantetheine--protein transferase domain 1 117 1.4E-32 T 11-10-2018 IPR004568 Phosphopantetheine-protein transferase domain GO:0000287|GO:0006633|GO:0008897 KEGG: 00770+2.7.8.7|MetaCyc: PWY-6012|MetaCyc: PWY-6012-1|MetaCyc: PWY-6289 AFK25_08890 08ea580b871454c02906a839badcd2b0 211 Gene3D G3DSA:3.20.20.70 2 211 8.0E-53 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_08890 08ea580b871454c02906a839badcd2b0 211 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 2 211 32.121 T 11-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 AFK25_08890 08ea580b871454c02906a839badcd2b0 211 SUPERFAMILY SSF51366 3 208 1.54E-42 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFK25_08890 08ea580b871454c02906a839badcd2b0 211 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 5 206 5.1E-41 T 11-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 AFK25_00710 0d229390f9786102d6f5ba70782541bb 216 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 3.9E-82 T 11-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 AFK25_00710 0d229390f9786102d6f5ba70782541bb 216 Gene3D G3DSA:3.40.50.300 1 214 6.2E-85 T 11-10-2018 AFK25_00710 0d229390f9786102d6f5ba70782541bb 216 Pfam PF00406 Adenylate kinase 5 190 3.2E-62 T 11-10-2018 AFK25_00710 0d229390f9786102d6f5ba70782541bb 216 Hamap MF_00235 Adenylate kinase [adk]. 1 213 53.921 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFK25_00710 0d229390f9786102d6f5ba70782541bb 216 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 11-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFK25_00710 0d229390f9786102d6f5ba70782541bb 216 SUPERFAMILY SSF52540 1 214 1.04E-46 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_00710 0d229390f9786102d6f5ba70782541bb 216 PRINTS PR00094 Adenylate kinase signature 4 17 7.2E-33 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFK25_00710 0d229390f9786102d6f5ba70782541bb 216 PRINTS PR00094 Adenylate kinase signature 177 191 7.2E-33 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFK25_00710 0d229390f9786102d6f5ba70782541bb 216 PRINTS PR00094 Adenylate kinase signature 32 46 7.2E-33 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFK25_00710 0d229390f9786102d6f5ba70782541bb 216 PRINTS PR00094 Adenylate kinase signature 81 97 7.2E-33 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFK25_00710 0d229390f9786102d6f5ba70782541bb 216 PRINTS PR00094 Adenylate kinase signature 160 175 7.2E-33 T 11-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AFK25_00710 0d229390f9786102d6f5ba70782541bb 216 Pfam PF05191 Adenylate kinase, active site lid 127 162 2.1E-18 T 11-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 AFK25_04800 3fff4de5f573a95648300e5e15ae6ecb 404 Gene3D G3DSA:1.20.5.170 245 289 8.4E-25 T 11-10-2018 AFK25_04800 3fff4de5f573a95648300e5e15ae6ecb 404 Gene3D G3DSA:3.20.20.450 1 228 2.2E-66 T 11-10-2018 IPR035919 EAL domain superfamily AFK25_04800 3fff4de5f573a95648300e5e15ae6ecb 404 Pfam PF10388 EAL-domain associated signalling protein domain 243 403 5.4E-78 T 11-10-2018 IPR018842 YkuI, C-terminal AFK25_04800 3fff4de5f573a95648300e5e15ae6ecb 404 Pfam PF00563 EAL domain 10 235 6.7E-30 T 11-10-2018 IPR001633 EAL domain AFK25_04800 3fff4de5f573a95648300e5e15ae6ecb 404 SMART SM00052 2 240 7.5E-29 T 11-10-2018 IPR001633 EAL domain AFK25_04800 3fff4de5f573a95648300e5e15ae6ecb 404 Gene3D G3DSA:3.30.450.20 290 404 6.2E-47 T 11-10-2018 AFK25_04800 3fff4de5f573a95648300e5e15ae6ecb 404 SUPERFAMILY SSF103190 262 400 7.06E-42 T 11-10-2018 IPR029151 Periplasmic sensor-like domain superfamily AFK25_04800 3fff4de5f573a95648300e5e15ae6ecb 404 SUPERFAMILY SSF141868 4 258 1.31E-47 T 11-10-2018 IPR035919 EAL domain superfamily AFK25_11520 7be84c93d06d6a1f7ba21a552660f1fe 66 ProSitePatterns PS00936 Ribosomal protein L35 signature. 5 31 - T 11-10-2018 IPR018265 Ribosomal protein L35, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_11520 7be84c93d06d6a1f7ba21a552660f1fe 66 PRINTS PR00064 Ribosomal protein L35 signature 36 54 9.9E-22 T 11-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AFK25_11520 7be84c93d06d6a1f7ba21a552660f1fe 66 PRINTS PR00064 Ribosomal protein L35 signature 3 20 9.9E-22 T 11-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AFK25_11520 7be84c93d06d6a1f7ba21a552660f1fe 66 PRINTS PR00064 Ribosomal protein L35 signature 21 35 9.9E-22 T 11-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AFK25_11520 7be84c93d06d6a1f7ba21a552660f1fe 66 TIGRFAM TIGR00001 rpmI_bact: ribosomal protein bL35 2 62 6.9E-26 T 11-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AFK25_11520 7be84c93d06d6a1f7ba21a552660f1fe 66 Gene3D G3DSA:2.40.50.530 1 63 6.0E-22 T 11-10-2018 AFK25_11520 7be84c93d06d6a1f7ba21a552660f1fe 66 Hamap MF_00514 50S ribosomal protein L35 [rpmI]. 1 64 18.774 T 11-10-2018 IPR001706 Ribosomal protein L35, non-mitochondrial GO:0003735|GO:0005840|GO:0006412 AFK25_11520 7be84c93d06d6a1f7ba21a552660f1fe 66 Pfam PF01632 Ribosomal protein L35 2 62 1.3E-24 T 11-10-2018 IPR021137 Ribosomal protein L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_11520 7be84c93d06d6a1f7ba21a552660f1fe 66 SUPERFAMILY SSF143034 2 62 9.03E-22 T 11-10-2018 IPR037229 Ribosomal protein L35 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00790 fa791287799ea37f3698c02e9722f434 335 SUPERFAMILY SSF117916 1 80 6.21E-8 T 11-10-2018 IPR034904 Fe-S cluster assembly domain superfamily AFK25_00790 fa791287799ea37f3698c02e9722f434 335 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 95 330 2.1E-85 T 11-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 AFK25_00790 fa791287799ea37f3698c02e9722f434 335 Pfam PF01883 Iron-sulfur cluster assembly protein 5 53 1.3E-6 T 11-10-2018 IPR002744 MIP18 family-like AFK25_00790 fa791287799ea37f3698c02e9722f434 335 Gene3D G3DSA:3.30.300.130 1 88 3.8E-6 T 11-10-2018 IPR034904 Fe-S cluster assembly domain superfamily AFK25_00790 fa791287799ea37f3698c02e9722f434 335 ProSitePatterns PS01215 Mrp family signature. 196 212 - T 11-10-2018 IPR000808 Mrp, conserved site GO:0005524 AFK25_00790 fa791287799ea37f3698c02e9722f434 335 SUPERFAMILY SSF52540 80 298 3.17E-47 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_00790 fa791287799ea37f3698c02e9722f434 335 Gene3D G3DSA:3.40.50.300 89 304 1.3E-66 T 11-10-2018 AFK25_00790 fa791287799ea37f3698c02e9722f434 335 Hamap MF_02040 Iron-sulfur cluster carrier protein. 86 331 33.983 T 11-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein AFK25_01715 ff380787832fd96222febe5409a39d6f 165 SUPERFAMILY SSF75615 106 162 3.66E-15 T 11-10-2018 AFK25_01715 ff380787832fd96222febe5409a39d6f 165 Pfam PF14824 Sirohaem biosynthesis protein central 116 143 2.3E-12 T 11-10-2018 IPR028281 Siroheme synthase, central domain KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFK25_01715 ff380787832fd96222febe5409a39d6f 165 Pfam PF13241 Putative NAD(P)-binding 4 112 8.7E-25 T 11-10-2018 AFK25_01715 ff380787832fd96222febe5409a39d6f 165 Gene3D G3DSA:3.40.50.720 1 127 1.0E-37 T 11-10-2018 AFK25_01715 ff380787832fd96222febe5409a39d6f 165 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 2 158 1.3E-33 T 11-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFK25_01715 ff380787832fd96222febe5409a39d6f 165 SUPERFAMILY SSF51735 1 103 8.83E-21 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_01715 ff380787832fd96222febe5409a39d6f 165 Gene3D G3DSA:1.10.8.610 128 165 5.0E-9 T 11-10-2018 AFK25_11885 ba209159406d634cafba17520b546a5b 718 SMART SM00842 5 202 8.6E-47 T 11-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 AFK25_11885 ba209159406d634cafba17520b546a5b 718 Gene3D G3DSA:3.30.420.40 8 202 3.3E-38 T 11-10-2018 AFK25_11885 ba209159406d634cafba17520b546a5b 718 Gene3D G3DSA:3.90.640.10 241 298 3.3E-38 T 11-10-2018 AFK25_11885 ba209159406d634cafba17520b546a5b 718 SUPERFAMILY SSF53067 209 382 9.36E-32 T 11-10-2018 AFK25_11885 ba209159406d634cafba17520b546a5b 718 Gene3D G3DSA:3.30.1490.110 80 175 3.3E-38 T 11-10-2018 AFK25_11885 ba209159406d634cafba17520b546a5b 718 SUPERFAMILY SSF53067 4 198 3.8E-23 T 11-10-2018 AFK25_11885 ba209159406d634cafba17520b546a5b 718 Gene3D G3DSA:3.30.420.40 203 349 3.3E-38 T 11-10-2018 AFK25_11885 ba209159406d634cafba17520b546a5b 718 Pfam PF14450 Cell division protein FtsA 213 376 4.7E-10 T 11-10-2018 AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 PRINTS PR00315 GTP-binding elongation factor signature 15 28 3.8E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 PRINTS PR00315 GTP-binding elongation factor signature 135 144 3.8E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 PRINTS PR00315 GTP-binding elongation factor signature 83 93 3.8E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 PRINTS PR00315 GTP-binding elongation factor signature 99 110 3.8E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.8E-14 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 SUPERFAMILY SSF50447 195 289 5.55E-23 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 Gene3D G3DSA:3.40.50.300 9 194 5.0E-75 T 11-10-2018 AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 Gene3D G3DSA:3.30.70.2570 489 563 3.4E-36 T 11-10-2018 IPR038363 LepA, C-terminal domain superfamily AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 Hamap MF_00071 Elongation factor 4 [lepA]. 1 607 320.414 T 11-10-2018 IPR006297 Elongation factor 4 GO:0005525 AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 Pfam PF00009 Elongation factor Tu GTP binding domain 12 190 3.1E-54 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 Gene3D G3DSA:3.30.70.870 295 376 4.6E-37 T 11-10-2018 AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 SUPERFAMILY SSF54980 301 379 6.83E-20 T 11-10-2018 IPR035647 EF-G domain III/V-like AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 SUPERFAMILY SSF52540 6 226 1.49E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 TIGRFAM TIGR01393 lepA: elongation factor 4 12 605 0.0 T 11-10-2018 IPR006297 Elongation factor 4 GO:0005525 AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 Gene3D G3DSA:2.40.30.10 195 294 2.6E-38 T 11-10-2018 AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 Pfam PF06421 GTP-binding protein LepA C-terminus 497 603 6.8E-53 T 11-10-2018 IPR013842 GTP-binding protein LepA, C-terminal AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 Gene3D G3DSA:3.30.70.3380 377 488 1.9E-44 T 11-10-2018 AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 Pfam PF03144 Elongation factor Tu domain 2 214 284 6.6E-12 T 11-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 SMART SM00838 410 495 6.5E-4 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 SUPERFAMILY SSF54980 408 503 3.12E-27 T 11-10-2018 IPR035647 EF-G domain III/V-like AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 Pfam PF00679 Elongation factor G C-terminus 408 495 2.1E-25 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like AFK25_10400 2d0a985c5542bb6467f3ebecbea2e07b 608 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 183 5.6E-19 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFK25_12655 aadb541755212bde843b54ffb046735d 146 Pfam PF01934 Protein of unknown function DUF86 12 125 1.8E-21 T 11-10-2018 IPR008201 Protein of unknown function DUF86 AFK25_12655 aadb541755212bde843b54ffb046735d 146 Gene3D G3DSA:1.20.120.580 1 142 3.2E-55 T 11-10-2018 IPR037038 Bsu32300-like superfamily AFK25_11700 39e2b057eaa996669f14c67ea282798b 364 SUPERFAMILY SSF55920 137 364 9.29E-80 T 11-10-2018 IPR036005 Creatinase/aminopeptidase-like AFK25_11700 39e2b057eaa996669f14c67ea282798b 364 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 294 306 - T 11-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site AFK25_11700 39e2b057eaa996669f14c67ea282798b 364 Gene3D G3DSA:3.90.230.10 138 362 1.3E-81 T 11-10-2018 AFK25_11700 39e2b057eaa996669f14c67ea282798b 364 Pfam PF00557 Metallopeptidase family M24 147 348 2.5E-66 T 11-10-2018 IPR000994 Peptidase M24 AFK25_11700 39e2b057eaa996669f14c67ea282798b 364 Gene3D G3DSA:3.40.350.10 2 137 2.4E-40 T 11-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal AFK25_11700 39e2b057eaa996669f14c67ea282798b 364 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 137 6.2E-27 T 11-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 AFK25_11700 39e2b057eaa996669f14c67ea282798b 364 SUPERFAMILY SSF53092 1 136 1.16E-35 T 11-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal AFK25_11700 39e2b057eaa996669f14c67ea282798b 364 PRINTS PR00599 Methionine aminopeptidase-1 signature 218 234 2.1E-8 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFK25_11700 39e2b057eaa996669f14c67ea282798b 364 PRINTS PR00599 Methionine aminopeptidase-1 signature 316 328 2.1E-8 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFK25_11700 39e2b057eaa996669f14c67ea282798b 364 PRINTS PR00599 Methionine aminopeptidase-1 signature 196 209 2.1E-8 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFK25_13250 9778c38092955e6de9cda86d08de0008 159 Gene3D G3DSA:1.20.58.300 2 131 7.2E-12 T 11-10-2018 AFK25_13250 9778c38092955e6de9cda86d08de0008 159 SUPERFAMILY SSF140566 3 131 5.75E-20 T 11-10-2018 IPR036679 FlgN-like superfamily GO:0005515|GO:0044780 AFK25_13250 9778c38092955e6de9cda86d08de0008 159 Pfam PF05130 FlgN protein 3 141 6.2E-26 T 11-10-2018 IPR007809 FlgN-like protein GO:0005515|GO:0044780 AFK25_08325 eaed07dffcdda09d1b70dc5368188179 484 Gene3D G3DSA:1.10.1060.10 6 152 6.3E-20 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFK25_08325 eaed07dffcdda09d1b70dc5368188179 484 TIGRFAM TIGR01317 GOGAT_sm_gam: glutamate synthase, NADH/NADPH, small subunit 3 483 3.7E-233 T 11-10-2018 IPR006005 Glutamate synthase, NADH/NADPH, small subunit 1 GO:0006537|GO:0016639|GO:0055114 AFK25_08325 eaed07dffcdda09d1b70dc5368188179 484 Pfam PF14691 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster 24 140 1.9E-21 T 11-10-2018 IPR028261 Dihydroprymidine dehydrogenase domain II Reactome: R-HSA-73621 AFK25_08325 eaed07dffcdda09d1b70dc5368188179 484 SUPERFAMILY SSF46548 2 163 8.89E-36 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFK25_08325 eaed07dffcdda09d1b70dc5368188179 484 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 153 472 8.3E-27 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFK25_08325 eaed07dffcdda09d1b70dc5368188179 484 PRINTS PR00419 Adrenodoxin reductase family signature 219 229 8.5E-25 T 11-10-2018 AFK25_08325 eaed07dffcdda09d1b70dc5368188179 484 PRINTS PR00419 Adrenodoxin reductase family signature 154 176 8.5E-25 T 11-10-2018 AFK25_08325 eaed07dffcdda09d1b70dc5368188179 484 PRINTS PR00419 Adrenodoxin reductase family signature 177 190 8.5E-25 T 11-10-2018 AFK25_08325 eaed07dffcdda09d1b70dc5368188179 484 PRINTS PR00419 Adrenodoxin reductase family signature 294 308 8.5E-25 T 11-10-2018 AFK25_08325 eaed07dffcdda09d1b70dc5368188179 484 Gene3D G3DSA:3.50.50.60 153 287 1.6E-35 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_08325 eaed07dffcdda09d1b70dc5368188179 484 Gene3D G3DSA:3.50.50.60 288 484 3.0E-13 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_08325 eaed07dffcdda09d1b70dc5368188179 484 SUPERFAMILY SSF51971 151 420 2.06E-63 T 11-10-2018 AFK25_10790 3dce793fcde532f09dfe51dd8fe5c24c 748 PRINTS PR01755 Bacterial translocase SecF protein signature 475 490 4.4E-22 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFK25_10790 3dce793fcde532f09dfe51dd8fe5c24c 748 PRINTS PR01755 Bacterial translocase SecF protein signature 633 651 4.4E-22 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFK25_10790 3dce793fcde532f09dfe51dd8fe5c24c 748 PRINTS PR01755 Bacterial translocase SecF protein signature 668 683 4.4E-22 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFK25_10790 3dce793fcde532f09dfe51dd8fe5c24c 748 PRINTS PR01755 Bacterial translocase SecF protein signature 585 599 4.4E-22 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFK25_10790 3dce793fcde532f09dfe51dd8fe5c24c 748 TIGRFAM TIGR00966 3a0501s07: protein-export membrane protein SecF 477 720 5.6E-68 T 11-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 AFK25_10790 3dce793fcde532f09dfe51dd8fe5c24c 748 Hamap MF_01464_B Protein-export membrane protein SecF [secF]. 448 731 25.695 T 11-10-2018 IPR005665 Protein-export membrane protein SecF, bacterial GO:0006886|GO:0015450 AFK25_10790 3dce793fcde532f09dfe51dd8fe5c24c 748 Gene3D G3DSA:3.30.70.3400 34 123 3.4E-22 T 11-10-2018 AFK25_10790 3dce793fcde532f09dfe51dd8fe5c24c 748 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 187 399 1.3E-52 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFK25_10790 3dce793fcde532f09dfe51dd8fe5c24c 748 TIGRFAM TIGR00916 2A0604s01: protein-export membrane protein, SecD/SecF family 532 717 5.0E-49 T 11-10-2018 IPR022645 Protein-export membrane protein SecD/SecF, bacterial AFK25_10790 3dce793fcde532f09dfe51dd8fe5c24c 748 Gene3D G3DSA:1.20.1640.10 426 473 1.0E-12 T 11-10-2018 AFK25_10790 3dce793fcde532f09dfe51dd8fe5c24c 748 SUPERFAMILY SSF82866 555 733 6.41E-36 T 11-10-2018 AFK25_10790 3dce793fcde532f09dfe51dd8fe5c24c 748 Gene3D G3DSA:1.20.1640.10 554 747 3.2E-10 T 11-10-2018 AFK25_10790 3dce793fcde532f09dfe51dd8fe5c24c 748 TIGRFAM TIGR01129 secD: protein-export membrane protein SecD 34 406 1.6E-108 T 11-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 AFK25_10790 3dce793fcde532f09dfe51dd8fe5c24c 748 Pfam PF07549 SecD/SecF GG Motif 471 496 2.0E-5 T 11-10-2018 IPR022646 Protein-export membrane protein SecD/SecF/SecDF, conserved site AFK25_10790 3dce793fcde532f09dfe51dd8fe5c24c 748 Hamap MF_01463_B Protein translocase subunit SecD [secD]. 1 421 33.063 T 11-10-2018 IPR005791 Protein translocase subunit SecD GO:0006886|GO:0015450 AFK25_10790 3dce793fcde532f09dfe51dd8fe5c24c 748 Gene3D G3DSA:3.30.70.1320 222 246 1.0E-12 T 11-10-2018 AFK25_10790 3dce793fcde532f09dfe51dd8fe5c24c 748 Gene3D G3DSA:1.20.1640.10 250 425 1.0E-12 T 11-10-2018 AFK25_10790 3dce793fcde532f09dfe51dd8fe5c24c 748 SUPERFAMILY SSF82866 216 411 5.75E-39 T 11-10-2018 AFK25_10790 3dce793fcde532f09dfe51dd8fe5c24c 748 Pfam PF02355 Protein export membrane protein 240 403 1.7E-11 T 11-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial AFK25_10790 3dce793fcde532f09dfe51dd8fe5c24c 748 Pfam PF02355 Protein export membrane protein 553 729 3.8E-63 T 11-10-2018 IPR022813 Protein-export membrane protein SecD/SecF, archaeal and bacterial AFK25_09920 d988b966070a2676b5775e20bf4ae28c 148 PIRSF PIRSF001399 1 146 4.2E-61 T 11-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFK25_09920 d988b966070a2676b5775e20bf4ae28c 148 Hamap MF_00169 3-dehydroquinate dehydratase [aroQ]. 1 148 67.416 T 11-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFK25_09920 d988b966070a2676b5775e20bf4ae28c 148 SUPERFAMILY SSF52304 3 145 6.54E-60 T 11-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFK25_09920 d988b966070a2676b5775e20bf4ae28c 148 TIGRFAM TIGR01088 aroQ: 3-dehydroquinate dehydratase, type II 4 142 1.7E-63 T 11-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFK25_09920 d988b966070a2676b5775e20bf4ae28c 148 Pfam PF01220 Dehydroquinase class II 4 139 8.1E-61 T 11-10-2018 IPR001874 Dehydroquinase, class II GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFK25_09920 d988b966070a2676b5775e20bf4ae28c 148 Gene3D G3DSA:3.40.50.9100 1 146 4.0E-65 T 11-10-2018 IPR036441 Dehydroquinase, class II superfamily GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFK25_09920 d988b966070a2676b5775e20bf4ae28c 148 ProDom PD004527 LYASE II 3-DEHYDROQUINATE BIOSYNTHESIS DEHYDRATASE TYPE 3-DEHYDROQUINASE DHQASE AMINO AROMATIC 17 141 4.0E-43 T 11-10-2018 AFK25_09920 d988b966070a2676b5775e20bf4ae28c 148 ProSitePatterns PS01029 Dehydroquinase class II signature. 7 24 - T 11-10-2018 IPR018509 Dehydroquinase, class II, conserved site GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AFK25_04835 c1f2a27f986531c082a2dfeb21bf185a 221 Gene3D G3DSA:3.30.70.1450 139 218 2.3E-28 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFK25_04835 c1f2a27f986531c082a2dfeb21bf185a 221 Gene3D G3DSA:3.40.50.720 1 138 5.0E-40 T 11-10-2018 AFK25_04835 c1f2a27f986531c082a2dfeb21bf185a 221 Pfam PF02080 TrkA-C domain 150 217 3.6E-17 T 11-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFK25_04835 c1f2a27f986531c082a2dfeb21bf185a 221 Pfam PF02254 TrkA-N domain 6 121 1.3E-30 T 11-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AFK25_04835 c1f2a27f986531c082a2dfeb21bf185a 221 SUPERFAMILY SSF51735 5 135 2.51E-39 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_04835 c1f2a27f986531c082a2dfeb21bf185a 221 SUPERFAMILY SSF116726 132 216 1.01E-22 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFK25_09555 1bbd0e10df901a7d78cbb2e34c90adb3 345 Pfam PF00005 ABC transporter 16 159 7.4E-33 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_09555 1bbd0e10df901a7d78cbb2e34c90adb3 345 Gene3D G3DSA:3.40.50.300 2 236 9.4E-62 T 11-10-2018 AFK25_09555 1bbd0e10df901a7d78cbb2e34c90adb3 345 SMART SM00382 22 210 2.0E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_09555 1bbd0e10df901a7d78cbb2e34c90adb3 345 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_09555 1bbd0e10df901a7d78cbb2e34c90adb3 345 SUPERFAMILY SSF52540 5 242 1.58E-70 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_09815 164db846043c67df2248b18316bef0d4 280 SMART SM00363 6 71 7.6E-9 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_09815 164db846043c67df2248b18316bef0d4 280 Gene3D G3DSA:3.10.290.10 2 64 1.3E-24 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFK25_09815 164db846043c67df2248b18316bef0d4 280 Gene3D G3DSA:3.40.50.150 65 279 1.8E-83 T 11-10-2018 AFK25_09815 164db846043c67df2248b18316bef0d4 280 SUPERFAMILY SSF53335 61 245 2.74E-20 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_09815 164db846043c67df2248b18316bef0d4 280 Pfam PF01728 FtsJ-like methyltransferase 62 244 8.4E-16 T 11-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 AFK25_09815 164db846043c67df2248b18316bef0d4 280 PIRSF PIRSF005578 1 266 2.9E-103 T 11-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 AFK25_09815 164db846043c67df2248b18316bef0d4 280 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 7 239 1.1E-92 T 11-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 AFK25_09815 164db846043c67df2248b18316bef0d4 280 SUPERFAMILY SSF55174 5 71 2.5E-12 T 11-10-2018 AFK25_09815 164db846043c67df2248b18316bef0d4 280 Pfam PF01479 S4 domain 6 48 5.0E-10 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_06815 17d630a2b24ec030e5a466d50b7e1b95 380 Gene3D G3DSA:1.20.140.10 236 379 4.5E-47 T 11-10-2018 AFK25_06815 17d630a2b24ec030e5a466d50b7e1b95 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFK25_06815 17d630a2b24ec030e5a466d50b7e1b95 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 217 1.0E-26 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFK25_06815 17d630a2b24ec030e5a466d50b7e1b95 380 Gene3D G3DSA:2.40.110.10 120 235 2.6E-46 T 11-10-2018 AFK25_06815 17d630a2b24ec030e5a466d50b7e1b95 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFK25_06815 17d630a2b24ec030e5a466d50b7e1b95 380 SUPERFAMILY SSF47203 228 378 3.7E-49 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFK25_06815 17d630a2b24ec030e5a466d50b7e1b95 380 Gene3D G3DSA:1.10.540.10 3 119 2.5E-37 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFK25_06815 17d630a2b24ec030e5a466d50b7e1b95 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 378 3.1E-44 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFK25_06815 17d630a2b24ec030e5a466d50b7e1b95 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 117 1.0E-34 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFK25_06815 17d630a2b24ec030e5a466d50b7e1b95 380 SUPERFAMILY SSF56645 3 242 3.01E-90 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFK25_03285 312c42acde6db56324ecdb78617b3473 457 Gene3D G3DSA:3.40.50.300 7 191 5.4E-24 T 11-10-2018 AFK25_03285 312c42acde6db56324ecdb78617b3473 457 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 8 448 1.4E-144 T 11-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 AFK25_03285 312c42acde6db56324ecdb78617b3473 457 SUPERFAMILY SSF52540 7 199 1.15E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_03285 312c42acde6db56324ecdb78617b3473 457 Gene3D G3DSA:3.40.50.880 248 419 1.6E-9 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_03285 312c42acde6db56324ecdb78617b3473 457 Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. 6 440 45.357 T 11-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 AFK25_03285 312c42acde6db56324ecdb78617b3473 457 SUPERFAMILY SSF52317 249 455 1.97E-30 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_03285 312c42acde6db56324ecdb78617b3473 457 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 9 195 6.4E-22 T 11-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AFK25_03285 312c42acde6db56324ecdb78617b3473 457 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 250 439 1.8E-37 T 11-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 AFK25_05530 1acce012aabd2c1248a3ec14f4e83d99 1186 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1180 24.8 T 11-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 AFK25_05530 1acce012aabd2c1248a3ec14f4e83d99 1186 PIRSF PIRSF005719 1 1185 0.0 T 11-10-2018 IPR024704 Structural maintenance of chromosomes protein AFK25_05530 1acce012aabd2c1248a3ec14f4e83d99 1186 SUPERFAMILY SSF75553 484 684 1.57E-56 T 11-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 AFK25_05530 1acce012aabd2c1248a3ec14f4e83d99 1186 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 2 1178 0.0 T 11-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 AFK25_05530 1acce012aabd2c1248a3ec14f4e83d99 1186 Gene3D G3DSA:3.30.70.1620 578 667 1.4E-66 T 11-10-2018 AFK25_05530 1acce012aabd2c1248a3ec14f4e83d99 1186 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 139 2.7E-41 T 11-10-2018 IPR003395 RecF/RecN/SMC, N-terminal AFK25_05530 1acce012aabd2c1248a3ec14f4e83d99 1186 Pfam PF02463 RecF/RecN/SMC N terminal domain 729 1171 4.0E-30 T 11-10-2018 IPR003395 RecF/RecN/SMC, N-terminal AFK25_05530 1acce012aabd2c1248a3ec14f4e83d99 1186 SMART SM00968 518 637 8.2E-39 T 11-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 AFK25_05530 1acce012aabd2c1248a3ec14f4e83d99 1186 Gene3D G3DSA:1.20.1060.20 495 679 1.4E-66 T 11-10-2018 AFK25_05530 1acce012aabd2c1248a3ec14f4e83d99 1186 Gene3D G3DSA:3.40.50.300 1 259 5.7E-62 T 11-10-2018 AFK25_05530 1acce012aabd2c1248a3ec14f4e83d99 1186 Gene3D G3DSA:3.40.50.300 963 1184 6.5E-54 T 11-10-2018 AFK25_05530 1acce012aabd2c1248a3ec14f4e83d99 1186 SUPERFAMILY SSF52540 3 1173 2.07E-54 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_05530 1acce012aabd2c1248a3ec14f4e83d99 1186 Pfam PF06470 SMC proteins Flexible Hinge Domain 518 637 1.2E-28 T 11-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 AFK25_12720 aed0ebd692d7e210f8410397edda4cb6 465 SUPERFAMILY SSF101960 32 462 1.44E-141 T 11-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily AFK25_12720 aed0ebd692d7e210f8410397edda4cb6 465 TIGRFAM TIGR01980 sufB: FeS assembly protein SufB 10 456 2.4E-232 T 11-10-2018 IPR010231 SUF system FeS cluster assembly, SufB GO:0016226 AFK25_12720 aed0ebd692d7e210f8410397edda4cb6 465 Pfam PF01458 Uncharacterized protein family (UPF0051) 211 436 4.4E-75 T 11-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 AFK25_04775 b3b7f35d15f43061d3fa08c4a65e0030 696 Pfam PF02503 Polyphosphate kinase middle domain 126 329 5.9E-72 T 11-10-2018 IPR024953 Polyphosphate kinase middle domain KEGG: 00190+2.7.4.1 AFK25_04775 b3b7f35d15f43061d3fa08c4a65e0030 696 Pfam PF13090 Polyphosphate kinase C-terminal domain 338 685 4.4E-162 T 11-10-2018 IPR025200 Polyphosphate kinase C-terminal domain KEGG: 00190+2.7.4.1 AFK25_04775 b3b7f35d15f43061d3fa08c4a65e0030 696 TIGRFAM TIGR03705 poly_P_kin: polyphosphate kinase 1 10 686 1.3E-290 T 11-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 AFK25_04775 b3b7f35d15f43061d3fa08c4a65e0030 696 Pfam PF13089 Polyphosphate kinase N-terminal domain 11 117 1.4E-43 T 11-10-2018 IPR025198 Polyphosphate kinase N-terminal domain KEGG: 00190+2.7.4.1 AFK25_04775 b3b7f35d15f43061d3fa08c4a65e0030 696 SUPERFAMILY SSF143724 115 309 3.34E-63 T 11-10-2018 AFK25_04775 b3b7f35d15f43061d3fa08c4a65e0030 696 SUPERFAMILY SSF56024 324 501 3.45E-57 T 11-10-2018 AFK25_04775 b3b7f35d15f43061d3fa08c4a65e0030 696 SUPERFAMILY SSF56024 508 693 7.85E-75 T 11-10-2018 AFK25_04775 b3b7f35d15f43061d3fa08c4a65e0030 696 Gene3D G3DSA:3.30.1840.10 3 315 1.2E-116 T 11-10-2018 IPR036830 Polyphosphate kinase middle domain superfamily KEGG: 00190+2.7.4.1 AFK25_04775 b3b7f35d15f43061d3fa08c4a65e0030 696 Gene3D G3DSA:3.30.870.10 508 694 4.1E-76 T 11-10-2018 AFK25_04775 b3b7f35d15f43061d3fa08c4a65e0030 696 PIRSF PIRSF015589 1 695 1.1E-293 T 11-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 AFK25_04775 b3b7f35d15f43061d3fa08c4a65e0030 696 Gene3D G3DSA:3.30.870.10 325 507 2.0E-77 T 11-10-2018 AFK25_04775 b3b7f35d15f43061d3fa08c4a65e0030 696 SUPERFAMILY SSF140356 8 113 1.83E-42 T 11-10-2018 IPR036832 Polyphosphate kinase N-terminal domain superfamily KEGG: 00190+2.7.4.1 AFK25_04775 b3b7f35d15f43061d3fa08c4a65e0030 696 Hamap MF_00347 Polyphosphate kinase [ppk]. 8 690 30.138 T 11-10-2018 IPR003414 Polyphosphate kinase GO:0006799|GO:0008976|GO:0009358 KEGG: 00190+2.7.4.1 AFK25_11205 52d14dbf9ebaf2c98c0eb264c295a52f 170 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 2 145 9.5E-35 T 11-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 AFK25_11205 52d14dbf9ebaf2c98c0eb264c295a52f 170 Gene3D G3DSA:3.60.21.10 1 168 1.7E-48 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like AFK25_11205 52d14dbf9ebaf2c98c0eb264c295a52f 170 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 2 149 1.6E-35 T 11-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 AFK25_11205 52d14dbf9ebaf2c98c0eb264c295a52f 170 SUPERFAMILY SSF56300 3 161 1.9E-44 T 11-10-2018 AFK25_13220 33e1070435230960187e4f4054465e1c 270 PRINTS PR00207 Flagellin signature 35 52 5.7E-25 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 AFK25_13220 33e1070435230960187e4f4054465e1c 270 PRINTS PR00207 Flagellin signature 74 93 5.7E-25 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 AFK25_13220 33e1070435230960187e4f4054465e1c 270 PRINTS PR00207 Flagellin signature 109 132 5.7E-25 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 AFK25_13220 33e1070435230960187e4f4054465e1c 270 Pfam PF00700 Bacterial flagellin C-terminal helical region 184 269 1.3E-31 T 11-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 AFK25_13220 33e1070435230960187e4f4054465e1c 270 Pfam PF00669 Bacterial flagellin N-terminal helical region 3 139 1.9E-45 T 11-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 AFK25_13220 33e1070435230960187e4f4054465e1c 270 Gene3D G3DSA:1.20.1330.10 48 221 3.0E-70 T 11-10-2018 AFK25_13220 33e1070435230960187e4f4054465e1c 270 Gene3D G3DSA:1.10.8.410 222 270 6.6E-30 T 11-10-2018 AFK25_13220 33e1070435230960187e4f4054465e1c 270 SUPERFAMILY SSF64518 1 270 3.4E-98 T 11-10-2018 AFK25_00070 df083c8da5100be4fdde72eab368d25b 488 SMART SM00116 161 209 1.8E-9 T 11-10-2018 IPR000644 CBS domain AFK25_00070 df083c8da5100be4fdde72eab368d25b 488 SMART SM00116 98 148 1.5E-7 T 11-10-2018 IPR000644 CBS domain AFK25_00070 df083c8da5100be4fdde72eab368d25b 488 SUPERFAMILY SSF51412 144 485 9.29E-128 T 11-10-2018 AFK25_00070 df083c8da5100be4fdde72eab368d25b 488 TIGRFAM TIGR01302 IMP_dehydrog: inosine-5'-monophosphate dehydrogenase 10 456 8.8E-207 T 11-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 AFK25_00070 df083c8da5100be4fdde72eab368d25b 488 Hamap MF_01964 Inosine-5'-monophosphate dehydrogenase [guaB]. 10 487 87.281 T 11-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 AFK25_00070 df083c8da5100be4fdde72eab368d25b 488 PIRSF PIRSF000130 1 488 3.1E-215 T 11-10-2018 IPR005990 Inosine-5'-monophosphate dehydrogenase GO:0003938|GO:0006164|GO:0055114 KEGG: 00230+1.1.1.205|KEGG: 00983+1.1.1.205|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-7221|Reactome: R-HSA-6798695|Reactome: R-HSA-73817 AFK25_00070 df083c8da5100be4fdde72eab368d25b 488 SMART SM01240 9 474 0.0 T 11-10-2018 AFK25_00070 df083c8da5100be4fdde72eab368d25b 488 Pfam PF00571 CBS domain 153 204 1.4E-8 T 11-10-2018 IPR000644 CBS domain AFK25_00070 df083c8da5100be4fdde72eab368d25b 488 Pfam PF00571 CBS domain 97 144 6.0E-7 T 11-10-2018 IPR000644 CBS domain AFK25_00070 df083c8da5100be4fdde72eab368d25b 488 ProSitePatterns PS00487 IMP dehydrogenase / GMP reductase signature. 298 310 - T 11-10-2018 IPR015875 IMP dehydrogenase / GMP reductase, conserved site GO:0016491|GO:0055114 AFK25_00070 df083c8da5100be4fdde72eab368d25b 488 Pfam PF00478 IMP dehydrogenase / GMP reductase domain 10 474 7.6E-170 T 11-10-2018 IPR001093 IMP dehydrogenase/GMP reductase GO:0003824|GO:0055114 AFK25_00070 df083c8da5100be4fdde72eab368d25b 488 Gene3D G3DSA:3.20.20.70 1 487 4.5E-231 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_00070 df083c8da5100be4fdde72eab368d25b 488 SUPERFAMILY SSF51412 4 169 2.11E-32 T 11-10-2018 AFK25_01035 db95438d0f3a65a590bfe6f5c628e47e 515 Gene3D G3DSA:3.90.226.10 3 250 1.2E-79 T 11-10-2018 AFK25_01035 db95438d0f3a65a590bfe6f5c628e47e 515 SUPERFAMILY SSF52096 217 495 3.46E-83 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFK25_01035 db95438d0f3a65a590bfe6f5c628e47e 515 Pfam PF01039 Carboxyl transferase domain 32 512 1.3E-162 T 11-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 AFK25_01035 db95438d0f3a65a590bfe6f5c628e47e 515 SUPERFAMILY SSF52096 7 255 8.68E-68 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFK25_01035 db95438d0f3a65a590bfe6f5c628e47e 515 Gene3D G3DSA:3.90.226.10 251 514 1.2E-85 T 11-10-2018 AFK25_09040 1d5e3d8fc5f50542f41836119f3d00e0 277 SUPERFAMILY SSF47090 23 90 7.53E-20 T 11-10-2018 IPR036365 PGBD-like superfamily AFK25_09040 1d5e3d8fc5f50542f41836119f3d00e0 277 Gene3D G3DSA:1.10.10.2520 162 241 3.1E-32 T 11-10-2018 AFK25_09040 1d5e3d8fc5f50542f41836119f3d00e0 277 Gene3D G3DSA:2.40.10.420 242 277 2.0E-21 T 11-10-2018 AFK25_09040 1d5e3d8fc5f50542f41836119f3d00e0 277 Gene3D G3DSA:1.10.101.10 18 99 2.4E-20 T 11-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 AFK25_09040 1d5e3d8fc5f50542f41836119f3d00e0 277 Pfam PF07486 Cell Wall Hydrolase 178 276 6.8E-28 T 11-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 AFK25_09040 1d5e3d8fc5f50542f41836119f3d00e0 277 TIGRFAM TIGR02869 spore_SleB: spore cortex-lytic enzyme 22 277 8.1E-99 T 11-10-2018 IPR014224 Spore cortex-lytic enzyme SleB GO:0003824|GO:0009847 AFK25_09040 1d5e3d8fc5f50542f41836119f3d00e0 277 Pfam PF01471 Putative peptidoglycan binding domain 34 89 8.9E-16 T 11-10-2018 IPR002477 Peptidoglycan binding-like AFK25_03385 472c78b75815f93eb97de4c85b90dced 355 PRINTS PR00096 Glutamine amidotransferase superfamily signature 207 216 4.2E-10 T 11-10-2018 AFK25_03385 472c78b75815f93eb97de4c85b90dced 355 PRINTS PR00096 Glutamine amidotransferase superfamily signature 234 245 4.2E-10 T 11-10-2018 AFK25_03385 472c78b75815f93eb97de4c85b90dced 355 PRINTS PR00096 Glutamine amidotransferase superfamily signature 320 333 4.2E-10 T 11-10-2018 AFK25_03385 472c78b75815f93eb97de4c85b90dced 355 PRINTS PR00097 Anthranilate synthase component II signature 320 333 2.4E-5 T 11-10-2018 AFK25_03385 472c78b75815f93eb97de4c85b90dced 355 PRINTS PR00097 Anthranilate synthase component II signature 234 245 2.4E-5 T 11-10-2018 AFK25_03385 472c78b75815f93eb97de4c85b90dced 355 PRINTS PR00097 Anthranilate synthase component II signature 207 216 2.4E-5 T 11-10-2018 AFK25_03385 472c78b75815f93eb97de4c85b90dced 355 Gene3D G3DSA:3.50.30.20 1 146 1.2E-51 T 11-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_03385 472c78b75815f93eb97de4c85b90dced 355 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 131 4.0E-47 T 11-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_03385 472c78b75815f93eb97de4c85b90dced 355 SUPERFAMILY SSF52317 142 348 2.29E-55 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_03385 472c78b75815f93eb97de4c85b90dced 355 SMART SM01097 1 132 5.3E-68 T 11-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_03385 472c78b75815f93eb97de4c85b90dced 355 Gene3D G3DSA:3.40.50.880 152 354 1.1E-34 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_03385 472c78b75815f93eb97de4c85b90dced 355 Pfam PF00117 Glutamine amidotransferase class-I 167 343 1.7E-44 T 11-10-2018 IPR017926 Glutamine amidotransferase AFK25_03385 472c78b75815f93eb97de4c85b90dced 355 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 349 43.443 T 11-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_03385 472c78b75815f93eb97de4c85b90dced 355 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 3 346 1.6E-132 T 11-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_03385 472c78b75815f93eb97de4c85b90dced 355 SUPERFAMILY SSF52021 1 138 1.7E-48 T 11-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_03385 472c78b75815f93eb97de4c85b90dced 355 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 276 287 7.6E-31 T 11-10-2018 AFK25_03385 472c78b75815f93eb97de4c85b90dced 355 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 234 250 7.6E-31 T 11-10-2018 AFK25_03385 472c78b75815f93eb97de4c85b90dced 355 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 251 268 7.6E-31 T 11-10-2018 AFK25_03385 472c78b75815f93eb97de4c85b90dced 355 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 204 218 7.6E-31 T 11-10-2018 AFK25_03385 472c78b75815f93eb97de4c85b90dced 355 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 165 179 7.6E-31 T 11-10-2018 AFK25_09735 889666fb439cbae2af4af63d9e18f00f 729 Gene3D G3DSA:3.20.20.240 39 555 1.9E-245 T 11-10-2018 AFK25_09735 889666fb439cbae2af4af63d9e18f00f 729 Gene3D G3DSA:3.40.50.280 559 721 1.1E-56 T 11-10-2018 AFK25_09735 889666fb439cbae2af4af63d9e18f00f 729 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 592 720 7.1E-64 T 11-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFK25_09735 889666fb439cbae2af4af63d9e18f00f 729 Pfam PF01642 Methylmalonyl-CoA mutase 40 553 1.1E-243 T 11-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFK25_09735 889666fb439cbae2af4af63d9e18f00f 729 SUPERFAMILY SSF52242 559 722 1.03E-61 T 11-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFK25_09735 889666fb439cbae2af4af63d9e18f00f 729 Pfam PF02310 B12 binding domain 595 705 5.4E-18 T 11-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFK25_09735 889666fb439cbae2af4af63d9e18f00f 729 SUPERFAMILY SSF51703 17 555 3.92E-228 T 11-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFK25_09735 889666fb439cbae2af4af63d9e18f00f 729 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 39 559 2.1E-276 T 11-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFK25_08180 2902ecf6a25a8e3bce31d7e755323ba7 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 168 187 1.1E-5 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_08180 2902ecf6a25a8e3bce31d7e755323ba7 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 95 106 1.1E-5 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_08180 2902ecf6a25a8e3bce31d7e755323ba7 258 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 156 1.1E-5 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_08180 2902ecf6a25a8e3bce31d7e755323ba7 258 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 13 255 1.4E-45 T 11-10-2018 AFK25_08180 2902ecf6a25a8e3bce31d7e755323ba7 258 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 155 183 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFK25_08180 2902ecf6a25a8e3bce31d7e755323ba7 258 Gene3D G3DSA:3.40.50.720 2 257 1.7E-65 T 11-10-2018 AFK25_08180 2902ecf6a25a8e3bce31d7e755323ba7 258 SUPERFAMILY SSF51735 5 256 6.08E-68 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_08180 2902ecf6a25a8e3bce31d7e755323ba7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 142 158 1.9E-26 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_08180 2902ecf6a25a8e3bce31d7e755323ba7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 219 239 1.9E-26 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_08180 2902ecf6a25a8e3bce31d7e755323ba7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 8 25 1.9E-26 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_08180 2902ecf6a25a8e3bce31d7e755323ba7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 168 187 1.9E-26 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_08180 2902ecf6a25a8e3bce31d7e755323ba7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 189 206 1.9E-26 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_08180 2902ecf6a25a8e3bce31d7e755323ba7 258 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 95 106 1.9E-26 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_11855 35d87e07c3a0a7ac69ff70c80174cad7 572 Gene3D G3DSA:3.30.300.30 458 571 2.2E-28 T 11-10-2018 AFK25_11855 35d87e07c3a0a7ac69ff70c80174cad7 572 SUPERFAMILY SSF56801 15 562 3.66E-166 T 11-10-2018 AFK25_11855 35d87e07c3a0a7ac69ff70c80174cad7 572 Gene3D G3DSA:3.40.50.12780 15 455 3.5E-122 T 11-10-2018 AFK25_11855 35d87e07c3a0a7ac69ff70c80174cad7 572 Pfam PF00501 AMP-binding enzyme 50 461 2.5E-95 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFK25_11855 35d87e07c3a0a7ac69ff70c80174cad7 572 Pfam PF13193 AMP-binding enzyme C-terminal domain 471 549 1.0E-25 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFK25_11855 35d87e07c3a0a7ac69ff70c80174cad7 572 ProSitePatterns PS00455 Putative AMP-binding domain signature. 211 222 - T 11-10-2018 IPR020845 AMP-binding, conserved site AFK25_02965 92fb5213e1644bae07e605f045427a91 516 Gene3D G3DSA:3.40.50.12780 1 409 1.2E-130 T 11-10-2018 AFK25_02965 92fb5213e1644bae07e605f045427a91 516 ProSitePatterns PS00455 Putative AMP-binding domain signature. 171 182 - T 11-10-2018 IPR020845 AMP-binding, conserved site AFK25_02965 92fb5213e1644bae07e605f045427a91 516 Pfam PF13193 AMP-binding enzyme C-terminal domain 425 499 1.4E-22 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFK25_02965 92fb5213e1644bae07e605f045427a91 516 Pfam PF00501 AMP-binding enzyme 8 416 5.0E-119 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFK25_02965 92fb5213e1644bae07e605f045427a91 516 Gene3D G3DSA:3.30.300.310 412 515 4.8E-38 T 11-10-2018 AFK25_02965 92fb5213e1644bae07e605f045427a91 516 SUPERFAMILY SSF56801 3 511 1.13E-169 T 11-10-2018 AFK25_02965 92fb5213e1644bae07e605f045427a91 516 PRINTS PR00154 AMP-binding signature 166 177 6.0E-5 T 11-10-2018 IPR020459 AMP-binding AFK25_02965 92fb5213e1644bae07e605f045427a91 516 PRINTS PR00154 AMP-binding signature 178 186 6.0E-5 T 11-10-2018 IPR020459 AMP-binding AFK25_13995 a879fab251ef0897b5dea04ed786a00f 1084 Pfam PF02310 B12 binding domain 12 112 1.0E-12 T 11-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFK25_13995 a879fab251ef0897b5dea04ed786a00f 1084 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 10 123 9.3E-17 T 11-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFK25_13995 a879fab251ef0897b5dea04ed786a00f 1084 SUPERFAMILY SSF52242 4 143 6.28E-42 T 11-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFK25_13995 a879fab251ef0897b5dea04ed786a00f 1084 Gene3D G3DSA:3.20.20.240 486 1084 1.2E-186 T 11-10-2018 AFK25_13995 a879fab251ef0897b5dea04ed786a00f 1084 Pfam PF01642 Methylmalonyl-CoA mutase 559 1078 6.0E-143 T 11-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFK25_13995 a879fab251ef0897b5dea04ed786a00f 1084 Hamap MF_02050 Fused isobutyryl-CoA mutase [icmF]. 10 1084 17.287 T 11-10-2018 IPR033669 Fused isobutyryl-CoA mutase GO:0003924|GO:0005525|GO:0006637|GO:0031419|GO:0034784|GO:0047727 AFK25_13995 a879fab251ef0897b5dea04ed786a00f 1084 Pfam PF03308 ArgK protein 165 408 1.2E-45 T 11-10-2018 AFK25_13995 a879fab251ef0897b5dea04ed786a00f 1084 SUPERFAMILY SSF52540 149 462 1.06E-63 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_13995 a879fab251ef0897b5dea04ed786a00f 1084 Gene3D G3DSA:3.40.50.280 6 149 2.3E-60 T 11-10-2018 AFK25_13995 a879fab251ef0897b5dea04ed786a00f 1084 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 560 1083 3.1E-116 T 11-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFK25_13995 a879fab251ef0897b5dea04ed786a00f 1084 SUPERFAMILY SSF51703 500 1080 8.11E-154 T 11-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFK25_13995 a879fab251ef0897b5dea04ed786a00f 1084 Gene3D G3DSA:3.40.50.300 198 406 2.0E-61 T 11-10-2018 AFK25_10465 a134b65e60ede5c1208822c353909224 118 Pfam PF02410 Ribosomal silencing factor during starvation 10 104 1.1E-27 T 11-10-2018 AFK25_10465 a134b65e60ede5c1208822c353909224 118 Hamap MF_01477 Ribosomal silencing factor RsfS [rsfS]. 2 105 25.633 T 11-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS AFK25_10465 a134b65e60ede5c1208822c353909224 118 TIGRFAM TIGR00090 rsfS_iojap_ybeB: ribosome silencing factor 8 104 3.5E-37 T 11-10-2018 IPR004394 Protein Iojap/ribosomal silencing factor RsfS AFK25_10465 a134b65e60ede5c1208822c353909224 118 Gene3D G3DSA:3.30.460.10 1 108 1.4E-40 T 11-10-2018 AFK25_10465 a134b65e60ede5c1208822c353909224 118 SUPERFAMILY SSF81301 4 113 1.96E-41 T 11-10-2018 AFK25_04295 22f12704f8461819e396c59d2887970a 421 SUPERFAMILY SSF53850 40 418 2.84E-86 T 11-10-2018 AFK25_04295 22f12704f8461819e396c59d2887970a 421 Gene3D G3DSA:3.40.190.10 31 418 5.5E-92 T 11-10-2018 AFK25_04295 22f12704f8461819e396c59d2887970a 421 Pfam PF01547 Bacterial extracellular solute-binding protein 58 335 3.8E-44 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFK25_02915 7ade0ca74d45271e3f65912e09a04095 275 SUPERFAMILY SSF161098 6 274 4.39E-74 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_02915 7ade0ca74d45271e3f65912e09a04095 275 Gene3D G3DSA:1.10.3720.10 2 262 1.1E-63 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_02915 7ade0ca74d45271e3f65912e09a04095 275 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 84 268 2.1E-20 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_06700 fff0ddf8102c066efba24264a82d25e6 237 SUPERFAMILY SSF51735 2 236 1.51E-75 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_06700 fff0ddf8102c066efba24264a82d25e6 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 6.3E-41 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_06700 fff0ddf8102c066efba24264a82d25e6 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 166 183 6.3E-41 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_06700 fff0ddf8102c066efba24264a82d25e6 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 199 219 6.3E-41 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_06700 fff0ddf8102c066efba24264a82d25e6 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 119 135 6.3E-41 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_06700 fff0ddf8102c066efba24264a82d25e6 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 145 164 6.3E-41 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_06700 fff0ddf8102c066efba24264a82d25e6 237 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 72 83 6.3E-41 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_06700 fff0ddf8102c066efba24264a82d25e6 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 145 164 9.1E-7 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_06700 fff0ddf8102c066efba24264a82d25e6 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 72 83 9.1E-7 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_06700 fff0ddf8102c066efba24264a82d25e6 237 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 125 133 9.1E-7 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_06700 fff0ddf8102c066efba24264a82d25e6 237 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 235 2.6E-56 T 11-10-2018 AFK25_06700 fff0ddf8102c066efba24264a82d25e6 237 Gene3D G3DSA:3.40.50.720 1 236 3.0E-74 T 11-10-2018 AFK25_00765 a7850019e89fe5cb5e2b102006fc4a26 246 PIRSF PIRSF001430 1 246 5.3E-86 T 11-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_00765 a7850019e89fe5cb5e2b102006fc4a26 246 Gene3D G3DSA:3.30.70.580 1 106 5.1E-36 T 11-10-2018 AFK25_00765 a7850019e89fe5cb5e2b102006fc4a26 246 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 2 239 5.3E-72 T 11-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_00765 a7850019e89fe5cb5e2b102006fc4a26 246 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 244 36.285 T 11-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_00765 a7850019e89fe5cb5e2b102006fc4a26 246 Gene3D G3DSA:3.30.70.660 107 243 4.0E-50 T 11-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 AFK25_00765 a7850019e89fe5cb5e2b102006fc4a26 246 SUPERFAMILY SSF55120 1 246 2.88E-85 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_00765 a7850019e89fe5cb5e2b102006fc4a26 246 Pfam PF01416 tRNA pseudouridine synthase 143 245 2.6E-31 T 11-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_00765 a7850019e89fe5cb5e2b102006fc4a26 246 Pfam PF01416 tRNA pseudouridine synthase 9 104 6.1E-10 T 11-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_13835 d751bfc6efa9dfba3ee3bda0cecbe766 473 Gene3D G3DSA:2.40.10.170 1 82 1.1E-35 T 11-10-2018 AFK25_13835 d751bfc6efa9dfba3ee3bda0cecbe766 473 SMART SM00382 150 413 3.0E-7 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_13835 d751bfc6efa9dfba3ee3bda0cecbe766 473 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 138 351 6.2E-68 T 11-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFK25_13835 d751bfc6efa9dfba3ee3bda0cecbe766 473 SUPERFAMILY SSF50615 2 82 6.8E-30 T 11-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFK25_13835 d751bfc6efa9dfba3ee3bda0cecbe766 473 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 342 351 - T 11-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFK25_13835 d751bfc6efa9dfba3ee3bda0cecbe766 473 Gene3D G3DSA:3.40.50.300 84 352 3.1E-117 T 11-10-2018 AFK25_13835 d751bfc6efa9dfba3ee3bda0cecbe766 473 SUPERFAMILY SSF52540 84 356 6.54E-90 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_13835 d751bfc6efa9dfba3ee3bda0cecbe766 473 Gene3D G3DSA:1.10.1140.10 354 472 4.8E-58 T 11-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFK25_13835 d751bfc6efa9dfba3ee3bda0cecbe766 473 TIGRFAM TIGR01039 atpD: ATP synthase F1, beta subunit 3 469 3.5E-262 T 11-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 AFK25_13835 d751bfc6efa9dfba3ee3bda0cecbe766 473 SUPERFAMILY SSF47917 354 469 2.38E-53 T 11-10-2018 AFK25_13835 d751bfc6efa9dfba3ee3bda0cecbe766 473 Hamap MF_01347 ATP synthase subunit beta [atpB]. 1 469 58.787 T 11-10-2018 IPR005722 ATP synthase, F1 complex, beta subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-2151201|Reactome: R-HSA-8949613 AFK25_13835 d751bfc6efa9dfba3ee3bda0cecbe766 473 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 6 80 8.4E-26 T 11-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFK25_06160 bbaa77fa767742fdf1f2acc09dbb9638 334 SMART SM00797 24 320 6.8E-140 T 11-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B AFK25_06160 bbaa77fa767742fdf1f2acc09dbb9638 334 Gene3D G3DSA:2.40.100.10 193 330 8.4E-50 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily AFK25_06160 bbaa77fa767742fdf1f2acc09dbb9638 334 TIGRFAM TIGR00724 urea_amlyse_rel: biotin-dependent carboxylase uncharacterized domain 3 328 7.2E-101 T 11-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B AFK25_06160 bbaa77fa767742fdf1f2acc09dbb9638 334 SUPERFAMILY SSF50891 195 310 1.35E-9 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily AFK25_06160 bbaa77fa767742fdf1f2acc09dbb9638 334 Pfam PF02626 Carboxyltransferase domain, subdomain A and B 26 303 3.1E-95 T 11-10-2018 IPR003778 Carboxyltransferase domain, subdomain A and B AFK25_09810 287d4368094ebcd95644b4095910b3ea 149 TIGRFAM TIGR01529 argR_whole: arginine repressor 5 149 8.2E-55 T 11-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 AFK25_09810 287d4368094ebcd95644b4095910b3ea 149 SUPERFAMILY SSF55252 80 149 3.14E-22 T 11-10-2018 IPR036251 Arginine repressor, C-terminal domain superfamily GO:0034618|GO:0051259 AFK25_09810 287d4368094ebcd95644b4095910b3ea 149 Hamap MF_00173 Arginine repressor [argR]. 1 149 72.347 T 11-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 AFK25_09810 287d4368094ebcd95644b4095910b3ea 149 ProDom PD007402 ARGININE REPRESSOR TRANSCRIPTION BIOSYNTHESIS DNA-BINDING REGULATION AMINO-ACID ARGR TRANSCRIPTIONAL FAMILY 87 149 9.0E-25 T 11-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 AFK25_09810 287d4368094ebcd95644b4095910b3ea 149 Gene3D G3DSA:3.30.1360.40 68 149 1.5E-32 T 11-10-2018 AFK25_09810 287d4368094ebcd95644b4095910b3ea 149 Pfam PF01316 Arginine repressor, DNA binding domain 1 70 3.9E-31 T 11-10-2018 IPR020900 Arginine repressor, DNA-binding domain GO:0003700|GO:0006355|GO:0006525 AFK25_09810 287d4368094ebcd95644b4095910b3ea 149 Pfam PF02863 Arginine repressor, C-terminal domain 81 145 9.1E-26 T 11-10-2018 IPR020899 Arginine repressor, C-terminal GO:0034618|GO:0051259 AFK25_09810 287d4368094ebcd95644b4095910b3ea 149 SUPERFAMILY SSF46785 5 78 1.13E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_09810 287d4368094ebcd95644b4095910b3ea 149 PRINTS PR01467 Bacterial arginine repressor signature 21 34 3.1E-29 T 11-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 AFK25_09810 287d4368094ebcd95644b4095910b3ea 149 PRINTS PR01467 Bacterial arginine repressor signature 118 133 3.1E-29 T 11-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 AFK25_09810 287d4368094ebcd95644b4095910b3ea 149 PRINTS PR01467 Bacterial arginine repressor signature 37 52 3.1E-29 T 11-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 AFK25_09810 287d4368094ebcd95644b4095910b3ea 149 PRINTS PR01467 Bacterial arginine repressor signature 88 101 3.1E-29 T 11-10-2018 IPR001669 Arginine repressor GO:0003700|GO:0006355 AFK25_09810 287d4368094ebcd95644b4095910b3ea 149 Gene3D G3DSA:1.10.10.10 4 67 2.2E-30 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 SUPERFAMILY SSF57783 575 612 1.87E-13 T 11-10-2018 AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 Gene3D G3DSA:3.40.50.140 1 134 9.9E-55 T 11-10-2018 AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 SMART SM00437 242 510 1.8E-121 T 11-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 279 302 - T 11-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 SMART SM00436 104 192 5.4E-50 T 11-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 Gene3D G3DSA:2.70.20.10 184 457 1.0E-167 T 11-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 617 655 4.1E-13 T 11-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 577 612 3.2E-15 T 11-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 659 687 0.0027 T 11-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 Gene3D G3DSA:1.10.460.10 135 550 1.0E-167 T 11-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 473 487 2.8E-37 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 370 386 2.8E-37 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 293 302 2.8E-37 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 77 90 2.8E-37 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 162 180 2.8E-37 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 Gene3D G3DSA:1.10.290.10 250 385 1.0E-167 T 11-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 Pfam PF01131 DNA topoisomerase 128 547 2.2E-134 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 Pfam PF01751 Toprim domain 5 113 2.7E-30 T 11-10-2018 IPR006171 TOPRIM domain AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 Gene3D G3DSA:3.30.65.10 559 616 1.8E-14 T 11-10-2018 AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 SMART SM00493 3 103 4.5E-32 T 11-10-2018 IPR006171 TOPRIM domain AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 SUPERFAMILY SSF56712 4 589 1.83E-200 T 11-10-2018 IPR023405 DNA topoisomerase, type IA, core domain AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 Hamap MF_00952 DNA topoisomerase 1 [topA]. 3 642 55.346 T 11-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 AFK25_05620 ed231f8a5c3806c18163126182bb9b6b 689 TIGRFAM TIGR01051 topA_bact: DNA topoisomerase I 5 611 1.4E-262 T 11-10-2018 IPR005733 DNA topoisomerase I, bacterial-type GO:0003677|GO:0003917|GO:0006265 AFK25_00255 cbda06ce70092c6ded7aebcbafa4e00f 274 Gene3D G3DSA:1.10.10.10 1 73 6.3E-31 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_00255 cbda06ce70092c6ded7aebcbafa4e00f 274 SUPERFAMILY SSF46785 2 73 3.63E-26 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_00255 cbda06ce70092c6ded7aebcbafa4e00f 274 SUPERFAMILY SSF53271 93 256 2.41E-40 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like AFK25_00255 cbda06ce70092c6ded7aebcbafa4e00f 274 TIGRFAM TIGR01743 purR_Bsub: pur operon repressor PurR 3 270 5.0E-125 T 11-10-2018 IPR010078 Pur operon repressor GO:0003677|GO:0045892|GO:0045982 AFK25_00255 cbda06ce70092c6ded7aebcbafa4e00f 274 Gene3D G3DSA:3.40.50.2020 74 274 1.0E-62 T 11-10-2018 AFK25_00255 cbda06ce70092c6ded7aebcbafa4e00f 274 Pfam PF00156 Phosphoribosyl transferase domain 114 263 3.4E-23 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFK25_00255 cbda06ce70092c6ded7aebcbafa4e00f 274 Pfam PF09182 Bacterial purine repressor, N-terminal 4 73 1.3E-30 T 11-10-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 AFK25_00255 cbda06ce70092c6ded7aebcbafa4e00f 274 ProDom PD029816 REPRESSOR OPERON PUR TRANSCRIPTION PURINE TRANSCRIPTIONAL PURR REGULATION DNA-BINDING GLYCOSYLTRANSFERASE 9 74 9.0E-29 T 11-10-2018 IPR015265 Bacterial purine repressor, N-terminal GO:0003677|GO:0006355 AFK25_08045 d728bc46dc6d126fef59f2d3972f1821 246 Pfam PF00005 ABC transporter 19 164 4.2E-26 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_08045 d728bc46dc6d126fef59f2d3972f1821 246 Gene3D G3DSA:3.40.50.300 4 243 9.1E-64 T 11-10-2018 AFK25_08045 d728bc46dc6d126fef59f2d3972f1821 246 SMART SM00382 28 213 2.8E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_08045 d728bc46dc6d126fef59f2d3972f1821 246 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_08045 d728bc46dc6d126fef59f2d3972f1821 246 SUPERFAMILY SSF52540 4 228 1.84E-58 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_09410 e088b1ef25007d95e4d11f7800bee873 146 TIGRFAM TIGR01925 spIIAB: anti-sigma F factor 1 137 1.7E-70 T 11-10-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0042174|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 AFK25_09410 e088b1ef25007d95e4d11f7800bee873 146 Pfam PF13581 Histidine kinase-like ATPase domain 10 136 7.8E-24 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_09410 e088b1ef25007d95e4d11f7800bee873 146 Hamap MF_00637 Anti-sigma F factor [spoIIAB]. 1 140 36.759 T 11-10-2018 IPR010194 Anti-sigma F factor GO:0004674|GO:0005524|GO:0006468|GO:0016989|GO:0042174|GO:0045892 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 AFK25_09410 e088b1ef25007d95e4d11f7800bee873 146 SMART SM00387 35 140 3.6E-11 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_09410 e088b1ef25007d95e4d11f7800bee873 146 SUPERFAMILY SSF55874 28 134 2.1E-24 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_09410 e088b1ef25007d95e4d11f7800bee873 146 Gene3D G3DSA:3.30.565.10 1 142 1.5E-34 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_05760 9b77d55ed90d9d3d3b37b6aba468e950 678 Pfam PF00771 FHIPEP family 15 667 2.6E-278 T 11-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFK25_05760 9b77d55ed90d9d3d3b37b6aba468e950 678 Gene3D G3DSA:1.10.490.80 577 675 6.8E-29 T 11-10-2018 AFK25_05760 9b77d55ed90d9d3d3b37b6aba468e950 678 TIGRFAM TIGR01398 FlhA: flagellar biosynthesis protein FlhA 4 675 8.5E-279 T 11-10-2018 IPR006301 Flagellar biosynthesis protein FlhA GO:0016021|GO:0044780 AFK25_05760 9b77d55ed90d9d3d3b37b6aba468e950 678 ProSitePatterns PS00994 Bacterial export FHIPEP family signature. 126 149 - T 11-10-2018 IPR025505 FHIPEP conserved site AFK25_05760 9b77d55ed90d9d3d3b37b6aba468e950 678 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 22 35 4.2E-55 T 11-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFK25_05760 9b77d55ed90d9d3d3b37b6aba468e950 678 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 59 78 4.2E-55 T 11-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFK25_05760 9b77d55ed90d9d3d3b37b6aba468e950 678 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 140 158 4.2E-55 T 11-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFK25_05760 9b77d55ed90d9d3d3b37b6aba468e950 678 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 121 137 4.2E-55 T 11-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFK25_05760 9b77d55ed90d9d3d3b37b6aba468e950 678 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 221 235 4.2E-55 T 11-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFK25_05760 9b77d55ed90d9d3d3b37b6aba468e950 678 PRINTS PR00949 Type III secretion system inner membrane A protein family signature 170 187 4.2E-55 T 11-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFK25_05760 9b77d55ed90d9d3d3b37b6aba468e950 678 Gene3D G3DSA:1.10.8.540 486 575 8.4E-33 T 11-10-2018 AFK25_05760 9b77d55ed90d9d3d3b37b6aba468e950 678 Gene3D G3DSA:3.40.30.60 342 485 9.1E-56 T 11-10-2018 AFK25_05760 9b77d55ed90d9d3d3b37b6aba468e950 678 PIRSF PIRSF005419 1 678 8.9E-266 T 11-10-2018 IPR001712 Type III secretion system FHIPEP GO:0009306|GO:0016020 AFK25_08360 9c650306dc4f749aae1954e23bdd2832 476 SUPERFAMILY SSF53720 3 473 5.76E-157 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFK25_08360 9c650306dc4f749aae1954e23bdd2832 476 Gene3D G3DSA:3.40.309.10 252 440 3.1E-161 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFK25_08360 9c650306dc4f749aae1954e23bdd2832 476 Gene3D G3DSA:3.40.605.10 27 461 3.1E-161 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFK25_08360 9c650306dc4f749aae1954e23bdd2832 476 Pfam PF00171 Aldehyde dehydrogenase family 13 469 1.2E-164 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFK25_12900 bd79eff60b0c08f03e2824280681aba6 511 Pfam PF01676 Metalloenzyme superfamily 4 498 1.6E-79 T 11-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 AFK25_12900 bd79eff60b0c08f03e2824280681aba6 511 TIGRFAM TIGR01307 pgm_bpd_ind: phosphoglycerate mutase (2,3-diphosphoglycerate-independent) 4 509 1.0E-211 T 11-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFK25_12900 bd79eff60b0c08f03e2824280681aba6 511 Gene3D G3DSA:3.40.720.10 5 509 2.0E-239 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFK25_12900 bd79eff60b0c08f03e2824280681aba6 511 SUPERFAMILY SSF64158 77 310 1.83E-93 T 11-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFK25_12900 bd79eff60b0c08f03e2824280681aba6 511 Hamap MF_01038 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [gpmI]. 4 510 50.48 T 11-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFK25_12900 bd79eff60b0c08f03e2824280681aba6 511 Gene3D G3DSA:3.40.1450.10 77 312 2.0E-239 T 11-10-2018 IPR036646 BPG-independent phosphoglycerate mutase, domain B superfamily GO:0004619|GO:0005737 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFK25_12900 bd79eff60b0c08f03e2824280681aba6 511 PIRSF PIRSF001492 1 511 9.2E-208 T 11-10-2018 IPR005995 Phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent GO:0004619|GO:0006007 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFK25_12900 bd79eff60b0c08f03e2824280681aba6 511 Pfam PF06415 BPG-independent PGAM N-terminus (iPGM_N) 82 299 3.8E-85 T 11-10-2018 IPR011258 BPG-independent PGAM, N-terminal GO:0004619|GO:0005737|GO:0006007|GO:0030145 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFK25_12900 bd79eff60b0c08f03e2824280681aba6 511 SUPERFAMILY SSF53649 3 509 3.14E-77 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AFK25_09660 b0c9049f30a3df9797e43e0ab1aee0c3 315 Pfam PF00753 Metallo-beta-lactamase superfamily 16 227 2.5E-25 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_09660 b0c9049f30a3df9797e43e0ab1aee0c3 315 SUPERFAMILY SSF56281 8 312 7.86E-51 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_09660 b0c9049f30a3df9797e43e0ab1aee0c3 315 SMART SM00849 17 227 7.5E-25 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_09660 b0c9049f30a3df9797e43e0ab1aee0c3 315 Gene3D G3DSA:3.60.15.10 1 254 1.4E-53 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_10290 085221b25a3070aa46974b84263a09b4 268 Pfam PF03618 Kinase/pyrophosphorylase 5 260 6.6E-97 T 11-10-2018 IPR005177 Bifunctional kinase-pyrophosphorylase GO:0005524|GO:0016772 AFK25_10290 085221b25a3070aa46974b84263a09b4 268 Hamap MF_00921 Putative pyruvate, phosphate dikinase regulatory protein. 3 265 60.489 T 11-10-2018 IPR026565 Putative pyruvate, phosphate dikinase regulatory protein AFK25_10070 ca8c3c945de5704fa0a94aa1521361eb 289 Gene3D G3DSA:3.40.630.10 1 288 4.8E-48 T 11-10-2018 AFK25_10070 ca8c3c945de5704fa0a94aa1521361eb 289 Pfam PF00246 Zinc carboxypeptidase 12 228 5.5E-30 T 11-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AFK25_10070 ca8c3c945de5704fa0a94aa1521361eb 289 SUPERFAMILY SSF53187 2 285 8.93E-51 T 11-10-2018 AFK25_10070 ca8c3c945de5704fa0a94aa1521361eb 289 SMART SM00631 1 277 1.1E-20 T 11-10-2018 IPR000834 Peptidase M14, carboxypeptidase A GO:0004181|GO:0006508|GO:0008270 AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 Gene3D G3DSA:3.30.70.1320 132 330 2.0E-261 T 11-10-2018 AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 Gene3D G3DSA:3.30.2090.10 703 789 2.0E-261 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 Gene3D G3DSA:3.30.2090.10 174 277 2.0E-261 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 Gene3D G3DSA:1.20.1640.10 11 506 2.0E-261 T 11-10-2018 AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 PRINTS PR00702 Acriflavin resistance protein family signature 361 382 7.9E-48 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 PRINTS PR00702 Acriflavin resistance protein family signature 444 467 7.9E-48 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 PRINTS PR00702 Acriflavin resistance protein family signature 469 492 7.9E-48 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 PRINTS PR00702 Acriflavin resistance protein family signature 539 556 7.9E-48 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 PRINTS PR00702 Acriflavin resistance protein family signature 11 35 7.9E-48 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 PRINTS PR00702 Acriflavin resistance protein family signature 39 57 7.9E-48 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 PRINTS PR00702 Acriflavin resistance protein family signature 389 413 7.9E-48 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 PRINTS PR00702 Acriflavin resistance protein family signature 334 357 7.9E-48 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 Pfam PF00873 AcrB/AcrD/AcrF family 5 1008 1.4E-209 T 11-10-2018 IPR001036 Acriflavin resistance protein GO:0016020|GO:0022857|GO:0055085 AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 Gene3D G3DSA:3.30.70.1430 554 651 2.0E-261 T 11-10-2018 AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 Gene3D G3DSA:1.20.1640.10 507 1005 2.0E-261 T 11-10-2018 AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 SUPERFAMILY SSF82714 704 786 6.67E-11 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 SUPERFAMILY SSF82693 147 318 8.37E-7 T 11-10-2018 AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 Gene3D G3DSA:3.30.70.1430 41 797 2.0E-261 T 11-10-2018 AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 SUPERFAMILY SSF82693 41 124 1.1E-17 T 11-10-2018 AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 SUPERFAMILY SSF82693 552 644 4.71E-8 T 11-10-2018 AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 SUPERFAMILY SSF82866 787 1012 2.22E-44 T 11-10-2018 AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 Gene3D G3DSA:3.30.70.1440 652 847 2.0E-261 T 11-10-2018 AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 SUPERFAMILY SSF82714 179 273 4.32E-9 T 11-10-2018 IPR027463 Multidrug efflux transporter AcrB TolC docking domain, DN/DC subdomains AFK25_10735 a1e363635be7b8a06dec5e9074e9a52a 1019 SUPERFAMILY SSF82866 298 493 1.57E-39 T 11-10-2018 AFK25_06850 8d745f33f072198d98f26882ec4413c6 422 Gene3D G3DSA:3.90.1150.60 17 411 5.8E-183 T 11-10-2018 AFK25_06850 8d745f33f072198d98f26882ec4413c6 422 Gene3D G3DSA:3.40.640.10 58 271 5.8E-183 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_06850 8d745f33f072198d98f26882ec4413c6 422 SUPERFAMILY SSF53383 57 398 2.42E-49 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_06850 8d745f33f072198d98f26882ec4413c6 422 Pfam PF06838 Methionine gamma-lyase 13 414 1.9E-212 T 11-10-2018 IPR009651 Putative methionine gamma-lyase AFK25_14030 789477598e575195e63c52a9ab2c0458 392 Gene3D G3DSA:3.30.870.10 32 217 3.3E-43 T 11-10-2018 AFK25_14030 789477598e575195e63c52a9ab2c0458 392 Gene3D G3DSA:3.30.870.10 218 365 9.1E-27 T 11-10-2018 AFK25_14030 789477598e575195e63c52a9ab2c0458 392 Pfam PF13091 PLD-like domain 56 193 1.1E-11 T 11-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFK25_14030 789477598e575195e63c52a9ab2c0458 392 Pfam PF13091 PLD-like domain 233 359 2.8E-28 T 11-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFK25_14030 789477598e575195e63c52a9ab2c0458 392 SUPERFAMILY SSF56024 35 209 8.3E-45 T 11-10-2018 AFK25_14030 789477598e575195e63c52a9ab2c0458 392 SUPERFAMILY SSF56024 223 379 4.93E-42 T 11-10-2018 AFK25_14030 789477598e575195e63c52a9ab2c0458 392 SMART SM00155 305 332 1.9E-6 T 11-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AFK25_14030 789477598e575195e63c52a9ab2c0458 392 SMART SM00155 133 160 0.0013 T 11-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AFK25_14030 789477598e575195e63c52a9ab2c0458 392 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 31 392 1.8E-105 T 11-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 AFK25_09115 8e7a37198755691592202d9495629219 173 SMART SM00257 122 168 1.2E-11 T 11-10-2018 IPR018392 LysM domain AFK25_09115 8e7a37198755691592202d9495629219 173 SUPERFAMILY SSF54106 121 168 4.71E-9 T 11-10-2018 AFK25_09115 8e7a37198755691592202d9495629219 173 Pfam PF01476 LysM domain 123 168 2.9E-10 T 11-10-2018 IPR018392 LysM domain AFK25_09115 8e7a37198755691592202d9495629219 173 Gene3D G3DSA:3.10.350.10 107 172 2.1E-14 T 11-10-2018 IPR036779 LysM domain superfamily AFK25_04230 0de545266ac3cd52ad4e33d70cb57bd4 389 SUPERFAMILY SSF103473 4 381 3.27E-76 T 11-10-2018 IPR036259 MFS transporter superfamily AFK25_04230 0de545266ac3cd52ad4e33d70cb57bd4 389 Pfam PF07690 Major Facilitator Superfamily 11 322 1.3E-55 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFK25_04230 0de545266ac3cd52ad4e33d70cb57bd4 389 Gene3D G3DSA:1.20.1250.20 2 380 1.3E-82 T 11-10-2018 AFK25_04230 0de545266ac3cd52ad4e33d70cb57bd4 389 PRINTS PR01035 Tetracycline resistance protein signature 17 33 1.6E-31 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFK25_04230 0de545266ac3cd52ad4e33d70cb57bd4 389 PRINTS PR01035 Tetracycline resistance protein signature 331 354 1.6E-31 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFK25_04230 0de545266ac3cd52ad4e33d70cb57bd4 389 PRINTS PR01035 Tetracycline resistance protein signature 271 292 1.6E-31 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFK25_04230 0de545266ac3cd52ad4e33d70cb57bd4 389 PRINTS PR01035 Tetracycline resistance protein signature 74 98 1.6E-31 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFK25_04230 0de545266ac3cd52ad4e33d70cb57bd4 389 PRINTS PR01035 Tetracycline resistance protein signature 160 180 1.6E-31 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFK25_04230 0de545266ac3cd52ad4e33d70cb57bd4 389 PRINTS PR01035 Tetracycline resistance protein signature 243 263 1.6E-31 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFK25_04230 0de545266ac3cd52ad4e33d70cb57bd4 389 PRINTS PR01035 Tetracycline resistance protein signature 132 154 1.6E-31 T 11-10-2018 IPR001958 Tetracycline resistance protein TetA/multidrug resistance protein MdtG GO:0005215 AFK25_00300 8924a489fbe58a57526e344d8d65eee2 178 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 1.2E-15 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFK25_00300 8924a489fbe58a57526e344d8d65eee2 178 Gene3D G3DSA:2.10.260.10 1 49 3.8E-24 T 11-10-2018 AFK25_00300 8924a489fbe58a57526e344d8d65eee2 178 Pfam PF15714 Stage V sporulation protein T C-terminal, transcription factor 54 177 4.3E-47 T 11-10-2018 IPR039472 Sporulation stage V protein T, GAF domain AFK25_00300 8924a489fbe58a57526e344d8d65eee2 178 TIGRFAM TIGR02851 spore_V_T: stage V sporulation protein T 2 177 5.6E-91 T 11-10-2018 IPR014213 Sporulation stage V, protein T AFK25_00300 8924a489fbe58a57526e344d8d65eee2 178 SMART SM00966 8 52 1.1E-10 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFK25_00300 8924a489fbe58a57526e344d8d65eee2 178 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 9 51 1.1E-10 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFK25_00300 8924a489fbe58a57526e344d8d65eee2 178 SUPERFAMILY SSF89447 1 52 9.03E-15 T 11-10-2018 IPR037914 SpoVT-AbrB domain superfamily AFK25_00300 8924a489fbe58a57526e344d8d65eee2 178 SUPERFAMILY SSF55781 82 177 3.68E-6 T 11-10-2018 AFK25_00300 8924a489fbe58a57526e344d8d65eee2 178 Gene3D G3DSA:3.30.450.40 56 178 7.1E-47 T 11-10-2018 IPR029016 GAF-like domain superfamily AFK25_00300 8924a489fbe58a57526e344d8d65eee2 178 PIRSF PIRSF026579 1 178 1.5E-96 T 11-10-2018 IPR014213 Sporulation stage V, protein T AFK25_04525 399c050d370226317988135320aef077 240 Pfam PF04055 Radical SAM superfamily 28 123 3.7E-12 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFK25_04525 399c050d370226317988135320aef077 240 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 4 237 34.288 T 11-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 AFK25_04525 399c050d370226317988135320aef077 240 Gene3D G3DSA:3.20.20.70 4 234 9.0E-31 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_04525 399c050d370226317988135320aef077 240 Pfam PF13394 4Fe-4S single cluster domain 26 111 2.4E-11 T 11-10-2018 AFK25_04525 399c050d370226317988135320aef077 240 PIRSF PIRSF000370 2 240 1.8E-53 T 11-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 AFK25_04525 399c050d370226317988135320aef077 240 TIGRFAM TIGR03365 Bsubt_queE: 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE 3 240 9.4E-118 T 11-10-2018 IPR017742 7-carboxy-7-deazaguanine synthase KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 AFK25_04525 399c050d370226317988135320aef077 240 SUPERFAMILY SSF102114 26 130 4.45E-14 T 11-10-2018 AFK25_05750 8e6c0594745ca313535b61aea5379477 256 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 197 216 6.6E-28 T 11-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 AFK25_05750 8e6c0594745ca313535b61aea5379477 256 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 16 37 6.6E-28 T 11-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 AFK25_05750 8e6c0594745ca313535b61aea5379477 256 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 175 197 6.6E-28 T 11-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 AFK25_05750 8e6c0594745ca313535b61aea5379477 256 PRINTS PR00953 Type III secretion system inner membrane R protein family signature 73 92 6.6E-28 T 11-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 AFK25_05750 8e6c0594745ca313535b61aea5379477 256 TIGRFAM TIGR01400 fliR: flagellar biosynthetic protein FliR 8 250 2.5E-69 T 11-10-2018 IPR006303 Flagellar biosynthesis protein FliR GO:0016021|GO:0044780 AFK25_05750 8e6c0594745ca313535b61aea5379477 256 Pfam PF01311 Bacterial export proteins, family 1 8 240 1.1E-71 T 11-10-2018 IPR002010 Type III secretion system inner membrane R protein GO:0006605|GO:0016020 AFK25_08310 166ee066afd5e1f26a87067a5f8b43d0 396 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 2.2E-29 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFK25_08310 166ee066afd5e1f26a87067a5f8b43d0 396 SUPERFAMILY SSF47203 227 385 3.06E-52 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFK25_08310 166ee066afd5e1f26a87067a5f8b43d0 396 Gene3D G3DSA:2.40.110.10 121 234 4.6E-47 T 11-10-2018 AFK25_08310 166ee066afd5e1f26a87067a5f8b43d0 396 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFK25_08310 166ee066afd5e1f26a87067a5f8b43d0 396 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 375 1.7E-45 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFK25_08310 166ee066afd5e1f26a87067a5f8b43d0 396 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 9.5E-39 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFK25_08310 166ee066afd5e1f26a87067a5f8b43d0 396 PIRSF PIRSF016578 125 379 3.5E-8 T 11-10-2018 AFK25_08310 166ee066afd5e1f26a87067a5f8b43d0 396 PIRSF PIRSF016578 6 97 0.002 T 11-10-2018 AFK25_08310 166ee066afd5e1f26a87067a5f8b43d0 396 Gene3D G3DSA:1.20.140.10 235 386 1.7E-46 T 11-10-2018 AFK25_08310 166ee066afd5e1f26a87067a5f8b43d0 396 Gene3D G3DSA:1.10.540.10 1 120 1.1E-41 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFK25_08310 166ee066afd5e1f26a87067a5f8b43d0 396 SUPERFAMILY SSF56645 1 242 2.23E-94 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFK25_13990 939747104fba4ec5b0e29f3dbc1ca70c 199 Hamap MF_00357 Probable DNA-directed RNA polymerase subunit delta [rpoE]. 26 196 13.83 T 11-10-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 AFK25_13990 939747104fba4ec5b0e29f3dbc1ca70c 199 Gene3D G3DSA:1.10.10.1250 19 99 1.1E-30 T 11-10-2018 IPR038087 DNA-directed RNA polymerase subunit delta domain superfamily AFK25_13990 939747104fba4ec5b0e29f3dbc1ca70c 199 Pfam PF05066 HB1, ASXL, restriction endonuclease HTH domain 31 98 2.8E-8 T 11-10-2018 IPR007759 HB1/Asxl, restriction endonuclease HTH domain GO:0006351|GO:0006355 AFK25_13990 939747104fba4ec5b0e29f3dbc1ca70c 199 TIGRFAM TIGR04567 RNAP_delt_lowGC: DNA-directed RNA polymerase delta subunit 30 108 1.0E-30 T 11-10-2018 IPR029757 DNA-directed RNA polymerase subunit delta GO:0006351|GO:0006355 AFK25_11720 45347ab5260c904fe047e00a7439503a 402 Pfam PF00764 Arginosuccinate synthase 7 391 2.6E-182 T 11-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFK25_11720 45347ab5260c904fe047e00a7439503a 402 Gene3D G3DSA:3.40.50.620 1 173 2.6E-67 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_11720 45347ab5260c904fe047e00a7439503a 402 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 116 127 - T 11-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFK25_11720 45347ab5260c904fe047e00a7439503a 402 TIGRFAM TIGR00032 argG: argininosuccinate synthase 5 393 1.7E-175 T 11-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFK25_11720 45347ab5260c904fe047e00a7439503a 402 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 9 17 - T 11-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFK25_11720 45347ab5260c904fe047e00a7439503a 402 Gene3D G3DSA:3.90.1260.10 174 401 3.6E-92 T 11-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFK25_11720 45347ab5260c904fe047e00a7439503a 402 SUPERFAMILY SSF52402 4 164 2.43E-48 T 11-10-2018 AFK25_11720 45347ab5260c904fe047e00a7439503a 402 SUPERFAMILY SSF69864 170 396 8.24E-94 T 11-10-2018 AFK25_11720 45347ab5260c904fe047e00a7439503a 402 Hamap MF_00005 Argininosuccinate synthase [argG]. 3 396 55.273 T 11-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFK25_03180 e3496c2f3dc9788366d9d031b945eaab 587 SMART SM00642 139 497 9.3E-134 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFK25_03180 e3496c2f3dc9788366d9d031b945eaab 587 Gene3D G3DSA:3.90.400.10 246 299 1.5E-166 T 11-10-2018 AFK25_03180 e3496c2f3dc9788366d9d031b945eaab 587 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 1 121 6.9E-50 T 11-10-2018 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 AFK25_03180 e3496c2f3dc9788366d9d031b945eaab 587 Pfam PF00128 Alpha amylase, catalytic domain 173 469 1.4E-88 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFK25_03180 e3496c2f3dc9788366d9d031b945eaab 587 PIRSF PIRSF001024 110 576 1.1E-52 T 11-10-2018 IPR013777 Alpha-amylase-like GO:0004556|GO:0005509|GO:0005975 AFK25_03180 e3496c2f3dc9788366d9d031b945eaab 587 Gene3D G3DSA:3.20.20.80 133 499 1.5E-166 T 11-10-2018 AFK25_03180 e3496c2f3dc9788366d9d031b945eaab 587 SUPERFAMILY SSF51445 69 506 1.57E-132 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily AFK25_03180 e3496c2f3dc9788366d9d031b945eaab 587 Pfam PF16657 Maltogenic Amylase, C-terminal domain 506 577 8.9E-12 T 11-10-2018 IPR032091 Maltogenic Amylase, C-terminal AFK25_03180 e3496c2f3dc9788366d9d031b945eaab 587 Gene3D G3DSA:2.60.40.1180 506 583 1.4E-18 T 11-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFK25_03180 e3496c2f3dc9788366d9d031b945eaab 587 SUPERFAMILY SSF51011 506 581 5.76E-16 T 11-10-2018 AFK25_03180 e3496c2f3dc9788366d9d031b945eaab 587 Gene3D G3DSA:2.60.40.10 1 125 5.3E-46 T 11-10-2018 IPR013783 Immunoglobulin-like fold AFK25_05225 a0811ca8c7e1b96bf76e5f20319b4319 363 Gene3D G3DSA:3.40.50.2000 4 352 1.9E-110 T 11-10-2018 AFK25_05225 a0811ca8c7e1b96bf76e5f20319b4319 363 Pfam PF03033 Glycosyltransferase family 28 N-terminal domain 3 143 1.2E-48 T 11-10-2018 IPR004276 Glycosyltransferase family 28, N-terminal domain GO:0005975|GO:0016758|GO:0030259 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_05225 a0811ca8c7e1b96bf76e5f20319b4319 363 Hamap MF_00033 UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [murG]. 3 362 34.148 T 11-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_05225 a0811ca8c7e1b96bf76e5f20319b4319 363 SUPERFAMILY SSF53756 1 362 2.47E-110 T 11-10-2018 AFK25_05225 a0811ca8c7e1b96bf76e5f20319b4319 363 Gene3D G3DSA:3.40.50.2000 164 346 1.9E-110 T 11-10-2018 AFK25_05225 a0811ca8c7e1b96bf76e5f20319b4319 363 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 188 354 6.5E-40 T 11-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 AFK25_05225 a0811ca8c7e1b96bf76e5f20319b4319 363 TIGRFAM TIGR01133 murG: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase 1 357 3.3E-104 T 11-10-2018 IPR006009 N-acetylglucosaminyltransferase, MurG GO:0050511 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_09190 4066fd3b0eff06b234972db047c2e71a 349 Gene3D G3DSA:3.40.640.10 37 256 2.8E-97 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_09190 4066fd3b0eff06b234972db047c2e71a 349 Pfam PF00155 Aminotransferase class I and II 72 341 9.0E-39 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFK25_09190 4066fd3b0eff06b234972db047c2e71a 349 Gene3D G3DSA:3.90.1150.10 26 344 2.8E-97 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_09190 4066fd3b0eff06b234972db047c2e71a 349 TIGRFAM TIGR01140 L_thr_O3P_dcar: threonine-phosphate decarboxylase 6 344 1.3E-96 T 11-10-2018 IPR005860 L-threonine-O-3-phosphate decarboxylase GO:0003824|GO:0009236 KEGG: 00860+4.1.1.81|MetaCyc: PWY-5443 AFK25_09190 4066fd3b0eff06b234972db047c2e71a 349 SUPERFAMILY SSF53383 11 346 1.29E-70 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_02985 c20c5391f2efb597531633d48b494d83 789 SUPERFAMILY SSF55073 372 520 7.06E-30 T 11-10-2018 IPR029787 Nucleotide cyclase AFK25_02985 c20c5391f2efb597531633d48b494d83 789 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 144 264 8.7E-20 T 11-10-2018 IPR000014 PAS domain AFK25_02985 c20c5391f2efb597531633d48b494d83 789 Pfam PF13426 PAS domain 156 255 5.0E-14 T 11-10-2018 IPR000014 PAS domain AFK25_02985 c20c5391f2efb597531633d48b494d83 789 SMART SM00091 269 335 0.22 T 11-10-2018 IPR000014 PAS domain AFK25_02985 c20c5391f2efb597531633d48b494d83 789 SMART SM00091 144 209 6.3E-7 T 11-10-2018 IPR000014 PAS domain AFK25_02985 c20c5391f2efb597531633d48b494d83 789 Pfam PF08448 PAS fold 37 131 5.5E-5 T 11-10-2018 IPR013656 PAS fold-4 AFK25_02985 c20c5391f2efb597531633d48b494d83 789 SUPERFAMILY SSF141868 533 780 1.31E-85 T 11-10-2018 IPR035919 EAL domain superfamily AFK25_02985 c20c5391f2efb597531633d48b494d83 789 SUPERFAMILY SSF55785 254 351 2.97E-10 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_02985 c20c5391f2efb597531633d48b494d83 789 SMART SM00267 364 518 6.1E-13 T 11-10-2018 IPR000160 GGDEF domain AFK25_02985 c20c5391f2efb597531633d48b494d83 789 Pfam PF00563 EAL domain 534 768 3.5E-75 T 11-10-2018 IPR001633 EAL domain AFK25_02985 c20c5391f2efb597531633d48b494d83 789 Gene3D G3DSA:3.20.20.450 531 780 7.5E-97 T 11-10-2018 IPR035919 EAL domain superfamily AFK25_02985 c20c5391f2efb597531633d48b494d83 789 Gene3D G3DSA:3.30.450.20 144 255 5.8E-20 T 11-10-2018 AFK25_02985 c20c5391f2efb597531633d48b494d83 789 SUPERFAMILY SSF55785 129 248 1.4E-21 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_02985 c20c5391f2efb597531633d48b494d83 789 Pfam PF00990 Diguanylate cyclase, GGDEF domain 386 513 1.7E-24 T 11-10-2018 IPR000160 GGDEF domain AFK25_02985 c20c5391f2efb597531633d48b494d83 789 SMART SM00052 528 773 9.2E-107 T 11-10-2018 IPR001633 EAL domain AFK25_02985 c20c5391f2efb597531633d48b494d83 789 Gene3D G3DSA:3.30.450.20 256 329 3.0E-7 T 11-10-2018 AFK25_02985 c20c5391f2efb597531633d48b494d83 789 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 387 516 1.8E-20 T 11-10-2018 IPR000160 GGDEF domain AFK25_02985 c20c5391f2efb597531633d48b494d83 789 Pfam PF13188 PAS domain 270 323 2.3E-4 T 11-10-2018 IPR000014 PAS domain AFK25_02985 c20c5391f2efb597531633d48b494d83 789 Gene3D G3DSA:3.30.450.20 8 143 3.4E-13 T 11-10-2018 AFK25_02985 c20c5391f2efb597531633d48b494d83 789 Gene3D G3DSA:3.30.70.270 370 530 2.3E-32 T 11-10-2018 AFK25_02985 c20c5391f2efb597531633d48b494d83 789 SUPERFAMILY SSF55785 38 141 6.77E-8 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_02580 4bb8b1a9698c0978b4166ef8514bf745 377 SUPERFAMILY SSF56281 118 320 4.74E-43 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_02580 4bb8b1a9698c0978b4166ef8514bf745 377 SMART SM00450 7 109 8.3E-15 T 11-10-2018 IPR001763 Rhodanese-like domain AFK25_02580 4bb8b1a9698c0978b4166ef8514bf745 377 Pfam PF00581 Rhodanese-like domain 8 105 6.1E-10 T 11-10-2018 IPR001763 Rhodanese-like domain AFK25_02580 4bb8b1a9698c0978b4166ef8514bf745 377 SMART SM00849 129 291 3.0E-29 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_02580 4bb8b1a9698c0978b4166ef8514bf745 377 SUPERFAMILY SSF52821 3 111 1.57E-20 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_02580 4bb8b1a9698c0978b4166ef8514bf745 377 Gene3D G3DSA:3.40.250.10 2 111 6.8E-20 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_02580 4bb8b1a9698c0978b4166ef8514bf745 377 Gene3D G3DSA:3.60.15.10 115 358 1.6E-56 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_02580 4bb8b1a9698c0978b4166ef8514bf745 377 Pfam PF00753 Metallo-beta-lactamase superfamily 129 287 2.4E-16 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 SUPERFAMILY SSF55424 325 447 7.56E-35 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.3E-14 T 11-10-2018 AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 1.3E-14 T 11-10-2018 AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 238 252 1.3E-14 T 11-10-2018 AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 279 286 1.3E-14 T 11-10-2018 AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 332 434 5.3E-15 T 11-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 309 4.7E-63 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 SUPERFAMILY SSF75169 660 806 4.19E-22 T 11-10-2018 IPR027396 DsrEFH-like AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 Pfam PF00581 Rhodanese-like domain 460 544 8.8E-13 T 11-10-2018 IPR001763 Rhodanese-like domain AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 Gene3D G3DSA:3.50.50.60 116 442 1.4E-192 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 SMART SM00450 456 549 1.5E-23 T 11-10-2018 IPR001763 Rhodanese-like domain AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 Gene3D G3DSA:3.40.250.10 452 550 3.1E-28 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 SUPERFAMILY SSF52821 436 547 2.75E-31 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 Gene3D G3DSA:3.30.110.40 568 644 2.7E-28 T 11-10-2018 IPR036868 TusA-like domain superfamily AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 Pfam PF01206 Sulfurtransferase TusA 575 643 6.4E-21 T 11-10-2018 IPR001455 TusA-like domain AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 Gene3D G3DSA:3.40.1260.10 654 812 9.9E-70 T 11-10-2018 IPR027396 DsrEFH-like AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 SUPERFAMILY SSF64307 559 643 7.85E-24 T 11-10-2018 IPR036868 TusA-like domain superfamily AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 237 253 1.6E-22 T 11-10-2018 AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 107 125 1.6E-22 T 11-10-2018 AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 264 286 1.6E-22 T 11-10-2018 AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.6E-22 T 11-10-2018 AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 1.6E-22 T 11-10-2018 AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 Pfam PF13686 DsrE/DsrF/DrsH-like family 660 811 2.8E-62 T 11-10-2018 IPR032836 DsrE2-like family AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 Gene3D G3DSA:3.50.50.60 4 342 1.4E-192 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 576 600 - T 11-10-2018 IPR001455 TusA-like domain AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 SUPERFAMILY SSF51905 1 319 1.99E-45 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_01680 249aa2ea138dfb153f140b4c4686a9ad 812 TIGRFAM TIGR03385 CoA_CoA_reduc: CoA-disulfide reductase 4 442 1.8E-176 T 11-10-2018 IPR017758 Coenzyme A disulphide reductase GO:0003756|GO:0050451|GO:0050660|GO:0050661|GO:0055114 AFK25_03135 e10d095a65680a67e289e12bfc1e36b7 489 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 1 474 9.1E-135 T 11-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 AFK25_03135 e10d095a65680a67e289e12bfc1e36b7 489 SUPERFAMILY SSF51905 2 471 2.59E-55 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_03135 e10d095a65680a67e289e12bfc1e36b7 489 Pfam PF01593 Flavin containing amine oxidoreductase 3 470 2.5E-17 T 11-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AFK25_03135 e10d095a65680a67e289e12bfc1e36b7 489 Gene3D G3DSA:3.50.50.60 1 83 1.5E-15 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_03135 e10d095a65680a67e289e12bfc1e36b7 489 Gene3D G3DSA:3.50.50.60 183 305 1.5E-16 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_08750 a0c083344b50359f8efc3e1d4e2fda7f 394 Gene3D G3DSA:3.90.1150.10 25 385 1.5E-144 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_08750 a0c083344b50359f8efc3e1d4e2fda7f 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 114 135 1.1E-16 T 11-10-2018 AFK25_08750 a0c083344b50359f8efc3e1d4e2fda7f 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 161 185 1.1E-16 T 11-10-2018 AFK25_08750 a0c083344b50359f8efc3e1d4e2fda7f 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 197 220 1.1E-16 T 11-10-2018 AFK25_08750 a0c083344b50359f8efc3e1d4e2fda7f 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 228 252 1.1E-16 T 11-10-2018 AFK25_08750 a0c083344b50359f8efc3e1d4e2fda7f 394 PRINTS PR00753 1-aminocyclopropane-1-carboxylate synthase signature 92 112 1.1E-16 T 11-10-2018 AFK25_08750 a0c083344b50359f8efc3e1d4e2fda7f 394 SUPERFAMILY SSF53383 1 390 1.26E-120 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_08750 a0c083344b50359f8efc3e1d4e2fda7f 394 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 11-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AFK25_08750 a0c083344b50359f8efc3e1d4e2fda7f 394 Pfam PF00155 Aminotransferase class I and II 31 385 5.4E-83 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFK25_08750 a0c083344b50359f8efc3e1d4e2fda7f 394 Gene3D G3DSA:3.40.640.10 62 284 1.5E-144 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_14010 13ac0b9dea16ca9719b94663d85326eb 383 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 117 1.1E-41 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFK25_14010 13ac0b9dea16ca9719b94663d85326eb 383 Gene3D G3DSA:2.40.110.10 120 234 3.1E-49 T 11-10-2018 AFK25_14010 13ac0b9dea16ca9719b94663d85326eb 383 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFK25_14010 13ac0b9dea16ca9719b94663d85326eb 383 SUPERFAMILY SSF56645 2 242 9.03E-94 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFK25_14010 13ac0b9dea16ca9719b94663d85326eb 383 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 377 1.2E-54 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFK25_14010 13ac0b9dea16ca9719b94663d85326eb 383 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 216 1.6E-28 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFK25_14010 13ac0b9dea16ca9719b94663d85326eb 383 SUPERFAMILY SSF47203 227 381 1.77E-62 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFK25_14010 13ac0b9dea16ca9719b94663d85326eb 383 Gene3D G3DSA:1.20.140.10 235 382 1.2E-58 T 11-10-2018 AFK25_14010 13ac0b9dea16ca9719b94663d85326eb 383 Gene3D G3DSA:1.10.540.10 1 119 5.7E-46 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFK25_14010 13ac0b9dea16ca9719b94663d85326eb 383 PIRSF PIRSF016578 3 115 2.7E-5 T 11-10-2018 AFK25_14010 13ac0b9dea16ca9719b94663d85326eb 383 PIRSF PIRSF016578 125 367 2.3E-15 T 11-10-2018 AFK25_14010 13ac0b9dea16ca9719b94663d85326eb 383 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFK25_05405 7de58da7906edae36ca6695b3cd6b33c 69 Pfam PF01192 RNA polymerase Rpb6 9 60 5.4E-14 T 11-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFK25_05405 7de58da7906edae36ca6695b3cd6b33c 69 Hamap MF_00366 DNA-directed RNA polymerase subunit omega [rpoZ]. 1 62 14.601 T 11-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_05405 7de58da7906edae36ca6695b3cd6b33c 69 SUPERFAMILY SSF63562 1 67 2.44E-20 T 11-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFK25_05405 7de58da7906edae36ca6695b3cd6b33c 69 TIGRFAM TIGR00690 rpoZ: DNA-directed RNA polymerase, omega subunit 1 60 1.0E-19 T 11-10-2018 IPR003716 DNA-directed RNA polymerase, omega subunit GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_05405 7de58da7906edae36ca6695b3cd6b33c 69 SMART SM01409 8 61 4.1E-14 T 11-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFK25_05405 7de58da7906edae36ca6695b3cd6b33c 69 Gene3D G3DSA:3.90.940.10 1 69 8.4E-18 T 11-10-2018 IPR012293 RNA polymerase subunit, RPB6/omega GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AFK25_06860 b485e8ad9c22c17414ba7e5452a41f97 444 ProSitePatterns PS00180 Glutamine synthetase signature 1. 52 70 - T 11-10-2018 IPR027302 Glutamine synthetase, N-terminal conserved site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AFK25_06860 b485e8ad9c22c17414ba7e5452a41f97 444 Gene3D G3DSA:3.10.20.70 2 107 7.3E-47 T 11-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFK25_06860 b485e8ad9c22c17414ba7e5452a41f97 444 Pfam PF00120 Glutamine synthetase, catalytic domain 106 440 8.8E-145 T 11-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFK25_06860 b485e8ad9c22c17414ba7e5452a41f97 444 SUPERFAMILY SSF55931 105 442 2.45E-133 T 11-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFK25_06860 b485e8ad9c22c17414ba7e5452a41f97 444 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 7 441 6.0E-191 T 11-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFK25_06860 b485e8ad9c22c17414ba7e5452a41f97 444 SUPERFAMILY SSF54368 5 104 3.27E-36 T 11-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFK25_06860 b485e8ad9c22c17414ba7e5452a41f97 444 Gene3D G3DSA:3.30.590.10 108 444 1.6E-150 T 11-10-2018 AFK25_06860 b485e8ad9c22c17414ba7e5452a41f97 444 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 17 99 9.5E-34 T 11-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AFK25_06860 b485e8ad9c22c17414ba7e5452a41f97 444 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 234 249 - T 11-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AFK25_06860 b485e8ad9c22c17414ba7e5452a41f97 444 ProSitePatterns PS00182 Glutamine synthetase class-I adenylation site. 361 373 - T 11-10-2018 IPR001637 Glutamine synthetase class-I, adenylation site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFK25_06860 b485e8ad9c22c17414ba7e5452a41f97 444 SMART SM01230 105 354 2.6E-143 T 11-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFK25_05950 798052796f66f38fb465a4336d9e21e1 349 Gene3D G3DSA:3.30.360.10 129 325 6.2E-148 T 11-10-2018 AFK25_05950 798052796f66f38fb465a4336d9e21e1 349 SMART SM00859 7 122 1.3E-43 T 11-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFK25_05950 798052796f66f38fb465a4336d9e21e1 349 Gene3D G3DSA:3.40.50.720 8 339 6.2E-148 T 11-10-2018 AFK25_05950 798052796f66f38fb465a4336d9e21e1 349 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 5 342 39.311 T 11-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFK25_05950 798052796f66f38fb465a4336d9e21e1 349 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 8 120 2.1E-34 T 11-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFK25_05950 798052796f66f38fb465a4336d9e21e1 349 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 140 328 1.2E-60 T 11-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFK25_05950 798052796f66f38fb465a4336d9e21e1 349 SUPERFAMILY SSF51735 6 158 1.13E-51 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_05950 798052796f66f38fb465a4336d9e21e1 349 TIGRFAM TIGR01296 asd_B: aspartate-semialdehyde dehydrogenase 7 343 4.0E-163 T 11-10-2018 IPR005986 Aspartate-semialdehyde dehydrogenase, beta-type GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFK25_05950 798052796f66f38fb465a4336d9e21e1 349 PIRSF PIRSF000148 5 347 3.1E-136 T 11-10-2018 AFK25_05950 798052796f66f38fb465a4336d9e21e1 349 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 238 252 - T 11-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFK25_05950 798052796f66f38fb465a4336d9e21e1 349 SUPERFAMILY SSF55347 130 329 2.33E-77 T 11-10-2018 AFK25_13340 edcf3ebd6c0c1647637460d001c5a2b5 741 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 215 225 - T 11-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site AFK25_13340 edcf3ebd6c0c1647637460d001c5a2b5 741 PRINTS PR00723 Subtilisin serine protease family (S8) signature 406 422 1.9E-9 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related AFK25_13340 edcf3ebd6c0c1647637460d001c5a2b5 741 PRINTS PR00723 Subtilisin serine protease family (S8) signature 249 262 1.9E-9 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related AFK25_13340 edcf3ebd6c0c1647637460d001c5a2b5 741 PRINTS PR00723 Subtilisin serine protease family (S8) signature 210 229 1.9E-9 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related AFK25_13340 edcf3ebd6c0c1647637460d001c5a2b5 741 SUPERFAMILY SSF52743 206 467 3.67E-68 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFK25_13340 edcf3ebd6c0c1647637460d001c5a2b5 741 Gene3D G3DSA:3.40.50.200 198 473 3.5E-71 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFK25_13340 edcf3ebd6c0c1647637460d001c5a2b5 741 Pfam PF00082 Subtilase family 212 445 7.1E-35 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFK25_13340 edcf3ebd6c0c1647637460d001c5a2b5 741 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 407 417 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AFK25_13340 edcf3ebd6c0c1647637460d001c5a2b5 741 Pfam PF00395 S-layer homology domain 683 723 1.5E-9 T 11-10-2018 IPR001119 S-layer homology domain AFK25_13340 edcf3ebd6c0c1647637460d001c5a2b5 741 Pfam PF00395 S-layer homology domain 561 602 1.7E-12 T 11-10-2018 IPR001119 S-layer homology domain AFK25_13340 edcf3ebd6c0c1647637460d001c5a2b5 741 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 253 263 - T 11-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site AFK25_03290 b35842a9d6cfdf7ec10a97004dfb5cd0 504 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 496 171.069 T 11-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 AFK25_03290 b35842a9d6cfdf7ec10a97004dfb5cd0 504 Gene3D G3DSA:3.40.50.300 5 248 6.3E-54 T 11-10-2018 AFK25_03290 b35842a9d6cfdf7ec10a97004dfb5cd0 504 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 7 231 1.7E-20 T 11-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AFK25_03290 b35842a9d6cfdf7ec10a97004dfb5cd0 504 Gene3D G3DSA:3.40.50.880 254 439 1.5E-19 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_03290 b35842a9d6cfdf7ec10a97004dfb5cd0 504 SUPERFAMILY SSF52317 257 449 2.82E-32 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_03290 b35842a9d6cfdf7ec10a97004dfb5cd0 504 SUPERFAMILY SSF52540 7 232 5.67E-51 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_03290 b35842a9d6cfdf7ec10a97004dfb5cd0 504 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 256 441 3.3E-50 T 11-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 AFK25_03290 b35842a9d6cfdf7ec10a97004dfb5cd0 504 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 7 488 5.3E-166 T 11-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 3 89 1.4E-6 T 11-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 Gene3D G3DSA:1.10.10.60 617 685 2.5E-17 T 11-10-2018 AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 SMART SM00382 388 532 3.4E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 SUPERFAMILY SSF51735 1 110 1.37E-14 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 455 470 - T 11-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 Gene3D G3DSA:3.40.50.720 2 111 2.1E-6 T 11-10-2018 AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 SUPERFAMILY SSF52540 367 606 8.62E-70 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 663 683 1.7E-10 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 646 663 1.7E-10 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 Gene3D G3DSA:3.40.50.300 355 539 8.4E-66 T 11-10-2018 AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 SUPERFAMILY SSF55785 217 336 1.92E-14 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 SUPERFAMILY SSF55785 120 214 3.84E-16 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 SUPERFAMILY SSF46689 582 683 1.12E-13 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 Pfam PF00989 PAS fold 237 339 2.9E-14 T 11-10-2018 IPR013767 PAS fold GO:0006355 AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 Pfam PF00989 PAS fold 121 218 7.1E-12 T 11-10-2018 IPR013767 PAS fold GO:0006355 AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 Pfam PF00158 Sigma-54 interaction domain 368 535 2.7E-68 T 11-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 235 349 3.1E-17 T 11-10-2018 IPR000014 PAS domain AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 118 227 1.1E-11 T 11-10-2018 IPR000014 PAS domain AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 Gene3D G3DSA:3.30.450.20 223 339 2.6E-18 T 11-10-2018 AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 Gene3D G3DSA:3.30.450.20 112 219 2.3E-20 T 11-10-2018 AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 SMART SM00091 236 301 1.2E-4 T 11-10-2018 IPR000014 PAS domain AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 SMART SM00091 117 183 7.7E-10 T 11-10-2018 IPR000014 PAS domain AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 392 405 - T 11-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 Gene3D G3DSA:1.10.8.60 540 606 7.2E-23 T 11-10-2018 AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 582 591 - T 11-10-2018 IPR025944 Sigma-54 interaction domain, conserved site AFK25_09780 b1c5bcff21f4d734a1caf8dc446ddc5a 688 Pfam PF02954 Bacterial regulatory protein, Fis family 640 680 1.6E-14 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFK25_01440 2017834cd56182956459641185dcbb41 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 120 144 7.2E-98 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01440 2017834cd56182956459641185dcbb41 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 457 478 7.2E-98 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01440 2017834cd56182956459641185dcbb41 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 320 335 7.2E-98 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01440 2017834cd56182956459641185dcbb41 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 344 365 7.2E-98 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01440 2017834cd56182956459641185dcbb41 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 274 295 7.2E-98 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01440 2017834cd56182956459641185dcbb41 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 223 242 7.2E-98 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01440 2017834cd56182956459641185dcbb41 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 379 397 7.2E-98 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01440 2017834cd56182956459641185dcbb41 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 407 426 7.2E-98 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01440 2017834cd56182956459641185dcbb41 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 46 71 7.2E-98 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01440 2017834cd56182956459641185dcbb41 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 93 116 7.2E-98 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01440 2017834cd56182956459641185dcbb41 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 162 174 7.2E-98 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01440 2017834cd56182956459641185dcbb41 658 PRINTS PR01165 Cytochrome c oxidase subunit I signature 194 212 7.2E-98 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01440 2017834cd56182956459641185dcbb41 658 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 276 330 - T 11-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01440 2017834cd56182956459641185dcbb41 658 Gene3D G3DSA:1.20.210.10 29 560 4.5E-197 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01440 2017834cd56182956459641185dcbb41 658 SUPERFAMILY SSF81442 44 553 2.22E-178 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01440 2017834cd56182956459641185dcbb41 658 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 55 501 5.0E-144 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01440 2017834cd56182956459641185dcbb41 658 TIGRFAM TIGR02882 QoxB: cytochrome aa3 quinol oxidase, subunit I 4 644 0.0 T 11-10-2018 IPR014233 Quinol oxidase subunit I GO:0005507|GO:0016021|GO:0016682|GO:0020037|GO:0055114 AFK25_09890 60e873c478290cc2c6c07fd8c7cf22a5 68 Pfam PF06686 Stage III sporulation protein AC/AD protein family 8 62 9.4E-16 T 11-10-2018 IPR025664 Stage III sporulation protein AC/AD family AFK25_09890 60e873c478290cc2c6c07fd8c7cf22a5 68 TIGRFAM TIGR02848 spore_III_AC: stage III sporulation protein AC 3 66 4.8E-30 T 11-10-2018 IPR009570 Stage III sporulation protein AC AFK25_03215 4e4d28c6feaef01fb3ec24a4d672718f 120 Pfam PF01257 Thioredoxin-like [2Fe-2S] ferredoxin 9 84 2.4E-7 T 11-10-2018 AFK25_03215 4e4d28c6feaef01fb3ec24a4d672718f 120 Gene3D G3DSA:3.40.30.10 9 104 2.3E-24 T 11-10-2018 AFK25_03215 4e4d28c6feaef01fb3ec24a4d672718f 120 SUPERFAMILY SSF52833 10 103 1.57E-21 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_00355 0af17823b10d47417b56666798b0d356 247 SUPERFAMILY SSF53300 133 228 5.64E-12 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFK25_00355 0af17823b10d47417b56666798b0d356 247 Pfam PF00092 von Willebrand factor type A domain 2 78 1.5E-7 T 11-10-2018 IPR002035 von Willebrand factor, type A AFK25_00355 0af17823b10d47417b56666798b0d356 247 Pfam PF13519 von Willebrand factor type A domain 135 227 1.9E-7 T 11-10-2018 IPR002035 von Willebrand factor, type A AFK25_00355 0af17823b10d47417b56666798b0d356 247 SUPERFAMILY SSF53300 2 78 3.18E-10 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFK25_00355 0af17823b10d47417b56666798b0d356 247 Gene3D G3DSA:3.40.50.410 1 235 1.0E-58 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFK25_00705 80051e9441f9152dcfe586be2a2b11f5 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 172 195 1.7E-100 T 11-10-2018 AFK25_00705 80051e9441f9152dcfe586be2a2b11f5 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 309 331 1.7E-100 T 11-10-2018 AFK25_00705 80051e9441f9152dcfe586be2a2b11f5 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 18 36 1.7E-100 T 11-10-2018 AFK25_00705 80051e9441f9152dcfe586be2a2b11f5 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 67 87 1.7E-100 T 11-10-2018 AFK25_00705 80051e9441f9152dcfe586be2a2b11f5 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 364 382 1.7E-100 T 11-10-2018 AFK25_00705 80051e9441f9152dcfe586be2a2b11f5 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 109 132 1.7E-100 T 11-10-2018 AFK25_00705 80051e9441f9152dcfe586be2a2b11f5 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 146 171 1.7E-100 T 11-10-2018 AFK25_00705 80051e9441f9152dcfe586be2a2b11f5 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 269 288 1.7E-100 T 11-10-2018 AFK25_00705 80051e9441f9152dcfe586be2a2b11f5 430 PRINTS PR00303 Preprotein translocase SecY subunit signature 398 416 1.7E-100 T 11-10-2018 AFK25_00705 80051e9441f9152dcfe586be2a2b11f5 430 ProSitePatterns PS00756 Protein secY signature 2. 165 182 - T 11-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFK25_00705 80051e9441f9152dcfe586be2a2b11f5 430 PIRSF PIRSF004557 1 430 2.9E-131 T 11-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFK25_00705 80051e9441f9152dcfe586be2a2b11f5 430 Gene3D G3DSA:1.10.3370.10 1 425 2.8E-162 T 11-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFK25_00705 80051e9441f9152dcfe586be2a2b11f5 430 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 15 425 6.4E-150 T 11-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFK25_00705 80051e9441f9152dcfe586be2a2b11f5 430 Pfam PF00344 SecY translocase 68 413 5.0E-116 T 11-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFK25_00705 80051e9441f9152dcfe586be2a2b11f5 430 Hamap MF_01465 Protein translocase subunit SecY [secY]. 5 429 29.106 T 11-10-2018 IPR026593 Protein translocase subunit SecY AFK25_00705 80051e9441f9152dcfe586be2a2b11f5 430 ProSitePatterns PS00755 Protein secY signature 1. 68 87 - T 11-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFK25_00705 80051e9441f9152dcfe586be2a2b11f5 430 SUPERFAMILY SSF103491 1 420 4.71E-133 T 11-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 SUPERFAMILY SSF51246 341 460 4.03E-38 T 11-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 SUPERFAMILY SSF56059 88 330 2.65E-66 T 11-10-2018 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 Gene3D G3DSA:3.10.600.10 463 505 2.0E-5 T 11-10-2018 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 SUPERFAMILY SSF51230 1068 1145 8.64E-23 T 11-10-2018 IPR011053 Single hybrid motif AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 Pfam PF00289 Biotin carboxylase, N-terminal domain 6 114 9.8E-43 T 11-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 TIGRFAM TIGR01235 pyruv_carbox: pyruvate carboxylase 8 1145 0.0 T 11-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 Gene3D G3DSA:1.10.472.90 819 943 1.3E-297 T 11-10-2018 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 120 326 4.4E-78 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 Gene3D G3DSA:3.20.20.70 514 818 1.3E-297 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 SUPERFAMILY SSF89000 834 1011 1.37E-61 T 11-10-2018 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 158 172 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 Gene3D G3DSA:2.40.50.100 1069 1147 1.1E-25 T 11-10-2018 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 Gene3D G3DSA:1.10.10.2790 944 979 1.3E-297 T 11-10-2018 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 Pfam PF02785 Biotin carboxylase C-terminal domain 346 453 1.9E-32 T 11-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 Pfam PF02436 Conserved carboxylase domain 829 1029 3.7E-80 T 11-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 Gene3D G3DSA:3.10.600.10 507 1061 1.3E-297 T 11-10-2018 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 Pfam PF00364 Biotin-requiring enzyme 1079 1145 5.6E-18 T 11-10-2018 IPR000089 Biotin/lipoyl attachment AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 SMART SM00878 346 453 8.1E-52 T 11-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 290 297 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 SUPERFAMILY SSF51569 526 837 5.31E-88 T 11-10-2018 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 Pfam PF00682 HMGL-like 534 806 4.3E-29 T 11-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 SUPERFAMILY SSF52440 3 117 2.3E-45 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 PIRSF PIRSF001594 1 1147 0.0 T 11-10-2018 IPR005930 Pyruvate carboxylase GO:0004736|GO:0005524|GO:0006090|GO:0006094|GO:0009374 KEGG: 00020+6.4.1.1|KEGG: 00620+6.4.1.1|KEGG: 00720+6.4.1.1|MetaCyc: PWY-5750|MetaCyc: PWY-6142|MetaCyc: PWY-6146|Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 AFK25_05000 7f993826d31e6ccb9ef790d9978713b5 1148 Gene3D G3DSA:3.30.470.130 1 461 5.9E-197 T 11-10-2018 AFK25_09315 d19b6dafbb9988fd45aed31036f90b68 195 SUPERFAMILY SSF46785 85 158 6.53E-26 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_09315 d19b6dafbb9988fd45aed31036f90b68 195 Hamap MF_01804 Segregation and condensation protein B [scpB]. 3 182 35.585 T 11-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 AFK25_09315 d19b6dafbb9988fd45aed31036f90b68 195 Pfam PF04079 Segregation and condensation complex subunit ScpB 7 167 1.4E-59 T 11-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 AFK25_09315 d19b6dafbb9988fd45aed31036f90b68 195 PIRSF PIRSF019345 1 195 2.8E-57 T 11-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 AFK25_09315 d19b6dafbb9988fd45aed31036f90b68 195 Gene3D G3DSA:1.10.10.10 83 179 1.6E-41 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_09315 d19b6dafbb9988fd45aed31036f90b68 195 Gene3D G3DSA:1.10.10.10 2 82 1.9E-26 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_09315 d19b6dafbb9988fd45aed31036f90b68 195 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 7 188 4.3E-56 T 11-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 AFK25_09315 d19b6dafbb9988fd45aed31036f90b68 195 SUPERFAMILY SSF46785 3 80 3.81E-13 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_00465 86517ff8af8d64d988c596daba214495 810 SMART SM01086 714 803 5.0E-39 T 11-10-2018 IPR019489 Clp ATPase, C-terminal AFK25_00465 86517ff8af8d64d988c596daba214495 810 SUPERFAMILY SSF81923 5 146 2.51E-33 T 11-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFK25_00465 86517ff8af8d64d988c596daba214495 810 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 205 317 1.8E-13 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFK25_00465 86517ff8af8d64d988c596daba214495 810 Gene3D G3DSA:3.40.50.300 344 468 1.9E-43 T 11-10-2018 AFK25_00465 86517ff8af8d64d988c596daba214495 810 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 541 559 4.5E-43 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_00465 86517ff8af8d64d988c596daba214495 810 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 648 662 4.5E-43 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_00465 86517ff8af8d64d988c596daba214495 810 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 615 633 4.5E-43 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_00465 86517ff8af8d64d988c596daba214495 810 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 586 604 4.5E-43 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_00465 86517ff8af8d64d988c596daba214495 810 SUPERFAMILY SSF52540 161 468 1.68E-78 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_00465 86517ff8af8d64d988c596daba214495 810 Gene3D G3DSA:3.40.50.300 152 343 5.5E-72 T 11-10-2018 AFK25_00465 86517ff8af8d64d988c596daba214495 810 SMART SM00382 537 715 4.5E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_00465 86517ff8af8d64d988c596daba214495 810 SMART SM00382 200 345 3.4E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_00465 86517ff8af8d64d988c596daba214495 810 Gene3D G3DSA:3.40.50.300 469 713 6.6E-104 T 11-10-2018 AFK25_00465 86517ff8af8d64d988c596daba214495 810 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 571 589 - T 11-10-2018 IPR028299 ClpA/B, conserved site 2 AFK25_00465 86517ff8af8d64d988c596daba214495 810 Gene3D G3DSA:1.10.8.60 714 809 2.1E-30 T 11-10-2018 AFK25_00465 86517ff8af8d64d988c596daba214495 810 Gene3D G3DSA:1.10.1780.10 1 150 1.9E-63 T 11-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFK25_00465 86517ff8af8d64d988c596daba214495 810 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 295 307 - T 11-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 AFK25_00465 86517ff8af8d64d988c596daba214495 810 SUPERFAMILY SSF52540 486 802 1.7E-86 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_00465 86517ff8af8d64d988c596daba214495 810 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 69 2.4E-18 T 11-10-2018 IPR004176 Clp, N-terminal AFK25_00465 86517ff8af8d64d988c596daba214495 810 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 93 143 2.0E-18 T 11-10-2018 IPR004176 Clp, N-terminal AFK25_00465 86517ff8af8d64d988c596daba214495 810 Pfam PF02151 UvrB/uvrC motif 417 452 1.3E-5 T 11-10-2018 IPR001943 UVR domain GO:0005515 AFK25_00465 86517ff8af8d64d988c596daba214495 810 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 714 793 1.6E-27 T 11-10-2018 IPR019489 Clp ATPase, C-terminal AFK25_00465 86517ff8af8d64d988c596daba214495 810 Pfam PF07724 AAA domain (Cdc48 subfamily) 536 708 4.7E-59 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFK25_05255 11f9f841508e3a20132f546d922cd11d 426 Pfam PF02491 SHS2 domain inserted in FTSA 81 160 6.4E-29 T 11-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 AFK25_05255 11f9f841508e3a20132f546d922cd11d 426 Hamap MF_02033 Cell division protein FtsA [ftsA]. 3 425 31.178 T 11-10-2018 IPR020823 Cell division protein FtsA AFK25_05255 11f9f841508e3a20132f546d922cd11d 426 SMART SM00842 7 194 1.6E-95 T 11-10-2018 IPR003494 SHS2 domain inserted in FtsA GO:0005515|GO:0051301 AFK25_05255 11f9f841508e3a20132f546d922cd11d 426 Gene3D G3DSA:3.30.420.40 195 349 3.2E-117 T 11-10-2018 AFK25_05255 11f9f841508e3a20132f546d922cd11d 426 SUPERFAMILY SSF53067 5 194 7.78E-60 T 11-10-2018 AFK25_05255 11f9f841508e3a20132f546d922cd11d 426 Pfam PF14450 Cell division protein FtsA 205 366 2.4E-23 T 11-10-2018 AFK25_05255 11f9f841508e3a20132f546d922cd11d 426 Gene3D G3DSA:3.30.1490.110 83 167 3.2E-117 T 11-10-2018 AFK25_05255 11f9f841508e3a20132f546d922cd11d 426 PIRSF PIRSF003101 1 425 3.1E-151 T 11-10-2018 IPR020823 Cell division protein FtsA AFK25_05255 11f9f841508e3a20132f546d922cd11d 426 SUPERFAMILY SSF53067 197 368 1.3E-43 T 11-10-2018 AFK25_05255 11f9f841508e3a20132f546d922cd11d 426 Pfam PF14450 Cell division protein FtsA 9 188 1.1E-10 T 11-10-2018 AFK25_05255 11f9f841508e3a20132f546d922cd11d 426 TIGRFAM TIGR01174 ftsA: cell division protein FtsA 7 369 8.5E-131 T 11-10-2018 IPR020823 Cell division protein FtsA AFK25_05255 11f9f841508e3a20132f546d922cd11d 426 Gene3D G3DSA:3.90.640.10 233 298 3.2E-117 T 11-10-2018 AFK25_05255 11f9f841508e3a20132f546d922cd11d 426 Gene3D G3DSA:3.30.420.40 10 362 3.2E-117 T 11-10-2018 AFK25_11110 2680b1cea6ec92193a2e2b168692c9cf 308 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 230 246 - T 11-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFK25_11110 2680b1cea6ec92193a2e2b168692c9cf 308 Gene3D G3DSA:3.40.190.10 4 209 3.7E-85 T 11-10-2018 AFK25_11110 2680b1cea6ec92193a2e2b168692c9cf 308 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 3 294 38.787 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFK25_11110 2680b1cea6ec92193a2e2b168692c9cf 308 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 4 211 2.4E-81 T 11-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFK25_11110 2680b1cea6ec92193a2e2b168692c9cf 308 Gene3D G3DSA:3.30.160.40 220 303 3.9E-27 T 11-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFK25_11110 2680b1cea6ec92193a2e2b168692c9cf 308 PIRSF PIRSF001438 1 307 2.1E-122 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFK25_11110 2680b1cea6ec92193a2e2b168692c9cf 308 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 4 294 3.9E-113 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFK25_11110 2680b1cea6ec92193a2e2b168692c9cf 308 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 225 292 3.0E-18 T 11-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFK25_11110 2680b1cea6ec92193a2e2b168692c9cf 308 PRINTS PR00151 Porphobilinogen deaminase signature 229 246 1.1E-47 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFK25_11110 2680b1cea6ec92193a2e2b168692c9cf 308 PRINTS PR00151 Porphobilinogen deaminase signature 74 93 1.1E-47 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFK25_11110 2680b1cea6ec92193a2e2b168692c9cf 308 PRINTS PR00151 Porphobilinogen deaminase signature 122 139 1.1E-47 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFK25_11110 2680b1cea6ec92193a2e2b168692c9cf 308 PRINTS PR00151 Porphobilinogen deaminase signature 141 158 1.1E-47 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFK25_11110 2680b1cea6ec92193a2e2b168692c9cf 308 PRINTS PR00151 Porphobilinogen deaminase signature 43 63 1.1E-47 T 11-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFK25_11110 2680b1cea6ec92193a2e2b168692c9cf 308 Gene3D G3DSA:3.40.190.10 101 201 3.7E-85 T 11-10-2018 AFK25_11110 2680b1cea6ec92193a2e2b168692c9cf 308 SUPERFAMILY SSF53850 2 217 9.32E-84 T 11-10-2018 AFK25_11110 2680b1cea6ec92193a2e2b168692c9cf 308 SUPERFAMILY SSF54782 220 306 6.8E-23 T 11-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFK25_12270 2ce5064cbeb2cbebdf79d55b17a33be6 275 Gene3D G3DSA:3.40.50.1820 7 267 5.3E-75 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold AFK25_12270 2ce5064cbeb2cbebdf79d55b17a33be6 275 Hamap MF_01660 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase [menH]. 10 267 38.182 T 11-10-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 AFK25_12270 2ce5064cbeb2cbebdf79d55b17a33be6 275 SUPERFAMILY SSF53474 5 266 1.47E-62 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold AFK25_12270 2ce5064cbeb2cbebdf79d55b17a33be6 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 213 227 2.0E-9 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFK25_12270 2ce5064cbeb2cbebdf79d55b17a33be6 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 2.0E-9 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFK25_12270 2ce5064cbeb2cbebdf79d55b17a33be6 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 44 59 2.0E-9 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFK25_12270 2ce5064cbeb2cbebdf79d55b17a33be6 275 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 2.0E-9 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFK25_12270 2ce5064cbeb2cbebdf79d55b17a33be6 275 TIGRFAM TIGR03695 menH_SHCHC: 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase 19 266 3.9E-90 T 11-10-2018 IPR022485 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase GO:0009234|GO:0070205 KEGG: 00130+4.2.99.20|MetaCyc: PWY-5837 AFK25_12270 2ce5064cbeb2cbebdf79d55b17a33be6 275 Pfam PF00561 alpha/beta hydrolase fold 20 253 5.8E-31 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFK25_05935 6a39c3ce244fbd3b5e8a69d724da9f58 78 Pfam PF05239 PRC-barrel domain 2 77 1.9E-14 T 11-10-2018 IPR027275 PRC-barrel domain AFK25_05935 6a39c3ce244fbd3b5e8a69d724da9f58 78 SUPERFAMILY SSF50346 2 75 2.22E-11 T 11-10-2018 IPR011033 PRC-barrel-like superfamily AFK25_05935 6a39c3ce244fbd3b5e8a69d724da9f58 78 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 2 76 4.6E-29 T 11-10-2018 IPR014238 Sporulation protein YlmC/YmxH AFK25_05935 6a39c3ce244fbd3b5e8a69d724da9f58 78 Gene3D G3DSA:2.30.30.240 2 78 5.8E-8 T 11-10-2018 AFK25_09695 ed0e1acd77d8e9a3139a39f826165a60 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 119 144 8.8E-89 T 11-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFK25_09695 ed0e1acd77d8e9a3139a39f826165a60 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 167 195 8.8E-89 T 11-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFK25_09695 ed0e1acd77d8e9a3139a39f826165a60 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 4 27 8.8E-89 T 11-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFK25_09695 ed0e1acd77d8e9a3139a39f826165a60 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 66 95 8.8E-89 T 11-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFK25_09695 ed0e1acd77d8e9a3139a39f826165a60 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 357 379 8.8E-89 T 11-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFK25_09695 ed0e1acd77d8e9a3139a39f826165a60 469 PRINTS PR00076 6-phosphogluconate dehydrogenase signature 249 276 8.8E-89 T 11-10-2018 IPR006183 6-phosphogluconate dehydrogenase GO:0004616|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFK25_09695 ed0e1acd77d8e9a3139a39f826165a60 469 Gene3D G3DSA:1.20.5.320 436 469 2.7E-22 T 11-10-2018 AFK25_09695 ed0e1acd77d8e9a3139a39f826165a60 469 SUPERFAMILY SSF48179 176 468 2.68E-136 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFK25_09695 ed0e1acd77d8e9a3139a39f826165a60 469 Pfam PF00393 6-phosphogluconate dehydrogenase, C-terminal domain 178 467 5.7E-138 T 11-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFK25_09695 ed0e1acd77d8e9a3139a39f826165a60 469 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 5 168 5.0E-55 T 11-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 AFK25_09695 ed0e1acd77d8e9a3139a39f826165a60 469 SUPERFAMILY SSF51735 4 176 9.86E-57 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_09695 ed0e1acd77d8e9a3139a39f826165a60 469 Gene3D G3DSA:3.40.50.720 1 179 2.8E-61 T 11-10-2018 AFK25_09695 ed0e1acd77d8e9a3139a39f826165a60 469 TIGRFAM TIGR00873 gnd: 6-phosphogluconate dehydrogenase (decarboxylating) 5 468 8.8E-235 T 11-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFK25_09695 ed0e1acd77d8e9a3139a39f826165a60 469 Gene3D G3DSA:1.10.1040.10 180 435 9.4E-115 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFK25_09695 ed0e1acd77d8e9a3139a39f826165a60 469 PIRSF PIRSF000109 1 469 3.2E-246 T 11-10-2018 IPR006113 6-phosphogluconate dehydrogenase, decarboxylating GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFK25_09695 ed0e1acd77d8e9a3139a39f826165a60 469 ProSitePatterns PS00461 6-phosphogluconate dehydrogenase signature. 253 265 - T 11-10-2018 IPR006184 6-phosphogluconate-binding site GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFK25_09695 ed0e1acd77d8e9a3139a39f826165a60 469 SMART SM01350 178 468 2.5E-236 T 11-10-2018 IPR006114 6-phosphogluconate dehydrogenase, C-terminal GO:0004616|GO:0006098|GO:0055114 KEGG: 00030+1.1.1.44|KEGG: 00480+1.1.1.44|Reactome: R-HSA-71336 AFK25_10700 056eaa0346933d1ccd579b4734917f14 784 Gene3D G3DSA:3.40.50.300 512 740 9.0E-145 T 11-10-2018 AFK25_10700 056eaa0346933d1ccd579b4734917f14 784 SUPERFAMILY SSF52540 335 730 2.7E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_10700 056eaa0346933d1ccd579b4734917f14 784 Hamap MF_01488 ATP-dependent RecD-like DNA helicase [recD2]. 12 754 29.622 T 11-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 AFK25_10700 056eaa0346933d1ccd579b4734917f14 784 Pfam PF14490 Helix-hairpin-helix containing domain 156 247 1.4E-31 T 11-10-2018 IPR029493 RecD helicase-like helix-hairpin-helix domain AFK25_10700 056eaa0346933d1ccd579b4734917f14 784 Pfam PF13604 AAA domain 341 549 6.8E-53 T 11-10-2018 AFK25_10700 056eaa0346933d1ccd579b4734917f14 784 Gene3D G3DSA:2.30.30.940 598 677 9.0E-145 T 11-10-2018 AFK25_10700 056eaa0346933d1ccd579b4734917f14 784 Pfam PF13538 UvrD-like helicase C-terminal domain 676 724 5.3E-18 T 11-10-2018 IPR027785 UvrD-like helicase C-terminal domain AFK25_10700 056eaa0346933d1ccd579b4734917f14 784 TIGRFAM TIGR01448 recD_rel: helicase, RecD/TraA family 22 749 9.4E-264 T 11-10-2018 IPR006345 DNA helicase, RecD-like GO:0003677|GO:0032508|GO:0043141 AFK25_10700 056eaa0346933d1ccd579b4734917f14 784 Gene3D G3DSA:1.10.10.2220 198 295 5.4E-17 T 11-10-2018 AFK25_10700 056eaa0346933d1ccd579b4734917f14 784 Gene3D G3DSA:1.10.150.20 89 157 3.0E-7 T 11-10-2018 AFK25_10700 056eaa0346933d1ccd579b4734917f14 784 Gene3D G3DSA:3.40.50.300 334 746 9.0E-145 T 11-10-2018 AFK25_00405 f9049868c1501b899f3ef9f0a7695a78 289 SUPERFAMILY SSF56752 1 274 2.22E-77 T 11-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 AFK25_00405 f9049868c1501b899f3ef9f0a7695a78 289 Gene3D G3DSA:3.30.470.10 1 122 1.7E-38 T 11-10-2018 AFK25_00405 f9049868c1501b899f3ef9f0a7695a78 289 Gene3D G3DSA:3.20.10.10 123 272 1.4E-45 T 11-10-2018 AFK25_00405 f9049868c1501b899f3ef9f0a7695a78 289 Pfam PF01063 Amino-transferase class IV 29 249 7.2E-56 T 11-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 AFK25_00405 f9049868c1501b899f3ef9f0a7695a78 289 ProSitePatterns PS00770 Aminotransferases class-IV signature. 176 205 - T 11-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 AFK25_09350 301a8381b5245b2ab0e8b27fa3969792 358 SUPERFAMILY SSF53597 143 354 4.07E-64 T 11-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFK25_09350 301a8381b5245b2ab0e8b27fa3969792 358 Gene3D G3DSA:3.40.430.10 140 358 1.4E-79 T 11-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFK25_09350 301a8381b5245b2ab0e8b27fa3969792 358 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 49 87 - T 11-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 AFK25_09350 301a8381b5245b2ab0e8b27fa3969792 358 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 2 98 7.8E-21 T 11-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain AFK25_09350 301a8381b5245b2ab0e8b27fa3969792 358 SUPERFAMILY SSF53927 1 141 8.28E-47 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFK25_09350 301a8381b5245b2ab0e8b27fa3969792 358 Gene3D G3DSA:3.40.140.10 1 139 2.3E-46 T 11-10-2018 AFK25_09350 301a8381b5245b2ab0e8b27fa3969792 358 Pfam PF01872 RibD C-terminal domain 146 353 3.5E-61 T 11-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AFK25_09350 301a8381b5245b2ab0e8b27fa3969792 358 PIRSF PIRSF006769 1 357 1.4E-140 T 11-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 AFK25_09350 301a8381b5245b2ab0e8b27fa3969792 358 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 145 357 1.2E-76 T 11-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 AFK25_09350 301a8381b5245b2ab0e8b27fa3969792 358 TIGRFAM TIGR00326 eubact_ribD: riboflavin biosynthesis protein RibD 6 354 3.7E-132 T 11-10-2018 IPR004794 Riboflavin biosynthesis protein RibD GO:0008835|GO:0009231|GO:0055114 KEGG: 00740+3.5.4.26+1.1.1.193|MetaCyc: PWY-7991 AFK25_11680 ff94193b489cb4bf8e0c70c0a58db76f 315 Pfam PF01368 DHH family 18 156 4.7E-12 T 11-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFK25_11680 ff94193b489cb4bf8e0c70c0a58db76f 315 SUPERFAMILY SSF64182 16 304 2.35E-75 T 11-10-2018 IPR038763 DHH phosphoesterase superfamily AFK25_11680 ff94193b489cb4bf8e0c70c0a58db76f 315 Pfam PF02272 DHHA1 domain 180 311 4.3E-17 T 11-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 AFK25_11680 ff94193b489cb4bf8e0c70c0a58db76f 315 Gene3D G3DSA:3.10.310.30 202 315 5.9E-39 T 11-10-2018 AFK25_11680 ff94193b489cb4bf8e0c70c0a58db76f 315 Gene3D G3DSA:3.90.1640.10 3 198 1.2E-59 T 11-10-2018 AFK25_08920 2d514423f4139a4271d14507378523f0 389 ProSitePatterns PS00788 Chorismate synthase signature 2. 130 146 - T 11-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFK25_08920 2d514423f4139a4271d14507378523f0 389 PIRSF PIRSF001456 1 387 5.5E-134 T 11-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFK25_08920 2d514423f4139a4271d14507378523f0 389 Hamap MF_00300 Chorismate synthase [aroC]. 1 371 36.952 T 11-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFK25_08920 2d514423f4139a4271d14507378523f0 389 Pfam PF01264 Chorismate synthase 1 363 4.7E-126 T 11-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFK25_08920 2d514423f4139a4271d14507378523f0 389 Gene3D G3DSA:3.60.150.10 1 389 8.4E-158 T 11-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFK25_08920 2d514423f4139a4271d14507378523f0 389 TIGRFAM TIGR00033 aroC: chorismate synthase 1 369 3.0E-133 T 11-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFK25_08920 2d514423f4139a4271d14507378523f0 389 ProSitePatterns PS00789 Chorismate synthase signature 3. 338 354 - T 11-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFK25_08920 2d514423f4139a4271d14507378523f0 389 ProSitePatterns PS00787 Chorismate synthase signature 1. 7 22 - T 11-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFK25_08920 2d514423f4139a4271d14507378523f0 389 SUPERFAMILY SSF103263 1 388 1.31E-151 T 11-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AFK25_06680 15fc4dc8a8cce4a6586503fb855a08cc 121 ProSitePatterns PS00380 Rhodanese signature 1. 51 62 - T 11-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 AFK25_06680 15fc4dc8a8cce4a6586503fb855a08cc 121 SUPERFAMILY SSF52821 4 118 1.31E-36 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_06680 15fc4dc8a8cce4a6586503fb855a08cc 121 Pfam PF00581 Rhodanese-like domain 27 116 1.4E-22 T 11-10-2018 IPR001763 Rhodanese-like domain AFK25_06680 15fc4dc8a8cce4a6586503fb855a08cc 121 SMART SM00450 26 121 3.3E-28 T 11-10-2018 IPR001763 Rhodanese-like domain AFK25_06680 15fc4dc8a8cce4a6586503fb855a08cc 121 Gene3D G3DSA:3.40.250.10 20 121 1.2E-36 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 Gene3D G3DSA:3.30.450.20 140 261 4.3E-16 T 11-10-2018 AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 Gene3D G3DSA:1.10.287.130 493 570 2.8E-18 T 11-10-2018 AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 Pfam PF08448 PAS fold 150 254 2.7E-5 T 11-10-2018 IPR013656 PAS fold-4 AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 Gene3D G3DSA:3.30.450.20 374 492 5.2E-22 T 11-10-2018 AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 SUPERFAMILY SSF55785 12 129 8.55E-14 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 SUPERFAMILY SSF55785 250 354 2.09E-16 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 Pfam PF00512 His Kinase A (phospho-acceptor) domain 506 569 1.4E-13 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 Gene3D G3DSA:3.30.450.20 262 371 4.8E-16 T 11-10-2018 AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 SMART SM00387 612 718 5.3E-35 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 Pfam PF13188 PAS domain 265 317 1.7E-7 T 11-10-2018 IPR000014 PAS domain AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 Pfam PF13188 PAS domain 385 428 8.1E-9 T 11-10-2018 IPR000014 PAS domain AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 Pfam PF00989 PAS fold 24 87 1.1E-7 T 11-10-2018 IPR013767 PAS fold GO:0006355 AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 614 717 4.4E-25 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 PRINTS PR00344 Bacterial sensor protein C-terminal signature 649 663 7.1E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 PRINTS PR00344 Bacterial sensor protein C-terminal signature 667 677 7.1E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 PRINTS PR00344 Bacterial sensor protein C-terminal signature 678 696 7.1E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 PRINTS PR00344 Bacterial sensor protein C-terminal signature 702 715 7.1E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 SUPERFAMILY SSF47384 500 569 3.92E-13 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 SUPERFAMILY SSF55785 370 485 5.58E-18 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 SMART SM00091 144 210 7.3E-6 T 11-10-2018 IPR000014 PAS domain AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 SMART SM00091 23 91 1.4E-5 T 11-10-2018 IPR000014 PAS domain AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 SMART SM00091 265 330 2.5E-9 T 11-10-2018 IPR000014 PAS domain AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 SMART SM00091 385 451 3.7E-11 T 11-10-2018 IPR000014 PAS domain AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 Gene3D G3DSA:3.30.450.20 19 134 2.6E-14 T 11-10-2018 AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 SMART SM00388 504 571 6.9E-15 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 143 258 2.4E-11 T 11-10-2018 IPR000014 PAS domain AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 381 496 1.5E-14 T 11-10-2018 IPR000014 PAS domain AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 20 138 2.9E-12 T 11-10-2018 IPR000014 PAS domain AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 262 380 1.6E-9 T 11-10-2018 IPR000014 PAS domain AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 SUPERFAMILY SSF55874 563 716 1.83E-44 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 SUPERFAMILY SSF55785 129 251 1.45E-15 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_04355 0da3f7d0a28de544ad7873bf42401f63 721 Gene3D G3DSA:3.30.565.10 573 720 5.2E-48 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 SUPERFAMILY SSF81767 230 348 4.58E-43 T 11-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 Pfam PF07516 SecA Wing and Scaffold domain 573 773 6.3E-42 T 11-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 Gene3D G3DSA:3.40.50.300 397 570 0.0 T 11-10-2018 AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 777 18.237 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 496 2.6E-211 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 Gene3D G3DSA:3.90.1440.10 227 348 0.0 T 11-10-2018 AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 PRINTS PR00906 SecA protein signature 393 406 2.3E-62 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 PRINTS PR00906 SecA protein signature 319 341 2.3E-62 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 PRINTS PR00906 SecA protein signature 356 373 2.3E-62 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 PRINTS PR00906 SecA protein signature 61 85 2.3E-62 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 PRINTS PR00906 SecA protein signature 115 125 2.3E-62 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 PRINTS PR00906 SecA protein signature 168 188 2.3E-62 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 PRINTS PR00906 SecA protein signature 99 113 2.3E-62 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 Pfam PF01043 SecA preprotein cross-linking domain 236 338 1.6E-35 T 11-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 TIGRFAM TIGR04397 SecA2_Bac_anthr: accessory Sec system translocase SecA2 5 774 0.0 T 11-10-2018 IPR030908 Protein translocase subunit SecA 2, Bacillus anthracis-type AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 SUPERFAMILY SSF52540 7 395 1.56E-75 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 Gene3D G3DSA:1.10.3060.10 571 771 0.0 T 11-10-2018 AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 Gene3D G3DSA:1.10.1200.230 621 701 0.0 T 11-10-2018 AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 SMART SM00958 226 338 2.5E-59 T 11-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 SUPERFAMILY SSF52540 396 565 1.62E-44 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 Pfam PF07517 SecA DEAD-like domain 7 382 9.4E-119 T 11-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 ProSitePatterns PS01312 SecA family signature. 480 495 - T 11-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 SUPERFAMILY SSF81886 572 774 9.29E-49 T 11-10-2018 IPR036266 SecA, Wing/Scaffold superfamily AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 Gene3D G3DSA:3.40.50.300 14 396 0.0 T 11-10-2018 AFK25_13515 4262d3e52ba58441bb21f1bd8c9909b6 777 SMART SM00957 5 382 3.1E-253 T 11-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 AFK25_03450 dd06afa03e2625a5b9d8fad3c0f62b88 329 Gene3D G3DSA:1.10.240.10 183 293 5.9E-144 T 11-10-2018 AFK25_03450 dd06afa03e2625a5b9d8fad3c0f62b88 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 64 83 4.9E-30 T 11-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFK25_03450 dd06afa03e2625a5b9d8fad3c0f62b88 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 139 160 4.9E-30 T 11-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFK25_03450 dd06afa03e2625a5b9d8fad3c0f62b88 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 14 30 4.9E-30 T 11-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFK25_03450 dd06afa03e2625a5b9d8fad3c0f62b88 329 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 192 202 4.9E-30 T 11-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFK25_03450 dd06afa03e2625a5b9d8fad3c0f62b88 329 Pfam PF00579 tRNA synthetases class I (W and Y) 3 280 1.6E-85 T 11-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_03450 dd06afa03e2625a5b9d8fad3c0f62b88 329 Gene3D G3DSA:3.40.50.620 4 323 5.9E-144 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_03450 dd06afa03e2625a5b9d8fad3c0f62b88 329 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 10 19 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_03450 dd06afa03e2625a5b9d8fad3c0f62b88 329 TIGRFAM TIGR00233 trpS: tryptophan--tRNA ligase 2 324 3.7E-124 T 11-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AFK25_03450 dd06afa03e2625a5b9d8fad3c0f62b88 329 Hamap MF_00140_B Tryptophan--tRNA ligase [trpS]. 1 325 43.354 T 11-10-2018 IPR024109 Tryptophan-tRNA ligase, bacterial-type GO:0004830 KEGG: 00970+6.1.1.2|Reactome: R-HSA-379726 AFK25_03450 dd06afa03e2625a5b9d8fad3c0f62b88 329 SUPERFAMILY SSF52374 2 324 3.55E-102 T 11-10-2018 AFK25_08795 09079b38dbf42bb5514c6e0b028029c1 376 TIGRFAM TIGR03999 thiol_BshA: N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA 3 372 1.6E-173 T 11-10-2018 IPR023881 N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA GO:0016757|GO:0071793 AFK25_08795 09079b38dbf42bb5514c6e0b028029c1 376 Pfam PF00534 Glycosyl transferases group 1 186 350 1.8E-38 T 11-10-2018 IPR001296 Glycosyl transferase, family 1 AFK25_08795 09079b38dbf42bb5514c6e0b028029c1 376 Pfam PF13439 Glycosyltransferase Family 4 13 177 1.8E-25 T 11-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFK25_08795 09079b38dbf42bb5514c6e0b028029c1 376 Gene3D G3DSA:3.40.50.2000 22 369 7.4E-122 T 11-10-2018 AFK25_08795 09079b38dbf42bb5514c6e0b028029c1 376 SUPERFAMILY SSF53756 9 372 4.32E-86 T 11-10-2018 AFK25_08795 09079b38dbf42bb5514c6e0b028029c1 376 Gene3D G3DSA:3.40.50.2000 175 356 7.4E-122 T 11-10-2018 AFK25_08715 8220f1e5a36b4bcbe12ba06a99b57e93 216 Hamap MF_00942 Endonuclease III [nth]. 1 211 39.725 T 11-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 AFK25_08715 8220f1e5a36b4bcbe12ba06a99b57e93 216 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 35 170 4.5E-26 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFK25_08715 8220f1e5a36b4bcbe12ba06a99b57e93 216 SMART SM00525 188 208 3.7E-4 T 11-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 AFK25_08715 8220f1e5a36b4bcbe12ba06a99b57e93 216 SMART SM00478 39 187 4.2E-70 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFK25_08715 8220f1e5a36b4bcbe12ba06a99b57e93 216 TIGRFAM TIGR01083 nth: endonuclease III 5 196 2.6E-89 T 11-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 AFK25_08715 8220f1e5a36b4bcbe12ba06a99b57e93 216 SMART SM00278 110 129 0.0091 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFK25_08715 8220f1e5a36b4bcbe12ba06a99b57e93 216 ProSitePatterns PS00764 Endonuclease III iron-sulfur binding region signature. 189 205 - T 11-10-2018 IPR004035 Endonuclease III, iron-sulphur binding site Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 AFK25_08715 8220f1e5a36b4bcbe12ba06a99b57e93 216 Gene3D G3DSA:1.10.1670.10 16 205 6.4E-84 T 11-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AFK25_08715 8220f1e5a36b4bcbe12ba06a99b57e93 216 ProSitePatterns PS01155 Endonuclease III family signature. 103 132 - T 11-10-2018 IPR004036 Endonuclease III-like, conserved site-2 Reactome: R-HSA-110357 AFK25_08715 8220f1e5a36b4bcbe12ba06a99b57e93 216 Pfam PF10576 Iron-sulfur binding domain of endonuclease III 189 205 2.2E-5 T 11-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 AFK25_08715 8220f1e5a36b4bcbe12ba06a99b57e93 216 Pfam PF00633 Helix-hairpin-helix motif 101 128 6.7E-10 T 11-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 AFK25_08715 8220f1e5a36b4bcbe12ba06a99b57e93 216 Gene3D G3DSA:1.10.340.30 22 133 6.4E-84 T 11-10-2018 AFK25_08715 8220f1e5a36b4bcbe12ba06a99b57e93 216 PIRSF PIRSF001435 1 213 9.8E-61 T 11-10-2018 AFK25_08715 8220f1e5a36b4bcbe12ba06a99b57e93 216 SUPERFAMILY SSF48150 1 210 4.71E-77 T 11-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFK25_01735 4fa5ad7eaadad33e02501ab4c26913b0 359 Pfam PF14306 PUA-like domain 1 130 1.1E-46 T 11-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFK25_01735 4fa5ad7eaadad33e02501ab4c26913b0 359 Gene3D G3DSA:3.10.400.10 1 134 1.2E-45 T 11-10-2018 AFK25_01735 4fa5ad7eaadad33e02501ab4c26913b0 359 SUPERFAMILY SSF88697 2 131 1.39E-42 T 11-10-2018 IPR015947 PUA-like superfamily AFK25_01735 4fa5ad7eaadad33e02501ab4c26913b0 359 Pfam PF01747 ATP-sulfurylase 140 348 5.5E-93 T 11-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFK25_01735 4fa5ad7eaadad33e02501ab4c26913b0 359 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 1 353 47.669 T 11-10-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 AFK25_01735 4fa5ad7eaadad33e02501ab4c26913b0 359 Gene3D G3DSA:3.40.50.620 140 351 7.0E-95 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_01735 4fa5ad7eaadad33e02501ab4c26913b0 359 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 1 349 1.6E-129 T 11-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFK25_01735 4fa5ad7eaadad33e02501ab4c26913b0 359 SUPERFAMILY SSF52374 140 352 2.79E-86 T 11-10-2018 AFK25_00970 24d571ed5af945edb5d504d57588a1e5 144 Pfam PF01850 PIN domain 10 112 1.1E-10 T 11-10-2018 IPR002716 PIN domain AFK25_00970 24d571ed5af945edb5d504d57588a1e5 144 SUPERFAMILY SSF88723 12 115 1.51E-15 T 11-10-2018 IPR029060 PIN-like domain superfamily AFK25_00970 24d571ed5af945edb5d504d57588a1e5 144 Gene3D G3DSA:3.40.50.1010 6 137 1.1E-19 T 11-10-2018 AFK25_07500 ab204d77bfeee897efa44251bf60e9ea 66 SMART SM00357 3 66 7.4E-31 T 11-10-2018 IPR011129 Cold shock domain GO:0003676 AFK25_07500 ab204d77bfeee897efa44251bf60e9ea 66 PIRSF PIRSF002599 1 66 4.8E-24 T 11-10-2018 IPR012156 Cold shock, CspA GO:0003676 AFK25_07500 ab204d77bfeee897efa44251bf60e9ea 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 11-10-2018 IPR019844 Cold-shock conserved site AFK25_07500 ab204d77bfeee897efa44251bf60e9ea 66 Gene3D G3DSA:2.40.50.140 1 66 8.9E-31 T 11-10-2018 AFK25_07500 ab204d77bfeee897efa44251bf60e9ea 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 2.9E-30 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFK25_07500 ab204d77bfeee897efa44251bf60e9ea 66 SUPERFAMILY SSF50249 1 64 2.36E-24 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_07500 ab204d77bfeee897efa44251bf60e9ea 66 PRINTS PR00050 Cold shock protein signature 24 33 1.3E-18 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFK25_07500 ab204d77bfeee897efa44251bf60e9ea 66 PRINTS PR00050 Cold shock protein signature 4 19 1.3E-18 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFK25_07500 ab204d77bfeee897efa44251bf60e9ea 66 PRINTS PR00050 Cold shock protein signature 39 57 1.3E-18 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFK25_09775 e6f07d97f08b9bd7eed4c97b8c3b6b4f 300 SUPERFAMILY SSF53659 5 298 7.4E-64 T 11-10-2018 AFK25_09775 e6f07d97f08b9bd7eed4c97b8c3b6b4f 300 Gene3D G3DSA:3.40.718.10 2 300 1.7E-108 T 11-10-2018 AFK25_09775 e6f07d97f08b9bd7eed4c97b8c3b6b4f 300 PIRSF PIRSF000428 1 300 4.1E-85 T 11-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFK25_09775 e6f07d97f08b9bd7eed4c97b8c3b6b4f 300 TIGRFAM TIGR02706 P_butyryltrans: phosphate butyryltransferase 4 297 3.2E-128 T 11-10-2018 IPR014079 Phosphate butyryltransferase GO:0016740|GO:0019605|GO:0050182 KEGG: 00650+2.3.1.19 AFK25_09775 e6f07d97f08b9bd7eed4c97b8c3b6b4f 300 Pfam PF01515 Phosphate acetyl/butaryl transferase 5 295 5.2E-53 T 11-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFK25_12760 17ef7cd334a01af26204d820f5062e2c 342 Gene3D G3DSA:3.40.50.300 1 243 1.0E-79 T 11-10-2018 AFK25_12760 17ef7cd334a01af26204d820f5062e2c 342 Pfam PF09383 NIL domain 265 337 8.7E-23 T 11-10-2018 IPR018449 NIL domain AFK25_12760 17ef7cd334a01af26204d820f5062e2c 342 SUPERFAMILY SSF52540 1 240 8.96E-86 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_12760 17ef7cd334a01af26204d820f5062e2c 342 Gene3D G3DSA:3.30.70.260 244 341 5.0E-32 T 11-10-2018 AFK25_12760 17ef7cd334a01af26204d820f5062e2c 342 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_12760 17ef7cd334a01af26204d820f5062e2c 342 SMART SM00382 30 218 2.2E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_12760 17ef7cd334a01af26204d820f5062e2c 342 Pfam PF00005 ABC transporter 22 169 3.1E-37 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_12760 17ef7cd334a01af26204d820f5062e2c 342 SMART SM00930 263 338 3.9E-31 T 11-10-2018 IPR018449 NIL domain AFK25_12760 17ef7cd334a01af26204d820f5062e2c 342 SUPERFAMILY SSF55021 252 341 2.06E-25 T 11-10-2018 AFK25_03205 0a078b175ffbc5e5b62aa11c76a2f4c0 773 ProSitePatterns PS00707 Glycosyl hydrolases family 31 signature 2. 505 535 - T 11-10-2018 IPR030459 Glycosyl hydrolases family 31, conserved site AFK25_03205 0a078b175ffbc5e5b62aa11c76a2f4c0 773 Pfam PF13802 Galactose mutarotase-like 145 211 8.4E-23 T 11-10-2018 IPR025887 Glycoside hydrolase family 31, N-terminal domain AFK25_03205 0a078b175ffbc5e5b62aa11c76a2f4c0 773 Pfam PF17137 Domain of unknown function (DUF5110) 683 750 4.7E-14 T 11-10-2018 IPR033403 Domain of unknown function DUF5110 AFK25_03205 0a078b175ffbc5e5b62aa11c76a2f4c0 773 SUPERFAMILY SSF74650 21 237 3.45E-52 T 11-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 AFK25_03205 0a078b175ffbc5e5b62aa11c76a2f4c0 773 Gene3D G3DSA:2.60.40.1760 19 234 2.4E-50 T 11-10-2018 AFK25_03205 0a078b175ffbc5e5b62aa11c76a2f4c0 773 Pfam PF16338 Domain of unknown function (DUF4968) 34 123 4.9E-20 T 11-10-2018 IPR032513 Alpha-glucosidase, domain of unknown function DUF4968 AFK25_03205 0a078b175ffbc5e5b62aa11c76a2f4c0 773 SUPERFAMILY SSF51011 584 664 1.94E-25 T 11-10-2018 AFK25_03205 0a078b175ffbc5e5b62aa11c76a2f4c0 773 Gene3D G3DSA:3.20.20.80 237 585 1.1E-140 T 11-10-2018 AFK25_03205 0a078b175ffbc5e5b62aa11c76a2f4c0 773 Pfam PF01055 Glycosyl hydrolases family 31 230 668 1.0E-164 T 11-10-2018 IPR000322 Glycoside hydrolase family 31 GO:0004553|GO:0005975 AFK25_03205 0a078b175ffbc5e5b62aa11c76a2f4c0 773 SUPERFAMILY SSF51445 238 583 1.15E-93 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily AFK25_03205 0a078b175ffbc5e5b62aa11c76a2f4c0 773 ProSitePatterns PS00129 Glycosyl hydrolases family 31 active site. 400 407 - T 11-10-2018 IPR030458 Glycosyl hydrolases family 31, active site AFK25_03205 0a078b175ffbc5e5b62aa11c76a2f4c0 773 Gene3D G3DSA:2.60.40.1180 665 771 6.8E-14 T 11-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFK25_03205 0a078b175ffbc5e5b62aa11c76a2f4c0 773 Gene3D G3DSA:2.60.40.1180 586 663 5.6E-29 T 11-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFK25_11195 90bcc64d62c7f1c72e4233de9bdc3694 300 Gene3D G3DSA:3.30.470.10 1 126 7.0E-49 T 11-10-2018 AFK25_11195 90bcc64d62c7f1c72e4233de9bdc3694 300 Pfam PF01063 Amino-transferase class IV 32 258 9.4E-58 T 11-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 AFK25_11195 90bcc64d62c7f1c72e4233de9bdc3694 300 Gene3D G3DSA:3.20.10.10 127 289 1.3E-56 T 11-10-2018 AFK25_11195 90bcc64d62c7f1c72e4233de9bdc3694 300 ProSitePatterns PS00770 Aminotransferases class-IV signature. 185 214 - T 11-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 AFK25_11195 90bcc64d62c7f1c72e4233de9bdc3694 300 SUPERFAMILY SSF56752 4 284 4.32E-94 T 11-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 AFK25_11195 90bcc64d62c7f1c72e4233de9bdc3694 300 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 7 291 7.4E-102 T 11-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 AFK25_01830 d0fe13b77f965992afa2de2045cfe4cd 1045 Pfam PF13091 PLD-like domain 128 254 5.5E-13 T 11-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFK25_01830 d0fe13b77f965992afa2de2045cfe4cd 1045 SUPERFAMILY SSF56024 133 259 1.7E-8 T 11-10-2018 AFK25_01830 d0fe13b77f965992afa2de2045cfe4cd 1045 SMART SM00487 294 481 5.2E-15 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFK25_01830 d0fe13b77f965992afa2de2045cfe4cd 1045 Pfam PF00271 Helicase conserved C-terminal domain 535 626 6.7E-9 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_01830 d0fe13b77f965992afa2de2045cfe4cd 1045 Gene3D G3DSA:3.30.870.10 107 275 4.5E-31 T 11-10-2018 AFK25_01830 d0fe13b77f965992afa2de2045cfe4cd 1045 SMART SM00490 545 628 1.5E-7 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_01830 d0fe13b77f965992afa2de2045cfe4cd 1045 Gene3D G3DSA:3.40.50.300 276 462 2.4E-46 T 11-10-2018 AFK25_01830 d0fe13b77f965992afa2de2045cfe4cd 1045 Pfam PF04851 Type III restriction enzyme, res subunit 296 446 1.3E-35 T 11-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFK25_01830 d0fe13b77f965992afa2de2045cfe4cd 1045 Gene3D G3DSA:3.40.50.300 492 662 1.0E-37 T 11-10-2018 AFK25_01830 d0fe13b77f965992afa2de2045cfe4cd 1045 SUPERFAMILY SSF52540 343 647 1.59E-38 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_01830 d0fe13b77f965992afa2de2045cfe4cd 1045 Pfam PF11907 Domain of unknown function (DUF3427) 780 1043 1.4E-60 T 11-10-2018 IPR021835 Protein of unknown function DUF3427 AFK25_03950 7c2d1a6585b9acc6f8aaa7af3032ee72 326 SUPERFAMILY SSF52980 195 307 6.7E-16 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFK25_03950 7c2d1a6585b9acc6f8aaa7af3032ee72 326 PIRSF PIRSF031853 1 326 4.4E-123 T 11-10-2018 IPR016984 Uncharacterised conserved protein UCP031853 AFK25_03950 7c2d1a6585b9acc6f8aaa7af3032ee72 326 Pfam PF04471 Restriction endonuclease 191 302 1.1E-24 T 11-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 AFK25_04390 3723466ea10e00659168012065e71d46 264 Gene3D G3DSA:3.60.110.10 1 258 1.4E-95 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFK25_04390 3723466ea10e00659168012065e71d46 264 SUPERFAMILY SSF56317 1 260 5.76E-79 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFK25_04390 3723466ea10e00659168012065e71d46 264 Pfam PF00795 Carbon-nitrogen hydrolase 3 243 1.4E-53 T 11-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 AFK25_09165 c70fdf6bffac699ccb9548a4e9193053 195 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 9 179 4.0E-74 T 11-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 AFK25_09165 c70fdf6bffac699ccb9548a4e9193053 195 Gene3D G3DSA:1.20.1200.10 12 193 1.6E-71 T 11-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 AFK25_09165 c70fdf6bffac699ccb9548a4e9193053 195 SUPERFAMILY SSF89028 1 178 4.51E-66 T 11-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 AFK25_09165 c70fdf6bffac699ccb9548a4e9193053 195 TIGRFAM TIGR00636 PduO_Nterm: ATP:cob(I)alamin adenosyltransferase 4 178 1.3E-64 T 11-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 AFK25_09165 c70fdf6bffac699ccb9548a4e9193053 195 Pfam PF01923 Cobalamin adenosyltransferase 4 166 9.4E-60 T 11-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 AFK25_12090 dba3da883bd71d1f046a847a52671df1 401 ProSitePatterns PS00377 S-adenosylmethionine synthase signature 2. 272 280 - T 11-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFK25_12090 dba3da883bd71d1f046a847a52671df1 401 Hamap MF_00086 S-adenosylmethionine synthase [metK]. 3 396 61.307 T 11-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFK25_12090 dba3da883bd71d1f046a847a52671df1 401 PIRSF PIRSF000497 1 397 4.8E-182 T 11-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFK25_12090 dba3da883bd71d1f046a847a52671df1 401 Pfam PF00438 S-adenosylmethionine synthetase, N-terminal domain 5 102 4.5E-45 T 11-10-2018 IPR022628 S-adenosylmethionine synthetase, N-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFK25_12090 dba3da883bd71d1f046a847a52671df1 401 SUPERFAMILY SSF55973 246 394 7.46E-72 T 11-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFK25_12090 dba3da883bd71d1f046a847a52671df1 401 Gene3D G3DSA:3.30.300.10 12 283 1.7E-185 T 11-10-2018 AFK25_12090 dba3da883bd71d1f046a847a52671df1 401 SUPERFAMILY SSF55973 4 110 7.85E-49 T 11-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFK25_12090 dba3da883bd71d1f046a847a52671df1 401 Pfam PF02772 S-adenosylmethionine synthetase, central domain 127 244 8.9E-51 T 11-10-2018 IPR022629 S-adenosylmethionine synthetase, central domain GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFK25_12090 dba3da883bd71d1f046a847a52671df1 401 TIGRFAM TIGR01034 metK: methionine adenosyltransferase 6 394 2.1E-191 T 11-10-2018 IPR002133 S-adenosylmethionine synthetase GO:0004478|GO:0005524|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFK25_12090 dba3da883bd71d1f046a847a52671df1 401 SUPERFAMILY SSF55973 124 245 2.16E-54 T 11-10-2018 IPR022636 S-adenosylmethionine synthetase superfamily GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFK25_12090 dba3da883bd71d1f046a847a52671df1 401 Gene3D G3DSA:3.30.300.10 6 246 1.7E-185 T 11-10-2018 AFK25_12090 dba3da883bd71d1f046a847a52671df1 401 ProSitePatterns PS00376 S-adenosylmethionine synthase signature 1. 128 138 - T 11-10-2018 IPR022631 S-adenosylmethionine synthetase, conserved site GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFK25_12090 dba3da883bd71d1f046a847a52671df1 401 Gene3D G3DSA:3.30.300.10 103 388 1.7E-185 T 11-10-2018 AFK25_12090 dba3da883bd71d1f046a847a52671df1 401 Pfam PF02773 S-adenosylmethionine synthetase, C-terminal domain 246 385 1.9E-71 T 11-10-2018 IPR022630 S-adenosylmethionine synthetase, C-terminal GO:0004478|GO:0006556 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912|Reactome: R-HSA-156581 AFK25_05720 00978385c6b05646e614df3898178a3c 332 SUPERFAMILY SSF103039 47 232 3.14E-31 T 11-10-2018 IPR028976 CheC-like superfamily AFK25_05720 00978385c6b05646e614df3898178a3c 332 SUPERFAMILY SSF101801 251 328 3.4E-18 T 11-10-2018 IPR036429 SpoA-like superfamily AFK25_05720 00978385c6b05646e614df3898178a3c 332 Pfam PF02154 Flagellar motor switch protein FliM 40 230 1.1E-74 T 11-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 AFK25_05720 00978385c6b05646e614df3898178a3c 332 Gene3D G3DSA:2.30.330.10 239 330 3.1E-10 T 11-10-2018 IPR036429 SpoA-like superfamily AFK25_05720 00978385c6b05646e614df3898178a3c 332 TIGRFAM TIGR01397 fliM_switch: flagellar motor switch protein FliM 4 324 1.2E-112 T 11-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 AFK25_05720 00978385c6b05646e614df3898178a3c 332 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 253 324 1.1E-21 T 11-10-2018 IPR001543 Surface presentation of antigen (SpoA) AFK25_05720 00978385c6b05646e614df3898178a3c 332 Gene3D G3DSA:3.40.1550.10 46 231 7.3E-61 T 11-10-2018 IPR028976 CheC-like superfamily AFK25_05720 00978385c6b05646e614df3898178a3c 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 116 135 1.3E-28 T 11-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 AFK25_05720 00978385c6b05646e614df3898178a3c 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 91 107 1.3E-28 T 11-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 AFK25_05720 00978385c6b05646e614df3898178a3c 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 3 16 1.3E-28 T 11-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 AFK25_05720 00978385c6b05646e614df3898178a3c 332 PRINTS PR00955 Flagellar motor switch protein FliM signature 212 230 1.3E-28 T 11-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 AFK25_05720 00978385c6b05646e614df3898178a3c 332 PIRSF PIRSF002888 2 332 1.6E-115 T 11-10-2018 IPR001689 Flagellar motor switch protein FliM GO:0003774|GO:0009425|GO:0071973 AFK25_10705 1c4e8cc60dc55da776ca87de99d66cba 218 Pfam PF13414 TPR repeat 41 81 8.5E-9 T 11-10-2018 AFK25_10705 1c4e8cc60dc55da776ca87de99d66cba 218 Gene3D G3DSA:1.25.40.10 1 101 6.6E-29 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_10705 1c4e8cc60dc55da776ca87de99d66cba 218 Pfam PF13424 Tetratricopeptide repeat 137 200 6.8E-9 T 11-10-2018 AFK25_10705 1c4e8cc60dc55da776ca87de99d66cba 218 SMART SM00671 136 167 240.0 T 11-10-2018 IPR006597 Sel1-like repeat AFK25_10705 1c4e8cc60dc55da776ca87de99d66cba 218 SMART SM00671 170 201 7.4 T 11-10-2018 IPR006597 Sel1-like repeat AFK25_10705 1c4e8cc60dc55da776ca87de99d66cba 218 SMART SM00671 68 99 6.9 T 11-10-2018 IPR006597 Sel1-like repeat AFK25_10705 1c4e8cc60dc55da776ca87de99d66cba 218 SMART SM00028 170 203 4.6E-5 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_10705 1c4e8cc60dc55da776ca87de99d66cba 218 SMART SM00028 3 33 0.003 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_10705 1c4e8cc60dc55da776ca87de99d66cba 218 SMART SM00028 34 67 0.0018 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_10705 1c4e8cc60dc55da776ca87de99d66cba 218 SMART SM00028 68 101 0.0062 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_10705 1c4e8cc60dc55da776ca87de99d66cba 218 SMART SM00028 102 135 0.15 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_10705 1c4e8cc60dc55da776ca87de99d66cba 218 SMART SM00028 136 169 10.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_10705 1c4e8cc60dc55da776ca87de99d66cba 218 Pfam PF13181 Tetratricopeptide repeat 104 133 0.0094 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_10705 1c4e8cc60dc55da776ca87de99d66cba 218 Gene3D G3DSA:1.25.40.10 102 218 8.1E-25 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_10705 1c4e8cc60dc55da776ca87de99d66cba 218 Pfam PF00515 Tetratricopeptide repeat 3 33 3.7E-8 T 11-10-2018 IPR001440 Tetratricopeptide repeat 1 GO:0005515 AFK25_10705 1c4e8cc60dc55da776ca87de99d66cba 218 SUPERFAMILY SSF48452 3 208 2.09E-44 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 Gene3D G3DSA:3.20.20.80 470 944 1.0E-123 T 11-10-2018 AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 SUPERFAMILY SSF51445 403 946 3.79E-93 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 Gene3D G3DSA:2.60.40.10 1253 1334 4.7E-10 T 11-10-2018 IPR013783 Immunoglobulin-like fold AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 Gene3D G3DSA:2.60.40.10 1335 1424 6.9E-6 T 11-10-2018 IPR013783 Immunoglobulin-like fold AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 Gene3D G3DSA:2.60.40.1180 947 1034 1.1E-20 T 11-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 Gene3D G3DSA:2.60.40.10 242 338 1.5E-19 T 11-10-2018 IPR013783 Immunoglobulin-like fold AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 Gene3D G3DSA:2.60.40.10 136 238 1.8E-32 T 11-10-2018 IPR013783 Immunoglobulin-like fold AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 Gene3D G3DSA:2.60.40.10 339 462 2.9E-25 T 11-10-2018 IPR013783 Immunoglobulin-like fold AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 SMART SM00060 1040 1113 8.4E-4 T 11-10-2018 IPR003961 Fibronectin type III GO:0005515 AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 SMART SM00060 1247 1322 51.0 T 11-10-2018 IPR003961 Fibronectin type III GO:0005515 AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 Pfam PF00395 S-layer homology domain 1886 1931 1.7E-9 T 11-10-2018 IPR001119 S-layer homology domain AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 Pfam PF00395 S-layer homology domain 1827 1869 1.8E-14 T 11-10-2018 IPR001119 S-layer homology domain AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 Pfam PF00395 S-layer homology domain 1959 2002 2.6E-11 T 11-10-2018 IPR001119 S-layer homology domain AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 SMART SM00632 955 1036 4.9E-10 T 11-10-2018 IPR031319 Alpha-amylase, C-terminal domain Reactome: R-HSA-189085 AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 Pfam PF16561 Glycogen recognition site of AMP-activated protein kinase 44 129 1.3E-13 T 11-10-2018 IPR032640 AMP-activated protein kinase, glycogen-binding domain Reactome: R-HSA-1445148|Reactome: R-HSA-1632852|Reactome: R-HSA-2151209|Reactome: R-HSA-380972|Reactome: R-HSA-5628897|Reactome: R-HSA-6804756 AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 Gene3D G3DSA:2.60.40.10 1040 1125 7.3E-15 T 11-10-2018 IPR013783 Immunoglobulin-like fold AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 SMART SM01065 1336 1421 6.0E-5 T 11-10-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 SMART SM01065 41 126 0.17 T 11-10-2018 IPR002044 Carbohydrate binding module family 20 GO:2001070 AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 SUPERFAMILY SSF81296 49 131 1.17E-17 T 11-10-2018 IPR014756 Immunoglobulin E-set AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 SUPERFAMILY SSF49452 1336 1402 2.75E-6 T 11-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 SUPERFAMILY SSF51011 952 1032 2.8E-16 T 11-10-2018 AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 Pfam PF02903 Alpha amylase, N-terminal ig-like domain 366 444 2.1E-4 T 11-10-2018 IPR004185 Glycoside hydrolase, family 13, N-terminal Ig-like domain GO:0004553|GO:0005975 AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 SMART SM00642 482 942 5.5E-96 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 Pfam PF00128 Alpha amylase, catalytic domain 541 916 2.8E-63 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 SUPERFAMILY SSF49265 1035 1115 5.09E-9 T 11-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AFK25_13355 2f5e6353412d802cfc2c667ad4b39bc3 2015 Gene3D G3DSA:2.60.40.10 29 130 5.0E-23 T 11-10-2018 IPR013783 Immunoglobulin-like fold AFK25_07970 a588236f851d78ce5ba174665b2450aa 479 Gene3D G3DSA:3.30.565.10 318 477 1.7E-19 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_07970 a588236f851d78ce5ba174665b2450aa 479 Gene3D G3DSA:1.20.1480.50 162 257 1.4E-14 T 11-10-2018 AFK25_07970 a588236f851d78ce5ba174665b2450aa 479 SUPERFAMILY SSF158472 198 247 1.44E-11 T 11-10-2018 AFK25_07970 a588236f851d78ce5ba174665b2450aa 479 Pfam PF06580 Histidine kinase 266 344 1.9E-26 T 11-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 AFK25_07970 a588236f851d78ce5ba174665b2450aa 479 SMART SM00304 198 251 2.2E-10 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_07970 a588236f851d78ce5ba174665b2450aa 479 SUPERFAMILY SSF55874 320 468 1.06E-22 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_07970 a588236f851d78ce5ba174665b2450aa 479 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 365 469 1.2E-8 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_07970 a588236f851d78ce5ba174665b2450aa 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 397 411 1.1E-6 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_07970 a588236f851d78ce5ba174665b2450aa 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 428 446 1.1E-6 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_07970 a588236f851d78ce5ba174665b2450aa 479 PRINTS PR00344 Bacterial sensor protein C-terminal signature 455 468 1.1E-6 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_07970 a588236f851d78ce5ba174665b2450aa 479 SMART SM00387 356 471 3.2E-7 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_07970 a588236f851d78ce5ba174665b2450aa 479 Pfam PF00672 HAMP domain 199 247 2.8E-10 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_05905 9c31b659950ba9c551ae927eb18b510b 298 TIGRFAM TIGR00431 TruB: tRNA pseudouridine(55) synthase 1 215 5.9E-84 T 11-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_05905 9c31b659950ba9c551ae927eb18b510b 298 Hamap MF_01080 tRNA pseudouridine synthase B [truB]. 1 298 19.345 T 11-10-2018 IPR014780 tRNA pseudouridine synthase II, TruB GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_05905 9c31b659950ba9c551ae927eb18b510b 298 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 179 237 8.1E-13 T 11-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 AFK25_05905 9c31b659950ba9c551ae927eb18b510b 298 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 23 178 4.5E-56 T 11-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 AFK25_05905 9c31b659950ba9c551ae927eb18b510b 298 SUPERFAMILY SSF55120 1 232 4.96E-79 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_05905 9c31b659950ba9c551ae927eb18b510b 298 Gene3D G3DSA:3.30.2350.10 1 242 4.8E-90 T 11-10-2018 AFK25_14230 d604a8c8da5a9b7f693604df8844665d 321 Gene3D G3DSA:3.40.1190.20 2 320 3.5E-102 T 11-10-2018 IPR029056 Ribokinase-like AFK25_14230 d604a8c8da5a9b7f693604df8844665d 321 PRINTS PR00990 Ribokinase signature 221 232 5.0E-8 T 11-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFK25_14230 d604a8c8da5a9b7f693604df8844665d 321 PRINTS PR00990 Ribokinase signature 27 46 5.0E-8 T 11-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFK25_14230 d604a8c8da5a9b7f693604df8844665d 321 PRINTS PR00990 Ribokinase signature 182 197 5.0E-8 T 11-10-2018 IPR002139 Ribokinase/fructokinase GO:0016301 Reactome: R-HSA-71336 AFK25_14230 d604a8c8da5a9b7f693604df8844665d 321 Pfam PF00294 pfkB family carbohydrate kinase 6 307 9.1E-69 T 11-10-2018 IPR011611 Carbohydrate kinase PfkB AFK25_14230 d604a8c8da5a9b7f693604df8844665d 321 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 32 56 - T 11-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFK25_14230 d604a8c8da5a9b7f693604df8844665d 321 SUPERFAMILY SSF53613 2 315 7.17E-90 T 11-10-2018 IPR029056 Ribokinase-like AFK25_14230 d604a8c8da5a9b7f693604df8844665d 321 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 250 263 - T 11-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFK25_11925 5d377e2174653657cd8df16b191e0f33 201 Pfam PF14794 Domain of unknown function (DUF4479) 24 91 2.8E-25 T 11-10-2018 IPR027855 Domain of unknown function DUF4479 AFK25_11925 5d377e2174653657cd8df16b191e0f33 201 Gene3D G3DSA:3.30.1940.10 18 92 9.0E-78 T 11-10-2018 IPR037154 YtpR-like superfamily AFK25_11925 5d377e2174653657cd8df16b191e0f33 201 Gene3D G3DSA:2.40.50.140 5 199 9.0E-78 T 11-10-2018 AFK25_11925 5d377e2174653657cd8df16b191e0f33 201 SUPERFAMILY SSF50249 91 200 6.61E-34 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_11925 5d377e2174653657cd8df16b191e0f33 201 Pfam PF01588 Putative tRNA binding domain 96 197 8.4E-28 T 11-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 AFK25_12990 9c78b47c78ffc01d73af3d92c3b8911a 242 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 4 235 1.7E-86 T 11-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 AFK25_12990 9c78b47c78ffc01d73af3d92c3b8911a 242 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 3 239 37.27 T 11-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 AFK25_12990 9c78b47c78ffc01d73af3d92c3b8911a 242 Pfam PF00977 Histidine biosynthesis protein 4 232 1.1E-80 T 11-10-2018 IPR006062 Histidine biosynthesis GO:0000105 AFK25_12990 9c78b47c78ffc01d73af3d92c3b8911a 242 Gene3D G3DSA:3.20.20.70 1 242 9.8E-93 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_12990 9c78b47c78ffc01d73af3d92c3b8911a 242 SUPERFAMILY SSF51366 3 238 2.75E-74 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFK25_09655 a811735d4d0c3d3a4eb6d55a7aa67518 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 81 92 6.1E-27 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_09655 a811735d4d0c3d3a4eb6d55a7aa67518 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.1E-27 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_09655 a811735d4d0c3d3a4eb6d55a7aa67518 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 128 144 6.1E-27 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_09655 a811735d4d0c3d3a4eb6d55a7aa67518 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 175 192 6.1E-27 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_09655 a811735d4d0c3d3a4eb6d55a7aa67518 261 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 154 173 6.1E-27 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_09655 a811735d4d0c3d3a4eb6d55a7aa67518 261 Gene3D G3DSA:3.40.50.720 1 260 4.4E-64 T 11-10-2018 AFK25_09655 a811735d4d0c3d3a4eb6d55a7aa67518 261 Pfam PF00106 short chain dehydrogenase 6 192 4.3E-52 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_09655 a811735d4d0c3d3a4eb6d55a7aa67518 261 PIRSF PIRSF000126 1 257 6.4E-57 T 11-10-2018 AFK25_09655 a811735d4d0c3d3a4eb6d55a7aa67518 261 SUPERFAMILY SSF51735 1 252 5.49E-64 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_09655 a811735d4d0c3d3a4eb6d55a7aa67518 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 81 92 8.0E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_09655 a811735d4d0c3d3a4eb6d55a7aa67518 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 134 142 8.0E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_09655 a811735d4d0c3d3a4eb6d55a7aa67518 261 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 154 173 8.0E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_09655 a811735d4d0c3d3a4eb6d55a7aa67518 261 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 141 169 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFK25_11535 2deb705ae6f565a55648d73a5823eae5 284 Pfam PF08812 YtxC-like family 54 264 4.0E-56 T 11-10-2018 IPR014199 Sporulation protein YtxC AFK25_11535 2deb705ae6f565a55648d73a5823eae5 284 TIGRFAM TIGR02834 spo_ytxC: putative sporulation protein YtxC 36 265 1.2E-69 T 11-10-2018 IPR014199 Sporulation protein YtxC AFK25_11535 2deb705ae6f565a55648d73a5823eae5 284 PIRSF PIRSF012563 1 283 3.0E-87 T 11-10-2018 IPR014199 Sporulation protein YtxC AFK25_01910 b581d1920affdc1cd4cde5f3c53a77e9 362 Gene3D G3DSA:1.10.1670.10 22 225 6.4E-91 T 11-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AFK25_01910 b581d1920affdc1cd4cde5f3c53a77e9 362 Gene3D G3DSA:1.10.340.30 33 144 6.4E-91 T 11-10-2018 AFK25_01910 b581d1920affdc1cd4cde5f3c53a77e9 362 SMART SM00478 51 202 4.8E-49 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFK25_01910 b581d1920affdc1cd4cde5f3c53a77e9 362 TIGRFAM TIGR01084 mutY: A/G-specific adenine glycosylase 18 279 6.3E-107 T 11-10-2018 IPR005760 A/G-specific adenine glycosylase MutY GO:0006284|GO:0019104 AFK25_01910 b581d1920affdc1cd4cde5f3c53a77e9 362 SUPERFAMILY SSF55811 241 361 5.18E-24 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFK25_01910 b581d1920affdc1cd4cde5f3c53a77e9 362 SUPERFAMILY SSF48150 16 234 6.44E-75 T 11-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFK25_01910 b581d1920affdc1cd4cde5f3c53a77e9 362 Gene3D G3DSA:3.90.79.10 241 362 6.5E-28 T 11-10-2018 AFK25_01910 b581d1920affdc1cd4cde5f3c53a77e9 362 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 47 180 1.1E-17 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFK25_01910 b581d1920affdc1cd4cde5f3c53a77e9 362 Pfam PF14815 NUDIX domain 248 360 8.8E-23 T 11-10-2018 IPR029119 MutY, C-terminal Reactome: R-HSA-110330|Reactome: R-HSA-110331|Reactome: R-HSA-110357 AFK25_10425 7e44dc683f7961275bbe915bf7deef18 227 SMART SM00419 172 220 4.1E-9 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFK25_10425 7e44dc683f7961275bbe915bf7deef18 227 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 177 193 1.7E-7 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFK25_10425 7e44dc683f7961275bbe915bf7deef18 227 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 193 208 1.7E-7 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFK25_10425 7e44dc683f7961275bbe915bf7deef18 227 Gene3D G3DSA:1.10.10.10 148 227 4.8E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_10425 7e44dc683f7961275bbe915bf7deef18 227 SUPERFAMILY SSF46785 151 225 3.39E-19 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_10425 7e44dc683f7961275bbe915bf7deef18 227 Gene3D G3DSA:2.60.120.10 2 147 3.2E-36 T 11-10-2018 IPR014710 RmlC-like jelly roll fold AFK25_10425 7e44dc683f7961275bbe915bf7deef18 227 Pfam PF13545 Crp-like helix-turn-helix domain 153 225 1.0E-14 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFK25_10425 7e44dc683f7961275bbe915bf7deef18 227 SUPERFAMILY SSF51206 9 147 8.25E-37 T 11-10-2018 IPR018490 Cyclic nucleotide-binding-like AFK25_10425 7e44dc683f7961275bbe915bf7deef18 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 178 192 6.4E-5 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_10425 7e44dc683f7961275bbe915bf7deef18 227 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 192 208 6.4E-5 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_10425 7e44dc683f7961275bbe915bf7deef18 227 SMART SM00100 14 132 1.6E-24 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain AFK25_10425 7e44dc683f7961275bbe915bf7deef18 227 Pfam PF00027 Cyclic nucleotide-binding domain 33 116 2.1E-18 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain AFK25_08635 ec892a353893ca0e990887d20a60543d 373 Gene3D G3DSA:3.90.1510.10 42 273 1.3E-128 T 11-10-2018 IPR018193 Glycerate kinase, flavodoxin-like fold GO:0008887|GO:0031388 AFK25_08635 ec892a353893ca0e990887d20a60543d 373 TIGRFAM TIGR00045 TIGR00045: glycerate kinase 2 370 3.5E-127 T 11-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 AFK25_08635 ec892a353893ca0e990887d20a60543d 373 PIRSF PIRSF006078 1 373 8.1E-121 T 11-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 AFK25_08635 ec892a353893ca0e990887d20a60543d 373 Pfam PF02595 Glycerate kinase family 3 370 9.6E-132 T 11-10-2018 IPR004381 Glycerate kinase GO:0008887|GO:0031388 AFK25_08635 ec892a353893ca0e990887d20a60543d 373 Gene3D G3DSA:3.40.50.10350 1 358 1.3E-128 T 11-10-2018 IPR018197 Glycerate kinase, restriction-enzyme-like fold AFK25_08635 ec892a353893ca0e990887d20a60543d 373 SUPERFAMILY SSF110738 1 369 3.4E-121 T 11-10-2018 IPR036129 Glycerate kinase superfamily GO:0008887|GO:0031388 AFK25_08080 5d4aa6b0a4d12de6cc0e9ddb7e1f1cf5 387 PIRSF PIRSF001413 2 387 1.1E-155 T 11-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFK25_08080 5d4aa6b0a4d12de6cc0e9ddb7e1f1cf5 387 SUPERFAMILY SSF53686 7 382 2.62E-138 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFK25_08080 5d4aa6b0a4d12de6cc0e9ddb7e1f1cf5 387 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 55 372 1.1E-52 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFK25_08080 5d4aa6b0a4d12de6cc0e9ddb7e1f1cf5 387 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 4 385 48.262 T 11-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFK25_08080 5d4aa6b0a4d12de6cc0e9ddb7e1f1cf5 387 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 9 383 1.8E-174 T 11-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFK25_08080 5d4aa6b0a4d12de6cc0e9ddb7e1f1cf5 387 Gene3D G3DSA:3.40.50.1100 12 208 3.3E-173 T 11-10-2018 AFK25_08080 5d4aa6b0a4d12de6cc0e9ddb7e1f1cf5 387 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 83 97 - T 11-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFK25_08080 5d4aa6b0a4d12de6cc0e9ddb7e1f1cf5 387 Gene3D G3DSA:3.40.50.1100 56 378 3.3E-173 T 11-10-2018 AFK25_10895 0d5f1899bd7565d85766480e793207da 177 Gene3D G3DSA:1.10.10.10 1 67 1.8E-17 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_10895 0d5f1899bd7565d85766480e793207da 177 Gene3D G3DSA:3.30.1340.20 72 177 9.8E-37 T 11-10-2018 IPR035922 3H domain superfamily AFK25_10895 0d5f1899bd7565d85766480e793207da 177 ProDom PD469575 TRANSCRIPTION DNA-BINDING REGULATION TRANSCRIPTIONAL REGULATOR REPRESSOR FAMILY BIOTIN REGULATOR 3H 83 176 5.0E-38 T 11-10-2018 IPR004173 3H domain GO:0036094 AFK25_10895 0d5f1899bd7565d85766480e793207da 177 SUPERFAMILY SSF46785 9 67 8.17E-11 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_10895 0d5f1899bd7565d85766480e793207da 177 Pfam PF02829 3H domain 79 175 6.3E-35 T 11-10-2018 IPR004173 3H domain GO:0036094 AFK25_10895 0d5f1899bd7565d85766480e793207da 177 PIRSF PIRSF037847 7 177 1.5E-67 T 11-10-2018 IPR026043 Transcription repressor NadR AFK25_10895 0d5f1899bd7565d85766480e793207da 177 Pfam PF08279 HTH domain 12 64 2.0E-15 T 11-10-2018 IPR013196 Helix-turn-helix, type 11 AFK25_10895 0d5f1899bd7565d85766480e793207da 177 SUPERFAMILY SSF75500 73 177 8.37E-35 T 11-10-2018 IPR035922 3H domain superfamily AFK25_08380 e6a8cef3d879e243425c9033ac5256ee 630 Pfam PF13537 Glutamine amidotransferase domain 51 168 6.6E-46 T 11-10-2018 IPR017932 Glutamine amidotransferase type 2 domain AFK25_08380 e6a8cef3d879e243425c9033ac5256ee 630 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 547 8.6E-174 T 11-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 AFK25_08380 e6a8cef3d879e243425c9033ac5256ee 630 Gene3D G3DSA:3.60.20.10 5 190 5.6E-64 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFK25_08380 e6a8cef3d879e243425c9033ac5256ee 630 Pfam PF00733 Asparagine synthase 240 610 9.2E-114 T 11-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 AFK25_08380 e6a8cef3d879e243425c9033ac5256ee 630 SUPERFAMILY SSF52402 227 605 7.45E-91 T 11-10-2018 AFK25_08380 e6a8cef3d879e243425c9033ac5256ee 630 SUPERFAMILY SSF56235 1 224 2.32E-60 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFK25_08380 e6a8cef3d879e243425c9033ac5256ee 630 PIRSF PIRSF001589 1 627 8.8E-204 T 11-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 AFK25_04710 d6c3270634f94a1e272333794d65957c 301 SUPERFAMILY SSF50341 7 152 1.09E-36 T 11-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 AFK25_04710 d6c3270634f94a1e272333794d65957c 301 Gene3D G3DSA:2.40.50.180 34 149 7.7E-37 T 11-10-2018 AFK25_04710 d6c3270634f94a1e272333794d65957c 301 PIRSF PIRSF002867 1 301 1.5E-106 T 11-10-2018 IPR024181 Chemotaxis response regulator CheV AFK25_04710 d6c3270634f94a1e272333794d65957c 301 Pfam PF00072 Response regulator receiver domain 177 296 1.8E-23 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_04710 d6c3270634f94a1e272333794d65957c 301 Gene3D G3DSA:2.30.30.40 19 143 7.7E-37 T 11-10-2018 AFK25_04710 d6c3270634f94a1e272333794d65957c 301 SUPERFAMILY SSF52172 172 300 1.85E-26 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_04710 d6c3270634f94a1e272333794d65957c 301 Pfam PF01584 CheW-like domain 18 150 1.0E-36 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFK25_04710 d6c3270634f94a1e272333794d65957c 301 SMART SM00260 13 149 4.3E-36 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFK25_04710 d6c3270634f94a1e272333794d65957c 301 SMART SM00448 174 296 9.7E-26 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_04710 d6c3270634f94a1e272333794d65957c 301 Gene3D G3DSA:3.40.50.2300 168 301 3.3E-28 T 11-10-2018 AFK25_14165 7e9888b7b9bb5134e3170f313ad30481 224 Pfam PF03167 Uracil DNA glycosylase superfamily 51 208 2.8E-27 T 11-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFK25_14165 7e9888b7b9bb5134e3170f313ad30481 224 SMART SM00987 49 209 3.2E-37 T 11-10-2018 AFK25_14165 7e9888b7b9bb5134e3170f313ad30481 224 ProSitePatterns PS00130 Uracil-DNA glycosylase signature. 57 66 - T 11-10-2018 IPR018085 Uracil-DNA glycosylase, active site GO:0006281|GO:0016799 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFK25_14165 7e9888b7b9bb5134e3170f313ad30481 224 SUPERFAMILY SSF52141 2 221 5.98E-98 T 11-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFK25_14165 7e9888b7b9bb5134e3170f313ad30481 224 Gene3D G3DSA:3.40.470.10 1 224 5.2E-102 T 11-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFK25_14165 7e9888b7b9bb5134e3170f313ad30481 224 TIGRFAM TIGR00628 ung: uracil-DNA glycosylase 6 213 6.7E-85 T 11-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFK25_14165 7e9888b7b9bb5134e3170f313ad30481 224 Hamap MF_00148 Uracil-DNA glycosylase [ung]. 5 220 41.943 T 11-10-2018 IPR002043 Uracil-DNA glycosylase family 1 GO:0004844|GO:0006281|GO:0006284 Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFK25_14165 7e9888b7b9bb5134e3170f313ad30481 224 SMART SM00986 49 209 3.2E-37 T 11-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AFK25_04855 6dc9264de658c81f8a86b81bd4d4855b 184 SUPERFAMILY SSF56420 2 173 3.01E-60 T 11-10-2018 IPR036821 Peptide deformylase superfamily AFK25_04855 6dc9264de658c81f8a86b81bd4d4855b 184 PIRSF PIRSF004749 1 183 2.4E-49 T 11-10-2018 IPR023635 Peptide deformylase AFK25_04855 6dc9264de658c81f8a86b81bd4d4855b 184 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 174 9.6E-48 T 11-10-2018 IPR023635 Peptide deformylase AFK25_04855 6dc9264de658c81f8a86b81bd4d4855b 184 Gene3D G3DSA:3.90.45.10 1 184 2.6E-68 T 11-10-2018 IPR036821 Peptide deformylase superfamily AFK25_04855 6dc9264de658c81f8a86b81bd4d4855b 184 Pfam PF01327 Polypeptide deformylase 4 171 8.4E-46 T 11-10-2018 IPR023635 Peptide deformylase AFK25_04855 6dc9264de658c81f8a86b81bd4d4855b 184 Hamap MF_00163 Peptide deformylase [def]. 3 182 27.317 T 11-10-2018 IPR023635 Peptide deformylase AFK25_04855 6dc9264de658c81f8a86b81bd4d4855b 184 PRINTS PR01576 Peptide deformylase signature 121 139 1.0E-30 T 11-10-2018 IPR023635 Peptide deformylase AFK25_04855 6dc9264de658c81f8a86b81bd4d4855b 184 PRINTS PR01576 Peptide deformylase signature 108 119 1.0E-30 T 11-10-2018 IPR023635 Peptide deformylase AFK25_04855 6dc9264de658c81f8a86b81bd4d4855b 184 PRINTS PR01576 Peptide deformylase signature 47 76 1.0E-30 T 11-10-2018 IPR023635 Peptide deformylase AFK25_04855 6dc9264de658c81f8a86b81bd4d4855b 184 PRINTS PR01576 Peptide deformylase signature 140 169 1.0E-30 T 11-10-2018 IPR023635 Peptide deformylase AFK25_04995 4b6c0e668781b37263b544b6d7c29358 402 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 338 362 - T 11-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_04995 4b6c0e668781b37263b544b6d7c29358 402 Pfam PF01098 Cell cycle protein 18 380 1.1E-109 T 11-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_04995 4b6c0e668781b37263b544b6d7c29358 402 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 15 377 6.6E-103 T 11-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_03310 e61e20e9b0484552256c9416af000dd4 1129 SMART SM01018 622 704 2.3E-38 T 11-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_03310 e61e20e9b0484552256c9416af000dd4 1129 Gene3D G3DSA:3.20.20.330 1 318 1.9E-111 T 11-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 AFK25_03310 e61e20e9b0484552256c9416af000dd4 1129 Gene3D G3DSA:3.40.50.280 706 855 3.3E-46 T 11-10-2018 AFK25_03310 e61e20e9b0484552256c9416af000dd4 1129 SUPERFAMILY SSF56507 864 1128 3.53E-87 T 11-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_03310 e61e20e9b0484552256c9416af000dd4 1129 Gene3D G3DSA:1.10.288.10 882 940 1.8E-64 T 11-10-2018 AFK25_03310 e61e20e9b0484552256c9416af000dd4 1129 SUPERFAMILY SSF47644 621 703 2.88E-23 T 11-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_03310 e61e20e9b0484552256c9416af000dd4 1129 Gene3D G3DSA:3.20.20.20 319 614 1.4E-104 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_03310 e61e20e9b0484552256c9416af000dd4 1129 TIGRFAM TIGR02082 metH: methionine synthase 8 1128 0.0 T 11-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_03310 e61e20e9b0484552256c9416af000dd4 1129 PIRSF PIRSF000381 1 1129 0.0 T 11-10-2018 IPR011822 Cobalamin-dependent methionine synthase GO:0008270|GO:0008705|GO:0009086|GO:0031419 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_03310 e61e20e9b0484552256c9416af000dd4 1129 Pfam PF02965 Vitamin B12 dependent methionine synthase, activation domain 884 1128 4.8E-58 T 11-10-2018 IPR004223 Vitamin B12-dependent methionine synthase, activation domain GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_03310 e61e20e9b0484552256c9416af000dd4 1129 Pfam PF02574 Homocysteine S-methyltransferase 13 303 5.7E-77 T 11-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 AFK25_03310 e61e20e9b0484552256c9416af000dd4 1129 Pfam PF02310 B12 binding domain 710 826 5.2E-21 T 11-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFK25_03310 e61e20e9b0484552256c9416af000dd4 1129 Pfam PF00809 Pterin binding enzyme 338 571 1.2E-41 T 11-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_03310 e61e20e9b0484552256c9416af000dd4 1129 Pfam PF02607 B12 binding domain 625 697 2.0E-21 T 11-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_03310 e61e20e9b0484552256c9416af000dd4 1129 SUPERFAMILY SSF82282 3 377 4.84E-115 T 11-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 AFK25_03310 e61e20e9b0484552256c9416af000dd4 1129 SUPERFAMILY SSF51717 335 598 1.31E-80 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_03310 e61e20e9b0484552256c9416af000dd4 1129 Gene3D G3DSA:3.10.196.10 861 1128 1.8E-64 T 11-10-2018 IPR037010 Vitamin B12-dependent methionine synthase, activation domain superfamily GO:0008705|GO:0009086 KEGG: 00270+2.1.1.13|KEGG: 00450+2.1.1.13|KEGG: 00670+2.1.1.13|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-7977|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_03310 e61e20e9b0484552256c9416af000dd4 1129 Gene3D G3DSA:1.10.1240.10 615 701 2.3E-26 T 11-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_03310 e61e20e9b0484552256c9416af000dd4 1129 SUPERFAMILY SSF52242 705 834 7.98E-39 T 11-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFK25_05875 aa8b17cef2f61d355ce7449904da482a 367 SMART SM00316 133 199 4.2E-12 T 11-10-2018 IPR022967 RNA-binding domain, S1 AFK25_05875 aa8b17cef2f61d355ce7449904da482a 367 Pfam PF08529 NusA N-terminal domain 4 123 9.9E-47 T 11-10-2018 IPR013735 Transcription factor NusA, N-terminal GO:0003700|GO:0031554 AFK25_05875 aa8b17cef2f61d355ce7449904da482a 367 Gene3D G3DSA:3.30.300.20 278 367 1.2E-32 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta AFK25_05875 aa8b17cef2f61d355ce7449904da482a 367 SMART SM00322 302 367 11.0 T 11-10-2018 IPR004087 K Homology domain GO:0003676 AFK25_05875 aa8b17cef2f61d355ce7449904da482a 367 SMART SM00322 229 301 1.8E-4 T 11-10-2018 IPR004087 K Homology domain GO:0003676 AFK25_05875 aa8b17cef2f61d355ce7449904da482a 367 SUPERFAMILY SSF50249 132 198 2.39E-20 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_05875 aa8b17cef2f61d355ce7449904da482a 367 Pfam PF00575 S1 RNA binding domain 133 195 8.4E-14 T 11-10-2018 IPR003029 S1 domain GO:0003676 AFK25_05875 aa8b17cef2f61d355ce7449904da482a 367 Gene3D G3DSA:2.40.50.140 136 197 2.2E-25 T 11-10-2018 AFK25_05875 aa8b17cef2f61d355ce7449904da482a 367 SUPERFAMILY SSF69705 1 126 1.31E-46 T 11-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 AFK25_05875 aa8b17cef2f61d355ce7449904da482a 367 TIGRFAM TIGR01953 NusA: transcription termination factor NusA 4 341 2.4E-134 T 11-10-2018 IPR010213 Transcription termination factor NusA GO:0003723 AFK25_05875 aa8b17cef2f61d355ce7449904da482a 367 SUPERFAMILY SSF54814 199 276 2.68E-31 T 11-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AFK25_05875 aa8b17cef2f61d355ce7449904da482a 367 SUPERFAMILY SSF54814 278 342 2.42E-16 T 11-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AFK25_05875 aa8b17cef2f61d355ce7449904da482a 367 Hamap MF_00945_B Transcription termination/antitermination protein NusA [nusA]. 2 367 30.71 T 11-10-2018 IPR030842 Transcription termination/antitermination protein NusA, bacterial GO:0006353|GO:0031564 AFK25_05875 aa8b17cef2f61d355ce7449904da482a 367 Gene3D G3DSA:3.30.1480.10 1 124 1.2E-52 T 11-10-2018 IPR036555 NusA, N-terminal domain superfamily GO:0003700|GO:0031554 AFK25_05875 aa8b17cef2f61d355ce7449904da482a 367 Gene3D G3DSA:3.30.300.20 198 276 3.1E-35 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta AFK25_05875 aa8b17cef2f61d355ce7449904da482a 367 Pfam PF13184 NusA-like KH domain 229 296 4.8E-29 T 11-10-2018 IPR025249 KH domain, NusA-like GO:0003723 AFK25_04195 c918c8421a6ccf0a69b9bdf70bb33e67 567 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 463 565 6.9E-20 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_04195 c918c8421a6ccf0a69b9bdf70bb33e67 567 Gene3D G3DSA:1.10.287.130 340 416 2.0E-17 T 11-10-2018 AFK25_04195 c918c8421a6ccf0a69b9bdf70bb33e67 567 SUPERFAMILY SSF55874 412 565 5.37E-38 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_04195 c918c8421a6ccf0a69b9bdf70bb33e67 567 PRINTS PR00344 Bacterial sensor protein C-terminal signature 527 545 6.7E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04195 c918c8421a6ccf0a69b9bdf70bb33e67 567 PRINTS PR00344 Bacterial sensor protein C-terminal signature 551 564 6.7E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04195 c918c8421a6ccf0a69b9bdf70bb33e67 567 PRINTS PR00344 Bacterial sensor protein C-terminal signature 498 512 6.7E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04195 c918c8421a6ccf0a69b9bdf70bb33e67 567 PRINTS PR00344 Bacterial sensor protein C-terminal signature 516 526 6.7E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04195 c918c8421a6ccf0a69b9bdf70bb33e67 567 SMART SM00388 356 422 6.3E-14 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_04195 c918c8421a6ccf0a69b9bdf70bb33e67 567 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 235 347 1.5E-5 T 11-10-2018 IPR000014 PAS domain AFK25_04195 c918c8421a6ccf0a69b9bdf70bb33e67 567 SUPERFAMILY SSF47384 350 420 2.35E-12 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFK25_04195 c918c8421a6ccf0a69b9bdf70bb33e67 567 Gene3D G3DSA:3.30.450.20 221 339 3.0E-9 T 11-10-2018 AFK25_04195 c918c8421a6ccf0a69b9bdf70bb33e67 567 SUPERFAMILY SSF55785 239 340 2.47E-6 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_04195 c918c8421a6ccf0a69b9bdf70bb33e67 567 SMART SM00387 462 567 1.4E-31 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_04195 c918c8421a6ccf0a69b9bdf70bb33e67 567 Gene3D G3DSA:3.30.565.10 417 565 7.0E-41 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_04195 c918c8421a6ccf0a69b9bdf70bb33e67 567 Pfam PF00512 His Kinase A (phospho-acceptor) domain 357 419 1.2E-12 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_02730 93360210e4a91688bdaba2f24428b801 421 Gene3D G3DSA:3.10.580.10 182 329 1.8E-53 T 11-10-2018 AFK25_02730 93360210e4a91688bdaba2f24428b801 421 SUPERFAMILY SSF56176 336 417 5.73E-19 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFK25_02730 93360210e4a91688bdaba2f24428b801 421 Pfam PF01595 Domain of unknown function DUF21 11 188 1.6E-50 T 11-10-2018 IPR002550 CNNM, transmembrane domain AFK25_02730 93360210e4a91688bdaba2f24428b801 421 SMART SM01091 337 415 4.5E-25 T 11-10-2018 IPR005170 Transporter-associated domain AFK25_02730 93360210e4a91688bdaba2f24428b801 421 Pfam PF03471 Transporter associated domain 338 414 2.1E-19 T 11-10-2018 IPR005170 Transporter-associated domain AFK25_02730 93360210e4a91688bdaba2f24428b801 421 SMART SM00116 212 261 0.0061 T 11-10-2018 IPR000644 CBS domain AFK25_02730 93360210e4a91688bdaba2f24428b801 421 SMART SM00116 275 322 54.0 T 11-10-2018 IPR000644 CBS domain AFK25_02730 93360210e4a91688bdaba2f24428b801 421 SUPERFAMILY SSF54631 198 340 3.66E-33 T 11-10-2018 AFK25_02730 93360210e4a91688bdaba2f24428b801 421 Gene3D G3DSA:3.30.465.10 330 412 1.0E-21 T 11-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFK25_02730 93360210e4a91688bdaba2f24428b801 421 Pfam PF00571 CBS domain 203 260 6.2E-8 T 11-10-2018 IPR000644 CBS domain AFK25_02730 93360210e4a91688bdaba2f24428b801 421 Pfam PF00571 CBS domain 268 322 0.0021 T 11-10-2018 IPR000644 CBS domain AFK25_01575 910c604ccf7807324846ec5e49215aa4 251 SMART SM00382 33 247 2.7E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_01575 910c604ccf7807324846ec5e49215aa4 251 SUPERFAMILY SSF52540 4 228 1.08E-76 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_01575 910c604ccf7807324846ec5e49215aa4 251 Gene3D G3DSA:3.40.50.300 1 249 1.3E-72 T 11-10-2018 AFK25_01575 910c604ccf7807324846ec5e49215aa4 251 Pfam PF00005 ABC transporter 24 172 1.5E-35 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_01575 910c604ccf7807324846ec5e49215aa4 251 ProSitePatterns PS00211 ABC transporters family signature. 145 159 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_01820 19aab688e8bd0185f1a83afed5b6c308 452 Gene3D G3DSA:3.40.50.150 80 446 2.1E-112 T 11-10-2018 AFK25_01820 19aab688e8bd0185f1a83afed5b6c308 452 Gene3D G3DSA:3.40.1350.30 129 284 2.1E-112 T 11-10-2018 AFK25_01820 19aab688e8bd0185f1a83afed5b6c308 452 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 88 450 7.7E-18 T 11-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 AFK25_01820 19aab688e8bd0185f1a83afed5b6c308 452 Pfam PF01938 TRAM domain 3 58 3.4E-12 T 11-10-2018 IPR002792 TRAM domain AFK25_01820 19aab688e8bd0185f1a83afed5b6c308 452 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 15 444 1.0E-176 T 11-10-2018 AFK25_01820 19aab688e8bd0185f1a83afed5b6c308 452 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 434 444 - T 11-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site AFK25_01820 19aab688e8bd0185f1a83afed5b6c308 452 SUPERFAMILY SSF50249 2 58 6.28E-15 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_01820 19aab688e8bd0185f1a83afed5b6c308 452 SUPERFAMILY SSF53335 67 451 3.06E-85 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_01820 19aab688e8bd0185f1a83afed5b6c308 452 Gene3D G3DSA:2.40.50.140 2 78 6.3E-23 T 11-10-2018 AFK25_01820 19aab688e8bd0185f1a83afed5b6c308 452 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 383 414 - T 11-10-2018 IPR030390 RNA methyltransferase TrmA, active site AFK25_00665 d4249853a48be2d746988e890506bb05 179 Gene3D G3DSA:3.30.1440.10 1 179 1.8E-85 T 11-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00665 d4249853a48be2d746988e890506bb05 179 PIRSF PIRSF002161 1 179 5.8E-70 T 11-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00665 d4249853a48be2d746988e890506bb05 179 Pfam PF00673 ribosomal L5P family C-terminus 84 177 5.3E-42 T 11-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00665 d4249853a48be2d746988e890506bb05 179 Hamap MF_01333_B 50S ribosomal protein L5 [rplE]. 1 179 46.339 T 11-10-2018 IPR020930 Ribosomal protein L5, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00665 d4249853a48be2d746988e890506bb05 179 ProSitePatterns PS00358 Ribosomal protein L5 signature. 57 73 - T 11-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00665 d4249853a48be2d746988e890506bb05 179 SUPERFAMILY SSF55282 3 178 5.65E-80 T 11-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00665 d4249853a48be2d746988e890506bb05 179 Pfam PF00281 Ribosomal protein L5 24 80 1.7E-29 T 11-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00520 11029e811be45d19fe83abc8a2eba69a 216 Pfam PF08281 Sigma-70, region 4 159 205 8.4E-11 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFK25_00520 11029e811be45d19fe83abc8a2eba69a 216 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 31 208 4.0E-27 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFK25_00520 11029e811be45d19fe83abc8a2eba69a 216 PIRSF PIRSF002939 1 216 5.8E-109 T 11-10-2018 IPR016371 RNA polymerase sigma-H factor GO:0003677|GO:0006351|GO:0016987 AFK25_00520 11029e811be45d19fe83abc8a2eba69a 216 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 60 73 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_00520 11029e811be45d19fe83abc8a2eba69a 216 SUPERFAMILY SSF88659 123 209 1.44E-11 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFK25_00520 11029e811be45d19fe83abc8a2eba69a 216 SUPERFAMILY SSF88946 17 102 1.7E-23 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_00520 11029e811be45d19fe83abc8a2eba69a 216 TIGRFAM TIGR02859 spore_sigH: RNA polymerase sigma-H factor 13 210 7.3E-110 T 11-10-2018 IPR014218 RNA polymerase sigma-H type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFK25_00520 11029e811be45d19fe83abc8a2eba69a 216 Pfam PF04542 Sigma-70 region 2 36 104 6.3E-14 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_00520 11029e811be45d19fe83abc8a2eba69a 216 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_01325 b1926d775d48500c6b32c1531dc6fa8a 345 SUPERFAMILY SSF56042 169 337 2.09E-61 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFK25_01325 b1926d775d48500c6b32c1531dc6fa8a 345 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 4 333 4.1E-141 T 11-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFK25_01325 b1926d775d48500c6b32c1531dc6fa8a 345 Pfam PF02769 AIR synthase related protein, C-terminal domain 174 338 3.3E-36 T 11-10-2018 IPR010918 PurM-like, C-terminal domain AFK25_01325 b1926d775d48500c6b32c1531dc6fa8a 345 Pfam PF00586 AIR synthase related protein, N-terminal domain 58 161 2.8E-17 T 11-10-2018 IPR016188 PurM-like, N-terminal domain AFK25_01325 b1926d775d48500c6b32c1531dc6fa8a 345 Gene3D G3DSA:3.90.650.10 168 344 5.9E-71 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFK25_01325 b1926d775d48500c6b32c1531dc6fa8a 345 SUPERFAMILY SSF55326 3 166 1.21E-49 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFK25_01325 b1926d775d48500c6b32c1531dc6fa8a 345 Gene3D G3DSA:3.30.1330.10 1 167 2.4E-68 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFK25_01325 b1926d775d48500c6b32c1531dc6fa8a 345 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 3 340 47.707 T 11-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFK25_13345 3df4b77eca77e3e8ec78f33cdda8239e 640 Pfam PF00395 S-layer homology domain 56 96 1.9E-10 T 11-10-2018 IPR001119 S-layer homology domain AFK25_13345 3df4b77eca77e3e8ec78f33cdda8239e 640 Pfam PF00395 S-layer homology domain 118 153 1.1E-5 T 11-10-2018 IPR001119 S-layer homology domain AFK25_13345 3df4b77eca77e3e8ec78f33cdda8239e 640 Pfam PF00149 Calcineurin-like phosphoesterase 175 376 1.3E-16 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFK25_13345 3df4b77eca77e3e8ec78f33cdda8239e 640 SUPERFAMILY SSF56300 170 447 1.57E-77 T 11-10-2018 AFK25_13345 3df4b77eca77e3e8ec78f33cdda8239e 640 PRINTS PR01607 Apyrase family signature 503 526 6.3E-37 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFK25_13345 3df4b77eca77e3e8ec78f33cdda8239e 640 PRINTS PR01607 Apyrase family signature 576 595 6.3E-37 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFK25_13345 3df4b77eca77e3e8ec78f33cdda8239e 640 PRINTS PR01607 Apyrase family signature 359 382 6.3E-37 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFK25_13345 3df4b77eca77e3e8ec78f33cdda8239e 640 PRINTS PR01607 Apyrase family signature 340 357 6.3E-37 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFK25_13345 3df4b77eca77e3e8ec78f33cdda8239e 640 PRINTS PR01607 Apyrase family signature 387 407 6.3E-37 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFK25_13345 3df4b77eca77e3e8ec78f33cdda8239e 640 PRINTS PR01607 Apyrase family signature 172 190 6.3E-37 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFK25_13345 3df4b77eca77e3e8ec78f33cdda8239e 640 Pfam PF02872 5'-nucleotidase, C-terminal domain 449 602 4.8E-56 T 11-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFK25_13345 3df4b77eca77e3e8ec78f33cdda8239e 640 Gene3D G3DSA:3.90.780.10 450 640 6.9E-75 T 11-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFK25_13345 3df4b77eca77e3e8ec78f33cdda8239e 640 SUPERFAMILY SSF55816 446 639 7.46E-71 T 11-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFK25_13345 3df4b77eca77e3e8ec78f33cdda8239e 640 Gene3D G3DSA:3.60.21.10 168 449 3.0E-84 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like AFK25_07440 d9d851a673483435d74a4eb8023a09fd 140 Hamap MF_01624 Arsenate reductase [arsC]. 2 138 47.062 T 11-10-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 AFK25_07440 d9d851a673483435d74a4eb8023a09fd 140 SUPERFAMILY SSF52788 7 137 4.97E-47 T 11-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily AFK25_07440 d9d851a673483435d74a4eb8023a09fd 140 Gene3D G3DSA:3.40.50.2300 3 140 9.4E-61 T 11-10-2018 AFK25_07440 d9d851a673483435d74a4eb8023a09fd 140 SMART SM00226 5 138 6.5E-63 T 11-10-2018 IPR023485 Phosphotyrosine protein phosphatase I AFK25_07440 d9d851a673483435d74a4eb8023a09fd 140 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 7 135 5.9E-24 T 11-10-2018 IPR023485 Phosphotyrosine protein phosphatase I AFK25_07440 d9d851a673483435d74a4eb8023a09fd 140 TIGRFAM TIGR02691 arsC_pI258_fam: arsenate reductase (thioredoxin) 7 135 8.7E-74 T 11-10-2018 IPR014064 Arsenate reductase ArsC GO:0004725|GO:0030612|GO:0046685 AFK25_14005 b0ba04aad8fca1385674ef22af5afd70 379 Gene3D G3DSA:2.40.110.10 121 234 4.3E-51 T 11-10-2018 AFK25_14005 b0ba04aad8fca1385674ef22af5afd70 379 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 376 4.8E-53 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFK25_14005 b0ba04aad8fca1385674ef22af5afd70 379 PIRSF PIRSF016578 3 377 1.5E-22 T 11-10-2018 AFK25_14005 b0ba04aad8fca1385674ef22af5afd70 379 Gene3D G3DSA:1.20.140.10 235 379 2.0E-58 T 11-10-2018 AFK25_14005 b0ba04aad8fca1385674ef22af5afd70 379 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFK25_14005 b0ba04aad8fca1385674ef22af5afd70 379 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 5.4E-41 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFK25_14005 b0ba04aad8fca1385674ef22af5afd70 379 SUPERFAMILY SSF47203 227 378 3.06E-62 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFK25_14005 b0ba04aad8fca1385674ef22af5afd70 379 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 217 3.0E-30 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFK25_14005 b0ba04aad8fca1385674ef22af5afd70 379 Gene3D G3DSA:1.10.540.10 1 120 5.9E-46 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFK25_14005 b0ba04aad8fca1385674ef22af5afd70 379 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 336 355 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFK25_14005 b0ba04aad8fca1385674ef22af5afd70 379 SUPERFAMILY SSF56645 1 242 2.23E-98 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFK25_05310 4ddf451c406695ff5ee5229398752537 167 Pfam PF05103 DivIVA protein 3 133 1.3E-52 T 11-10-2018 IPR007793 DivIVA family AFK25_05310 4ddf451c406695ff5ee5229398752537 167 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 3 36 4.3E-18 T 11-10-2018 IPR019933 DivIVA domain AFK25_00735 723f35ffcdc4da2dfd82aa62887133b9 129 ProSitePatterns PS00054 Ribosomal protein S11 signature. 97 119 - T 11-10-2018 IPR018102 Ribosomal S11, conserved site AFK25_00735 723f35ffcdc4da2dfd82aa62887133b9 129 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 3 129 34.658 T 11-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AFK25_00735 723f35ffcdc4da2dfd82aa62887133b9 129 TIGRFAM TIGR03632 uS11_bact: ribosomal protein uS11 10 126 6.2E-60 T 11-10-2018 IPR019981 Ribosomal protein S11, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00735 723f35ffcdc4da2dfd82aa62887133b9 129 PIRSF PIRSF002131 1 129 6.6E-55 T 11-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AFK25_00735 723f35ffcdc4da2dfd82aa62887133b9 129 SUPERFAMILY SSF53137 14 129 7.85E-51 T 11-10-2018 AFK25_00735 723f35ffcdc4da2dfd82aa62887133b9 129 Pfam PF00411 Ribosomal protein S11 19 128 1.1E-53 T 11-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AFK25_00735 723f35ffcdc4da2dfd82aa62887133b9 129 Gene3D G3DSA:3.30.420.80 1 129 1.2E-55 T 11-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 AFK25_09340 ee0f9e3a18180b9491ccdd392caa4398 397 PIRSF PIRSF001259 1 397 1.5E-193 T 11-10-2018 AFK25_09340 ee0f9e3a18180b9491ccdd392caa4398 397 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 202 397 43.075 T 11-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFK25_09340 ee0f9e3a18180b9491ccdd392caa4398 397 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 196 2.3E-85 T 11-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFK25_09340 ee0f9e3a18180b9491ccdd392caa4398 397 SUPERFAMILY SSF55821 2 204 2.04E-85 T 11-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AFK25_09340 ee0f9e3a18180b9491ccdd392caa4398 397 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 207 395 1.1E-82 T 11-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFK25_09340 ee0f9e3a18180b9491ccdd392caa4398 397 Gene3D G3DSA:3.40.50.10990 204 374 2.0E-79 T 11-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFK25_09340 ee0f9e3a18180b9491ccdd392caa4398 397 Pfam PF00925 GTP cyclohydrolase II 206 371 1.9E-78 T 11-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFK25_09340 ee0f9e3a18180b9491ccdd392caa4398 397 Hamap MF_01283 Riboflavin biosynthesis protein RibBA [ribBA]. 1 393 57.183 T 11-10-2018 IPR016299 Riboflavin biosynthesis protein RibBA GO:0009231 KEGG: 00740+3.5.4.25+4.1.99.12|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFK25_09340 ee0f9e3a18180b9491ccdd392caa4398 397 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 1 197 1.0E-80 T 11-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFK25_09340 ee0f9e3a18180b9491ccdd392caa4398 397 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 201 38.612 T 11-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFK25_09340 ee0f9e3a18180b9491ccdd392caa4398 397 Gene3D G3DSA:3.90.870.10 1 203 2.8E-90 T 11-10-2018 AFK25_09340 ee0f9e3a18180b9491ccdd392caa4398 397 SUPERFAMILY SSF142695 202 374 1.44E-76 T 11-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AFK25_08095 a3c05a94c236da9079d6d9829ad62e23 556 Gene3D G3DSA:2.40.110.20 121 273 1.4E-39 T 11-10-2018 AFK25_08095 a3c05a94c236da9079d6d9829ad62e23 556 Gene3D G3DSA:1.20.140.10 275 436 9.8E-41 T 11-10-2018 AFK25_08095 a3c05a94c236da9079d6d9829ad62e23 556 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 165 264 6.6E-20 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFK25_08095 a3c05a94c236da9079d6d9829ad62e23 556 SUPERFAMILY SSF56645 47 284 7.07E-43 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFK25_08095 a3c05a94c236da9079d6d9829ad62e23 556 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 393 412 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFK25_08095 a3c05a94c236da9079d6d9829ad62e23 556 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 275 430 1.2E-34 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFK25_08095 a3c05a94c236da9079d6d9829ad62e23 556 SUPERFAMILY SSF47203 278 437 1.22E-39 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFK25_14250 658aa749a01756cde7c1183e94774ddb 407 Pfam PF13556 PucR C-terminal helix-turn-helix domain 343 400 1.6E-20 T 11-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain AFK25_14250 658aa749a01756cde7c1183e94774ddb 407 SUPERFAMILY SSF46689 348 378 9.68E-5 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_14250 658aa749a01756cde7c1183e94774ddb 407 Gene3D G3DSA:1.10.10.2840 273 405 2.6E-21 T 11-10-2018 AFK25_14320 44f606b5550b99c0a52ea71fbc8c36e9 432 Pfam PF02687 FtsX-like permease family 334 421 4.1E-6 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFK25_11480 39ca443b4495f375b6fb5c8f3c5fa384 392 Pfam PF08544 GHMP kinases C terminal 282 362 1.8E-12 T 11-10-2018 IPR013750 GHMP kinase, C-terminal domain AFK25_11480 39ca443b4495f375b6fb5c8f3c5fa384 392 SUPERFAMILY SSF54211 2 201 9.11E-64 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFK25_11480 39ca443b4495f375b6fb5c8f3c5fa384 392 PRINTS PR00959 Mevalonate kinase family signature 330 347 7.1E-44 T 11-10-2018 AFK25_11480 39ca443b4495f375b6fb5c8f3c5fa384 392 PRINTS PR00959 Mevalonate kinase family signature 160 179 7.1E-44 T 11-10-2018 AFK25_11480 39ca443b4495f375b6fb5c8f3c5fa384 392 PRINTS PR00959 Mevalonate kinase family signature 24 48 7.1E-44 T 11-10-2018 AFK25_11480 39ca443b4495f375b6fb5c8f3c5fa384 392 PRINTS PR00959 Mevalonate kinase family signature 117 139 7.1E-44 T 11-10-2018 AFK25_11480 39ca443b4495f375b6fb5c8f3c5fa384 392 PRINTS PR00473 Galactokinase signature 91 102 4.9E-28 T 11-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFK25_11480 39ca443b4495f375b6fb5c8f3c5fa384 392 PRINTS PR00473 Galactokinase signature 266 280 4.9E-28 T 11-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFK25_11480 39ca443b4495f375b6fb5c8f3c5fa384 392 PRINTS PR00473 Galactokinase signature 26 44 4.9E-28 T 11-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFK25_11480 39ca443b4495f375b6fb5c8f3c5fa384 392 PRINTS PR00473 Galactokinase signature 110 128 4.9E-28 T 11-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFK25_11480 39ca443b4495f375b6fb5c8f3c5fa384 392 PIRSF PIRSF000530 1 385 2.6E-125 T 11-10-2018 IPR006206 Mevalonate/galactokinase GO:0005524|GO:0005737|GO:0016301|GO:0016773 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFK25_11480 39ca443b4495f375b6fb5c8f3c5fa384 392 Pfam PF00288 GHMP kinases N terminal domain 113 179 6.9E-16 T 11-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 AFK25_11480 39ca443b4495f375b6fb5c8f3c5fa384 392 Hamap MF_00246 Galactokinase [galK]. 24 383 46.023 T 11-10-2018 IPR022963 Galactokinase, bacterial GO:0004335|GO:0006012 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFK25_11480 39ca443b4495f375b6fb5c8f3c5fa384 392 SUPERFAMILY SSF55060 203 382 3.52E-56 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily AFK25_11480 39ca443b4495f375b6fb5c8f3c5fa384 392 ProSitePatterns PS00106 Galactokinase signature. 26 37 - T 11-10-2018 IPR019741 Galactokinase, conserved site KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFK25_11480 39ca443b4495f375b6fb5c8f3c5fa384 392 Gene3D G3DSA:3.30.230.10 21 199 6.6E-138 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFK25_11480 39ca443b4495f375b6fb5c8f3c5fa384 392 Pfam PF10509 Galactokinase galactose-binding signature 7 56 9.9E-21 T 11-10-2018 IPR019539 Galactokinase galactose-binding domain GO:0005534 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFK25_11480 39ca443b4495f375b6fb5c8f3c5fa384 392 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 119 130 - T 11-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 AFK25_11480 39ca443b4495f375b6fb5c8f3c5fa384 392 TIGRFAM TIGR00131 gal_kin: galactokinase 3 383 8.7E-123 T 11-10-2018 IPR000705 Galactokinase GO:0004335|GO:0005524|GO:0006012|GO:0046835 KEGG: 00052+2.7.1.6|KEGG: 00520+2.7.1.6|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFK25_11480 39ca443b4495f375b6fb5c8f3c5fa384 392 Gene3D G3DSA:3.30.70.890 200 359 6.6E-138 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily AFK25_10120 110fa115cf5c1c2d714f71fb9fb16ee0 49 Pfam PF00471 Ribosomal protein L33 3 49 1.9E-23 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10120 110fa115cf5c1c2d714f71fb9fb16ee0 49 Gene3D G3DSA:2.20.28.120 1 49 2.8E-25 T 11-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10120 110fa115cf5c1c2d714f71fb9fb16ee0 49 SUPERFAMILY SSF57829 1 49 1.14E-19 T 11-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AFK25_10120 110fa115cf5c1c2d714f71fb9fb16ee0 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 11-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_10120 110fa115cf5c1c2d714f71fb9fb16ee0 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 5.3E-21 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10120 110fa115cf5c1c2d714f71fb9fb16ee0 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 19.81 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_02950 25a2a33507f9bcc7e6a8e54eb3e41834 220 SUPERFAMILY SSF53098 27 197 7.93E-45 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_02950 25a2a33507f9bcc7e6a8e54eb3e41834 220 SMART SM00479 26 198 1.8E-34 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFK25_02950 25a2a33507f9bcc7e6a8e54eb3e41834 220 Pfam PF00929 Exonuclease 29 189 1.5E-31 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFK25_02950 25a2a33507f9bcc7e6a8e54eb3e41834 220 Gene3D G3DSA:3.30.420.10 18 201 5.1E-44 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFK25_02950 25a2a33507f9bcc7e6a8e54eb3e41834 220 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 27 195 6.8E-26 T 11-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_01475 b77e899be43f4bbead0d2ab7446f5789 456 SMART SM00387 339 455 6.1E-44 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_01475 b77e899be43f4bbead0d2ab7446f5789 456 Gene3D G3DSA:3.30.565.10 295 455 1.5E-51 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_01475 b77e899be43f4bbead0d2ab7446f5789 456 SUPERFAMILY SSF55874 283 452 3.01E-50 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_01475 b77e899be43f4bbead0d2ab7446f5789 456 SUPERFAMILY SSF47384 215 293 3.34E-18 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFK25_01475 b77e899be43f4bbead0d2ab7446f5789 456 SMART SM00388 226 294 1.9E-16 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_01475 b77e899be43f4bbead0d2ab7446f5789 456 Gene3D G3DSA:1.10.287.130 221 294 1.6E-18 T 11-10-2018 AFK25_01475 b77e899be43f4bbead0d2ab7446f5789 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 408 3.1E-20 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_01475 b77e899be43f4bbead0d2ab7446f5789 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 380 394 3.1E-20 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_01475 b77e899be43f4bbead0d2ab7446f5789 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 415 433 3.1E-20 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_01475 b77e899be43f4bbead0d2ab7446f5789 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 439 452 3.1E-20 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_01475 b77e899be43f4bbead0d2ab7446f5789 456 Pfam PF00512 His Kinase A (phospho-acceptor) domain 227 292 8.0E-16 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_01475 b77e899be43f4bbead0d2ab7446f5789 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 339 454 3.2E-29 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_09910 efa4c0bb51cc4a2bdd73f98b666afc78 185 Pfam PF08207 Elongation factor P (EF-P) KOW-like domain 3 60 2.9E-29 T 11-10-2018 IPR013185 Translation elongation factor, KOW-like AFK25_09910 efa4c0bb51cc4a2bdd73f98b666afc78 185 SMART SM00841 129 184 1.1E-35 T 11-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 AFK25_09910 efa4c0bb51cc4a2bdd73f98b666afc78 185 Pfam PF09285 Elongation factor P, C-terminal 129 184 3.9E-27 T 11-10-2018 IPR015365 Elongation factor P, C-terminal GO:0005737|GO:0043043 AFK25_09910 efa4c0bb51cc4a2bdd73f98b666afc78 185 SUPERFAMILY SSF50104 1 63 9.63E-23 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily AFK25_09910 efa4c0bb51cc4a2bdd73f98b666afc78 185 PIRSF PIRSF005901 1 185 3.4E-74 T 11-10-2018 IPR020599 Translation elongation factor P/YeiP AFK25_09910 efa4c0bb51cc4a2bdd73f98b666afc78 185 TIGRFAM TIGR00038 efp: translation elongation factor P 2 185 8.9E-84 T 11-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 AFK25_09910 efa4c0bb51cc4a2bdd73f98b666afc78 185 Gene3D G3DSA:2.40.50.140 64 127 3.6E-27 T 11-10-2018 AFK25_09910 efa4c0bb51cc4a2bdd73f98b666afc78 185 Pfam PF01132 Elongation factor P (EF-P) OB domain 68 121 1.5E-23 T 11-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 AFK25_09910 efa4c0bb51cc4a2bdd73f98b666afc78 185 Gene3D G3DSA:2.30.30.30 1 62 1.6E-32 T 11-10-2018 IPR014722 Ribosomal protein L2, domain 2 AFK25_09910 efa4c0bb51cc4a2bdd73f98b666afc78 185 Gene3D G3DSA:2.40.50.140 128 185 9.0E-28 T 11-10-2018 AFK25_09910 efa4c0bb51cc4a2bdd73f98b666afc78 185 SUPERFAMILY SSF50249 65 129 1.63E-22 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_09910 efa4c0bb51cc4a2bdd73f98b666afc78 185 SUPERFAMILY SSF50249 128 185 2.23E-19 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_09910 efa4c0bb51cc4a2bdd73f98b666afc78 185 SMART SM01185 67 121 8.8E-28 T 11-10-2018 IPR001059 Translation elongation factor P/YeiP, central GO:0003746|GO:0006414 AFK25_09910 efa4c0bb51cc4a2bdd73f98b666afc78 185 ProSitePatterns PS01275 Elongation factor P signature. 150 169 - T 11-10-2018 IPR013852 Translation elongation factor P/YeiP, conserved site AFK25_09910 efa4c0bb51cc4a2bdd73f98b666afc78 185 Hamap MF_00141 Elongation factor P [efp]. 1 185 52.11 T 11-10-2018 IPR011768 Translation elongation factor P GO:0003746|GO:0005737|GO:0006414 AFK25_05925 3acd2c3e39aa9302a11ac5e6932e1663 308 Gene3D G3DSA:3.20.20.370 102 305 8.3E-61 T 11-10-2018 AFK25_05925 3acd2c3e39aa9302a11ac5e6932e1663 308 TIGRFAM TIGR02873 spore_ylxY: probable sporulation protein, polysaccharide deacetylase family 28 295 1.5E-132 T 11-10-2018 IPR014228 Sporulation protein, polysaccharide deacetylase, YlxY AFK25_05925 3acd2c3e39aa9302a11ac5e6932e1663 308 Pfam PF01522 Polysaccharide deacetylase 121 228 1.0E-33 T 11-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFK25_05925 3acd2c3e39aa9302a11ac5e6932e1663 308 SUPERFAMILY SSF88713 79 294 5.78E-62 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFK25_05290 04df6be9440df95f690533912595acbe 227 TIGRFAM TIGR00044 TIGR00044: pyridoxal phosphate enzyme, YggS family 2 223 6.2E-49 T 11-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 AFK25_05290 04df6be9440df95f690533912595acbe 227 SUPERFAMILY SSF51419 1 222 3.34E-72 T 11-10-2018 IPR029066 PLP-binding barrel AFK25_05290 04df6be9440df95f690533912595acbe 227 Hamap MF_02087 Pyridoxal phosphate homeostasis protein. 5 223 27.397 T 11-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 AFK25_05290 04df6be9440df95f690533912595acbe 227 Gene3D G3DSA:3.20.20.10 1 227 2.5E-77 T 11-10-2018 IPR029066 PLP-binding barrel AFK25_05290 04df6be9440df95f690533912595acbe 227 PIRSF PIRSF004848 1 227 5.3E-65 T 11-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 AFK25_05290 04df6be9440df95f690533912595acbe 227 ProSitePatterns PS01211 Uncharacterized protein family UPF0001 signature. 74 88 - T 11-10-2018 IPR011078 Pyridoxal phosphate homeostasis protein GO:0030170 AFK25_05290 04df6be9440df95f690533912595acbe 227 Pfam PF01168 Alanine racemase, N-terminal domain 7 223 7.6E-21 T 11-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFK25_08370 2a4208afdec7cee674097d144413a359 501 SUPERFAMILY SSF51905 17 497 1.68E-41 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_08370 2a4208afdec7cee674097d144413a359 501 Gene3D G3DSA:3.50.50.60 17 104 5.1E-16 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_08370 2a4208afdec7cee674097d144413a359 501 Gene3D G3DSA:3.50.50.60 239 477 6.3E-9 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_08370 2a4208afdec7cee674097d144413a359 501 Gene3D G3DSA:3.90.660.50 234 440 6.3E-9 T 11-10-2018 AFK25_08370 2a4208afdec7cee674097d144413a359 501 Pfam PF13450 NAD(P)-binding Rossmann-like domain 21 88 1.4E-10 T 11-10-2018 AFK25_00785 f26d8bf2984c0357f92b39f01823e8ea 232 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 38 221 5.0E-49 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 AFK25_00785 f26d8bf2984c0357f92b39f01823e8ea 232 SUPERFAMILY SSF53187 36 224 1.29E-51 T 11-10-2018 AFK25_00785 f26d8bf2984c0357f92b39f01823e8ea 232 TIGRFAM TIGR02883 spore_cwlD: N-acetylmuramoyl-L-alanine amidase CwlD 36 223 1.3E-82 T 11-10-2018 IPR014234 N-acetylmuramoyl-L-alanine amidase CwlD MetaCyc: PWY-7883 AFK25_00785 f26d8bf2984c0357f92b39f01823e8ea 232 SMART SM00646 110 221 4.5E-33 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 AFK25_00785 f26d8bf2984c0357f92b39f01823e8ea 232 Gene3D G3DSA:3.40.630.40 31 230 4.5E-56 T 11-10-2018 AFK25_08645 b1755e64007528ad1d5c09cc9881fd33 406 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 318 339 7.2E-84 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 AFK25_08645 b1755e64007528ad1d5c09cc9881fd33 406 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 295 315 7.2E-84 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 AFK25_08645 b1755e64007528ad1d5c09cc9881fd33 406 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 74 93 7.2E-84 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 AFK25_08645 b1755e64007528ad1d5c09cc9881fd33 406 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 383 402 7.2E-84 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 AFK25_08645 b1755e64007528ad1d5c09cc9881fd33 406 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 150 172 7.2E-84 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 AFK25_08645 b1755e64007528ad1d5c09cc9881fd33 406 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 9 26 7.2E-84 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 AFK25_08645 b1755e64007528ad1d5c09cc9881fd33 406 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 239 258 7.2E-84 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 AFK25_08645 b1755e64007528ad1d5c09cc9881fd33 406 PRINTS PR00919 Thermophilic metalloprotease (M29) signature 357 379 7.2E-84 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 AFK25_08645 b1755e64007528ad1d5c09cc9881fd33 406 SUPERFAMILY SSF144052 1 403 2.49E-151 T 11-10-2018 AFK25_08645 b1755e64007528ad1d5c09cc9881fd33 406 Gene3D G3DSA:3.40.1830.10 1 174 1.6E-69 T 11-10-2018 IPR035097 Peptidase M29, N-terminal AFK25_08645 b1755e64007528ad1d5c09cc9881fd33 406 Pfam PF02073 Thermophilic metalloprotease (M29) 2 402 3.0E-180 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 AFK25_00960 127754f5b23ccff9cd225ca45792ee73 208 Pfam PF00072 Response regulator receiver domain 4 115 7.9E-24 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_00960 127754f5b23ccff9cd225ca45792ee73 208 SMART SM00448 2 115 3.1E-26 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_00960 127754f5b23ccff9cd225ca45792ee73 208 SUPERFAMILY SSF52172 2 135 1.04E-32 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_00960 127754f5b23ccff9cd225ca45792ee73 208 SMART SM00421 144 201 6.1E-28 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_00960 127754f5b23ccff9cd225ca45792ee73 208 Pfam PF00196 Bacterial regulatory proteins, luxR family 146 201 3.6E-23 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_00960 127754f5b23ccff9cd225ca45792ee73 208 ProSitePatterns PS00622 LuxR-type HTH domain signature. 161 188 - T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_00960 127754f5b23ccff9cd225ca45792ee73 208 SUPERFAMILY SSF46894 138 207 3.27E-25 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFK25_00960 127754f5b23ccff9cd225ca45792ee73 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 161 177 4.6E-16 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_00960 127754f5b23ccff9cd225ca45792ee73 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 189 4.6E-16 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_00960 127754f5b23ccff9cd225ca45792ee73 208 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 147 161 4.6E-16 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_00960 127754f5b23ccff9cd225ca45792ee73 208 Gene3D G3DSA:3.40.50.12740 2 207 2.1E-77 T 11-10-2018 AFK25_09580 fd6ad271c443dde601a93d2f8b4b0273 474 SUPERFAMILY SSF48695 33 439 2.04E-151 T 11-10-2018 IPR036280 Multiheme cytochrome superfamily AFK25_09580 fd6ad271c443dde601a93d2f8b4b0273 474 PIRSF PIRSF000243 5 465 2.5E-144 T 11-10-2018 IPR003321 Cytochrome c552 GO:0006807|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 AFK25_09580 fd6ad271c443dde601a93d2f8b4b0273 474 Pfam PF02335 Cytochrome c552 42 447 1.5E-133 T 11-10-2018 IPR003321 Cytochrome c552 GO:0006807|GO:0042279|GO:0042597|GO:0055114 KEGG: 00910+1.7.2.2|MetaCyc: PWY-5674 AFK25_09580 fd6ad271c443dde601a93d2f8b4b0273 474 Gene3D G3DSA:1.20.140.10 324 423 5.2E-146 T 11-10-2018 AFK25_09580 fd6ad271c443dde601a93d2f8b4b0273 474 Gene3D G3DSA:1.10.1130.10 43 323 5.2E-146 T 11-10-2018 AFK25_02945 14e5cb775d973b9b71a81d15be81e7ac 611 SUPERFAMILY SSF51206 2 134 1.1E-15 T 11-10-2018 IPR018490 Cyclic nucleotide-binding-like AFK25_02945 14e5cb775d973b9b71a81d15be81e7ac 611 SUPERFAMILY SSF54631 157 274 8.34E-34 T 11-10-2018 AFK25_02945 14e5cb775d973b9b71a81d15be81e7ac 611 Gene3D G3DSA:3.10.580.10 150 315 5.3E-38 T 11-10-2018 AFK25_02945 14e5cb775d973b9b71a81d15be81e7ac 611 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 498 611 4.5E-20 T 11-10-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding AFK25_02945 14e5cb775d973b9b71a81d15be81e7ac 611 SUPERFAMILY SSF81301 299 398 4.58E-6 T 11-10-2018 AFK25_02945 14e5cb775d973b9b71a81d15be81e7ac 611 Gene3D G3DSA:2.60.120.10 1 140 1.4E-17 T 11-10-2018 IPR014710 RmlC-like jelly roll fold AFK25_02945 14e5cb775d973b9b71a81d15be81e7ac 611 Pfam PF00571 CBS domain 158 212 4.7E-13 T 11-10-2018 IPR000644 CBS domain AFK25_02945 14e5cb775d973b9b71a81d15be81e7ac 611 Pfam PF00571 CBS domain 223 274 4.2E-11 T 11-10-2018 IPR000644 CBS domain AFK25_02945 14e5cb775d973b9b71a81d15be81e7ac 611 Pfam PF00027 Cyclic nucleotide-binding domain 23 115 4.0E-7 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain AFK25_02945 14e5cb775d973b9b71a81d15be81e7ac 611 Pfam PF03445 Putative nucleotidyltransferase DUF294 301 432 3.6E-40 T 11-10-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 AFK25_02945 14e5cb775d973b9b71a81d15be81e7ac 611 SMART SM00100 4 129 7.1E-6 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain AFK25_02945 14e5cb775d973b9b71a81d15be81e7ac 611 SMART SM00116 165 212 2.1E-10 T 11-10-2018 IPR000644 CBS domain AFK25_02945 14e5cb775d973b9b71a81d15be81e7ac 611 SMART SM00116 229 276 0.018 T 11-10-2018 IPR000644 CBS domain AFK25_13865 c41f499bdae2d394ef3000be6c34137a 236 SUPERFAMILY SSF81336 70 228 6.28E-41 T 11-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13865 c41f499bdae2d394ef3000be6c34137a 236 Gene3D G3DSA:1.20.120.220 71 236 4.2E-41 T 11-10-2018 IPR035908 ATP synthase, F0 complex, subunit A superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13865 c41f499bdae2d394ef3000be6c34137a 236 ProSitePatterns PS00449 ATP synthase a subunit signature. 165 174 - T 11-10-2018 IPR023011 ATP synthase, F0 complex, subunit A, active site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13865 c41f499bdae2d394ef3000be6c34137a 236 TIGRFAM TIGR01131 ATP_synt_6_or_A: ATP synthase F0, A subunit 15 231 2.9E-48 T 11-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13865 c41f499bdae2d394ef3000be6c34137a 236 PRINTS PR00123 ATP synthase A subunit signature 162 184 3.7E-19 T 11-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13865 c41f499bdae2d394ef3000be6c34137a 236 PRINTS PR00123 ATP synthase A subunit signature 78 94 3.7E-19 T 11-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13865 c41f499bdae2d394ef3000be6c34137a 236 PRINTS PR00123 ATP synthase A subunit signature 215 230 3.7E-19 T 11-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13865 c41f499bdae2d394ef3000be6c34137a 236 PRINTS PR00123 ATP synthase A subunit signature 146 161 3.7E-19 T 11-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13865 c41f499bdae2d394ef3000be6c34137a 236 Pfam PF00119 ATP synthase A chain 20 228 2.3E-59 T 11-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13865 c41f499bdae2d394ef3000be6c34137a 236 Hamap MF_01393 ATP synthase subunit a [atpB]. 1 235 13.859 T 11-10-2018 IPR000568 ATP synthase, F0 complex, subunit A GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_10415 fba379e7ce9dcd1ef5a09c7cbca33dad 367 ProDom PD041835 PROTEASE GERMINATION HYDROLASE SPORE GPR ENDOPEPTIDASE PROTEINASE ZYMOGEN PRECURSOR PEPTIDASE 7 367 1.0E-155 T 11-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 AFK25_10415 fba379e7ce9dcd1ef5a09c7cbca33dad 367 TIGRFAM TIGR01441 GPR: GPR endopeptidase 7 367 2.1E-173 T 11-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 AFK25_10415 fba379e7ce9dcd1ef5a09c7cbca33dad 367 PIRSF PIRSF019549 1 367 9.6E-178 T 11-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 AFK25_10415 fba379e7ce9dcd1ef5a09c7cbca33dad 367 Hamap MF_00626 Germination protease [gpr]. 1 367 156.217 T 11-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 AFK25_10415 fba379e7ce9dcd1ef5a09c7cbca33dad 367 SUPERFAMILY SSF53163 4 367 2.38E-130 T 11-10-2018 IPR023430 Peptidase HybD-like domain superfamily AFK25_10415 fba379e7ce9dcd1ef5a09c7cbca33dad 367 Gene3D G3DSA:3.40.50.1450 1 367 6.6E-131 T 11-10-2018 IPR023430 Peptidase HybD-like domain superfamily AFK25_10415 fba379e7ce9dcd1ef5a09c7cbca33dad 367 Pfam PF03418 Germination protease 14 366 4.0E-190 T 11-10-2018 IPR005080 Peptidase A25, germination protease GO:0006508|GO:0008233|GO:0009847 AFK25_11505 dec6442cbe587f4bdb0cab659d0f6d96 361 Gene3D G3DSA:3.40.630.10 12 345 9.2E-140 T 11-10-2018 AFK25_11505 dec6442cbe587f4bdb0cab659d0f6d96 361 Gene3D G3DSA:2.40.30.40 77 164 9.2E-140 T 11-10-2018 IPR023367 Peptidase M42, domain 2 AFK25_11505 dec6442cbe587f4bdb0cab659d0f6d96 361 PIRSF PIRSF001123 4 361 2.2E-151 T 11-10-2018 IPR008007 Peptidase M42 AFK25_11505 dec6442cbe587f4bdb0cab659d0f6d96 361 SUPERFAMILY SSF101821 73 182 3.82E-33 T 11-10-2018 AFK25_11505 dec6442cbe587f4bdb0cab659d0f6d96 361 SUPERFAMILY SSF53187 6 358 4.28E-74 T 11-10-2018 AFK25_11505 dec6442cbe587f4bdb0cab659d0f6d96 361 Pfam PF05343 M42 glutamyl aminopeptidase 48 342 1.1E-117 T 11-10-2018 IPR008007 Peptidase M42 AFK25_10365 799241038186d2b0eeb945b950a659de 249 Gene3D G3DSA:2.40.240.20 1 71 5.9E-22 T 11-10-2018 AFK25_10365 799241038186d2b0eeb945b950a659de 249 SUPERFAMILY SSF88697 2 68 1.44E-17 T 11-10-2018 IPR015947 PUA-like superfamily AFK25_10365 799241038186d2b0eeb945b950a659de 249 Pfam PF04452 RNA methyltransferase 17 244 1.5E-73 T 11-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 AFK25_10365 799241038186d2b0eeb945b950a659de 249 TIGRFAM TIGR00046 TIGR00046: RNA methyltransferase, RsmE family 4 245 6.1E-69 T 11-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 AFK25_10365 799241038186d2b0eeb945b950a659de 249 SUPERFAMILY SSF75217 71 247 1.31E-55 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases AFK25_10365 799241038186d2b0eeb945b950a659de 249 Gene3D G3DSA:3.40.1280.10 72 249 6.5E-65 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFK25_10365 799241038186d2b0eeb945b950a659de 249 PIRSF PIRSF015601 1 248 1.1E-63 T 11-10-2018 IPR006700 Ribosomal RNA small subunit methyltransferase E GO:0006364|GO:0008168 AFK25_12180 5cacd71155ee7a2e425c730130af4652 145 PIRSF PIRSF005900 1 145 6.9E-50 T 11-10-2018 IPR002177 DNA-binding protein Dps AFK25_12180 5cacd71155ee7a2e425c730130af4652 145 Gene3D G3DSA:1.20.1260.10 1 145 1.1E-56 T 11-10-2018 IPR012347 Ferritin-like AFK25_12180 5cacd71155ee7a2e425c730130af4652 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 27 43 3.5E-16 T 11-10-2018 IPR002177 DNA-binding protein Dps AFK25_12180 5cacd71155ee7a2e425c730130af4652 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 122 140 3.5E-16 T 11-10-2018 IPR002177 DNA-binding protein Dps AFK25_12180 5cacd71155ee7a2e425c730130af4652 145 PRINTS PR01346 Helicobacter neutrophil-activating protein A family signature 51 67 3.5E-16 T 11-10-2018 IPR002177 DNA-binding protein Dps AFK25_12180 5cacd71155ee7a2e425c730130af4652 145 ProSitePatterns PS00819 Dps protein family signature 2. 53 67 - T 11-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 AFK25_12180 5cacd71155ee7a2e425c730130af4652 145 Pfam PF00210 Ferritin-like domain 7 144 2.8E-36 T 11-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 AFK25_12180 5cacd71155ee7a2e425c730130af4652 145 ProSitePatterns PS00818 Dps protein family signature 1. 27 43 - T 11-10-2018 IPR023188 DNA-binding protein Dps, conserved site GO:0016722|GO:0055114 AFK25_12180 5cacd71155ee7a2e425c730130af4652 145 SUPERFAMILY SSF47240 3 145 3.29E-49 T 11-10-2018 IPR009078 Ferritin-like superfamily AFK25_04035 a95fb564a663496eec7958b66cdcc014 598 Pfam PF00005 ABC transporter 370 518 1.1E-35 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_04035 a95fb564a663496eec7958b66cdcc014 598 Gene3D G3DSA:1.20.1560.10 2 340 1.4E-106 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFK25_04035 a95fb564a663496eec7958b66cdcc014 598 SUPERFAMILY SSF90123 18 338 8.89E-82 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFK25_04035 a95fb564a663496eec7958b66cdcc014 598 ProSitePatterns PS00211 ABC transporters family signature. 490 504 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_04035 a95fb564a663496eec7958b66cdcc014 598 Gene3D G3DSA:3.40.50.300 349 595 5.1E-94 T 11-10-2018 AFK25_04035 a95fb564a663496eec7958b66cdcc014 598 SUPERFAMILY SSF52540 342 586 6.92E-94 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_04035 a95fb564a663496eec7958b66cdcc014 598 Pfam PF00664 ABC transporter transmembrane region 38 308 1.6E-57 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFK25_04035 a95fb564a663496eec7958b66cdcc014 598 SMART SM00382 378 564 1.3E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_11345 f7c03f748fa5917ef7e6fe212a558eb3 569 Gene3D G3DSA:3.30.460.10 154 260 3.1E-21 T 11-10-2018 AFK25_11345 f7c03f748fa5917ef7e6fe212a558eb3 569 SUPERFAMILY SSF81301 154 316 1.11E-42 T 11-10-2018 AFK25_11345 f7c03f748fa5917ef7e6fe212a558eb3 569 Gene3D G3DSA:1.10.150.110 1 84 1.1E-17 T 11-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily AFK25_11345 f7c03f748fa5917ef7e6fe212a558eb3 569 Gene3D G3DSA:3.20.20.140 326 569 2.5E-75 T 11-10-2018 AFK25_11345 f7c03f748fa5917ef7e6fe212a558eb3 569 SUPERFAMILY SSF89550 335 565 1.14E-55 T 11-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFK25_11345 f7c03f748fa5917ef7e6fe212a558eb3 569 Pfam PF14716 Helix-hairpin-helix domain 6 71 1.7E-18 T 11-10-2018 IPR010996 DNA polymerase beta-like, N-terminal domain AFK25_11345 f7c03f748fa5917ef7e6fe212a558eb3 569 Gene3D G3DSA:1.10.150.20 85 150 1.3E-19 T 11-10-2018 AFK25_11345 f7c03f748fa5917ef7e6fe212a558eb3 569 SUPERFAMILY SSF47802 6 83 1.7E-19 T 11-10-2018 IPR027421 DNA polymerase lambda lyase domain superfamily AFK25_11345 f7c03f748fa5917ef7e6fe212a558eb3 569 Gene3D G3DSA:3.30.210.10 261 325 2.1E-16 T 11-10-2018 IPR037160 DNA polymerase, thumb domain superfamily AFK25_11345 f7c03f748fa5917ef7e6fe212a558eb3 569 SMART SM00481 337 416 1.9E-19 T 11-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal AFK25_11345 f7c03f748fa5917ef7e6fe212a558eb3 569 Pfam PF14520 Helix-hairpin-helix domain 92 145 1.0E-5 T 11-10-2018 AFK25_11345 f7c03f748fa5917ef7e6fe212a558eb3 569 Pfam PF02811 PHP domain 338 427 7.6E-8 T 11-10-2018 IPR004013 PHP domain GO:0003824 AFK25_11345 f7c03f748fa5917ef7e6fe212a558eb3 569 Pfam PF14791 DNA polymerase beta thumb 255 316 5.2E-18 T 11-10-2018 IPR029398 DNA polymerase beta, thumb domain AFK25_11345 f7c03f748fa5917ef7e6fe212a558eb3 569 PIRSF PIRSF005047 3 569 3.3E-234 T 11-10-2018 IPR022311 Uncharacterised conserved protein UCP005047, YshC KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_11345 f7c03f748fa5917ef7e6fe212a558eb3 569 SMART SM00483 2 316 1.9E-63 T 11-10-2018 IPR002054 DNA-directed DNA polymerase X GO:0003677|GO:0003887 AFK25_08450 2cae9e5c2b4dbdf525d0289efaeeeea1 497 SUPERFAMILY SSF75005 23 335 2.98E-121 T 11-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFK25_08450 2cae9e5c2b4dbdf525d0289efaeeeea1 497 Gene3D G3DSA:2.60.120.560 347 494 4.1E-38 T 11-10-2018 AFK25_08450 2cae9e5c2b4dbdf525d0289efaeeeea1 497 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 18 464 2.1E-153 T 11-10-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 AFK25_08450 2cae9e5c2b4dbdf525d0289efaeeeea1 497 SUPERFAMILY SSF49899 334 494 2.22E-36 T 11-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFK25_08450 2cae9e5c2b4dbdf525d0289efaeeeea1 497 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 337 488 1.3E-30 T 11-10-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal AFK25_08450 2cae9e5c2b4dbdf525d0289efaeeeea1 497 Gene3D G3DSA:2.115.10.20 1 346 1.0E-134 T 11-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFK25_08450 2cae9e5c2b4dbdf525d0289efaeeeea1 497 SMART SM00640 31 454 2.3E-154 T 11-10-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 AFK25_08450 2cae9e5c2b4dbdf525d0289efaeeeea1 497 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 31 334 3.1E-111 T 11-10-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal AFK25_06705 d92bc003b61b0f5c8342b37d579f2542 82 PIRSF PIRSF004764 1 82 1.2E-31 T 11-10-2018 IPR024702 Uncharacterised conserved protein YmfJ AFK25_06705 d92bc003b61b0f5c8342b37d579f2542 82 Pfam PF11588 Protein of unknown function (DUF3243) 3 80 5.5E-37 T 11-10-2018 IPR021637 Protein of unknown function DUF3243 AFK25_06705 d92bc003b61b0f5c8342b37d579f2542 82 Gene3D G3DSA:1.10.760.20 1 82 7.2E-34 T 11-10-2018 IPR038292 YmfJ/YflH superfamily AFK25_05605 8afa4a153c29082cbcd2fa4a8532170b 386 Gene3D G3DSA:3.40.50.261 240 386 1.2E-58 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFK25_05605 8afa4a153c29082cbcd2fa4a8532170b 386 SUPERFAMILY SSF56059 1 238 2.79E-87 T 11-10-2018 AFK25_05605 8afa4a153c29082cbcd2fa4a8532170b 386 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 385 1.8E-168 T 11-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFK25_05605 8afa4a153c29082cbcd2fa4a8532170b 386 SUPERFAMILY SSF52210 239 385 7.33E-56 T 11-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFK25_05605 8afa4a153c29082cbcd2fa4a8532170b 386 Gene3D G3DSA:3.30.470.20 1 234 1.1E-98 T 11-10-2018 AFK25_05605 8afa4a153c29082cbcd2fa4a8532170b 386 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 257 282 - T 11-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFK25_05605 8afa4a153c29082cbcd2fa4a8532170b 386 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 386 45.706 T 11-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFK25_05605 8afa4a153c29082cbcd2fa4a8532170b 386 Gene3D G3DSA:3.30.1490.20 21 104 1.1E-98 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFK25_05605 8afa4a153c29082cbcd2fa4a8532170b 386 Pfam PF08442 ATP-grasp domain 2 203 1.1E-83 T 11-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFK25_05605 8afa4a153c29082cbcd2fa4a8532170b 386 PIRSF PIRSF001554 1 386 1.0E-158 T 11-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFK25_05605 8afa4a153c29082cbcd2fa4a8532170b 386 Pfam PF00549 CoA-ligase 262 380 1.5E-26 T 11-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AFK25_03240 f44cbf1d65abe5cf31d674fb310d69d9 506 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 5 247 2.9E-102 T 11-10-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 AFK25_03240 f44cbf1d65abe5cf31d674fb310d69d9 506 Gene3D G3DSA:3.30.950.10 118 248 1.1E-53 T 11-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFK25_03240 f44cbf1d65abe5cf31d674fb310d69d9 506 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 373 482 1.2E-8 T 11-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFK25_03240 f44cbf1d65abe5cf31d674fb310d69d9 506 SUPERFAMILY SSF53790 1 252 5.1E-59 T 11-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFK25_03240 f44cbf1d65abe5cf31d674fb310d69d9 506 Gene3D G3DSA:3.30.413.10 368 497 5.4E-18 T 11-10-2018 AFK25_03240 f44cbf1d65abe5cf31d674fb310d69d9 506 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 406 422 - T 11-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFK25_03240 f44cbf1d65abe5cf31d674fb310d69d9 506 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 214 2.6E-39 T 11-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFK25_03240 f44cbf1d65abe5cf31d674fb310d69d9 506 Gene3D G3DSA:3.40.1010.10 1 117 1.8E-34 T 11-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFK25_03240 f44cbf1d65abe5cf31d674fb310d69d9 506 SUPERFAMILY SSF56014 371 484 7.07E-21 T 11-10-2018 AFK25_14645 12f19117dbac573a7485cc6d0133f295 461 Pfam PF01926 50S ribosome-binding GTPase 227 338 9.3E-25 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_14645 12f19117dbac573a7485cc6d0133f295 461 Gene3D G3DSA:3.30.1360.120 1 126 3.5E-48 T 11-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 AFK25_14645 12f19117dbac573a7485cc6d0133f295 461 PRINTS PR00449 Transforming protein P21 ras signature 224 245 8.3E-5 T 11-10-2018 AFK25_14645 12f19117dbac573a7485cc6d0133f295 461 PRINTS PR00449 Transforming protein P21 ras signature 264 286 8.3E-5 T 11-10-2018 AFK25_14645 12f19117dbac573a7485cc6d0133f295 461 PRINTS PR00449 Transforming protein P21 ras signature 328 341 8.3E-5 T 11-10-2018 AFK25_14645 12f19117dbac573a7485cc6d0133f295 461 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 227 374 1.0E-29 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFK25_14645 12f19117dbac573a7485cc6d0133f295 461 SUPERFAMILY SSF116878 127 461 1.12E-50 T 11-10-2018 AFK25_14645 12f19117dbac573a7485cc6d0133f295 461 Gene3D G3DSA:1.20.120.430 127 461 1.5E-109 T 11-10-2018 IPR027368 tRNA modification GTPase MnmE domain 2 Reactome: R-HSA-6787450 AFK25_14645 12f19117dbac573a7485cc6d0133f295 461 SUPERFAMILY SSF52540 80 378 4.41E-47 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_14645 12f19117dbac573a7485cc6d0133f295 461 Pfam PF10396 GTP-binding protein TrmE N-terminus 5 126 2.3E-41 T 11-10-2018 IPR018948 GTP-binding protein TrmE, N-terminal Reactome: R-HSA-6787450 AFK25_14645 12f19117dbac573a7485cc6d0133f295 461 Hamap MF_00379 tRNA modification GTPase MnmE [mnmE]. 4 461 34.523 T 11-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 AFK25_14645 12f19117dbac573a7485cc6d0133f295 461 TIGRFAM TIGR00450 mnmE_trmE_thdF: tRNA modification GTPase TrmE 11 461 8.7E-138 T 11-10-2018 IPR004520 tRNA modification GTPase MnmE GO:0003924|GO:0005525|GO:0005622|GO:0006400 Reactome: R-HSA-6787450 AFK25_14645 12f19117dbac573a7485cc6d0133f295 461 Pfam PF12631 MnmE helical domain 129 458 5.9E-61 T 11-10-2018 IPR025867 MnmE, helical domain Reactome: R-HSA-6787450 AFK25_14645 12f19117dbac573a7485cc6d0133f295 461 Gene3D G3DSA:3.40.50.300 224 389 1.5E-109 T 11-10-2018 AFK25_11070 bb7fe89c74b0b15c835b811782470aad 434 TIGRFAM TIGR01499 folC: bifunctional protein FolC 24 428 1.7E-130 T 11-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 AFK25_11070 bb7fe89c74b0b15c835b811782470aad 434 ProSitePatterns PS01011 Folylpolyglutamate synthase signature 1. 44 67 - T 11-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 AFK25_11070 bb7fe89c74b0b15c835b811782470aad 434 PIRSF PIRSF001563 1 434 9.4E-159 T 11-10-2018 IPR001645 Folylpolyglutamate synthetase GO:0004326|GO:0005524|GO:0009396 KEGG: 00790+6.3.2.17|MetaCyc: PWY-2161|Reactome: R-HSA-196757 AFK25_11070 bb7fe89c74b0b15c835b811782470aad 434 SUPERFAMILY SSF53244 301 432 4.21E-30 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFK25_11070 bb7fe89c74b0b15c835b811782470aad 434 ProSitePatterns PS01012 Folylpolyglutamate synthase signature 2. 143 158 - T 11-10-2018 IPR018109 Folylpolyglutamate synthetase, conserved site GO:0004326|GO:0005524|GO:0009396 Reactome: R-HSA-196757 AFK25_11070 bb7fe89c74b0b15c835b811782470aad 434 Gene3D G3DSA:3.40.1190.10 1 299 2.0E-101 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFK25_11070 bb7fe89c74b0b15c835b811782470aad 434 Gene3D G3DSA:3.90.190.20 301 434 1.4E-33 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFK25_11070 bb7fe89c74b0b15c835b811782470aad 434 Pfam PF08245 Mur ligase middle domain 46 274 1.8E-16 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 AFK25_11070 bb7fe89c74b0b15c835b811782470aad 434 SUPERFAMILY SSF53623 3 299 2.04E-97 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFK25_11070 bb7fe89c74b0b15c835b811782470aad 434 Pfam PF02875 Mur ligase family, glutamate ligase domain 301 377 5.2E-8 T 11-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 AFK25_10375 dcc3718350a5f2f1e4ed0068117083bc 373 SMART SM00271 4 61 6.6E-32 T 11-10-2018 IPR001623 DnaJ domain AFK25_10375 dcc3718350a5f2f1e4ed0068117083bc 373 Gene3D G3DSA:2.10.230.10 145 209 1.1E-38 T 11-10-2018 AFK25_10375 dcc3718350a5f2f1e4ed0068117083bc 373 SUPERFAMILY SSF57938 132 213 1.31E-19 T 11-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily AFK25_10375 dcc3718350a5f2f1e4ed0068117083bc 373 Hamap MF_01152 Chaperone protein DnaJ [dnaJ]. 2 369 42.038 T 11-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 AFK25_10375 dcc3718350a5f2f1e4ed0068117083bc 373 Gene3D G3DSA:2.60.260.20 115 251 1.1E-38 T 11-10-2018 AFK25_10375 dcc3718350a5f2f1e4ed0068117083bc 373 TIGRFAM TIGR02349 DnaJ_bact: chaperone protein DnaJ 5 351 6.1E-147 T 11-10-2018 IPR012724 Chaperone DnaJ GO:0005524|GO:0006457|GO:0009408|GO:0051082 AFK25_10375 dcc3718350a5f2f1e4ed0068117083bc 373 Pfam PF00684 DnaJ central domain 145 209 2.3E-14 T 11-10-2018 IPR001305 Heat shock protein DnaJ, cysteine-rich domain GO:0031072|GO:0051082 AFK25_10375 dcc3718350a5f2f1e4ed0068117083bc 373 PRINTS PR00625 DnaJ domain signature 61 80 7.3E-30 T 11-10-2018 IPR001623 DnaJ domain AFK25_10375 dcc3718350a5f2f1e4ed0068117083bc 373 PRINTS PR00625 DnaJ domain signature 7 25 7.3E-30 T 11-10-2018 IPR001623 DnaJ domain AFK25_10375 dcc3718350a5f2f1e4ed0068117083bc 373 PRINTS PR00625 DnaJ domain signature 25 40 7.3E-30 T 11-10-2018 IPR001623 DnaJ domain AFK25_10375 dcc3718350a5f2f1e4ed0068117083bc 373 PRINTS PR00625 DnaJ domain signature 41 61 7.3E-30 T 11-10-2018 IPR001623 DnaJ domain AFK25_10375 dcc3718350a5f2f1e4ed0068117083bc 373 ProSitePatterns PS00636 Nt-dnaJ domain signature. 46 65 - T 11-10-2018 IPR018253 DnaJ domain, conserved site AFK25_10375 dcc3718350a5f2f1e4ed0068117083bc 373 SUPERFAMILY SSF49493 112 262 3.92E-20 T 11-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 AFK25_10375 dcc3718350a5f2f1e4ed0068117083bc 373 SUPERFAMILY SSF49493 260 346 3.4E-26 T 11-10-2018 IPR008971 HSP40/DnaJ peptide-binding GO:0006457|GO:0051082 AFK25_10375 dcc3718350a5f2f1e4ed0068117083bc 373 Pfam PF01556 DnaJ C terminal domain 118 335 2.5E-47 T 11-10-2018 IPR002939 Chaperone DnaJ, C-terminal AFK25_10375 dcc3718350a5f2f1e4ed0068117083bc 373 Gene3D G3DSA:1.10.287.110 1 111 2.4E-40 T 11-10-2018 IPR036869 Chaperone J-domain superfamily AFK25_10375 dcc3718350a5f2f1e4ed0068117083bc 373 Pfam PF00226 DnaJ domain 5 66 4.1E-28 T 11-10-2018 IPR001623 DnaJ domain AFK25_10375 dcc3718350a5f2f1e4ed0068117083bc 373 SUPERFAMILY SSF46565 1 103 4.84E-37 T 11-10-2018 IPR036869 Chaperone J-domain superfamily AFK25_10375 dcc3718350a5f2f1e4ed0068117083bc 373 Gene3D G3DSA:2.60.260.20 256 363 1.4E-33 T 11-10-2018 AFK25_04050 b1b3c62a7d10ca250662df78f667465e 220 Gene3D G3DSA:1.20.58.1910 102 219 3.3E-47 T 11-10-2018 AFK25_04050 b1b3c62a7d10ca250662df78f667465e 220 Pfam PF01966 HD domain 29 126 6.8E-7 T 11-10-2018 IPR006674 HD domain AFK25_04050 b1b3c62a7d10ca250662df78f667465e 220 SUPERFAMILY SSF109604 1 213 4.0E-73 T 11-10-2018 AFK25_04050 b1b3c62a7d10ca250662df78f667465e 220 SMART SM00471 22 136 2.9E-6 T 11-10-2018 IPR003607 HD/PDEase domain AFK25_04050 b1b3c62a7d10ca250662df78f667465e 220 Gene3D G3DSA:1.10.472.50 1 99 6.0E-35 T 11-10-2018 AFK25_09820 900c646cdeb75debea22c71ea4253d4b 630 Pfam PF13292 1-deoxy-D-xylulose-5-phosphate synthase 5 278 7.0E-121 T 11-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFK25_09820 900c646cdeb75debea22c71ea4253d4b 630 Gene3D G3DSA:3.40.50.970 313 489 1.8E-65 T 11-10-2018 AFK25_09820 900c646cdeb75debea22c71ea4253d4b 630 Pfam PF02779 Transketolase, pyrimidine binding domain 316 477 2.9E-39 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFK25_09820 900c646cdeb75debea22c71ea4253d4b 630 SUPERFAMILY SSF52518 314 503 5.89E-55 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold AFK25_09820 900c646cdeb75debea22c71ea4253d4b 630 SMART SM00861 316 481 1.5E-63 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFK25_09820 900c646cdeb75debea22c71ea4253d4b 630 SUPERFAMILY SSF52518 6 378 2.02E-76 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold AFK25_09820 900c646cdeb75debea22c71ea4253d4b 630 Hamap MF_00315 1-deoxy-D-xylulose-5-phosphate synthase [dxs]. 2 624 45.646 T 11-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFK25_09820 900c646cdeb75debea22c71ea4253d4b 630 ProSitePatterns PS00801 Transketolase signature 1. 28 47 - T 11-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFK25_09820 900c646cdeb75debea22c71ea4253d4b 630 TIGRFAM TIGR00204 dxs: 1-deoxy-D-xylulose-5-phosphate synthase 4 620 5.3E-302 T 11-10-2018 IPR005477 Deoxyxylulose-5-phosphate synthase GO:0008661|GO:0016114 KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFK25_09820 900c646cdeb75debea22c71ea4253d4b 630 ProSitePatterns PS00802 Transketolase signature 2. 422 438 - T 11-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFK25_09820 900c646cdeb75debea22c71ea4253d4b 630 Pfam PF02780 Transketolase, C-terminal domain 493 615 7.3E-35 T 11-10-2018 IPR033248 Transketolase, C-terminal domain AFK25_09820 900c646cdeb75debea22c71ea4253d4b 630 Gene3D G3DSA:3.40.50.920 493 626 3.4E-41 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFK25_09820 900c646cdeb75debea22c71ea4253d4b 630 SUPERFAMILY SSF52922 490 619 8.51E-37 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFK25_10075 6e29fad457cd1946e1fb85eccd72e93f 620 Gene3D G3DSA:3.40.720.10 233 542 1.9E-76 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFK25_10075 6e29fad457cd1946e1fb85eccd72e93f 620 PIRSF PIRSF005091 1 615 6.0E-197 T 11-10-2018 IPR012160 Lipoteichoic acid synthase-like AFK25_10075 6e29fad457cd1946e1fb85eccd72e93f 620 Pfam PF00884 Sulfatase 240 532 6.7E-35 T 11-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 AFK25_10075 6e29fad457cd1946e1fb85eccd72e93f 620 SUPERFAMILY SSF53649 238 613 9.0E-73 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AFK25_03260 9288bcc6bdef56c16fb0786cdd693ea3 370 PIRSF PIRSF026782 2 363 1.7E-127 T 11-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 AFK25_03260 9288bcc6bdef56c16fb0786cdd693ea3 370 Pfam PF01888 CbiD 6 265 3.7E-98 T 11-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 AFK25_03260 9288bcc6bdef56c16fb0786cdd693ea3 370 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 6 356 29.342 T 11-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 AFK25_03260 9288bcc6bdef56c16fb0786cdd693ea3 370 Gene3D G3DSA:3.30.2110.10 8 179 1.1E-52 T 11-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 AFK25_03260 9288bcc6bdef56c16fb0786cdd693ea3 370 SUPERFAMILY SSF111342 3 283 7.98E-87 T 11-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 AFK25_03260 9288bcc6bdef56c16fb0786cdd693ea3 370 TIGRFAM TIGR00312 cbiD: cobalamin biosynthesis protein CbiD 13 327 4.0E-68 T 11-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 AFK25_11045 ab1d543230f9ce450c56cef75eade5f7 196 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 13 33 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_11045 ab1d543230f9ce450c56cef75eade5f7 196 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 12 32 3.0E-6 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_11045 ab1d543230f9ce450c56cef75eade5f7 196 Pfam PF07963 Prokaryotic N-terminal methylation motif 11 34 5.9E-8 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_01660 8c93939821ed0244117128931433afc3 632 SMART SM00471 454 591 9.6E-5 T 11-10-2018 IPR003607 HD/PDEase domain AFK25_01660 8c93939821ed0244117128931433afc3 632 Gene3D G3DSA:1.10.3210.10 435 632 1.0E-70 T 11-10-2018 AFK25_01660 8c93939821ed0244117128931433afc3 632 SUPERFAMILY SSF46458 10 152 1.39E-27 T 11-10-2018 IPR009050 Globin-like superfamily AFK25_01660 8c93939821ed0244117128931433afc3 632 SUPERFAMILY SSF109604 447 622 1.26E-37 T 11-10-2018 AFK25_01660 8c93939821ed0244117128931433afc3 632 Gene3D G3DSA:1.10.490.10 2 153 1.0E-33 T 11-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 AFK25_01660 8c93939821ed0244117128931433afc3 632 Pfam PF13487 HD domain 509 572 3.8E-17 T 11-10-2018 AFK25_01660 8c93939821ed0244117128931433afc3 632 Pfam PF11563 Protoglobin 13 158 2.6E-29 T 11-10-2018 AFK25_11715 d0da9802243203a8e121d7fbed732d84 458 Gene3D G3DSA:1.20.200.10 120 449 2.0E-199 T 11-10-2018 AFK25_11715 d0da9802243203a8e121d7fbed732d84 458 Gene3D G3DSA:1.10.40.30 361 433 2.0E-199 T 11-10-2018 AFK25_11715 d0da9802243203a8e121d7fbed732d84 458 ProSitePatterns PS00163 Fumarate lyases signature. 276 285 - T 11-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 AFK25_11715 d0da9802243203a8e121d7fbed732d84 458 PRINTS PR00149 Fumarate lyase superfamily signature 103 121 3.2E-29 T 11-10-2018 IPR000362 Fumarate lyase family AFK25_11715 d0da9802243203a8e121d7fbed732d84 458 PRINTS PR00149 Fumarate lyase superfamily signature 148 166 3.2E-29 T 11-10-2018 IPR000362 Fumarate lyase family AFK25_11715 d0da9802243203a8e121d7fbed732d84 458 PRINTS PR00149 Fumarate lyase superfamily signature 232 259 3.2E-29 T 11-10-2018 IPR000362 Fumarate lyase family AFK25_11715 d0da9802243203a8e121d7fbed732d84 458 PRINTS PR00149 Fumarate lyase superfamily signature 276 292 3.2E-29 T 11-10-2018 IPR000362 Fumarate lyase family AFK25_11715 d0da9802243203a8e121d7fbed732d84 458 Gene3D G3DSA:1.10.275.10 26 230 2.0E-199 T 11-10-2018 IPR024083 Fumarase/histidase, N-terminal AFK25_11715 d0da9802243203a8e121d7fbed732d84 458 TIGRFAM TIGR00838 argH: argininosuccinate lyase 4 456 2.4E-212 T 11-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFK25_11715 d0da9802243203a8e121d7fbed732d84 458 SUPERFAMILY SSF48557 4 456 6.75E-154 T 11-10-2018 IPR008948 L-Aspartase-like GO:0003824 AFK25_11715 d0da9802243203a8e121d7fbed732d84 458 PRINTS PR00145 Argininosuccinate lyase family signature 232 256 4.0E-70 T 11-10-2018 AFK25_11715 d0da9802243203a8e121d7fbed732d84 458 PRINTS PR00145 Argininosuccinate lyase family signature 311 330 4.0E-70 T 11-10-2018 AFK25_11715 d0da9802243203a8e121d7fbed732d84 458 PRINTS PR00145 Argininosuccinate lyase family signature 102 124 4.0E-70 T 11-10-2018 AFK25_11715 d0da9802243203a8e121d7fbed732d84 458 PRINTS PR00145 Argininosuccinate lyase family signature 276 292 4.0E-70 T 11-10-2018 AFK25_11715 d0da9802243203a8e121d7fbed732d84 458 PRINTS PR00145 Argininosuccinate lyase family signature 143 163 4.0E-70 T 11-10-2018 AFK25_11715 d0da9802243203a8e121d7fbed732d84 458 PRINTS PR00145 Argininosuccinate lyase family signature 194 210 4.0E-70 T 11-10-2018 AFK25_11715 d0da9802243203a8e121d7fbed732d84 458 Hamap MF_00006 Argininosuccinate lyase [argH]. 3 454 45.273 T 11-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFK25_11715 d0da9802243203a8e121d7fbed732d84 458 Pfam PF00206 Lyase 7 301 2.4E-77 T 11-10-2018 IPR022761 Fumarate lyase, N-terminal AFK25_11715 d0da9802243203a8e121d7fbed732d84 458 Pfam PF14698 Argininosuccinate lyase C-terminal 364 432 1.8E-25 T 11-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AFK25_13005 54c2158bb155e5ac8cf4a2aeb87d873e 425 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 222 254 - T 11-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 AFK25_13005 54c2158bb155e5ac8cf4a2aeb87d873e 425 Pfam PF00815 Histidinol dehydrogenase 19 420 5.6E-175 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFK25_13005 54c2158bb155e5ac8cf4a2aeb87d873e 425 PIRSF PIRSF000099 3 423 2.9E-173 T 11-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFK25_13005 54c2158bb155e5ac8cf4a2aeb87d873e 425 SUPERFAMILY SSF53720 21 420 1.96E-86 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFK25_13005 54c2158bb155e5ac8cf4a2aeb87d873e 425 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 27 419 1.1E-170 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFK25_13005 54c2158bb155e5ac8cf4a2aeb87d873e 425 PRINTS PR00083 Histidinol dehydrogenase signature 27 51 4.9E-91 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFK25_13005 54c2158bb155e5ac8cf4a2aeb87d873e 425 PRINTS PR00083 Histidinol dehydrogenase signature 313 338 4.9E-91 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFK25_13005 54c2158bb155e5ac8cf4a2aeb87d873e 425 PRINTS PR00083 Histidinol dehydrogenase signature 128 154 4.9E-91 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFK25_13005 54c2158bb155e5ac8cf4a2aeb87d873e 425 PRINTS PR00083 Histidinol dehydrogenase signature 163 189 4.9E-91 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFK25_13005 54c2158bb155e5ac8cf4a2aeb87d873e 425 PRINTS PR00083 Histidinol dehydrogenase signature 244 263 4.9E-91 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFK25_13005 54c2158bb155e5ac8cf4a2aeb87d873e 425 PRINTS PR00083 Histidinol dehydrogenase signature 193 218 4.9E-91 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFK25_13005 54c2158bb155e5ac8cf4a2aeb87d873e 425 PRINTS PR00083 Histidinol dehydrogenase signature 222 243 4.9E-91 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFK25_13005 54c2158bb155e5ac8cf4a2aeb87d873e 425 PRINTS PR00083 Histidinol dehydrogenase signature 354 372 4.9E-91 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFK25_13005 54c2158bb155e5ac8cf4a2aeb87d873e 425 Gene3D G3DSA:3.40.50.1980 25 224 6.1E-130 T 11-10-2018 AFK25_13005 54c2158bb155e5ac8cf4a2aeb87d873e 425 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 1 420 42.754 T 11-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AFK25_13005 54c2158bb155e5ac8cf4a2aeb87d873e 425 Gene3D G3DSA:3.40.50.1980 226 342 6.1E-130 T 11-10-2018 AFK25_10685 25b243a2aa60041e2d2c0a3e321546bc 877 Gene3D G3DSA:3.30.54.20 626 679 1.4E-52 T 11-10-2018 AFK25_10685 25b243a2aa60041e2d2c0a3e321546bc 877 SUPERFAMILY SSF55186 554 720 6.54E-54 T 11-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 AFK25_10685 25b243a2aa60041e2d2c0a3e321546bc 877 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 655 698 1.4E-18 T 11-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 AFK25_10685 25b243a2aa60041e2d2c0a3e321546bc 877 SUPERFAMILY SSF55681 5 245 4.47E-90 T 11-10-2018 AFK25_10685 25b243a2aa60041e2d2c0a3e321546bc 877 SMART SM00863 655 698 1.3E-21 T 11-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 AFK25_10685 25b243a2aa60041e2d2c0a3e321546bc 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 300 313 3.5E-32 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFK25_10685 25b243a2aa60041e2d2c0a3e321546bc 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 226 239 3.5E-32 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFK25_10685 25b243a2aa60041e2d2c0a3e321546bc 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 199 210 3.5E-32 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFK25_10685 25b243a2aa60041e2d2c0a3e321546bc 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 276 292 3.5E-32 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFK25_10685 25b243a2aa60041e2d2c0a3e321546bc 877 PRINTS PR00980 Alanyl-tRNA synthetase signature 73 84 3.5E-32 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFK25_10685 25b243a2aa60041e2d2c0a3e321546bc 877 Gene3D G3DSA:3.10.310.40 765 876 2.1E-36 T 11-10-2018 AFK25_10685 25b243a2aa60041e2d2c0a3e321546bc 877 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 8 857 0.0 T 11-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AFK25_10685 25b243a2aa60041e2d2c0a3e321546bc 877 SUPERFAMILY SSF101353 246 438 2.09E-70 T 11-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 AFK25_10685 25b243a2aa60041e2d2c0a3e321546bc 877 Gene3D G3DSA:2.40.30.130 468 551 2.7E-10 T 11-10-2018 AFK25_10685 25b243a2aa60041e2d2c0a3e321546bc 877 SUPERFAMILY SSF50447 455 554 5.65E-18 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFK25_10685 25b243a2aa60041e2d2c0a3e321546bc 877 Pfam PF01411 tRNA synthetases class II (A) 8 556 2.5E-215 T 11-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 AFK25_10685 25b243a2aa60041e2d2c0a3e321546bc 877 Gene3D G3DSA:3.30.930.10 3 242 1.4E-95 T 11-10-2018 AFK25_10685 25b243a2aa60041e2d2c0a3e321546bc 877 Pfam PF02272 DHHA1 domain 735 874 2.1E-32 T 11-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 AFK25_10685 25b243a2aa60041e2d2c0a3e321546bc 877 Gene3D G3DSA:3.30.980.10 564 699 1.4E-52 T 11-10-2018 AFK25_10685 25b243a2aa60041e2d2c0a3e321546bc 877 Hamap MF_00036_B Alanine--tRNA ligase [alaS]. 1 877 188.116 T 11-10-2018 IPR023033 Alanine-tRNA ligase, eukaryota/bacteria GO:0004813 KEGG: 00970+6.1.1.7 AFK25_00320 4d42ba904ae0043fbe4a8319b93d40f9 97 ProDom PD067726 YABP B.SUBTILIS PRECURSOR UNCHARACTERIZED BH0074 SIGNAL CPE2477 PROTEIN 13 97 7.0E-37 T 11-10-2018 IPR012504 Sporulation protein YabP AFK25_00320 4d42ba904ae0043fbe4a8319b93d40f9 97 TIGRFAM TIGR02892 spore_yabP: sporulation protein YabP 14 97 1.9E-34 T 11-10-2018 IPR012504 Sporulation protein YabP AFK25_00320 4d42ba904ae0043fbe4a8319b93d40f9 97 Gene3D G3DSA:2.60.40.2000 22 79 6.6E-24 T 11-10-2018 IPR038705 YabP superfamily AFK25_00320 4d42ba904ae0043fbe4a8319b93d40f9 97 Pfam PF07873 YabP family 14 79 4.3E-21 T 11-10-2018 IPR022476 Sporulation protein YabP/YqfC AFK25_00320 4d42ba904ae0043fbe4a8319b93d40f9 97 PIRSF PIRSF011576 2 97 1.2E-50 T 11-10-2018 IPR012504 Sporulation protein YabP AFK25_09635 9af5c2af724a1bb366914ec7423a90f4 371 TIGRFAM TIGR04053 sam_11: radical SAM protein, BA_1875 family 3 360 2.1E-159 T 11-10-2018 IPR027634 Radical SAM protein, BA_1875 family AFK25_09635 9af5c2af724a1bb366914ec7423a90f4 371 SUPERFAMILY SSF102114 6 337 1.96E-67 T 11-10-2018 AFK25_09635 9af5c2af724a1bb366914ec7423a90f4 371 PIRSF PIRSF037420 1 370 1.5E-101 T 11-10-2018 IPR017200 Coenzyme PQQ synthesis protein E AFK25_09635 9af5c2af724a1bb366914ec7423a90f4 371 SMART SM00729 9 211 0.0033 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFK25_09635 9af5c2af724a1bb366914ec7423a90f4 371 Gene3D G3DSA:3.20.20.70 3 308 9.9E-47 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_09635 9af5c2af724a1bb366914ec7423a90f4 371 Pfam PF04055 Radical SAM superfamily 15 167 1.3E-18 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFK25_09635 9af5c2af724a1bb366914ec7423a90f4 371 Pfam PF13353 4Fe-4S single cluster domain 12 84 4.8E-6 T 11-10-2018 AFK25_08900 b9ce42bc73b939de3633caf4e3f8530c 336 SUPERFAMILY SSF52418 73 331 9.16E-83 T 11-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFK25_08900 b9ce42bc73b939de3633caf4e3f8530c 336 SUPERFAMILY SSF47648 3 68 2.09E-19 T 11-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFK25_08900 b9ce42bc73b939de3633caf4e3f8530c 336 Pfam PF00591 Glycosyl transferase family, a/b domain 73 324 1.0E-87 T 11-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFK25_08900 b9ce42bc73b939de3633caf4e3f8530c 336 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 7 330 6.0E-117 T 11-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 AFK25_08900 b9ce42bc73b939de3633caf4e3f8530c 336 Gene3D G3DSA:3.40.1030.10 70 334 1.8E-92 T 11-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFK25_08900 b9ce42bc73b939de3633caf4e3f8530c 336 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 4 333 36.013 T 11-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 AFK25_08900 b9ce42bc73b939de3633caf4e3f8530c 336 Gene3D G3DSA:1.20.970.10 4 68 2.6E-23 T 11-10-2018 AFK25_08900 b9ce42bc73b939de3633caf4e3f8530c 336 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 64 2.3E-19 T 11-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFK25_12190 bc771b03013c258c07c1a12226c91a99 74 Pfam PF01809 Haemolytic domain 2 68 2.5E-32 T 11-10-2018 IPR002696 Putative membrane protein insertion efficiency factor AFK25_12190 bc771b03013c258c07c1a12226c91a99 74 Hamap MF_00386 Putative membrane protein insertion efficiency factor [yidD]. 1 69 26.003 T 11-10-2018 IPR002696 Putative membrane protein insertion efficiency factor AFK25_12190 bc771b03013c258c07c1a12226c91a99 74 TIGRFAM TIGR00278 TIGR00278: putative membrane protein insertion efficiency factor 5 74 7.3E-34 T 11-10-2018 IPR002696 Putative membrane protein insertion efficiency factor AFK25_12190 bc771b03013c258c07c1a12226c91a99 74 ProDom PD004225 UPF0161 ALPHA-HEMOLYSIN YIDD UNCHARACTERIZED CYTOSOLIC PRECURSOR SIGNAL YTJA RNPA SIMILAR 16 68 1.0E-22 T 11-10-2018 IPR002696 Putative membrane protein insertion efficiency factor AFK25_12190 bc771b03013c258c07c1a12226c91a99 74 SMART SM01234 1 68 1.2E-48 T 11-10-2018 IPR002696 Putative membrane protein insertion efficiency factor AFK25_11615 6741194020454265b343c311067edc94 372 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 5 371 2.1E-167 T 11-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 AFK25_11615 6741194020454265b343c311067edc94 372 PIRSF PIRSF001369 1 372 1.4E-159 T 11-10-2018 IPR024176 Citrate synthase, bacterial-type AFK25_11615 6741194020454265b343c311067edc94 372 ProSitePatterns PS00480 Citrate synthase signature. 254 266 - T 11-10-2018 IPR019810 Citrate synthase active site GO:0006099|GO:0046912 Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AFK25_11615 6741194020454265b343c311067edc94 372 Gene3D G3DSA:1.10.580.10 24 344 9.8E-131 T 11-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AFK25_11615 6741194020454265b343c311067edc94 372 PRINTS PR00143 Citrate synthase signature 304 320 1.0E-43 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 AFK25_11615 6741194020454265b343c311067edc94 372 PRINTS PR00143 Citrate synthase signature 324 338 1.0E-43 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 AFK25_11615 6741194020454265b343c311067edc94 372 PRINTS PR00143 Citrate synthase signature 123 136 1.0E-43 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 AFK25_11615 6741194020454265b343c311067edc94 372 PRINTS PR00143 Citrate synthase signature 194 222 1.0E-43 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 AFK25_11615 6741194020454265b343c311067edc94 372 PRINTS PR00143 Citrate synthase signature 247 267 1.0E-43 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 AFK25_11615 6741194020454265b343c311067edc94 372 PRINTS PR00143 Citrate synthase signature 172 187 1.0E-43 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 AFK25_11615 6741194020454265b343c311067edc94 372 Gene3D G3DSA:1.10.230.10 220 318 9.8E-131 T 11-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain AFK25_11615 6741194020454265b343c311067edc94 372 Pfam PF00285 Citrate synthase, C-terminal domain 6 354 1.6E-133 T 11-10-2018 IPR002020 Citrate synthase GO:0046912 AFK25_11615 6741194020454265b343c311067edc94 372 SUPERFAMILY SSF48256 2 371 2.22E-139 T 11-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 AFK25_11950 318f866992c426809a0b45c424b8aba9 98 Pfam PF03413 Peptidase propeptide and YPEB domain 29 94 2.0E-8 T 11-10-2018 IPR025711 PepSY domain AFK25_03120 55502fbd6b59910798af8397dcbdca42 648 Gene3D G3DSA:3.30.70.270 212 391 7.6E-50 T 11-10-2018 AFK25_03120 55502fbd6b59910798af8397dcbdca42 648 Pfam PF00990 Diguanylate cyclase, GGDEF domain 217 373 3.4E-40 T 11-10-2018 IPR000160 GGDEF domain AFK25_03120 55502fbd6b59910798af8397dcbdca42 648 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 92 212 4.0E-28 T 11-10-2018 IPR000014 PAS domain AFK25_03120 55502fbd6b59910798af8397dcbdca42 648 Pfam PF00563 EAL domain 395 629 5.7E-78 T 11-10-2018 IPR001633 EAL domain AFK25_03120 55502fbd6b59910798af8397dcbdca42 648 SMART SM00091 94 160 4.9E-12 T 11-10-2018 IPR000014 PAS domain AFK25_03120 55502fbd6b59910798af8397dcbdca42 648 Gene3D G3DSA:3.20.20.450 392 642 2.7E-104 T 11-10-2018 IPR035919 EAL domain superfamily AFK25_03120 55502fbd6b59910798af8397dcbdca42 648 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 215 377 2.6E-35 T 11-10-2018 IPR000160 GGDEF domain AFK25_03120 55502fbd6b59910798af8397dcbdca42 648 SMART SM00052 388 634 6.5E-122 T 11-10-2018 IPR001633 EAL domain AFK25_03120 55502fbd6b59910798af8397dcbdca42 648 SUPERFAMILY SSF141868 393 641 9.68E-94 T 11-10-2018 IPR035919 EAL domain superfamily AFK25_03120 55502fbd6b59910798af8397dcbdca42 648 Pfam PF08448 PAS fold 100 208 2.6E-13 T 11-10-2018 IPR013656 PAS fold-4 AFK25_03120 55502fbd6b59910798af8397dcbdca42 648 SUPERFAMILY SSF55785 84 204 5.06E-25 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_03120 55502fbd6b59910798af8397dcbdca42 648 SUPERFAMILY SSF55073 223 378 1.02E-42 T 11-10-2018 IPR029787 Nucleotide cyclase AFK25_03120 55502fbd6b59910798af8397dcbdca42 648 Gene3D G3DSA:3.30.450.20 81 211 2.4E-26 T 11-10-2018 AFK25_03120 55502fbd6b59910798af8397dcbdca42 648 SMART SM00267 206 378 5.9E-47 T 11-10-2018 IPR000160 GGDEF domain AFK25_11100 4478d9e1d7e7d3313870a8298a70cb6a 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 122 136 5.7E-61 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFK25_11100 4478d9e1d7e7d3313870a8298a70cb6a 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 242 258 5.7E-61 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFK25_11100 4478d9e1d7e7d3313870a8298a70cb6a 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 190 209 5.7E-61 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFK25_11100 4478d9e1d7e7d3313870a8298a70cb6a 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 297 316 5.7E-61 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFK25_11100 4478d9e1d7e7d3313870a8298a70cb6a 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 152 171 5.7E-61 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFK25_11100 4478d9e1d7e7d3313870a8298a70cb6a 327 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 267 282 5.7E-61 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFK25_11100 4478d9e1d7e7d3313870a8298a70cb6a 327 Pfam PF00490 Delta-aminolevulinic acid dehydratase 7 322 3.9E-156 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFK25_11100 4478d9e1d7e7d3313870a8298a70cb6a 327 SUPERFAMILY SSF51569 4 325 4.4E-148 T 11-10-2018 AFK25_11100 4478d9e1d7e7d3313870a8298a70cb6a 327 PIRSF PIRSF001415 1 326 1.6E-159 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFK25_11100 4478d9e1d7e7d3313870a8298a70cb6a 327 SMART SM01004 4 323 9.7E-248 T 11-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFK25_11100 4478d9e1d7e7d3313870a8298a70cb6a 327 Gene3D G3DSA:3.20.20.70 1 327 3.8E-155 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_11100 4478d9e1d7e7d3313870a8298a70cb6a 327 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 242 254 - T 11-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AFK25_11150 768fb92101a86cf27729fd2fec098596 428 SUPERFAMILY SSF54534 89 243 4.91E-41 T 11-10-2018 AFK25_11150 768fb92101a86cf27729fd2fec098596 428 Pfam PF05697 Bacterial trigger factor protein (TF) 1 145 2.8E-45 T 11-10-2018 IPR008881 Trigger factor, ribosome-binding, bacterial GO:0006457|GO:0015031 AFK25_11150 768fb92101a86cf27729fd2fec098596 428 SUPERFAMILY SSF102735 1 129 1.7E-40 T 11-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 AFK25_11150 768fb92101a86cf27729fd2fec098596 428 SUPERFAMILY SSF109998 250 427 5.36E-45 T 11-10-2018 IPR027304 Trigger factor/SurA domain superfamily AFK25_11150 768fb92101a86cf27729fd2fec098596 428 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 160 239 9.4E-17 T 11-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain AFK25_11150 768fb92101a86cf27729fd2fec098596 428 Gene3D G3DSA:1.10.3120.10 117 426 6.5E-99 T 11-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 AFK25_11150 768fb92101a86cf27729fd2fec098596 428 Hamap MF_00303 Trigger factor [tig]. 1 427 24.813 T 11-10-2018 IPR005215 Trigger factor GO:0015031 AFK25_11150 768fb92101a86cf27729fd2fec098596 428 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 264 422 8.8E-47 T 11-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 AFK25_11150 768fb92101a86cf27729fd2fec098596 428 Gene3D G3DSA:3.30.70.1050 1 116 8.4E-33 T 11-10-2018 IPR036611 Trigger factor ribosome-binding domain superfamily GO:0006457|GO:0015031 AFK25_11150 768fb92101a86cf27729fd2fec098596 428 PIRSF PIRSF003095 1 428 6.8E-140 T 11-10-2018 IPR005215 Trigger factor GO:0015031 AFK25_11150 768fb92101a86cf27729fd2fec098596 428 TIGRFAM TIGR00115 tig: trigger factor 12 421 1.2E-146 T 11-10-2018 IPR005215 Trigger factor GO:0015031 AFK25_11150 768fb92101a86cf27729fd2fec098596 428 Gene3D G3DSA:3.10.50.40 151 248 6.5E-99 T 11-10-2018 AFK25_05145 b11b6fa4dc301b5adf74fec6607ce9f1 401 Pfam PF05636 HIGH Nucleotidyl Transferase 1 383 5.7E-143 T 11-10-2018 IPR008513 Uncharacterised protein family UPF0348 AFK25_05145 b11b6fa4dc301b5adf74fec6607ce9f1 401 Gene3D G3DSA:3.40.50.620 1 238 7.9E-40 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_05145 b11b6fa4dc301b5adf74fec6607ce9f1 401 SUPERFAMILY SSF52374 10 234 1.41E-21 T 11-10-2018 AFK25_05145 b11b6fa4dc301b5adf74fec6607ce9f1 401 Hamap MF_01539 UPF0348 protein . 2 401 40.219 T 11-10-2018 IPR008513 Uncharacterised protein family UPF0348 AFK25_10805 df68e2f0972a52fe79d1a53f6c1fdc5f 215 Gene3D G3DSA:3.30.240.20 80 154 2.3E-26 T 11-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily AFK25_10805 df68e2f0972a52fe79d1a53f6c1fdc5f 215 Pfam PF04239 Protein of unknown function (DUF421) 87 193 2.9E-37 T 11-10-2018 IPR007353 Protein of unknown function DUF421 AFK25_10805 df68e2f0972a52fe79d1a53f6c1fdc5f 215 Gene3D G3DSA:3.30.240.20 157 215 2.0E-16 T 11-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily AFK25_14460 e0c9f1a162189c1465068285542281df 539 Pfam PF13408 Recombinase zinc beta ribbon domain 294 359 2.2E-12 T 11-10-2018 IPR025827 Recombinase zinc beta ribbon domain AFK25_14460 e0c9f1a162189c1465068285542281df 539 Pfam PF00239 Resolvase, N terminal domain 4 153 1.3E-40 T 11-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFK25_14460 e0c9f1a162189c1465068285542281df 539 Pfam PF07508 Recombinase 178 281 6.2E-28 T 11-10-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 AFK25_14460 e0c9f1a162189c1465068285542281df 539 SMART SM00857 4 153 3.1E-58 T 11-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFK25_14460 e0c9f1a162189c1465068285542281df 539 ProSitePatterns PS00397 Site-specific recombinases active site. 7 15 - T 11-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 AFK25_14460 e0c9f1a162189c1465068285542281df 539 SUPERFAMILY SSF53041 3 153 1.09E-36 T 11-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 AFK25_14460 e0c9f1a162189c1465068285542281df 539 Gene3D G3DSA:3.40.50.1390 2 136 3.8E-43 T 11-10-2018 AFK25_14460 e0c9f1a162189c1465068285542281df 539 Gene3D G3DSA:1.10.10.2600 137 282 8.5E-31 T 11-10-2018 IPR038109 DNA-binding recombinase domain superfamily AFK25_13845 295c8393760d72f1025b8c7e90eb5004 504 PIRSF PIRSF039088 1 503 2.2E-252 T 11-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13845 295c8393760d72f1025b8c7e90eb5004 504 SUPERFAMILY SSF47917 372 502 2.09E-46 T 11-10-2018 AFK25_13845 295c8393760d72f1025b8c7e90eb5004 504 TIGRFAM TIGR00962 atpA: ATP synthase F1, alpha subunit 3 501 1.5E-259 T 11-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13845 295c8393760d72f1025b8c7e90eb5004 504 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 355 364 - T 11-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFK25_13845 295c8393760d72f1025b8c7e90eb5004 504 Hamap MF_01346 ATP synthase subunit alpha [atpA]. 1 501 51.858 T 11-10-2018 IPR005294 ATP synthase, F1 complex, alpha subunit GO:0015986|GO:0045261|GO:0046933 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13845 295c8393760d72f1025b8c7e90eb5004 504 Pfam PF00306 ATP synthase alpha/beta chain, C terminal domain 371 496 1.3E-45 T 11-10-2018 IPR000793 ATP synthase, alpha subunit, C-terminal GO:0015986 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13845 295c8393760d72f1025b8c7e90eb5004 504 Gene3D G3DSA:1.20.150.20 372 501 7.5E-53 T 11-10-2018 IPR038376 ATP synthase, alpha subunit, C-terminal domain superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1268020|Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13845 295c8393760d72f1025b8c7e90eb5004 504 Gene3D G3DSA:2.40.30.20 1 93 5.1E-38 T 11-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFK25_13845 295c8393760d72f1025b8c7e90eb5004 504 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 25 92 4.9E-21 T 11-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFK25_13845 295c8393760d72f1025b8c7e90eb5004 504 Gene3D G3DSA:3.40.50.300 94 371 4.6E-129 T 11-10-2018 AFK25_13845 295c8393760d72f1025b8c7e90eb5004 504 SUPERFAMILY SSF52540 95 370 4.81E-99 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_13845 295c8393760d72f1025b8c7e90eb5004 504 SUPERFAMILY SSF50615 10 94 5.49E-31 T 11-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFK25_13845 295c8393760d72f1025b8c7e90eb5004 504 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 149 364 1.1E-73 T 11-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFK25_06885 2f7a3b14ded3710c0f4cd5592db04174 667 Gene3D G3DSA:3.40.50.970 332 538 8.1E-82 T 11-10-2018 AFK25_06885 2f7a3b14ded3710c0f4cd5592db04174 667 ProSitePatterns PS00801 Transketolase signature 1. 14 34 - T 11-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFK25_06885 2f7a3b14ded3710c0f4cd5592db04174 667 SUPERFAMILY SSF52518 342 527 2.73E-71 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold AFK25_06885 2f7a3b14ded3710c0f4cd5592db04174 667 Pfam PF02780 Transketolase, C-terminal domain 552 657 2.6E-9 T 11-10-2018 IPR033248 Transketolase, C-terminal domain AFK25_06885 2f7a3b14ded3710c0f4cd5592db04174 667 ProSitePatterns PS00802 Transketolase signature 2. 468 484 - T 11-10-2018 IPR020826 Transketolase binding site KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFK25_06885 2f7a3b14ded3710c0f4cd5592db04174 667 SMART SM00861 355 526 2.3E-71 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFK25_06885 2f7a3b14ded3710c0f4cd5592db04174 667 Gene3D G3DSA:3.40.50.920 540 667 1.1E-41 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFK25_06885 2f7a3b14ded3710c0f4cd5592db04174 667 Pfam PF00456 Transketolase, thiamine diphosphate binding domain 6 339 3.3E-156 T 11-10-2018 IPR005474 Transketolase, N-terminal KEGG: 00730+2.2.1.7|KEGG: 00900+2.2.1.7|MetaCyc: PWY-6891|MetaCyc: PWY-6892|MetaCyc: PWY-7560 AFK25_06885 2f7a3b14ded3710c0f4cd5592db04174 667 Gene3D G3DSA:3.40.50.970 4 331 5.6E-132 T 11-10-2018 AFK25_06885 2f7a3b14ded3710c0f4cd5592db04174 667 SUPERFAMILY SSF52518 4 326 1.81E-122 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold AFK25_06885 2f7a3b14ded3710c0f4cd5592db04174 667 SUPERFAMILY SSF52922 535 666 6.28E-41 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFK25_06885 2f7a3b14ded3710c0f4cd5592db04174 667 Pfam PF02779 Transketolase, pyrimidine binding domain 354 525 7.7E-46 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFK25_06885 2f7a3b14ded3710c0f4cd5592db04174 667 TIGRFAM TIGR00232 tktlase_bact: transketolase 9 666 0.0 T 11-10-2018 IPR005478 Transketolase, bacterial-like GO:0004802 KEGG: 00030+2.2.1.1|KEGG: 00710+2.2.1.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|MetaCyc: PWY-6901 AFK25_12060 90e6294e311793f12c254ed8c0a4c454 190 SUPERFAMILY SSF53335 6 186 7.99E-26 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_12060 90e6294e311793f12c254ed8c0a4c454 190 Pfam PF06962 Putative rRNA methylase 48 188 9.1E-52 T 11-10-2018 IPR010719 Putative rRNA methylase AFK25_12060 90e6294e311793f12c254ed8c0a4c454 190 Gene3D G3DSA:3.40.50.150 1 190 2.0E-71 T 11-10-2018 AFK25_11475 6460d06d04f6817474c432639fb5ee35 328 Gene3D G3DSA:3.40.50.720 2 262 7.8E-128 T 11-10-2018 AFK25_11475 6460d06d04f6817474c432639fb5ee35 328 SUPERFAMILY SSF51735 2 326 6.13E-103 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_11475 6460d06d04f6817474c432639fb5ee35 328 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 1 324 6.0E-132 T 11-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 AFK25_11475 6460d06d04f6817474c432639fb5ee35 328 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 250 2.8E-62 T 11-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFK25_11475 6460d06d04f6817474c432639fb5ee35 328 Gene3D G3DSA:3.90.25.10 183 318 7.8E-128 T 11-10-2018 AFK25_01685 e87220f01c9130a3d372bfff0a1786a2 238 SUPERFAMILY SSF52768 24 208 1.06E-18 T 11-10-2018 IPR023696 Ureohydrolase domain superfamily AFK25_01685 e87220f01c9130a3d372bfff0a1786a2 238 Pfam PF00491 Arginase family 26 208 4.2E-9 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 AFK25_01685 e87220f01c9130a3d372bfff0a1786a2 238 Gene3D G3DSA:3.40.800.10 6 230 2.6E-12 T 11-10-2018 AFK25_01685 e87220f01c9130a3d372bfff0a1786a2 238 PIRSF PIRSF036979 9 207 8.6E-10 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 AFK25_07165 bad9be0babd2da84ecaee08df356f5d9 163 Gene3D G3DSA:3.40.430.10 1 163 3.7E-62 T 11-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFK25_07165 bad9be0babd2da84ecaee08df356f5d9 163 PIRSF PIRSF000194 1 163 3.5E-62 T 11-10-2018 IPR012259 Dihydrofolate reductase GO:0004146|GO:0006545|GO:0046654|GO:0050661|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614 AFK25_07165 bad9be0babd2da84ecaee08df356f5d9 163 PRINTS PR00070 Dihydrofolate reductase signature 13 23 4.5E-16 T 11-10-2018 AFK25_07165 bad9be0babd2da84ecaee08df356f5d9 163 PRINTS PR00070 Dihydrofolate reductase signature 27 35 4.5E-16 T 11-10-2018 AFK25_07165 bad9be0babd2da84ecaee08df356f5d9 163 PRINTS PR00070 Dihydrofolate reductase signature 40 51 4.5E-16 T 11-10-2018 AFK25_07165 bad9be0babd2da84ecaee08df356f5d9 163 PRINTS PR00070 Dihydrofolate reductase signature 92 106 4.5E-16 T 11-10-2018 AFK25_07165 bad9be0babd2da84ecaee08df356f5d9 163 ProSitePatterns PS00075 Dihydrofolate reductase (DHFR) domain signature. 13 35 - T 11-10-2018 IPR017925 Dihydrofolate reductase conserved site GO:0004146|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-1474151|Reactome: R-HSA-196757|Reactome: R-HSA-539107 AFK25_07165 bad9be0babd2da84ecaee08df356f5d9 163 Pfam PF00186 Dihydrofolate reductase 2 160 2.0E-64 T 11-10-2018 IPR001796 Dihydrofolate reductase domain GO:0004146|GO:0046654|GO:0055114 KEGG: 00670+1.5.1.3|KEGG: 00790+1.5.1.3|MetaCyc: PWY-3841|MetaCyc: PWY-6614|Reactome: R-HSA-196757 AFK25_07165 bad9be0babd2da84ecaee08df356f5d9 163 SUPERFAMILY SSF53597 2 160 1.26E-61 T 11-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AFK25_00430 c090fd098e341c9ce9e60f35824d27c9 494 PIRSF PIRSF039101 2 494 6.2E-208 T 11-10-2018 IPR034762 Bacterial/eukaryotic lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFK25_00430 c090fd098e341c9ce9e60f35824d27c9 494 SUPERFAMILY SSF50249 5 146 6.21E-46 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_00430 c090fd098e341c9ce9e60f35824d27c9 494 SUPERFAMILY SSF55681 153 492 9.96E-127 T 11-10-2018 AFK25_00430 c090fd098e341c9ce9e60f35824d27c9 494 Gene3D G3DSA:3.30.930.10 147 491 2.1E-142 T 11-10-2018 AFK25_00430 c090fd098e341c9ce9e60f35824d27c9 494 Pfam PF00152 tRNA synthetases class II (D, K and N) 155 491 8.8E-84 T 11-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_00430 c090fd098e341c9ce9e60f35824d27c9 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 206 222 3.8E-40 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFK25_00430 c090fd098e341c9ce9e60f35824d27c9 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 376 392 3.8E-40 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFK25_00430 c090fd098e341c9ce9e60f35824d27c9 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 253 270 3.8E-40 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFK25_00430 c090fd098e341c9ce9e60f35824d27c9 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 190 200 3.8E-40 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFK25_00430 c090fd098e341c9ce9e60f35824d27c9 494 PRINTS PR00982 Lysyl-tRNA synthetase signature 235 248 3.8E-40 T 11-10-2018 IPR018149 Lysyl-tRNA synthetase, class II, C-terminal GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFK25_00430 c090fd098e341c9ce9e60f35824d27c9 494 Pfam PF01336 OB-fold nucleic acid binding domain 60 137 1.7E-15 T 11-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AFK25_00430 c090fd098e341c9ce9e60f35824d27c9 494 TIGRFAM TIGR00499 lysS_bact: lysine--tRNA ligase 5 493 2.1E-229 T 11-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFK25_00430 c090fd098e341c9ce9e60f35824d27c9 494 Hamap MF_00252 Lysine--tRNA ligase [lysS]. 12 494 46.832 T 11-10-2018 IPR002313 Lysine-tRNA ligase, class II GO:0004824|GO:0005524|GO:0006430 KEGG: 00970+6.1.1.6|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFK25_00430 c090fd098e341c9ce9e60f35824d27c9 494 Gene3D G3DSA:2.40.50.140 6 146 3.0E-48 T 11-10-2018 AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 SMART SM00533 271 580 4.7E-116 T 11-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 Gene3D G3DSA:3.40.1170.10 1 116 2.9E-48 T 11-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 Pfam PF01624 MutS domain I 4 114 1.4E-46 T 11-10-2018 IPR007695 DNA mismatch repair protein MutS-like, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 Gene3D G3DSA:3.40.50.300 558 854 3.1E-106 T 11-10-2018 AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 Gene3D G3DSA:1.10.1420.10 253 548 3.0E-103 T 11-10-2018 AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 SUPERFAMILY SSF48334 254 555 6.02E-92 T 11-10-2018 IPR036187 DNA mismatch repair protein MutS, core domain superfamily AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 Pfam PF00488 MutS domain V 601 787 1.7E-82 T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 Pfam PF05188 MutS domain II 124 187 1.8E-7 T 11-10-2018 IPR007860 DNA mismatch repair protein MutS, connector domain GO:0005524|GO:0006298|GO:0030983 AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 Pfam PF05192 MutS domain III 259 548 1.7E-44 T 11-10-2018 IPR007696 DNA mismatch repair protein MutS, core GO:0005524|GO:0006298|GO:0030983 AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 Gene3D G3DSA:3.30.420.110 123 248 2.1E-15 T 11-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 ProSitePatterns PS00486 DNA mismatch repair proteins mutS family signature. 678 694 - T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 TIGRFAM TIGR01070 mutS1: DNA mismatch repair protein MutS 3 851 0.0 T 11-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 SUPERFAMILY SSF53150 113 267 6.28E-31 T 11-10-2018 IPR036678 MutS, connector domain superfamily GO:0005524|GO:0006298|GO:0030983 AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 SMART SM00534 597 784 4.6E-118 T 11-10-2018 IPR000432 DNA mismatch repair protein MutS, C-terminal GO:0005524|GO:0006298|GO:0030983 AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. 3 845 25.723 T 11-10-2018 IPR005748 DNA mismatch repair protein MutS GO:0005524|GO:0006298|GO:0030983 AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 PIRSF PIRSF037677 157 835 1.1E-135 T 11-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 PIRSF PIRSF037677 1 162 6.7E-33 T 11-10-2018 IPR017261 DNA mismatch repair protein MutS/MSH GO:0006298|GO:0030983 AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 SUPERFAMILY SSF52540 556 787 6.16E-67 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 Gene3D G3DSA:1.10.1420.10 388 524 3.0E-103 T 11-10-2018 AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 SUPERFAMILY SSF55271 2 111 6.41E-43 T 11-10-2018 IPR016151 DNA mismatch repair protein MutS, N-terminal GO:0005524|GO:0006298|GO:0030983 Reactome: R-HSA-5632928 AFK25_06785 ce60f3168dc184002ee5baa474977cd6 854 Pfam PF05190 MutS family domain IV 416 507 1.4E-29 T 11-10-2018 IPR007861 DNA mismatch repair protein MutS, clamp GO:0005524|GO:0006298|GO:0030983 AFK25_02710 23f9921c0a09fe20411accc16f76468a 67 TIGRFAM TIGR01683 thiS: thiamine biosynthesis protein ThiS 3 67 3.6E-19 T 11-10-2018 IPR010035 ThiS, thiamine-biosynthesis AFK25_02710 23f9921c0a09fe20411accc16f76468a 67 Pfam PF02597 ThiS family 6 67 1.1E-11 T 11-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 AFK25_02710 23f9921c0a09fe20411accc16f76468a 67 Gene3D G3DSA:3.10.20.30 3 67 5.8E-20 T 11-10-2018 IPR012675 Beta-grasp domain superfamily AFK25_02710 23f9921c0a09fe20411accc16f76468a 67 SUPERFAMILY SSF54285 3 66 3.6E-17 T 11-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AFK25_00470 4e6c946e6927784238e34cd19b3f809e 464 Pfam PF13481 AAA domain 67 221 3.2E-20 T 11-10-2018 AFK25_00470 4e6c946e6927784238e34cd19b3f809e 464 Pfam PF13541 Subunit ChlI of Mg-chelatase 363 429 1.9E-10 T 11-10-2018 AFK25_00470 4e6c946e6927784238e34cd19b3f809e 464 Gene3D G3DSA:3.40.50.300 61 288 4.6E-47 T 11-10-2018 AFK25_00470 4e6c946e6927784238e34cd19b3f809e 464 PRINTS PR01874 DNA repair protein radA signature 81 109 4.5E-93 T 11-10-2018 AFK25_00470 4e6c946e6927784238e34cd19b3f809e 464 PRINTS PR01874 DNA repair protein radA signature 247 273 4.5E-93 T 11-10-2018 AFK25_00470 4e6c946e6927784238e34cd19b3f809e 464 PRINTS PR01874 DNA repair protein radA signature 10 34 4.5E-93 T 11-10-2018 AFK25_00470 4e6c946e6927784238e34cd19b3f809e 464 PRINTS PR01874 DNA repair protein radA signature 173 197 4.5E-93 T 11-10-2018 AFK25_00470 4e6c946e6927784238e34cd19b3f809e 464 PRINTS PR01874 DNA repair protein radA signature 123 140 4.5E-93 T 11-10-2018 AFK25_00470 4e6c946e6927784238e34cd19b3f809e 464 PRINTS PR01874 DNA repair protein radA signature 212 240 4.5E-93 T 11-10-2018 AFK25_00470 4e6c946e6927784238e34cd19b3f809e 464 PRINTS PR01874 DNA repair protein radA signature 321 344 4.5E-93 T 11-10-2018 AFK25_00470 4e6c946e6927784238e34cd19b3f809e 464 Hamap MF_01498 DNA repair protein RadA [radA]. 21 455 45.204 T 11-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 AFK25_00470 4e6c946e6927784238e34cd19b3f809e 464 SMART SM00382 89 243 8.3E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_00470 4e6c946e6927784238e34cd19b3f809e 464 SUPERFAMILY SSF52540 68 289 4.21E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_00470 4e6c946e6927784238e34cd19b3f809e 464 SUPERFAMILY SSF54211 254 456 2.62E-44 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFK25_00470 4e6c946e6927784238e34cd19b3f809e 464 TIGRFAM TIGR00416 sms: DNA repair protein RadA 1 451 5.2E-215 T 11-10-2018 IPR004504 DNA repair protein RadA GO:0003684|GO:0005524|GO:0006281 AFK25_00470 4e6c946e6927784238e34cd19b3f809e 464 Gene3D G3DSA:3.30.230.10 289 463 6.7E-22 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFK25_10555 91a95543bf0f466235dec34ab15b7bda 725 SUPERFAMILY SSF52540 231 535 6.6E-31 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_10555 91a95543bf0f466235dec34ab15b7bda 725 Gene3D G3DSA:3.40.50.300 414 561 4.5E-11 T 11-10-2018 AFK25_10555 91a95543bf0f466235dec34ab15b7bda 725 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 14 193 1.7E-18 T 11-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain AFK25_10555 91a95543bf0f466235dec34ab15b7bda 725 SMART SM00487 216 415 2.2E-7 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFK25_10555 91a95543bf0f466235dec34ab15b7bda 725 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 236 572 5.1E-75 T 11-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core AFK25_10555 91a95543bf0f466235dec34ab15b7bda 725 Pfam PF00271 Helicase conserved C-terminal domain 432 534 3.7E-8 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_10555 91a95543bf0f466235dec34ab15b7bda 725 Gene3D G3DSA:3.40.50.300 208 399 2.2E-11 T 11-10-2018 AFK25_10555 91a95543bf0f466235dec34ab15b7bda 725 Pfam PF00270 DEAD/DEAH box helicase 231 384 1.4E-8 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFK25_10555 91a95543bf0f466235dec34ab15b7bda 725 Gene3D G3DSA:1.10.3210.30 1 183 1.4E-13 T 11-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily AFK25_10555 91a95543bf0f466235dec34ab15b7bda 725 SMART SM00490 452 535 0.0026 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_13105 f46d255d73510f60089361981d76604c 108 Gene3D G3DSA:1.10.760.10 39 108 1.5E-30 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFK25_13105 f46d255d73510f60089361981d76604c 108 SUPERFAMILY SSF46626 1 106 2.54E-20 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFK25_13105 f46d255d73510f60089361981d76604c 108 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 37 104 3.6E-14 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_13105 f46d255d73510f60089361981d76604c 108 PIRSF PIRSF000025 1 108 6.6E-35 T 11-10-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 AFK25_03510 152d91b61164040f6df960d5bb30e981 604 TIGRFAM TIGR00181 pepF: oligoendopeptidase F 14 603 2.2E-220 T 11-10-2018 IPR004438 Peptidase M3B, oligoendopeptidase F GO:0004222|GO:0006508 AFK25_03510 152d91b61164040f6df960d5bb30e981 604 Gene3D G3DSA:1.20.140.70 31 186 1.7E-53 T 11-10-2018 AFK25_03510 152d91b61164040f6df960d5bb30e981 604 Pfam PF08439 Oligopeptidase F 121 190 4.1E-22 T 11-10-2018 IPR013647 Oligopeptidase F, N-terminal domain AFK25_03510 152d91b61164040f6df960d5bb30e981 604 Pfam PF01432 Peptidase family M3 212 591 2.1E-83 T 11-10-2018 IPR001567 Peptidase M3A/M3B catalytic domain GO:0004222|GO:0006508 AFK25_03510 152d91b61164040f6df960d5bb30e981 604 Gene3D G3DSA:1.10.287.830 188 234 1.3E-21 T 11-10-2018 AFK25_03510 152d91b61164040f6df960d5bb30e981 604 Gene3D G3DSA:1.10.1370.20 235 604 1.7E-146 T 11-10-2018 AFK25_03510 152d91b61164040f6df960d5bb30e981 604 SUPERFAMILY SSF55486 61 603 3.08E-140 T 11-10-2018 AFK25_14285 8d375ce69306270f88754b7e0f6f7220 221 Pfam PF13419 Haloacid dehalogenase-like hydrolase 5 186 2.2E-28 T 11-10-2018 AFK25_14285 8d375ce69306270f88754b7e0f6f7220 221 SUPERFAMILY SSF56784 1 206 5.02E-48 T 11-10-2018 IPR036412 HAD-like superfamily AFK25_14285 8d375ce69306270f88754b7e0f6f7220 221 TIGRFAM TIGR01990 bPGM: beta-phosphoglucomutase 2 188 1.3E-70 T 11-10-2018 IPR010972 Beta-phosphoglucomutase GO:0000287|GO:0005975|GO:0008801 KEGG: 00500+5.4.2.6|MetaCyc: PWY-2721|MetaCyc: PWY-2722|MetaCyc: PWY-7459 AFK25_14285 8d375ce69306270f88754b7e0f6f7220 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 149 169 3.7E-7 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFK25_14285 8d375ce69306270f88754b7e0f6f7220 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 2 13 3.7E-7 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFK25_14285 8d375ce69306270f88754b7e0f6f7220 221 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 131 147 3.7E-7 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFK25_14285 8d375ce69306270f88754b7e0f6f7220 221 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 45 187 3.9E-17 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFK25_14285 8d375ce69306270f88754b7e0f6f7220 221 Gene3D G3DSA:1.10.150.240 15 91 8.0E-62 T 11-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 AFK25_14285 8d375ce69306270f88754b7e0f6f7220 221 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 2 187 5.6E-58 T 11-10-2018 IPR010976 Beta-phosphoglucomutase hydrolase AFK25_14285 8d375ce69306270f88754b7e0f6f7220 221 Gene3D G3DSA:3.40.50.1000 3 193 8.0E-62 T 11-10-2018 IPR023214 HAD superfamily AFK25_02760 8201128bfdbbd847de07e49f59766267 370 Gene3D G3DSA:2.40.50.100 240 361 1.8E-37 T 11-10-2018 AFK25_02760 8201128bfdbbd847de07e49f59766267 370 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_02760 8201128bfdbbd847de07e49f59766267 370 SUPERFAMILY SSF50331 237 365 1.21E-30 T 11-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFK25_02760 8201128bfdbbd847de07e49f59766267 370 SUPERFAMILY SSF52540 4 243 1.5E-86 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_02760 8201128bfdbbd847de07e49f59766267 370 SMART SM00382 29 212 7.7E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_02760 8201128bfdbbd847de07e49f59766267 370 Gene3D G3DSA:3.40.50.300 1 239 3.5E-77 T 11-10-2018 AFK25_02760 8201128bfdbbd847de07e49f59766267 370 Pfam PF00005 ABC transporter 21 162 7.7E-29 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_02760 8201128bfdbbd847de07e49f59766267 370 Gene3D G3DSA:2.40.50.140 303 348 1.8E-37 T 11-10-2018 AFK25_02760 8201128bfdbbd847de07e49f59766267 370 Pfam PF08402 TOBE domain 281 356 2.0E-8 T 11-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 AFK25_05980 c6f69064cd937d86de75bf35e446e1b4 746 SMART SM00843 675 740 1.7E-41 T 11-10-2018 IPR018541 FtsK gamma domain AFK25_05980 c6f69064cd937d86de75bf35e446e1b4 746 Gene3D G3DSA:3.30.980.40 277 380 1.3E-39 T 11-10-2018 AFK25_05980 c6f69064cd937d86de75bf35e446e1b4 746 SUPERFAMILY SSF46785 677 741 3.26E-23 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_05980 c6f69064cd937d86de75bf35e446e1b4 746 SUPERFAMILY SSF52540 358 652 1.08E-48 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_05980 c6f69064cd937d86de75bf35e446e1b4 746 Gene3D G3DSA:3.40.50.300 382 667 2.6E-113 T 11-10-2018 AFK25_05980 c6f69064cd937d86de75bf35e446e1b4 746 Pfam PF01580 FtsK/SpoIIIE family 385 581 4.2E-67 T 11-10-2018 IPR002543 FtsK domain GO:0000166|GO:0003677|GO:0005524 AFK25_05980 c6f69064cd937d86de75bf35e446e1b4 746 Pfam PF09397 Ftsk gamma domain 678 737 6.8E-31 T 11-10-2018 IPR018541 FtsK gamma domain AFK25_05980 c6f69064cd937d86de75bf35e446e1b4 746 SMART SM00382 420 602 1.4E-5 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_05980 c6f69064cd937d86de75bf35e446e1b4 746 Gene3D G3DSA:1.10.10.10 679 741 2.6E-28 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_03030 19ef2ab24859d74b0e46a958e12c4d1c 1157 Gene3D G3DSA:3.40.50.300 4 140 1.3E-34 T 11-10-2018 AFK25_03030 19ef2ab24859d74b0e46a958e12c4d1c 1157 Pfam PF12705 PD-(D/E)XK nuclease superfamily 791 1133 5.0E-63 T 11-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type AFK25_03030 19ef2ab24859d74b0e46a958e12c4d1c 1157 Hamap MF_01452 ATP-dependent helicase/deoxyribonuclease subunit B [addB]. 4 1157 64.765 T 11-10-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 AFK25_03030 19ef2ab24859d74b0e46a958e12c4d1c 1157 Pfam PF13361 UvrD-like helicase C-terminal domain 308 670 2.4E-8 T 11-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFK25_03030 19ef2ab24859d74b0e46a958e12c4d1c 1157 Gene3D G3DSA:3.40.50.300 282 405 4.0E-32 T 11-10-2018 AFK25_03030 19ef2ab24859d74b0e46a958e12c4d1c 1157 Gene3D G3DSA:3.40.50.300 560 699 5.6E-39 T 11-10-2018 AFK25_03030 19ef2ab24859d74b0e46a958e12c4d1c 1157 SUPERFAMILY SSF52540 308 707 4.4E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_03030 19ef2ab24859d74b0e46a958e12c4d1c 1157 TIGRFAM TIGR02773 addB_Gpos: helicase-exonuclease AddAB, AddB subunit 4 1149 0.0 T 11-10-2018 IPR014140 DNA helicase subunit AddB GO:0000724|GO:0016788 AFK25_10675 3b2a9b78a68a343056472247e8beb631 140 SMART SM00732 1 103 1.8E-40 T 11-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 AFK25_10675 3b2a9b78a68a343056472247e8beb631 140 SUPERFAMILY SSF53098 1 136 4.25E-46 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_10675 3b2a9b78a68a343056472247e8beb631 140 Hamap MF_00651 Putative pre-16S rRNA nuclease [yqgF]. 1 138 28.426 T 11-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 AFK25_10675 3b2a9b78a68a343056472247e8beb631 140 Gene3D G3DSA:3.30.420.140 1 140 2.1E-53 T 11-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 AFK25_10675 3b2a9b78a68a343056472247e8beb631 140 Pfam PF03652 Holliday junction resolvase 1 135 2.3E-46 T 11-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 AFK25_10675 3b2a9b78a68a343056472247e8beb631 140 TIGRFAM TIGR00250 RNAse_H_YqgF: putative transcription antitermination factor YqgF 4 135 3.7E-54 T 11-10-2018 IPR005227 Putative pre-16S rRNA nuclease GO:0006364 AFK25_11435 1cbccdd95036b5cd4b6deac7f18c3ae1 578 SUPERFAMILY SSF55874 424 575 1.03E-19 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_11435 1cbccdd95036b5cd4b6deac7f18c3ae1 578 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 468 576 1.2E-12 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_11435 1cbccdd95036b5cd4b6deac7f18c3ae1 578 Pfam PF06580 Histidine kinase 368 449 6.4E-26 T 11-10-2018 IPR010559 Signal transduction histidine kinase, internal region GO:0000155|GO:0000160|GO:0016021 AFK25_11435 1cbccdd95036b5cd4b6deac7f18c3ae1 578 Pfam PF02743 Cache domain 47 267 4.1E-13 T 11-10-2018 IPR033479 Double Cache domain 1 AFK25_11435 1cbccdd95036b5cd4b6deac7f18c3ae1 578 Gene3D G3DSA:3.30.565.10 435 577 4.3E-18 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_11435 1cbccdd95036b5cd4b6deac7f18c3ae1 578 SMART SM00387 460 578 3.3E-8 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_11435 1cbccdd95036b5cd4b6deac7f18c3ae1 578 PRINTS PR00344 Bacterial sensor protein C-terminal signature 503 517 6.1E-7 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_11435 1cbccdd95036b5cd4b6deac7f18c3ae1 578 PRINTS PR00344 Bacterial sensor protein C-terminal signature 562 575 6.1E-7 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_11435 1cbccdd95036b5cd4b6deac7f18c3ae1 578 PRINTS PR00344 Bacterial sensor protein C-terminal signature 535 553 6.1E-7 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04630 076a8d6cd76a9fd1fd8b489ebf214468 340 Pfam PF01476 LysM domain 169 213 3.1E-11 T 11-10-2018 IPR018392 LysM domain AFK25_04630 076a8d6cd76a9fd1fd8b489ebf214468 340 Pfam PF01476 LysM domain 92 136 6.9E-14 T 11-10-2018 IPR018392 LysM domain AFK25_04630 076a8d6cd76a9fd1fd8b489ebf214468 340 Pfam PF01476 LysM domain 26 68 1.5E-14 T 11-10-2018 IPR018392 LysM domain AFK25_04630 076a8d6cd76a9fd1fd8b489ebf214468 340 SUPERFAMILY SSF54106 168 213 4.32E-10 T 11-10-2018 AFK25_04630 076a8d6cd76a9fd1fd8b489ebf214468 340 Pfam PF00877 NlpC/P60 family 232 338 2.3E-21 T 11-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain AFK25_04630 076a8d6cd76a9fd1fd8b489ebf214468 340 SUPERFAMILY SSF54001 211 339 2.68E-31 T 11-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFK25_04630 076a8d6cd76a9fd1fd8b489ebf214468 340 SUPERFAMILY SSF54106 25 68 5.23E-12 T 11-10-2018 AFK25_04630 076a8d6cd76a9fd1fd8b489ebf214468 340 SUPERFAMILY SSF54106 90 136 1.11E-11 T 11-10-2018 AFK25_04630 076a8d6cd76a9fd1fd8b489ebf214468 340 Gene3D G3DSA:3.10.350.10 155 220 1.6E-18 T 11-10-2018 IPR036779 LysM domain superfamily AFK25_04630 076a8d6cd76a9fd1fd8b489ebf214468 340 Gene3D G3DSA:3.10.350.10 77 152 5.4E-20 T 11-10-2018 IPR036779 LysM domain superfamily AFK25_04630 076a8d6cd76a9fd1fd8b489ebf214468 340 Gene3D G3DSA:3.90.1720.10 221 340 2.3E-31 T 11-10-2018 AFK25_04630 076a8d6cd76a9fd1fd8b489ebf214468 340 SMART SM00257 91 136 1.1E-15 T 11-10-2018 IPR018392 LysM domain AFK25_04630 076a8d6cd76a9fd1fd8b489ebf214468 340 SMART SM00257 168 213 4.7E-13 T 11-10-2018 IPR018392 LysM domain AFK25_04630 076a8d6cd76a9fd1fd8b489ebf214468 340 SMART SM00257 25 68 1.2E-16 T 11-10-2018 IPR018392 LysM domain AFK25_04630 076a8d6cd76a9fd1fd8b489ebf214468 340 Gene3D G3DSA:3.10.350.10 22 74 9.6E-19 T 11-10-2018 IPR036779 LysM domain superfamily AFK25_01070 f85972f9ceb37a66dbadcb0c48bfa294 354 Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. 3 341 42.69 T 11-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFK25_01070 f85972f9ceb37a66dbadcb0c48bfa294 354 ProSitePatterns PS00843 D-alanine--D-alanine ligase signature 1. 95 106 - T 11-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFK25_01070 f85972f9ceb37a66dbadcb0c48bfa294 354 TIGRFAM TIGR01205 D_ala_D_alaTIGR: D-alanine--D-alanine ligase 5 340 2.4E-120 T 11-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFK25_01070 f85972f9ceb37a66dbadcb0c48bfa294 354 ProSitePatterns PS00844 D-alanine--D-alanine ligase signature 2. 283 311 - T 11-10-2018 IPR000291 D-alanine--D-alanine ligase/VANA/B/C, conserved site KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFK25_01070 f85972f9ceb37a66dbadcb0c48bfa294 354 PIRSF PIRSF039102 1 349 1.5E-122 T 11-10-2018 IPR005905 D-alanine--D-alanine ligase GO:0005737|GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFK25_01070 f85972f9ceb37a66dbadcb0c48bfa294 354 Gene3D G3DSA:3.40.50.20 1 116 5.4E-39 T 11-10-2018 AFK25_01070 f85972f9ceb37a66dbadcb0c48bfa294 354 SUPERFAMILY SSF52440 1 127 3.74E-36 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFK25_01070 f85972f9ceb37a66dbadcb0c48bfa294 354 Pfam PF01820 D-ala D-ala ligase N-terminus 5 117 3.6E-32 T 11-10-2018 IPR011127 D-alanine--D-alanine ligase, N-terminal domain KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFK25_01070 f85972f9ceb37a66dbadcb0c48bfa294 354 SUPERFAMILY SSF56059 128 344 6.36E-65 T 11-10-2018 AFK25_01070 f85972f9ceb37a66dbadcb0c48bfa294 354 Gene3D G3DSA:3.30.470.20 216 354 1.2E-54 T 11-10-2018 AFK25_01070 f85972f9ceb37a66dbadcb0c48bfa294 354 Pfam PF07478 D-ala D-ala ligase C-terminus 135 338 2.3E-83 T 11-10-2018 IPR011095 D-alanine--D-alanine ligase, C-terminal GO:0008716 KEGG: 00473+6.3.2.4|KEGG: 00550+6.3.2.4|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFK25_01070 f85972f9ceb37a66dbadcb0c48bfa294 354 Gene3D G3DSA:3.30.1490.20 143 215 2.7E-30 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFK25_12490 02e36a551050e9927b21e2bbee73376e 386 Gene3D G3DSA:3.40.50.1970 1 183 3.4E-56 T 11-10-2018 AFK25_12490 02e36a551050e9927b21e2bbee73376e 386 SUPERFAMILY SSF56796 1 384 1.05E-116 T 11-10-2018 AFK25_12490 02e36a551050e9927b21e2bbee73376e 386 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 263 283 - T 11-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 AFK25_12490 02e36a551050e9927b21e2bbee73376e 386 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 172 200 - T 11-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 AFK25_12490 02e36a551050e9927b21e2bbee73376e 386 Pfam PF00465 Iron-containing alcohol dehydrogenase 9 369 2.4E-101 T 11-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 AFK25_12490 02e36a551050e9927b21e2bbee73376e 386 Gene3D G3DSA:1.20.1090.10 184 385 1.5E-43 T 11-10-2018 AFK25_05655 ca08daab2a59ceb2efbda419b32aa742 145 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 11-10-2018 IPR019776 Flagellar basal body rod protein, conserved site AFK25_05655 ca08daab2a59ceb2efbda419b32aa742 145 Pfam PF00460 Flagella basal body rod protein 5 35 2.3E-10 T 11-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 AFK25_05655 ca08daab2a59ceb2efbda419b32aa742 145 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 95 142 1.9E-11 T 11-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain AFK25_05655 ca08daab2a59ceb2efbda419b32aa742 145 TIGRFAM TIGR01395 FlgC: flagellar basal-body rod protein FlgC 2 145 3.2E-54 T 11-10-2018 IPR006299 Flagellar basal-body rod protein FlgC GO:0030694|GO:0071973 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 Gene3D G3DSA:3.40.50.670 405 640 2.2E-112 T 11-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 Pfam PF00204 DNA gyrase B 227 396 2.9E-65 T 11-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 Gene3D G3DSA:3.30.565.10 9 225 4.2E-94 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 ProSitePatterns PS00177 DNA topoisomerase II signature. 428 436 - T 11-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 569 629 2.7E-31 T 11-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 Gene3D G3DSA:3.30.230.10 226 404 1.7E-74 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 SUPERFAMILY SSF54211 227 397 8.16E-63 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 38 179 6.8E-22 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 SUPERFAMILY SSF55874 11 223 1.7E-76 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 TIGRFAM TIGR01059 gyrB: DNA gyrase, B subunit 11 640 0.0 T 11-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 SUPERFAMILY SSF56719 400 632 5.75E-93 T 11-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 PRINTS PR00418 DNA topoisomerase II family signature 40 55 2.7E-74 T 11-10-2018 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 PRINTS PR00418 DNA topoisomerase II family signature 426 440 2.7E-74 T 11-10-2018 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 PRINTS PR00418 DNA topoisomerase II family signature 118 132 2.7E-74 T 11-10-2018 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 PRINTS PR00418 DNA topoisomerase II family signature 510 527 2.7E-74 T 11-10-2018 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 PRINTS PR00418 DNA topoisomerase II family signature 274 287 2.7E-74 T 11-10-2018 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 PRINTS PR00418 DNA topoisomerase II family signature 572 588 2.7E-74 T 11-10-2018 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 PRINTS PR00418 DNA topoisomerase II family signature 75 88 2.7E-74 T 11-10-2018 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 PRINTS PR00418 DNA topoisomerase II family signature 492 508 2.7E-74 T 11-10-2018 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 PRINTS PR00418 DNA topoisomerase II family signature 530 542 2.7E-74 T 11-10-2018 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 SMART SM00433 40 633 0.0 T 11-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 Hamap MF_01898 DNA gyrase subunit B [gyrB]. 8 640 98.783 T 11-10-2018 IPR011557 DNA gyrase, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 SMART SM00387 36 180 1.6E-28 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 PRINTS PR01159 DNA gyrase subunit B signature 11 21 1.8E-80 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 PRINTS PR01159 DNA gyrase subunit B signature 593 605 1.8E-80 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 PRINTS PR01159 DNA gyrase subunit B signature 609 625 1.8E-80 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 PRINTS PR01159 DNA gyrase subunit B signature 186 201 1.8E-80 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 PRINTS PR01159 DNA gyrase subunit B signature 366 380 1.8E-80 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 PRINTS PR01159 DNA gyrase subunit B signature 476 485 1.8E-80 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 PRINTS PR01159 DNA gyrase subunit B signature 226 248 1.8E-80 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 PRINTS PR01159 DNA gyrase subunit B signature 318 334 1.8E-80 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 PRINTS PR01159 DNA gyrase subunit B signature 380 400 1.8E-80 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 PRINTS PR01159 DNA gyrase subunit B signature 201 214 1.8E-80 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_00025 3821d39acd6517fdc7da9fcaa6ae03a5 640 Pfam PF01751 Toprim domain 425 536 1.1E-18 T 11-10-2018 IPR006171 TOPRIM domain AFK25_10165 29be2824bee59bc383e00be5dcb88e5d 701 Pfam PF00905 Penicillin binding protein transpeptidase domain 338 671 4.7E-68 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFK25_10165 29be2824bee59bc383e00be5dcb88e5d 701 Gene3D G3DSA:3.40.710.10 305 655 1.6E-245 T 11-10-2018 AFK25_10165 29be2824bee59bc383e00be5dcb88e5d 701 Gene3D G3DSA:3.90.1310.30 53 562 1.6E-245 T 11-10-2018 AFK25_10165 29be2824bee59bc383e00be5dcb88e5d 701 Pfam PF03717 Penicillin-binding Protein dimerisation domain 50 291 1.5E-40 T 11-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 AFK25_10165 29be2824bee59bc383e00be5dcb88e5d 701 Gene3D G3DSA:1.10.10.1230 78 180 1.6E-245 T 11-10-2018 AFK25_10165 29be2824bee59bc383e00be5dcb88e5d 701 SUPERFAMILY SSF56601 257 680 4.27E-71 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFK25_10165 29be2824bee59bc383e00be5dcb88e5d 701 SUPERFAMILY SSF56519 47 305 9.68E-37 T 11-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 AFK25_05240 b98d7ae6e2e9bd76fee829a2dde6ac2c 230 Pfam PF05949 Bacterial protein of unknown function (DUF881) 93 226 7.9E-36 T 11-10-2018 IPR010273 Protein of unknown function DUF881 AFK25_05240 b98d7ae6e2e9bd76fee829a2dde6ac2c 230 Gene3D G3DSA:3.30.70.1880 92 230 2.9E-34 T 11-10-2018 AFK25_12480 08bc9f2c70931103e2f8f504be17e684 134 Gene3D G3DSA:3.30.310.100 4 134 4.1E-29 T 11-10-2018 IPR036491 YugN-like superfamily AFK25_12480 08bc9f2c70931103e2f8f504be17e684 134 Pfam PF08868 YugN-like family 3 132 3.2E-55 T 11-10-2018 IPR014967 Uncharacterised protein family, YugN-like AFK25_12480 08bc9f2c70931103e2f8f504be17e684 134 SUPERFAMILY SSF160755 1 132 3.79E-38 T 11-10-2018 IPR036491 YugN-like superfamily AFK25_12740 a0d91c1ca3cb78ff31680a1c2cb4d9ba 259 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_12740 a0d91c1ca3cb78ff31680a1c2cb4d9ba 259 Pfam PF00005 ABC transporter 19 171 4.4E-22 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_12740 a0d91c1ca3cb78ff31680a1c2cb4d9ba 259 SMART SM00382 28 223 4.8E-6 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_12740 a0d91c1ca3cb78ff31680a1c2cb4d9ba 259 TIGRFAM TIGR01978 sufC: FeS assembly ATPase SufC 4 244 2.2E-114 T 11-10-2018 IPR010230 FeS cluster assembly SUF system, ATPase SufC GO:0005524 AFK25_12740 a0d91c1ca3cb78ff31680a1c2cb4d9ba 259 Gene3D G3DSA:3.40.50.300 3 248 4.5E-56 T 11-10-2018 AFK25_12740 a0d91c1ca3cb78ff31680a1c2cb4d9ba 259 SUPERFAMILY SSF52540 4 231 4.15E-44 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_07070 67ee444098e21a4cef6ffb0035fc44a2 302 Pfam PF04204 Homoserine O-succinyltransferase 2 299 2.0E-145 T 11-10-2018 IPR033752 MetA family AFK25_07070 67ee444098e21a4cef6ffb0035fc44a2 302 TIGRFAM TIGR01001 metA: homoserine O-succinyltransferase 1 300 5.7E-135 T 11-10-2018 IPR005697 Homoserine O-succinyltransferase MetA GO:0005737|GO:0008899|GO:0019281 AFK25_07070 67ee444098e21a4cef6ffb0035fc44a2 302 ProDom PD037892 HOMOSERINE O-SUCCINYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIOSYNTHESIS TRANSSUCCINYLASE HTS METHIONINE O- AMINO-ACID 36 289 5.0E-124 T 11-10-2018 AFK25_07070 67ee444098e21a4cef6ffb0035fc44a2 302 Hamap MF_00295 Homoserine O-succinyltransferase [metAS]. 31 299 43.844 T 11-10-2018 IPR033752 MetA family AFK25_07070 67ee444098e21a4cef6ffb0035fc44a2 302 Gene3D G3DSA:3.40.50.880 1 300 2.1E-131 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_07070 67ee444098e21a4cef6ffb0035fc44a2 302 SUPERFAMILY SSF52317 17 297 1.6E-104 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_07070 67ee444098e21a4cef6ffb0035fc44a2 302 PIRSF PIRSF000450 1 302 1.2E-150 T 11-10-2018 IPR033752 MetA family AFK25_00485 0bc9e4c4dc774897d0c5cf3e9f8cf168 160 Pfam PF02542 YgbB family 3 156 2.9E-67 T 11-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFK25_00485 0bc9e4c4dc774897d0c5cf3e9f8cf168 160 SUPERFAMILY SSF69765 1 157 2.22E-68 T 11-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFK25_00485 0bc9e4c4dc774897d0c5cf3e9f8cf168 160 TIGRFAM TIGR00151 ispF: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 3 157 2.7E-72 T 11-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFK25_00485 0bc9e4c4dc774897d0c5cf3e9f8cf168 160 Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. 2 157 37.156 T 11-10-2018 IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFK25_00485 0bc9e4c4dc774897d0c5cf3e9f8cf168 160 Gene3D G3DSA:3.30.1330.50 1 160 1.4E-70 T 11-10-2018 IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily GO:0008685|GO:0016114 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFK25_00485 0bc9e4c4dc774897d0c5cf3e9f8cf168 160 ProSitePatterns PS01350 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase signature. 36 51 - T 11-10-2018 IPR020555 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, conserved site GO:0008685 KEGG: 00900+4.6.1.12|MetaCyc: PWY-7560 AFK25_14540 130a252e3c6295993107533a262382ef 234 Gene3D G3DSA:3.40.50.2300 1 130 2.8E-41 T 11-10-2018 AFK25_14540 130a252e3c6295993107533a262382ef 234 SUPERFAMILY SSF46894 132 229 4.46E-32 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFK25_14540 130a252e3c6295993107533a262382ef 234 SMART SM00862 152 228 7.5E-29 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFK25_14540 130a252e3c6295993107533a262382ef 234 Gene3D G3DSA:1.10.10.10 131 234 1.7E-42 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_14540 130a252e3c6295993107533a262382ef 234 Pfam PF00486 Transcriptional regulatory protein, C terminal 152 228 3.1E-28 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFK25_14540 130a252e3c6295993107533a262382ef 234 Pfam PF00072 Response regulator receiver domain 5 114 6.9E-30 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_14540 130a252e3c6295993107533a262382ef 234 SUPERFAMILY SSF52172 2 126 3.56E-45 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_14540 130a252e3c6295993107533a262382ef 234 SMART SM00448 3 113 1.8E-47 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_09985 b2ed65e2328c9609f8be80be8863cc1d 547 SUPERFAMILY SSF52540 169 505 1.09E-54 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_09985 b2ed65e2328c9609f8be80be8863cc1d 547 Gene3D G3DSA:3.40.50.300 318 543 6.8E-48 T 11-10-2018 AFK25_09985 b2ed65e2328c9609f8be80be8863cc1d 547 Gene3D G3DSA:3.40.50.10810 57 317 3.4E-59 T 11-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily AFK25_09985 b2ed65e2328c9609f8be80be8863cc1d 547 SMART SM00487 56 232 6.8E-29 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFK25_09985 b2ed65e2328c9609f8be80be8863cc1d 547 SMART SM00490 378 458 1.5E-21 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_09985 b2ed65e2328c9609f8be80be8863cc1d 547 Pfam PF00271 Helicase conserved C-terminal domain 354 458 3.6E-21 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_09985 b2ed65e2328c9609f8be80be8863cc1d 547 Pfam PF00176 SNF2 family N-terminal domain 78 294 8.1E-36 T 11-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 AFK25_09985 b2ed65e2328c9609f8be80be8863cc1d 547 SUPERFAMILY SSF52540 18 254 1.24E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_10810 df552942c03d9a73cde52d0cfe9effc8 124 TIGRFAM TIGR04086 TIGR04086_membr: putative membrane protein, TIGR04086 family 4 116 5.4E-30 T 11-10-2018 IPR023804 Protein of unknown function DUF3792, transmembrane AFK25_10810 df552942c03d9a73cde52d0cfe9effc8 124 Pfam PF12670 Protein of unknown function (DUF3792) 2 113 6.2E-24 T 11-10-2018 IPR023804 Protein of unknown function DUF3792, transmembrane AFK25_12800 944a119bb1add16c520048cd1c2e2a5b 593 SUPERFAMILY SSF47203 256 421 1.77E-44 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFK25_12800 944a119bb1add16c520048cd1c2e2a5b 593 SUPERFAMILY SSF56645 24 262 2.49E-73 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFK25_12800 944a119bb1add16c520048cd1c2e2a5b 593 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 251 414 2.7E-35 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFK25_12800 944a119bb1add16c520048cd1c2e2a5b 593 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 146 238 5.2E-22 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFK25_12800 944a119bb1add16c520048cd1c2e2a5b 593 Gene3D G3DSA:1.20.140.10 251 420 1.4E-52 T 11-10-2018 AFK25_12800 944a119bb1add16c520048cd1c2e2a5b 593 Gene3D G3DSA:1.20.140.10 422 593 4.4E-59 T 11-10-2018 AFK25_12800 944a119bb1add16c520048cd1c2e2a5b 593 Gene3D G3DSA:2.40.110.10 145 250 1.7E-34 T 11-10-2018 AFK25_12800 944a119bb1add16c520048cd1c2e2a5b 593 Gene3D G3DSA:1.10.540.10 2 144 2.1E-46 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFK25_12800 944a119bb1add16c520048cd1c2e2a5b 593 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 377 396 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFK25_12800 944a119bb1add16c520048cd1c2e2a5b 593 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 30 142 1.5E-30 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFK25_12800 944a119bb1add16c520048cd1c2e2a5b 593 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 148 160 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFK25_10395 e32174b2aedda0564c600245b3d2f79c 380 Pfam PF04055 Radical SAM superfamily 7 176 4.1E-26 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFK25_10395 e32174b2aedda0564c600245b3d2f79c 380 SMART SM00729 2 222 5.1E-66 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFK25_10395 e32174b2aedda0564c600245b3d2f79c 380 Pfam PF06969 HemN C-terminal domain 301 364 1.7E-11 T 11-10-2018 IPR010723 HemN, C-terminal AFK25_10395 e32174b2aedda0564c600245b3d2f79c 380 Gene3D G3DSA:3.80.30.20 3 300 4.7E-107 T 11-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFK25_10395 e32174b2aedda0564c600245b3d2f79c 380 TIGRFAM TIGR00539 hemN_rel: putative oxygen-independent coproporphyrinogen III oxidase 4 366 1.7E-134 T 11-10-2018 IPR004559 Oxygen-independent coproporphyrinogen III oxidase-like GO:0004109|GO:0005737|GO:0006779|GO:0055114 AFK25_10395 e32174b2aedda0564c600245b3d2f79c 380 SUPERFAMILY SSF102114 5 376 1.12E-124 T 11-10-2018 AFK25_04870 fbc56393d648791aa3b9c28607420dfd 429 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 27 56 - T 11-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AFK25_04870 fbc56393d648791aa3b9c28607420dfd 429 SUPERFAMILY SSF51230 1 85 9.42E-28 T 11-10-2018 IPR011053 Single hybrid motif AFK25_04870 fbc56393d648791aa3b9c28607420dfd 429 Gene3D G3DSA:2.40.50.100 2 81 2.4E-28 T 11-10-2018 AFK25_04870 fbc56393d648791aa3b9c28607420dfd 429 Pfam PF00364 Biotin-requiring enzyme 4 75 6.5E-25 T 11-10-2018 IPR000089 Biotin/lipoyl attachment AFK25_04870 fbc56393d648791aa3b9c28607420dfd 429 Gene3D G3DSA:4.10.320.10 108 161 2.4E-23 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 AFK25_04870 fbc56393d648791aa3b9c28607420dfd 429 SUPERFAMILY SSF47005 112 158 2.49E-13 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 AFK25_04870 fbc56393d648791aa3b9c28607420dfd 429 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 199 427 2.4E-91 T 11-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 AFK25_04870 fbc56393d648791aa3b9c28607420dfd 429 SUPERFAMILY SSF52777 188 427 1.16E-90 T 11-10-2018 AFK25_04870 fbc56393d648791aa3b9c28607420dfd 429 Gene3D G3DSA:3.30.559.10 180 425 2.1E-92 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFK25_04870 fbc56393d648791aa3b9c28607420dfd 429 Pfam PF02817 e3 binding domain 119 153 6.6E-15 T 11-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 AFK25_09080 567009dc8614c80b5c5d0ccfb3b4da1d 306 Gene3D G3DSA:1.10.1660.10 2 76 2.7E-23 T 11-10-2018 AFK25_09080 567009dc8614c80b5c5d0ccfb3b4da1d 306 Gene3D G3DSA:1.10.1240.10 91 167 1.2E-23 T 11-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_09080 567009dc8614c80b5c5d0ccfb3b4da1d 306 SUPERFAMILY SSF52242 176 292 2.67E-15 T 11-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFK25_09080 567009dc8614c80b5c5d0ccfb3b4da1d 306 Pfam PF02607 B12 binding domain 93 161 1.8E-12 T 11-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_09080 567009dc8614c80b5c5d0ccfb3b4da1d 306 SMART SM00422 8 77 3.7E-15 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_09080 567009dc8614c80b5c5d0ccfb3b4da1d 306 Pfam PF13411 MerR HTH family regulatory protein 8 76 3.0E-15 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_09080 567009dc8614c80b5c5d0ccfb3b4da1d 306 Gene3D G3DSA:3.40.50.280 174 294 5.6E-19 T 11-10-2018 AFK25_09080 567009dc8614c80b5c5d0ccfb3b4da1d 306 Pfam PF02310 B12 binding domain 176 272 1.5E-13 T 11-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFK25_09080 567009dc8614c80b5c5d0ccfb3b4da1d 306 SUPERFAMILY SSF46955 8 97 4.21E-17 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily AFK25_02765 a83bc016e0285b20d9f03e96185c81c1 293 Gene3D G3DSA:1.10.10.2840 173 293 5.4E-16 T 11-10-2018 AFK25_02765 a83bc016e0285b20d9f03e96185c81c1 293 Pfam PF13556 PucR C-terminal helix-turn-helix domain 232 288 1.9E-17 T 11-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain AFK25_02765 a83bc016e0285b20d9f03e96185c81c1 293 SUPERFAMILY SSF46689 235 265 2.02E-5 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 SUPERFAMILY SSF50249 86 170 1.44E-15 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 Pfam PF00575 S1 RNA binding domain 98 166 6.0E-12 T 11-10-2018 IPR003029 S1 domain GO:0003676 AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 Pfam PF00575 S1 RNA binding domain 13 82 1.2E-11 T 11-10-2018 IPR003029 S1 domain GO:0003676 AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 Pfam PF00575 S1 RNA binding domain 185 255 7.1E-22 T 11-10-2018 IPR003029 S1 domain GO:0003676 AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 Pfam PF00575 S1 RNA binding domain 268 341 5.9E-23 T 11-10-2018 IPR003029 S1 domain GO:0003676 AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 SUPERFAMILY SSF50249 185 271 3.79E-27 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 SUPERFAMILY SSF50249 255 345 1.22E-24 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 Gene3D G3DSA:2.40.50.140 182 261 1.8E-29 T 11-10-2018 AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 Gene3D G3DSA:2.40.50.140 2 93 6.1E-17 T 11-10-2018 AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 SUPERFAMILY SSF50249 7 108 2.13E-19 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 SMART SM00316 13 83 1.2E-14 T 11-10-2018 IPR022967 RNA-binding domain, S1 AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 SMART SM00316 99 166 1.4E-6 T 11-10-2018 IPR022967 RNA-binding domain, S1 AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 SMART SM00316 270 341 8.5E-27 T 11-10-2018 IPR022967 RNA-binding domain, S1 AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 SMART SM00316 185 255 1.8E-27 T 11-10-2018 IPR022967 RNA-binding domain, S1 AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 Gene3D G3DSA:2.40.50.140 262 345 3.1E-27 T 11-10-2018 AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 Gene3D G3DSA:2.40.50.140 94 179 5.5E-11 T 11-10-2018 AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 PRINTS PR00681 Ribosomal protein S1 signature 15 33 3.1E-50 T 11-10-2018 AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 PRINTS PR00681 Ribosomal protein S1 signature 121 138 3.1E-50 T 11-10-2018 AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 PRINTS PR00681 Ribosomal protein S1 signature 80 99 3.1E-50 T 11-10-2018 AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 PRINTS PR00681 Ribosomal protein S1 signature 324 342 3.1E-50 T 11-10-2018 AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 PRINTS PR00681 Ribosomal protein S1 signature 104 120 3.1E-50 T 11-10-2018 AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 PRINTS PR00681 Ribosomal protein S1 signature 150 170 3.1E-50 T 11-10-2018 AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 PRINTS PR00681 Ribosomal protein S1 signature 285 304 3.1E-50 T 11-10-2018 AFK25_09010 880cd165a3dc3a673be68aec606439ec 379 PRINTS PR00681 Ribosomal protein S1 signature 207 228 3.1E-50 T 11-10-2018 AFK25_01770 f9ce6ab8a9d98d2b0a4302679645edcb 277 TIGRFAM TIGR00765 yihY_not_rbn: YihY family inner membrane protein 9 265 9.1E-60 T 11-10-2018 IPR017039 Virulence factor BrkB AFK25_01770 f9ce6ab8a9d98d2b0a4302679645edcb 277 Pfam PF03631 Virulence factor BrkB 17 265 8.8E-70 T 11-10-2018 IPR017039 Virulence factor BrkB AFK25_01770 f9ce6ab8a9d98d2b0a4302679645edcb 277 PIRSF PIRSF035875 4 274 2.9E-83 T 11-10-2018 IPR017039 Virulence factor BrkB AFK25_05305 59c8c8ec673415ac988cc1a32b30c045 257 Gene3D G3DSA:3.30.70.330 80 166 1.1E-29 T 11-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily AFK25_05305 59c8c8ec673415ac988cc1a32b30c045 257 Gene3D G3DSA:3.30.1370.160 2 79 8.3E-29 T 11-10-2018 AFK25_05305 59c8c8ec673415ac988cc1a32b30c045 257 Gene3D G3DSA:3.10.290.10 175 231 3.5E-8 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFK25_05305 59c8c8ec673415ac988cc1a32b30c045 257 Pfam PF01479 S4 domain 182 226 1.0E-5 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_05305 59c8c8ec673415ac988cc1a32b30c045 257 SUPERFAMILY SSF55174 35 251 1.7E-32 T 11-10-2018 AFK25_05305 59c8c8ec673415ac988cc1a32b30c045 257 SMART SM00363 181 238 4.4E-7 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_10825 76600777a0417762cafb8cf5cfd527f3 343 Gene3D G3DSA:3.40.1780.10 14 342 1.8E-135 T 11-10-2018 AFK25_10825 76600777a0417762cafb8cf5cfd527f3 343 SUPERFAMILY SSF111337 1 343 2.35E-141 T 11-10-2018 IPR036100 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA superfamily GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 AFK25_10825 76600777a0417762cafb8cf5cfd527f3 343 Gene3D G3DSA:2.40.10.240 65 163 1.8E-135 T 11-10-2018 AFK25_10825 76600777a0417762cafb8cf5cfd527f3 343 TIGRFAM TIGR00113 queA: S-adenosylmethionine:tRNA ribosyltransferase-isomerase 1 343 5.5E-149 T 11-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 AFK25_10825 76600777a0417762cafb8cf5cfd527f3 343 Pfam PF02547 Queuosine biosynthesis protein 4 342 1.6E-142 T 11-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 AFK25_10825 76600777a0417762cafb8cf5cfd527f3 343 Hamap MF_00113 S-adenosylmethionine:tRNA ribosyltransferase-isomerase [queA]. 1 343 47.184 T 11-10-2018 IPR003699 S-adenosylmethionine:tRNA ribosyltransferase-isomerase, QueA GO:0008616|GO:0016740|GO:0016853 MetaCyc: PWY-6700 AFK25_11620 4099edc9d675ef4b2b7dd9324de3e1ca 151 Pfam PF04284 Protein of unknown function (DUF441) 5 144 1.3E-47 T 11-10-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame AFK25_11620 4099edc9d675ef4b2b7dd9324de3e1ca 151 ProDom PD021096 MEMBRANE YEAL PRECURSOR SIGNAL PROTEIN TRANSMEMBRANE YTWI HI1074 INTEGRAL SPANNING 19 129 3.0E-37 T 11-10-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame AFK25_11620 4099edc9d675ef4b2b7dd9324de3e1ca 151 Hamap MF_01874 UPF0756 membrane protein YeaL [yeaL]. 1 147 19.07 T 11-10-2018 IPR007382 Uncharacterised protein family UPF0756, transmembrame AFK25_03340 feafeaabaa5bb8f87f260673bd29e6ee 277 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 218 272 1.2E-21 T 11-10-2018 IPR019264 Domain of unknown function DUF2179 AFK25_03340 feafeaabaa5bb8f87f260673bd29e6ee 277 PIRSF PIRSF006483 1 277 1.5E-97 T 11-10-2018 IPR003740 Uncharacterised membrane protein YitT AFK25_03340 feafeaabaa5bb8f87f260673bd29e6ee 277 Gene3D G3DSA:3.30.70.120 189 264 2.6E-20 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AFK25_03340 feafeaabaa5bb8f87f260673bd29e6ee 277 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 6 212 3.0E-60 T 11-10-2018 IPR003740 Uncharacterised membrane protein YitT AFK25_14595 6ee26f39507dd3317abd33b66a4f3ea2 366 SUPERFAMILY SSF81271 282 363 1.26E-36 T 11-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AFK25_14595 6ee26f39507dd3317abd33b66a4f3ea2 366 Gene3D G3DSA:3.10.20.30 48 364 3.8E-160 T 11-10-2018 IPR012675 Beta-grasp domain superfamily AFK25_14595 6ee26f39507dd3317abd33b66a4f3ea2 366 SUPERFAMILY SSF52540 3 304 3.9E-88 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_14595 6ee26f39507dd3317abd33b66a4f3ea2 366 TIGRFAM TIGR00092 TIGR00092: GTP-binding protein YchF 1 366 8.1E-158 T 11-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 AFK25_14595 6ee26f39507dd3317abd33b66a4f3ea2 366 Pfam PF01926 50S ribosome-binding GTPase 5 121 2.1E-23 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_14595 6ee26f39507dd3317abd33b66a4f3ea2 366 PIRSF PIRSF006641 1 366 2.5E-167 T 11-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 AFK25_14595 6ee26f39507dd3317abd33b66a4f3ea2 366 Hamap MF_00944 Ribosome-binding ATPase YchF [ychF]. 2 366 46.773 T 11-10-2018 IPR004396 Ribosome-binding ATPase YchF/Obg-like ATPase 1 GO:0005525 Reactome: R-HSA-114608 AFK25_14595 6ee26f39507dd3317abd33b66a4f3ea2 366 Gene3D G3DSA:1.10.150.300 113 200 3.8E-160 T 11-10-2018 IPR023192 TGS-like domain superfamily Reactome: R-HSA-114608 AFK25_14595 6ee26f39507dd3317abd33b66a4f3ea2 366 Pfam PF06071 Protein of unknown function (DUF933) 282 365 2.4E-41 T 11-10-2018 IPR013029 YchF, C-terminal domain Reactome: R-HSA-114608 AFK25_14595 6ee26f39507dd3317abd33b66a4f3ea2 366 Gene3D G3DSA:3.40.50.300 4 281 3.8E-160 T 11-10-2018 AFK25_14595 6ee26f39507dd3317abd33b66a4f3ea2 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 26 44 9.7E-36 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_14595 6ee26f39507dd3317abd33b66a4f3ea2 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 70 85 9.7E-36 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_14595 6ee26f39507dd3317abd33b66a4f3ea2 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 5 25 9.7E-36 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_14595 6ee26f39507dd3317abd33b66a4f3ea2 366 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 9.7E-36 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_14125 f52e8dfbcd04497e1e4033d01a11c6aa 248 Gene3D G3DSA:3.30.70.1030 1 137 5.8E-59 T 11-10-2018 AFK25_14125 f52e8dfbcd04497e1e4033d01a11c6aa 248 Hamap MF_01442 Putative heme-dependent peroxidase . 1 248 57.35 T 11-10-2018 IPR031332 Putative heme-dependent peroxidase, UPF0447 family AFK25_14125 f52e8dfbcd04497e1e4033d01a11c6aa 248 Gene3D G3DSA:3.30.70.1100 138 248 8.4E-48 T 11-10-2018 AFK25_14125 f52e8dfbcd04497e1e4033d01a11c6aa 248 SUPERFAMILY SSF54909 1 247 2.39E-94 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel AFK25_14125 f52e8dfbcd04497e1e4033d01a11c6aa 248 Pfam PF06778 Chlorite dismutase 33 236 1.8E-76 T 11-10-2018 IPR010644 Putative heme-dependent peroxidase/Chlorite dismutase AFK25_00755 f786d5b6b78f678c1701149839934f40 289 ProSitePatterns PS00211 ABC transporters family signature. 146 160 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_00755 f786d5b6b78f678c1701149839934f40 289 Gene3D G3DSA:3.40.50.300 1 280 1.8E-75 T 11-10-2018 AFK25_00755 f786d5b6b78f678c1701149839934f40 289 TIGRFAM TIGR04521 ECF_ATPase_2: energy-coupling factor transporter ATPase 3 280 5.1E-121 T 11-10-2018 IPR030946 Energy-coupling factor transporter ATP-binding protein EcfA2 AFK25_00755 f786d5b6b78f678c1701149839934f40 289 SMART SM00382 32 223 2.6E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_00755 f786d5b6b78f678c1701149839934f40 289 SUPERFAMILY SSF52540 3 239 1.66E-59 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_00755 f786d5b6b78f678c1701149839934f40 289 Pfam PF00005 ABC transporter 25 174 6.0E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_11640 abf7cfe86e883410420a72e68932366f 319 Gene3D G3DSA:3.40.50.450 3 279 1.1E-124 T 11-10-2018 AFK25_11640 abf7cfe86e883410420a72e68932366f 319 TIGRFAM TIGR02482 PFKA_ATP: 6-phosphofructokinase 3 299 3.8E-144 T 11-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 AFK25_11640 abf7cfe86e883410420a72e68932366f 319 Hamap MF_00339 ATP-dependent 6-phosphofructokinase [pfkA]. 1 318 50.615 T 11-10-2018 IPR012828 ATP-dependent 6-phosphofructokinase, prokaryotic GO:0003872|GO:0005524|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 AFK25_11640 abf7cfe86e883410420a72e68932366f 319 PIRSF PIRSF000532 1 319 4.3E-127 T 11-10-2018 IPR012003 ATP-dependent 6-phosphofructokinase, prokaryotic-type GO:0005524|GO:0006002|GO:0006096|GO:0008443 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385 AFK25_11640 abf7cfe86e883410420a72e68932366f 319 Gene3D G3DSA:3.40.50.460 142 251 1.1E-124 T 11-10-2018 AFK25_11640 abf7cfe86e883410420a72e68932366f 319 SUPERFAMILY SSF53784 1 315 1.18E-122 T 11-10-2018 IPR035966 Phosphofructokinase superfamily GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFK25_11640 abf7cfe86e883410420a72e68932366f 319 Pfam PF00365 Phosphofructokinase 3 275 3.1E-116 T 11-10-2018 IPR000023 Phosphofructokinase domain GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFK25_11640 abf7cfe86e883410420a72e68932366f 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 176 193 4.1E-93 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFK25_11640 abf7cfe86e883410420a72e68932366f 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 6 25 4.1E-93 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFK25_11640 abf7cfe86e883410420a72e68932366f 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 31 44 4.1E-93 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFK25_11640 abf7cfe86e883410420a72e68932366f 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 120 137 4.1E-93 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFK25_11640 abf7cfe86e883410420a72e68932366f 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 138 156 4.1E-93 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFK25_11640 abf7cfe86e883410420a72e68932366f 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 212 224 4.1E-93 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFK25_11640 abf7cfe86e883410420a72e68932366f 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 239 261 4.1E-93 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFK25_11640 abf7cfe86e883410420a72e68932366f 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 93 109 4.1E-93 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFK25_11640 abf7cfe86e883410420a72e68932366f 319 PRINTS PR00476 ATP-dependent phosphofructokinase family signature 158 174 4.1E-93 T 11-10-2018 IPR022953 ATP-dependent 6-phosphofructokinase GO:0003872|GO:0006002|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFK25_11640 abf7cfe86e883410420a72e68932366f 319 ProSitePatterns PS00433 Phosphofructokinase signature. 243 261 - T 11-10-2018 IPR015912 Phosphofructokinase, conserved site GO:0003872|GO:0006096 KEGG: 00010+2.7.1.11|KEGG: 00030+2.7.1.11|KEGG: 00051+2.7.1.11|KEGG: 00052+2.7.1.11|KEGG: 00680+2.7.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-7385|Reactome: R-HSA-70171 AFK25_12630 9719cd691c2b887ddf872be2bd60bcd2 323 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 228 244 - T 11-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AFK25_12630 9719cd691c2b887ddf872be2bd60bcd2 323 SUPERFAMILY SSF52283 3 137 9.07E-37 T 11-10-2018 AFK25_12630 9719cd691c2b887ddf872be2bd60bcd2 323 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 111 289 1.9E-65 T 11-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AFK25_12630 9719cd691c2b887ddf872be2bd60bcd2 323 Gene3D G3DSA:3.40.50.720 6 316 5.8E-126 T 11-10-2018 AFK25_12630 9719cd691c2b887ddf872be2bd60bcd2 323 SUPERFAMILY SSF51735 105 289 6.27E-62 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_12630 9719cd691c2b887ddf872be2bd60bcd2 323 Gene3D G3DSA:3.40.50.720 100 289 5.8E-126 T 11-10-2018 AFK25_12630 9719cd691c2b887ddf872be2bd60bcd2 323 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 151 178 - T 11-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 AFK25_12630 9719cd691c2b887ddf872be2bd60bcd2 323 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 6 320 2.5E-34 T 11-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 AFK25_10455 e08c555885d6df39d67d789713bd0c07 277 Gene3D G3DSA:3.40.50.720 1 160 6.5E-37 T 11-10-2018 AFK25_10455 e08c555885d6df39d67d789713bd0c07 277 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 266 17.238 T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AFK25_10455 e08c555885d6df39d67d789713bd0c07 277 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AFK25_10455 e08c555885d6df39d67d789713bd0c07 277 SUPERFAMILY SSF48179 158 265 2.21E-20 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFK25_10455 e08c555885d6df39d67d789713bd0c07 277 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 163 260 2.6E-18 T 11-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AFK25_10455 e08c555885d6df39d67d789713bd0c07 277 SUPERFAMILY SSF51735 2 157 4.72E-26 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_10455 e08c555885d6df39d67d789713bd0c07 277 PIRSF PIRSF000193 1 266 8.1E-73 T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AFK25_10455 e08c555885d6df39d67d789713bd0c07 277 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 3 97 2.2E-20 T 11-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal AFK25_10455 e08c555885d6df39d67d789713bd0c07 277 Gene3D G3DSA:1.10.3730.10 161 263 2.8E-17 T 11-10-2018 AFK25_07495 60eeccef6bca19c7be8ac31ca5ab3066 453 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 243 258 - T 11-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AFK25_07495 60eeccef6bca19c7be8ac31ca5ab3066 453 SUPERFAMILY SSF55931 116 449 4.81E-124 T 11-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFK25_07495 60eeccef6bca19c7be8ac31ca5ab3066 453 SMART SM01230 115 363 2.2E-136 T 11-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFK25_07495 60eeccef6bca19c7be8ac31ca5ab3066 453 SUPERFAMILY SSF54368 14 113 6.54E-27 T 11-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFK25_07495 60eeccef6bca19c7be8ac31ca5ab3066 453 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 27 109 2.9E-26 T 11-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AFK25_07495 60eeccef6bca19c7be8ac31ca5ab3066 453 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 16 449 7.4E-165 T 11-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFK25_07495 60eeccef6bca19c7be8ac31ca5ab3066 453 Gene3D G3DSA:3.10.20.70 12 117 1.0E-34 T 11-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFK25_07495 60eeccef6bca19c7be8ac31ca5ab3066 453 Gene3D G3DSA:3.30.590.10 118 453 1.3E-136 T 11-10-2018 AFK25_07495 60eeccef6bca19c7be8ac31ca5ab3066 453 Pfam PF00120 Glutamine synthetase, catalytic domain 116 449 6.6E-138 T 11-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AFK25_08835 eb11499c85f775352ee9259766a10492 255 Pfam PF00032 Cytochrome b(C-terminal)/b6/petD 71 157 6.3E-10 T 11-10-2018 IPR005798 Cytochrome b/b6, C-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 AFK25_08835 eb11499c85f775352ee9259766a10492 255 Gene3D G3DSA:1.20.810.10 14 169 2.4E-26 T 11-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 AFK25_08835 eb11499c85f775352ee9259766a10492 255 Gene3D G3DSA:1.10.760.10 182 253 9.5E-17 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFK25_08835 eb11499c85f775352ee9259766a10492 255 SUPERFAMILY SSF46626 142 252 3.01E-15 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFK25_08835 eb11499c85f775352ee9259766a10492 255 SUPERFAMILY SSF81648 21 156 3.79E-31 T 11-10-2018 IPR036150 Cytochrome b/b6, C-terminal domain superfamily GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 AFK25_08835 eb11499c85f775352ee9259766a10492 255 PIRSF PIRSF036636 1 255 1.4E-149 T 11-10-2018 IPR012049 Menaquinone:cytochrome c reductase, cytochrome b/c subunit GO:0005506|GO:0009055|GO:0016021|GO:0020037 AFK25_08835 eb11499c85f775352ee9259766a10492 255 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 181 249 3.7E-14 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_07140 9898f542ec2916353601406d973f870e 759 Gene3D G3DSA:3.30.420.360 381 749 1.6E-125 T 11-10-2018 AFK25_07140 9898f542ec2916353601406d973f870e 759 Pfam PF07503 HypF finger 107 140 3.4E-17 T 11-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 AFK25_07140 9898f542ec2916353601406d973f870e 759 Pfam PF07503 HypF finger 157 189 1.9E-16 T 11-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 AFK25_07140 9898f542ec2916353601406d973f870e 759 ProSitePatterns PS00150 Acylphosphatase signature 1. 9 19 - T 11-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AFK25_07140 9898f542ec2916353601406d973f870e 759 PIRSF PIRSF006256 1 758 6.8E-288 T 11-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 AFK25_07140 9898f542ec2916353601406d973f870e 759 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 7 750 9.1E-255 T 11-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 AFK25_07140 9898f542ec2916353601406d973f870e 759 SUPERFAMILY SSF55821 174 388 7.63E-53 T 11-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AFK25_07140 9898f542ec2916353601406d973f870e 759 Gene3D G3DSA:3.30.420.350 480 736 1.6E-125 T 11-10-2018 AFK25_07140 9898f542ec2916353601406d973f870e 759 Pfam PF00708 Acylphosphatase 6 88 2.3E-20 T 11-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AFK25_07140 9898f542ec2916353601406d973f870e 759 Gene3D G3DSA:3.30.110.120 251 369 1.6E-152 T 11-10-2018 AFK25_07140 9898f542ec2916353601406d973f870e 759 SUPERFAMILY SSF54975 2 89 5.67E-23 T 11-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AFK25_07140 9898f542ec2916353601406d973f870e 759 Pfam PF01300 Telomere recombination 208 382 3.6E-57 T 11-10-2018 IPR006070 YrdC-like domain GO:0003725 AFK25_07140 9898f542ec2916353601406d973f870e 759 Gene3D G3DSA:3.90.870.50 7 360 1.6E-152 T 11-10-2018 AFK25_00475 d7e2eb4c2f8264acc8653cae7510223d 362 SMART SM00670 162 269 3.2E-14 T 11-10-2018 IPR002716 PIN domain AFK25_00475 d7e2eb4c2f8264acc8653cae7510223d 362 Gene3D G3DSA:3.40.50.1010 158 292 1.8E-53 T 11-10-2018 AFK25_00475 d7e2eb4c2f8264acc8653cae7510223d 362 Pfam PF01938 TRAM domain 294 346 7.1E-7 T 11-10-2018 IPR002792 TRAM domain AFK25_00475 d7e2eb4c2f8264acc8653cae7510223d 362 SUPERFAMILY SSF88723 164 290 1.69E-24 T 11-10-2018 IPR029060 PIN-like domain superfamily AFK25_10000 e8ac9cca5fea2414c21f2bb3b7cef0a3 168 Hamap MF_00109 Shikimate kinase [aroK]. 1 164 28.353 T 11-10-2018 IPR000623 Shikimate kinase/Threonine synthase-like 1 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AFK25_10000 e8ac9cca5fea2414c21f2bb3b7cef0a3 168 SUPERFAMILY SSF52540 4 160 2.67E-31 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_10000 e8ac9cca5fea2414c21f2bb3b7cef0a3 168 PRINTS PR01100 Shikimate kinase family signature 73 82 2.5E-24 T 11-10-2018 AFK25_10000 e8ac9cca5fea2414c21f2bb3b7cef0a3 168 PRINTS PR01100 Shikimate kinase family signature 56 64 2.5E-24 T 11-10-2018 AFK25_10000 e8ac9cca5fea2414c21f2bb3b7cef0a3 168 PRINTS PR01100 Shikimate kinase family signature 94 111 2.5E-24 T 11-10-2018 AFK25_10000 e8ac9cca5fea2414c21f2bb3b7cef0a3 168 PRINTS PR01100 Shikimate kinase family signature 4 19 2.5E-24 T 11-10-2018 AFK25_10000 e8ac9cca5fea2414c21f2bb3b7cef0a3 168 PRINTS PR01100 Shikimate kinase family signature 28 41 2.5E-24 T 11-10-2018 AFK25_10000 e8ac9cca5fea2414c21f2bb3b7cef0a3 168 Gene3D G3DSA:3.40.50.300 1 166 1.5E-56 T 11-10-2018 AFK25_10000 e8ac9cca5fea2414c21f2bb3b7cef0a3 168 Pfam PF01202 Shikimate kinase 10 163 9.2E-51 T 11-10-2018 IPR031322 Shikimate kinase/gluconokinase KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AFK25_02900 6ce8a32b1dd27d49e578b55531befc27 339 Gene3D G3DSA:3.40.50.2300 66 306 6.3E-77 T 11-10-2018 AFK25_02900 6ce8a32b1dd27d49e578b55531befc27 339 SUPERFAMILY SSF53822 62 330 2.19E-76 T 11-10-2018 IPR028082 Periplasmic binding protein-like I AFK25_02900 6ce8a32b1dd27d49e578b55531befc27 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 7.2E-18 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_02900 6ce8a32b1dd27d49e578b55531befc27 339 SUPERFAMILY SSF47413 1 59 6.97E-19 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFK25_02900 6ce8a32b1dd27d49e578b55531befc27 339 Pfam PF13377 Periplasmic binding protein-like domain 168 329 6.4E-38 T 11-10-2018 AFK25_02900 6ce8a32b1dd27d49e578b55531befc27 339 Gene3D G3DSA:3.40.50.2300 159 288 6.3E-77 T 11-10-2018 AFK25_02900 6ce8a32b1dd27d49e578b55531befc27 339 Gene3D G3DSA:1.10.260.40 1 59 2.6E-23 T 11-10-2018 AFK25_02900 6ce8a32b1dd27d49e578b55531befc27 339 SMART SM00354 1 71 2.7E-31 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_05030 f44d87e4369a4edfe14c2048c8550fe4 206 Gene3D G3DSA:1.20.120.80 21 205 2.8E-53 T 11-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05030 f44d87e4369a4edfe14c2048c8550fe4 206 Pfam PF00510 Cytochrome c oxidase subunit III 28 203 2.5E-18 T 11-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05030 f44d87e4369a4edfe14c2048c8550fe4 206 SUPERFAMILY SSF81452 19 203 1.31E-55 T 11-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 631 649 - T 11-10-2018 IPR028299 ClpA/B, conserved site 2 AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 204 336 1.9E-13 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 96 146 2.9E-15 T 11-10-2018 IPR004176 Clp, N-terminal AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 Pfam PF02861 Clp amino terminal domain, pathogenicity island component 17 60 6.2E-9 T 11-10-2018 IPR004176 Clp, N-terminal AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 SMART SM01086 768 857 4.3E-36 T 11-10-2018 IPR019489 Clp ATPase, C-terminal AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 Gene3D G3DSA:3.40.50.300 550 766 1.2E-89 T 11-10-2018 AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 Gene3D G3DSA:3.40.50.300 344 544 1.3E-75 T 11-10-2018 AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 SUPERFAMILY SSF52540 158 545 4.85E-104 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 Pfam PF07724 AAA domain (Cdc48 subfamily) 596 762 4.5E-57 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 601 619 8.5E-43 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 708 722 8.5E-43 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 675 693 8.5E-43 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 646 664 8.5E-43 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 SUPERFAMILY SSF81923 5 156 7.36E-40 T 11-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 295 307 - T 11-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 TIGRFAM TIGR03346 chaperone_ClpB: ATP-dependent chaperone protein ClpB 6 857 0.0 T 11-10-2018 IPR017730 Chaperonin ClpB GO:0005737|GO:0009408|GO:0042026 AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 SMART SM00382 597 748 6.1E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 SMART SM00382 199 345 3.8E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 Gene3D G3DSA:3.40.50.300 150 343 6.5E-75 T 11-10-2018 AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 SUPERFAMILY SSF52540 546 855 6.95E-85 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 768 848 7.8E-26 T 11-10-2018 IPR019489 Clp ATPase, C-terminal AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 Gene3D G3DSA:1.10.8.60 768 859 8.9E-29 T 11-10-2018 AFK25_03405 1abc1c5f38a160bbedfc66fac9618cb2 860 Gene3D G3DSA:1.10.1780.10 1 149 1.4E-35 T 11-10-2018 IPR036628 Clp, N-terminal domain superfamily GO:0019538 AFK25_14305 cca4fbf6949fb2a403dd6932ca992598 164 Pfam PF08281 Sigma-70, region 4 100 152 3.6E-14 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFK25_14305 cca4fbf6949fb2a403dd6932ca992598 164 SUPERFAMILY SSF88659 97 155 1.61E-12 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFK25_14305 cca4fbf6949fb2a403dd6932ca992598 164 Gene3D G3DSA:1.10.1740.10 3 81 3.1E-16 T 11-10-2018 AFK25_14305 cca4fbf6949fb2a403dd6932ca992598 164 Gene3D G3DSA:1.10.10.10 94 160 1.2E-12 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_14305 cca4fbf6949fb2a403dd6932ca992598 164 Pfam PF04542 Sigma-70 region 2 14 80 1.1E-11 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_14305 cca4fbf6949fb2a403dd6932ca992598 164 SUPERFAMILY SSF88946 5 86 5.49E-16 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_02665 dceac86b3e8fce65375a778f946023db 554 Gene3D G3DSA:3.20.20.80 171 476 3.4E-131 T 11-10-2018 AFK25_02665 dceac86b3e8fce65375a778f946023db 554 Gene3D G3DSA:2.60.40.1180 477 554 1.8E-23 T 11-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFK25_02665 dceac86b3e8fce65375a778f946023db 554 Pfam PF00128 Alpha amylase, catalytic domain 28 373 1.3E-122 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFK25_02665 dceac86b3e8fce65375a778f946023db 554 Gene3D G3DSA:3.20.20.80 1 109 1.8E-52 T 11-10-2018 AFK25_02665 dceac86b3e8fce65375a778f946023db 554 SUPERFAMILY SSF51445 3 473 7.26E-166 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily AFK25_02665 dceac86b3e8fce65375a778f946023db 554 SUPERFAMILY SSF51011 476 552 1.11E-16 T 11-10-2018 AFK25_02665 dceac86b3e8fce65375a778f946023db 554 Gene3D G3DSA:3.90.400.10 110 170 1.8E-35 T 11-10-2018 AFK25_02665 dceac86b3e8fce65375a778f946023db 554 Pfam PF16657 Maltogenic Amylase, C-terminal domain 476 549 2.5E-7 T 11-10-2018 IPR032091 Maltogenic Amylase, C-terminal AFK25_02665 dceac86b3e8fce65375a778f946023db 554 SMART SM00642 13 415 4.8E-174 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFK25_04565 e6927506aaeb4a909326cfc3983c51eb 200 Gene3D G3DSA:3.40.109.10 1 199 1.0E-56 T 11-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFK25_04565 e6927506aaeb4a909326cfc3983c51eb 200 SUPERFAMILY SSF55469 2 199 8.64E-55 T 11-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AFK25_04565 e6927506aaeb4a909326cfc3983c51eb 200 Pfam PF00881 Nitroreductase family 6 179 6.9E-35 T 11-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 AFK25_10170 12e5a26552e48ba8e50166e166187363 404 Gene3D G3DSA:1.20.1250.20 9 397 1.5E-23 T 11-10-2018 AFK25_10170 12e5a26552e48ba8e50166e166187363 404 Pfam PF07690 Major Facilitator Superfamily 25 339 5.0E-18 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFK25_10170 12e5a26552e48ba8e50166e166187363 404 SUPERFAMILY SSF103473 12 400 6.8E-29 T 11-10-2018 IPR036259 MFS transporter superfamily AFK25_07870 8b19b8c4fd8eed0874e79763157de1f6 318 SUPERFAMILY SSF54060 153 302 3.18E-41 T 11-10-2018 AFK25_07870 8b19b8c4fd8eed0874e79763157de1f6 318 Pfam PF04231 Endonuclease I 162 302 5.8E-34 T 11-10-2018 IPR007346 Endonuclease I GO:0004518 AFK25_08475 567fd40ce91e3cd9f5d06ef11a7044f8 380 PIRSF PIRSF037420 3 379 1.0E-97 T 11-10-2018 IPR017200 Coenzyme PQQ synthesis protein E AFK25_08475 567fd40ce91e3cd9f5d06ef11a7044f8 380 SUPERFAMILY SSF102114 13 344 2.62E-65 T 11-10-2018 AFK25_08475 567fd40ce91e3cd9f5d06ef11a7044f8 380 Gene3D G3DSA:3.20.20.70 9 327 1.4E-46 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_08475 567fd40ce91e3cd9f5d06ef11a7044f8 380 TIGRFAM TIGR04053 sam_11: radical SAM protein, BA_1875 family 8 367 1.6E-153 T 11-10-2018 IPR027634 Radical SAM protein, BA_1875 family AFK25_08475 567fd40ce91e3cd9f5d06ef11a7044f8 380 SMART SM00729 15 214 0.0018 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFK25_08475 567fd40ce91e3cd9f5d06ef11a7044f8 380 Pfam PF04055 Radical SAM superfamily 20 178 7.6E-17 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFK25_06460 dfbf48f53733a3a4b85526d34eb540dd 254 SUPERFAMILY SSF46785 7 80 7.05E-21 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_06460 dfbf48f53733a3a4b85526d34eb540dd 254 SMART SM00346 7 97 1.9E-31 T 11-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFK25_06460 dfbf48f53733a3a4b85526d34eb540dd 254 Gene3D G3DSA:1.10.10.10 5 81 2.6E-26 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_06460 dfbf48f53733a3a4b85526d34eb540dd 254 Gene3D G3DSA:3.30.450.40 82 254 1.5E-68 T 11-10-2018 IPR029016 GAF-like domain superfamily AFK25_06460 dfbf48f53733a3a4b85526d34eb540dd 254 Pfam PF01614 Bacterial transcriptional regulator 124 249 8.5E-43 T 11-10-2018 IPR014757 Transcription regulator IclR, C-terminal AFK25_06460 dfbf48f53733a3a4b85526d34eb540dd 254 SUPERFAMILY SSF55781 65 253 2.0E-58 T 11-10-2018 AFK25_06460 dfbf48f53733a3a4b85526d34eb540dd 254 Pfam PF09339 IclR helix-turn-helix domain 9 59 8.1E-21 T 11-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 Gene3D G3DSA:1.10.287.130 350 429 2.4E-27 T 11-10-2018 AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 SUPERFAMILY SSF47384 344 425 8.44E-22 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 Gene3D G3DSA:3.30.450.20 35 150 5.9E-6 T 11-10-2018 AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 SMART SM00304 183 235 1.1E-6 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 SUPERFAMILY SSF55785 232 350 2.09E-12 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 471 580 6.8E-30 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 Gene3D G3DSA:3.30.450.20 242 349 1.3E-13 T 11-10-2018 AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 SMART SM00091 242 309 7.2E-8 T 11-10-2018 IPR000014 PAS domain AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 Pfam PF16736 Single Cache-like 33 148 4.6E-39 T 11-10-2018 IPR031967 PhoR, single Cache-like domain AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 SUPERFAMILY SSF55874 414 579 5.11E-53 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 Pfam PF00512 His Kinase A (phospho-acceptor) domain 358 424 6.2E-21 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 SMART SM00388 358 425 4.4E-24 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 240 358 3.8E-8 T 11-10-2018 IPR000014 PAS domain AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 SUPERFAMILY SSF158472 185 234 2.09E-8 T 11-10-2018 AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 Pfam PF00989 PAS fold 243 349 2.0E-15 T 11-10-2018 IPR013767 PAS fold GO:0006355 AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 SMART SM00387 471 583 3.5E-44 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 Gene3D G3DSA:1.20.1480.50 151 241 4.5E-11 T 11-10-2018 AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 526 536 1.2E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 508 522 1.2E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 543 561 1.2E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 567 580 1.2E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_11590 1bdb1548a49a3ab0c5ec5e4b3d50379a 587 Gene3D G3DSA:3.30.565.10 431 584 4.0E-51 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_05185 e016b7791d23462b5b473c04115c015c 310 Pfam PF01795 MraW methylase family 2 309 1.1E-136 T 11-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 AFK25_05185 e016b7791d23462b5b473c04115c015c 310 PIRSF PIRSF004486 2 310 4.5E-113 T 11-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 AFK25_05185 e016b7791d23462b5b473c04115c015c 310 SUPERFAMILY SSF81799 113 214 6.54E-37 T 11-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 AFK25_05185 e016b7791d23462b5b473c04115c015c 310 Gene3D G3DSA:1.10.150.170 111 215 3.9E-109 T 11-10-2018 IPR023397 S-adenosyl-L-methionine-dependent methyltransferase, MraW, recognition domain superfamily GO:0008168 AFK25_05185 e016b7791d23462b5b473c04115c015c 310 SUPERFAMILY SSF53335 3 310 1.12E-47 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_05185 e016b7791d23462b5b473c04115c015c 310 TIGRFAM TIGR00006 TIGR00006: 16S rRNA (cytosine(1402)-N(4))-methyltransferase 3 309 5.8E-130 T 11-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 AFK25_05185 e016b7791d23462b5b473c04115c015c 310 Gene3D G3DSA:3.40.50.150 7 309 3.9E-109 T 11-10-2018 AFK25_05185 e016b7791d23462b5b473c04115c015c 310 Hamap MF_01007 Ribosomal RNA small subunit methyltransferase H [rsmH]. 4 310 39.806 T 11-10-2018 IPR002903 Ribosomal RNA small subunit methyltransferase H GO:0008168 AFK25_00555 c950abcc1fb428d19259ba0016656d1e 121 Hamap MF_00368 50S ribosomal protein L7/L12 [rplL]. 1 121 26.483 T 11-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00555 c950abcc1fb428d19259ba0016656d1e 121 Pfam PF00542 Ribosomal protein L7/L12 C-terminal domain 55 121 2.2E-32 T 11-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00555 c950abcc1fb428d19259ba0016656d1e 121 SUPERFAMILY SSF48300 1 57 2.62E-19 T 11-10-2018 IPR036235 Ribosomal protein L7/L12, oligomerisation domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00555 c950abcc1fb428d19259ba0016656d1e 121 TIGRFAM TIGR00855 L12: ribosomal protein bL12 2 121 2.8E-52 T 11-10-2018 IPR000206 Ribosomal protein L7/L12 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00555 c950abcc1fb428d19259ba0016656d1e 121 Gene3D G3DSA:3.30.1390.10 52 121 1.4E-33 T 11-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like AFK25_00555 c950abcc1fb428d19259ba0016656d1e 121 Pfam PF16320 Ribosomal protein L7/L12 dimerisation domain 2 49 3.6E-22 T 11-10-2018 IPR008932 Ribosomal protein L7/L12, oligomerisation GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00555 c950abcc1fb428d19259ba0016656d1e 121 ProDom PD001326 RIBOSOMAL L7/L12 50S RIBONUCLEOPROTEIN CHLOROPLAST L12 PLASTID DIRECT SEQUENCING PEPTIDE 56 100 1.0E-16 T 11-10-2018 IPR013823 Ribosomal protein L7/L12, C-terminal GO:0003735|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00555 c950abcc1fb428d19259ba0016656d1e 121 Gene3D G3DSA:1.20.5.710 1 51 2.8E-23 T 11-10-2018 AFK25_00555 c950abcc1fb428d19259ba0016656d1e 121 SUPERFAMILY SSF54736 50 121 1.67E-26 T 11-10-2018 IPR014719 Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like AFK25_00495 7e9cc26ca8260e227119129eb76c50c8 221 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 126 154 - T 11-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 AFK25_00495 7e9cc26ca8260e227119129eb76c50c8 221 Gene3D G3DSA:2.160.10.10 67 183 3.2E-39 T 11-10-2018 AFK25_00495 7e9cc26ca8260e227119129eb76c50c8 221 TIGRFAM TIGR01172 cysE: serine O-acetyltransferase 6 166 4.4E-81 T 11-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 AFK25_00495 7e9cc26ca8260e227119129eb76c50c8 221 PIRSF PIRSF000441 1 218 2.0E-88 T 11-10-2018 IPR005881 Serine O-acetyltransferase GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 AFK25_00495 7e9cc26ca8260e227119129eb76c50c8 221 SUPERFAMILY SSF51161 4 168 7.07E-60 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily AFK25_00495 7e9cc26ca8260e227119129eb76c50c8 221 Gene3D G3DSA:1.10.3130.10 1 66 3.2E-27 T 11-10-2018 AFK25_00495 7e9cc26ca8260e227119129eb76c50c8 221 Pfam PF06426 Serine acetyltransferase, N-terminal 3 35 1.5E-4 T 11-10-2018 IPR010493 Serine acetyltransferase, N-terminal GO:0005737|GO:0006535|GO:0009001 KEGG: 00270+2.3.1.30|KEGG: 00920+2.3.1.30|KEGG: 00999+2.3.1.30|MetaCyc: PWY-6936|MetaCyc: PWY-7274|MetaCyc: PWY-7870 AFK25_00495 7e9cc26ca8260e227119129eb76c50c8 221 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 117 151 3.8E-9 T 11-10-2018 IPR001451 Hexapeptide repeat AFK25_00495 7e9cc26ca8260e227119129eb76c50c8 221 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 71 108 1.1E-5 T 11-10-2018 IPR001451 Hexapeptide repeat AFK25_11970 51c5765fff8ee435353be032219f3ffd 257 SUPERFAMILY SSF56112 2 224 1.78E-31 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily AFK25_11970 51c5765fff8ee435353be032219f3ffd 257 Pfam PF01636 Phosphotransferase enzyme family 14 223 2.3E-25 T 11-10-2018 IPR002575 Aminoglycoside phosphotransferase AFK25_11970 51c5765fff8ee435353be032219f3ffd 257 Gene3D G3DSA:3.90.1200.10 73 254 3.4E-24 T 11-10-2018 AFK25_01320 a34c5a466505c92e9383cdf8965b5de9 475 PIRSF PIRSF000485 8 471 3.0E-186 T 11-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AFK25_01320 a34c5a466505c92e9383cdf8965b5de9 475 SUPERFAMILY SSF53271 246 463 5.77E-76 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like AFK25_01320 a34c5a466505c92e9383cdf8965b5de9 475 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 12 456 6.4E-168 T 11-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AFK25_01320 a34c5a466505c92e9383cdf8965b5de9 475 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 11 455 47.021 T 11-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AFK25_01320 a34c5a466505c92e9383cdf8965b5de9 475 SUPERFAMILY SSF56235 12 252 9.44E-69 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFK25_01320 a34c5a466505c92e9383cdf8965b5de9 475 Gene3D G3DSA:3.60.20.10 12 457 2.9E-169 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFK25_01320 a34c5a466505c92e9383cdf8965b5de9 475 Pfam PF00156 Phosphoribosyl transferase domain 274 381 1.0E-8 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFK25_01320 a34c5a466505c92e9383cdf8965b5de9 475 Pfam PF13537 Glutamine amidotransferase domain 94 208 1.4E-23 T 11-10-2018 IPR017932 Glutamine amidotransferase type 2 domain AFK25_01320 a34c5a466505c92e9383cdf8965b5de9 475 Gene3D G3DSA:3.40.50.2020 270 434 2.9E-169 T 11-10-2018 AFK25_05870 d79cbffbc34eff4f76f0f8e79348fcba 156 Pfam PF17384 RimP C-terminal SH3 domain 86 153 1.2E-22 T 11-10-2018 IPR028998 Ribosome maturation factor RimP, C-terminal AFK25_05870 d79cbffbc34eff4f76f0f8e79348fcba 156 Hamap MF_01077 Ribosome maturation factor RimP [rimP]. 6 155 25.76 T 11-10-2018 IPR003728 Ribosome maturation factor RimP GO:0042274 AFK25_05870 d79cbffbc34eff4f76f0f8e79348fcba 156 SUPERFAMILY SSF75420 3 83 7.85E-28 T 11-10-2018 IPR035956 RimP, N-terminal domain superfamily AFK25_05870 d79cbffbc34eff4f76f0f8e79348fcba 156 Gene3D G3DSA:2.30.30.180 87 153 2.1E-28 T 11-10-2018 AFK25_05870 d79cbffbc34eff4f76f0f8e79348fcba 156 SUPERFAMILY SSF74942 84 155 7.06E-23 T 11-10-2018 IPR036847 Ribosome maturation factor RimP, C-terminal domain superfamily AFK25_05870 d79cbffbc34eff4f76f0f8e79348fcba 156 Pfam PF02576 RimP N-terminal domain 11 83 3.8E-29 T 11-10-2018 IPR028989 Ribosome maturation factor RimP, N-terminal AFK25_05870 d79cbffbc34eff4f76f0f8e79348fcba 156 Gene3D G3DSA:3.30.300.70 1 80 1.4E-30 T 11-10-2018 IPR035956 RimP, N-terminal domain superfamily AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 44 59 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 TIGRFAM TIGR01394 TypA_BipA: GTP-binding protein TypA/BipA 5 599 1.7E-291 T 11-10-2018 IPR006298 GTP-binding protein TypA GO:0005525 AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 SUPERFAMILY SSF52540 3 207 4.57E-56 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 SMART SM00838 395 480 3.5E-7 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 Pfam PF14492 Elongation Factor G, domain II 327 380 9.0E-7 T 11-10-2018 AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 Pfam PF00679 Elongation factor G C-terminus 396 475 6.2E-26 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 SUPERFAMILY SSF50447 151 299 8.25E-33 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 Gene3D G3DSA:3.30.70.240 389 482 1.5E-131 T 11-10-2018 AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 SUPERFAMILY SSF54980 302 387 6.12E-16 T 11-10-2018 IPR035647 EF-G domain III/V-like AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 Gene3D G3DSA:2.40.50.250 483 599 1.5E-131 T 11-10-2018 AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 Pfam PF00009 Elongation factor Tu GTP binding domain 4 195 5.8E-56 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 SUPERFAMILY SSF54980 398 513 1.97E-30 T 11-10-2018 IPR035647 EF-G domain III/V-like AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 5 141 2.6E-22 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 Gene3D G3DSA:2.40.30.10 200 299 4.2E-33 T 11-10-2018 AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 Pfam PF03144 Elongation factor Tu domain 2 219 289 5.9E-12 T 11-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 Gene3D G3DSA:3.30.70.870 306 590 1.5E-131 T 11-10-2018 AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 PRINTS PR00315 GTP-binding elongation factor signature 7 20 7.1E-13 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 PRINTS PR00315 GTP-binding elongation factor signature 71 81 7.1E-13 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 PRINTS PR00315 GTP-binding elongation factor signature 123 132 7.1E-13 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 PRINTS PR00315 GTP-binding elongation factor signature 51 59 7.1E-13 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_04945 c5d9bedb16c37f0c378ba1e69ca5a846 611 Gene3D G3DSA:3.40.50.300 2 198 7.1E-67 T 11-10-2018 AFK25_06770 54c401c918f100f5504d194178e8e162 526 Pfam PF01938 TRAM domain 458 519 1.0E-15 T 11-10-2018 IPR002792 TRAM domain AFK25_06770 54c401c918f100f5504d194178e8e162 526 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 232 252 - T 11-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 AFK25_06770 54c401c918f100f5504d194178e8e162 526 SMART SM00729 228 446 3.0E-70 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFK25_06770 54c401c918f100f5504d194178e8e162 526 Pfam PF00919 Uncharacterized protein family UPF0004 84 185 2.4E-29 T 11-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 AFK25_06770 54c401c918f100f5504d194178e8e162 526 SUPERFAMILY SSF102114 215 451 5.62E-66 T 11-10-2018 AFK25_06770 54c401c918f100f5504d194178e8e162 526 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 84 516 1.9E-166 T 11-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 AFK25_06770 54c401c918f100f5504d194178e8e162 526 Gene3D G3DSA:3.80.30.20 227 460 2.0E-94 T 11-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFK25_06770 54c401c918f100f5504d194178e8e162 526 Pfam PF04055 Radical SAM superfamily 232 403 1.2E-35 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFK25_06770 54c401c918f100f5504d194178e8e162 526 Gene3D G3DSA:3.40.50.12160 83 218 3.8E-35 T 11-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily AFK25_06770 54c401c918f100f5504d194178e8e162 526 TIGRFAM TIGR01574 miaB-methiolase: tRNA-i(6)A37 thiotransferase enzyme MiaB 84 519 1.5E-214 T 11-10-2018 AFK25_06770 54c401c918f100f5504d194178e8e162 526 Hamap MF_01864 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase [miaB]. 83 520 76.29 T 11-10-2018 IPR006463 tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB GO:0005737|GO:0006400|GO:0016740|GO:0051539 AFK25_13740 761a513e7792075dd5ee940262dca102 334 SUPERFAMILY SSF53067 143 326 5.37E-50 T 11-10-2018 AFK25_13740 761a513e7792075dd5ee940262dca102 334 Gene3D G3DSA:3.30.420.40 147 310 2.7E-130 T 11-10-2018 AFK25_13740 761a513e7792075dd5ee940262dca102 334 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 4 327 6.9E-138 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFK25_13740 761a513e7792075dd5ee940262dca102 334 Pfam PF06723 MreB/Mbl protein 5 327 2.2E-152 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFK25_13740 761a513e7792075dd5ee940262dca102 334 Gene3D G3DSA:3.30.420.40 7 319 2.7E-130 T 11-10-2018 AFK25_13740 761a513e7792075dd5ee940262dca102 334 SUPERFAMILY SSF53067 5 141 3.89E-39 T 11-10-2018 AFK25_13740 761a513e7792075dd5ee940262dca102 334 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 42 60 1.2E-58 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFK25_13740 761a513e7792075dd5ee940262dca102 334 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 62 85 1.2E-58 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFK25_13740 761a513e7792075dd5ee940262dca102 334 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 293 319 1.2E-58 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFK25_13740 761a513e7792075dd5ee940262dca102 334 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 180 200 1.2E-58 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFK25_13740 761a513e7792075dd5ee940262dca102 334 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 125 144 1.2E-58 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFK25_13740 761a513e7792075dd5ee940262dca102 334 Gene3D G3DSA:3.90.640.10 179 252 2.7E-130 T 11-10-2018 AFK25_07105 80d33e72de62d032b7fe60d363c0db2b 353 SUPERFAMILY SSF56770 47 307 6.28E-86 T 11-10-2018 AFK25_07105 80d33e72de62d032b7fe60d363c0db2b 353 Gene3D G3DSA:3.40.50.700 45 223 1.3E-66 T 11-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily AFK25_07105 80d33e72de62d032b7fe60d363c0db2b 353 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 61 204 2.1E-29 T 11-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_07105 80d33e72de62d032b7fe60d363c0db2b 353 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 16 33 2.6E-5 T 11-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal AFK25_07105 80d33e72de62d032b7fe60d363c0db2b 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 211 228 5.9E-84 T 11-10-2018 AFK25_07105 80d33e72de62d032b7fe60d363c0db2b 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 46 68 5.9E-84 T 11-10-2018 AFK25_07105 80d33e72de62d032b7fe60d363c0db2b 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 229 247 5.9E-84 T 11-10-2018 AFK25_07105 80d33e72de62d032b7fe60d363c0db2b 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 253 279 5.9E-84 T 11-10-2018 AFK25_07105 80d33e72de62d032b7fe60d363c0db2b 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 115 138 5.9E-84 T 11-10-2018 AFK25_07105 80d33e72de62d032b7fe60d363c0db2b 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 185 208 5.9E-84 T 11-10-2018 AFK25_07105 80d33e72de62d032b7fe60d363c0db2b 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 69 93 5.9E-84 T 11-10-2018 AFK25_07105 80d33e72de62d032b7fe60d363c0db2b 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 156 180 5.9E-84 T 11-10-2018 AFK25_07105 80d33e72de62d032b7fe60d363c0db2b 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 281 294 5.9E-84 T 11-10-2018 AFK25_07105 80d33e72de62d032b7fe60d363c0db2b 353 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 224 305 1.5E-32 T 11-10-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal AFK25_07105 80d33e72de62d032b7fe60d363c0db2b 353 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 3 351 7.5E-140 T 11-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 AFK25_07105 80d33e72de62d032b7fe60d363c0db2b 353 PIRSF PIRSF000310 4 353 6.5E-137 T 11-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 AFK25_07105 80d33e72de62d032b7fe60d363c0db2b 353 Gene3D G3DSA:4.10.480.10 226 336 1.9E-44 T 11-10-2018 IPR037148 [NiFe]-hydrogenase, small subunit, C-terminal domain superfamily AFK25_03280 44a7bc8935c37b9cf8ee0d6e27b5d376 359 Gene3D G3DSA:3.30.420.180 226 358 4.2E-42 T 11-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 AFK25_03280 44a7bc8935c37b9cf8ee0d6e27b5d376 359 Pfam PF11760 Cobalamin synthesis G N-terminal 54 133 3.3E-35 T 11-10-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 AFK25_03280 44a7bc8935c37b9cf8ee0d6e27b5d376 359 SUPERFAMILY SSF159664 229 355 7.59E-40 T 11-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 AFK25_03280 44a7bc8935c37b9cf8ee0d6e27b5d376 359 Pfam PF01890 Cobalamin synthesis G C-terminus 236 353 3.5E-36 T 11-10-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 AFK25_03280 44a7bc8935c37b9cf8ee0d6e27b5d376 359 SUPERFAMILY SSF159672 2 243 3.92E-61 T 11-10-2018 IPR038029 GbiG N-terminal domain superfamily KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 AFK25_03280 44a7bc8935c37b9cf8ee0d6e27b5d376 359 Gene3D G3DSA:3.40.50.11220 1 128 7.6E-33 T 11-10-2018 AFK25_03280 44a7bc8935c37b9cf8ee0d6e27b5d376 359 Pfam PF11761 Cobalamin biosynthesis central region 138 233 7.9E-14 T 11-10-2018 IPR021745 Cobalamin biosynthesis central region KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 AFK25_10330 676598abd95a15dd3b63ad9ab3c98796 94 TIGRFAM TIGR02856 spore_yqfC: sporulation protein YqfC 9 92 3.9E-35 T 11-10-2018 IPR022477 Sporulation protein YqfC AFK25_10330 676598abd95a15dd3b63ad9ab3c98796 94 Pfam PF07873 YabP family 28 91 7.0E-17 T 11-10-2018 IPR022476 Sporulation protein YabP/YqfC AFK25_05350 27d8665560d74851bc02a97dad4f30a2 364 SMART SM01097 1 131 6.2E-93 T 11-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05350 27d8665560d74851bc02a97dad4f30a2 364 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 4 353 2.3E-148 T 11-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05350 27d8665560d74851bc02a97dad4f30a2 364 SUPERFAMILY SSF52317 151 355 2.02E-56 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_05350 27d8665560d74851bc02a97dad4f30a2 364 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 356 49.177 T 11-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05350 27d8665560d74851bc02a97dad4f30a2 364 Gene3D G3DSA:3.40.50.880 170 350 1.9E-34 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_05350 27d8665560d74851bc02a97dad4f30a2 364 Gene3D G3DSA:3.50.30.20 1 147 9.0E-60 T 11-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05350 27d8665560d74851bc02a97dad4f30a2 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 214 223 9.8E-12 T 11-10-2018 AFK25_05350 27d8665560d74851bc02a97dad4f30a2 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 241 252 9.8E-12 T 11-10-2018 AFK25_05350 27d8665560d74851bc02a97dad4f30a2 364 PRINTS PR00096 Glutamine amidotransferase superfamily signature 327 340 9.8E-12 T 11-10-2018 AFK25_05350 27d8665560d74851bc02a97dad4f30a2 364 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 130 2.5E-54 T 11-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05350 27d8665560d74851bc02a97dad4f30a2 364 SUPERFAMILY SSF52021 1 144 7.85E-59 T 11-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_05350 27d8665560d74851bc02a97dad4f30a2 364 PRINTS PR00097 Anthranilate synthase component II signature 214 223 1.7E-6 T 11-10-2018 AFK25_05350 27d8665560d74851bc02a97dad4f30a2 364 PRINTS PR00097 Anthranilate synthase component II signature 241 252 1.7E-6 T 11-10-2018 AFK25_05350 27d8665560d74851bc02a97dad4f30a2 364 PRINTS PR00097 Anthranilate synthase component II signature 327 340 1.7E-6 T 11-10-2018 AFK25_05350 27d8665560d74851bc02a97dad4f30a2 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 241 257 4.9E-37 T 11-10-2018 AFK25_05350 27d8665560d74851bc02a97dad4f30a2 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 172 186 4.9E-37 T 11-10-2018 AFK25_05350 27d8665560d74851bc02a97dad4f30a2 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 211 225 4.9E-37 T 11-10-2018 AFK25_05350 27d8665560d74851bc02a97dad4f30a2 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 258 275 4.9E-37 T 11-10-2018 AFK25_05350 27d8665560d74851bc02a97dad4f30a2 364 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 283 294 4.9E-37 T 11-10-2018 AFK25_05350 27d8665560d74851bc02a97dad4f30a2 364 Pfam PF00117 Glutamine amidotransferase class-I 173 350 4.6E-46 T 11-10-2018 IPR017926 Glutamine amidotransferase AFK25_14480 fbc79c28ef1b8f1b94074d437b958a3f 482 Pfam PF03050 Transposase IS66 family 177 443 1.0E-60 T 11-10-2018 IPR004291 Transposase, IS66 AFK25_14480 fbc79c28ef1b8f1b94074d437b958a3f 482 Pfam PF08961 Nuclear receptor-binding factor 2, autophagy regulator 16 56 5.2E-6 T 11-10-2018 IPR015056 Nuclear receptor-binding factor 2, C-terminal GO:0006914 Reactome: R-HSA-383280 AFK25_14480 fbc79c28ef1b8f1b94074d437b958a3f 482 Pfam PF13005 zinc-finger binding domain of transposase IS66 117 161 4.6E-12 T 11-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 AFK25_13420 fbc79c28ef1b8f1b94074d437b958a3f 482 Pfam PF03050 Transposase IS66 family 177 443 1.0E-60 T 11-10-2018 IPR004291 Transposase, IS66 AFK25_13420 fbc79c28ef1b8f1b94074d437b958a3f 482 Pfam PF08961 Nuclear receptor-binding factor 2, autophagy regulator 16 56 5.2E-6 T 11-10-2018 IPR015056 Nuclear receptor-binding factor 2, C-terminal GO:0006914 Reactome: R-HSA-383280 AFK25_13420 fbc79c28ef1b8f1b94074d437b958a3f 482 Pfam PF13005 zinc-finger binding domain of transposase IS66 117 161 4.6E-12 T 11-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 AFK25_13695 fbc79c28ef1b8f1b94074d437b958a3f 482 Pfam PF03050 Transposase IS66 family 177 443 1.0E-60 T 11-10-2018 IPR004291 Transposase, IS66 AFK25_13695 fbc79c28ef1b8f1b94074d437b958a3f 482 Pfam PF08961 Nuclear receptor-binding factor 2, autophagy regulator 16 56 5.2E-6 T 11-10-2018 IPR015056 Nuclear receptor-binding factor 2, C-terminal GO:0006914 Reactome: R-HSA-383280 AFK25_13695 fbc79c28ef1b8f1b94074d437b958a3f 482 Pfam PF13005 zinc-finger binding domain of transposase IS66 117 161 4.6E-12 T 11-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 AFK25_08215 fbc79c28ef1b8f1b94074d437b958a3f 482 Pfam PF03050 Transposase IS66 family 177 443 1.0E-60 T 11-10-2018 IPR004291 Transposase, IS66 AFK25_08215 fbc79c28ef1b8f1b94074d437b958a3f 482 Pfam PF08961 Nuclear receptor-binding factor 2, autophagy regulator 16 56 5.2E-6 T 11-10-2018 IPR015056 Nuclear receptor-binding factor 2, C-terminal GO:0006914 Reactome: R-HSA-383280 AFK25_08215 fbc79c28ef1b8f1b94074d437b958a3f 482 Pfam PF13005 zinc-finger binding domain of transposase IS66 117 161 4.6E-12 T 11-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 AFK25_01750 f3c3d2fc5e949929f51bbc09556ad24d 325 Pfam PF01966 HD domain 129 233 1.1E-9 T 11-10-2018 IPR006674 HD domain AFK25_01750 f3c3d2fc5e949929f51bbc09556ad24d 325 SUPERFAMILY SSF109604 127 269 3.62E-19 T 11-10-2018 AFK25_01750 f3c3d2fc5e949929f51bbc09556ad24d 325 TIGRFAM TIGR00277 HDIG: HDIG domain 129 202 1.3E-7 T 11-10-2018 IPR006675 HDIG domain AFK25_01750 f3c3d2fc5e949929f51bbc09556ad24d 325 Gene3D G3DSA:1.10.3210.10 8 271 6.7E-42 T 11-10-2018 AFK25_14430 1c342ba14e53927ff2a679715a16a486 351 Pfam PF00005 ABC transporter 23 165 2.6E-36 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_14430 1c342ba14e53927ff2a679715a16a486 351 SMART SM00382 32 215 4.9E-20 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_14430 1c342ba14e53927ff2a679715a16a486 351 TIGRFAM TIGR01187 potA: polyamine ABC transporter, ATP-binding protein 38 290 4.6E-111 T 11-10-2018 IPR005893 Spermidine/putrescine ABC transporter, ATP-binding subunit GO:0015417|GO:0015846|GO:0043190 AFK25_14430 1c342ba14e53927ff2a679715a16a486 351 Gene3D G3DSA:3.40.50.300 6 225 2.4E-71 T 11-10-2018 AFK25_14430 1c342ba14e53927ff2a679715a16a486 351 Gene3D G3DSA:2.40.50.140 283 337 1.9E-12 T 11-10-2018 AFK25_14430 1c342ba14e53927ff2a679715a16a486 351 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_14430 1c342ba14e53927ff2a679715a16a486 351 SUPERFAMILY SSF52540 6 248 4.37E-87 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_14430 1c342ba14e53927ff2a679715a16a486 351 SUPERFAMILY SSF50331 240 346 1.56E-13 T 11-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal AFK25_14430 1c342ba14e53927ff2a679715a16a486 351 Pfam PF08402 TOBE domain 277 345 4.0E-8 T 11-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 AFK25_14430 1c342ba14e53927ff2a679715a16a486 351 Gene3D G3DSA:2.40.50.940 226 344 1.9E-12 T 11-10-2018 AFK25_10490 228a85d7d62e8e123a17f88d2552ff3d 367 SUPERFAMILY SSF52540 68 280 8.62E-33 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_10490 228a85d7d62e8e123a17f88d2552ff3d 367 Gene3D G3DSA:3.40.50.300 57 225 1.9E-51 T 11-10-2018 AFK25_10490 228a85d7d62e8e123a17f88d2552ff3d 367 TIGRFAM TIGR03597 GTPase_YqeH: ribosome biogenesis GTPase YqeH 7 367 2.8E-161 T 11-10-2018 IPR019988 GTP-binding protein, riobosome biogenesis, YqeH AFK25_10490 228a85d7d62e8e123a17f88d2552ff3d 367 Pfam PF01926 50S ribosome-binding GTPase 163 225 4.3E-13 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_05025 8401022161f1007a0f085b12f8d2446c 622 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 25 468 2.2E-149 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05025 8401022161f1007a0f085b12f8d2446c 622 Gene3D G3DSA:1.20.210.10 2 528 1.5E-205 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05025 8401022161f1007a0f085b12f8d2446c 622 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 244 298 - T 11-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05025 8401022161f1007a0f085b12f8d2446c 622 TIGRFAM TIGR02891 CtaD_CoxA: cytochrome c oxidase, subunit I 17 520 7.5E-209 T 11-10-2018 IPR014241 Cytochrome c oxidase, subunit I bacterial type GO:0004129|GO:0005886|GO:0015990|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 AFK25_05025 8401022161f1007a0f085b12f8d2446c 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 312 333 4.1E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05025 8401022161f1007a0f085b12f8d2446c 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 16 41 4.1E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05025 8401022161f1007a0f085b12f8d2446c 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 63 86 4.1E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05025 8401022161f1007a0f085b12f8d2446c 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 132 144 4.1E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05025 8401022161f1007a0f085b12f8d2446c 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 162 180 4.1E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05025 8401022161f1007a0f085b12f8d2446c 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 288 303 4.1E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05025 8401022161f1007a0f085b12f8d2446c 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 347 365 4.1E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05025 8401022161f1007a0f085b12f8d2446c 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 242 263 4.1E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05025 8401022161f1007a0f085b12f8d2446c 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 191 210 4.1E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05025 8401022161f1007a0f085b12f8d2446c 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 425 446 4.1E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05025 8401022161f1007a0f085b12f8d2446c 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 375 394 4.1E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05025 8401022161f1007a0f085b12f8d2446c 622 PRINTS PR01165 Cytochrome c oxidase subunit I signature 90 114 4.1E-103 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05025 8401022161f1007a0f085b12f8d2446c 622 SUPERFAMILY SSF81442 20 548 1.31E-179 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_12295 53cec7877c61d9d6b2fd3f2d090db7a8 795 ProSitePatterns PS00102 Phosphorylase pyridoxal-phosphate attachment site. 638 650 - T 11-10-2018 IPR035090 Phosphorylase pyridoxal-phosphate attachment site KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 AFK25_12295 53cec7877c61d9d6b2fd3f2d090db7a8 795 Gene3D G3DSA:3.40.50.2000 15 794 0.0 T 11-10-2018 AFK25_12295 53cec7877c61d9d6b2fd3f2d090db7a8 795 PIRSF PIRSF000460 2 795 4.7E-235 T 11-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 AFK25_12295 53cec7877c61d9d6b2fd3f2d090db7a8 795 Gene3D G3DSA:3.40.50.2000 460 787 0.0 T 11-10-2018 AFK25_12295 53cec7877c61d9d6b2fd3f2d090db7a8 795 Pfam PF00343 Carbohydrate phosphorylase 93 794 0.0 T 11-10-2018 IPR000811 Glycosyl transferase, family 35 GO:0005975|GO:0008184 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 AFK25_12295 53cec7877c61d9d6b2fd3f2d090db7a8 795 TIGRFAM TIGR02093 P_ylase: glycogen/starch/alpha-glucan phosphorylases 4 794 0.0 T 11-10-2018 IPR011833 Glycogen/starch/alpha-glucan phosphorylase GO:0004645|GO:0005975|GO:0030170 KEGG: 00500+2.4.1.1|MetaCyc: PWY-5941|MetaCyc: PWY-6731|MetaCyc: PWY-6737|MetaCyc: PWY-7238|Reactome: R-HSA-70221 AFK25_12295 53cec7877c61d9d6b2fd3f2d090db7a8 795 SUPERFAMILY SSF53756 3 794 0.0 T 11-10-2018 AFK25_12975 f8936e6292643c9cb35ddb3ea17abf57 480 Gene3D G3DSA:1.25.40.10 152 233 6.9E-15 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_12975 f8936e6292643c9cb35ddb3ea17abf57 480 SUPERFAMILY SSF48452 17 127 1.19E-17 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_12975 f8936e6292643c9cb35ddb3ea17abf57 480 SMART SM00028 148 181 3.6 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_12975 f8936e6292643c9cb35ddb3ea17abf57 480 SMART SM00028 182 215 0.0052 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_12975 f8936e6292643c9cb35ddb3ea17abf57 480 SMART SM00028 19 52 0.021 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_12975 f8936e6292643c9cb35ddb3ea17abf57 480 SMART SM00028 87 120 48.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_12975 f8936e6292643c9cb35ddb3ea17abf57 480 SMART SM00028 53 86 130.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_12975 f8936e6292643c9cb35ddb3ea17abf57 480 SUPERFAMILY SSF48452 153 317 2.98E-23 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_12975 f8936e6292643c9cb35ddb3ea17abf57 480 Gene3D G3DSA:1.25.40.10 234 356 2.0E-6 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_12975 f8936e6292643c9cb35ddb3ea17abf57 480 Pfam PF13181 Tetratricopeptide repeat 21 51 0.0076 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_12975 f8936e6292643c9cb35ddb3ea17abf57 480 Pfam PF14559 Tetratricopeptide repeat 158 216 5.2E-11 T 11-10-2018 AFK25_12975 f8936e6292643c9cb35ddb3ea17abf57 480 Gene3D G3DSA:1.25.40.10 15 147 2.0E-17 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_04625 8546674203138b6555fbf2e7abc89942 254 Gene3D G3DSA:3.40.50.1820 6 254 7.9E-47 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold AFK25_04625 8546674203138b6555fbf2e7abc89942 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 200 214 4.4E-9 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFK25_04625 8546674203138b6555fbf2e7abc89942 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 46 61 4.4E-9 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFK25_04625 8546674203138b6555fbf2e7abc89942 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 104 117 4.4E-9 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFK25_04625 8546674203138b6555fbf2e7abc89942 254 PRINTS PR00111 Alpha/beta hydrolase fold signature 90 103 4.4E-9 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFK25_04625 8546674203138b6555fbf2e7abc89942 254 Pfam PF12146 Serine aminopeptidase, S33 43 237 4.7E-19 T 11-10-2018 IPR022742 Serine aminopeptidase, S33 AFK25_04625 8546674203138b6555fbf2e7abc89942 254 SUPERFAMILY SSF53474 9 252 4.69E-48 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold AFK25_12035 addd97ef47b88a0c07abe69660f67717 421 Pfam PF03486 HI0933-like protein 3 413 2.6E-151 T 11-10-2018 AFK25_12035 addd97ef47b88a0c07abe69660f67717 421 Gene3D G3DSA:3.50.50.60 6 409 5.1E-120 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_12035 addd97ef47b88a0c07abe69660f67717 421 SUPERFAMILY SSF160996 193 361 3.92E-43 T 11-10-2018 AFK25_12035 addd97ef47b88a0c07abe69660f67717 421 TIGRFAM TIGR00275 TIGR00275: flavoprotein, HI0933 family 5 413 3.4E-143 T 11-10-2018 IPR004792 Conserved hypothetical protein CHP00275, flavoprotein HI0933-like AFK25_12035 addd97ef47b88a0c07abe69660f67717 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 1.4E-5 T 11-10-2018 AFK25_12035 addd97ef47b88a0c07abe69660f67717 421 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 1.4E-5 T 11-10-2018 AFK25_12035 addd97ef47b88a0c07abe69660f67717 421 Gene3D G3DSA:1.10.8.260 277 343 5.1E-120 T 11-10-2018 IPR023166 HI0933-like insert domain superfamily AFK25_12035 addd97ef47b88a0c07abe69660f67717 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 2.6E-8 T 11-10-2018 AFK25_12035 addd97ef47b88a0c07abe69660f67717 421 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 159 168 2.6E-8 T 11-10-2018 AFK25_12035 addd97ef47b88a0c07abe69660f67717 421 SUPERFAMILY SSF51905 1 416 6.5E-65 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_12035 addd97ef47b88a0c07abe69660f67717 421 Gene3D G3DSA:2.40.30.10 192 360 5.1E-120 T 11-10-2018 AFK25_00760 4cee5f428e11ee79b93d5b490d8dacc4 265 Hamap MF_01461 Energy-coupling factor transporter transmembrane protein EcfT [ecfT]. 2 265 36.251 T 11-10-2018 IPR024919 ECF transporter transmembrane protein EcfT GO:0016021|GO:0022857|GO:0055085 AFK25_00760 4cee5f428e11ee79b93d5b490d8dacc4 265 Pfam PF02361 Cobalt transport protein 14 237 3.1E-60 T 11-10-2018 IPR003339 ABC/ECF transporter, transmembrane component AFK25_04265 ad44c57e3dedeea08c64c7b0bfe27a62 470 Gene3D G3DSA:1.10.45.10 418 458 6.1E-13 T 11-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 AFK25_04265 ad44c57e3dedeea08c64c7b0bfe27a62 470 Gene3D G3DSA:3.30.465.40 4 237 7.1E-81 T 11-10-2018 AFK25_04265 ad44c57e3dedeea08c64c7b0bfe27a62 470 TIGRFAM TIGR00387 glcD: glycolate oxidase, subunit GlcD 44 456 1.4E-183 T 11-10-2018 IPR004490 Glycolate oxidase subunit GlcD GO:0008891|GO:0009339 AFK25_04265 ad44c57e3dedeea08c64c7b0bfe27a62 470 Gene3D G3DSA:3.30.70.2740 336 417 8.6E-14 T 11-10-2018 AFK25_04265 ad44c57e3dedeea08c64c7b0bfe27a62 470 SUPERFAMILY SSF55103 220 459 1.96E-69 T 11-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AFK25_04265 ad44c57e3dedeea08c64c7b0bfe27a62 470 Pfam PF02913 FAD linked oxidases, C-terminal domain 217 457 1.1E-73 T 11-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AFK25_04265 ad44c57e3dedeea08c64c7b0bfe27a62 470 SUPERFAMILY SSF56176 5 217 7.01E-76 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFK25_04265 ad44c57e3dedeea08c64c7b0bfe27a62 470 Pfam PF01565 FAD binding domain 41 180 1.7E-44 T 11-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFK25_04410 83c3ce916833f47803f74f8bfedcbffe 202 Hamap MF_01677 Methylthioribulose-1-phosphate dehydratase [mtnB]. 1 202 106.188 T 11-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 AFK25_04410 83c3ce916833f47803f74f8bfedcbffe 202 SMART SM01007 7 195 2.1E-44 T 11-10-2018 IPR001303 Class II aldolase/adducin N-terminal AFK25_04410 83c3ce916833f47803f74f8bfedcbffe 202 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 7 193 8.1E-40 T 11-10-2018 IPR001303 Class II aldolase/adducin N-terminal AFK25_04410 83c3ce916833f47803f74f8bfedcbffe 202 Gene3D G3DSA:3.40.225.10 2 202 7.2E-49 T 11-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily AFK25_04410 83c3ce916833f47803f74f8bfedcbffe 202 SUPERFAMILY SSF53639 2 200 5.3E-47 T 11-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily AFK25_04410 83c3ce916833f47803f74f8bfedcbffe 202 TIGRFAM TIGR03328 salvage_mtnB: methylthioribulose-1-phosphate dehydratase 9 198 4.0E-61 T 11-10-2018 IPR017714 Methylthioribulose-1-phosphate dehydratase GO:0005737|GO:0019509|GO:0046872 KEGG: 00270+4.2.1.109|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 AFK25_13785 46452a80e991003fd929eb73f5004d8d 618 TIGRFAM TIGR01974 NDH_I_L: proton-translocating NADH-quinone oxidoreductase, chain L 6 610 2.7E-200 T 11-10-2018 IPR003945 NADH-plastoquinone oxidoreductase, chain 5 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13785 46452a80e991003fd929eb73f5004d8d 618 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 107 127 1.5E-58 T 11-10-2018 AFK25_13785 46452a80e991003fd929eb73f5004d8d 618 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 79 104 1.5E-58 T 11-10-2018 AFK25_13785 46452a80e991003fd929eb73f5004d8d 618 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 221 242 1.5E-58 T 11-10-2018 AFK25_13785 46452a80e991003fd929eb73f5004d8d 618 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 154 175 1.5E-58 T 11-10-2018 AFK25_13785 46452a80e991003fd929eb73f5004d8d 618 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 243 269 1.5E-58 T 11-10-2018 AFK25_13785 46452a80e991003fd929eb73f5004d8d 618 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 311 323 1.5E-58 T 11-10-2018 AFK25_13785 46452a80e991003fd929eb73f5004d8d 618 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 412 431 1.5E-58 T 11-10-2018 AFK25_13785 46452a80e991003fd929eb73f5004d8d 618 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 62 117 7.2E-20 T 11-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13785 46452a80e991003fd929eb73f5004d8d 618 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 55 79 2.6E-11 T 11-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFK25_13785 46452a80e991003fd929eb73f5004d8d 618 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 81 101 2.6E-11 T 11-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFK25_13785 46452a80e991003fd929eb73f5004d8d 618 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 353 375 2.6E-11 T 11-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFK25_13785 46452a80e991003fd929eb73f5004d8d 618 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 411 433 2.6E-11 T 11-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFK25_13785 46452a80e991003fd929eb73f5004d8d 618 Pfam PF00361 Proton-conducting membrane transporter 130 419 2.7E-87 T 11-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_08840 58322f50513b8e1209e64f7b4dea00ff 224 PIRSF PIRSF000032 2 224 3.1E-103 T 11-10-2018 AFK25_08840 58322f50513b8e1209e64f7b4dea00ff 224 Pfam PF00033 Cytochrome b/b6/petB 40 219 4.0E-50 T 11-10-2018 IPR005797 Cytochrome b/b6, N-terminal GO:0009055|GO:0016020|GO:0016491 Reactome: R-HSA-611105 AFK25_08840 58322f50513b8e1209e64f7b4dea00ff 224 SUPERFAMILY SSF81342 6 224 8.63E-62 T 11-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AFK25_08840 58322f50513b8e1209e64f7b4dea00ff 224 Gene3D G3DSA:1.20.810.10 1 224 1.7E-89 T 11-10-2018 IPR027387 Cytochrome b/b6-like domain superfamily Reactome: R-HSA-611105 AFK25_13025 331879778b123070f50f9332a5fa3a45 218 Pfam PF13419 Haloacid dehalogenase-like hydrolase 6 181 2.9E-56 T 11-10-2018 AFK25_13025 331879778b123070f50f9332a5fa3a45 218 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 69 181 1.6E-8 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFK25_13025 331879778b123070f50f9332a5fa3a45 218 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 52 175 7.0E-12 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFK25_13025 331879778b123070f50f9332a5fa3a45 218 Gene3D G3DSA:3.40.50.1000 6 185 6.6E-53 T 11-10-2018 IPR023214 HAD superfamily AFK25_13025 331879778b123070f50f9332a5fa3a45 218 Gene3D G3DSA:1.10.150.240 18 80 6.6E-53 T 11-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 AFK25_13025 331879778b123070f50f9332a5fa3a45 218 Hamap MF_01250 Pyrophosphatase PpaX [ppaX]. 1 214 46.898 T 11-10-2018 IPR023733 Pyrophosphatase PpaX GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFK25_13025 331879778b123070f50f9332a5fa3a45 218 SUPERFAMILY SSF56784 1 210 1.13E-59 T 11-10-2018 IPR036412 HAD-like superfamily AFK25_09420 67bbeecc3edf29889cb7afbed9953f4a 385 SMART SM00936 276 367 2.6E-25 T 11-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFK25_09420 67bbeecc3edf29889cb7afbed9953f4a 385 SUPERFAMILY SSF69189 268 366 8.24E-22 T 11-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFK25_09420 67bbeecc3edf29889cb7afbed9953f4a 385 Gene3D G3DSA:2.60.410.10 276 367 1.7E-23 T 11-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFK25_09420 67bbeecc3edf29889cb7afbed9953f4a 385 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 112 129 5.0E-18 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFK25_09420 67bbeecc3edf29889cb7afbed9953f4a 385 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 139 152 5.0E-18 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFK25_09420 67bbeecc3edf29889cb7afbed9953f4a 385 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 59 70 5.0E-18 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFK25_09420 67bbeecc3edf29889cb7afbed9953f4a 385 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 276 367 3.5E-20 T 11-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFK25_09420 67bbeecc3edf29889cb7afbed9953f4a 385 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 26 256 1.4E-90 T 11-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 AFK25_09420 67bbeecc3edf29889cb7afbed9953f4a 385 SUPERFAMILY SSF56601 1 276 7.89E-83 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFK25_09420 67bbeecc3edf29889cb7afbed9953f4a 385 Gene3D G3DSA:3.40.710.10 17 275 4.4E-94 T 11-10-2018 AFK25_01015 7b0705aff02517650b96e2b1c1354c7c 452 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 3.3E-47 T 11-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFK25_01015 7b0705aff02517650b96e2b1c1354c7c 452 Gene3D G3DSA:3.40.50.20 1 85 2.5E-37 T 11-10-2018 AFK25_01015 7b0705aff02517650b96e2b1c1354c7c 452 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 322 4.9E-84 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_01015 7b0705aff02517650b96e2b1c1354c7c 452 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 445 4.8E-191 T 11-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 AFK25_01015 7b0705aff02517650b96e2b1c1354c7c 452 SUPERFAMILY SSF52440 1 113 7.19E-50 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFK25_01015 7b0705aff02517650b96e2b1c1354c7c 452 SUPERFAMILY SSF51246 331 444 7.85E-41 T 11-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFK25_01015 7b0705aff02517650b96e2b1c1354c7c 452 Pfam PF02785 Biotin carboxylase C-terminal domain 336 441 1.8E-37 T 11-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFK25_01015 7b0705aff02517650b96e2b1c1354c7c 452 Gene3D G3DSA:3.30.470.20 87 440 2.4E-162 T 11-10-2018 AFK25_01015 7b0705aff02517650b96e2b1c1354c7c 452 SUPERFAMILY SSF56059 83 352 1.2E-73 T 11-10-2018 AFK25_01015 7b0705aff02517650b96e2b1c1354c7c 452 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 286 293 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_01015 7b0705aff02517650b96e2b1c1354c7c 452 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_01015 7b0705aff02517650b96e2b1c1354c7c 452 SMART SM00878 336 441 2.7E-54 T 11-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFK25_01015 7b0705aff02517650b96e2b1c1354c7c 452 Gene3D G3DSA:3.30.1490.20 131 202 2.4E-162 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFK25_10430 14b6908bd6f2aca63623645ea6ba2c1a 326 Gene3D G3DSA:1.10.8.60 138 201 1.2E-10 T 11-10-2018 AFK25_10430 14b6908bd6f2aca63623645ea6ba2c1a 326 Gene3D G3DSA:3.40.50.300 2 136 3.6E-38 T 11-10-2018 AFK25_10430 14b6908bd6f2aca63623645ea6ba2c1a 326 TIGRFAM TIGR01128 holA: DNA polymerase III, delta subunit 10 324 3.8E-83 T 11-10-2018 IPR005790 DNA polymerase III, delta subunit GO:0003677|GO:0006260 AFK25_10430 14b6908bd6f2aca63623645ea6ba2c1a 326 SUPERFAMILY SSF48019 205 324 1.19E-25 T 11-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 AFK25_10430 14b6908bd6f2aca63623645ea6ba2c1a 326 SUPERFAMILY SSF52540 9 201 7.53E-26 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_10430 14b6908bd6f2aca63623645ea6ba2c1a 326 Gene3D G3DSA:1.20.272.10 202 326 3.9E-38 T 11-10-2018 AFK25_10430 14b6908bd6f2aca63623645ea6ba2c1a 326 Pfam PF06144 DNA polymerase III, delta subunit 12 183 1.6E-48 T 11-10-2018 IPR010372 DNA polymerase III delta, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0009360 AFK25_13085 29774741a0d87ed4379b2b1445ff9c2b 478 SUPERFAMILY SSF47090 384 455 8.77E-20 T 11-10-2018 IPR036365 PGBD-like superfamily AFK25_13085 29774741a0d87ed4379b2b1445ff9c2b 478 Gene3D G3DSA:2.30.42.10 111 198 2.5E-93 T 11-10-2018 AFK25_13085 29774741a0d87ed4379b2b1445ff9c2b 478 Pfam PF01471 Putative peptidoglycan binding domain 397 452 3.8E-18 T 11-10-2018 IPR002477 Peptidoglycan binding-like AFK25_13085 29774741a0d87ed4379b2b1445ff9c2b 478 SMART SM00245 184 375 6.8E-71 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 AFK25_13085 29774741a0d87ed4379b2b1445ff9c2b 478 TIGRFAM TIGR00225 prc: C-terminal processing peptidase 62 380 1.6E-122 T 11-10-2018 IPR004447 C-terminal-processing peptidase S41A GO:0006508|GO:0008236 AFK25_13085 29774741a0d87ed4379b2b1445ff9c2b 478 Gene3D G3DSA:3.30.750.44 56 350 2.5E-93 T 11-10-2018 AFK25_13085 29774741a0d87ed4379b2b1445ff9c2b 478 Gene3D G3DSA:1.10.101.10 382 462 4.4E-18 T 11-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 AFK25_13085 29774741a0d87ed4379b2b1445ff9c2b 478 Gene3D G3DSA:3.90.226.10 199 372 2.5E-93 T 11-10-2018 AFK25_13085 29774741a0d87ed4379b2b1445ff9c2b 478 SUPERFAMILY SSF52096 43 379 2.82E-73 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFK25_13085 29774741a0d87ed4379b2b1445ff9c2b 478 SUPERFAMILY SSF50156 82 204 2.63E-23 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 AFK25_13085 29774741a0d87ed4379b2b1445ff9c2b 478 Pfam PF13180 PDZ domain 112 185 2.5E-11 T 11-10-2018 IPR001478 PDZ domain GO:0005515 AFK25_13085 29774741a0d87ed4379b2b1445ff9c2b 478 SMART SM00228 111 182 2.1E-18 T 11-10-2018 IPR001478 PDZ domain GO:0005515 AFK25_13085 29774741a0d87ed4379b2b1445ff9c2b 478 Pfam PF03572 Peptidase family S41 213 374 2.3E-51 T 11-10-2018 IPR005151 Tail specific protease GO:0006508|GO:0008236 Reactome: R-HSA-2187335|Reactome: R-HSA-2453902 AFK25_01695 1e3cc2f759ab974b7c918f62135e020c 667 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 25 43 3.7E-5 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_01695 1e3cc2f759ab974b7c918f62135e020c 667 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 3.7E-5 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_01695 1e3cc2f759ab974b7c918f62135e020c 667 Gene3D G3DSA:3.40.50.300 2 168 1.0E-39 T 11-10-2018 AFK25_01695 1e3cc2f759ab974b7c918f62135e020c 667 Pfam PF07664 Ferrous iron transport protein B C terminus 455 507 2.5E-18 T 11-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 AFK25_01695 1e3cc2f759ab974b7c918f62135e020c 667 SUPERFAMILY SSF52540 1 167 2.83E-35 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_01695 1e3cc2f759ab974b7c918f62135e020c 667 Pfam PF02421 Ferrous iron transport protein B 3 152 2.9E-61 T 11-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 AFK25_01695 1e3cc2f759ab974b7c918f62135e020c 667 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 8 633 5.6E-193 T 11-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 AFK25_01695 1e3cc2f759ab974b7c918f62135e020c 667 Pfam PF07670 Nucleoside recognition 512 636 6.2E-32 T 11-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 AFK25_01695 1e3cc2f759ab974b7c918f62135e020c 667 Pfam PF07670 Nucleoside recognition 352 445 6.7E-16 T 11-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 AFK25_02150 914333556cec2c3282f2891178041231 400 SUPERFAMILY SSF53098 115 286 5.5E-21 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_02150 914333556cec2c3282f2891178041231 400 Pfam PF00665 Integrase core domain 116 242 8.9E-27 T 11-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFK25_02150 914333556cec2c3282f2891178041231 400 Gene3D G3DSA:3.30.420.10 113 282 4.0E-10 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFK25_02150 914333556cec2c3282f2891178041231 400 Pfam PF02796 Helix-turn-helix domain of resolvase 10 39 3.3E-6 T 11-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 AFK25_02150 914333556cec2c3282f2891178041231 400 Gene3D G3DSA:1.10.10.60 8 40 1.9E-7 T 11-10-2018 AFK25_10585 914333556cec2c3282f2891178041231 400 SUPERFAMILY SSF53098 115 286 5.5E-21 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_10585 914333556cec2c3282f2891178041231 400 Pfam PF00665 Integrase core domain 116 242 8.9E-27 T 11-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFK25_10585 914333556cec2c3282f2891178041231 400 Gene3D G3DSA:3.30.420.10 113 282 4.0E-10 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFK25_10585 914333556cec2c3282f2891178041231 400 Pfam PF02796 Helix-turn-helix domain of resolvase 10 39 3.3E-6 T 11-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 AFK25_10585 914333556cec2c3282f2891178041231 400 Gene3D G3DSA:1.10.10.60 8 40 1.9E-7 T 11-10-2018 AFK25_11105 872fa70602826c3ba0e832e6460641df 249 SUPERFAMILY SSF69618 4 246 1.96E-63 T 11-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFK25_11105 872fa70602826c3ba0e832e6460641df 249 Gene3D G3DSA:3.40.50.10090 140 244 9.8E-21 T 11-10-2018 AFK25_11105 872fa70602826c3ba0e832e6460641df 249 Gene3D G3DSA:3.40.50.10090 2 125 2.0E-27 T 11-10-2018 AFK25_11105 872fa70602826c3ba0e832e6460641df 249 Pfam PF02602 Uroporphyrinogen-III synthase HemD 18 239 4.0E-59 T 11-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFK25_04285 1a66a4f95733c7693314bce7b12f31d2 780 SUPERFAMILY SSF48208 273 768 1.81E-122 T 11-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFK25_04285 1a66a4f95733c7693314bce7b12f31d2 780 Pfam PF03636 Glycosyl hydrolase family 65, N-terminal domain 18 256 5.9E-57 T 11-10-2018 IPR005196 Glycoside hydrolase, family 65, N-terminal GO:0003824|GO:0005975 AFK25_04285 1a66a4f95733c7693314bce7b12f31d2 780 SUPERFAMILY SSF74650 10 257 2.51E-62 T 11-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 AFK25_04285 1a66a4f95733c7693314bce7b12f31d2 780 Pfam PF03633 Glycosyl hydrolase family 65, C-terminal domain 719 771 7.8E-12 T 11-10-2018 IPR005194 Glycoside hydrolase family 65, C-terminal AFK25_04285 1a66a4f95733c7693314bce7b12f31d2 780 Pfam PF03632 Glycosyl hydrolase family 65 central catalytic domain 320 715 6.8E-135 T 11-10-2018 IPR005195 Glycoside hydrolase, family 65, central catalytic GO:0003824|GO:0005975 AFK25_04285 1a66a4f95733c7693314bce7b12f31d2 780 PIRSF PIRSF036289 7 779 5.2E-236 T 11-10-2018 IPR017045 Maltose phosphorylase/glycosyl hydrolase/vacuolar acid trehalase AFK25_04285 1a66a4f95733c7693314bce7b12f31d2 780 Gene3D G3DSA:2.60.420.10 701 778 1.9E-21 T 11-10-2018 AFK25_04285 1a66a4f95733c7693314bce7b12f31d2 780 Gene3D G3DSA:1.50.10.10 314 700 2.3E-150 T 11-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFK25_04285 1a66a4f95733c7693314bce7b12f31d2 780 Gene3D G3DSA:2.70.98.40 10 259 1.4E-68 T 11-10-2018 IPR037018 Glycoside hydrolase family 65, N-terminal domain superfamily AFK25_01490 4698f1ab4141f11f4c45459ca4e2b73d 145 Gene3D G3DSA:3.30.300.20 2 130 2.7E-39 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta AFK25_01490 4698f1ab4141f11f4c45459ca4e2b73d 145 SUPERFAMILY SSF82784 12 138 5.1E-35 T 11-10-2018 IPR036102 OsmC/Ohr superfamily AFK25_01490 4698f1ab4141f11f4c45459ca4e2b73d 145 Pfam PF02566 OsmC-like protein 36 137 1.7E-19 T 11-10-2018 IPR003718 OsmC/Ohr family AFK25_05890 e9ed60cb144271d35d881b4cfed3aaae 727 Hamap MF_00100_B Translation initiation factor IF-2 [infB]. 3 726 17.863 T 11-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 AFK25_05890 e9ed60cb144271d35d881b4cfed3aaae 727 ProSitePatterns PS01176 Initiation factor 2 signature. 679 701 - T 11-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 AFK25_05890 e9ed60cb144271d35d881b4cfed3aaae 727 Gene3D G3DSA:3.40.50.300 225 399 1.0E-78 T 11-10-2018 AFK25_05890 e9ed60cb144271d35d881b4cfed3aaae 727 TIGRFAM TIGR00487 IF-2: translation initiation factor IF-2 144 726 2.1E-284 T 11-10-2018 IPR000178 Translation initiation factor aIF-2, bacterial-like GO:0003743|GO:0005525|GO:0005622|GO:0006413 Reactome: R-HSA-5368286 AFK25_05890 e9ed60cb144271d35d881b4cfed3aaae 727 SUPERFAMILY SSF50447 400 483 7.86E-28 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFK25_05890 e9ed60cb144271d35d881b4cfed3aaae 727 SUPERFAMILY SSF52156 509 635 3.53E-40 T 11-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily AFK25_05890 e9ed60cb144271d35d881b4cfed3aaae 727 Pfam PF11987 Translation-initiation factor 2 514 618 6.9E-39 T 11-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 AFK25_05890 e9ed60cb144271d35d881b4cfed3aaae 727 SUPERFAMILY SSF52540 219 401 1.56E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_05890 e9ed60cb144271d35d881b4cfed3aaae 727 Gene3D G3DSA:3.40.50.10050 522 629 7.9E-41 T 11-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily AFK25_05890 e9ed60cb144271d35d881b4cfed3aaae 727 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 154 202 5.0E-14 T 11-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal AFK25_05890 e9ed60cb144271d35d881b4cfed3aaae 727 Pfam PF04760 Translation initiation factor IF-2, N-terminal region 1 52 1.6E-14 T 11-10-2018 IPR006847 Translation initiation factor IF-2, N-terminal AFK25_05890 e9ed60cb144271d35d881b4cfed3aaae 727 Gene3D G3DSA:2.40.30.10 400 516 7.4E-44 T 11-10-2018 AFK25_05890 e9ed60cb144271d35d881b4cfed3aaae 727 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 230 387 2.5E-40 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFK25_05890 e9ed60cb144271d35d881b4cfed3aaae 727 Gene3D G3DSA:2.40.30.10 630 727 1.3E-37 T 11-10-2018 AFK25_05890 e9ed60cb144271d35d881b4cfed3aaae 727 SUPERFAMILY SSF50447 629 726 1.04E-35 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFK25_05890 e9ed60cb144271d35d881b4cfed3aaae 727 Gene3D G3DSA:1.10.10.2480 1 69 1.2E-14 T 11-10-2018 AFK25_05890 e9ed60cb144271d35d881b4cfed3aaae 727 Pfam PF00009 Elongation factor Tu GTP binding domain 233 388 2.9E-35 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_01760 5e10fdeb8f2382c7243ab681bce6f8dd 156 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 4 146 8.1E-43 T 11-10-2018 IPR023485 Phosphotyrosine protein phosphatase I AFK25_01760 5e10fdeb8f2382c7243ab681bce6f8dd 156 SUPERFAMILY SSF52788 1 150 1.57E-52 T 11-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily AFK25_01760 5e10fdeb8f2382c7243ab681bce6f8dd 156 SMART SM00226 2 149 2.0E-56 T 11-10-2018 IPR023485 Phosphotyrosine protein phosphatase I AFK25_01760 5e10fdeb8f2382c7243ab681bce6f8dd 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 47 63 7.5E-17 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 AFK25_01760 5e10fdeb8f2382c7243ab681bce6f8dd 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 123 138 7.5E-17 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 AFK25_01760 5e10fdeb8f2382c7243ab681bce6f8dd 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 104 117 7.5E-17 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 AFK25_01760 5e10fdeb8f2382c7243ab681bce6f8dd 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 4 21 7.5E-17 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 AFK25_01760 5e10fdeb8f2382c7243ab681bce6f8dd 156 PRINTS PR00719 LMW phosphotyrosine protein phosphatase signature 81 96 7.5E-17 T 11-10-2018 IPR017867 Protein-tyrosine phosphatase, low molecular weight GO:0004725|GO:0006470 AFK25_01760 5e10fdeb8f2382c7243ab681bce6f8dd 156 Gene3D G3DSA:3.40.50.2300 1 156 5.3E-63 T 11-10-2018 AFK25_10285 75f8591bc033a9784ec1493f84d22c98 603 Pfam PF01807 CHC2 zinc finger 6 98 1.9E-40 T 11-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 AFK25_10285 75f8591bc033a9784ec1493f84d22c98 603 Gene3D G3DSA:3.90.580.10 1 101 6.6E-45 T 11-10-2018 IPR036977 DNA Primase, CHC2-type zinc finger GO:0003677|GO:0006260|GO:0008270 AFK25_10285 75f8591bc033a9784ec1493f84d22c98 603 SUPERFAMILY SSF48024 454 555 7.32E-10 T 11-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 AFK25_10285 75f8591bc033a9784ec1493f84d22c98 603 Pfam PF00772 DnaB-like helicase N terminal domain 459 552 7.2E-6 T 11-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 AFK25_10285 75f8591bc033a9784ec1493f84d22c98 603 Gene3D G3DSA:1.10.860.10 459 555 4.1E-36 T 11-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal AFK25_10285 75f8591bc033a9784ec1493f84d22c98 603 SMART SM00493 260 331 2.4E-17 T 11-10-2018 IPR006171 TOPRIM domain AFK25_10285 75f8591bc033a9784ec1493f84d22c98 603 TIGRFAM TIGR01391 dnaG: DNA primase 4 418 4.3E-156 T 11-10-2018 IPR006295 DNA primase, DnaG GO:0003896|GO:0006269 AFK25_10285 75f8591bc033a9784ec1493f84d22c98 603 Pfam PF10410 DnaB-helicase binding domain of primase 370 421 1.6E-11 T 11-10-2018 IPR019475 DNA primase, DnaB-helicase binding domain GO:0016779 AFK25_10285 75f8591bc033a9784ec1493f84d22c98 603 Gene3D G3DSA:3.40.1360.10 242 366 1.1E-37 T 11-10-2018 AFK25_10285 75f8591bc033a9784ec1493f84d22c98 603 PIRSF PIRSF002811 2 595 3.2E-193 T 11-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 AFK25_10285 75f8591bc033a9784ec1493f84d22c98 603 SUPERFAMILY SSF57783 4 98 4.08E-39 T 11-10-2018 AFK25_10285 75f8591bc033a9784ec1493f84d22c98 603 Gene3D G3DSA:3.90.980.10 111 241 2.0E-48 T 11-10-2018 IPR037068 DNA primase, catalytic core, N-terminal domain superfamily AFK25_10285 75f8591bc033a9784ec1493f84d22c98 603 SUPERFAMILY SSF56731 115 425 3.53E-103 T 11-10-2018 AFK25_10285 75f8591bc033a9784ec1493f84d22c98 603 SMART SM00400 36 90 7.1E-39 T 11-10-2018 IPR002694 Zinc finger, CHC2-type GO:0003677|GO:0003896|GO:0006260|GO:0008270 AFK25_10285 75f8591bc033a9784ec1493f84d22c98 603 Hamap MF_00974 DNA primase [dnaG]. 4 585 30.258 T 11-10-2018 IPR030846 DNA primase DnaG, bacteria GO:0003896|GO:0006269|GO:0008270 AFK25_10285 75f8591bc033a9784ec1493f84d22c98 603 Pfam PF08275 DNA primase catalytic core, N-terminal domain 126 253 9.8E-44 T 11-10-2018 IPR013264 DNA primase, catalytic core, N-terminal AFK25_10285 75f8591bc033a9784ec1493f84d22c98 603 Pfam PF13155 Toprim-like 263 347 1.5E-19 T 11-10-2018 AFK25_05650 42a86e2f6b4ddf7ce0a3a5ad969154c3 126 PIRSF PIRSF002889 2 125 1.3E-31 T 11-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 AFK25_05650 42a86e2f6b4ddf7ce0a3a5ad969154c3 126 Pfam PF00460 Flagella basal body rod protein 9 38 3.8E-8 T 11-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 AFK25_05650 42a86e2f6b4ddf7ce0a3a5ad969154c3 126 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 14 34 - T 11-10-2018 IPR019776 Flagellar basal body rod protein, conserved site AFK25_05650 42a86e2f6b4ddf7ce0a3a5ad969154c3 126 TIGRFAM TIGR01396 FlgB: flagellar basal-body rod protein FlgB 4 123 3.3E-32 T 11-10-2018 IPR006300 Flagellar basal-body rod protein FlgB GO:0030694|GO:0071973 AFK25_11450 bb2c28b9972f60f84408618b19c6b600 353 Gene3D G3DSA:2.70.98.10 8 351 3.7E-124 T 11-10-2018 IPR014718 Glycoside hydrolase-type carbohydrate-binding GO:0030246 AFK25_11450 bb2c28b9972f60f84408618b19c6b600 353 SUPERFAMILY SSF74650 2 345 1.26E-115 T 11-10-2018 IPR011013 Galactose mutarotase-like domain superfamily GO:0003824|GO:0005975|GO:0030246 AFK25_11450 bb2c28b9972f60f84408618b19c6b600 353 Pfam PF01263 Aldose 1-epimerase 19 344 4.5E-96 T 11-10-2018 IPR008183 Aldose 1-/Glucose-6-phosphate 1-epimerase GO:0005975|GO:0016853 AFK25_11450 bb2c28b9972f60f84408618b19c6b600 353 PIRSF PIRSF005096 1 348 3.2E-137 T 11-10-2018 IPR015443 Aldose 1-epimerase GO:0016853|GO:0019318 KEGG: 00010+5.1.3.3|KEGG: 00052+5.1.3.3|MetaCyc: PWY-6317 AFK25_06215 f36c34cd4686009b420cca8e59420c89 215 Gene3D G3DSA:1.10.150.320 118 195 1.6E-9 T 11-10-2018 AFK25_06215 f36c34cd4686009b420cca8e59420c89 215 SUPERFAMILY SSF47781 129 197 9.78E-13 T 11-10-2018 IPR010994 RuvA domain 2-like AFK25_06215 f36c34cd4686009b420cca8e59420c89 215 Pfam PF12836 Helix-hairpin-helix motif 133 194 5.4E-14 T 11-10-2018 AFK25_06520 29ec844e5075b5880fa18caebb2e6cd3 217 Gene3D G3DSA:1.10.3720.10 1 216 1.8E-59 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_06520 29ec844e5075b5880fa18caebb2e6cd3 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 33 214 1.5E-20 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_06520 29ec844e5075b5880fa18caebb2e6cd3 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 108 3.1E-28 T 11-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 AFK25_06520 29ec844e5075b5880fa18caebb2e6cd3 217 SUPERFAMILY SSF161098 11 199 5.36E-48 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_04515 a849452c9edcd8f057ae4f2fb8d35f05 221 Gene3D G3DSA:3.40.50.620 2 220 3.7E-74 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_04515 a849452c9edcd8f057ae4f2fb8d35f05 221 Pfam PF06508 Queuosine biosynthesis protein QueC 5 211 1.7E-84 T 11-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AFK25_04515 a849452c9edcd8f057ae4f2fb8d35f05 221 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 4 217 51.084 T 11-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AFK25_04515 a849452c9edcd8f057ae4f2fb8d35f05 221 PIRSF PIRSF006293 2 221 1.8E-78 T 11-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AFK25_04515 a849452c9edcd8f057ae4f2fb8d35f05 221 SUPERFAMILY SSF52402 4 211 1.48E-67 T 11-10-2018 AFK25_04515 a849452c9edcd8f057ae4f2fb8d35f05 221 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 6 204 8.1E-83 T 11-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AFK25_10780 bc64355607b8edb3d6fc1ff993d82924 786 SUPERFAMILY SSF64182 56 449 2.09E-118 T 11-10-2018 IPR038763 DHH phosphoesterase superfamily AFK25_10780 bc64355607b8edb3d6fc1ff993d82924 786 Pfam PF01368 DHH family 82 209 2.2E-9 T 11-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFK25_10780 bc64355607b8edb3d6fc1ff993d82924 786 Gene3D G3DSA:3.90.1640.30 56 316 1.3E-93 T 11-10-2018 AFK25_10780 bc64355607b8edb3d6fc1ff993d82924 786 Pfam PF02272 DHHA1 domain 315 435 2.7E-20 T 11-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 AFK25_10780 bc64355607b8edb3d6fc1ff993d82924 786 Gene3D G3DSA:3.10.310.30 317 440 2.3E-35 T 11-10-2018 AFK25_10780 bc64355607b8edb3d6fc1ff993d82924 786 TIGRFAM TIGR00644 recJ: single-stranded-DNA-specific exonuclease RecJ 28 558 1.2E-181 T 11-10-2018 IPR004610 Bacterial RecJ exonuclease GO:0006281|GO:0006310|GO:0008409 AFK25_10780 bc64355607b8edb3d6fc1ff993d82924 786 Pfam PF10141 Single-strand DNA-specific exonuclease, C terminal domain 564 766 5.3E-67 T 11-10-2018 IPR018779 Single-stranded-DNA-specific exonuclease RecJ, C-terminal AFK25_10770 c28aa7cd205e0eeea3a5ff69c466e0a3 732 SUPERFAMILY SSF81271 380 452 3.92E-24 T 11-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AFK25_10770 c28aa7cd205e0eeea3a5ff69c466e0a3 732 Gene3D G3DSA:3.10.20.30 386 458 2.2E-33 T 11-10-2018 IPR012675 Beta-grasp domain superfamily AFK25_10770 c28aa7cd205e0eeea3a5ff69c466e0a3 732 SUPERFAMILY SSF81301 185 397 6.87E-69 T 11-10-2018 AFK25_10770 c28aa7cd205e0eeea3a5ff69c466e0a3 732 SUPERFAMILY SSF55021 654 732 1.08E-13 T 11-10-2018 AFK25_10770 c28aa7cd205e0eeea3a5ff69c466e0a3 732 Pfam PF13328 HD domain 31 180 3.8E-54 T 11-10-2018 IPR003607 HD/PDEase domain AFK25_10770 c28aa7cd205e0eeea3a5ff69c466e0a3 732 Pfam PF02824 TGS domain 393 452 9.4E-25 T 11-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 AFK25_10770 c28aa7cd205e0eeea3a5ff69c466e0a3 732 SMART SM00471 46 158 9.5E-10 T 11-10-2018 IPR003607 HD/PDEase domain AFK25_10770 c28aa7cd205e0eeea3a5ff69c466e0a3 732 Pfam PF13291 ACT domain 651 729 3.6E-24 T 11-10-2018 IPR002912 ACT domain AFK25_10770 c28aa7cd205e0eeea3a5ff69c466e0a3 732 SMART SM00954 240 350 1.0E-69 T 11-10-2018 IPR007685 RelA/SpoT GO:0015969 AFK25_10770 c28aa7cd205e0eeea3a5ff69c466e0a3 732 Gene3D G3DSA:3.30.70.260 652 732 6.0E-20 T 11-10-2018 AFK25_10770 c28aa7cd205e0eeea3a5ff69c466e0a3 732 SUPERFAMILY SSF109604 10 196 8.79E-79 T 11-10-2018 AFK25_10770 c28aa7cd205e0eeea3a5ff69c466e0a3 732 Gene3D G3DSA:1.10.3210.10 1 196 2.9E-92 T 11-10-2018 AFK25_10770 c28aa7cd205e0eeea3a5ff69c466e0a3 732 TIGRFAM TIGR00691 spoT_relA: RelA/SpoT family protein 31 729 3.4E-265 T 11-10-2018 IPR004811 RelA/SpoT family GO:0015969 AFK25_10770 c28aa7cd205e0eeea3a5ff69c466e0a3 732 Gene3D G3DSA:3.30.460.10 198 329 3.6E-56 T 11-10-2018 AFK25_10770 c28aa7cd205e0eeea3a5ff69c466e0a3 732 Pfam PF04607 Region found in RelA / SpoT proteins 240 350 7.2E-40 T 11-10-2018 IPR007685 RelA/SpoT GO:0015969 AFK25_01350 fd833cbdf7f4d1ae02f63bbae404aeb1 580 Pfam PF13382 Adenine deaminase C-terminal domain 419 570 1.1E-37 T 11-10-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 AFK25_01350 fd833cbdf7f4d1ae02f63bbae404aeb1 580 SUPERFAMILY SSF51338 22 367 2.33E-13 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFK25_01350 fd833cbdf7f4d1ae02f63bbae404aeb1 580 SUPERFAMILY SSF51556 82 328 5.84E-13 T 11-10-2018 IPR032466 Metal-dependent hydrolase AFK25_01350 fd833cbdf7f4d1ae02f63bbae404aeb1 580 Gene3D G3DSA:2.30.40.10 21 362 1.4E-82 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFK25_01350 fd833cbdf7f4d1ae02f63bbae404aeb1 580 Gene3D G3DSA:3.20.20.140 82 325 1.4E-82 T 11-10-2018 AFK25_01350 fd833cbdf7f4d1ae02f63bbae404aeb1 580 Pfam PF01979 Amidohydrolase family 78 362 4.3E-19 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFK25_09305 73a7e00eeaef4812476b57078d8e5839 77 SUPERFAMILY SSF53383 2 74 1.9E-23 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_09305 73a7e00eeaef4812476b57078d8e5839 77 Gene3D G3DSA:3.40.640.10 1 77 1.0E-22 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_09305 73a7e00eeaef4812476b57078d8e5839 77 Pfam PF01212 Beta-eliminating lyase 3 71 3.9E-20 T 11-10-2018 IPR001597 Aromatic amino acid beta-eliminating lyase/threonine aldolase GO:0006520|GO:0016829 Reactome: R-HSA-6783984 AFK25_09425 a201c72d8b2c9cab42d2ddbce3657963 433 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 110 125 - T 11-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFK25_09425 a201c72d8b2c9cab42d2ddbce3657963 433 SUPERFAMILY SSF52418 69 329 7.06E-94 T 11-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFK25_09425 a201c72d8b2c9cab42d2ddbce3657963 433 Gene3D G3DSA:3.90.1170.30 331 420 7.4E-157 T 11-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFK25_09425 a201c72d8b2c9cab42d2ddbce3657963 433 SUPERFAMILY SSF54680 331 432 2.49E-30 T 11-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFK25_09425 a201c72d8b2c9cab42d2ddbce3657963 433 TIGRFAM TIGR02644 Y_phosphoryl: pyrimidine-nucleoside phosphorylase 3 417 5.3E-185 T 11-10-2018 IPR018090 Pyrimidine-nucleoside phosphorylase, bacterial/eukaryotic GO:0006213|GO:0016154 KEGG: 00240+2.4.2.4|KEGG: 00983+2.4.2.4|MetaCyc: PWY-7181|Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFK25_09425 a201c72d8b2c9cab42d2ddbce3657963 433 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 345 418 1.3E-26 T 11-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFK25_09425 a201c72d8b2c9cab42d2ddbce3657963 433 Gene3D G3DSA:1.20.970.10 1 67 3.3E-32 T 11-10-2018 AFK25_09425 a201c72d8b2c9cab42d2ddbce3657963 433 Pfam PF00591 Glycosyl transferase family, a/b domain 78 306 2.2E-46 T 11-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFK25_09425 a201c72d8b2c9cab42d2ddbce3657963 433 Pfam PF02885 Glycosyl transferase family, helical bundle domain 4 66 2.1E-26 T 11-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFK25_09425 a201c72d8b2c9cab42d2ddbce3657963 433 PIRSF PIRSF000478 1 433 1.6E-171 T 11-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFK25_09425 a201c72d8b2c9cab42d2ddbce3657963 433 Gene3D G3DSA:3.40.1030.10 77 330 7.4E-157 T 11-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFK25_09425 a201c72d8b2c9cab42d2ddbce3657963 433 SUPERFAMILY SSF47648 1 69 1.16E-24 T 11-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFK25_09425 a201c72d8b2c9cab42d2ddbce3657963 433 SMART SM00941 345 418 1.6E-32 T 11-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFK25_02705 4294c648fad497c22cb17f45e0ca527e 373 SUPERFAMILY SSF51905 1 368 7.34E-53 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_02705 4294c648fad497c22cb17f45e0ca527e 373 Pfam PF01266 FAD dependent oxidoreductase 2 347 8.9E-70 T 11-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFK25_02705 4294c648fad497c22cb17f45e0ca527e 373 SUPERFAMILY SSF54373 220 307 3.66E-15 T 11-10-2018 AFK25_02705 4294c648fad497c22cb17f45e0ca527e 373 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 30 42 3.1E-8 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFK25_02705 4294c648fad497c22cb17f45e0ca527e 373 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 14 24 3.1E-8 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFK25_02705 4294c648fad497c22cb17f45e0ca527e 373 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 1 13 3.1E-8 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFK25_02705 4294c648fad497c22cb17f45e0ca527e 373 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 300 306 3.1E-8 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFK25_02705 4294c648fad497c22cb17f45e0ca527e 373 TIGRFAM TIGR02352 thiamin_ThiO: glycine oxidase ThiO 3 351 4.5E-93 T 11-10-2018 IPR012727 Glycine oxidase ThiO GO:0016491|GO:0050660 KEGG: 00730+1.4.3.19|MetaCyc: PWY-7396|MetaCyc: PWY-7806 AFK25_02705 4294c648fad497c22cb17f45e0ca527e 373 Gene3D G3DSA:3.50.50.60 2 348 4.5E-109 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_02705 4294c648fad497c22cb17f45e0ca527e 373 Gene3D G3DSA:3.30.9.10 88 307 4.5E-109 T 11-10-2018 AFK25_05600 9bddb4c4950a0dcc3ad0cafea12266f5 88 SUPERFAMILY SSF160544 4 81 1.7E-24 T 11-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal AFK25_05600 9bddb4c4950a0dcc3ad0cafea12266f5 88 Gene3D G3DSA:3.40.1690.10 3 83 3.2E-26 T 11-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal AFK25_05600 9bddb4c4950a0dcc3ad0cafea12266f5 88 Pfam PF01312 FlhB HrpN YscU SpaS Family 6 77 1.1E-20 T 11-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 AFK25_07895 8fa45fbd045510cb46360fa671abed92 584 Gene3D G3DSA:1.20.1560.10 2 319 5.2E-79 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFK25_07895 8fa45fbd045510cb46360fa671abed92 584 SUPERFAMILY SSF90123 7 320 8.37E-76 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFK25_07895 8fa45fbd045510cb46360fa671abed92 584 SMART SM00382 362 554 8.6E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_07895 8fa45fbd045510cb46360fa671abed92 584 Pfam PF00664 ABC transporter transmembrane region 19 291 1.9E-46 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFK25_07895 8fa45fbd045510cb46360fa671abed92 584 Gene3D G3DSA:3.40.50.300 329 580 1.7E-83 T 11-10-2018 AFK25_07895 8fa45fbd045510cb46360fa671abed92 584 SUPERFAMILY SSF52540 330 572 5.43E-85 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_07895 8fa45fbd045510cb46360fa671abed92 584 Pfam PF00005 ABC transporter 353 500 5.0E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_07895 8fa45fbd045510cb46360fa671abed92 584 ProSitePatterns PS00211 ABC transporters family signature. 474 488 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_11320 9e65cb0f01ab6ae0640b90988d8112bc 255 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 96 116 - T 11-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 AFK25_11320 9e65cb0f01ab6ae0640b90988d8112bc 255 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 254 2.3E-69 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFK25_11320 9e65cb0f01ab6ae0640b90988d8112bc 255 SUPERFAMILY SSF52096 3 255 1.06E-86 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFK25_11320 9e65cb0f01ab6ae0640b90988d8112bc 255 Gene3D G3DSA:3.90.226.10 1 255 3.0E-95 T 11-10-2018 AFK25_10155 652db0b1b79123f7731776284a0e789a 316 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 108 313 3.6E-20 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_10155 652db0b1b79123f7731776284a0e789a 316 Gene3D G3DSA:1.10.3720.10 89 315 4.0E-36 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_10155 652db0b1b79123f7731776284a0e789a 316 SUPERFAMILY SSF161098 42 309 2.22E-35 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_10155 652db0b1b79123f7731776284a0e789a 316 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 36 312 1.4E-80 T 11-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 AFK25_10175 a575738362a7a2053c062afd89967ad5 202 PIRSF PIRSF000349 1 202 2.3E-90 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_10175 a575738362a7a2053c062afd89967ad5 202 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 164 171 - T 11-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_10175 a575738362a7a2053c062afd89967ad5 202 SUPERFAMILY SSF46609 1 91 5.37E-39 T 11-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_10175 a575738362a7a2053c062afd89967ad5 202 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 97 197 3.2E-45 T 11-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_10175 a575738362a7a2053c062afd89967ad5 202 Gene3D G3DSA:1.10.287.990 20 90 9.8E-33 T 11-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_10175 a575738362a7a2053c062afd89967ad5 202 SUPERFAMILY SSF54719 92 201 3.4E-51 T 11-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_10175 a575738362a7a2053c062afd89967ad5 202 Gene3D G3DSA:2.40.500.20 91 202 8.8E-55 T 11-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_10175 a575738362a7a2053c062afd89967ad5 202 PRINTS PR01703 Manganese superoxide dismutase signature 27 40 9.1E-28 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_10175 a575738362a7a2053c062afd89967ad5 202 PRINTS PR01703 Manganese superoxide dismutase signature 126 134 9.1E-28 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_10175 a575738362a7a2053c062afd89967ad5 202 PRINTS PR01703 Manganese superoxide dismutase signature 73 86 9.1E-28 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_10175 a575738362a7a2053c062afd89967ad5 202 PRINTS PR01703 Manganese superoxide dismutase signature 162 174 9.1E-28 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_10175 a575738362a7a2053c062afd89967ad5 202 PRINTS PR01703 Manganese superoxide dismutase signature 6 17 9.1E-28 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_10175 a575738362a7a2053c062afd89967ad5 202 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 3 90 1.4E-34 T 11-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_01360 bd8e1be0ed08083c420db6e00f7dd658 105 TIGRFAM TIGR02531 yecD_yerC: TrpR homolog YerC/YecD 7 94 2.8E-49 T 11-10-2018 IPR013368 TrpR homologue YerC/YecD AFK25_01360 bd8e1be0ed08083c420db6e00f7dd658 105 SUPERFAMILY SSF48295 3 95 2.35E-33 T 11-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 AFK25_01360 bd8e1be0ed08083c420db6e00f7dd658 105 Pfam PF01371 Trp repressor protein 10 93 1.9E-34 T 11-10-2018 IPR000831 Trp repressor GO:0003700|GO:0005622|GO:0006355 AFK25_01360 bd8e1be0ed08083c420db6e00f7dd658 105 Gene3D G3DSA:1.10.1270.10 2 104 6.4E-40 T 11-10-2018 IPR038116 TrpR-like superfamily AFK25_01360 bd8e1be0ed08083c420db6e00f7dd658 105 PIRSF PIRSF012508 1 100 9.3E-48 T 11-10-2018 IPR013368 TrpR homologue YerC/YecD AFK25_07525 2bb59f1e9cbd3f0ea40f0eeb9cd5aaed 131 SMART SM00345 16 75 1.6E-17 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_07525 2bb59f1e9cbd3f0ea40f0eeb9cd5aaed 131 SUPERFAMILY SSF46785 5 79 2.97E-22 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_07525 2bb59f1e9cbd3f0ea40f0eeb9cd5aaed 131 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 75 7.7E-16 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_07525 2bb59f1e9cbd3f0ea40f0eeb9cd5aaed 131 Gene3D G3DSA:1.10.10.10 9 127 9.2E-27 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_03595 b4093cb182fa2d44f70f36ed25c36a58 378 Gene3D G3DSA:3.40.50.2000 22 162 1.2E-64 T 11-10-2018 AFK25_03595 b4093cb182fa2d44f70f36ed25c36a58 378 Pfam PF13439 Glycosyltransferase Family 4 69 166 2.1E-13 T 11-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFK25_03595 b4093cb182fa2d44f70f36ed25c36a58 378 SUPERFAMILY SSF53756 2 373 2.63E-72 T 11-10-2018 AFK25_03595 b4093cb182fa2d44f70f36ed25c36a58 378 Gene3D G3DSA:3.40.50.2000 163 361 1.2E-64 T 11-10-2018 AFK25_03595 b4093cb182fa2d44f70f36ed25c36a58 378 Pfam PF00534 Glycosyl transferases group 1 183 355 5.6E-41 T 11-10-2018 IPR001296 Glycosyl transferase, family 1 AFK25_09930 68e30e6ed7cf32239be2b2a733ad9ea9 309 ProDom PD131510 MEMBRANE METAL-DEPENDENT ENZYME YQHQ SPANNING SIMILAR LIPOPROTEIN LIPOPROTEIN PROTEIN HYP001 53 292 1.0E-105 T 11-10-2018 IPR010787 Protein of unknown function DUF1385 AFK25_09930 68e30e6ed7cf32239be2b2a733ad9ea9 309 Pfam PF07136 Protein of unknown function (DUF1385) 53 296 3.9E-78 T 11-10-2018 IPR010787 Protein of unknown function DUF1385 AFK25_07765 9730a2ec76d25592a9d231c0922b1737 378 SMART SM00448 1 115 1.0E-32 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_07765 9730a2ec76d25592a9d231c0922b1737 378 SUPERFAMILY SSF52172 1 149 1.42E-35 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_07765 9730a2ec76d25592a9d231c0922b1737 378 Gene3D G3DSA:3.40.50.2300 1 136 5.2E-35 T 11-10-2018 AFK25_07765 9730a2ec76d25592a9d231c0922b1737 378 SMART SM00331 170 377 2.7E-26 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFK25_07765 9730a2ec76d25592a9d231c0922b1737 378 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 198 377 1.4E-38 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFK25_07765 9730a2ec76d25592a9d231c0922b1737 378 SUPERFAMILY SSF81606 183 377 3.79E-14 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFK25_07765 9730a2ec76d25592a9d231c0922b1737 378 Gene3D G3DSA:3.60.40.10 140 377 4.9E-51 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFK25_07765 9730a2ec76d25592a9d231c0922b1737 378 Pfam PF00072 Response regulator receiver domain 3 116 2.0E-26 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_10860 4305560f77e00176facc43358ff31acf 246 TIGRFAM TIGR00552 nadE: NAD+ synthetase 2 239 2.2E-76 T 11-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 AFK25_10860 4305560f77e00176facc43358ff31acf 246 Pfam PF02540 NAD synthase 5 239 4.3E-72 T 11-10-2018 IPR022310 NAD/GMP synthase AFK25_10860 4305560f77e00176facc43358ff31acf 246 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 1 243 50.292 T 11-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 AFK25_10860 4305560f77e00176facc43358ff31acf 246 Gene3D G3DSA:3.40.50.620 1 243 3.9E-79 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_10860 4305560f77e00176facc43358ff31acf 246 SUPERFAMILY SSF52402 1 245 1.68E-73 T 11-10-2018 AFK25_02990 3ab2532628402385110e1bd18455af05 449 SUPERFAMILY SSF58104 316 430 2.75E-10 T 11-10-2018 AFK25_02990 3ab2532628402385110e1bd18455af05 449 Pfam PF02743 Cache domain 35 258 4.1E-34 T 11-10-2018 IPR033479 Double Cache domain 1 AFK25_02990 3ab2532628402385110e1bd18455af05 449 Gene3D G3DSA:3.30.450.20 106 275 7.4E-33 T 11-10-2018 AFK25_02990 3ab2532628402385110e1bd18455af05 449 SUPERFAMILY SSF158472 297 347 1.15E-10 T 11-10-2018 AFK25_02990 3ab2532628402385110e1bd18455af05 449 Gene3D G3DSA:1.10.287.950 295 447 5.3E-19 T 11-10-2018 AFK25_02990 3ab2532628402385110e1bd18455af05 449 SUPERFAMILY SSF103190 82 175 6.67E-10 T 11-10-2018 IPR029151 Periplasmic sensor-like domain superfamily AFK25_02990 3ab2532628402385110e1bd18455af05 449 SMART SM00304 296 348 1.0E-13 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_02990 3ab2532628402385110e1bd18455af05 449 Pfam PF00672 HAMP domain 297 345 4.4E-13 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_13350 e15cce72e63617cc4a74dfb5a3014f01 609 SUPERFAMILY SSF55383 171 254 1.83E-11 T 11-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily AFK25_13350 e15cce72e63617cc4a74dfb5a3014f01 609 Pfam PF07833 Copper amine oxidase N-terminal domain 35 73 3.0E-5 T 11-10-2018 IPR012854 Copper amine oxidase-like, N-terminal AFK25_13350 e15cce72e63617cc4a74dfb5a3014f01 609 Pfam PF07833 Copper amine oxidase N-terminal domain 171 254 1.8E-10 T 11-10-2018 IPR012854 Copper amine oxidase-like, N-terminal AFK25_13350 e15cce72e63617cc4a74dfb5a3014f01 609 Pfam PF07833 Copper amine oxidase N-terminal domain 52 139 8.6E-29 T 11-10-2018 IPR012854 Copper amine oxidase-like, N-terminal AFK25_13350 e15cce72e63617cc4a74dfb5a3014f01 609 SUPERFAMILY SSF55383 54 137 2.42E-26 T 11-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily AFK25_13350 e15cce72e63617cc4a74dfb5a3014f01 609 Gene3D G3DSA:3.30.457.10 56 133 5.4E-25 T 11-10-2018 IPR036582 Copper amine oxidase-like, N-terminal domain superfamily AFK25_12915 f0abf1a20d0af72ffa932a435c1b3ea7 335 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 325 3.6E-142 T 11-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12915 f0abf1a20d0af72ffa932a435c1b3ea7 335 SMART SM00846 3 152 1.3E-100 T 11-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12915 f0abf1a20d0af72ffa932a435c1b3ea7 335 Gene3D G3DSA:3.30.360.10 151 315 2.8E-165 T 11-10-2018 AFK25_12915 f0abf1a20d0af72ffa932a435c1b3ea7 335 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 157 313 2.0E-73 T 11-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12915 f0abf1a20d0af72ffa932a435c1b3ea7 335 Gene3D G3DSA:3.40.50.720 4 329 2.8E-165 T 11-10-2018 AFK25_12915 f0abf1a20d0af72ffa932a435c1b3ea7 335 SUPERFAMILY SSF51735 3 168 3.75E-68 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_12915 f0abf1a20d0af72ffa932a435c1b3ea7 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 173 189 9.1E-44 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12915 f0abf1a20d0af72ffa932a435c1b3ea7 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 229 246 9.1E-44 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12915 f0abf1a20d0af72ffa932a435c1b3ea7 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 269 284 9.1E-44 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12915 f0abf1a20d0af72ffa932a435c1b3ea7 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 146 164 9.1E-44 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12915 f0abf1a20d0af72ffa932a435c1b3ea7 335 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 9.1E-44 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12915 f0abf1a20d0af72ffa932a435c1b3ea7 335 PIRSF PIRSF000149 1 334 2.3E-146 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12915 f0abf1a20d0af72ffa932a435c1b3ea7 335 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 150 157 - T 11-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12915 f0abf1a20d0af72ffa932a435c1b3ea7 335 SUPERFAMILY SSF55347 152 314 1.16E-75 T 11-10-2018 AFK25_12915 f0abf1a20d0af72ffa932a435c1b3ea7 335 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 3 102 5.7E-41 T 11-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_07980 aa9e2e72284d0ef956b3931037520f4d 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 382 409 4.2E-18 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_07980 aa9e2e72284d0ef956b3931037520f4d 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 411 440 4.2E-18 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_07980 aa9e2e72284d0ef956b3931037520f4d 560 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 3 28 4.2E-18 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_07980 aa9e2e72284d0ef956b3931037520f4d 560 Gene3D G3DSA:1.20.1480.50 164 262 2.3E-9 T 11-10-2018 AFK25_07980 aa9e2e72284d0ef956b3931037520f4d 560 Gene3D G3DSA:1.10.287.950 271 559 3.3E-64 T 11-10-2018 AFK25_07980 aa9e2e72284d0ef956b3931037520f4d 560 SUPERFAMILY SSF103190 77 165 4.19E-11 T 11-10-2018 IPR029151 Periplasmic sensor-like domain superfamily AFK25_07980 aa9e2e72284d0ef956b3931037520f4d 560 SMART SM00304 200 255 3.4E-6 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_07980 aa9e2e72284d0ef956b3931037520f4d 560 Pfam PF17202 Single cache domain 3 71 174 2.1E-32 T 11-10-2018 IPR033463 Single cache domain 3 AFK25_07980 aa9e2e72284d0ef956b3931037520f4d 560 SMART SM00283 284 559 1.3E-61 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_07980 aa9e2e72284d0ef956b3931037520f4d 560 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 330 511 8.2E-39 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_07980 aa9e2e72284d0ef956b3931037520f4d 560 SUPERFAMILY SSF58104 230 558 2.22E-64 T 11-10-2018 AFK25_10370 dbf734cc5e7b5e004ca1849df9a3ebe6 312 SUPERFAMILY SSF53335 77 310 4.67E-51 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_10370 dbf734cc5e7b5e004ca1849df9a3ebe6 312 TIGRFAM TIGR00406 prmA: ribosomal protein L11 methyltransferase 3 305 1.6E-107 T 11-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 AFK25_10370 dbf734cc5e7b5e004ca1849df9a3ebe6 312 PIRSF PIRSF000401 1 312 2.9E-115 T 11-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 AFK25_10370 dbf734cc5e7b5e004ca1849df9a3ebe6 312 Gene3D G3DSA:3.40.50.150 116 312 2.6E-67 T 11-10-2018 AFK25_10370 dbf734cc5e7b5e004ca1849df9a3ebe6 312 Hamap MF_00735 Ribosomal protein L11 methyltransferase [prmA]. 3 311 36.969 T 11-10-2018 IPR004498 Ribosomal protein L11 methyltransferase GO:0006479|GO:0008276 AFK25_10370 dbf734cc5e7b5e004ca1849df9a3ebe6 312 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 2 311 6.8E-109 T 11-10-2018 AFK25_07015 b8297a8b5da47496b8853631ea79067f 618 Gene3D G3DSA:3.40.930.10 1 150 1.8E-51 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 AFK25_07015 b8297a8b5da47496b8853631ea79067f 618 TIGRFAM TIGR01427 PTS_IIC_fructo: PTS system, Fru family, IIC component 277 613 4.1E-142 T 11-10-2018 IPR006327 Phosphotransferase system, fructose IIC component GO:0005351|GO:0008982|GO:0009401|GO:0016021 AFK25_07015 b8297a8b5da47496b8853631ea79067f 618 Gene3D G3DSA:3.40.50.2300 153 266 5.9E-45 T 11-10-2018 AFK25_07015 b8297a8b5da47496b8853631ea79067f 618 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 168 257 1.6E-17 T 11-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 AFK25_07015 b8297a8b5da47496b8853631ea79067f 618 TIGRFAM TIGR00848 fruA: PTS system, fructose subfamily, IIA component 6 133 1.4E-40 T 11-10-2018 IPR004715 Phosphotransferase system, IIA component fructose subfamily GO:0008982|GO:0009401|GO:0016021 AFK25_07015 b8297a8b5da47496b8853631ea79067f 618 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 6 148 1.2E-42 T 11-10-2018 IPR002178 PTS EIIA type-2 domain AFK25_07015 b8297a8b5da47496b8853631ea79067f 618 SUPERFAMILY SSF52794 165 267 3.14E-39 T 11-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 AFK25_07015 b8297a8b5da47496b8853631ea79067f 618 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 52 68 - T 11-10-2018 IPR002178 PTS EIIA type-2 domain AFK25_07015 b8297a8b5da47496b8853631ea79067f 618 Pfam PF02378 Phosphotransferase system, EIIC 290 559 1.1E-15 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 AFK25_07015 b8297a8b5da47496b8853631ea79067f 618 SUPERFAMILY SSF55804 1 148 6.54E-45 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 AFK25_07015 b8297a8b5da47496b8853631ea79067f 618 TIGRFAM TIGR00829 FRU: PTS system, Fru family, IIB component 168 249 1.3E-31 T 11-10-2018 IPR003353 Phosphotransferase system, fructose-specific IIB subunit GO:0009401|GO:0022877 KEGG: 00051+2.7.1.202 AFK25_00985 6907f71462d83c3a3a1a9109e44d8340 234 Gene3D G3DSA:3.30.565.40 22 142 4.9E-29 T 11-10-2018 AFK25_00985 6907f71462d83c3a3a1a9109e44d8340 234 Pfam PF11738 Protein of unknown function (DUF3298) 146 222 3.2E-19 T 11-10-2018 IPR021729 Domain of unknown function DUF3298 AFK25_00985 6907f71462d83c3a3a1a9109e44d8340 234 Gene3D G3DSA:3.90.640.20 144 234 1.6E-25 T 11-10-2018 IPR037126 PdaC/RsiV-like superfamily AFK25_00985 6907f71462d83c3a3a1a9109e44d8340 234 Pfam PF13739 Domain of unknown function (DUF4163) 32 128 2.0E-23 T 11-10-2018 IPR025303 Deacetylase PdaC AFK25_06720 9f22c1f950dd248755274663fa764512 192 PIRSF PIRSF000847 1 192 3.6E-53 T 11-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 AFK25_06720 9f22c1f950dd248755274663fa764512 192 TIGRFAM TIGR00560 pgsA: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 1 187 1.2E-66 T 11-10-2018 IPR004570 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase GO:0008444|GO:0008654|GO:0016021 KEGG: 00564+2.7.8.5|MetaCyc: PWY-5269|MetaCyc: PWY-5668|MetaCyc: PWY-7817 AFK25_06720 9f22c1f950dd248755274663fa764512 192 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 59 81 - T 11-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFK25_06720 9f22c1f950dd248755274663fa764512 192 Pfam PF01066 CDP-alcohol phosphatidyltransferase 2 81 2.3E-17 T 11-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFK25_06720 9f22c1f950dd248755274663fa764512 192 Gene3D G3DSA:1.20.120.1760 3 182 1.1E-10 T 11-10-2018 AFK25_08140 2313263451876319daff7c74568c92c5 372 Hamap MF_00456 Glutamate 5-kinase [proB]. 4 258 35.407 T 11-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFK25_08140 2313263451876319daff7c74568c92c5 372 TIGRFAM TIGR01027 proB: glutamate 5-kinase 4 364 1.3E-133 T 11-10-2018 IPR005715 Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFK25_08140 2313263451876319daff7c74568c92c5 372 PIRSF PIRSF000729 1 367 3.1E-134 T 11-10-2018 IPR011529 Glutamate 5-kinase GO:0004349|GO:0005737|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922 AFK25_08140 2313263451876319daff7c74568c92c5 372 Pfam PF01472 PUA domain 276 349 6.3E-19 T 11-10-2018 IPR002478 PUA domain GO:0003723 AFK25_08140 2313263451876319daff7c74568c92c5 372 SUPERFAMILY SSF88697 276 365 5.52E-18 T 11-10-2018 IPR015947 PUA-like superfamily AFK25_08140 2313263451876319daff7c74568c92c5 372 SMART SM00359 276 358 8.7E-14 T 11-10-2018 IPR002478 PUA domain GO:0003723 AFK25_08140 2313263451876319daff7c74568c92c5 372 Gene3D G3DSA:2.30.130.10 265 365 1.8E-28 T 11-10-2018 IPR036974 PUA domain superfamily GO:0003723 AFK25_08140 2313263451876319daff7c74568c92c5 372 Pfam PF00696 Amino acid kinase family 4 231 2.3E-40 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AFK25_08140 2313263451876319daff7c74568c92c5 372 SUPERFAMILY SSF53633 4 253 1.07E-65 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFK25_08140 2313263451876319daff7c74568c92c5 372 ProSitePatterns PS00902 Glutamate 5-kinase signature. 205 222 - T 11-10-2018 IPR019797 Glutamate 5-kinase, conserved site GO:0004349|GO:0006561 KEGG: 00330+2.7.2.11|KEGG: 00332+2.7.2.11|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFK25_08140 2313263451876319daff7c74568c92c5 372 Gene3D G3DSA:3.40.1160.10 1 258 3.9E-82 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFK25_08140 2313263451876319daff7c74568c92c5 372 PRINTS PR00474 Glutamate 5-kinase family signature 41 55 1.1E-50 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFK25_08140 2313263451876319daff7c74568c92c5 372 PRINTS PR00474 Glutamate 5-kinase family signature 75 103 1.1E-50 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFK25_08140 2313263451876319daff7c74568c92c5 372 PRINTS PR00474 Glutamate 5-kinase family signature 115 136 1.1E-50 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFK25_08140 2313263451876319daff7c74568c92c5 372 PRINTS PR00474 Glutamate 5-kinase family signature 207 227 1.1E-50 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFK25_08140 2313263451876319daff7c74568c92c5 372 PRINTS PR00474 Glutamate 5-kinase family signature 147 174 1.1E-50 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFK25_11865 f7e89af6a4d468854fec42cb1e48e17a 214 Pfam PF01842 ACT domain 139 197 8.4E-11 T 11-10-2018 IPR002912 ACT domain AFK25_11865 f7e89af6a4d468854fec42cb1e48e17a 214 SMART SM00116 81 128 6.7E-13 T 11-10-2018 IPR000644 CBS domain AFK25_11865 f7e89af6a4d468854fec42cb1e48e17a 214 SMART SM00116 10 58 4.8E-9 T 11-10-2018 IPR000644 CBS domain AFK25_11865 f7e89af6a4d468854fec42cb1e48e17a 214 SUPERFAMILY SSF54631 1 129 2.15E-32 T 11-10-2018 AFK25_11865 f7e89af6a4d468854fec42cb1e48e17a 214 SUPERFAMILY SSF55021 138 206 2.36E-11 T 11-10-2018 AFK25_11865 f7e89af6a4d468854fec42cb1e48e17a 214 Gene3D G3DSA:3.30.70.260 133 202 1.3E-7 T 11-10-2018 AFK25_11865 f7e89af6a4d468854fec42cb1e48e17a 214 Pfam PF00571 CBS domain 3 56 7.9E-13 T 11-10-2018 IPR000644 CBS domain AFK25_11865 f7e89af6a4d468854fec42cb1e48e17a 214 Pfam PF00571 CBS domain 76 127 3.7E-10 T 11-10-2018 IPR000644 CBS domain AFK25_11865 f7e89af6a4d468854fec42cb1e48e17a 214 Gene3D G3DSA:3.10.580.10 1 132 2.4E-36 T 11-10-2018 AFK25_09500 b2b3637c1e7f47346c519431414665ee 175 Gene3D G3DSA:1.20.120.520 16 174 1.2E-31 T 11-10-2018 AFK25_09500 b2b3637c1e7f47346c519431414665ee 175 Pfam PF01814 Hemerythrin HHE cation binding domain 20 154 5.3E-16 T 11-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 AFK25_06425 74c762c4afac60c9ff9f386a68689e82 146 Gene3D G3DSA:1.10.10.10 1 144 4.1E-34 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_06425 74c762c4afac60c9ff9f386a68689e82 146 Pfam PF01047 MarR family 36 93 2.5E-17 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_06425 74c762c4afac60c9ff9f386a68689e82 146 SUPERFAMILY SSF46785 7 140 8.54E-34 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_06425 74c762c4afac60c9ff9f386a68689e82 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 119 139 4.9E-14 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_06425 74c762c4afac60c9ff9f386a68689e82 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 89 105 4.9E-14 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_06425 74c762c4afac60c9ff9f386a68689e82 146 PRINTS PR00598 Bacterial regulatory protein MarR family signature 70 85 4.9E-14 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_06425 74c762c4afac60c9ff9f386a68689e82 146 SMART SM00347 29 129 3.4E-31 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_06425 74c762c4afac60c9ff9f386a68689e82 146 ProSitePatterns PS01117 MarR-type HTH domain signature. 68 102 - T 11-10-2018 IPR023187 Transcriptional regulator MarR-type, conserved site AFK25_00645 8d2c7f53b4eed30c1870a2d8a8a8ad65 66 ProSitePatterns PS00579 Ribosomal protein L29 signature. 39 53 - T 11-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00645 8d2c7f53b4eed30c1870a2d8a8a8ad65 66 SUPERFAMILY SSF46561 1 63 4.58E-24 T 11-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00645 8d2c7f53b4eed30c1870a2d8a8a8ad65 66 Gene3D G3DSA:1.10.287.310 1 66 4.0E-31 T 11-10-2018 AFK25_00645 8d2c7f53b4eed30c1870a2d8a8a8ad65 66 TIGRFAM TIGR00012 L29: ribosomal protein uL29 5 60 8.2E-25 T 11-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00645 8d2c7f53b4eed30c1870a2d8a8a8ad65 66 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 1 60 19.6 T 11-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00645 8d2c7f53b4eed30c1870a2d8a8a8ad65 66 Pfam PF00831 Ribosomal L29 protein 4 60 9.8E-27 T 11-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_10385 31b188ece75612fe8efa41262eceb561 193 Hamap MF_01151 Protein GrpE [grpE]. 2 193 21.873 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFK25_10385 31b188ece75612fe8efa41262eceb561 193 SUPERFAMILY SSF51064 138 193 9.68E-21 T 11-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 AFK25_10385 31b188ece75612fe8efa41262eceb561 193 SUPERFAMILY SSF58014 45 137 1.83E-26 T 11-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 AFK25_10385 31b188ece75612fe8efa41262eceb561 193 ProSitePatterns PS01071 grpE protein signature. 148 191 - T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFK25_10385 31b188ece75612fe8efa41262eceb561 193 Pfam PF01025 GrpE 30 193 1.8E-57 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFK25_10385 31b188ece75612fe8efa41262eceb561 193 PRINTS PR00773 GrpE protein signature 91 106 4.2E-31 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFK25_10385 31b188ece75612fe8efa41262eceb561 193 PRINTS PR00773 GrpE protein signature 172 191 4.2E-31 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFK25_10385 31b188ece75612fe8efa41262eceb561 193 PRINTS PR00773 GrpE protein signature 145 160 4.2E-31 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFK25_10385 31b188ece75612fe8efa41262eceb561 193 PRINTS PR00773 GrpE protein signature 63 79 4.2E-31 T 11-10-2018 IPR000740 GrpE nucleotide exchange factor GO:0000774|GO:0006457|GO:0042803|GO:0051087 Reactome: R-HSA-1268020 AFK25_10385 31b188ece75612fe8efa41262eceb561 193 Gene3D G3DSA:2.30.22.10 137 193 2.2E-27 T 11-10-2018 IPR009012 GrpE nucleotide exchange factor, head GO:0006457 Reactome: R-HSA-1268020 AFK25_10385 31b188ece75612fe8efa41262eceb561 193 Gene3D G3DSA:3.90.20.20 2 136 1.5E-27 T 11-10-2018 IPR013805 GrpE nucleotide exchange factor, coiled-coil Reactome: R-HSA-1268020 AFK25_07835 e3b0f66d9affcad45d0d32c640b99089 642 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 101 216 1.6E-9 T 11-10-2018 IPR000014 PAS domain AFK25_07835 e3b0f66d9affcad45d0d32c640b99089 642 SMART SM00091 95 160 3.8E-4 T 11-10-2018 IPR000014 PAS domain AFK25_07835 e3b0f66d9affcad45d0d32c640b99089 642 Pfam PF00563 EAL domain 387 620 2.4E-78 T 11-10-2018 IPR001633 EAL domain AFK25_07835 e3b0f66d9affcad45d0d32c640b99089 642 Gene3D G3DSA:3.30.450.20 96 210 2.6E-19 T 11-10-2018 AFK25_07835 e3b0f66d9affcad45d0d32c640b99089 642 Gene3D G3DSA:3.30.70.270 215 385 2.0E-45 T 11-10-2018 AFK25_07835 e3b0f66d9affcad45d0d32c640b99089 642 Pfam PF00989 PAS fold 102 206 1.7E-12 T 11-10-2018 IPR013767 PAS fold GO:0006355 AFK25_07835 e3b0f66d9affcad45d0d32c640b99089 642 SMART SM00086 167 209 1.6E-6 T 11-10-2018 IPR001610 PAC motif AFK25_07835 e3b0f66d9affcad45d0d32c640b99089 642 SMART SM00052 381 626 5.1E-112 T 11-10-2018 IPR001633 EAL domain AFK25_07835 e3b0f66d9affcad45d0d32c640b99089 642 SUPERFAMILY SSF141868 386 635 8.11E-90 T 11-10-2018 IPR035919 EAL domain superfamily AFK25_07835 e3b0f66d9affcad45d0d32c640b99089 642 Gene3D G3DSA:3.20.20.450 386 642 4.1E-97 T 11-10-2018 IPR035919 EAL domain superfamily AFK25_07835 e3b0f66d9affcad45d0d32c640b99089 642 SUPERFAMILY SSF55073 225 376 1.49E-42 T 11-10-2018 IPR029787 Nucleotide cyclase AFK25_07835 e3b0f66d9affcad45d0d32c640b99089 642 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 219 373 9.6E-31 T 11-10-2018 IPR000160 GGDEF domain AFK25_07835 e3b0f66d9affcad45d0d32c640b99089 642 SUPERFAMILY SSF55785 102 210 9.27E-17 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_07835 e3b0f66d9affcad45d0d32c640b99089 642 SMART SM00267 209 376 5.6E-43 T 11-10-2018 IPR000160 GGDEF domain AFK25_07835 e3b0f66d9affcad45d0d32c640b99089 642 Pfam PF00990 Diguanylate cyclase, GGDEF domain 221 370 2.8E-36 T 11-10-2018 IPR000160 GGDEF domain AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 Pfam PF09334 tRNA synthetases class I (M) 155 361 7.0E-72 T 11-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 Pfam PF09334 tRNA synthetases class I (M) 6 150 5.0E-54 T 11-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 Pfam PF01588 Putative tRNA binding domain 555 646 2.4E-27 T 11-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 SUPERFAMILY SSF50249 543 648 6.12E-34 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 Pfam PF08264 Anticodon-binding domain of tRNA 385 519 7.4E-9 T 11-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 515 649 3.6E-49 T 11-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 Gene3D G3DSA:2.40.50.140 539 649 6.3E-38 T 11-10-2018 AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 PRINTS PR01041 Methionyl-tRNA synthetase signature 8 21 2.2E-33 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 PRINTS PR01041 Methionyl-tRNA synthetase signature 40 54 2.2E-33 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 PRINTS PR01041 Methionyl-tRNA synthetase signature 224 235 2.2E-33 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 PRINTS PR01041 Methionyl-tRNA synthetase signature 349 360 2.2E-33 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 PRINTS PR01041 Methionyl-tRNA synthetase signature 88 99 2.2E-33 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 PRINTS PR01041 Methionyl-tRNA synthetase signature 257 272 2.2E-33 T 11-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 Gene3D G3DSA:2.170.220.10 117 226 9.2E-158 T 11-10-2018 AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 Hamap MF_01228 Methionine--tRNA ligase [metG]. 2 510 52.787 T 11-10-2018 IPR023457 Methionine-tRNA synthetase, type 2 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 15 24 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 SUPERFAMILY SSF52374 3 348 1.27E-122 T 11-10-2018 AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 SUPERFAMILY SSF47323 351 562 5.05E-46 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 Gene3D G3DSA:1.10.730.10 339 509 1.4E-53 T 11-10-2018 AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 6 511 1.9E-187 T 11-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AFK25_00215 e6fe903fe2c335d5d7740e282cd2729d 649 Gene3D G3DSA:3.40.50.620 6 334 9.2E-158 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_04535 c0d7f570ec50312ef43b44aa0f422d71 229 Pfam PF01370 NAD dependent epimerase/dehydratase family 6 114 4.5E-12 T 11-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFK25_04535 c0d7f570ec50312ef43b44aa0f422d71 229 SUPERFAMILY SSF51735 3 207 1.85E-44 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_04535 c0d7f570ec50312ef43b44aa0f422d71 229 Gene3D G3DSA:3.40.50.720 1 222 1.0E-63 T 11-10-2018 AFK25_07000 2ca73943e5715e497bfa75a7a8db9557 607 SUPERFAMILY SSF55073 239 400 7.45E-42 T 11-10-2018 IPR029787 Nucleotide cyclase AFK25_07000 2ca73943e5715e497bfa75a7a8db9557 607 Gene3D G3DSA:1.10.3210.10 414 602 6.7E-61 T 11-10-2018 AFK25_07000 2ca73943e5715e497bfa75a7a8db9557 607 SMART SM00267 224 398 9.3E-43 T 11-10-2018 IPR000160 GGDEF domain AFK25_07000 2ca73943e5715e497bfa75a7a8db9557 607 Pfam PF00990 Diguanylate cyclase, GGDEF domain 234 394 6.5E-38 T 11-10-2018 IPR000160 GGDEF domain AFK25_07000 2ca73943e5715e497bfa75a7a8db9557 607 SMART SM00471 427 562 6.1E-12 T 11-10-2018 IPR003607 HD/PDEase domain AFK25_07000 2ca73943e5715e497bfa75a7a8db9557 607 Gene3D G3DSA:3.30.70.270 222 401 1.4E-48 T 11-10-2018 AFK25_07000 2ca73943e5715e497bfa75a7a8db9557 607 SUPERFAMILY SSF109604 421 593 1.39E-37 T 11-10-2018 AFK25_07000 2ca73943e5715e497bfa75a7a8db9557 607 TIGRFAM TIGR00277 HDIG: HDIG domain 431 521 2.6E-8 T 11-10-2018 IPR006675 HDIG domain AFK25_07000 2ca73943e5715e497bfa75a7a8db9557 607 Pfam PF01966 HD domain 431 553 1.2E-19 T 11-10-2018 IPR006674 HD domain AFK25_07000 2ca73943e5715e497bfa75a7a8db9557 607 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 231 397 2.2E-40 T 11-10-2018 IPR000160 GGDEF domain AFK25_05495 7dcc321d77a234a73a3b3315e4f7108c 682 SUPERFAMILY SSF50249 5 168 6.43E-27 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_05495 7dcc321d77a234a73a3b3315e4f7108c 682 SUPERFAMILY SSF52540 436 638 6.98E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_05495 7dcc321d77a234a73a3b3315e4f7108c 682 Pfam PF17191 RecG wedge domain 11 161 1.2E-17 T 11-10-2018 IPR033454 RecG, wedge domain AFK25_05495 7dcc321d77a234a73a3b3315e4f7108c 682 SUPERFAMILY SSF52540 173 436 7.48E-65 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_05495 7dcc321d77a234a73a3b3315e4f7108c 682 Pfam PF00271 Helicase conserved C-terminal domain 453 572 2.6E-20 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_05495 7dcc321d77a234a73a3b3315e4f7108c 682 Pfam PF00270 DEAD/DEAH box helicase 259 417 5.1E-19 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFK25_05495 7dcc321d77a234a73a3b3315e4f7108c 682 Gene3D G3DSA:3.40.50.300 196 434 2.2E-89 T 11-10-2018 AFK25_05495 7dcc321d77a234a73a3b3315e4f7108c 682 SMART SM00490 488 573 2.5E-23 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_05495 7dcc321d77a234a73a3b3315e4f7108c 682 SMART SM00487 253 443 6.1E-35 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFK25_05495 7dcc321d77a234a73a3b3315e4f7108c 682 Gene3D G3DSA:3.40.50.300 441 613 5.5E-59 T 11-10-2018 AFK25_05495 7dcc321d77a234a73a3b3315e4f7108c 682 TIGRFAM TIGR00643 recG: ATP-dependent DNA helicase RecG 26 648 7.3E-250 T 11-10-2018 IPR004609 ATP-dependent DNA helicase RecG GO:0004003|GO:0006281|GO:0006310 AFK25_05495 7dcc321d77a234a73a3b3315e4f7108c 682 Gene3D G3DSA:2.40.50.140 46 141 1.8E-9 T 11-10-2018 AFK25_11370 e3aa86c988d020c9e9e6b9ee2b498522 804 SMART SM00874 411 479 5.2E-29 T 11-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AFK25_11370 e3aa86c988d020c9e9e6b9ee2b498522 804 Gene3D G3DSA:3.30.70.380 711 803 2.4E-32 T 11-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 AFK25_11370 e3aa86c988d020c9e9e6b9ee2b498522 804 Hamap MF_00283 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 797 48.047 T 11-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 AFK25_11370 e3aa86c988d020c9e9e6b9ee2b498522 804 SUPERFAMILY SSF54991 705 803 2.35E-32 T 11-10-2018 IPR036690 Ferrodoxin-fold anticodon-binding domain superfamily KEGG: 00970+6.1.1.20 AFK25_11370 e3aa86c988d020c9e9e6b9ee2b498522 804 Gene3D G3DSA:3.30.56.10 411 483 7.6E-26 T 11-10-2018 AFK25_11370 e3aa86c988d020c9e9e6b9ee2b498522 804 Pfam PF03147 Ferredoxin-fold anticodon binding domain 710 803 4.8E-30 T 11-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 AFK25_11370 e3aa86c988d020c9e9e6b9ee2b498522 804 SUPERFAMILY SSF55681 475 697 9.69E-55 T 11-10-2018 AFK25_11370 e3aa86c988d020c9e9e6b9ee2b498522 804 Gene3D G3DSA:3.50.40.10 204 405 1.6E-83 T 11-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 AFK25_11370 e3aa86c988d020c9e9e6b9ee2b498522 804 Pfam PF03483 B3/4 domain 222 394 1.2E-68 T 11-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 AFK25_11370 e3aa86c988d020c9e9e6b9ee2b498522 804 SUPERFAMILY SSF56037 210 406 1.54E-73 T 11-10-2018 AFK25_11370 e3aa86c988d020c9e9e6b9ee2b498522 804 SUPERFAMILY SSF50249 37 199 5.14E-48 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_11370 e3aa86c988d020c9e9e6b9ee2b498522 804 SMART SM00873 221 394 9.5E-93 T 11-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 AFK25_11370 e3aa86c988d020c9e9e6b9ee2b498522 804 Gene3D G3DSA:3.30.930.10 495 699 1.4E-64 T 11-10-2018 AFK25_11370 e3aa86c988d020c9e9e6b9ee2b498522 804 Pfam PF01588 Putative tRNA binding domain 46 152 1.6E-27 T 11-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 AFK25_11370 e3aa86c988d020c9e9e6b9ee2b498522 804 Pfam PF03484 tRNA synthetase B5 domain 414 479 4.6E-21 T 11-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AFK25_11370 e3aa86c988d020c9e9e6b9ee2b498522 804 TIGRFAM TIGR00472 pheT_bact: phenylalanine--tRNA ligase, beta subunit 1 803 2.7E-276 T 11-10-2018 IPR004532 Phenylalanine-tRNA ligase, class IIc, beta subunit GO:0000287|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 AFK25_11370 e3aa86c988d020c9e9e6b9ee2b498522 804 SMART SM00896 710 803 6.2E-47 T 11-10-2018 IPR005121 Ferrodoxin-fold anticodon-binding domain KEGG: 00970+6.1.1.20 AFK25_11370 e3aa86c988d020c9e9e6b9ee2b498522 804 Gene3D G3DSA:3.30.56.10 4 189 3.5E-71 T 11-10-2018 AFK25_11370 e3aa86c988d020c9e9e6b9ee2b498522 804 Gene3D G3DSA:2.40.50.140 40 161 3.5E-71 T 11-10-2018 AFK25_11370 e3aa86c988d020c9e9e6b9ee2b498522 804 SUPERFAMILY SSF46955 412 483 1.46E-20 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily AFK25_01950 0bf1104e3cf1976b02f62659236bf1e5 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 296 2.2E-33 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_01950 0bf1104e3cf1976b02f62659236bf1e5 297 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 20 72 1.5E-17 T 11-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain AFK25_01950 0bf1104e3cf1976b02f62659236bf1e5 297 Gene3D G3DSA:1.10.3720.10 86 292 9.1E-28 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_01950 0bf1104e3cf1976b02f62659236bf1e5 297 SUPERFAMILY SSF161098 90 280 2.49E-33 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_07560 cbe01e4ad33abe79ea4b59f3b5e18ab3 417 Pfam PF13426 PAS domain 97 183 4.6E-7 T 11-10-2018 IPR000014 PAS domain AFK25_07560 cbe01e4ad33abe79ea4b59f3b5e18ab3 417 SUPERFAMILY SSF55874 253 413 3.67E-39 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_07560 cbe01e4ad33abe79ea4b59f3b5e18ab3 417 Gene3D G3DSA:1.10.287.130 186 262 2.2E-16 T 11-10-2018 AFK25_07560 cbe01e4ad33abe79ea4b59f3b5e18ab3 417 SMART SM00388 198 263 1.8E-8 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_07560 cbe01e4ad33abe79ea4b59f3b5e18ab3 417 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 309 413 9.4E-22 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_07560 cbe01e4ad33abe79ea4b59f3b5e18ab3 417 SUPERFAMILY SSF55785 83 181 3.49E-11 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_07560 cbe01e4ad33abe79ea4b59f3b5e18ab3 417 SMART SM00387 308 415 3.7E-31 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_07560 cbe01e4ad33abe79ea4b59f3b5e18ab3 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 393 3.2E-19 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_07560 cbe01e4ad33abe79ea4b59f3b5e18ab3 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 346 360 3.2E-19 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_07560 cbe01e4ad33abe79ea4b59f3b5e18ab3 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 364 374 3.2E-19 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_07560 cbe01e4ad33abe79ea4b59f3b5e18ab3 417 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 412 3.2E-19 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_07560 cbe01e4ad33abe79ea4b59f3b5e18ab3 417 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 81 194 3.5E-7 T 11-10-2018 IPR000014 PAS domain AFK25_07560 cbe01e4ad33abe79ea4b59f3b5e18ab3 417 SUPERFAMILY SSF47384 192 260 1.02E-11 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFK25_07560 cbe01e4ad33abe79ea4b59f3b5e18ab3 417 Pfam PF00512 His Kinase A (phospho-acceptor) domain 200 259 2.7E-11 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_07560 cbe01e4ad33abe79ea4b59f3b5e18ab3 417 Gene3D G3DSA:3.30.565.10 264 416 1.0E-40 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_07560 cbe01e4ad33abe79ea4b59f3b5e18ab3 417 SMART SM00091 84 150 0.0081 T 11-10-2018 IPR000014 PAS domain AFK25_07560 cbe01e4ad33abe79ea4b59f3b5e18ab3 417 Gene3D G3DSA:3.30.450.20 76 185 2.9E-11 T 11-10-2018 AFK25_13810 9a3ad2a5bf8891935ffaaf3225731118 366 Gene3D G3DSA:1.10.645.20 4 366 1.6E-156 T 11-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13810 9a3ad2a5bf8891935ffaaf3225731118 366 Hamap MF_01358 NAD(P)H-quinone oxidoreductase subunit H, chloroplastic [ndhH]. 3 366 47.186 T 11-10-2018 IPR022885 NAD(P)H-quinone oxidoreductase subunit D/H GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13810 9a3ad2a5bf8891935ffaaf3225731118 366 SUPERFAMILY SSF56762 16 365 5.49E-123 T 11-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13810 9a3ad2a5bf8891935ffaaf3225731118 366 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 291 365 1.8E-26 T 11-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13810 9a3ad2a5bf8891935ffaaf3225731118 366 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 120 291 7.7E-69 T 11-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_02775 2073b0b88332ef1c07b8ee692484a7d6 369 PIRSF PIRSF032178 1 368 3.4E-119 T 11-10-2018 IPR016991 Protein of unknown function UCP032178 AFK25_02775 2073b0b88332ef1c07b8ee692484a7d6 369 Pfam PF04286 Protein of unknown function (DUF445) 12 366 2.6E-74 T 11-10-2018 IPR007383 Protein of unknown function DUF445 AFK25_00695 cbae6364c5a0a5f928192e616623b25d 62 ProSitePatterns PS00634 Ribosomal protein L30 signature. 23 55 - T 11-10-2018 IPR018038 Ribosomal protein L30, conserved site AFK25_00695 cbae6364c5a0a5f928192e616623b25d 62 PIRSF PIRSF002211 1 61 3.5E-31 T 11-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00695 cbae6364c5a0a5f928192e616623b25d 62 TIGRFAM TIGR01308 rpmD_bact: ribosomal protein uL30 6 59 9.0E-28 T 11-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00695 cbae6364c5a0a5f928192e616623b25d 62 Hamap MF_01371_B 50S ribosomal protein L30 [rpmD]. 2 59 20.627 T 11-10-2018 IPR005996 Ribosomal protein L30, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00695 cbae6364c5a0a5f928192e616623b25d 62 SUPERFAMILY SSF55129 3 60 2.22E-23 T 11-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily AFK25_00695 cbae6364c5a0a5f928192e616623b25d 62 Pfam PF00327 Ribosomal protein L30p/L7e 5 55 1.1E-21 T 11-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain AFK25_00695 cbae6364c5a0a5f928192e616623b25d 62 Gene3D G3DSA:3.30.1390.20 1 59 6.5E-29 T 11-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily AFK25_09485 3169e939047a02c420c2eb03922cba48 183 TIGRFAM TIGR00684 narJ: nitrate reductase molybdenum cofactor assembly chaperone 14 165 1.0E-39 T 11-10-2018 IPR003765 Nitrate reductase chaperone, NarJ GO:0051082|GO:0051131 AFK25_09485 3169e939047a02c420c2eb03922cba48 183 Gene3D G3DSA:1.20.120.700 12 162 2.0E-10 T 11-10-2018 AFK25_09485 3169e939047a02c420c2eb03922cba48 183 SUPERFAMILY SSF89155 9 170 9.68E-27 T 11-10-2018 IPR036411 TorD-like superfamily AFK25_09485 3169e939047a02c420c2eb03922cba48 183 Gene3D G3DSA:1.10.4070.10 70 154 2.0E-10 T 11-10-2018 AFK25_09485 3169e939047a02c420c2eb03922cba48 183 Pfam PF02613 Nitrate reductase delta subunit 47 127 7.8E-6 T 11-10-2018 IPR020945 DMSO/Nitrate reductase chaperone AFK25_11395 7945d856d1df05a94f376272f5b4d4bb 499 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 132 144 - T 11-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFK25_11395 7945d856d1df05a94f376272f5b4d4bb 499 Gene3D G3DSA:3.30.420.40 249 491 1.1E-73 T 11-10-2018 AFK25_11395 7945d856d1df05a94f376272f5b4d4bb 499 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 247 8.4E-70 T 11-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 AFK25_11395 7945d856d1df05a94f376272f5b4d4bb 499 Gene3D G3DSA:3.30.420.40 1 247 9.1E-84 T 11-10-2018 AFK25_11395 7945d856d1df05a94f376272f5b4d4bb 499 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 257 442 6.6E-33 T 11-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 AFK25_11395 7945d856d1df05a94f376272f5b4d4bb 499 TIGRFAM TIGR01312 XylB: xylulokinase 5 484 5.3E-188 T 11-10-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 AFK25_11395 7945d856d1df05a94f376272f5b4d4bb 499 PIRSF PIRSF000538 2 496 9.8E-161 T 11-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFK25_11395 7945d856d1df05a94f376272f5b4d4bb 499 SUPERFAMILY SSF53067 3 249 6.11E-78 T 11-10-2018 AFK25_11395 7945d856d1df05a94f376272f5b4d4bb 499 SUPERFAMILY SSF53067 249 489 5.61E-66 T 11-10-2018 AFK25_11395 7945d856d1df05a94f376272f5b4d4bb 499 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 355 375 - T 11-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFK25_01285 c6d3d8c180039a9b807973b56f1f825a 162 Hamap MF_01929 N5-carboxyaminoimidazole ribonucleotide mutase [purE]. 5 158 33.159 T 11-10-2018 IPR033747 Class I PurE AFK25_01285 c6d3d8c180039a9b807973b56f1f825a 162 Gene3D G3DSA:3.40.50.7700 1 161 4.2E-73 T 11-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 AFK25_01285 c6d3d8c180039a9b807973b56f1f825a 162 PIRSF PIRSF001338 1 162 1.3E-68 T 11-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 AFK25_01285 c6d3d8c180039a9b807973b56f1f825a 162 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 5 161 4.8E-68 T 11-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFK25_01285 c6d3d8c180039a9b807973b56f1f825a 162 SUPERFAMILY SSF52255 4 161 6.28E-69 T 11-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 AFK25_01285 c6d3d8c180039a9b807973b56f1f825a 162 Pfam PF00731 AIR carboxylase 5 151 3.9E-65 T 11-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFK25_01285 c6d3d8c180039a9b807973b56f1f825a 162 SMART SM01001 3 154 1.1E-103 T 11-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AFK25_09280 bc119d803c9736f24b48ba4b07f7e616 207 Pfam PF13411 MerR HTH family regulatory protein 4 55 8.1E-9 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_09280 bc119d803c9736f24b48ba4b07f7e616 207 SUPERFAMILY SSF53041 60 195 1.01E-22 T 11-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 AFK25_09280 bc119d803c9736f24b48ba4b07f7e616 207 Pfam PF00239 Resolvase, N terminal domain 62 193 8.5E-20 T 11-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFK25_09280 bc119d803c9736f24b48ba4b07f7e616 207 SMART SM00857 62 198 1.6E-19 T 11-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFK25_09280 bc119d803c9736f24b48ba4b07f7e616 207 Gene3D G3DSA:1.10.1660.10 1 61 2.3E-13 T 11-10-2018 AFK25_09280 bc119d803c9736f24b48ba4b07f7e616 207 ProSitePatterns PS00397 Site-specific recombinases active site. 65 73 - T 11-10-2018 IPR006118 Recombinase, conserved site GO:0000150|GO:0006310 AFK25_09280 bc119d803c9736f24b48ba4b07f7e616 207 SUPERFAMILY SSF46955 3 57 1.42E-12 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily AFK25_09280 bc119d803c9736f24b48ba4b07f7e616 207 SMART SM00422 4 80 7.5E-5 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_09280 bc119d803c9736f24b48ba4b07f7e616 207 Gene3D G3DSA:3.40.50.1390 62 159 2.7E-25 T 11-10-2018 AFK25_09480 8b27d8585c8e56524396565c067e597b 227 TIGRFAM TIGR00351 narI: respiratory nitrate reductase, gamma subunit 2 222 4.7E-85 T 11-10-2018 IPR003816 Nitrate reductase, gamma subunit GO:0008940|GO:0009325|GO:0055114 AFK25_09480 8b27d8585c8e56524396565c067e597b 227 Pfam PF02665 Nitrate reductase gamma subunit 4 222 1.2E-86 T 11-10-2018 IPR023234 NarG-like domain AFK25_09480 8b27d8585c8e56524396565c067e597b 227 Gene3D G3DSA:1.20.950.20 1 214 1.5E-80 T 11-10-2018 AFK25_09480 8b27d8585c8e56524396565c067e597b 227 SUPERFAMILY SSF103501 2 222 2.09E-70 T 11-10-2018 IPR036197 NarG-like superfamily AFK25_07150 ff634750a23346a8842db0505247b410 369 Pfam PF01924 Hydrogenase formation hypA family 21 365 9.8E-137 T 11-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 AFK25_07150 ff634750a23346a8842db0505247b410 369 Gene3D G3DSA:3.40.50.11740 67 304 9.4E-102 T 11-10-2018 AFK25_07150 ff634750a23346a8842db0505247b410 369 PIRSF PIRSF005622 3 369 6.3E-135 T 11-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 AFK25_07150 ff634750a23346a8842db0505247b410 369 Gene3D G3DSA:3.40.50.11750 31 264 9.4E-102 T 11-10-2018 AFK25_07150 ff634750a23346a8842db0505247b410 369 Gene3D G3DSA:1.10.10.2140 317 367 3.6E-25 T 11-10-2018 AFK25_07150 ff634750a23346a8842db0505247b410 369 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 16 368 3.1E-120 T 11-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 AFK25_06585 5575e604d6690895052d6887b10d4502 555 Pfam PF17392 Urocanase C-terminal domain 350 544 5.8E-96 T 11-10-2018 IPR035401 Urocanase, C-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFK25_06585 5575e604d6690895052d6887b10d4502 555 Gene3D G3DSA:3.40.1770.10 18 540 4.4E-261 T 11-10-2018 AFK25_06585 5575e604d6690895052d6887b10d4502 555 TIGRFAM TIGR01228 hutU: urocanate hydratase 9 552 0.0 T 11-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFK25_06585 5575e604d6690895052d6887b10d4502 555 Hamap MF_00577 Urocanate hydratase [hutU]. 2 554 51.983 T 11-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFK25_06585 5575e604d6690895052d6887b10d4502 555 Gene3D G3DSA:3.40.50.10730 140 347 4.4E-261 T 11-10-2018 IPR038364 Urocanase, central domain superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFK25_06585 5575e604d6690895052d6887b10d4502 555 PIRSF PIRSF001423 2 555 5.0E-301 T 11-10-2018 IPR023637 Urocanase GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFK25_06585 5575e604d6690895052d6887b10d4502 555 SUPERFAMILY SSF111326 7 553 2.88E-263 T 11-10-2018 IPR036190 Urocanase superfamily KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFK25_06585 5575e604d6690895052d6887b10d4502 555 Pfam PF17391 Urocanase N-terminal domain 10 136 4.4E-62 T 11-10-2018 IPR035400 Urocanase, N-terminal domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFK25_06585 5575e604d6690895052d6887b10d4502 555 Pfam PF01175 Urocanase Rossmann-like domain 139 347 8.7E-94 T 11-10-2018 IPR035085 Urocanase, Rossmann-like domain KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFK25_06585 5575e604d6690895052d6887b10d4502 555 ProSitePatterns PS01233 Urocanase signature. 440 455 - T 11-10-2018 IPR023636 Urocanase conserved site GO:0016153 KEGG: 00340+4.2.1.49|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFK25_08590 a856176600a772b58e10564fdb44fbae 255 Hamap MF_00835 Malonyl-[acyl-carrier protein] O-methyltransferase [bioC]. 2 252 27.413 T 11-10-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00780+2.1.1.197|MetaCyc: PWY-6519 AFK25_08590 a856176600a772b58e10564fdb44fbae 255 Gene3D G3DSA:3.40.50.150 3 209 1.3E-37 T 11-10-2018 AFK25_08590 a856176600a772b58e10564fdb44fbae 255 TIGRFAM TIGR02072 BioC: malonyl-acyl carrier protein O-methyltransferase BioC 10 252 9.7E-62 T 11-10-2018 IPR011814 Malonyl-[acyl-carrier protein] O-methyltransferase BioC GO:0009102|GO:0010340 KEGG: 00780+2.1.1.197|MetaCyc: PWY-6519 AFK25_08590 a856176600a772b58e10564fdb44fbae 255 SUPERFAMILY SSF53335 10 198 1.67E-35 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_08590 a856176600a772b58e10564fdb44fbae 255 Pfam PF08241 Methyltransferase domain 44 138 1.7E-17 T 11-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 Pfam PF01751 Toprim domain 426 531 5.4E-16 T 11-10-2018 IPR006171 TOPRIM domain AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 Hamap MF_00939 DNA topoisomerase 4 subunit B [parE]. 9 641 48.289 T 11-10-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 SMART SM00433 40 636 0.0 T 11-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 Pfam PF00204 DNA gyrase B 225 395 2.3E-56 T 11-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 SUPERFAMILY SSF56719 401 641 4.45E-85 T 11-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 TIGRFAM TIGR01058 parE_Gpos: DNA topoisomerase IV, B subunit 10 645 0.0 T 11-10-2018 IPR005740 DNA topoisomerase 4 subunit B, Firmicutes/Mollicutes GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 Gene3D G3DSA:3.30.565.10 9 223 1.2E-88 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 571 632 8.2E-31 T 11-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 36 179 1.0E-22 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 SUPERFAMILY SSF54211 225 395 1.9E-52 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 PRINTS PR00418 DNA topoisomerase II family signature 40 55 1.4E-69 T 11-10-2018 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 PRINTS PR00418 DNA topoisomerase II family signature 75 88 1.4E-69 T 11-10-2018 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 PRINTS PR00418 DNA topoisomerase II family signature 271 284 1.4E-69 T 11-10-2018 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 PRINTS PR00418 DNA topoisomerase II family signature 493 509 1.4E-69 T 11-10-2018 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 PRINTS PR00418 DNA topoisomerase II family signature 531 543 1.4E-69 T 11-10-2018 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 PRINTS PR00418 DNA topoisomerase II family signature 511 528 1.4E-69 T 11-10-2018 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 PRINTS PR00418 DNA topoisomerase II family signature 575 591 1.4E-69 T 11-10-2018 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 PRINTS PR00418 DNA topoisomerase II family signature 117 131 1.4E-69 T 11-10-2018 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 PRINTS PR00418 DNA topoisomerase II family signature 427 441 1.4E-69 T 11-10-2018 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 Gene3D G3DSA:3.30.230.10 224 405 5.8E-71 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 PRINTS PR01159 DNA gyrase subunit B signature 185 200 2.3E-60 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 PRINTS PR01159 DNA gyrase subunit B signature 224 246 2.3E-60 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 PRINTS PR01159 DNA gyrase subunit B signature 477 486 2.3E-60 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 PRINTS PR01159 DNA gyrase subunit B signature 365 379 2.3E-60 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 PRINTS PR01159 DNA gyrase subunit B signature 11 21 2.3E-60 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 PRINTS PR01159 DNA gyrase subunit B signature 612 628 2.3E-60 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 PRINTS PR01159 DNA gyrase subunit B signature 596 608 2.3E-60 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 PRINTS PR01159 DNA gyrase subunit B signature 200 213 2.3E-60 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 PRINTS PR01159 DNA gyrase subunit B signature 379 399 2.3E-60 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 PRINTS PR01159 DNA gyrase subunit B signature 315 331 2.3E-60 T 11-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 ProSitePatterns PS00177 DNA topoisomerase II signature. 429 437 - T 11-10-2018 IPR018522 DNA topoisomerase, type IIA, conserved site GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 SMART SM00387 36 180 9.6E-28 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 Gene3D G3DSA:3.40.50.670 413 645 9.4E-102 T 11-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFK25_07215 954e1d1f330adfb2304d0b0af449b96f 657 SUPERFAMILY SSF55874 11 222 2.75E-71 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_06285 58ff1585c92d7e434d31183eae195956 88 SUPERFAMILY SSF56281 38 84 6.81E-11 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_06285 58ff1585c92d7e434d31183eae195956 88 Gene3D G3DSA:3.60.15.10 4 88 5.4E-11 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_06285 58ff1585c92d7e434d31183eae195956 88 Pfam PF00753 Metallo-beta-lactamase superfamily 39 86 4.2E-8 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_00250 18f5b86dcca228c261f8247a403b441a 288 SUPERFAMILY SSF54211 3 157 5.16E-47 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFK25_00250 18f5b86dcca228c261f8247a403b441a 288 Hamap MF_00061 Putative 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase [ispE]. 3 279 36.248 T 11-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 AFK25_00250 18f5b86dcca228c261f8247a403b441a 288 Pfam PF00288 GHMP kinases N terminal domain 87 144 4.4E-11 T 11-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 AFK25_00250 18f5b86dcca228c261f8247a403b441a 288 Pfam PF08544 GHMP kinases C terminal 197 271 3.2E-10 T 11-10-2018 IPR013750 GHMP kinase, C-terminal domain AFK25_00250 18f5b86dcca228c261f8247a403b441a 288 Gene3D G3DSA:3.30.230.10 1 158 8.4E-62 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFK25_00250 18f5b86dcca228c261f8247a403b441a 288 SUPERFAMILY SSF55060 161 281 4.32E-32 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily AFK25_00250 18f5b86dcca228c261f8247a403b441a 288 Gene3D G3DSA:3.30.70.890 163 285 6.4E-28 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily AFK25_00250 18f5b86dcca228c261f8247a403b441a 288 PIRSF PIRSF010376 2 288 6.2E-98 T 11-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 AFK25_00250 18f5b86dcca228c261f8247a403b441a 288 TIGRFAM TIGR00154 ispE: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase 2 286 1.4E-109 T 11-10-2018 IPR004424 4-diphosphocytidyl-2C-methyl-D-erythritol kinase GO:0016114|GO:0050515 KEGG: 00900+2.7.1.148|MetaCyc: PWY-7560 AFK25_00210 ba1d92daab078ab5c60e442b8260f87f 94 Gene3D G3DSA:2.10.260.10 1 51 2.3E-26 T 11-10-2018 AFK25_00210 ba1d92daab078ab5c60e442b8260f87f 94 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 8 50 1.8E-11 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFK25_00210 ba1d92daab078ab5c60e442b8260f87f 94 SMART SM00966 8 51 6.1E-10 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFK25_00210 ba1d92daab078ab5c60e442b8260f87f 94 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 8 49 8.2E-11 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFK25_00210 ba1d92daab078ab5c60e442b8260f87f 94 SUPERFAMILY SSF89447 1 52 1.29E-16 T 11-10-2018 IPR037914 SpoVT-AbrB domain superfamily AFK25_14170 9374f5b437a8b3c8b11882738815a293 460 SUPERFAMILY SSF52954 356 458 2.87E-33 T 11-10-2018 AFK25_14170 9374f5b437a8b3c8b11882738815a293 460 Pfam PF03129 Anticodon binding domain 369 456 5.8E-22 T 11-10-2018 IPR004154 Anticodon-binding AFK25_14170 9374f5b437a8b3c8b11882738815a293 460 Hamap MF_00253_B Glycine--tRNA ligase [glyQS]. 2 459 52.267 T 11-10-2018 IPR022961 Glycine-tRNA ligase, bacterial GO:0004820 KEGG: 00970+6.1.1.14 AFK25_14170 9374f5b437a8b3c8b11882738815a293 460 SUPERFAMILY SSF55681 4 372 2.3E-127 T 11-10-2018 AFK25_14170 9374f5b437a8b3c8b11882738815a293 460 Gene3D G3DSA:3.40.50.800 365 459 1.5E-31 T 11-10-2018 IPR036621 Anticodon-binding domain superfamily AFK25_14170 9374f5b437a8b3c8b11882738815a293 460 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 4 242 4.0E-92 T 11-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFK25_14170 9374f5b437a8b3c8b11882738815a293 460 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 164 339 1.8E-11 T 11-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_14170 9374f5b437a8b3c8b11882738815a293 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 168 185 2.1E-53 T 11-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFK25_14170 9374f5b437a8b3c8b11882738815a293 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 147 159 2.1E-53 T 11-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFK25_14170 9374f5b437a8b3c8b11882738815a293 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 324 336 2.1E-53 T 11-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFK25_14170 9374f5b437a8b3c8b11882738815a293 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 217 227 2.1E-53 T 11-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFK25_14170 9374f5b437a8b3c8b11882738815a293 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 200 217 2.1E-53 T 11-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFK25_14170 9374f5b437a8b3c8b11882738815a293 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 404 423 2.1E-53 T 11-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFK25_14170 9374f5b437a8b3c8b11882738815a293 460 PRINTS PR01043 Glycyl-tRNA synthetase signature 24 38 2.1E-53 T 11-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AFK25_01240 c1702d29a0cb5f932dfae4aa84d04fb7 94 PRINTS PR00297 10kDa chaperonin signature 2 17 2.0E-33 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFK25_01240 c1702d29a0cb5f932dfae4aa84d04fb7 94 PRINTS PR00297 10kDa chaperonin signature 24 45 2.0E-33 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFK25_01240 c1702d29a0cb5f932dfae4aa84d04fb7 94 PRINTS PR00297 10kDa chaperonin signature 59 71 2.0E-33 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFK25_01240 c1702d29a0cb5f932dfae4aa84d04fb7 94 PRINTS PR00297 10kDa chaperonin signature 80 93 2.0E-33 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFK25_01240 c1702d29a0cb5f932dfae4aa84d04fb7 94 SMART SM00883 1 93 1.1E-57 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFK25_01240 c1702d29a0cb5f932dfae4aa84d04fb7 94 Pfam PF00166 Chaperonin 10 Kd subunit 2 93 4.9E-37 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFK25_01240 c1702d29a0cb5f932dfae4aa84d04fb7 94 Hamap MF_00580 10 kDa chaperonin [groS]. 1 94 27.626 T 11-10-2018 IPR020818 GroES chaperonin family GO:0005737|GO:0006457 AFK25_01240 c1702d29a0cb5f932dfae4aa84d04fb7 94 Gene3D G3DSA:2.30.33.40 1 94 4.0E-39 T 11-10-2018 IPR037124 GroES chaperonin superfamily GO:0005737|GO:0006457 AFK25_01240 c1702d29a0cb5f932dfae4aa84d04fb7 94 SUPERFAMILY SSF50129 2 93 7.63E-36 T 11-10-2018 IPR011032 GroES-like superfamily AFK25_01240 c1702d29a0cb5f932dfae4aa84d04fb7 94 ProSitePatterns PS00681 Chaperonins cpn10 signature. 2 26 - T 11-10-2018 IPR018369 Chaperonin GroES, conserved site GO:0005524|GO:0006457 AFK25_05945 15c8b3d16201a11ab2488a7e910cc893 197 PIRSF PIRSF001390 1 195 4.5E-83 T 11-10-2018 IPR014214 Dipicolinic acid synthetase, subunit B AFK25_05945 15c8b3d16201a11ab2488a7e910cc893 197 SUPERFAMILY SSF52507 6 191 1.7E-28 T 11-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AFK25_05945 15c8b3d16201a11ab2488a7e910cc893 197 Gene3D G3DSA:3.40.50.1950 1 197 3.5E-56 T 11-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AFK25_05945 15c8b3d16201a11ab2488a7e910cc893 197 TIGRFAM TIGR02852 spore_dpaB: dipicolinic acid synthetase, B subunit 6 192 9.3E-105 T 11-10-2018 IPR014214 Dipicolinic acid synthetase, subunit B AFK25_05945 15c8b3d16201a11ab2488a7e910cc893 197 Pfam PF02441 Flavoprotein 6 161 9.3E-18 T 11-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AFK25_01295 696cca803929a1cf184630fadd2ba6db 431 Pfam PF00206 Lyase 6 286 1.1E-78 T 11-10-2018 IPR022761 Fumarate lyase, N-terminal AFK25_01295 696cca803929a1cf184630fadd2ba6db 431 PRINTS PR00149 Fumarate lyase superfamily signature 261 277 1.8E-26 T 11-10-2018 IPR000362 Fumarate lyase family AFK25_01295 696cca803929a1cf184630fadd2ba6db 431 PRINTS PR00149 Fumarate lyase superfamily signature 88 106 1.8E-26 T 11-10-2018 IPR000362 Fumarate lyase family AFK25_01295 696cca803929a1cf184630fadd2ba6db 431 PRINTS PR00149 Fumarate lyase superfamily signature 216 243 1.8E-26 T 11-10-2018 IPR000362 Fumarate lyase family AFK25_01295 696cca803929a1cf184630fadd2ba6db 431 PRINTS PR00149 Fumarate lyase superfamily signature 133 151 1.8E-26 T 11-10-2018 IPR000362 Fumarate lyase family AFK25_01295 696cca803929a1cf184630fadd2ba6db 431 ProSitePatterns PS00163 Fumarate lyases signature. 261 270 - T 11-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 AFK25_01295 696cca803929a1cf184630fadd2ba6db 431 Gene3D G3DSA:1.20.200.10 93 348 2.0E-104 T 11-10-2018 AFK25_01295 696cca803929a1cf184630fadd2ba6db 431 SMART SM00998 349 429 4.1E-42 T 11-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFK25_01295 696cca803929a1cf184630fadd2ba6db 431 SUPERFAMILY SSF48557 3 427 9.74E-144 T 11-10-2018 IPR008948 L-Aspartase-like GO:0003824 AFK25_01295 696cca803929a1cf184630fadd2ba6db 431 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 1 428 3.4E-186 T 11-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFK25_01295 696cca803929a1cf184630fadd2ba6db 431 PRINTS PR00145 Argininosuccinate lyase family signature 128 148 3.0E-9 T 11-10-2018 AFK25_01295 696cca803929a1cf184630fadd2ba6db 431 PRINTS PR00145 Argininosuccinate lyase family signature 87 109 3.0E-9 T 11-10-2018 AFK25_01295 696cca803929a1cf184630fadd2ba6db 431 PRINTS PR00145 Argininosuccinate lyase family signature 216 240 3.0E-9 T 11-10-2018 AFK25_01295 696cca803929a1cf184630fadd2ba6db 431 PRINTS PR00145 Argininosuccinate lyase family signature 261 277 3.0E-9 T 11-10-2018 AFK25_01295 696cca803929a1cf184630fadd2ba6db 431 Gene3D G3DSA:1.10.275.10 1 92 4.4E-41 T 11-10-2018 IPR024083 Fumarase/histidase, N-terminal AFK25_01295 696cca803929a1cf184630fadd2ba6db 431 Gene3D G3DSA:1.10.40.30 349 431 5.3E-36 T 11-10-2018 AFK25_01295 696cca803929a1cf184630fadd2ba6db 431 Pfam PF10397 Adenylosuccinate lyase C-terminus 350 427 1.8E-26 T 11-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AFK25_03490 346303dc2a28f1b37027ae19ed52d4d0 136 Gene3D G3DSA:3.40.30.10 1 131 6.2E-47 T 11-10-2018 AFK25_03490 346303dc2a28f1b37027ae19ed52d4d0 136 SUPERFAMILY SSF52833 1 130 2.13E-40 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_03490 346303dc2a28f1b37027ae19ed52d4d0 136 Hamap MF_01132 Regulatory protein Spx [spxA]. 1 131 38.314 T 11-10-2018 IPR023731 Regulatory protein Spx GO:0045892 AFK25_03490 346303dc2a28f1b37027ae19ed52d4d0 136 Pfam PF03960 ArsC family 5 113 3.6E-23 T 11-10-2018 IPR006660 Arsenate reductase-like AFK25_03490 346303dc2a28f1b37027ae19ed52d4d0 136 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 4 114 2.7E-36 T 11-10-2018 IPR006504 Transcriptional regulator Spx/MgsR AFK25_00130 56ebdbdd6090e2393052751e98437066 198 Gene3D G3DSA:3.40.1360.10 77 198 4.5E-51 T 11-10-2018 AFK25_00130 56ebdbdd6090e2393052751e98437066 198 ProSitePatterns PS01300 RecR protein signature. 57 78 - T 11-10-2018 IPR015967 Recombination protein RecR, conserved site GO:0006281|GO:0006310 AFK25_00130 56ebdbdd6090e2393052751e98437066 198 Pfam PF13662 Toprim domain 80 171 2.4E-27 T 11-10-2018 IPR006171 TOPRIM domain AFK25_00130 56ebdbdd6090e2393052751e98437066 198 Hamap MF_00017 Recombination protein RecR [recR]. 1 198 112.622 T 11-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 AFK25_00130 56ebdbdd6090e2393052751e98437066 198 TIGRFAM TIGR00615 recR: recombination protein RecR 2 196 2.7E-91 T 11-10-2018 IPR000093 DNA recombination protein RecR GO:0003677|GO:0006281|GO:0006310 AFK25_00130 56ebdbdd6090e2393052751e98437066 198 Pfam PF02132 RecR protein 40 78 2.1E-16 T 11-10-2018 IPR023628 Recombination protein RecR, C4-type zinc finger AFK25_00130 56ebdbdd6090e2393052751e98437066 198 SUPERFAMILY SSF111304 1 198 4.32E-80 T 11-10-2018 IPR023627 Recombination protein RecR AFK25_00130 56ebdbdd6090e2393052751e98437066 198 SMART SM00493 80 165 1.6E-18 T 11-10-2018 IPR006171 TOPRIM domain AFK25_00130 56ebdbdd6090e2393052751e98437066 198 Gene3D G3DSA:1.10.8.420 1 53 5.4E-20 T 11-10-2018 AFK25_04040 2217923c2b039228845d2841ce9f190c 277 Gene3D G3DSA:2.60.120.10 32 271 1.0E-83 T 11-10-2018 IPR014710 RmlC-like jelly roll fold AFK25_04040 2217923c2b039228845d2841ce9f190c 277 Pfam PF02678 Pirin 38 116 2.8E-24 T 11-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 AFK25_04040 2217923c2b039228845d2841ce9f190c 277 Gene3D G3DSA:2.60.120.10 138 245 1.0E-83 T 11-10-2018 IPR014710 RmlC-like jelly roll fold AFK25_04040 2217923c2b039228845d2841ce9f190c 277 SUPERFAMILY SSF51182 26 276 1.44E-78 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily AFK25_04040 2217923c2b039228845d2841ce9f190c 277 Pfam PF05726 Pirin C-terminal cupin domain 169 276 6.5E-31 T 11-10-2018 IPR008778 Pirin, C-terminal domain Reactome: R-HSA-8935690 AFK25_04040 2217923c2b039228845d2841ce9f190c 277 PIRSF PIRSF006232 8 277 2.1E-78 T 11-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 Pfam PF02190 ATP-dependent protease La (LON) substrate-binding domain 8 199 5.7E-45 T 11-10-2018 IPR003111 Lon, substrate-binding domain AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 Gene3D G3DSA:2.30.130.40 2 113 1.4E-29 T 11-10-2018 AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 Hamap MF_01973 Lon protease [lon]. 9 770 72.182 T 11-10-2018 IPR027543 Lon protease, bacterial GO:0004176|GO:0004252|GO:0005524|GO:0006508|GO:0043565 AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 SUPERFAMILY SSF88697 8 199 7.95E-45 T 11-10-2018 IPR015947 PUA-like superfamily AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 SMART SM00464 8 200 6.2E-64 T 11-10-2018 IPR003111 Lon, substrate-binding domain AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 350 487 6.9E-24 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 Gene3D G3DSA:1.10.8.60 490 582 1.6E-34 T 11-10-2018 AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 SUPERFAMILY SSF52540 310 586 4.75E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 Gene3D G3DSA:3.30.230.10 591 774 7.1E-85 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 Gene3D G3DSA:3.40.50.300 311 489 2.7E-69 T 11-10-2018 AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 701 720 9.2E-54 T 11-10-2018 AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 724 742 9.2E-54 T 11-10-2018 AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 354 373 9.2E-54 T 11-10-2018 AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 671 690 9.2E-54 T 11-10-2018 AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 593 609 9.2E-54 T 11-10-2018 AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 568 770 9.5E-99 T 11-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 SUPERFAMILY SSF54211 593 768 3.72E-56 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 PIRSF PIRSF001174 1 773 0.0 T 11-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 TIGRFAM TIGR00763 lon: endopeptidase La 10 769 0.0 T 11-10-2018 IPR004815 Lon protease, bacterial/eukaryotic-type GO:0004176|GO:0005524|GO:0006508 AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 674 682 - T 11-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 Gene3D G3DSA:1.20.58.1480 118 243 7.6E-40 T 11-10-2018 AFK25_11135 51570398f90452db2fe823dfe7b53fce 774 SMART SM00382 346 491 1.0E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_10745 2aeb83d7d0f9b51b7daf71966fd555ea 592 SUPERFAMILY SSF55261 294 421 1.8E-46 T 11-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 AFK25_10745 2aeb83d7d0f9b51b7daf71966fd555ea 592 TIGRFAM TIGR00459 aspS_bact: aspartate--tRNA ligase 2 584 2.3E-264 T 11-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 AFK25_10745 2aeb83d7d0f9b51b7daf71966fd555ea 592 SUPERFAMILY SSF50249 4 108 3.05E-33 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_10745 2aeb83d7d0f9b51b7daf71966fd555ea 592 Gene3D G3DSA:3.30.1360.30 277 421 8.6E-199 T 11-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 AFK25_10745 2aeb83d7d0f9b51b7daf71966fd555ea 592 Pfam PF02938 GAD domain 313 407 1.4E-33 T 11-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 AFK25_10745 2aeb83d7d0f9b51b7daf71966fd555ea 592 SUPERFAMILY SSF55681 114 583 2.03E-110 T 11-10-2018 AFK25_10745 2aeb83d7d0f9b51b7daf71966fd555ea 592 Gene3D G3DSA:2.40.50.140 1 109 1.1E-35 T 11-10-2018 AFK25_10745 2aeb83d7d0f9b51b7daf71966fd555ea 592 Hamap MF_00044 Aspartate--tRNA(Asp/Asn) ligase [aspS]. 3 586 35.407 T 11-10-2018 IPR004524 Aspartate-tRNA ligase, type 1 GO:0005524|GO:0016874 Reactome: R-HSA-379726 AFK25_10745 2aeb83d7d0f9b51b7daf71966fd555ea 592 Pfam PF01336 OB-fold nucleic acid binding domain 20 105 3.9E-17 T 11-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AFK25_10745 2aeb83d7d0f9b51b7daf71966fd555ea 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 212 225 9.4E-27 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_10745 2aeb83d7d0f9b51b7daf71966fd555ea 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 520 534 9.4E-27 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_10745 2aeb83d7d0f9b51b7daf71966fd555ea 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 476 492 9.4E-27 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_10745 2aeb83d7d0f9b51b7daf71966fd555ea 592 PRINTS PR01042 Aspartyl-tRNA synthetase signature 195 207 9.4E-27 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_10745 2aeb83d7d0f9b51b7daf71966fd555ea 592 Gene3D G3DSA:3.30.930.10 121 583 8.6E-199 T 11-10-2018 AFK25_10745 2aeb83d7d0f9b51b7daf71966fd555ea 592 Pfam PF00152 tRNA synthetases class II (D, K and N) 122 559 3.8E-110 T 11-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_14290 7409423d0d656d26c50c7a3f3cb708b8 233 Gene3D G3DSA:3.40.1280.10 20 226 9.4E-60 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFK25_14290 7409423d0d656d26c50c7a3f3cb708b8 233 Pfam PF00588 SpoU rRNA Methylase family 45 183 1.9E-32 T 11-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AFK25_14290 7409423d0d656d26c50c7a3f3cb708b8 233 SUPERFAMILY SSF75217 25 202 2.94E-41 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases AFK25_14290 7409423d0d656d26c50c7a3f3cb708b8 233 Hamap MF_02060 tRNA (guanosine(18)-2'-O)-methyltransferase [trmH]. 26 218 32.358 T 11-10-2018 IPR033671 tRNA (guanosine(18)-2'-O)-methyltransferase GO:0008168|GO:0030488 AFK25_05590 adb5fd87d91b245680f8c0d81ab18e30 254 Gene3D G3DSA:3.30.420.10 44 254 4.6E-82 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFK25_05590 adb5fd87d91b245680f8c0d81ab18e30 254 Hamap MF_00052_B Ribonuclease HII [rnhB]. 68 246 36.962 T 11-10-2018 IPR022898 Ribonuclease HII GO:0004523 AFK25_05590 adb5fd87d91b245680f8c0d81ab18e30 254 Pfam PF01351 Ribonuclease HII 70 244 1.2E-38 T 11-10-2018 IPR024567 Ribonuclease HII/HIII domain AFK25_05590 adb5fd87d91b245680f8c0d81ab18e30 254 SUPERFAMILY SSF53098 57 251 6.07E-71 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_06800 bfd741a679b0f6ee237bce38753d9c73 74 SUPERFAMILY SSF50182 6 64 1.27E-24 T 11-10-2018 IPR010920 LSM domain superfamily AFK25_06800 bfd741a679b0f6ee237bce38753d9c73 74 Hamap MF_00436 RNA-binding protein Hfq [hfq]. 1 65 29.761 T 11-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 AFK25_06800 bfd741a679b0f6ee237bce38753d9c73 74 TIGRFAM TIGR02383 Hfq: RNA chaperone Hfq 6 65 1.8E-32 T 11-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 AFK25_06800 bfd741a679b0f6ee237bce38753d9c73 74 Gene3D G3DSA:2.30.30.100 1 74 6.2E-35 T 11-10-2018 AFK25_06800 bfd741a679b0f6ee237bce38753d9c73 74 Pfam PF17209 Hfq protein 7 70 3.4E-33 T 11-10-2018 IPR005001 RNA-binding protein Hfq GO:0003723|GO:0006355 AFK25_06930 dfd8de57b72cf7ed027236d363778303 902 SUPERFAMILY SSF53732 5 636 1.44E-232 T 11-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 AFK25_06930 dfd8de57b72cf7ed027236d363778303 902 Gene3D G3DSA:3.30.499.10 376 599 2.1E-103 T 11-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 AFK25_06930 dfd8de57b72cf7ed027236d363778303 902 PRINTS PR00415 Aconitase family signature 281 294 1.1E-42 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFK25_06930 dfd8de57b72cf7ed027236d363778303 902 PRINTS PR00415 Aconitase family signature 295 308 1.1E-42 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFK25_06930 dfd8de57b72cf7ed027236d363778303 902 PRINTS PR00415 Aconitase family signature 375 389 1.1E-42 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFK25_06930 dfd8de57b72cf7ed027236d363778303 902 PRINTS PR00415 Aconitase family signature 502 515 1.1E-42 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFK25_06930 dfd8de57b72cf7ed027236d363778303 902 PRINTS PR00415 Aconitase family signature 147 160 1.1E-42 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFK25_06930 dfd8de57b72cf7ed027236d363778303 902 PRINTS PR00415 Aconitase family signature 440 451 1.1E-42 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFK25_06930 dfd8de57b72cf7ed027236d363778303 902 PRINTS PR00415 Aconitase family signature 171 179 1.1E-42 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFK25_06930 dfd8de57b72cf7ed027236d363778303 902 PRINTS PR00415 Aconitase family signature 205 218 1.1E-42 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFK25_06930 dfd8de57b72cf7ed027236d363778303 902 PRINTS PR00415 Aconitase family signature 219 234 1.1E-42 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFK25_06930 dfd8de57b72cf7ed027236d363778303 902 Pfam PF00330 Aconitase family (aconitate hydratase) 78 571 7.6E-180 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFK25_06930 dfd8de57b72cf7ed027236d363778303 902 TIGRFAM TIGR01341 aconitase_1: aconitate hydratase 1 18 900 0.0 T 11-10-2018 IPR006249 Aconitase/Iron-responsive element-binding protein 2 KEGG: 00020+4.2.1.3|KEGG: 00630+4.2.1.3|KEGG: 00720+4.2.1.3|Reactome: R-HSA-917937 AFK25_06930 dfd8de57b72cf7ed027236d363778303 902 SUPERFAMILY SSF52016 640 899 9.81E-89 T 11-10-2018 AFK25_06930 dfd8de57b72cf7ed027236d363778303 902 ProSitePatterns PS00450 Aconitase family signature 1. 436 452 - T 11-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFK25_06930 dfd8de57b72cf7ed027236d363778303 902 Gene3D G3DSA:3.20.19.10 662 901 5.6E-104 T 11-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 AFK25_06930 dfd8de57b72cf7ed027236d363778303 902 ProSitePatterns PS01244 Aconitase family signature 2. 502 515 - T 11-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFK25_06930 dfd8de57b72cf7ed027236d363778303 902 Pfam PF00694 Aconitase C-terminal domain 701 828 1.5E-46 T 11-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 AFK25_06930 dfd8de57b72cf7ed027236d363778303 902 Gene3D G3DSA:1.10.1440.20 600 660 1.3E-23 T 11-10-2018 AFK25_06930 dfd8de57b72cf7ed027236d363778303 902 Gene3D G3DSA:3.30.499.20 5 375 2.0E-161 T 11-10-2018 AFK25_10820 64110954da28c287d24e7fe45031c0dc 379 Pfam PF01702 Queuine tRNA-ribosyltransferase 132 365 5.9E-93 T 11-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFK25_10820 64110954da28c287d24e7fe45031c0dc 379 SUPERFAMILY SSF51713 4 369 5.89E-162 T 11-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFK25_10820 64110954da28c287d24e7fe45031c0dc 379 Gene3D G3DSA:3.20.20.105 2 372 4.1E-170 T 11-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFK25_10820 64110954da28c287d24e7fe45031c0dc 379 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 6 371 6.0E-185 T 11-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFK25_10820 64110954da28c287d24e7fe45031c0dc 379 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 6 371 2.3E-174 T 11-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFK25_10820 64110954da28c287d24e7fe45031c0dc 379 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 4 368 57.709 T 11-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AFK25_02185 003defd5fc209b5a6a03f91333e83cf4 202 Pfam PF01841 Transglutaminase-like superfamily 34 138 1.0E-10 T 11-10-2018 IPR002931 Transglutaminase-like AFK25_02185 003defd5fc209b5a6a03f91333e83cf4 202 SUPERFAMILY SSF54001 22 142 3.5E-20 T 11-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFK25_02185 003defd5fc209b5a6a03f91333e83cf4 202 Gene3D G3DSA:3.10.620.30 2 166 2.2E-15 T 11-10-2018 AFK25_00615 0a32e2142eeeef2097bff21bc158020e 95 Gene3D G3DSA:3.30.70.330 1 95 3.0E-33 T 11-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily AFK25_00615 0a32e2142eeeef2097bff21bc158020e 95 Hamap MF_01369_B 50S ribosomal protein L23 [rplW]. 5 95 21.75 T 11-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 AFK25_00615 0a32e2142eeeef2097bff21bc158020e 95 SUPERFAMILY SSF54189 2 90 3.09E-32 T 11-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00615 0a32e2142eeeef2097bff21bc158020e 95 ProSitePatterns PS00050 Ribosomal protein L23 signature. 77 92 - T 11-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00615 0a32e2142eeeef2097bff21bc158020e 95 Pfam PF00276 Ribosomal protein L23 6 88 1.0E-32 T 11-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 AFK25_12810 0b02dd523091af565cc4fed26e4d15fc 792 SUPERFAMILY SSF48179 204 322 5.7E-22 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFK25_12810 0b02dd523091af565cc4fed26e4d15fc 792 Gene3D G3DSA:1.10.1040.10 362 434 5.7E-8 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFK25_12810 0b02dd523091af565cc4fed26e4d15fc 792 Pfam PF00378 Enoyl-CoA hydratase/isomerase 487 620 2.2E-9 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFK25_12810 0b02dd523091af565cc4fed26e4d15fc 792 SUPERFAMILY SSF52096 481 789 2.62E-37 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFK25_12810 0b02dd523091af565cc4fed26e4d15fc 792 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 203 5.9E-45 T 11-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFK25_12810 0b02dd523091af565cc4fed26e4d15fc 792 Gene3D G3DSA:1.10.1040.10 207 326 2.3E-18 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFK25_12810 0b02dd523091af565cc4fed26e4d15fc 792 Gene3D G3DSA:3.40.50.720 1 206 4.4E-66 T 11-10-2018 AFK25_12810 0b02dd523091af565cc4fed26e4d15fc 792 SUPERFAMILY SSF51735 1 204 4.35E-43 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_12810 0b02dd523091af565cc4fed26e4d15fc 792 Gene3D G3DSA:3.90.226.10 483 670 6.5E-29 T 11-10-2018 AFK25_12810 0b02dd523091af565cc4fed26e4d15fc 792 SUPERFAMILY SSF48179 355 454 6.8E-20 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFK25_12810 0b02dd523091af565cc4fed26e4d15fc 792 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 362 431 1.1E-4 T 11-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFK25_12810 0b02dd523091af565cc4fed26e4d15fc 792 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 206 303 1.3E-10 T 11-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFK25_11835 0cbf2a497c56a856efe0094f1cbc8404 615 SUPERFAMILY SSF55781 287 448 3.49E-9 T 11-10-2018 AFK25_11835 0cbf2a497c56a856efe0094f1cbc8404 615 Pfam PF00990 Diguanylate cyclase, GGDEF domain 462 609 1.2E-41 T 11-10-2018 IPR000160 GGDEF domain AFK25_11835 0cbf2a497c56a856efe0094f1cbc8404 615 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 457 613 1.4E-42 T 11-10-2018 IPR000160 GGDEF domain AFK25_11835 0cbf2a497c56a856efe0094f1cbc8404 615 Gene3D G3DSA:3.30.70.270 455 614 2.0E-48 T 11-10-2018 AFK25_11835 0cbf2a497c56a856efe0094f1cbc8404 615 SUPERFAMILY SSF55073 466 612 9.42E-42 T 11-10-2018 IPR029787 Nucleotide cyclase AFK25_11835 0cbf2a497c56a856efe0094f1cbc8404 615 SUPERFAMILY SSF55781 159 317 6.32E-14 T 11-10-2018 AFK25_11835 0cbf2a497c56a856efe0094f1cbc8404 615 Gene3D G3DSA:3.30.450.40 306 454 6.7E-8 T 11-10-2018 IPR029016 GAF-like domain superfamily AFK25_11835 0cbf2a497c56a856efe0094f1cbc8404 615 SMART SM00267 450 613 1.6E-56 T 11-10-2018 IPR000160 GGDEF domain AFK25_11835 0cbf2a497c56a856efe0094f1cbc8404 615 Gene3D G3DSA:3.30.450.40 162 304 4.6E-11 T 11-10-2018 IPR029016 GAF-like domain superfamily AFK25_05280 bba54897139c92c66a4dbd64c89b253c 80 SUPERFAMILY SSF50346 1 74 6.54E-14 T 11-10-2018 IPR011033 PRC-barrel-like superfamily AFK25_05280 bba54897139c92c66a4dbd64c89b253c 80 Gene3D G3DSA:2.30.30.240 1 77 9.6E-13 T 11-10-2018 AFK25_05280 bba54897139c92c66a4dbd64c89b253c 80 Pfam PF05239 PRC-barrel domain 2 78 7.3E-14 T 11-10-2018 IPR027275 PRC-barrel domain AFK25_05280 bba54897139c92c66a4dbd64c89b253c 80 TIGRFAM TIGR02888 spore_YlmC_YmxH: sporulation protein, YlmC/YmxH family 3 75 1.1E-26 T 11-10-2018 IPR014238 Sporulation protein YlmC/YmxH AFK25_09070 f4c1098b457f5d0aa5681878ac6362cd 228 Pfam PF02585 GlcNAc-PI de-N-acetylase 6 135 3.0E-27 T 11-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 AFK25_09070 f4c1098b457f5d0aa5681878ac6362cd 228 SUPERFAMILY SSF102588 1 198 1.96E-43 T 11-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 AFK25_09070 f4c1098b457f5d0aa5681878ac6362cd 228 Gene3D G3DSA:3.40.50.10320 1 217 5.3E-41 T 11-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 AFK25_09955 d9d399c8d38d63a88199e40bbc61b68c 853 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 128 776 1.4E-184 T 11-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFK25_09955 d9d399c8d38d63a88199e40bbc61b68c 853 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 130 179 1.4E-7 T 11-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_09955 d9d399c8d38d63a88199e40bbc61b68c 853 SUPERFAMILY SSF51998 126 836 4.88E-149 T 11-10-2018 AFK25_09955 d9d399c8d38d63a88199e40bbc61b68c 853 Gene3D G3DSA:3.20.70.20 346 781 3.8E-124 T 11-10-2018 AFK25_09955 d9d399c8d38d63a88199e40bbc61b68c 853 Gene3D G3DSA:3.20.70.20 115 301 1.9E-42 T 11-10-2018 AFK25_09955 d9d399c8d38d63a88199e40bbc61b68c 853 Pfam PF02867 Ribonucleotide reductase, barrel domain 187 766 3.1E-126 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_09955 d9d399c8d38d63a88199e40bbc61b68c 853 PRINTS PR01183 Ribonucleotide reductase large chain signature 262 281 4.2E-36 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_09955 d9d399c8d38d63a88199e40bbc61b68c 853 PRINTS PR01183 Ribonucleotide reductase large chain signature 638 665 4.2E-36 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_09955 d9d399c8d38d63a88199e40bbc61b68c 853 PRINTS PR01183 Ribonucleotide reductase large chain signature 507 530 4.2E-36 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_09955 d9d399c8d38d63a88199e40bbc61b68c 853 PRINTS PR01183 Ribonucleotide reductase large chain signature 545 567 4.2E-36 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_09955 d9d399c8d38d63a88199e40bbc61b68c 853 PRINTS PR01183 Ribonucleotide reductase large chain signature 573 596 4.2E-36 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_03740 ea34926f3e5ca584796d51dd83cb5175 171 Pfam PF04608 Phosphatidylglycerophosphatase A 15 157 6.4E-18 T 11-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 AFK25_03740 ea34926f3e5ca584796d51dd83cb5175 171 PIRSF PIRSF019587 4 168 5.3E-65 T 11-10-2018 IPR026038 Putative phosphatidylglycerophosphatase AFK25_03740 ea34926f3e5ca584796d51dd83cb5175 171 Gene3D G3DSA:1.10.3760.10 3 170 4.2E-69 T 11-10-2018 AFK25_03740 ea34926f3e5ca584796d51dd83cb5175 171 SUPERFAMILY SSF101307 8 161 3.4E-48 T 11-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 AFK25_13580 1be7a47fc61bf12f1eca601609c5b2d2 360 Pfam PF04230 Polysaccharide pyruvyl transferase 13 288 2.0E-57 T 11-10-2018 IPR007345 Polysaccharide pyruvyl transferase AFK25_13580 1be7a47fc61bf12f1eca601609c5b2d2 360 SUPERFAMILY SSF53756 11 284 4.4E-12 T 11-10-2018 AFK25_13580 1be7a47fc61bf12f1eca601609c5b2d2 360 TIGRFAM TIGR03609 S_layer_CsaB: polysaccharide pyruvyl transferase CsaB 3 307 9.7E-98 T 11-10-2018 IPR019896 Polysaccharide pyruvyl transferase, CsaB AFK25_11930 9e9d9fc574bf2c7e0ecdd65c792413a2 268 PIRSF PIRSF012562 1 265 1.3E-129 T 11-10-2018 IPR010838 Protein of unknown unction DUF1444 AFK25_11930 9e9d9fc574bf2c7e0ecdd65c792413a2 268 Pfam PF07285 Protein of unknown function (DUF1444) 1 264 1.8E-132 T 11-10-2018 IPR010838 Protein of unknown unction DUF1444 AFK25_11930 9e9d9fc574bf2c7e0ecdd65c792413a2 268 Hamap MF_01548 UPF0354 protein . 1 265 47.491 T 11-10-2018 IPR010838 Protein of unknown unction DUF1444 AFK25_07305 ba930f133c85577d6a36acdcaafe944a 693 SMART SM00437 259 517 7.2E-79 T 11-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 AFK25_07305 ba930f133c85577d6a36acdcaafe944a 693 Gene3D G3DSA:1.10.290.10 268 398 1.8E-131 T 11-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 AFK25_07305 ba930f133c85577d6a36acdcaafe944a 693 Pfam PF01131 DNA topoisomerase 152 552 4.7E-130 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFK25_07305 ba930f133c85577d6a36acdcaafe944a 693 SMART SM00436 125 215 4.1E-35 T 11-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 AFK25_07305 ba930f133c85577d6a36acdcaafe944a 693 Gene3D G3DSA:1.10.460.10 159 561 1.8E-131 T 11-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 AFK25_07305 ba930f133c85577d6a36acdcaafe944a 693 Pfam PF01751 Toprim domain 4 128 4.1E-12 T 11-10-2018 IPR006171 TOPRIM domain AFK25_07305 ba930f133c85577d6a36acdcaafe944a 693 SUPERFAMILY SSF56712 1 591 6.41E-174 T 11-10-2018 IPR023405 DNA topoisomerase, type IA, core domain AFK25_07305 ba930f133c85577d6a36acdcaafe944a 693 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 302 311 3.6E-29 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFK25_07305 ba930f133c85577d6a36acdcaafe944a 693 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 99 112 3.6E-29 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFK25_07305 ba930f133c85577d6a36acdcaafe944a 693 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 480 494 3.6E-29 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFK25_07305 ba930f133c85577d6a36acdcaafe944a 693 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 185 203 3.6E-29 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFK25_07305 ba930f133c85577d6a36acdcaafe944a 693 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 384 400 3.6E-29 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFK25_07305 ba930f133c85577d6a36acdcaafe944a 693 SMART SM00493 2 125 2.2E-19 T 11-10-2018 IPR006171 TOPRIM domain AFK25_07305 ba930f133c85577d6a36acdcaafe944a 693 Gene3D G3DSA:2.70.20.10 209 464 1.8E-131 T 11-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 AFK25_07305 ba930f133c85577d6a36acdcaafe944a 693 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 672 4.8E-200 T 11-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 AFK25_07305 ba930f133c85577d6a36acdcaafe944a 693 Gene3D G3DSA:3.40.50.140 2 153 4.2E-50 T 11-10-2018 AFK25_07305 ba930f133c85577d6a36acdcaafe944a 693 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 296 311 - T 11-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 AFK25_12475 e8e9797be0a73093508d7ba55135f93c 323 Gene3D G3DSA:3.40.50.720 113 259 5.4E-23 T 11-10-2018 AFK25_12475 e8e9797be0a73093508d7ba55135f93c 323 SUPERFAMILY SSF81324 11 130 2.62E-21 T 11-10-2018 AFK25_12475 e8e9797be0a73093508d7ba55135f93c 323 Pfam PF07885 Ion channel 23 95 1.4E-13 T 11-10-2018 IPR013099 Potassium channel domain AFK25_12475 e8e9797be0a73093508d7ba55135f93c 323 Gene3D G3DSA:1.10.287.70 2 99 1.3E-17 T 11-10-2018 AFK25_12475 e8e9797be0a73093508d7ba55135f93c 323 SUPERFAMILY SSF51735 115 247 1.87E-18 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_12475 e8e9797be0a73093508d7ba55135f93c 323 Pfam PF02254 TrkA-N domain 117 234 1.2E-13 T 11-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AFK25_11385 2708c880744a5b3ef1ee606a6448cb68 174 Gene3D G3DSA:3.30.1060.10 1 160 7.5E-67 T 11-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFK25_11385 2708c880744a5b3ef1ee606a6448cb68 174 Pfam PF01625 Peptide methionine sulfoxide reductase 3 154 2.7E-62 T 11-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFK25_11385 2708c880744a5b3ef1ee606a6448cb68 174 SUPERFAMILY SSF55068 1 165 5.49E-73 T 11-10-2018 IPR036509 Peptide methionine sulphoxide reductase MsrA superfamily GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFK25_11385 2708c880744a5b3ef1ee606a6448cb68 174 TIGRFAM TIGR00401 msrA: peptide-methionine (S)-S-oxide reductase 2 153 4.2E-63 T 11-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFK25_11385 2708c880744a5b3ef1ee606a6448cb68 174 Hamap MF_01401 Peptide methionine sulfoxide reductase MsrA [msrA]. 1 160 37.569 T 11-10-2018 IPR002569 Peptide methionine sulphoxide reductase MsrA GO:0008113|GO:0055114 Reactome: R-HSA-5676934 AFK25_06360 aecc95d1147edb71df5808a5f7952240 105 Pfam PF01906 Putative heavy-metal-binding 1 103 2.5E-39 T 11-10-2018 IPR002765 Uncharacterised protein family UPF0145 AFK25_06360 aecc95d1147edb71df5808a5f7952240 105 Gene3D G3DSA:3.30.110.70 1 105 1.2E-43 T 11-10-2018 AFK25_06360 aecc95d1147edb71df5808a5f7952240 105 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 1 103 24.808 T 11-10-2018 IPR002765 Uncharacterised protein family UPF0145 AFK25_06360 aecc95d1147edb71df5808a5f7952240 105 SUPERFAMILY SSF117782 1 104 1.44E-37 T 11-10-2018 IPR035439 UPF0145 domain superfamily AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 PRINTS PR00301 70kDa heat shock protein signature 358 377 2.3E-80 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 PRINTS PR00301 70kDa heat shock protein signature 172 182 2.3E-80 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 PRINTS PR00301 70kDa heat shock protein signature 304 320 2.3E-80 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 PRINTS PR00301 70kDa heat shock protein signature 3 16 2.3E-80 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 PRINTS PR00301 70kDa heat shock protein signature 112 132 2.3E-80 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 PRINTS PR00301 70kDa heat shock protein signature 335 355 2.3E-80 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 PRINTS PR00301 70kDa heat shock protein signature 439 455 2.3E-80 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 PRINTS PR00301 70kDa heat shock protein signature 53 61 2.3E-80 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 PRINTS PR00301 70kDa heat shock protein signature 31 43 2.3E-80 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 Hamap MF_00332 Chaperone protein DnaK [dnaK]. 1 601 38.157 T 11-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 ProSitePatterns PS00297 Heat shock hsp70 proteins family signature 1. 7 14 - T 11-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 ProSitePatterns PS01036 Heat shock hsp70 proteins family signature 3. 307 321 - T 11-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 SUPERFAMILY SSF53067 1 157 3.72E-60 T 11-10-2018 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 Gene3D G3DSA:1.20.1270.10 494 577 2.7E-20 T 11-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 Gene3D G3DSA:3.90.640.10 198 279 1.9E-160 T 11-10-2018 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 TIGRFAM TIGR02350 prok_dnaK: chaperone protein DnaK 3 573 5.9E-295 T 11-10-2018 IPR012725 Chaperone DnaK GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-1268020|Reactome: R-HSA-3371453|Reactome: R-HSA-8949613|Reactome: R-HSA-8950505 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 Gene3D G3DSA:3.30.420.40 159 337 1.9E-160 T 11-10-2018 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 SUPERFAMILY SSF100934 477 581 1.83E-15 T 11-10-2018 IPR029048 Heat shock protein 70kD, C-terminal domain superfamily Reactome: R-HSA-3371453 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 Pfam PF00012 Hsp70 protein 76 573 3.0E-228 T 11-10-2018 IPR013126 Heat shock protein 70 family Reactome: R-HSA-3371453 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 Gene3D G3DSA:2.60.34.10 353 493 2.1E-68 T 11-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 Gene3D G3DSA:3.30.420.40 5 347 1.9E-160 T 11-10-2018 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 ProSitePatterns PS00329 Heat shock hsp70 proteins family signature 2. 166 179 - T 11-10-2018 IPR018181 Heat shock protein 70, conserved site Reactome: R-HSA-3371453 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 SUPERFAMILY SSF100920 354 510 1.96E-64 T 11-10-2018 IPR029047 Heat shock protein 70kD, peptide-binding domain superfamily Reactome: R-HSA-3371453 AFK25_10380 06bba6ea8849ea4efe0a464a8b051c66 605 SUPERFAMILY SSF53067 160 351 3.18E-70 T 11-10-2018 AFK25_11655 0e48bece40ed534e8f13979c4989fe5e 200 Gene3D G3DSA:1.10.10.10 6 132 1.9E-22 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_11655 0e48bece40ed534e8f13979c4989fe5e 200 SMART SM00345 10 69 6.4E-18 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_11655 0e48bece40ed534e8f13979c4989fe5e 200 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 29 43 1.3E-9 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_11655 0e48bece40ed534e8f13979c4989fe5e 200 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 43 59 1.3E-9 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_11655 0e48bece40ed534e8f13979c4989fe5e 200 Pfam PF00392 Bacterial regulatory proteins, gntR family 13 68 1.3E-17 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_11655 0e48bece40ed534e8f13979c4989fe5e 200 SUPERFAMILY SSF46785 5 73 6.34E-20 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_11655 0e48bece40ed534e8f13979c4989fe5e 200 SUPERFAMILY SSF48008 91 192 2.09E-6 T 11-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFK25_14020 5a508f0266696f917d17f8d1483ee61a 393 SUPERFAMILY SSF53901 271 392 8.47E-38 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_14020 5a508f0266696f917d17f8d1483ee61a 393 Gene3D G3DSA:3.40.47.10 126 390 2.7E-147 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_14020 5a508f0266696f917d17f8d1483ee61a 393 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 391 3.4E-143 T 11-10-2018 IPR002155 Thiolase GO:0016747 AFK25_14020 5a508f0266696f917d17f8d1483ee61a 393 ProSitePatterns PS00737 Thiolases signature 2. 339 355 - T 11-10-2018 IPR020613 Thiolase, conserved site GO:0016747 AFK25_14020 5a508f0266696f917d17f8d1483ee61a 393 SUPERFAMILY SSF53901 4 270 5.92E-84 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_14020 5a508f0266696f917d17f8d1483ee61a 393 Gene3D G3DSA:3.40.47.10 5 276 2.7E-147 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_14020 5a508f0266696f917d17f8d1483ee61a 393 PIRSF PIRSF000429 1 393 2.8E-124 T 11-10-2018 IPR002155 Thiolase GO:0016747 AFK25_14020 5a508f0266696f917d17f8d1483ee61a 393 ProSitePatterns PS00099 Thiolases active site. 374 387 - T 11-10-2018 IPR020610 Thiolase, active site GO:0016747 AFK25_14020 5a508f0266696f917d17f8d1483ee61a 393 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 84 102 - T 11-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 AFK25_14020 5a508f0266696f917d17f8d1483ee61a 393 Pfam PF00108 Thiolase, N-terminal domain 5 263 2.6E-97 T 11-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFK25_14020 5a508f0266696f917d17f8d1483ee61a 393 Pfam PF02803 Thiolase, C-terminal domain 270 391 6.2E-45 T 11-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 AFK25_00600 306bfb28053cab2510edb79c15fe8642 102 SUPERFAMILY SSF54999 5 102 5.1E-39 T 11-10-2018 IPR036838 Ribosomal protein S10 domain superfamily AFK25_00600 306bfb28053cab2510edb79c15fe8642 102 ProSitePatterns PS00361 Ribosomal protein S10 signature. 29 44 - T 11-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00600 306bfb28053cab2510edb79c15fe8642 102 Gene3D G3DSA:3.30.70.600 1 102 2.6E-38 T 11-10-2018 IPR036838 Ribosomal protein S10 domain superfamily AFK25_00600 306bfb28053cab2510edb79c15fe8642 102 Pfam PF00338 Ribosomal protein S10p/S20e 7 101 6.2E-37 T 11-10-2018 IPR027486 Ribosomal protein S10 domain AFK25_00600 306bfb28053cab2510edb79c15fe8642 102 TIGRFAM TIGR01049 rpsJ_bact: ribosomal protein uS10 4 101 9.9E-47 T 11-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00600 306bfb28053cab2510edb79c15fe8642 102 SMART SM01403 7 101 1.0E-60 T 11-10-2018 IPR027486 Ribosomal protein S10 domain AFK25_00600 306bfb28053cab2510edb79c15fe8642 102 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 3 102 28.352 T 11-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00600 306bfb28053cab2510edb79c15fe8642 102 PRINTS PR00971 Ribosomal protein S10 family signature 40 55 5.6E-20 T 11-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00600 306bfb28053cab2510edb79c15fe8642 102 PRINTS PR00971 Ribosomal protein S10 family signature 5 18 5.6E-20 T 11-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00600 306bfb28053cab2510edb79c15fe8642 102 PRINTS PR00971 Ribosomal protein S10 family signature 61 75 5.6E-20 T 11-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_03480 db2446e90046da802e6ffba3699705bd 309 ProSitePatterns PS00211 ABC transporters family signature. 151 165 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_03480 db2446e90046da802e6ffba3699705bd 309 Gene3D G3DSA:3.40.50.300 1 308 6.0E-91 T 11-10-2018 AFK25_03480 db2446e90046da802e6ffba3699705bd 309 Pfam PF00005 ABC transporter 26 178 2.1E-33 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_03480 db2446e90046da802e6ffba3699705bd 309 SMART SM00382 34 228 1.6E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_03480 db2446e90046da802e6ffba3699705bd 309 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 278 6.7E-8 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFK25_03480 db2446e90046da802e6ffba3699705bd 309 SUPERFAMILY SSF52540 4 250 2.99E-75 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_07930 e3e7576c5b01c611d1342f4c7f4a8eb4 144 Gene3D G3DSA:3.30.300.180 1 74 1.5E-16 T 11-10-2018 IPR038454 DnaA, N-terminal domain superfamily AFK25_07930 e3e7576c5b01c611d1342f4c7f4a8eb4 144 Pfam PF11638 DnaA N-terminal domain 1 60 1.0E-8 T 11-10-2018 IPR024633 DnaA N-terminal domain AFK25_03455 09abac3a396ddf86d19a50c59917a49f 109 Pfam PF13038 Domain of unknown function (DUF3899) 30 107 3.4E-16 T 11-10-2018 IPR025007 Domain of unknown function DUF3899 AFK25_11460 4d520ebf2038db7777d22b6dfe53c14c 339 SUPERFAMILY SSF47413 3 51 1.69E-12 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFK25_11460 4d520ebf2038db7777d22b6dfe53c14c 339 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 3.1E-18 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_11460 4d520ebf2038db7777d22b6dfe53c14c 339 Gene3D G3DSA:3.40.50.2300 78 324 3.5E-56 T 11-10-2018 AFK25_11460 4d520ebf2038db7777d22b6dfe53c14c 339 SUPERFAMILY SSF53822 75 326 3.93E-51 T 11-10-2018 IPR028082 Periplasmic binding protein-like I AFK25_11460 4d520ebf2038db7777d22b6dfe53c14c 339 Gene3D G3DSA:1.10.260.40 1 47 1.9E-18 T 11-10-2018 AFK25_11460 4d520ebf2038db7777d22b6dfe53c14c 339 Pfam PF13377 Periplasmic binding protein-like domain 169 332 1.0E-38 T 11-10-2018 AFK25_11460 4d520ebf2038db7777d22b6dfe53c14c 339 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 11-10-2018 AFK25_11460 4d520ebf2038db7777d22b6dfe53c14c 339 Gene3D G3DSA:3.40.50.2300 160 326 3.5E-56 T 11-10-2018 AFK25_11460 4d520ebf2038db7777d22b6dfe53c14c 339 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 5.0E-6 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_11460 4d520ebf2038db7777d22b6dfe53c14c 339 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 5.0E-6 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_11460 4d520ebf2038db7777d22b6dfe53c14c 339 SMART SM00354 1 73 2.2E-14 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_01305 1b3ee4ebeb6124ec331b6d7e4c6df7e4 84 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 2 78 21.804 T 11-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFK25_01305 1b3ee4ebeb6124ec331b6d7e4c6df7e4 84 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 3 78 1.1E-31 T 11-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFK25_01305 1b3ee4ebeb6124ec331b6d7e4c6df7e4 84 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 10 80 1.0E-27 T 11-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFK25_01305 1b3ee4ebeb6124ec331b6d7e4c6df7e4 84 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 2 80 2.6E-33 T 11-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFK25_01305 1b3ee4ebeb6124ec331b6d7e4c6df7e4 84 SUPERFAMILY SSF82697 1 80 1.36E-29 T 11-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFK25_01305 1b3ee4ebeb6124ec331b6d7e4c6df7e4 84 Gene3D G3DSA:3.30.1280.10 1 84 5.1E-36 T 11-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFK25_00890 bcf742e8a6ed3966f84322775ca8defa 273 PIRSF PIRSF004793 5 270 7.4E-99 T 11-10-2018 IPR014046 Diadenylate cyclase GO:0004016|GO:0006171 AFK25_00890 bcf742e8a6ed3966f84322775ca8defa 273 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 119 236 2.2E-45 T 11-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal AFK25_00890 bcf742e8a6ed3966f84322775ca8defa 273 Gene3D G3DSA:3.40.1700.10 103 256 4.2E-65 T 11-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily AFK25_00890 bcf742e8a6ed3966f84322775ca8defa 273 TIGRFAM TIGR00159 TIGR00159: TIGR00159 family protein 6 257 1.4E-101 T 11-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 AFK25_00890 bcf742e8a6ed3966f84322775ca8defa 273 Hamap MF_01499 Diadenylate cyclase [dacA]. 9 255 34.985 T 11-10-2018 IPR034701 Diadenylate cyclase CdaA GO:0004016|GO:0006171 AFK25_00890 bcf742e8a6ed3966f84322775ca8defa 273 SUPERFAMILY SSF143597 41 241 6.41E-74 T 11-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily AFK25_11425 89470b3438a90ae94ff3b906167676eb 435 Gene3D G3DSA:3.40.190.10 59 392 3.3E-119 T 11-10-2018 AFK25_11425 89470b3438a90ae94ff3b906167676eb 435 Pfam PF01547 Bacterial extracellular solute-binding protein 57 348 1.5E-37 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFK25_11425 89470b3438a90ae94ff3b906167676eb 435 Gene3D G3DSA:3.40.190.10 156 423 3.3E-119 T 11-10-2018 AFK25_11425 89470b3438a90ae94ff3b906167676eb 435 SUPERFAMILY SSF53850 19 432 8.89E-83 T 11-10-2018 AFK25_08110 a11d3be253524fcf458facb842e902d8 658 Gene3D G3DSA:3.40.50.12780 76 520 3.4E-67 T 11-10-2018 AFK25_08110 a11d3be253524fcf458facb842e902d8 658 SUPERFAMILY SSF56801 27 643 3.27E-130 T 11-10-2018 AFK25_08110 a11d3be253524fcf458facb842e902d8 658 Gene3D G3DSA:3.30.300.30 523 636 1.9E-11 T 11-10-2018 AFK25_08110 a11d3be253524fcf458facb842e902d8 658 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 9 651 2.2E-257 T 11-10-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 AFK25_08110 a11d3be253524fcf458facb842e902d8 658 ProSitePatterns PS00455 Putative AMP-binding domain signature. 269 280 - T 11-10-2018 IPR020845 AMP-binding, conserved site AFK25_08110 a11d3be253524fcf458facb842e902d8 658 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 42 95 1.2E-10 T 11-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 AFK25_08110 a11d3be253524fcf458facb842e902d8 658 Pfam PF00501 AMP-binding enzyme 101 526 8.0E-54 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFK25_01340 2d012d1a6a7f353304e8419669af8bbe 426 SMART SM01210 325 416 1.9E-46 T 11-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFK25_01340 2d012d1a6a7f353304e8419669af8bbe 426 ProSitePatterns PS00184 Phosphoribosylglycinamide synthetase signature. 287 294 - T 11-10-2018 IPR020559 Phosphoribosylglycinamide synthetase, conserved site GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFK25_01340 2d012d1a6a7f353304e8419669af8bbe 426 SUPERFAMILY SSF51246 324 416 1.02E-29 T 11-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFK25_01340 2d012d1a6a7f353304e8419669af8bbe 426 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 101 293 5.9E-83 T 11-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFK25_01340 2d012d1a6a7f353304e8419669af8bbe 426 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 100 2.7E-35 T 11-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFK25_01340 2d012d1a6a7f353304e8419669af8bbe 426 Gene3D G3DSA:3.30.1490.20 119 188 2.1E-27 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFK25_01340 2d012d1a6a7f353304e8419669af8bbe 426 SUPERFAMILY SSF56059 102 322 3.01E-63 T 11-10-2018 AFK25_01340 2d012d1a6a7f353304e8419669af8bbe 426 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 416 1.3E-170 T 11-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFK25_01340 2d012d1a6a7f353304e8419669af8bbe 426 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 327 413 9.3E-29 T 11-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFK25_01340 2d012d1a6a7f353304e8419669af8bbe 426 Gene3D G3DSA:3.30.470.20 189 324 5.4E-57 T 11-10-2018 AFK25_01340 2d012d1a6a7f353304e8419669af8bbe 426 SUPERFAMILY SSF52440 1 101 8.78E-35 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFK25_01340 2d012d1a6a7f353304e8419669af8bbe 426 Gene3D G3DSA:3.40.50.20 2 93 2.5E-37 T 11-10-2018 AFK25_01340 2d012d1a6a7f353304e8419669af8bbe 426 SMART SM01209 101 293 3.2E-130 T 11-10-2018 AFK25_01340 2d012d1a6a7f353304e8419669af8bbe 426 Gene3D G3DSA:3.90.600.10 325 425 1.6E-33 T 11-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFK25_01340 2d012d1a6a7f353304e8419669af8bbe 426 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 416 42.473 T 11-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AFK25_10665 2b8f28219ad3ce750302d9d28b22229b 360 Pfam PF02618 YceG-like family 53 354 2.2E-84 T 11-10-2018 IPR003770 Endolytic murein transglycosylase AFK25_10665 2b8f28219ad3ce750302d9d28b22229b 360 Hamap MF_02065 Endolytic murein transglycosylase [mltG]. 13 360 34.548 T 11-10-2018 IPR003770 Endolytic murein transglycosylase AFK25_10665 2b8f28219ad3ce750302d9d28b22229b 360 Gene3D G3DSA:1.10.8.1150 47 122 2.1E-28 T 11-10-2018 AFK25_10665 2b8f28219ad3ce750302d9d28b22229b 360 TIGRFAM TIGR00247 TIGR00247: conserved hypothetical protein, YceG family 13 357 1.3E-107 T 11-10-2018 IPR003770 Endolytic murein transglycosylase AFK25_08130 fdb6ebeeee123417e30ac23c1ff35d3a 300 SMART SM00382 27 215 5.8E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_08130 fdb6ebeeee123417e30ac23c1ff35d3a 300 Pfam PF13732 Domain of unknown function (DUF4162) 212 294 1.2E-19 T 11-10-2018 IPR025302 Domain of unknown function DUF4162 AFK25_08130 fdb6ebeeee123417e30ac23c1ff35d3a 300 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_08130 fdb6ebeeee123417e30ac23c1ff35d3a 300 Gene3D G3DSA:3.40.50.300 1 229 1.7E-61 T 11-10-2018 AFK25_08130 fdb6ebeeee123417e30ac23c1ff35d3a 300 SUPERFAMILY SSF52540 3 223 1.74E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_08130 fdb6ebeeee123417e30ac23c1ff35d3a 300 Pfam PF00005 ABC transporter 19 158 1.4E-28 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_07850 577d68a620ff2a993e00a6075c9602e7 239 Pfam PF00929 Exonuclease 59 211 3.8E-18 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFK25_07850 577d68a620ff2a993e00a6075c9602e7 239 Gene3D G3DSA:3.30.420.10 49 223 2.6E-32 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFK25_07850 577d68a620ff2a993e00a6075c9602e7 239 SUPERFAMILY SSF53098 47 225 2.66E-36 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_07850 577d68a620ff2a993e00a6075c9602e7 239 SMART SM00479 56 222 1.2E-17 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFK25_07905 2b15ce3014229d6ee69e59517876831e 436 Pfam PF13439 Glycosyltransferase Family 4 21 169 7.8E-9 T 11-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AFK25_07905 2b15ce3014229d6ee69e59517876831e 436 SUPERFAMILY SSF53756 2 378 4.32E-73 T 11-10-2018 AFK25_07905 2b15ce3014229d6ee69e59517876831e 436 Gene3D G3DSA:3.40.50.2000 166 365 1.9E-66 T 11-10-2018 AFK25_07905 2b15ce3014229d6ee69e59517876831e 436 Pfam PF00534 Glycosyl transferases group 1 184 357 4.5E-39 T 11-10-2018 IPR001296 Glycosyl transferase, family 1 AFK25_07905 2b15ce3014229d6ee69e59517876831e 436 Gene3D G3DSA:3.40.50.2000 14 366 1.9E-66 T 11-10-2018 AFK25_11445 7d14235c26f4af36ec90f9c3c44935dd 327 Pfam PF00248 Aldo/keto reductase family 16 314 1.2E-61 T 11-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFK25_11445 7d14235c26f4af36ec90f9c3c44935dd 327 Gene3D G3DSA:3.20.20.100 1 323 2.1E-87 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFK25_11445 7d14235c26f4af36ec90f9c3c44935dd 327 PRINTS PR00069 Aldo-keto reductase signature 137 154 1.8E-6 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFK25_11445 7d14235c26f4af36ec90f9c3c44935dd 327 PRINTS PR00069 Aldo-keto reductase signature 42 66 1.8E-6 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFK25_11445 7d14235c26f4af36ec90f9c3c44935dd 327 PRINTS PR00069 Aldo-keto reductase signature 105 123 1.8E-6 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFK25_11445 7d14235c26f4af36ec90f9c3c44935dd 327 SUPERFAMILY SSF51430 1 320 7.99E-83 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFK25_03590 d0d8c2ad3faab49c1047194b287983b2 118 Pfam PF14153 Spore coat protein CotO 39 116 2.0E-14 T 11-10-2018 IPR025439 Spore coat protein CotO AFK25_05505 16630047393e65d6a56aa991c0050914 329 SUPERFAMILY SSF53659 1 327 3.08E-105 T 11-10-2018 AFK25_05505 16630047393e65d6a56aa991c0050914 329 TIGRFAM TIGR00182 plsX: fatty acid/phospholipid synthesis protein PlsX 1 327 9.5E-134 T 11-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 AFK25_05505 16630047393e65d6a56aa991c0050914 329 Hamap MF_00019 Phosphate acyltransferase [plsX]. 1 329 153.136 T 11-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 AFK25_05505 16630047393e65d6a56aa991c0050914 329 Gene3D G3DSA:3.40.718.10 1 329 3.3E-138 T 11-10-2018 AFK25_05505 16630047393e65d6a56aa991c0050914 329 PIRSF PIRSF002465 1 329 2.1E-129 T 11-10-2018 IPR012281 Phospholipid biosynthesis protein, PlsX-like GO:0006633 AFK25_05505 16630047393e65d6a56aa991c0050914 329 Pfam PF02504 Fatty acid synthesis protein 1 318 9.3E-125 T 11-10-2018 IPR003664 Fatty acid synthesis PlsX protein GO:0003824|GO:0006633|GO:0016747 AFK25_07650 124c16cb046eaca9a39d7d8eb9bdf2a5 139 Pfam PF03061 Thioesterase superfamily 18 99 4.6E-14 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFK25_07650 124c16cb046eaca9a39d7d8eb9bdf2a5 139 Gene3D G3DSA:3.10.129.10 2 128 5.6E-37 T 11-10-2018 AFK25_07650 124c16cb046eaca9a39d7d8eb9bdf2a5 139 TIGRFAM TIGR00051 TIGR00051: acyl-CoA thioester hydrolase, YbgC/YbaW family 9 122 6.1E-35 T 11-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 AFK25_07650 124c16cb046eaca9a39d7d8eb9bdf2a5 139 PIRSF PIRSF003230 1 136 3.1E-32 T 11-10-2018 IPR006684 Acyl-CoA thioester hydrolase YbgC/YbaW family GO:0016787 AFK25_07650 124c16cb046eaca9a39d7d8eb9bdf2a5 139 SUPERFAMILY SSF54637 2 133 6.2E-41 T 11-10-2018 IPR029069 HotDog domain superfamily AFK25_13510 d87a72484fbf2e3b6d6f0c797f36ee5a 1146 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 159 170 - T 11-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site AFK25_13510 d87a72484fbf2e3b6d6f0c797f36ee5a 1146 SUPERFAMILY SSF52743 140 411 2.75E-90 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFK25_13510 d87a72484fbf2e3b6d6f0c797f36ee5a 1146 Gene3D G3DSA:2.60.120.380 568 674 5.5E-5 T 11-10-2018 AFK25_13510 d87a72484fbf2e3b6d6f0c797f36ee5a 1146 Pfam PF00082 Subtilase family 155 401 2.4E-53 T 11-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AFK25_13510 d87a72484fbf2e3b6d6f0c797f36ee5a 1146 SUPERFAMILY SSF89260 1054 1128 1.15E-6 T 11-10-2018 AFK25_13510 d87a72484fbf2e3b6d6f0c797f36ee5a 1146 Gene3D G3DSA:2.60.120.380 1027 1146 4.8E-14 T 11-10-2018 AFK25_13510 d87a72484fbf2e3b6d6f0c797f36ee5a 1146 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 195 205 - T 11-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site AFK25_13510 d87a72484fbf2e3b6d6f0c797f36ee5a 1146 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 351 361 - T 11-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AFK25_13510 d87a72484fbf2e3b6d6f0c797f36ee5a 1146 Pfam PF04151 Bacterial pre-peptidase C-terminal domain 1062 1128 1.3E-5 T 11-10-2018 IPR007280 Peptidase, C-terminal, archaeal/bacterial AFK25_13510 d87a72484fbf2e3b6d6f0c797f36ee5a 1146 PRINTS PR00723 Subtilisin serine protease family (S8) signature 154 173 8.7E-16 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related AFK25_13510 d87a72484fbf2e3b6d6f0c797f36ee5a 1146 PRINTS PR00723 Subtilisin serine protease family (S8) signature 350 366 8.7E-16 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related AFK25_13510 d87a72484fbf2e3b6d6f0c797f36ee5a 1146 PRINTS PR00723 Subtilisin serine protease family (S8) signature 191 204 8.7E-16 T 11-10-2018 IPR015500 Peptidase S8, subtilisin-related AFK25_13510 d87a72484fbf2e3b6d6f0c797f36ee5a 1146 Gene3D G3DSA:3.40.50.200 99 418 1.3E-94 T 11-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AFK25_13510 d87a72484fbf2e3b6d6f0c797f36ee5a 1146 Gene3D G3DSA:2.60.120.380 760 872 6.3E-9 T 11-10-2018 AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 SUPERFAMILY SSF51905 197 505 8.43E-54 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 337 357 - T 11-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 Gene3D G3DSA:3.50.50.60 319 441 4.1E-111 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 209 488 6.7E-49 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 SUPERFAMILY SSF52833 103 194 1.56E-23 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 Gene3D G3DSA:3.50.50.60 209 499 4.1E-111 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 Pfam PF13192 Thioredoxin domain 124 193 2.9E-9 T 11-10-2018 IPR012336 Thioredoxin-like fold AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 Gene3D G3DSA:3.40.30.80 2 199 8.0E-62 T 11-10-2018 AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 242 257 1.8E-69 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 397 413 1.8E-69 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 210 232 1.8E-69 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 330 342 1.8E-69 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 308 316 1.8E-69 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 345 369 1.8E-69 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 469 487 1.8E-69 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 262 272 1.8E-69 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 435 456 1.8E-69 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 TIGRFAM TIGR03140 AhpF: alkyl hydroperoxide reductase subunit F 2 509 2.5E-245 T 11-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 PIRSF PIRSF000238 2 509 9.9E-261 T 11-10-2018 IPR012081 Alkyl hydroperoxide reductase subunit F GO:0000302|GO:0008785|GO:0050660|GO:0051287 AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 SUPERFAMILY SSF52833 2 101 1.45E-28 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 459 481 1.6E-41 T 11-10-2018 AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 307 325 1.6E-41 T 11-10-2018 AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 211 230 1.6E-41 T 11-10-2018 AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 433 449 1.6E-41 T 11-10-2018 AFK25_14175 636886cafa795b6b88d7fcf7cad3552f 509 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 349 367 1.6E-41 T 11-10-2018 AFK25_02690 8c8183456391cb5901a146f266bc548a 482 Gene3D G3DSA:3.40.50.300 2 272 1.1E-59 T 11-10-2018 AFK25_02690 8c8183456391cb5901a146f266bc548a 482 Pfam PF00005 ABC transporter 280 416 1.0E-22 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_02690 8c8183456391cb5901a146f266bc548a 482 SUPERFAMILY SSF52540 4 224 1.3E-49 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_02690 8c8183456391cb5901a146f266bc548a 482 Gene3D G3DSA:3.40.50.300 273 477 5.5E-48 T 11-10-2018 AFK25_02690 8c8183456391cb5901a146f266bc548a 482 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_02690 8c8183456391cb5901a146f266bc548a 482 Pfam PF00005 ABC transporter 23 162 1.1E-25 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_02690 8c8183456391cb5901a146f266bc548a 482 SUPERFAMILY SSF52540 278 471 9.06E-42 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_02690 8c8183456391cb5901a146f266bc548a 482 SMART SM00382 283 465 2.3E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_02690 8c8183456391cb5901a146f266bc548a 482 SMART SM00382 31 209 2.6E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_12230 8fdabb53e4234174a8f2f3f611e9d402 651 Pfam PF02239 Cytochrome D1 heme domain 97 210 2.0E-11 T 11-10-2018 AFK25_12230 8fdabb53e4234174a8f2f3f611e9d402 651 Gene3D G3DSA:1.10.760.10 380 505 7.9E-8 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFK25_12230 8fdabb53e4234174a8f2f3f611e9d402 651 Gene3D G3DSA:2.130.10.10 23 269 3.5E-50 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFK25_12230 8fdabb53e4234174a8f2f3f611e9d402 651 Gene3D G3DSA:1.10.760.10 506 651 5.7E-25 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFK25_12230 8fdabb53e4234174a8f2f3f611e9d402 651 Pfam PF10282 Lactonase, 7-bladed beta-propeller 290 364 3.3E-6 T 11-10-2018 IPR019405 Lactonase, 7-bladed beta propeller AFK25_12230 8fdabb53e4234174a8f2f3f611e9d402 651 Gene3D G3DSA:2.130.10.10 270 377 1.6E-9 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFK25_12230 8fdabb53e4234174a8f2f3f611e9d402 651 SUPERFAMILY SSF46626 516 650 9.43E-24 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFK25_12230 8fdabb53e4234174a8f2f3f611e9d402 651 SUPERFAMILY SSF51004 44 367 1.44E-52 T 11-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily AFK25_12230 8fdabb53e4234174a8f2f3f611e9d402 651 SUPERFAMILY SSF46626 382 496 2.69E-11 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFK25_12230 8fdabb53e4234174a8f2f3f611e9d402 651 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 128 168 3.6E-8 T 11-10-2018 IPR011964 YVTN beta-propeller repeat AFK25_12230 8fdabb53e4234174a8f2f3f611e9d402 651 TIGRFAM TIGR02276 beta_rpt_yvtn: 40-residue YVTN family beta-propeller repeat 45 83 1.9E-7 T 11-10-2018 IPR011964 YVTN beta-propeller repeat AFK25_12230 8fdabb53e4234174a8f2f3f611e9d402 651 Pfam PF06537 Di-haem oxidoreductase, putative peroxidase 523 650 1.0E-8 T 11-10-2018 IPR010538 Di-haem oxidoreductase, putative peroxidase AFK25_07780 c20e3128d4a07751e0aecbbb60fa2d26 263 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 9 255 34.067 T 11-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFK25_07780 c20e3128d4a07751e0aecbbb60fa2d26 263 PIRSF PIRSF000513 1 262 8.8E-98 T 11-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFK25_07780 c20e3128d4a07751e0aecbbb60fa2d26 263 Pfam PF02110 Hydroxyethylthiazole kinase family 7 251 1.2E-91 T 11-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFK25_07780 c20e3128d4a07751e0aecbbb60fa2d26 263 Gene3D G3DSA:3.40.1190.20 1 262 2.7E-98 T 11-10-2018 IPR029056 Ribokinase-like AFK25_07780 c20e3128d4a07751e0aecbbb60fa2d26 263 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 7 253 1.2E-94 T 11-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFK25_07780 c20e3128d4a07751e0aecbbb60fa2d26 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 116 130 3.3E-42 T 11-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFK25_07780 c20e3128d4a07751e0aecbbb60fa2d26 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 85 102 3.3E-42 T 11-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFK25_07780 c20e3128d4a07751e0aecbbb60fa2d26 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 59 67 3.3E-42 T 11-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFK25_07780 c20e3128d4a07751e0aecbbb60fa2d26 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 15 22 3.3E-42 T 11-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFK25_07780 c20e3128d4a07751e0aecbbb60fa2d26 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 160 177 3.3E-42 T 11-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFK25_07780 c20e3128d4a07751e0aecbbb60fa2d26 263 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 28 49 3.3E-42 T 11-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFK25_07780 c20e3128d4a07751e0aecbbb60fa2d26 263 SUPERFAMILY SSF53613 6 259 2.65E-65 T 11-10-2018 IPR029056 Ribokinase-like AFK25_09620 a4509d76469f51c03b3826cd8035e944 140 SUPERFAMILY SSF82093 40 128 5.62E-23 T 11-10-2018 IPR036127 CcmE-like superfamily GO:0005886|GO:0017003|GO:0017004 AFK25_09620 a4509d76469f51c03b3826cd8035e944 140 Pfam PF03100 CcmE 5 123 1.3E-27 T 11-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 AFK25_09620 a4509d76469f51c03b3826cd8035e944 140 Gene3D G3DSA:2.40.50.140 21 130 3.5E-22 T 11-10-2018 AFK25_12310 3816ff06869e3a5ae0874964e9515960 390 TIGRFAM TIGR02092 glgD: glucose-1-phosphate adenylyltransferase, GlgD subunit 5 365 1.2E-71 T 11-10-2018 IPR011832 Glucose-1-phosphate adenylyltransferase, GlgD subunit GO:0005978 AFK25_12310 3816ff06869e3a5ae0874964e9515960 390 ProSitePatterns PS00808 ADP-glucose pyrophosphorylase signature 1. 12 31 - T 11-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 AFK25_12310 3816ff06869e3a5ae0874964e9515960 390 SUPERFAMILY SSF53448 2 340 2.46E-88 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_12310 3816ff06869e3a5ae0874964e9515960 390 TIGRFAM TIGR02091 glgC: glucose-1-phosphate adenylyltransferase 6 359 4.8E-151 T 11-10-2018 IPR011831 Glucose-1-phosphate adenylyltransferase GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 AFK25_12310 3816ff06869e3a5ae0874964e9515960 390 ProSitePatterns PS00810 ADP-glucose pyrophosphorylase signature 3. 190 200 - T 11-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 AFK25_12310 3816ff06869e3a5ae0874964e9515960 390 ProSitePatterns PS00809 ADP-glucose pyrophosphorylase signature 2. 99 107 - T 11-10-2018 IPR005836 ADP-glucose pyrophosphorylase, conserved site GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 AFK25_12310 3816ff06869e3a5ae0874964e9515960 390 Gene3D G3DSA:2.160.10.10 275 385 3.8E-28 T 11-10-2018 AFK25_12310 3816ff06869e3a5ae0874964e9515960 390 Hamap MF_00624 Glucose-1-phosphate adenylyltransferase [glgC]. 3 376 49.828 T 11-10-2018 IPR023049 Glucose-1-phosphate adenylyltransferase GlgC, bacterial GO:0005978|GO:0008878 KEGG: 00500+2.7.7.27|KEGG: 00520+2.7.7.27|MetaCyc: PWY-622|MetaCyc: PWY-7902 AFK25_12310 3816ff06869e3a5ae0874964e9515960 390 Gene3D G3DSA:3.90.550.10 2 274 1.7E-96 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_12310 3816ff06869e3a5ae0874964e9515960 390 SUPERFAMILY SSF51161 287 364 7.07E-15 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily AFK25_12310 3816ff06869e3a5ae0874964e9515960 390 Pfam PF00483 Nucleotidyl transferase 8 260 1.1E-73 T 11-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFK25_00660 162ebb9b0fa122022a5c33d225aea2b6 103 ProSitePatterns PS01108 Ribosomal protein L24 signature. 6 23 - T 11-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00660 162ebb9b0fa122022a5c33d225aea2b6 103 Gene3D G3DSA:2.30.30.30 1 100 1.2E-44 T 11-10-2018 IPR014722 Ribosomal protein L2, domain 2 AFK25_00660 162ebb9b0fa122022a5c33d225aea2b6 103 SMART SM00739 2 29 3.1E-6 T 11-10-2018 IPR005824 KOW AFK25_00660 162ebb9b0fa122022a5c33d225aea2b6 103 Pfam PF00467 KOW motif 5 36 1.0E-9 T 11-10-2018 IPR005824 KOW AFK25_00660 162ebb9b0fa122022a5c33d225aea2b6 103 Pfam PF17136 Ribosomal proteins 50S L24/mitochondrial 39S L24 38 100 4.4E-32 T 11-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00660 162ebb9b0fa122022a5c33d225aea2b6 103 SUPERFAMILY SSF50104 1 100 1.88E-40 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily AFK25_00660 162ebb9b0fa122022a5c33d225aea2b6 103 TIGRFAM TIGR01079 rplX_bact: ribosomal protein uL24 1 101 1.7E-42 T 11-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00660 162ebb9b0fa122022a5c33d225aea2b6 103 Hamap MF_01326_B 50S ribosomal protein L24 [rplX]. 1 95 23.526 T 11-10-2018 IPR003256 Ribosomal protein L24 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10305 d5d561663a5d88b5165b821a47a970ab 302 TIGRFAM TIGR00436 era: GTP-binding protein Era 9 280 4.6E-112 T 11-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10305 d5d561663a5d88b5165b821a47a970ab 302 Pfam PF01926 50S ribosome-binding GTPase 11 125 7.3E-26 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_10305 d5d561663a5d88b5165b821a47a970ab 302 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 11 31 5.0E-5 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_10305 d5d561663a5d88b5165b821a47a970ab 302 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 102 5.0E-5 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_10305 d5d561663a5d88b5165b821a47a970ab 302 Pfam PF07650 KH domain 208 286 2.9E-22 T 11-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_10305 d5d561663a5d88b5165b821a47a970ab 302 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 168 9.5E-31 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFK25_10305 d5d561663a5d88b5165b821a47a970ab 302 Hamap MF_00367 GTPase Era [era]. 6 297 39.917 T 11-10-2018 IPR005662 GTP-binding protein Era GO:0003723|GO:0005525|GO:0005622 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10305 d5d561663a5d88b5165b821a47a970ab 302 Gene3D G3DSA:3.40.50.300 4 185 3.8E-51 T 11-10-2018 AFK25_10305 d5d561663a5d88b5165b821a47a970ab 302 SUPERFAMILY SSF54814 183 298 3.6E-43 T 11-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AFK25_10305 d5d561663a5d88b5165b821a47a970ab 302 SUPERFAMILY SSF52540 11 206 9.59E-53 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_10305 d5d561663a5d88b5165b821a47a970ab 302 Gene3D G3DSA:3.30.300.20 186 299 1.2E-45 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta AFK25_06735 73c2f1b9329d6f983bd6700e68e72e2e 518 TIGRFAM TIGR00277 HDIG: HDIG domain 330 407 1.0E-25 T 11-10-2018 IPR006675 HDIG domain AFK25_06735 73c2f1b9329d6f983bd6700e68e72e2e 518 SMART SM00322 206 273 1.1E-6 T 11-10-2018 IPR004087 K Homology domain GO:0003676 AFK25_06735 73c2f1b9329d6f983bd6700e68e72e2e 518 Pfam PF00013 KH domain 211 265 3.4E-6 T 11-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 AFK25_06735 73c2f1b9329d6f983bd6700e68e72e2e 518 Gene3D G3DSA:1.10.3210.10 317 470 2.0E-19 T 11-10-2018 AFK25_06735 73c2f1b9329d6f983bd6700e68e72e2e 518 Pfam PF12072 Domain of unknown function (DUF3552) 4 203 9.5E-77 T 11-10-2018 IPR022711 Ribonuclease Y, N-terminal AFK25_06735 73c2f1b9329d6f983bd6700e68e72e2e 518 Pfam PF01966 HD domain 335 426 2.8E-19 T 11-10-2018 IPR006674 HD domain AFK25_06735 73c2f1b9329d6f983bd6700e68e72e2e 518 TIGRFAM TIGR03319 RNase_Y: ribonuclease Y 6 518 1.8E-249 T 11-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 AFK25_06735 73c2f1b9329d6f983bd6700e68e72e2e 518 SUPERFAMILY SSF109604 314 465 3.37E-31 T 11-10-2018 AFK25_06735 73c2f1b9329d6f983bd6700e68e72e2e 518 Gene3D G3DSA:3.30.1370.10 206 308 1.1E-8 T 11-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AFK25_06735 73c2f1b9329d6f983bd6700e68e72e2e 518 SUPERFAMILY SSF54791 206 302 3.04E-16 T 11-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AFK25_06735 73c2f1b9329d6f983bd6700e68e72e2e 518 Hamap MF_00335 Ribonuclease Y [rny]. 3 518 26.268 T 11-10-2018 IPR017705 Ribonuclease Y GO:0003723|GO:0006402|GO:0016020 AFK25_06735 73c2f1b9329d6f983bd6700e68e72e2e 518 SMART SM00471 330 436 4.2E-14 T 11-10-2018 IPR003607 HD/PDEase domain AFK25_01315 744c6589872ff6aba1daf2a6544bb189 740 Pfam PF00586 AIR synthase related protein, N-terminal domain 92 194 2.7E-24 T 11-10-2018 IPR016188 PurM-like, N-terminal domain AFK25_01315 744c6589872ff6aba1daf2a6544bb189 740 Pfam PF00586 AIR synthase related protein, N-terminal domain 444 561 2.9E-25 T 11-10-2018 IPR016188 PurM-like, N-terminal domain AFK25_01315 744c6589872ff6aba1daf2a6544bb189 740 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 740 331.169 T 11-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFK25_01315 744c6589872ff6aba1daf2a6544bb189 740 SUPERFAMILY SSF56042 205 429 1.12E-58 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFK25_01315 744c6589872ff6aba1daf2a6544bb189 740 SUPERFAMILY SSF55326 18 201 1.94E-51 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFK25_01315 744c6589872ff6aba1daf2a6544bb189 740 SUPERFAMILY SSF56042 571 736 4.49E-39 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFK25_01315 744c6589872ff6aba1daf2a6544bb189 740 Gene3D G3DSA:3.90.650.10 34 362 1.1E-136 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFK25_01315 744c6589872ff6aba1daf2a6544bb189 740 Gene3D G3DSA:3.30.1330.10 49 197 1.1E-136 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFK25_01315 744c6589872ff6aba1daf2a6544bb189 740 SUPERFAMILY SSF55326 401 569 3.27E-60 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFK25_01315 744c6589872ff6aba1daf2a6544bb189 740 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 23 735 0.0 T 11-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFK25_01315 744c6589872ff6aba1daf2a6544bb189 740 PIRSF PIRSF001587 8 739 0.0 T 11-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFK25_01315 744c6589872ff6aba1daf2a6544bb189 740 Gene3D G3DSA:3.30.1330.10 387 564 8.9E-65 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFK25_01315 744c6589872ff6aba1daf2a6544bb189 740 Gene3D G3DSA:3.90.650.10 569 738 7.9E-39 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFK25_01315 744c6589872ff6aba1daf2a6544bb189 740 Pfam PF02769 AIR synthase related protein, C-terminal domain 574 707 3.1E-13 T 11-10-2018 IPR010918 PurM-like, C-terminal domain AFK25_01315 744c6589872ff6aba1daf2a6544bb189 740 Pfam PF02769 AIR synthase related protein, C-terminal domain 207 359 7.8E-36 T 11-10-2018 IPR010918 PurM-like, C-terminal domain AFK25_00900 a6c0f954a70216ccbb8ec877d3a4d9d7 447 Gene3D G3DSA:3.40.120.10 256 339 6.2E-75 T 11-10-2018 AFK25_00900 a6c0f954a70216ccbb8ec877d3a4d9d7 447 Gene3D G3DSA:3.40.120.10 174 362 6.2E-75 T 11-10-2018 AFK25_00900 a6c0f954a70216ccbb8ec877d3a4d9d7 447 SUPERFAMILY SSF55957 357 446 3.4E-27 T 11-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_00900 a6c0f954a70216ccbb8ec877d3a4d9d7 447 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 94 103 - T 11-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_00900 a6c0f954a70216ccbb8ec877d3a4d9d7 447 Hamap MF_01554_B Phosphoglucosamine mutase [glmM]. 1 444 45.801 T 11-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_00900 a6c0f954a70216ccbb8ec877d3a4d9d7 447 SUPERFAMILY SSF53738 158 256 1.45E-26 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_00900 a6c0f954a70216ccbb8ec877d3a4d9d7 447 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 158 253 1.1E-16 T 11-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_00900 a6c0f954a70216ccbb8ec877d3a4d9d7 447 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 3 135 2.2E-42 T 11-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_00900 a6c0f954a70216ccbb8ec877d3a4d9d7 447 Gene3D G3DSA:3.40.120.10 3 155 1.2E-58 T 11-10-2018 AFK25_00900 a6c0f954a70216ccbb8ec877d3a4d9d7 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 233 248 1.1E-11 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_00900 a6c0f954a70216ccbb8ec877d3a4d9d7 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 173 192 1.1E-11 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_00900 a6c0f954a70216ccbb8ec877d3a4d9d7 447 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 1.1E-11 T 11-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_00900 a6c0f954a70216ccbb8ec877d3a4d9d7 447 Gene3D G3DSA:3.30.310.50 370 447 3.6E-29 T 11-10-2018 AFK25_00900 a6c0f954a70216ccbb8ec877d3a4d9d7 447 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 442 1.3E-16 T 11-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_00900 a6c0f954a70216ccbb8ec877d3a4d9d7 447 SUPERFAMILY SSF53738 3 180 3.65E-46 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_00900 a6c0f954a70216ccbb8ec877d3a4d9d7 447 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 369 7.6E-39 T 11-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_00900 a6c0f954a70216ccbb8ec877d3a4d9d7 447 TIGRFAM TIGR01455 glmM: phosphoglucosamine mutase 5 442 6.9E-190 T 11-10-2018 IPR006352 Phosphoglucosamine mutase, bacterial type GO:0000287|GO:0005975|GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_00900 a6c0f954a70216ccbb8ec877d3a4d9d7 447 SUPERFAMILY SSF53738 257 365 6.67E-36 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_04675 16967046d70169ca0d9a2bc025cec58b 288 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 3 161 6.7E-55 T 11-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 AFK25_04675 16967046d70169ca0d9a2bc025cec58b 288 PIRSF PIRSF000103 1 288 9.2E-80 T 11-10-2018 IPR015815 3-hydroxyisobutyrate dehydrogenase-related GO:0016491|GO:0055114 Reactome: R-HSA-70895 AFK25_04675 16967046d70169ca0d9a2bc025cec58b 288 Gene3D G3DSA:3.40.50.720 1 163 5.9E-58 T 11-10-2018 AFK25_04675 16967046d70169ca0d9a2bc025cec58b 288 SUPERFAMILY SSF48179 163 287 5.1E-41 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFK25_04675 16967046d70169ca0d9a2bc025cec58b 288 Gene3D G3DSA:1.10.1040.10 164 288 2.6E-42 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFK25_04675 16967046d70169ca0d9a2bc025cec58b 288 SUPERFAMILY SSF51735 3 163 8.98E-53 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_04675 16967046d70169ca0d9a2bc025cec58b 288 Pfam PF14833 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase 165 285 5.2E-38 T 11-10-2018 IPR029154 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain GO:0051287 AFK25_04675 16967046d70169ca0d9a2bc025cec58b 288 ProSitePatterns PS00895 3-hydroxyisobutyrate dehydrogenase signature. 6 19 - T 11-10-2018 IPR002204 3-hydroxyisobutyrate dehydrogenase-related, conserved site GO:0016491|GO:0055114 Reactome: R-HSA-70895 AFK25_00670 0957e14acbe94b6ddf35e972bf5259c7 61 ProSitePatterns PS00527 Ribosomal protein S14 signature. 23 45 - T 11-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00670 0957e14acbe94b6ddf35e972bf5259c7 61 Hamap MF_01364_B 30S ribosomal protein S14 type Z [rpsZ]. 1 61 26.064 T 11-10-2018 IPR023053 Ribosomal protein S14, type Z AFK25_00670 0957e14acbe94b6ddf35e972bf5259c7 61 Gene3D G3DSA:4.10.830.10 1 61 3.8E-31 T 11-10-2018 AFK25_00670 0957e14acbe94b6ddf35e972bf5259c7 61 SUPERFAMILY SSF57716 3 61 3.85E-22 T 11-10-2018 AFK25_00670 0957e14acbe94b6ddf35e972bf5259c7 61 Pfam PF00253 Ribosomal protein S14p/S29e 9 60 3.3E-25 T 11-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_01415 fec1ed085b6a4bd077b873d2c63e1c03 476 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 2 474 40.05 T 11-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 AFK25_01415 fec1ed085b6a4bd077b873d2c63e1c03 476 Gene3D G3DSA:1.10.10.410 413 476 1.3E-26 T 11-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal AFK25_01415 fec1ed085b6a4bd077b873d2c63e1c03 476 Pfam PF02934 GatB/GatE catalytic domain 5 286 2.1E-115 T 11-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 AFK25_01415 fec1ed085b6a4bd077b873d2c63e1c03 476 Gene3D G3DSA:1.10.150.380 298 411 1.0E-39 T 11-10-2018 AFK25_01415 fec1ed085b6a4bd077b873d2c63e1c03 476 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 142 156 - T 11-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 AFK25_01415 fec1ed085b6a4bd077b873d2c63e1c03 476 SMART SM00845 326 473 9.8E-82 T 11-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 AFK25_01415 fec1ed085b6a4bd077b873d2c63e1c03 476 SUPERFAMILY SSF89095 295 401 2.53E-37 T 11-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 AFK25_01415 fec1ed085b6a4bd077b873d2c63e1c03 476 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 1 473 2.6E-188 T 11-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 AFK25_01415 fec1ed085b6a4bd077b873d2c63e1c03 476 Pfam PF02637 GatB domain 326 473 3.3E-58 T 11-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 AFK25_01415 fec1ed085b6a4bd077b873d2c63e1c03 476 SUPERFAMILY SSF55931 4 294 2.55E-125 T 11-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFK25_01725 fb794b9c2be7616990fa0e192db7dc67 257 SUPERFAMILY SSF53790 1 246 1.2E-82 T 11-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFK25_01725 fb794b9c2be7616990fa0e192db7dc67 257 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 213 1.8E-48 T 11-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFK25_01725 fb794b9c2be7616990fa0e192db7dc67 257 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 2 238 1.4E-101 T 11-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFK25_01725 fb794b9c2be7616990fa0e192db7dc67 257 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 82 115 - T 11-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFK25_01725 fb794b9c2be7616990fa0e192db7dc67 257 Gene3D G3DSA:3.40.1010.10 1 117 5.2E-45 T 11-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFK25_01725 fb794b9c2be7616990fa0e192db7dc67 257 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 7 21 - T 11-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFK25_01725 fb794b9c2be7616990fa0e192db7dc67 257 Gene3D G3DSA:3.30.950.10 118 256 1.2E-52 T 11-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFK25_12995 0675cf9b491da2435493e4d2f7cd24ed 210 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 204 36.342 T 11-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AFK25_12995 0675cf9b491da2435493e4d2f7cd24ed 210 PIRSF PIRSF000495 1 207 1.3E-73 T 11-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AFK25_12995 0675cf9b491da2435493e4d2f7cd24ed 210 SUPERFAMILY SSF52317 2 204 2.92E-57 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_12995 0675cf9b491da2435493e4d2f7cd24ed 210 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 203 1.9E-69 T 11-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AFK25_12995 0675cf9b491da2435493e4d2f7cd24ed 210 Pfam PF00117 Glutamine amidotransferase class-I 4 198 1.7E-24 T 11-10-2018 IPR017926 Glutamine amidotransferase AFK25_12995 0675cf9b491da2435493e4d2f7cd24ed 210 Gene3D G3DSA:3.40.50.880 1 209 9.9E-74 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_04655 d52cccf86a292ea1b41068280ff6a4e6 87 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 38 53 - T 11-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site AFK25_04655 d52cccf86a292ea1b41068280ff6a4e6 87 ProSitePatterns PS00369 PTS HPR domain histidine phosphorylation site signature. 12 19 - T 11-10-2018 IPR001020 Phosphotransferase system, HPr histidine phosphorylation site AFK25_04655 d52cccf86a292ea1b41068280ff6a4e6 87 SUPERFAMILY SSF55594 2 82 2.75E-29 T 11-10-2018 IPR035895 HPr-like superfamily AFK25_04655 d52cccf86a292ea1b41068280ff6a4e6 87 PRINTS PR00107 Phosphocarrier protein signature 12 28 4.9E-27 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like AFK25_04655 d52cccf86a292ea1b41068280ff6a4e6 87 PRINTS PR00107 Phosphocarrier protein signature 52 69 4.9E-27 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like AFK25_04655 d52cccf86a292ea1b41068280ff6a4e6 87 PRINTS PR00107 Phosphocarrier protein signature 37 52 4.9E-27 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like AFK25_04655 d52cccf86a292ea1b41068280ff6a4e6 87 Pfam PF00381 PTS HPr component phosphorylation site 2 81 1.0E-31 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like AFK25_04655 d52cccf86a292ea1b41068280ff6a4e6 87 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 2 80 8.4E-34 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like AFK25_04655 d52cccf86a292ea1b41068280ff6a4e6 87 Gene3D G3DSA:3.30.1340.10 1 87 2.6E-37 T 11-10-2018 IPR035895 HPr-like superfamily AFK25_06825 18849333dadaf0619cd83ce6c8c3ec95 535 Gene3D G3DSA:3.30.300.310 429 533 2.2E-34 T 11-10-2018 AFK25_06825 18849333dadaf0619cd83ce6c8c3ec95 535 Pfam PF00501 AMP-binding enzyme 19 433 1.4E-92 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFK25_06825 18849333dadaf0619cd83ce6c8c3ec95 535 SUPERFAMILY SSF56801 5 530 7.46E-139 T 11-10-2018 AFK25_06825 18849333dadaf0619cd83ce6c8c3ec95 535 Gene3D G3DSA:3.40.50.12780 1 428 1.3E-125 T 11-10-2018 AFK25_06825 18849333dadaf0619cd83ce6c8c3ec95 535 Pfam PF13193 AMP-binding enzyme C-terminal domain 443 517 6.3E-19 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFK25_00745 e6507e9773fa88f903ad56c742f5e8bf 120 Gene3D G3DSA:3.90.1030.10 1 120 1.1E-51 T 11-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00745 e6507e9773fa88f903ad56c742f5e8bf 120 TIGRFAM TIGR00059 L17: ribosomal protein bL17 2 120 1.8E-48 T 11-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00745 e6507e9773fa88f903ad56c742f5e8bf 120 SUPERFAMILY SSF64263 2 120 7.72E-46 T 11-10-2018 IPR036373 Ribosomal protein L17 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00745 e6507e9773fa88f903ad56c742f5e8bf 120 ProSitePatterns PS01167 Ribosomal protein L17 signature. 30 52 - T 11-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00745 e6507e9773fa88f903ad56c742f5e8bf 120 Pfam PF01196 Ribosomal protein L17 16 120 1.6E-40 T 11-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00745 e6507e9773fa88f903ad56c742f5e8bf 120 Hamap MF_01368 50S ribosomal protein L17 [rplQ]. 1 120 29.356 T 11-10-2018 IPR000456 Ribosomal protein L17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_03430 3aff59ff7740f700ddf2a5a33fd3070c 413 SMART SM00825 Beta-ketoacyl synthase 6 413 5.6E-18 T 11-10-2018 IPR020841 Polyketide synthase, beta-ketoacyl synthase domain AFK25_03430 3aff59ff7740f700ddf2a5a33fd3070c 413 Pfam PF00109 Beta-ketoacyl synthase, N-terminal domain 4 246 4.6E-63 T 11-10-2018 IPR014030 Beta-ketoacyl synthase, N-terminal AFK25_03430 3aff59ff7740f700ddf2a5a33fd3070c 413 Gene3D G3DSA:3.40.47.10 1 254 1.2E-106 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_03430 3aff59ff7740f700ddf2a5a33fd3070c 413 ProSitePatterns PS00606 Beta-ketoacyl synthases active site. 155 171 - T 11-10-2018 IPR018201 Beta-ketoacyl synthase, active site AFK25_03430 3aff59ff7740f700ddf2a5a33fd3070c 413 SUPERFAMILY SSF53901 4 251 5.19E-78 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_03430 3aff59ff7740f700ddf2a5a33fd3070c 413 Gene3D G3DSA:3.40.47.10 256 400 1.1E-58 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_03430 3aff59ff7740f700ddf2a5a33fd3070c 413 TIGRFAM TIGR03150 fabF: beta-ketoacyl-acyl-carrier-protein synthase II 4 409 4.4E-205 T 11-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 AFK25_03430 3aff59ff7740f700ddf2a5a33fd3070c 413 Pfam PF02801 Beta-ketoacyl synthase, C-terminal domain 254 368 4.6E-42 T 11-10-2018 IPR014031 Beta-ketoacyl synthase, C-terminal AFK25_03430 3aff59ff7740f700ddf2a5a33fd3070c 413 PIRSF PIRSF000447 1 413 5.9E-192 T 11-10-2018 IPR017568 3-oxoacyl-[acyl-carrier-protein] synthase 2 GO:0006633|GO:0016747 AFK25_03430 3aff59ff7740f700ddf2a5a33fd3070c 413 SUPERFAMILY SSF53901 214 411 9.72E-79 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_04635 9ae56cbfa3939de0c4804f83f0d5a98d 267 Pfam PF08282 haloacid dehalogenase-like hydrolase 5 252 2.0E-50 T 11-10-2018 AFK25_04635 9ae56cbfa3939de0c4804f83f0d5a98d 267 SUPERFAMILY SSF56784 1 252 2.42E-59 T 11-10-2018 IPR036412 HAD-like superfamily AFK25_04635 9ae56cbfa3939de0c4804f83f0d5a98d 267 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 4 252 4.9E-52 T 11-10-2018 IPR000150 Cof family GO:0016787 AFK25_04635 9ae56cbfa3939de0c4804f83f0d5a98d 267 Gene3D G3DSA:3.30.1240.10 82 188 4.0E-58 T 11-10-2018 AFK25_04635 9ae56cbfa3939de0c4804f83f0d5a98d 267 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 4 232 1.1E-27 T 11-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 AFK25_04635 9ae56cbfa3939de0c4804f83f0d5a98d 267 Gene3D G3DSA:3.40.50.1000 4 252 4.0E-58 T 11-10-2018 IPR023214 HAD superfamily AFK25_11735 3c99d431e60c54b5cdabe49ecd3e4a4c 324 PIRSF PIRSF026567 1 324 2.5E-139 T 11-10-2018 IPR016843 S-adenosyl-L-methionine dependent adenine methyltransferase, bacteria, predicted AFK25_11735 3c99d431e60c54b5cdabe49ecd3e4a4c 324 Gene3D G3DSA:1.10.150.470 1 80 5.1E-28 T 11-10-2018 AFK25_11735 3c99d431e60c54b5cdabe49ecd3e4a4c 324 SUPERFAMILY SSF53335 14 308 4.18E-46 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_11735 3c99d431e60c54b5cdabe49ecd3e4a4c 324 Pfam PF02384 N-6 DNA Methylase 92 290 3.6E-19 T 11-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 AFK25_11735 3c99d431e60c54b5cdabe49ecd3e4a4c 324 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 212 236 2.4E-7 T 11-10-2018 AFK25_11735 3c99d431e60c54b5cdabe49ecd3e4a4c 324 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 116 130 2.4E-7 T 11-10-2018 AFK25_11735 3c99d431e60c54b5cdabe49ecd3e4a4c 324 Gene3D G3DSA:3.40.50.150 82 323 2.6E-56 T 11-10-2018 AFK25_14260 54974acd29b1183c72bfaf7f20e1eeec 240 Gene3D G3DSA:3.40.50.300 1 240 2.7E-81 T 11-10-2018 AFK25_14260 54974acd29b1183c72bfaf7f20e1eeec 240 SUPERFAMILY SSF52540 1 235 1.94E-82 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_14260 54974acd29b1183c72bfaf7f20e1eeec 240 PIRSF PIRSF039085 1 240 3.0E-121 T 11-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 AFK25_14260 54974acd29b1183c72bfaf7f20e1eeec 240 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_14260 54974acd29b1183c72bfaf7f20e1eeec 240 Pfam PF00005 ABC transporter 17 165 3.6E-35 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_14260 54974acd29b1183c72bfaf7f20e1eeec 240 SMART SM00382 26 213 4.9E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_06455 fc34f3710dd8f1a4a05f1d50b200f7e6 727 Gene3D G3DSA:1.20.1220.12 583 726 2.3E-75 T 11-10-2018 AFK25_06455 fc34f3710dd8f1a4a05f1d50b200f7e6 727 Pfam PF01274 Malate synthase 17 696 1.2E-176 T 11-10-2018 IPR001465 Malate synthase GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 AFK25_06455 fc34f3710dd8f1a4a05f1d50b200f7e6 727 Gene3D G3DSA:3.20.20.360 7 579 4.8E-284 T 11-10-2018 AFK25_06455 fc34f3710dd8f1a4a05f1d50b200f7e6 727 Gene3D G3DSA:2.170.170.11 134 263 4.8E-284 T 11-10-2018 IPR023310 Malate synthase G, beta sub-domain GO:0004474 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 AFK25_06455 fc34f3710dd8f1a4a05f1d50b200f7e6 727 SUPERFAMILY SSF51645 3 721 0.0 T 11-10-2018 IPR011076 Malate synthase-like superfamily GO:0003824 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 AFK25_06455 fc34f3710dd8f1a4a05f1d50b200f7e6 727 TIGRFAM TIGR01345 malate_syn_G: malate synthase G 4 721 0.0 T 11-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 AFK25_06455 fc34f3710dd8f1a4a05f1d50b200f7e6 727 Hamap MF_00641 Malate synthase G [glcB]. 1 727 398.943 T 11-10-2018 IPR006253 Malate synthase G GO:0004474|GO:0006097 KEGG: 00620+2.3.3.9|KEGG: 00630+2.3.3.9|MetaCyc: PWY-6969|MetaCyc: PWY-7118|MetaCyc: PWY-7294|MetaCyc: PWY-7295|MetaCyc: PWY-7854 AFK25_07920 010decc87d5df654ae5b8e2750ec37b9 281 Gene3D G3DSA:3.60.110.10 1 281 8.1E-57 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFK25_07920 010decc87d5df654ae5b8e2750ec37b9 281 SUPERFAMILY SSF56317 2 267 2.88E-55 T 11-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AFK25_07920 010decc87d5df654ae5b8e2750ec37b9 281 Pfam PF00795 Carbon-nitrogen hydrolase 4 261 2.4E-27 T 11-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 AFK25_13150 1e205a2eea613273fb824efe995cd1e2 132 PIRSF PIRSF039090 1 128 2.7E-34 T 11-10-2018 IPR003713 Flagellar protein FliS GO:0044780 AFK25_13150 1e205a2eea613273fb824efe995cd1e2 132 TIGRFAM TIGR00208 fliS: flagellar protein FliS 1 119 4.6E-43 T 11-10-2018 IPR003713 Flagellar protein FliS GO:0044780 AFK25_13150 1e205a2eea613273fb824efe995cd1e2 132 Pfam PF02561 Flagellar protein FliS 8 118 1.2E-39 T 11-10-2018 IPR003713 Flagellar protein FliS GO:0044780 AFK25_13150 1e205a2eea613273fb824efe995cd1e2 132 Gene3D G3DSA:1.20.120.340 1 121 1.8E-39 T 11-10-2018 AFK25_13150 1e205a2eea613273fb824efe995cd1e2 132 SUPERFAMILY SSF101116 5 123 6.8E-37 T 11-10-2018 IPR036584 Flagellar protein FliS superfamily GO:0044780 AFK25_05755 69f19cca939579c17f38c1da2a508b84 360 Pfam PF01312 FlhB HrpN YscU SpaS Family 13 353 2.2E-132 T 11-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 AFK25_05755 69f19cca939579c17f38c1da2a508b84 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 16 38 3.8E-41 T 11-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 AFK25_05755 69f19cca939579c17f38c1da2a508b84 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 278 293 3.8E-41 T 11-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 AFK25_05755 69f19cca939579c17f38c1da2a508b84 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 308 329 3.8E-41 T 11-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 AFK25_05755 69f19cca939579c17f38c1da2a508b84 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 214 232 3.8E-41 T 11-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 AFK25_05755 69f19cca939579c17f38c1da2a508b84 360 PRINTS PR00950 Type III secretion system inner membrane S protein family signature 234 251 3.8E-41 T 11-10-2018 IPR006135 Type III secretion system substrate exporter GO:0009306|GO:0016020 AFK25_05755 69f19cca939579c17f38c1da2a508b84 360 SUPERFAMILY SSF160544 250 357 3.92E-42 T 11-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal AFK25_05755 69f19cca939579c17f38c1da2a508b84 360 TIGRFAM TIGR00328 flhB: flagellar biosynthetic protein FlhB 14 359 2.9E-133 T 11-10-2018 IPR006136 Flagellar biosynthetic protein FlhB GO:0015031|GO:0016021|GO:0044780 AFK25_05755 69f19cca939579c17f38c1da2a508b84 360 Gene3D G3DSA:3.40.1690.10 224 360 4.0E-58 T 11-10-2018 IPR029025 Type III secretion system substrate exporter, C-terminal AFK25_04820 4bc3137c882cf5b193997cf97efee5a9 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 121 156 1.4E-9 T 11-10-2018 IPR001451 Hexapeptide repeat AFK25_04820 4bc3137c882cf5b193997cf97efee5a9 236 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 91 119 4.2E-5 T 11-10-2018 IPR001451 Hexapeptide repeat AFK25_04820 4bc3137c882cf5b193997cf97efee5a9 236 Hamap MF_01691 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase [dapH]. 1 235 46.78 T 11-10-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 AFK25_04820 4bc3137c882cf5b193997cf97efee5a9 236 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 165 200 1.3E-10 T 11-10-2018 IPR001451 Hexapeptide repeat AFK25_04820 4bc3137c882cf5b193997cf97efee5a9 236 Gene3D G3DSA:3.30.70.250 2 84 3.1E-35 T 11-10-2018 AFK25_04820 4bc3137c882cf5b193997cf97efee5a9 236 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 174 202 - T 11-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 AFK25_04820 4bc3137c882cf5b193997cf97efee5a9 236 Gene3D G3DSA:2.160.10.10 85 236 4.6E-52 T 11-10-2018 AFK25_04820 4bc3137c882cf5b193997cf97efee5a9 236 TIGRFAM TIGR03532 DapD_Ac: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase 6 236 2.1E-121 T 11-10-2018 IPR019873 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, DapH GO:0009089|GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 AFK25_04820 4bc3137c882cf5b193997cf97efee5a9 236 SUPERFAMILY SSF51161 39 225 6.95E-52 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily AFK25_04820 4bc3137c882cf5b193997cf97efee5a9 236 Pfam PF08503 Tetrahydrodipicolinate succinyltransferase N-terminal 4 87 2.7E-37 T 11-10-2018 IPR013710 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase, N-terminal GO:0047200 KEGG: 00300+2.3.1.89|MetaCyc: PWY-2941 AFK25_09435 2a5556aa9cd9daff07fa4e79a995fd1e 393 TIGRFAM TIGR01696 deoB: phosphopentomutase 7 387 7.0E-206 T 11-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 AFK25_09435 2a5556aa9cd9daff07fa4e79a995fd1e 393 SUPERFAMILY SSF143856 102 218 4.45E-53 T 11-10-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 AFK25_09435 2a5556aa9cd9daff07fa4e79a995fd1e 393 Pfam PF01676 Metalloenzyme superfamily 6 380 4.4E-48 T 11-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 AFK25_09435 2a5556aa9cd9daff07fa4e79a995fd1e 393 Gene3D G3DSA:3.30.70.1250 100 218 4.6E-181 T 11-10-2018 IPR024052 Phosphopentomutase DeoB cap domain superfamily GO:0008973 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 AFK25_09435 2a5556aa9cd9daff07fa4e79a995fd1e 393 Hamap MF_00740 Phosphopentomutase [deoB]. 5 389 56.53 T 11-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 AFK25_09435 2a5556aa9cd9daff07fa4e79a995fd1e 393 PIRSF PIRSF001491 4 393 2.2E-171 T 11-10-2018 IPR010045 Phosphopentomutase GO:0000287|GO:0005737|GO:0008973|GO:0009117|GO:0043094 KEGG: 00030+5.4.2.7|KEGG: 00230+5.4.2.7|MetaCyc: PWY-7180 AFK25_09435 2a5556aa9cd9daff07fa4e79a995fd1e 393 SUPERFAMILY SSF53649 4 392 8.68E-81 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AFK25_09435 2a5556aa9cd9daff07fa4e79a995fd1e 393 Gene3D G3DSA:3.40.720.10 6 389 4.6E-181 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFK25_00975 f210500b6cdc76ff9d9e03bf118a1488 253 Gene3D G3DSA:1.10.490.50 163 253 2.0E-25 T 11-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain AFK25_00975 f210500b6cdc76ff9d9e03bf118a1488 253 SUPERFAMILY SSF46955 3 105 8.06E-29 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily AFK25_00975 f210500b6cdc76ff9d9e03bf118a1488 253 Pfam PF13411 MerR HTH family regulatory protein 3 70 5.0E-18 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_00975 f210500b6cdc76ff9d9e03bf118a1488 253 SMART SM00422 3 72 4.4E-26 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_00975 f210500b6cdc76ff9d9e03bf118a1488 253 Gene3D G3DSA:1.10.1660.10 1 144 2.5E-43 T 11-10-2018 AFK25_00975 f210500b6cdc76ff9d9e03bf118a1488 253 Pfam PF07739 TipAS antibiotic-recognition domain 135 249 1.3E-36 T 11-10-2018 IPR012925 TipAS antibiotic-recognition domain AFK25_00975 f210500b6cdc76ff9d9e03bf118a1488 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 6.7E-7 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_00975 f210500b6cdc76ff9d9e03bf118a1488 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 6.7E-7 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_00975 f210500b6cdc76ff9d9e03bf118a1488 253 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 6.7E-7 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_00975 f210500b6cdc76ff9d9e03bf118a1488 253 SUPERFAMILY SSF89082 163 251 1.83E-28 T 11-10-2018 IPR036244 TipA-like multidrug resistance regulator, antibiotic-recognition domain AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 PRINTS PR00941 Cadmium-transporting ATPase signature 111 123 2.3E-19 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 PRINTS PR00941 Cadmium-transporting ATPase signature 185 201 2.3E-19 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 PRINTS PR00941 Cadmium-transporting ATPase signature 265 279 2.3E-19 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 PRINTS PR00941 Cadmium-transporting ATPase signature 4 13 2.3E-19 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 PRINTS PR00941 Cadmium-transporting ATPase signature 165 185 2.3E-19 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 PRINTS PR00941 Cadmium-transporting ATPase signature 246 262 2.3E-19 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 SUPERFAMILY SSF81653 183 280 7.72E-26 T 11-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 SUPERFAMILY SSF55008 3 57 1.27E-7 T 11-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 SUPERFAMILY SSF56784 379 673 2.89E-53 T 11-10-2018 IPR036412 HAD-like superfamily AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 130 678 4.2E-185 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 154 657 9.5E-91 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 131 468 7.9E-100 T 11-10-2018 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 525 535 2.3E-24 T 11-10-2018 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 230 244 2.3E-24 T 11-10-2018 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 381 395 2.3E-24 T 11-10-2018 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 600 612 2.3E-24 T 11-10-2018 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 502 513 2.3E-24 T 11-10-2018 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 577 596 2.3E-24 T 11-10-2018 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 ProSitePatterns PS01229 Hypothetical cof family signature 2. 577 599 - T 11-10-2018 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 Pfam PF00122 E1-E2 ATPase 181 361 1.5E-54 T 11-10-2018 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 Gene3D G3DSA:2.70.150.20 169 284 4.4E-36 T 11-10-2018 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 Gene3D G3DSA:3.40.1110.10 392 509 2.0E-95 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 Pfam PF00702 haloacid dehalogenase-like hydrolase 377 590 1.1E-46 T 11-10-2018 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 Gene3D G3DSA:3.30.70.100 2 66 2.0E-7 T 11-10-2018 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 SUPERFAMILY SSF81665 131 671 1.11E-23 T 11-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 Gene3D G3DSA:3.40.50.1000 362 628 2.0E-95 T 11-10-2018 IPR023214 HAD superfamily AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 383 389 - T 11-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFK25_07840 0a1d982a5caaf83e097b9eebe4c927d5 686 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 112 679 7.6E-132 T 11-10-2018 AFK25_03545 0284e50d8d889e5c99a3e655a950189c 215 Gene3D G3DSA:3.30.460.10 1 147 7.4E-53 T 11-10-2018 AFK25_03545 0284e50d8d889e5c99a3e655a950189c 215 SUPERFAMILY SSF81301 2 198 1.14E-61 T 11-10-2018 AFK25_03545 0284e50d8d889e5c99a3e655a950189c 215 SMART SM00954 44 165 1.4E-43 T 11-10-2018 IPR007685 RelA/SpoT GO:0015969 AFK25_03545 0284e50d8d889e5c99a3e655a950189c 215 Gene3D G3DSA:1.10.287.860 148 211 6.3E-29 T 11-10-2018 AFK25_03545 0284e50d8d889e5c99a3e655a950189c 215 Pfam PF04607 Region found in RelA / SpoT proteins 44 163 1.7E-38 T 11-10-2018 IPR007685 RelA/SpoT GO:0015969 AFK25_13985 67f0fe4ba21f40e1dd907b23fab2bc86 531 Gene3D G3DSA:3.40.50.300 1 285 2.4E-138 T 11-10-2018 AFK25_13985 67f0fe4ba21f40e1dd907b23fab2bc86 531 Pfam PF06418 CTP synthase N-terminus 3 267 5.8E-133 T 11-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AFK25_13985 67f0fe4ba21f40e1dd907b23fab2bc86 531 TIGRFAM TIGR00337 PyrG: CTP synthase 1 527 1.1E-267 T 11-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AFK25_13985 67f0fe4ba21f40e1dd907b23fab2bc86 531 SUPERFAMILY SSF52317 290 529 4.9E-88 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_13985 67f0fe4ba21f40e1dd907b23fab2bc86 531 Pfam PF00117 Glutamine amidotransferase class-I 302 526 2.0E-59 T 11-10-2018 IPR017926 Glutamine amidotransferase AFK25_13985 67f0fe4ba21f40e1dd907b23fab2bc86 531 Hamap MF_01227 CTP synthase [pyrG]. 2 531 53.268 T 11-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AFK25_13985 67f0fe4ba21f40e1dd907b23fab2bc86 531 Gene3D G3DSA:3.40.50.880 286 531 2.6E-106 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_13985 67f0fe4ba21f40e1dd907b23fab2bc86 531 SUPERFAMILY SSF52540 1 270 7.44E-129 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_09795 9bd45b35f94350389f30ede631a91c1b 259 Gene3D G3DSA:1.10.10.10 140 259 2.5E-54 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_09795 9bd45b35f94350389f30ede631a91c1b 259 ProDom PD010908 TRANSCRIPTION SPORULATION TWO-COMPONENT DNA-BINDING PHOSPHORYLATION SENSORY REGULATION TRANSDUCTION METAL-BINDING CALCIUM 148 258 3.0E-56 T 11-10-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 AFK25_09795 9bd45b35f94350389f30ede631a91c1b 259 Gene3D G3DSA:3.40.50.2300 1 133 1.2E-33 T 11-10-2018 AFK25_09795 9bd45b35f94350389f30ede631a91c1b 259 Pfam PF08769 Sporulation initiation factor Spo0A C terminal 149 252 9.0E-45 T 11-10-2018 IPR014879 Sporulation initiation factor Spo0A, C-terminal GO:0003700|GO:0005509|GO:0005737|GO:0006355|GO:0042173 AFK25_09795 9bd45b35f94350389f30ede631a91c1b 259 SUPERFAMILY SSF52172 3 129 1.07E-33 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_09795 9bd45b35f94350389f30ede631a91c1b 259 TIGRFAM TIGR02875 spore_0_A: sporulation transcription factor Spo0A 3 259 7.1E-126 T 11-10-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 AFK25_09795 9bd45b35f94350389f30ede631a91c1b 259 PIRSF PIRSF002937 1 259 3.2E-127 T 11-10-2018 IPR012052 Sporulation transcription factor Spo0A GO:0003677|GO:0005509|GO:0006355|GO:0043937|GO:0051606 AFK25_09795 9bd45b35f94350389f30ede631a91c1b 259 SUPERFAMILY SSF46894 143 257 3.23E-48 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFK25_09795 9bd45b35f94350389f30ede631a91c1b 259 Pfam PF00072 Response regulator receiver domain 6 118 4.9E-28 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_09795 9bd45b35f94350389f30ede631a91c1b 259 SMART SM00448 4 118 2.2E-32 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_02655 2478a1a82aa45ebeb41dc93dce0b60fa 147 Gene3D G3DSA:1.10.10.10 3 147 1.2E-36 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_02655 2478a1a82aa45ebeb41dc93dce0b60fa 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 2.1E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_02655 2478a1a82aa45ebeb41dc93dce0b60fa 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 2.1E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_02655 2478a1a82aa45ebeb41dc93dce0b60fa 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 2.1E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_02655 2478a1a82aa45ebeb41dc93dce0b60fa 147 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 2.1E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_02655 2478a1a82aa45ebeb41dc93dce0b60fa 147 SUPERFAMILY SSF46785 10 143 1.48E-35 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_02655 2478a1a82aa45ebeb41dc93dce0b60fa 147 Pfam PF01047 MarR family 35 93 5.8E-19 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_02655 2478a1a82aa45ebeb41dc93dce0b60fa 147 SMART SM00529 53 145 0.0071 T 11-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 AFK25_02655 2478a1a82aa45ebeb41dc93dce0b60fa 147 SMART SM00347 28 128 8.2E-32 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_13850 a7b8fa5f98fabec29c64e95a556873bf 178 PRINTS PR00125 ATP synthase delta subunit signature 151 169 4.2E-27 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13850 a7b8fa5f98fabec29c64e95a556873bf 178 PRINTS PR00125 ATP synthase delta subunit signature 74 85 4.2E-27 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13850 a7b8fa5f98fabec29c64e95a556873bf 178 PRINTS PR00125 ATP synthase delta subunit signature 85 99 4.2E-27 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13850 a7b8fa5f98fabec29c64e95a556873bf 178 PRINTS PR00125 ATP synthase delta subunit signature 6 25 4.2E-27 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13850 a7b8fa5f98fabec29c64e95a556873bf 178 PRINTS PR00125 ATP synthase delta subunit signature 136 151 4.2E-27 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13850 a7b8fa5f98fabec29c64e95a556873bf 178 Hamap MF_01416 ATP synthase subunit delta [atpD]. 2 178 20.971 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13850 a7b8fa5f98fabec29c64e95a556873bf 178 SUPERFAMILY SSF47928 3 106 2.35E-24 T 11-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13850 a7b8fa5f98fabec29c64e95a556873bf 178 TIGRFAM TIGR01145 ATP_synt_delta: ATP synthase F1, delta subunit 6 176 9.1E-53 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13850 a7b8fa5f98fabec29c64e95a556873bf 178 Gene3D G3DSA:1.10.520.20 6 97 1.5E-12 T 11-10-2018 IPR026015 F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13850 a7b8fa5f98fabec29c64e95a556873bf 178 Pfam PF00213 ATP synthase delta (OSCP) subunit 6 176 4.0E-49 T 11-10-2018 IPR000711 ATPase, OSCP/delta subunit GO:0015986|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13850 a7b8fa5f98fabec29c64e95a556873bf 178 ProSitePatterns PS00389 ATP synthase delta (OSCP) subunit signature. 138 157 - T 11-10-2018 IPR020781 ATPase, OSCP/delta subunit, conserved site GO:0015986|GO:0016020|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_07390 28f5a07c813d1709d3b84cf8dd3becb6 76 Pfam PF11431 Membrane transport protein MerF 23 66 1.9E-20 T 11-10-2018 IPR021091 Mercury ion transport, MerF AFK25_07390 28f5a07c813d1709d3b84cf8dd3becb6 76 Gene3D G3DSA:1.20.58.2000 1 75 7.8E-28 T 11-10-2018 AFK25_06830 441304d65663c3a2ab31f3023f0730e2 281 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 182 1.0E-66 T 11-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFK25_06830 441304d65663c3a2ab31f3023f0730e2 281 Gene3D G3DSA:3.40.50.720 1 187 1.2E-70 T 11-10-2018 AFK25_06830 441304d65663c3a2ab31f3023f0730e2 281 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 185 280 7.3E-33 T 11-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFK25_06830 441304d65663c3a2ab31f3023f0730e2 281 SUPERFAMILY SSF48179 184 280 1.96E-33 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFK25_06830 441304d65663c3a2ab31f3023f0730e2 281 SUPERFAMILY SSF51735 4 183 4.6E-58 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_06830 441304d65663c3a2ab31f3023f0730e2 281 Gene3D G3DSA:1.10.1040.10 188 281 9.6E-35 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFK25_06830 441304d65663c3a2ab31f3023f0730e2 281 PIRSF PIRSF000105 1 281 3.3E-92 T 11-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 AFK25_10360 74a43a11f776b803a8b4bd8b09a5d353 450 SUPERFAMILY SSF102114 120 363 2.22E-59 T 11-10-2018 AFK25_10360 74a43a11f776b803a8b4bd8b09a5d353 450 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 147 167 - T 11-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 AFK25_10360 74a43a11f776b803a8b4bd8b09a5d353 450 Gene3D G3DSA:3.40.50.12160 3 134 5.9E-25 T 11-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily AFK25_10360 74a43a11f776b803a8b4bd8b09a5d353 450 Gene3D G3DSA:3.80.30.20 140 375 4.0E-88 T 11-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFK25_10360 74a43a11f776b803a8b4bd8b09a5d353 450 Pfam PF04055 Radical SAM superfamily 149 319 4.5E-29 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFK25_10360 74a43a11f776b803a8b4bd8b09a5d353 450 TIGRFAM TIGR01579 MiaB-like-C: MiaB-like tRNA modifying enzyme 6 423 9.4E-144 T 11-10-2018 IPR006467 MiaB-like tRNA modifying enzyme GO:0016740 AFK25_10360 74a43a11f776b803a8b4bd8b09a5d353 450 Pfam PF00919 Uncharacterized protein family UPF0004 4 98 4.0E-26 T 11-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 AFK25_10360 74a43a11f776b803a8b4bd8b09a5d353 450 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 3 431 2.0E-149 T 11-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 AFK25_10360 74a43a11f776b803a8b4bd8b09a5d353 450 SMART SM00729 143 361 9.1E-62 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFK25_05785 a9d2ee6aa8ad91e1ddc24ef978d8eb90 143 Gene3D G3DSA:2.40.50.180 24 133 2.5E-44 T 11-10-2018 AFK25_05785 a9d2ee6aa8ad91e1ddc24ef978d8eb90 143 Gene3D G3DSA:2.30.30.40 7 132 2.5E-44 T 11-10-2018 AFK25_05785 a9d2ee6aa8ad91e1ddc24ef978d8eb90 143 SUPERFAMILY SSF50341 2 139 2.75E-41 T 11-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 AFK25_05785 a9d2ee6aa8ad91e1ddc24ef978d8eb90 143 Pfam PF01584 CheW-like domain 6 140 6.5E-39 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFK25_05785 a9d2ee6aa8ad91e1ddc24ef978d8eb90 143 SMART SM00260 1 138 6.7E-41 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFK25_10950 ebe37eac1d672a8ba733cb2fad6c8f82 230 Gene3D G3DSA:3.30.160.540 11 90 2.9E-26 T 11-10-2018 AFK25_10950 ebe37eac1d672a8ba733cb2fad6c8f82 230 Gene3D G3DSA:2.160.20.70 104 229 3.4E-37 T 11-10-2018 IPR016098 Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal GO:0000902 AFK25_10950 ebe37eac1d672a8ba733cb2fad6c8f82 230 Hamap MF_00267 Probable septum site-determining protein MinC [minC]. 12 214 21.893 T 11-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 AFK25_10950 ebe37eac1d672a8ba733cb2fad6c8f82 230 TIGRFAM TIGR01222 minC: septum site-determining protein MinC 13 213 2.2E-36 T 11-10-2018 IPR013033 Septum formation inhibitor MinC GO:0051726|GO:1901891 AFK25_10950 ebe37eac1d672a8ba733cb2fad6c8f82 230 Pfam PF03775 Septum formation inhibitor MinC, C-terminal domain 111 210 1.6E-31 T 11-10-2018 IPR005526 Septum formation inhibitor MinC, C-terminal GO:0000902 AFK25_10950 ebe37eac1d672a8ba733cb2fad6c8f82 230 SUPERFAMILY SSF63848 110 212 2.48E-30 T 11-10-2018 IPR036145 Septum formation inhibitor MinC, C-terminal domain superfamily GO:0000902 AFK25_08625 d81e9dc2cb74b271fa89921227a2be77 765 Gene3D G3DSA:3.20.20.450 509 761 6.7E-100 T 11-10-2018 IPR035919 EAL domain superfamily AFK25_08625 d81e9dc2cb74b271fa89921227a2be77 765 Gene3D G3DSA:3.30.70.270 329 508 3.5E-59 T 11-10-2018 AFK25_08625 d81e9dc2cb74b271fa89921227a2be77 765 SUPERFAMILY SSF55073 340 498 3.77E-51 T 11-10-2018 IPR029787 Nucleotide cyclase AFK25_08625 d81e9dc2cb74b271fa89921227a2be77 765 SMART SM00267 324 496 6.3E-69 T 11-10-2018 IPR000160 GGDEF domain AFK25_08625 d81e9dc2cb74b271fa89921227a2be77 765 Pfam PF00990 Diguanylate cyclase, GGDEF domain 335 492 8.3E-51 T 11-10-2018 IPR000160 GGDEF domain AFK25_08625 d81e9dc2cb74b271fa89921227a2be77 765 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 333 495 6.1E-49 T 11-10-2018 IPR000160 GGDEF domain AFK25_08625 d81e9dc2cb74b271fa89921227a2be77 765 Pfam PF00563 EAL domain 513 747 6.1E-74 T 11-10-2018 IPR001633 EAL domain AFK25_08625 d81e9dc2cb74b271fa89921227a2be77 765 SUPERFAMILY SSF141868 512 760 9.81E-90 T 11-10-2018 IPR035919 EAL domain superfamily AFK25_08625 d81e9dc2cb74b271fa89921227a2be77 765 SMART SM00052 506 752 2.4E-118 T 11-10-2018 IPR001633 EAL domain AFK25_00010 ddfd714d24887266a0cb0e3717afc098 378 Pfam PF02767 DNA polymerase III beta subunit, central domain 137 251 4.5E-40 T 11-10-2018 IPR022637 DNA polymerase III, beta sliding clamp, central GO:0003887|GO:0006260|GO:0008408|GO:0009360 AFK25_00010 ddfd714d24887266a0cb0e3717afc098 378 SUPERFAMILY SSF55979 2 127 4.71E-23 T 11-10-2018 AFK25_00010 ddfd714d24887266a0cb0e3717afc098 378 Gene3D G3DSA:3.10.150.10 2 250 7.7E-137 T 11-10-2018 AFK25_00010 ddfd714d24887266a0cb0e3717afc098 378 Pfam PF00712 DNA polymerase III beta subunit, N-terminal domain 2 127 9.2E-37 T 11-10-2018 IPR022634 DNA polymerase III, beta sliding clamp, N-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 AFK25_00010 ddfd714d24887266a0cb0e3717afc098 378 SUPERFAMILY SSF55979 134 251 1.91E-28 T 11-10-2018 AFK25_00010 ddfd714d24887266a0cb0e3717afc098 378 TIGRFAM TIGR00663 dnan: DNA polymerase III, beta subunit 1 377 6.2E-126 T 11-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 AFK25_00010 ddfd714d24887266a0cb0e3717afc098 378 PIRSF PIRSF000804 1 378 7.3E-118 T 11-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 AFK25_00010 ddfd714d24887266a0cb0e3717afc098 378 SMART SM00480 17 373 3.5E-172 T 11-10-2018 IPR001001 DNA polymerase III, beta sliding clamp GO:0003677|GO:0006260|GO:0009360 AFK25_00010 ddfd714d24887266a0cb0e3717afc098 378 SUPERFAMILY SSF55979 254 377 3.87E-32 T 11-10-2018 AFK25_00010 ddfd714d24887266a0cb0e3717afc098 378 Pfam PF02768 DNA polymerase III beta subunit, C-terminal domain 254 376 1.2E-37 T 11-10-2018 IPR022635 DNA polymerase III, beta sliding clamp, C-terminal GO:0003677|GO:0003887|GO:0006260|GO:0008408|GO:0009360 AFK25_00010 ddfd714d24887266a0cb0e3717afc098 378 Gene3D G3DSA:3.70.10.10 145 375 7.7E-137 T 11-10-2018 AFK25_06365 25270a6fcc79c92b0ec725cdd9dea282 440 Pfam PF13353 4Fe-4S single cluster domain 96 207 1.8E-5 T 11-10-2018 AFK25_06365 25270a6fcc79c92b0ec725cdd9dea282 440 SUPERFAMILY SSF102114 88 402 2.35E-37 T 11-10-2018 AFK25_06365 25270a6fcc79c92b0ec725cdd9dea282 440 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 331 413 4.1E-11 T 11-10-2018 IPR023885 4Fe4S-binding SPASM domain AFK25_06365 25270a6fcc79c92b0ec725cdd9dea282 440 Gene3D G3DSA:3.20.20.70 87 439 3.1E-53 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_06365 25270a6fcc79c92b0ec725cdd9dea282 440 Pfam PF04055 Radical SAM superfamily 94 233 6.4E-11 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFK25_00630 03ab778bedbe6eff4c7e36b1e78b9e7d 113 Hamap MF_01331_B 50S ribosomal protein L22 [rplV]. 1 110 30.991 T 11-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00630 03ab778bedbe6eff4c7e36b1e78b9e7d 113 Gene3D G3DSA:3.90.470.10 1 113 3.1E-51 T 11-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 AFK25_00630 03ab778bedbe6eff4c7e36b1e78b9e7d 113 TIGRFAM TIGR01044 rplV_bact: ribosomal protein uL22 5 107 1.4E-52 T 11-10-2018 IPR005727 Ribosomal protein L22, bacterial/chloroplast-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00630 03ab778bedbe6eff4c7e36b1e78b9e7d 113 Pfam PF00237 Ribosomal protein L22p/L17e 5 107 1.4E-38 T 11-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 AFK25_00630 03ab778bedbe6eff4c7e36b1e78b9e7d 113 SUPERFAMILY SSF54843 1 112 2.62E-45 T 11-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 AFK25_00630 03ab778bedbe6eff4c7e36b1e78b9e7d 113 ProSitePatterns PS00464 Ribosomal protein L22 signature. 83 107 - T 11-10-2018 IPR018260 Ribosomal protein L22/L17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 SMART SM00387 389 532 2.6E-28 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 SUPERFAMILY SSF47384 285 345 4.71E-15 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 SUPERFAMILY SSF55052 157 240 2.28E-24 T 11-10-2018 IPR035891 CheY-binding domain of CheA AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 PRINTS PR00344 Bacterial sensor protein C-terminal signature 434 448 8.0E-15 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 PRINTS PR00344 Bacterial sensor protein C-terminal signature 516 529 8.0E-15 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 510 8.0E-15 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 285 343 1.9E-13 T 11-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 Gene3D G3DSA:3.30.565.10 345 531 1.4E-62 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 SUPERFAMILY SSF47226 2 125 2.22E-35 T 11-10-2018 IPR036641 HPT domain superfamily GO:0000160 AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 Pfam PF07194 P2 response regulator binding domain 161 239 9.5E-26 T 11-10-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 SMART SM00260 524 663 3.5E-39 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 SMART SM01231 284 344 4.4E-19 T 11-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 Gene3D G3DSA:1.20.120.160 1 141 3.8E-43 T 11-10-2018 IPR036641 HPT domain superfamily GO:0000160 AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 Gene3D G3DSA:2.30.30.40 532 658 5.9E-39 T 11-10-2018 AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 SUPERFAMILY SSF50341 531 663 2.09E-32 T 11-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 Pfam PF01627 Hpt domain 5 98 8.5E-21 T 11-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 Gene3D G3DSA:2.40.50.180 555 618 5.9E-39 T 11-10-2018 AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 Gene3D G3DSA:1.10.287.560 284 344 1.0E-19 T 11-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 SUPERFAMILY SSF55874 346 530 8.38E-44 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 Gene3D G3DSA:3.30.70.1110 157 241 8.1E-30 T 11-10-2018 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 SMART SM00073 3 100 5.8E-42 T 11-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 Pfam PF01584 CheW-like domain 537 663 5.7E-25 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFK25_05780 78d12b0d4f7b9135a80176afc166c3d8 664 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 392 531 5.6E-18 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_07855 f7ffdcfce2a804afe45a4b403c6465f5 342 Pfam PF03445 Putative nucleotidyltransferase DUF294 44 166 3.5E-31 T 11-10-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 AFK25_07855 f7ffdcfce2a804afe45a4b403c6465f5 342 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 210 338 1.5E-22 T 11-10-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding AFK25_02200 a54fc3cc8ec6c19cfabc73d72f0b6568 378 Hamap MF_00916 Epoxyqueuosine reductase [queG]. 3 309 43.7 T 11-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 AFK25_02200 a54fc3cc8ec6c19cfabc73d72f0b6568 378 TIGRFAM TIGR00276 TIGR00276: epoxyqueuosine reductase 10 342 5.3E-131 T 11-10-2018 IPR004453 Epoxyqueuosine reductase QueG GO:0008033|GO:0008616|GO:0016491 MetaCyc: PWY-6700 AFK25_02200 a54fc3cc8ec6c19cfabc73d72f0b6568 378 SUPERFAMILY SSF48371 263 374 1.39E-13 T 11-10-2018 IPR016024 Armadillo-type fold AFK25_02200 a54fc3cc8ec6c19cfabc73d72f0b6568 378 Gene3D G3DSA:1.25.10.10 263 378 3.8E-12 T 11-10-2018 IPR011989 Armadillo-like helical AFK25_02200 a54fc3cc8ec6c19cfabc73d72f0b6568 378 Pfam PF13646 HEAT repeats 300 373 1.3E-12 T 11-10-2018 AFK25_02200 a54fc3cc8ec6c19cfabc73d72f0b6568 378 Pfam PF08331 Domain of unknown function (DUF1730) 57 135 8.6E-18 T 11-10-2018 IPR013542 Domain of unknown function DUF1730 MetaCyc: PWY-6700 AFK25_02200 a54fc3cc8ec6c19cfabc73d72f0b6568 378 SUPERFAMILY SSF54862 164 254 3.43E-15 T 11-10-2018 AFK25_02200 a54fc3cc8ec6c19cfabc73d72f0b6568 378 SMART SM00567 E-Z type HEAT repeats 298 327 290.0 T 11-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 AFK25_02200 a54fc3cc8ec6c19cfabc73d72f0b6568 378 SMART SM00567 E-Z type HEAT repeats 330 359 5.2E-4 T 11-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 AFK25_02200 a54fc3cc8ec6c19cfabc73d72f0b6568 378 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 188 199 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFK25_02200 a54fc3cc8ec6c19cfabc73d72f0b6568 378 Pfam PF13484 4Fe-4S double cluster binding domain 188 250 6.9E-17 T 11-10-2018 AFK25_04845 6bf3fb3628b471a9acf10389f64555d4 71 Hamap MF_01553 UPF0356 protein . 1 69 22.889 T 11-10-2018 IPR009907 Protein of unknown function DUF1447 AFK25_04845 6bf3fb3628b471a9acf10389f64555d4 71 ProDom PD055417 UPF0356 TRANSCRIPTIONAL REGULATOR SP0122 SH1862 BLI01669/BL01628 MW0973 LMOF2365_1049 BCE33L3734 SPYM3_1619/SPS0248 1 68 7.0E-25 T 11-10-2018 IPR009907 Protein of unknown function DUF1447 AFK25_04845 6bf3fb3628b471a9acf10389f64555d4 71 Gene3D G3DSA:3.10.20.730 1 58 2.5E-29 T 11-10-2018 AFK25_04845 6bf3fb3628b471a9acf10389f64555d4 71 Pfam PF07288 Protein of unknown function (DUF1447) 2 68 9.3E-31 T 11-10-2018 IPR009907 Protein of unknown function DUF1447 AFK25_10645 3226bb4824af7152d461ab6a91113941 211 Hamap MF_00551 Uridine kinase [udk]. 2 206 42.699 T 11-10-2018 IPR026008 Uridine kinase GO:0004849|GO:0005524|GO:0016773 KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193 AFK25_10645 3226bb4824af7152d461ab6a91113941 211 Gene3D G3DSA:3.40.50.300 1 211 2.4E-68 T 11-10-2018 AFK25_10645 3226bb4824af7152d461ab6a91113941 211 PRINTS PR00988 Uridine kinase signature 35 46 4.4E-37 T 11-10-2018 AFK25_10645 3226bb4824af7152d461ab6a91113941 211 PRINTS PR00988 Uridine kinase signature 150 161 4.4E-37 T 11-10-2018 AFK25_10645 3226bb4824af7152d461ab6a91113941 211 PRINTS PR00988 Uridine kinase signature 172 185 4.4E-37 T 11-10-2018 AFK25_10645 3226bb4824af7152d461ab6a91113941 211 PRINTS PR00988 Uridine kinase signature 80 95 4.4E-37 T 11-10-2018 AFK25_10645 3226bb4824af7152d461ab6a91113941 211 PRINTS PR00988 Uridine kinase signature 136 146 4.4E-37 T 11-10-2018 AFK25_10645 3226bb4824af7152d461ab6a91113941 211 PRINTS PR00988 Uridine kinase signature 5 22 4.4E-37 T 11-10-2018 AFK25_10645 3226bb4824af7152d461ab6a91113941 211 Pfam PF00485 Phosphoribulokinase / Uridine kinase family 7 192 1.3E-43 T 11-10-2018 IPR006083 Phosphoribulokinase/uridine kinase GO:0005524|GO:0016301 Reactome: R-HSA-73614 AFK25_10645 3226bb4824af7152d461ab6a91113941 211 TIGRFAM TIGR00235 udk: uridine kinase 3 206 6.7E-94 T 11-10-2018 IPR000764 Uridine kinase-like KEGG: 00240+2.7.1.48|KEGG: 00983+2.7.1.48|MetaCyc: PWY-7193|Reactome: R-HSA-73614 AFK25_10645 3226bb4824af7152d461ab6a91113941 211 SUPERFAMILY SSF52540 3 197 2.59E-51 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_11800 23cff6ac876da7a8efec34b6c4868dbb 64 Gene3D G3DSA:1.10.8.910 5 64 4.4E-32 T 11-10-2018 IPR038300 SASP, alpha/beta-type superfamily AFK25_11800 23cff6ac876da7a8efec34b6c4868dbb 64 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 38 52 - T 11-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 AFK25_11800 23cff6ac876da7a8efec34b6c4868dbb 64 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 5 59 1.5E-23 T 11-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 AFK25_11800 23cff6ac876da7a8efec34b6c4868dbb 64 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 20 29 - T 11-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 AFK25_04135 92dc03074bda59aad471f3daf972b438 449 Pfam PF02954 Bacterial regulatory protein, Fis family 407 447 2.9E-11 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFK25_04135 92dc03074bda59aad471f3daf972b438 449 ProSitePatterns PS00676 Sigma-54 interaction domain ATP-binding region B signature. 231 246 - T 11-10-2018 IPR025943 Sigma-54 interaction domain, ATP-binding site 2 AFK25_04135 92dc03074bda59aad471f3daf972b438 449 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 430 449 5.3E-9 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFK25_04135 92dc03074bda59aad471f3daf972b438 449 PRINTS PR01590 FIS bacterial regulatory protein HTH signature 413 430 5.3E-9 T 11-10-2018 IPR002197 DNA binding HTH domain, Fis-type GO:0043565 AFK25_04135 92dc03074bda59aad471f3daf972b438 449 Gene3D G3DSA:1.10.10.60 396 449 1.3E-15 T 11-10-2018 AFK25_04135 92dc03074bda59aad471f3daf972b438 449 Pfam PF00989 PAS fold 8 65 1.6E-9 T 11-10-2018 IPR013767 PAS fold GO:0006355 AFK25_04135 92dc03074bda59aad471f3daf972b438 449 SUPERFAMILY SSF52540 144 389 3.3E-73 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_04135 92dc03074bda59aad471f3daf972b438 449 Gene3D G3DSA:1.10.8.60 316 395 7.1E-27 T 11-10-2018 AFK25_04135 92dc03074bda59aad471f3daf972b438 449 SUPERFAMILY SSF55785 7 100 4.54E-15 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_04135 92dc03074bda59aad471f3daf972b438 449 Gene3D G3DSA:3.40.50.300 130 315 2.1E-66 T 11-10-2018 AFK25_04135 92dc03074bda59aad471f3daf972b438 449 Pfam PF00158 Sigma-54 interaction domain 144 310 9.2E-72 T 11-10-2018 IPR002078 RNA polymerase sigma factor 54 interaction domain GO:0005524|GO:0006355|GO:0008134 AFK25_04135 92dc03074bda59aad471f3daf972b438 449 SUPERFAMILY SSF46689 358 449 1.03E-12 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_04135 92dc03074bda59aad471f3daf972b438 449 SMART SM00382 164 308 1.2E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_04135 92dc03074bda59aad471f3daf972b438 449 ProSitePatterns PS00675 Sigma-54 interaction domain ATP-binding region A signature. 168 181 - T 11-10-2018 IPR025662 Sigma-54 interaction domain, ATP-binding site 1 AFK25_04135 92dc03074bda59aad471f3daf972b438 449 ProSitePatterns PS00688 Sigma-54 interaction domain C-terminal part signature. 358 367 - T 11-10-2018 IPR025944 Sigma-54 interaction domain, conserved site AFK25_04135 92dc03074bda59aad471f3daf972b438 449 SMART SM00091 6 72 1.2E-8 T 11-10-2018 IPR000014 PAS domain AFK25_04135 92dc03074bda59aad471f3daf972b438 449 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 6 58 8.4E-10 T 11-10-2018 IPR000014 PAS domain AFK25_04135 92dc03074bda59aad471f3daf972b438 449 Gene3D G3DSA:3.30.450.20 4 107 1.0E-16 T 11-10-2018 AFK25_00035 c8c9cc399ce600ec88483fddc5385856 361 SMART SM00471 139 275 4.3E-6 T 11-10-2018 IPR003607 HD/PDEase domain AFK25_00035 c8c9cc399ce600ec88483fddc5385856 361 Pfam PF13487 HD domain 195 256 9.6E-13 T 11-10-2018 AFK25_00035 c8c9cc399ce600ec88483fddc5385856 361 Gene3D G3DSA:1.10.3210.10 2 308 1.4E-63 T 11-10-2018 AFK25_00035 c8c9cc399ce600ec88483fddc5385856 361 SUPERFAMILY SSF109604 134 304 1.86E-26 T 11-10-2018 AFK25_14565 258a64c16c6b7662765159c5ac543f8d 149 TIGRFAM TIGR00158 L9: ribosomal protein bL9 1 147 2.4E-52 T 11-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_14565 258a64c16c6b7662765159c5ac543f8d 149 ProSitePatterns PS00651 Ribosomal protein L9 signature. 13 40 - T 11-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_14565 258a64c16c6b7662765159c5ac543f8d 149 Gene3D G3DSA:3.10.430.100 60 149 1.4E-34 T 11-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily AFK25_14565 258a64c16c6b7662765159c5ac543f8d 149 SUPERFAMILY SSF55658 1 56 2.44E-18 T 11-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal AFK25_14565 258a64c16c6b7662765159c5ac543f8d 149 Pfam PF01281 Ribosomal protein L9, N-terminal domain 1 47 4.6E-24 T 11-10-2018 IPR020070 Ribosomal protein L9, N-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_14565 258a64c16c6b7662765159c5ac543f8d 149 Hamap MF_00503 50S ribosomal protein L9 [rplI]. 1 148 26.747 T 11-10-2018 IPR020594 Ribosomal protein L9, bacteria/chloroplast GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_14565 258a64c16c6b7662765159c5ac543f8d 149 SUPERFAMILY SSF55653 56 148 6.15E-31 T 11-10-2018 IPR036791 Ribosomal protein L9, C-terminal domain superfamily AFK25_14565 258a64c16c6b7662765159c5ac543f8d 149 Pfam PF03948 Ribosomal protein L9, C-terminal domain 64 146 8.4E-32 T 11-10-2018 IPR020069 Ribosomal protein L9, C-terminal AFK25_14565 258a64c16c6b7662765159c5ac543f8d 149 Gene3D G3DSA:3.40.5.10 1 52 2.5E-27 T 11-10-2018 IPR036935 Ribosomal protein L9, N-terminal domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_12960 51ead2b1b2e49d39a4724534f3459fe6 296 Pfam PF03668 P-loop ATPase protein family 8 291 1.7E-128 T 11-10-2018 IPR005337 RapZ-like family GO:0005524 AFK25_12960 51ead2b1b2e49d39a4724534f3459fe6 296 SUPERFAMILY SSF52540 10 162 1.65E-13 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_12960 51ead2b1b2e49d39a4724534f3459fe6 296 Gene3D G3DSA:3.40.50.300 7 169 1.9E-6 T 11-10-2018 AFK25_12960 51ead2b1b2e49d39a4724534f3459fe6 296 Hamap MF_00636 RNase adapter protein RapZ [rapZ]. 8 290 42.225 T 11-10-2018 IPR005337 RapZ-like family GO:0005524 AFK25_12960 51ead2b1b2e49d39a4724534f3459fe6 296 PIRSF PIRSF005052 8 293 4.3E-109 T 11-10-2018 IPR005337 RapZ-like family GO:0005524 AFK25_00580 f1a7414906f9314e6b3365a306d26aab 140 Hamap MF_00403_B 30S ribosomal protein S12 [rpsL]. 1 136 41.143 T 11-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00580 f1a7414906f9314e6b3365a306d26aab 140 Pfam PF00164 Ribosomal protein S12/S23 32 136 6.0E-38 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00580 f1a7414906f9314e6b3365a306d26aab 140 TIGRFAM TIGR00981 rpsL_bact: ribosomal protein uS12 1 137 9.2E-69 T 11-10-2018 IPR005679 Ribosomal protein S12, bacterial-type GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00580 f1a7414906f9314e6b3365a306d26aab 140 SUPERFAMILY SSF50249 2 136 2.83E-49 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_00580 f1a7414906f9314e6b3365a306d26aab 140 PRINTS PR01034 Ribosomal protein S12 signature 123 135 1.8E-59 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00580 f1a7414906f9314e6b3365a306d26aab 140 PRINTS PR01034 Ribosomal protein S12 signature 55 70 1.8E-59 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00580 f1a7414906f9314e6b3365a306d26aab 140 PRINTS PR01034 Ribosomal protein S12 signature 40 55 1.8E-59 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00580 f1a7414906f9314e6b3365a306d26aab 140 PRINTS PR01034 Ribosomal protein S12 signature 107 123 1.8E-59 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00580 f1a7414906f9314e6b3365a306d26aab 140 PRINTS PR01034 Ribosomal protein S12 signature 90 107 1.8E-59 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00580 f1a7414906f9314e6b3365a306d26aab 140 PRINTS PR01034 Ribosomal protein S12 signature 71 90 1.8E-59 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00580 f1a7414906f9314e6b3365a306d26aab 140 PIRSF PIRSF002133 1 137 4.0E-49 T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00580 f1a7414906f9314e6b3365a306d26aab 140 Gene3D G3DSA:2.40.50.140 1 140 9.2E-63 T 11-10-2018 AFK25_00580 f1a7414906f9314e6b3365a306d26aab 140 ProSitePatterns PS00055 Ribosomal protein S12 signature. 56 63 - T 11-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_14240 b8cc36a66cb2701d6bbfc6f3e12fd55d 276 Gene3D G3DSA:2.30.24.10 3 57 1.7E-22 T 11-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 AFK25_14240 b8cc36a66cb2701d6bbfc6f3e12fd55d 276 Pfam PF03123 CAT RNA binding domain 4 57 1.6E-21 T 11-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 AFK25_14240 b8cc36a66cb2701d6bbfc6f3e12fd55d 276 ProSitePatterns PS00654 PRD domain signature. 97 109 - T 11-10-2018 IPR001550 Transcription antiterminator, conserved site GO:0003723|GO:0045893 AFK25_14240 b8cc36a66cb2701d6bbfc6f3e12fd55d 276 SUPERFAMILY SSF63520 53 164 1.7E-31 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 AFK25_14240 b8cc36a66cb2701d6bbfc6f3e12fd55d 276 SMART SM01061 3 62 1.5E-25 T 11-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 AFK25_14240 b8cc36a66cb2701d6bbfc6f3e12fd55d 276 SUPERFAMILY SSF63520 170 273 9.94E-29 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 AFK25_14240 b8cc36a66cb2701d6bbfc6f3e12fd55d 276 Gene3D G3DSA:1.10.1790.10 168 276 1.9E-27 T 11-10-2018 AFK25_14240 b8cc36a66cb2701d6bbfc6f3e12fd55d 276 SUPERFAMILY SSF50151 4 55 1.44E-17 T 11-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 AFK25_14240 b8cc36a66cb2701d6bbfc6f3e12fd55d 276 Pfam PF00874 PRD domain 181 272 2.6E-23 T 11-10-2018 IPR011608 PRD domain GO:0006355 AFK25_14240 b8cc36a66cb2701d6bbfc6f3e12fd55d 276 Pfam PF00874 PRD domain 74 161 1.5E-25 T 11-10-2018 IPR011608 PRD domain GO:0006355 AFK25_14240 b8cc36a66cb2701d6bbfc6f3e12fd55d 276 Gene3D G3DSA:1.10.1790.10 64 165 1.9E-33 T 11-10-2018 AFK25_10640 20fdf38c136ab68520182c94ae884016 158 Gene3D G3DSA:3.10.50.30 79 158 1.1E-26 T 11-10-2018 IPR036953 Transcription elongation factor GreA/GreB, C-terminal domain superfamily GO:0003677|GO:0032784 AFK25_10640 20fdf38c136ab68520182c94ae884016 158 Pfam PF03449 Transcription elongation factor, N-terminal 8 77 1.8E-32 T 11-10-2018 IPR022691 Transcription elongation factor, GreA/GreB, N-terminal GO:0003677|GO:0032784 AFK25_10640 20fdf38c136ab68520182c94ae884016 158 ProSitePatterns PS00830 Prokaryotic transcription elongation factors signature 2. 123 139 - T 11-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 AFK25_10640 20fdf38c136ab68520182c94ae884016 158 SUPERFAMILY SSF54534 84 157 3.92E-22 T 11-10-2018 AFK25_10640 20fdf38c136ab68520182c94ae884016 158 Hamap MF_00105 Transcription elongation factor GreA [greA]. 5 158 33.258 T 11-10-2018 IPR028624 Transcription elongation factor GreA/GreB GO:0003677|GO:0032784|GO:0070063 AFK25_10640 20fdf38c136ab68520182c94ae884016 158 SUPERFAMILY SSF46557 5 79 8.11E-28 T 11-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 AFK25_10640 20fdf38c136ab68520182c94ae884016 158 PIRSF PIRSF006092 1 158 2.0E-55 T 11-10-2018 IPR023459 Transcription elongation factor GreA/GreB family GO:0070063 AFK25_10640 20fdf38c136ab68520182c94ae884016 158 ProSitePatterns PS00829 Prokaryotic transcription elongation factors signature 1. 20 51 - T 11-10-2018 IPR018151 Transcription elongation factor, GreA/GreB, conserved site GO:0003677|GO:0032784 AFK25_10640 20fdf38c136ab68520182c94ae884016 158 TIGRFAM TIGR01462 greA: transcription elongation factor GreA 8 158 6.6E-60 T 11-10-2018 IPR006359 Transcription elongation factor GreA GO:0003677|GO:0032784 AFK25_10640 20fdf38c136ab68520182c94ae884016 158 Pfam PF01272 Transcription elongation factor, GreA/GreB, C-term 84 158 3.5E-28 T 11-10-2018 IPR001437 Transcription elongation factor, GreA/GreB, C-terminal GO:0003677|GO:0032784 AFK25_10640 20fdf38c136ab68520182c94ae884016 158 Gene3D G3DSA:1.10.287.180 4 78 8.2E-32 T 11-10-2018 IPR036805 Transcription elongation factor, GreA/GreB, N-terminal domain superfamily GO:0003677|GO:0032784 AFK25_13305 2c6f1860fb43a0b57e2a956d2e8275bf 212 Pfam PF01205 Uncharacterized protein family UPF0029 20 123 7.7E-33 T 11-10-2018 IPR001498 Impact, N-terminal AFK25_13305 2c6f1860fb43a0b57e2a956d2e8275bf 212 SUPERFAMILY SSF54980 135 199 1.94E-11 T 11-10-2018 IPR035647 EF-G domain III/V-like AFK25_13305 2c6f1860fb43a0b57e2a956d2e8275bf 212 TIGRFAM TIGR00257 IMPACT_YIGZ: uncharacterized protein, YigZ family 2 202 1.1E-78 T 11-10-2018 IPR015796 Impact family, bacterial/archaeal AFK25_13305 2c6f1860fb43a0b57e2a956d2e8275bf 212 SUPERFAMILY SSF54211 3 131 1.97E-45 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFK25_13305 2c6f1860fb43a0b57e2a956d2e8275bf 212 Pfam PF09186 Domain of unknown function (DUF1949) 141 195 1.8E-19 T 11-10-2018 IPR015269 Uncharacterised domain UPF0029, Impact, C-terminal AFK25_13305 2c6f1860fb43a0b57e2a956d2e8275bf 212 Gene3D G3DSA:3.30.230.30 1 133 3.3E-52 T 11-10-2018 IPR036956 Impact, N-terminal domain superfamily AFK25_13305 2c6f1860fb43a0b57e2a956d2e8275bf 212 ProSitePatterns PS00910 Uncharacterized protein family UPF0029 signature. 79 108 - T 11-10-2018 IPR020569 Uncharacterised protein family UPF0029, Impact, conserved site AFK25_04925 6cc7acd5635d239fbd0ebb4a12092bf8 319 Pfam PF03060 Nitronate monooxygenase 5 75 1.3E-19 T 11-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 AFK25_04925 6cc7acd5635d239fbd0ebb4a12092bf8 319 Pfam PF03060 Nitronate monooxygenase 78 309 1.5E-52 T 11-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 AFK25_04925 6cc7acd5635d239fbd0ebb4a12092bf8 319 SUPERFAMILY SSF51412 2 316 1.83E-69 T 11-10-2018 AFK25_04925 6cc7acd5635d239fbd0ebb4a12092bf8 319 Gene3D G3DSA:3.20.20.70 2 318 5.4E-110 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_00565 63d33dd0b1eb28d189afac1705ce78a0 1186 Pfam PF10385 RNA polymerase beta subunit external 1 domain 547 614 1.7E-25 T 11-10-2018 IPR019462 DNA-directed RNA polymerase, beta subunit, external 1 domain GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00565 63d33dd0b1eb28d189afac1705ce78a0 1186 Gene3D G3DSA:3.90.1110.10 153 260 1.7E-7 T 11-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00565 63d33dd0b1eb28d189afac1705ce78a0 1186 Pfam PF04563 RNA polymerase beta subunit 28 454 1.8E-30 T 11-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00565 63d33dd0b1eb28d189afac1705ce78a0 1186 Pfam PF04561 RNA polymerase Rpb2, domain 2 369 410 5.4E-7 T 11-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00565 63d33dd0b1eb28d189afac1705ce78a0 1186 Pfam PF04561 RNA polymerase Rpb2, domain 2 140 288 2.5E-26 T 11-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00565 63d33dd0b1eb28d189afac1705ce78a0 1186 Pfam PF04560 RNA polymerase Rpb2, domain 7 1071 1145 3.7E-27 T 11-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00565 63d33dd0b1eb28d189afac1705ce78a0 1186 Gene3D G3DSA:3.90.1100.10 20 152 5.2E-55 T 11-10-2018 AFK25_00565 63d33dd0b1eb28d189afac1705ce78a0 1186 Gene3D G3DSA:3.90.1100.10 390 594 3.1E-76 T 11-10-2018 AFK25_00565 63d33dd0b1eb28d189afac1705ce78a0 1186 Pfam PF00562 RNA polymerase Rpb2, domain 6 676 1069 4.1E-166 T 11-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00565 63d33dd0b1eb28d189afac1705ce78a0 1186 Gene3D G3DSA:2.40.270.10 981 1047 1.9E-24 T 11-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00565 63d33dd0b1eb28d189afac1705ce78a0 1186 Gene3D G3DSA:3.90.1800.10 1057 1110 1.1E-10 T 11-10-2018 AFK25_00565 63d33dd0b1eb28d189afac1705ce78a0 1186 Gene3D G3DSA:2.40.50.150 791 930 1.1E-61 T 11-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00565 63d33dd0b1eb28d189afac1705ce78a0 1186 Pfam PF04565 RNA polymerase Rpb2, domain 3 469 537 3.7E-31 T 11-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00565 63d33dd0b1eb28d189afac1705ce78a0 1186 ProSitePatterns PS01166 RNA polymerases beta chain signature. 922 934 - T 11-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00565 63d33dd0b1eb28d189afac1705ce78a0 1186 Gene3D G3DSA:2.40.270.10 752 790 5.7E-7 T 11-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00565 63d33dd0b1eb28d189afac1705ce78a0 1186 SUPERFAMILY SSF64484 13 1155 0.0 T 11-10-2018 AFK25_00565 63d33dd0b1eb28d189afac1705ce78a0 1186 Gene3D G3DSA:3.90.1100.10 605 671 2.9E-20 T 11-10-2018 AFK25_00565 63d33dd0b1eb28d189afac1705ce78a0 1186 TIGRFAM TIGR02013 rpoB: DNA-directed RNA polymerase, beta subunit 204 896 0.0 T 11-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00565 63d33dd0b1eb28d189afac1705ce78a0 1186 Hamap MF_01321 DNA-directed RNA polymerase subunit beta [rpoB]. 15 1147 12.689 T 11-10-2018 IPR010243 DNA-directed RNA polymerase beta subunit, bacterial-type GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00565 63d33dd0b1eb28d189afac1705ce78a0 1186 Gene3D G3DSA:2.40.50.100 672 751 1.6E-28 T 11-10-2018 AFK25_02175 ee54fbf4aa32da05d8d257a325f4861e 141 Gene3D G3DSA:1.10.10.10 2 139 2.9E-25 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_02175 ee54fbf4aa32da05d8d257a325f4861e 141 SUPERFAMILY SSF46785 23 136 1.18E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_02175 ee54fbf4aa32da05d8d257a325f4861e 141 Pfam PF01047 MarR family 29 87 2.0E-11 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_02175 ee54fbf4aa32da05d8d257a325f4861e 141 SMART SM00347 22 122 5.5E-16 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_02725 cf87d562e82e980fac04dd40bf704a7c 262 SUPERFAMILY SSF53613 4 259 5.14E-85 T 11-10-2018 IPR029056 Ribokinase-like AFK25_02725 cf87d562e82e980fac04dd40bf704a7c 262 Pfam PF08543 Phosphomethylpyrimidine kinase 12 256 1.5E-100 T 11-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 AFK25_02725 cf87d562e82e980fac04dd40bf704a7c 262 TIGRFAM TIGR00097 HMP-P_kinase: hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase 5 258 2.0E-109 T 11-10-2018 IPR004399 Hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase GO:0008972|GO:0009228 KEGG: 00730+2.7.1.49|MetaCyc: PWY-6910|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFK25_02725 cf87d562e82e980fac04dd40bf704a7c 262 Gene3D G3DSA:3.40.1190.20 1 262 7.9E-108 T 11-10-2018 IPR029056 Ribokinase-like AFK25_04290 f7ec46f20c85f84a57e56f5462ed5869 223 SUPERFAMILY SSF56784 5 211 1.26E-51 T 11-10-2018 IPR036412 HAD-like superfamily AFK25_04290 f7ec46f20c85f84a57e56f5462ed5869 223 TIGRFAM TIGR01990 bPGM: beta-phosphoglucomutase 5 193 1.2E-86 T 11-10-2018 IPR010972 Beta-phosphoglucomutase GO:0000287|GO:0005975|GO:0008801 KEGG: 00500+5.4.2.6|MetaCyc: PWY-2721|MetaCyc: PWY-2722|MetaCyc: PWY-7459 AFK25_04290 f7ec46f20c85f84a57e56f5462ed5869 223 Pfam PF13419 Haloacid dehalogenase-like hydrolase 8 192 1.1E-28 T 11-10-2018 AFK25_04290 f7ec46f20c85f84a57e56f5462ed5869 223 Gene3D G3DSA:3.40.50.1000 6 206 5.3E-75 T 11-10-2018 IPR023214 HAD superfamily AFK25_04290 f7ec46f20c85f84a57e56f5462ed5869 223 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 65 192 1.4E-19 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFK25_04290 f7ec46f20c85f84a57e56f5462ed5869 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 136 152 5.4E-7 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFK25_04290 f7ec46f20c85f84a57e56f5462ed5869 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 154 174 5.4E-7 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFK25_04290 f7ec46f20c85f84a57e56f5462ed5869 223 PRINTS PR00413 Haloacid dehalogenase/epoxide hydrolase family signature 5 16 5.4E-7 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFK25_04290 f7ec46f20c85f84a57e56f5462ed5869 223 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 68 168 4.0E-7 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFK25_04290 f7ec46f20c85f84a57e56f5462ed5869 223 Gene3D G3DSA:1.10.150.240 18 96 5.3E-75 T 11-10-2018 IPR023198 Phosphoglycolate phosphatase-like, domain 2 AFK25_04290 f7ec46f20c85f84a57e56f5462ed5869 223 TIGRFAM TIGR02009 PGMB-YQAB-SF: beta-phosphoglucomutase family hydrolase 6 192 1.5E-67 T 11-10-2018 IPR010976 Beta-phosphoglucomutase hydrolase AFK25_08365 c52728b921fd6aebca8d6ab4d690628e 466 Pfam PF00875 DNA photolyase 4 160 7.3E-35 T 11-10-2018 IPR006050 DNA photolyase, N-terminal Reactome: R-HSA-400253 AFK25_08365 c52728b921fd6aebca8d6ab4d690628e 466 SUPERFAMILY SSF52425 4 173 3.79E-40 T 11-10-2018 IPR036155 Cryptochrome/photolyase, N-terminal domain superfamily Reactome: R-HSA-400253 AFK25_08365 c52728b921fd6aebca8d6ab4d690628e 466 Gene3D G3DSA:1.25.40.80 130 285 1.8E-67 T 11-10-2018 AFK25_08365 c52728b921fd6aebca8d6ab4d690628e 466 SUPERFAMILY SSF48173 199 461 1.44E-103 T 11-10-2018 IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamily Reactome: R-HSA-400253 AFK25_08365 c52728b921fd6aebca8d6ab4d690628e 466 PRINTS PR00147 DNA photolyase signature 380 394 1.0E-27 T 11-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 AFK25_08365 c52728b921fd6aebca8d6ab4d690628e 466 PRINTS PR00147 DNA photolyase signature 141 157 1.0E-27 T 11-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 AFK25_08365 c52728b921fd6aebca8d6ab4d690628e 466 PRINTS PR00147 DNA photolyase signature 341 359 1.0E-27 T 11-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 AFK25_08365 c52728b921fd6aebca8d6ab4d690628e 466 PRINTS PR00147 DNA photolyase signature 321 337 1.0E-27 T 11-10-2018 IPR002081 Cryptochrome/DNA photolyase class 1 AFK25_08365 c52728b921fd6aebca8d6ab4d690628e 466 Gene3D G3DSA:1.10.579.10 291 465 5.7E-78 T 11-10-2018 AFK25_08365 c52728b921fd6aebca8d6ab4d690628e 466 Gene3D G3DSA:3.40.50.620 5 204 1.8E-67 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_08365 c52728b921fd6aebca8d6ab4d690628e 466 Pfam PF03441 FAD binding domain of DNA photolyase 272 461 6.6E-81 T 11-10-2018 IPR005101 Cryptochrome/DNA photolyase, FAD-binding domain Reactome: R-HSA-400253 AFK25_05955 9128aebbfa4b87f7c6904063701ef07f 409 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 2 400 8.6E-139 T 11-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFK25_05955 9128aebbfa4b87f7c6904063701ef07f 409 Gene3D G3DSA:3.40.1160.10 1 255 1.3E-84 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFK25_05955 9128aebbfa4b87f7c6904063701ef07f 409 Pfam PF13840 ACT domain 334 396 5.1E-21 T 11-10-2018 IPR027795 CASTOR, ACT domain AFK25_05955 9128aebbfa4b87f7c6904063701ef07f 409 Gene3D G3DSA:3.30.2130.10 256 408 1.9E-35 T 11-10-2018 AFK25_05955 9128aebbfa4b87f7c6904063701ef07f 409 SUPERFAMILY SSF55021 258 344 8.39E-15 T 11-10-2018 AFK25_05955 9128aebbfa4b87f7c6904063701ef07f 409 SUPERFAMILY SSF53633 3 246 2.49E-70 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFK25_05955 9128aebbfa4b87f7c6904063701ef07f 409 ProSitePatterns PS00324 Aspartokinase signature. 5 13 - T 11-10-2018 IPR018042 Aspartate kinase, conserved site GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFK25_05955 9128aebbfa4b87f7c6904063701ef07f 409 Pfam PF00696 Amino acid kinase family 2 235 3.5E-48 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AFK25_05955 9128aebbfa4b87f7c6904063701ef07f 409 PIRSF PIRSF000726 61 406 1.1E-91 T 11-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFK25_05955 9128aebbfa4b87f7c6904063701ef07f 409 PIRSF PIRSF000726 1 68 1.4E-9 T 11-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFK25_05955 9128aebbfa4b87f7c6904063701ef07f 409 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 67 399 3.2E-93 T 11-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AFK25_05955 9128aebbfa4b87f7c6904063701ef07f 409 SUPERFAMILY SSF55021 332 402 2.52E-15 T 11-10-2018 AFK25_07555 bc61f61886a5f894ad7bc864f2e32c7b 68 ProDom PD058323 YUZF BH2251 3 65 1.0E-16 T 11-10-2018 IPR020139 Protein of unknown function DUF2642 AFK25_07555 bc61f61886a5f894ad7bc864f2e32c7b 68 Pfam PF10842 Protein of unknown function (DUF2642) 4 67 2.3E-32 T 11-10-2018 IPR020139 Protein of unknown function DUF2642 AFK25_03185 8b142a4dddd4be505571ab2f0b53dfb8 430 Gene3D G3DSA:3.40.190.10 71 382 1.4E-117 T 11-10-2018 AFK25_03185 8b142a4dddd4be505571ab2f0b53dfb8 430 Pfam PF13416 Bacterial extracellular solute-binding protein 68 369 2.7E-51 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFK25_03185 8b142a4dddd4be505571ab2f0b53dfb8 430 PRINTS PR00181 Maltose binding protein signature 172 191 1.0E-6 T 11-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 AFK25_03185 8b142a4dddd4be505571ab2f0b53dfb8 430 PRINTS PR00181 Maltose binding protein signature 257 276 1.0E-6 T 11-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 AFK25_03185 8b142a4dddd4be505571ab2f0b53dfb8 430 PRINTS PR00181 Maltose binding protein signature 382 401 1.0E-6 T 11-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 AFK25_03185 8b142a4dddd4be505571ab2f0b53dfb8 430 PRINTS PR00181 Maltose binding protein signature 91 109 1.0E-6 T 11-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 AFK25_03185 8b142a4dddd4be505571ab2f0b53dfb8 430 PRINTS PR00181 Maltose binding protein signature 151 170 1.0E-6 T 11-10-2018 IPR006060 Maltose/Cyclodextrin ABC transporter, substrate-binding protein GO:0008643|GO:0015144 AFK25_03185 8b142a4dddd4be505571ab2f0b53dfb8 430 Gene3D G3DSA:3.40.190.10 160 415 1.4E-117 T 11-10-2018 AFK25_03185 8b142a4dddd4be505571ab2f0b53dfb8 430 SUPERFAMILY SSF53850 55 419 1.8E-93 T 11-10-2018 AFK25_11660 02fefbbe4c31f043a5b42d6e0609f130 417 Pfam PF00390 Malic enzyme, N-terminal domain 15 148 2.0E-28 T 11-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFK25_11660 02fefbbe4c31f043a5b42d6e0609f130 417 Pfam PF03949 Malic enzyme, NAD binding domain 162 383 9.0E-26 T 11-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AFK25_11660 02fefbbe4c31f043a5b42d6e0609f130 417 SMART SM00919 160 384 1.2E-133 T 11-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AFK25_11660 02fefbbe4c31f043a5b42d6e0609f130 417 SUPERFAMILY SSF51735 160 406 1.7E-83 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_11660 02fefbbe4c31f043a5b42d6e0609f130 417 SMART SM01274 15 148 3.3E-83 T 11-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFK25_11660 02fefbbe4c31f043a5b42d6e0609f130 417 PIRSF PIRSF000106 36 407 8.8E-87 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 AFK25_11660 02fefbbe4c31f043a5b42d6e0609f130 417 SUPERFAMILY SSF53223 6 158 2.23E-56 T 11-10-2018 AFK25_11660 02fefbbe4c31f043a5b42d6e0609f130 417 ProSitePatterns PS00331 Malic enzymes signature. 156 172 - T 11-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 AFK25_11660 02fefbbe4c31f043a5b42d6e0609f130 417 Gene3D G3DSA:3.40.50.10380 2 157 1.1E-74 T 11-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 AFK25_11660 02fefbbe4c31f043a5b42d6e0609f130 417 Gene3D G3DSA:3.40.50.720 158 415 3.4E-88 T 11-10-2018 AFK25_00230 b8f34c9a04df6b5919abb0f1c615b3ce 190 SUPERFAMILY SSF110455 5 120 6.28E-37 T 11-10-2018 AFK25_00230 b8f34c9a04df6b5919abb0f1c615b3ce 190 Pfam PF13331 Domain of unknown function (DUF4093) 97 180 5.9E-28 T 11-10-2018 IPR025156 Ribonuclease M5, C-terminal domain AFK25_00230 b8f34c9a04df6b5919abb0f1c615b3ce 190 Hamap MF_01469 Ribonuclease M5 [rnmV]. 7 182 33.2 T 11-10-2018 IPR004466 Ribonuclease M5 GO:0043822 AFK25_00230 b8f34c9a04df6b5919abb0f1c615b3ce 190 TIGRFAM TIGR00334 5S_RNA_mat_M5: ribonuclease M5 6 180 1.8E-61 T 11-10-2018 IPR004466 Ribonuclease M5 GO:0043822 AFK25_00230 b8f34c9a04df6b5919abb0f1c615b3ce 190 Pfam PF13662 Toprim domain 8 76 3.7E-9 T 11-10-2018 IPR006171 TOPRIM domain AFK25_00230 b8f34c9a04df6b5919abb0f1c615b3ce 190 SMART SM00493 8 81 1.8E-10 T 11-10-2018 IPR006171 TOPRIM domain AFK25_00230 b8f34c9a04df6b5919abb0f1c615b3ce 190 Gene3D G3DSA:3.40.1360.20 4 124 1.1E-26 T 11-10-2018 AFK25_14000 0fc37167896d31611323612d6e16dcde 207 Pfam PF00440 Bacterial regulatory proteins, tetR family 24 66 4.3E-12 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_14000 0fc37167896d31611323612d6e16dcde 207 Gene3D G3DSA:1.10.357.10 62 206 2.7E-19 T 11-10-2018 AFK25_14000 0fc37167896d31611323612d6e16dcde 207 Gene3D G3DSA:1.10.10.60 14 59 2.2E-15 T 11-10-2018 AFK25_14000 0fc37167896d31611323612d6e16dcde 207 SUPERFAMILY SSF46689 17 86 6.98E-16 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_14000 0fc37167896d31611323612d6e16dcde 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 23 36 2.2E-6 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_14000 0fc37167896d31611323612d6e16dcde 207 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 44 67 2.2E-6 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_14000 0fc37167896d31611323612d6e16dcde 207 SUPERFAMILY SSF48498 93 206 9.34E-11 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFK25_05705 c759103367fe659ab9de90713dd2d15d 270 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 11-10-2018 IPR019776 Flagellar basal body rod protein, conserved site AFK25_05705 c759103367fe659ab9de90713dd2d15d 270 SUPERFAMILY SSF117143 92 230 5.89E-36 T 11-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like AFK25_05705 c759103367fe659ab9de90713dd2d15d 270 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 191 268 4.5E-24 T 11-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain AFK25_05705 c759103367fe659ab9de90713dd2d15d 270 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 155 251 9.4E-31 T 11-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G AFK25_05705 c759103367fe659ab9de90713dd2d15d 270 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 3 147 5.4E-42 T 11-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G AFK25_05705 c759103367fe659ab9de90713dd2d15d 270 Pfam PF00460 Flagella basal body rod protein 5 35 4.4E-12 T 11-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 AFK25_04585 0a326005a53ca7d256baadb36bc04b66 430 SMART SM00283 190 430 1.4E-33 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_04585 0a326005a53ca7d256baadb36bc04b66 430 Pfam PF11563 Protoglobin 29 182 1.5E-42 T 11-10-2018 AFK25_04585 0a326005a53ca7d256baadb36bc04b66 430 Gene3D G3DSA:1.10.287.950 221 430 1.2E-46 T 11-10-2018 AFK25_04585 0a326005a53ca7d256baadb36bc04b66 430 SUPERFAMILY SSF58104 197 428 3.4E-51 T 11-10-2018 AFK25_04585 0a326005a53ca7d256baadb36bc04b66 430 SUPERFAMILY SSF46458 23 174 2.16E-37 T 11-10-2018 IPR009050 Globin-like superfamily AFK25_04585 0a326005a53ca7d256baadb36bc04b66 430 Gene3D G3DSA:1.10.490.10 22 175 1.6E-42 T 11-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 AFK25_04585 0a326005a53ca7d256baadb36bc04b66 430 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 236 424 4.5E-34 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_10800 2b1747b8834fe622f55b75ab88577c99 507 Pfam PF01943 Polysaccharide biosynthesis protein 4 305 2.3E-55 T 11-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 AFK25_10800 2b1747b8834fe622f55b75ab88577c99 507 TIGRFAM TIGR02900 spore_V_B: stage V sporulation protein B 4 490 1.2E-173 T 11-10-2018 IPR014249 Sporulation stage V protein B AFK25_10800 2b1747b8834fe622f55b75ab88577c99 507 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 358 495 7.3E-16 T 11-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain AFK25_10800 2b1747b8834fe622f55b75ab88577c99 507 PIRSF PIRSF038958 1 507 5.2E-174 T 11-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type AFK25_06790 b35d242400286d60a023af621e499782 608 TIGRFAM TIGR00585 mutl: DNA mismatch repair protein MutL 3 306 1.1E-97 T 11-10-2018 IPR002099 DNA mismatch repair protein family, N-terminal GO:0005524|GO:0006298|GO:0030983 AFK25_06790 b35d242400286d60a023af621e499782 608 SUPERFAMILY SSF55874 3 213 1.31E-51 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_06790 b35d242400286d60a023af621e499782 608 ProSitePatterns PS00058 DNA mismatch repair proteins mutL / hexB / PMS1 signature. 94 100 - T 11-10-2018 IPR014762 DNA mismatch repair, conserved site AFK25_06790 b35d242400286d60a023af621e499782 608 Hamap MF_00149 DNA mismatch repair protein MutL [mutL]. 2 604 27.54 T 11-10-2018 IPR020667 DNA mismatch repair protein, MutL GO:0006298 AFK25_06790 b35d242400286d60a023af621e499782 608 SUPERFAMILY SSF54211 189 326 6.45E-38 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFK25_06790 b35d242400286d60a023af621e499782 608 SMART SM01340 208 326 1.4E-55 T 11-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 AFK25_06790 b35d242400286d60a023af621e499782 608 Pfam PF01119 DNA mismatch repair protein, C-terminal domain 209 325 8.3E-36 T 11-10-2018 IPR013507 DNA mismatch repair protein, S5 domain 2-like GO:0005524|GO:0006298|GO:0030983 AFK25_06790 b35d242400286d60a023af621e499782 608 SMART SM00853 422 564 1.3E-52 T 11-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 AFK25_06790 b35d242400286d60a023af621e499782 608 Gene3D G3DSA:3.30.1370.100 464 557 1.8E-64 T 11-10-2018 AFK25_06790 b35d242400286d60a023af621e499782 608 Gene3D G3DSA:2.30.42.20 423 606 1.8E-64 T 11-10-2018 AFK25_06790 b35d242400286d60a023af621e499782 608 Pfam PF13589 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 25 97 1.2E-8 T 11-10-2018 AFK25_06790 b35d242400286d60a023af621e499782 608 Gene3D G3DSA:3.30.230.10 213 325 5.4E-33 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFK25_06790 b35d242400286d60a023af621e499782 608 Gene3D G3DSA:3.30.565.10 1 212 1.5E-60 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_06790 b35d242400286d60a023af621e499782 608 Pfam PF08676 MutL C terminal dimerisation domain 422 562 1.1E-46 T 11-10-2018 IPR014790 MutL, C-terminal, dimerisation GO:0005524|GO:0006298 AFK25_06790 b35d242400286d60a023af621e499782 608 SUPERFAMILY SSF118116 418 606 2.22E-55 T 11-10-2018 IPR037198 MutL, C-terminal domain superfamily AFK25_13920 f696968b486d02d635496efb727eb438 347 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 20 213 3.3E-65 T 11-10-2018 IPR006070 YrdC-like domain GO:0003725 AFK25_13920 f696968b486d02d635496efb727eb438 347 Pfam PF01300 Telomere recombination 27 202 7.7E-58 T 11-10-2018 IPR006070 YrdC-like domain GO:0003725 AFK25_13920 f696968b486d02d635496efb727eb438 347 Pfam PF03481 Putative GTP-binding controlling metal-binding 204 340 2.0E-28 T 11-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain AFK25_13920 f696968b486d02d635496efb727eb438 347 Gene3D G3DSA:3.40.50.11030 221 347 6.5E-40 T 11-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily AFK25_13920 f696968b486d02d635496efb727eb438 347 Gene3D G3DSA:3.90.870.10 4 217 3.5E-85 T 11-10-2018 AFK25_13920 f696968b486d02d635496efb727eb438 347 SUPERFAMILY SSF55821 20 214 9.46E-69 T 11-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AFK25_13920 f696968b486d02d635496efb727eb438 347 PIRSF PIRSF004930 2 346 8.9E-132 T 11-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 AFK25_00980 ac5a89aee683ac0a581c2daed760c484 347 SUPERFAMILY SSF51905 1 316 4.32E-39 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_00980 ac5a89aee683ac0a581c2daed760c484 347 Gene3D G3DSA:3.50.50.60 125 246 5.3E-83 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_00980 ac5a89aee683ac0a581c2daed760c484 347 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 6.4E-18 T 11-10-2018 AFK25_00980 ac5a89aee683ac0a581c2daed760c484 347 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 153 171 6.4E-18 T 11-10-2018 AFK25_00980 ac5a89aee683ac0a581c2daed760c484 347 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 268 290 6.4E-18 T 11-10-2018 AFK25_00980 ac5a89aee683ac0a581c2daed760c484 347 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 6.4E-18 T 11-10-2018 AFK25_00980 ac5a89aee683ac0a581c2daed760c484 347 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 239 255 6.4E-18 T 11-10-2018 AFK25_00980 ac5a89aee683ac0a581c2daed760c484 347 Hamap MF_01685 Ferredoxin--NADP reductase. 4 331 36.821 T 11-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 AFK25_00980 ac5a89aee683ac0a581c2daed760c484 347 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 303 2.7E-27 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFK25_00980 ac5a89aee683ac0a581c2daed760c484 347 Gene3D G3DSA:3.50.50.60 6 310 5.3E-83 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_00980 ac5a89aee683ac0a581c2daed760c484 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 110 118 3.8E-18 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_00980 ac5a89aee683ac0a581c2daed760c484 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 62 72 3.8E-18 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_00980 ac5a89aee683ac0a581c2daed760c484 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 149 173 3.8E-18 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_00980 ac5a89aee683ac0a581c2daed760c484 347 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 6 28 3.8E-18 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_00715 7c097a5ce21b53b791184ca422bcd6ea 248 ProSitePatterns PS00680 Methionine aminopeptidase subfamily 1 signature. 165 183 - T 11-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFK25_00715 7c097a5ce21b53b791184ca422bcd6ea 248 SUPERFAMILY SSF55920 1 246 6.02E-95 T 11-10-2018 IPR036005 Creatinase/aminopeptidase-like AFK25_00715 7c097a5ce21b53b791184ca422bcd6ea 248 Gene3D G3DSA:3.90.230.10 1 248 1.0E-111 T 11-10-2018 AFK25_00715 7c097a5ce21b53b791184ca422bcd6ea 248 Hamap MF_01974 Methionine aminopeptidase [map]. 2 248 43.928 T 11-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFK25_00715 7c097a5ce21b53b791184ca422bcd6ea 248 Pfam PF00557 Metallopeptidase family M24 12 239 4.4E-58 T 11-10-2018 IPR000994 Peptidase M24 AFK25_00715 7c097a5ce21b53b791184ca422bcd6ea 248 TIGRFAM TIGR00500 met_pdase_I: methionine aminopeptidase, type I 2 247 1.4E-104 T 11-10-2018 IPR002467 Peptidase M24A, methionine aminopeptidase, subfamily 1 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFK25_00715 7c097a5ce21b53b791184ca422bcd6ea 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 67 80 1.1E-23 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFK25_00715 7c097a5ce21b53b791184ca422bcd6ea 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 159 171 1.1E-23 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFK25_00715 7c097a5ce21b53b791184ca422bcd6ea 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 190 202 1.1E-23 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFK25_00715 7c097a5ce21b53b791184ca422bcd6ea 248 PRINTS PR00599 Methionine aminopeptidase-1 signature 89 105 1.1E-23 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFK25_13370 ebeb2b043668d210202c54e5208c0267 552 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 34 57 6.8E-5 T 11-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFK25_13370 ebeb2b043668d210202c54e5208c0267 552 PRINTS PR01490 Gram-negative bacterial RTX secretion protein D signature 76 96 6.8E-5 T 11-10-2018 IPR003997 RTX secretion protein D, Gram-negative bacteria GO:0009306|GO:0016020 AFK25_13370 ebeb2b043668d210202c54e5208c0267 552 Pfam PF13533 Biotin-lipoyl like 65 112 6.1E-10 T 11-10-2018 IPR039562 Membrane fusion protein, biotin-lipoyl like domain AFK25_13370 ebeb2b043668d210202c54e5208c0267 552 SUPERFAMILY SSF111369 65 129 7.98E-5 T 11-10-2018 AFK25_13370 ebeb2b043668d210202c54e5208c0267 552 Gene3D G3DSA:2.40.50.100 67 126 5.8E-5 T 11-10-2018 AFK25_13370 ebeb2b043668d210202c54e5208c0267 552 Gene3D G3DSA:2.40.30.170 417 541 3.0E-11 T 11-10-2018 AFK25_13370 ebeb2b043668d210202c54e5208c0267 552 Pfam PF13437 HlyD family secretion protein 408 525 1.7E-15 T 11-10-2018 AFK25_06905 1eb2eac1777b9f6c43228072017be4f8 155 PIRSF PIRSF021441 1 155 1.3E-67 T 11-10-2018 IPR031306 CcdC protein AFK25_06905 1eb2eac1777b9f6c43228072017be4f8 155 Pfam PF07301 Protein of unknown function (DUF1453) 4 147 1.7E-60 T 11-10-2018 IPR009916 Protein of unknown function DUF1453 AFK25_12780 087c177a6d32140f861e797eb96a650a 115 SUPERFAMILY SSF110455 5 113 1.78E-34 T 11-10-2018 AFK25_12780 087c177a6d32140f861e797eb96a650a 115 Gene3D G3DSA:3.40.1360.20 3 115 2.9E-44 T 11-10-2018 AFK25_12780 087c177a6d32140f861e797eb96a650a 115 SMART SM00493 7 81 1.2E-8 T 11-10-2018 IPR006171 TOPRIM domain AFK25_12780 087c177a6d32140f861e797eb96a650a 115 Pfam PF01751 Toprim domain 9 77 1.3E-5 T 11-10-2018 IPR006171 TOPRIM domain AFK25_05775 c929ee4028db4112981ac813acda9bde 356 Gene3D G3DSA:3.40.50.2300 2 142 9.7E-37 T 11-10-2018 AFK25_05775 c929ee4028db4112981ac813acda9bde 356 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 4 355 39.72 T 11-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AFK25_05775 c929ee4028db4112981ac813acda9bde 356 PIRSF PIRSF000876 1 356 1.5E-140 T 11-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AFK25_05775 c929ee4028db4112981ac813acda9bde 356 Gene3D G3DSA:3.40.50.180 162 354 4.3E-69 T 11-10-2018 IPR035909 Methylesterase CheB, C-terminal AFK25_05775 c929ee4028db4112981ac813acda9bde 356 Pfam PF00072 Response regulator receiver domain 6 111 1.7E-25 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_05775 c929ee4028db4112981ac813acda9bde 356 SMART SM00448 4 123 4.2E-29 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_05775 c929ee4028db4112981ac813acda9bde 356 SUPERFAMILY SSF52738 167 354 1.26E-62 T 11-10-2018 IPR035909 Methylesterase CheB, C-terminal AFK25_05775 c929ee4028db4112981ac813acda9bde 356 SUPERFAMILY SSF52172 2 111 1.17E-31 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_05775 c929ee4028db4112981ac813acda9bde 356 Pfam PF01339 CheB methylesterase 170 348 1.1E-58 T 11-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AFK25_01995 1ce33e93697c6014be253a95c943738e 147 Gene3D G3DSA:1.10.10.10 4 90 4.2E-34 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_01995 1ce33e93697c6014be253a95c943738e 147 SUPERFAMILY SSF46785 11 141 1.7E-42 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_01995 1ce33e93697c6014be253a95c943738e 147 Pfam PF01475 Ferric uptake regulator family 18 136 2.0E-41 T 11-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 AFK25_01995 1ce33e93697c6014be253a95c943738e 147 Gene3D G3DSA:3.30.1490.190 91 147 7.3E-24 T 11-10-2018 AFK25_08675 8ebc9be9075f30307b0d3c8fa2d200a8 550 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 20 32 3.7E-31 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFK25_08675 8ebc9be9075f30307b0d3c8fa2d200a8 550 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 33 43 3.7E-31 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFK25_08675 8ebc9be9075f30307b0d3c8fa2d200a8 550 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 94 106 3.7E-31 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFK25_08675 8ebc9be9075f30307b0d3c8fa2d200a8 550 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 367 379 3.7E-31 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFK25_08675 8ebc9be9075f30307b0d3c8fa2d200a8 550 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 337 343 3.7E-31 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFK25_08675 8ebc9be9075f30307b0d3c8fa2d200a8 550 PRINTS PR01001 FAD-dependent glycerol-3-phosphate dehydrogenase family signature 49 61 3.7E-31 T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFK25_08675 8ebc9be9075f30307b0d3c8fa2d200a8 550 Pfam PF16901 C-terminal domain of alpha-glycerophosphate oxidase 400 527 3.1E-23 T 11-10-2018 IPR031656 Alpha-glycerophosphate oxidase, C-terminal KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFK25_08675 8ebc9be9075f30307b0d3c8fa2d200a8 550 Gene3D G3DSA:3.50.50.60 18 380 2.2E-136 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_08675 8ebc9be9075f30307b0d3c8fa2d200a8 550 SUPERFAMILY SSF54373 249 343 3.01E-13 T 11-10-2018 AFK25_08675 8ebc9be9075f30307b0d3c8fa2d200a8 550 Gene3D G3DSA:3.30.9.10 102 344 2.2E-136 T 11-10-2018 AFK25_08675 8ebc9be9075f30307b0d3c8fa2d200a8 550 ProSitePatterns PS00977 FAD-dependent glycerol-3-phosphate dehydrogenase signature 1. 25 42 - T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFK25_08675 8ebc9be9075f30307b0d3c8fa2d200a8 550 Gene3D G3DSA:1.10.8.870 417 546 2.5E-41 T 11-10-2018 IPR038299 Alpha-glycerophosphate oxidase, C-terminal domain superfamily KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFK25_08675 8ebc9be9075f30307b0d3c8fa2d200a8 550 SUPERFAMILY SSF51905 15 395 3.39E-36 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_08675 8ebc9be9075f30307b0d3c8fa2d200a8 550 Pfam PF01266 FAD dependent oxidoreductase 21 351 7.0E-57 T 11-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFK25_08675 8ebc9be9075f30307b0d3c8fa2d200a8 550 ProSitePatterns PS00978 FAD-dependent glycerol-3-phosphate dehydrogenase signature 2. 372 382 - T 11-10-2018 IPR000447 FAD-dependent glycerol-3-phosphate dehydrogenase GO:0004368|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.5.3|MetaCyc: PWY-4261|MetaCyc: PWY-6118|MetaCyc: PWY-6952|Reactome: R-HSA-1483166|Reactome: R-HSA-163560 AFK25_10840 1a814ed116920ec754c48c0d33fca22d 197 Gene3D G3DSA:2.40.50.140 1 64 2.6E-17 T 11-10-2018 AFK25_10840 1a814ed116920ec754c48c0d33fca22d 197 SUPERFAMILY SSF47781 64 135 1.72E-20 T 11-10-2018 IPR010994 RuvA domain 2-like AFK25_10840 1a814ed116920ec754c48c0d33fca22d 197 SMART SM00278 72 91 0.091 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFK25_10840 1a814ed116920ec754c48c0d33fca22d 197 SMART SM00278 107 126 1.3 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFK25_10840 1a814ed116920ec754c48c0d33fca22d 197 Gene3D G3DSA:1.10.150.20 66 140 7.8E-25 T 11-10-2018 AFK25_10840 1a814ed116920ec754c48c0d33fca22d 197 TIGRFAM TIGR00084 ruvA: Holliday junction DNA helicase RuvA 1 196 4.1E-62 T 11-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 AFK25_10840 1a814ed116920ec754c48c0d33fca22d 197 Pfam PF07499 RuvA, C-terminal domain 152 195 3.1E-11 T 11-10-2018 IPR011114 Holliday junction DNA helicase RuvA, C-terminal GO:0005524|GO:0006281|GO:0006310|GO:0009378|GO:0009379 AFK25_10840 1a814ed116920ec754c48c0d33fca22d 197 Hamap MF_00031 Holliday junction ATP-dependent DNA helicase RuvA [ruvA]. 1 196 29.872 T 11-10-2018 IPR000085 Bacterial DNA recombination protein RuvA GO:0003678|GO:0006281|GO:0006310 AFK25_10840 1a814ed116920ec754c48c0d33fca22d 197 Pfam PF14520 Helix-hairpin-helix domain 71 128 7.0E-16 T 11-10-2018 AFK25_10840 1a814ed116920ec754c48c0d33fca22d 197 SUPERFAMILY SSF50249 1 62 1.94E-16 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_10840 1a814ed116920ec754c48c0d33fca22d 197 Gene3D G3DSA:1.10.8.10 149 195 9.8E-8 T 11-10-2018 AFK25_10840 1a814ed116920ec754c48c0d33fca22d 197 SUPERFAMILY SSF46929 151 195 4.58E-10 T 11-10-2018 IPR036267 RuvA, C-terminal domain superfamily AFK25_10840 1a814ed116920ec754c48c0d33fca22d 197 Pfam PF01330 RuvA N terminal domain 2 61 3.2E-18 T 11-10-2018 IPR013849 DNA helicase, Holliday junction RuvA type, domain I, bacterial GO:0005524|GO:0006281|GO:0006310|GO:0009378 AFK25_13080 53f36353b1dda042593a707f48cd9d4a 137 SUPERFAMILY SSF46955 2 52 2.62E-9 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily AFK25_13080 53f36353b1dda042593a707f48cd9d4a 137 Pfam PF13411 MerR HTH family regulatory protein 5 54 3.6E-11 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_13080 53f36353b1dda042593a707f48cd9d4a 137 Hamap MF_01170 Chromosome-anchoring protein RacA [racA]. 3 135 19.941 T 11-10-2018 IPR023522 Chromosome-anchoring protein RacA AFK25_13080 53f36353b1dda042593a707f48cd9d4a 137 Gene3D G3DSA:1.10.1660.10 1 82 4.0E-20 T 11-10-2018 AFK25_05195 a1d30dc0113e04c95afe918b21b04a5a 724 SUPERFAMILY SSF54184 589 645 4.45E-12 T 11-10-2018 AFK25_05195 a1d30dc0113e04c95afe918b21b04a5a 724 Gene3D G3DSA:3.90.1310.10 59 199 1.4E-52 T 11-10-2018 AFK25_05195 a1d30dc0113e04c95afe918b21b04a5a 724 Pfam PF03717 Penicillin-binding Protein dimerisation domain 58 211 1.6E-23 T 11-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 AFK25_05195 a1d30dc0113e04c95afe918b21b04a5a 724 Pfam PF03793 PASTA domain 650 703 1.1E-8 T 11-10-2018 IPR005543 PASTA domain AFK25_05195 a1d30dc0113e04c95afe918b21b04a5a 724 Pfam PF03793 PASTA domain 591 636 7.6E-7 T 11-10-2018 IPR005543 PASTA domain AFK25_05195 a1d30dc0113e04c95afe918b21b04a5a 724 SUPERFAMILY SSF54184 649 701 4.45E-13 T 11-10-2018 AFK25_05195 a1d30dc0113e04c95afe918b21b04a5a 724 Gene3D G3DSA:2.20.70.70 55 219 1.4E-52 T 11-10-2018 AFK25_05195 a1d30dc0113e04c95afe918b21b04a5a 724 SUPERFAMILY SSF56601 183 585 8.98E-100 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFK25_05195 a1d30dc0113e04c95afe918b21b04a5a 724 SUPERFAMILY SSF56519 53 232 1.11E-43 T 11-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 AFK25_05195 a1d30dc0113e04c95afe918b21b04a5a 724 Gene3D G3DSA:3.40.710.10 226 579 5.3E-103 T 11-10-2018 AFK25_05195 a1d30dc0113e04c95afe918b21b04a5a 724 SMART SM00740 648 703 9.6E-6 T 11-10-2018 IPR005543 PASTA domain AFK25_05195 a1d30dc0113e04c95afe918b21b04a5a 724 SMART SM00740 586 646 6.2E-11 T 11-10-2018 IPR005543 PASTA domain AFK25_05195 a1d30dc0113e04c95afe918b21b04a5a 724 Pfam PF00905 Penicillin binding protein transpeptidase domain 258 567 1.4E-86 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFK25_05195 a1d30dc0113e04c95afe918b21b04a5a 724 Gene3D G3DSA:3.30.70.2110 78 154 1.4E-52 T 11-10-2018 AFK25_05900 8b25c93e6bf2a0e92844945a8558b90e 119 ProDom PD007327 FACTOR A RIBOSOME-BINDING PROCESSING RRNA 3D-STRUCTURE RIBOSOMAL-BINDING PRECURSOR A RBFA 7 94 3.0E-38 T 11-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 AFK25_05900 8b25c93e6bf2a0e92844945a8558b90e 119 Gene3D G3DSA:3.30.300.20 1 116 3.5E-41 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta AFK25_05900 8b25c93e6bf2a0e92844945a8558b90e 119 ProSitePatterns PS01319 Ribosome-binding factor A signature. 73 94 - T 11-10-2018 IPR020053 Ribosome-binding factor A, conserved site GO:0006364 AFK25_05900 8b25c93e6bf2a0e92844945a8558b90e 119 TIGRFAM TIGR00082 rbfA: ribosome-binding factor A 4 112 1.4E-40 T 11-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 AFK25_05900 8b25c93e6bf2a0e92844945a8558b90e 119 SUPERFAMILY SSF89919 2 110 2.35E-37 T 11-10-2018 IPR023799 Ribosome-binding factor A domain superfamily AFK25_05900 8b25c93e6bf2a0e92844945a8558b90e 119 Hamap MF_00003 Ribosome-binding factor A [rbfA]. 3 107 28.274 T 11-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 AFK25_05900 8b25c93e6bf2a0e92844945a8558b90e 119 Pfam PF02033 Ribosome-binding factor A 4 107 3.3E-35 T 11-10-2018 IPR000238 Ribosome-binding factor A GO:0006364 AFK25_07520 75ce12f19cc27d3f713b3063b8e093c1 299 SUPERFAMILY SSF52540 2 227 2.72E-51 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_07520 75ce12f19cc27d3f713b3063b8e093c1 299 SMART SM00382 26 281 9.7E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_07520 75ce12f19cc27d3f713b3063b8e093c1 299 Gene3D G3DSA:3.40.50.300 1 227 7.5E-51 T 11-10-2018 AFK25_07520 75ce12f19cc27d3f713b3063b8e093c1 299 Pfam PF00005 ABC transporter 18 154 1.1E-25 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_07235 6d5b8bb17050bff76c4d3f9b70ca55d1 554 Pfam PF00128 Alpha amylase, catalytic domain 27 370 1.1E-130 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFK25_07235 6d5b8bb17050bff76c4d3f9b70ca55d1 554 Gene3D G3DSA:3.90.400.10 109 164 4.6E-29 T 11-10-2018 AFK25_07235 6d5b8bb17050bff76c4d3f9b70ca55d1 554 Gene3D G3DSA:3.20.20.80 1 108 4.9E-51 T 11-10-2018 AFK25_07235 6d5b8bb17050bff76c4d3f9b70ca55d1 554 Gene3D G3DSA:3.20.20.80 165 473 1.0E-127 T 11-10-2018 AFK25_07235 6d5b8bb17050bff76c4d3f9b70ca55d1 554 Gene3D G3DSA:2.60.40.1180 474 554 2.9E-25 T 11-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFK25_07235 6d5b8bb17050bff76c4d3f9b70ca55d1 554 SUPERFAMILY SSF51445 3 470 5.99E-161 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily AFK25_07235 6d5b8bb17050bff76c4d3f9b70ca55d1 554 Pfam PF16657 Maltogenic Amylase, C-terminal domain 473 517 8.9E-7 T 11-10-2018 IPR032091 Maltogenic Amylase, C-terminal AFK25_07235 6d5b8bb17050bff76c4d3f9b70ca55d1 554 TIGRFAM TIGR02403 trehalose_treC: alpha,alpha-phosphotrehalase 4 550 9.5E-272 T 11-10-2018 IPR012769 Trehalose-6-phosphate hydrolase GO:0005737|GO:0005993|GO:0008788 KEGG: 00500+3.2.1.93 AFK25_07235 6d5b8bb17050bff76c4d3f9b70ca55d1 554 SMART SM00642 12 412 3.2E-170 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFK25_07235 6d5b8bb17050bff76c4d3f9b70ca55d1 554 SUPERFAMILY SSF51011 473 552 1.73E-19 T 11-10-2018 AFK25_01220 eb9230db649154782aac53c88f714eae 631 Pfam PF16326 ABC transporter C-terminal domain 563 630 1.2E-13 T 11-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 AFK25_01220 eb9230db649154782aac53c88f714eae 631 ProSitePatterns PS00211 ABC transporters family signature. 442 456 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_01220 eb9230db649154782aac53c88f714eae 631 Gene3D G3DSA:3.40.50.300 1 284 9.5E-74 T 11-10-2018 AFK25_01220 eb9230db649154782aac53c88f714eae 631 ProSitePatterns PS00211 ABC transporters family signature. 162 176 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_01220 eb9230db649154782aac53c88f714eae 631 Pfam PF12848 ABC transporter 229 315 1.6E-27 T 11-10-2018 IPR032781 ABC-transporter extension domain AFK25_01220 eb9230db649154782aac53c88f714eae 631 SUPERFAMILY SSF52540 4 242 3.58E-49 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_01220 eb9230db649154782aac53c88f714eae 631 SUPERFAMILY SSF52540 311 526 2.0E-44 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_01220 eb9230db649154782aac53c88f714eae 631 Pfam PF00005 ABC transporter 341 470 5.0E-24 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_01220 eb9230db649154782aac53c88f714eae 631 SMART SM00382 349 522 1.3E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_01220 eb9230db649154782aac53c88f714eae 631 SMART SM00382 28 321 3.1E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_01220 eb9230db649154782aac53c88f714eae 631 Gene3D G3DSA:3.40.50.300 287 551 3.2E-58 T 11-10-2018 AFK25_01220 eb9230db649154782aac53c88f714eae 631 Gene3D G3DSA:1.10.287.380 553 631 1.1E-7 T 11-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 AFK25_01220 eb9230db649154782aac53c88f714eae 631 Pfam PF00005 ABC transporter 19 190 2.7E-26 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 209 794 1.1E-195 T 11-10-2018 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 SUPERFAMILY SSF55008 3 70 1.11E-19 T 11-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 267 770 1.6E-97 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 ProSitePatterns PS01047 Heavy-metal-associated domain. 11 39 - T 11-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 ProSitePatterns PS01047 Heavy-metal-associated domain. 78 107 - T 11-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 Pfam PF00122 E1-E2 ATPase 295 476 5.7E-57 T 11-10-2018 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 Gene3D G3DSA:2.70.150.20 287 399 3.4E-43 T 11-10-2018 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 Gene3D G3DSA:3.40.1110.10 507 623 9.6E-98 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 227 793 5.4E-206 T 11-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 SUPERFAMILY SSF81665 262 762 6.8E-12 T 11-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 Pfam PF00403 Heavy-metal-associated domain 8 67 1.1E-15 T 11-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 Pfam PF00403 Heavy-metal-associated domain 75 136 1.8E-19 T 11-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 616 627 3.2E-27 T 11-10-2018 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 344 358 3.2E-27 T 11-10-2018 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 638 648 3.2E-27 T 11-10-2018 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 714 726 3.2E-27 T 11-10-2018 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 496 510 3.2E-27 T 11-10-2018 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 691 710 3.2E-27 T 11-10-2018 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 Gene3D G3DSA:3.40.50.1000 477 743 9.6E-98 T 11-10-2018 IPR023214 HAD superfamily AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 73 136 4.4E-13 T 11-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 7 69 1.6E-11 T 11-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 498 504 - T 11-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 SUPERFAMILY SSF81653 298 394 2.75E-29 T 11-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 PRINTS PR00942 Copper-transporting ATPase 1 signature 6 31 1.8E-11 T 11-10-2018 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 PRINTS PR00942 Copper-transporting ATPase 1 signature 190 210 1.8E-11 T 11-10-2018 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 PRINTS PR00942 Copper-transporting ATPase 1 signature 210 235 1.8E-11 T 11-10-2018 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 SUPERFAMILY SSF55008 71 140 3.4E-22 T 11-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 Gene3D G3DSA:3.30.70.100 1 71 7.6E-22 T 11-10-2018 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 SUPERFAMILY SSF56784 495 791 7.7E-64 T 11-10-2018 IPR036412 HAD-like superfamily AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 Pfam PF00702 haloacid dehalogenase-like hydrolase 492 705 2.4E-49 T 11-10-2018 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 Gene3D G3DSA:3.30.70.100 72 149 7.4E-23 T 11-10-2018 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 PRINTS PR00943 Copper-transporting ATPase signature 264 283 1.4E-18 T 11-10-2018 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 PRINTS PR00943 Copper-transporting ATPase signature 479 494 1.4E-18 T 11-10-2018 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 PRINTS PR00943 Copper-transporting ATPase signature 668 685 1.4E-18 T 11-10-2018 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 PRINTS PR00943 Copper-transporting ATPase signature 417 431 1.4E-18 T 11-10-2018 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 PRINTS PR00943 Copper-transporting ATPase signature 117 137 1.4E-18 T 11-10-2018 AFK25_08395 8b36b28f4cfbb2936d94e0620c0d619b 798 PRINTS PR00943 Copper-transporting ATPase signature 212 231 1.4E-18 T 11-10-2018 AFK25_01405 f9ce46803a3e4340c447d10b2c09eb2d 96 SUPERFAMILY SSF141000 3 94 3.92E-33 T 11-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 AFK25_01405 f9ce46803a3e4340c447d10b2c09eb2d 96 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 4 96 1.4E-33 T 11-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AFK25_01405 f9ce46803a3e4340c447d10b2c09eb2d 96 Gene3D G3DSA:1.10.20.60 1 94 3.9E-32 T 11-10-2018 AFK25_01405 f9ce46803a3e4340c447d10b2c09eb2d 96 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 3 96 26.74 T 11-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AFK25_01405 f9ce46803a3e4340c447d10b2c09eb2d 96 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 20 91 2.0E-23 T 11-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AFK25_01290 70fd752167b70ef916098977e483c28a 382 SUPERFAMILY SSF51246 311 377 2.75E-17 T 11-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFK25_01290 70fd752167b70ef916098977e483c28a 382 Pfam PF03446 NAD binding domain of 6-phosphogluconate dehydrogenase 13 76 1.6E-4 T 11-10-2018 IPR006115 6-phosphogluconate dehydrogenase, NADP-binding GO:0050661 AFK25_01290 70fd752167b70ef916098977e483c28a 382 SUPERFAMILY SSF56059 109 308 2.12E-65 T 11-10-2018 AFK25_01290 70fd752167b70ef916098977e483c28a 382 Hamap MF_01928 N5-carboxyaminoimidazole ribonucleotide synthase [purK]. 13 362 44.214 T 11-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 AFK25_01290 70fd752167b70ef916098977e483c28a 382 Gene3D G3DSA:3.30.470.20 188 377 1.3E-82 T 11-10-2018 AFK25_01290 70fd752167b70ef916098977e483c28a 382 Pfam PF02222 ATP-grasp domain 118 287 3.1E-59 T 11-10-2018 IPR003135 ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type AFK25_01290 70fd752167b70ef916098977e483c28a 382 TIGRFAM TIGR01161 purK: phosphoribosylaminoimidazole carboxylase, ATPase subunit 13 367 1.7E-133 T 11-10-2018 IPR005875 Phosphoribosylaminoimidazole carboxylase, ATPase subunit GO:0004638|GO:0006189 AFK25_01290 70fd752167b70ef916098977e483c28a 382 Gene3D G3DSA:3.40.50.20 1 118 1.9E-49 T 11-10-2018 AFK25_01290 70fd752167b70ef916098977e483c28a 382 Gene3D G3DSA:3.30.1490.20 119 187 2.6E-25 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFK25_01290 70fd752167b70ef916098977e483c28a 382 SUPERFAMILY SSF52440 10 97 1.12E-28 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFK25_12670 6392930321d3082be198bf45b14251c9 91 Gene3D G3DSA:3.50.4.20 1 91 1.3E-42 T 11-10-2018 IPR038141 YutD-like superfamily AFK25_12670 6392930321d3082be198bf45b14251c9 91 PIRSF PIRSF012565 1 91 2.9E-49 T 11-10-2018 IPR009370 Protein of unknown function DUF1027 AFK25_12670 6392930321d3082be198bf45b14251c9 91 Pfam PF06265 Protein of unknown function (DUF1027) 4 87 1.2E-38 T 11-10-2018 IPR009370 Protein of unknown function DUF1027 AFK25_09535 28093db3fc5dea850418ab16e20bb2f1 417 Gene3D G3DSA:3.90.105.10 23 180 8.8E-125 T 11-10-2018 AFK25_09535 28093db3fc5dea850418ab16e20bb2f1 417 Gene3D G3DSA:3.40.980.10 181 334 8.8E-125 T 11-10-2018 IPR036425 MoaB/Mog-like domain superfamily AFK25_09535 28093db3fc5dea850418ab16e20bb2f1 417 SUPERFAMILY SSF53218 183 329 5.37E-40 T 11-10-2018 IPR036425 MoaB/Mog-like domain superfamily AFK25_09535 28093db3fc5dea850418ab16e20bb2f1 417 Pfam PF00994 Probable molybdopterin binding domain 186 323 2.6E-26 T 11-10-2018 IPR001453 MoaB/Mog domain AFK25_09535 28093db3fc5dea850418ab16e20bb2f1 417 Pfam PF03454 MoeA C-terminal region (domain IV) 337 408 1.5E-19 T 11-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFK25_09535 28093db3fc5dea850418ab16e20bb2f1 417 SUPERFAMILY SSF63882 4 182 2.22E-52 T 11-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFK25_09535 28093db3fc5dea850418ab16e20bb2f1 417 Gene3D G3DSA:2.40.340.10 335 403 8.8E-125 T 11-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFK25_09535 28093db3fc5dea850418ab16e20bb2f1 417 SMART SM00852 186 324 3.9E-40 T 11-10-2018 IPR001453 MoaB/Mog domain AFK25_09535 28093db3fc5dea850418ab16e20bb2f1 417 SUPERFAMILY SSF63867 334 410 5.36E-20 T 11-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFK25_09535 28093db3fc5dea850418ab16e20bb2f1 417 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 182 320 3.4E-34 T 11-10-2018 IPR001453 MoaB/Mog domain AFK25_09535 28093db3fc5dea850418ab16e20bb2f1 417 Gene3D G3DSA:2.170.190.11 47 147 8.8E-125 T 11-10-2018 AFK25_09535 28093db3fc5dea850418ab16e20bb2f1 417 Pfam PF03453 MoeA N-terminal region (domain I and II) 6 173 2.2E-41 T 11-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFK25_00235 173be29d6fbdbdacc591ad3fb64290df 295 Pfam PF00398 Ribosomal RNA adenine dimethylase 20 280 1.0E-76 T 11-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm AFK25_00235 173be29d6fbdbdacc591ad3fb64290df 295 SMART SM00650 36 212 2.3E-86 T 11-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 AFK25_00235 173be29d6fbdbdacc591ad3fb64290df 295 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 20 288 55.975 T 11-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 AFK25_00235 173be29d6fbdbdacc591ad3fb64290df 295 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 52 79 - T 11-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 AFK25_00235 173be29d6fbdbdacc591ad3fb64290df 295 SUPERFAMILY SSF53335 16 290 2.37E-76 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_00235 173be29d6fbdbdacc591ad3fb64290df 295 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 20 286 1.9E-86 T 11-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 AFK25_00235 173be29d6fbdbdacc591ad3fb64290df 295 Gene3D G3DSA:1.10.8.100 220 290 8.8E-22 T 11-10-2018 IPR023165 rRNA adenine dimethylase-like Reactome: R-HSA-2151201|Reactome: R-HSA-6793080 AFK25_00235 173be29d6fbdbdacc591ad3fb64290df 295 Gene3D G3DSA:3.40.50.150 2 216 3.9E-74 T 11-10-2018 AFK25_09105 57c77c831217db2647285cdbe6d8fc15 189 SUPERFAMILY SSF47240 1 185 3.07E-70 T 11-10-2018 IPR009078 Ferritin-like superfamily AFK25_09105 57c77c831217db2647285cdbe6d8fc15 189 Pfam PF05067 Manganese containing catalase 1 184 4.6E-77 T 11-10-2018 IPR007760 Manganese catalase AFK25_09105 57c77c831217db2647285cdbe6d8fc15 189 Gene3D G3DSA:1.20.1260.10 1 184 6.2E-66 T 11-10-2018 IPR012347 Ferritin-like AFK25_05640 1d74466abeb60842b975e837053fce06 460 SUPERFAMILY SSF52540 2 458 9.67E-89 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_05640 1d74466abeb60842b975e837053fce06 460 Hamap MF_00249 ATP-dependent protease ATPase subunit HslU [hslU]. 1 460 43.309 T 11-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 AFK25_05640 1d74466abeb60842b975e837053fce06 460 SMART SM01086 352 446 5.7E-26 T 11-10-2018 IPR019489 Clp ATPase, C-terminal AFK25_05640 1d74466abeb60842b975e837053fce06 460 SMART SM00382 47 349 7.6E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_05640 1d74466abeb60842b975e837053fce06 460 TIGRFAM TIGR00390 hslU: ATP-dependent protease HslVU, ATPase subunit 2 460 3.6E-214 T 11-10-2018 IPR004491 Heat shock protein HslU GO:0005524|GO:0005737|GO:0009376|GO:0016887|GO:0070011 AFK25_05640 1d74466abeb60842b975e837053fce06 460 Gene3D G3DSA:1.10.8.60 352 457 5.0E-41 T 11-10-2018 AFK25_05640 1d74466abeb60842b975e837053fce06 460 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 51 106 2.1E-6 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFK25_05640 1d74466abeb60842b975e837053fce06 460 Pfam PF07724 AAA domain (Cdc48 subfamily) 208 346 2.8E-41 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFK25_05640 1d74466abeb60842b975e837053fce06 460 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 352 427 8.5E-8 T 11-10-2018 IPR019489 Clp ATPase, C-terminal AFK25_04165 3aaf90c704cc2b83bca8f678a2f373c3 229 Pfam PF03591 AzlC protein 12 148 6.1E-40 T 11-10-2018 IPR011606 Branched-chain amino acid transport, permease AFK25_06470 f6821b3b82fd2af9899d6623c1d9fb70 254 SUPERFAMILY SSF55797 131 251 1.7E-27 T 11-10-2018 IPR035940 CAP superfamily AFK25_06470 f6821b3b82fd2af9899d6623c1d9fb70 254 Pfam PF00188 Cysteine-rich secretory protein family 139 250 2.7E-22 T 11-10-2018 IPR014044 CAP domain AFK25_06470 f6821b3b82fd2af9899d6623c1d9fb70 254 Gene3D G3DSA:3.40.33.10 19 252 3.1E-66 T 11-10-2018 IPR035940 CAP superfamily AFK25_06470 f6821b3b82fd2af9899d6623c1d9fb70 254 TIGRFAM TIGR02909 spore_YkwD: uncharacterized protein, YkwD family 131 253 6.0E-57 T 11-10-2018 IPR014258 CAP domain, YkwD-like AFK25_09670 8c951bba97d26e90f5bd452a596b890b 333 SUPERFAMILY SSF51395 1 322 1.26E-115 T 11-10-2018 AFK25_09670 8c951bba97d26e90f5bd452a596b890b 333 Hamap MF_01614 NADPH dehydrogenase [namA]. 1 333 64.772 T 11-10-2018 IPR023663 NADPH dehydrogenase GO:0003959|GO:0055114 AFK25_09670 8c951bba97d26e90f5bd452a596b890b 333 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 2 318 7.1E-89 T 11-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 AFK25_09670 8c951bba97d26e90f5bd452a596b890b 333 Gene3D G3DSA:3.20.20.70 1 333 3.4E-129 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_12615 332e7c94f4be79a5ac9af2942220eff0 304 SUPERFAMILY SSF54211 6 157 3.72E-31 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFK25_12615 332e7c94f4be79a5ac9af2942220eff0 304 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 89 100 - T 11-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 AFK25_12615 332e7c94f4be79a5ac9af2942220eff0 304 Gene3D G3DSA:3.30.230.10 5 163 5.4E-41 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFK25_12615 332e7c94f4be79a5ac9af2942220eff0 304 Pfam PF00288 GHMP kinases N terminal domain 83 143 5.4E-12 T 11-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 AFK25_12615 332e7c94f4be79a5ac9af2942220eff0 304 Pfam PF08544 GHMP kinases C terminal 204 281 1.9E-12 T 11-10-2018 IPR013750 GHMP kinase, C-terminal domain AFK25_12615 332e7c94f4be79a5ac9af2942220eff0 304 Gene3D G3DSA:3.30.70.890 164 287 4.6E-35 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily AFK25_12615 332e7c94f4be79a5ac9af2942220eff0 304 TIGRFAM TIGR00191 thrB: homoserine kinase 7 299 2.7E-85 T 11-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 AFK25_12615 332e7c94f4be79a5ac9af2942220eff0 304 SUPERFAMILY SSF55060 164 283 6.05E-30 T 11-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily AFK25_12615 332e7c94f4be79a5ac9af2942220eff0 304 Hamap MF_00384 Homoserine kinase [thrB]. 9 298 28.052 T 11-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 AFK25_12615 332e7c94f4be79a5ac9af2942220eff0 304 PIRSF PIRSF000676 4 300 2.9E-86 T 11-10-2018 IPR000870 Homoserine kinase GO:0004413|GO:0005524|GO:0006566 KEGG: 00260+2.7.1.39|MetaCyc: PWY-702 AFK25_12615 332e7c94f4be79a5ac9af2942220eff0 304 PRINTS PR00958 Homoserine kinase signature 248 263 6.9E-38 T 11-10-2018 AFK25_12615 332e7c94f4be79a5ac9af2942220eff0 304 PRINTS PR00958 Homoserine kinase signature 14 29 6.9E-38 T 11-10-2018 AFK25_12615 332e7c94f4be79a5ac9af2942220eff0 304 PRINTS PR00958 Homoserine kinase signature 96 111 6.9E-38 T 11-10-2018 AFK25_12615 332e7c94f4be79a5ac9af2942220eff0 304 PRINTS PR00958 Homoserine kinase signature 168 185 6.9E-38 T 11-10-2018 AFK25_12615 332e7c94f4be79a5ac9af2942220eff0 304 PRINTS PR00958 Homoserine kinase signature 130 143 6.9E-38 T 11-10-2018 AFK25_00260 4bd74c3bb3fa6e06f4a56df48dca2d3e 126 ProSitePatterns PS01094 Uncharacterized protein family UPF0076 signature. 99 117 - T 11-10-2018 IPR019897 RidA, conserved site Reactome: R-HSA-8849175 AFK25_00260 4bd74c3bb3fa6e06f4a56df48dca2d3e 126 Pfam PF01042 Endoribonuclease L-PSP 7 122 1.8E-47 T 11-10-2018 IPR006175 YjgF/YER057c/UK114 family Reactome: R-HSA-8849175 AFK25_00260 4bd74c3bb3fa6e06f4a56df48dca2d3e 126 Gene3D G3DSA:3.30.1330.40 1 124 5.0E-57 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFK25_00260 4bd74c3bb3fa6e06f4a56df48dca2d3e 126 TIGRFAM TIGR00004 TIGR00004: reactive intermediate/imine deaminase 1 122 9.8E-57 T 11-10-2018 IPR006056 RidA family Reactome: R-HSA-8849175 AFK25_00260 4bd74c3bb3fa6e06f4a56df48dca2d3e 126 SUPERFAMILY SSF55298 2 124 6.91E-49 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFK25_04055 09ee037fa7bf8b6fa398c2b8b59aa828 632 Gene3D G3DSA:3.40.50.300 282 549 5.9E-64 T 11-10-2018 AFK25_04055 09ee037fa7bf8b6fa398c2b8b59aa828 632 ProSitePatterns PS00211 ABC transporters family signature. 159 173 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_04055 09ee037fa7bf8b6fa398c2b8b59aa828 632 Pfam PF12848 ABC transporter 226 295 4.3E-15 T 11-10-2018 IPR032781 ABC-transporter extension domain AFK25_04055 09ee037fa7bf8b6fa398c2b8b59aa828 632 Gene3D G3DSA:3.40.50.300 1 281 6.1E-75 T 11-10-2018 AFK25_04055 09ee037fa7bf8b6fa398c2b8b59aa828 632 SUPERFAMILY SSF52540 313 519 5.92E-48 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_04055 09ee037fa7bf8b6fa398c2b8b59aa828 632 Pfam PF00005 ABC transporter 334 469 1.8E-25 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_04055 09ee037fa7bf8b6fa398c2b8b59aa828 632 Gene3D G3DSA:1.10.287.380 550 628 9.0E-12 T 11-10-2018 IPR037118 Valyl-tRNA synthetase, tRNA-binding arm superfamily GO:0000166|GO:0004832|GO:0005524|GO:0005737|GO:0006438 KEGG: 00970+6.1.1.9|Reactome: R-HSA-379716 AFK25_04055 09ee037fa7bf8b6fa398c2b8b59aa828 632 Pfam PF16326 ABC transporter C-terminal domain 558 624 5.5E-17 T 11-10-2018 IPR032524 ABC transporter Uup, C-terminal GO:0003677 AFK25_04055 09ee037fa7bf8b6fa398c2b8b59aa828 632 SUPERFAMILY SSF52540 4 240 8.94E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_04055 09ee037fa7bf8b6fa398c2b8b59aa828 632 Pfam PF00005 ABC transporter 20 187 1.1E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_04055 09ee037fa7bf8b6fa398c2b8b59aa828 632 SMART SM00382 28 232 4.6E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_04055 09ee037fa7bf8b6fa398c2b8b59aa828 632 SMART SM00382 343 515 2.9E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_06675 ca8607b7578bd1f9a9be52e1a216c048 714 SMART SM00436 130 225 1.9E-36 T 11-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 AFK25_06675 ca8607b7578bd1f9a9be52e1a216c048 714 Pfam PF01751 Toprim domain 3 138 1.9E-12 T 11-10-2018 IPR006171 TOPRIM domain AFK25_06675 ca8607b7578bd1f9a9be52e1a216c048 714 Gene3D G3DSA:2.70.20.10 219 480 3.9E-156 T 11-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 AFK25_06675 ca8607b7578bd1f9a9be52e1a216c048 714 Pfam PF13342 C-terminal repeat of topoisomerase 654 713 1.7E-19 T 11-10-2018 IPR025589 Topoisomerase C-terminal repeat AFK25_06675 ca8607b7578bd1f9a9be52e1a216c048 714 Gene3D G3DSA:1.10.460.10 164 595 3.9E-156 T 11-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 AFK25_06675 ca8607b7578bd1f9a9be52e1a216c048 714 SMART SM00437 273 550 9.2E-92 T 11-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 AFK25_06675 ca8607b7578bd1f9a9be52e1a216c048 714 Gene3D G3DSA:1.10.290.10 282 411 3.9E-156 T 11-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 AFK25_06675 ca8607b7578bd1f9a9be52e1a216c048 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 513 527 1.5E-26 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFK25_06675 ca8607b7578bd1f9a9be52e1a216c048 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 195 213 1.5E-26 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFK25_06675 ca8607b7578bd1f9a9be52e1a216c048 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 397 413 1.5E-26 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFK25_06675 ca8607b7578bd1f9a9be52e1a216c048 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 315 324 1.5E-26 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFK25_06675 ca8607b7578bd1f9a9be52e1a216c048 714 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 104 117 1.5E-26 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFK25_06675 ca8607b7578bd1f9a9be52e1a216c048 714 TIGRFAM TIGR01056 topB: DNA topoisomerase III 1 707 5.7E-195 T 11-10-2018 IPR005738 DNA topoisomerase III GO:0003677|GO:0003916|GO:0006265 AFK25_06675 ca8607b7578bd1f9a9be52e1a216c048 714 SMART SM00493 1 130 6.8E-12 T 11-10-2018 IPR006171 TOPRIM domain AFK25_06675 ca8607b7578bd1f9a9be52e1a216c048 714 Gene3D G3DSA:3.40.50.140 1 157 8.7E-52 T 11-10-2018 AFK25_06675 ca8607b7578bd1f9a9be52e1a216c048 714 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 310 324 - T 11-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 AFK25_06675 ca8607b7578bd1f9a9be52e1a216c048 714 Pfam PF01131 DNA topoisomerase 157 585 2.5E-124 T 11-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AFK25_06675 ca8607b7578bd1f9a9be52e1a216c048 714 SUPERFAMILY SSF56712 1 599 1.96E-178 T 11-10-2018 IPR023405 DNA topoisomerase, type IA, core domain AFK25_13895 b43397b254d82f7a4ba2dc2161a8478c 202 PIRSF PIRSF007510 12 193 3.2E-79 T 11-10-2018 IPR006340 Protein of unknown function DUF436 AFK25_13895 b43397b254d82f7a4ba2dc2161a8478c 202 Hamap MF_00800 UPF0340 protein . 1 202 101.286 T 11-10-2018 IPR006340 Protein of unknown function DUF436 AFK25_13895 b43397b254d82f7a4ba2dc2161a8478c 202 Gene3D G3DSA:3.40.50.10360 14 201 1.2E-80 T 11-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like AFK25_13895 b43397b254d82f7a4ba2dc2161a8478c 202 TIGRFAM TIGR01440 TIGR01440: TIGR01440 family protein 22 190 1.3E-75 T 11-10-2018 IPR006340 Protein of unknown function DUF436 AFK25_13895 b43397b254d82f7a4ba2dc2161a8478c 202 SUPERFAMILY SSF110710 14 198 7.59E-78 T 11-10-2018 IPR028345 Aminoglycoside 3-N-acetyltransferase-like AFK25_13895 b43397b254d82f7a4ba2dc2161a8478c 202 Pfam PF04260 Protein of unknown function (DUF436) 21 190 1.1E-77 T 11-10-2018 IPR006340 Protein of unknown function DUF436 AFK25_13895 b43397b254d82f7a4ba2dc2161a8478c 202 ProDom PD102102 UPF0340 3D-STRUCTURE YWLG SMU.87 STU1894 BT9727_4999 TRANSFERASE TTE0860 SPY1898/M5005_SPY1614 TT1679 22 191 3.0E-63 T 11-10-2018 IPR006340 Protein of unknown function DUF436 AFK25_10660 e28650fc6805726f704dfd9a069a3ff1 215 SUPERFAMILY SSF53335 3 214 6.15E-42 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_10660 e28650fc6805726f704dfd9a069a3ff1 215 Pfam PF01596 O-methyltransferase 43 212 1.9E-35 T 11-10-2018 IPR002935 O-methyltransferase, family 3 GO:0008171 AFK25_10660 e28650fc6805726f704dfd9a069a3ff1 215 Gene3D G3DSA:3.40.50.150 1 214 7.9E-64 T 11-10-2018 AFK25_03785 88d548849887ff844019aff588781497 305 Gene3D G3DSA:1.10.443.10 108 294 2.0E-43 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFK25_03785 88d548849887ff844019aff588781497 305 SUPERFAMILY SSF56349 4 293 7.36E-59 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFK25_03785 88d548849887ff844019aff588781497 305 Pfam PF00589 Phage integrase family 133 284 9.5E-35 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFK25_03785 88d548849887ff844019aff588781497 305 Gene3D G3DSA:1.10.150.130 2 107 4.7E-28 T 11-10-2018 IPR010998 Integrase/recombinase, N-terminal AFK25_03785 88d548849887ff844019aff588781497 305 Pfam PF13102 Phage integrase SAM-like domain 8 99 2.1E-13 T 11-10-2018 IPR025269 Phage integrase SAM-like domain AFK25_13060 0c980b440edd6622c75870c270cc9e33 950 Gene3D G3DSA:3.40.50.300 5 593 2.1E-261 T 11-10-2018 AFK25_13060 0c980b440edd6622c75870c270cc9e33 950 TIGRFAM TIGR00630 uvra: excinuclease ABC subunit A 4 921 0.0 T 11-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 AFK25_13060 0c980b440edd6622c75870c270cc9e33 950 Gene3D G3DSA:3.40.50.300 610 932 2.4E-148 T 11-10-2018 AFK25_13060 0c980b440edd6622c75870c270cc9e33 950 Gene3D G3DSA:1.20.1580.10 689 826 2.4E-148 T 11-10-2018 AFK25_13060 0c980b440edd6622c75870c270cc9e33 950 ProSitePatterns PS00211 ABC transporters family signature. 485 499 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_13060 0c980b440edd6622c75870c270cc9e33 950 SMART SM00382 23 562 15.0 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_13060 0c980b440edd6622c75870c270cc9e33 950 SMART SM00382 629 904 0.0013 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_13060 0c980b440edd6622c75870c270cc9e33 950 SUPERFAMILY SSF52540 6 567 6.95E-46 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_13060 0c980b440edd6622c75870c270cc9e33 950 Gene3D G3DSA:1.20.1580.10 90 490 2.1E-261 T 11-10-2018 AFK25_13060 0c980b440edd6622c75870c270cc9e33 950 Gene3D G3DSA:3.30.190.20 130 239 2.1E-261 T 11-10-2018 AFK25_13060 0c980b440edd6622c75870c270cc9e33 950 Gene3D G3DSA:1.10.8.280 284 401 2.1E-261 T 11-10-2018 AFK25_13060 0c980b440edd6622c75870c270cc9e33 950 ProSitePatterns PS00211 ABC transporters family signature. 826 840 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_13060 0c980b440edd6622c75870c270cc9e33 950 Hamap MF_00205 UvrABC system protein A [uvrA]. 1 936 23.827 T 11-10-2018 IPR004602 UvrABC system subunit A GO:0003677|GO:0006289|GO:0009380|GO:0016887 AFK25_13060 0c980b440edd6622c75870c270cc9e33 950 SUPERFAMILY SSF52540 614 906 3.76E-54 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_13060 0c980b440edd6622c75870c270cc9e33 950 Pfam PF00005 ABC transporter 620 856 1.2E-10 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_11245 ff471ccfb6f608888943ab9000a809ab 586 SUPERFAMILY SSF51905 6 426 2.98E-65 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_11245 ff471ccfb6f608888943ab9000a809ab 586 Gene3D G3DSA:3.90.700.10 258 367 5.4E-125 T 11-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFK25_11245 ff471ccfb6f608888943ab9000a809ab 586 Pfam PF00890 FAD binding domain 6 392 1.5E-89 T 11-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFK25_11245 ff471ccfb6f608888943ab9000a809ab 586 Gene3D G3DSA:3.50.50.60 6 403 5.4E-125 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_11245 ff471ccfb6f608888943ab9000a809ab 586 ProSitePatterns PS00504 Fumarate reductase / succinate dehydrogenase FAD-binding site. 39 48 - T 11-10-2018 IPR003952 Fumarate reductase/succinate dehydrogenase, FAD-binding site GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFK25_11245 ff471ccfb6f608888943ab9000a809ab 586 TIGRFAM TIGR01811 sdhA_Bsu: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 6 577 2.4E-282 T 11-10-2018 IPR011280 Succinate dehydrogenase/fumarate reductase flavoprotein subunit, low-GC Gram-positive bacteria KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279 AFK25_11245 ff471ccfb6f608888943ab9000a809ab 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.1E-7 T 11-10-2018 AFK25_11245 ff471ccfb6f608888943ab9000a809ab 586 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 356 378 1.1E-7 T 11-10-2018 AFK25_11245 ff471ccfb6f608888943ab9000a809ab 586 Gene3D G3DSA:1.20.58.100 423 539 2.2E-33 T 11-10-2018 AFK25_11245 ff471ccfb6f608888943ab9000a809ab 586 Pfam PF02910 Fumarate reductase flavoprotein C-term 452 577 1.4E-41 T 11-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFK25_11245 ff471ccfb6f608888943ab9000a809ab 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 2.7E-5 T 11-10-2018 AFK25_11245 ff471ccfb6f608888943ab9000a809ab 586 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 396 411 2.7E-5 T 11-10-2018 AFK25_11245 ff471ccfb6f608888943ab9000a809ab 586 SUPERFAMILY SSF46977 443 579 1.57E-46 T 11-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFK25_11245 ff471ccfb6f608888943ab9000a809ab 586 PIRSF PIRSF000171 336 575 1.3E-14 T 11-10-2018 AFK25_11245 ff471ccfb6f608888943ab9000a809ab 586 PIRSF PIRSF000171 2 240 1.2E-20 T 11-10-2018 AFK25_11245 ff471ccfb6f608888943ab9000a809ab 586 SUPERFAMILY SSF56425 231 353 1.64E-31 T 11-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFK25_02840 79c5c65bde8363883d12a516e015f0cd 277 SUPERFAMILY SSF109998 23 162 1.57E-20 T 11-10-2018 IPR027304 Trigger factor/SurA domain superfamily AFK25_02840 79c5c65bde8363883d12a516e015f0cd 277 ProSitePatterns PS01096 PpiC-type peptidyl-prolyl cis-trans isomerase signature. 161 182 - T 11-10-2018 IPR023058 Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site Reactome: R-HSA-1169408|Reactome: R-HSA-6804756|Reactome: R-HSA-6811555|Reactome: R-HSA-936440 AFK25_02840 79c5c65bde8363883d12a516e015f0cd 277 Gene3D G3DSA:3.10.50.40 127 222 1.5E-42 T 11-10-2018 AFK25_02840 79c5c65bde8363883d12a516e015f0cd 277 Pfam PF05698 Bacterial trigger factor protein (TF) C-terminus 32 112 1.4E-7 T 11-10-2018 IPR008880 Trigger factor, C-terminal GO:0006457|GO:0015031 AFK25_02840 79c5c65bde8363883d12a516e015f0cd 277 Hamap MF_01145 Foldase protein PrsA [prsA]. 1 277 21.424 T 11-10-2018 IPR023059 Foldase protein PrsA GO:0003755 AFK25_02840 79c5c65bde8363883d12a516e015f0cd 277 Pfam PF13616 PPIC-type PPIASE domain 125 223 4.9E-32 T 11-10-2018 AFK25_02840 79c5c65bde8363883d12a516e015f0cd 277 SUPERFAMILY SSF54534 117 222 3.6E-38 T 11-10-2018 AFK25_02840 79c5c65bde8363883d12a516e015f0cd 277 Gene3D G3DSA:1.10.3120.10 13 114 3.0E-7 T 11-10-2018 IPR037041 Trigger factor, C-terminal domain superfamily GO:0006457|GO:0015031 AFK25_06970 a004b4ce389e8f200f2de09aa5d86ee6 66 ProSitePatterns PS00352 'Cold-shock' domain signature. 15 33 - T 11-10-2018 IPR019844 Cold-shock conserved site AFK25_06970 a004b4ce389e8f200f2de09aa5d86ee6 66 Gene3D G3DSA:2.40.50.140 1 66 1.9E-30 T 11-10-2018 AFK25_06970 a004b4ce389e8f200f2de09aa5d86ee6 66 PIRSF PIRSF002599 1 66 1.5E-24 T 11-10-2018 IPR012156 Cold shock, CspA GO:0003676 AFK25_06970 a004b4ce389e8f200f2de09aa5d86ee6 66 Pfam PF00313 'Cold-shock' DNA-binding domain 3 65 3.0E-30 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFK25_06970 a004b4ce389e8f200f2de09aa5d86ee6 66 SUPERFAMILY SSF50249 1 65 6.21E-25 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_06970 a004b4ce389e8f200f2de09aa5d86ee6 66 PRINTS PR00050 Cold shock protein signature 24 33 1.6E-18 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFK25_06970 a004b4ce389e8f200f2de09aa5d86ee6 66 PRINTS PR00050 Cold shock protein signature 4 19 1.6E-18 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFK25_06970 a004b4ce389e8f200f2de09aa5d86ee6 66 PRINTS PR00050 Cold shock protein signature 39 57 1.6E-18 T 11-10-2018 IPR002059 Cold-shock protein, DNA-binding GO:0003677|GO:0006355 AFK25_06970 a004b4ce389e8f200f2de09aa5d86ee6 66 SMART SM00357 3 66 2.4E-30 T 11-10-2018 IPR011129 Cold shock domain GO:0003676 AFK25_01855 cb709288246185253e04948224799541 563 Gene3D G3DSA:1.20.1480.50 166 265 6.3E-20 T 11-10-2018 AFK25_01855 cb709288246185253e04948224799541 563 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 332 515 1.1E-51 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_01855 cb709288246185253e04948224799541 563 Pfam PF12729 Four helix bundle sensory module for signal transduction 3 179 1.9E-11 T 11-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain AFK25_01855 cb709288246185253e04948224799541 563 Pfam PF00672 HAMP domain 207 254 1.9E-14 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_01855 cb709288246185253e04948224799541 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 414 443 2.3E-21 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_01855 cb709288246185253e04948224799541 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 1 19 2.3E-21 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_01855 cb709288246185253e04948224799541 563 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 385 412 2.3E-21 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_01855 cb709288246185253e04948224799541 563 SMART SM00283 287 562 3.0E-87 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_01855 cb709288246185253e04948224799541 563 SMART SM00304 205 258 2.2E-15 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_01855 cb709288246185253e04948224799541 563 SMART SM00304 496 559 32.0 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_01855 cb709288246185253e04948224799541 563 SUPERFAMILY SSF58104 230 562 6.93E-77 T 11-10-2018 AFK25_01855 cb709288246185253e04948224799541 563 Gene3D G3DSA:1.10.287.950 290 562 2.9E-74 T 11-10-2018 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 SMART SM00957 5 382 2.7E-294 T 11-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 Gene3D G3DSA:3.10.450.50 773 834 1.9E-10 T 11-10-2018 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 Gene3D G3DSA:1.10.3060.10 571 772 0.0 T 11-10-2018 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 SUPERFAMILY SSF52540 5 395 1.47E-87 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 Pfam PF07516 SecA Wing and Scaffold domain 568 778 2.5E-65 T 11-10-2018 IPR011116 SecA Wing/Scaffold GO:0016020|GO:0017038 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 SUPERFAMILY SSF81886 571 824 6.8E-82 T 11-10-2018 IPR036266 SecA, Wing/Scaffold superfamily AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 TIGRFAM TIGR00963 secA: preprotein translocase, SecA subunit 26 496 5.1E-250 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 Pfam PF01043 SecA preprotein cross-linking domain 230 338 1.9E-43 T 11-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 SUPERFAMILY SSF52540 397 569 1.14E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 Gene3D G3DSA:1.10.1200.230 621 705 0.0 T 11-10-2018 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 SMART SM00958 226 338 5.6E-70 T 11-10-2018 IPR011130 SecA, preprotein cross-linking domain GO:0016020|GO:0017038 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 Gene3D G3DSA:3.40.50.300 14 396 0.0 T 11-10-2018 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 Hamap MF_01382 Protein translocase subunit SecA [secA]. 4 781 20.143 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 PRINTS PR00906 SecA protein signature 115 125 2.8E-72 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 PRINTS PR00906 SecA protein signature 356 373 2.8E-72 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 PRINTS PR00906 SecA protein signature 61 85 2.8E-72 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 PRINTS PR00906 SecA protein signature 319 341 2.8E-72 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 PRINTS PR00906 SecA protein signature 168 188 2.8E-72 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 PRINTS PR00906 SecA protein signature 99 113 2.8E-72 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 PRINTS PR00906 SecA protein signature 393 406 2.8E-72 T 11-10-2018 IPR000185 Protein translocase subunit SecA GO:0005524|GO:0006605|GO:0006886 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 Gene3D G3DSA:3.90.1440.10 227 348 0.0 T 11-10-2018 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 SUPERFAMILY SSF81767 225 348 7.98E-49 T 11-10-2018 IPR036670 SecA, preprotein cross-linking domain superfamily GO:0016020|GO:0017038 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 Pfam PF02810 SEC-C motif 816 834 2.9E-10 T 11-10-2018 IPR004027 SEC-C motif AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 Gene3D G3DSA:3.40.50.300 397 570 0.0 T 11-10-2018 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 Pfam PF07517 SecA DEAD-like domain 6 382 1.6E-133 T 11-10-2018 IPR011115 SecA DEAD-like, N-terminal GO:0005524|GO:0016020|GO:0017038 AFK25_13130 f896a48aa1dbef0472c0f90925a40cb4 834 ProSitePatterns PS01312 SecA family signature. 480 495 - T 11-10-2018 IPR020937 SecA conserved site GO:0006605|GO:0006886|GO:0016020 AFK25_01105 68eea934f56ac97f08df101ce38b45cd 116 PIRSF PIRSF033490 1 113 5.5E-40 T 11-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 AFK25_01105 68eea934f56ac97f08df101ce38b45cd 116 Gene3D G3DSA:2.30.30.110 1 116 2.0E-53 T 11-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor AFK25_01105 68eea934f56ac97f08df101ce38b45cd 116 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 4 111 9.1E-34 T 11-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 AFK25_01105 68eea934f56ac97f08df101ce38b45cd 116 SUPERFAMILY SSF50118 2 113 2.29E-42 T 11-10-2018 AFK25_00400 7628ef925e5c095d8014ca09e5d21a39 191 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 44 58 9.7E-6 T 11-10-2018 AFK25_00400 7628ef925e5c095d8014ca09e5d21a39 191 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 74 90 9.7E-6 T 11-10-2018 AFK25_00400 7628ef925e5c095d8014ca09e5d21a39 191 PRINTS PR00096 Glutamine amidotransferase superfamily signature 47 56 1.5E-13 T 11-10-2018 AFK25_00400 7628ef925e5c095d8014ca09e5d21a39 191 PRINTS PR00096 Glutamine amidotransferase superfamily signature 74 85 1.5E-13 T 11-10-2018 AFK25_00400 7628ef925e5c095d8014ca09e5d21a39 191 PRINTS PR00096 Glutamine amidotransferase superfamily signature 164 177 1.5E-13 T 11-10-2018 AFK25_00400 7628ef925e5c095d8014ca09e5d21a39 191 Pfam PF00117 Glutamine amidotransferase class-I 4 185 7.3E-57 T 11-10-2018 IPR017926 Glutamine amidotransferase AFK25_00400 7628ef925e5c095d8014ca09e5d21a39 191 SUPERFAMILY SSF52317 1 189 1.52E-57 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_00400 7628ef925e5c095d8014ca09e5d21a39 191 Gene3D G3DSA:3.40.50.880 1 190 1.1E-64 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_00400 7628ef925e5c095d8014ca09e5d21a39 191 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 186 1.1E-88 T 11-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFK25_00400 7628ef925e5c095d8014ca09e5d21a39 191 PRINTS PR00097 Anthranilate synthase component II signature 47 56 4.2E-37 T 11-10-2018 AFK25_00400 7628ef925e5c095d8014ca09e5d21a39 191 PRINTS PR00097 Anthranilate synthase component II signature 2 16 4.2E-37 T 11-10-2018 AFK25_00400 7628ef925e5c095d8014ca09e5d21a39 191 PRINTS PR00097 Anthranilate synthase component II signature 119 131 4.2E-37 T 11-10-2018 AFK25_00400 7628ef925e5c095d8014ca09e5d21a39 191 PRINTS PR00097 Anthranilate synthase component II signature 164 177 4.2E-37 T 11-10-2018 AFK25_00400 7628ef925e5c095d8014ca09e5d21a39 191 PRINTS PR00097 Anthranilate synthase component II signature 74 85 4.2E-37 T 11-10-2018 AFK25_00400 7628ef925e5c095d8014ca09e5d21a39 191 PRINTS PR00097 Anthranilate synthase component II signature 99 107 4.2E-37 T 11-10-2018 AFK25_02720 29ef5bd1421b7f32efb2a5fb86af3a67 338 SUPERFAMILY SSF69572 1 329 6.67E-75 T 11-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 AFK25_02720 29ef5bd1421b7f32efb2a5fb86af3a67 338 Pfam PF00899 ThiF family 4 240 1.1E-49 T 11-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 AFK25_02720 29ef5bd1421b7f32efb2a5fb86af3a67 338 Gene3D G3DSA:3.40.50.720 1 249 9.8E-67 T 11-10-2018 AFK25_09445 27ddf94033181fbf5af12719d79ae47d 70 Pfam PF14004 Protein of unknown function (DUF4227) 2 70 3.0E-32 T 11-10-2018 IPR025321 Protein of unknown function DUF4227 AFK25_04475 cb8827a6170cbd347d1c0c9193119d40 211 Gene3D G3DSA:3.40.50.2300 1 115 4.9E-33 T 11-10-2018 AFK25_04475 cb8827a6170cbd347d1c0c9193119d40 211 SMART SM00448 1 100 1.9E-30 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_04475 cb8827a6170cbd347d1c0c9193119d40 211 SMART SM00862 134 207 1.3E-27 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFK25_04475 cb8827a6170cbd347d1c0c9193119d40 211 Pfam PF00072 Response regulator receiver domain 1 100 1.3E-25 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_04475 cb8827a6170cbd347d1c0c9193119d40 211 SUPERFAMILY SSF52172 1 167 4.98E-37 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_04475 cb8827a6170cbd347d1c0c9193119d40 211 Pfam PF00486 Transcriptional regulatory protein, C terminal 135 207 1.2E-25 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFK25_04475 cb8827a6170cbd347d1c0c9193119d40 211 Gene3D G3DSA:1.10.10.10 116 211 1.0E-33 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_13520 565c07730253b27aac057f460bcdd088 288 TIGRFAM TIGR04398 SLAP_DUP: SLAP domain 36 158 1.2E-41 T 11-10-2018 IPR030910 SLAP domain, Bacillus-type AFK25_13520 565c07730253b27aac057f460bcdd088 288 TIGRFAM TIGR04398 SLAP_DUP: SLAP domain 164 286 3.9E-45 T 11-10-2018 IPR030910 SLAP domain, Bacillus-type AFK25_13520 565c07730253b27aac057f460bcdd088 288 TIGRFAM TIGR04399 acc_Sec_SLAP: accessory Sec system S-layer assembly protein 4 288 1.3E-134 T 11-10-2018 IPR030911 Accessory Sec system S-layer assembly protein AFK25_04900 6fbf26fa1650616bb438e227ebf52334 488 Gene3D G3DSA:3.90.1150.10 314 403 3.4E-6 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_04900 6fbf26fa1650616bb438e227ebf52334 488 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 6 370 7.2E-113 T 11-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 AFK25_04900 6fbf26fa1650616bb438e227ebf52334 488 Gene3D G3DSA:3.90.105.10 420 477 1.5E-18 T 11-10-2018 AFK25_04900 6fbf26fa1650616bb438e227ebf52334 488 SUPERFAMILY SSF53383 6 386 2.15E-97 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_04900 6fbf26fa1650616bb438e227ebf52334 488 ProSitePatterns PS00703 Orn/Lys/Arg decarboxylases family 1 pyridoxal-P attachment site. 221 235 - T 11-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 AFK25_04900 6fbf26fa1650616bb438e227ebf52334 488 Gene3D G3DSA:3.40.640.10 6 283 6.4E-94 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_04900 6fbf26fa1650616bb438e227ebf52334 488 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 386 460 2.5E-11 T 11-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 AFK25_04900 6fbf26fa1650616bb438e227ebf52334 488 SUPERFAMILY SSF55904 341 486 5.75E-42 T 11-10-2018 IPR036633 Orn/Lys/Arg decarboxylase, C-terminal domain superfamily GO:0003824 AFK25_02645 e581ee2b7e52dcc9f09959600f15317d 321 SUPERFAMILY SSF117892 59 195 1.26E-20 T 11-10-2018 IPR036013 Band 7/SPFH domain superfamily AFK25_02645 e581ee2b7e52dcc9f09959600f15317d 321 Gene3D G3DSA:3.30.479.30 82 192 5.9E-21 T 11-10-2018 AFK25_02645 e581ee2b7e52dcc9f09959600f15317d 321 Pfam PF01145 SPFH domain / Band 7 family 29 216 3.1E-25 T 11-10-2018 IPR001107 Band 7 domain AFK25_02645 e581ee2b7e52dcc9f09959600f15317d 321 SMART SM00244 25 202 1.6E-25 T 11-10-2018 IPR001107 Band 7 domain AFK25_02645 e581ee2b7e52dcc9f09959600f15317d 321 TIGRFAM TIGR01933 hflK: HflK protein 28 303 1.4E-69 T 11-10-2018 IPR010201 HflK GO:0016021 AFK25_01375 31657c8647075bbe211d1facd1aed674 668 Pfam PF03120 NAD-dependent DNA ligase OB-fold domain 320 396 1.7E-33 T 11-10-2018 IPR004150 NAD-dependent DNA ligase, OB-fold GO:0003911|GO:0006260|GO:0006281 AFK25_01375 31657c8647075bbe211d1facd1aed674 668 SUPERFAMILY SSF56091 7 316 2.59E-126 T 11-10-2018 AFK25_01375 31657c8647075bbe211d1facd1aed674 668 SUPERFAMILY SSF52113 593 667 1.28E-21 T 11-10-2018 IPR036420 BRCT domain superfamily AFK25_01375 31657c8647075bbe211d1facd1aed674 668 Gene3D G3DSA:2.40.50.140 316 387 1.4E-29 T 11-10-2018 AFK25_01375 31657c8647075bbe211d1facd1aed674 668 Gene3D G3DSA:1.10.287.610 4 75 1.5E-30 T 11-10-2018 AFK25_01375 31657c8647075bbe211d1facd1aed674 668 TIGRFAM TIGR00575 dnlj: DNA ligase, NAD-dependent 16 662 4.8E-280 T 11-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AFK25_01375 31657c8647075bbe211d1facd1aed674 668 Pfam PF01653 NAD-dependent DNA ligase adenylation domain 9 316 2.5E-131 T 11-10-2018 IPR013839 NAD-dependent DNA ligase, adenylation GO:0003911 AFK25_01375 31657c8647075bbe211d1facd1aed674 668 Gene3D G3DSA:2.20.70.80 390 426 3.8E-11 T 11-10-2018 AFK25_01375 31657c8647075bbe211d1facd1aed674 668 SUPERFAMILY SSF47781 402 582 5.19E-68 T 11-10-2018 IPR010994 RuvA domain 2-like AFK25_01375 31657c8647075bbe211d1facd1aed674 668 SMART SM00532 8 445 6.4E-288 T 11-10-2018 IPR013840 NAD-dependent DNA ligase, N-terminal GO:0003911 AFK25_01375 31657c8647075bbe211d1facd1aed674 668 ProSitePatterns PS01056 NAD-dependent DNA ligase signature 2. 329 344 - T 11-10-2018 IPR033136 NAD-dependent DNA ligase, conserved site AFK25_01375 31657c8647075bbe211d1facd1aed674 668 SMART SM00292 592 668 3.7E-15 T 11-10-2018 IPR001357 BRCT domain AFK25_01375 31657c8647075bbe211d1facd1aed674 668 Gene3D G3DSA:3.30.470.90 76 315 7.8E-103 T 11-10-2018 AFK25_01375 31657c8647075bbe211d1facd1aed674 668 Gene3D G3DSA:1.10.150.20 429 501 2.6E-32 T 11-10-2018 AFK25_01375 31657c8647075bbe211d1facd1aed674 668 Gene3D G3DSA:3.40.50.10190 589 668 1.0E-28 T 11-10-2018 IPR036420 BRCT domain superfamily AFK25_01375 31657c8647075bbe211d1facd1aed674 668 Pfam PF00533 BRCA1 C Terminus (BRCT) domain 594 663 2.3E-16 T 11-10-2018 IPR001357 BRCT domain AFK25_01375 31657c8647075bbe211d1facd1aed674 668 ProSitePatterns PS01055 NAD-dependent DNA ligase signature 1. 117 146 - T 11-10-2018 IPR018239 NAD-dependent DNA ligase, active site AFK25_01375 31657c8647075bbe211d1facd1aed674 668 Gene3D G3DSA:1.10.150.20 502 583 2.1E-30 T 11-10-2018 AFK25_01375 31657c8647075bbe211d1facd1aed674 668 SMART SM00278 541 560 7.5 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFK25_01375 31657c8647075bbe211d1facd1aed674 668 SMART SM00278 477 496 5.1 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFK25_01375 31657c8647075bbe211d1facd1aed674 668 SMART SM00278 443 462 1.4 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFK25_01375 31657c8647075bbe211d1facd1aed674 668 PIRSF PIRSF001604 1 668 5.2E-273 T 11-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AFK25_01375 31657c8647075bbe211d1facd1aed674 668 Pfam PF03119 NAD-dependent DNA ligase C4 zinc finger domain 405 431 5.8E-10 T 11-10-2018 IPR004149 Zinc-finger, NAD-dependent DNA ligase C4-type GO:0003911|GO:0006260|GO:0006281 AFK25_01375 31657c8647075bbe211d1facd1aed674 668 Pfam PF14520 Helix-hairpin-helix domain 443 497 4.1E-7 T 11-10-2018 AFK25_01375 31657c8647075bbe211d1facd1aed674 668 Hamap MF_01588 DNA ligase [ligA]. 7 666 54.346 T 11-10-2018 IPR001679 NAD-dependent DNA ligase GO:0003911|GO:0006260|GO:0006281 AFK25_01375 31657c8647075bbe211d1facd1aed674 668 SUPERFAMILY SSF50249 315 399 2.06E-27 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_01375 31657c8647075bbe211d1facd1aed674 668 Pfam PF12826 Helix-hairpin-helix motif 507 570 2.9E-26 T 11-10-2018 AFK25_02215 09f4d67d922e675587c0140701949934 631 SMART SM00763 21 371 2.9E-198 T 11-10-2018 IPR013153 PrkA AAA domain AFK25_02215 09f4d67d922e675587c0140701949934 631 PIRSF PIRSF000549 1 631 5.8E-267 T 11-10-2018 IPR016230 Serine-protein kinase, PrkA GO:0004672 AFK25_02215 09f4d67d922e675587c0140701949934 631 SUPERFAMILY SSF52540 68 468 8.47E-14 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_02215 09f4d67d922e675587c0140701949934 631 Pfam PF06798 PrkA serine protein kinase C-terminal domain 375 624 2.3E-94 T 11-10-2018 IPR010650 PrkA C-terminal domain AFK25_02215 09f4d67d922e675587c0140701949934 631 Pfam PF08298 PrkA AAA domain 22 370 1.4E-154 T 11-10-2018 IPR013153 PrkA AAA domain AFK25_08860 3764155611c5266d62a7c489af4aad4e 417 SUPERFAMILY SSF48452 203 407 4.05E-29 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_08860 3764155611c5266d62a7c489af4aad4e 417 Pfam PF13176 Tetratricopeptide repeat 175 197 0.0025 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_08860 3764155611c5266d62a7c489af4aad4e 417 Pfam PF13176 Tetratricopeptide repeat 139 161 0.0029 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_08860 3764155611c5266d62a7c489af4aad4e 417 SMART SM00028 134 167 1.2 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_08860 3764155611c5266d62a7c489af4aad4e 417 SMART SM00028 237 270 37.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_08860 3764155611c5266d62a7c489af4aad4e 417 SMART SM00028 170 203 16.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_08860 3764155611c5266d62a7c489af4aad4e 417 SMART SM00028 271 304 0.2 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_08860 3764155611c5266d62a7c489af4aad4e 417 SMART SM00028 339 372 8.1 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_08860 3764155611c5266d62a7c489af4aad4e 417 SMART SM00028 305 338 440.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_08860 3764155611c5266d62a7c489af4aad4e 417 SMART SM00028 373 406 0.11 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_08860 3764155611c5266d62a7c489af4aad4e 417 Gene3D G3DSA:1.25.40.10 200 303 1.4E-14 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_08860 3764155611c5266d62a7c489af4aad4e 417 Gene3D G3DSA:1.25.40.10 304 416 4.0E-17 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_08860 3764155611c5266d62a7c489af4aad4e 417 Pfam PF14559 Tetratricopeptide repeat 354 413 2.6E-7 T 11-10-2018 AFK25_08860 3764155611c5266d62a7c489af4aad4e 417 SUPERFAMILY SSF48452 33 198 9.1E-18 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_08860 3764155611c5266d62a7c489af4aad4e 417 Gene3D G3DSA:1.25.40.10 3 199 1.9E-24 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_08860 3764155611c5266d62a7c489af4aad4e 417 Pfam PF07719 Tetratricopeptide repeat 272 303 1.8E-5 T 11-10-2018 IPR013105 Tetratricopeptide repeat 2 AFK25_06450 a43a4810e129d0f934f2952b4e713a85 216 Pfam PF00440 Bacterial regulatory proteins, tetR family 16 61 2.2E-10 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_06450 a43a4810e129d0f934f2952b4e713a85 216 Gene3D G3DSA:1.10.10.60 3 58 2.0E-14 T 11-10-2018 AFK25_06450 a43a4810e129d0f934f2952b4e713a85 216 SUPERFAMILY SSF46689 5 80 2.15E-15 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_06450 a43a4810e129d0f934f2952b4e713a85 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 37 60 7.2E-7 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_06450 a43a4810e129d0f934f2952b4e713a85 216 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 16 29 7.2E-7 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_06450 a43a4810e129d0f934f2952b4e713a85 216 Gene3D G3DSA:1.10.357.10 59 216 1.7E-43 T 11-10-2018 AFK25_06450 a43a4810e129d0f934f2952b4e713a85 216 ProSitePatterns PS01081 TetR-type HTH domain signature. 28 58 - T 11-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFK25_06450 a43a4810e129d0f934f2952b4e713a85 216 SUPERFAMILY SSF48498 85 216 3.02E-24 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFK25_14655 be43b3b552562f37c8ee40142e5aa750 255 PRINTS PR01900 YidC translocation/secretion protein signature 196 220 1.2E-6 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFK25_14655 be43b3b552562f37c8ee40142e5aa750 255 PRINTS PR01900 YidC translocation/secretion protein signature 174 189 1.2E-6 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFK25_14655 be43b3b552562f37c8ee40142e5aa750 255 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 1 245 32.639 T 11-10-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes GO:0016021|GO:0032977 AFK25_14655 be43b3b552562f37c8ee40142e5aa750 255 Pfam PF02096 60Kd inner membrane protein 58 240 7.5E-61 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFK25_14655 be43b3b552562f37c8ee40142e5aa750 255 PRINTS PR00701 60kDa inner membrane protein signature 123 146 2.6E-15 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFK25_14655 be43b3b552562f37c8ee40142e5aa750 255 PRINTS PR00701 60kDa inner membrane protein signature 207 230 2.6E-15 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFK25_14655 be43b3b552562f37c8ee40142e5aa750 255 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 57 240 2.7E-67 T 11-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_11365 5d8506c6653beda13df20711fa6c3c10 149 SMART SM00347 28 128 2.9E-18 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_11365 5d8506c6653beda13df20711fa6c3c10 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 88 104 1.1E-12 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_11365 5d8506c6653beda13df20711fa6c3c10 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 52 68 1.1E-12 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_11365 5d8506c6653beda13df20711fa6c3c10 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 69 84 1.1E-12 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_11365 5d8506c6653beda13df20711fa6c3c10 149 PRINTS PR00598 Bacterial regulatory protein MarR family signature 118 138 1.1E-12 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_11365 5d8506c6653beda13df20711fa6c3c10 149 Pfam PF01047 MarR family 36 92 1.0E-12 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_11365 5d8506c6653beda13df20711fa6c3c10 149 Gene3D G3DSA:1.10.10.10 3 145 4.2E-32 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_11365 5d8506c6653beda13df20711fa6c3c10 149 SUPERFAMILY SSF46785 7 145 4.74E-29 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_07745 e78595a64cd3f7d89fd79e73efd31e80 455 SUPERFAMILY SSF58104 216 451 3.14E-55 T 11-10-2018 AFK25_07745 e78595a64cd3f7d89fd79e73efd31e80 455 SMART SM00283 210 450 6.0E-42 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_07745 e78595a64cd3f7d89fd79e73efd31e80 455 Pfam PF11563 Protoglobin 52 201 2.7E-42 T 11-10-2018 AFK25_07745 e78595a64cd3f7d89fd79e73efd31e80 455 Gene3D G3DSA:1.10.490.10 51 207 3.8E-46 T 11-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 AFK25_07745 e78595a64cd3f7d89fd79e73efd31e80 455 Gene3D G3DSA:1.10.287.950 223 455 2.3E-46 T 11-10-2018 AFK25_07745 e78595a64cd3f7d89fd79e73efd31e80 455 SUPERFAMILY SSF46458 38 195 1.87E-38 T 11-10-2018 IPR009050 Globin-like superfamily AFK25_07745 e78595a64cd3f7d89fd79e73efd31e80 455 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 283 444 2.0E-31 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_00510 2e0000709e697966e2e9b23d34ce8aed 245 SUPERFAMILY SSF75217 65 241 5.56E-50 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases AFK25_00510 2e0000709e697966e2e9b23d34ce8aed 245 Pfam PF00588 SpoU rRNA Methylase family 94 234 5.1E-39 T 11-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AFK25_00510 2e0000709e697966e2e9b23d34ce8aed 245 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 2 240 1.2E-85 T 11-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 AFK25_00510 2e0000709e697966e2e9b23d34ce8aed 245 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 3 76 7.8E-25 T 11-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 AFK25_00510 2e0000709e697966e2e9b23d34ce8aed 245 SMART SM00967 3 77 3.2E-25 T 11-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 AFK25_00510 2e0000709e697966e2e9b23d34ce8aed 245 SUPERFAMILY SSF55315 2 74 3.63E-19 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like AFK25_00510 2e0000709e697966e2e9b23d34ce8aed 245 Gene3D G3DSA:3.30.1330.30 1 71 4.9E-15 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like AFK25_00510 2e0000709e697966e2e9b23d34ce8aed 245 Gene3D G3DSA:3.40.1280.10 72 241 5.6E-56 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFK25_01245 6c3cf796b282bc15b1a26b803c0bffad 538 SUPERFAMILY SSF54849 136 204 6.64E-26 T 11-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily AFK25_01245 6c3cf796b282bc15b1a26b803c0bffad 538 Pfam PF00118 TCP-1/cpn60 chaperonin family 22 522 5.5E-104 T 11-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 AFK25_01245 6c3cf796b282bc15b1a26b803c0bffad 538 Gene3D G3DSA:1.10.560.10 7 518 3.4E-239 T 11-10-2018 IPR027413 GroEL-like equatorial domain superfamily AFK25_01245 6c3cf796b282bc15b1a26b803c0bffad 538 Gene3D G3DSA:3.50.7.10 190 370 3.4E-239 T 11-10-2018 IPR027409 GroEL-like apical domain superfamily AFK25_01245 6c3cf796b282bc15b1a26b803c0bffad 538 SUPERFAMILY SSF52029 183 374 9.42E-85 T 11-10-2018 IPR027409 GroEL-like apical domain superfamily AFK25_01245 6c3cf796b282bc15b1a26b803c0bffad 538 TIGRFAM TIGR02348 GroEL: chaperonin GroL 2 524 2.0E-262 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFK25_01245 6c3cf796b282bc15b1a26b803c0bffad 538 Hamap MF_00600 60 kDa chaperonin [groL]. 1 537 42.987 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFK25_01245 6c3cf796b282bc15b1a26b803c0bffad 538 Gene3D G3DSA:3.30.260.10 135 408 3.4E-239 T 11-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily AFK25_01245 6c3cf796b282bc15b1a26b803c0bffad 538 ProSitePatterns PS00296 Chaperonins cpn60 signature. 403 414 - T 11-10-2018 IPR018370 Chaperonin Cpn60, conserved site GO:0005524|GO:0005737|GO:0006457 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFK25_01245 6c3cf796b282bc15b1a26b803c0bffad 538 PRINTS PR00298 60kDa chaperonin signature 266 289 1.6E-73 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFK25_01245 6c3cf796b282bc15b1a26b803c0bffad 538 PRINTS PR00298 60kDa chaperonin signature 82 109 1.6E-73 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFK25_01245 6c3cf796b282bc15b1a26b803c0bffad 538 PRINTS PR00298 60kDa chaperonin signature 348 373 1.6E-73 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFK25_01245 6c3cf796b282bc15b1a26b803c0bffad 538 PRINTS PR00298 60kDa chaperonin signature 26 52 1.6E-73 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFK25_01245 6c3cf796b282bc15b1a26b803c0bffad 538 PRINTS PR00298 60kDa chaperonin signature 396 417 1.6E-73 T 11-10-2018 IPR001844 Chaperonin Cpn60 GO:0005737|GO:0042026 Reactome: R-HSA-1268020|Reactome: R-HSA-8869496 AFK25_01245 6c3cf796b282bc15b1a26b803c0bffad 538 SUPERFAMILY SSF48592 5 518 2.75E-82 T 11-10-2018 IPR027413 GroEL-like equatorial domain superfamily AFK25_07715 280798119642c507474c8ca2877e67db 503 Gene3D G3DSA:1.10.1370.30 3 503 8.3E-205 T 11-10-2018 AFK25_07715 280798119642c507474c8ca2877e67db 503 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 249 268 4.6E-79 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 AFK25_07715 280798119642c507474c8ca2877e67db 503 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 152 172 4.6E-79 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 AFK25_07715 280798119642c507474c8ca2877e67db 503 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 405 426 4.6E-79 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 AFK25_07715 280798119642c507474c8ca2877e67db 503 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 296 312 4.6E-79 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 AFK25_07715 280798119642c507474c8ca2877e67db 503 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 336 355 4.6E-79 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 AFK25_07715 280798119642c507474c8ca2877e67db 503 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 269 288 4.6E-79 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 AFK25_07715 280798119642c507474c8ca2877e67db 503 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 232 248 4.6E-79 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 AFK25_07715 280798119642c507474c8ca2877e67db 503 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 382 399 4.6E-79 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 AFK25_07715 280798119642c507474c8ca2877e67db 503 PRINTS PR00998 Carboxypeptidase Taq (M32) metallopeptidase signature 449 467 4.6E-79 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 AFK25_07715 280798119642c507474c8ca2877e67db 503 PIRSF PIRSF006615 4 503 6.7E-194 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 AFK25_07715 280798119642c507474c8ca2877e67db 503 SUPERFAMILY SSF55486 9 497 1.95E-111 T 11-10-2018 AFK25_07715 280798119642c507474c8ca2877e67db 503 Pfam PF02074 Carboxypeptidase Taq (M32) metallopeptidase 5 497 9.1E-218 T 11-10-2018 IPR001333 Peptidase M32, carboxypeptidase Taq GO:0004181|GO:0006508 AFK25_09840 b18235833d01751e1faa1f59a4986739 283 Pfam PF00763 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain 5 120 3.6E-41 T 11-10-2018 IPR020630 Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFK25_09840 b18235833d01751e1faa1f59a4986739 283 SUPERFAMILY SSF51735 122 278 1.08E-52 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_09840 b18235833d01751e1faa1f59a4986739 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 255 273 6.0E-87 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFK25_09840 b18235833d01751e1faa1f59a4986739 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 33 55 6.0E-87 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFK25_09840 b18235833d01751e1faa1f59a4986739 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 154 174 6.0E-87 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFK25_09840 b18235833d01751e1faa1f59a4986739 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 238 254 6.0E-87 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFK25_09840 b18235833d01751e1faa1f59a4986739 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 203 232 6.0E-87 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFK25_09840 b18235833d01751e1faa1f59a4986739 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 74 101 6.0E-87 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFK25_09840 b18235833d01751e1faa1f59a4986739 283 PRINTS PR00085 Tetrahydrofolate dehydrogenase/cyclohydrolase family signature 109 130 6.0E-87 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFK25_09840 b18235833d01751e1faa1f59a4986739 283 Pfam PF02882 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain 123 280 5.9E-73 T 11-10-2018 IPR020631 Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain GO:0004488 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFK25_09840 b18235833d01751e1faa1f59a4986739 283 Gene3D G3DSA:3.40.50.10860 8 275 4.7E-116 T 11-10-2018 AFK25_09840 b18235833d01751e1faa1f59a4986739 283 Hamap MF_01576 Bifunctional protein FolD [folD]. 3 282 39.515 T 11-10-2018 IPR000672 Tetrahydrofolate dehydrogenase/cyclohydrolase GO:0004488|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFK25_09840 b18235833d01751e1faa1f59a4986739 283 Gene3D G3DSA:3.40.50.720 6 258 4.7E-116 T 11-10-2018 AFK25_09840 b18235833d01751e1faa1f59a4986739 283 ProSitePatterns PS00767 Tetrahydrofolate dehydrogenase/cyclohydrolase signature 2. 259 267 - T 11-10-2018 IPR020867 Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site GO:0003824|GO:0055114 KEGG: 00670+1.5.1.5+3.5.4.9|KEGG: 00720+1.5.1.5+3.5.4.9|MetaCyc: PWY-1722|MetaCyc: PWY-2201|MetaCyc: PWY-3841|MetaCyc: PWY-5030|MetaCyc: PWY-5497|MetaCyc: PWY-6613|MetaCyc: PWY-7909|Reactome: R-HSA-196757 AFK25_09840 b18235833d01751e1faa1f59a4986739 283 SUPERFAMILY SSF53223 1 121 1.82E-40 T 11-10-2018 AFK25_00685 3aaa735e774504b14e67446eb0f01229 120 Gene3D G3DSA:3.30.420.100 5 120 6.2E-50 T 11-10-2018 AFK25_00685 3aaa735e774504b14e67446eb0f01229 120 SUPERFAMILY SSF53137 7 118 2.4E-57 T 11-10-2018 AFK25_00685 3aaa735e774504b14e67446eb0f01229 120 Pfam PF00861 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast 6 120 1.1E-53 T 11-10-2018 IPR005484 Ribosomal protein L18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00685 3aaa735e774504b14e67446eb0f01229 120 Hamap MF_01337_B 50S ribosomal protein L18 [rplR]. 6 120 31.299 T 11-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00685 3aaa735e774504b14e67446eb0f01229 120 TIGRFAM TIGR00060 L18_bact: ribosomal protein uL18 7 120 6.3E-48 T 11-10-2018 IPR004389 Ribosomal protein L18, bacterial-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_05080 aa5b1d67ac83b6f223ce638df1241de3 336 Gene3D G3DSA:3.40.33.10 18 330 4.4E-101 T 11-10-2018 IPR035940 CAP superfamily AFK25_05080 aa5b1d67ac83b6f223ce638df1241de3 336 SUPERFAMILY SSF55797 211 328 6.45E-23 T 11-10-2018 IPR035940 CAP superfamily AFK25_05080 aa5b1d67ac83b6f223ce638df1241de3 336 Pfam PF14504 CAP-associated N-terminal 49 187 2.2E-47 T 11-10-2018 IPR029410 CAP-associated domain AFK25_05080 aa5b1d67ac83b6f223ce638df1241de3 336 Pfam PF00188 Cysteine-rich secretory protein family 218 325 3.1E-20 T 11-10-2018 IPR014044 CAP domain AFK25_02895 82fd3f580388d74a0f69a712d037531c 762 TIGRFAM TIGR03061 pip_yhgE_Nterm: YhgE/Pip N-terminal domain 2 165 6.4E-67 T 11-10-2018 IPR017500 Phage infection protein, YhgE, N-terminal AFK25_02895 82fd3f580388d74a0f69a712d037531c 762 SUPERFAMILY SSF101967 385 521 7.06E-7 T 11-10-2018 AFK25_02895 82fd3f580388d74a0f69a712d037531c 762 TIGRFAM TIGR03062 pip_yhgE_Cterm: YhgE/Pip C-terminal domain 545 748 7.2E-70 T 11-10-2018 IPR017501 Phage infection protein, YhgE, C-terminal AFK25_02895 82fd3f580388d74a0f69a712d037531c 762 SUPERFAMILY SSF58104 157 351 6.02E-7 T 11-10-2018 AFK25_02895 82fd3f580388d74a0f69a712d037531c 762 Pfam PF12698 ABC-2 family transporter protein 17 163 1.0E-11 T 11-10-2018 AFK25_02895 82fd3f580388d74a0f69a712d037531c 762 Pfam PF12698 ABC-2 family transporter protein 540 738 5.2E-16 T 11-10-2018 AFK25_02895 82fd3f580388d74a0f69a712d037531c 762 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 381 407 2.0E-4 T 11-10-2018 IPR023908 xxxLxxG heptad repeat AFK25_02895 82fd3f580388d74a0f69a712d037531c 762 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 228 251 6.1E-6 T 11-10-2018 IPR023908 xxxLxxG heptad repeat AFK25_02895 82fd3f580388d74a0f69a712d037531c 762 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 260 282 3.7E-4 T 11-10-2018 IPR023908 xxxLxxG heptad repeat AFK25_02895 82fd3f580388d74a0f69a712d037531c 762 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 169 195 2.9E-4 T 11-10-2018 IPR023908 xxxLxxG heptad repeat AFK25_02895 82fd3f580388d74a0f69a712d037531c 762 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 465 491 1.7E-6 T 11-10-2018 IPR023908 xxxLxxG heptad repeat AFK25_02895 82fd3f580388d74a0f69a712d037531c 762 TIGRFAM TIGR03057 xxxLxxG_by_4: X-X-X-Leu-X-X-Gly heptad repeats 492 519 6.5E-10 T 11-10-2018 IPR023908 xxxLxxG heptad repeat AFK25_04695 e12068dc1d1eddddad3b2a16c70ad73c 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 394 7.3E-12 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04695 e12068dc1d1eddddad3b2a16c70ad73c 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 347 361 7.3E-12 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04695 e12068dc1d1eddddad3b2a16c70ad73c 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 413 7.3E-12 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04695 e12068dc1d1eddddad3b2a16c70ad73c 418 Gene3D G3DSA:1.10.287.130 205 261 1.5E-15 T 11-10-2018 AFK25_04695 e12068dc1d1eddddad3b2a16c70ad73c 418 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 308 414 3.2E-20 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_04695 e12068dc1d1eddddad3b2a16c70ad73c 418 SMART SM00387 308 416 1.1E-27 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_04695 e12068dc1d1eddddad3b2a16c70ad73c 418 Pfam PF00512 His Kinase A (phospho-acceptor) domain 204 263 7.6E-12 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_04695 e12068dc1d1eddddad3b2a16c70ad73c 418 SMART SM00388 202 267 1.2E-11 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_04695 e12068dc1d1eddddad3b2a16c70ad73c 418 Pfam PF07694 5TMR of 5TMR-LYT 29 178 1.3E-12 T 11-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 AFK25_04695 e12068dc1d1eddddad3b2a16c70ad73c 418 SUPERFAMILY SSF47384 198 263 1.61E-12 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFK25_04695 e12068dc1d1eddddad3b2a16c70ad73c 418 Gene3D G3DSA:3.30.565.10 262 414 3.3E-36 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_04695 e12068dc1d1eddddad3b2a16c70ad73c 418 SUPERFAMILY SSF55874 261 414 1.57E-33 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_00620 4746ceeb716c7030ff840f36b8724a98 276 SUPERFAMILY SSF50104 126 273 1.75E-62 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily AFK25_00620 4746ceeb716c7030ff840f36b8724a98 276 SMART SM01383 42 118 3.2E-47 T 11-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00620 4746ceeb716c7030ff840f36b8724a98 276 Hamap MF_01320_B 50S ribosomal protein L2 [rplB]. 1 275 50.495 T 11-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 AFK25_00620 4746ceeb716c7030ff840f36b8724a98 276 PIRSF PIRSF002158 3 276 7.8E-104 T 11-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00620 4746ceeb716c7030ff840f36b8724a98 276 Gene3D G3DSA:2.40.50.140 1 114 1.4E-50 T 11-10-2018 AFK25_00620 4746ceeb716c7030ff840f36b8724a98 276 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 42 118 1.1E-34 T 11-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00620 4746ceeb716c7030ff840f36b8724a98 276 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 125 251 1.3E-58 T 11-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 AFK25_00620 4746ceeb716c7030ff840f36b8724a98 276 ProSitePatterns PS00467 Ribosomal protein L2 signature. 218 229 - T 11-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00620 4746ceeb716c7030ff840f36b8724a98 276 Gene3D G3DSA:4.10.950.10 197 276 2.0E-37 T 11-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00620 4746ceeb716c7030ff840f36b8724a98 276 TIGRFAM TIGR01171 rplB_bact: ribosomal protein uL2 3 276 3.2E-142 T 11-10-2018 IPR005880 Ribosomal protein L2, bacterial/organellar-type GO:0003723|GO:0003735|GO:0006412|GO:0015934|GO:0016740 AFK25_00620 4746ceeb716c7030ff840f36b8724a98 276 SMART SM01382 124 253 1.6E-95 T 11-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 AFK25_00620 4746ceeb716c7030ff840f36b8724a98 276 SUPERFAMILY SSF50249 2 125 5.48E-53 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_00620 4746ceeb716c7030ff840f36b8724a98 276 Gene3D G3DSA:2.30.30.30 118 196 3.2E-36 T 11-10-2018 IPR014722 Ribosomal protein L2, domain 2 AFK25_00875 88b41074218c7a6e63a4d62d55dc5f12 306 Gene3D G3DSA:3.40.800.10 9 306 1.4E-126 T 11-10-2018 AFK25_00875 88b41074218c7a6e63a4d62d55dc5f12 306 PRINTS PR00116 Arginase signature 263 277 2.4E-42 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 AFK25_00875 88b41074218c7a6e63a4d62d55dc5f12 306 PRINTS PR00116 Arginase signature 102 117 2.4E-42 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 AFK25_00875 88b41074218c7a6e63a4d62d55dc5f12 306 PRINTS PR00116 Arginase signature 179 197 2.4E-42 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 AFK25_00875 88b41074218c7a6e63a4d62d55dc5f12 306 PRINTS PR00116 Arginase signature 125 152 2.4E-42 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 AFK25_00875 88b41074218c7a6e63a4d62d55dc5f12 306 PRINTS PR00116 Arginase signature 228 257 2.4E-42 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 AFK25_00875 88b41074218c7a6e63a4d62d55dc5f12 306 Pfam PF00491 Arginase family 10 301 3.4E-84 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 AFK25_00875 88b41074218c7a6e63a4d62d55dc5f12 306 ProSitePatterns PS01053 Arginase family signature. 231 252 - T 11-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 AFK25_00875 88b41074218c7a6e63a4d62d55dc5f12 306 SUPERFAMILY SSF52768 9 302 2.16E-98 T 11-10-2018 IPR023696 Ureohydrolase domain superfamily AFK25_00875 88b41074218c7a6e63a4d62d55dc5f12 306 TIGRFAM TIGR01229 rocF_arginase: arginase 12 305 3.2E-111 T 11-10-2018 IPR014033 Arginase GO:0004053|GO:0006525|GO:0046872 KEGG: 00220+3.5.3.1|KEGG: 00330+3.5.3.1|MetaCyc: PWY-31|MetaCyc: PWY-4984|MetaCyc: PWY-6305|MetaCyc: PWY-6922|Reactome: R-HSA-70635 AFK25_00875 88b41074218c7a6e63a4d62d55dc5f12 306 PIRSF PIRSF036979 2 302 1.7E-41 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 AFK25_03470 fd12ac2e8a55c891cd3fdd1524fcbda4 337 SUPERFAMILY SSF161098 128 319 6.02E-30 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_03470 fd12ac2e8a55c891cd3fdd1524fcbda4 337 Gene3D G3DSA:1.10.3720.10 124 336 2.9E-24 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_03470 fd12ac2e8a55c891cd3fdd1524fcbda4 337 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 31 83 9.9E-16 T 11-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain AFK25_03470 fd12ac2e8a55c891cd3fdd1524fcbda4 337 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 153 337 4.2E-32 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_01435 77c1af4291edba19a4b582f76fc80574 323 SUPERFAMILY SSF49503 118 268 1.5E-41 T 11-10-2018 IPR008972 Cupredoxin AFK25_01435 77c1af4291edba19a4b582f76fc80574 323 SUPERFAMILY SSF81464 12 111 9.16E-23 T 11-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01435 77c1af4291edba19a4b582f76fc80574 323 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 26 230 4.1E-44 T 11-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01435 77c1af4291edba19a4b582f76fc80574 323 Gene3D G3DSA:1.10.287.90 19 109 6.7E-30 T 11-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01435 77c1af4291edba19a4b582f76fc80574 323 PRINTS PR01166 Cytochrome c oxidase subunit II signature 184 201 6.1E-7 T 11-10-2018 AFK25_01435 77c1af4291edba19a4b582f76fc80574 323 PRINTS PR01166 Cytochrome c oxidase subunit II signature 91 111 6.1E-7 T 11-10-2018 AFK25_01435 77c1af4291edba19a4b582f76fc80574 323 PRINTS PR01166 Cytochrome c oxidase subunit II signature 79 91 6.1E-7 T 11-10-2018 AFK25_01435 77c1af4291edba19a4b582f76fc80574 323 PIRSF PIRSF000292 1 294 1.7E-97 T 11-10-2018 IPR006333 Cytochrome o ubiquinol oxidase subunit II GO:0016020|GO:0016682|GO:0055114 AFK25_01435 77c1af4291edba19a4b582f76fc80574 323 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 28 103 9.6E-11 T 11-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01435 77c1af4291edba19a4b582f76fc80574 323 TIGRFAM TIGR01432 QOXA: cytochrome aa3 quinol oxidase, subunit II 9 233 1.2E-88 T 11-10-2018 IPR006332 Quinol oxidase subunit II GO:0009486|GO:0016021|GO:0016682|GO:0055114 AFK25_01435 77c1af4291edba19a4b582f76fc80574 323 Gene3D G3DSA:2.60.40.420 110 272 4.3E-43 T 11-10-2018 IPR008972 Cupredoxin AFK25_00740 2d5c326839e71cf4ac15b32dd92e333e 314 Pfam PF03118 Bacterial RNA polymerase, alpha chain C terminal domain 240 305 9.5E-30 T 11-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00740 2d5c326839e71cf4ac15b32dd92e333e 314 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 56 152 1.6E-26 T 11-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00740 2d5c326839e71cf4ac15b32dd92e333e 314 Hamap MF_00059 DNA-directed RNA polymerase subunit alpha [rpoA]. 1 313 38.121 T 11-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00740 2d5c326839e71cf4ac15b32dd92e333e 314 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 26 221 5.7E-24 T 11-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00740 2d5c326839e71cf4ac15b32dd92e333e 314 Gene3D G3DSA:2.170.120.12 50 170 3.7E-92 T 11-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00740 2d5c326839e71cf4ac15b32dd92e333e 314 SUPERFAMILY SSF47789 247 313 3.4E-25 T 11-10-2018 AFK25_00740 2d5c326839e71cf4ac15b32dd92e333e 314 SUPERFAMILY SSF55257 5 230 2.35E-33 T 11-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00740 2d5c326839e71cf4ac15b32dd92e333e 314 Gene3D G3DSA:3.30.1360.10 16 221 3.7E-92 T 11-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00740 2d5c326839e71cf4ac15b32dd92e333e 314 Gene3D G3DSA:1.10.150.20 237 314 9.0E-35 T 11-10-2018 AFK25_00740 2d5c326839e71cf4ac15b32dd92e333e 314 SMART SM00662 20 227 5.7E-112 T 11-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00740 2d5c326839e71cf4ac15b32dd92e333e 314 TIGRFAM TIGR02027 rpoA: DNA-directed RNA polymerase, alpha subunit 20 313 2.0E-128 T 11-10-2018 IPR011773 DNA-directed RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00740 2d5c326839e71cf4ac15b32dd92e333e 314 SUPERFAMILY SSF56553 50 171 1.96E-45 T 11-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_00740 2d5c326839e71cf4ac15b32dd92e333e 314 ProDom PD001179 RNA POLYMERASE ALPHA DNA-DIRECTED SUBUNIT CHAIN NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION TRANSCRIPTASE 253 310 3.0E-24 T 11-10-2018 IPR011260 RNA polymerase, alpha subunit, C-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AFK25_09020 6fe798319726ea3f95f6fc27a26cffd1 225 Pfam PF02224 Cytidylate kinase 7 220 4.1E-81 T 11-10-2018 IPR011994 Cytidylate kinase domain GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 AFK25_09020 6fe798319726ea3f95f6fc27a26cffd1 225 TIGRFAM TIGR00017 cmk: cytidylate kinase 4 217 8.6E-88 T 11-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 AFK25_09020 6fe798319726ea3f95f6fc27a26cffd1 225 Hamap MF_00238 Cytidylate kinase [cmk]. 5 223 34.684 T 11-10-2018 IPR003136 Cytidylate kinase GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 AFK25_09020 6fe798319726ea3f95f6fc27a26cffd1 225 Gene3D G3DSA:3.40.50.300 1 224 8.8E-90 T 11-10-2018 AFK25_09020 6fe798319726ea3f95f6fc27a26cffd1 225 SUPERFAMILY SSF52540 4 222 1.59E-50 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_14060 6b9d40448d792cca4eb03eff83d46131 683 Gene3D G3DSA:3.40.710.10 260 667 1.9E-116 T 11-10-2018 AFK25_14060 6b9d40448d792cca4eb03eff83d46131 683 SUPERFAMILY SSF53955 50 259 6.19E-77 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily AFK25_14060 6b9d40448d792cca4eb03eff83d46131 683 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 73 606 2.4E-184 T 11-10-2018 AFK25_14060 6b9d40448d792cca4eb03eff83d46131 683 Gene3D G3DSA:1.10.3810.10 64 259 2.2E-76 T 11-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_14060 6b9d40448d792cca4eb03eff83d46131 683 Pfam PF00905 Penicillin binding protein transpeptidase domain 328 574 5.3E-30 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFK25_14060 6b9d40448d792cca4eb03eff83d46131 683 Pfam PF00912 Transglycosylase 65 237 2.5E-64 T 11-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_14060 6b9d40448d792cca4eb03eff83d46131 683 SUPERFAMILY SSF56601 219 661 3.52E-117 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFK25_07370 d6036295057838d624554230413180d4 412 SUPERFAMILY SSF53850 46 355 3.36E-41 T 11-10-2018 AFK25_07370 d6036295057838d624554230413180d4 412 Pfam PF13416 Bacterial extracellular solute-binding protein 67 346 9.2E-32 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFK25_07370 d6036295057838d624554230413180d4 412 Gene3D G3DSA:3.40.190.10 173 344 1.4E-11 T 11-10-2018 AFK25_07370 d6036295057838d624554230413180d4 412 Gene3D G3DSA:3.40.190.10 47 172 4.6E-13 T 11-10-2018 AFK25_07370 d6036295057838d624554230413180d4 412 PIRSF PIRSF029172 2 411 9.7E-139 T 11-10-2018 IPR027020 Protein ynjB AFK25_08765 947205cb2be912529453e5feb28ef25a 881 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 2 167 9.5E-26 T 11-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_08765 947205cb2be912529453e5feb28ef25a 881 SUPERFAMILY SSF53098 3 185 9.59E-53 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_08765 947205cb2be912529453e5feb28ef25a 881 Pfam PF04851 Type III restriction enzyme, res subunit 251 456 6.5E-7 T 11-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFK25_08765 947205cb2be912529453e5feb28ef25a 881 SUPERFAMILY SSF52540 266 843 4.43E-25 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_08765 947205cb2be912529453e5feb28ef25a 881 Pfam PF00929 Exonuclease 6 162 1.8E-28 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFK25_08765 947205cb2be912529453e5feb28ef25a 881 Gene3D G3DSA:3.40.50.300 251 497 6.0E-43 T 11-10-2018 AFK25_08765 947205cb2be912529453e5feb28ef25a 881 TIGRFAM TIGR01407 dinG_rel: putative DnaQ family exonuclease/DinG family helicase 4 881 5.7E-253 T 11-10-2018 IPR006310 3'-5' exonuclease DinG GO:0005524|GO:0008408 AFK25_08765 947205cb2be912529453e5feb28ef25a 881 Gene3D G3DSA:3.40.50.300 669 877 3.0E-44 T 11-10-2018 AFK25_08765 947205cb2be912529453e5feb28ef25a 881 Gene3D G3DSA:3.30.420.10 1 171 3.1E-48 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFK25_08765 947205cb2be912529453e5feb28ef25a 881 SMART SM00487 249 500 0.0064 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFK25_08765 947205cb2be912529453e5feb28ef25a 881 SMART SM00491 715 849 2.2E-36 T 11-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 AFK25_08765 947205cb2be912529453e5feb28ef25a 881 Hamap MF_02206 3'-5' exonuclease DinG [dinG]. 1 881 27.255 T 11-10-2018 IPR006310 3'-5' exonuclease DinG GO:0005524|GO:0008408 AFK25_08765 947205cb2be912529453e5feb28ef25a 881 Pfam PF13307 Helicase C-terminal domain 697 862 6.7E-42 T 11-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 AFK25_08765 947205cb2be912529453e5feb28ef25a 881 SMART SM00479 4 171 1.8E-47 T 11-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AFK25_00500 04b82300d3796f16bddcd2c8284e4e4d 465 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 3 465 40.118 T 11-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 AFK25_00500 04b82300d3796f16bddcd2c8284e4e4d 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 191 209 1.1E-29 T 11-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFK25_00500 04b82300d3796f16bddcd2c8284e4e4d 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 222 243 1.1E-29 T 11-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFK25_00500 04b82300d3796f16bddcd2c8284e4e4d 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 62 71 1.1E-29 T 11-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFK25_00500 04b82300d3796f16bddcd2c8284e4e4d 465 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 26 37 1.1E-29 T 11-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AFK25_00500 04b82300d3796f16bddcd2c8284e4e4d 465 Gene3D G3DSA:1.20.120.1910 307 465 2.4E-38 T 11-10-2018 AFK25_00500 04b82300d3796f16bddcd2c8284e4e4d 465 SUPERFAMILY SSF47323 340 464 1.83E-36 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_00500 04b82300d3796f16bddcd2c8284e4e4d 465 SUPERFAMILY SSF52374 4 312 3.22E-106 T 11-10-2018 AFK25_00500 04b82300d3796f16bddcd2c8284e4e4d 465 SMART SM00840 353 416 7.5E-18 T 11-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 AFK25_00500 04b82300d3796f16bddcd2c8284e4e4d 465 Gene3D G3DSA:3.40.50.620 1 305 2.2E-139 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_00500 04b82300d3796f16bddcd2c8284e4e4d 465 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 18 313 2.6E-139 T 11-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 AFK25_00500 04b82300d3796f16bddcd2c8284e4e4d 465 Pfam PF09190 DALR domain 353 413 7.2E-18 T 11-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 AFK25_00500 04b82300d3796f16bddcd2c8284e4e4d 465 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 4 464 1.5E-194 T 11-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 AFK25_10485 869f25062b04f53fc9747130be9de31e 257 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 250 28.524 T 11-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AFK25_10485 869f25062b04f53fc9747130be9de31e 257 SUPERFAMILY SSF51735 83 252 2.49E-44 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_10485 869f25062b04f53fc9747130be9de31e 257 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 96 170 9.3E-12 T 11-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase AFK25_10485 869f25062b04f53fc9747130be9de31e 257 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 1 70 4.1E-24 T 11-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AFK25_10485 869f25062b04f53fc9747130be9de31e 257 Gene3D G3DSA:3.40.50.10860 1 238 1.5E-91 T 11-10-2018 AFK25_10485 869f25062b04f53fc9747130be9de31e 257 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 1 252 8.2E-84 T 11-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AFK25_10485 869f25062b04f53fc9747130be9de31e 257 Gene3D G3DSA:3.40.50.720 82 218 1.5E-91 T 11-10-2018 AFK25_10485 869f25062b04f53fc9747130be9de31e 257 SUPERFAMILY SSF53223 1 82 5.12E-26 T 11-10-2018 AFK25_06155 34c77b95e39331eea1f5986c1619257f 248 Pfam PF02682 Carboxyltransferase domain, subdomain C and D 6 218 1.2E-75 T 11-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D AFK25_06155 34c77b95e39331eea1f5986c1619257f 248 Gene3D G3DSA:2.40.100.10 103 243 2.8E-61 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily AFK25_06155 34c77b95e39331eea1f5986c1619257f 248 SMART SM00796 4 218 1.5E-97 T 11-10-2018 IPR003833 Carboxyltransferase domain, subdomain C and D AFK25_06155 34c77b95e39331eea1f5986c1619257f 248 SUPERFAMILY SSF160467 6 109 6.93E-16 T 11-10-2018 AFK25_06155 34c77b95e39331eea1f5986c1619257f 248 TIGRFAM TIGR00370 TIGR00370: sensor histidine kinase inhibitor, KipI family 9 226 1.1E-73 T 11-10-2018 IPR010016 KipI family KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 AFK25_06155 34c77b95e39331eea1f5986c1619257f 248 Gene3D G3DSA:3.30.1360.40 1 98 1.7E-27 T 11-10-2018 AFK25_06155 34c77b95e39331eea1f5986c1619257f 248 SUPERFAMILY SSF50891 104 234 3.07E-50 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily AFK25_04660 6eab55bbc5d0b14b276d1238a52ca7de 571 PIRSF PIRSF000732 1 570 1.1E-230 T 11-10-2018 IPR024692 Phosphotransferase system, enzyme I GO:0008965|GO:0009401 AFK25_04660 6eab55bbc5d0b14b276d1238a52ca7de 571 Pfam PF00391 PEP-utilising enzyme, mobile domain 153 225 4.3E-24 T 11-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AFK25_04660 6eab55bbc5d0b14b276d1238a52ca7de 571 Gene3D G3DSA:3.20.20.60 234 570 8.8E-128 T 11-10-2018 AFK25_04660 6eab55bbc5d0b14b276d1238a52ca7de 571 SUPERFAMILY SSF47831 24 143 1.15E-37 T 11-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 AFK25_04660 6eab55bbc5d0b14b276d1238a52ca7de 571 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 447 462 6.0E-32 T 11-10-2018 AFK25_04660 6eab55bbc5d0b14b276d1238a52ca7de 571 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 500 512 6.0E-32 T 11-10-2018 AFK25_04660 6eab55bbc5d0b14b276d1238a52ca7de 571 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 293 312 6.0E-32 T 11-10-2018 AFK25_04660 6eab55bbc5d0b14b276d1238a52ca7de 571 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 464 479 6.0E-32 T 11-10-2018 AFK25_04660 6eab55bbc5d0b14b276d1238a52ca7de 571 Pfam PF05524 PEP-utilising enzyme, N-terminal 5 126 4.3E-34 T 11-10-2018 IPR008731 Phosphotransferase system, enzyme I N-terminal GO:0009401 AFK25_04660 6eab55bbc5d0b14b276d1238a52ca7de 571 Gene3D G3DSA:1.10.274.10 23 146 2.6E-82 T 11-10-2018 IPR036618 PtsI, HPr-binding domain superfamily GO:0009401 AFK25_04660 6eab55bbc5d0b14b276d1238a52ca7de 571 SUPERFAMILY SSF52009 125 245 4.58E-39 T 11-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 AFK25_04660 6eab55bbc5d0b14b276d1238a52ca7de 571 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 250 540 2.8E-131 T 11-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 AFK25_04660 6eab55bbc5d0b14b276d1238a52ca7de 571 Gene3D G3DSA:3.50.30.10 6 233 2.6E-82 T 11-10-2018 AFK25_04660 6eab55bbc5d0b14b276d1238a52ca7de 571 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 184 195 - T 11-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 AFK25_04660 6eab55bbc5d0b14b276d1238a52ca7de 571 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 447 465 - T 11-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 AFK25_04660 6eab55bbc5d0b14b276d1238a52ca7de 571 TIGRFAM TIGR01417 PTS_I_fam: phosphoenolpyruvate-protein phosphotransferase 4 566 4.1E-258 T 11-10-2018 IPR006318 Phosphotransferase system, enzyme I-like GO:0016772 AFK25_04660 6eab55bbc5d0b14b276d1238a52ca7de 571 SUPERFAMILY SSF51621 249 547 2.41E-114 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFK25_03475 c6c17bef99de124accb70b6a202396c1 352 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 296 1.8E-14 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFK25_03475 c6c17bef99de124accb70b6a202396c1 352 Pfam PF00005 ABC transporter 25 183 5.2E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_03475 c6c17bef99de124accb70b6a202396c1 352 Gene3D G3DSA:3.40.50.300 1 328 5.8E-104 T 11-10-2018 AFK25_03475 c6c17bef99de124accb70b6a202396c1 352 SUPERFAMILY SSF52540 4 254 1.04E-74 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_03475 c6c17bef99de124accb70b6a202396c1 352 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 233 318 8.6E-20 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFK25_03475 c6c17bef99de124accb70b6a202396c1 352 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_03475 c6c17bef99de124accb70b6a202396c1 352 SMART SM00382 33 233 1.1E-17 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_07360 b07cbbbd6204443f2ba2622b82b7cdd9 263 Gene3D G3DSA:1.10.3720.10 5 254 4.6E-38 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_07360 b07cbbbd6204443f2ba2622b82b7cdd9 263 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 253 6.0E-15 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_07360 b07cbbbd6204443f2ba2622b82b7cdd9 263 SUPERFAMILY SSF161098 7 251 5.79E-42 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_10835 f0df306d9a5af6a87fae8f64e6d0e92c 332 ProDom PD005323 DNA HELICASE HOLLIDAY JUNCTION RUVB NUCLEOTIDE-BINDING ATP-BINDING SOS RECOMBINATION RESPONSE 252 332 9.0E-29 T 11-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 AFK25_10835 f0df306d9a5af6a87fae8f64e6d0e92c 332 Gene3D G3DSA:1.10.8.60 183 257 2.8E-33 T 11-10-2018 AFK25_10835 f0df306d9a5af6a87fae8f64e6d0e92c 332 TIGRFAM TIGR00635 ruvB: Holliday junction DNA helicase RuvB 24 327 1.5E-151 T 11-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 AFK25_10835 f0df306d9a5af6a87fae8f64e6d0e92c 332 SUPERFAMILY SSF52540 21 254 6.29E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_10835 f0df306d9a5af6a87fae8f64e6d0e92c 332 Hamap MF_00016 Holliday junction ATP-dependent DNA helicase RuvB [ruvB]. 1 332 178.269 T 11-10-2018 IPR004605 DNA helicase, Holliday junction RuvB type GO:0003677|GO:0005524|GO:0006281|GO:0006310|GO:0009378 AFK25_10835 f0df306d9a5af6a87fae8f64e6d0e92c 332 Pfam PF05491 Holliday junction DNA helicase ruvB C-terminus 254 327 2.5E-35 T 11-10-2018 IPR008823 DNA helicase, Holliday junction RuvB type, C-terminal GO:0003677|GO:0006281|GO:0006310|GO:0009378 AFK25_10835 f0df306d9a5af6a87fae8f64e6d0e92c 332 SUPERFAMILY SSF46785 257 331 5.03E-26 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_10835 f0df306d9a5af6a87fae8f64e6d0e92c 332 Gene3D G3DSA:1.10.10.10 258 332 1.3E-33 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_10835 f0df306d9a5af6a87fae8f64e6d0e92c 332 Gene3D G3DSA:3.40.50.300 19 182 1.7E-40 T 11-10-2018 AFK25_10835 f0df306d9a5af6a87fae8f64e6d0e92c 332 Pfam PF05496 Holliday junction DNA helicase ruvB N-terminus 5 236 8.0E-120 T 11-10-2018 IPR008824 Holliday junction DNA helicase ruvB, N-terminal GO:0006281|GO:0006310|GO:0009378 AFK25_10835 f0df306d9a5af6a87fae8f64e6d0e92c 332 SMART SM00382 52 183 3.1E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_11515 97fb685b9282580b594610eea1844037 119 Gene3D G3DSA:1.10.720.90 2 55 3.3E-27 T 11-10-2018 AFK25_11515 97fb685b9282580b594610eea1844037 119 ProSitePatterns PS00937 Ribosomal protein L20 signature. 54 70 - T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_11515 97fb685b9282580b594610eea1844037 119 ProDom PD002389 RIBOSOMAL RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN L20 50S L20 CHLOROPLAST BACTERIAL ORGANELLE 23 72 5.0E-12 T 11-10-2018 AFK25_11515 97fb685b9282580b594610eea1844037 119 Hamap MF_00382 50S ribosomal protein L20 [rplT]. 2 115 31.035 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_11515 97fb685b9282580b594610eea1844037 119 PRINTS PR00062 Ribosomal protein L20 signature 12 41 1.2E-41 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_11515 97fb685b9282580b594610eea1844037 119 PRINTS PR00062 Ribosomal protein L20 signature 42 71 1.2E-41 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_11515 97fb685b9282580b594610eea1844037 119 PRINTS PR00062 Ribosomal protein L20 signature 75 101 1.2E-41 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_11515 97fb685b9282580b594610eea1844037 119 SUPERFAMILY SSF74731 2 116 8.11E-52 T 11-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_11515 97fb685b9282580b594610eea1844037 119 TIGRFAM TIGR01032 rplT_bact: ribosomal protein bL20 1 114 4.6E-52 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_11515 97fb685b9282580b594610eea1844037 119 Gene3D G3DSA:1.10.1900.20 56 119 1.1E-29 T 11-10-2018 IPR035566 Ribosomal protein L20, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_11515 97fb685b9282580b594610eea1844037 119 Pfam PF00453 Ribosomal protein L20 3 109 6.5E-51 T 11-10-2018 IPR005813 Ribosomal protein L20 GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_08970 ea4961295c5286fdb1724a8cf533febd 240 ProDom PD119161 YPHF BH1644 PROTEINS PRECURSOR ORF1 RBL05088 SIGNAL SIMILAR 17 237 2.0E-94 T 11-10-2018 AFK25_03365 c0c535de34437c8d4d8e5c62b81bc694 341 SUPERFAMILY SSF51735 2 169 6.92E-48 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_03365 c0c535de34437c8d4d8e5c62b81bc694 341 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 1 341 2.1E-136 T 11-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFK25_03365 c0c535de34437c8d4d8e5c62b81bc694 341 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 137 6.1E-33 T 11-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFK25_03365 c0c535de34437c8d4d8e5c62b81bc694 341 SMART SM00859 2 137 7.9E-54 T 11-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AFK25_03365 c0c535de34437c8d4d8e5c62b81bc694 341 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 154 312 2.8E-27 T 11-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFK25_03365 c0c535de34437c8d4d8e5c62b81bc694 341 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 335 43.505 T 11-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFK25_03365 c0c535de34437c8d4d8e5c62b81bc694 341 SUPERFAMILY SSF55347 145 309 3.71E-52 T 11-10-2018 AFK25_03365 c0c535de34437c8d4d8e5c62b81bc694 341 Gene3D G3DSA:3.40.50.720 2 327 1.6E-126 T 11-10-2018 AFK25_03365 c0c535de34437c8d4d8e5c62b81bc694 341 Gene3D G3DSA:3.30.360.10 143 309 1.6E-126 T 11-10-2018 AFK25_03365 c0c535de34437c8d4d8e5c62b81bc694 341 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 140 156 - T 11-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFK25_03425 a900828fe58e7a69e0fbc8c610eed2e7 310 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 219 308 6.0E-35 T 11-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFK25_03425 a900828fe58e7a69e0fbc8c610eed2e7 310 Gene3D G3DSA:3.40.47.10 1 310 7.1E-134 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_03425 a900828fe58e7a69e0fbc8c610eed2e7 310 SUPERFAMILY SSF53901 4 308 1.99E-75 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_03425 a900828fe58e7a69e0fbc8c610eed2e7 310 Hamap MF_01815 3-oxoacyl-[acyl-carrier-protein] synthase 3 [fabH]. 1 308 72.745 T 11-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFK25_03425 a900828fe58e7a69e0fbc8c610eed2e7 310 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 106 184 3.7E-31 T 11-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFK25_03425 a900828fe58e7a69e0fbc8c610eed2e7 310 TIGRFAM TIGR00747 fabH: 3-oxoacyl-[acyl-carrier-protein] synthase III 2 308 1.1E-134 T 11-10-2018 IPR004655 3-oxoacyl-[acyl-carrier-protein] synthase 3 GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AFK25_12515 91b658bae5487eb00eaed652cdeaf4a1 166 SMART SM00344 3 114 6.3E-10 T 11-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AFK25_12515 91b658bae5487eb00eaed652cdeaf4a1 166 Gene3D G3DSA:3.30.70.920 56 153 9.8E-22 T 11-10-2018 AFK25_12515 91b658bae5487eb00eaed652cdeaf4a1 166 SUPERFAMILY SSF54909 66 147 3.49E-19 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel AFK25_12515 91b658bae5487eb00eaed652cdeaf4a1 166 Pfam PF01037 Lrp/AsnC ligand binding domain 73 144 2.6E-16 T 11-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AFK25_12515 91b658bae5487eb00eaed652cdeaf4a1 166 Gene3D G3DSA:1.10.10.10 1 55 4.6E-11 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_12515 91b658bae5487eb00eaed652cdeaf4a1 166 SUPERFAMILY SSF46785 3 61 3.41E-8 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_12515 91b658bae5487eb00eaed652cdeaf4a1 166 Pfam PF13412 Winged helix-turn-helix DNA-binding 4 49 1.6E-7 T 11-10-2018 AFK25_07100 a6f5b9d8af6b44624a1158f1d1b23721 255 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 8 246 15.723 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFK25_07100 a6f5b9d8af6b44624a1158f1d1b23721 255 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 19 230 4.8E-60 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFK25_07100 a6f5b9d8af6b44624a1158f1d1b23721 255 Pfam PF00902 Sec-independent protein translocase protein (TatC) 21 225 9.5E-55 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFK25_07100 a6f5b9d8af6b44624a1158f1d1b23721 255 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 89 107 2.8E-37 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFK25_07100 a6f5b9d8af6b44624a1158f1d1b23721 255 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 107 133 2.8E-37 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFK25_07100 a6f5b9d8af6b44624a1158f1d1b23721 255 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 158 186 2.8E-37 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFK25_07100 a6f5b9d8af6b44624a1158f1d1b23721 255 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 18 45 2.8E-37 T 11-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AFK25_09085 287a89327db0be0e526ca4d644018381 252 Pfam PF00149 Calcineurin-like phosphoesterase 41 197 2.3E-12 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFK25_09085 287a89327db0be0e526ca4d644018381 252 Gene3D G3DSA:3.60.21.10 39 225 3.2E-22 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like AFK25_09085 287a89327db0be0e526ca4d644018381 252 SUPERFAMILY SSF56300 37 249 5.11E-32 T 11-10-2018 AFK25_10325 2a42b7cd8f07269a14a43b0581a3ef60 395 Pfam PF06898 Putative stage IV sporulation protein YqfD 9 385 3.3E-123 T 11-10-2018 IPR010690 Putative stage IV sporulation YqfD AFK25_10325 2a42b7cd8f07269a14a43b0581a3ef60 395 PIRSF PIRSF029895 1 395 9.2E-148 T 11-10-2018 IPR010690 Putative stage IV sporulation YqfD AFK25_10325 2a42b7cd8f07269a14a43b0581a3ef60 395 TIGRFAM TIGR02876 spore_yqfD: sporulation protein YqfD 5 386 1.7E-123 T 11-10-2018 IPR010690 Putative stage IV sporulation YqfD AFK25_12680 c6d04c729d925805b04e314a2b686855 294 Pfam PF16881 N-terminal domain of lipoyl synthase of Radical_SAM family 4 45 6.4E-11 T 11-10-2018 IPR031691 Lipoyl synthase, N-terminal KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFK25_12680 c6d04c729d925805b04e314a2b686855 294 Hamap MF_00206 Lipoyl synthase [lipA]. 1 294 149.706 T 11-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFK25_12680 c6d04c729d925805b04e314a2b686855 294 SUPERFAMILY SSF102114 21 286 2.75E-64 T 11-10-2018 AFK25_12680 c6d04c729d925805b04e314a2b686855 294 PIRSF PIRSF005963 1 294 7.3E-138 T 11-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFK25_12680 c6d04c729d925805b04e314a2b686855 294 Gene3D G3DSA:3.20.20.70 14 268 1.1E-23 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_12680 c6d04c729d925805b04e314a2b686855 294 SMART SM00729 57 265 5.4E-18 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFK25_12680 c6d04c729d925805b04e314a2b686855 294 TIGRFAM TIGR00510 lipA: lipoyl synthase 3 289 9.2E-123 T 11-10-2018 IPR003698 Lipoyl synthase GO:0009107|GO:0016992|GO:0051539 KEGG: 00785+2.8.1.8|MetaCyc: PWY-6987|MetaCyc: PWY-7382|Reactome: R-HSA-389661 AFK25_12680 c6d04c729d925805b04e314a2b686855 294 Pfam PF04055 Radical SAM superfamily 64 223 5.3E-15 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFK25_11010 c082e5a1992e5f873225994466ab53e0 171 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 10 32 4.1E-7 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_11010 c082e5a1992e5f873225994466ab53e0 171 Gene3D G3DSA:3.30.700.10 13 145 1.0E-15 T 11-10-2018 AFK25_11010 c082e5a1992e5f873225994466ab53e0 171 SUPERFAMILY SSF54523 13 108 9.42E-14 T 11-10-2018 AFK25_11010 c082e5a1992e5f873225994466ab53e0 171 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 10 30 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_11010 c082e5a1992e5f873225994466ab53e0 171 Pfam PF07963 Prokaryotic N-terminal methylation motif 7 31 1.5E-7 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_02455 67b48e276a89a7ac7344de770151d171 338 Pfam PF05954 Phage late control gene D protein (GPD) 107 323 8.6E-17 T 11-10-2018 AFK25_02455 67b48e276a89a7ac7344de770151d171 338 SUPERFAMILY SSF69279 13 183 1.94E-14 T 11-10-2018 AFK25_07995 133906dd9e7c880da5dddd71ad104cb3 98 SUPERFAMILY SSF52821 12 95 4.85E-30 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_07995 133906dd9e7c880da5dddd71ad104cb3 98 Pfam PF00581 Rhodanese-like domain 13 94 1.7E-14 T 11-10-2018 IPR001763 Rhodanese-like domain AFK25_07995 133906dd9e7c880da5dddd71ad104cb3 98 SMART SM00450 5 98 1.5E-19 T 11-10-2018 IPR001763 Rhodanese-like domain AFK25_07995 133906dd9e7c880da5dddd71ad104cb3 98 Gene3D G3DSA:3.40.250.10 3 98 1.0E-28 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_12730 c30b0443dc548d37f5d210608ed66831 406 SUPERFAMILY SSF53383 2 398 1.2E-140 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_12730 c30b0443dc548d37f5d210608ed66831 406 PIRSF PIRSF005572 20 404 1.9E-54 T 11-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 AFK25_12730 c30b0443dc548d37f5d210608ed66831 406 Gene3D G3DSA:3.90.1150.10 7 395 7.8E-187 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_12730 c30b0443dc548d37f5d210608ed66831 406 Pfam PF00266 Aminotransferase class-V 23 391 2.8E-167 T 11-10-2018 IPR000192 Aminotransferase class V domain AFK25_12730 c30b0443dc548d37f5d210608ed66831 406 Gene3D G3DSA:3.40.640.10 34 294 7.8E-187 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_12730 c30b0443dc548d37f5d210608ed66831 406 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 215 234 - T 11-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site AFK25_12730 c30b0443dc548d37f5d210608ed66831 406 TIGRFAM TIGR01979 sufS: cysteine desulfurase, SufS family 5 403 2.9E-195 T 11-10-2018 IPR010970 Cysteine desulfurase, SufS GO:0006534|GO:0030170|GO:0031071 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 AFK25_01585 f141fb5fcbff6ac9949a39b1f68dd8d1 461 SMART SM00304 173 225 1.5E-6 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_01585 f141fb5fcbff6ac9949a39b1f68dd8d1 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 411 1.0E-11 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_01585 f141fb5fcbff6ac9949a39b1f68dd8d1 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 443 456 1.0E-11 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_01585 f141fb5fcbff6ac9949a39b1f68dd8d1 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 436 1.0E-11 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_01585 f141fb5fcbff6ac9949a39b1f68dd8d1 461 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 397 1.0E-11 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_01585 f141fb5fcbff6ac9949a39b1f68dd8d1 461 SMART SM00387 346 459 2.0E-34 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_01585 f141fb5fcbff6ac9949a39b1f68dd8d1 461 Gene3D G3DSA:1.20.1480.50 149 228 1.5E-6 T 11-10-2018 AFK25_01585 f141fb5fcbff6ac9949a39b1f68dd8d1 461 SUPERFAMILY SSF55874 290 457 2.62E-38 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_01585 f141fb5fcbff6ac9949a39b1f68dd8d1 461 Gene3D G3DSA:3.30.565.10 305 461 5.1E-39 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_01585 f141fb5fcbff6ac9949a39b1f68dd8d1 461 SMART SM00388 233 300 3.8E-12 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_01585 f141fb5fcbff6ac9949a39b1f68dd8d1 461 Gene3D G3DSA:1.10.287.130 229 299 2.5E-16 T 11-10-2018 AFK25_01585 f141fb5fcbff6ac9949a39b1f68dd8d1 461 Pfam PF00672 HAMP domain 174 221 1.5E-6 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_01585 f141fb5fcbff6ac9949a39b1f68dd8d1 461 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 458 9.3E-24 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_01585 f141fb5fcbff6ac9949a39b1f68dd8d1 461 SUPERFAMILY SSF47384 217 298 3.73E-15 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFK25_01585 f141fb5fcbff6ac9949a39b1f68dd8d1 461 Pfam PF00512 His Kinase A (phospho-acceptor) domain 235 299 2.3E-11 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_11470 eaed3da6135826eed76fb2145cc0dbaa 503 PIRSF PIRSF006005 2 501 1.1E-212 T 11-10-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFK25_11470 eaed3da6135826eed76fb2145cc0dbaa 503 TIGRFAM TIGR01239 galT_2: galactose-1-phosphate uridylyltransferase 8 497 1.9E-198 T 11-10-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFK25_11470 eaed3da6135826eed76fb2145cc0dbaa 503 Pfam PF02744 Galactose-1-phosphate uridyl transferase, C-terminal domain 248 428 4.9E-29 T 11-10-2018 IPR005850 Galactose-1-phosphate uridyl transferase, C-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 AFK25_11470 eaed3da6135826eed76fb2145cc0dbaa 503 Hamap MF_00571 Galactose-1-phosphate uridylyltransferase [galT]. 1 503 242.241 T 11-10-2018 IPR000766 Galactose-1-phosphate uridyl transferase, class II GO:0005737|GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFK25_11470 eaed3da6135826eed76fb2145cc0dbaa 503 ProSitePatterns PS01163 Galactose-1-phosphate uridyl transferase family 2 signature. 261 278 - T 11-10-2018 IPR023425 Galactose-1-phosphate uridyl transferase, class II, conserved site GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527 AFK25_11470 eaed3da6135826eed76fb2145cc0dbaa 503 Pfam PF01087 Galactose-1-phosphate uridyl transferase, N-terminal domain 21 233 1.3E-35 T 11-10-2018 IPR005849 Galactose-1-phosphate uridyl transferase, N-terminal GO:0006012|GO:0008108 KEGG: 00052+2.7.7.12|KEGG: 00520+2.7.7.12|MetaCyc: PWY-6317|MetaCyc: PWY-6527|Reactome: R-HSA-5609978|Reactome: R-HSA-70370 AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 Gene3D G3DSA:3.40.50.11180 35 333 3.5E-68 T 11-10-2018 AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 SUPERFAMILY SSF143517 1009 1166 3.92E-39 T 11-10-2018 IPR037235 TRCF-like, C-terminal domain AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 SUPERFAMILY SSF52540 377 490 9.03E-23 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 Pfam PF00271 Helicase conserved C-terminal domain 827 929 6.5E-18 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 Hamap MF_00969 Transcription-repair-coupling factor [mfd]. 30 1117 29.049 T 11-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 Pfam PF00270 DEAD/DEAH box helicase 626 784 1.9E-17 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 SUPERFAMILY SSF141259 490 568 3.27E-27 T 11-10-2018 IPR036101 CarD-like/TRCF domain superfamily AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 Gene3D G3DSA:3.90.1150.50 1019 1170 9.5E-43 T 11-10-2018 IPR037235 TRCF-like, C-terminal domain AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 Gene3D G3DSA:3.40.50.300 562 801 3.2E-248 T 11-10-2018 AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 Gene3D G3DSA:2.30.30.840 503 561 3.2E-248 T 11-10-2018 AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 SMART SM00982 1023 1123 8.2E-42 T 11-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 SMART SM00487 620 810 5.5E-36 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 SUPERFAMILY SSF52540 14 369 3.72E-92 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 SUPERFAMILY SSF52540 802 1009 2.08E-49 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 SMART SM01058 499 596 1.1E-50 T 11-10-2018 IPR003711 CarD-like/TRCF domain AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 Gene3D G3DSA:3.30.2060.10 140 225 3.5E-68 T 11-10-2018 AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 Pfam PF03461 TRCF domain 1024 1115 1.5E-28 T 11-10-2018 IPR005118 Transcription-repair-coupling factor, C-terminal domain GO:0006281 AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 SUPERFAMILY SSF52540 543 803 1.74E-63 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 SMART SM00490 846 930 2.5E-20 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 Pfam PF02559 CarD-like/TRCF domain 500 595 2.8E-32 T 11-10-2018 IPR003711 CarD-like/TRCF domain AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 Gene3D G3DSA:3.40.50.300 498 1008 3.2E-248 T 11-10-2018 AFK25_00295 b80ca5ae1a4b3df06ca266d29ee548ca 1170 TIGRFAM TIGR00580 mfd: transcription-repair coupling factor 158 1097 0.0 T 11-10-2018 IPR004576 Transcription-repair coupling factor GO:0003684|GO:0005524|GO:0006281 AFK25_04790 8c6f0c27a64ff76bde800af4c8c6c096 282 SUPERFAMILY SSF56300 53 280 3.8E-36 T 11-10-2018 AFK25_04790 8c6f0c27a64ff76bde800af4c8c6c096 282 Pfam PF00149 Calcineurin-like phosphoesterase 56 168 1.2E-7 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFK25_04790 8c6f0c27a64ff76bde800af4c8c6c096 282 Gene3D G3DSA:3.60.21.10 55 236 5.8E-22 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like AFK25_11785 f83ce86a5252a9ae7c4aa4047b6d7b80 636 Gene3D G3DSA:3.40.50.12780 324 462 1.5E-35 T 11-10-2018 AFK25_11785 f83ce86a5252a9ae7c4aa4047b6d7b80 636 Pfam PF00501 AMP-binding enzyme 11 469 6.0E-94 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFK25_11785 f83ce86a5252a9ae7c4aa4047b6d7b80 636 SUPERFAMILY SSF56801 4 601 1.7E-111 T 11-10-2018 AFK25_11785 f83ce86a5252a9ae7c4aa4047b6d7b80 636 Gene3D G3DSA:3.40.50.12780 1 323 6.6E-51 T 11-10-2018 AFK25_11785 f83ce86a5252a9ae7c4aa4047b6d7b80 636 ProSitePatterns PS00455 Putative AMP-binding domain signature. 185 196 - T 11-10-2018 IPR020845 AMP-binding, conserved site AFK25_14580 b7c80708ccabc51b239d97bf46007e58 78 TIGRFAM TIGR00165 S18: ribosomal protein bS18 9 76 5.5E-38 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_14580 b7c80708ccabc51b239d97bf46007e58 78 Pfam PF01084 Ribosomal protein S18 22 72 1.6E-28 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_14580 b7c80708ccabc51b239d97bf46007e58 78 ProDom PD002239 RIBOSOMAL S18 RIBONUCLEOPROTEIN 30S RRNA-BINDING RNA-BINDING CHLOROPLAST PLASTID MITOCHONDRIAL ACETYLATION 24 76 3.0E-23 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_14580 b7c80708ccabc51b239d97bf46007e58 78 ProSitePatterns PS00057 Ribosomal protein S18 signature. 25 48 - T 11-10-2018 IPR018275 Ribosomal protein S18, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_14580 b7c80708ccabc51b239d97bf46007e58 78 PRINTS PR00974 Ribosomal protein S18 family signature 64 74 2.2E-21 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_14580 b7c80708ccabc51b239d97bf46007e58 78 PRINTS PR00974 Ribosomal protein S18 family signature 32 42 2.2E-21 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_14580 b7c80708ccabc51b239d97bf46007e58 78 PRINTS PR00974 Ribosomal protein S18 family signature 50 64 2.2E-21 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_14580 b7c80708ccabc51b239d97bf46007e58 78 PRINTS PR00974 Ribosomal protein S18 family signature 42 49 2.2E-21 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_14580 b7c80708ccabc51b239d97bf46007e58 78 Gene3D G3DSA:4.10.640.10 2 77 3.1E-31 T 11-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_14580 b7c80708ccabc51b239d97bf46007e58 78 Hamap MF_00270 30S ribosomal protein S18 [rpsR]. 6 77 22.453 T 11-10-2018 IPR001648 Ribosomal protein S18 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_14580 b7c80708ccabc51b239d97bf46007e58 78 SUPERFAMILY SSF46911 5 76 1.7E-31 T 11-10-2018 IPR036870 Ribosomal protein S18 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_11325 3b73b3903f0b3cf621c629557021d110 193 Gene3D G3DSA:1.10.10.60 1 49 4.2E-22 T 11-10-2018 AFK25_11325 3b73b3903f0b3cf621c629557021d110 193 SUPERFAMILY SSF48498 78 190 7.79E-28 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFK25_11325 3b73b3903f0b3cf621c629557021d110 193 SUPERFAMILY SSF46689 4 83 1.12E-17 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_11325 3b73b3903f0b3cf621c629557021d110 193 Pfam PF08359 YsiA-like protein, C-terminal region 58 190 1.0E-62 T 11-10-2018 IPR013570 Transcription regulator YsiA, C-terminal AFK25_11325 3b73b3903f0b3cf621c629557021d110 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 11 24 1.9E-11 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_11325 3b73b3903f0b3cf621c629557021d110 193 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 32 55 1.9E-11 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_11325 3b73b3903f0b3cf621c629557021d110 193 Gene3D G3DSA:1.10.357.10 50 191 4.0E-38 T 11-10-2018 AFK25_11325 3b73b3903f0b3cf621c629557021d110 193 Pfam PF00440 Bacterial regulatory proteins, tetR family 11 56 3.2E-17 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_07725 69fbf93118db06f8298ac89a41cb08cf 383 Pfam PF01170 Putative RNA methylase family UPF0020 162 366 3.3E-67 T 11-10-2018 IPR000241 Putative RNA methylase domain AFK25_07725 69fbf93118db06f8298ac89a41cb08cf 383 Pfam PF02926 THUMP domain 17 153 4.1E-12 T 11-10-2018 IPR004114 THUMP domain GO:0003723 AFK25_07725 69fbf93118db06f8298ac89a41cb08cf 383 SUPERFAMILY SSF53335 143 365 8.16E-42 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_07725 69fbf93118db06f8298ac89a41cb08cf 383 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 195 206 - T 11-10-2018 IPR000241 Putative RNA methylase domain AFK25_07725 69fbf93118db06f8298ac89a41cb08cf 383 SMART SM00981 57 154 7.4E-8 T 11-10-2018 IPR004114 THUMP domain GO:0003723 AFK25_07725 69fbf93118db06f8298ac89a41cb08cf 383 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 299 305 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFK25_07725 69fbf93118db06f8298ac89a41cb08cf 383 Gene3D G3DSA:3.40.50.150 160 366 6.4E-126 T 11-10-2018 AFK25_07725 69fbf93118db06f8298ac89a41cb08cf 383 Gene3D G3DSA:3.30.2130.30 8 245 6.4E-126 T 11-10-2018 AFK25_13230 7baa9ea6fdc263bd0d90a7dd0f2c97a9 147 Gene3D G3DSA:2.30.290.10 1 146 8.7E-51 T 11-10-2018 IPR024046 Flagellar assembly factor FliW domain superfamily AFK25_13230 7baa9ea6fdc263bd0d90a7dd0f2c97a9 147 Hamap MF_01185 Flagellar assembly factor FliW [fliW]. 17 141 25.698 T 11-10-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 AFK25_13230 7baa9ea6fdc263bd0d90a7dd0f2c97a9 147 Pfam PF02623 FliW protein 19 137 2.6E-38 T 11-10-2018 IPR003775 Flagellar assembly factor FliW GO:0044780 AFK25_13230 7baa9ea6fdc263bd0d90a7dd0f2c97a9 147 SUPERFAMILY SSF141457 1 141 3.01E-47 T 11-10-2018 IPR024046 Flagellar assembly factor FliW domain superfamily AFK25_12640 954f222d58b3f16fde619509afbf5954 165 PIRSF PIRSF019587 4 165 9.6E-79 T 11-10-2018 IPR026038 Putative phosphatidylglycerophosphatase AFK25_12640 954f222d58b3f16fde619509afbf5954 165 Pfam PF04608 Phosphatidylglycerophosphatase A 22 158 1.0E-19 T 11-10-2018 IPR007686 YutG/PgpA domain GO:0006629|GO:0008962 AFK25_12640 954f222d58b3f16fde619509afbf5954 165 SUPERFAMILY SSF101307 10 161 4.45E-55 T 11-10-2018 IPR036681 PgpA-like superfamily GO:0006629|GO:0008962 AFK25_12640 954f222d58b3f16fde619509afbf5954 165 Gene3D G3DSA:1.10.3760.10 2 165 8.0E-75 T 11-10-2018 AFK25_10005 26e3a99e21fd0e26ffbcb25ef941e6ba 138 Pfam PF14173 ComG operon protein 7 40 136 8.0E-25 T 11-10-2018 IPR020372 Competence operon G protein 7, ComGG AFK25_10005 26e3a99e21fd0e26ffbcb25ef941e6ba 138 ProDom PD078266 COMPETENCE COMGG LATE MACHINERY OPERON DNA THE PART PRECURSOR PROBABLY 11 136 7.0E-6 T 11-10-2018 IPR020372 Competence operon G protein 7, ComGG AFK25_13300 569f22e8e38d00e723f71d0c322a1cc8 386 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 289 378 1.1E-11 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_13300 569f22e8e38d00e723f71d0c322a1cc8 386 Pfam PF07730 Histidine kinase 180 248 2.9E-16 T 11-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFK25_13300 569f22e8e38d00e723f71d0c322a1cc8 386 Pfam PF05384 Sensor protein DegS 12 170 1.8E-58 T 11-10-2018 IPR008595 Sensor DegS GO:0007165|GO:0016301 AFK25_13300 569f22e8e38d00e723f71d0c322a1cc8 386 PIRSF PIRSF003169 1 383 1.5E-157 T 11-10-2018 IPR016381 Signal transduction histidine kinase, DegS GO:0000155|GO:0000160|GO:0004673 AFK25_13300 569f22e8e38d00e723f71d0c322a1cc8 386 SUPERFAMILY SSF55874 251 377 1.15E-20 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_13300 569f22e8e38d00e723f71d0c322a1cc8 386 Gene3D G3DSA:3.30.565.10 246 383 2.4E-31 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_13300 569f22e8e38d00e723f71d0c322a1cc8 386 SMART SM00387 286 379 2.1E-10 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_10815 9fe9f4927be60d09289369b5a91c5cb6 87 SMART SM01323 2 84 1.7E-45 T 11-10-2018 IPR003849 Preprotein translocase YajC AFK25_10815 9fe9f4927be60d09289369b5a91c5cb6 87 PRINTS PR01853 Bacterial YajC preprotein translocase signature 4 24 2.0E-16 T 11-10-2018 IPR003849 Preprotein translocase YajC AFK25_10815 9fe9f4927be60d09289369b5a91c5cb6 87 PRINTS PR01853 Bacterial YajC preprotein translocase signature 42 60 2.0E-16 T 11-10-2018 IPR003849 Preprotein translocase YajC AFK25_10815 9fe9f4927be60d09289369b5a91c5cb6 87 Pfam PF02699 Preprotein translocase subunit 6 81 2.0E-30 T 11-10-2018 IPR003849 Preprotein translocase YajC AFK25_10815 9fe9f4927be60d09289369b5a91c5cb6 87 TIGRFAM TIGR00739 yajC: preprotein translocase, YajC subunit 3 84 3.7E-32 T 11-10-2018 IPR003849 Preprotein translocase YajC AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 SUPERFAMILY SSF55666 145 236 1.37E-31 T 11-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 Pfam PF03725 3' exoribonuclease family, domain 2 460 530 2.1E-7 T 11-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 Pfam PF03725 3' exoribonuclease family, domain 2 147 210 8.0E-16 T 11-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 Pfam PF00013 KH domain 557 615 4.5E-10 T 11-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 Gene3D G3DSA:3.30.230.70 1 230 2.9E-87 T 11-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 Gene3D G3DSA:2.40.50.140 623 694 1.0E-26 T 11-10-2018 AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 Pfam PF01138 3' exoribonuclease family, domain 1 14 144 1.1E-21 T 11-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 Pfam PF01138 3' exoribonuclease family, domain 1 324 457 6.5E-19 T 11-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 Gene3D G3DSA:3.30.230.70 232 550 3.3E-123 T 11-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 SMART SM00322 553 618 7.4E-13 T 11-10-2018 IPR004087 K Homology domain GO:0003676 AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 SUPERFAMILY SSF54211 292 489 3.14E-50 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 Pfam PF00575 S1 RNA binding domain 620 691 5.9E-20 T 11-10-2018 IPR003029 S1 domain GO:0003676 AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 SUPERFAMILY SSF50249 620 697 7.86E-21 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 SUPERFAMILY SSF54211 6 144 1.37E-50 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 TIGRFAM TIGR03591 polynuc_phos: polyribonucleotide nucleotidyltransferase 12 693 0.0 T 11-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 Pfam PF03726 Polyribonucleotide nucleotidyltransferase, RNA binding domain 242 321 2.3E-15 T 11-10-2018 IPR015848 Polyribonucleotide nucleotidyltransferase, RNA-binding domain GO:0003723|GO:0006396 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 PIRSF PIRSF005499 2 702 0.0 T 11-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 SUPERFAMILY SSF54791 556 641 1.67E-24 T 11-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 SMART SM00316 621 691 3.5E-25 T 11-10-2018 IPR022967 RNA-binding domain, S1 AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 SUPERFAMILY SSF55666 451 550 2.23E-30 T 11-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 Hamap MF_01595 Polyribonucleotide nucleotidyltransferase [pnp]. 4 694 31.548 T 11-10-2018 IPR012162 Polyribonucleotide nucleotidyltransferase GO:0003723|GO:0004654|GO:0006402 KEGG: 00230+2.7.7.8|KEGG: 00240+2.7.7.8 AFK25_05920 c81dec85660e4b53b8abdb5a4c064cfd 702 Gene3D G3DSA:3.30.1370.10 551 622 4.9E-21 T 11-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AFK25_08330 ff7bfad3ebcb1f400546ebcd87f2d069 1514 Gene3D G3DSA:3.20.20.70 437 781 3.5E-137 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_08330 ff7bfad3ebcb1f400546ebcd87f2d069 1514 SUPERFAMILY SSF51395 455 1200 3.42E-266 T 11-10-2018 AFK25_08330 ff7bfad3ebcb1f400546ebcd87f2d069 1514 Gene3D G3DSA:3.60.20.10 20 436 1.1E-178 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFK25_08330 ff7bfad3ebcb1f400546ebcd87f2d069 1514 Gene3D G3DSA:3.20.20.70 782 1213 1.4E-198 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_08330 ff7bfad3ebcb1f400546ebcd87f2d069 1514 Pfam PF00310 Glutamine amidotransferases class-II 20 434 1.3E-182 T 11-10-2018 IPR017932 Glutamine amidotransferase type 2 domain AFK25_08330 ff7bfad3ebcb1f400546ebcd87f2d069 1514 Pfam PF01493 GXGXG motif 1241 1427 3.2E-83 T 11-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 AFK25_08330 ff7bfad3ebcb1f400546ebcd87f2d069 1514 SUPERFAMILY SSF69336 1210 1476 2.62E-93 T 11-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 AFK25_08330 ff7bfad3ebcb1f400546ebcd87f2d069 1514 Gene3D G3DSA:2.160.20.60 1214 1485 1.1E-108 T 11-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 AFK25_08330 ff7bfad3ebcb1f400546ebcd87f2d069 1514 SUPERFAMILY SSF56235 20 437 4.4E-152 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFK25_08330 ff7bfad3ebcb1f400546ebcd87f2d069 1514 Pfam PF01645 Conserved region in glutamate synthase 795 1163 4.8E-161 T 11-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 AFK25_08330 ff7bfad3ebcb1f400546ebcd87f2d069 1514 Pfam PF04898 Glutamate synthase central domain 460 736 2.7E-118 T 11-10-2018 IPR006982 Glutamate synthase, central-N GO:0006807|GO:0015930|GO:0055114 AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 Pfam PF00009 Elongation factor Tu GTP binding domain 9 280 1.3E-70 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 Pfam PF03144 Elongation factor Tu domain 2 322 389 1.4E-16 T 11-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 Gene3D G3DSA:2.40.30.10 292 403 9.0E-48 T 11-10-2018 AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 Gene3D G3DSA:3.30.70.240 602 672 4.9E-98 T 11-10-2018 AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 Pfam PF14492 Elongation Factor G, domain II 402 475 1.8E-35 T 11-10-2018 AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 Pfam PF00679 Elongation factor G C-terminus 598 684 4.8E-33 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 Hamap MF_00054_B Elongation factor G [fusA]. 6 689 116.231 T 11-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 Gene3D G3DSA:3.40.50.300 1 291 1.4E-117 T 11-10-2018 AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 SMART SM00889 478 596 2.6E-76 T 11-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 SUPERFAMILY SSF50447 263 402 1.92E-36 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 SMART SM00838 598 685 2.1E-60 T 11-10-2018 IPR000640 Elongation factor EFG, domain V-like AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 SUPERFAMILY SSF54980 598 688 2.73E-32 T 11-10-2018 IPR035647 EF-G domain III/V-like AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 SUPERFAMILY SSF54980 400 478 7.55E-26 T 11-10-2018 IPR035647 EF-G domain III/V-like AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 9 180 2.3E-43 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 SUPERFAMILY SSF54211 477 597 6.32E-46 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 Gene3D G3DSA:3.30.230.10 482 685 4.9E-98 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 Pfam PF03764 Elongation factor G, domain IV 477 595 1.7E-49 T 11-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 SUPERFAMILY SSF52540 6 280 9.5E-115 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 TIGRFAM TIGR00484 EF-G: translation elongation factor G 1 690 0.0 T 11-10-2018 IPR004540 Translation elongation factor EFG/EF2 GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 PRINTS PR00315 GTP-binding elongation factor signature 78 88 4.7E-17 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 PRINTS PR00315 GTP-binding elongation factor signature 94 105 4.7E-17 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 PRINTS PR00315 GTP-binding elongation factor signature 130 139 4.7E-17 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 PRINTS PR00315 GTP-binding elongation factor signature 12 25 4.7E-17 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 PRINTS PR00315 GTP-binding elongation factor signature 58 66 4.7E-17 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_00590 5ec740eda673a0e09dc9bd5f6c9339ad 692 Gene3D G3DSA:3.30.70.870 404 481 5.3E-33 T 11-10-2018 AFK25_09065 74caefc50abff84dbf395b4e54be1dac 421 SMART SM00839 190 419 2.4E-98 T 11-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFK25_09065 74caefc50abff84dbf395b4e54be1dac 421 Gene3D G3DSA:1.10.8.1210 21 349 6.0E-145 T 11-10-2018 AFK25_09065 74caefc50abff84dbf395b4e54be1dac 421 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 107 120 - T 11-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFK25_09065 74caefc50abff84dbf395b4e54be1dac 421 SUPERFAMILY SSF51735 188 420 1.38E-80 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_09065 74caefc50abff84dbf395b4e54be1dac 421 PIRSF PIRSF000185 3 421 2.9E-175 T 11-10-2018 IPR014362 Glutamate dehydrogenase GO:0016639|GO:0055114 AFK25_09065 74caefc50abff84dbf395b4e54be1dac 421 SUPERFAMILY SSF53223 12 190 4.16E-66 T 11-10-2018 AFK25_09065 74caefc50abff84dbf395b4e54be1dac 421 Gene3D G3DSA:3.40.50.10860 40 175 6.0E-145 T 11-10-2018 AFK25_09065 74caefc50abff84dbf395b4e54be1dac 421 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 188 419 2.5E-81 T 11-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFK25_09065 74caefc50abff84dbf395b4e54be1dac 421 Gene3D G3DSA:3.40.50.720 176 348 6.0E-145 T 11-10-2018 AFK25_09065 74caefc50abff84dbf395b4e54be1dac 421 Gene3D G3DSA:1.10.8.1210 375 421 6.1E-20 T 11-10-2018 AFK25_09065 74caefc50abff84dbf395b4e54be1dac 421 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 43 170 3.4E-54 T 11-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFK25_09065 74caefc50abff84dbf395b4e54be1dac 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 99 113 9.4E-31 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFK25_09065 74caefc50abff84dbf395b4e54be1dac 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 347 358 9.4E-31 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFK25_09065 74caefc50abff84dbf395b4e54be1dac 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 179 201 9.4E-31 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFK25_09065 74caefc50abff84dbf395b4e54be1dac 421 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 221 241 9.4E-31 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFK25_06880 29df3393402f3facb9ecdce011745abf 76 Hamap MF_01103 UPF0291 protein . 2 60 15.399 T 11-10-2018 IPR009242 Protein of unknown function DUF896 AFK25_06880 29df3393402f3facb9ecdce011745abf 76 SUPERFAMILY SSF158221 1 42 2.35E-13 T 11-10-2018 AFK25_06880 29df3393402f3facb9ecdce011745abf 76 Pfam PF05979 Bacterial protein of unknown function (DUF896) 5 68 1.4E-30 T 11-10-2018 IPR009242 Protein of unknown function DUF896 AFK25_06880 29df3393402f3facb9ecdce011745abf 76 Gene3D G3DSA:1.10.287.540 1 56 5.3E-22 T 11-10-2018 AFK25_11315 acdae20454bbd573a8ef0d16e5fe9a57 257 SUPERFAMILY SSF52402 1 245 6.09E-80 T 11-10-2018 AFK25_11315 acdae20454bbd573a8ef0d16e5fe9a57 257 PIRSF PIRSF000090 1 257 1.4E-81 T 11-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 AFK25_11315 acdae20454bbd573a8ef0d16e5fe9a57 257 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 155 175 - T 11-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 AFK25_11315 acdae20454bbd573a8ef0d16e5fe9a57 257 Gene3D G3DSA:3.40.50.620 1 256 8.1E-87 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_11315 acdae20454bbd573a8ef0d16e5fe9a57 257 SMART SM00893 21 211 1.7E-63 T 11-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFK25_11315 acdae20454bbd573a8ef0d16e5fe9a57 257 Pfam PF01012 Electron transfer flavoprotein domain 23 206 1.4E-51 T 11-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFK25_10605 6f192ad3dbe2296e20c2e7f24c185dd3 377 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 187 201 - T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFK25_10605 6f192ad3dbe2296e20c2e7f24c185dd3 377 SUPERFAMILY SSF53383 6 376 7.93E-123 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_10605 6f192ad3dbe2296e20c2e7f24c185dd3 377 PIRSF PIRSF001434 1 377 2.0E-151 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFK25_10605 6f192ad3dbe2296e20c2e7f24c185dd3 377 Gene3D G3DSA:3.90.1150.10 246 377 8.2E-58 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_10605 6f192ad3dbe2296e20c2e7f24c185dd3 377 Gene3D G3DSA:3.40.640.10 3 245 1.2E-93 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_10605 6f192ad3dbe2296e20c2e7f24c185dd3 377 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 376 4.3E-161 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFK25_00085 0d93fc11f1bad8eadcda7dffaa17cbcb 192 Pfam PF01174 SNO glutamine amidotransferase family 6 188 2.1E-76 T 11-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFK25_00085 0d93fc11f1bad8eadcda7dffaa17cbcb 192 Gene3D G3DSA:3.40.50.880 1 192 3.2E-73 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_00085 0d93fc11f1bad8eadcda7dffaa17cbcb 192 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 3 185 4.5E-89 T 11-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFK25_00085 0d93fc11f1bad8eadcda7dffaa17cbcb 192 ProSitePatterns PS01236 PdxT/SNO family family signature. 41 51 - T 11-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFK25_00085 0d93fc11f1bad8eadcda7dffaa17cbcb 192 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 4 186 38.319 T 11-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFK25_00085 0d93fc11f1bad8eadcda7dffaa17cbcb 192 SUPERFAMILY SSF52317 3 190 2.36E-55 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_00085 0d93fc11f1bad8eadcda7dffaa17cbcb 192 PIRSF PIRSF005639 1 191 2.4E-75 T 11-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFK25_11165 abc15df1827f7e8e9ba2f217961af645 471 Pfam PF00330 Aconitase family (aconitate hydratase) 8 457 8.6E-164 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFK25_11165 abc15df1827f7e8e9ba2f217961af645 471 ProSitePatterns PS01244 Aconitase family signature 2. 399 412 - T 11-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFK25_11165 abc15df1827f7e8e9ba2f217961af645 471 Gene3D G3DSA:3.30.499.10 323 471 2.4E-51 T 11-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 AFK25_11165 abc15df1827f7e8e9ba2f217961af645 471 Hamap MF_01026 3-isopropylmalate dehydratase large subunit [leuC]. 2 466 60.36 T 11-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AFK25_11165 abc15df1827f7e8e9ba2f217961af645 471 Gene3D G3DSA:3.30.499.20 5 286 1.8E-104 T 11-10-2018 AFK25_11165 abc15df1827f7e8e9ba2f217961af645 471 ProSitePatterns PS00450 Aconitase family signature 1. 339 355 - T 11-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AFK25_11165 abc15df1827f7e8e9ba2f217961af645 471 PRINTS PR00415 Aconitase family signature 209 222 4.6E-47 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFK25_11165 abc15df1827f7e8e9ba2f217961af645 471 PRINTS PR00415 Aconitase family signature 82 95 4.6E-47 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFK25_11165 abc15df1827f7e8e9ba2f217961af645 471 PRINTS PR00415 Aconitase family signature 133 148 4.6E-47 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFK25_11165 abc15df1827f7e8e9ba2f217961af645 471 PRINTS PR00415 Aconitase family signature 286 300 4.6E-47 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFK25_11165 abc15df1827f7e8e9ba2f217961af645 471 PRINTS PR00415 Aconitase family signature 343 354 4.6E-47 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFK25_11165 abc15df1827f7e8e9ba2f217961af645 471 PRINTS PR00415 Aconitase family signature 108 116 4.6E-47 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFK25_11165 abc15df1827f7e8e9ba2f217961af645 471 PRINTS PR00415 Aconitase family signature 119 132 4.6E-47 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFK25_11165 abc15df1827f7e8e9ba2f217961af645 471 PRINTS PR00415 Aconitase family signature 195 208 4.6E-47 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFK25_11165 abc15df1827f7e8e9ba2f217961af645 471 PRINTS PR00415 Aconitase family signature 399 412 4.6E-47 T 11-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AFK25_11165 abc15df1827f7e8e9ba2f217961af645 471 TIGRFAM TIGR00170 leuC: 3-isopropylmalate dehydratase, large subunit 3 464 2.4E-249 T 11-10-2018 IPR004430 3-isopropylmalate dehydratase, large subunit GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AFK25_11165 abc15df1827f7e8e9ba2f217961af645 471 SUPERFAMILY SSF53732 2 465 1.31E-174 T 11-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 AFK25_03360 499f5265b89a0f2def5b9f170ef25873 227 SUPERFAMILY SSF51206 16 133 8.38E-27 T 11-10-2018 IPR018490 Cyclic nucleotide-binding-like AFK25_03360 499f5265b89a0f2def5b9f170ef25873 227 Gene3D G3DSA:2.60.120.10 2 135 1.8E-26 T 11-10-2018 IPR014710 RmlC-like jelly roll fold AFK25_03360 499f5265b89a0f2def5b9f170ef25873 227 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 180 195 1.6E-6 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFK25_03360 499f5265b89a0f2def5b9f170ef25873 227 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 164 180 1.6E-6 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFK25_03360 499f5265b89a0f2def5b9f170ef25873 227 SMART SM00419 158 206 5.5E-14 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFK25_03360 499f5265b89a0f2def5b9f170ef25873 227 SUPERFAMILY SSF46785 137 223 2.63E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_03360 499f5265b89a0f2def5b9f170ef25873 227 SMART SM00100 2 119 3.4E-16 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain AFK25_03360 499f5265b89a0f2def5b9f170ef25873 227 Gene3D G3DSA:1.10.10.10 136 219 8.7E-29 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_03360 499f5265b89a0f2def5b9f170ef25873 227 Pfam PF13545 Crp-like helix-turn-helix domain 140 212 1.0E-16 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFK25_03360 499f5265b89a0f2def5b9f170ef25873 227 Pfam PF00027 Cyclic nucleotide-binding domain 22 104 2.2E-16 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain AFK25_06510 142fc3389c3a18fc28b86272f5db9cc1 416 SMART SM00387 304 415 7.9E-21 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_06510 142fc3389c3a18fc28b86272f5db9cc1 416 Gene3D G3DSA:3.30.565.10 265 415 7.5E-28 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_06510 142fc3389c3a18fc28b86272f5db9cc1 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 375 393 5.6E-8 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_06510 142fc3389c3a18fc28b86272f5db9cc1 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 412 5.6E-8 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_06510 142fc3389c3a18fc28b86272f5db9cc1 416 PRINTS PR00344 Bacterial sensor protein C-terminal signature 341 355 5.6E-8 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_06510 142fc3389c3a18fc28b86272f5db9cc1 416 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 309 414 3.1E-17 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_06510 142fc3389c3a18fc28b86272f5db9cc1 416 SUPERFAMILY SSF55874 268 412 6.81E-30 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_04380 340c6e1df82693253c22814cb04c9ca2 344 Gene3D G3DSA:3.40.50.10470 142 342 9.5E-68 T 11-10-2018 AFK25_04380 340c6e1df82693253c22814cb04c9ca2 344 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 29 327 1.4E-129 T 11-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AFK25_04380 340c6e1df82693253c22814cb04c9ca2 344 SUPERFAMILY SSF100950 2 332 6.84E-119 T 11-10-2018 IPR037171 NagB/RpiA transferase-like AFK25_04380 340c6e1df82693253c22814cb04c9ca2 344 Pfam PF01008 Initiation factor 2 subunit family 42 327 1.2E-91 T 11-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 AFK25_04380 340c6e1df82693253c22814cb04c9ca2 344 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 3 339 38.962 T 11-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AFK25_04380 340c6e1df82693253c22814cb04c9ca2 344 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 2 327 1.6E-140 T 11-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AFK25_04380 340c6e1df82693253c22814cb04c9ca2 344 Gene3D G3DSA:1.20.120.420 1 141 1.3E-52 T 11-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AFK25_08915 fa6cea67767f9c4dd7c36ee38127dbbe 379 SUPERFAMILY SSF56796 6 356 1.11E-103 T 11-10-2018 AFK25_08915 fa6cea67767f9c4dd7c36ee38127dbbe 379 PIRSF PIRSF001455 4 363 1.5E-108 T 11-10-2018 IPR030963 3-dehydroquinate synthase family GO:0009073|GO:0016838 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 AFK25_08915 fa6cea67767f9c4dd7c36ee38127dbbe 379 Gene3D G3DSA:1.20.1090.10 175 360 3.0E-57 T 11-10-2018 AFK25_08915 fa6cea67767f9c4dd7c36ee38127dbbe 379 Pfam PF01761 3-dehydroquinate synthase 71 326 1.6E-99 T 11-10-2018 IPR030960 3-dehydroquinate synthase domain KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 AFK25_08915 fa6cea67767f9c4dd7c36ee38127dbbe 379 TIGRFAM TIGR01357 aroB: 3-dehydroquinate synthase 14 354 1.1E-118 T 11-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 AFK25_08915 fa6cea67767f9c4dd7c36ee38127dbbe 379 Hamap MF_00110 3-dehydroquinate synthase [aroB]. 2 362 66.14 T 11-10-2018 IPR016037 3-dehydroquinate synthase AroB GO:0003856|GO:0005737|GO:0009073 KEGG: 00400+4.2.3.4|MetaCyc: PWY-6164 AFK25_08915 fa6cea67767f9c4dd7c36ee38127dbbe 379 Gene3D G3DSA:3.40.50.1970 1 174 1.5E-63 T 11-10-2018 AFK25_01835 78a501cfd3ef1d69198ab7e460d34191 480 Hamap MF_00692 UPF0061 protein YdiU [ydiU]. 3 466 45.645 T 11-10-2018 IPR003846 Uncharacterised protein family UPF0061 AFK25_01835 78a501cfd3ef1d69198ab7e460d34191 480 Pfam PF02696 Uncharacterized ACR, YdiU/UPF0061 family 5 449 9.1E-119 T 11-10-2018 IPR003846 Uncharacterised protein family UPF0061 AFK25_00305 377fbdb330f368feeb636a03da9bb88d 518 Pfam PF01943 Polysaccharide biosynthesis protein 7 301 3.8E-40 T 11-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 AFK25_00305 377fbdb330f368feeb636a03da9bb88d 518 PIRSF PIRSF038958 1 509 3.5E-77 T 11-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type AFK25_00305 377fbdb330f368feeb636a03da9bb88d 518 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 348 491 3.9E-27 T 11-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain AFK25_05965 227ef4aea813935650b57149c6a3beb8 553 Hamap MF_01491 Ribonuclease J [rnj]. 2 553 45.89 T 11-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 AFK25_05965 227ef4aea813935650b57149c6a3beb8 553 SMART SM00849 19 214 4.7E-19 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_05965 227ef4aea813935650b57149c6a3beb8 553 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 7 551 5.8E-205 T 11-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 AFK25_05965 227ef4aea813935650b57149c6a3beb8 553 Gene3D G3DSA:3.60.15.10 10 440 4.7E-178 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_05965 227ef4aea813935650b57149c6a3beb8 553 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 362 390 - T 11-10-2018 IPR001587 Ribonuclease J, conserved site AFK25_05965 227ef4aea813935650b57149c6a3beb8 553 PIRSF PIRSF004803 1 553 1.6E-226 T 11-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 AFK25_05965 227ef4aea813935650b57149c6a3beb8 553 Pfam PF00753 Metallo-beta-lactamase superfamily 16 165 2.8E-15 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_05965 227ef4aea813935650b57149c6a3beb8 553 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 359 399 1.0E-10 T 11-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain AFK25_05965 227ef4aea813935650b57149c6a3beb8 553 Gene3D G3DSA:3.40.50.10710 206 356 4.7E-178 T 11-10-2018 AFK25_05965 227ef4aea813935650b57149c6a3beb8 553 Gene3D G3DSA:3.10.20.580 447 553 3.1E-38 T 11-10-2018 AFK25_05965 227ef4aea813935650b57149c6a3beb8 553 SUPERFAMILY SSF56281 7 422 2.92E-90 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_02535 292a966e8dd3e5f78a19e02f15a51fc3 87 Pfam PF01381 Helix-turn-helix 24 78 6.1E-9 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFK25_02535 292a966e8dd3e5f78a19e02f15a51fc3 87 SUPERFAMILY SSF47413 19 84 1.56E-12 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFK25_02535 292a966e8dd3e5f78a19e02f15a51fc3 87 SMART SM00530 23 78 3.2E-7 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFK25_02535 292a966e8dd3e5f78a19e02f15a51fc3 87 Gene3D G3DSA:1.10.260.40 14 83 4.2E-17 T 11-10-2018 AFK25_03535 deed83bc17e4a7e79ec79e121d49d128 196 SUPERFAMILY SSF55154 5 188 1.1E-28 T 11-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 AFK25_03535 deed83bc17e4a7e79ec79e121d49d128 196 PIRSF PIRSF012526 1 193 1.1E-65 T 11-10-2018 IPR009195 Uncharacterised protein family YjbK AFK25_03535 deed83bc17e4a7e79ec79e121d49d128 196 Pfam PF01928 CYTH domain 5 186 3.0E-28 T 11-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 AFK25_03535 deed83bc17e4a7e79ec79e121d49d128 196 Gene3D G3DSA:2.40.320.10 1 191 1.8E-49 T 11-10-2018 AFK25_03535 deed83bc17e4a7e79ec79e121d49d128 196 SMART SM01118 4 189 3.7E-20 T 11-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 AFK25_02260 d73115c11cca197a96403508c9006fe8 75 Pfam PF01381 Helix-turn-helix 6 58 4.5E-13 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFK25_02260 d73115c11cca197a96403508c9006fe8 75 SMART SM00530 5 60 4.9E-11 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFK25_02260 d73115c11cca197a96403508c9006fe8 75 Gene3D G3DSA:1.10.260.40 2 73 3.4E-17 T 11-10-2018 AFK25_02260 d73115c11cca197a96403508c9006fe8 75 SUPERFAMILY SSF47413 4 65 2.41E-16 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFK25_08790 731b07c69fe34bac67b007c09cfb9dea 397 Gene3D G3DSA:1.10.110.30 145 240 9.8E-31 T 11-10-2018 AFK25_08790 731b07c69fe34bac67b007c09cfb9dea 397 Pfam PF13735 tRNA nucleotidyltransferase domain 2 putative 246 387 3.4E-28 T 11-10-2018 IPR032810 CCA-adding enzyme, C-terminal AFK25_08790 731b07c69fe34bac67b007c09cfb9dea 397 SUPERFAMILY SSF81891 141 391 2.35E-47 T 11-10-2018 AFK25_08790 731b07c69fe34bac67b007c09cfb9dea 397 Gene3D G3DSA:1.10.246.80 335 397 1.2E-22 T 11-10-2018 AFK25_08790 731b07c69fe34bac67b007c09cfb9dea 397 Pfam PF01743 Poly A polymerase head domain 22 141 9.4E-35 T 11-10-2018 IPR002646 Poly A polymerase, head domain GO:0003723|GO:0006396|GO:0016779 Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 AFK25_08790 731b07c69fe34bac67b007c09cfb9dea 397 Gene3D G3DSA:1.20.58.560 243 334 2.2E-11 T 11-10-2018 AFK25_08790 731b07c69fe34bac67b007c09cfb9dea 397 SUPERFAMILY SSF81301 4 139 4.58E-42 T 11-10-2018 AFK25_08790 731b07c69fe34bac67b007c09cfb9dea 397 Gene3D G3DSA:3.30.460.10 2 144 2.0E-53 T 11-10-2018 AFK25_08790 731b07c69fe34bac67b007c09cfb9dea 397 Hamap MF_01263 CCA-adding enzyme [cca]. 2 391 39.41 T 11-10-2018 IPR023068 CCA-adding enzyme, firmicutes GO:0001680|GO:0004810|GO:0016437 AFK25_08790 731b07c69fe34bac67b007c09cfb9dea 397 Pfam PF12627 Probable RNA and SrmB- binding site of polymerase A 169 228 2.0E-16 T 11-10-2018 IPR032828 tRNA nucleotidyltransferase/poly(A) polymerase, RNA and SrmB- binding domain Reactome: R-HSA-6784531|Reactome: R-HSA-6785470 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 Pfam PF00141 Peroxidase 394 693 2.4E-36 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 Pfam PF00141 Peroxidase 64 386 1.7E-53 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 SUPERFAMILY SSF48113 427 718 5.75E-109 T 11-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 Gene3D G3DSA:1.10.520.10 16 422 5.3E-220 T 11-10-2018 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 47 60 1.8E-58 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 471 497 1.8E-58 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 62 87 1.8E-58 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 21 43 1.8E-58 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 257 280 1.8E-58 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 ProSitePatterns PS00436 Peroxidases active site signature. 85 96 - T 11-10-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 Gene3D G3DSA:1.10.520.10 423 718 6.4E-149 T 11-10-2018 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 Gene3D G3DSA:1.10.420.10 573 694 6.4E-149 T 11-10-2018 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 SUPERFAMILY SSF48113 14 421 7.07E-165 T 11-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 249 259 - T 11-10-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 9 719 0.0 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 Hamap MF_01961 Catalase-peroxidase [katG]. 7 719 41.834 T 11-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 PRINTS PR00458 Haem peroxidase superfamily signature 163 175 7.1E-23 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 PRINTS PR00458 Haem peroxidase superfamily signature 85 99 7.1E-23 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 PRINTS PR00458 Haem peroxidase superfamily signature 249 264 7.1E-23 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 PRINTS PR00458 Haem peroxidase superfamily signature 308 323 7.1E-23 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 PRINTS PR00458 Haem peroxidase superfamily signature 145 162 7.1E-23 T 11-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AFK25_08500 0e57d02500d18bedb81bda00ddcc4422 728 Gene3D G3DSA:1.10.420.20 186 389 5.3E-220 T 11-10-2018 AFK25_06355 8d8bae5f5f2d8a8cff45c320db20638d 573 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 432 562 0.0084 T 11-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFK25_06355 8d8bae5f5f2d8a8cff45c320db20638d 573 SUPERFAMILY SSF56014 148 346 3.66E-60 T 11-10-2018 AFK25_06355 8d8bae5f5f2d8a8cff45c320db20638d 573 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 172 332 1.8E-47 T 11-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFK25_06355 8d8bae5f5f2d8a8cff45c320db20638d 573 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 481 497 - T 11-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFK25_06355 8d8bae5f5f2d8a8cff45c320db20638d 573 Gene3D G3DSA:3.30.413.10 429 570 1.1E-36 T 11-10-2018 AFK25_06355 8d8bae5f5f2d8a8cff45c320db20638d 573 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 356 420 4.0E-16 T 11-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFK25_06355 8d8bae5f5f2d8a8cff45c320db20638d 573 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 77 139 4.6E-16 T 11-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFK25_06355 8d8bae5f5f2d8a8cff45c320db20638d 573 PRINTS PR00397 Sirohaem Fe-binding site signature 433 451 2.4E-7 T 11-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFK25_06355 8d8bae5f5f2d8a8cff45c320db20638d 573 PRINTS PR00397 Sirohaem Fe-binding site signature 481 499 2.4E-7 T 11-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFK25_06355 8d8bae5f5f2d8a8cff45c320db20638d 573 SUPERFAMILY SSF56014 431 563 2.62E-34 T 11-10-2018 AFK25_06355 8d8bae5f5f2d8a8cff45c320db20638d 573 Gene3D G3DSA:3.30.413.10 202 339 8.2E-47 T 11-10-2018 AFK25_06355 8d8bae5f5f2d8a8cff45c320db20638d 573 SUPERFAMILY SSF55124 348 424 1.8E-22 T 11-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFK25_06355 8d8bae5f5f2d8a8cff45c320db20638d 573 SUPERFAMILY SSF55124 15 147 1.46E-33 T 11-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFK25_06355 8d8bae5f5f2d8a8cff45c320db20638d 573 Hamap MF_01540 Sulfite reductase [NADPH] hemoprotein beta-component [cysI]. 10 573 59.653 T 11-10-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFK25_06355 8d8bae5f5f2d8a8cff45c320db20638d 573 Gene3D G3DSA:3.90.480.10 81 173 3.2E-26 T 11-10-2018 AFK25_06355 8d8bae5f5f2d8a8cff45c320db20638d 573 Gene3D G3DSA:3.90.480.10 340 425 2.2E-32 T 11-10-2018 AFK25_06355 8d8bae5f5f2d8a8cff45c320db20638d 573 TIGRFAM TIGR02041 CysI: sulfite reductase (NADPH) hemoprotein, beta-component 19 562 5.6E-283 T 11-10-2018 IPR011786 Sulphite reductase (NADPH) hemoprotein, beta subunit GO:0004783|GO:0008652|GO:0009337|GO:0050661|GO:0051539 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AFK25_10595 4a506339e4666dd3ff8ae6f6519e641b 207 ProSitePatterns PS01284 Thermonuclease family signature 2. 149 159 - T 11-10-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 AFK25_10595 4a506339e4666dd3ff8ae6f6519e641b 207 SMART SM00318 75 207 3.7E-42 T 11-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 AFK25_10595 4a506339e4666dd3ff8ae6f6519e641b 207 Gene3D G3DSA:2.40.50.90 70 207 2.0E-52 T 11-10-2018 IPR035437 SNase-like, OB-fold superfamily AFK25_10595 4a506339e4666dd3ff8ae6f6519e641b 207 SUPERFAMILY SSF50199 74 206 9.42E-38 T 11-10-2018 AFK25_10595 4a506339e4666dd3ff8ae6f6519e641b 207 Pfam PF00565 Staphylococcal nuclease homologue 101 206 1.4E-32 T 11-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 AFK25_08810 d05e7c5d0f05f7f5ab67677fe802c42d 264 SUPERFAMILY SSF55347 127 235 1.11E-39 T 11-10-2018 AFK25_08810 d05e7c5d0f05f7f5ab67677fe802c42d 264 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 263 2.0E-88 T 11-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFK25_08810 d05e7c5d0f05f7f5ab67677fe802c42d 264 PIRSF PIRSF000161 1 264 9.7E-71 T 11-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFK25_08810 d05e7c5d0f05f7f5ab67677fe802c42d 264 Gene3D G3DSA:3.30.360.10 128 233 3.3E-78 T 11-10-2018 AFK25_08810 d05e7c5d0f05f7f5ab67677fe802c42d 264 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 148 165 - T 11-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFK25_08810 d05e7c5d0f05f7f5ab67677fe802c42d 264 Gene3D G3DSA:3.40.50.720 3 260 3.3E-78 T 11-10-2018 AFK25_08810 d05e7c5d0f05f7f5ab67677fe802c42d 264 SUPERFAMILY SSF51735 1 153 2.3E-40 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_08810 d05e7c5d0f05f7f5ab67677fe802c42d 264 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 129 262 9.9E-33 T 11-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFK25_08810 d05e7c5d0f05f7f5ab67677fe802c42d 264 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 2 264 30.803 T 11-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFK25_08810 d05e7c5d0f05f7f5ab67677fe802c42d 264 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 2 126 8.2E-35 T 11-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFK25_05825 70b3086dec2a59503599baf1526f646a 293 TIGRFAM TIGR00116 tsf: translation elongation factor Ts 1 292 2.0E-124 T 11-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFK25_05825 70b3086dec2a59503599baf1526f646a 293 Gene3D G3DSA:1.10.286.20 199 236 2.6E-20 T 11-10-2018 AFK25_05825 70b3086dec2a59503599baf1526f646a 293 ProSitePatterns PS01126 Elongation factor Ts signature 1. 11 26 - T 11-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFK25_05825 70b3086dec2a59503599baf1526f646a 293 Hamap MF_00050 Elongation factor Ts [tsf]. 1 291 86.06 T 11-10-2018 IPR001816 Translation elongation factor EFTs/EF1B GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFK25_05825 70b3086dec2a59503599baf1526f646a 293 SUPERFAMILY SSF46934 1 55 2.81E-22 T 11-10-2018 IPR009060 UBA-like superfamily GO:0005515 AFK25_05825 70b3086dec2a59503599baf1526f646a 293 Gene3D G3DSA:1.10.8.10 1 55 2.1E-29 T 11-10-2018 AFK25_05825 70b3086dec2a59503599baf1526f646a 293 SUPERFAMILY SSF54713 151 292 1.13E-53 T 11-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 AFK25_05825 70b3086dec2a59503599baf1526f646a 293 SUPERFAMILY SSF54713 55 145 4.71E-24 T 11-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 AFK25_05825 70b3086dec2a59503599baf1526f646a 293 ProSitePatterns PS01127 Elongation factor Ts signature 2. 74 84 - T 11-10-2018 IPR018101 Translation elongation factor Ts, conserved site GO:0003746|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFK25_05825 70b3086dec2a59503599baf1526f646a 293 Gene3D G3DSA:3.30.479.20 56 147 2.6E-26 T 11-10-2018 IPR036402 Elongation factor Ts, dimerisation domain superfamily Reactome: R-HSA-5389840 AFK25_05825 70b3086dec2a59503599baf1526f646a 293 Pfam PF00889 Elongation factor TS 70 274 2.1E-78 T 11-10-2018 IPR014039 Translation elongation factor EFTs/EF1B, dimerisation GO:0003746|GO:0006414 Reactome: R-HSA-5389840 AFK25_09260 89c3896b6ac5e58745e08d49b8b54aa8 258 SUPERFAMILY SSF54719 139 253 1.83E-42 T 11-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_09260 89c3896b6ac5e58745e08d49b8b54aa8 258 PIRSF PIRSF000349 34 257 5.5E-88 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_09260 89c3896b6ac5e58745e08d49b8b54aa8 258 Pfam PF02777 Iron/manganese superoxide dismutases, C-terminal domain 147 249 9.5E-37 T 11-10-2018 IPR019832 Manganese/iron superoxide dismutase, C-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_09260 89c3896b6ac5e58745e08d49b8b54aa8 258 Pfam PF00081 Iron/manganese superoxide dismutases, alpha-hairpin domain 60 140 3.3E-28 T 11-10-2018 IPR019831 Manganese/iron superoxide dismutase, N-terminal GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_09260 89c3896b6ac5e58745e08d49b8b54aa8 258 Gene3D G3DSA:1.10.287.990 77 139 4.0E-25 T 11-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_09260 89c3896b6ac5e58745e08d49b8b54aa8 258 Gene3D G3DSA:2.40.500.20 140 257 3.0E-45 T 11-10-2018 IPR036314 Manganese/iron superoxide dismutase, C-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_09260 89c3896b6ac5e58745e08d49b8b54aa8 258 PRINTS PR01703 Manganese superoxide dismutase signature 63 74 5.9E-22 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_09260 89c3896b6ac5e58745e08d49b8b54aa8 258 PRINTS PR01703 Manganese superoxide dismutase signature 84 97 5.9E-22 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_09260 89c3896b6ac5e58745e08d49b8b54aa8 258 PRINTS PR01703 Manganese superoxide dismutase signature 214 226 5.9E-22 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_09260 89c3896b6ac5e58745e08d49b8b54aa8 258 PRINTS PR01703 Manganese superoxide dismutase signature 176 184 5.9E-22 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_09260 89c3896b6ac5e58745e08d49b8b54aa8 258 PRINTS PR01703 Manganese superoxide dismutase signature 123 136 5.9E-22 T 11-10-2018 IPR001189 Manganese/iron superoxide dismutase GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_09260 89c3896b6ac5e58745e08d49b8b54aa8 258 SUPERFAMILY SSF46609 58 145 4.45E-32 T 11-10-2018 IPR036324 Manganese/iron superoxide dismutase, N-terminal domain superfamily MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_09260 89c3896b6ac5e58745e08d49b8b54aa8 258 ProSitePatterns PS00088 Manganese and iron superoxide dismutases signature. 216 223 - T 11-10-2018 IPR019833 Manganese/iron superoxide dismutase, binding site GO:0004784|GO:0006801|GO:0046872|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-8862803|Reactome: R-HSA-8950505 AFK25_13100 18f512d478d801d0a46a98d2aaeb45e5 228 SUPERFAMILY SSF52540 1 219 6.84E-73 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_13100 18f512d478d801d0a46a98d2aaeb45e5 228 Gene3D G3DSA:3.40.50.300 1 224 9.2E-68 T 11-10-2018 AFK25_13100 18f512d478d801d0a46a98d2aaeb45e5 228 Pfam PF00005 ABC transporter 18 165 1.2E-36 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_13100 18f512d478d801d0a46a98d2aaeb45e5 228 SMART SM00382 27 214 2.4E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_13100 18f512d478d801d0a46a98d2aaeb45e5 228 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_13100 18f512d478d801d0a46a98d2aaeb45e5 228 TIGRFAM TIGR02673 FtsE: cell division ATP-binding protein FtsE 1 214 1.7E-89 T 11-10-2018 IPR005286 Cell division protein FtsE, ATP-binding GO:0005524|GO:0051301 AFK25_01090 3979526559df3016c817ce484b5423f0 339 Gene3D G3DSA:2.50.20.10 23 214 4.9E-12 T 11-10-2018 AFK25_01090 3979526559df3016c817ce484b5423f0 339 SUPERFAMILY SSF89392 28 204 1.18E-17 T 11-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX AFK25_12945 4ebbde18a31ecd49c49004a993b4414a 85 ProSitePatterns PS00589 PTS HPR domain serine phosphorylation site signature. 39 54 - T 11-10-2018 IPR002114 Phosphotransferase system, HPr serine phosphorylation site AFK25_12945 4ebbde18a31ecd49c49004a993b4414a 85 Gene3D G3DSA:3.30.1340.10 1 85 3.1E-35 T 11-10-2018 IPR035895 HPr-like superfamily AFK25_12945 4ebbde18a31ecd49c49004a993b4414a 85 Pfam PF00381 PTS HPr component phosphorylation site 3 82 3.7E-30 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like AFK25_12945 4ebbde18a31ecd49c49004a993b4414a 85 SUPERFAMILY SSF55594 3 83 4.19E-28 T 11-10-2018 IPR035895 HPr-like superfamily AFK25_12945 4ebbde18a31ecd49c49004a993b4414a 85 PRINTS PR00107 Phosphocarrier protein signature 38 53 5.5E-21 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like AFK25_12945 4ebbde18a31ecd49c49004a993b4414a 85 PRINTS PR00107 Phosphocarrier protein signature 53 70 5.5E-21 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like AFK25_12945 4ebbde18a31ecd49c49004a993b4414a 85 PRINTS PR00107 Phosphocarrier protein signature 13 29 5.5E-21 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like AFK25_12945 4ebbde18a31ecd49c49004a993b4414a 85 TIGRFAM TIGR01003 PTS_HPr_family: phosphocarrier, HPr family 1 81 4.2E-30 T 11-10-2018 IPR000032 Phosphocarrier protein HPr-like AFK25_12215 21ddca08b2e8a8642257c314d70dbbdd 759 PRINTS PR01183 Ribonucleotide reductase large chain signature 536 558 5.4E-39 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_12215 21ddca08b2e8a8642257c314d70dbbdd 759 PRINTS PR01183 Ribonucleotide reductase large chain signature 445 456 5.4E-39 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_12215 21ddca08b2e8a8642257c314d70dbbdd 759 PRINTS PR01183 Ribonucleotide reductase large chain signature 628 655 5.4E-39 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_12215 21ddca08b2e8a8642257c314d70dbbdd 759 PRINTS PR01183 Ribonucleotide reductase large chain signature 296 315 5.4E-39 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_12215 21ddca08b2e8a8642257c314d70dbbdd 759 PRINTS PR01183 Ribonucleotide reductase large chain signature 564 587 5.4E-39 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_12215 21ddca08b2e8a8642257c314d70dbbdd 759 PRINTS PR01183 Ribonucleotide reductase large chain signature 496 519 5.4E-39 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_12215 21ddca08b2e8a8642257c314d70dbbdd 759 ProSitePatterns PS00089 Ribonucleotide reductase large subunit signature. 617 639 - T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_12215 21ddca08b2e8a8642257c314d70dbbdd 759 Gene3D G3DSA:3.20.70.20 71 753 1.8E-207 T 11-10-2018 AFK25_12215 21ddca08b2e8a8642257c314d70dbbdd 759 SUPERFAMILY SSF51998 220 757 2.96E-166 T 11-10-2018 AFK25_12215 21ddca08b2e8a8642257c314d70dbbdd 759 TIGRFAM TIGR02506 NrdE_NrdA: ribonucleoside-diphosphate reductase, alpha subunit 144 746 4.3E-174 T 11-10-2018 IPR013346 Ribonucleotide reductase, class I , alpha subunit GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_12215 21ddca08b2e8a8642257c314d70dbbdd 759 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 141 217 8.6E-19 T 11-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_12215 21ddca08b2e8a8642257c314d70dbbdd 759 SUPERFAMILY SSF48168 11 219 6.28E-54 T 11-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_12215 21ddca08b2e8a8642257c314d70dbbdd 759 Pfam PF02867 Ribonucleotide reductase, barrel domain 221 743 2.3E-147 T 11-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_09830 046da121bef3896063726be7392f7e4f 70 ProDom PD028235 EXONUCLEASE SMALL SUBUNIT VII EXODEOXYRIBONUCLEASE HYDROLASE NUCLEASE PROBABLE VII SIMILAR 2 39 1.0E-11 T 11-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFK25_09830 046da121bef3896063726be7392f7e4f 70 SUPERFAMILY SSF116842 1 63 4.97E-22 T 11-10-2018 AFK25_09830 046da121bef3896063726be7392f7e4f 70 TIGRFAM TIGR01280 xseB: exodeoxyribonuclease VII, small subunit 2 57 1.3E-24 T 11-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFK25_09830 046da121bef3896063726be7392f7e4f 70 Pfam PF02609 Exonuclease VII small subunit 3 53 1.9E-23 T 11-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFK25_09830 046da121bef3896063726be7392f7e4f 70 Gene3D G3DSA:1.10.287.1040 1 70 6.1E-24 T 11-10-2018 IPR037004 Exonuclease VII, small subunit superfamily GO:0006308|GO:0008855|GO:0009318 AFK25_09830 046da121bef3896063726be7392f7e4f 70 Hamap MF_00337 Exodeoxyribonuclease 7 small subunit [xseB]. 2 62 15.356 T 11-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFK25_09830 046da121bef3896063726be7392f7e4f 70 PIRSF PIRSF006488 1 70 1.0E-20 T 11-10-2018 IPR003761 Exonuclease VII, small subunit GO:0006308|GO:0008855|GO:0009318 AFK25_14560 e954fec6e6758b89a70724d12a537be5 454 Pfam PF00772 DnaB-like helicase N terminal domain 10 111 7.7E-38 T 11-10-2018 IPR007693 DNA helicase, DnaB-like, N-terminal GO:0003678|GO:0005524|GO:0006260 AFK25_14560 e954fec6e6758b89a70724d12a537be5 454 Gene3D G3DSA:3.40.50.300 167 454 3.6E-122 T 11-10-2018 AFK25_14560 e954fec6e6758b89a70724d12a537be5 454 SUPERFAMILY SSF48024 8 119 1.96E-39 T 11-10-2018 IPR036185 DNA helicase, DnaB-like, N-terminal domain superfamily GO:0003678|GO:0005524|GO:0006260 AFK25_14560 e954fec6e6758b89a70724d12a537be5 454 TIGRFAM TIGR00665 DnaB: replicative DNA helicase 9 442 4.4E-192 T 11-10-2018 IPR007692 DNA helicase, DnaB type GO:0003677|GO:0003678|GO:0005524|GO:0006260 AFK25_14560 e954fec6e6758b89a70724d12a537be5 454 SUPERFAMILY SSF52540 183 433 1.43E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_14560 e954fec6e6758b89a70724d12a537be5 454 Pfam PF03796 DnaB-like helicase C terminal domain 185 440 4.3E-120 T 11-10-2018 IPR007694 DNA helicase, DnaB-like, C-terminal GO:0003678|GO:0005524|GO:0006260 Reactome: R-HSA-2151201 AFK25_14560 e954fec6e6758b89a70724d12a537be5 454 Gene3D G3DSA:1.10.860.10 1 166 9.4E-70 T 11-10-2018 IPR016136 DNA helicase DnaB, N-terminal/DNA primase DnaG, C-terminal AFK25_05995 7cd9b5c42032aceabf4b302ebef415d1 509 Gene3D G3DSA:3.40.50.300 254 503 5.2E-43 T 11-10-2018 AFK25_05995 7cd9b5c42032aceabf4b302ebef415d1 509 Gene3D G3DSA:3.40.50.300 2 235 2.0E-56 T 11-10-2018 AFK25_05995 7cd9b5c42032aceabf4b302ebef415d1 509 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_05995 7cd9b5c42032aceabf4b302ebef415d1 509 Pfam PF00005 ABC transporter 21 169 3.3E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_05995 7cd9b5c42032aceabf4b302ebef415d1 509 Pfam PF00005 ABC transporter 274 429 9.8E-17 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_05995 7cd9b5c42032aceabf4b302ebef415d1 509 SUPERFAMILY SSF52540 238 491 5.82E-47 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_05995 7cd9b5c42032aceabf4b302ebef415d1 509 SUPERFAMILY SSF52540 3 227 1.49E-59 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_05995 7cd9b5c42032aceabf4b302ebef415d1 509 ProSitePatterns PS00211 ABC transporters family signature. 402 416 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_05995 7cd9b5c42032aceabf4b302ebef415d1 509 SMART SM00382 29 225 1.7E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_10715 aa38581564f25d824f07f93f1e457fa5 381 SUPERFAMILY SSF53383 3 377 7.53E-108 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_10715 aa38581564f25d824f07f93f1e457fa5 381 PIRSF PIRSF005572 1 381 1.9E-129 T 11-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 AFK25_10715 aa38581564f25d824f07f93f1e457fa5 381 Pfam PF00266 Aminotransferase class-V 4 366 1.7E-85 T 11-10-2018 IPR000192 Aminotransferase class V domain AFK25_10715 aa38581564f25d824f07f93f1e457fa5 381 Gene3D G3DSA:3.40.640.10 15 256 3.0E-146 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_10715 aa38581564f25d824f07f93f1e457fa5 381 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 193 212 - T 11-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site AFK25_10715 aa38581564f25d824f07f93f1e457fa5 381 Gene3D G3DSA:3.90.1150.10 4 374 3.0E-146 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_08905 2076c4b839ca3808b7a998e0113fd97b 501 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 24 487 4.1E-166 T 11-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFK25_08905 2076c4b839ca3808b7a998e0113fd97b 501 SUPERFAMILY SSF56322 14 492 1.31E-146 T 11-10-2018 IPR005801 ADC synthase GO:0009058 AFK25_08905 2076c4b839ca3808b7a998e0113fd97b 501 Gene3D G3DSA:3.60.120.10 1 497 9.8E-169 T 11-10-2018 IPR005801 ADC synthase GO:0009058 AFK25_08905 2076c4b839ca3808b7a998e0113fd97b 501 Pfam PF04715 Anthranilate synthase component I, N terminal region 25 164 4.4E-31 T 11-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFK25_08905 2076c4b839ca3808b7a998e0113fd97b 501 Pfam PF00425 chorismate binding enzyme 226 479 1.1E-94 T 11-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal AFK25_08905 2076c4b839ca3808b7a998e0113fd97b 501 PRINTS PR00095 Anthranilate synthase component I signature 341 354 4.2E-21 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFK25_08905 2076c4b839ca3808b7a998e0113fd97b 501 PRINTS PR00095 Anthranilate synthase component I signature 436 450 4.2E-21 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFK25_08905 2076c4b839ca3808b7a998e0113fd97b 501 PRINTS PR00095 Anthranilate synthase component I signature 421 435 4.2E-21 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFK25_08905 2076c4b839ca3808b7a998e0113fd97b 501 PRINTS PR00095 Anthranilate synthase component I signature 327 340 4.2E-21 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFK25_07155 492c248a895f3b6a0cbdc22d9634ed51 330 SUPERFAMILY SSF56042 157 319 7.63E-40 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFK25_07155 492c248a895f3b6a0cbdc22d9634ed51 330 Gene3D G3DSA:3.90.650.10 152 330 5.1E-51 T 11-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AFK25_07155 492c248a895f3b6a0cbdc22d9634ed51 330 Gene3D G3DSA:3.30.1330.10 5 151 1.4E-47 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFK25_07155 492c248a895f3b6a0cbdc22d9634ed51 330 Pfam PF02769 AIR synthase related protein, C-terminal domain 157 302 1.8E-24 T 11-10-2018 IPR010918 PurM-like, C-terminal domain AFK25_07155 492c248a895f3b6a0cbdc22d9634ed51 330 Pfam PF00586 AIR synthase related protein, N-terminal domain 36 147 2.0E-17 T 11-10-2018 IPR016188 PurM-like, N-terminal domain AFK25_07155 492c248a895f3b6a0cbdc22d9634ed51 330 SUPERFAMILY SSF55326 3 149 4.71E-33 T 11-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AFK25_07155 492c248a895f3b6a0cbdc22d9634ed51 330 PIRSF PIRSF005644 1 330 1.6E-118 T 11-10-2018 IPR011854 Carbamoyl dehydratase HypE AFK25_07155 492c248a895f3b6a0cbdc22d9634ed51 330 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 3 330 4.0E-130 T 11-10-2018 IPR011854 Carbamoyl dehydratase HypE AFK25_10315 1bf61615f3bdee46fe0c1afec7ff4d4a 155 Hamap MF_00009 Endoribonuclease YbeY [ybeY]. 1 155 24.879 T 11-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 AFK25_10315 1bf61615f3bdee46fe0c1afec7ff4d4a 155 Pfam PF02130 Uncharacterized protein family UPF0054 13 151 1.0E-50 T 11-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 AFK25_10315 1bf61615f3bdee46fe0c1afec7ff4d4a 155 TIGRFAM TIGR00043 TIGR00043: rRNA maturation RNase YbeY 39 151 3.3E-43 T 11-10-2018 IPR002036 Endoribonuclease YbeY GO:0004222|GO:0006364 AFK25_10315 1bf61615f3bdee46fe0c1afec7ff4d4a 155 ProSitePatterns PS01306 Uncharacterized protein family UPF0054 signature. 121 131 - T 11-10-2018 IPR020549 Endoribonuclease YbeY, conserved site AFK25_10315 1bf61615f3bdee46fe0c1afec7ff4d4a 155 SUPERFAMILY SSF55486 2 154 3.66E-47 T 11-10-2018 AFK25_10315 1bf61615f3bdee46fe0c1afec7ff4d4a 155 Gene3D G3DSA:3.40.390.30 2 155 1.8E-48 T 11-10-2018 IPR023091 Metalloprotease catalytic domain superfamily, predicted GO:0004222 AFK25_10475 470a7c55d627daf80109879b98e75fc2 188 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 67 1.5E-11 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFK25_10475 470a7c55d627daf80109879b98e75fc2 188 Gene3D G3DSA:3.40.50.620 1 187 1.5E-65 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_10475 470a7c55d627daf80109879b98e75fc2 188 Pfam PF01467 Cytidylyltransferase-like 6 161 5.1E-33 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFK25_10475 470a7c55d627daf80109879b98e75fc2 188 Hamap MF_00244 Probable nicotinate-nucleotide adenylyltransferase [nadD]. 2 187 31.721 T 11-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 AFK25_10475 470a7c55d627daf80109879b98e75fc2 188 SUPERFAMILY SSF52374 2 186 9.07E-56 T 11-10-2018 AFK25_10475 470a7c55d627daf80109879b98e75fc2 188 TIGRFAM TIGR00482 TIGR00482: nicotinate (nicotinamide) nucleotide adenylyltransferase 6 186 4.3E-59 T 11-10-2018 IPR005248 Nicotinate/nicotinamide nucleotide adenylyltransferase GO:0009435|GO:0016779 KEGG: 00760+2.7.7.18|MetaCyc: PWY-5381|MetaCyc: PWY-5653|MetaCyc: PWY-7761|Reactome: R-HSA-196807 AFK25_03770 69c89423988d0c39626d778653ecf672 178 Pfam PF01966 HD domain 25 135 3.7E-16 T 11-10-2018 IPR006674 HD domain AFK25_03770 69c89423988d0c39626d778653ecf672 178 Gene3D G3DSA:1.10.3210.10 10 172 7.3E-18 T 11-10-2018 AFK25_03770 69c89423988d0c39626d778653ecf672 178 SMART SM00471 19 148 4.3E-7 T 11-10-2018 IPR003607 HD/PDEase domain AFK25_03770 69c89423988d0c39626d778653ecf672 178 TIGRFAM TIGR00277 HDIG: HDIG domain 22 91 2.1E-10 T 11-10-2018 IPR006675 HDIG domain AFK25_03770 69c89423988d0c39626d778653ecf672 178 SUPERFAMILY SSF109604 14 137 5.89E-22 T 11-10-2018 AFK25_12905 14a696d62be109abffbec07b917719d8 251 Pfam PF00121 Triosephosphate isomerase 5 247 1.8E-95 T 11-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12905 14a696d62be109abffbec07b917719d8 251 SUPERFAMILY SSF51351 1 248 7.98E-95 T 11-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12905 14a696d62be109abffbec07b917719d8 251 Gene3D G3DSA:3.20.20.70 2 251 7.3E-107 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_12905 14a696d62be109abffbec07b917719d8 251 Hamap MF_00147_B Triosephosphate isomerase [tpiA]. 2 249 60.728 T 11-10-2018 IPR022896 Triosephosphate isomerase, bacterial/eukaryotic GO:0004807|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12905 14a696d62be109abffbec07b917719d8 251 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 5 240 3.3E-56 T 11-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12905 14a696d62be109abffbec07b917719d8 251 ProSitePatterns PS00171 Triosephosphate isomerase active site. 165 175 - T 11-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_06505 47794e3d6beb0118aa10a757f196ae48 295 Gene3D G3DSA:3.40.50.12740 3 175 1.1E-23 T 11-10-2018 AFK25_06505 47794e3d6beb0118aa10a757f196ae48 295 Pfam PF08664 YcbB domain 154 287 1.3E-48 T 11-10-2018 IPR013972 YcbB domain AFK25_06505 47794e3d6beb0118aa10a757f196ae48 295 Pfam PF00072 Response regulator receiver domain 4 112 1.4E-19 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_06505 47794e3d6beb0118aa10a757f196ae48 295 SUPERFAMILY SSF52172 3 133 1.57E-23 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_06505 47794e3d6beb0118aa10a757f196ae48 295 SMART SM00448 1 113 2.8E-18 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_10900 3459e219b591d20be297c50d07675cc9 287 ProSitePatterns PS00858 Prephenate dehydratase signature 2. 226 233 - T 11-10-2018 IPR018528 Prephenate dehydratase, conserved site GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 AFK25_10900 3459e219b591d20be297c50d07675cc9 287 Gene3D G3DSA:3.40.190.10 5 180 3.6E-56 T 11-10-2018 AFK25_10900 3459e219b591d20be297c50d07675cc9 287 SUPERFAMILY SSF53850 2 187 1.81E-55 T 11-10-2018 AFK25_10900 3459e219b591d20be297c50d07675cc9 287 Pfam PF00800 Prephenate dehydratase 3 183 4.5E-59 T 11-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 AFK25_10900 3459e219b591d20be297c50d07675cc9 287 Gene3D G3DSA:3.40.190.10 83 172 3.6E-56 T 11-10-2018 AFK25_10900 3459e219b591d20be297c50d07675cc9 287 SUPERFAMILY SSF55021 177 278 3.38E-25 T 11-10-2018 AFK25_10900 3459e219b591d20be297c50d07675cc9 287 Gene3D G3DSA:3.30.70.260 189 284 3.4E-26 T 11-10-2018 AFK25_10900 3459e219b591d20be297c50d07675cc9 287 PIRSF PIRSF001500 1 281 1.2E-72 T 11-10-2018 IPR008242 Bifunctional P-protein, chorismate mutase/prephenate dehydratase GO:0004106|GO:0004664|GO:0005737|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 AFK25_04345 4c67275c7255c7e75fef0970606a9084 472 Hamap MF_02103 Lactate utilization protein B [lutB]. 1 472 66.817 T 11-10-2018 IPR022825 Lactate utilization protein B AFK25_04345 4c67275c7255c7e75fef0970606a9084 472 SUPERFAMILY SSF46548 272 393 5.76E-17 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFK25_04345 4c67275c7255c7e75fef0970606a9084 472 Pfam PF13183 4Fe-4S dicluster domain 311 377 4.5E-10 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFK25_04345 4c67275c7255c7e75fef0970606a9084 472 SUPERFAMILY SSF100950 64 296 2.22E-39 T 11-10-2018 IPR037171 NagB/RpiA transferase-like AFK25_04345 4c67275c7255c7e75fef0970606a9084 472 Pfam PF02589 LUD domain 71 295 7.2E-56 T 11-10-2018 IPR003741 LUD domain AFK25_04345 4c67275c7255c7e75fef0970606a9084 472 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 18 455 4.9E-208 T 11-10-2018 IPR004452 4Fe-4S binding protein GO:0019516 AFK25_04345 4c67275c7255c7e75fef0970606a9084 472 Pfam PF11870 Domain of unknown function (DUF3390) 385 470 8.2E-21 T 11-10-2018 IPR024569 4Fe-4S binding protein, C-terminal AFK25_04345 4c67275c7255c7e75fef0970606a9084 472 Gene3D G3DSA:3.40.50.10420 122 295 2.9E-15 T 11-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily AFK25_04345 4c67275c7255c7e75fef0970606a9084 472 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 313 324 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFK25_04665 6e2a89cb8157222fa8994faf5e1c7ea6 659 Gene3D G3DSA:1.10.287.950 356 658 4.3E-66 T 11-10-2018 AFK25_04665 6e2a89cb8157222fa8994faf5e1c7ea6 659 Gene3D G3DSA:3.30.450.20 94 182 3.6E-43 T 11-10-2018 AFK25_04665 6e2a89cb8157222fa8994faf5e1c7ea6 659 Pfam PF00672 HAMP domain 302 349 4.1E-12 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_04665 6e2a89cb8157222fa8994faf5e1c7ea6 659 Gene3D G3DSA:1.10.8.500 300 353 1.3E-8 T 11-10-2018 AFK25_04665 6e2a89cb8157222fa8994faf5e1c7ea6 659 SUPERFAMILY SSF58104 322 657 3.01E-69 T 11-10-2018 AFK25_04665 6e2a89cb8157222fa8994faf5e1c7ea6 659 Gene3D G3DSA:3.30.450.20 183 275 3.6E-43 T 11-10-2018 AFK25_04665 6e2a89cb8157222fa8994faf5e1c7ea6 659 SMART SM00304 302 354 4.6E-15 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_04665 6e2a89cb8157222fa8994faf5e1c7ea6 659 Pfam PF02743 Cache domain 36 264 1.3E-38 T 11-10-2018 IPR033479 Double Cache domain 1 AFK25_04665 6e2a89cb8157222fa8994faf5e1c7ea6 659 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 510 539 3.3E-22 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_04665 6e2a89cb8157222fa8994faf5e1c7ea6 659 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 558 587 3.3E-22 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_04665 6e2a89cb8157222fa8994faf5e1c7ea6 659 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 407 436 3.3E-22 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_04665 6e2a89cb8157222fa8994faf5e1c7ea6 659 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 481 508 3.3E-22 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_04665 6e2a89cb8157222fa8994faf5e1c7ea6 659 SMART SM00283 383 658 1.3E-67 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_04665 6e2a89cb8157222fa8994faf5e1c7ea6 659 SUPERFAMILY SSF103190 78 193 3.34E-15 T 11-10-2018 IPR029151 Periplasmic sensor-like domain superfamily AFK25_04665 6e2a89cb8157222fa8994faf5e1c7ea6 659 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 449 611 7.4E-38 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_14650 a7aad49d77726511a24c5bc3efaa3ee5 205 Gene3D G3DSA:3.30.1370.50 140 205 1.4E-27 T 11-10-2018 IPR036867 R3H domain superfamily GO:0003676 AFK25_14650 a7aad49d77726511a24c5bc3efaa3ee5 205 Pfam PF13083 KH domain 63 126 1.3E-16 T 11-10-2018 AFK25_14650 a7aad49d77726511a24c5bc3efaa3ee5 205 SUPERFAMILY SSF82708 147 202 2.16E-8 T 11-10-2018 IPR036867 R3H domain superfamily GO:0003676 AFK25_14650 a7aad49d77726511a24c5bc3efaa3ee5 205 SMART SM00393 125 204 2.1E-14 T 11-10-2018 IPR001374 R3H domain GO:0003676 AFK25_14650 a7aad49d77726511a24c5bc3efaa3ee5 205 Pfam PF01424 R3H domain 143 202 1.2E-15 T 11-10-2018 IPR001374 R3H domain GO:0003676 AFK25_14650 a7aad49d77726511a24c5bc3efaa3ee5 205 Gene3D G3DSA:3.30.30.80 1 56 8.9E-16 T 11-10-2018 IPR038247 Jag, N-terminal domain superfamily AFK25_14650 a7aad49d77726511a24c5bc3efaa3ee5 205 SMART SM01245 5 57 6.4E-21 T 11-10-2018 IPR032782 Jag, N-terminal AFK25_14650 a7aad49d77726511a24c5bc3efaa3ee5 205 Gene3D G3DSA:3.30.300.20 60 139 2.3E-23 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta AFK25_14650 a7aad49d77726511a24c5bc3efaa3ee5 205 Pfam PF14804 Jag N-terminus 6 56 1.6E-18 T 11-10-2018 IPR032782 Jag, N-terminal AFK25_11650 99c27021d54271530a82a27352a128ae 290 Pfam PF01039 Carboxyl transferase domain 63 242 6.4E-21 T 11-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 AFK25_11650 99c27021d54271530a82a27352a128ae 290 TIGRFAM TIGR00515 accD: acetyl-CoA carboxylase, carboxyl transferase, beta subunit 16 281 3.1E-132 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFK25_11650 99c27021d54271530a82a27352a128ae 290 Hamap MF_01395 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta, chloroplastic [accD]. 3 281 39.329 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFK25_11650 99c27021d54271530a82a27352a128ae 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 200 217 3.1E-38 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFK25_11650 99c27021d54271530a82a27352a128ae 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 163 181 3.1E-38 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFK25_11650 99c27021d54271530a82a27352a128ae 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 229 240 3.1E-38 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFK25_11650 99c27021d54271530a82a27352a128ae 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 251 260 3.1E-38 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFK25_11650 99c27021d54271530a82a27352a128ae 290 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 129 143 3.1E-38 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFK25_11650 99c27021d54271530a82a27352a128ae 290 SUPERFAMILY SSF52096 28 280 1.06E-84 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFK25_11650 99c27021d54271530a82a27352a128ae 290 Gene3D G3DSA:3.90.226.10 28 282 4.3E-91 T 11-10-2018 AFK25_03265 69913f46b582af0ea224b075bd27d39a 403 PIRSF PIRSF036428 1 399 1.5E-116 T 11-10-2018 IPR006365 Cobalamin (vitamin B12) biosynthesis CobL/Precorrin-6Y C(5,15)-methyltransferase GO:0008276|GO:0009236 KEGG: 00860+2.1.1.132 AFK25_03265 69913f46b582af0ea224b075bd27d39a 403 Gene3D G3DSA:3.40.1010.10 2 99 4.8E-14 T 11-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFK25_03265 69913f46b582af0ea224b075bd27d39a 403 Gene3D G3DSA:3.40.50.150 205 403 5.8E-70 T 11-10-2018 AFK25_03265 69913f46b582af0ea224b075bd27d39a 403 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 235 344 2.1E-4 T 11-10-2018 AFK25_03265 69913f46b582af0ea224b075bd27d39a 403 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 6 198 1.3E-55 T 11-10-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 AFK25_03265 69913f46b582af0ea224b075bd27d39a 403 TIGRFAM TIGR02469 CbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit 227 347 1.6E-34 T 11-10-2018 IPR014008 Cobalamin biosynthesis, precorrin-6Y methyltransferase, CbiT subunit GO:0008276|GO:0009236 KEGG: 00860+2.1.1.196|MetaCyc: PWY-7377 AFK25_03265 69913f46b582af0ea224b075bd27d39a 403 SUPERFAMILY SSF53335 215 388 1.12E-25 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_03265 69913f46b582af0ea224b075bd27d39a 403 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 6 186 6.9E-17 T 11-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFK25_03265 69913f46b582af0ea224b075bd27d39a 403 SUPERFAMILY SSF53790 5 200 2.22E-35 T 11-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFK25_01540 f81d5b1b2ebd9174d5c55a0b0b72986d 251 Pfam PF01695 IstB-like ATP binding protein 53 228 2.4E-73 T 11-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 AFK25_01540 f81d5b1b2ebd9174d5c55a0b0b72986d 251 SUPERFAMILY SSF52540 64 225 6.86E-29 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_01540 f81d5b1b2ebd9174d5c55a0b0b72986d 251 PIRSF PIRSF003073 1 251 1.2E-87 T 11-10-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein AFK25_01540 f81d5b1b2ebd9174d5c55a0b0b72986d 251 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 188 202 3.9E-5 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_01540 f81d5b1b2ebd9174d5c55a0b0b72986d 251 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 101 119 3.9E-5 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_01540 f81d5b1b2ebd9174d5c55a0b0b72986d 251 SMART SM00382 97 229 7.9E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_01540 f81d5b1b2ebd9174d5c55a0b0b72986d 251 Gene3D G3DSA:3.40.50.300 60 248 3.4E-59 T 11-10-2018 AFK25_07790 f81d5b1b2ebd9174d5c55a0b0b72986d 251 Pfam PF01695 IstB-like ATP binding protein 53 228 2.4E-73 T 11-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 AFK25_07790 f81d5b1b2ebd9174d5c55a0b0b72986d 251 SUPERFAMILY SSF52540 64 225 6.86E-29 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_07790 f81d5b1b2ebd9174d5c55a0b0b72986d 251 PIRSF PIRSF003073 1 251 1.2E-87 T 11-10-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein AFK25_07790 f81d5b1b2ebd9174d5c55a0b0b72986d 251 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 188 202 3.9E-5 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_07790 f81d5b1b2ebd9174d5c55a0b0b72986d 251 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 101 119 3.9E-5 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_07790 f81d5b1b2ebd9174d5c55a0b0b72986d 251 SMART SM00382 97 229 7.9E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_07790 f81d5b1b2ebd9174d5c55a0b0b72986d 251 Gene3D G3DSA:3.40.50.300 60 248 3.4E-59 T 11-10-2018 AFK25_13680 f81d5b1b2ebd9174d5c55a0b0b72986d 251 Pfam PF01695 IstB-like ATP binding protein 53 228 2.4E-73 T 11-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 AFK25_13680 f81d5b1b2ebd9174d5c55a0b0b72986d 251 SUPERFAMILY SSF52540 64 225 6.86E-29 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_13680 f81d5b1b2ebd9174d5c55a0b0b72986d 251 PIRSF PIRSF003073 1 251 1.2E-87 T 11-10-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein AFK25_13680 f81d5b1b2ebd9174d5c55a0b0b72986d 251 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 188 202 3.9E-5 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_13680 f81d5b1b2ebd9174d5c55a0b0b72986d 251 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 101 119 3.9E-5 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_13680 f81d5b1b2ebd9174d5c55a0b0b72986d 251 SMART SM00382 97 229 7.9E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_13680 f81d5b1b2ebd9174d5c55a0b0b72986d 251 Gene3D G3DSA:3.40.50.300 60 248 3.4E-59 T 11-10-2018 AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 171 189 1.1E-32 T 11-10-2018 AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 274 1.1E-32 T 11-10-2018 AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 150 1.1E-32 T 11-10-2018 AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 287 309 1.1E-32 T 11-10-2018 AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 1.1E-32 T 11-10-2018 AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 4 322 1.2E-59 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 Gene3D G3DSA:3.30.390.30 341 458 6.2E-31 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 SUPERFAMILY SSF51905 2 368 4.58E-56 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 Gene3D G3DSA:3.50.50.60 144 265 1.1E-101 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 342 448 1.4E-24 T 11-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 SUPERFAMILY SSF55424 338 453 1.89E-29 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 Gene3D G3DSA:3.50.50.60 4 324 1.1E-101 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 1.0E-59 T 11-10-2018 AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 171 196 1.0E-59 T 11-10-2018 AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 402 417 1.0E-59 T 11-10-2018 AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 135 144 1.0E-59 T 11-10-2018 AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 302 309 1.0E-59 T 11-10-2018 AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 259 273 1.0E-59 T 11-10-2018 AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 5 27 1.0E-59 T 11-10-2018 AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 338 359 1.0E-59 T 11-10-2018 AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 424 444 1.0E-59 T 11-10-2018 AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 11-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 AFK25_07340 4dd6ad50432a1c7b9c666fc058dd4b0e 475 PIRSF PIRSF000350 1 456 1.1E-96 T 11-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 AFK25_13065 71b8bd0998e239bcaee8f832ec57baf6 657 SMART SM00490 458 544 1.2E-21 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_13065 71b8bd0998e239bcaee8f832ec57baf6 657 Gene3D G3DSA:3.40.50.300 272 412 5.2E-56 T 11-10-2018 AFK25_13065 71b8bd0998e239bcaee8f832ec57baf6 657 SUPERFAMILY SSF52540 3 413 9.27E-149 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_13065 71b8bd0998e239bcaee8f832ec57baf6 657 Pfam PF02151 UvrB/uvrC motif 623 655 1.4E-9 T 11-10-2018 IPR001943 UVR domain GO:0005515 AFK25_13065 71b8bd0998e239bcaee8f832ec57baf6 657 Pfam PF12344 Ultra-violet resistance protein B 550 591 8.0E-22 T 11-10-2018 IPR024759 UvrB, YAD/RRR-motif-containing domain AFK25_13065 71b8bd0998e239bcaee8f832ec57baf6 657 Pfam PF04851 Type III restriction enzyme, res subunit 10 137 5.1E-13 T 11-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFK25_13065 71b8bd0998e239bcaee8f832ec57baf6 657 SUPERFAMILY SSF52540 31 591 5.44E-39 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_13065 71b8bd0998e239bcaee8f832ec57baf6 657 TIGRFAM TIGR00631 uvrb: excinuclease ABC subunit B 4 654 0.0 T 11-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 AFK25_13065 71b8bd0998e239bcaee8f832ec57baf6 657 Pfam PF00271 Helicase conserved C-terminal domain 433 543 2.4E-19 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_13065 71b8bd0998e239bcaee8f832ec57baf6 657 SUPERFAMILY SSF46600 610 655 1.44E-10 T 11-10-2018 IPR036876 UVR domain superfamily AFK25_13065 71b8bd0998e239bcaee8f832ec57baf6 657 SMART SM00487 8 424 6.3E-28 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFK25_13065 71b8bd0998e239bcaee8f832ec57baf6 657 Hamap MF_00204 UvrABC system protein B [uvrB]. 2 656 45.411 T 11-10-2018 IPR004807 UvrABC system, subunit B GO:0003677|GO:0005524|GO:0006289|GO:0009380|GO:0016887 AFK25_13065 71b8bd0998e239bcaee8f832ec57baf6 657 Gene3D G3DSA:3.40.50.300 1 242 2.8E-83 T 11-10-2018 AFK25_13065 71b8bd0998e239bcaee8f832ec57baf6 657 Gene3D G3DSA:3.40.50.300 413 594 2.2E-54 T 11-10-2018 AFK25_13065 71b8bd0998e239bcaee8f832ec57baf6 657 Gene3D G3DSA:4.10.860.10 605 657 3.2E-5 T 11-10-2018 AFK25_05445 a9a88d5f7984591117a11f0adbc97d7e 642 Pfam PF03793 PASTA domain 491 551 2.5E-12 T 11-10-2018 IPR005543 PASTA domain AFK25_05445 a9a88d5f7984591117a11f0adbc97d7e 642 Pfam PF03793 PASTA domain 426 484 7.9E-10 T 11-10-2018 IPR005543 PASTA domain AFK25_05445 a9a88d5f7984591117a11f0adbc97d7e 642 Pfam PF03793 PASTA domain 354 414 4.5E-16 T 11-10-2018 IPR005543 PASTA domain AFK25_05445 a9a88d5f7984591117a11f0adbc97d7e 642 ProSitePatterns PS00108 Serine/Threonine protein kinases active-site signature. 130 142 - T 11-10-2018 IPR008271 Serine/threonine-protein kinase, active site GO:0004672|GO:0006468 AFK25_05445 a9a88d5f7984591117a11f0adbc97d7e 642 Gene3D G3DSA:2.60.40.2560 559 638 5.1E-11 T 11-10-2018 AFK25_05445 a9a88d5f7984591117a11f0adbc97d7e 642 SMART SM00220 11 269 5.2E-69 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFK25_05445 a9a88d5f7984591117a11f0adbc97d7e 642 SMART SM00740 350 417 7.1E-16 T 11-10-2018 IPR005543 PASTA domain AFK25_05445 a9a88d5f7984591117a11f0adbc97d7e 642 SMART SM00740 486 552 4.4E-13 T 11-10-2018 IPR005543 PASTA domain AFK25_05445 a9a88d5f7984591117a11f0adbc97d7e 642 SMART SM00740 418 485 5.0E-5 T 11-10-2018 IPR005543 PASTA domain AFK25_05445 a9a88d5f7984591117a11f0adbc97d7e 642 Gene3D G3DSA:3.30.10.20 419 488 2.7E-12 T 11-10-2018 AFK25_05445 a9a88d5f7984591117a11f0adbc97d7e 642 Gene3D G3DSA:3.30.200.20 1 90 3.3E-33 T 11-10-2018 AFK25_05445 a9a88d5f7984591117a11f0adbc97d7e 642 Gene3D G3DSA:1.10.510.10 92 278 7.6E-54 T 11-10-2018 AFK25_05445 a9a88d5f7984591117a11f0adbc97d7e 642 SUPERFAMILY SSF54184 353 414 3.79E-5 T 11-10-2018 AFK25_05445 a9a88d5f7984591117a11f0adbc97d7e 642 Gene3D G3DSA:3.30.10.20 490 554 2.8E-14 T 11-10-2018 AFK25_05445 a9a88d5f7984591117a11f0adbc97d7e 642 Gene3D G3DSA:3.30.10.20 353 418 6.9E-17 T 11-10-2018 AFK25_05445 a9a88d5f7984591117a11f0adbc97d7e 642 SUPERFAMILY SSF56112 7 270 5.93E-84 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily AFK25_05445 a9a88d5f7984591117a11f0adbc97d7e 642 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 17 40 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFK25_05445 a9a88d5f7984591117a11f0adbc97d7e 642 Pfam PF00069 Protein kinase domain 11 258 1.1E-55 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFK25_04770 70812cb49db152683aefb8fda514d163 503 SUPERFAMILY SSF109604 309 499 1.48E-26 T 11-10-2018 AFK25_04770 70812cb49db152683aefb8fda514d163 503 SUPERFAMILY SSF53067 3 124 9.06E-28 T 11-10-2018 AFK25_04770 70812cb49db152683aefb8fda514d163 503 Gene3D G3DSA:1.10.3210.10 308 500 4.8E-33 T 11-10-2018 AFK25_04770 70812cb49db152683aefb8fda514d163 503 Gene3D G3DSA:3.30.420.40 1 107 1.9E-23 T 11-10-2018 AFK25_04770 70812cb49db152683aefb8fda514d163 503 Pfam PF02541 Ppx/GppA phosphatase family 34 299 2.9E-48 T 11-10-2018 IPR003695 Ppx/GppA phosphatase KEGG: 00230+3.6.1.40 AFK25_04770 70812cb49db152683aefb8fda514d163 503 Gene3D G3DSA:3.30.420.150 108 298 3.2E-54 T 11-10-2018 AFK25_04770 70812cb49db152683aefb8fda514d163 503 SUPERFAMILY SSF53067 127 302 2.71E-42 T 11-10-2018 AFK25_04105 3491b8847aeed71e77f616f01e0ea589 516 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 227 507 22.848 T 11-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AFK25_04105 3491b8847aeed71e77f616f01e0ea589 516 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 3 213 2.1E-51 T 11-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AFK25_04105 3491b8847aeed71e77f616f01e0ea589 516 PIRSF PIRSF017184 1 509 2.1E-152 T 11-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 AFK25_04105 3491b8847aeed71e77f616f01e0ea589 516 ProSitePatterns PS01050 YjeF C-terminal domain signature 2. 441 451 - T 11-10-2018 IPR017953 Carbohydrate kinase, predicted, conserved site AFK25_04105 3491b8847aeed71e77f616f01e0ea589 516 Gene3D G3DSA:3.40.50.10260 1 218 1.9E-64 T 11-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 AFK25_04105 3491b8847aeed71e77f616f01e0ea589 516 SUPERFAMILY SSF64153 1 248 1.96E-63 T 11-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 AFK25_04105 3491b8847aeed71e77f616f01e0ea589 516 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 5 212 25.004 T 11-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AFK25_04105 3491b8847aeed71e77f616f01e0ea589 516 Gene3D G3DSA:3.40.1190.20 219 504 1.0E-86 T 11-10-2018 IPR029056 Ribokinase-like AFK25_04105 3491b8847aeed71e77f616f01e0ea589 516 Pfam PF01256 Carbohydrate kinase 251 499 1.9E-59 T 11-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AFK25_04105 3491b8847aeed71e77f616f01e0ea589 516 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 226 501 6.5E-69 T 11-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AFK25_04105 3491b8847aeed71e77f616f01e0ea589 516 Pfam PF03853 YjeF-related protein N-terminus 25 190 1.5E-46 T 11-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AFK25_04105 3491b8847aeed71e77f616f01e0ea589 516 SUPERFAMILY SSF53613 225 503 1.96E-73 T 11-10-2018 IPR029056 Ribokinase-like AFK25_01850 f24f3fbd6e04836034bf721d4e9c8d92 337 Gene3D G3DSA:3.90.180.10 13 327 5.9E-145 T 11-10-2018 AFK25_01850 f24f3fbd6e04836034bf721d4e9c8d92 337 Gene3D G3DSA:3.40.50.720 149 285 5.9E-145 T 11-10-2018 AFK25_01850 f24f3fbd6e04836034bf721d4e9c8d92 337 Pfam PF00107 Zinc-binding dehydrogenase 175 300 4.3E-34 T 11-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AFK25_01850 f24f3fbd6e04836034bf721d4e9c8d92 337 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 26 134 3.8E-38 T 11-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AFK25_01850 f24f3fbd6e04836034bf721d4e9c8d92 337 SUPERFAMILY SSF51735 138 305 9.08E-50 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_01850 f24f3fbd6e04836034bf721d4e9c8d92 337 SMART SM00829 8 334 2.4E-8 T 11-10-2018 IPR020843 Polyketide synthase, enoylreductase domain GO:0016491 AFK25_01850 f24f3fbd6e04836034bf721d4e9c8d92 337 SUPERFAMILY SSF50129 1 161 7.61E-62 T 11-10-2018 IPR011032 GroES-like superfamily AFK25_01850 f24f3fbd6e04836034bf721d4e9c8d92 337 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 60 74 - T 11-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AFK25_06475 472d338027316ebcf98da8cf1c71d54e 466 SUPERFAMILY SSF52794 374 463 7.59E-28 T 11-10-2018 IPR036095 PTS system IIB component-like superfamily GO:0008982|GO:0009401 AFK25_06475 472d338027316ebcf98da8cf1c71d54e 466 Gene3D G3DSA:3.40.50.2300 365 465 4.9E-40 T 11-10-2018 AFK25_06475 472d338027316ebcf98da8cf1c71d54e 466 Pfam PF02378 Phosphotransferase system, EIIC 20 278 2.4E-20 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 AFK25_06475 472d338027316ebcf98da8cf1c71d54e 466 Pfam PF02302 PTS system, Lactose/Cellobiose specific IIB subunit 377 460 7.3E-14 T 11-10-2018 IPR003501 Phosphotransferase system, EIIB component, type 2/3 GO:0008982|GO:0009401 AFK25_06475 472d338027316ebcf98da8cf1c71d54e 466 TIGRFAM TIGR00851 mtlA: PTS system, mannitol-specific IIC component 10 346 1.2E-187 T 11-10-2018 IPR004718 Phosphotransferase system, mannitol-specific enzyme IIC GO:0008982|GO:0009401|GO:0016021 KEGG: 00051+2.7.1.197 AFK25_10570 b52f1a3204835584e8da35cf4b12591c 592 TIGRFAM TIGR01908 cas_CXXC_CXXC: CRISPR-associated protein Cas8b1/Cst1, subtype I-B/TNEAP 477 544 5.1E-7 T 11-10-2018 IPR010180 CRISPR-associated protein, CXXC-CXXC AFK25_02940 4d27a66148d317d20f33c6086806dacc 549 ProSitePatterns PS00457 Sodium:solute symporter family signature 2. 456 476 - T 11-10-2018 IPR018212 Sodium/solute symporter, conserved site AFK25_02940 4d27a66148d317d20f33c6086806dacc 549 Gene3D G3DSA:1.20.1730.10 21 546 3.1E-70 T 11-10-2018 IPR038377 Sodium/glucose symporter superfamily AFK25_02940 4d27a66148d317d20f33c6086806dacc 549 Pfam PF00474 Sodium:solute symporter family 354 474 6.4E-21 T 11-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AFK25_02940 4d27a66148d317d20f33c6086806dacc 549 Pfam PF00474 Sodium:solute symporter family 34 290 2.8E-41 T 11-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AFK25_02940 4d27a66148d317d20f33c6086806dacc 549 TIGRFAM TIGR03648 Na_symport_lg: probable sodium:solute symporter, VC_2705 subfamily 10 536 3.1E-225 T 11-10-2018 IPR019899 Sodium/solute symporter, VC2705 subfamily AFK25_02940 4d27a66148d317d20f33c6086806dacc 549 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 34 474 6.6E-59 T 11-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AFK25_07260 c7e1f4832d3a8964c88957826d0c2b7f 300 Gene3D G3DSA:3.40.50.170 104 300 2.7E-73 T 11-10-2018 AFK25_07260 c7e1f4832d3a8964c88957826d0c2b7f 300 PIRSF PIRSF036480 17 300 6.7E-117 T 11-10-2018 AFK25_07260 c7e1f4832d3a8964c88957826d0c2b7f 300 Pfam PF01842 ACT domain 21 73 3.9E-10 T 11-10-2018 IPR002912 ACT domain AFK25_07260 c7e1f4832d3a8964c88957826d0c2b7f 300 Gene3D G3DSA:3.30.70.260 13 102 3.0E-27 T 11-10-2018 AFK25_07260 c7e1f4832d3a8964c88957826d0c2b7f 300 SUPERFAMILY SSF53328 104 300 1.31E-61 T 11-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFK25_07260 c7e1f4832d3a8964c88957826d0c2b7f 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 22 48 1.8E-64 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 AFK25_07260 c7e1f4832d3a8964c88957826d0c2b7f 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 273 298 1.8E-64 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 AFK25_07260 c7e1f4832d3a8964c88957826d0c2b7f 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 127 154 1.8E-64 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 AFK25_07260 c7e1f4832d3a8964c88957826d0c2b7f 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 105 127 1.8E-64 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 AFK25_07260 c7e1f4832d3a8964c88957826d0c2b7f 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 55 67 1.8E-64 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 AFK25_07260 c7e1f4832d3a8964c88957826d0c2b7f 300 PRINTS PR01575 Formyltetrahydrofolate deformylase signature 251 273 1.8E-64 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 AFK25_07260 c7e1f4832d3a8964c88957826d0c2b7f 300 Hamap MF_01927 Formyltetrahydrofolate deformylase [purU]. 17 299 47.621 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 AFK25_07260 c7e1f4832d3a8964c88957826d0c2b7f 300 TIGRFAM TIGR00655 PurU: formyltetrahydrofolate deformylase 21 299 5.6E-129 T 11-10-2018 IPR004810 Formyltetrahydrofolate deformylase GO:0006189|GO:0008864 KEGG: 00630+3.5.1.10|KEGG: 00670+3.5.1.10|MetaCyc: PWY-2201|MetaCyc: PWY-5497|MetaCyc: PWY-7909 AFK25_07260 c7e1f4832d3a8964c88957826d0c2b7f 300 Pfam PF00551 Formyl transferase 104 281 2.0E-41 T 11-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFK25_07260 c7e1f4832d3a8964c88957826d0c2b7f 300 SUPERFAMILY SSF55021 19 100 4.23E-17 T 11-10-2018 AFK25_13295 0ffddd0bd3c65679eb2d7c56b2e58f77 226 Pfam PF00196 Bacterial regulatory proteins, luxR family 162 217 1.7E-25 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_13295 0ffddd0bd3c65679eb2d7c56b2e58f77 226 Gene3D G3DSA:3.40.50.12740 4 223 4.2E-74 T 11-10-2018 AFK25_13295 0ffddd0bd3c65679eb2d7c56b2e58f77 226 SUPERFAMILY SSF52172 3 134 3.27E-36 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_13295 0ffddd0bd3c65679eb2d7c56b2e58f77 226 SUPERFAMILY SSF46894 154 224 2.69E-25 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFK25_13295 0ffddd0bd3c65679eb2d7c56b2e58f77 226 SMART SM00421 160 217 2.2E-29 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_13295 0ffddd0bd3c65679eb2d7c56b2e58f77 226 Pfam PF00072 Response regulator receiver domain 5 117 8.0E-33 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_13295 0ffddd0bd3c65679eb2d7c56b2e58f77 226 SMART SM00448 3 116 1.2E-30 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_13295 0ffddd0bd3c65679eb2d7c56b2e58f77 226 ProSitePatterns PS00622 LuxR-type HTH domain signature. 177 204 - T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_13295 0ffddd0bd3c65679eb2d7c56b2e58f77 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 193 205 2.5E-15 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_13295 0ffddd0bd3c65679eb2d7c56b2e58f77 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 163 177 2.5E-15 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_13295 0ffddd0bd3c65679eb2d7c56b2e58f77 226 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 177 193 2.5E-15 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_04715 753a12e7cd309ef16d904ff320afb047 536 Pfam PF00072 Response regulator receiver domain 409 528 1.0E-21 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_04715 753a12e7cd309ef16d904ff320afb047 536 Pfam PF00072 Response regulator receiver domain 110 221 1.0E-21 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_04715 753a12e7cd309ef16d904ff320afb047 536 SUPERFAMILY SSF52172 107 246 3.13E-33 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_04715 753a12e7cd309ef16d904ff320afb047 536 SUPERFAMILY SSF55073 240 396 4.32E-48 T 11-10-2018 IPR029787 Nucleotide cyclase AFK25_04715 753a12e7cd309ef16d904ff320afb047 536 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 236 396 9.2E-49 T 11-10-2018 IPR000160 GGDEF domain AFK25_04715 753a12e7cd309ef16d904ff320afb047 536 SUPERFAMILY SSF47226 2 71 1.57E-6 T 11-10-2018 IPR036641 HPT domain superfamily GO:0000160 AFK25_04715 753a12e7cd309ef16d904ff320afb047 536 Gene3D G3DSA:3.40.50.2300 94 232 2.6E-29 T 11-10-2018 AFK25_04715 753a12e7cd309ef16d904ff320afb047 536 Gene3D G3DSA:1.20.120.160 2 91 1.5E-5 T 11-10-2018 IPR036641 HPT domain superfamily GO:0000160 AFK25_04715 753a12e7cd309ef16d904ff320afb047 536 Gene3D G3DSA:3.30.70.270 233 402 2.3E-52 T 11-10-2018 AFK25_04715 753a12e7cd309ef16d904ff320afb047 536 SUPERFAMILY SSF52172 404 535 1.85E-29 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_04715 753a12e7cd309ef16d904ff320afb047 536 Gene3D G3DSA:3.40.50.2300 403 536 1.3E-30 T 11-10-2018 AFK25_04715 753a12e7cd309ef16d904ff320afb047 536 SMART SM00448 407 528 3.4E-32 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_04715 753a12e7cd309ef16d904ff320afb047 536 SMART SM00448 108 221 5.3E-26 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_04715 753a12e7cd309ef16d904ff320afb047 536 Pfam PF00990 Diguanylate cyclase, GGDEF domain 237 391 1.2E-41 T 11-10-2018 IPR000160 GGDEF domain AFK25_04715 753a12e7cd309ef16d904ff320afb047 536 SMART SM00267 223 396 1.0E-50 T 11-10-2018 IPR000160 GGDEF domain AFK25_04715 753a12e7cd309ef16d904ff320afb047 536 Pfam PF01627 Hpt domain 7 64 3.4E-5 T 11-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 AFK25_10890 10f49c6bc414c49d0cb08342aae50475 378 Gene3D G3DSA:1.10.260.50 13 277 1.3E-123 T 11-10-2018 AFK25_10890 10f49c6bc414c49d0cb08342aae50475 378 PIRSF PIRSF005572 1 377 5.4E-119 T 11-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 AFK25_10890 10f49c6bc414c49d0cb08342aae50475 378 SUPERFAMILY SSF53383 1 372 9.71E-98 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_10890 10f49c6bc414c49d0cb08342aae50475 378 Gene3D G3DSA:3.90.1150.10 2 368 1.3E-123 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_10890 10f49c6bc414c49d0cb08342aae50475 378 Pfam PF00266 Aminotransferase class-V 2 363 2.6E-77 T 11-10-2018 IPR000192 Aminotransferase class V domain AFK25_10890 10f49c6bc414c49d0cb08342aae50475 378 Gene3D G3DSA:3.40.640.10 59 233 1.3E-123 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_03605 e345517fbbca0ecdd2ac3a9ed74f353a 424 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 404 1.8E-141 T 11-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFK25_03605 e345517fbbca0ecdd2ac3a9ed74f353a 424 SUPERFAMILY SSF51735 1 190 1.22E-49 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_03605 e345517fbbca0ecdd2ac3a9ed74f353a 424 Gene3D G3DSA:3.40.50.720 226 424 8.2E-69 T 11-10-2018 AFK25_03605 e345517fbbca0ecdd2ac3a9ed74f353a 424 PIRSF PIRSF500134 1 424 1.9E-151 T 11-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 AFK25_03605 e345517fbbca0ecdd2ac3a9ed74f353a 424 PIRSF PIRSF000124 1 423 5.3E-135 T 11-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFK25_03605 e345517fbbca0ecdd2ac3a9ed74f353a 424 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 197 287 2.2E-36 T 11-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFK25_03605 e345517fbbca0ecdd2ac3a9ed74f353a 424 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 310 406 2.8E-29 T 11-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFK25_03605 e345517fbbca0ecdd2ac3a9ed74f353a 424 SUPERFAMILY SSF48179 197 289 3.4E-30 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFK25_03605 e345517fbbca0ecdd2ac3a9ed74f353a 424 Gene3D G3DSA:1.20.5.100 194 224 4.6E-18 T 11-10-2018 AFK25_03605 e345517fbbca0ecdd2ac3a9ed74f353a 424 SUPERFAMILY SSF52413 296 418 1.57E-33 T 11-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 AFK25_03605 e345517fbbca0ecdd2ac3a9ed74f353a 424 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 173 9.7E-62 T 11-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFK25_03605 e345517fbbca0ecdd2ac3a9ed74f353a 424 SMART SM00984 310 408 1.7E-40 T 11-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFK25_03605 e345517fbbca0ecdd2ac3a9ed74f353a 424 Gene3D G3DSA:3.40.50.720 1 191 3.4E-70 T 11-10-2018 AFK25_01810 6b29116971b38654d5b51a131a972e7c 255 Gene3D G3DSA:3.20.20.370 11 245 4.3E-87 T 11-10-2018 AFK25_01810 6b29116971b38654d5b51a131a972e7c 255 TIGRFAM TIGR02884 spore_pdaA: delta-lactam-biosynthetic de-N-acetylase 20 242 1.6E-110 T 11-10-2018 IPR014235 Peptidoglycan-N-acetylmuramic acid deacetylase PdaA AFK25_01810 6b29116971b38654d5b51a131a972e7c 255 SUPERFAMILY SSF88713 43 241 6.9E-68 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFK25_01810 6b29116971b38654d5b51a131a972e7c 255 Pfam PF01522 Polysaccharide deacetylase 51 172 1.3E-34 T 11-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFK25_04980 fb036ef51a4585ef5bd085e5a8efc41b 443 SUPERFAMILY SSF52540 23 423 4.3E-27 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_04980 fb036ef51a4585ef5bd085e5a8efc41b 443 SMART SM00670 4 136 6.6E-25 T 11-10-2018 IPR002716 PIN domain AFK25_04980 fb036ef51a4585ef5bd085e5a8efc41b 443 Pfam PF13638 PIN domain 6 148 5.0E-33 T 11-10-2018 IPR002716 PIN domain AFK25_04980 fb036ef51a4585ef5bd085e5a8efc41b 443 Gene3D G3DSA:3.40.50.300 232 442 3.4E-69 T 11-10-2018 AFK25_04980 fb036ef51a4585ef5bd085e5a8efc41b 443 Pfam PF02562 PhoH-like protein 234 437 3.2E-54 T 11-10-2018 IPR003714 PhoH-like protein GO:0005524 AFK25_04980 fb036ef51a4585ef5bd085e5a8efc41b 443 Gene3D G3DSA:3.40.50.1010 1 151 8.8E-22 T 11-10-2018 AFK25_01020 45b41f48ac8ef9d216ac53908e1ef7ea 70 Gene3D G3DSA:2.40.50.100 4 70 5.9E-24 T 11-10-2018 AFK25_01020 45b41f48ac8ef9d216ac53908e1ef7ea 70 SUPERFAMILY SSF51230 2 70 5.63E-22 T 11-10-2018 IPR011053 Single hybrid motif AFK25_01020 45b41f48ac8ef9d216ac53908e1ef7ea 70 Pfam PF00364 Biotin-requiring enzyme 9 69 3.4E-17 T 11-10-2018 IPR000089 Biotin/lipoyl attachment AFK25_11795 79de915f277044d4f18544ca1813638d 524 Pfam PF13193 AMP-binding enzyme C-terminal domain 429 508 1.1E-23 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFK25_11795 79de915f277044d4f18544ca1813638d 524 Pfam PF00501 AMP-binding enzyme 19 420 2.0E-82 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFK25_11795 79de915f277044d4f18544ca1813638d 524 Gene3D G3DSA:3.30.300.310 416 523 2.3E-29 T 11-10-2018 AFK25_11795 79de915f277044d4f18544ca1813638d 524 ProSitePatterns PS00455 Putative AMP-binding domain signature. 172 183 - T 11-10-2018 IPR020845 AMP-binding, conserved site AFK25_11795 79de915f277044d4f18544ca1813638d 524 SUPERFAMILY SSF56801 19 520 2.22E-141 T 11-10-2018 AFK25_11795 79de915f277044d4f18544ca1813638d 524 Gene3D G3DSA:3.40.50.12780 2 413 3.7E-112 T 11-10-2018 AFK25_13360 10d2f5e40390bbcdd259fdb8204655b7 443 Gene3D G3DSA:1.20.1600.10 165 333 1.6E-11 T 11-10-2018 AFK25_13360 10d2f5e40390bbcdd259fdb8204655b7 443 SUPERFAMILY SSF56954 169 431 6.15E-13 T 11-10-2018 AFK25_04520 3ded9532a0b83cca22d95531d68a2dd5 145 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 17 139 2.7E-26 T 11-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 AFK25_04520 3ded9532a0b83cca22d95531d68a2dd5 145 Gene3D G3DSA:3.30.479.10 7 141 1.5E-27 T 11-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 AFK25_04520 3ded9532a0b83cca22d95531d68a2dd5 145 PIRSF PIRSF006113 13 141 3.7E-18 T 11-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 AFK25_04520 3ded9532a0b83cca22d95531d68a2dd5 145 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 16 111 1.6E-26 T 11-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 AFK25_04520 3ded9532a0b83cca22d95531d68a2dd5 145 SUPERFAMILY SSF55620 11 139 3.06E-31 T 11-10-2018 AFK25_06015 b6830e16d43b52f982fea4afee182585 517 Hamap MF_00733 1-pyrroline-5-carboxylate dehydrogenase [rocA]. 3 517 66.594 T 11-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 AFK25_06015 b6830e16d43b52f982fea4afee182585 517 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 287 294 - T 11-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 AFK25_06015 b6830e16d43b52f982fea4afee182585 517 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 315 326 - T 11-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 AFK25_06015 b6830e16d43b52f982fea4afee182585 517 Pfam PF00171 Aldehyde dehydrogenase family 52 513 1.6E-157 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFK25_06015 b6830e16d43b52f982fea4afee182585 517 Gene3D G3DSA:3.40.605.10 12 513 3.1E-191 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFK25_06015 b6830e16d43b52f982fea4afee182585 517 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 7 517 6.6E-253 T 11-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 AFK25_06015 b6830e16d43b52f982fea4afee182585 517 SUPERFAMILY SSF53720 5 513 6.94E-158 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFK25_06015 b6830e16d43b52f982fea4afee182585 517 Gene3D G3DSA:3.40.309.10 292 482 3.1E-191 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFK25_11690 4cc1a76b54546f8c64712715f1e08dae 436 Gene3D G3DSA:3.10.129.10 326 435 1.6E-10 T 11-10-2018 AFK25_11690 4cc1a76b54546f8c64712715f1e08dae 436 Pfam PF00571 CBS domain 254 308 5.6E-9 T 11-10-2018 IPR000644 CBS domain AFK25_11690 4cc1a76b54546f8c64712715f1e08dae 436 Pfam PF00571 CBS domain 219 247 0.0052 T 11-10-2018 IPR000644 CBS domain AFK25_11690 4cc1a76b54546f8c64712715f1e08dae 436 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 59 1.3E-6 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_11690 4cc1a76b54546f8c64712715f1e08dae 436 Pfam PF07085 DRTGG domain 77 179 2.1E-31 T 11-10-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFK25_11690 4cc1a76b54546f8c64712715f1e08dae 436 Gene3D G3DSA:1.10.10.10 6 70 2.3E-7 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_11690 4cc1a76b54546f8c64712715f1e08dae 436 SUPERFAMILY SSF75138 73 186 3.4E-29 T 11-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily AFK25_11690 4cc1a76b54546f8c64712715f1e08dae 436 SMART SM00116 201 249 0.068 T 11-10-2018 IPR000644 CBS domain AFK25_11690 4cc1a76b54546f8c64712715f1e08dae 436 SMART SM00116 260 308 2.0E-8 T 11-10-2018 IPR000644 CBS domain AFK25_11690 4cc1a76b54546f8c64712715f1e08dae 436 SUPERFAMILY SSF54631 183 308 5.94E-30 T 11-10-2018 AFK25_11690 4cc1a76b54546f8c64712715f1e08dae 436 Gene3D G3DSA:3.10.580.10 187 315 2.0E-24 T 11-10-2018 AFK25_11690 4cc1a76b54546f8c64712715f1e08dae 436 SUPERFAMILY SSF54637 337 433 4.05E-19 T 11-10-2018 IPR029069 HotDog domain superfamily AFK25_11690 4cc1a76b54546f8c64712715f1e08dae 436 Pfam PF03061 Thioesterase superfamily 350 423 2.8E-11 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFK25_11690 4cc1a76b54546f8c64712715f1e08dae 436 Gene3D G3DSA:3.40.1390.20 71 179 2.9E-27 T 11-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily AFK25_11690 4cc1a76b54546f8c64712715f1e08dae 436 SUPERFAMILY SSF46785 6 55 4.77E-8 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_11755 1f9ba9ffa5fbbbd6fa5d2ffca5a03c0d 267 Gene3D G3DSA:3.40.50.10330 33 267 3.5E-75 T 11-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 AFK25_11755 1f9ba9ffa5fbbbd6fa5d2ffca5a03c0d 267 Hamap MF_00361 NAD kinase [nadK]. 6 267 20.631 T 11-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFK25_11755 1f9ba9ffa5fbbbd6fa5d2ffca5a03c0d 267 Pfam PF01513 ATP-NAD kinase 39 244 1.0E-16 T 11-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFK25_11755 1f9ba9ffa5fbbbd6fa5d2ffca5a03c0d 267 SUPERFAMILY SSF111331 9 266 1.57E-59 T 11-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily AFK25_11755 1f9ba9ffa5fbbbd6fa5d2ffca5a03c0d 267 Gene3D G3DSA:2.60.200.30 109 245 3.5E-75 T 11-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFK25_11375 f2ce42c2320bf4b4a880f4c3122e3f65 344 Gene3D G3DSA:3.30.930.10 8 344 4.9E-129 T 11-10-2018 AFK25_11375 f2ce42c2320bf4b4a880f4c3122e3f65 344 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 40 342 2.6E-117 T 11-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AFK25_11375 f2ce42c2320bf4b4a880f4c3122e3f65 344 Pfam PF01409 tRNA synthetases class II core domain (F) 93 341 5.8E-111 T 11-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 AFK25_11375 f2ce42c2320bf4b4a880f4c3122e3f65 344 SUPERFAMILY SSF55681 93 342 8.9E-84 T 11-10-2018 AFK25_11375 f2ce42c2320bf4b4a880f4c3122e3f65 344 Hamap MF_00281 Phenylalanine--tRNA ligase alpha subunit [pheS]. 9 341 50.369 T 11-10-2018 IPR022911 Phenylalanine-tRNA ligase alpha chain 1, bacterial GO:0004826 KEGG: 00970+6.1.1.20 AFK25_11375 f2ce42c2320bf4b4a880f4c3122e3f65 344 Pfam PF02912 Aminoacyl tRNA synthetase class II, N-terminal domain 20 88 3.4E-28 T 11-10-2018 IPR004188 Phenylalanine-tRNA ligase, class II, N-terminal GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20 AFK25_11375 f2ce42c2320bf4b4a880f4c3122e3f65 344 SUPERFAMILY SSF46589 13 100 7.32E-24 T 11-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 AFK25_00105 b3478ef17704e7ca3e9f1fbc81b8ffa7 222 Pfam PF01712 Deoxynucleoside kinase 15 212 2.9E-64 T 11-10-2018 IPR031314 Deoxynucleoside kinase domain AFK25_00105 b3478ef17704e7ca3e9f1fbc81b8ffa7 222 Gene3D G3DSA:3.40.50.300 12 217 6.2E-59 T 11-10-2018 AFK25_00105 b3478ef17704e7ca3e9f1fbc81b8ffa7 222 SUPERFAMILY SSF52540 14 213 2.37E-48 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_00105 b3478ef17704e7ca3e9f1fbc81b8ffa7 222 PIRSF PIRSF000705 2 221 1.6E-64 T 11-10-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 AFK25_01510 2ae3fd92d9bf4e5fd11e49b9ac38f660 492 Pfam PF13408 Recombinase zinc beta ribbon domain 294 349 4.5E-12 T 11-10-2018 IPR025827 Recombinase zinc beta ribbon domain AFK25_01510 2ae3fd92d9bf4e5fd11e49b9ac38f660 492 SUPERFAMILY SSF53041 1 148 2.88E-31 T 11-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 AFK25_01510 2ae3fd92d9bf4e5fd11e49b9ac38f660 492 Pfam PF14287 Domain of unknown function (DUF4368) 439 476 2.2E-6 T 11-10-2018 IPR025378 Domain of unknown function DUF4368 AFK25_01510 2ae3fd92d9bf4e5fd11e49b9ac38f660 492 Gene3D G3DSA:3.40.50.1390 1 130 6.8E-31 T 11-10-2018 AFK25_01510 2ae3fd92d9bf4e5fd11e49b9ac38f660 492 SMART SM00857 3 148 1.1E-44 T 11-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFK25_01510 2ae3fd92d9bf4e5fd11e49b9ac38f660 492 Pfam PF00239 Resolvase, N terminal domain 5 147 3.1E-32 T 11-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFK25_01510 2ae3fd92d9bf4e5fd11e49b9ac38f660 492 Gene3D G3DSA:1.10.10.2600 132 285 1.4E-17 T 11-10-2018 IPR038109 DNA-binding recombinase domain superfamily AFK25_01510 2ae3fd92d9bf4e5fd11e49b9ac38f660 492 Pfam PF07508 Recombinase 170 282 3.3E-25 T 11-10-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 AFK25_05510 25390045e9d84a265fd3087c5c59f35d 313 SUPERFAMILY SSF55048 129 193 1.57E-16 T 11-10-2018 IPR016036 Malonyl-CoA ACP transacylase, ACP-binding AFK25_05510 25390045e9d84a265fd3087c5c59f35d 313 SMART SM00827 Acyl transferase domain in polyketide synthase (PKS) enzymes. 7 313 4.1E-47 T 11-10-2018 IPR020801 Polyketide synthase, acyl transferase domain AFK25_05510 25390045e9d84a265fd3087c5c59f35d 313 TIGRFAM TIGR00128 fabD: malonyl CoA-acyl carrier protein transacylase 3 290 6.0E-118 T 11-10-2018 IPR004410 Malonyl CoA-acyl carrier protein transacylase, FabD-type GO:0004314 KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 AFK25_05510 25390045e9d84a265fd3087c5c59f35d 313 SUPERFAMILY SSF52151 4 308 1.52E-80 T 11-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase AFK25_05510 25390045e9d84a265fd3087c5c59f35d 313 Gene3D G3DSA:3.30.70.250 127 197 9.7E-102 T 11-10-2018 AFK25_05510 25390045e9d84a265fd3087c5c59f35d 313 Gene3D G3DSA:3.40.366.10 5 287 9.7E-102 T 11-10-2018 IPR001227 Acyl transferase domain superfamily GO:0016740 AFK25_05510 25390045e9d84a265fd3087c5c59f35d 313 Pfam PF00698 Acyl transferase domain 6 286 2.6E-42 T 11-10-2018 IPR014043 Acyl transferase AFK25_05510 25390045e9d84a265fd3087c5c59f35d 313 PIRSF PIRSF000446 1 311 1.8E-123 T 11-10-2018 IPR024925 Malonyl CoA-acyl carrier protein transacylase KEGG: 00061+2.3.1.39|MetaCyc: PWY-4381|MetaCyc: PWY-6799|MetaCyc: PWY-7388 AFK25_12625 8f956b71c44ddd0d1c26e9fa271091ae 433 SUPERFAMILY SSF55347 138 303 1.18E-53 T 11-10-2018 AFK25_12625 8f956b71c44ddd0d1c26e9fa271091ae 433 Pfam PF01842 ACT domain 350 416 8.3E-12 T 11-10-2018 IPR002912 ACT domain AFK25_12625 8f956b71c44ddd0d1c26e9fa271091ae 433 SUPERFAMILY SSF55021 349 422 2.93E-12 T 11-10-2018 AFK25_12625 8f956b71c44ddd0d1c26e9fa271091ae 433 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 184 206 - T 11-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AFK25_12625 8f956b71c44ddd0d1c26e9fa271091ae 433 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 11 130 6.5E-27 T 11-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 AFK25_12625 8f956b71c44ddd0d1c26e9fa271091ae 433 Gene3D G3DSA:3.30.360.10 137 344 6.1E-154 T 11-10-2018 AFK25_12625 8f956b71c44ddd0d1c26e9fa271091ae 433 Pfam PF00742 Homoserine dehydrogenase 138 316 3.3E-66 T 11-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AFK25_12625 8f956b71c44ddd0d1c26e9fa271091ae 433 Gene3D G3DSA:3.30.70.260 345 418 6.1E-154 T 11-10-2018 AFK25_12625 8f956b71c44ddd0d1c26e9fa271091ae 433 Gene3D G3DSA:3.40.50.720 5 341 6.1E-154 T 11-10-2018 AFK25_12625 8f956b71c44ddd0d1c26e9fa271091ae 433 PIRSF PIRSF000098 2 430 2.0E-175 T 11-10-2018 IPR016204 Homoserine dehydrogenase GO:0004412|GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AFK25_12625 8f956b71c44ddd0d1c26e9fa271091ae 433 SUPERFAMILY SSF51735 2 159 1.5E-37 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_09730 1bc7d0edcaf723868c082b3297d9219a 366 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 56 360 2.0E-103 T 11-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFK25_09730 1bc7d0edcaf723868c082b3297d9219a 366 Pfam PF03308 ArgK protein 60 330 1.9E-106 T 11-10-2018 AFK25_09730 1bc7d0edcaf723868c082b3297d9219a 366 Gene3D G3DSA:1.10.287.130 301 366 1.0E-19 T 11-10-2018 AFK25_09730 1bc7d0edcaf723868c082b3297d9219a 366 Gene3D G3DSA:3.40.50.300 89 299 8.8E-80 T 11-10-2018 AFK25_09730 1bc7d0edcaf723868c082b3297d9219a 366 Gene3D G3DSA:1.20.5.170 37 88 1.7E-14 T 11-10-2018 AFK25_09730 1bc7d0edcaf723868c082b3297d9219a 366 SUPERFAMILY SSF52540 44 363 1.34E-93 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_10560 37e5b1c1b6a3497116322010a028ce36 235 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 3 43 1.3E-15 T 11-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal AFK25_10560 37e5b1c1b6a3497116322010a028ce36 235 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 4 161 1.4E-14 T 11-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 AFK25_10560 37e5b1c1b6a3497116322010a028ce36 235 TIGRFAM TIGR01895 cas_Cas5t: CRISPR-associated protein Cas5, subtype I-B/TNEAP 1 215 9.1E-39 T 11-10-2018 IPR013337 CRISPR-associated protein Cas5, Tneap type AFK25_03945 6ca481329a6cc16de8cd886ae7323113 984 Gene3D G3DSA:3.40.50.300 267 451 3.3E-57 T 11-10-2018 AFK25_03945 6ca481329a6cc16de8cd886ae7323113 984 Pfam PF11867 Domain of unknown function (DUF3387) 719 978 1.8E-32 T 11-10-2018 IPR021810 Protein of unknown function DUF3387 AFK25_03945 6ca481329a6cc16de8cd886ae7323113 984 SUPERFAMILY SSF52540 292 716 2.34E-13 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_03945 6ca481329a6cc16de8cd886ae7323113 984 SUPERFAMILY SSF52540 230 484 3.16E-29 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_03945 6ca481329a6cc16de8cd886ae7323113 984 Gene3D G3DSA:3.90.1570.50 81 260 3.4E-29 T 11-10-2018 AFK25_03945 6ca481329a6cc16de8cd886ae7323113 984 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 12 682 4.7E-186 T 11-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 AFK25_03945 6ca481329a6cc16de8cd886ae7323113 984 SMART SM00487 263 466 9.3E-11 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFK25_03945 6ca481329a6cc16de8cd886ae7323113 984 Gene3D G3DSA:3.40.50.300 452 683 3.3E-41 T 11-10-2018 AFK25_03945 6ca481329a6cc16de8cd886ae7323113 984 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 8 204 2.4E-41 T 11-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 AFK25_03945 6ca481329a6cc16de8cd886ae7323113 984 Pfam PF04851 Type III restriction enzyme, res subunit 269 433 5.3E-19 T 11-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFK25_11430 c17226405073d705e67566d51a53f33b 241 Gene3D G3DSA:3.40.50.2300 1 118 3.6E-30 T 11-10-2018 AFK25_11430 c17226405073d705e67566d51a53f33b 241 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 216 232 4.7E-5 T 11-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFK25_11430 c17226405073d705e67566d51a53f33b 241 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 201 216 4.7E-5 T 11-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFK25_11430 c17226405073d705e67566d51a53f33b 241 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 186 228 - T 11-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFK25_11430 c17226405073d705e67566d51a53f33b 241 Gene3D G3DSA:1.10.10.60 182 238 1.6E-18 T 11-10-2018 AFK25_11430 c17226405073d705e67566d51a53f33b 241 SMART SM00342 149 232 1.0E-28 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFK25_11430 c17226405073d705e67566d51a53f33b 241 Gene3D G3DSA:1.10.10.60 129 181 2.6E-19 T 11-10-2018 AFK25_11430 c17226405073d705e67566d51a53f33b 241 Pfam PF00072 Response regulator receiver domain 11 100 6.0E-25 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_11430 c17226405073d705e67566d51a53f33b 241 SUPERFAMILY SSF46689 134 183 2.11E-9 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_11430 c17226405073d705e67566d51a53f33b 241 SUPERFAMILY SSF52172 13 111 1.28E-29 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_11430 c17226405073d705e67566d51a53f33b 241 SUPERFAMILY SSF46689 185 236 1.03E-12 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_11430 c17226405073d705e67566d51a53f33b 241 Pfam PF12833 Helix-turn-helix domain 157 233 6.0E-19 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFK25_11430 c17226405073d705e67566d51a53f33b 241 SMART SM00448 1 99 8.6E-18 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_10750 7f88ac1ca7268f45e24db40da7639bcc 423 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 4 410 1.8E-161 T 11-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 AFK25_10750 7f88ac1ca7268f45e24db40da7639bcc 423 SUPERFAMILY SSF55681 3 318 3.45E-102 T 11-10-2018 AFK25_10750 7f88ac1ca7268f45e24db40da7639bcc 423 Pfam PF13393 Histidyl-tRNA synthetase 8 313 3.9E-51 T 11-10-2018 AFK25_10750 7f88ac1ca7268f45e24db40da7639bcc 423 Gene3D G3DSA:3.40.50.800 328 422 4.8E-28 T 11-10-2018 IPR036621 Anticodon-binding domain superfamily AFK25_10750 7f88ac1ca7268f45e24db40da7639bcc 423 SUPERFAMILY SSF52954 329 422 6.8E-26 T 11-10-2018 AFK25_10750 7f88ac1ca7268f45e24db40da7639bcc 423 PIRSF PIRSF001549 1 422 2.1E-123 T 11-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 AFK25_10750 7f88ac1ca7268f45e24db40da7639bcc 423 Gene3D G3DSA:3.30.930.10 2 324 2.5E-119 T 11-10-2018 AFK25_10750 7f88ac1ca7268f45e24db40da7639bcc 423 Pfam PF03129 Anticodon binding domain 331 418 3.0E-16 T 11-10-2018 IPR004154 Anticodon-binding AFK25_10750 7f88ac1ca7268f45e24db40da7639bcc 423 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 420 34.839 T 11-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 AFK25_11875 524575327166846920ae0385f4579f6f 333 SMART SM00354 2 72 7.8E-39 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_11875 524575327166846920ae0385f4579f6f 333 Gene3D G3DSA:3.40.50.2300 63 310 1.5E-94 T 11-10-2018 AFK25_11875 524575327166846920ae0385f4579f6f 333 TIGRFAM TIGR01481 ccpA: catabolite control protein A 1 332 1.5E-163 T 11-10-2018 IPR006377 Catabolite control protein A GO:0006355 AFK25_11875 524575327166846920ae0385f4579f6f 333 Gene3D G3DSA:3.40.50.2300 161 291 1.5E-94 T 11-10-2018 AFK25_11875 524575327166846920ae0385f4579f6f 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 14 24 4.4E-6 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_11875 524575327166846920ae0385f4579f6f 333 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 4 14 4.4E-6 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_11875 524575327166846920ae0385f4579f6f 333 SUPERFAMILY SSF47413 2 60 7.82E-20 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFK25_11875 524575327166846920ae0385f4579f6f 333 Gene3D G3DSA:1.10.260.40 1 60 2.6E-29 T 11-10-2018 AFK25_11875 524575327166846920ae0385f4579f6f 333 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 1.2E-19 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_11875 524575327166846920ae0385f4579f6f 333 Pfam PF13377 Periplasmic binding protein-like domain 170 331 9.8E-37 T 11-10-2018 AFK25_11875 524575327166846920ae0385f4579f6f 333 ProSitePatterns PS00356 LacI-type HTH domain signature. 5 23 - T 11-10-2018 AFK25_11875 524575327166846920ae0385f4579f6f 333 SUPERFAMILY SSF53822 62 332 7.43E-92 T 11-10-2018 IPR028082 Periplasmic binding protein-like I AFK25_07885 55f9d2becd6005807a8d201d2d4c45de 308 SUPERFAMILY SSF56281 47 274 3.41E-35 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_07885 55f9d2becd6005807a8d201d2d4c45de 308 PIRSF PIRSF038896 5 307 2.4E-94 T 11-10-2018 IPR024884 N-acyl-phosphatidylethanolamine-hydrolysing phospholipase D GO:0008270|GO:0070290 Reactome: R-HSA-2466712 AFK25_07885 55f9d2becd6005807a8d201d2d4c45de 308 Gene3D G3DSA:3.60.15.10 52 303 1.4E-83 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_07885 55f9d2becd6005807a8d201d2d4c45de 308 Pfam PF12706 Beta-lactamase superfamily domain 74 262 5.8E-38 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_12485 233b040e4c30390f4300908f7680aa1e 449 Gene3D G3DSA:3.40.50.10490 43 224 6.1E-77 T 11-10-2018 AFK25_12485 233b040e4c30390f4300908f7680aa1e 449 Gene3D G3DSA:3.40.50.10490 225 417 1.7E-85 T 11-10-2018 AFK25_12485 233b040e4c30390f4300908f7680aa1e 449 Gene3D G3DSA:3.40.50.10490 1 42 1.7E-18 T 11-10-2018 AFK25_12485 233b040e4c30390f4300908f7680aa1e 449 SUPERFAMILY SSF53697 4 447 1.24E-147 T 11-10-2018 AFK25_12485 233b040e4c30390f4300908f7680aa1e 449 Hamap MF_00473 Glucose-6-phosphate isomerase [pgi]. 1 435 27.353 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12485 233b040e4c30390f4300908f7680aa1e 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 198 216 1.0E-28 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12485 233b040e4c30390f4300908f7680aa1e 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 394 408 1.0E-28 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12485 233b040e4c30390f4300908f7680aa1e 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 408 421 1.0E-28 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12485 233b040e4c30390f4300908f7680aa1e 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 376 394 1.0E-28 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12485 233b040e4c30390f4300908f7680aa1e 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 273 294 1.0E-28 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12485 233b040e4c30390f4300908f7680aa1e 449 PRINTS PR00662 Glucose-6-phosphate isomerase signature 76 95 1.0E-28 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12485 233b040e4c30390f4300908f7680aa1e 449 ProSitePatterns PS00765 Phosphoglucose isomerase signature 1. 202 215 - T 11-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12485 233b040e4c30390f4300908f7680aa1e 449 ProSitePatterns PS00174 Phosphoglucose isomerase signature 2. 408 425 - T 11-10-2018 IPR018189 Phosphoglucose isomerase, conserved site GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12485 233b040e4c30390f4300908f7680aa1e 449 Pfam PF00342 Phosphoglucose isomerase 76 295 4.8E-21 T 11-10-2018 IPR001672 Phosphoglucose isomerase (PGI) GO:0004347|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385|Reactome: R-HSA-5628897|Reactome: R-HSA-6798695|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_00720 5ec222f417cd5788b9eb8dbd56a10c54 72 Pfam PF01176 Translation initiation factor 1A / IF-1 7 70 1.6E-29 T 11-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 AFK25_00720 5ec222f417cd5788b9eb8dbd56a10c54 72 TIGRFAM TIGR00008 infA: translation initiation factor IF-1 3 71 2.6E-40 T 11-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 AFK25_00720 5ec222f417cd5788b9eb8dbd56a10c54 72 Gene3D G3DSA:2.40.50.140 1 72 5.5E-39 T 11-10-2018 AFK25_00720 5ec222f417cd5788b9eb8dbd56a10c54 72 Hamap MF_00075 Translation initiation factor IF-1 [infA]. 1 72 28.649 T 11-10-2018 IPR004368 Translation initiation factor IF-1 GO:0003743|GO:0006413 AFK25_00720 5ec222f417cd5788b9eb8dbd56a10c54 72 SMART SM00316 4 72 3.3E-7 T 11-10-2018 IPR022967 RNA-binding domain, S1 AFK25_00720 5ec222f417cd5788b9eb8dbd56a10c54 72 SUPERFAMILY SSF50249 1 71 1.47E-29 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_13630 5e15ac372360644ee55031fea794e016 899 Pfam PF00271 Helicase conserved C-terminal domain 731 843 1.3E-21 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_13630 5e15ac372360644ee55031fea794e016 899 Gene3D G3DSA:3.40.50.300 655 857 3.6E-89 T 11-10-2018 AFK25_13630 5e15ac372360644ee55031fea794e016 899 SUPERFAMILY SSF52540 648 898 3.76E-67 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_13630 5e15ac372360644ee55031fea794e016 899 SMART SM00487 427 614 7.8E-36 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFK25_13630 5e15ac372360644ee55031fea794e016 899 Gene3D G3DSA:1.20.120.850 669 892 3.6E-89 T 11-10-2018 AFK25_13630 5e15ac372360644ee55031fea794e016 899 Gene3D G3DSA:3.40.50.10810 432 646 7.4E-74 T 11-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily AFK25_13630 5e15ac372360644ee55031fea794e016 899 SUPERFAMILY SSF52540 396 645 1.82E-63 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_13630 5e15ac372360644ee55031fea794e016 899 SMART SM00490 760 843 9.4E-22 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_13630 5e15ac372360644ee55031fea794e016 899 Pfam PF00176 SNF2 family N-terminal domain 443 715 1.3E-61 T 11-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 AFK25_13630 5e15ac372360644ee55031fea794e016 899 Pfam PF12419 SNF2 Helicase protein 257 382 1.5E-37 T 11-10-2018 IPR022138 Helicase SWF/SNF-related AFK25_08870 9ee23276ce16bb89500699014542b7c0 367 Pfam PF01842 ACT domain 298 336 8.2E-7 T 11-10-2018 IPR002912 ACT domain AFK25_08870 9ee23276ce16bb89500699014542b7c0 367 SUPERFAMILY SSF51735 5 171 3.95E-44 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_08870 9ee23276ce16bb89500699014542b7c0 367 Gene3D G3DSA:1.10.3660.10 182 296 4.7E-37 T 11-10-2018 AFK25_08870 9ee23276ce16bb89500699014542b7c0 367 SUPERFAMILY SSF48179 175 284 3.83E-36 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFK25_08870 9ee23276ce16bb89500699014542b7c0 367 SUPERFAMILY SSF55021 290 358 8.09E-9 T 11-10-2018 AFK25_08870 9ee23276ce16bb89500699014542b7c0 367 Pfam PF02153 Prephenate dehydrogenase 17 275 1.3E-84 T 11-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 AFK25_08870 9ee23276ce16bb89500699014542b7c0 367 Gene3D G3DSA:3.40.50.720 2 181 9.0E-55 T 11-10-2018 AFK25_01050 23d6b63ab625eb7b783bb9abfff29acd 370 Pfam PF06925 Monogalactosyldiacylglycerol (MGDG) synthase 16 181 3.2E-28 T 11-10-2018 IPR009695 Diacylglycerol glucosyltransferase, N-terminal GO:0009247|GO:0016758 AFK25_01050 23d6b63ab625eb7b783bb9abfff29acd 370 SUPERFAMILY SSF53756 59 347 2.89E-24 T 11-10-2018 AFK25_01050 23d6b63ab625eb7b783bb9abfff29acd 370 Gene3D G3DSA:3.40.50.2000 183 344 4.7E-20 T 11-10-2018 AFK25_01110 07b7b536fcf5402aedadc240d7497232 713 Gene3D G3DSA:1.10.10.650 1 99 1.9E-38 T 11-10-2018 IPR023319 Tex-like protein, HTH domain superfamily AFK25_01110 07b7b536fcf5402aedadc240d7497232 713 Gene3D G3DSA:2.40.50.140 618 705 1.6E-25 T 11-10-2018 AFK25_01110 07b7b536fcf5402aedadc240d7497232 713 SUPERFAMILY SSF53098 303 450 2.96E-51 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_01110 07b7b536fcf5402aedadc240d7497232 713 Pfam PF16921 Tex protein YqgF-like domain 307 432 7.6E-58 T 11-10-2018 IPR032639 Tex protein, YqgF-like domain AFK25_01110 07b7b536fcf5402aedadc240d7497232 713 Gene3D G3DSA:1.10.3500.10 102 479 4.4E-161 T 11-10-2018 IPR023323 Tex-like domain superfamily AFK25_01110 07b7b536fcf5402aedadc240d7497232 713 SUPERFAMILY SSF50249 619 705 1.42E-23 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_01110 07b7b536fcf5402aedadc240d7497232 713 SUPERFAMILY SSF47781 541 616 1.2E-15 T 11-10-2018 IPR010994 RuvA domain 2-like AFK25_01110 07b7b536fcf5402aedadc240d7497232 713 SMART SM00316 633 704 2.2E-23 T 11-10-2018 IPR022967 RNA-binding domain, S1 AFK25_01110 07b7b536fcf5402aedadc240d7497232 713 Gene3D G3DSA:1.10.150.310 480 614 1.3E-46 T 11-10-2018 AFK25_01110 07b7b536fcf5402aedadc240d7497232 713 Pfam PF00575 S1 RNA binding domain 632 703 1.3E-18 T 11-10-2018 IPR003029 S1 domain GO:0003676 AFK25_01110 07b7b536fcf5402aedadc240d7497232 713 SUPERFAMILY SSF47781 451 537 6.67E-27 T 11-10-2018 IPR010994 RuvA domain 2-like AFK25_01110 07b7b536fcf5402aedadc240d7497232 713 SUPERFAMILY SSF158832 2 302 1.57E-114 T 11-10-2018 AFK25_01110 07b7b536fcf5402aedadc240d7497232 713 Gene3D G3DSA:3.30.420.140 306 432 4.4E-161 T 11-10-2018 IPR037027 YqgF/RNase H-like domain superfamily GO:0006139 AFK25_01110 07b7b536fcf5402aedadc240d7497232 713 Pfam PF12836 Helix-hairpin-helix motif 472 536 5.2E-27 T 11-10-2018 AFK25_01110 07b7b536fcf5402aedadc240d7497232 713 Pfam PF09371 Tex-like protein N-terminal domain 3 181 2.3E-71 T 11-10-2018 IPR018974 Tex-like protein, N-terminal AFK25_01110 07b7b536fcf5402aedadc240d7497232 713 SMART SM00732 307 405 1.2E-35 T 11-10-2018 IPR006641 YqgF/RNase H-like domain GO:0006139 AFK25_07890 f01b6981fbb8ef95b2d54d7bf1a1eb91 588 SMART SM00382 369 561 7.3E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_07890 f01b6981fbb8ef95b2d54d7bf1a1eb91 588 Pfam PF00664 ABC transporter transmembrane region 25 298 8.6E-41 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFK25_07890 f01b6981fbb8ef95b2d54d7bf1a1eb91 588 ProSitePatterns PS00211 ABC transporters family signature. 481 495 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_07890 f01b6981fbb8ef95b2d54d7bf1a1eb91 588 SUPERFAMILY SSF52540 336 579 3.62E-89 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_07890 f01b6981fbb8ef95b2d54d7bf1a1eb91 588 SUPERFAMILY SSF90123 13 330 8.5E-71 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFK25_07890 f01b6981fbb8ef95b2d54d7bf1a1eb91 588 Pfam PF00005 ABC transporter 360 509 1.0E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_07890 f01b6981fbb8ef95b2d54d7bf1a1eb91 588 Gene3D G3DSA:1.20.1560.10 1 331 1.7E-77 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFK25_07890 f01b6981fbb8ef95b2d54d7bf1a1eb91 588 Gene3D G3DSA:3.40.50.300 340 586 2.3E-91 T 11-10-2018 AFK25_08935 9c013a748f55d5da4f3122f06e59ae6c 320 SUPERFAMILY SSF48576 5 320 3.06E-86 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFK25_08935 9c013a748f55d5da4f3122f06e59ae6c 320 TIGRFAM TIGR02748 GerC3_HepT: heptaprenyl diphosphate synthase component II 2 320 5.4E-161 T 11-10-2018 IPR014119 Heptaprenyl diphosphate synthase component II KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 AFK25_08935 9c013a748f55d5da4f3122f06e59ae6c 320 Gene3D G3DSA:1.10.600.10 7 320 3.9E-100 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFK25_08935 9c013a748f55d5da4f3122f06e59ae6c 320 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 203 215 - T 11-10-2018 IPR033749 Polyprenyl synthetase, conserved site AFK25_08935 9c013a748f55d5da4f3122f06e59ae6c 320 Pfam PF00348 Polyprenyl synthetase 31 258 4.8E-68 T 11-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 AFK25_08935 9c013a748f55d5da4f3122f06e59ae6c 320 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 81 95 - T 11-10-2018 IPR033749 Polyprenyl synthetase, conserved site AFK25_08485 88e8b8c8e2ad9ec2588f9247e19f99f7 274 Pfam PF02673 Bacitracin resistance protein BacA 9 267 9.5E-80 T 11-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 AFK25_08485 88e8b8c8e2ad9ec2588f9247e19f99f7 274 TIGRFAM TIGR00753 undec_PP_bacA: undecaprenyl-diphosphatase UppP 9 265 1.0E-88 T 11-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 AFK25_08485 88e8b8c8e2ad9ec2588f9247e19f99f7 274 Hamap MF_01006 Undecaprenyl-diphosphatase [uppP]. 4 272 17.84 T 11-10-2018 IPR003824 Undecaprenyl-diphosphatase UppP GO:0016020|GO:0016311|GO:0050380 KEGG: 00550+3.6.1.27|MetaCyc: PWY-5785 AFK25_04510 df9958264d1a0a58d942489d3c19384f 219 Pfam PF01895 PhoU domain 19 106 7.2E-21 T 11-10-2018 IPR026022 PhoU domain AFK25_04510 df9958264d1a0a58d942489d3c19384f 219 Pfam PF01895 PhoU domain 122 205 2.1E-20 T 11-10-2018 IPR026022 PhoU domain AFK25_04510 df9958264d1a0a58d942489d3c19384f 219 SUPERFAMILY SSF109755 4 218 1.99E-66 T 11-10-2018 AFK25_04510 df9958264d1a0a58d942489d3c19384f 219 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 6 213 5.4E-64 T 11-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 AFK25_04510 df9958264d1a0a58d942489d3c19384f 219 Gene3D G3DSA:1.20.58.220 3 219 2.6E-71 T 11-10-2018 IPR038078 PhoU-like domain superfamily AFK25_04510 df9958264d1a0a58d942489d3c19384f 219 PIRSF PIRSF003107 1 219 1.5E-61 T 11-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 AFK25_01985 e29726e56e8c28869e01911e276e1326 139 Pfam PF07885 Ion channel 69 132 1.1E-13 T 11-10-2018 IPR013099 Potassium channel domain AFK25_01985 e29726e56e8c28869e01911e276e1326 139 SUPERFAMILY SSF81324 32 129 6.02E-13 T 11-10-2018 AFK25_01985 e29726e56e8c28869e01911e276e1326 139 Gene3D G3DSA:1.10.287.70 26 138 1.2E-14 T 11-10-2018 AFK25_07200 a5c1a9c4ce3a7f9beac6821adc415e89 454 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 407 453 4.0E-20 T 11-10-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain AFK25_07200 a5c1a9c4ce3a7f9beac6821adc415e89 454 Gene3D G3DSA:2.30.130.60 398 454 4.2E-24 T 11-10-2018 AFK25_07200 a5c1a9c4ce3a7f9beac6821adc415e89 454 Pfam PF17126 RsmF rRNA methyltransferase first C-terminal domain 330 390 2.5E-22 T 11-10-2018 IPR031340 Ribosomal RNA small subunit methyltransferase F, first C-terminal domain AFK25_07200 a5c1a9c4ce3a7f9beac6821adc415e89 454 Pfam PF01189 16S rRNA methyltransferase RsmB/F 97 302 4.8E-56 T 11-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 AFK25_07200 a5c1a9c4ce3a7f9beac6821adc415e89 454 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 37 303 9.2E-77 T 11-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 AFK25_07200 a5c1a9c4ce3a7f9beac6821adc415e89 454 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 174 185 - T 11-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 AFK25_07200 a5c1a9c4ce3a7f9beac6821adc415e89 454 Gene3D G3DSA:3.30.70.3130 5 92 1.5E-32 T 11-10-2018 AFK25_07200 a5c1a9c4ce3a7f9beac6821adc415e89 454 Gene3D G3DSA:3.40.50.150 93 397 4.2E-106 T 11-10-2018 AFK25_07200 a5c1a9c4ce3a7f9beac6821adc415e89 454 SUPERFAMILY SSF53335 4 304 1.69E-69 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_07200 a5c1a9c4ce3a7f9beac6821adc415e89 454 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 6 93 9.5E-34 T 11-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 AFK25_07200 a5c1a9c4ce3a7f9beac6821adc415e89 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 175 187 2.1E-28 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFK25_07200 a5c1a9c4ce3a7f9beac6821adc415e89 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 225 241 2.1E-28 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFK25_07200 a5c1a9c4ce3a7f9beac6821adc415e89 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 79 93 2.1E-28 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFK25_07200 a5c1a9c4ce3a7f9beac6821adc415e89 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 286 303 2.1E-28 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFK25_07200 a5c1a9c4ce3a7f9beac6821adc415e89 454 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 108 118 2.1E-28 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFK25_13310 1dfa0db59d27acc517dc46f8858781ef 339 Pfam PF03816 Cell envelope-related transcriptional attenuator domain 96 243 1.0E-43 T 11-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain AFK25_13310 1dfa0db59d27acc517dc46f8858781ef 339 Gene3D G3DSA:1.10.260.150 54 339 2.8E-86 T 11-10-2018 AFK25_13310 1dfa0db59d27acc517dc46f8858781ef 339 TIGRFAM TIGR00350 lytR_cpsA_psr: cell envelope-related function transcriptional attenuator common domain 96 244 1.5E-39 T 11-10-2018 IPR004474 Cell envelope-related transcriptional attenuator domain AFK25_07625 117ed87df4c8dd0a0b662ec80b071cd4 329 TIGRFAM TIGR00433 bioB: biotin synthase 27 318 1.3E-119 T 11-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AFK25_07625 117ed87df4c8dd0a0b662ec80b071cd4 329 PIRSF PIRSF001619 1 326 3.6E-123 T 11-10-2018 IPR024177 Biotin synthase KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AFK25_07625 117ed87df4c8dd0a0b662ec80b071cd4 329 Gene3D G3DSA:3.20.20.70 15 321 1.0E-108 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_07625 117ed87df4c8dd0a0b662ec80b071cd4 329 Pfam PF04055 Radical SAM superfamily 64 219 4.2E-17 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFK25_07625 117ed87df4c8dd0a0b662ec80b071cd4 329 SUPERFAMILY SSF102114 13 320 4.32E-72 T 11-10-2018 AFK25_07625 117ed87df4c8dd0a0b662ec80b071cd4 329 Hamap MF_01694 Biotin synthase [bioB]. 14 321 40.791 T 11-10-2018 IPR002684 Biotin synthase/Biotin biosynthesis bifunctional protein BioAB GO:0004076|GO:0009102 KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AFK25_07625 117ed87df4c8dd0a0b662ec80b071cd4 329 SMART SM00729 54 262 1.5E-34 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFK25_07625 117ed87df4c8dd0a0b662ec80b071cd4 329 SMART SM00876 230 320 1.5E-34 T 11-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AFK25_07625 117ed87df4c8dd0a0b662ec80b071cd4 329 Pfam PF06968 Biotin and Thiamin Synthesis associated domain 230 318 1.9E-14 T 11-10-2018 IPR010722 Biotin and thiamin synthesis-associated domain KEGG: 00780+2.8.1.6|MetaCyc: PWY-7380 AFK25_03090 28a9234b423b8b13c720bef06c3578ff 530 Pfam PF00501 AMP-binding enzyme 12 424 2.8E-107 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFK25_03090 28a9234b423b8b13c720bef06c3578ff 530 SUPERFAMILY SSF56801 5 521 9.29E-154 T 11-10-2018 AFK25_03090 28a9234b423b8b13c720bef06c3578ff 530 Gene3D G3DSA:3.30.300.310 420 524 2.5E-36 T 11-10-2018 AFK25_03090 28a9234b423b8b13c720bef06c3578ff 530 ProSitePatterns PS00455 Putative AMP-binding domain signature. 168 179 - T 11-10-2018 IPR020845 AMP-binding, conserved site AFK25_03090 28a9234b423b8b13c720bef06c3578ff 530 Pfam PF13193 AMP-binding enzyme C-terminal domain 433 508 6.5E-22 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFK25_03090 28a9234b423b8b13c720bef06c3578ff 530 Gene3D G3DSA:3.40.50.12780 1 419 1.5E-125 T 11-10-2018 AFK25_10250 c4ce1e6caf51d38f035bd70cfaa44ddf 156 Pfam PF14181 YqfQ-like protein 25 156 9.4E-27 T 11-10-2018 IPR025571 YqfQ-like protein AFK25_08945 5f9120dd39b3868025c494e2413af271 216 Pfam PF07307 Heptaprenyl diphosphate synthase (HEPPP synthase) subunit 1 20 180 4.7E-51 T 11-10-2018 IPR009920 Heptaprenyl diphosphate synthase subunit 1 GO:0009234 KEGG: 00900+2.5.1.30|MetaCyc: PWY-5807 AFK25_05635 e47b6d2149338320ac2c9d9e492f6606 180 Hamap MF_00248 ATP-dependent protease subunit HslV [hslV]. 6 180 41.485 T 11-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 AFK25_05635 e47b6d2149338320ac2c9d9e492f6606 180 SUPERFAMILY SSF56235 3 179 3.26E-58 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFK25_05635 e47b6d2149338320ac2c9d9e492f6606 180 Gene3D G3DSA:3.60.20.10 2 180 6.8E-67 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFK25_05635 e47b6d2149338320ac2c9d9e492f6606 180 PIRSF PIRSF039093 1 180 2.5E-85 T 11-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 AFK25_05635 e47b6d2149338320ac2c9d9e492f6606 180 Pfam PF00227 Proteasome subunit 5 178 5.3E-26 T 11-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AFK25_05635 e47b6d2149338320ac2c9d9e492f6606 180 TIGRFAM TIGR03692 ATP_dep_HslV: ATP-dependent protease HslVU, peptidase subunit 7 180 3.3E-83 T 11-10-2018 IPR022281 ATP-dependent protease, HslV subunit GO:0004298|GO:0006508|GO:0009376 AFK25_00905 45ba576a2b1227c6550a6457d9eed195 600 Hamap MF_00164 Glutamine--fructose-6-phosphate aminotransferase [isomerizing] [glmS]. 1 600 39.141 T 11-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 AFK25_00905 45ba576a2b1227c6550a6457d9eed195 600 Pfam PF13522 Glutamine amidotransferase domain 62 191 1.1E-20 T 11-10-2018 AFK25_00905 45ba576a2b1227c6550a6457d9eed195 600 SUPERFAMILY SSF56235 2 235 2.92E-65 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFK25_00905 45ba576a2b1227c6550a6457d9eed195 600 Gene3D G3DSA:3.40.50.10490 444 600 7.1E-63 T 11-10-2018 AFK25_00905 45ba576a2b1227c6550a6457d9eed195 600 TIGRFAM TIGR01135 glmS: glutamine-fructose-6-phosphate transaminase (isomerizing) 2 600 2.5E-230 T 11-10-2018 IPR005855 Glucosamine-fructose-6-phosphate aminotransferase, isomerising GO:0004360|GO:1901137 KEGG: 00250+2.6.1.16|KEGG: 00520+2.6.1.16|MetaCyc: PWY-6749|Reactome: R-HSA-446210 AFK25_00905 45ba576a2b1227c6550a6457d9eed195 600 Gene3D G3DSA:3.40.50.10490 243 443 1.3E-64 T 11-10-2018 AFK25_00905 45ba576a2b1227c6550a6457d9eed195 600 Gene3D G3DSA:3.60.20.10 2 239 3.0E-70 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFK25_00905 45ba576a2b1227c6550a6457d9eed195 600 SUPERFAMILY SSF53697 244 600 1.39E-97 T 11-10-2018 AFK25_00905 45ba576a2b1227c6550a6457d9eed195 600 Pfam PF01380 SIS domain 289 414 1.5E-33 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFK25_00905 45ba576a2b1227c6550a6457d9eed195 600 Pfam PF01380 SIS domain 457 582 8.3E-16 T 11-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AFK25_07120 e59d7a484eb811603394f0f7e206d11b 158 TIGRFAM TIGR00140 hupD: hydrogenase expression/formation protein 6 154 2.1E-45 T 11-10-2018 IPR004419 Peptidase A31, hydrogenase expression/formation protein GO:0016485|GO:0046872 AFK25_07120 e59d7a484eb811603394f0f7e206d11b 158 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 8 150 1.3E-43 T 11-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFK25_07120 e59d7a484eb811603394f0f7e206d11b 158 SUPERFAMILY SSF53163 4 154 9.68E-42 T 11-10-2018 IPR023430 Peptidase HybD-like domain superfamily AFK25_07120 e59d7a484eb811603394f0f7e206d11b 158 PRINTS PR00446 Hydrogen uptake protein signature 59 69 9.5E-20 T 11-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFK25_07120 e59d7a484eb811603394f0f7e206d11b 158 PRINTS PR00446 Hydrogen uptake protein signature 18 29 9.5E-20 T 11-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFK25_07120 e59d7a484eb811603394f0f7e206d11b 158 PRINTS PR00446 Hydrogen uptake protein signature 38 55 9.5E-20 T 11-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFK25_07120 e59d7a484eb811603394f0f7e206d11b 158 PRINTS PR00446 Hydrogen uptake protein signature 70 86 9.5E-20 T 11-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFK25_07120 e59d7a484eb811603394f0f7e206d11b 158 PRINTS PR00446 Hydrogen uptake protein signature 6 18 9.5E-20 T 11-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFK25_07120 e59d7a484eb811603394f0f7e206d11b 158 Pfam PF01750 Hydrogenase maturation protease 24 149 3.6E-32 T 11-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AFK25_07120 e59d7a484eb811603394f0f7e206d11b 158 Gene3D G3DSA:3.40.50.1450 4 157 9.7E-41 T 11-10-2018 IPR023430 Peptidase HybD-like domain superfamily AFK25_14015 6cc78577ee66e30c2e455aef0ef35735 286 Gene3D G3DSA:1.10.1040.10 196 281 1.4E-36 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFK25_14015 6cc78577ee66e30c2e455aef0ef35735 286 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 189 285 6.5E-37 T 11-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFK25_14015 6cc78577ee66e30c2e455aef0ef35735 286 SUPERFAMILY SSF48179 188 286 6.04E-35 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFK25_14015 6cc78577ee66e30c2e455aef0ef35735 286 Gene3D G3DSA:3.40.50.720 5 191 2.7E-74 T 11-10-2018 AFK25_14015 6cc78577ee66e30c2e455aef0ef35735 286 SUPERFAMILY SSF51735 5 188 3.01E-63 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_14015 6cc78577ee66e30c2e455aef0ef35735 286 PIRSF PIRSF000105 3 286 1.0E-94 T 11-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 AFK25_14015 6cc78577ee66e30c2e455aef0ef35735 286 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 186 1.3E-69 T 11-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFK25_14015 6cc78577ee66e30c2e455aef0ef35735 286 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 186 211 - T 11-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AFK25_14665 ebecaa8c625441be4f785a355c6cfd47 44 ProSitePatterns PS00784 Ribosomal protein L34 signature. 2 21 - T 11-10-2018 IPR020939 Ribosomal protein L34, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_14665 ebecaa8c625441be4f785a355c6cfd47 44 Hamap MF_00391 50S ribosomal protein L34 [rpmH]. 1 44 16.762 T 11-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_14665 ebecaa8c625441be4f785a355c6cfd47 44 ProDom PD003101 RIBOSOMAL L34 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID L34 MITOCHONDRIAL PEPTIDE SEQUENCING 1 26 1.0E-7 T 11-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_14665 ebecaa8c625441be4f785a355c6cfd47 44 Pfam PF00468 Ribosomal protein L34 1 44 1.2E-24 T 11-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_14665 ebecaa8c625441be4f785a355c6cfd47 44 TIGRFAM TIGR01030 rpmH_bact: ribosomal protein bL34 1 44 1.6E-22 T 11-10-2018 IPR000271 Ribosomal protein L34 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_11960 42746ba5b51c1d33f983b52167680429 216 TIGRFAM TIGR00091 TIGR00091: tRNA (guanine-N(7)-)-methyltransferase 26 210 3.6E-61 T 11-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 AFK25_11960 42746ba5b51c1d33f983b52167680429 216 Gene3D G3DSA:3.40.50.150 1 211 4.7E-75 T 11-10-2018 AFK25_11960 42746ba5b51c1d33f983b52167680429 216 Pfam PF02390 Putative methyltransferase 38 207 3.4E-50 T 11-10-2018 AFK25_11960 42746ba5b51c1d33f983b52167680429 216 SUPERFAMILY SSF53335 23 209 3.81E-31 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_11960 42746ba5b51c1d33f983b52167680429 216 Hamap MF_01057 tRNA (guanine-N(7)-)-methyltransferase [trmB]. 1 212 30.341 T 11-10-2018 IPR003358 tRNA (guanine-N-7) methyltransferase, Trmb type GO:0006400|GO:0008176 Reactome: R-HSA-6782315 AFK25_06430 77cffb6290776a0f5e27461f73b52a21 233 Pfam PF04405 Domain of Unknown function (DUF542) 8 61 3.8E-21 T 11-10-2018 IPR019903 Repair of iron centres family AFK25_06430 77cffb6290776a0f5e27461f73b52a21 233 TIGRFAM TIGR03652 FeS_repair_RIC: iron-sulfur cluster repair di-iron protein 11 229 2.9E-84 T 11-10-2018 IPR019903 Repair of iron centres family AFK25_06430 77cffb6290776a0f5e27461f73b52a21 233 Gene3D G3DSA:1.10.3910.10 1 67 2.5E-6 T 11-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily AFK25_06430 77cffb6290776a0f5e27461f73b52a21 233 Gene3D G3DSA:1.20.120.520 70 231 8.7E-21 T 11-10-2018 AFK25_06430 77cffb6290776a0f5e27461f73b52a21 233 Pfam PF01814 Hemerythrin HHE cation binding domain 82 229 3.9E-23 T 11-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 AFK25_06430 77cffb6290776a0f5e27461f73b52a21 233 SUPERFAMILY SSF140683 1 64 8.63E-5 T 11-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily AFK25_05500 ec83c2e2bb2b6d2657983c374ef71b56 194 Gene3D G3DSA:3.10.129.10 68 186 5.3E-41 T 11-10-2018 AFK25_05500 ec83c2e2bb2b6d2657983c374ef71b56 194 SUPERFAMILY SSF46785 5 51 5.17E-5 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_05500 ec83c2e2bb2b6d2657983c374ef71b56 194 SUPERFAMILY SSF54637 74 182 5.68E-26 T 11-10-2018 IPR029069 HotDog domain superfamily AFK25_05500 ec83c2e2bb2b6d2657983c374ef71b56 194 Gene3D G3DSA:1.10.10.10 1 60 6.5E-28 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_05500 ec83c2e2bb2b6d2657983c374ef71b56 194 PIRSF PIRSF037733 1 190 1.6E-87 T 11-10-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 AFK25_05500 ec83c2e2bb2b6d2657983c374ef71b56 194 Hamap MF_01814 Transcription factor FapR [fapR]. 1 187 40.16 T 11-10-2018 IPR017275 Transcription factor FapR GO:0003700|GO:0045717|GO:0045892 AFK25_05500 ec83c2e2bb2b6d2657983c374ef71b56 194 Pfam PF03061 Thioesterase superfamily 110 156 3.4E-5 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFK25_12985 6503a5eabaa25a88e826829395ca1ccb 252 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 252 49.676 T 11-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 AFK25_12985 6503a5eabaa25a88e826829395ca1ccb 252 Pfam PF00977 Histidine biosynthesis protein 5 235 1.2E-89 T 11-10-2018 IPR006062 Histidine biosynthesis GO:0000105 AFK25_12985 6503a5eabaa25a88e826829395ca1ccb 252 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 252 1.5E-121 T 11-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 AFK25_12985 6503a5eabaa25a88e826829395ca1ccb 252 Gene3D G3DSA:3.20.20.70 1 252 1.8E-109 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_12985 6503a5eabaa25a88e826829395ca1ccb 252 SUPERFAMILY SSF51366 1 252 1.18E-84 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFK25_06945 2d95d07edb3fb15508575e50c1c07ede 298 SUPERFAMILY SSF103481 39 138 1.83E-13 T 11-10-2018 AFK25_06945 2d95d07edb3fb15508575e50c1c07ede 298 SUPERFAMILY SSF103481 201 286 2.22E-14 T 11-10-2018 AFK25_06945 2d95d07edb3fb15508575e50c1c07ede 298 Pfam PF00892 EamA-like transporter family 144 281 1.6E-17 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFK25_06945 2d95d07edb3fb15508575e50c1c07ede 298 Pfam PF00892 EamA-like transporter family 5 135 3.7E-21 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFK25_08115 ba1d8b16a308d74a42a28157e005d966 640 Pfam PF14804 Jag N-terminus 6 54 2.2E-16 T 11-10-2018 IPR032782 Jag, N-terminal AFK25_08115 ba1d8b16a308d74a42a28157e005d966 640 Pfam PF03961 Flagellar Assembly Protein A 131 402 3.2E-67 T 11-10-2018 IPR005646 Flagellar assembly protein A AFK25_08115 ba1d8b16a308d74a42a28157e005d966 640 SMART SM01245 5 56 7.4E-19 T 11-10-2018 IPR032782 Jag, N-terminal AFK25_08115 ba1d8b16a308d74a42a28157e005d966 640 Gene3D G3DSA:3.30.30.80 1 56 1.0E-15 T 11-10-2018 IPR038247 Jag, N-terminal domain superfamily AFK25_10925 5e3105fcfb01fef08177b3a20bee2d1c 111 SUPERFAMILY SSF118010 1 109 2.35E-33 T 11-10-2018 IPR036764 Cysteine protease Prp superfamily AFK25_10925 5e3105fcfb01fef08177b3a20bee2d1c 111 Pfam PF04327 Cysteine protease Prp 1 105 1.5E-26 T 11-10-2018 IPR007422 Cysteine protease Prp AFK25_10925 5e3105fcfb01fef08177b3a20bee2d1c 111 Gene3D G3DSA:3.30.70.1490 1 110 2.2E-34 T 11-10-2018 IPR036764 Cysteine protease Prp superfamily AFK25_09640 6114594780c69798b822082b80b94752 68 Gene3D G3DSA:3.40.5.90 2 65 7.6E-15 T 11-10-2018 AFK25_09640 6114594780c69798b822082b80b94752 68 Pfam PF09360 Iron-binding zinc finger CDGSH type 11 55 3.7E-18 T 11-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 AFK25_09640 6114594780c69798b822082b80b94752 68 SMART SM00704 20 60 8.5E-4 T 11-10-2018 IPR018967 Iron sulphur-containing domain, CDGSH-type GO:0043231|GO:0051537 AFK25_13000 b6a5798b709e6c8e7222fa1c0eaf6b56 195 SUPERFAMILY SSF54211 2 87 3.04E-32 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFK25_13000 b6a5798b709e6c8e7222fa1c0eaf6b56 195 Gene3D G3DSA:3.30.230.40 1 90 5.9E-36 T 11-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 AFK25_13000 b6a5798b709e6c8e7222fa1c0eaf6b56 195 ProSitePatterns PS00954 Imidazoleglycerol-phosphate dehydratase signature 1. 62 75 - T 11-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AFK25_13000 b6a5798b709e6c8e7222fa1c0eaf6b56 195 SUPERFAMILY SSF54211 88 179 7.74E-34 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFK25_13000 b6a5798b709e6c8e7222fa1c0eaf6b56 195 Gene3D G3DSA:3.30.230.40 91 195 6.1E-39 T 11-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 AFK25_13000 b6a5798b709e6c8e7222fa1c0eaf6b56 195 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 157 169 - T 11-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AFK25_13000 b6a5798b709e6c8e7222fa1c0eaf6b56 195 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 32 175 1.0E-62 T 11-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AFK25_13000 b6a5798b709e6c8e7222fa1c0eaf6b56 195 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 3 195 41.852 T 11-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AFK25_09745 72ea6ce977fbc8b5809eccdbdde92692 438 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 28 57 - T 11-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AFK25_09745 72ea6ce977fbc8b5809eccdbdde92692 438 Pfam PF02817 e3 binding domain 119 152 1.7E-13 T 11-10-2018 IPR004167 Peripheral subunit-binding domain GO:0016746 Reactome: R-HSA-389661 AFK25_09745 72ea6ce977fbc8b5809eccdbdde92692 438 SUPERFAMILY SSF51230 2 95 2.09E-27 T 11-10-2018 IPR011053 Single hybrid motif AFK25_09745 72ea6ce977fbc8b5809eccdbdde92692 438 Pfam PF00198 2-oxoacid dehydrogenases acyltransferase (catalytic domain) 209 431 3.1E-84 T 11-10-2018 IPR001078 2-oxoacid dehydrogenase acyltransferase, catalytic domain GO:0016746 Reactome: R-HSA-389661 AFK25_09745 72ea6ce977fbc8b5809eccdbdde92692 438 Gene3D G3DSA:4.10.320.10 110 162 1.4E-16 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 AFK25_09745 72ea6ce977fbc8b5809eccdbdde92692 438 Gene3D G3DSA:2.40.50.100 1 103 6.0E-29 T 11-10-2018 AFK25_09745 72ea6ce977fbc8b5809eccdbdde92692 438 Gene3D G3DSA:3.30.559.10 191 438 2.8E-101 T 11-10-2018 IPR023213 Chloramphenicol acetyltransferase-like domain superfamily Reactome: R-HSA-389661 AFK25_09745 72ea6ce977fbc8b5809eccdbdde92692 438 SUPERFAMILY SSF47005 112 156 5.36E-12 T 11-10-2018 IPR036625 E3-binding domain superfamily GO:0016746 Reactome: R-HSA-389661 AFK25_09745 72ea6ce977fbc8b5809eccdbdde92692 438 Pfam PF00364 Biotin-requiring enzyme 5 77 2.2E-22 T 11-10-2018 IPR000089 Biotin/lipoyl attachment AFK25_09745 72ea6ce977fbc8b5809eccdbdde92692 438 SUPERFAMILY SSF52777 210 430 8.45E-86 T 11-10-2018 AFK25_03245 ad6038551bc56680651d51390651b7e8 274 Pfam PF01903 CbiX 9 114 3.7E-24 T 11-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 AFK25_03245 ad6038551bc56680651d51390651b7e8 274 Pfam PF01903 CbiX 135 238 5.6E-25 T 11-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 AFK25_03245 ad6038551bc56680651d51390651b7e8 274 Gene3D G3DSA:3.40.50.1400 124 247 7.5E-24 T 11-10-2018 AFK25_03245 ad6038551bc56680651d51390651b7e8 274 Gene3D G3DSA:3.40.50.1400 1 122 4.0E-28 T 11-10-2018 AFK25_03245 ad6038551bc56680651d51390651b7e8 274 SUPERFAMILY SSF53800 1 246 1.85E-54 T 11-10-2018 AFK25_06275 d5ce62627ea7cabaa46331d6b4fa7fe5 83 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 10 49 3.8E-8 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFK25_06275 d5ce62627ea7cabaa46331d6b4fa7fe5 83 Gene3D G3DSA:2.10.260.10 3 81 2.6E-11 T 11-10-2018 AFK25_06275 d5ce62627ea7cabaa46331d6b4fa7fe5 83 SUPERFAMILY SSF89447 7 52 1.55E-12 T 11-10-2018 IPR037914 SpoVT-AbrB domain superfamily AFK25_06275 d5ce62627ea7cabaa46331d6b4fa7fe5 83 SMART SM00966 9 54 9.1E-8 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFK25_06595 da5d25f046f8e607f4cc61dcd4ddb129 315 ProSitePatterns PS01053 Arginase family signature. 238 259 - T 11-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 AFK25_06595 da5d25f046f8e607f4cc61dcd4ddb129 315 TIGRFAM TIGR01227 hutG: formimidoylglutamase 7 309 7.5E-87 T 11-10-2018 IPR005923 Formiminoglutamase GO:0019556|GO:0050415 KEGG: 00340+3.5.3.8 AFK25_06595 da5d25f046f8e607f4cc61dcd4ddb129 315 SUPERFAMILY SSF52768 35 309 2.88E-77 T 11-10-2018 IPR023696 Ureohydrolase domain superfamily AFK25_06595 da5d25f046f8e607f4cc61dcd4ddb129 315 Gene3D G3DSA:3.40.800.10 22 314 3.7E-94 T 11-10-2018 AFK25_06595 da5d25f046f8e607f4cc61dcd4ddb129 315 PRINTS PR00116 Arginase signature 122 137 6.0E-7 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 AFK25_06595 da5d25f046f8e607f4cc61dcd4ddb129 315 PRINTS PR00116 Arginase signature 235 264 6.0E-7 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 AFK25_06595 da5d25f046f8e607f4cc61dcd4ddb129 315 Pfam PF00491 Arginase family 35 307 5.2E-72 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 AFK25_06595 da5d25f046f8e607f4cc61dcd4ddb129 315 PIRSF PIRSF036979 11 314 1.6E-62 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 AFK25_09515 528332c5615090dfda7c22ca8a7d4ed9 162 Pfam PF01967 MoaC family 15 152 5.5E-53 T 11-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFK25_09515 528332c5615090dfda7c22ca8a7d4ed9 162 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 4 154 6.1E-65 T 11-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFK25_09515 528332c5615090dfda7c22ca8a7d4ed9 162 Gene3D G3DSA:3.30.70.640 1 162 1.5E-68 T 11-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFK25_09515 528332c5615090dfda7c22ca8a7d4ed9 162 SUPERFAMILY SSF55040 11 157 9.55E-58 T 11-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFK25_09515 528332c5615090dfda7c22ca8a7d4ed9 162 Hamap MF_01224_B Cyclic pyranopterin monophosphate synthase [moaC]. 2 160 35.969 T 11-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AFK25_10125 4cf2648bc5bedd031c2764be59ea7d5c 796 Gene3D G3DSA:3.40.120.10 381 526 2.9E-12 T 11-10-2018 AFK25_10125 4cf2648bc5bedd031c2764be59ea7d5c 796 Gene3D G3DSA:3.40.120.10 581 698 9.8E-7 T 11-10-2018 AFK25_10125 4cf2648bc5bedd031c2764be59ea7d5c 796 SUPERFAMILY SSF53448 1 260 5.63E-75 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_10125 4cf2648bc5bedd031c2764be59ea7d5c 796 SUPERFAMILY SSF55957 715 793 1.08E-11 T 11-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_10125 4cf2648bc5bedd031c2764be59ea7d5c 796 SUPERFAMILY SSF53738 376 509 3.77E-11 T 11-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_10125 4cf2648bc5bedd031c2764be59ea7d5c 796 SUPERFAMILY SSF51161 246 368 1.49E-23 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily AFK25_10125 4cf2648bc5bedd031c2764be59ea7d5c 796 Gene3D G3DSA:3.30.310.50 715 796 3.3E-10 T 11-10-2018 AFK25_10125 4cf2648bc5bedd031c2764be59ea7d5c 796 Gene3D G3DSA:2.160.10.10 238 380 2.1E-19 T 11-10-2018 AFK25_10125 4cf2648bc5bedd031c2764be59ea7d5c 796 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 266 296 1.5E-4 T 11-10-2018 IPR001451 Hexapeptide repeat AFK25_10125 4cf2648bc5bedd031c2764be59ea7d5c 796 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 382 507 1.6E-9 T 11-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AFK25_10125 4cf2648bc5bedd031c2764be59ea7d5c 796 Gene3D G3DSA:3.90.550.10 1 237 1.0E-72 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_10125 4cf2648bc5bedd031c2764be59ea7d5c 796 Pfam PF00483 Nucleotidyl transferase 2 232 2.1E-47 T 11-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFK25_10125 4cf2648bc5bedd031c2764be59ea7d5c 796 Gene3D G3DSA:3.40.120.10 612 700 9.8E-7 T 11-10-2018 AFK25_08725 6d576e906d5c9b8ecbc09ff1f40f5a1f 430 SUPERFAMILY SSF55681 110 424 6.84E-100 T 11-10-2018 AFK25_08725 6d576e906d5c9b8ecbc09ff1f40f5a1f 430 TIGRFAM TIGR00457 asnS: asparagine--tRNA ligase 1 429 1.9E-167 T 11-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 AFK25_08725 6d576e906d5c9b8ecbc09ff1f40f5a1f 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 180 192 1.3E-15 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_08725 6d576e906d5c9b8ecbc09ff1f40f5a1f 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 385 399 1.3E-15 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_08725 6d576e906d5c9b8ecbc09ff1f40f5a1f 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 196 209 1.3E-15 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_08725 6d576e906d5c9b8ecbc09ff1f40f5a1f 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 345 361 1.3E-15 T 11-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_08725 6d576e906d5c9b8ecbc09ff1f40f5a1f 430 SUPERFAMILY SSF50249 9 102 7.43E-25 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_08725 6d576e906d5c9b8ecbc09ff1f40f5a1f 430 Hamap MF_00534 Asparagine--tRNA ligase [asnS]. 1 430 42.287 T 11-10-2018 IPR004522 Asparagine-tRNA ligase GO:0000166|GO:0004816|GO:0005524|GO:0005737|GO:0006421 KEGG: 00970+6.1.1.22 AFK25_08725 6d576e906d5c9b8ecbc09ff1f40f5a1f 430 Pfam PF00152 tRNA synthetases class II (D, K and N) 111 424 9.8E-87 T 11-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_08725 6d576e906d5c9b8ecbc09ff1f40f5a1f 430 Gene3D G3DSA:3.30.930.10 101 430 1.5E-120 T 11-10-2018 AFK25_08725 6d576e906d5c9b8ecbc09ff1f40f5a1f 430 Pfam PF01336 OB-fold nucleic acid binding domain 16 95 1.3E-16 T 11-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AFK25_08725 6d576e906d5c9b8ecbc09ff1f40f5a1f 430 Gene3D G3DSA:2.40.50.140 2 100 1.3E-24 T 11-10-2018 AFK25_12000 45cc9d9a8fbe17d1806b1a4509fa1413 176 SUPERFAMILY SSF55144 1 175 7.85E-39 T 11-10-2018 IPR009097 Cyclic phosphodiesterase AFK25_12000 45cc9d9a8fbe17d1806b1a4509fa1413 176 Gene3D G3DSA:3.90.1140.10 1 175 5.8E-38 T 11-10-2018 AFK25_12000 45cc9d9a8fbe17d1806b1a4509fa1413 176 Pfam PF13563 2'-5' RNA ligase superfamily 33 126 6.9E-14 T 11-10-2018 AFK25_12000 45cc9d9a8fbe17d1806b1a4509fa1413 176 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 175 7.3E-40 T 11-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 AFK25_12000 45cc9d9a8fbe17d1806b1a4509fa1413 176 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 175 20.978 T 11-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 AFK25_04670 8e7bc78f0e9e7fb4190a6be0822a0f5c 255 Gene3D G3DSA:3.40.50.720 1 254 1.2E-74 T 11-10-2018 AFK25_04670 8e7bc78f0e9e7fb4190a6be0822a0f5c 255 SUPERFAMILY SSF51735 2 252 6.53E-78 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_04670 8e7bc78f0e9e7fb4190a6be0822a0f5c 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 130 138 5.6E-6 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04670 8e7bc78f0e9e7fb4190a6be0822a0f5c 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 5.6E-6 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04670 8e7bc78f0e9e7fb4190a6be0822a0f5c 255 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 150 169 5.6E-6 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04670 8e7bc78f0e9e7fb4190a6be0822a0f5c 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 124 140 5.0E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04670 8e7bc78f0e9e7fb4190a6be0822a0f5c 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 150 169 5.0E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04670 8e7bc78f0e9e7fb4190a6be0822a0f5c 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 171 188 5.0E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04670 8e7bc78f0e9e7fb4190a6be0822a0f5c 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 215 235 5.0E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04670 8e7bc78f0e9e7fb4190a6be0822a0f5c 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 5.0E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04670 8e7bc78f0e9e7fb4190a6be0822a0f5c 255 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 5.0E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04670 8e7bc78f0e9e7fb4190a6be0822a0f5c 255 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 8 251 7.1E-58 T 11-10-2018 AFK25_10035 bb0ef5dc6965ce6fde06a56aa79c0644 358 SMART SM00382 138 260 1.1E-4 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_10035 bb0ef5dc6965ce6fde06a56aa79c0644 358 SUPERFAMILY SSF52540 4 330 1.89E-71 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_10035 bb0ef5dc6965ce6fde06a56aa79c0644 358 Gene3D G3DSA:3.30.450.90 2 110 1.7E-30 T 11-10-2018 AFK25_10035 bb0ef5dc6965ce6fde06a56aa79c0644 358 Pfam PF00437 Type II/IV secretion system protein 18 277 1.4E-73 T 11-10-2018 IPR001482 Type II/IV secretion system protein AFK25_10035 bb0ef5dc6965ce6fde06a56aa79c0644 358 Gene3D G3DSA:3.40.50.300 113 349 1.5E-68 T 11-10-2018 AFK25_10035 bb0ef5dc6965ce6fde06a56aa79c0644 358 ProSitePatterns PS00662 Bacterial type II secretion system protein E signature. 206 220 - T 11-10-2018 IPR001482 Type II/IV secretion system protein AFK25_07045 01d46a56a39ccc548e549fdaad1f48df 173 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 1 149 1.6E-34 T 11-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase AFK25_07045 01d46a56a39ccc548e549fdaad1f48df 173 PIRSF PIRSF030780 1 33 270.0 T 11-10-2018 IPR016956 Inner membrane protein YdjM AFK25_07045 01d46a56a39ccc548e549fdaad1f48df 173 PIRSF PIRSF030780 25 167 8.4E-22 T 11-10-2018 IPR016956 Inner membrane protein YdjM AFK25_11050 b34450cbb36c31bfc7fe5ba0068f492e 189 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 8 30 2.6E-6 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_11050 b34450cbb36c31bfc7fe5ba0068f492e 189 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 8 28 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_11050 b34450cbb36c31bfc7fe5ba0068f492e 189 SUPERFAMILY SSF54523 11 83 9.42E-6 T 11-10-2018 AFK25_11050 b34450cbb36c31bfc7fe5ba0068f492e 189 Pfam PF07963 Prokaryotic N-terminal methylation motif 6 30 1.6E-7 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_05260 12fa2d28b7b5f9a2be884146f5f14339 372 ProSitePatterns PS01134 FtsZ protein signature 1. 44 78 - T 11-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 AFK25_05260 12fa2d28b7b5f9a2be884146f5f14339 372 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 7 327 8.5E-141 T 11-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 AFK25_05260 12fa2d28b7b5f9a2be884146f5f14339 372 Pfam PF12327 FtsZ family, C-terminal domain 222 315 1.5E-33 T 11-10-2018 IPR024757 Cell division protein FtsZ, C-terminal AFK25_05260 12fa2d28b7b5f9a2be884146f5f14339 372 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 9 346 39.92 T 11-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 AFK25_05260 12fa2d28b7b5f9a2be884146f5f14339 372 SUPERFAMILY SSF52490 12 208 3.66E-74 T 11-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AFK25_05260 12fa2d28b7b5f9a2be884146f5f14339 372 PRINTS PR00423 Cell division protein FtsZ signature 189 211 9.3E-53 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFK25_05260 12fa2d28b7b5f9a2be884146f5f14339 372 PRINTS PR00423 Cell division protein FtsZ signature 98 118 9.3E-53 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFK25_05260 12fa2d28b7b5f9a2be884146f5f14339 372 PRINTS PR00423 Cell division protein FtsZ signature 212 233 9.3E-53 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFK25_05260 12fa2d28b7b5f9a2be884146f5f14339 372 PRINTS PR00423 Cell division protein FtsZ signature 126 147 9.3E-53 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFK25_05260 12fa2d28b7b5f9a2be884146f5f14339 372 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 14 173 1.1E-45 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFK25_05260 12fa2d28b7b5f9a2be884146f5f14339 372 SMART SM00864 13 205 6.3E-120 T 11-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AFK25_05260 12fa2d28b7b5f9a2be884146f5f14339 372 ProSitePatterns PS01135 FtsZ protein signature 2. 97 118 - T 11-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 AFK25_05260 12fa2d28b7b5f9a2be884146f5f14339 372 Gene3D G3DSA:3.30.1330.20 221 333 4.9E-43 T 11-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 AFK25_05260 12fa2d28b7b5f9a2be884146f5f14339 372 SUPERFAMILY SSF55307 204 318 5.72E-45 T 11-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 AFK25_05260 12fa2d28b7b5f9a2be884146f5f14339 372 Gene3D G3DSA:3.40.50.1440 4 220 2.6E-85 T 11-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AFK25_05260 12fa2d28b7b5f9a2be884146f5f14339 372 SMART SM00865 207 324 9.2E-56 T 11-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 AFK25_07160 286cb959141992afa42310c725336960 264 Hamap MF_00008 Thymidylate synthase [thyA]. 1 264 39.273 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFK25_07160 286cb959141992afa42310c725336960 264 ProSitePatterns PS00091 Thymidylate synthase active site. 126 154 - T 11-10-2018 IPR020940 Thymidylate synthase, active site GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFK25_07160 286cb959141992afa42310c725336960 264 Pfam PF00303 Thymidylate synthase 2 264 6.1E-126 T 11-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFK25_07160 286cb959141992afa42310c725336960 264 PRINTS PR00108 Thymidylate synthase family signature 42 63 7.1E-45 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFK25_07160 286cb959141992afa42310c725336960 264 PRINTS PR00108 Thymidylate synthase family signature 115 134 7.1E-45 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFK25_07160 286cb959141992afa42310c725336960 264 PRINTS PR00108 Thymidylate synthase family signature 159 185 7.1E-45 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFK25_07160 286cb959141992afa42310c725336960 264 PRINTS PR00108 Thymidylate synthase family signature 141 156 7.1E-45 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFK25_07160 286cb959141992afa42310c725336960 264 PRINTS PR00108 Thymidylate synthase family signature 197 214 7.1E-45 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFK25_07160 286cb959141992afa42310c725336960 264 Gene3D G3DSA:3.30.572.10 1 264 7.1E-132 T 11-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFK25_07160 286cb959141992afa42310c725336960 264 SUPERFAMILY SSF55831 1 264 6.02E-128 T 11-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFK25_07160 286cb959141992afa42310c725336960 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 84 264 2.8E-86 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFK25_07160 286cb959141992afa42310c725336960 264 TIGRFAM TIGR03284 thym_sym: thymidylate synthase 2 85 5.4E-41 T 11-10-2018 IPR000398 Thymidylate synthase GO:0004799|GO:0006231 KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AFK25_12075 4be843ffc54baf46115de8a78c133c32 272 Gene3D G3DSA:3.40.50.1820 1 259 5.6E-51 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold AFK25_12075 4be843ffc54baf46115de8a78c133c32 272 Pfam PF12146 Serine aminopeptidase, S33 8 242 9.6E-58 T 11-10-2018 IPR022742 Serine aminopeptidase, S33 AFK25_12075 4be843ffc54baf46115de8a78c133c32 272 SUPERFAMILY SSF53474 3 255 3.57E-35 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold AFK25_12075 4be843ffc54baf46115de8a78c133c32 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 198 212 1.9E-6 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFK25_12075 4be843ffc54baf46115de8a78c133c32 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 37 52 1.9E-6 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFK25_12075 4be843ffc54baf46115de8a78c133c32 272 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 98 1.9E-6 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFK25_10230 8b64c05249c1d43f513df747fa499c70 297 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 235 289 4.5E-23 T 11-10-2018 IPR019264 Domain of unknown function DUF2179 AFK25_10230 8b64c05249c1d43f513df747fa499c70 297 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 23 229 8.8E-65 T 11-10-2018 IPR003740 Uncharacterised membrane protein YitT AFK25_10230 8b64c05249c1d43f513df747fa499c70 297 PIRSF PIRSF006483 4 296 6.5E-91 T 11-10-2018 IPR003740 Uncharacterised membrane protein YitT AFK25_10230 8b64c05249c1d43f513df747fa499c70 297 Gene3D G3DSA:3.30.70.120 207 282 3.0E-26 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AFK25_03765 9f071604fc06ba7b0ea6e72fc8f1bf69 379 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 187 201 - T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFK25_03765 9f071604fc06ba7b0ea6e72fc8f1bf69 379 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 376 9.0E-149 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFK25_03765 9f071604fc06ba7b0ea6e72fc8f1bf69 379 SUPERFAMILY SSF53383 12 377 1.14E-114 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_03765 9f071604fc06ba7b0ea6e72fc8f1bf69 379 Gene3D G3DSA:3.90.1150.10 245 379 1.0E-47 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_03765 9f071604fc06ba7b0ea6e72fc8f1bf69 379 Gene3D G3DSA:3.40.640.10 1 244 1.2E-91 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_03765 9f071604fc06ba7b0ea6e72fc8f1bf69 379 PIRSF PIRSF001434 1 379 6.8E-147 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFK25_05220 a63ce230740fa496a449e83b11d14889 354 ProSitePatterns PS00428 Cell cycle proteins ftsW / rodA / spoVE signature. 310 334 - T 11-10-2018 IPR018365 Cell cycle, FtsW / RodA / SpoVE, conserved site GO:0016021 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_05220 a63ce230740fa496a449e83b11d14889 354 TIGRFAM TIGR02615 spoVE: stage V sporulation protein E 1 350 1.4E-179 T 11-10-2018 IPR013438 Sporulation stage V, protein E AFK25_05220 a63ce230740fa496a449e83b11d14889 354 TIGRFAM TIGR02614 ftsW: cell division protein FtsW 2 351 6.3E-133 T 11-10-2018 IPR013437 Probable peptidoglycan glycosyltransferase FtsW GO:0009252|GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_05220 a63ce230740fa496a449e83b11d14889 354 Pfam PF01098 Cell cycle protein 2 353 1.8E-130 T 11-10-2018 IPR001182 Probable peptidoglycan glycosyltransferase FtsW/RodA GO:0016021|GO:0051301 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_10200 f3243327b6b6d020ebd030f36f938472 363 SUPERFAMILY SSF56014 264 351 1.44E-14 T 11-10-2018 AFK25_10200 f3243327b6b6d020ebd030f36f938472 363 TIGRFAM TIGR00612 ispG_gcpE: 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 7 350 5.5E-135 T 11-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 AFK25_10200 f3243327b6b6d020ebd030f36f938472 363 SUPERFAMILY SSF51717 15 212 8.63E-18 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_10200 f3243327b6b6d020ebd030f36f938472 363 Pfam PF04551 GcpE protein 10 351 2.7E-142 T 11-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 AFK25_10200 f3243327b6b6d020ebd030f36f938472 363 Gene3D G3DSA:3.20.20.20 1 259 2.0E-112 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_10200 f3243327b6b6d020ebd030f36f938472 363 PIRSF PIRSF004640 1 361 1.6E-157 T 11-10-2018 IPR016425 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial GO:0005506|GO:0008299|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 AFK25_10200 f3243327b6b6d020ebd030f36f938472 363 Gene3D G3DSA:3.30.413.10 261 360 9.0E-36 T 11-10-2018 AFK25_10200 f3243327b6b6d020ebd030f36f938472 363 Hamap MF_00159 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (ferredoxin) [ispG]. 5 355 35.541 T 11-10-2018 IPR004588 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase, bacterial-type GO:0016114|GO:0046429|GO:0055114 KEGG: 00900+1.17.7.3 AFK25_01840 35c2e0f67d6cad5911ba9aa3938b912d 205 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 168 183 4.0E-5 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFK25_01840 35c2e0f67d6cad5911ba9aa3938b912d 205 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 152 168 4.0E-5 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFK25_01840 35c2e0f67d6cad5911ba9aa3938b912d 205 SMART SM00419 146 194 3.4E-9 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFK25_01840 35c2e0f67d6cad5911ba9aa3938b912d 205 Gene3D G3DSA:1.10.10.10 128 200 1.5E-20 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_01840 35c2e0f67d6cad5911ba9aa3938b912d 205 Pfam PF13545 Crp-like helix-turn-helix domain 135 200 5.8E-15 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFK25_01840 35c2e0f67d6cad5911ba9aa3938b912d 205 Gene3D G3DSA:2.60.120.10 3 127 9.9E-41 T 11-10-2018 IPR014710 RmlC-like jelly roll fold AFK25_01840 35c2e0f67d6cad5911ba9aa3938b912d 205 SMART SM00100 1 114 6.8E-4 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain AFK25_01840 35c2e0f67d6cad5911ba9aa3938b912d 205 SUPERFAMILY SSF51206 12 129 5.24E-28 T 11-10-2018 IPR018490 Cyclic nucleotide-binding-like AFK25_01840 35c2e0f67d6cad5911ba9aa3938b912d 205 Pfam PF00027 Cyclic nucleotide-binding domain 14 101 8.2E-16 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain AFK25_01840 35c2e0f67d6cad5911ba9aa3938b912d 205 SUPERFAMILY SSF46785 132 200 1.77E-15 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_04270 a30993e3b8bca28165b742bfb1e607c5 367 SUPERFAMILY SSF103190 9 91 1.14E-5 T 11-10-2018 IPR029151 Periplasmic sensor-like domain superfamily AFK25_04270 a30993e3b8bca28165b742bfb1e607c5 367 Pfam PF13556 PucR C-terminal helix-turn-helix domain 302 359 3.8E-20 T 11-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain AFK25_04270 a30993e3b8bca28165b742bfb1e607c5 367 Gene3D G3DSA:1.10.10.2840 241 363 2.5E-22 T 11-10-2018 AFK25_04270 a30993e3b8bca28165b742bfb1e607c5 367 Pfam PF05651 Putative sugar diacid recognition 2 135 1.6E-49 T 11-10-2018 IPR008599 Putative sugar diacid recognition AFK25_04270 a30993e3b8bca28165b742bfb1e607c5 367 SUPERFAMILY SSF55073 180 262 5.96E-5 T 11-10-2018 IPR029787 Nucleotide cyclase AFK25_08875 31076cdbb972bf1e8bcbca78490f1799 371 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 4 357 5.3E-115 T 11-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AFK25_08875 31076cdbb972bf1e8bcbca78490f1799 371 Gene3D G3DSA:3.90.1150.10 20 351 2.3E-118 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_08875 31076cdbb972bf1e8bcbca78490f1799 371 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 359 63.36 T 11-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AFK25_08875 31076cdbb972bf1e8bcbca78490f1799 371 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 219 228 - T 11-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 AFK25_08875 31076cdbb972bf1e8bcbca78490f1799 371 Pfam PF00155 Aminotransferase class I and II 30 355 7.2E-61 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFK25_08875 31076cdbb972bf1e8bcbca78490f1799 371 Gene3D G3DSA:3.40.640.10 43 267 2.3E-118 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_08875 31076cdbb972bf1e8bcbca78490f1799 371 SUPERFAMILY SSF53383 12 358 1.88E-84 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_07945 ce080ce84b40f323899f54998a1c4e0a 373 TIGRFAM TIGR01928 menC_lowGC/arch: o-succinylbenzoate synthase 12 334 8.4E-119 T 11-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 AFK25_07945 ce080ce84b40f323899f54998a1c4e0a 373 Hamap MF_01933 o-succinylbenzoate synthase [menC]. 3 361 44.654 T 11-10-2018 IPR010197 o-Succinylbenzoate synthase, MenC type 2 GO:0009234|GO:0016829 KEGG: 00130+4.2.1.113|MetaCyc: PWY-5837 AFK25_07945 ce080ce84b40f323899f54998a1c4e0a 373 Gene3D G3DSA:3.20.20.120 120 348 1.9E-133 T 11-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFK25_07945 ce080ce84b40f323899f54998a1c4e0a 373 Pfam PF13378 Enolase C-terminal domain-like 149 356 4.5E-47 T 11-10-2018 IPR029065 Enolase C-terminal domain-like AFK25_07945 ce080ce84b40f323899f54998a1c4e0a 373 SUPERFAMILY SSF54826 5 128 1.28E-33 T 11-10-2018 AFK25_07945 ce080ce84b40f323899f54998a1c4e0a 373 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 7 127 7.3E-13 T 11-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain AFK25_07945 ce080ce84b40f323899f54998a1c4e0a 373 SUPERFAMILY SSF51604 116 365 2.36E-65 T 11-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFK25_07945 ce080ce84b40f323899f54998a1c4e0a 373 SMART SM00922 144 236 4.5E-22 T 11-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal AFK25_07945 ce080ce84b40f323899f54998a1c4e0a 373 Gene3D G3DSA:3.30.390.10 10 360 1.9E-133 T 11-10-2018 IPR029017 Enolase-like, N-terminal AFK25_04840 9f1ec761adac75f38f925cb4df5a2ef2 555 Hamap MF_01491 Ribonuclease J [rnj]. 4 555 47.524 T 11-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 AFK25_04840 9f1ec761adac75f38f925cb4df5a2ef2 555 Gene3D G3DSA:3.60.15.10 12 442 1.6E-191 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_04840 9f1ec761adac75f38f925cb4df5a2ef2 555 Pfam PF00753 Metallo-beta-lactamase superfamily 19 167 2.0E-15 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_04840 9f1ec761adac75f38f925cb4df5a2ef2 555 SMART SM00849 21 215 2.0E-26 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_04840 9f1ec761adac75f38f925cb4df5a2ef2 555 Gene3D G3DSA:3.10.20.580 449 555 2.0E-38 T 11-10-2018 AFK25_04840 9f1ec761adac75f38f925cb4df5a2ef2 555 TIGRFAM TIGR00649 MG423: beta-CASP ribonuclease, RNase J family 10 553 1.6E-226 T 11-10-2018 IPR004613 Ribonuclease J GO:0003723|GO:0046872 AFK25_04840 9f1ec761adac75f38f925cb4df5a2ef2 555 SUPERFAMILY SSF56281 11 422 2.4E-94 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_04840 9f1ec761adac75f38f925cb4df5a2ef2 555 PIRSF PIRSF004803 1 555 7.9E-245 T 11-10-2018 IPR030854 Ribonuclease J, bacteria GO:0004521|GO:0004534|GO:0006396|GO:0008270|GO:0090501 AFK25_04840 9f1ec761adac75f38f925cb4df5a2ef2 555 ProSitePatterns PS01292 Uncharacterized protein family UPF0036 signature. 364 392 - T 11-10-2018 IPR001587 Ribonuclease J, conserved site AFK25_04840 9f1ec761adac75f38f925cb4df5a2ef2 555 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 361 407 3.0E-9 T 11-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain AFK25_04840 9f1ec761adac75f38f925cb4df5a2ef2 555 Gene3D G3DSA:3.40.50.10710 207 357 1.6E-191 T 11-10-2018 AFK25_11850 5606f39d6e01b5b86fb367411cb9ebbc 928 Gene3D G3DSA:1.10.3810.10 94 301 6.8E-70 T 11-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_11850 5606f39d6e01b5b86fb367411cb9ebbc 928 Pfam PF00912 Transglycosylase 88 270 7.4E-58 T 11-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_11850 5606f39d6e01b5b86fb367411cb9ebbc 928 SUPERFAMILY SSF53955 70 292 1.18E-66 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily AFK25_11850 5606f39d6e01b5b86fb367411cb9ebbc 928 Gene3D G3DSA:3.40.710.10 364 696 2.3E-140 T 11-10-2018 AFK25_11850 5606f39d6e01b5b86fb367411cb9ebbc 928 Gene3D G3DSA:2.60.40.10 824 905 4.2E-8 T 11-10-2018 IPR013783 Immunoglobulin-like fold AFK25_11850 5606f39d6e01b5b86fb367411cb9ebbc 928 Gene3D G3DSA:1.10.20.80 306 589 2.3E-140 T 11-10-2018 AFK25_11850 5606f39d6e01b5b86fb367411cb9ebbc 928 Pfam PF00905 Penicillin binding protein transpeptidase domain 407 652 3.6E-29 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFK25_11850 5606f39d6e01b5b86fb367411cb9ebbc 928 SUPERFAMILY SSF56601 256 731 1.58E-109 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFK25_06730 dccb37bab07302b090abd174bfc194e2 345 Hamap MF_00268 Protein RecA [recA]. 4 328 53.788 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFK25_06730 dccb37bab07302b090abd174bfc194e2 345 TIGRFAM TIGR02012 tigrfam_recA: protein RecA 3 323 6.2E-178 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFK25_06730 dccb37bab07302b090abd174bfc194e2 345 Gene3D G3DSA:3.40.50.300 25 266 5.4E-82 T 11-10-2018 AFK25_06730 dccb37bab07302b090abd174bfc194e2 345 SUPERFAMILY SSF54752 267 326 3.92E-23 T 11-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal AFK25_06730 dccb37bab07302b090abd174bfc194e2 345 ProSitePatterns PS00321 recA signature. 212 220 - T 11-10-2018 IPR020584 DNA recombination/repair protein RecA, conserved site GO:0003677|GO:0005524|GO:0006259|GO:0008094 AFK25_06730 dccb37bab07302b090abd174bfc194e2 345 PRINTS PR00142 RecA protein signature 242 271 8.4E-86 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFK25_06730 dccb37bab07302b090abd174bfc194e2 345 PRINTS PR00142 RecA protein signature 92 121 8.4E-86 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFK25_06730 dccb37bab07302b090abd174bfc194e2 345 PRINTS PR00142 RecA protein signature 209 237 8.4E-86 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFK25_06730 dccb37bab07302b090abd174bfc194e2 345 PRINTS PR00142 RecA protein signature 296 313 8.4E-86 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFK25_06730 dccb37bab07302b090abd174bfc194e2 345 PRINTS PR00142 RecA protein signature 164 193 8.4E-86 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFK25_06730 dccb37bab07302b090abd174bfc194e2 345 PRINTS PR00142 RecA protein signature 126 155 8.4E-86 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFK25_06730 dccb37bab07302b090abd174bfc194e2 345 Gene3D G3DSA:3.30.250.10 267 343 8.5E-31 T 11-10-2018 IPR023400 DNA recombination and repair protein RecA, C-terminal AFK25_06730 dccb37bab07302b090abd174bfc194e2 345 SMART SM00382 56 227 6.3E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_06730 dccb37bab07302b090abd174bfc194e2 345 SUPERFAMILY SSF52540 2 266 7.09E-66 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_06730 dccb37bab07302b090abd174bfc194e2 345 Pfam PF00154 recA bacterial DNA recombination protein 7 267 5.3E-148 T 11-10-2018 IPR013765 DNA recombination and repair protein RecA GO:0003697|GO:0005524|GO:0006281 AFK25_13055 3b5d09ed3c9b9a3b7632ea91440c12c0 109 Pfam PF09685 Domain of unknown function (DUF4870) 5 96 1.9E-9 T 11-10-2018 IPR019109 Protein of unknown function DUF4870 AFK25_13055 3b5d09ed3c9b9a3b7632ea91440c12c0 109 ProDom PD070949 MEMBRANE PROTEIN YVLA SPANNING SIMILAR SE2241 LMO0604 LMO2177 LIN2280 INTEGRAL 1 55 6.0E-15 T 11-10-2018 AFK25_10545 5eedf57c6f397f473755cc332142146c 327 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 6 322 1.1E-100 T 11-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 AFK25_10545 5eedf57c6f397f473755cc332142146c 327 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 312 26.356 T 11-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 AFK25_10545 5eedf57c6f397f473755cc332142146c 327 Gene3D G3DSA:1.20.120.920 83 323 1.0E-72 T 11-10-2018 AFK25_10545 5eedf57c6f397f473755cc332142146c 327 Gene3D G3DSA:3.100.10.20 2 81 5.0E-30 T 11-10-2018 AFK25_10545 5eedf57c6f397f473755cc332142146c 327 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 4 327 1.1E-138 T 11-10-2018 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 AFK25_10545 5eedf57c6f397f473755cc332142146c 327 Pfam PF01867 CRISPR associated protein Cas1 6 282 1.1E-93 T 11-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 AFK25_05100 70fd8f028b89590995143effcb8c7d37 149 SUPERFAMILY SSF158622 5 127 3.14E-36 T 11-10-2018 IPR023378 YheA/YmcA-like domain superfamily AFK25_05100 70fd8f028b89590995143effcb8c7d37 149 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 12 116 2.1E-22 T 11-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA AFK25_05100 70fd8f028b89590995143effcb8c7d37 149 Gene3D G3DSA:1.20.1500.10 4 127 5.3E-30 T 11-10-2018 IPR023378 YheA/YmcA-like domain superfamily AFK25_08885 bfd6af6c9af20a35926cc485ee08de1d 398 PIRSF PIRSF001413 2 398 8.8E-162 T 11-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFK25_08885 bfd6af6c9af20a35926cc485ee08de1d 398 Gene3D G3DSA:3.40.50.1100 12 208 1.5E-180 T 11-10-2018 AFK25_08885 bfd6af6c9af20a35926cc485ee08de1d 398 SUPERFAMILY SSF53686 5 392 4.71E-142 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFK25_08885 bfd6af6c9af20a35926cc485ee08de1d 398 Gene3D G3DSA:3.40.50.1100 56 385 1.5E-180 T 11-10-2018 AFK25_08885 bfd6af6c9af20a35926cc485ee08de1d 398 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 83 97 - T 11-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFK25_08885 bfd6af6c9af20a35926cc485ee08de1d 398 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 4 392 51.817 T 11-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFK25_08885 bfd6af6c9af20a35926cc485ee08de1d 398 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 55 378 1.1E-43 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFK25_08885 bfd6af6c9af20a35926cc485ee08de1d 398 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 9 391 1.3E-187 T 11-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFK25_10265 6ba7856600f3d74dda7f3e361c39f5a0 234 PIRSF PIRSF018637 4 234 1.1E-85 T 11-10-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 AFK25_10265 6ba7856600f3d74dda7f3e361c39f5a0 234 Gene3D G3DSA:3.40.50.150 1 163 7.0E-55 T 11-10-2018 AFK25_10265 6ba7856600f3d74dda7f3e361c39f5a0 234 Pfam PF04816 tRNA (adenine(22)-N(1))-methyltransferase 23 229 9.4E-71 T 11-10-2018 IPR006901 tRNA methyltransferase TrmK GO:0016429 AFK25_10265 6ba7856600f3d74dda7f3e361c39f5a0 234 SUPERFAMILY SSF53335 9 102 1.19E-8 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_12895 02c4b3a3121db5e83a23a059bdd86a77 431 Gene3D G3DSA:3.20.20.120 130 431 8.6E-142 T 11-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFK25_12895 02c4b3a3121db5e83a23a059bdd86a77 431 Hamap MF_00318 Enolase [eno]. 2 414 46.543 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFK25_12895 02c4b3a3121db5e83a23a059bdd86a77 431 TIGRFAM TIGR01060 eno: phosphopyruvate hydratase 4 428 8.9E-221 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFK25_12895 02c4b3a3121db5e83a23a059bdd86a77 431 SUPERFAMILY SSF51604 139 429 2.26E-134 T 11-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFK25_12895 02c4b3a3121db5e83a23a059bdd86a77 431 PIRSF PIRSF001400 1 428 1.8E-198 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFK25_12895 02c4b3a3121db5e83a23a059bdd86a77 431 Gene3D G3DSA:3.30.390.10 3 129 2.0E-58 T 11-10-2018 IPR029017 Enolase-like, N-terminal AFK25_12895 02c4b3a3121db5e83a23a059bdd86a77 431 ProSitePatterns PS00164 Enolase signature. 337 350 - T 11-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12895 02c4b3a3121db5e83a23a059bdd86a77 431 SMART SM01193 4 135 6.2E-98 T 11-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFK25_12895 02c4b3a3121db5e83a23a059bdd86a77 431 Pfam PF03952 Enolase, N-terminal domain 4 135 8.5E-62 T 11-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFK25_12895 02c4b3a3121db5e83a23a059bdd86a77 431 Pfam PF00113 Enolase, C-terminal TIM barrel domain 141 426 5.7E-143 T 11-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFK25_12895 02c4b3a3121db5e83a23a059bdd86a77 431 SMART SM01192 140 428 1.2E-234 T 11-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFK25_12895 02c4b3a3121db5e83a23a059bdd86a77 431 PRINTS PR00148 Enolase signature 37 51 1.4E-47 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFK25_12895 02c4b3a3121db5e83a23a059bdd86a77 431 PRINTS PR00148 Enolase signature 314 325 1.4E-47 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFK25_12895 02c4b3a3121db5e83a23a059bdd86a77 431 PRINTS PR00148 Enolase signature 162 175 1.4E-47 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFK25_12895 02c4b3a3121db5e83a23a059bdd86a77 431 PRINTS PR00148 Enolase signature 337 351 1.4E-47 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFK25_12895 02c4b3a3121db5e83a23a059bdd86a77 431 PRINTS PR00148 Enolase signature 108 124 1.4E-47 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFK25_12895 02c4b3a3121db5e83a23a059bdd86a77 431 PRINTS PR00148 Enolase signature 366 383 1.4E-47 T 11-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFK25_12895 02c4b3a3121db5e83a23a059bdd86a77 431 SUPERFAMILY SSF54826 3 139 1.41E-59 T 11-10-2018 AFK25_07190 72c1772e1f1d18b7fd9a05b4e6c43fb3 245 SUPERFAMILY SSF52266 34 239 8.18E-35 T 11-10-2018 AFK25_07190 72c1772e1f1d18b7fd9a05b4e6c43fb3 245 Gene3D G3DSA:3.40.50.1110 17 241 2.1E-32 T 11-10-2018 IPR036514 SGNH hydrolase superfamily AFK25_07190 72c1772e1f1d18b7fd9a05b4e6c43fb3 245 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 40 226 9.4E-24 T 11-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFK25_04275 63396563299ccfea455ff2d5184f4b4e 587 SMART SM00283 311 586 1.9E-66 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_04275 63396563299ccfea455ff2d5184f4b4e 587 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 393 540 7.6E-38 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_04275 63396563299ccfea455ff2d5184f4b4e 587 Gene3D G3DSA:1.20.1480.50 188 288 4.1E-11 T 11-10-2018 AFK25_04275 63396563299ccfea455ff2d5184f4b4e 587 Gene3D G3DSA:1.10.287.950 294 587 2.7E-64 T 11-10-2018 AFK25_04275 63396563299ccfea455ff2d5184f4b4e 587 SMART SM00304 229 282 2.5E-7 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_04275 63396563299ccfea455ff2d5184f4b4e 587 SUPERFAMILY SSF58104 253 585 2.88E-62 T 11-10-2018 AFK25_04275 63396563299ccfea455ff2d5184f4b4e 587 Pfam PF00672 HAMP domain 229 278 3.0E-7 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_04190 ca642c7c28d3675fec482fd390915390 471 Gene3D G3DSA:3.40.50.10380 72 233 2.9E-74 T 11-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 AFK25_04190 ca642c7c28d3675fec482fd390915390 471 SMART SM00919 236 458 3.9E-125 T 11-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AFK25_04190 ca642c7c28d3675fec482fd390915390 471 PRINTS PR00072 Malic enzyme signature 263 279 9.7E-7 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 AFK25_04190 ca642c7c28d3675fec482fd390915390 471 PRINTS PR00072 Malic enzyme signature 153 175 9.7E-7 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 AFK25_04190 ca642c7c28d3675fec482fd390915390 471 PRINTS PR00072 Malic enzyme signature 232 248 9.7E-7 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 AFK25_04190 ca642c7c28d3675fec482fd390915390 471 ProSitePatterns PS00331 Malic enzymes signature. 232 248 - T 11-10-2018 IPR015884 Malic enzyme, conserved site GO:0004471|GO:0055114 AFK25_04190 ca642c7c28d3675fec482fd390915390 471 SUPERFAMILY SSF53223 85 234 1.01E-57 T 11-10-2018 AFK25_04190 ca642c7c28d3675fec482fd390915390 471 SMART SM01274 91 224 4.5E-85 T 11-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFK25_04190 ca642c7c28d3675fec482fd390915390 471 Pfam PF00390 Malic enzyme, N-terminal domain 92 224 2.3E-30 T 11-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AFK25_04190 ca642c7c28d3675fec482fd390915390 471 SUPERFAMILY SSF51735 236 465 6.07E-78 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_04190 ca642c7c28d3675fec482fd390915390 471 Gene3D G3DSA:3.40.50.720 234 465 7.9E-82 T 11-10-2018 AFK25_04190 ca642c7c28d3675fec482fd390915390 471 PIRSF PIRSF000106 7 470 1.4E-98 T 11-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 AFK25_04190 ca642c7c28d3675fec482fd390915390 471 Pfam PF03949 Malic enzyme, NAD binding domain 238 458 1.5E-24 T 11-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AFK25_03890 068c6880e3bd63cd6dbac8ed28d17621 353 Gene3D G3DSA:2.120.10.30 18 350 2.7E-96 T 11-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AFK25_03890 068c6880e3bd63cd6dbac8ed28d17621 353 Pfam PF07995 Glucose / Sorbosone dehydrogenase 46 334 1.5E-60 T 11-10-2018 IPR012938 Glucose/Sorbosone dehydrogenase AFK25_03890 068c6880e3bd63cd6dbac8ed28d17621 353 SUPERFAMILY SSF50952 30 334 2.75E-31 T 11-10-2018 IPR011041 Soluble quinoprotein glucose/sorbosone dehydrogenase GO:0003824 AFK25_09825 ff83e91d484936fcb250ebc1191e1818 290 Pfam PF00348 Polyprenyl synthetase 27 264 1.4E-60 T 11-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 AFK25_09825 ff83e91d484936fcb250ebc1191e1818 290 SUPERFAMILY SSF48576 3 271 1.75E-89 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFK25_09825 ff83e91d484936fcb250ebc1191e1818 290 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 78 94 - T 11-10-2018 IPR033749 Polyprenyl synthetase, conserved site AFK25_09825 ff83e91d484936fcb250ebc1191e1818 290 ProSitePatterns PS00444 Polyprenyl synthases signature 2. 209 221 - T 11-10-2018 IPR033749 Polyprenyl synthetase, conserved site AFK25_09825 ff83e91d484936fcb250ebc1191e1818 290 Gene3D G3DSA:1.10.600.10 1 290 1.2E-110 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFK25_04460 83e2099cd26523a6ed90b54fb58f46b3 695 Pfam PF07724 AAA domain (Cdc48 subfamily) 446 597 3.5E-48 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFK25_04460 83e2099cd26523a6ed90b54fb58f46b3 695 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 525 543 2.3E-36 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_04460 83e2099cd26523a6ed90b54fb58f46b3 695 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 558 572 2.3E-36 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_04460 83e2099cd26523a6ed90b54fb58f46b3 695 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 451 469 2.3E-36 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_04460 83e2099cd26523a6ed90b54fb58f46b3 695 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 496 514 2.3E-36 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_04460 83e2099cd26523a6ed90b54fb58f46b3 695 Gene3D G3DSA:1.10.8.60 266 391 9.9E-40 T 11-10-2018 AFK25_04460 83e2099cd26523a6ed90b54fb58f46b3 695 Gene3D G3DSA:4.10.860.10 327 377 9.9E-40 T 11-10-2018 AFK25_04460 83e2099cd26523a6ed90b54fb58f46b3 695 Gene3D G3DSA:3.40.50.300 400 601 1.2E-80 T 11-10-2018 AFK25_04460 83e2099cd26523a6ed90b54fb58f46b3 695 SMART SM01086 603 690 2.5E-32 T 11-10-2018 IPR019489 Clp ATPase, C-terminal AFK25_04460 83e2099cd26523a6ed90b54fb58f46b3 695 Gene3D G3DSA:1.10.8.60 603 695 3.2E-24 T 11-10-2018 AFK25_04460 83e2099cd26523a6ed90b54fb58f46b3 695 SUPERFAMILY SSF52540 396 677 6.85E-78 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_04460 83e2099cd26523a6ed90b54fb58f46b3 695 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 125 257 3.2E-13 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFK25_04460 83e2099cd26523a6ed90b54fb58f46b3 695 Pfam PF02151 UvrB/uvrC motif 334 369 9.0E-7 T 11-10-2018 IPR001943 UVR domain GO:0005515 AFK25_04460 83e2099cd26523a6ed90b54fb58f46b3 695 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 603 678 3.7E-22 T 11-10-2018 IPR019489 Clp ATPase, C-terminal AFK25_04460 83e2099cd26523a6ed90b54fb58f46b3 695 ProSitePatterns PS00871 Chaperonins clpA/B signature 2. 481 499 - T 11-10-2018 IPR028299 ClpA/B, conserved site 2 AFK25_04460 83e2099cd26523a6ed90b54fb58f46b3 695 ProSitePatterns PS00870 Chaperonins clpA/B signature 1. 215 227 - T 11-10-2018 IPR018368 ClpA/B, conserved site 1 GO:0005524 AFK25_04460 83e2099cd26523a6ed90b54fb58f46b3 695 SUPERFAMILY SSF52540 82 364 3.45E-70 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_04460 83e2099cd26523a6ed90b54fb58f46b3 695 Gene3D G3DSA:3.40.50.300 69 262 4.2E-67 T 11-10-2018 AFK25_04460 83e2099cd26523a6ed90b54fb58f46b3 695 SMART SM00382 447 604 1.1E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_04460 83e2099cd26523a6ed90b54fb58f46b3 695 SMART SM00382 120 264 3.7E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_06005 246fdf84905e9141e6911bf2ace03b64 317 Pfam PF02653 Branched-chain amino acid transport system / permease component 11 295 2.9E-43 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFK25_10045 d362c78ab4bd9eb0eb46684fd2f4ac6c 232 Pfam PF12840 Helix-turn-helix domain 6 63 2.0E-9 T 11-10-2018 AFK25_10045 d362c78ab4bd9eb0eb46684fd2f4ac6c 232 Gene3D G3DSA:1.10.10.10 3 81 1.5E-12 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_10045 d362c78ab4bd9eb0eb46684fd2f4ac6c 232 SMART SM00418 6 88 0.0012 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_10045 d362c78ab4bd9eb0eb46684fd2f4ac6c 232 SUPERFAMILY SSF46785 1 203 1.36E-26 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_10045 d362c78ab4bd9eb0eb46684fd2f4ac6c 232 Gene3D G3DSA:3.30.1380.20 82 226 9.0E-6 T 11-10-2018 AFK25_11770 c8925415fb29413e846fb3ea59cb3cab 399 SUPERFAMILY SSF53822 41 394 7.07E-74 T 11-10-2018 IPR028082 Periplasmic binding protein-like I AFK25_11770 c8925415fb29413e846fb3ea59cb3cab 399 Pfam PF13458 Periplasmic binding protein 41 389 1.9E-78 T 11-10-2018 IPR028081 Leucine-binding protein domain AFK25_11770 c8925415fb29413e846fb3ea59cb3cab 399 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 64 80 1.8E-6 T 11-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFK25_11770 c8925415fb29413e846fb3ea59cb3cab 399 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 42 58 1.8E-6 T 11-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFK25_11770 c8925415fb29413e846fb3ea59cb3cab 399 PRINTS PR00337 Leu/Ile/Val-binding protein family signature 272 290 1.8E-6 T 11-10-2018 IPR000709 Leu/Ile/Val-binding protein GO:0006865 AFK25_11770 c8925415fb29413e846fb3ea59cb3cab 399 Gene3D G3DSA:3.40.50.2300 42 378 4.0E-123 T 11-10-2018 AFK25_11770 c8925415fb29413e846fb3ea59cb3cab 399 Gene3D G3DSA:3.40.50.2300 159 385 4.0E-123 T 11-10-2018 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 Pfam PF01367 5'-3' exonuclease, C-terminal SAM fold 172 265 1.2E-34 T 11-10-2018 IPR020045 DNA polymerase I-like, H3TH domain GO:0003677|GO:0003824 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 SMART SM00474 298 465 1.1E-15 T 11-10-2018 IPR002562 3'-5' exonuclease domain GO:0003676|GO:0006139|GO:0008408 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 SUPERFAMILY SSF56672 469 875 7.12E-160 T 11-10-2018 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 SUPERFAMILY SSF53098 306 466 1.97E-44 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 SMART SM00475 3 262 7.0E-159 T 11-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 Pfam PF02739 5'-3' exonuclease, N-terminal resolvase-like domain 4 170 5.9E-56 T 11-10-2018 IPR020046 5'-3' exonuclease, alpha-helical arch, N-terminal GO:0003677 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 SUPERFAMILY SSF88723 2 170 3.08E-58 T 11-10-2018 IPR029060 PIN-like domain superfamily AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 TIGRFAM TIGR00593 pola: DNA polymerase I 5 875 0.0 T 11-10-2018 IPR018320 DNA polymerase 1 GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 SMART SM00482 632 839 2.5E-119 T 11-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 Gene3D G3DSA:1.10.150.20 656 799 1.2E-111 T 11-10-2018 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 Gene3D G3DSA:3.40.50.1010 5 278 6.7E-103 T 11-10-2018 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 SMART SM00279 173 208 7.9E-17 T 11-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 Gene3D G3DSA:3.30.70.370 610 871 1.2E-111 T 11-10-2018 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 Pfam PF00476 DNA polymerase family A 498 873 1.2E-161 T 11-10-2018 IPR001098 DNA-directed DNA polymerase, family A, palm domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 Gene3D G3DSA:1.10.150.20 174 247 6.7E-103 T 11-10-2018 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 601 623 8.7E-83 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 701 726 8.7E-83 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 822 835 8.7E-83 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 677 690 8.7E-83 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 647 670 8.7E-83 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 738 749 8.7E-83 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 792 808 8.7E-83 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 624 639 8.7E-83 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 PRINTS PR00868 DNA-polymerase family A (pol I) signature 760 771 8.7E-83 T 11-10-2018 IPR002298 DNA polymerase A GO:0003887|GO:0006261 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 SUPERFAMILY SSF47807 171 285 7.18E-36 T 11-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 Gene3D G3DSA:3.30.420.10 296 489 1.0E-67 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 Gene3D G3DSA:1.20.1060.10 490 604 1.2E-46 T 11-10-2018 AFK25_11585 73dc763a211b0f3b3f292bc79bc8ccfd 875 ProSitePatterns PS00447 DNA polymerase family A signature. 701 720 - T 11-10-2018 IPR019760 DNA-directed DNA polymerase, family A, conserved site GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_11945 f3a3b5e2c48c3147fad6a08e568c1fe7 355 Gene3D G3DSA:2.40.30.40 72 159 5.6E-122 T 11-10-2018 IPR023367 Peptidase M42, domain 2 AFK25_11945 f3a3b5e2c48c3147fad6a08e568c1fe7 355 Pfam PF05343 M42 glutamyl aminopeptidase 43 335 3.3E-114 T 11-10-2018 IPR008007 Peptidase M42 AFK25_11945 f3a3b5e2c48c3147fad6a08e568c1fe7 355 Gene3D G3DSA:3.40.630.10 8 338 5.6E-122 T 11-10-2018 AFK25_11945 f3a3b5e2c48c3147fad6a08e568c1fe7 355 PIRSF PIRSF001123 1 354 1.7E-152 T 11-10-2018 IPR008007 Peptidase M42 AFK25_11945 f3a3b5e2c48c3147fad6a08e568c1fe7 355 SUPERFAMILY SSF101821 68 177 7.78E-31 T 11-10-2018 AFK25_11945 f3a3b5e2c48c3147fad6a08e568c1fe7 355 SUPERFAMILY SSF53187 3 349 2.66E-73 T 11-10-2018 AFK25_10910 74db419e635787667fc0f3de2b588bbd 428 Gene3D G3DSA:3.40.50.300 158 339 1.2E-62 T 11-10-2018 AFK25_10910 74db419e635787667fc0f3de2b588bbd 428 PIRSF PIRSF002401 1 376 1.3E-147 T 11-10-2018 IPR035101 GTP-binding protein, Obg-type AFK25_10910 74db419e635787667fc0f3de2b588bbd 428 Pfam PF01018 GTP1/OBG 3 157 6.6E-64 T 11-10-2018 IPR006169 GTP1/OBG domain AFK25_10910 74db419e635787667fc0f3de2b588bbd 428 TIGRFAM TIGR03595 Obg_CgtA_exten: Obg family GTPase CgtA, C-terminal extension 358 427 1.6E-27 T 11-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 AFK25_10910 74db419e635787667fc0f3de2b588bbd 428 Gene3D G3DSA:2.40.240.60 356 428 1.8E-18 T 11-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily AFK25_10910 74db419e635787667fc0f3de2b588bbd 428 Gene3D G3DSA:2.70.210.12 1 157 6.3E-65 T 11-10-2018 IPR036726 GTP1/OBG domain superfamily AFK25_10910 74db419e635787667fc0f3de2b588bbd 428 TIGRFAM TIGR02729 Obg_CgtA: Obg family GTPase CgtA 2 328 6.2E-148 T 11-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 AFK25_10910 74db419e635787667fc0f3de2b588bbd 428 Hamap MF_01454 GTPase Obg [obg]. 1 329 49.583 T 11-10-2018 IPR014100 GTP-binding protein Obg/CgtA GO:0000287|GO:0003924|GO:0005525 AFK25_10910 74db419e635787667fc0f3de2b588bbd 428 SUPERFAMILY SSF52540 160 342 1.58E-54 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_10910 74db419e635787667fc0f3de2b588bbd 428 SUPERFAMILY SSF102741 355 428 2.48E-24 T 11-10-2018 IPR036346 GTP-binding protein OBG, C-terminal domain superfamily AFK25_10910 74db419e635787667fc0f3de2b588bbd 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 161 181 3.0E-35 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_10910 74db419e635787667fc0f3de2b588bbd 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 182 200 3.0E-35 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_10910 74db419e635787667fc0f3de2b588bbd 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 210 225 3.0E-35 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_10910 74db419e635787667fc0f3de2b588bbd 428 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 227 245 3.0E-35 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_10910 74db419e635787667fc0f3de2b588bbd 428 Pfam PF01926 50S ribosome-binding GTPase 160 283 2.7E-23 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_10910 74db419e635787667fc0f3de2b588bbd 428 ProSitePatterns PS00905 GTP1/OBG family signature. 212 225 - T 11-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 AFK25_10910 74db419e635787667fc0f3de2b588bbd 428 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 160 320 4.5E-15 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFK25_10910 74db419e635787667fc0f3de2b588bbd 428 SUPERFAMILY SSF82051 1 157 7.59E-59 T 11-10-2018 IPR036726 GTP1/OBG domain superfamily AFK25_10910 74db419e635787667fc0f3de2b588bbd 428 Pfam PF09269 Domain of unknown function (DUF1967) 358 426 2.3E-26 T 11-10-2018 IPR015349 GTP-binding protein OBG, C-terminal GO:0000166 AFK25_08270 6d45c377cbb20ae2d9513dd44ad77c44 270 Gene3D G3DSA:3.40.50.620 2 267 1.5E-86 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_08270 6d45c377cbb20ae2d9513dd44ad77c44 270 SMART SM00893 23 218 1.1E-54 T 11-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFK25_08270 6d45c377cbb20ae2d9513dd44ad77c44 270 SUPERFAMILY SSF52402 2 262 2.51E-71 T 11-10-2018 AFK25_08270 6d45c377cbb20ae2d9513dd44ad77c44 270 PIRSF PIRSF000090 2 268 2.7E-86 T 11-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 AFK25_08270 6d45c377cbb20ae2d9513dd44ad77c44 270 Pfam PF01012 Electron transfer flavoprotein domain 24 214 1.2E-44 T 11-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFK25_12565 12c8af0c816a693aca3a8a48685f3fe0 331 Hamap MF_01685 Ferredoxin--NADP reductase. 7 329 44.749 T 11-10-2018 IPR022890 Ferredoxin--NADP reductase, type 2 GO:0004324|GO:0055114 KEGG: 00195+1.18.1.2|MetaCyc: PWY-101 AFK25_12565 12c8af0c816a693aca3a8a48685f3fe0 331 Gene3D G3DSA:3.50.50.60 128 247 3.0E-117 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_12565 12c8af0c816a693aca3a8a48685f3fe0 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 113 121 9.5E-25 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_12565 12c8af0c816a693aca3a8a48685f3fe0 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 9 31 9.5E-25 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_12565 12c8af0c816a693aca3a8a48685f3fe0 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 276 294 9.5E-25 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_12565 12c8af0c816a693aca3a8a48685f3fe0 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 66 76 9.5E-25 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_12565 12c8af0c816a693aca3a8a48685f3fe0 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 152 176 9.5E-25 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_12565 12c8af0c816a693aca3a8a48685f3fe0 331 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 203 219 9.5E-25 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_12565 12c8af0c816a693aca3a8a48685f3fe0 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 1.7E-17 T 11-10-2018 AFK25_12565 12c8af0c816a693aca3a8a48685f3fe0 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 156 174 1.7E-17 T 11-10-2018 AFK25_12565 12c8af0c816a693aca3a8a48685f3fe0 331 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 266 288 1.7E-17 T 11-10-2018 AFK25_12565 12c8af0c816a693aca3a8a48685f3fe0 331 Gene3D G3DSA:3.50.50.60 8 305 3.0E-117 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_12565 12c8af0c816a693aca3a8a48685f3fe0 331 SUPERFAMILY SSF51905 8 314 8.19E-43 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_12565 12c8af0c816a693aca3a8a48685f3fe0 331 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 294 1.3E-32 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFK25_01425 98e0e36a28e7b8e55052e23a0d2cf7bd 100 Gene3D G3DSA:1.10.10.10 3 98 7.5E-26 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_01425 98e0e36a28e7b8e55052e23a0d2cf7bd 100 SMART SM00418 14 93 5.3E-24 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_01425 98e0e36a28e7b8e55052e23a0d2cf7bd 100 SMART SM00419 28 78 0.0026 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFK25_01425 98e0e36a28e7b8e55052e23a0d2cf7bd 100 SUPERFAMILY SSF46785 10 93 1.48E-23 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_01425 98e0e36a28e7b8e55052e23a0d2cf7bd 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 16 31 1.3E-14 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_01425 98e0e36a28e7b8e55052e23a0d2cf7bd 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 64 79 1.3E-14 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_01425 98e0e36a28e7b8e55052e23a0d2cf7bd 100 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 49 64 1.3E-14 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_01425 98e0e36a28e7b8e55052e23a0d2cf7bd 100 Pfam PF01022 Bacterial regulatory protein, arsR family 21 67 7.6E-15 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_08600 f907b6a292266885569e70cfcba02d72 398 Gene3D G3DSA:3.90.1150.10 40 384 6.5E-140 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_08600 f907b6a292266885569e70cfcba02d72 398 SUPERFAMILY SSF53383 19 396 9.34E-113 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_08600 f907b6a292266885569e70cfcba02d72 398 Pfam PF00155 Aminotransferase class I and II 47 387 1.5E-65 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFK25_08600 f907b6a292266885569e70cfcba02d72 398 TIGRFAM TIGR00858 bioF: 8-amino-7-oxononanoate synthase 32 387 1.5E-146 T 11-10-2018 IPR004723 8-amino-7-oxononanoate synthase, Archaea/Proteobacteria type GO:0008710|GO:0009102 KEGG: 00780+2.3.1.47|MetaCyc: PWY-6519|MetaCyc: PWY-6578|MetaCyc: PWY-7147 AFK25_08600 f907b6a292266885569e70cfcba02d72 398 Gene3D G3DSA:3.40.640.10 61 295 6.5E-140 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_08600 f907b6a292266885569e70cfcba02d72 398 ProSitePatterns PS00599 Aminotransferases class-II pyridoxal-phosphate attachment site. 242 251 - T 11-10-2018 IPR001917 Aminotransferase, class-II, pyridoxal-phosphate binding site GO:0016740 AFK25_06660 bdc04791a869cd742f20fbd7b4405e4e 97 Gene3D G3DSA:1.10.1660.10 4 86 3.3E-20 T 11-10-2018 AFK25_06660 bdc04791a869cd742f20fbd7b4405e4e 97 ProSitePatterns PS00552 MerR-type HTH domain signature. 15 37 - T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_06660 bdc04791a869cd742f20fbd7b4405e4e 97 SMART SM00422 12 79 4.4E-15 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_06660 bdc04791a869cd742f20fbd7b4405e4e 97 Pfam PF13411 MerR HTH family regulatory protein 13 74 1.5E-14 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_06660 bdc04791a869cd742f20fbd7b4405e4e 97 SUPERFAMILY SSF46955 11 77 4.4E-16 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily AFK25_09895 cca165507d5b07b1414a97e221c744b6 170 PIRSF PIRSF021435 1 170 4.4E-60 T 11-10-2018 IPR014198 Stage III sporulation protein AB AFK25_09895 cca165507d5b07b1414a97e221c744b6 170 Pfam PF09548 Stage III sporulation protein AB (spore_III_AB) 2 170 8.5E-51 T 11-10-2018 IPR014198 Stage III sporulation protein AB AFK25_09895 cca165507d5b07b1414a97e221c744b6 170 TIGRFAM TIGR02833 spore_III_AB: stage III sporulation protein AB 2 170 3.3E-61 T 11-10-2018 IPR014198 Stage III sporulation protein AB AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 Gene3D G3DSA:3.50.50.60 77 398 1.1E-107 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 Gene3D G3DSA:3.30.390.30 413 538 1.7E-43 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 Gene3D G3DSA:3.30.70.100 3 70 6.4E-13 T 11-10-2018 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 SUPERFAMILY SSF51905 77 446 6.57E-57 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 ProSitePatterns PS01047 Heavy-metal-associated domain. 8 36 - T 11-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 PIRSF PIRSF000350 1 538 1.2E-243 T 11-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 Gene3D G3DSA:3.50.50.60 216 337 1.1E-107 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 414 521 4.4E-33 T 11-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 77 526 1.5E-123 T 11-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 243 268 2.0E-68 T 11-10-2018 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 475 490 2.0E-68 T 11-10-2018 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 207 216 2.0E-68 T 11-10-2018 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 110 125 2.0E-68 T 11-10-2018 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 374 381 2.0E-68 T 11-10-2018 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 78 100 2.0E-68 T 11-10-2018 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 410 431 2.0E-68 T 11-10-2018 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 497 517 2.0E-68 T 11-10-2018 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 331 345 2.0E-68 T 11-10-2018 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 111 121 - T 11-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 TIGRFAM TIGR02053 MerA: mercury(II) reductase 77 538 1.3E-190 T 11-10-2018 IPR021179 Mercury(II) reductase GO:0016152|GO:0016491|GO:0045340|GO:0050660|GO:0050661|GO:0050787|GO:0055114 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 Pfam PF00403 Heavy-metal-associated domain 6 63 8.9E-6 T 11-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 SUPERFAMILY SSF55008 1 65 6.68E-10 T 11-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 79 98 7.1E-30 T 11-10-2018 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 330 346 7.1E-30 T 11-10-2018 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 243 261 7.1E-30 T 11-10-2018 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 359 381 7.1E-30 T 11-10-2018 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 204 222 7.1E-30 T 11-10-2018 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 SUPERFAMILY SSF55424 413 535 9.97E-37 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFK25_07380 27f776025dbad492a0ac48b7bec8a74c 538 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 77 394 1.6E-72 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFK25_05520 393f838de5a25d84c824db4f459b6aac 78 SUPERFAMILY SSF47336 2 77 4.45E-23 T 11-10-2018 IPR036736 ACP-like superfamily AFK25_05520 393f838de5a25d84c824db4f459b6aac 78 Gene3D G3DSA:1.10.1200.10 1 75 1.3E-28 T 11-10-2018 IPR036736 ACP-like superfamily AFK25_05520 393f838de5a25d84c824db4f459b6aac 78 ProDom PD000887 CARRIER ACYL PHOSPHOPANTETHEINE ACP ACID FATTY BIOSYNTHESIS LIPID SYNTHESIS CHLOROPLAST 55 77 8.0E-6 T 11-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 AFK25_05520 393f838de5a25d84c824db4f459b6aac 78 ProSitePatterns PS00012 Phosphopantetheine attachment site. 32 47 - T 11-10-2018 IPR006162 Phosphopantetheine attachment site AFK25_05520 393f838de5a25d84c824db4f459b6aac 78 Hamap MF_01217 Acyl carrier protein [acpP]. 3 77 23.053 T 11-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 AFK25_05520 393f838de5a25d84c824db4f459b6aac 78 TIGRFAM TIGR00517 acyl_carrier: acyl carrier protein 2 76 4.3E-35 T 11-10-2018 IPR003231 Acyl carrier protein (ACP) GO:0006633 Reactome: R-HSA-389661|Reactome: R-HSA-611105|Reactome: R-HSA-6799198|Reactome: R-HSA-77289 AFK25_05520 393f838de5a25d84c824db4f459b6aac 78 Pfam PF00550 Phosphopantetheine attachment site 6 73 2.9E-14 T 11-10-2018 IPR009081 Phosphopantetheine binding ACP domain AFK25_11295 d50a3ae40553077ec341aaf2316dd36d 315 PRINTS PR01713 Nucleotide sugar epimerase signature 30 46 1.0E-17 T 11-10-2018 AFK25_11295 d50a3ae40553077ec341aaf2316dd36d 315 PRINTS PR01713 Nucleotide sugar epimerase signature 238 253 1.0E-17 T 11-10-2018 AFK25_11295 d50a3ae40553077ec341aaf2316dd36d 315 PRINTS PR01713 Nucleotide sugar epimerase signature 216 231 1.0E-17 T 11-10-2018 AFK25_11295 d50a3ae40553077ec341aaf2316dd36d 315 PRINTS PR01713 Nucleotide sugar epimerase signature 276 293 1.0E-17 T 11-10-2018 AFK25_11295 d50a3ae40553077ec341aaf2316dd36d 315 SUPERFAMILY SSF51735 1 313 2.86E-87 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_11295 d50a3ae40553077ec341aaf2316dd36d 315 Gene3D G3DSA:3.40.50.720 6 297 3.3E-95 T 11-10-2018 AFK25_11295 d50a3ae40553077ec341aaf2316dd36d 315 Pfam PF01370 NAD dependent epimerase/dehydratase family 4 244 4.8E-59 T 11-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFK25_11295 d50a3ae40553077ec341aaf2316dd36d 315 Gene3D G3DSA:3.90.25.10 181 309 3.3E-95 T 11-10-2018 AFK25_01330 5fc297be713168a550979d13a830ba30 200 Gene3D G3DSA:3.40.50.170 1 187 2.8E-76 T 11-10-2018 AFK25_01330 5fc297be713168a550979d13a830ba30 200 Hamap MF_01930 Phosphoribosylglycinamide formyltransferase [purN]. 3 188 31.779 T 11-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 AFK25_01330 5fc297be713168a550979d13a830ba30 200 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 134 157 - T 11-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFK25_01330 5fc297be713168a550979d13a830ba30 200 SUPERFAMILY SSF53328 2 189 1.44E-60 T 11-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFK25_01330 5fc297be713168a550979d13a830ba30 200 TIGRFAM TIGR00639 PurN: phosphoribosylglycinamide formyltransferase 2 189 9.4E-76 T 11-10-2018 IPR004607 Phosphoribosylglycinamide formyltransferase GO:0004644|GO:0006189 KEGG: 00230+2.1.2.2|KEGG: 00670+2.1.2.2|MetaCyc: PWY-6121|MetaCyc: PWY-6613|Reactome: R-HSA-73817 AFK25_01330 5fc297be713168a550979d13a830ba30 200 Pfam PF00551 Formyl transferase 2 182 6.2E-63 T 11-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFK25_10300 0debb1e2507ad01c5015b078bcd317a0 253 Gene3D G3DSA:3.30.60.100 146 185 1.6E-21 T 11-10-2018 AFK25_10300 0debb1e2507ad01c5015b078bcd317a0 253 Pfam PF11967 Recombination protein O N terminal 1 77 1.3E-24 T 11-10-2018 IPR022572 DNA replication/recombination mediator RecO, N-terminal AFK25_10300 0debb1e2507ad01c5015b078bcd317a0 253 TIGRFAM TIGR00613 reco: DNA repair protein RecO 4 243 9.6E-79 T 11-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 AFK25_10300 0debb1e2507ad01c5015b078bcd317a0 253 Gene3D G3DSA:2.40.50.140 2 81 5.3E-14 T 11-10-2018 AFK25_10300 0debb1e2507ad01c5015b078bcd317a0 253 SUPERFAMILY SSF50249 1 76 6.34E-19 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_10300 0debb1e2507ad01c5015b078bcd317a0 253 Hamap MF_00201 DNA repair protein RecO [recO]. 1 243 31.177 T 11-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 AFK25_10300 0debb1e2507ad01c5015b078bcd317a0 253 SUPERFAMILY SSF57863 80 232 1.52E-50 T 11-10-2018 IPR037278 ARFGAP/RecO-like zinc finger AFK25_10300 0debb1e2507ad01c5015b078bcd317a0 253 Pfam PF02565 Recombination protein O C terminal 82 237 4.1E-45 T 11-10-2018 IPR003717 Recombination protein O, RecO GO:0006281|GO:0006310 AFK25_10300 0debb1e2507ad01c5015b078bcd317a0 253 Gene3D G3DSA:1.20.1440.120 88 225 1.6E-21 T 11-10-2018 AFK25_03040 a720c1389f7c6fae1f280beb5ebcf126 387 Pfam PF00149 Calcineurin-like phosphoesterase 1 223 3.1E-13 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFK25_03040 a720c1389f7c6fae1f280beb5ebcf126 387 Gene3D G3DSA:3.60.21.10 1 270 3.3E-79 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like AFK25_03040 a720c1389f7c6fae1f280beb5ebcf126 387 TIGRFAM TIGR00619 sbcd: exonuclease SbcCD, D subunit 1 252 2.1E-75 T 11-10-2018 IPR004593 Nuclease SbcCD subunit D GO:0004519|GO:0006259|GO:0008408 AFK25_03040 a720c1389f7c6fae1f280beb5ebcf126 387 SUPERFAMILY SSF56300 1 327 2.66E-53 T 11-10-2018 AFK25_06580 fb479a62a1d3b15792f5b22ba46a99f9 507 Gene3D G3DSA:1.20.200.10 196 500 8.7E-125 T 11-10-2018 AFK25_06580 fb479a62a1d3b15792f5b22ba46a99f9 507 ProSitePatterns PS00488 Phenylalanine and histidine ammonia-lyases signature. 137 153 - T 11-10-2018 IPR022313 Phenylalanine/histidine ammonia-lyases, active site GO:0016841 Reactome: R-HSA-70921 AFK25_06580 fb479a62a1d3b15792f5b22ba46a99f9 507 Hamap MF_00229 Histidine ammonia-lyase [hutH]. 1 500 46.093 T 11-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFK25_06580 fb479a62a1d3b15792f5b22ba46a99f9 507 Gene3D G3DSA:1.10.275.10 1 195 4.3E-70 T 11-10-2018 IPR024083 Fumarase/histidase, N-terminal AFK25_06580 fb479a62a1d3b15792f5b22ba46a99f9 507 Pfam PF00221 Aromatic amino acid lyase 9 467 1.5E-198 T 11-10-2018 IPR001106 Aromatic amino acid lyase Reactome: R-HSA-70921 AFK25_06580 fb479a62a1d3b15792f5b22ba46a99f9 507 TIGRFAM TIGR01225 hutH: histidine ammonia-lyase 2 491 1.5E-219 T 11-10-2018 IPR005921 Histidine ammonia-lyase GO:0004397|GO:0005737|GO:0006548 KEGG: 00340+4.3.1.3|MetaCyc: PWY-5028|MetaCyc: PWY-5030|Reactome: R-HSA-70921 AFK25_06580 fb479a62a1d3b15792f5b22ba46a99f9 507 SUPERFAMILY SSF48557 2 493 2.9E-198 T 11-10-2018 IPR008948 L-Aspartase-like GO:0003824 AFK25_06985 a7507368e0701bf58e230cd34b869ca8 187 Gene3D G3DSA:3.20.20.400 1 184 4.7E-69 T 11-10-2018 IPR035928 GlpP-like superfamily AFK25_06985 a7507368e0701bf58e230cd34b869ca8 187 SUPERFAMILY SSF110391 6 179 2.09E-61 T 11-10-2018 IPR035928 GlpP-like superfamily AFK25_06985 a7507368e0701bf58e230cd34b869ca8 187 PIRSF PIRSF016897 1 183 6.8E-64 T 11-10-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 AFK25_06985 a7507368e0701bf58e230cd34b869ca8 187 Pfam PF04309 Glycerol-3-phosphate responsive antiterminator 6 178 3.3E-63 T 11-10-2018 IPR006699 Glycerol uptake operon antiterminator GO:0006071|GO:0006355 AFK25_13140 5569d72715bd2d05debeb1190a9c4e2f 182 Hamap MF_00839 Ribosome hibernation promoting factor [hpf]. 1 182 25.978 T 11-10-2018 IPR034694 Ribosome hibernation promoting factor, long/plastid AFK25_13140 5569d72715bd2d05debeb1190a9c4e2f 182 Gene3D G3DSA:3.30.160.100 1 99 1.1E-33 T 11-10-2018 IPR036567 Ribosome hibernation promotion factor-like AFK25_13140 5569d72715bd2d05debeb1190a9c4e2f 182 TIGRFAM TIGR00741 yfiA: ribosomal subunit interface protein 1 102 1.2E-35 T 11-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 AFK25_13140 5569d72715bd2d05debeb1190a9c4e2f 182 SUPERFAMILY SSF69754 2 106 9.29E-35 T 11-10-2018 IPR036567 Ribosome hibernation promotion factor-like AFK25_13140 5569d72715bd2d05debeb1190a9c4e2f 182 Gene3D G3DSA:3.30.505.50 136 182 1.4E-27 T 11-10-2018 IPR038416 Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain superfamily AFK25_13140 5569d72715bd2d05debeb1190a9c4e2f 182 Pfam PF16321 Sigma 54 modulation/S30EA ribosomal protein C terminus 122 178 6.5E-31 T 11-10-2018 IPR032528 Sigma 54 modulation/S30EA ribosomal protein, C-terminal AFK25_13140 5569d72715bd2d05debeb1190a9c4e2f 182 Pfam PF02482 Sigma 54 modulation protein / S30EA ribosomal protein 3 95 3.9E-32 T 11-10-2018 IPR003489 Ribosome hibernation promoting factor/RaiA GO:0044238 AFK25_07455 5a0753da61190cdf086d0d37d1f03b04 306 SUPERFAMILY SSF90002 217 301 7.06E-12 T 11-10-2018 AFK25_07455 5a0753da61190cdf086d0d37d1f03b04 306 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 217 301 4.2E-14 T 11-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AFK25_07455 5a0753da61190cdf086d0d37d1f03b04 306 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 6 183 4.0E-45 T 11-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain AFK25_07455 5a0753da61190cdf086d0d37d1f03b04 306 SUPERFAMILY SSF52540 6 178 6.43E-27 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_07455 5a0753da61190cdf086d0d37d1f03b04 306 Gene3D G3DSA:3.40.50.300 1 200 7.8E-52 T 11-10-2018 AFK25_07455 5a0753da61190cdf086d0d37d1f03b04 306 SMART SM00833 217 302 1.3E-12 T 11-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AFK25_07455 5a0753da61190cdf086d0d37d1f03b04 306 Gene3D G3DSA:3.30.1220.10 201 303 1.1E-7 T 11-10-2018 IPR036627 CobW-like, C-terminal domain superfamily AFK25_12575 69ec85038eafcd0532679b0e10dc8145 120 TIGRFAM TIGR00049 TIGR00049: iron-sulfur cluster assembly accessory protein 5 109 1.9E-37 T 11-10-2018 IPR016092 FeS cluster insertion protein GO:0005198|GO:0051536|GO:0097428 Reactome: R-HSA-1362409 AFK25_12575 69ec85038eafcd0532679b0e10dc8145 120 SUPERFAMILY SSF89360 3 96 4.9E-29 T 11-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 AFK25_12575 69ec85038eafcd0532679b0e10dc8145 120 ProSitePatterns PS01152 Hypothetical hesB/yadR/yfhF family signature. 91 108 - T 11-10-2018 IPR017870 FeS cluster insertion, C-terminal, conserved site Reactome: R-HSA-1362409 AFK25_12575 69ec85038eafcd0532679b0e10dc8145 120 Pfam PF01521 Iron-sulphur cluster biosynthesis 6 105 3.9E-19 T 11-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 AFK25_12575 69ec85038eafcd0532679b0e10dc8145 120 Gene3D G3DSA:2.60.300.12 4 112 3.7E-36 T 11-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 AFK25_04280 bbe5f56bf0449278ac79005da3a03592 338 Pfam PF00356 Bacterial regulatory proteins, lacI family 3 48 2.7E-20 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_04280 bbe5f56bf0449278ac79005da3a03592 338 SUPERFAMILY SSF47413 2 59 4.96E-20 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFK25_04280 bbe5f56bf0449278ac79005da3a03592 338 Pfam PF13377 Periplasmic binding protein-like domain 173 332 6.3E-45 T 11-10-2018 AFK25_04280 bbe5f56bf0449278ac79005da3a03592 338 Gene3D G3DSA:1.10.260.40 1 59 6.5E-24 T 11-10-2018 AFK25_04280 bbe5f56bf0449278ac79005da3a03592 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 3.0E-6 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_04280 bbe5f56bf0449278ac79005da3a03592 338 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 3.0E-6 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_04280 bbe5f56bf0449278ac79005da3a03592 338 SUPERFAMILY SSF53822 60 334 6.93E-85 T 11-10-2018 IPR028082 Periplasmic binding protein-like I AFK25_04280 bbe5f56bf0449278ac79005da3a03592 338 Gene3D G3DSA:3.40.50.2300 164 330 6.9E-85 T 11-10-2018 AFK25_04280 bbe5f56bf0449278ac79005da3a03592 338 SMART SM00354 1 71 2.5E-31 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_04280 bbe5f56bf0449278ac79005da3a03592 338 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 11-10-2018 AFK25_04280 bbe5f56bf0449278ac79005da3a03592 338 Gene3D G3DSA:3.40.50.2300 76 324 6.9E-85 T 11-10-2018 AFK25_13965 32643b1e9a7b65b42c6c1f3d042e397e 215 TIGRFAM TIGR00875 fsa_talC_mipB: fructose-6-phosphate aldolase 1 212 1.1E-105 T 11-10-2018 IPR004731 Transaldolase type 3B/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 AFK25_13965 32643b1e9a7b65b42c6c1f3d042e397e 215 ProSitePatterns PS00958 Transaldolase active site. 80 97 - T 11-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 AFK25_13965 32643b1e9a7b65b42c6c1f3d042e397e 215 Pfam PF00923 Transaldolase/Fructose-6-phosphate aldolase 3 210 1.1E-57 T 11-10-2018 IPR001585 Transaldolase/Fructose-6-phosphate aldolase GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 AFK25_13965 32643b1e9a7b65b42c6c1f3d042e397e 215 Hamap MF_00494 Probable transaldolase [tal]. 1 214 47.734 T 11-10-2018 IPR022999 Transaldolase type 3B, putative GO:0004801 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723 AFK25_13965 32643b1e9a7b65b42c6c1f3d042e397e 215 Gene3D G3DSA:3.20.20.70 1 215 2.2E-90 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_13965 32643b1e9a7b65b42c6c1f3d042e397e 215 SUPERFAMILY SSF51569 1 212 5.76E-80 T 11-10-2018 AFK25_13965 32643b1e9a7b65b42c6c1f3d042e397e 215 ProSitePatterns PS01054 Transaldolase signature 1. 24 32 - T 11-10-2018 IPR018225 Transaldolase, active site GO:0005975 KEGG: 00030+2.2.1.2|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-163754|Reactome: R-HSA-6791055|Reactome: R-HSA-6791462|Reactome: R-HSA-71336|Reactome: R-HSA-8950505 AFK25_11230 3d30db1b6f0c0c28b3eec480d62428f2 69 Pfam PF00196 Bacterial regulatory proteins, luxR family 7 59 4.8E-24 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_11230 3d30db1b6f0c0c28b3eec480d62428f2 69 SUPERFAMILY SSF46894 5 67 4.76E-23 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFK25_11230 3d30db1b6f0c0c28b3eec480d62428f2 69 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 7 21 1.4E-12 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_11230 3d30db1b6f0c0c28b3eec480d62428f2 69 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 37 49 1.4E-12 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_11230 3d30db1b6f0c0c28b3eec480d62428f2 69 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 21 37 1.4E-12 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_11230 3d30db1b6f0c0c28b3eec480d62428f2 69 SMART SM00421 4 61 4.4E-25 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_11230 3d30db1b6f0c0c28b3eec480d62428f2 69 Gene3D G3DSA:1.10.10.10 1 69 1.1E-27 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_11230 3d30db1b6f0c0c28b3eec480d62428f2 69 ProSitePatterns PS00622 LuxR-type HTH domain signature. 21 48 - T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_11485 066d42edc3d9bc5ffede27b360b740ab 747 ProSitePatterns PS00512 Alpha-galactosidase signature. 362 377 - T 11-10-2018 IPR000111 Glycoside hydrolase family 27/36, conserved site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFK25_11485 066d42edc3d9bc5ffede27b360b740ab 747 SUPERFAMILY SSF51445 327 670 1.44E-112 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily AFK25_11485 066d42edc3d9bc5ffede27b360b740ab 747 Gene3D G3DSA:2.70.98.60 1 312 5.5E-118 T 11-10-2018 IPR038417 Alpha-galactosidase, N-terminal domain superfamily KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFK25_11485 066d42edc3d9bc5ffede27b360b740ab 747 Pfam PF16875 Glycosyl hydrolase family 36 N-terminal domain 29 287 4.2E-90 T 11-10-2018 IPR031704 Glycosyl hydrolase family 36, N-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFK25_11485 066d42edc3d9bc5ffede27b360b740ab 747 Pfam PF02065 Melibiase 292 639 2.3E-161 T 11-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFK25_11485 066d42edc3d9bc5ffede27b360b740ab 747 Pfam PF16874 Glycosyl hydrolase family 36 C-terminal domain 653 742 7.3E-21 T 11-10-2018 IPR031705 Glycosyl hydrolase family 36, C-terminal KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFK25_11485 066d42edc3d9bc5ffede27b360b740ab 747 PIRSF PIRSF005536 1 746 3.1E-298 T 11-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFK25_11485 066d42edc3d9bc5ffede27b360b740ab 747 PRINTS PR00743 Glycosyl hydrolase family 36 signature 244 259 3.8E-60 T 11-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFK25_11485 066d42edc3d9bc5ffede27b360b740ab 747 PRINTS PR00743 Glycosyl hydrolase family 36 signature 549 565 3.8E-60 T 11-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFK25_11485 066d42edc3d9bc5ffede27b360b740ab 747 PRINTS PR00743 Glycosyl hydrolase family 36 signature 411 433 3.8E-60 T 11-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFK25_11485 066d42edc3d9bc5ffede27b360b740ab 747 PRINTS PR00743 Glycosyl hydrolase family 36 signature 295 315 3.8E-60 T 11-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFK25_11485 066d42edc3d9bc5ffede27b360b740ab 747 PRINTS PR00743 Glycosyl hydrolase family 36 signature 470 485 3.8E-60 T 11-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFK25_11485 066d42edc3d9bc5ffede27b360b740ab 747 PRINTS PR00743 Glycosyl hydrolase family 36 signature 361 376 3.8E-60 T 11-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFK25_11485 066d42edc3d9bc5ffede27b360b740ab 747 PRINTS PR00743 Glycosyl hydrolase family 36 signature 333 347 3.8E-60 T 11-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFK25_11485 066d42edc3d9bc5ffede27b360b740ab 747 PRINTS PR00743 Glycosyl hydrolase family 36 signature 524 540 3.8E-60 T 11-10-2018 IPR002252 Glycoside hydrolase family 36 GO:0004557|GO:0005975 KEGG: 00052+3.2.1.22|KEGG: 00561+3.2.1.22|KEGG: 00600+3.2.1.22|KEGG: 00603+3.2.1.22|MetaCyc: PWY-6527 AFK25_11485 066d42edc3d9bc5ffede27b360b740ab 747 Gene3D G3DSA:2.60.40.1180 637 747 2.2E-30 T 11-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFK25_11485 066d42edc3d9bc5ffede27b360b740ab 747 Gene3D G3DSA:3.20.20.70 313 636 3.4E-133 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_07130 9c02204bd72cac0de24126df090ead06 125 PIRSF PIRSF004761 1 118 6.7E-25 T 11-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 AFK25_07130 9c02204bd72cac0de24126df090ead06 125 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 1 113 3.8E-24 T 11-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 AFK25_07130 9c02204bd72cac0de24126df090ead06 125 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 116 17.215 T 11-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 AFK25_07130 9c02204bd72cac0de24126df090ead06 125 Gene3D G3DSA:3.30.2320.80 1 115 2.6E-25 T 11-10-2018 AFK25_09495 299419080d8d12c0b6be65b436bf2a67 1227 ProSitePatterns PS00932 Prokaryotic molybdopterin oxidoreductases signature 3. 1116 1143 - T 11-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 AFK25_09495 299419080d8d12c0b6be65b436bf2a67 1227 TIGRFAM TIGR01580 narG: nitrate reductase, alpha subunit 5 1226 0.0 T 11-10-2018 IPR006468 Nitrate reductase, alpha subunit GO:0008940|GO:0009325|GO:0042126|GO:0055114 KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 AFK25_09495 299419080d8d12c0b6be65b436bf2a67 1227 ProSitePatterns PS00490 Prokaryotic molybdopterin oxidoreductases signature 2. 767 784 - T 11-10-2018 IPR006655 Molybdopterin oxidoreductase, prokaryotic, conserved site GO:0009055|GO:0016491|GO:0055114 AFK25_09495 299419080d8d12c0b6be65b436bf2a67 1227 SUPERFAMILY SSF50692 1073 1225 2.1E-45 T 11-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFK25_09495 299419080d8d12c0b6be65b436bf2a67 1227 Pfam PF14710 Respiratory nitrate reductase alpha N-terminal 7 42 5.9E-12 T 11-10-2018 IPR028189 Nitrate reductase, alpha subunit, N-terminal KEGG: 00910+1.7.5.1|MetaCyc: PWY-6748 AFK25_09495 299419080d8d12c0b6be65b436bf2a67 1227 Gene3D G3DSA:3.40.50.12440 46 1227 0.0 T 11-10-2018 AFK25_09495 299419080d8d12c0b6be65b436bf2a67 1227 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 50 68 - T 11-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 AFK25_09495 299419080d8d12c0b6be65b436bf2a67 1227 Pfam PF01568 Molydopterin dinucleotide binding domain 1079 1193 1.2E-20 T 11-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AFK25_09495 299419080d8d12c0b6be65b436bf2a67 1227 SUPERFAMILY SSF53706 6 1064 0.0 T 11-10-2018 AFK25_09495 299419080d8d12c0b6be65b436bf2a67 1227 SMART SM00926 45 107 6.9E-8 T 11-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_09495 299419080d8d12c0b6be65b436bf2a67 1227 Pfam PF00384 Molybdopterin oxidoreductase 110 823 6.3E-175 T 11-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_02145 b5c067c183e0c1f5812489988be39d6a 251 Pfam PF01695 IstB-like ATP binding protein 53 228 5.8E-72 T 11-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 AFK25_02145 b5c067c183e0c1f5812489988be39d6a 251 PIRSF PIRSF003073 1 251 1.3E-85 T 11-10-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein AFK25_02145 b5c067c183e0c1f5812489988be39d6a 251 SUPERFAMILY SSF52540 64 225 2.51E-28 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_02145 b5c067c183e0c1f5812489988be39d6a 251 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 188 202 3.9E-5 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_02145 b5c067c183e0c1f5812489988be39d6a 251 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 101 119 3.9E-5 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_02145 b5c067c183e0c1f5812489988be39d6a 251 Gene3D G3DSA:3.40.50.300 61 248 4.1E-58 T 11-10-2018 AFK25_02145 b5c067c183e0c1f5812489988be39d6a 251 SMART SM00382 97 229 1.2E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_10580 b5c067c183e0c1f5812489988be39d6a 251 Pfam PF01695 IstB-like ATP binding protein 53 228 5.8E-72 T 11-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 AFK25_10580 b5c067c183e0c1f5812489988be39d6a 251 PIRSF PIRSF003073 1 251 1.3E-85 T 11-10-2018 IPR028350 DNA replication protein DnaC/insertion sequence putative ATP-binding protein AFK25_10580 b5c067c183e0c1f5812489988be39d6a 251 SUPERFAMILY SSF52540 64 225 2.51E-28 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_10580 b5c067c183e0c1f5812489988be39d6a 251 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 188 202 3.9E-5 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_10580 b5c067c183e0c1f5812489988be39d6a 251 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 101 119 3.9E-5 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_10580 b5c067c183e0c1f5812489988be39d6a 251 Gene3D G3DSA:3.40.50.300 61 248 4.1E-58 T 11-10-2018 AFK25_10580 b5c067c183e0c1f5812489988be39d6a 251 SMART SM00382 97 229 1.2E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_12610 ff16d4cb3b267dd2dfa27a8d70ba5e38 78 SUPERFAMILY SSF117916 3 77 4.74E-27 T 11-10-2018 IPR034904 Fe-S cluster assembly domain superfamily AFK25_12610 ff16d4cb3b267dd2dfa27a8d70ba5e38 78 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 14 65 2.0E-22 T 11-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 AFK25_12610 ff16d4cb3b267dd2dfa27a8d70ba5e38 78 Pfam PF01106 NifU-like domain 10 75 4.2E-28 T 11-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 AFK25_12610 ff16d4cb3b267dd2dfa27a8d70ba5e38 78 Gene3D G3DSA:3.30.300.130 1 78 7.6E-33 T 11-10-2018 IPR034904 Fe-S cluster assembly domain superfamily AFK25_07960 f24e694b5a589692163311adccea0b79 360 Pfam PF13407 Periplasmic binding protein domain 46 304 5.2E-70 T 11-10-2018 IPR025997 Periplasmic binding protein AFK25_07960 f24e694b5a589692163311adccea0b79 360 SUPERFAMILY SSF53822 42 333 6.63E-79 T 11-10-2018 IPR028082 Periplasmic binding protein-like I AFK25_07960 f24e694b5a589692163311adccea0b79 360 Gene3D G3DSA:3.40.50.2300 47 323 1.3E-122 T 11-10-2018 AFK25_07960 f24e694b5a589692163311adccea0b79 360 Gene3D G3DSA:3.40.50.2300 147 335 1.3E-122 T 11-10-2018 AFK25_07960 f24e694b5a589692163311adccea0b79 360 TIGRFAM TIGR02634 xylF: D-xylose ABC transporter, D-xylose-binding protein 46 347 9.1E-132 T 11-10-2018 IPR013456 D-xylose ABC transporter, substrate-binding protein GO:0015753|GO:0048029 AFK25_04070 96a089aca0bc417658321711a52f4dc3 122 SUPERFAMILY SSF46785 20 112 1.2E-26 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_04070 96a089aca0bc417658321711a52f4dc3 122 SMART SM00418 34 113 2.9E-31 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_04070 96a089aca0bc417658321711a52f4dc3 122 ProSitePatterns PS00846 Bacterial regulatory proteins, arsR family signature. 58 76 - T 11-10-2018 IPR018334 ArsR-type transcription regulator, HTH motif GO:0003700|GO:0005622|GO:0006355 AFK25_04070 96a089aca0bc417658321711a52f4dc3 122 Gene3D G3DSA:1.10.10.10 1 122 8.8E-40 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_04070 96a089aca0bc417658321711a52f4dc3 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 84 99 1.1E-21 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_04070 96a089aca0bc417658321711a52f4dc3 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 56 67 1.1E-21 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_04070 96a089aca0bc417658321711a52f4dc3 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 36 51 1.1E-21 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_04070 96a089aca0bc417658321711a52f4dc3 122 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 69 84 1.1E-21 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_04070 96a089aca0bc417658321711a52f4dc3 122 Pfam PF01022 Bacterial regulatory protein, arsR family 41 88 9.4E-17 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_07275 a83e49ec8025bd45571214d3a1203115 295 SMART SM00382 54 200 7.1E-5 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_07275 a83e49ec8025bd45571214d3a1203115 295 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 130 148 3.7E-5 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_07275 a83e49ec8025bd45571214d3a1203115 295 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 58 76 3.7E-5 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_07275 a83e49ec8025bd45571214d3a1203115 295 Gene3D G3DSA:3.40.50.300 40 212 6.5E-34 T 11-10-2018 AFK25_07275 a83e49ec8025bd45571214d3a1203115 295 SUPERFAMILY SSF52540 40 276 4.89E-38 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_07275 a83e49ec8025bd45571214d3a1203115 295 Pfam PF07728 AAA domain (dynein-related subfamily) 57 194 6.0E-26 T 11-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 AFK25_07275 a83e49ec8025bd45571214d3a1203115 295 Pfam PF08406 CbbQ/NirQ/NorQ C-terminal 209 289 9.9E-5 T 11-10-2018 IPR013615 CbbQ/NirQ/NorQ, C-terminal AFK25_00140 863f6b407b1525ab28218f2e78dec9a6 88 Pfam PF07441 SigmaK-factor processing regulatory protein BofA 12 84 2.5E-18 T 11-10-2018 IPR010001 SigmaK-factor processing regulatory BofA AFK25_00140 863f6b407b1525ab28218f2e78dec9a6 88 TIGRFAM TIGR02862 spore_BofA: pro-sigmaK processing inhibitor BofA 5 86 2.8E-21 T 11-10-2018 IPR010001 SigmaK-factor processing regulatory BofA AFK25_02650 9b7c45b6349d755320b061ec1858bd97 472 Pfam PF04293 SpoVR like protein 5 411 9.4E-165 T 11-10-2018 IPR007390 Sporulation stage V, protein R AFK25_10450 b036c07b23fc8edad2a5e07286416380 196 Gene3D G3DSA:3.10.560.10 44 142 1.5E-10 T 11-10-2018 AFK25_10450 b036c07b23fc8edad2a5e07286416380 196 Pfam PF10531 SLBB domain 58 111 4.3E-14 T 11-10-2018 IPR019554 Soluble ligand binding domain Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_10450 b036c07b23fc8edad2a5e07286416380 196 SMART SM00278 173 192 0.37 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFK25_10450 b036c07b23fc8edad2a5e07286416380 196 SMART SM00278 143 162 0.13 T 11-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AFK25_10450 b036c07b23fc8edad2a5e07286416380 196 Gene3D G3DSA:1.10.150.310 143 196 1.9E-16 T 11-10-2018 AFK25_10450 b036c07b23fc8edad2a5e07286416380 196 TIGRFAM TIGR00426 TIGR00426: competence protein ComEA helix-hairpin-helix repeat region 129 195 5.1E-29 T 11-10-2018 IPR004509 Competence protein ComEA, helix-hairpin-helix domain AFK25_10450 b036c07b23fc8edad2a5e07286416380 196 SUPERFAMILY SSF47781 130 195 5.11E-33 T 11-10-2018 IPR010994 RuvA domain 2-like AFK25_10450 b036c07b23fc8edad2a5e07286416380 196 Pfam PF12836 Helix-hairpin-helix motif 131 193 1.9E-26 T 11-10-2018 AFK25_04615 7d3b49353ecfe6e3eaf9c0f4fc9c5021 91 PIRSF PIRSF028784 1 89 1.7E-31 T 11-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 AFK25_04615 7d3b49353ecfe6e3eaf9c0f4fc9c5021 91 Pfam PF04066 Multiple resistance and pH regulation protein F (MrpF / PhaF) 28 80 9.1E-18 T 11-10-2018 IPR007208 Na(+)/H(+) antiporter subunit F-like GO:0015075|GO:0016021|GO:0034220 AFK25_12865 1a1751997f156d37f5561ef9f1a7b2a2 759 Pfam PF08206 Ribonuclease B OB domain 142 196 3.0E-10 T 11-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain AFK25_12865 1a1751997f156d37f5561ef9f1a7b2a2 759 Pfam PF08206 Ribonuclease B OB domain 69 127 6.0E-23 T 11-10-2018 IPR013223 Ribonuclease B, N-terminal OB domain AFK25_12865 1a1751997f156d37f5561ef9f1a7b2a2 759 SUPERFAMILY SSF50249 121 220 1.25E-21 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_12865 1a1751997f156d37f5561ef9f1a7b2a2 759 SUPERFAMILY SSF50249 621 703 8.21E-24 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_12865 1a1751997f156d37f5561ef9f1a7b2a2 759 SMART SM00955 243 573 1.3E-186 T 11-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 AFK25_12865 1a1751997f156d37f5561ef9f1a7b2a2 759 TIGRFAM TIGR00358 3_prime_RNase: VacB and RNase II family 3'-5' exoribonucleases 53 703 2.0E-254 T 11-10-2018 IPR004476 Ribonuclease II/ribonuclease R GO:0003723|GO:0004540|GO:0016070 AFK25_12865 1a1751997f156d37f5561ef9f1a7b2a2 759 SMART SM00357 68 128 1.2E-11 T 11-10-2018 IPR011129 Cold shock domain GO:0003676 AFK25_12865 1a1751997f156d37f5561ef9f1a7b2a2 759 SMART SM00357 133 197 1.8E-7 T 11-10-2018 IPR011129 Cold shock domain GO:0003676 AFK25_12865 1a1751997f156d37f5561ef9f1a7b2a2 759 Gene3D G3DSA:2.40.50.140 625 759 4.5E-26 T 11-10-2018 AFK25_12865 1a1751997f156d37f5561ef9f1a7b2a2 759 TIGRFAM TIGR02063 RNase_R: ribonuclease R 1 703 5.0E-292 T 11-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 AFK25_12865 1a1751997f156d37f5561ef9f1a7b2a2 759 SUPERFAMILY SSF50249 50 130 1.71E-18 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_12865 1a1751997f156d37f5561ef9f1a7b2a2 759 SMART SM00316 621 703 1.6E-18 T 11-10-2018 IPR022967 RNA-binding domain, S1 AFK25_12865 1a1751997f156d37f5561ef9f1a7b2a2 759 Pfam PF00575 S1 RNA binding domain 620 701 7.1E-15 T 11-10-2018 IPR003029 S1 domain GO:0003676 AFK25_12865 1a1751997f156d37f5561ef9f1a7b2a2 759 SUPERFAMILY SSF50249 203 620 2.4E-152 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_12865 1a1751997f156d37f5561ef9f1a7b2a2 759 Gene3D G3DSA:2.40.50.140 54 130 1.2E-20 T 11-10-2018 AFK25_12865 1a1751997f156d37f5561ef9f1a7b2a2 759 Gene3D G3DSA:2.40.50.140 132 198 2.5E-10 T 11-10-2018 AFK25_12865 1a1751997f156d37f5561ef9f1a7b2a2 759 Pfam PF00773 RNB domain 243 571 1.8E-116 T 11-10-2018 IPR001900 Ribonuclease II/R GO:0003723|GO:0004540 AFK25_12865 1a1751997f156d37f5561ef9f1a7b2a2 759 ProSitePatterns PS01175 Ribonuclease II family signature. 540 564 - T 11-10-2018 IPR022966 Ribonuclease II/R, conserved site AFK25_12865 1a1751997f156d37f5561ef9f1a7b2a2 759 Hamap MF_01895 Ribonuclease R [rnr]. 20 703 62.181 T 11-10-2018 IPR011805 Ribonuclease R GO:0003723|GO:0004518 AFK25_11310 1ae599a507d778275c5e38a5ebe8cb68 325 SUPERFAMILY SSF52467 198 317 5.86E-49 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFK25_11310 1ae599a507d778275c5e38a5ebe8cb68 325 Gene3D G3DSA:3.40.50.620 1 194 1.5E-54 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_11310 1ae599a507d778275c5e38a5ebe8cb68 325 Gene3D G3DSA:3.40.50.1220 195 325 8.2E-58 T 11-10-2018 AFK25_11310 1ae599a507d778275c5e38a5ebe8cb68 325 SUPERFAMILY SSF52402 4 190 9.07E-51 T 11-10-2018 AFK25_11310 1ae599a507d778275c5e38a5ebe8cb68 325 Pfam PF01012 Electron transfer flavoprotein domain 5 179 4.3E-46 T 11-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFK25_11310 1ae599a507d778275c5e38a5ebe8cb68 325 PIRSF PIRSF000089 1 323 1.5E-115 T 11-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 AFK25_11310 1ae599a507d778275c5e38a5ebe8cb68 325 ProSitePatterns PS00696 Electron transfer flavoprotein alpha-subunit signature. 262 288 - T 11-10-2018 IPR018206 Electron transfer flavoprotein subunit alpha, conserved site Reactome: R-HSA-611105 AFK25_11310 1ae599a507d778275c5e38a5ebe8cb68 325 SMART SM00893 5 195 1.6E-47 T 11-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFK25_11310 1ae599a507d778275c5e38a5ebe8cb68 325 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 198 281 6.0E-36 T 11-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 AFK25_06820 a03c46211fe4daca651ff9420526b3d4 362 Pfam PF02515 CoA-transferase family III 2 350 7.7E-89 T 11-10-2018 IPR003673 CoA-transferase family III GO:0003824 AFK25_06820 a03c46211fe4daca651ff9420526b3d4 362 Gene3D G3DSA:3.40.50.10540 1 218 7.0E-75 T 11-10-2018 IPR023606 CoA-transferase family III domain superfamily AFK25_06820 a03c46211fe4daca651ff9420526b3d4 362 Gene3D G3DSA:3.30.1540.10 219 302 1.0E-20 T 11-10-2018 AFK25_06820 a03c46211fe4daca651ff9420526b3d4 362 SUPERFAMILY SSF89796 2 356 3.27E-94 T 11-10-2018 IPR023606 CoA-transferase family III domain superfamily AFK25_14090 05aa9a617eb472bd0eaaf4d2bc582a75 74 Hamap MF_01863 UPF0741 protein . 1 74 30.777 T 11-10-2018 IPR020880 Protein of unknown function UPF0741 AFK25_14090 05aa9a617eb472bd0eaaf4d2bc582a75 74 Pfam PF07293 Protein of unknown function (DUF1450) 7 73 2.9E-10 T 11-10-2018 IPR009910 Protein of unknown function DUF1450 AFK25_14090 05aa9a617eb472bd0eaaf4d2bc582a75 74 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 13 74 8.0E-4 T 11-10-2018 AFK25_13910 88c2b8fc4664203870dd83f8f169dd5d 126 Gene3D G3DSA:3.40.50.2300 1 126 5.9E-44 T 11-10-2018 AFK25_13910 88c2b8fc4664203870dd83f8f169dd5d 126 SUPERFAMILY SSF52788 1 126 5.76E-30 T 11-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily AFK25_13910 88c2b8fc4664203870dd83f8f169dd5d 126 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 1 122 1.7E-22 T 11-10-2018 IPR023485 Phosphotyrosine protein phosphatase I AFK25_13910 88c2b8fc4664203870dd83f8f169dd5d 126 SMART SM00226 1 125 2.0E-21 T 11-10-2018 IPR023485 Phosphotyrosine protein phosphatase I AFK25_09975 ef390a7c0fada8a18b7752a4ef1ecd48 448 PIRSF PIRSF006815 3 447 3.9E-194 T 11-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 AFK25_09975 ef390a7c0fada8a18b7752a4ef1ecd48 448 Pfam PF02347 Glycine cleavage system P-protein 3 442 1.0E-163 T 11-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 AFK25_09975 ef390a7c0fada8a18b7752a4ef1ecd48 448 Gene3D G3DSA:3.90.1150.10 73 443 8.7E-171 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_09975 ef390a7c0fada8a18b7752a4ef1ecd48 448 Gene3D G3DSA:3.40.640.10 84 349 8.7E-171 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_09975 ef390a7c0fada8a18b7752a4ef1ecd48 448 Hamap MF_00712 Probable glycine dehydrogenase (decarboxylating) subunit 1 [gcvPA]. 3 446 51.586 T 11-10-2018 IPR023010 Probable glycine dehydrogenase (decarboxylating) subunit 1 GO:0004375|GO:0009116 KEGG: 00260+1.4.4.2 AFK25_09975 ef390a7c0fada8a18b7752a4ef1ecd48 448 SUPERFAMILY SSF53383 3 444 5.65E-128 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_01255 5123336e8708812804738248e47e7ece 506 Gene3D G3DSA:3.40.50.620 195 386 1.3E-76 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_01255 5123336e8708812804738248e47e7ece 506 Gene3D G3DSA:3.40.50.880 1 194 1.1E-57 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_01255 5123336e8708812804738248e47e7ece 506 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 2 189 1.2E-82 T 11-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AFK25_01255 5123336e8708812804738248e47e7ece 506 SUPERFAMILY SSF52317 1 221 1.29E-59 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_01255 5123336e8708812804738248e47e7ece 506 Gene3D G3DSA:3.30.300.10 387 506 6.1E-54 T 11-10-2018 AFK25_01255 5123336e8708812804738248e47e7ece 506 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 197 506 6.2E-162 T 11-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AFK25_01255 5123336e8708812804738248e47e7ece 506 Pfam PF00958 GMP synthase C terminal domain 414 505 8.2E-46 T 11-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AFK25_01255 5123336e8708812804738248e47e7ece 506 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 73 89 1.8E-5 T 11-10-2018 AFK25_01255 5123336e8708812804738248e47e7ece 506 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 2 16 1.8E-5 T 11-10-2018 AFK25_01255 5123336e8708812804738248e47e7ece 506 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 43 57 1.8E-5 T 11-10-2018 AFK25_01255 5123336e8708812804738248e47e7ece 506 Hamap MF_00344 GMP synthase [glutamine-hydrolyzing] [guaA]. 1 506 55.181 T 11-10-2018 IPR022955 GMP synthase GO:0003922|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 AFK25_01255 5123336e8708812804738248e47e7ece 506 PRINTS PR00096 Glutamine amidotransferase superfamily signature 161 174 1.2E-6 T 11-10-2018 AFK25_01255 5123336e8708812804738248e47e7ece 506 PRINTS PR00096 Glutamine amidotransferase superfamily signature 46 55 1.2E-6 T 11-10-2018 AFK25_01255 5123336e8708812804738248e47e7ece 506 PRINTS PR00096 Glutamine amidotransferase superfamily signature 73 84 1.2E-6 T 11-10-2018 AFK25_01255 5123336e8708812804738248e47e7ece 506 SUPERFAMILY SSF54810 386 506 8.24E-53 T 11-10-2018 AFK25_01255 5123336e8708812804738248e47e7ece 506 Pfam PF02540 NAD synthase 208 276 2.6E-5 T 11-10-2018 IPR022310 NAD/GMP synthase AFK25_01255 5123336e8708812804738248e47e7ece 506 Pfam PF00117 Glutamine amidotransferase class-I 3 184 3.4E-44 T 11-10-2018 IPR017926 Glutamine amidotransferase AFK25_01255 5123336e8708812804738248e47e7ece 506 SUPERFAMILY SSF52402 181 399 2.65E-63 T 11-10-2018 AFK25_03520 91710c4230d60884cefcc53f57afc187 285 Gene3D G3DSA:3.40.30.10 28 207 6.7E-27 T 11-10-2018 AFK25_03520 91710c4230d60884cefcc53f57afc187 285 Pfam PF13743 Thioredoxin 26 210 4.6E-73 T 11-10-2018 AFK25_03520 91710c4230d60884cefcc53f57afc187 285 Gene3D G3DSA:1.10.472.60 63 180 6.7E-27 T 11-10-2018 AFK25_03520 91710c4230d60884cefcc53f57afc187 285 SUPERFAMILY SSF52833 23 217 1.55E-28 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_08925 57ab4c5bd48189ca28880b1b9ed3552f 256 PRINTS PR00996 Glutamate methyltransferase family signature 60 72 6.2E-40 T 11-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFK25_08925 57ab4c5bd48189ca28880b1b9ed3552f 256 PRINTS PR00996 Glutamate methyltransferase family signature 129 145 6.2E-40 T 11-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFK25_08925 57ab4c5bd48189ca28880b1b9ed3552f 256 PRINTS PR00996 Glutamate methyltransferase family signature 23 36 6.2E-40 T 11-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFK25_08925 57ab4c5bd48189ca28880b1b9ed3552f 256 PRINTS PR00996 Glutamate methyltransferase family signature 195 209 6.2E-40 T 11-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFK25_08925 57ab4c5bd48189ca28880b1b9ed3552f 256 PRINTS PR00996 Glutamate methyltransferase family signature 214 237 6.2E-40 T 11-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFK25_08925 57ab4c5bd48189ca28880b1b9ed3552f 256 PRINTS PR00996 Glutamate methyltransferase family signature 97 117 6.2E-40 T 11-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFK25_08925 57ab4c5bd48189ca28880b1b9ed3552f 256 Gene3D G3DSA:3.40.50.150 66 256 2.0E-65 T 11-10-2018 AFK25_08925 57ab4c5bd48189ca28880b1b9ed3552f 256 Pfam PF01739 CheR methyltransferase, SAM binding domain 67 240 2.7E-59 T 11-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal AFK25_08925 57ab4c5bd48189ca28880b1b9ed3552f 256 SUPERFAMILY SSF53335 67 254 3.77E-49 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_08925 57ab4c5bd48189ca28880b1b9ed3552f 256 SUPERFAMILY SSF47757 2 66 2.22E-12 T 11-10-2018 AFK25_08925 57ab4c5bd48189ca28880b1b9ed3552f 256 SMART SM00138 1 254 2.4E-103 T 11-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AFK25_08925 57ab4c5bd48189ca28880b1b9ed3552f 256 Pfam PF03705 CheR methyltransferase, all-alpha domain 3 53 1.1E-14 T 11-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal AFK25_05270 a0c2a5b0fa6db8a5cb0aeb736b41db99 239 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 86 99 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05270 a0c2a5b0fa6db8a5cb0aeb736b41db99 239 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 58 234 5.5E-37 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFK25_05270 a0c2a5b0fa6db8a5cb0aeb736b41db99 239 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 205 231 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05270 a0c2a5b0fa6db8a5cb0aeb736b41db99 239 PIRSF PIRSF000770 1 239 3.3E-78 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05270 a0c2a5b0fa6db8a5cb0aeb736b41db99 239 Gene3D G3DSA:1.20.120.1810 23 131 2.8E-25 T 11-10-2018 AFK25_05270 a0c2a5b0fa6db8a5cb0aeb736b41db99 239 SUPERFAMILY SSF88659 143 237 7.66E-22 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFK25_05270 a0c2a5b0fa6db8a5cb0aeb736b41db99 239 Gene3D G3DSA:1.10.10.10 174 239 1.1E-13 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_05270 a0c2a5b0fa6db8a5cb0aeb736b41db99 239 Pfam PF04542 Sigma-70 region 2 62 131 1.9E-18 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_05270 a0c2a5b0fa6db8a5cb0aeb736b41db99 239 Pfam PF04545 Sigma-70, region 4 180 233 5.9E-17 T 11-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFK25_05270 a0c2a5b0fa6db8a5cb0aeb736b41db99 239 SUPERFAMILY SSF88946 25 131 2.88E-35 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_05270 a0c2a5b0fa6db8a5cb0aeb736b41db99 239 PRINTS PR00046 Major sigma-70 factor signature 86 99 1.0E-11 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05270 a0c2a5b0fa6db8a5cb0aeb736b41db99 239 PRINTS PR00046 Major sigma-70 factor signature 184 196 1.0E-11 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05270 a0c2a5b0fa6db8a5cb0aeb736b41db99 239 PRINTS PR00046 Major sigma-70 factor signature 220 231 1.0E-11 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05270 a0c2a5b0fa6db8a5cb0aeb736b41db99 239 PRINTS PR00046 Major sigma-70 factor signature 205 220 1.0E-11 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_05270 a0c2a5b0fa6db8a5cb0aeb736b41db99 239 TIGRFAM TIGR02835 spore_sigmaE: RNA polymerase sigma-E factor 8 239 1.3E-134 T 11-10-2018 IPR014200 RNA polymerase sigma-E type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFK25_10740 3cf8a87310e5bf3d0f79c151edf8f637 254 SUPERFAMILY SSF69572 4 245 4.19E-64 T 11-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 AFK25_10740 3cf8a87310e5bf3d0f79c151edf8f637 254 Gene3D G3DSA:3.40.50.720 1 254 4.5E-83 T 11-10-2018 AFK25_10740 3cf8a87310e5bf3d0f79c151edf8f637 254 Pfam PF00899 ThiF family 6 180 8.1E-40 T 11-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 AFK25_11035 90efd7b60d6ca0bc897b924d24d9bc1e 248 SUPERFAMILY SSF50346 94 150 8.63E-7 T 11-10-2018 IPR011033 PRC-barrel-like superfamily AFK25_11035 90efd7b60d6ca0bc897b924d24d9bc1e 248 SUPERFAMILY SSF50346 2 67 9.61E-9 T 11-10-2018 IPR011033 PRC-barrel-like superfamily AFK25_11035 90efd7b60d6ca0bc897b924d24d9bc1e 248 Pfam PF05239 PRC-barrel domain 93 149 3.2E-6 T 11-10-2018 IPR027275 PRC-barrel domain AFK25_11035 90efd7b60d6ca0bc897b924d24d9bc1e 248 Pfam PF05239 PRC-barrel domain 4 67 6.0E-7 T 11-10-2018 IPR027275 PRC-barrel domain AFK25_00240 61458b37127170ff933f43703b105ae5 292 ProDom PD127708 YABG PROTEASE SPORULATION-SPECIFIC PEPTIDASE U57 BH0058 ORTHOLOG SPORE FAMILY B.SUBTILIS 1 279 4.0E-123 T 11-10-2018 IPR008764 Peptidase U57, YabG AFK25_00240 61458b37127170ff933f43703b105ae5 292 TIGRFAM TIGR02855 spore_yabG: sporulation peptidase YabG 3 285 1.8E-142 T 11-10-2018 IPR008764 Peptidase U57, YabG AFK25_00240 61458b37127170ff933f43703b105ae5 292 PIRSF PIRSF011575 1 289 1.0E-121 T 11-10-2018 IPR008764 Peptidase U57, YabG AFK25_00240 61458b37127170ff933f43703b105ae5 292 Pfam PF05582 YabG peptidase U57 3 284 3.0E-119 T 11-10-2018 IPR008764 Peptidase U57, YabG AFK25_05205 398168e40e7af19613ed9a1fedc2e6ca 488 Gene3D G3DSA:3.40.1390.10 2 96 2.6E-30 T 11-10-2018 AFK25_05205 398168e40e7af19613ed9a1fedc2e6ca 488 Hamap MF_00208 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase [murE]. 1 482 36.96 T 11-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 AFK25_05205 398168e40e7af19613ed9a1fedc2e6ca 488 Pfam PF01225 Mur ligase family, catalytic domain 22 94 3.1E-16 T 11-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AFK25_05205 398168e40e7af19613ed9a1fedc2e6ca 488 SUPERFAMILY SSF63418 2 97 2.49E-28 T 11-10-2018 IPR035911 MurE/MurF, N-terminal AFK25_05205 398168e40e7af19613ed9a1fedc2e6ca 488 Pfam PF02875 Mur ligase family, glutamate ligase domain 332 416 1.5E-26 T 11-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 AFK25_05205 398168e40e7af19613ed9a1fedc2e6ca 488 SUPERFAMILY SSF53244 332 484 1.83E-52 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFK25_05205 398168e40e7af19613ed9a1fedc2e6ca 488 Gene3D G3DSA:3.90.190.20 337 488 1.8E-63 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFK25_05205 398168e40e7af19613ed9a1fedc2e6ca 488 Gene3D G3DSA:3.40.1190.10 97 336 9.6E-92 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFK25_05205 398168e40e7af19613ed9a1fedc2e6ca 488 SUPERFAMILY SSF53623 97 331 1.57E-75 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFK25_05205 398168e40e7af19613ed9a1fedc2e6ca 488 TIGRFAM TIGR01085 murE: UDP-N-acetylmuramyl-tripeptide synthetase 21 482 2.9E-177 T 11-10-2018 IPR005761 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase GO:0005524|GO:0005737|GO:0008360|GO:0016881|GO:0051301 AFK25_05205 398168e40e7af19613ed9a1fedc2e6ca 488 Pfam PF08245 Mur ligase middle domain 106 311 5.9E-56 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 AFK25_04470 0514e32d6d71ee3183bbcf6086657108 468 SUPERFAMILY SSF158472 192 238 8.11E-12 T 11-10-2018 AFK25_04470 0514e32d6d71ee3183bbcf6086657108 468 SMART SM00388 243 310 1.6E-20 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_04470 0514e32d6d71ee3183bbcf6086657108 468 SMART SM00304 190 242 9.8E-15 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_04470 0514e32d6d71ee3183bbcf6086657108 468 SMART SM00387 354 466 2.6E-40 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_04470 0514e32d6d71ee3183bbcf6086657108 468 SUPERFAMILY SSF47384 226 308 7.85E-23 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFK25_04470 0514e32d6d71ee3183bbcf6086657108 468 Gene3D G3DSA:1.10.8.500 189 238 1.6E-11 T 11-10-2018 AFK25_04470 0514e32d6d71ee3183bbcf6086657108 468 SUPERFAMILY SSF55874 300 464 5.37E-49 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_04470 0514e32d6d71ee3183bbcf6086657108 468 Gene3D G3DSA:1.10.287.130 239 310 8.1E-26 T 11-10-2018 AFK25_04470 0514e32d6d71ee3183bbcf6086657108 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 409 419 6.8E-16 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04470 0514e32d6d71ee3183bbcf6086657108 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 426 444 6.8E-16 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04470 0514e32d6d71ee3183bbcf6086657108 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 450 463 6.8E-16 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04470 0514e32d6d71ee3183bbcf6086657108 468 PRINTS PR00344 Bacterial sensor protein C-terminal signature 391 405 6.8E-16 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04470 0514e32d6d71ee3183bbcf6086657108 468 Pfam PF00512 His Kinase A (phospho-acceptor) domain 244 309 4.1E-22 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_04470 0514e32d6d71ee3183bbcf6086657108 468 Pfam PF00672 HAMP domain 192 238 1.3E-13 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_04470 0514e32d6d71ee3183bbcf6086657108 468 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 354 464 3.2E-27 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_04470 0514e32d6d71ee3183bbcf6086657108 468 Gene3D G3DSA:3.30.565.10 314 467 1.4E-49 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_05645 416a8cef435d7cc58753139ded2e6f41 259 Gene3D G3DSA:1.10.10.10 160 259 6.7E-48 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_05645 416a8cef435d7cc58753139ded2e6f41 259 PIRSF PIRSF011572 1 257 2.0E-125 T 11-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 AFK25_05645 416a8cef435d7cc58753139ded2e6f41 259 TIGRFAM TIGR02787 codY_Gpos: GTP-sensing transcriptional pleiotropic repressor CodY 3 253 5.2E-127 T 11-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 AFK25_05645 416a8cef435d7cc58753139ded2e6f41 259 Hamap MF_00621 GTP-sensing transcriptional pleiotropic repressor CodY [codY]. 1 259 152.92 T 11-10-2018 IPR014154 GTP-sensing transcriptional pleiotropic repressor CodY GO:0003677|GO:0003700|GO:0005525|GO:0045892 AFK25_05645 416a8cef435d7cc58753139ded2e6f41 259 Gene3D G3DSA:3.30.450.40 1 159 1.3E-71 T 11-10-2018 IPR029016 GAF-like domain superfamily AFK25_05645 416a8cef435d7cc58753139ded2e6f41 259 SUPERFAMILY SSF46785 167 256 5.86E-43 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_05645 416a8cef435d7cc58753139ded2e6f41 259 Pfam PF06018 CodY GAF-like domain 2 178 2.5E-83 T 11-10-2018 IPR010312 GTP-sensing transcriptional pleiotropic repressor CodY, N-terminal GO:0003677|GO:0005525 AFK25_05645 416a8cef435d7cc58753139ded2e6f41 259 Pfam PF08222 CodY helix-turn-helix domain 197 257 2.0E-38 T 11-10-2018 IPR013198 GTP-sensing helix-turn-helix, CodY, C-terminal AFK25_01430 b813eacfa1525f8b33f0feb49edf9256 449 Gene3D G3DSA:3.40.605.10 10 421 5.4E-180 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFK25_01430 b813eacfa1525f8b33f0feb49edf9256 449 Gene3D G3DSA:3.40.309.10 210 401 5.4E-180 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFK25_01430 b813eacfa1525f8b33f0feb49edf9256 449 Pfam PF00171 Aldehyde dehydrogenase family 5 421 5.1E-94 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFK25_01430 b813eacfa1525f8b33f0feb49edf9256 449 SUPERFAMILY SSF53720 2 437 8.38E-131 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFK25_01430 b813eacfa1525f8b33f0feb49edf9256 449 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 234 245 - T 11-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 AFK25_01430 b813eacfa1525f8b33f0feb49edf9256 449 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 206 213 - T 11-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 AFK25_01430 b813eacfa1525f8b33f0feb49edf9256 449 PIRSF PIRSF036492 1 449 2.4E-187 T 11-10-2018 IPR012394 Aldehyde dehydrogenase NAD(P)-dependent GO:0006081|GO:0055114 AFK25_10235 5b005351e93f195a0c1f28a53bb06f46 84 Pfam PF11116 Protein of unknown function (DUF2624) 2 83 2.3E-31 T 11-10-2018 IPR020277 Protein of unknown function DUF2624 AFK25_10235 5b005351e93f195a0c1f28a53bb06f46 84 ProDom PD060869 YQFT IG BH1387 1 74 2.0E-13 T 11-10-2018 IPR020277 Protein of unknown function DUF2624 AFK25_06170 351dd4c203911301fd8e72391ff4cbe4 133 Pfam PF06094 Gamma-glutamyl cyclotransferase, AIG2-like 6 116 3.6E-19 T 11-10-2018 IPR009288 Gamma-glutamylcyclotransferase, AIG2-like AFK25_06170 351dd4c203911301fd8e72391ff4cbe4 133 Gene3D G3DSA:3.10.490.10 4 125 3.0E-23 T 11-10-2018 AFK25_06170 351dd4c203911301fd8e72391ff4cbe4 133 SUPERFAMILY SSF110857 5 124 1.7E-22 T 11-10-2018 IPR036568 Gamma-glutamyl cyclotransferase-like superfamily AFK25_00395 522024cb0fa15223fc6cc125b05e249b 466 Gene3D G3DSA:3.60.120.10 1 462 4.5E-169 T 11-10-2018 IPR005801 ADC synthase GO:0009058 AFK25_00395 522024cb0fa15223fc6cc125b05e249b 466 PRINTS PR00095 Anthranilate synthase component I signature 307 320 7.9E-21 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFK25_00395 522024cb0fa15223fc6cc125b05e249b 466 PRINTS PR00095 Anthranilate synthase component I signature 387 401 7.9E-21 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFK25_00395 522024cb0fa15223fc6cc125b05e249b 466 PRINTS PR00095 Anthranilate synthase component I signature 402 416 7.9E-21 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFK25_00395 522024cb0fa15223fc6cc125b05e249b 466 PRINTS PR00095 Anthranilate synthase component I signature 293 306 7.9E-21 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFK25_00395 522024cb0fa15223fc6cc125b05e249b 466 TIGRFAM TIGR00564 trpE_most: anthranilate synthase component I 15 453 6.7E-160 T 11-10-2018 IPR005256 Anthranilate synthase component I, PabB-like GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFK25_00395 522024cb0fa15223fc6cc125b05e249b 466 TIGRFAM TIGR00553 pabB: aminodeoxychorismate synthase, component I 97 446 1.9E-99 T 11-10-2018 IPR005802 Para-aminobenzoate synthase, component I GO:0009396 KEGG: 00790+2.6.1.85|MetaCyc: PWY-6543 AFK25_00395 522024cb0fa15223fc6cc125b05e249b 466 Pfam PF04715 Anthranilate synthase component I, N terminal region 14 143 4.5E-34 T 11-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFK25_00395 522024cb0fa15223fc6cc125b05e249b 466 SUPERFAMILY SSF56322 4 452 5.89E-153 T 11-10-2018 IPR005801 ADC synthase GO:0009058 AFK25_00395 522024cb0fa15223fc6cc125b05e249b 466 Pfam PF00425 chorismate binding enzyme 191 445 1.5E-101 T 11-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal AFK25_00395 522024cb0fa15223fc6cc125b05e249b 466 TIGRFAM TIGR01824 PabB-clade2: aminodeoxychorismate synthase, component I 94 449 2.9E-123 T 11-10-2018 IPR010118 Para-aminobenzoate synthase/anthranilate synthase, component I AFK25_04245 3cc6a1a90a2ab2791fe654f1d2ee8996 261 Pfam PF03741 Integral membrane protein TerC family 15 201 3.1E-51 T 11-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 AFK25_04245 3cc6a1a90a2ab2791fe654f1d2ee8996 261 TIGRFAM TIGR03716 R_switched_YkoY: integral membrane protein, YkoY family 12 242 5.2E-92 T 11-10-2018 IPR022493 Integral membrane YkoY AFK25_07245 f14b33aa9085eb6bcd50ac3d41634349 49 ProSitePatterns PS00582 Ribosomal protein L33 signature. 17 36 - T 11-10-2018 IPR018264 Ribosomal protein L33, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_07245 f14b33aa9085eb6bcd50ac3d41634349 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 3 49 1.9E-22 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_07245 f14b33aa9085eb6bcd50ac3d41634349 49 SUPERFAMILY SSF57829 1 49 2.14E-20 T 11-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AFK25_07245 f14b33aa9085eb6bcd50ac3d41634349 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 20.167 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_07245 f14b33aa9085eb6bcd50ac3d41634349 49 Pfam PF00471 Ribosomal protein L33 3 49 9.0E-25 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_07245 f14b33aa9085eb6bcd50ac3d41634349 49 Gene3D G3DSA:2.20.28.120 1 49 2.7E-25 T 11-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_04260 c6d9fe2f9cac55da9f197ccc6fe3e6fd 447 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 74 85 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFK25_04260 c6d9fe2f9cac55da9f197ccc6fe3e6fd 447 Pfam PF02754 Cysteine-rich domain 194 276 8.0E-19 T 11-10-2018 IPR004017 Cysteine-rich domain AFK25_04260 c6d9fe2f9cac55da9f197ccc6fe3e6fd 447 Pfam PF02754 Cysteine-rich domain 324 409 1.6E-16 T 11-10-2018 IPR004017 Cysteine-rich domain AFK25_04260 c6d9fe2f9cac55da9f197ccc6fe3e6fd 447 Pfam PF13183 4Fe-4S dicluster domain 19 88 1.4E-12 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFK25_04260 c6d9fe2f9cac55da9f197ccc6fe3e6fd 447 SUPERFAMILY SSF46548 7 104 6.8E-19 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFK25_04260 c6d9fe2f9cac55da9f197ccc6fe3e6fd 447 PIRSF PIRSF000139 2 439 1.3E-146 T 11-10-2018 AFK25_04260 c6d9fe2f9cac55da9f197ccc6fe3e6fd 447 Gene3D G3DSA:1.10.1060.10 1 109 5.2E-8 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFK25_11825 7017c89b9137fe6a956f8b6f80b29b04 262 SUPERFAMILY SSF89550 3 259 3.14E-31 T 11-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFK25_11825 7017c89b9137fe6a956f8b6f80b29b04 262 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 2 256 3.5E-66 T 11-10-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 AFK25_11825 7017c89b9137fe6a956f8b6f80b29b04 262 Gene3D G3DSA:3.20.20.140 2 262 2.1E-62 T 11-10-2018 AFK25_11825 7017c89b9137fe6a956f8b6f80b29b04 262 Pfam PF02811 PHP domain 3 121 4.9E-13 T 11-10-2018 IPR004013 PHP domain GO:0003824 AFK25_11145 21def7e992e63b0396b6d0fe7f87f781 420 Pfam PF06689 ClpX C4-type zinc finger 12 48 7.5E-20 T 11-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 AFK25_11145 21def7e992e63b0396b6d0fe7f87f781 420 Gene3D G3DSA:1.10.8.60 309 415 2.9E-39 T 11-10-2018 AFK25_11145 21def7e992e63b0396b6d0fe7f87f781 420 SUPERFAMILY SSF52540 59 396 2.33E-81 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_11145 21def7e992e63b0396b6d0fe7f87f781 420 SMART SM00994 10 49 3.9E-23 T 11-10-2018 IPR010603 Zinc finger, ClpX C4-type GO:0008270|GO:0046983 AFK25_11145 21def7e992e63b0396b6d0fe7f87f781 420 SMART SM01086 310 405 2.7E-33 T 11-10-2018 IPR019489 Clp ATPase, C-terminal AFK25_11145 21def7e992e63b0396b6d0fe7f87f781 420 TIGRFAM TIGR00382 clpX: ATP-dependent Clp protease, ATP-binding subunit ClpX 2 405 3.6E-214 T 11-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 AFK25_11145 21def7e992e63b0396b6d0fe7f87f781 420 Gene3D G3DSA:3.40.50.300 53 308 1.4E-110 T 11-10-2018 AFK25_11145 21def7e992e63b0396b6d0fe7f87f781 420 Pfam PF07724 AAA domain (Cdc48 subfamily) 109 304 1.9E-51 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFK25_11145 21def7e992e63b0396b6d0fe7f87f781 420 SMART SM00382 108 269 9.4E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_11145 21def7e992e63b0396b6d0fe7f87f781 420 Pfam PF10431 C-terminal, D2-small domain, of ClpB protein 310 388 1.1E-17 T 11-10-2018 IPR019489 Clp ATPase, C-terminal AFK25_11145 21def7e992e63b0396b6d0fe7f87f781 420 SUPERFAMILY SSF57716 11 46 3.14E-11 T 11-10-2018 AFK25_11145 21def7e992e63b0396b6d0fe7f87f781 420 Gene3D G3DSA:3.30.50.30 3 50 1.8E-21 T 11-10-2018 IPR038366 Zinc finger, ClpX C4-type superfamily AFK25_11145 21def7e992e63b0396b6d0fe7f87f781 420 Hamap MF_00175 ATP-dependent Clp protease ATP-binding subunit ClpX [clpX]. 2 408 54.238 T 11-10-2018 IPR004487 Clp protease, ATP-binding subunit ClpX GO:0005524|GO:0006457|GO:0051082 AFK25_04575 a3dbcde5bdcc82fdaf9a51750a9d493d 67 Pfam PF07872 Protein of unknown function (DUF1659) 4 45 1.5E-13 T 11-10-2018 IPR012454 Protein of unknown function DUF1659 AFK25_05020 539735b81b5cc083d6049d8bc9a625aa 354 TIGRFAM TIGR02866 CoxB: cytochrome c oxidase, subunit II 34 245 2.6E-52 T 11-10-2018 IPR014222 Cytochrome c oxidase, subunit II GO:0016021|GO:0016491 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05020 539735b81b5cc083d6049d8bc9a625aa 354 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 154 234 1.5E-12 T 11-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05020 539735b81b5cc083d6049d8bc9a625aa 354 Gene3D G3DSA:2.60.40.2600 127 354 5.7E-67 T 11-10-2018 AFK25_05020 539735b81b5cc083d6049d8bc9a625aa 354 PRINTS PR01166 Cytochrome c oxidase subunit II signature 99 119 1.3E-8 T 11-10-2018 AFK25_05020 539735b81b5cc083d6049d8bc9a625aa 354 PRINTS PR01166 Cytochrome c oxidase subunit II signature 87 99 1.3E-8 T 11-10-2018 AFK25_05020 539735b81b5cc083d6049d8bc9a625aa 354 PRINTS PR01166 Cytochrome c oxidase subunit II signature 217 234 1.3E-8 T 11-10-2018 AFK25_05020 539735b81b5cc083d6049d8bc9a625aa 354 Gene3D G3DSA:1.10.287.90 28 119 4.1E-25 T 11-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05020 539735b81b5cc083d6049d8bc9a625aa 354 Pfam PF02790 Cytochrome C oxidase subunit II, transmembrane domain 51 110 1.6E-10 T 11-10-2018 IPR011759 Cytochrome C oxidase subunit II, transmembrane domain GO:0016021|GO:0022900 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05020 539735b81b5cc083d6049d8bc9a625aa 354 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 174 228 - T 11-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05020 539735b81b5cc083d6049d8bc9a625aa 354 SUPERFAMILY SSF46626 254 352 2.47E-18 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFK25_05020 539735b81b5cc083d6049d8bc9a625aa 354 Pfam PF00034 Cytochrome c 260 351 2.3E-11 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05020 539735b81b5cc083d6049d8bc9a625aa 354 SUPERFAMILY SSF81464 16 120 1.52E-23 T 11-10-2018 IPR036257 Cytochrome C oxidase subunit II, transmembrane domain superfamily Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_05020 539735b81b5cc083d6049d8bc9a625aa 354 SUPERFAMILY SSF49503 125 280 1.13E-40 T 11-10-2018 IPR008972 Cupredoxin AFK25_00515 6be155c743f171fe9d497da1546ac44a 169 Pfam PF05991 YacP-like NYN domain 4 166 4.8E-56 T 11-10-2018 IPR010298 Protein of unknown function DUF901 AFK25_13855 57b440a6a044e6a4c7f339efb3bffac9 169 TIGRFAM TIGR01144 ATP_synt_b: ATP synthase F0, B subunit 19 165 4.0E-45 T 11-10-2018 IPR005864 ATP synthase, F0 complex, subunit b, bacterial GO:0015078|GO:0015986|GO:0045263 AFK25_13855 57b440a6a044e6a4c7f339efb3bffac9 169 Pfam PF00430 ATP synthase B/B' CF(0) 16 146 1.2E-39 T 11-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 AFK25_13855 57b440a6a044e6a4c7f339efb3bffac9 169 SUPERFAMILY SSF81573 72 130 1.22E-8 T 11-10-2018 IPR028987 F-type ATP synthase subunit B-like, membrane domain superfamily AFK25_13855 57b440a6a044e6a4c7f339efb3bffac9 169 Hamap MF_01398 ATP synthase subunit b [atpF]. 10 147 13.849 T 11-10-2018 IPR002146 ATP synthase, F0 complex, subunit b/b', bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 AFK25_03230 eee9b802071aa856f4c771327b7d24bc 240 Pfam PF02361 Cobalt transport protein 2 200 1.1E-20 T 11-10-2018 IPR003339 ABC/ECF transporter, transmembrane component AFK25_00390 89320bbbd224d0e327bb3faac9cd7c38 308 Gene3D G3DSA:3.40.50.1100 7 300 7.2E-127 T 11-10-2018 AFK25_00390 89320bbbd224d0e327bb3faac9cd7c38 308 SUPERFAMILY SSF53686 4 305 1.83E-106 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFK25_00390 89320bbbd224d0e327bb3faac9cd7c38 308 Gene3D G3DSA:3.40.50.1100 46 144 7.2E-127 T 11-10-2018 AFK25_00390 89320bbbd224d0e327bb3faac9cd7c38 308 TIGRFAM TIGR01136 cysKM: cysteine synthase 8 304 2.3E-136 T 11-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 AFK25_00390 89320bbbd224d0e327bb3faac9cd7c38 308 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 9 292 1.0E-72 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFK25_00390 89320bbbd224d0e327bb3faac9cd7c38 308 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 304 2.6E-144 T 11-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 AFK25_00390 89320bbbd224d0e327bb3faac9cd7c38 308 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 34 52 - T 11-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 AFK25_03370 9248f0e52fe6d9c97a586c2d0fb89051 408 Gene3D G3DSA:3.60.70.12 5 194 2.0E-70 T 11-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFK25_03370 9248f0e52fe6d9c97a586c2d0fb89051 408 SUPERFAMILY SSF56266 18 404 1.26E-140 T 11-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFK25_03370 9248f0e52fe6d9c97a586c2d0fb89051 408 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 35 408 7.0E-170 T 11-10-2018 AFK25_03370 9248f0e52fe6d9c97a586c2d0fb89051 408 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 408 149.501 T 11-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFK25_03370 9248f0e52fe6d9c97a586c2d0fb89051 408 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 13 408 9.7E-159 T 11-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFK25_03370 9248f0e52fe6d9c97a586c2d0fb89051 408 Gene3D G3DSA:3.10.20.340 280 408 1.2E-47 T 11-10-2018 AFK25_03370 9248f0e52fe6d9c97a586c2d0fb89051 408 Pfam PF01960 ArgJ family 24 408 6.2E-149 T 11-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AFK25_03370 9248f0e52fe6d9c97a586c2d0fb89051 408 Gene3D G3DSA:3.30.2330.10 195 279 2.6E-33 T 11-10-2018 AFK25_00725 7daf4c47f7f7eb87b15e0b26d32f1de9 37 ProDom PD002101 RIBOSOMAL L36 RIBONUCLEOPROTEIN 50S CHLOROPLAST PLASTID B SUBUNIT DIRECT SEQUENCING 10 37 1.0E-8 T 11-10-2018 AFK25_00725 7daf4c47f7f7eb87b15e0b26d32f1de9 37 ProSitePatterns PS00828 Ribosomal protein L36 signature. 11 36 - T 11-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00725 7daf4c47f7f7eb87b15e0b26d32f1de9 37 TIGRFAM TIGR01022 rpmJ_bact: ribosomal protein bL36 1 37 9.2E-24 T 11-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00725 7daf4c47f7f7eb87b15e0b26d32f1de9 37 SUPERFAMILY SSF57840 1 37 6.41E-17 T 11-10-2018 IPR035977 Ribosomal protein L36 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00725 7daf4c47f7f7eb87b15e0b26d32f1de9 37 Pfam PF00444 Ribosomal protein L36 1 37 5.7E-19 T 11-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00725 7daf4c47f7f7eb87b15e0b26d32f1de9 37 Hamap MF_00251 50S ribosomal protein L36 [rpmJ]. 1 37 17.778 T 11-10-2018 IPR000473 Ribosomal protein L36 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_06125 6f98b35153049b4acd99814e75b8bed4 707 SUPERFAMILY SSF53098 279 706 5.06E-56 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_06125 6f98b35153049b4acd99814e75b8bed4 707 SMART SM00950 423 694 5.3E-18 T 11-10-2018 IPR003165 Piwi domain GO:0003676 AFK25_06125 6f98b35153049b4acd99814e75b8bed4 707 Gene3D G3DSA:3.30.420.10 485 666 8.8E-40 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFK25_06125 6f98b35153049b4acd99814e75b8bed4 707 Pfam PF02171 Piwi domain 424 686 3.3E-21 T 11-10-2018 IPR003165 Piwi domain GO:0003676 AFK25_05680 fe93bbc0e1a9f080479e0934469bc1c2 437 SUPERFAMILY SSF52540 92 360 4.19E-98 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_05680 fe93bbc0e1a9f080479e0934469bc1c2 437 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 145 354 3.2E-75 T 11-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFK25_05680 fe93bbc0e1a9f080479e0934469bc1c2 437 TIGRFAM TIGR03497 FliI_clade2: flagellar protein export ATPase FliI 20 433 7.0E-208 T 11-10-2018 IPR022425 Flagellar export ATPase FliI, clade 2 GO:0016887|GO:0044780|GO:0071973 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFK25_05680 fe93bbc0e1a9f080479e0934469bc1c2 437 SMART SM00382 157 338 7.3E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_05680 fe93bbc0e1a9f080479e0934469bc1c2 437 Gene3D G3DSA:3.40.50.12240 10 436 2.3E-156 T 11-10-2018 AFK25_05680 fe93bbc0e1a9f080479e0934469bc1c2 437 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 22 88 5.1E-10 T 11-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFK25_05680 fe93bbc0e1a9f080479e0934469bc1c2 437 TIGRFAM TIGR01026 fliI_yscN: ATPase, FliI/YscN family 12 433 2.0E-198 T 11-10-2018 IPR005714 ATPase, type III secretion system, FliI/YscN GO:0005737|GO:0009058|GO:0016887|GO:0030254|GO:0030257 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFK25_05680 fe93bbc0e1a9f080479e0934469bc1c2 437 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 345 354 - T 11-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFK25_06980 4cbeeebfc040863fb7e3574f4ab7eaa3 133 SUPERFAMILY SSF111038 2 133 2.49E-48 T 11-10-2018 IPR035917 YjbQ-like superfamily AFK25_06980 4cbeeebfc040863fb7e3574f4ab7eaa3 133 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 5 131 9.3E-55 T 11-10-2018 IPR001602 Uncharacterised protein family UPF0047 AFK25_06980 4cbeeebfc040863fb7e3574f4ab7eaa3 133 Pfam PF01894 Uncharacterised protein family UPF0047 17 130 1.9E-40 T 11-10-2018 IPR001602 Uncharacterised protein family UPF0047 AFK25_06980 4cbeeebfc040863fb7e3574f4ab7eaa3 133 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 95 113 - T 11-10-2018 IPR001602 Uncharacterised protein family UPF0047 AFK25_06980 4cbeeebfc040863fb7e3574f4ab7eaa3 133 Gene3D G3DSA:2.60.120.460 1 133 7.0E-55 T 11-10-2018 IPR035917 YjbQ-like superfamily AFK25_06980 4cbeeebfc040863fb7e3574f4ab7eaa3 133 PIRSF PIRSF004681 1 133 3.0E-39 T 11-10-2018 IPR001602 Uncharacterised protein family UPF0047 AFK25_12645 02fd01b35e21be8c8a14071f815c4b47 256 Pfam PF13344 Haloacid dehalogenase-like hydrolase 8 107 2.6E-29 T 11-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA AFK25_12645 02fd01b35e21be8c8a14071f815c4b47 256 SUPERFAMILY SSF56784 4 253 4.2E-78 T 11-10-2018 IPR036412 HAD-like superfamily AFK25_12645 02fd01b35e21be8c8a14071f815c4b47 256 PIRSF PIRSF000915 107 256 6.1E-37 T 11-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA AFK25_12645 02fd01b35e21be8c8a14071f815c4b47 256 PIRSF PIRSF000915 1 115 1.6E-28 T 11-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA AFK25_12645 02fd01b35e21be8c8a14071f815c4b47 256 TIGRFAM TIGR01457 HAD-SF-IIA-hyp2: HAD hydrolase, TIGR01457 family 4 252 2.2E-125 T 11-10-2018 IPR006354 HAD-superfamily hydrolase, subfamily IIA, hypothetical 1 AFK25_12645 02fd01b35e21be8c8a14071f815c4b47 256 Pfam PF13242 HAD-hyrolase-like 179 251 9.3E-25 T 11-10-2018 AFK25_12645 02fd01b35e21be8c8a14071f815c4b47 256 Gene3D G3DSA:3.40.50.1000 84 179 2.5E-91 T 11-10-2018 IPR023214 HAD superfamily AFK25_12645 02fd01b35e21be8c8a14071f815c4b47 256 Gene3D G3DSA:3.40.50.1000 6 242 2.5E-91 T 11-10-2018 IPR023214 HAD superfamily AFK25_12645 02fd01b35e21be8c8a14071f815c4b47 256 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 8 228 9.8E-48 T 11-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA AFK25_05160 95e7149cd95c18b6397c71ebfa358018 250 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 96 116 - T 11-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 AFK25_05160 95e7149cd95c18b6397c71ebfa358018 250 SUPERFAMILY SSF52096 2 249 6.26E-64 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFK25_05160 95e7149cd95c18b6397c71ebfa358018 250 Pfam PF00378 Enoyl-CoA hydratase/isomerase 3 249 2.2E-41 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFK25_05160 95e7149cd95c18b6397c71ebfa358018 250 Gene3D G3DSA:3.90.226.10 1 250 1.6E-64 T 11-10-2018 AFK25_13590 6a37ec1fdbfb030ceb7745446f8a1f8c 510 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 356 493 1.4E-24 T 11-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain AFK25_13590 6a37ec1fdbfb030ceb7745446f8a1f8c 510 PIRSF PIRSF038958 1 510 5.9E-86 T 11-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type AFK25_13590 6a37ec1fdbfb030ceb7745446f8a1f8c 510 Pfam PF01943 Polysaccharide biosynthesis protein 6 303 1.1E-34 T 11-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 AFK25_05385 eb74a6027b261d0e214a00776d8aaf94 570 Gene3D G3DSA:1.10.8.50 168 237 1.6E-22 T 11-10-2018 AFK25_05385 eb74a6027b261d0e214a00776d8aaf94 570 Pfam PF05670 Domain of unknown function (DUF814) 453 537 9.9E-31 T 11-10-2018 IPR008532 Domain of unknown function DUF814 AFK25_05385 eb74a6027b261d0e214a00776d8aaf94 570 Gene3D G3DSA:3.40.970.40 239 289 2.0E-15 T 11-10-2018 AFK25_05385 eb74a6027b261d0e214a00776d8aaf94 570 Gene3D G3DSA:2.30.310.10 1 167 1.2E-69 T 11-10-2018 AFK25_05385 eb74a6027b261d0e214a00776d8aaf94 570 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 4 444 3.8E-174 T 11-10-2018 AFK25_05835 19c4d50191092f201b49369d9039538b 183 Gene3D G3DSA:1.10.132.20 10 180 4.3E-73 T 11-10-2018 AFK25_05835 19c4d50191092f201b49369d9039538b 183 TIGRFAM TIGR00496 frr: ribosome recycling factor 8 183 7.3E-79 T 11-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 AFK25_05835 19c4d50191092f201b49369d9039538b 183 Gene3D G3DSA:3.30.1360.40 29 103 4.3E-73 T 11-10-2018 AFK25_05835 19c4d50191092f201b49369d9039538b 183 Pfam PF01765 Ribosome recycling factor 18 181 9.1E-68 T 11-10-2018 IPR023584 Ribosome recycling factor domain Reactome: R-HSA-5419276 AFK25_05835 19c4d50191092f201b49369d9039538b 183 Hamap MF_00040 Ribosome-recycling factor [frr]. 1 183 29.073 T 11-10-2018 IPR002661 Ribosome recycling factor GO:0006412 Reactome: R-HSA-5419276 AFK25_05835 19c4d50191092f201b49369d9039538b 183 SUPERFAMILY SSF55194 3 182 5.76E-74 T 11-10-2018 IPR036191 RRF superfamily Reactome: R-HSA-5419276 AFK25_10775 a7ecb1e7adbb254ca61636eb94a8c9f3 170 TIGRFAM TIGR01090 apt: adenine phosphoribosyltransferase 3 169 2.2E-72 T 11-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 AFK25_10775 a7ecb1e7adbb254ca61636eb94a8c9f3 170 Pfam PF00156 Phosphoribosyl transferase domain 45 148 3.5E-15 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFK25_10775 a7ecb1e7adbb254ca61636eb94a8c9f3 170 Gene3D G3DSA:3.40.50.2020 1 170 7.7E-63 T 11-10-2018 AFK25_10775 a7ecb1e7adbb254ca61636eb94a8c9f3 170 SUPERFAMILY SSF53271 2 164 5.82E-52 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like AFK25_10775 a7ecb1e7adbb254ca61636eb94a8c9f3 170 Hamap MF_00004 Adenine phosphoribosyltransferase [apt]. 3 170 38.876 T 11-10-2018 IPR005764 Adenine phosphoribosyl transferase GO:0003999|GO:0005737|GO:0006168 KEGG: 00230+2.4.2.7|MetaCyc: PWY-6605|MetaCyc: PWY-6610|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-6798695|Reactome: R-HSA-74217 AFK25_06845 cb1e0fe5b0a21adc68ee08c37188512a 415 Pfam PF13167 GTP-binding GTPase N-terminal 23 110 4.7E-35 T 11-10-2018 IPR025121 GTPase HflX, N-terminal AFK25_06845 cb1e0fe5b0a21adc68ee08c37188512a 415 Gene3D G3DSA:3.40.50.300 197 362 2.6E-35 T 11-10-2018 AFK25_06845 cb1e0fe5b0a21adc68ee08c37188512a 415 Pfam PF01926 50S ribosome-binding GTPase 197 316 7.8E-20 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_06845 cb1e0fe5b0a21adc68ee08c37188512a 415 SUPERFAMILY SSF52540 196 365 6.66E-41 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_06845 cb1e0fe5b0a21adc68ee08c37188512a 415 TIGRFAM TIGR03156 GTP_HflX: GTP-binding protein HflX 5 353 1.7E-146 T 11-10-2018 IPR016496 GTPase HflX GO:0005525 AFK25_06845 cb1e0fe5b0a21adc68ee08c37188512a 415 Pfam PF16360 GTP-binding GTPase Middle Region 112 190 2.0E-31 T 11-10-2018 IPR032305 GTP-binding protein, middle domain AFK25_06845 cb1e0fe5b0a21adc68ee08c37188512a 415 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 198 218 3.2E-9 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_06845 cb1e0fe5b0a21adc68ee08c37188512a 415 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 265 283 3.2E-9 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_06845 cb1e0fe5b0a21adc68ee08c37188512a 415 Hamap MF_00900 GTPase HflX [hflX]. 25 383 48.091 T 11-10-2018 IPR016496 GTPase HflX GO:0005525 AFK25_06845 cb1e0fe5b0a21adc68ee08c37188512a 415 PIRSF PIRSF006809 1 409 5.5E-152 T 11-10-2018 IPR016496 GTPase HflX GO:0005525 AFK25_06845 cb1e0fe5b0a21adc68ee08c37188512a 415 Gene3D G3DSA:3.40.50.11060 16 136 1.6E-42 T 11-10-2018 AFK25_14525 fad68f9c539283f53390249fa2c535dd 261 Gene3D G3DSA:3.10.450.660 48 252 2.8E-68 T 11-10-2018 AFK25_14525 fad68f9c539283f53390249fa2c535dd 261 Gene3D G3DSA:3.30.310.160 70 181 2.8E-68 T 11-10-2018 AFK25_14525 fad68f9c539283f53390249fa2c535dd 261 Pfam PF09648 YycH protein 40 248 4.7E-62 T 11-10-2018 IPR018604 Regulatory protein YycH-like GO:0016021 AFK25_09505 c648bf1bd90e4f23c1d3b62b538d7e55 229 SMART SM00100 4 121 2.0E-9 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain AFK25_09505 c648bf1bd90e4f23c1d3b62b538d7e55 229 SUPERFAMILY SSF51206 19 134 3.54E-26 T 11-10-2018 IPR018490 Cyclic nucleotide-binding-like AFK25_09505 c648bf1bd90e4f23c1d3b62b538d7e55 229 Pfam PF13545 Crp-like helix-turn-helix domain 142 214 4.2E-17 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFK25_09505 c648bf1bd90e4f23c1d3b62b538d7e55 229 SUPERFAMILY SSF46785 139 223 6.27E-23 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_09505 c648bf1bd90e4f23c1d3b62b538d7e55 229 SMART SM00419 160 208 2.4E-11 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFK25_09505 c648bf1bd90e4f23c1d3b62b538d7e55 229 Gene3D G3DSA:2.60.120.10 2 136 3.5E-29 T 11-10-2018 IPR014710 RmlC-like jelly roll fold AFK25_09505 c648bf1bd90e4f23c1d3b62b538d7e55 229 Pfam PF00027 Cyclic nucleotide-binding domain 22 105 1.8E-16 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain AFK25_09505 c648bf1bd90e4f23c1d3b62b538d7e55 229 Gene3D G3DSA:1.10.10.10 137 223 6.8E-28 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_10530 c3cf44479dde654b5fbb0747a2a66ad3 237 PIRSF PIRSF000770 2 237 2.2E-86 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_10530 c3cf44479dde654b5fbb0747a2a66ad3 237 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 50 225 8.3E-32 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFK25_10530 c3cf44479dde654b5fbb0747a2a66ad3 237 Gene3D G3DSA:1.20.120.1810 20 125 4.5E-24 T 11-10-2018 AFK25_10530 c3cf44479dde654b5fbb0747a2a66ad3 237 PRINTS PR00046 Major sigma-70 factor signature 78 91 3.0E-14 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_10530 c3cf44479dde654b5fbb0747a2a66ad3 237 PRINTS PR00046 Major sigma-70 factor signature 176 188 3.0E-14 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_10530 c3cf44479dde654b5fbb0747a2a66ad3 237 PRINTS PR00046 Major sigma-70 factor signature 212 223 3.0E-14 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_10530 c3cf44479dde654b5fbb0747a2a66ad3 237 PRINTS PR00046 Major sigma-70 factor signature 197 212 3.0E-14 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_10530 c3cf44479dde654b5fbb0747a2a66ad3 237 Gene3D G3DSA:1.10.10.10 166 232 7.9E-16 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_10530 c3cf44479dde654b5fbb0747a2a66ad3 237 SUPERFAMILY SSF88946 8 122 2.49E-35 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_10530 c3cf44479dde654b5fbb0747a2a66ad3 237 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 197 223 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_10530 c3cf44479dde654b5fbb0747a2a66ad3 237 Pfam PF04542 Sigma-70 region 2 54 123 9.1E-17 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_10530 c3cf44479dde654b5fbb0747a2a66ad3 237 Pfam PF04545 Sigma-70, region 4 173 225 2.0E-17 T 11-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFK25_10530 c3cf44479dde654b5fbb0747a2a66ad3 237 SUPERFAMILY SSF88659 138 226 5.61E-21 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFK25_10530 c3cf44479dde654b5fbb0747a2a66ad3 237 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 78 91 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_10530 c3cf44479dde654b5fbb0747a2a66ad3 237 TIGRFAM TIGR02846 spore_sigmaK: RNA polymerase sigma-K factor 5 227 5.6E-112 T 11-10-2018 IPR014209 RNA polymerase sigma-K type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFK25_05770 c8e197b9fcbf76499d4545949e4163fa 289 Gene3D G3DSA:3.40.50.300 22 263 3.1E-61 T 11-10-2018 AFK25_05770 c8e197b9fcbf76499d4545949e4163fa 289 SUPERFAMILY SSF52540 23 281 9.56E-52 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_05770 c8e197b9fcbf76499d4545949e4163fa 289 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 23 260 4.6E-20 T 11-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 AFK25_05770 c8e197b9fcbf76499d4545949e4163fa 289 PIRSF PIRSF003092 2 289 7.9E-80 T 11-10-2018 IPR025501 ATP binding protein MinD AFK25_01500 e49aebb9d1a4b1dd70d5264a2bfe49df 308 Gene3D G3DSA:2.60.200.40 134 288 5.5E-41 T 11-10-2018 AFK25_01500 e49aebb9d1a4b1dd70d5264a2bfe49df 308 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 1 298 4.6E-112 T 11-10-2018 IPR005218 Diacylglycerol/lipid kinase AFK25_01500 e49aebb9d1a4b1dd70d5264a2bfe49df 308 SUPERFAMILY SSF111331 1 299 5.07E-86 T 11-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily AFK25_01500 e49aebb9d1a4b1dd70d5264a2bfe49df 308 SMART SM00046 3 130 4.6E-8 T 11-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 AFK25_01500 e49aebb9d1a4b1dd70d5264a2bfe49df 308 Pfam PF00781 Diacylglycerol kinase catalytic domain 4 126 1.7E-37 T 11-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 AFK25_01500 e49aebb9d1a4b1dd70d5264a2bfe49df 308 Gene3D G3DSA:3.40.50.10330 1 133 7.8E-49 T 11-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 AFK25_01665 611a6da3795e6131ba81bed4ee58467a 708 Pfam PF17159 Membrane-associated sensor domain 34 263 3.1E-59 T 11-10-2018 IPR033425 Membrane-associated sensor domain MASE3 AFK25_01665 611a6da3795e6131ba81bed4ee58467a 708 Gene3D G3DSA:3.30.70.270 279 454 2.0E-57 T 11-10-2018 AFK25_01665 611a6da3795e6131ba81bed4ee58467a 708 SMART SM00267 274 441 1.4E-58 T 11-10-2018 IPR000160 GGDEF domain AFK25_01665 611a6da3795e6131ba81bed4ee58467a 708 SUPERFAMILY SSF141868 457 700 3.92E-83 T 11-10-2018 IPR035919 EAL domain superfamily AFK25_01665 611a6da3795e6131ba81bed4ee58467a 708 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 281 440 8.6E-40 T 11-10-2018 IPR000160 GGDEF domain AFK25_01665 611a6da3795e6131ba81bed4ee58467a 708 SMART SM00052 451 697 3.4E-103 T 11-10-2018 IPR001633 EAL domain AFK25_01665 611a6da3795e6131ba81bed4ee58467a 708 Pfam PF00990 Diguanylate cyclase, GGDEF domain 285 437 1.2E-45 T 11-10-2018 IPR000160 GGDEF domain AFK25_01665 611a6da3795e6131ba81bed4ee58467a 708 Pfam PF00563 EAL domain 457 692 4.0E-71 T 11-10-2018 IPR001633 EAL domain AFK25_01665 611a6da3795e6131ba81bed4ee58467a 708 SUPERFAMILY SSF55073 290 443 1.41E-46 T 11-10-2018 IPR029787 Nucleotide cyclase AFK25_01665 611a6da3795e6131ba81bed4ee58467a 708 Gene3D G3DSA:3.20.20.450 455 704 4.5E-91 T 11-10-2018 IPR035919 EAL domain superfamily AFK25_13040 232f89d633d93a473becdfd68a23188f 311 Gene3D G3DSA:3.40.50.300 132 311 4.1E-77 T 11-10-2018 AFK25_13040 232f89d633d93a473becdfd68a23188f 311 Gene3D G3DSA:3.40.1390.20 1 131 3.8E-43 T 11-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily AFK25_13040 232f89d633d93a473becdfd68a23188f 311 SUPERFAMILY SSF75138 1 131 4.71E-40 T 11-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily AFK25_13040 232f89d633d93a473becdfd68a23188f 311 TIGRFAM TIGR00679 hpr-ser: HPr(Ser) kinase/phosphatase 6 302 5.0E-119 T 11-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 AFK25_13040 232f89d633d93a473becdfd68a23188f 311 Pfam PF07475 HPr Serine kinase C-terminal domain 130 298 3.3E-78 T 11-10-2018 IPR011104 HPr kinase/phosphorylase, C-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 AFK25_13040 232f89d633d93a473becdfd68a23188f 311 SUPERFAMILY SSF53795 132 297 5.19E-43 T 11-10-2018 AFK25_13040 232f89d633d93a473becdfd68a23188f 311 Hamap MF_01249 HPr kinase/phosphorylase [hprK]. 3 306 42.28 T 11-10-2018 IPR003755 HPr(Ser) kinase/phosphorylase GO:0000155|GO:0000160|GO:0005524|GO:0006109 AFK25_13040 232f89d633d93a473becdfd68a23188f 311 Pfam PF02603 HPr Serine kinase N terminus 4 127 6.6E-39 T 11-10-2018 IPR011126 HPr(Ser) kinase/phosphorylase, N-terminal GO:0000155|GO:0000160|GO:0004672|GO:0005524|GO:0006109 AFK25_09355 ceab7461840d7a2307127dc9426a2f63 146 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 45 57 1.7E-24 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFK25_09355 ceab7461840d7a2307127dc9426a2f63 146 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 85 100 1.7E-24 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFK25_09355 ceab7461840d7a2307127dc9426a2f63 146 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 113 128 1.7E-24 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFK25_09355 ceab7461840d7a2307127dc9426a2f63 146 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 100 112 1.7E-24 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFK25_09355 ceab7461840d7a2307127dc9426a2f63 146 PRINTS PR00153 Cyclophilin peptidyl-prolyl cis-trans isomerase signature 19 34 1.7E-24 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFK25_09355 ceab7461840d7a2307127dc9426a2f63 146 PIRSF PIRSF001467 4 146 1.4E-40 T 11-10-2018 IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomerase GO:0003755 AFK25_09355 ceab7461840d7a2307127dc9426a2f63 146 ProSitePatterns PS00170 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. 40 57 - T 11-10-2018 IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site GO:0003755|GO:0006457 AFK25_09355 ceab7461840d7a2307127dc9426a2f63 146 SUPERFAMILY SSF50891 11 138 2.92E-48 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily AFK25_09355 ceab7461840d7a2307127dc9426a2f63 146 Gene3D G3DSA:2.40.100.10 1 146 1.3E-63 T 11-10-2018 IPR029000 Cyclophilin-like domain superfamily AFK25_09355 ceab7461840d7a2307127dc9426a2f63 146 Pfam PF00160 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD 9 138 3.3E-43 T 11-10-2018 IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain GO:0000413|GO:0003755 AFK25_00005 9223d746d1d281ad5dc29b52b3a3d252 447 Gene3D G3DSA:3.40.50.300 94 276 3.3E-56 T 11-10-2018 AFK25_00005 9223d746d1d281ad5dc29b52b3a3d252 447 Hamap MF_00377 Chromosomal replication initiator protein DnaA [dnaA]. 5 447 35.399 T 11-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 AFK25_00005 9223d746d1d281ad5dc29b52b3a3d252 447 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 209 223 7.8E-54 T 11-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like AFK25_00005 9223d746d1d281ad5dc29b52b3a3d252 447 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 177 191 7.8E-54 T 11-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like AFK25_00005 9223d746d1d281ad5dc29b52b3a3d252 447 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 243 270 7.8E-54 T 11-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like AFK25_00005 9223d746d1d281ad5dc29b52b3a3d252 447 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 406 425 7.8E-54 T 11-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like AFK25_00005 9223d746d1d281ad5dc29b52b3a3d252 447 PRINTS PR00051 Bacterial chromosomal replication initiator (DNAA) signature 145 165 7.8E-54 T 11-10-2018 IPR020591 Chromosomal replication control, initiator DnaA-like AFK25_00005 9223d746d1d281ad5dc29b52b3a3d252 447 Pfam PF11638 DnaA N-terminal domain 6 66 1.9E-17 T 11-10-2018 IPR024633 DnaA N-terminal domain AFK25_00005 9223d746d1d281ad5dc29b52b3a3d252 447 Pfam PF00308 Bacterial dnaA protein 112 328 2.1E-107 T 11-10-2018 IPR013317 Chromosomal replication initiator protein DnaA AFK25_00005 9223d746d1d281ad5dc29b52b3a3d252 447 SUPERFAMILY SSF48295 343 447 2.54E-37 T 11-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 AFK25_00005 9223d746d1d281ad5dc29b52b3a3d252 447 Gene3D G3DSA:1.10.1750.10 347 447 2.0E-35 T 11-10-2018 IPR010921 Trp repressor/replication initiator GO:0043565 AFK25_00005 9223d746d1d281ad5dc29b52b3a3d252 447 SMART SM00760 356 425 7.5E-43 T 11-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 AFK25_00005 9223d746d1d281ad5dc29b52b3a3d252 447 SMART SM00382 144 272 3.7E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_00005 9223d746d1d281ad5dc29b52b3a3d252 447 Gene3D G3DSA:1.10.8.60 278 346 2.5E-30 T 11-10-2018 AFK25_00005 9223d746d1d281ad5dc29b52b3a3d252 447 SUPERFAMILY SSF52540 112 324 8.07E-48 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_00005 9223d746d1d281ad5dc29b52b3a3d252 447 ProSitePatterns PS01008 DnaA protein signature. 406 425 - T 11-10-2018 IPR018312 Chromosomal replication control, initiator DnaA, conserved site GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 AFK25_00005 9223d746d1d281ad5dc29b52b3a3d252 447 Pfam PF08299 Bacterial dnaA protein helix-turn-helix 357 425 4.9E-31 T 11-10-2018 IPR013159 Chromosomal replication initiator, DnaA C-terminal GO:0005524|GO:0006270|GO:0006275|GO:0043565 AFK25_00005 9223d746d1d281ad5dc29b52b3a3d252 447 TIGRFAM TIGR00362 DnaA: chromosomal replication initiator protein DnaA 8 446 4.5E-190 T 11-10-2018 IPR001957 Chromosomal replication control, initiator DnaA GO:0003677|GO:0003688|GO:0005524|GO:0006270|GO:0006275 AFK25_00005 9223d746d1d281ad5dc29b52b3a3d252 447 Gene3D G3DSA:3.30.300.180 1 82 7.5E-31 T 11-10-2018 IPR038454 DnaA, N-terminal domain superfamily AFK25_11765 37075ba353fd99fc8cf4f158a8c45698 262 SUPERFAMILY SSF52540 2 240 5.9E-53 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_11765 37075ba353fd99fc8cf4f158a8c45698 262 Pfam PF00005 ABC transporter 18 168 1.0E-26 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_11765 37075ba353fd99fc8cf4f158a8c45698 262 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_11765 37075ba353fd99fc8cf4f158a8c45698 262 Gene3D G3DSA:3.40.50.300 1 242 4.8E-56 T 11-10-2018 AFK25_11765 37075ba353fd99fc8cf4f158a8c45698 262 SMART SM00382 27 235 1.3E-6 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_11845 ff119ea554cc7a0edde8b9a7764cc470 419 SUPERFAMILY SSF52374 2 323 3.06E-109 T 11-10-2018 AFK25_11845 ff119ea554cc7a0edde8b9a7764cc470 419 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 39 49 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_11845 ff119ea554cc7a0edde8b9a7764cc470 419 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 418 1.0E-144 T 11-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFK25_11845 ff119ea554cc7a0edde8b9a7764cc470 419 Gene3D G3DSA:3.40.50.620 1 222 6.1E-93 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_11845 ff119ea554cc7a0edde8b9a7764cc470 419 SMART SM00363 353 415 9.5E-7 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_11845 ff119ea554cc7a0edde8b9a7764cc470 419 Gene3D G3DSA:3.10.290.10 326 419 2.0E-37 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFK25_11845 ff119ea554cc7a0edde8b9a7764cc470 419 Pfam PF01479 S4 domain 354 396 2.9E-8 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_11845 ff119ea554cc7a0edde8b9a7764cc470 419 Pfam PF00579 tRNA synthetases class I (W and Y) 28 323 4.9E-91 T 11-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_11845 ff119ea554cc7a0edde8b9a7764cc470 419 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 161 176 2.2E-33 T 11-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFK25_11845 ff119ea554cc7a0edde8b9a7764cc470 419 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 43 65 2.2E-33 T 11-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFK25_11845 ff119ea554cc7a0edde8b9a7764cc470 419 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 216 228 2.2E-33 T 11-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFK25_11845 ff119ea554cc7a0edde8b9a7764cc470 419 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 182 204 2.2E-33 T 11-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AFK25_11845 ff119ea554cc7a0edde8b9a7764cc470 419 Gene3D G3DSA:1.10.240.10 223 325 3.9E-41 T 11-10-2018 AFK25_11845 ff119ea554cc7a0edde8b9a7764cc470 419 SUPERFAMILY SSF55174 321 418 2.36E-25 T 11-10-2018 AFK25_11845 ff119ea554cc7a0edde8b9a7764cc470 419 Hamap MF_02006 Tyrosine--tRNA ligase [tyrS]. 1 418 47.141 T 11-10-2018 IPR024107 Tyrosine-tRNA ligase, bacterial-type, type 1 GO:0004831 KEGG: 00970+6.1.1.1 AFK25_14590 01dc8a37b505f42718097a3658622776 95 Pfam PF01250 Ribosomal protein S6 3 92 2.6E-32 T 11-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_14590 01dc8a37b505f42718097a3658622776 95 Hamap MF_00360 30S ribosomal protein S6 [rpsF]. 1 95 24.352 T 11-10-2018 IPR020814 Ribosomal protein S6, plastid/chloroplast GO:0003735|GO:0005840|GO:0006412|GO:0019843 AFK25_14590 01dc8a37b505f42718097a3658622776 95 TIGRFAM TIGR00166 S6: ribosomal protein bS6 1 94 2.8E-33 T 11-10-2018 IPR000529 Ribosomal protein S6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_14590 01dc8a37b505f42718097a3658622776 95 Gene3D G3DSA:3.30.70.60 1 95 1.8E-36 T 11-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 AFK25_14590 01dc8a37b505f42718097a3658622776 95 SUPERFAMILY SSF54995 1 95 1.7E-36 T 11-10-2018 IPR035980 Ribosomal protein S6 superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_08195 ca1dae11e79ceffd10565716f4177046 409 SUPERFAMILY SSF103473 10 399 1.31E-25 T 11-10-2018 IPR036259 MFS transporter superfamily AFK25_08195 ca1dae11e79ceffd10565716f4177046 409 Gene3D G3DSA:1.20.1250.20 9 396 1.9E-17 T 11-10-2018 AFK25_08195 ca1dae11e79ceffd10565716f4177046 409 Pfam PF07690 Major Facilitator Superfamily 258 395 7.5E-10 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFK25_03020 e9e958aeb2bcaf0156fa83f3b97f78e2 172 PIRSF PIRSF011560 1 168 6.3E-53 T 11-10-2018 IPR010461 Competence protein ComK GO:0030420 AFK25_03020 e9e958aeb2bcaf0156fa83f3b97f78e2 172 Pfam PF06338 ComK protein 7 153 5.4E-53 T 11-10-2018 IPR010461 Competence protein ComK GO:0030420 AFK25_09685 707fa91b835cedf78e45b81617c534fa 495 Gene3D G3DSA:3.30.360.10 178 490 1.4E-129 T 11-10-2018 AFK25_09685 707fa91b835cedf78e45b81617c534fa 495 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 145 158 1.1E-48 T 11-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFK25_09685 707fa91b835cedf78e45b81617c534fa 495 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 221 238 1.1E-48 T 11-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFK25_09685 707fa91b835cedf78e45b81617c534fa 495 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 239 255 1.1E-48 T 11-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFK25_09685 707fa91b835cedf78e45b81617c534fa 495 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 169 197 1.1E-48 T 11-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFK25_09685 707fa91b835cedf78e45b81617c534fa 495 PRINTS PR00079 Glucose-6-phosphate dehydrogenase signature 330 356 1.1E-48 T 11-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFK25_09685 707fa91b835cedf78e45b81617c534fa 495 Pfam PF02781 Glucose-6-phosphate dehydrogenase, C-terminal domain 192 488 4.6E-120 T 11-10-2018 IPR022675 Glucose-6-phosphate dehydrogenase, C-terminal GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFK25_09685 707fa91b835cedf78e45b81617c534fa 495 Gene3D G3DSA:3.40.50.720 4 177 9.4E-65 T 11-10-2018 AFK25_09685 707fa91b835cedf78e45b81617c534fa 495 SUPERFAMILY SSF51735 6 187 1.08E-62 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_09685 707fa91b835cedf78e45b81617c534fa 495 SUPERFAMILY SSF55347 184 489 2.03E-119 T 11-10-2018 AFK25_09685 707fa91b835cedf78e45b81617c534fa 495 Pfam PF00479 Glucose-6-phosphate dehydrogenase, NAD binding domain 11 189 3.8E-66 T 11-10-2018 IPR022674 Glucose-6-phosphate dehydrogenase, NAD-binding GO:0004345|GO:0006006|GO:0050661|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFK25_09685 707fa91b835cedf78e45b81617c534fa 495 TIGRFAM TIGR00871 zwf: glucose-6-phosphate dehydrogenase 7 490 1.1E-206 T 11-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFK25_09685 707fa91b835cedf78e45b81617c534fa 495 Hamap MF_00966 Glucose-6-phosphate 1-dehydrogenase [zwf]. 7 490 88.712 T 11-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFK25_09685 707fa91b835cedf78e45b81617c534fa 495 ProSitePatterns PS00069 Glucose-6-phosphate dehydrogenase active site. 179 185 - T 11-10-2018 IPR019796 Glucose-6-phosphate dehydrogenase, active site GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFK25_09685 707fa91b835cedf78e45b81617c534fa 495 PIRSF PIRSF000110 2 492 1.3E-196 T 11-10-2018 IPR001282 Glucose-6-phosphate dehydrogenase GO:0004345|GO:0006006|GO:0055114 KEGG: 00030+1.1.1.49|KEGG: 00480+1.1.1.49|MetaCyc: PWY-7268 AFK25_02660 0dad05c3b777c2b8d219346f097699d9 535 Gene3D G3DSA:1.20.1250.20 263 432 4.1E-28 T 11-10-2018 AFK25_02660 0dad05c3b777c2b8d219346f097699d9 535 Gene3D G3DSA:1.20.1720.10 21 211 1.6E-50 T 11-10-2018 AFK25_02660 0dad05c3b777c2b8d219346f097699d9 535 Pfam PF07690 Major Facilitator Superfamily 26 417 2.6E-56 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFK25_02660 0dad05c3b777c2b8d219346f097699d9 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 144 168 3.8E-12 T 11-10-2018 AFK25_02660 0dad05c3b777c2b8d219346f097699d9 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 309 333 3.8E-12 T 11-10-2018 AFK25_02660 0dad05c3b777c2b8d219346f097699d9 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 24 48 3.8E-12 T 11-10-2018 AFK25_02660 0dad05c3b777c2b8d219346f097699d9 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 114 134 3.8E-12 T 11-10-2018 AFK25_02660 0dad05c3b777c2b8d219346f097699d9 535 PRINTS PR01036 Tetracycline resistance protein TetB signature 365 385 3.8E-12 T 11-10-2018 AFK25_02660 0dad05c3b777c2b8d219346f097699d9 535 ProSitePatterns PS00216 Sugar transport proteins signature 1. 74 90 - T 11-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFK25_02660 0dad05c3b777c2b8d219346f097699d9 535 SUPERFAMILY SSF103473 17 524 6.93E-78 T 11-10-2018 IPR036259 MFS transporter superfamily AFK25_02660 0dad05c3b777c2b8d219346f097699d9 535 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 21 487 5.8E-87 T 11-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFK25_09720 5331b2f9a1ec570fe80115d050d82ca5 167 SUPERFAMILY SSF141523 24 149 4.05E-34 T 11-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFK25_09720 5331b2f9a1ec570fe80115d050d82ca5 167 Gene3D G3DSA:2.40.440.10 11 164 7.6E-43 T 11-10-2018 IPR038063 L,D-transpeptidase catalytic domain-like AFK25_09720 5331b2f9a1ec570fe80115d050d82ca5 167 Pfam PF03734 L,D-transpeptidase catalytic domain 27 149 4.0E-23 T 11-10-2018 IPR005490 L,D-transpeptidase catalytic domain GO:0016740 AFK25_10110 fe4688f295e55251d0781a1f8d97e8fa 316 Gene3D G3DSA:3.40.50.720 2 147 1.1E-58 T 11-10-2018 AFK25_10110 fe4688f295e55251d0781a1f8d97e8fa 316 SUPERFAMILY SSF51735 4 145 1.78E-57 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_10110 fe4688f295e55251d0781a1f8d97e8fa 316 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 175 181 - T 11-10-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 AFK25_10110 fe4688f295e55251d0781a1f8d97e8fa 316 Hamap MF_00488 L-lactate dehydrogenase [ldh]. 5 314 49.102 T 11-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 AFK25_10110 fe4688f295e55251d0781a1f8d97e8fa 316 PRINTS PR00086 L-lactate dehydrogenase signature 143 161 5.9E-51 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFK25_10110 fe4688f295e55251d0781a1f8d97e8fa 316 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 5.9E-51 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFK25_10110 fe4688f295e55251d0781a1f8d97e8fa 316 PRINTS PR00086 L-lactate dehydrogenase signature 119 139 5.9E-51 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFK25_10110 fe4688f295e55251d0781a1f8d97e8fa 316 PRINTS PR00086 L-lactate dehydrogenase signature 173 186 5.9E-51 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFK25_10110 fe4688f295e55251d0781a1f8d97e8fa 316 PRINTS PR00086 L-lactate dehydrogenase signature 32 56 5.9E-51 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFK25_10110 fe4688f295e55251d0781a1f8d97e8fa 316 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 145 8.2E-50 T 11-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 AFK25_10110 fe4688f295e55251d0781a1f8d97e8fa 316 PIRSF PIRSF000102 2 316 8.6E-118 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFK25_10110 fe4688f295e55251d0781a1f8d97e8fa 316 Gene3D G3DSA:3.90.110.10 148 315 4.1E-65 T 11-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 AFK25_10110 fe4688f295e55251d0781a1f8d97e8fa 316 SUPERFAMILY SSF56327 146 313 6.7E-61 T 11-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 AFK25_10110 fe4688f295e55251d0781a1f8d97e8fa 316 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 148 312 7.0E-40 T 11-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 AFK25_10110 fe4688f295e55251d0781a1f8d97e8fa 316 TIGRFAM TIGR01771 L-LDH-NAD: L-lactate dehydrogenase 10 308 2.5E-137 T 11-10-2018 IPR011304 L-lactate dehydrogenase GO:0004459|GO:0005737|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 AFK25_01785 dfbf120486b6e16a1250cde9ef9b082a 349 Pfam PF01699 Sodium/calcium exchanger protein 29 178 5.7E-19 T 11-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 AFK25_01785 dfbf120486b6e16a1250cde9ef9b082a 349 Pfam PF01699 Sodium/calcium exchanger protein 204 341 4.8E-18 T 11-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 AFK25_01785 dfbf120486b6e16a1250cde9ef9b082a 349 Gene3D G3DSA:1.20.1420.30 57 340 6.1E-24 T 11-10-2018 AFK25_01785 dfbf120486b6e16a1250cde9ef9b082a 349 TIGRFAM TIGR00378 cax: calcium/proton exchanger 10 347 8.3E-146 T 11-10-2018 IPR004798 Calcium/proton exchanger CAX GO:0006816|GO:0015369 AFK25_01785 dfbf120486b6e16a1250cde9ef9b082a 349 TIGRFAM TIGR00846 caca2: calcium/proton exchanger 3 346 3.9E-119 T 11-10-2018 IPR004713 Calcium/proton exchanger GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFK25_01785 dfbf120486b6e16a1250cde9ef9b082a 349 Gene3D G3DSA:1.20.58.1130 34 236 6.1E-24 T 11-10-2018 AFK25_01225 75a12bc9185cc4af365809401dfc2139 211 SUPERFAMILY SSF51735 84 207 5.61E-31 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_01225 75a12bc9185cc4af365809401dfc2139 211 Pfam PF02629 CoA binding domain 83 178 1.5E-32 T 11-10-2018 IPR003781 CoA-binding GO:0048037 AFK25_01225 75a12bc9185cc4af365809401dfc2139 211 Hamap MF_01131 Redox-sensing transcriptional repressor Rex [rex]. 3 209 39.077 T 11-10-2018 IPR022876 Redox-sensing transcriptional repressor Rex GO:0005737|GO:0045892|GO:0051775 AFK25_01225 75a12bc9185cc4af365809401dfc2139 211 Gene3D G3DSA:3.40.50.720 83 210 1.1E-47 T 11-10-2018 AFK25_01225 75a12bc9185cc4af365809401dfc2139 211 Pfam PF06971 Putative DNA-binding protein N-terminus 7 55 6.3E-20 T 11-10-2018 IPR009718 Rex DNA-binding, C-terminal domain GO:0005737|GO:0045892|GO:0051775 AFK25_01225 75a12bc9185cc4af365809401dfc2139 211 SUPERFAMILY SSF46785 9 80 2.29E-22 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_01225 75a12bc9185cc4af365809401dfc2139 211 SMART SM00881 81 180 2.4E-24 T 11-10-2018 IPR003781 CoA-binding GO:0048037 AFK25_01225 75a12bc9185cc4af365809401dfc2139 211 Gene3D G3DSA:1.10.10.10 1 82 1.9E-31 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_04930 be12d7c22bf2a020436f22cc95c14008 89 Hamap MF_01041 UPF0223 protein . 1 89 25.309 T 11-10-2018 IPR007920 Protein of unknown function UPF0223 AFK25_04930 be12d7c22bf2a020436f22cc95c14008 89 PIRSF PIRSF037260 1 89 5.3E-38 T 11-10-2018 IPR007920 Protein of unknown function UPF0223 AFK25_04930 be12d7c22bf2a020436f22cc95c14008 89 ProDom PD062738 UPF0223 FAMILY UNCHARACTERISED CYTOSOLIC SUPERFAMILY YKTA LMO1058/LIN1050 INOSITOL MW0980 M6_SPY0948 1 81 3.0E-26 T 11-10-2018 IPR007920 Protein of unknown function UPF0223 AFK25_04930 be12d7c22bf2a020436f22cc95c14008 89 Gene3D G3DSA:1.10.220.80 12 89 1.7E-30 T 11-10-2018 IPR023324 BH2638-like superfamily AFK25_04930 be12d7c22bf2a020436f22cc95c14008 89 SUPERFAMILY SSF158504 5 83 4.18E-34 T 11-10-2018 IPR023324 BH2638-like superfamily AFK25_04930 be12d7c22bf2a020436f22cc95c14008 89 Pfam PF05256 Uncharacterised protein family (UPF0223) 2 85 2.7E-38 T 11-10-2018 IPR007920 Protein of unknown function UPF0223 AFK25_02880 a035ca9cde29d5da0a8ce2e560e81c0d 315 SUPERFAMILY SSF53800 3 308 2.62E-95 T 11-10-2018 AFK25_02880 a035ca9cde29d5da0a8ce2e560e81c0d 315 Pfam PF00762 Ferrochelatase 7 307 1.1E-87 T 11-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 AFK25_02880 a035ca9cde29d5da0a8ce2e560e81c0d 315 TIGRFAM TIGR00109 hemH: ferrochelatase 2 308 8.9E-103 T 11-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 AFK25_02880 a035ca9cde29d5da0a8ce2e560e81c0d 315 ProSitePatterns PS00534 Ferrochelatase signature. 178 196 - T 11-10-2018 IPR019772 Ferrochelatase, active site GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 AFK25_02880 a035ca9cde29d5da0a8ce2e560e81c0d 315 Hamap MF_00323 Ferrochelatase [hemH]. 4 308 33.461 T 11-10-2018 IPR001015 Ferrochelatase GO:0004325|GO:0006783 KEGG: 00860+4.99.1.1|Reactome: R-HSA-189451 AFK25_02880 a035ca9cde29d5da0a8ce2e560e81c0d 315 Gene3D G3DSA:3.40.50.1400 8 304 2.1E-111 T 11-10-2018 AFK25_02880 a035ca9cde29d5da0a8ce2e560e81c0d 315 Gene3D G3DSA:3.40.50.1400 148 289 2.1E-111 T 11-10-2018 AFK25_07285 19f3fa22658f61dcbd651cd25ed792a0 477 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 92 107 - T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_07285 19f3fa22658f61dcbd651cd25ed792a0 477 PRINTS PR00175 Sodium/alanine symporter signature 182 200 1.3E-56 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_07285 19f3fa22658f61dcbd651cd25ed792a0 477 PRINTS PR00175 Sodium/alanine symporter signature 210 229 1.3E-56 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_07285 19f3fa22658f61dcbd651cd25ed792a0 477 PRINTS PR00175 Sodium/alanine symporter signature 92 114 1.3E-56 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_07285 19f3fa22658f61dcbd651cd25ed792a0 477 PRINTS PR00175 Sodium/alanine symporter signature 301 319 1.3E-56 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_07285 19f3fa22658f61dcbd651cd25ed792a0 477 PRINTS PR00175 Sodium/alanine symporter signature 406 426 1.3E-56 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_07285 19f3fa22658f61dcbd651cd25ed792a0 477 PRINTS PR00175 Sodium/alanine symporter signature 346 368 1.3E-56 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_07285 19f3fa22658f61dcbd651cd25ed792a0 477 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 437 2.0E-153 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_07285 19f3fa22658f61dcbd651cd25ed792a0 477 Pfam PF01235 Sodium:alanine symporter family 57 449 7.1E-155 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_04185 5763565a29d51b47ac697ff61ec0ff5b 469 SUPERFAMILY SSF48557 8 464 6.75E-152 T 11-10-2018 IPR008948 L-Aspartase-like GO:0003824 AFK25_04185 5763565a29d51b47ac697ff61ec0ff5b 469 Pfam PF00206 Lyase 15 344 2.5E-112 T 11-10-2018 IPR022761 Fumarate lyase, N-terminal AFK25_04185 5763565a29d51b47ac697ff61ec0ff5b 469 PRINTS PR00145 Argininosuccinate lyase family signature 177 197 7.3E-6 T 11-10-2018 AFK25_04185 5763565a29d51b47ac697ff61ec0ff5b 469 PRINTS PR00145 Argininosuccinate lyase family signature 319 335 7.3E-6 T 11-10-2018 AFK25_04185 5763565a29d51b47ac697ff61ec0ff5b 469 Gene3D G3DSA:1.20.200.10 142 409 1.2E-114 T 11-10-2018 AFK25_04185 5763565a29d51b47ac697ff61ec0ff5b 469 TIGRFAM TIGR00839 aspA: aspartate ammonia-lyase 8 469 5.3E-230 T 11-10-2018 IPR004708 Aspartate ammonia-lyase GO:0006531|GO:0008797 KEGG: 00250+4.3.1.1 AFK25_04185 5763565a29d51b47ac697ff61ec0ff5b 469 Gene3D G3DSA:1.10.40.30 410 461 4.6E-21 T 11-10-2018 AFK25_04185 5763565a29d51b47ac697ff61ec0ff5b 469 PRINTS PR00149 Fumarate lyase superfamily signature 137 155 8.1E-33 T 11-10-2018 IPR000362 Fumarate lyase family AFK25_04185 5763565a29d51b47ac697ff61ec0ff5b 469 PRINTS PR00149 Fumarate lyase superfamily signature 182 200 8.1E-33 T 11-10-2018 IPR000362 Fumarate lyase family AFK25_04185 5763565a29d51b47ac697ff61ec0ff5b 469 PRINTS PR00149 Fumarate lyase superfamily signature 273 300 8.1E-33 T 11-10-2018 IPR000362 Fumarate lyase family AFK25_04185 5763565a29d51b47ac697ff61ec0ff5b 469 PRINTS PR00149 Fumarate lyase superfamily signature 319 335 8.1E-33 T 11-10-2018 IPR000362 Fumarate lyase family AFK25_04185 5763565a29d51b47ac697ff61ec0ff5b 469 Pfam PF10415 Fumarase C C-terminus 411 462 3.7E-21 T 11-10-2018 IPR018951 Fumarase C, C-terminal GO:0006099|GO:0016829 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AFK25_04185 5763565a29d51b47ac697ff61ec0ff5b 469 ProSitePatterns PS00163 Fumarate lyases signature. 319 328 - T 11-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 AFK25_04185 5763565a29d51b47ac697ff61ec0ff5b 469 Gene3D G3DSA:1.10.275.10 8 141 1.1E-60 T 11-10-2018 IPR024083 Fumarase/histidase, N-terminal AFK25_02350 3151970d6056115cefe71a41af582df6 180 Pfam PF00589 Phage integrase family 17 167 1.5E-21 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFK25_02350 3151970d6056115cefe71a41af582df6 180 SUPERFAMILY SSF56349 6 176 2.21E-35 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFK25_02350 3151970d6056115cefe71a41af582df6 180 Gene3D G3DSA:1.10.443.10 7 180 1.1E-29 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFK25_07395 c49e0a4b337c99778efec9fcb2e1da4b 138 ProSitePatterns PS00552 MerR-type HTH domain signature. 5 27 - T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_07395 c49e0a4b337c99778efec9fcb2e1da4b 138 Gene3D G3DSA:1.10.1660.10 1 127 4.4E-36 T 11-10-2018 AFK25_07395 c49e0a4b337c99778efec9fcb2e1da4b 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 3 14 3.2E-15 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_07395 c49e0a4b337c99778efec9fcb2e1da4b 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 14 27 3.2E-15 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_07395 c49e0a4b337c99778efec9fcb2e1da4b 138 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 38 58 3.2E-15 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_07395 c49e0a4b337c99778efec9fcb2e1da4b 138 SUPERFAMILY SSF46955 2 128 5.86E-37 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily AFK25_07395 c49e0a4b337c99778efec9fcb2e1da4b 138 SMART SM00422 2 71 4.3E-33 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_07395 c49e0a4b337c99778efec9fcb2e1da4b 138 TIGRFAM TIGR02051 MerR: Hg(II)-responsive transcriptional regulator 3 128 8.0E-50 T 11-10-2018 IPR011794 Hg(II)-responsive transcriptional regulator GO:0003677|GO:0006355|GO:0045340|GO:0046689 AFK25_07395 c49e0a4b337c99778efec9fcb2e1da4b 138 Pfam PF13411 MerR HTH family regulatory protein 2 68 2.4E-21 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_03815 73320fba8d50a194e6f4afde306aae12 417 SUPERFAMILY SSF51126 57 259 4.71E-6 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor AFK25_03815 73320fba8d50a194e6f4afde306aae12 417 Gene3D G3DSA:2.160.20.110 26 250 2.3E-49 T 11-10-2018 AFK25_14365 5aeb3e25e8dfc1bc0c57e1677e2d9473 526 SUPERFAMILY SSF55874 395 513 4.32E-17 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_14365 5aeb3e25e8dfc1bc0c57e1677e2d9473 526 Gene3D G3DSA:3.30.565.10 377 520 3.3E-22 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_14365 5aeb3e25e8dfc1bc0c57e1677e2d9473 526 SMART SM00387 417 515 9.0E-4 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_14365 5aeb3e25e8dfc1bc0c57e1677e2d9473 526 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 420 514 3.4E-8 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_05370 db86aeffc52d2e9ed728c5b1ee0205c1 237 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 6 229 1.5E-60 T 11-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFK25_05370 db86aeffc52d2e9ed728c5b1ee0205c1 237 Gene3D G3DSA:3.20.20.70 1 236 1.0E-82 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_05370 db86aeffc52d2e9ed728c5b1ee0205c1 237 Hamap MF_01200_B Orotidine 5'-phosphate decarboxylase [pyrF]. 2 234 39.449 T 11-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFK25_05370 db86aeffc52d2e9ed728c5b1ee0205c1 237 SUPERFAMILY SSF51366 3 233 1.44E-69 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFK25_05370 db86aeffc52d2e9ed728c5b1ee0205c1 237 ProSitePatterns PS00156 Orotidine 5'-phosphate decarboxylase active site. 56 69 - T 11-10-2018 IPR018089 Orotidine 5'-phosphate decarboxylase, active site GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFK25_05370 db86aeffc52d2e9ed728c5b1ee0205c1 237 SMART SM00934 4 229 1.4E-85 T 11-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFK25_05370 db86aeffc52d2e9ed728c5b1ee0205c1 237 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 4 228 3.6E-44 T 11-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFK25_08805 3ebc27209f3459f7f96e6ef0d67f3afc 135 SMART SM00851 14 107 2.1E-28 T 11-10-2018 IPR011607 Methylglyoxal synthase-like domain AFK25_08805 3ebc27209f3459f7f96e6ef0d67f3afc 135 Gene3D G3DSA:3.40.50.1380 1 133 2.7E-58 T 11-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AFK25_08805 3ebc27209f3459f7f96e6ef0d67f3afc 135 Hamap MF_00549 Methylglyoxal synthase [mgsA]. 1 120 34.626 T 11-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 AFK25_08805 3ebc27209f3459f7f96e6ef0d67f3afc 135 Pfam PF02142 MGS-like domain 14 107 1.7E-21 T 11-10-2018 IPR011607 Methylglyoxal synthase-like domain AFK25_08805 3ebc27209f3459f7f96e6ef0d67f3afc 135 PIRSF PIRSF006614 1 135 2.8E-64 T 11-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 AFK25_08805 3ebc27209f3459f7f96e6ef0d67f3afc 135 TIGRFAM TIGR00160 MGSA: methylglyoxal synthase 2 121 2.5E-61 T 11-10-2018 IPR004363 Methylglyoxal synthase GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 AFK25_08805 3ebc27209f3459f7f96e6ef0d67f3afc 135 ProSitePatterns PS01335 Methylglyoxal synthase active site. 54 62 - T 11-10-2018 IPR018148 Methylglyoxal synthase, active site GO:0008929|GO:0019242 KEGG: 00640+4.2.3.3 AFK25_08805 3ebc27209f3459f7f96e6ef0d67f3afc 135 SUPERFAMILY SSF52335 2 131 5.1E-55 T 11-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AFK25_07915 62e5023ca66c1ba176b50dc5aa8e1207 164 Pfam PF00255 Glutathione peroxidase 3 109 1.6E-46 T 11-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 AFK25_07915 62e5023ca66c1ba176b50dc5aa8e1207 164 ProSitePatterns PS00460 Glutathione peroxidases active site. 23 38 - T 11-10-2018 IPR029759 Glutathione peroxidase active site Reactome: R-HSA-3299685 AFK25_07915 62e5023ca66c1ba176b50dc5aa8e1207 164 PRINTS PR01011 Glutathione peroxidase family signature 122 131 7.1E-22 T 11-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 AFK25_07915 62e5023ca66c1ba176b50dc5aa8e1207 164 PRINTS PR01011 Glutathione peroxidase family signature 21 38 7.1E-22 T 11-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 AFK25_07915 62e5023ca66c1ba176b50dc5aa8e1207 164 PRINTS PR01011 Glutathione peroxidase family signature 56 72 7.1E-22 T 11-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 AFK25_07915 62e5023ca66c1ba176b50dc5aa8e1207 164 ProSitePatterns PS00763 Glutathione peroxidases signature 2. 59 66 - T 11-10-2018 IPR029760 Glutathione peroxidase conserved site Reactome: R-HSA-3299685 AFK25_07915 62e5023ca66c1ba176b50dc5aa8e1207 164 Gene3D G3DSA:3.40.30.10 1 163 3.6E-78 T 11-10-2018 AFK25_07915 62e5023ca66c1ba176b50dc5aa8e1207 164 PIRSF PIRSF000303 1 161 1.2E-72 T 11-10-2018 IPR000889 Glutathione peroxidase GO:0004602|GO:0006979|GO:0055114 Reactome: R-HSA-3299685 AFK25_07915 62e5023ca66c1ba176b50dc5aa8e1207 164 SUPERFAMILY SSF52833 1 158 7.59E-69 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_09055 daee76868e90d5fac90f0b48823b014b 222 Pfam PF13500 AAA domain 2 209 8.0E-47 T 11-10-2018 AFK25_09055 daee76868e90d5fac90f0b48823b014b 222 Gene3D G3DSA:3.40.50.300 2 215 7.7E-65 T 11-10-2018 AFK25_09055 daee76868e90d5fac90f0b48823b014b 222 SUPERFAMILY SSF52540 1 211 1.13E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_09055 daee76868e90d5fac90f0b48823b014b 222 TIGRFAM TIGR00347 bioD: dethiobiotin synthase 5 174 5.2E-49 T 11-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 AFK25_09055 daee76868e90d5fac90f0b48823b014b 222 PIRSF PIRSF006755 1 218 2.5E-72 T 11-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 AFK25_09055 daee76868e90d5fac90f0b48823b014b 222 Hamap MF_00336 ATP-dependent dethiobiotin synthetase BioD [bioD]. 1 211 30.209 T 11-10-2018 IPR004472 Dethiobiotin synthase BioD GO:0000287|GO:0004141|GO:0005524|GO:0009102 KEGG: 00780+6.3.3.3|MetaCyc: PWY-7380 AFK25_08285 5fd0d0e5117a9bbda81384d28f637a8b 541 SUPERFAMILY SSF52518 357 531 1.47E-60 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold AFK25_08285 5fd0d0e5117a9bbda81384d28f637a8b 541 Gene3D G3DSA:3.40.50.1220 183 355 6.2E-47 T 11-10-2018 AFK25_08285 5fd0d0e5117a9bbda81384d28f637a8b 541 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 375 520 5.5E-45 T 11-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFK25_08285 5fd0d0e5117a9bbda81384d28f637a8b 541 SUPERFAMILY SSF52467 153 344 1.9E-47 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFK25_08285 5fd0d0e5117a9bbda81384d28f637a8b 541 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 410 429 - T 11-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 AFK25_08285 5fd0d0e5117a9bbda81384d28f637a8b 541 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 2 168 5.9E-58 T 11-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AFK25_08285 5fd0d0e5117a9bbda81384d28f637a8b 541 Gene3D G3DSA:3.40.50.970 1 179 1.9E-66 T 11-10-2018 AFK25_08285 5fd0d0e5117a9bbda81384d28f637a8b 541 SUPERFAMILY SSF52518 2 182 1.29E-56 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold AFK25_08285 5fd0d0e5117a9bbda81384d28f637a8b 541 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 187 321 4.6E-35 T 11-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AFK25_08285 5fd0d0e5117a9bbda81384d28f637a8b 541 Gene3D G3DSA:3.40.50.970 356 528 7.5E-60 T 11-10-2018 AFK25_03495 34bc174a21f7652256729792b134f594 502 Hamap MF_01916 Cardiolipin synthase. 33 502 43.917 T 11-10-2018 IPR030874 Cardiolipin synthase, Firmicutes-type GO:0008808|GO:0032049 AFK25_03495 34bc174a21f7652256729792b134f594 502 SUPERFAMILY SSF56024 92 332 4.12E-53 T 11-10-2018 AFK25_03495 34bc174a21f7652256729792b134f594 502 Pfam PF13091 PLD-like domain 344 468 6.3E-28 T 11-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFK25_03495 34bc174a21f7652256729792b134f594 502 Pfam PF13091 PLD-like domain 155 297 1.2E-11 T 11-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFK25_03495 34bc174a21f7652256729792b134f594 502 Pfam PF13396 Phospholipase_D-nuclease N-terminal 39 81 6.0E-8 T 11-10-2018 IPR027379 Cardiolipin synthase N-terminal AFK25_03495 34bc174a21f7652256729792b134f594 502 TIGRFAM TIGR04265 bac_cardiolipin: cardiolipin synthase 28 502 1.0E-190 T 11-10-2018 IPR022924 Cardiolipin synthase GO:0008808|GO:0016780|GO:0032049 AFK25_03495 34bc174a21f7652256729792b134f594 502 Gene3D G3DSA:3.30.870.10 332 473 1.7E-28 T 11-10-2018 AFK25_03495 34bc174a21f7652256729792b134f594 502 SUPERFAMILY SSF56024 289 489 6.73E-52 T 11-10-2018 AFK25_03495 34bc174a21f7652256729792b134f594 502 Gene3D G3DSA:3.30.870.10 130 320 2.5E-49 T 11-10-2018 AFK25_03495 34bc174a21f7652256729792b134f594 502 SMART SM00155 237 264 1.6E-5 T 11-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AFK25_03495 34bc174a21f7652256729792b134f594 502 SMART SM00155 415 442 3.1E-8 T 11-10-2018 IPR001736 Phospholipase D/Transphosphatidylase GO:0003824 Reactome: R-HSA-1483148 AFK25_05360 b81e23f928d465ee3485735cc660753c 254 Gene3D G3DSA:3.40.50.80 100 212 9.6E-27 T 11-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFK25_05360 b81e23f928d465ee3485735cc660753c 254 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 2 254 39.135 T 11-10-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit AFK25_05360 b81e23f928d465ee3485735cc660753c 254 PIRSF PIRSF006816 1 254 3.7E-71 T 11-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 AFK25_05360 b81e23f928d465ee3485735cc660753c 254 PRINTS PR00409 Phthalate dioxygenase reductase family signature 186 194 1.7E-5 T 11-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFK25_05360 b81e23f928d465ee3485735cc660753c 254 PRINTS PR00409 Phthalate dioxygenase reductase family signature 109 128 1.7E-5 T 11-10-2018 IPR000951 Phthalate dioxygenase reductase GO:0016491 AFK25_05360 b81e23f928d465ee3485735cc660753c 254 Gene3D G3DSA:2.40.30.10 1 95 3.0E-28 T 11-10-2018 AFK25_05360 b81e23f928d465ee3485735cc660753c 254 SUPERFAMILY SSF63380 4 97 1.7E-23 T 11-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFK25_05360 b81e23f928d465ee3485735cc660753c 254 Pfam PF00175 Oxidoreductase NAD-binding domain 110 199 6.3E-6 T 11-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AFK25_05360 b81e23f928d465ee3485735cc660753c 254 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 213 252 1.6E-16 T 11-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain AFK25_05360 b81e23f928d465ee3485735cc660753c 254 SUPERFAMILY SSF52343 92 253 1.7E-32 T 11-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AFK25_05360 b81e23f928d465ee3485735cc660753c 254 Gene3D G3DSA:2.10.240.10 213 254 7.3E-18 T 11-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily AFK25_08430 f98be184e1822e5ab55c88ea9e427616 458 Pfam PF00512 His Kinase A (phospho-acceptor) domain 236 300 9.6E-19 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_08430 f98be184e1822e5ab55c88ea9e427616 458 SUPERFAMILY SSF47384 220 301 8.63E-20 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFK25_08430 f98be184e1822e5ab55c88ea9e427616 458 Gene3D G3DSA:1.10.287.130 241 302 6.3E-17 T 11-10-2018 AFK25_08430 f98be184e1822e5ab55c88ea9e427616 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 401 411 3.0E-20 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_08430 f98be184e1822e5ab55c88ea9e427616 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 442 455 3.0E-20 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_08430 f98be184e1822e5ab55c88ea9e427616 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 418 436 3.0E-20 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_08430 f98be184e1822e5ab55c88ea9e427616 458 PRINTS PR00344 Bacterial sensor protein C-terminal signature 383 397 3.0E-20 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_08430 f98be184e1822e5ab55c88ea9e427616 458 SMART SM00388 235 301 2.9E-20 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_08430 f98be184e1822e5ab55c88ea9e427616 458 SMART SM00387 346 458 1.0E-42 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_08430 f98be184e1822e5ab55c88ea9e427616 458 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 347 456 4.4E-30 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_08430 f98be184e1822e5ab55c88ea9e427616 458 SUPERFAMILY SSF55874 291 456 7.47E-49 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_08430 f98be184e1822e5ab55c88ea9e427616 458 Pfam PF00672 HAMP domain 187 229 1.7E-7 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_08430 f98be184e1822e5ab55c88ea9e427616 458 Gene3D G3DSA:1.20.1480.50 144 240 3.0E-14 T 11-10-2018 AFK25_08430 f98be184e1822e5ab55c88ea9e427616 458 SUPERFAMILY SSF158472 182 230 8.24E-9 T 11-10-2018 AFK25_08430 f98be184e1822e5ab55c88ea9e427616 458 Gene3D G3DSA:3.30.565.10 305 458 2.3E-47 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_08430 f98be184e1822e5ab55c88ea9e427616 458 SMART SM00304 182 234 7.6E-9 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_12930 e3019b85254861ca00ca59146b8c120f 425 ProSitePatterns PS00717 Sigma-54 factors family signature 1. 316 335 - T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 AFK25_12930 e3019b85254861ca00ca59146b8c120f 425 PIRSF PIRSF000774 1 425 1.9E-124 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 AFK25_12930 e3019b85254861ca00ca59146b8c120f 425 Pfam PF04963 Sigma-54 factor, core binding domain 69 256 2.0E-50 T 11-10-2018 IPR007046 RNA polymerase sigma factor 54, core-binding domain GO:0003677|GO:0006352 AFK25_12930 e3019b85254861ca00ca59146b8c120f 425 Pfam PF00309 Sigma-54 factor, Activator interacting domain (AID) 5 49 1.9E-12 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 AFK25_12930 e3019b85254861ca00ca59146b8c120f 425 PRINTS PR00045 Sigma-54 factor signature 398 416 1.8E-24 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 AFK25_12930 e3019b85254861ca00ca59146b8c120f 425 PRINTS PR00045 Sigma-54 factor signature 344 355 1.8E-24 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 AFK25_12930 e3019b85254861ca00ca59146b8c120f 425 PRINTS PR00045 Sigma-54 factor signature 142 159 1.8E-24 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 AFK25_12930 e3019b85254861ca00ca59146b8c120f 425 PRINTS PR00045 Sigma-54 factor signature 328 340 1.8E-24 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 AFK25_12930 e3019b85254861ca00ca59146b8c120f 425 Pfam PF04552 Sigma-54, DNA binding domain 269 423 1.1E-55 T 11-10-2018 IPR007634 RNA polymerase sigma factor 54, DNA-binding AFK25_12930 e3019b85254861ca00ca59146b8c120f 425 Gene3D G3DSA:1.10.10.60 363 422 8.2E-24 T 11-10-2018 AFK25_12930 e3019b85254861ca00ca59146b8c120f 425 Gene3D G3DSA:1.10.10.1330 75 184 7.3E-19 T 11-10-2018 IPR038709 RNA polymerase sigma-54 factor, core-binding domain superfamily AFK25_12930 e3019b85254861ca00ca59146b8c120f 425 TIGRFAM TIGR02395 rpoN_sigma: RNA polymerase sigma-54 factor 9 422 1.4E-126 T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 AFK25_12930 e3019b85254861ca00ca59146b8c120f 425 ProSitePatterns PS00718 Sigma-54 factors family signature 2. 403 410 - T 11-10-2018 IPR000394 RNA polymerase sigma factor 54 GO:0001216|GO:0016987 AFK25_02515 70460fb6261bca5348ab30e3c1eb5264 222 Gene3D G3DSA:3.10.350.10 174 222 2.9E-19 T 11-10-2018 IPR036779 LysM domain superfamily AFK25_02515 70460fb6261bca5348ab30e3c1eb5264 222 SUPERFAMILY SSF55846 3 170 9.03E-36 T 11-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFK25_02515 70460fb6261bca5348ab30e3c1eb5264 222 SMART SM00644 14 169 3.1E-29 T 11-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFK25_02515 70460fb6261bca5348ab30e3c1eb5264 222 Gene3D G3DSA:3.40.80.10 4 172 2.4E-39 T 11-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFK25_02515 70460fb6261bca5348ab30e3c1eb5264 222 SUPERFAMILY SSF54106 178 221 1.11E-12 T 11-10-2018 AFK25_02515 70460fb6261bca5348ab30e3c1eb5264 222 SMART SM00257 178 222 1.5E-18 T 11-10-2018 IPR018392 LysM domain AFK25_02515 70460fb6261bca5348ab30e3c1eb5264 222 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 24 154 7.2E-19 T 11-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFK25_02515 70460fb6261bca5348ab30e3c1eb5264 222 Pfam PF01476 LysM domain 179 221 2.1E-17 T 11-10-2018 IPR018392 LysM domain AFK25_03730 6e89b6c33f5ce923f7057fb265724189 170 SUPERFAMILY SSF55144 1 168 6.28E-35 T 11-10-2018 IPR009097 Cyclic phosphodiesterase AFK25_03730 6e89b6c33f5ce923f7057fb265724189 170 Hamap MF_01444 Putative phosphoesterase . 1 168 39.775 T 11-10-2018 IPR022932 Putative phosphoesterase YjcG AFK25_03730 6e89b6c33f5ce923f7057fb265724189 170 Pfam PF13563 2'-5' RNA ligase superfamily 10 155 8.1E-28 T 11-10-2018 AFK25_03730 6e89b6c33f5ce923f7057fb265724189 170 Gene3D G3DSA:3.90.1140.10 2 170 2.9E-49 T 11-10-2018 AFK25_11635 6f1d97f92353f12ccdd30a28d65068ab 586 SUPERFAMILY SSF51621 1 342 4.54E-107 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFK25_11635 6f1d97f92353f12ccdd30a28d65068ab 586 SUPERFAMILY SSF52935 323 473 1.44E-46 T 11-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFK25_11635 6f1d97f92353f12ccdd30a28d65068ab 586 ProSitePatterns PS00110 Pyruvate kinase active site signature. 215 227 - T 11-10-2018 IPR018209 Pyruvate kinase, active site GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFK25_11635 6f1d97f92353f12ccdd30a28d65068ab 586 Gene3D G3DSA:3.20.20.60 4 332 1.3E-155 T 11-10-2018 AFK25_11635 6f1d97f92353f12ccdd30a28d65068ab 586 Gene3D G3DSA:2.40.33.10 71 167 1.3E-155 T 11-10-2018 IPR015806 Pyruvate kinase, insert domain superfamily GO:0004743|GO:0006096 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFK25_11635 6f1d97f92353f12ccdd30a28d65068ab 586 Gene3D G3DSA:3.40.1380.20 340 474 1.7E-49 T 11-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFK25_11635 6f1d97f92353f12ccdd30a28d65068ab 586 SUPERFAMILY SSF50800 70 167 2.27E-27 T 11-10-2018 IPR011037 Pyruvate kinase-like, insert domain superfamily AFK25_11635 6f1d97f92353f12ccdd30a28d65068ab 586 TIGRFAM TIGR01064 pyruv_kin: pyruvate kinase 2 473 7.0E-195 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFK25_11635 6f1d97f92353f12ccdd30a28d65068ab 586 Pfam PF00391 PEP-utilising enzyme, mobile domain 507 576 1.7E-22 T 11-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AFK25_11635 6f1d97f92353f12ccdd30a28d65068ab 586 Pfam PF00224 Pyruvate kinase, barrel domain 1 343 2.4E-163 T 11-10-2018 IPR015793 Pyruvate kinase, barrel GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFK25_11635 6f1d97f92353f12ccdd30a28d65068ab 586 PRINTS PR01050 Pyruvate kinase family signature 59 75 3.2E-81 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFK25_11635 6f1d97f92353f12ccdd30a28d65068ab 586 PRINTS PR01050 Pyruvate kinase family signature 186 200 3.2E-81 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFK25_11635 6f1d97f92353f12ccdd30a28d65068ab 586 PRINTS PR01050 Pyruvate kinase family signature 244 268 3.2E-81 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFK25_11635 6f1d97f92353f12ccdd30a28d65068ab 586 PRINTS PR01050 Pyruvate kinase family signature 313 329 3.2E-81 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFK25_11635 6f1d97f92353f12ccdd30a28d65068ab 586 PRINTS PR01050 Pyruvate kinase family signature 294 312 3.2E-81 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFK25_11635 6f1d97f92353f12ccdd30a28d65068ab 586 PRINTS PR01050 Pyruvate kinase family signature 269 293 3.2E-81 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFK25_11635 6f1d97f92353f12ccdd30a28d65068ab 586 PRINTS PR01050 Pyruvate kinase family signature 217 243 3.2E-81 T 11-10-2018 IPR001697 Pyruvate kinase GO:0000287|GO:0004743|GO:0006096|GO:0030955 KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFK25_11635 6f1d97f92353f12ccdd30a28d65068ab 586 Gene3D G3DSA:3.50.30.10 475 586 1.0E-36 T 11-10-2018 AFK25_11635 6f1d97f92353f12ccdd30a28d65068ab 586 Pfam PF02887 Pyruvate kinase, alpha/beta domain 358 471 7.8E-38 T 11-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AFK25_11635 6f1d97f92353f12ccdd30a28d65068ab 586 SUPERFAMILY SSF52009 466 583 4.84E-31 T 11-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 AFK25_09710 3fda31194bf2988bbc094084d9ef9056 516 SUPERFAMILY SSF52096 4 257 1.02E-82 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFK25_09710 3fda31194bf2988bbc094084d9ef9056 516 Pfam PF01039 Carboxyl transferase domain 29 514 3.5E-196 T 11-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 AFK25_09710 3fda31194bf2988bbc094084d9ef9056 516 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 130 148 3.5E-5 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFK25_09710 3fda31194bf2988bbc094084d9ef9056 516 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 96 110 3.5E-5 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFK25_09710 3fda31194bf2988bbc094084d9ef9056 516 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 195 206 3.5E-5 T 11-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFK25_09710 3fda31194bf2988bbc094084d9ef9056 516 Gene3D G3DSA:3.90.226.10 261 516 2.0E-90 T 11-10-2018 AFK25_09710 3fda31194bf2988bbc094084d9ef9056 516 Gene3D G3DSA:3.90.226.10 1 259 8.9E-99 T 11-10-2018 AFK25_09710 3fda31194bf2988bbc094084d9ef9056 516 SUPERFAMILY SSF52096 244 516 4.44E-90 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFK25_05320 5518f63bf577d285d96e553ba096d276 162 Pfam PF01252 Signal peptidase (SPase) II 7 144 1.1E-38 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFK25_05320 5518f63bf577d285d96e553ba096d276 162 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 45 53 2.5E-17 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFK25_05320 5518f63bf577d285d96e553ba096d276 162 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 125 141 2.5E-17 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFK25_05320 5518f63bf577d285d96e553ba096d276 162 PRINTS PR00781 Lipoprotein signal peptidase family (A8) signature 89 104 2.5E-17 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFK25_05320 5518f63bf577d285d96e553ba096d276 162 TIGRFAM TIGR00077 lspA: signal peptidase II 2 151 2.5E-47 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFK25_05320 5518f63bf577d285d96e553ba096d276 162 Hamap MF_00161 Lipoprotein signal peptidase [lspA]. 1 150 16.665 T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFK25_05320 5518f63bf577d285d96e553ba096d276 162 ProSitePatterns PS00855 Signal peptidases II signature. 92 104 - T 11-10-2018 IPR001872 Peptidase A8, signal peptidase II GO:0004190|GO:0006508|GO:0016020 MetaCyc: PWY-7884 AFK25_00595 acb7c317bb845d01171a36cc713eaa11 395 Pfam PF03143 Elongation factor Tu C-terminal domain 299 393 1.1E-34 T 11-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal AFK25_00595 acb7c317bb845d01171a36cc713eaa11 395 TIGRFAM TIGR00485 EF-Tu: translation elongation factor Tu 1 395 2.0E-238 T 11-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFK25_00595 acb7c317bb845d01171a36cc713eaa11 395 Pfam PF00009 Elongation factor Tu GTP binding domain 10 201 8.2E-63 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_00595 acb7c317bb845d01171a36cc713eaa11 395 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 146 3.2E-16 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFK25_00595 acb7c317bb845d01171a36cc713eaa11 395 SUPERFAMILY SSF50465 299 394 3.74E-36 T 11-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal AFK25_00595 acb7c317bb845d01171a36cc713eaa11 395 Gene3D G3DSA:2.40.30.10 206 335 4.4E-55 T 11-10-2018 AFK25_00595 acb7c317bb845d01171a36cc713eaa11 395 SUPERFAMILY SSF52540 9 226 1.89E-64 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_00595 acb7c317bb845d01171a36cc713eaa11 395 Gene3D G3DSA:2.40.30.10 339 394 1.0E-27 T 11-10-2018 AFK25_00595 acb7c317bb845d01171a36cc713eaa11 395 Gene3D G3DSA:3.40.50.300 1 203 9.3E-73 T 11-10-2018 AFK25_00595 acb7c317bb845d01171a36cc713eaa11 395 Hamap MF_00118_B Elongation factor Tu [tuf]. 1 395 61.97 T 11-10-2018 IPR004541 Translation elongation factor EFTu/EF1A, bacterial/organelle GO:0003746|GO:0005525|GO:0005622|GO:0006414 Reactome: R-HSA-5389840 AFK25_00595 acb7c317bb845d01171a36cc713eaa11 395 Pfam PF03144 Elongation factor Tu domain 2 225 294 4.2E-19 T 11-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AFK25_00595 acb7c317bb845d01171a36cc713eaa11 395 SUPERFAMILY SSF50447 203 302 9.62E-32 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFK25_00595 acb7c317bb845d01171a36cc713eaa11 395 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 51 66 - T 11-10-2018 IPR031157 Tr-type G domain, conserved site AFK25_00595 acb7c317bb845d01171a36cc713eaa11 395 PRINTS PR00315 GTP-binding elongation factor signature 94 105 3.1E-25 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_00595 acb7c317bb845d01171a36cc713eaa11 395 PRINTS PR00315 GTP-binding elongation factor signature 58 66 3.1E-25 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_00595 acb7c317bb845d01171a36cc713eaa11 395 PRINTS PR00315 GTP-binding elongation factor signature 131 140 3.1E-25 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_00595 acb7c317bb845d01171a36cc713eaa11 395 PRINTS PR00315 GTP-binding elongation factor signature 78 88 3.1E-25 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_00595 acb7c317bb845d01171a36cc713eaa11 395 PRINTS PR00315 GTP-binding elongation factor signature 14 27 3.1E-25 T 11-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AFK25_07135 deacf79d56418de633336a37eae4f4e2 223 Gene3D G3DSA:3.40.50.300 11 221 1.8E-61 T 11-10-2018 AFK25_07135 deacf79d56418de633336a37eae4f4e2 223 SUPERFAMILY SSF52540 21 211 8.65E-36 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_07135 deacf79d56418de633336a37eae4f4e2 223 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 2 211 3.8E-85 T 11-10-2018 IPR004392 Hydrogenase maturation factor HypB GO:0016151|GO:0051604 AFK25_07135 deacf79d56418de633336a37eae4f4e2 223 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 31 191 3.3E-28 T 11-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain AFK25_07135 deacf79d56418de633336a37eae4f4e2 223 PIRSF PIRSF005624 1 223 4.1E-88 T 11-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 AFK25_14035 dc7413e7a0489ed58b0888177331170e 556 SMART SM01016 9 95 3.3E-36 T 11-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFK25_14035 dc7413e7a0489ed58b0888177331170e 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 163 176 1.9E-24 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFK25_14035 dc7413e7a0489ed58b0888177331170e 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 306 327 1.9E-24 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFK25_14035 dc7413e7a0489ed58b0888177331170e 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 139 155 1.9E-24 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFK25_14035 dc7413e7a0489ed58b0888177331170e 556 PRINTS PR01038 Arginyl-tRNA synthetase signature 124 139 1.9E-24 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFK25_14035 dc7413e7a0489ed58b0888177331170e 556 Hamap MF_00123 Arginine--tRNA ligase [argS]. 5 556 28.347 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFK25_14035 dc7413e7a0489ed58b0888177331170e 556 Gene3D G3DSA:1.10.730.10 432 556 1.1E-176 T 11-10-2018 AFK25_14035 dc7413e7a0489ed58b0888177331170e 556 SUPERFAMILY SSF52374 118 448 6.76E-101 T 11-10-2018 AFK25_14035 dc7413e7a0489ed58b0888177331170e 556 Pfam PF00750 tRNA synthetases class I (R) 104 400 4.2E-30 T 11-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 AFK25_14035 dc7413e7a0489ed58b0888177331170e 556 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 7 556 4.7E-176 T 11-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AFK25_14035 dc7413e7a0489ed58b0888177331170e 556 Gene3D G3DSA:3.40.50.620 124 431 1.1E-176 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_14035 dc7413e7a0489ed58b0888177331170e 556 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 134 143 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_14035 dc7413e7a0489ed58b0888177331170e 556 SMART SM00836 437 556 1.6E-50 T 11-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 AFK25_14035 dc7413e7a0489ed58b0888177331170e 556 SUPERFAMILY SSF47323 432 556 2.29E-34 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_14035 dc7413e7a0489ed58b0888177331170e 556 Gene3D G3DSA:3.30.1360.70 2 113 5.5E-29 T 11-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 AFK25_14035 dc7413e7a0489ed58b0888177331170e 556 SUPERFAMILY SSF55190 1 115 1.01E-27 T 11-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 AFK25_14035 dc7413e7a0489ed58b0888177331170e 556 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 8 94 8.7E-26 T 11-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFK25_14035 dc7413e7a0489ed58b0888177331170e 556 Pfam PF05746 DALR anticodon binding domain 438 556 2.3E-37 T 11-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 AFK25_11645 3d91ddbb2cefc6c087dda42dcb438461 325 Gene3D G3DSA:3.90.226.10 2 317 5.4E-126 T 11-10-2018 AFK25_11645 3d91ddbb2cefc6c087dda42dcb438461 325 Pfam PF03255 Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit 5 147 4.5E-67 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFK25_11645 3d91ddbb2cefc6c087dda42dcb438461 325 TIGRFAM TIGR00513 accA: acetyl-CoA carboxylase, carboxyl transferase, alpha subunit 3 319 5.1E-161 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFK25_11645 3d91ddbb2cefc6c087dda42dcb438461 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 133 149 2.6E-47 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFK25_11645 3d91ddbb2cefc6c087dda42dcb438461 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 87 98 2.6E-47 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFK25_11645 3d91ddbb2cefc6c087dda42dcb438461 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 168 181 2.6E-47 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFK25_11645 3d91ddbb2cefc6c087dda42dcb438461 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 196 205 2.6E-47 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFK25_11645 3d91ddbb2cefc6c087dda42dcb438461 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 112 130 2.6E-47 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFK25_11645 3d91ddbb2cefc6c087dda42dcb438461 325 PRINTS PR01069 Acetyl-CoA carboxylase carboxyl transferase alpha subunit signature 152 165 2.6E-47 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFK25_11645 3d91ddbb2cefc6c087dda42dcb438461 325 Hamap MF_00823 Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha [accA]. 4 315 50.061 T 11-10-2018 IPR001095 Acetyl-CoA carboxylase, alpha subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AFK25_11645 3d91ddbb2cefc6c087dda42dcb438461 325 SUPERFAMILY SSF52096 6 315 6.08E-103 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFK25_08050 19861a5a446a73c82a44d7f2d9717ffe 301 SUPERFAMILY SSF53807 27 299 3.04E-80 T 11-10-2018 AFK25_08050 19861a5a446a73c82a44d7f2d9717ffe 301 Gene3D G3DSA:3.40.50.1980 166 299 1.3E-47 T 11-10-2018 AFK25_08050 19861a5a446a73c82a44d7f2d9717ffe 301 Pfam PF01297 Zinc-uptake complex component A periplasmic 29 297 2.1E-74 T 11-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 AFK25_08050 19861a5a446a73c82a44d7f2d9717ffe 301 PRINTS PR00691 Adhesin B signature 70 89 3.7E-22 T 11-10-2018 IPR006129 Adhesin B GO:0007155 AFK25_08050 19861a5a446a73c82a44d7f2d9717ffe 301 PRINTS PR00691 Adhesin B signature 51 69 3.7E-22 T 11-10-2018 IPR006129 Adhesin B GO:0007155 AFK25_08050 19861a5a446a73c82a44d7f2d9717ffe 301 PRINTS PR00691 Adhesin B signature 256 274 3.7E-22 T 11-10-2018 IPR006129 Adhesin B GO:0007155 AFK25_08050 19861a5a446a73c82a44d7f2d9717ffe 301 PRINTS PR00691 Adhesin B signature 180 197 3.7E-22 T 11-10-2018 IPR006129 Adhesin B GO:0007155 AFK25_08050 19861a5a446a73c82a44d7f2d9717ffe 301 PRINTS PR00691 Adhesin B signature 277 295 3.7E-22 T 11-10-2018 IPR006129 Adhesin B GO:0007155 AFK25_08050 19861a5a446a73c82a44d7f2d9717ffe 301 PRINTS PR00691 Adhesin B signature 26 47 3.7E-22 T 11-10-2018 IPR006129 Adhesin B GO:0007155 AFK25_08050 19861a5a446a73c82a44d7f2d9717ffe 301 PRINTS PR00690 Adhesin family signature 180 201 1.8E-41 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFK25_08050 19861a5a446a73c82a44d7f2d9717ffe 301 PRINTS PR00690 Adhesin family signature 70 87 1.8E-41 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFK25_08050 19861a5a446a73c82a44d7f2d9717ffe 301 PRINTS PR00690 Adhesin family signature 264 283 1.8E-41 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFK25_08050 19861a5a446a73c82a44d7f2d9717ffe 301 PRINTS PR00690 Adhesin family signature 233 251 1.8E-41 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFK25_08050 19861a5a446a73c82a44d7f2d9717ffe 301 PRINTS PR00690 Adhesin family signature 26 44 1.8E-41 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFK25_08050 19861a5a446a73c82a44d7f2d9717ffe 301 PRINTS PR00690 Adhesin family signature 57 70 1.8E-41 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFK25_08050 19861a5a446a73c82a44d7f2d9717ffe 301 Gene3D G3DSA:3.40.50.1980 26 165 1.0E-47 T 11-10-2018 AFK25_12815 9b524281e979d6bad2a97703acb8d729 305 PIRSF PIRSF000196 1 305 4.4E-138 T 11-10-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 AFK25_12815 9b524281e979d6bad2a97703acb8d729 305 Pfam PF01619 Proline dehydrogenase 44 298 2.8E-38 T 11-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 AFK25_12815 9b524281e979d6bad2a97703acb8d729 305 SUPERFAMILY SSF51730 37 300 5.1E-78 T 11-10-2018 IPR029041 FAD-linked oxidoreductase-like AFK25_12815 9b524281e979d6bad2a97703acb8d729 305 Gene3D G3DSA:3.20.20.530 19 305 7.4E-101 T 11-10-2018 AFK25_09240 2a1b02934b34e6f2b08ce06e74aa473b 245 Pfam PF01479 S4 domain 2 48 7.4E-16 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_09240 2a1b02934b34e6f2b08ce06e74aa473b 245 SMART SM00363 2 65 4.9E-17 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_09240 2a1b02934b34e6f2b08ce06e74aa473b 245 Pfam PF00849 RNA pseudouridylate synthase 62 196 3.8E-26 T 11-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_09240 2a1b02934b34e6f2b08ce06e74aa473b 245 SUPERFAMILY SSF55120 46 235 3.6E-47 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_09240 2a1b02934b34e6f2b08ce06e74aa473b 245 Gene3D G3DSA:3.10.290.10 1 63 3.2E-23 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFK25_09240 2a1b02934b34e6f2b08ce06e74aa473b 245 Gene3D G3DSA:3.30.70.1560 123 215 4.6E-58 T 11-10-2018 AFK25_09240 2a1b02934b34e6f2b08ce06e74aa473b 245 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 66 226 2.7E-54 T 11-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 AFK25_09240 2a1b02934b34e6f2b08ce06e74aa473b 245 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 99 113 - T 11-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 AFK25_09240 2a1b02934b34e6f2b08ce06e74aa473b 245 Gene3D G3DSA:3.30.70.580 64 223 4.6E-58 T 11-10-2018 AFK25_09240 2a1b02934b34e6f2b08ce06e74aa473b 245 SUPERFAMILY SSF55174 2 67 6.08E-18 T 11-10-2018 AFK25_01455 d469fd62292cab4f2b680be502a2edff 502 Pfam PF01966 HD domain 330 454 1.8E-21 T 11-10-2018 IPR006674 HD domain AFK25_01455 d469fd62292cab4f2b680be502a2edff 502 SMART SM00471 325 463 1.2E-14 T 11-10-2018 IPR003607 HD/PDEase domain AFK25_01455 d469fd62292cab4f2b680be502a2edff 502 Gene3D G3DSA:1.10.3210.10 303 501 2.6E-74 T 11-10-2018 AFK25_01455 d469fd62292cab4f2b680be502a2edff 502 SUPERFAMILY SSF109604 318 494 7.54E-44 T 11-10-2018 AFK25_11380 971552f9da1d6ad0e3fe127156202595 250 Pfam PF00588 SpoU rRNA Methylase family 107 245 1.2E-33 T 11-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AFK25_11380 971552f9da1d6ad0e3fe127156202595 250 SMART SM00967 31 100 1.6E-17 T 11-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 AFK25_11380 971552f9da1d6ad0e3fe127156202595 250 Gene3D G3DSA:3.30.1330.30 2 96 1.0E-27 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like AFK25_11380 971552f9da1d6ad0e3fe127156202595 250 SUPERFAMILY SSF75217 100 248 5.04E-38 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases AFK25_11380 971552f9da1d6ad0e3fe127156202595 250 Gene3D G3DSA:3.40.1280.10 97 250 3.5E-48 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFK25_11380 971552f9da1d6ad0e3fe127156202595 250 Pfam PF08032 RNA 2'-O ribose methyltransferase substrate binding 31 97 7.6E-15 T 11-10-2018 IPR013123 RNA 2-O ribose methyltransferase, substrate binding GO:0008168 Reactome: R-HSA-6793080 AFK25_11380 971552f9da1d6ad0e3fe127156202595 250 SUPERFAMILY SSF55315 2 97 5.41E-27 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like AFK25_13240 bdc743901ae39dbbaa618d05a0dca32f 299 Pfam PF00700 Bacterial flagellin C-terminal helical region 217 298 9.9E-8 T 11-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 AFK25_13240 bdc743901ae39dbbaa618d05a0dca32f 299 SUPERFAMILY SSF64518 1 299 7.72E-70 T 11-10-2018 AFK25_13240 bdc743901ae39dbbaa618d05a0dca32f 299 TIGRFAM TIGR02550 flagell_flgL: flagellar hook-associated protein 3 2 188 3.7E-54 T 11-10-2018 IPR013384 Flagellar hook-associated protein 3 GO:0009424|GO:0071973 AFK25_13240 bdc743901ae39dbbaa618d05a0dca32f 299 Pfam PF00669 Bacterial flagellin N-terminal helical region 5 140 4.0E-24 T 11-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 AFK25_13240 bdc743901ae39dbbaa618d05a0dca32f 299 Gene3D G3DSA:1.20.1330.10 40 245 1.1E-51 T 11-10-2018 AFK25_00460 f173715b8966859656fc23a3fb5358e0 354 Hamap MF_00602 Protein-arginine kinase [mcsB]. 13 351 39.276 T 11-10-2018 IPR023660 Protein arginine kinase GO:0016775 AFK25_00460 f173715b8966859656fc23a3fb5358e0 354 Gene3D G3DSA:3.30.590.10 12 264 3.8E-75 T 11-10-2018 AFK25_00460 f173715b8966859656fc23a3fb5358e0 354 Pfam PF00217 ATP:guanido phosphotransferase, C-terminal catalytic domain 67 254 4.5E-75 T 11-10-2018 IPR022414 ATP:guanido phosphotransferase, catalytic domain GO:0016301|GO:0016772 Reactome: R-HSA-71288 AFK25_00460 f173715b8966859656fc23a3fb5358e0 354 SUPERFAMILY SSF55931 8 269 5.61E-90 T 11-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AFK25_00460 f173715b8966859656fc23a3fb5358e0 354 ProSitePatterns PS00112 Phosphagen kinase active site signature. 168 174 - T 11-10-2018 IPR022415 ATP:guanido phosphotransferase active site GO:0016301|GO:0016772 Reactome: R-HSA-71288 AFK25_03555 b5590050b41be579e6d67e0d447690d5 292 Gene3D G3DSA:3.30.2350.10 81 292 1.3E-68 T 11-10-2018 AFK25_03555 b5590050b41be579e6d67e0d447690d5 292 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 17 292 2.8E-76 T 11-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_03555 b5590050b41be579e6d67e0d447690d5 292 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 131 145 - T 11-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_03555 b5590050b41be579e6d67e0d447690d5 292 SUPERFAMILY SSF55120 74 291 3.84E-71 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_03555 b5590050b41be579e6d67e0d447690d5 292 Pfam PF00849 RNA pseudouridylate synthase 89 239 3.4E-29 T 11-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_02390 d63900a67a14eb4bb58dcf4cfbaf1086 360 Gene3D G3DSA:3.90.226.10 2 194 5.1E-55 T 11-10-2018 AFK25_02390 d63900a67a14eb4bb58dcf4cfbaf1086 360 Pfam PF00574 Clp protease 48 185 4.4E-37 T 11-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA AFK25_02390 d63900a67a14eb4bb58dcf4cfbaf1086 360 SUPERFAMILY SSF52096 6 187 1.52E-53 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFK25_02390 d63900a67a14eb4bb58dcf4cfbaf1086 360 PRINTS PR00127 Clp protease catalytic subunit P signature 162 181 3.6E-11 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFK25_02390 d63900a67a14eb4bb58dcf4cfbaf1086 360 PRINTS PR00127 Clp protease catalytic subunit P signature 55 75 3.6E-11 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFK25_02390 d63900a67a14eb4bb58dcf4cfbaf1086 360 PRINTS PR00127 Clp protease catalytic subunit P signature 86 103 3.6E-11 T 11-10-2018 IPR001907 ATP-dependent Clp protease proteolytic subunit GO:0004252|GO:0006508 AFK25_08350 caded48faf167964cc63372b4ae4598c 154 SUPERFAMILY SSF55136 1 150 2.22E-17 T 11-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily AFK25_08350 caded48faf167964cc63372b4ae4598c 154 SMART SM00871 1 151 9.8E-18 T 11-10-2018 IPR010499 Bacterial transcription activator, effector binding AFK25_08350 caded48faf167964cc63372b4ae4598c 154 Gene3D G3DSA:3.20.80.10 1 152 7.8E-28 T 11-10-2018 IPR011256 Regulatory factor, effector binding domain superfamily AFK25_08350 caded48faf167964cc63372b4ae4598c 154 Pfam PF06445 GyrI-like small molecule binding domain 1 150 1.5E-17 T 11-10-2018 IPR029442 GyrI-like small molecule binding domain AFK25_05910 c47b433bca5eeb442d6f48c376cdfca0 323 TIGRFAM TIGR00083 ribF: riboflavin biosynthesis protein RibF 19 310 4.1E-98 T 11-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 AFK25_05910 c47b433bca5eeb442d6f48c376cdfca0 323 SMART SM00904 183 310 9.6E-63 T 11-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 AFK25_05910 c47b433bca5eeb442d6f48c376cdfca0 323 Gene3D G3DSA:3.40.50.620 4 187 2.0E-53 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_05910 c47b433bca5eeb442d6f48c376cdfca0 323 SUPERFAMILY SSF82114 174 312 6.76E-47 T 11-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 AFK25_05910 c47b433bca5eeb442d6f48c376cdfca0 323 Pfam PF06574 FAD synthetase 12 166 4.9E-50 T 11-10-2018 IPR015864 FAD synthetase GO:0003919|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 AFK25_05910 c47b433bca5eeb442d6f48c376cdfca0 323 PIRSF PIRSF004491 1 314 8.8E-106 T 11-10-2018 IPR002606 Riboflavin kinase, bacterial GO:0003919|GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26+2.7.7.2|MetaCyc: PWY-5523|MetaCyc: PWY-6167|MetaCyc: PWY-6168|MetaCyc: PWY-7863 AFK25_05910 c47b433bca5eeb442d6f48c376cdfca0 323 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 19 57 1.1E-9 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFK25_05910 c47b433bca5eeb442d6f48c376cdfca0 323 SUPERFAMILY SSF52374 17 181 3.1E-30 T 11-10-2018 AFK25_05910 c47b433bca5eeb442d6f48c376cdfca0 323 Gene3D G3DSA:2.40.30.30 188 319 6.5E-44 T 11-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 AFK25_05910 c47b433bca5eeb442d6f48c376cdfca0 323 Pfam PF01687 Riboflavin kinase 184 309 1.0E-37 T 11-10-2018 IPR015865 Riboflavin kinase domain, bacterial/eukaryotic GO:0008531|GO:0009231 KEGG: 00740+2.7.1.26|MetaCyc: PWY-5523|MetaCyc: PWY-6168|MetaCyc: PWY-7863|Reactome: R-HSA-196843 AFK25_10945 59a5f78570606154b015368682f3fb49 268 PIRSF PIRSF003092 1 268 1.2E-97 T 11-10-2018 IPR025501 ATP binding protein MinD AFK25_10945 59a5f78570606154b015368682f3fb49 268 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 220 5.8E-26 T 11-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AFK25_10945 59a5f78570606154b015368682f3fb49 268 TIGRFAM TIGR01968 minD_bact: septum site-determining protein MinD 3 265 2.4E-124 T 11-10-2018 IPR010223 ATP binding protein MinD, bacterial-type GO:0016887 AFK25_10945 59a5f78570606154b015368682f3fb49 268 Gene3D G3DSA:3.40.50.300 3 253 6.9E-74 T 11-10-2018 AFK25_10945 59a5f78570606154b015368682f3fb49 268 SUPERFAMILY SSF52540 5 249 3.73E-61 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_10345 c725b200e96cb1add4dde7a35c3e102a 220 Pfam PF01957 NfeD-like C-terminal, partner-binding 65 212 6.0E-12 T 11-10-2018 IPR002810 NfeD-like, C-terminal domain AFK25_10345 c725b200e96cb1add4dde7a35c3e102a 220 SUPERFAMILY SSF141322 153 213 2.22E-6 T 11-10-2018 AFK25_10345 c725b200e96cb1add4dde7a35c3e102a 220 Gene3D G3DSA:2.40.50.140 152 219 5.9E-8 T 11-10-2018 AFK25_10410 8e0b0f2bcb03cd07de0b989b11f17fcf 386 SUPERFAMILY SSF53187 201 372 6.28E-8 T 11-10-2018 AFK25_10410 8e0b0f2bcb03cd07de0b989b11f17fcf 386 TIGRFAM TIGR02867 spore_II_P: stage II sporulation protein P 169 372 1.3E-77 T 11-10-2018 IPR010897 Sporulation stage II, protein P AFK25_10410 8e0b0f2bcb03cd07de0b989b11f17fcf 386 Pfam PF07454 Stage II sporulation protein P (SpoIIP) 95 368 1.2E-78 T 11-10-2018 IPR010897 Sporulation stage II, protein P AFK25_10100 9c0aca8f023022f9bb5492bae14483fd 509 Pfam PF01694 Rhomboid family 221 357 4.5E-36 T 11-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 AFK25_10100 9c0aca8f023022f9bb5492bae14483fd 509 Gene3D G3DSA:1.25.40.10 367 509 5.0E-15 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_10100 9c0aca8f023022f9bb5492bae14483fd 509 SMART SM00028 428 461 47.0 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_10100 9c0aca8f023022f9bb5492bae14483fd 509 SMART SM00028 462 495 1.3E-4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_10100 9c0aca8f023022f9bb5492bae14483fd 509 SUPERFAMILY SSF48452 396 506 5.06E-18 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_10100 9c0aca8f023022f9bb5492bae14483fd 509 SUPERFAMILY SSF144091 180 358 3.92E-45 T 11-10-2018 AFK25_10100 9c0aca8f023022f9bb5492bae14483fd 509 Gene3D G3DSA:1.20.1540.10 174 365 5.1E-52 T 11-10-2018 IPR035952 Rhomboid-like superfamily AFK25_10100 9c0aca8f023022f9bb5492bae14483fd 509 Pfam PF14559 Tetratricopeptide repeat 439 502 1.7E-8 T 11-10-2018 AFK25_10085 890bebe86ff6d3997091e2c5763a56cf 77 Gene3D G3DSA:1.10.287.760 1 71 1.3E-28 T 11-10-2018 IPR023164 YqgQ-like superfamily AFK25_10085 890bebe86ff6d3997091e2c5763a56cf 77 SUPERFAMILY SSF158379 1 62 3.4E-24 T 11-10-2018 IPR023164 YqgQ-like superfamily AFK25_10085 890bebe86ff6d3997091e2c5763a56cf 77 Pfam PF06014 Bacterial protein of unknown function (DUF910) 1 61 1.1E-29 T 11-10-2018 IPR009256 Protein of unknown function DUF910 AFK25_02875 ed68b823a6b68d0486716d62721f7147 346 ProSitePatterns PS00906 Uroporphyrinogen decarboxylase signature 1. 20 29 - T 11-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFK25_02875 ed68b823a6b68d0486716d62721f7147 346 Hamap MF_00218 Uroporphyrinogen decarboxylase [hemE]. 4 341 47.589 T 11-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFK25_02875 ed68b823a6b68d0486716d62721f7147 346 TIGRFAM TIGR01464 hemE: uroporphyrinogen decarboxylase 6 339 2.8E-128 T 11-10-2018 IPR006361 Uroporphyrinogen decarboxylase HemE GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFK25_02875 ed68b823a6b68d0486716d62721f7147 346 SUPERFAMILY SSF51726 1 343 7.19E-106 T 11-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AFK25_02875 ed68b823a6b68d0486716d62721f7147 346 Gene3D G3DSA:3.20.20.210 1 346 3.0E-148 T 11-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AFK25_02875 ed68b823a6b68d0486716d62721f7147 346 ProSitePatterns PS00907 Uroporphyrinogen decarboxylase signature 2. 138 154 - T 11-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFK25_02875 ed68b823a6b68d0486716d62721f7147 346 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 3 340 8.2E-128 T 11-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AFK25_06220 4d5aa2076d5ce6200759c286d0cbbfa7 208 Pfam PF13353 4Fe-4S single cluster domain 14 152 1.3E-31 T 11-10-2018 AFK25_06220 4d5aa2076d5ce6200759c286d0cbbfa7 208 SUPERFAMILY SSF102114 26 102 3.53E-10 T 11-10-2018 AFK25_06220 4d5aa2076d5ce6200759c286d0cbbfa7 208 Gene3D G3DSA:3.20.20.70 2 179 7.1E-32 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_06220 4d5aa2076d5ce6200759c286d0cbbfa7 208 Pfam PF04055 Radical SAM superfamily 26 98 1.0E-7 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFK25_09005 5545282b186e24557e221321ff40bfd5 349 SMART SM01240 21 336 1.5E-5 T 11-10-2018 AFK25_09005 5545282b186e24557e221321ff40bfd5 349 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 3 330 38.31 T 11-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 AFK25_09005 5545282b186e24557e221321ff40bfd5 349 Pfam PF01070 FMN-dependent dehydrogenase 166 323 1.0E-18 T 11-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 AFK25_09005 5545282b186e24557e221321ff40bfd5 349 PIRSF PIRSF003314 1 340 1.0E-124 T 11-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 AFK25_09005 5545282b186e24557e221321ff40bfd5 349 Gene3D G3DSA:3.20.20.70 2 349 1.3E-129 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_09005 5545282b186e24557e221321ff40bfd5 349 SUPERFAMILY SSF51395 22 346 2.15E-88 T 11-10-2018 AFK25_09005 5545282b186e24557e221321ff40bfd5 349 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 5 329 3.7E-122 T 11-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 AFK25_00075 5fff83eb4560ef24b8ce273242c3ea20 425 SMART SM00936 294 395 1.2E-19 T 11-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFK25_00075 5fff83eb4560ef24b8ce273242c3ea20 425 SUPERFAMILY SSF56601 12 294 9.34E-77 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFK25_00075 5fff83eb4560ef24b8ce273242c3ea20 425 Pfam PF07943 Penicillin-binding protein 5, C-terminal domain 294 395 7.2E-20 T 11-10-2018 IPR012907 Peptidase S11, D-Ala-D-Ala carboxypeptidase A, C-terminal GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFK25_00075 5fff83eb4560ef24b8ce273242c3ea20 425 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 15 270 4.5E-90 T 11-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 AFK25_00075 5fff83eb4560ef24b8ce273242c3ea20 425 SUPERFAMILY SSF69189 286 377 1.06E-20 T 11-10-2018 IPR015956 Penicillin-binding protein, C-terminal domain superfamily GO:0004180|GO:0006508 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFK25_00075 5fff83eb4560ef24b8ce273242c3ea20 425 Gene3D G3DSA:2.60.410.10 295 395 5.1E-21 T 11-10-2018 IPR037167 D-Ala-D-Ala carboxypeptidase, C-terminal domain superfamily GO:0006508|GO:0009002 KEGG: 00550+3.4.16.4|MetaCyc: PWY-5265|MetaCyc: PWY-6471 AFK25_00075 5fff83eb4560ef24b8ce273242c3ea20 425 Gene3D G3DSA:3.40.710.10 6 293 6.1E-92 T 11-10-2018 AFK25_00075 5fff83eb4560ef24b8ce273242c3ea20 425 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 106 123 7.6E-16 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFK25_00075 5fff83eb4560ef24b8ce273242c3ea20 425 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 49 60 7.6E-16 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFK25_00075 5fff83eb4560ef24b8ce273242c3ea20 425 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 133 146 7.6E-16 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFK25_06755 3aa742c6922f097cf90ee2450942a1f1 578 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 174 8.1E-40 T 11-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AFK25_06755 3aa742c6922f097cf90ee2450942a1f1 578 Gene3D G3DSA:3.40.50.920 466 578 2.5E-30 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFK25_06755 3aa742c6922f097cf90ee2450942a1f1 578 Gene3D G3DSA:3.40.920.10 1 184 1.6E-27 T 11-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AFK25_06755 3aa742c6922f097cf90ee2450942a1f1 578 SUPERFAMILY SSF52922 468 577 9.29E-26 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFK25_06755 3aa742c6922f097cf90ee2450942a1f1 578 SUPERFAMILY SSF52518 196 457 2.54E-75 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold AFK25_06755 3aa742c6922f097cf90ee2450942a1f1 578 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 475 568 1.2E-11 T 11-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II AFK25_06755 3aa742c6922f097cf90ee2450942a1f1 578 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 5 573 1.0E-216 T 11-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 AFK25_06755 3aa742c6922f097cf90ee2450942a1f1 578 SUPERFAMILY SSF53323 1 221 7.72E-44 T 11-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AFK25_06755 3aa742c6922f097cf90ee2450942a1f1 578 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 210 450 2.2E-63 T 11-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 AFK25_06755 3aa742c6922f097cf90ee2450942a1f1 578 Gene3D G3DSA:3.40.50.970 185 386 1.8E-78 T 11-10-2018 AFK25_10355 99664ef2605df68ba06a86da8b8e893e 57 ProSitePatterns PS01181 Ribosomal protein S21 signature. 13 25 - T 11-10-2018 IPR018278 Ribosomal protein S21, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_10355 99664ef2605df68ba06a86da8b8e893e 57 Gene3D G3DSA:1.20.5.1150 16 56 4.3E-18 T 11-10-2018 IPR038380 Ribosomal protein S21 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10355 99664ef2605df68ba06a86da8b8e893e 57 ProDom PD005521 RIBOSOMAL S21 RIBONUCLEOPROTEIN 30S S21P A SSU SUBUNIT SEQUENCING DIRECT 16 43 2.0E-8 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10355 99664ef2605df68ba06a86da8b8e893e 57 Pfam PF01165 Ribosomal protein S21 6 57 1.4E-20 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10355 99664ef2605df68ba06a86da8b8e893e 57 TIGRFAM TIGR00030 S21p: ribosomal protein bS21 3 57 1.8E-21 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10355 99664ef2605df68ba06a86da8b8e893e 57 PRINTS PR00976 Ribosomal protein S21 family signature 13 22 2.5E-15 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10355 99664ef2605df68ba06a86da8b8e893e 57 PRINTS PR00976 Ribosomal protein S21 family signature 25 35 2.5E-15 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10355 99664ef2605df68ba06a86da8b8e893e 57 PRINTS PR00976 Ribosomal protein S21 family signature 5 13 2.5E-15 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10355 99664ef2605df68ba06a86da8b8e893e 57 PRINTS PR00976 Ribosomal protein S21 family signature 37 47 2.5E-15 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10355 99664ef2605df68ba06a86da8b8e893e 57 Hamap MF_00358 30S ribosomal protein S21 [rpsU]. 1 57 20.627 T 11-10-2018 IPR001911 Ribosomal protein S21 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_11005 0ed10d364cac32b2cd857f8673e66790 249 Pfam PF01478 Type IV leader peptidase family 103 206 1.1E-17 T 11-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 AFK25_11005 0ed10d364cac32b2cd857f8673e66790 249 Pfam PF06750 Bacterial Peptidase A24 N-terminal domain 8 87 1.0E-31 T 11-10-2018 IPR010627 Peptidase A24A, N-terminal AFK25_11005 0ed10d364cac32b2cd857f8673e66790 249 ProSitePatterns PS00195 Glutaredoxin active site. 31 47 - T 11-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 AFK25_06315 2b900d2c4e3dc4659e561debe0af7395 469 PIRSF PIRSF026631 1 469 1.4E-97 T 11-10-2018 IPR014529 Uncharacterised conserved protein UCP026631 AFK25_06315 2b900d2c4e3dc4659e561debe0af7395 469 Pfam PF03703 Bacterial PH domain 66 146 8.4E-17 T 11-10-2018 IPR005182 Domain of unknown function DUF304 AFK25_06315 2b900d2c4e3dc4659e561debe0af7395 469 Pfam PF03703 Bacterial PH domain 242 326 1.4E-11 T 11-10-2018 IPR005182 Domain of unknown function DUF304 AFK25_06315 2b900d2c4e3dc4659e561debe0af7395 469 Pfam PF03703 Bacterial PH domain 387 463 9.7E-14 T 11-10-2018 IPR005182 Domain of unknown function DUF304 AFK25_05765 06ab857af3f297fa1745235acf1ddb0c 368 Gene3D G3DSA:3.40.50.300 168 352 6.9E-84 T 11-10-2018 AFK25_05765 06ab857af3f297fa1745235acf1ddb0c 368 SMART SM00382 172 341 0.0039 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_05765 06ab857af3f297fa1745235acf1ddb0c 368 Gene3D G3DSA:1.20.120.1380 116 355 6.9E-84 T 11-10-2018 AFK25_05765 06ab857af3f297fa1745235acf1ddb0c 368 Pfam PF00448 SRP54-type protein, GTPase domain 176 362 6.1E-43 T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFK25_05765 06ab857af3f297fa1745235acf1ddb0c 368 SUPERFAMILY SSF52540 173 363 1.12E-33 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_05765 06ab857af3f297fa1745235acf1ddb0c 368 SMART SM00962 173 364 6.4E-60 T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFK25_06070 6a543cea6b7a0987f24b8f006213dc2b 288 Pfam PF03773 Predicted permease 3 285 6.6E-50 T 11-10-2018 IPR005524 Predicted permease DUF318 AFK25_08105 e50487937df1b34a501b16f1aeb8caaa 128 Pfam PF13411 MerR HTH family regulatory protein 4 69 1.0E-19 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_08105 e50487937df1b34a501b16f1aeb8caaa 128 SMART SM00422 4 72 9.1E-29 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_08105 e50487937df1b34a501b16f1aeb8caaa 128 SUPERFAMILY SSF46955 4 115 5.49E-30 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily AFK25_08105 e50487937df1b34a501b16f1aeb8caaa 128 Gene3D G3DSA:1.10.1660.10 1 124 2.6E-32 T 11-10-2018 AFK25_08105 e50487937df1b34a501b16f1aeb8caaa 128 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 16 29 5.0E-6 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_08105 e50487937df1b34a501b16f1aeb8caaa 128 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 5 16 5.0E-6 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_08105 e50487937df1b34a501b16f1aeb8caaa 128 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 5.0E-6 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_07080 b2add3f1a25514bcb365084e3f346ef5 258 Gene3D G3DSA:3.40.50.150 68 253 9.9E-39 T 11-10-2018 AFK25_07080 b2add3f1a25514bcb365084e3f346ef5 258 SUPERFAMILY SSF53335 2 256 5.33E-55 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_07080 b2add3f1a25514bcb365084e3f346ef5 258 Pfam PF04445 Putative SAM-dependent methyltransferase 41 229 4.9E-15 T 11-10-2018 IPR007536 Ribosomal RNA small subunit methyltransferase J GO:0008990|GO:0031167 AFK25_02555 e9ef82cc06b292dc3f908a65bd5a7de7 191 Pfam PF01206 Sulfurtransferase TusA 6 74 3.5E-22 T 11-10-2018 IPR001455 TusA-like domain AFK25_02555 e9ef82cc06b292dc3f908a65bd5a7de7 191 Pfam PF00581 Rhodanese-like domain 93 182 2.1E-18 T 11-10-2018 IPR001763 Rhodanese-like domain AFK25_02555 e9ef82cc06b292dc3f908a65bd5a7de7 191 Gene3D G3DSA:3.40.250.10 89 183 4.7E-30 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_02555 e9ef82cc06b292dc3f908a65bd5a7de7 191 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 7 31 - T 11-10-2018 IPR001455 TusA-like domain AFK25_02555 e9ef82cc06b292dc3f908a65bd5a7de7 191 SUPERFAMILY SSF64307 3 74 6.41E-25 T 11-10-2018 IPR036868 TusA-like domain superfamily AFK25_02555 e9ef82cc06b292dc3f908a65bd5a7de7 191 SMART SM00450 91 186 2.1E-24 T 11-10-2018 IPR001763 Rhodanese-like domain AFK25_02555 e9ef82cc06b292dc3f908a65bd5a7de7 191 SUPERFAMILY SSF52821 84 182 1.96E-32 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_02555 e9ef82cc06b292dc3f908a65bd5a7de7 191 Gene3D G3DSA:3.30.110.40 1 76 1.1E-29 T 11-10-2018 IPR036868 TusA-like domain superfamily AFK25_02555 e9ef82cc06b292dc3f908a65bd5a7de7 191 ProSitePatterns PS00380 Rhodanese signature 1. 116 127 - T 11-10-2018 IPR001307 Thiosulphate sulfurtransferase, conserved site GO:0004792 KEGG: 00920+2.8.1.1|MetaCyc: PWY-5350|MetaCyc: PWY-7927|Reactome: R-HSA-1614558 AFK25_04325 5f25837510c8c9caa548c2369f9709ea 576 Pfam PF02310 B12 binding domain 9 122 1.1E-21 T 11-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFK25_04325 5f25837510c8c9caa548c2369f9709ea 576 SMART SM00729 176 389 2.0E-24 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFK25_04325 5f25837510c8c9caa548c2369f9709ea 576 Pfam PF13311 Protein of unknown function (DUF4080) 372 543 4.5E-48 T 11-10-2018 IPR025288 Domain of unknown function DUF4080 AFK25_04325 5f25837510c8c9caa548c2369f9709ea 576 SUPERFAMILY SSF102114 170 380 8.5E-39 T 11-10-2018 AFK25_04325 5f25837510c8c9caa548c2369f9709ea 576 SUPERFAMILY SSF52242 40 131 4.39E-9 T 11-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFK25_04325 5f25837510c8c9caa548c2369f9709ea 576 Gene3D G3DSA:3.80.30.20 174 373 1.5E-19 T 11-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFK25_04325 5f25837510c8c9caa548c2369f9709ea 576 Pfam PF04055 Radical SAM superfamily 180 344 2.0E-15 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFK25_04325 5f25837510c8c9caa548c2369f9709ea 576 Gene3D G3DSA:3.40.50.280 21 142 3.9E-12 T 11-10-2018 AFK25_11330 d45261c9f1d003f42d5d45570c03c239 558 ProSitePatterns PS00455 Putative AMP-binding domain signature. 210 221 - T 11-10-2018 IPR020845 AMP-binding, conserved site AFK25_11330 d45261c9f1d003f42d5d45570c03c239 558 SUPERFAMILY SSF56801 9 553 5.49E-163 T 11-10-2018 AFK25_11330 d45261c9f1d003f42d5d45570c03c239 558 Gene3D G3DSA:3.40.50.12780 11 450 1.1E-132 T 11-10-2018 AFK25_11330 d45261c9f1d003f42d5d45570c03c239 558 Pfam PF13193 AMP-binding enzyme C-terminal domain 468 543 2.7E-22 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFK25_11330 d45261c9f1d003f42d5d45570c03c239 558 Gene3D G3DSA:3.30.300.310 455 558 2.8E-35 T 11-10-2018 AFK25_11330 d45261c9f1d003f42d5d45570c03c239 558 Pfam PF00501 AMP-binding enzyme 28 459 9.9E-116 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFK25_14075 a0484eac200922109fd1f701c0bee762 62 SUPERFAMILY SSF55331 2 60 1.16E-20 T 11-10-2018 IPR014347 Tautomerase/MIF superfamily AFK25_14075 a0484eac200922109fd1f701c0bee762 62 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 60 5.9E-30 T 11-10-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 AFK25_14075 a0484eac200922109fd1f701c0bee762 62 Gene3D G3DSA:3.30.429.10 1 60 3.7E-28 T 11-10-2018 IPR014347 Tautomerase/MIF superfamily AFK25_14075 a0484eac200922109fd1f701c0bee762 62 Pfam PF01361 Tautomerase enzyme 2 60 5.4E-25 T 11-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 AFK25_07860 ddb4b53cb28721ca2b13f3cecca6019a 437 ProSitePatterns PS01219 Ammonium transporters signature. 163 188 - T 11-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 AFK25_07860 ddb4b53cb28721ca2b13f3cecca6019a 437 Gene3D G3DSA:1.10.3430.10 2 433 1.2E-132 T 11-10-2018 IPR029020 Ammonium/urea transporter AFK25_07860 ddb4b53cb28721ca2b13f3cecca6019a 437 TIGRFAM TIGR00836 amt: ammonium transporter 11 417 2.9E-121 T 11-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 AFK25_07860 ddb4b53cb28721ca2b13f3cecca6019a 437 Pfam PF00909 Ammonium Transporter Family 13 417 3.3E-110 T 11-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 AFK25_07860 ddb4b53cb28721ca2b13f3cecca6019a 437 SUPERFAMILY SSF111352 10 398 1.57E-107 T 11-10-2018 AFK25_08700 9fab047cf52fe5e7d2b141f9c9f24684 199 Gene3D G3DSA:3.40.1350.10 33 199 7.7E-70 T 11-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 AFK25_08700 9fab047cf52fe5e7d2b141f9c9f24684 199 Hamap MF_00130 Holliday junction resolvase RecU [recU]. 1 199 103.545 T 11-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 AFK25_08700 9fab047cf52fe5e7d2b141f9c9f24684 199 SUPERFAMILY SSF52980 32 198 1.29E-69 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFK25_08700 9fab047cf52fe5e7d2b141f9c9f24684 199 TIGRFAM TIGR00648 recU: recombination protein U 29 197 1.1E-80 T 11-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 AFK25_08700 9fab047cf52fe5e7d2b141f9c9f24684 199 PIRSF PIRSF037785 22 199 3.8E-79 T 11-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 AFK25_08700 9fab047cf52fe5e7d2b141f9c9f24684 199 Pfam PF03838 Recombination protein U 30 195 8.4E-68 T 11-10-2018 IPR004612 Holliday junction resolvase RecU GO:0005737|GO:0006281|GO:0006310 AFK25_12160 a2f7bbe281d4b6591720c67a79223761 256 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_12160 a2f7bbe281d4b6591720c67a79223761 256 SUPERFAMILY SSF52540 4 212 2.46E-62 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_12160 a2f7bbe281d4b6591720c67a79223761 256 Gene3D G3DSA:3.40.50.300 2 241 1.3E-61 T 11-10-2018 AFK25_12160 a2f7bbe281d4b6591720c67a79223761 256 Pfam PF00005 ABC transporter 23 162 7.8E-34 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_12160 a2f7bbe281d4b6591720c67a79223761 256 SMART SM00382 32 211 7.1E-17 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_00080 c6f2c45f21bb1a55f6bb66c5468f0623 294 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 9 294 3.1E-157 T 11-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFK25_00080 c6f2c45f21bb1a55f6bb66c5468f0623 294 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 4 294 54.791 T 11-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFK25_00080 c6f2c45f21bb1a55f6bb66c5468f0623 294 PIRSF PIRSF029271 2 294 9.5E-155 T 11-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFK25_00080 c6f2c45f21bb1a55f6bb66c5468f0623 294 ProSitePatterns PS01235 PdxS/SNZ family signature. 205 223 - T 11-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFK25_00080 c6f2c45f21bb1a55f6bb66c5468f0623 294 Gene3D G3DSA:3.20.20.70 2 294 8.0E-148 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_00080 c6f2c45f21bb1a55f6bb66c5468f0623 294 SUPERFAMILY SSF51366 18 267 5.65E-70 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFK25_00080 c6f2c45f21bb1a55f6bb66c5468f0623 294 Pfam PF01680 SOR/SNZ family 7 212 3.7E-107 T 11-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AFK25_13970 06b3294e5c8c763b6434bf68bdb47e3f 286 Gene3D G3DSA:3.20.20.70 1 286 4.8E-120 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_13970 06b3294e5c8c763b6434bf68bdb47e3f 286 Pfam PF01116 Fructose-bisphosphate aldolase class-II 4 284 7.2E-109 T 11-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFK25_13970 06b3294e5c8c763b6434bf68bdb47e3f 286 PIRSF PIRSF001359 1 285 5.2E-130 T 11-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFK25_13970 06b3294e5c8c763b6434bf68bdb47e3f 286 SUPERFAMILY SSF51569 1 285 2.05E-109 T 11-10-2018 AFK25_13970 06b3294e5c8c763b6434bf68bdb47e3f 286 ProSitePatterns PS00602 Fructose-bisphosphate aldolase class-II signature 1. 74 87 - T 11-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFK25_13970 06b3294e5c8c763b6434bf68bdb47e3f 286 TIGRFAM TIGR00167 cbbA: ketose-bisphosphate aldolase 1 285 1.8E-116 T 11-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFK25_13970 06b3294e5c8c763b6434bf68bdb47e3f 286 ProSitePatterns PS00806 Fructose-bisphosphate aldolase class-II signature 2. 134 145 - T 11-10-2018 IPR000771 Fructose-bisphosphate aldolase, class-II GO:0005975|GO:0008270|GO:0016832 AFK25_13970 06b3294e5c8c763b6434bf68bdb47e3f 286 TIGRFAM TIGR01859 fruc_bis_ald_: fructose-1,6-bisphosphate aldolase, class II 3 285 2.6E-134 T 11-10-2018 IPR011289 Fructose-1,6-bisphosphate aldolase, class 2 GO:0004332|GO:0006096|GO:0008270|GO:0030388 KEGG: 00010+4.1.2.13|KEGG: 00030+4.1.2.13|KEGG: 00051+4.1.2.13|KEGG: 00680+4.1.2.13|KEGG: 00710+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 AFK25_08145 0199c30e21e785cbf75e74e477877dd4 413 SUPERFAMILY SSF53720 8 412 4.32E-113 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFK25_08145 0199c30e21e785cbf75e74e477877dd4 413 TIGRFAM TIGR00407 proA: glutamate-5-semialdehyde dehydrogenase 12 402 2.2E-166 T 11-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFK25_08145 0199c30e21e785cbf75e74e477877dd4 413 Pfam PF00171 Aldehyde dehydrogenase family 70 291 1.1E-11 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFK25_08145 0199c30e21e785cbf75e74e477877dd4 413 Hamap MF_00412 Gamma-glutamyl phosphate reductase [proA]. 3 412 41.48 T 11-10-2018 IPR000965 GPR domain GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFK25_08145 0199c30e21e785cbf75e74e477877dd4 413 Gene3D G3DSA:3.40.309.10 224 370 2.7E-164 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFK25_08145 0199c30e21e785cbf75e74e477877dd4 413 PIRSF PIRSF000151 1 413 6.9E-177 T 11-10-2018 IPR012134 Glutamate-5-semialdehyde dehydrogenase GO:0004350|GO:0006561|GO:0050661|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922 AFK25_08145 0199c30e21e785cbf75e74e477877dd4 413 ProSitePatterns PS01223 Gamma-glutamyl phosphate reductase signature. 319 341 - T 11-10-2018 IPR020593 Gamma-glutamyl phosphate reductase GPR, conserved site GO:0004350|GO:0006561|GO:0055114 KEGG: 00330+1.2.1.41|KEGG: 00332+1.2.1.41|MetaCyc: PWY-3341|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFK25_08145 0199c30e21e785cbf75e74e477877dd4 413 Gene3D G3DSA:3.40.605.10 16 407 2.7E-164 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFK25_06400 a77b9cd21423610034054b34c7238c08 120 SUPERFAMILY SSF54593 1 118 5.09E-22 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFK25_06400 a77b9cd21423610034054b34c7238c08 120 Gene3D G3DSA:3.10.180.10 1 119 1.5E-32 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFK25_06400 a77b9cd21423610034054b34c7238c08 120 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 4 117 1.1E-13 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFK25_07265 78887c0dd922cd691239aa3a522093dd 124 PIRSF PIRSF021424 1 123 4.0E-66 T 11-10-2018 IPR003432 Replication terminator protein GO:0003677|GO:0006274 AFK25_07265 78887c0dd922cd691239aa3a522093dd 124 Pfam PF02334 Replication terminator protein 2 123 8.1E-52 T 11-10-2018 IPR003432 Replication terminator protein GO:0003677|GO:0006274 AFK25_07265 78887c0dd922cd691239aa3a522093dd 124 ProDom PD077583 REPLICATION TRANSCRIPTION DNA-BINDING TERMINATOR REGULATION TERMINATION 3D-STRUCTURE 10 123 7.0E-53 T 11-10-2018 IPR003432 Replication terminator protein GO:0003677|GO:0006274 AFK25_07265 78887c0dd922cd691239aa3a522093dd 124 Gene3D G3DSA:1.10.10.10 1 123 4.4E-45 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_07265 78887c0dd922cd691239aa3a522093dd 124 SUPERFAMILY SSF46785 6 107 2.04E-22 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_01745 6d9a15170cd256f82ac708a04b068c8d 235 Pfam PF01507 Phosphoadenosine phosphosulfate reductase family 40 210 1.0E-50 T 11-10-2018 IPR002500 Phosphoadenosine phosphosulphate reductase GO:0003824 Reactome: R-HSA-196843 AFK25_01745 6d9a15170cd256f82ac708a04b068c8d 235 Hamap MF_00063 Phosphoadenosine phosphosulfate reductase [cysH]. 1 234 40.551 T 11-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 AFK25_01745 6d9a15170cd256f82ac708a04b068c8d 235 Gene3D G3DSA:3.40.50.620 8 235 1.4E-74 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_01745 6d9a15170cd256f82ac708a04b068c8d 235 SUPERFAMILY SSF52402 15 198 3.63E-51 T 11-10-2018 AFK25_01745 6d9a15170cd256f82ac708a04b068c8d 235 PIRSF PIRSF000857 5 235 3.3E-87 T 11-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 AFK25_01745 6d9a15170cd256f82ac708a04b068c8d 235 TIGRFAM TIGR00434 cysH: phosophoadenylyl-sulfate reductase 25 234 3.2E-91 T 11-10-2018 IPR004511 Phosphoadenosine phosphosulphate/adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019379|GO:0055114 KEGG: 00920+1.8.4.8 AFK25_01745 6d9a15170cd256f82ac708a04b068c8d 235 TIGRFAM TIGR02055 APS_reductase: adenylylsulfate reductase, thioredoxin dependent 44 232 4.2E-73 T 11-10-2018 IPR011798 Adenosine 5'-phosphosulphate reductase GO:0004604|GO:0019344|GO:0055114 KEGG: 00920+1.8.4.8 AFK25_10520 9c6f08365b387d8a0f80f255dea06586 251 Pfam PF00691 OmpA family 138 238 3.0E-17 T 11-10-2018 IPR006665 OmpA-like domain AFK25_10520 9c6f08365b387d8a0f80f255dea06586 251 Pfam PF13677 Membrane MotB of proton-channel complex MotA/MotB 3 56 4.9E-22 T 11-10-2018 IPR025713 Motility protein B, N-terminal domain AFK25_10520 9c6f08365b387d8a0f80f255dea06586 251 SUPERFAMILY SSF103088 125 246 7.72E-32 T 11-10-2018 IPR036737 OmpA-like domain superfamily AFK25_10520 9c6f08365b387d8a0f80f255dea06586 251 Gene3D G3DSA:3.30.1330.60 87 250 3.8E-51 T 11-10-2018 IPR036737 OmpA-like domain superfamily AFK25_00120 68f6605948d92f64f0fff52e25b3c5cf 559 Pfam PF12169 DNA polymerase III subunits gamma and tau domain III 234 359 4.7E-16 T 11-10-2018 IPR022754 DNA polymerase III, gamma subunit, domain III GO:0003887 AFK25_00120 68f6605948d92f64f0fff52e25b3c5cf 559 Gene3D G3DSA:1.20.272.10 242 360 2.2E-7 T 11-10-2018 AFK25_00120 68f6605948d92f64f0fff52e25b3c5cf 559 Gene3D G3DSA:3.40.50.300 13 177 1.1E-108 T 11-10-2018 AFK25_00120 68f6605948d92f64f0fff52e25b3c5cf 559 SMART SM00382 37 179 2.3E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_00120 68f6605948d92f64f0fff52e25b3c5cf 559 SUPERFAMILY SSF48019 244 361 2.72E-24 T 11-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 AFK25_00120 68f6605948d92f64f0fff52e25b3c5cf 559 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 41 59 1.0E-5 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_00120 68f6605948d92f64f0fff52e25b3c5cf 559 PRINTS PR00300 ATP-dependent Clp protease ATP-binding subunit signature 124 142 1.0E-5 T 11-10-2018 IPR001270 ClpA/B family GO:0005524 AFK25_00120 68f6605948d92f64f0fff52e25b3c5cf 559 Pfam PF13177 DNA polymerase III, delta subunit 20 178 2.1E-46 T 11-10-2018 AFK25_00120 68f6605948d92f64f0fff52e25b3c5cf 559 SUPERFAMILY SSF52540 31 224 9.93E-61 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_00120 68f6605948d92f64f0fff52e25b3c5cf 559 Gene3D G3DSA:1.10.8.60 8 238 1.1E-108 T 11-10-2018 AFK25_00120 68f6605948d92f64f0fff52e25b3c5cf 559 TIGRFAM TIGR02397 dnaX_nterm: DNA polymerase III, subunit gamma and tau 3 358 2.7E-146 T 11-10-2018 IPR012763 DNA polymerase III, subunit gamma/ tau GO:0003887|GO:0005524|GO:0006260|GO:0009360 AFK25_10915 e82e118c64053a520d2b79fe66981acc 181 SUPERFAMILY SSF55890 1 166 1.01E-45 T 11-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 AFK25_10915 e82e118c64053a520d2b79fe66981acc 181 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 6 57 2.2E-20 T 11-10-2018 IPR039506 SpoOB, alpha-helical domain AFK25_10915 e82e118c64053a520d2b79fe66981acc 181 SMART SM01317 59 173 1.8E-57 T 11-10-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal AFK25_10915 e82e118c64053a520d2b79fe66981acc 181 Gene3D G3DSA:3.30.565.30 58 175 5.1E-37 T 11-10-2018 IPR037100 Sporulation initiation phosphotransferase B, C-terminal domain superfamily AFK25_10915 e82e118c64053a520d2b79fe66981acc 181 Pfam PF14682 Sporulation initiation phospho-transferase B, C-terminal 61 171 3.6E-39 T 11-10-2018 IPR016122 Sporulation initiation phosphotransferase B, C-terminal AFK25_10915 e82e118c64053a520d2b79fe66981acc 181 Gene3D G3DSA:1.10.287.130 1 57 1.8E-23 T 11-10-2018 AFK25_12860 c175a1021f4152a78d450a5ac8693269 154 Hamap MF_00023 SsrA-binding protein [smpB]. 1 154 80.529 T 11-10-2018 IPR000037 SsrA-binding protein GO:0003723 AFK25_12860 c175a1021f4152a78d450a5ac8693269 154 Gene3D G3DSA:2.40.280.10 3 129 8.8E-54 T 11-10-2018 IPR023620 Small protein B AFK25_12860 c175a1021f4152a78d450a5ac8693269 154 ProSitePatterns PS01317 SsrA-binding protein. 27 39 - T 11-10-2018 IPR020081 SsrA-binding protein, conserved site AFK25_12860 c175a1021f4152a78d450a5ac8693269 154 TIGRFAM TIGR00086 smpB: SsrA-binding protein 9 149 3.0E-61 T 11-10-2018 IPR000037 SsrA-binding protein GO:0003723 AFK25_12860 c175a1021f4152a78d450a5ac8693269 154 SUPERFAMILY SSF74982 4 132 8.63E-56 T 11-10-2018 IPR023620 Small protein B AFK25_12860 c175a1021f4152a78d450a5ac8693269 154 Pfam PF01668 SmpB protein 9 150 3.3E-65 T 11-10-2018 IPR000037 SsrA-binding protein GO:0003723 AFK25_12860 c175a1021f4152a78d450a5ac8693269 154 ProDom PD004488 SSRA-BINDING RNA-BINDING SMPB SMALL B TMRNA-BINDING SSRA 3D-STRUCTURE HOMOLOG BINDING 9 117 2.0E-57 T 11-10-2018 IPR000037 SsrA-binding protein GO:0003723 AFK25_07720 2c21b00ed4ebb1e3d93a94556386b4b8 642 Gene3D G3DSA:3.40.50.300 35 307 1.0E-29 T 11-10-2018 AFK25_07720 2c21b00ed4ebb1e3d93a94556386b4b8 642 Gene3D G3DSA:3.40.50.300 461 633 3.3E-27 T 11-10-2018 AFK25_07720 2c21b00ed4ebb1e3d93a94556386b4b8 642 SMART SM00491 501 620 7.6E-7 T 11-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 AFK25_07720 2c21b00ed4ebb1e3d93a94556386b4b8 642 Pfam PF13307 Helicase C-terminal domain 487 618 3.5E-24 T 11-10-2018 IPR006555 ATP-dependent helicase, C-terminal GO:0003676|GO:0005524|GO:0006139|GO:0008026|GO:0016818 AFK25_07720 2c21b00ed4ebb1e3d93a94556386b4b8 642 SUPERFAMILY SSF52540 50 622 1.16E-23 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_05315 22e977557081a7d8206cde275a5fc8bb 917 Pfam PF06827 Zinc finger found in FPG and IleRS 885 912 3.7E-8 T 11-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 AFK25_05315 22e977557081a7d8206cde275a5fc8bb 917 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 519 532 3.8E-32 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFK25_05315 22e977557081a7d8206cde275a5fc8bb 917 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 391 406 3.8E-32 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFK25_05315 22e977557081a7d8206cde275a5fc8bb 917 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 50 61 3.8E-32 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFK25_05315 22e977557081a7d8206cde275a5fc8bb 917 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 553 562 3.8E-32 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFK25_05315 22e977557081a7d8206cde275a5fc8bb 917 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 229 252 3.8E-32 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFK25_05315 22e977557081a7d8206cde275a5fc8bb 917 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 57 68 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_05315 22e977557081a7d8206cde275a5fc8bb 917 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 27 633 1.7E-225 T 11-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_05315 22e977557081a7d8206cde275a5fc8bb 917 SUPERFAMILY SSF52374 1 640 9.47E-158 T 11-10-2018 AFK25_05315 22e977557081a7d8206cde275a5fc8bb 917 Gene3D G3DSA:3.40.50.620 24 621 4.0E-268 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_05315 22e977557081a7d8206cde275a5fc8bb 917 SUPERFAMILY SSF50677 202 393 4.19E-65 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFK25_05315 22e977557081a7d8206cde275a5fc8bb 917 Pfam PF08264 Anticodon-binding domain of tRNA 676 830 2.1E-31 T 11-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AFK25_05315 22e977557081a7d8206cde275a5fc8bb 917 Gene3D G3DSA:3.90.740.10 194 398 4.0E-268 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFK25_05315 22e977557081a7d8206cde275a5fc8bb 917 Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. 1 916 21.298 T 11-10-2018 IPR023585 Isoleucine-tRNA ligase, type 1 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-379726 AFK25_05315 22e977557081a7d8206cde275a5fc8bb 917 Gene3D G3DSA:1.10.730.20 632 917 7.9E-103 T 11-10-2018 AFK25_05315 22e977557081a7d8206cde275a5fc8bb 917 SUPERFAMILY SSF47323 644 916 7.66E-80 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_05315 22e977557081a7d8206cde275a5fc8bb 917 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 14 829 0.0 T 11-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AFK25_03880 8d789f5a598f00f2e125f822421d53e6 384 Pfam PF14657 Arm DNA-binding domain 15 58 1.8E-9 T 11-10-2018 IPR028259 AP2-like integrase, N-terminal domain AFK25_03880 8d789f5a598f00f2e125f822421d53e6 384 Gene3D G3DSA:1.10.443.10 173 374 2.4E-59 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFK25_03880 8d789f5a598f00f2e125f822421d53e6 384 SUPERFAMILY SSF56349 70 368 6.77E-74 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFK25_03880 8d789f5a598f00f2e125f822421d53e6 384 Pfam PF14659 Phage integrase, N-terminal SAM-like domain 68 122 3.0E-12 T 11-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFK25_03880 8d789f5a598f00f2e125f822421d53e6 384 Pfam PF00589 Phage integrase family 176 360 1.2E-29 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFK25_03880 8d789f5a598f00f2e125f822421d53e6 384 Gene3D G3DSA:1.10.150.130 63 172 2.7E-26 T 11-10-2018 IPR010998 Integrase/recombinase, N-terminal AFK25_14150 da68b3caca0ad8c18ffc18141b3c50ba 538 Gene3D G3DSA:3.90.400.10 110 166 3.4E-30 T 11-10-2018 AFK25_14150 da68b3caca0ad8c18ffc18141b3c50ba 538 Gene3D G3DSA:3.20.20.80 1 109 4.2E-47 T 11-10-2018 AFK25_14150 da68b3caca0ad8c18ffc18141b3c50ba 538 SUPERFAMILY SSF51445 3 456 3.75E-151 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily AFK25_14150 da68b3caca0ad8c18ffc18141b3c50ba 538 Gene3D G3DSA:3.20.20.80 167 460 4.3E-113 T 11-10-2018 AFK25_14150 da68b3caca0ad8c18ffc18141b3c50ba 538 Gene3D G3DSA:2.60.40.1180 461 538 2.6E-17 T 11-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFK25_14150 da68b3caca0ad8c18ffc18141b3c50ba 538 SUPERFAMILY SSF51011 460 537 2.61E-15 T 11-10-2018 AFK25_14150 da68b3caca0ad8c18ffc18141b3c50ba 538 SMART SM00642 13 399 1.0E-144 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFK25_14150 da68b3caca0ad8c18ffc18141b3c50ba 538 Pfam PF00128 Alpha amylase, catalytic domain 28 357 1.7E-111 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFK25_06010 65929bda134870a944f7dce4e80251f3 400 Gene3D G3DSA:1.10.10.2840 260 392 6.8E-22 T 11-10-2018 AFK25_06010 65929bda134870a944f7dce4e80251f3 400 SUPERFAMILY SSF46689 330 364 7.17E-5 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_06010 65929bda134870a944f7dce4e80251f3 400 Pfam PF13556 PucR C-terminal helix-turn-helix domain 330 386 8.3E-21 T 11-10-2018 IPR025736 PucR C-terminal helix-turn-helix domain AFK25_04215 62175c290fe005744526da5b0ce0c3a0 187 Gene3D G3DSA:3.40.50.150 2 185 2.4E-48 T 11-10-2018 AFK25_04215 62175c290fe005744526da5b0ce0c3a0 187 Pfam PF08241 Methyltransferase domain 42 136 1.3E-19 T 11-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFK25_04215 62175c290fe005744526da5b0ce0c3a0 187 SUPERFAMILY SSF53335 26 167 3.56E-29 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_12285 45b705a6f350524e5bbc44c7642fd03a 311 Pfam PF01040 UbiA prenyltransferase family 34 264 7.3E-38 T 11-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AFK25_12285 45b705a6f350524e5bbc44c7642fd03a 311 TIGRFAM TIGR00751 menA: 1,4-dihydroxy-2-naphthoate octaprenyltransferase 26 295 1.8E-37 T 11-10-2018 AFK25_12285 45b705a6f350524e5bbc44c7642fd03a 311 Hamap MF_01937 1,4-dihydroxy-2-naphthoate octaprenyltransferase [menA]. 17 304 19.9 T 11-10-2018 IPR004657 1,4-dihydroxy-2-naphthoate octaprenyltransferase GO:0009234|GO:0016021|GO:0046428 KEGG: 00130+2.5.1.74|MetaCyc: PWY-5839|MetaCyc: PWY-5851|MetaCyc: PWY-5852|MetaCyc: PWY-5853|MetaCyc: PWY-5890|MetaCyc: PWY-5891|MetaCyc: PWY-5892|MetaCyc: PWY-5895 AFK25_12285 45b705a6f350524e5bbc44c7642fd03a 311 PIRSF PIRSF005355 10 308 8.9E-89 T 11-10-2018 IPR026046 UbiA prenyltransferase domain containing protein 1 GO:0004659 Reactome: R-HSA-6806664 AFK25_05450 9429ad9da89a4d11c1b49abf81f81c33 293 Pfam PF03193 RsgA GTPase 59 225 2.8E-64 T 11-10-2018 IPR010914 RsgA GTPase domain GO:0003924|GO:0005525 AFK25_05450 9429ad9da89a4d11c1b49abf81f81c33 293 Gene3D G3DSA:3.40.50.300 62 225 2.8E-51 T 11-10-2018 AFK25_05450 9429ad9da89a4d11c1b49abf81f81c33 293 SUPERFAMILY SSF52540 64 291 1.69E-64 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_05450 9429ad9da89a4d11c1b49abf81f81c33 293 SUPERFAMILY SSF50249 1 63 1.2E-16 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_05450 9429ad9da89a4d11c1b49abf81f81c33 293 Pfam PF16745 RsgA N-terminal domain 3 56 9.3E-26 T 11-10-2018 IPR031944 Ribosome biogenesis GTPase RsgA, N-terminal AFK25_05450 9429ad9da89a4d11c1b49abf81f81c33 293 Hamap MF_01820 Small ribosomal subunit biogenesis GTPase RsgA [rsgA]. 2 290 40.497 T 11-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 AFK25_05450 9429ad9da89a4d11c1b49abf81f81c33 293 Gene3D G3DSA:1.10.40.50 227 293 1.0E-22 T 11-10-2018 AFK25_05450 9429ad9da89a4d11c1b49abf81f81c33 293 TIGRFAM TIGR00157 TIGR00157: ribosome small subunit-dependent GTPase A 39 284 2.3E-88 T 11-10-2018 IPR004881 Ribosome biogenesis GTPase RsgA GO:0003924|GO:0005525 AFK25_05450 9429ad9da89a4d11c1b49abf81f81c33 293 Gene3D G3DSA:2.40.50.140 1 61 2.3E-26 T 11-10-2018 AFK25_12460 e8b9d1219417561eda77984c9549b584 207 SMART SM00471 20 155 2.3E-12 T 11-10-2018 IPR003607 HD/PDEase domain AFK25_12460 e8b9d1219417561eda77984c9549b584 207 TIGRFAM TIGR00277 HDIG: HDIG domain 23 114 3.0E-9 T 11-10-2018 IPR006675 HDIG domain AFK25_12460 e8b9d1219417561eda77984c9549b584 207 Gene3D G3DSA:1.10.3210.10 10 193 1.1E-62 T 11-10-2018 AFK25_12460 e8b9d1219417561eda77984c9549b584 207 Pfam PF01966 HD domain 25 146 3.0E-21 T 11-10-2018 IPR006674 HD domain AFK25_12460 e8b9d1219417561eda77984c9549b584 207 SUPERFAMILY SSF109604 13 185 5.73E-37 T 11-10-2018 AFK25_14065 70effdc95b8afc65e18c5af03b0dd15a 168 Pfam PF08741 YwhD family 4 164 1.8E-83 T 11-10-2018 IPR014852 Uncharacterised protein YwhD AFK25_07375 b1266df2c39a721fd507d6a1be6d8815 117 Gene3D G3DSA:3.40.1260.10 1 110 5.4E-8 T 11-10-2018 IPR027396 DsrEFH-like AFK25_07375 b1266df2c39a721fd507d6a1be6d8815 117 SUPERFAMILY SSF75169 1 115 3.53E-16 T 11-10-2018 IPR027396 DsrEFH-like AFK25_07375 b1266df2c39a721fd507d6a1be6d8815 117 Pfam PF02635 DsrE/DsrF-like family 2 115 2.3E-13 T 11-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein AFK25_07375 b1266df2c39a721fd507d6a1be6d8815 117 ProDom PD052877 ARCHAEL AF0269 2 44 0.006 T 11-10-2018 AFK25_06685 3657c53071bfce20001fad5723e857ae 306 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 8 292 3.5E-66 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFK25_06685 3657c53071bfce20001fad5723e857ae 306 Gene3D G3DSA:3.40.50.1100 8 299 7.4E-118 T 11-10-2018 AFK25_06685 3657c53071bfce20001fad5723e857ae 306 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 32 50 - T 11-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 AFK25_06685 3657c53071bfce20001fad5723e857ae 306 Gene3D G3DSA:3.40.50.1100 44 146 7.4E-118 T 11-10-2018 AFK25_06685 3657c53071bfce20001fad5723e857ae 306 TIGRFAM TIGR01136 cysKM: cysteine synthase 7 304 3.2E-120 T 11-10-2018 IPR005856 Cysteine synthase GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 AFK25_06685 3657c53071bfce20001fad5723e857ae 306 TIGRFAM TIGR01139 cysK: cysteine synthase A 8 304 1.9E-125 T 11-10-2018 IPR005859 Cysteine synthase CysK GO:0004124|GO:0006535 KEGG: 00270+2.5.1.47|KEGG: 00920+2.5.1.47|MetaCyc: PWY-6936 AFK25_06685 3657c53071bfce20001fad5723e857ae 306 SUPERFAMILY SSF53686 2 303 1.03E-97 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFK25_03580 210b219184b083d394ad197b4917a089 440 SMART SM00924 20 125 6.3E-21 T 11-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain AFK25_03580 210b219184b083d394ad197b4917a089 440 TIGRFAM TIGR00400 mgtE: magnesium transporter 5 437 6.7E-130 T 11-10-2018 IPR006669 Magnesium transporter MgtE GO:0015095|GO:0015693|GO:0016020 AFK25_03580 210b219184b083d394ad197b4917a089 440 Gene3D G3DSA:1.10.357.20 260 437 1.7E-61 T 11-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain AFK25_03580 210b219184b083d394ad197b4917a089 440 SUPERFAMILY SSF54631 124 260 1.77E-35 T 11-10-2018 AFK25_03580 210b219184b083d394ad197b4917a089 440 Pfam PF03448 MgtE intracellular N domain 20 122 6.3E-20 T 11-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain AFK25_03580 210b219184b083d394ad197b4917a089 440 SUPERFAMILY SSF161093 266 436 8.89E-54 T 11-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 AFK25_03580 210b219184b083d394ad197b4917a089 440 SMART SM00116 196 244 3.9E-8 T 11-10-2018 IPR000644 CBS domain AFK25_03580 210b219184b083d394ad197b4917a089 440 SMART SM00116 132 185 0.21 T 11-10-2018 IPR000644 CBS domain AFK25_03580 210b219184b083d394ad197b4917a089 440 Gene3D G3DSA:1.25.60.10 1 120 2.7E-40 T 11-10-2018 IPR038076 MgtE, N-terminal domain superfamily AFK25_03580 210b219184b083d394ad197b4917a089 440 Pfam PF01769 Divalent cation transporter 308 429 1.9E-32 T 11-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 AFK25_03580 210b219184b083d394ad197b4917a089 440 Pfam PF00571 CBS domain 125 182 1.1E-8 T 11-10-2018 IPR000644 CBS domain AFK25_03580 210b219184b083d394ad197b4917a089 440 Pfam PF00571 CBS domain 191 244 4.6E-10 T 11-10-2018 IPR000644 CBS domain AFK25_03580 210b219184b083d394ad197b4917a089 440 SUPERFAMILY SSF158791 2 122 1.57E-26 T 11-10-2018 AFK25_03580 210b219184b083d394ad197b4917a089 440 Gene3D G3DSA:3.10.580.10 121 249 7.9E-47 T 11-10-2018 AFK25_13735 e9920f7974ebb9647aab6ef38e39215f 262 TIGRFAM TIGR02490 flgF: flagellar basal-body rod protein FlgF 5 238 1.2E-58 T 11-10-2018 IPR012836 Flagellar basal-body rod FlgF GO:0030694|GO:0071973 AFK25_13735 e9920f7974ebb9647aab6ef38e39215f 262 ProSitePatterns PS00588 Flagella basal body rod proteins signature. 11 31 - T 11-10-2018 IPR019776 Flagellar basal body rod protein, conserved site AFK25_13735 e9920f7974ebb9647aab6ef38e39215f 262 SUPERFAMILY SSF117143 98 219 5.75E-22 T 11-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like AFK25_13735 e9920f7974ebb9647aab6ef38e39215f 262 Pfam PF00460 Flagella basal body rod protein 5 35 6.0E-13 T 11-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 AFK25_13735 e9920f7974ebb9647aab6ef38e39215f 262 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 187 256 1.1E-18 T 11-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain AFK25_13735 e9920f7974ebb9647aab6ef38e39215f 262 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 145 2.9E-38 T 11-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G AFK25_05525 bfb79711f7040ead606250331c25125a 238 SMART SM00358 166 233 1.1E-22 T 11-10-2018 IPR014720 Double-stranded RNA-binding domain AFK25_05525 bfb79711f7040ead606250331c25125a 238 Gene3D G3DSA:1.10.1520.10 9 156 8.2E-48 T 11-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 AFK25_05525 bfb79711f7040ead606250331c25125a 238 Hamap MF_00104 Ribonuclease 3 [rnc]. 13 229 31.886 T 11-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 AFK25_05525 bfb79711f7040ead606250331c25125a 238 Gene3D G3DSA:3.30.160.20 164 237 2.0E-23 T 11-10-2018 AFK25_05525 bfb79711f7040ead606250331c25125a 238 Pfam PF00035 Double-stranded RNA binding motif 166 232 2.1E-18 T 11-10-2018 IPR014720 Double-stranded RNA-binding domain AFK25_05525 bfb79711f7040ead606250331c25125a 238 ProSitePatterns PS00517 Ribonuclease III family signature. 49 57 - T 11-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 AFK25_05525 bfb79711f7040ead606250331c25125a 238 TIGRFAM TIGR02191 RNaseIII: ribonuclease III 13 232 6.6E-81 T 11-10-2018 IPR011907 Ribonuclease III GO:0003723|GO:0004525|GO:0016075 Reactome: R-HSA-203927 AFK25_05525 bfb79711f7040ead606250331c25125a 238 Pfam PF14622 Ribonuclease-III-like 23 154 1.8E-37 T 11-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 AFK25_05525 bfb79711f7040ead606250331c25125a 238 SMART SM00535 25 160 6.2E-59 T 11-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 AFK25_05525 bfb79711f7040ead606250331c25125a 238 SUPERFAMILY SSF54768 120 233 6.44E-26 T 11-10-2018 AFK25_05525 bfb79711f7040ead606250331c25125a 238 SUPERFAMILY SSF69065 7 168 2.44E-52 T 11-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 AFK25_12980 3d90b7c5f48cb451f887adc2be2a89dc 204 Pfam PF01503 Phosphoribosyl-ATP pyrophosphohydrolase 119 203 1.9E-18 T 11-10-2018 IPR021130 Phosphoribosyl-ATP pyrophosphohydrolase-like KEGG: 00340+3.6.1.31 AFK25_12980 3d90b7c5f48cb451f887adc2be2a89dc 204 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 1 102 30.117 T 11-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AFK25_12980 3d90b7c5f48cb451f887adc2be2a89dc 204 TIGRFAM TIGR03188 histidine_hisI: phosphoribosyl-ATP diphosphatase 116 199 3.2E-33 T 11-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 AFK25_12980 3d90b7c5f48cb451f887adc2be2a89dc 204 Hamap MF_01020 Phosphoribosyl-ATP pyrophosphatase [hisE]. 113 199 21.05 T 11-10-2018 IPR008179 Phosphoribosyl-ATP pyrophosphohydrolase GO:0000105|GO:0004636 KEGG: 00340+3.6.1.31 AFK25_12980 3d90b7c5f48cb451f887adc2be2a89dc 204 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 48 97 3.0E-23 T 11-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AFK25_12980 3d90b7c5f48cb451f887adc2be2a89dc 204 SUPERFAMILY SSF101386 116 203 6.73E-27 T 11-10-2018 AFK25_12980 3d90b7c5f48cb451f887adc2be2a89dc 204 Gene3D G3DSA:1.10.287.1080 113 204 2.4E-34 T 11-10-2018 AFK25_12980 3d90b7c5f48cb451f887adc2be2a89dc 204 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 26 98 1.3E-35 T 11-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AFK25_12980 3d90b7c5f48cb451f887adc2be2a89dc 204 Hamap MF_01019 Histidine biosynthesis bifunctional protein HisIE [hisI]. 1 204 39.096 T 11-10-2018 IPR023019 Histidine biosynthesis bifunctional protein HisIE GO:0000105|GO:0004635|GO:0004636 KEGG: 00340+3.6.1.31+3.5.4.19 AFK25_12980 3d90b7c5f48cb451f887adc2be2a89dc 204 Gene3D G3DSA:3.10.20.400 1 89 9.7E-42 T 11-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 AFK25_12980 3d90b7c5f48cb451f887adc2be2a89dc 204 SUPERFAMILY SSF141734 3 105 1.1E-48 T 11-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 AFK25_11510 b3490c8ba8b7dff41222e51a4b7f067a 162 Pfam PF08761 dUTPase 2 162 1.3E-49 T 11-10-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 AFK25_11510 b3490c8ba8b7dff41222e51a4b7f067a 162 Gene3D G3DSA:1.10.4010.10 1 162 1.1E-14 T 11-10-2018 AFK25_11510 b3490c8ba8b7dff41222e51a4b7f067a 162 SUPERFAMILY SSF101386 2 162 3.14E-42 T 11-10-2018 AFK25_11510 b3490c8ba8b7dff41222e51a4b7f067a 162 PIRSF PIRSF030140 1 162 1.9E-54 T 11-10-2018 IPR016947 Uncharacterised phage-associated protein UCP030140 AFK25_11240 f837ce2ee579fb1d8904dbd3d0330c0e 253 Pfam PF13183 4Fe-4S dicluster domain 151 226 4.8E-9 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFK25_11240 f837ce2ee579fb1d8904dbd3d0330c0e 253 Gene3D G3DSA:3.10.20.30 1 112 6.4E-31 T 11-10-2018 IPR012675 Beta-grasp domain superfamily AFK25_11240 f837ce2ee579fb1d8904dbd3d0330c0e 253 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 10 117 6.3E-29 T 11-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFK25_11240 f837ce2ee579fb1d8904dbd3d0330c0e 253 Gene3D G3DSA:1.10.1060.10 114 249 1.2E-28 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFK25_11240 f837ce2ee579fb1d8904dbd3d0330c0e 253 SUPERFAMILY SSF46548 114 239 7.32E-27 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFK25_11240 f837ce2ee579fb1d8904dbd3d0330c0e 253 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 12 234 1.4E-40 T 11-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFK25_11240 f837ce2ee579fb1d8904dbd3d0330c0e 253 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 155 166 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFK25_11240 f837ce2ee579fb1d8904dbd3d0330c0e 253 SUPERFAMILY SSF54292 5 112 1.67E-23 T 11-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AFK25_03160 63559aac1801082016f84dc5925fac58 360 Gene3D G3DSA:3.90.550.10 25 256 2.5E-30 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_03160 63559aac1801082016f84dc5925fac58 360 Pfam PF13641 Glycosyltransferase like family 2 34 262 2.4E-20 T 11-10-2018 AFK25_03160 63559aac1801082016f84dc5925fac58 360 SUPERFAMILY SSF53448 27 292 9.38E-39 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_08650 a71b073120f4938d82e6a64e81a531d7 363 Pfam PF07694 5TMR of 5TMR-LYT 23 175 8.9E-19 T 11-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 AFK25_08650 a71b073120f4938d82e6a64e81a531d7 363 SUPERFAMILY SSF55073 200 357 7.85E-46 T 11-10-2018 IPR029787 Nucleotide cyclase AFK25_08650 a71b073120f4938d82e6a64e81a531d7 363 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 193 354 1.2E-45 T 11-10-2018 IPR000160 GGDEF domain AFK25_08650 a71b073120f4938d82e6a64e81a531d7 363 SMART SM00267 181 355 4.3E-52 T 11-10-2018 IPR000160 GGDEF domain AFK25_08650 a71b073120f4938d82e6a64e81a531d7 363 Gene3D G3DSA:3.30.70.270 192 362 5.2E-52 T 11-10-2018 AFK25_08650 a71b073120f4938d82e6a64e81a531d7 363 Gene3D G3DSA:1.10.1760.20 35 191 7.2E-6 T 11-10-2018 AFK25_08650 a71b073120f4938d82e6a64e81a531d7 363 Pfam PF00990 Diguanylate cyclase, GGDEF domain 195 351 9.2E-44 T 11-10-2018 IPR000160 GGDEF domain AFK25_13905 08c7cb54d61b18dc92354e479fc24283 430 SUPERFAMILY SSF58104 101 428 4.32E-70 T 11-10-2018 AFK25_13905 08c7cb54d61b18dc92354e479fc24283 430 Gene3D G3DSA:1.10.287.950 123 429 1.6E-65 T 11-10-2018 AFK25_13905 08c7cb54d61b18dc92354e479fc24283 430 Pfam PF00672 HAMP domain 72 122 3.2E-12 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_13905 08c7cb54d61b18dc92354e479fc24283 430 SMART SM00304 72 125 3.6E-13 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_13905 08c7cb54d61b18dc92354e479fc24283 430 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 223 382 2.1E-38 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_13905 08c7cb54d61b18dc92354e479fc24283 430 Gene3D G3DSA:1.10.8.500 71 122 7.4E-10 T 11-10-2018 AFK25_13905 08c7cb54d61b18dc92354e479fc24283 430 SMART SM00283 154 429 1.3E-59 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_01025 a03d7a8aa01a9d46146a828901feafb1 296 Gene3D G3DSA:3.20.20.70 1 296 4.0E-130 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_01025 a03d7a8aa01a9d46146a828901feafb1 296 Pfam PF00682 HMGL-like 3 275 1.9E-48 T 11-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AFK25_01025 a03d7a8aa01a9d46146a828901feafb1 296 SUPERFAMILY SSF51569 2 289 9.16E-74 T 11-10-2018 AFK25_01940 055fc9442dfd67d2aa7044b82f0193ce 534 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 84 453 1.1E-116 T 11-10-2018 IPR000914 Solute-binding protein family 5 domain AFK25_01940 055fc9442dfd67d2aa7044b82f0193ce 534 PIRSF PIRSF002741 1 534 5.2E-148 T 11-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 AFK25_01940 055fc9442dfd67d2aa7044b82f0193ce 534 SUPERFAMILY SSF53850 36 531 4.29E-160 T 11-10-2018 AFK25_01940 055fc9442dfd67d2aa7044b82f0193ce 534 ProSitePatterns PS01040 Bacterial extracellular solute-binding proteins, family 5 signature. 90 112 - T 11-10-2018 IPR023765 Solute-binding protein family 5, conserved site AFK25_01940 055fc9442dfd67d2aa7044b82f0193ce 534 Gene3D G3DSA:3.90.76.10 56 209 1.4E-178 T 11-10-2018 AFK25_01940 055fc9442dfd67d2aa7044b82f0193ce 534 Gene3D G3DSA:3.40.190.10 210 522 1.4E-178 T 11-10-2018 AFK25_01940 055fc9442dfd67d2aa7044b82f0193ce 534 Gene3D G3DSA:3.10.105.10 292 509 1.4E-178 T 11-10-2018 AFK25_13665 e5e969acbdeb62375d90580be0cf37e7 511 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 257 452 1.6E-38 T 11-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 AFK25_13665 e5e969acbdeb62375d90580be0cf37e7 511 Gene3D G3DSA:3.30.420.40 251 511 9.8E-89 T 11-10-2018 AFK25_13665 e5e969acbdeb62375d90580be0cf37e7 511 Gene3D G3DSA:3.30.420.40 2 249 4.9E-83 T 11-10-2018 AFK25_13665 e5e969acbdeb62375d90580be0cf37e7 511 SUPERFAMILY SSF53067 4 251 9.08E-72 T 11-10-2018 AFK25_13665 e5e969acbdeb62375d90580be0cf37e7 511 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 365 385 - T 11-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFK25_13665 e5e969acbdeb62375d90580be0cf37e7 511 PIRSF PIRSF000538 2 503 1.1E-151 T 11-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFK25_13665 e5e969acbdeb62375d90580be0cf37e7 511 SUPERFAMILY SSF53067 251 498 3.67E-67 T 11-10-2018 AFK25_13665 e5e969acbdeb62375d90580be0cf37e7 511 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 248 2.6E-71 T 11-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 AFK25_02205 25b5f474bdc622c5939930aba215e895 285 Gene3D G3DSA:3.90.1720.10 124 277 2.5E-5 T 11-10-2018 AFK25_02205 25b5f474bdc622c5939930aba215e895 285 Pfam PF12671 Putative amidase domain 126 278 2.8E-41 T 11-10-2018 IPR024301 Putative amidase domain AFK25_04085 352ff653d47a0904161cbb2367fa7a7b 280 PIRSF PIRSF002854 1 274 3.6E-84 T 11-10-2018 IPR004872 Lipoprotein NlpA family AFK25_04085 352ff653d47a0904161cbb2367fa7a7b 280 Pfam PF03180 NLPA lipoprotein 38 274 2.2E-80 T 11-10-2018 IPR004872 Lipoprotein NlpA family AFK25_04085 352ff653d47a0904161cbb2367fa7a7b 280 SUPERFAMILY SSF53850 37 277 2.27E-75 T 11-10-2018 AFK25_04085 352ff653d47a0904161cbb2367fa7a7b 280 Gene3D G3DSA:3.40.190.10 38 268 5.1E-87 T 11-10-2018 AFK25_04085 352ff653d47a0904161cbb2367fa7a7b 280 Gene3D G3DSA:3.40.190.10 120 224 5.1E-87 T 11-10-2018 AFK25_09430 8fe25afef8f9c337a9cde5ca4e1c9c91 274 SUPERFAMILY SSF53167 5 272 1.2E-102 T 11-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 AFK25_09430 8fe25afef8f9c337a9cde5ca4e1c9c91 274 ProSitePatterns PS01240 Purine and other phosphorylases family 2 signature. 75 116 - T 11-10-2018 IPR018099 Purine phosphorylase, family 2, conserved site GO:0016763 AFK25_09430 8fe25afef8f9c337a9cde5ca4e1c9c91 274 TIGRFAM TIGR01697 PNPH-PUNA-XAPA: inosine/guanosine/xanthosine phosphorylase family 22 268 5.1E-112 T 11-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 AFK25_09430 8fe25afef8f9c337a9cde5ca4e1c9c91 274 PIRSF PIRSF000477 1 271 1.7E-120 T 11-10-2018 IPR011268 Purine nucleoside phosphorylase GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 AFK25_09430 8fe25afef8f9c337a9cde5ca4e1c9c91 274 Gene3D G3DSA:3.40.50.1580 1 273 1.4E-117 T 11-10-2018 AFK25_09430 8fe25afef8f9c337a9cde5ca4e1c9c91 274 Pfam PF01048 Phosphorylase superfamily 23 269 2.1E-56 T 11-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 AFK25_09430 8fe25afef8f9c337a9cde5ca4e1c9c91 274 TIGRFAM TIGR01700 PNPH: purine nucleoside phosphorylase I, inosine and guanosine-specific 22 268 2.6E-118 T 11-10-2018 IPR011270 Purine nucleoside phosphorylase I, inosine/guanosine-specific GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-6798695|Reactome: R-HSA-74217|Reactome: R-HSA-74259 AFK25_10140 46e866e191ef181581155a2137a8b5de 219 Gene3D G3DSA:1.20.58.220 3 219 2.3E-75 T 11-10-2018 IPR038078 PhoU-like domain superfamily AFK25_10140 46e866e191ef181581155a2137a8b5de 219 Pfam PF01895 PhoU domain 18 105 7.3E-19 T 11-10-2018 IPR026022 PhoU domain AFK25_10140 46e866e191ef181581155a2137a8b5de 219 Pfam PF01895 PhoU domain 121 205 1.9E-21 T 11-10-2018 IPR026022 PhoU domain AFK25_10140 46e866e191ef181581155a2137a8b5de 219 SUPERFAMILY SSF109755 4 218 7.95E-67 T 11-10-2018 AFK25_10140 46e866e191ef181581155a2137a8b5de 219 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 6 214 6.3E-65 T 11-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 AFK25_10140 46e866e191ef181581155a2137a8b5de 219 PIRSF PIRSF003107 1 219 4.8E-63 T 11-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 AFK25_05425 2db02869e5355290a8b6eba225215f2f 314 Pfam PF02911 Formyl transferase, C-terminal domain 203 301 7.3E-31 T 11-10-2018 IPR005793 Formyl transferase, C-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFK25_05425 2db02869e5355290a8b6eba225215f2f 314 ProSitePatterns PS00373 Phosphoribosylglycinamide formyltransferase active site. 132 155 - T 11-10-2018 IPR001555 Phosphoribosylglycinamide formyltransferase, active site KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFK25_05425 2db02869e5355290a8b6eba225215f2f 314 SUPERFAMILY SSF53328 1 205 4.19E-70 T 11-10-2018 IPR036477 Formyl transferase, N-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFK25_05425 2db02869e5355290a8b6eba225215f2f 314 TIGRFAM TIGR00460 fmt: methionyl-tRNA formyltransferase 1 306 4.1E-114 T 11-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 AFK25_05425 2db02869e5355290a8b6eba225215f2f 314 Pfam PF00551 Formyl transferase 1 179 2.9E-44 T 11-10-2018 IPR002376 Formyl transferase, N-terminal GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFK25_05425 2db02869e5355290a8b6eba225215f2f 314 Gene3D G3DSA:3.40.50.170 1 205 1.2E-89 T 11-10-2018 AFK25_05425 2db02869e5355290a8b6eba225215f2f 314 Gene3D G3DSA:3.10.25.10 206 312 8.8E-41 T 11-10-2018 IPR037022 Formyl transferase, C-terminal domain superfamily GO:0009058|GO:0016742 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9 AFK25_05425 2db02869e5355290a8b6eba225215f2f 314 Hamap MF_00182 Methionyl-tRNA formyltransferase [fmt]. 1 304 36.894 T 11-10-2018 IPR005794 Methionyl-tRNA formyltransferase GO:0004479|GO:0071951 KEGG: 00670+2.1.2.9|KEGG: 00970+2.1.2.9|Reactome: R-HSA-5368286 AFK25_05425 2db02869e5355290a8b6eba225215f2f 314 SUPERFAMILY SSF50486 204 309 2.2E-33 T 11-10-2018 IPR011034 Formyl transferase-like, C-terminal domain superfamily GO:0003824 AFK25_13805 48b5197bec9c989ad2136ff8e8e6a6c8 333 Pfam PF00146 NADH dehydrogenase 25 326 1.3E-125 T 11-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13805 48b5197bec9c989ad2136ff8e8e6a6c8 333 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 14 332 25.175 T 11-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13805 48b5197bec9c989ad2136ff8e8e6a6c8 333 ProSitePatterns PS00668 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. 216 229 - T 11-10-2018 IPR018086 NADH:ubiquinone oxidoreductase, subunit 1, conserved site GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_11595 6b6260be416ba28a8ed3f402f97501d1 238 SMART SM00448 3 114 1.3E-46 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_11595 6b6260be416ba28a8ed3f402f97501d1 238 SUPERFAMILY SSF52172 4 120 2.56E-42 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_11595 6b6260be416ba28a8ed3f402f97501d1 238 SMART SM00862 155 231 2.3E-30 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFK25_11595 6b6260be416ba28a8ed3f402f97501d1 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 231 7.0E-31 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFK25_11595 6b6260be416ba28a8ed3f402f97501d1 238 SUPERFAMILY SSF46894 131 232 6.52E-32 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFK25_11595 6b6260be416ba28a8ed3f402f97501d1 238 Gene3D G3DSA:3.40.50.2300 1 133 4.6E-38 T 11-10-2018 AFK25_11595 6b6260be416ba28a8ed3f402f97501d1 238 Gene3D G3DSA:1.10.10.10 134 237 4.1E-37 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_11595 6b6260be416ba28a8ed3f402f97501d1 238 Pfam PF00072 Response regulator receiver domain 6 114 2.9E-29 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_09705 7342ba65f28389ff0baf6c9609f55020 374 PIRSF PIRSF001123 295 374 3.8E-4 T 11-10-2018 IPR008007 Peptidase M42 AFK25_09705 7342ba65f28389ff0baf6c9609f55020 374 PIRSF PIRSF001123 4 84 0.12 T 11-10-2018 IPR008007 Peptidase M42 AFK25_09705 7342ba65f28389ff0baf6c9609f55020 374 PIRSF PIRSF001123 81 184 5.1E-5 T 11-10-2018 IPR008007 Peptidase M42 AFK25_09705 7342ba65f28389ff0baf6c9609f55020 374 SUPERFAMILY SSF55031 180 285 5.5E-22 T 11-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain AFK25_09705 7342ba65f28389ff0baf6c9609f55020 374 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 72 81 - T 11-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 AFK25_09705 7342ba65f28389ff0baf6c9609f55020 374 Gene3D G3DSA:3.40.630.10 14 363 2.1E-138 T 11-10-2018 AFK25_09705 7342ba65f28389ff0baf6c9609f55020 374 Pfam PF01546 Peptidase family M20/M25/M40 74 368 7.3E-24 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 AFK25_09705 7342ba65f28389ff0baf6c9609f55020 374 Gene3D G3DSA:3.30.70.360 177 288 2.1E-138 T 11-10-2018 AFK25_09705 7342ba65f28389ff0baf6c9609f55020 374 SUPERFAMILY SSF53187 5 371 2.04E-65 T 11-10-2018 AFK25_09705 7342ba65f28389ff0baf6c9609f55020 374 ProSitePatterns PS00759 ArgE / dapE / ACY1 / CPG2 / yscS family signature 2. 105 143 - T 11-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 AFK25_09705 7342ba65f28389ff0baf6c9609f55020 374 Pfam PF07687 Peptidase dimerisation domain 181 274 8.3E-17 T 11-10-2018 IPR011650 Peptidase M20, dimerisation domain AFK25_09705 7342ba65f28389ff0baf6c9609f55020 374 TIGRFAM TIGR01883 PepT-like: peptidase T-like protein 6 368 4.4E-162 T 11-10-2018 IPR010162 Peptidase M20B, peptidase T-like AFK25_07005 c8bb6a10d3621b9dc7d15cacc92423f3 250 SUPERFAMILY SSF100950 74 228 6.38E-35 T 11-10-2018 IPR037171 NagB/RpiA transferase-like AFK25_07005 c8bb6a10d3621b9dc7d15cacc92423f3 250 SUPERFAMILY SSF46785 5 66 4.15E-13 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_07005 c8bb6a10d3621b9dc7d15cacc92423f3 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 24 38 1.4E-7 T 11-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFK25_07005 c8bb6a10d3621b9dc7d15cacc92423f3 250 PRINTS PR00037 LacR bacterial regulatory protein HTH signature 38 56 1.4E-7 T 11-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFK25_07005 c8bb6a10d3621b9dc7d15cacc92423f3 250 Gene3D G3DSA:1.10.10.10 2 55 2.7E-5 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_07005 c8bb6a10d3621b9dc7d15cacc92423f3 250 Pfam PF08220 DeoR-like helix-turn-helix domain 6 61 4.0E-15 T 11-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFK25_07005 c8bb6a10d3621b9dc7d15cacc92423f3 250 Pfam PF00455 DeoR C terminal sensor domain 75 229 3.7E-49 T 11-10-2018 IPR014036 DeoR C-terminal sensor domain AFK25_07005 c8bb6a10d3621b9dc7d15cacc92423f3 250 SMART SM00420 6 58 1.1E-15 T 11-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFK25_07005 c8bb6a10d3621b9dc7d15cacc92423f3 250 ProSitePatterns PS00894 DeoR-type HTH domain signature. 6 40 - T 11-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 AFK25_07005 c8bb6a10d3621b9dc7d15cacc92423f3 250 SMART SM01134 73 231 3.2E-69 T 11-10-2018 AFK25_00540 3086976428e97c470e0d2698c7c836ff 141 Gene3D G3DSA:3.30.1550.10 2 71 4.0E-35 T 11-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily AFK25_00540 3086976428e97c470e0d2698c7c836ff 141 Gene3D G3DSA:1.10.10.250 72 140 6.2E-30 T 11-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily AFK25_00540 3086976428e97c470e0d2698c7c836ff 141 SUPERFAMILY SSF46906 67 140 9.03E-28 T 11-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily AFK25_00540 3086976428e97c470e0d2698c7c836ff 141 Pfam PF00298 Ribosomal protein L11, RNA binding domain 71 139 1.9E-26 T 11-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 AFK25_00540 3086976428e97c470e0d2698c7c836ff 141 ProSitePatterns PS00359 Ribosomal protein L11 signature. 126 141 - T 11-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00540 3086976428e97c470e0d2698c7c836ff 141 TIGRFAM TIGR01632 L11_bact: ribosomal protein uL11 3 141 1.7E-66 T 11-10-2018 IPR006519 Ribosomal protein L11, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00540 3086976428e97c470e0d2698c7c836ff 141 SMART SM00649 9 140 7.8E-90 T 11-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 AFK25_00540 3086976428e97c470e0d2698c7c836ff 141 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 5 141 32.101 T 11-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 AFK25_00540 3086976428e97c470e0d2698c7c836ff 141 SUPERFAMILY SSF54747 2 84 3.14E-31 T 11-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily AFK25_00540 3086976428e97c470e0d2698c7c836ff 141 Pfam PF03946 Ribosomal protein L11, N-terminal domain 9 66 3.0E-32 T 11-10-2018 IPR020784 Ribosomal protein L11, N-terminal AFK25_00540 3086976428e97c470e0d2698c7c836ff 141 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 36 73 3.0E-16 T 11-10-2018 AFK25_05860 10a3bf55957f378c8918b0fc20791636 564 Hamap MF_01569 Proline--tRNA ligase [proS]. 1 564 41.64 T 11-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 AFK25_05860 10a3bf55957f378c8918b0fc20791636 564 PRINTS PR01046 Prolyl-tRNA synthetase signature 104 115 1.6E-17 T 11-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFK25_05860 10a3bf55957f378c8918b0fc20791636 564 PRINTS PR01046 Prolyl-tRNA synthetase signature 134 142 1.6E-17 T 11-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFK25_05860 10a3bf55957f378c8918b0fc20791636 564 PRINTS PR01046 Prolyl-tRNA synthetase signature 144 155 1.6E-17 T 11-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFK25_05860 10a3bf55957f378c8918b0fc20791636 564 PRINTS PR01046 Prolyl-tRNA synthetase signature 68 86 1.6E-17 T 11-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AFK25_05860 10a3bf55957f378c8918b0fc20791636 564 SUPERFAMILY SSF55681 9 473 2.58E-106 T 11-10-2018 AFK25_05860 10a3bf55957f378c8918b0fc20791636 564 Gene3D G3DSA:3.40.50.800 4 549 3.8E-257 T 11-10-2018 IPR036621 Anticodon-binding domain superfamily AFK25_05860 10a3bf55957f378c8918b0fc20791636 564 Gene3D G3DSA:3.30.930.10 11 461 3.8E-257 T 11-10-2018 AFK25_05860 10a3bf55957f378c8918b0fc20791636 564 PIRSF PIRSF001535 1 564 2.1E-272 T 11-10-2018 IPR023717 Prolyl-tRNA synthetase, class IIa, type 1 GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 AFK25_05860 10a3bf55957f378c8918b0fc20791636 564 Pfam PF04073 Aminoacyl-tRNA editing domain 257 373 5.1E-28 T 11-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AFK25_05860 10a3bf55957f378c8918b0fc20791636 564 SUPERFAMILY SSF55826 218 385 1.31E-32 T 11-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 AFK25_05860 10a3bf55957f378c8918b0fc20791636 564 Pfam PF03129 Anticodon binding domain 474 561 1.8E-20 T 11-10-2018 IPR004154 Anticodon-binding AFK25_05860 10a3bf55957f378c8918b0fc20791636 564 TIGRFAM TIGR00409 proS_fam_II: proline--tRNA ligase 1 561 8.6E-249 T 11-10-2018 IPR004500 Prolyl-tRNA synthetase, class IIa, bacterial-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15 AFK25_05860 10a3bf55957f378c8918b0fc20791636 564 SUPERFAMILY SSF52954 459 564 2.45E-28 T 11-10-2018 AFK25_05860 10a3bf55957f378c8918b0fc20791636 564 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 95 455 8.5E-59 T 11-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_05860 10a3bf55957f378c8918b0fc20791636 564 Gene3D G3DSA:3.90.960.10 240 385 3.8E-257 T 11-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 AFK25_13950 6a0c0f17542b3da6a72e4aff3d1bc877 428 SMART SM00357 57 122 1.1E-19 T 11-10-2018 IPR011129 Cold shock domain GO:0003676 AFK25_13950 6a0c0f17542b3da6a72e4aff3d1bc877 428 TIGRFAM TIGR00767 rho: transcription termination factor Rho 8 416 1.3E-206 T 11-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 AFK25_13950 6a0c0f17542b3da6a72e4aff3d1bc877 428 SUPERFAMILY SSF52540 94 372 7.08E-67 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_13950 6a0c0f17542b3da6a72e4aff3d1bc877 428 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 160 364 1.4E-18 T 11-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFK25_13950 6a0c0f17542b3da6a72e4aff3d1bc877 428 Gene3D G3DSA:3.40.50.300 134 416 8.1E-125 T 11-10-2018 AFK25_13950 6a0c0f17542b3da6a72e4aff3d1bc877 428 Pfam PF07498 Rho termination factor, N-terminal domain 11 52 1.1E-16 T 11-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 AFK25_13950 6a0c0f17542b3da6a72e4aff3d1bc877 428 Pfam PF07497 Rho termination factor, RNA-binding domain 56 129 1.4E-31 T 11-10-2018 IPR011113 Rho termination factor, RNA-binding domain GO:0003723|GO:0006353 AFK25_13950 6a0c0f17542b3da6a72e4aff3d1bc877 428 SUPERFAMILY SSF68912 7 52 3.73E-11 T 11-10-2018 IPR036269 Rho termination factor, N-terminal domain superfamily AFK25_13950 6a0c0f17542b3da6a72e4aff3d1bc877 428 Hamap MF_01884 Transcription termination factor Rho [rho]. 1 418 224.024 T 11-10-2018 IPR004665 Transcription termination factor Rho GO:0003723|GO:0005524|GO:0006353|GO:0008186 AFK25_13950 6a0c0f17542b3da6a72e4aff3d1bc877 428 SMART SM00959 10 52 7.9E-18 T 11-10-2018 IPR011112 Rho termination factor, N-terminal GO:0006353 AFK25_13950 6a0c0f17542b3da6a72e4aff3d1bc877 428 SMART SM00382 171 356 4.1E-8 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_13950 6a0c0f17542b3da6a72e4aff3d1bc877 428 Gene3D G3DSA:2.40.50.140 51 127 1.5E-29 T 11-10-2018 AFK25_13950 6a0c0f17542b3da6a72e4aff3d1bc877 428 Gene3D G3DSA:1.10.720.10 2 50 2.5E-21 T 11-10-2018 AFK25_13950 6a0c0f17542b3da6a72e4aff3d1bc877 428 SUPERFAMILY SSF50249 53 117 3.03E-7 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_05395 4c943abb1be0711b91afd0073aa16834 292 Pfam PF08340 Domain of unknown function (DUF1732) 208 292 2.2E-35 T 11-10-2018 IPR013551 Domain of unknown function DUF1732 AFK25_05395 4c943abb1be0711b91afd0073aa16834 292 TIGRFAM TIGR00255 TIGR00255: TIGR00255 family protein 1 292 9.8E-92 T 11-10-2018 IPR005229 Conserved hypothetical protein CHP00255 AFK25_05395 4c943abb1be0711b91afd0073aa16834 292 Pfam PF03755 YicC-like family, N-terminal region 2 156 5.0E-42 T 11-10-2018 IPR013527 YicC-like, N-terminal AFK25_08985 396fa418a38e20db35b68fa9c7b3a2f8 436 Pfam PF01926 50S ribosome-binding GTPase 178 295 7.3E-27 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_08985 396fa418a38e20db35b68fa9c7b3a2f8 436 Pfam PF01926 50S ribosome-binding GTPase 6 120 4.1E-25 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_08985 396fa418a38e20db35b68fa9c7b3a2f8 436 Gene3D G3DSA:3.40.50.300 1 163 5.4E-48 T 11-10-2018 AFK25_08985 396fa418a38e20db35b68fa9c7b3a2f8 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 2 158 8.2E-26 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFK25_08985 396fa418a38e20db35b68fa9c7b3a2f8 436 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 176 339 2.7E-27 T 11-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AFK25_08985 396fa418a38e20db35b68fa9c7b3a2f8 436 SUPERFAMILY SSF52540 138 433 3.26E-74 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_08985 396fa418a38e20db35b68fa9c7b3a2f8 436 PIRSF PIRSF006485 2 436 4.7E-178 T 11-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 AFK25_08985 396fa418a38e20db35b68fa9c7b3a2f8 436 Hamap MF_00195 GTPase Der [der]. 3 436 41.795 T 11-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 AFK25_08985 396fa418a38e20db35b68fa9c7b3a2f8 436 SUPERFAMILY SSF52540 5 166 1.92E-46 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_08985 396fa418a38e20db35b68fa9c7b3a2f8 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 248 266 6.8E-5 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_08985 396fa418a38e20db35b68fa9c7b3a2f8 436 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 178 198 6.8E-5 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_08985 396fa418a38e20db35b68fa9c7b3a2f8 436 Pfam PF14714 KH-domain-like of EngA bacterial GTPase enzymes, C-terminal 353 433 8.5E-36 T 11-10-2018 IPR032859 GTPase Der, C-terminal KH-domain-like AFK25_08985 396fa418a38e20db35b68fa9c7b3a2f8 436 Gene3D G3DSA:3.30.300.20 353 436 7.0E-37 T 11-10-2018 IPR015946 K homology domain-like, alpha/beta AFK25_08985 396fa418a38e20db35b68fa9c7b3a2f8 436 Gene3D G3DSA:3.40.50.300 171 352 5.0E-57 T 11-10-2018 AFK25_08985 396fa418a38e20db35b68fa9c7b3a2f8 436 TIGRFAM TIGR03594 GTPase_EngA: ribosome-associated GTPase EngA 4 432 1.3E-184 T 11-10-2018 IPR016484 GTP-binding protein EngA GO:0005525 AFK25_04830 77314406e12ac34448352488c7e04d4c 153 Pfam PF00578 AhpC/TSA family 19 124 7.7E-10 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFK25_04830 77314406e12ac34448352488c7e04d4c 153 SUPERFAMILY SSF52833 2 139 7.5E-30 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_04830 77314406e12ac34448352488c7e04d4c 153 Gene3D G3DSA:3.40.30.10 1 146 1.2E-31 T 11-10-2018 AFK25_05970 ebde702e15d32a0bbbaea69f62242199 237 Pfam PF00574 Clp protease 37 213 2.6E-36 T 11-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA AFK25_05970 ebde702e15d32a0bbbaea69f62242199 237 SUPERFAMILY SSF52096 25 221 5.13E-41 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFK25_05970 ebde702e15d32a0bbbaea69f62242199 237 Gene3D G3DSA:3.90.226.10 33 215 1.6E-33 T 11-10-2018 AFK25_04240 f5e9d00e2895b444e024a1136c1c1dcf 470 PIRSF PIRSF006060 8 468 2.4E-95 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFK25_04240 f5e9d00e2895b444e024a1136c1c1dcf 470 Gene3D G3DSA:1.20.1740.10 21 468 4.7E-136 T 11-10-2018 AFK25_04240 f5e9d00e2895b444e024a1136c1c1dcf 470 Pfam PF13520 Amino acid permease 26 427 7.5E-59 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFK25_05390 55f356e4bb67f206257310c49307b341 889 Pfam PF00690 Cation transporter/ATPase, N-terminus 3 71 3.9E-19 T 11-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 AFK25_05390 55f356e4bb67f206257310c49307b341 889 Gene3D G3DSA:3.40.1110.10 333 534 0.0 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFK25_05390 55f356e4bb67f206257310c49307b341 889 Gene3D G3DSA:2.70.150.10 16 226 0.0 T 11-10-2018 AFK25_05390 55f356e4bb67f206257310c49307b341 889 TIGRFAM TIGR01522 ATPase-IIA2_Ca: calcium-transporting P-type ATPase, PMR1-type 6 874 4.0E-241 T 11-10-2018 IPR006413 P-type ATPase, subfamily IIA, PMR1-type GO:0005388|GO:0006816|GO:0016021 Reactome: R-HSA-936837 AFK25_05390 55f356e4bb67f206257310c49307b341 889 Gene3D G3DSA:1.20.1110.10 54 874 0.0 T 11-10-2018 AFK25_05390 55f356e4bb67f206257310c49307b341 889 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 661 686 5.5E-17 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFK25_05390 55f356e4bb67f206257310c49307b341 889 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 601 617 5.5E-17 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFK25_05390 55f356e4bb67f206257310c49307b341 889 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 629 645 5.5E-17 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFK25_05390 55f356e4bb67f206257310c49307b341 889 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 485 503 5.5E-17 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFK25_05390 55f356e4bb67f206257310c49307b341 889 Pfam PF00122 E1-E2 ATPase 111 303 2.1E-56 T 11-10-2018 AFK25_05390 55f356e4bb67f206257310c49307b341 889 SUPERFAMILY SSF81665 2 878 1.44E-138 T 11-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AFK25_05390 55f356e4bb67f206257310c49307b341 889 SUPERFAMILY SSF81653 116 223 8.37E-32 T 11-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AFK25_05390 55f356e4bb67f206257310c49307b341 889 Pfam PF00702 haloacid dehalogenase-like hydrolase 321 643 9.8E-27 T 11-10-2018 AFK25_05390 55f356e4bb67f206257310c49307b341 889 Gene3D G3DSA:3.40.50.1000 320 674 0.0 T 11-10-2018 IPR023214 HAD superfamily AFK25_05390 55f356e4bb67f206257310c49307b341 889 SMART SM00831 2 76 6.1E-28 T 11-10-2018 IPR004014 Cation-transporting P-type ATPase, N-terminal Reactome: R-HSA-936837 AFK25_05390 55f356e4bb67f206257310c49307b341 889 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 161 175 7.9E-40 T 11-10-2018 AFK25_05390 55f356e4bb67f206257310c49307b341 889 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 527 538 7.9E-40 T 11-10-2018 AFK25_05390 55f356e4bb67f206257310c49307b341 889 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 629 648 7.9E-40 T 11-10-2018 AFK25_05390 55f356e4bb67f206257310c49307b341 889 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 549 559 7.9E-40 T 11-10-2018 AFK25_05390 55f356e4bb67f206257310c49307b341 889 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 323 337 7.9E-40 T 11-10-2018 AFK25_05390 55f356e4bb67f206257310c49307b341 889 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 653 665 7.9E-40 T 11-10-2018 AFK25_05390 55f356e4bb67f206257310c49307b341 889 SUPERFAMILY SSF56784 321 733 2.24E-64 T 11-10-2018 IPR036412 HAD-like superfamily AFK25_05390 55f356e4bb67f206257310c49307b341 889 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 83 344 5.9E-47 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFK25_05390 55f356e4bb67f206257310c49307b341 889 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 597 719 2.0E-36 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFK25_05390 55f356e4bb67f206257310c49307b341 889 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 426 574 2.9E-19 T 11-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AFK25_05390 55f356e4bb67f206257310c49307b341 889 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 325 331 - T 11-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AFK25_05390 55f356e4bb67f206257310c49307b341 889 SUPERFAMILY SSF81660 331 531 2.62E-59 T 11-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AFK25_05390 55f356e4bb67f206257310c49307b341 889 Pfam PF00689 Cation transporting ATPase, C-terminus 713 878 1.6E-53 T 11-10-2018 IPR006068 Cation-transporting P-type ATPase, C-terminal Reactome: R-HSA-936837 AFK25_05390 55f356e4bb67f206257310c49307b341 889 TIGRFAM TIGR01116 ATPase-IIA1_Ca: calcium-translocating P-type ATPase, SERCA-type 54 879 2.6E-217 T 11-10-2018 IPR005782 P-type ATPase, subfamily IIA, SERCA-type GO:0005388|GO:0006816|GO:0016021 Reactome: R-HSA-1912420|Reactome: R-HSA-418359|Reactome: R-HSA-5578775|Reactome: R-HSA-936837 AFK25_02400 34824b605ceff96229d9fd3c97d8f049 338 Gene3D G3DSA:3.15.30.10 28 327 2.0E-107 T 11-10-2018 AFK25_02400 34824b605ceff96229d9fd3c97d8f049 338 Gene3D G3DSA:3.30.1930.10 156 280 2.0E-107 T 11-10-2018 AFK25_02400 34824b605ceff96229d9fd3c97d8f049 338 Pfam PF03864 Phage major capsid protein E 6 336 8.2E-94 T 11-10-2018 IPR005564 Major capsid protein GpE AFK25_12570 dc93f419961e0ad1d1f9075269040c3b 442 SUPERFAMILY SSF53098 272 437 1.82E-28 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_12570 dc93f419961e0ad1d1f9075269040c3b 442 Pfam PF13276 HTH-like domain 195 250 1.5E-11 T 11-10-2018 IPR025948 HTH-like domain AFK25_12570 dc93f419961e0ad1d1f9075269040c3b 442 Gene3D G3DSA:3.30.420.10 275 439 2.3E-8 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFK25_12570 dc93f419961e0ad1d1f9075269040c3b 442 Pfam PF00665 Integrase core domain 280 395 6.4E-22 T 11-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFK25_06765 dc93f419961e0ad1d1f9075269040c3b 442 SUPERFAMILY SSF53098 272 437 1.82E-28 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_06765 dc93f419961e0ad1d1f9075269040c3b 442 Pfam PF13276 HTH-like domain 195 250 1.5E-11 T 11-10-2018 IPR025948 HTH-like domain AFK25_06765 dc93f419961e0ad1d1f9075269040c3b 442 Gene3D G3DSA:3.30.420.10 275 439 2.3E-8 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFK25_06765 dc93f419961e0ad1d1f9075269040c3b 442 Pfam PF00665 Integrase core domain 280 395 6.4E-22 T 11-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFK25_10865 dc93f419961e0ad1d1f9075269040c3b 442 SUPERFAMILY SSF53098 272 437 1.82E-28 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_10865 dc93f419961e0ad1d1f9075269040c3b 442 Pfam PF13276 HTH-like domain 195 250 1.5E-11 T 11-10-2018 IPR025948 HTH-like domain AFK25_10865 dc93f419961e0ad1d1f9075269040c3b 442 Gene3D G3DSA:3.30.420.10 275 439 2.3E-8 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFK25_10865 dc93f419961e0ad1d1f9075269040c3b 442 Pfam PF00665 Integrase core domain 280 395 6.4E-22 T 11-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFK25_05055 dc93f419961e0ad1d1f9075269040c3b 442 SUPERFAMILY SSF53098 272 437 1.82E-28 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_05055 dc93f419961e0ad1d1f9075269040c3b 442 Pfam PF13276 HTH-like domain 195 250 1.5E-11 T 11-10-2018 IPR025948 HTH-like domain AFK25_05055 dc93f419961e0ad1d1f9075269040c3b 442 Gene3D G3DSA:3.30.420.10 275 439 2.3E-8 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFK25_05055 dc93f419961e0ad1d1f9075269040c3b 442 Pfam PF00665 Integrase core domain 280 395 6.4E-22 T 11-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFK25_07075 665d1f324417b180305a188d24eeef19 144 Gene3D G3DSA:3.40.30.10 25 144 1.9E-54 T 11-10-2018 AFK25_07075 665d1f324417b180305a188d24eeef19 144 TIGRFAM TIGR04191 YphP_YqiW: putative bacilliredoxin, YphP/YqiW family 8 144 1.3E-64 T 11-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family AFK25_07075 665d1f324417b180305a188d24eeef19 144 Pfam PF06491 Disulphide isomerase 8 144 3.5E-62 T 11-10-2018 IPR009474 Putative bacilliredoxin, YphP/YqiW family AFK25_12725 a4301564618b3991c64f2a8df3da6e33 148 TIGRFAM TIGR01994 SUF_scaf_2: SUF system FeS assembly protein, NifU family 7 141 1.3E-59 T 11-10-2018 AFK25_12725 a4301564618b3991c64f2a8df3da6e33 148 Gene3D G3DSA:3.90.1010.10 1 148 2.7E-63 T 11-10-2018 AFK25_12725 a4301564618b3991c64f2a8df3da6e33 148 SUPERFAMILY SSF82649 1 143 2.51E-55 T 11-10-2018 AFK25_12725 a4301564618b3991c64f2a8df3da6e33 148 Pfam PF01592 NifU-like N terminal domain 11 129 1.2E-37 T 11-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 AFK25_08800 67fca9e535c4dacdf67819242923baa2 230 Gene3D G3DSA:3.40.50.10320 1 230 2.8E-89 T 11-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 AFK25_08800 67fca9e535c4dacdf67819242923baa2 230 SUPERFAMILY SSF102588 1 220 5.36E-58 T 11-10-2018 IPR024078 Putative deacetylase LmbE-like domain superfamily Reactome: R-HSA-162710 AFK25_08800 67fca9e535c4dacdf67819242923baa2 230 TIGRFAM TIGR04001 thiol_BshB1: bacillithiol biosynthesis deacetylase BshB1 2 220 8.9E-99 T 11-10-2018 IPR023842 Bacillithiol biosynthesis deacetylase, BshB1 GO:0019213|GO:0071793 AFK25_08800 67fca9e535c4dacdf67819242923baa2 230 Pfam PF02585 GlcNAc-PI de-N-acetylase 4 120 2.0E-22 T 11-10-2018 IPR003737 N-acetylglucosaminyl phosphatidylinositol deacetylase-related Reactome: R-HSA-162710 AFK25_01935 e47ac02605f1d0388849e23e484b01b5 322 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 235 300 1.8E-16 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFK25_01935 e47ac02605f1d0388849e23e484b01b5 322 Pfam PF00005 ABC transporter 33 183 1.8E-35 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_01935 e47ac02605f1d0388849e23e484b01b5 322 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 320 6.7E-28 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFK25_01935 e47ac02605f1d0388849e23e484b01b5 322 SMART SM00382 41 233 2.2E-17 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_01935 e47ac02605f1d0388849e23e484b01b5 322 SUPERFAMILY SSF52540 5 255 1.85E-78 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_01935 e47ac02605f1d0388849e23e484b01b5 322 Gene3D G3DSA:3.40.50.300 3 322 7.2E-107 T 11-10-2018 AFK25_01935 e47ac02605f1d0388849e23e484b01b5 322 ProSitePatterns PS00211 ABC transporters family signature. 156 170 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_02750 2cc1211bdc775d544eca6adfcf7813f2 66 ProSitePatterns PS00684 Small, acid-soluble spore proteins, alpha/beta type, signature 2. 38 52 - T 11-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 AFK25_02750 2cc1211bdc775d544eca6adfcf7813f2 66 Gene3D G3DSA:1.10.8.910 5 66 3.8E-31 T 11-10-2018 IPR038300 SASP, alpha/beta-type superfamily AFK25_02750 2cc1211bdc775d544eca6adfcf7813f2 66 ProSitePatterns PS00304 Small, acid-soluble spore proteins, alpha/beta type, signature 1. 20 29 - T 11-10-2018 IPR018126 Small acid-soluble spore protein, alpha/beta-type, conserved site GO:0003690|GO:0006265 AFK25_02750 2cc1211bdc775d544eca6adfcf7813f2 66 Pfam PF00269 Small, acid-soluble spore proteins, alpha/beta type 5 59 3.2E-22 T 11-10-2018 IPR001448 Small acid-soluble spore protein, alpha/beta-type GO:0003690|GO:0006265 AFK25_00310 f2cde2d100be20b3449aa5f962779310 483 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 386 448 1.9E-8 T 11-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core AFK25_00310 f2cde2d100be20b3449aa5f962779310 483 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 252 325 3.2E-29 T 11-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core AFK25_00310 f2cde2d100be20b3449aa5f962779310 483 TIGRFAM TIGR00444 mazG: MazG family protein 236 479 1.1E-101 T 11-10-2018 IPR011551 NTP pyrophosphohydrolase MazG AFK25_00310 f2cde2d100be20b3449aa5f962779310 483 Gene3D G3DSA:1.10.287.1080 353 482 7.5E-44 T 11-10-2018 AFK25_00310 f2cde2d100be20b3449aa5f962779310 483 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 3 203 1.6E-27 T 11-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFK25_00310 f2cde2d100be20b3449aa5f962779310 483 Gene3D G3DSA:3.40.1010.10 3 114 2.2E-10 T 11-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFK25_00310 f2cde2d100be20b3449aa5f962779310 483 SUPERFAMILY SSF53790 2 260 2.62E-35 T 11-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFK25_00310 f2cde2d100be20b3449aa5f962779310 483 SUPERFAMILY SSF101386 363 459 1.33E-23 T 11-10-2018 AFK25_00310 f2cde2d100be20b3449aa5f962779310 483 Gene3D G3DSA:1.10.287.1080 227 350 1.6E-43 T 11-10-2018 AFK25_00310 f2cde2d100be20b3449aa5f962779310 483 SUPERFAMILY SSF101386 232 328 7.12E-25 T 11-10-2018 AFK25_00310 f2cde2d100be20b3449aa5f962779310 483 PIRSF PIRSF002845 1 482 1.0E-219 T 11-10-2018 IPR024180 Bifunctional tetrapyrrole methylase/MazG NTP pyrophosphohydrolase, predicted AFK25_10970 25d2dc6bede2b3ae0cbef9f7d247a310 224 Gene3D G3DSA:1.10.150.20 46 87 1.8E-8 T 11-10-2018 AFK25_10970 25d2dc6bede2b3ae0cbef9f7d247a310 224 SUPERFAMILY SSF102712 153 190 2.75E-5 T 11-10-2018 AFK25_10970 25d2dc6bede2b3ae0cbef9f7d247a310 224 ProSitePatterns PS01302 Uncharacterized protein family UPF0758 signature. 173 178 - T 11-10-2018 IPR020891 Uncharacterised protein family UPF0758, conserved site AFK25_10970 25d2dc6bede2b3ae0cbef9f7d247a310 224 Gene3D G3DSA:3.40.140.10 100 224 3.0E-48 T 11-10-2018 AFK25_10970 25d2dc6bede2b3ae0cbef9f7d247a310 224 Pfam PF04002 RadC-like JAB domain 103 222 2.4E-48 T 11-10-2018 IPR025657 RadC-like JAB domain AFK25_10970 25d2dc6bede2b3ae0cbef9f7d247a310 224 SUPERFAMILY SSF47781 15 91 9.27E-11 T 11-10-2018 IPR010994 RuvA domain 2-like AFK25_10970 25d2dc6bede2b3ae0cbef9f7d247a310 224 TIGRFAM TIGR00608 radc: DNA repair protein RadC 11 223 6.5E-86 T 11-10-2018 IPR001405 Uncharacterised protein family UPF0758 AFK25_10970 25d2dc6bede2b3ae0cbef9f7d247a310 224 Pfam PF12826 Helix-hairpin-helix motif 45 86 5.1E-7 T 11-10-2018 AFK25_05380 bb42a1c6b7a3f738907de715a73a27e1 145 Gene3D G3DSA:1.20.5.170 1 49 7.8E-12 T 11-10-2018 AFK25_06185 92d8b675dcceb7a8d336ee02b6524bbb 379 Pfam PF13646 HEAT repeats 267 343 1.2E-11 T 11-10-2018 AFK25_06185 92d8b675dcceb7a8d336ee02b6524bbb 379 SUPERFAMILY SSF110836 1 87 3.14E-23 T 11-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily AFK25_06185 92d8b675dcceb7a8d336ee02b6524bbb 379 SUPERFAMILY SSF48371 192 373 6.17E-37 T 11-10-2018 IPR016024 Armadillo-type fold AFK25_06185 92d8b675dcceb7a8d336ee02b6524bbb 379 Gene3D G3DSA:3.30.1370.70 1 91 1.5E-28 T 11-10-2018 IPR036498 Scaffold protein Nfu/NifU, N-terminal domain superfamily AFK25_06185 92d8b675dcceb7a8d336ee02b6524bbb 379 Pfam PF08712 Scaffold protein Nfu/NifU N terminal 6 87 1.4E-19 T 11-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal AFK25_06185 92d8b675dcceb7a8d336ee02b6524bbb 379 Pfam PF13769 Virulence factor 109 189 5.4E-26 T 11-10-2018 IPR025989 Virulence factor domain AFK25_06185 92d8b675dcceb7a8d336ee02b6524bbb 379 Gene3D G3DSA:1.25.10.10 190 377 8.6E-29 T 11-10-2018 IPR011989 Armadillo-like helical AFK25_06185 92d8b675dcceb7a8d336ee02b6524bbb 379 SMART SM00567 E-Z type HEAT repeats 279 308 0.038 T 11-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 AFK25_06185 92d8b675dcceb7a8d336ee02b6524bbb 379 SMART SM00567 E-Z type HEAT repeats 218 246 36.0 T 11-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 AFK25_06185 92d8b675dcceb7a8d336ee02b6524bbb 379 SMART SM00567 E-Z type HEAT repeats 248 277 3.6 T 11-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 AFK25_06185 92d8b675dcceb7a8d336ee02b6524bbb 379 SMART SM00567 E-Z type HEAT repeats 310 339 0.0015 T 11-10-2018 IPR004155 PBS lyase HEAT-like repeat Reactome: R-HSA-204626 AFK25_06185 92d8b675dcceb7a8d336ee02b6524bbb 379 SMART SM00932 4 90 6.3E-24 T 11-10-2018 IPR014824 Scaffold protein Nfu/NifU, N-terminal AFK25_07475 67b242270f8c2d6cb8ad63ce3d199aa3 210 Gene3D G3DSA:3.90.79.10 2 202 1.9E-47 T 11-10-2018 AFK25_07475 67b242270f8c2d6cb8ad63ce3d199aa3 210 SUPERFAMILY SSF55811 7 197 3.93E-28 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFK25_07475 67b242270f8c2d6cb8ad63ce3d199aa3 210 Pfam PF00293 NUDIX domain 29 136 2.7E-11 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFK25_07730 efd080ab3716fbb0fbbb0c98e37369fa 575 Gene3D G3DSA:3.30.450.20 21 151 1.1E-36 T 11-10-2018 AFK25_07730 efd080ab3716fbb0fbbb0c98e37369fa 575 SUPERFAMILY SSF141868 322 570 1.57E-87 T 11-10-2018 IPR035919 EAL domain superfamily AFK25_07730 efd080ab3716fbb0fbbb0c98e37369fa 575 SMART SM00267 136 308 1.3E-69 T 11-10-2018 IPR000160 GGDEF domain AFK25_07730 efd080ab3716fbb0fbbb0c98e37369fa 575 SMART SM00052 317 562 3.2E-107 T 11-10-2018 IPR001633 EAL domain AFK25_07730 efd080ab3716fbb0fbbb0c98e37369fa 575 Pfam PF00990 Diguanylate cyclase, GGDEF domain 148 304 7.2E-53 T 11-10-2018 IPR000160 GGDEF domain AFK25_07730 efd080ab3716fbb0fbbb0c98e37369fa 575 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 26 143 1.7E-23 T 11-10-2018 IPR000014 PAS domain AFK25_07730 efd080ab3716fbb0fbbb0c98e37369fa 575 SMART SM00086 94 136 5.5E-5 T 11-10-2018 IPR001610 PAC motif AFK25_07730 efd080ab3716fbb0fbbb0c98e37369fa 575 Gene3D G3DSA:3.20.20.450 319 569 1.5E-95 T 11-10-2018 IPR035919 EAL domain superfamily AFK25_07730 efd080ab3716fbb0fbbb0c98e37369fa 575 SMART SM00091 22 92 2.3E-8 T 11-10-2018 IPR000014 PAS domain AFK25_07730 efd080ab3716fbb0fbbb0c98e37369fa 575 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 144 307 3.2E-46 T 11-10-2018 IPR000160 GGDEF domain AFK25_07730 efd080ab3716fbb0fbbb0c98e37369fa 575 Gene3D G3DSA:3.30.70.270 152 318 9.7E-61 T 11-10-2018 AFK25_07730 efd080ab3716fbb0fbbb0c98e37369fa 575 SUPERFAMILY SSF55073 152 309 3.61E-54 T 11-10-2018 IPR029787 Nucleotide cyclase AFK25_07730 efd080ab3716fbb0fbbb0c98e37369fa 575 SUPERFAMILY SSF55785 31 133 1.92E-29 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_07730 efd080ab3716fbb0fbbb0c98e37369fa 575 Pfam PF00563 EAL domain 324 557 1.4E-71 T 11-10-2018 IPR001633 EAL domain AFK25_07730 efd080ab3716fbb0fbbb0c98e37369fa 575 Pfam PF00989 PAS fold 26 133 1.2E-16 T 11-10-2018 IPR013767 PAS fold GO:0006355 AFK25_01000 427ca25fbc6f84383ad0ca1f7d6898ae 211 SUPERFAMILY SSF48498 77 190 2.62E-23 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFK25_01000 427ca25fbc6f84383ad0ca1f7d6898ae 211 Gene3D G3DSA:1.10.10.60 6 50 7.2E-19 T 11-10-2018 AFK25_01000 427ca25fbc6f84383ad0ca1f7d6898ae 211 Pfam PF00440 Bacterial regulatory proteins, tetR family 10 53 2.5E-16 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_01000 427ca25fbc6f84383ad0ca1f7d6898ae 211 Gene3D G3DSA:1.10.357.10 51 191 3.1E-34 T 11-10-2018 AFK25_01000 427ca25fbc6f84383ad0ca1f7d6898ae 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 31 54 3.2E-8 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_01000 427ca25fbc6f84383ad0ca1f7d6898ae 211 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 10 23 3.2E-8 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_01000 427ca25fbc6f84383ad0ca1f7d6898ae 211 Pfam PF08359 YsiA-like protein, C-terminal region 64 187 3.1E-4 T 11-10-2018 IPR013570 Transcription regulator YsiA, C-terminal AFK25_01000 427ca25fbc6f84383ad0ca1f7d6898ae 211 SUPERFAMILY SSF46689 4 81 2.15E-17 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_02740 d49ab9a112c8bf0a006443fb0c40daf4 233 SUPERFAMILY SSF161098 29 213 1.96E-47 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_02740 d49ab9a112c8bf0a006443fb0c40daf4 233 Gene3D G3DSA:1.10.3720.10 20 231 1.3E-55 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_02740 d49ab9a112c8bf0a006443fb0c40daf4 233 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 26 122 6.9E-30 T 11-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 AFK25_02740 d49ab9a112c8bf0a006443fb0c40daf4 233 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 46 228 6.0E-26 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_09900 c4c38d3c3c8b930a7a64ff7ef1d6216f 307 Gene3D G3DSA:3.40.50.300 125 283 4.1E-22 T 11-10-2018 AFK25_09900 c4c38d3c3c8b930a7a64ff7ef1d6216f 307 TIGRFAM TIGR02858 spore_III_AA: stage III sporulation protein AA 28 294 4.2E-117 T 11-10-2018 IPR014217 Sporulation stage III, protein AA AFK25_09900 c4c38d3c3c8b930a7a64ff7ef1d6216f 307 SMART SM00382 135 279 2.4E-7 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_09900 c4c38d3c3c8b930a7a64ff7ef1d6216f 307 SUPERFAMILY SSF52540 42 269 6.0E-18 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_07880 f88f3d3e3a3bd60cab1a7116497cf8f2 330 SUPERFAMILY SSF53323 12 222 1.96E-39 T 11-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AFK25_07880 f88f3d3e3a3bd60cab1a7116497cf8f2 330 Gene3D G3DSA:3.30.70.3270 243 327 1.1E-10 T 11-10-2018 AFK25_07880 f88f3d3e3a3bd60cab1a7116497cf8f2 330 Gene3D G3DSA:3.40.920.10 11 198 2.0E-53 T 11-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AFK25_07880 f88f3d3e3a3bd60cab1a7116497cf8f2 330 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 295 306 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFK25_07880 f88f3d3e3a3bd60cab1a7116497cf8f2 330 SUPERFAMILY SSF54862 248 315 7.53E-15 T 11-10-2018 AFK25_07880 f88f3d3e3a3bd60cab1a7116497cf8f2 330 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 13 196 4.0E-35 T 11-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 AFK25_07880 f88f3d3e3a3bd60cab1a7116497cf8f2 330 Pfam PF12838 4Fe-4S dicluster domain 256 309 3.7E-8 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFK25_07880 f88f3d3e3a3bd60cab1a7116497cf8f2 330 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 21 193 5.7E-31 T 11-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AFK25_05930 cb4c9c8fb969ec275c3ef7f1132addc2 413 Gene3D G3DSA:3.30.830.10 218 413 5.2E-62 T 11-10-2018 AFK25_05930 cb4c9c8fb969ec275c3ef7f1132addc2 413 SUPERFAMILY SSF63411 226 411 7.97E-49 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFK25_05930 cb4c9c8fb969ec275c3ef7f1132addc2 413 ProSitePatterns PS00143 Insulinase family, zinc-binding region signature. 33 56 - T 11-10-2018 IPR001431 Peptidase M16, zinc-binding site GO:0004222|GO:0006508 AFK25_05930 cb4c9c8fb969ec275c3ef7f1132addc2 413 SUPERFAMILY SSF63411 3 204 1.31E-60 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFK25_05930 cb4c9c8fb969ec275c3ef7f1132addc2 413 Pfam PF00675 Insulinase (Peptidase family M16) 12 159 7.6E-48 T 11-10-2018 IPR011765 Peptidase M16, N-terminal AFK25_05930 cb4c9c8fb969ec275c3ef7f1132addc2 413 Gene3D G3DSA:3.30.830.10 1 213 6.3E-81 T 11-10-2018 AFK25_05930 cb4c9c8fb969ec275c3ef7f1132addc2 413 Pfam PF05193 Peptidase M16 inactive domain 166 338 2.8E-40 T 11-10-2018 IPR007863 Peptidase M16, C-terminal AFK25_12790 187a5575155e329a23fafe4d86b9918e 127 Hamap MF_00272 Glycine cleavage system H protein [gcvH]. 4 125 40.542 T 11-10-2018 IPR002930 Glycine cleavage system H-protein GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 AFK25_12790 187a5575155e329a23fafe4d86b9918e 127 SUPERFAMILY SSF51230 3 125 7.73E-48 T 11-10-2018 IPR011053 Single hybrid motif AFK25_12790 187a5575155e329a23fafe4d86b9918e 127 TIGRFAM TIGR00527 gcvH: glycine cleavage system H protein 3 127 3.2E-57 T 11-10-2018 IPR017453 Glycine cleavage system H-protein, subgroup GO:0005960|GO:0019464 Reactome: R-HSA-389661|Reactome: R-HSA-6783984 AFK25_12790 187a5575155e329a23fafe4d86b9918e 127 Pfam PF01597 Glycine cleavage H-protein 7 126 8.9E-50 T 11-10-2018 IPR033753 Glycine cleavage system H-protein/Simiate AFK25_12790 187a5575155e329a23fafe4d86b9918e 127 Gene3D G3DSA:2.40.50.100 1 127 8.4E-54 T 11-10-2018 AFK25_12790 187a5575155e329a23fafe4d86b9918e 127 ProSitePatterns PS00189 2-oxo acid dehydrogenases acyltransferase component lipoyl binding site. 47 76 - T 11-10-2018 IPR003016 2-oxo acid dehydrogenase, lipoyl-binding site Reactome: R-HSA-389661 AFK25_04940 878ee4fb1a6e3b81fa5c601a9de95338 260 Gene3D G3DSA:3.30.540.10 1 141 9.2E-46 T 11-10-2018 AFK25_04940 878ee4fb1a6e3b81fa5c601a9de95338 260 ProSitePatterns PS00629 Inositol monophosphatase family signature 1. 82 95 - T 11-10-2018 IPR020583 Inositol monophosphatase, metal-binding site AFK25_04940 878ee4fb1a6e3b81fa5c601a9de95338 260 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 211 225 - T 11-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 AFK25_04940 878ee4fb1a6e3b81fa5c601a9de95338 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 208 232 1.7E-40 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFK25_04940 878ee4fb1a6e3b81fa5c601a9de95338 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 60 76 1.7E-40 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFK25_04940 878ee4fb1a6e3b81fa5c601a9de95338 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 82 98 1.7E-40 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFK25_04940 878ee4fb1a6e3b81fa5c601a9de95338 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 131 154 1.7E-40 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFK25_04940 878ee4fb1a6e3b81fa5c601a9de95338 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 177 198 1.7E-40 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFK25_04940 878ee4fb1a6e3b81fa5c601a9de95338 260 PRINTS PR00377 Inositol monophosphatase superfamily signature 38 58 1.7E-40 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFK25_04940 878ee4fb1a6e3b81fa5c601a9de95338 260 SUPERFAMILY SSF56655 2 259 3.66E-79 T 11-10-2018 AFK25_04940 878ee4fb1a6e3b81fa5c601a9de95338 260 Pfam PF00459 Inositol monophosphatase family 4 258 1.4E-65 T 11-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AFK25_04940 878ee4fb1a6e3b81fa5c601a9de95338 260 Gene3D G3DSA:3.40.190.80 142 260 5.7E-35 T 11-10-2018 AFK25_09855 4e2f0a60b1669ef25d0ce8644611cad7 450 SUPERFAMILY SSF52440 1 113 1.8E-50 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFK25_09855 4e2f0a60b1669ef25d0ce8644611cad7 450 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 323 2.0E-84 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_09855 4e2f0a60b1669ef25d0ce8644611cad7 450 Pfam PF02785 Biotin carboxylase C-terminal domain 337 443 7.0E-46 T 11-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFK25_09855 4e2f0a60b1669ef25d0ce8644611cad7 450 SMART SM00878 337 443 9.7E-74 T 11-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFK25_09855 4e2f0a60b1669ef25d0ce8644611cad7 450 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 287 294 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_09855 4e2f0a60b1669ef25d0ce8644611cad7 450 Gene3D G3DSA:3.30.470.130 1 449 9.9E-205 T 11-10-2018 AFK25_09855 4e2f0a60b1669ef25d0ce8644611cad7 450 SUPERFAMILY SSF56059 83 349 1.68E-72 T 11-10-2018 AFK25_09855 4e2f0a60b1669ef25d0ce8644611cad7 450 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 449 9.8E-245 T 11-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 AFK25_09855 4e2f0a60b1669ef25d0ce8644611cad7 450 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 153 167 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_09855 4e2f0a60b1669ef25d0ce8644611cad7 450 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 2.2E-47 T 11-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFK25_09855 4e2f0a60b1669ef25d0ce8644611cad7 450 SUPERFAMILY SSF51246 332 445 2.41E-48 T 11-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AFK25_13200 960e4d31933f43c0c741318c6e0c32ab 394 PIRSF PIRSF000390 12 392 3.0E-128 T 11-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase AFK25_13200 960e4d31933f43c0c741318c6e0c32ab 394 Gene3D G3DSA:3.90.1150.10 264 394 1.1E-41 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_13200 960e4d31933f43c0c741318c6e0c32ab 394 Pfam PF01041 DegT/DnrJ/EryC1/StrS aminotransferase family 22 385 2.1E-135 T 11-10-2018 IPR000653 DegT/DnrJ/EryC1/StrS aminotransferase AFK25_13200 960e4d31933f43c0c741318c6e0c32ab 394 SUPERFAMILY SSF53383 15 388 1.55E-131 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_13200 960e4d31933f43c0c741318c6e0c32ab 394 Gene3D G3DSA:3.40.640.10 3 263 5.0E-109 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_13200 960e4d31933f43c0c741318c6e0c32ab 394 TIGRFAM TIGR03588 PseC: UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase 15 388 4.4E-160 T 11-10-2018 IPR020026 UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine transaminase AFK25_11880 ed449db1c2bc9ec51cfcb8b31a642ede 360 SMART SM00830 10 89 3.0E-22 T 11-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFK25_11880 ed449db1c2bc9ec51cfcb8b31a642ede 360 Pfam PF01817 Chorismate mutase type II 10 87 1.6E-18 T 11-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFK25_11880 ed449db1c2bc9ec51cfcb8b31a642ede 360 Gene3D G3DSA:3.20.20.70 93 358 1.1E-102 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_11880 ed449db1c2bc9ec51cfcb8b31a642ede 360 SUPERFAMILY SSF51569 31 354 3.11E-103 T 11-10-2018 AFK25_11880 ed449db1c2bc9ec51cfcb8b31a642ede 360 TIGRFAM TIGR01361 DAHP_synth_Bsub: 3-deoxy-7-phosphoheptulonate synthase 95 352 3.1E-124 T 11-10-2018 IPR006268 Phospho-2-dehydro-3-deoxyheptonate aldolase, subtype 2 GO:0009073|GO:0016832 KEGG: 00400+2.5.1.54|MetaCyc: PWY-6164 AFK25_11880 ed449db1c2bc9ec51cfcb8b31a642ede 360 TIGRFAM TIGR01801 CM_A: chorismate mutase 1 102 4.4E-45 T 11-10-2018 IPR010954 Chorismate mutase, Firmicutes/Deinococcus KEGG: 00400+2.5.1.54+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6164|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFK25_11880 ed449db1c2bc9ec51cfcb8b31a642ede 360 Gene3D G3DSA:1.20.59.10 8 92 2.7E-29 T 11-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFK25_11880 ed449db1c2bc9ec51cfcb8b31a642ede 360 Pfam PF00793 DAHP synthetase I family 110 355 1.9E-85 T 11-10-2018 IPR006218 DAHP synthetase I/KDSA GO:0009058 KEGG: 00540+2.5.1.55|MetaCyc: PWY-1269|MetaCyc: PWY-7674 AFK25_08355 908fdfff6b4a177c46a13def3b36ba7a 307 Gene3D G3DSA:1.20.1530.20 151 304 4.0E-7 T 11-10-2018 IPR038770 Sodium/solute symporter superfamily AFK25_08355 908fdfff6b4a177c46a13def3b36ba7a 307 Pfam PF03547 Membrane transport protein 9 155 2.1E-7 T 11-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 AFK25_08355 908fdfff6b4a177c46a13def3b36ba7a 307 Pfam PF03547 Membrane transport protein 158 296 8.0E-16 T 11-10-2018 IPR004776 Membrane transport protein GO:0016021|GO:0055085 AFK25_11730 eb5193a199145041e52ff76ee46dfdb4 397 TIGRFAM TIGR00016 ackA: acetate kinase 2 394 5.1E-177 T 11-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFK25_11730 eb5193a199145041e52ff76ee46dfdb4 397 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 4 15 - T 11-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFK25_11730 eb5193a199145041e52ff76ee46dfdb4 397 Gene3D G3DSA:3.30.420.40 2 194 7.4E-76 T 11-10-2018 AFK25_11730 eb5193a199145041e52ff76ee46dfdb4 397 Gene3D G3DSA:3.30.420.40 195 397 1.8E-84 T 11-10-2018 AFK25_11730 eb5193a199145041e52ff76ee46dfdb4 397 SUPERFAMILY SSF53067 157 394 3.29E-95 T 11-10-2018 AFK25_11730 eb5193a199145041e52ff76ee46dfdb4 397 PRINTS PR00471 Acetate kinase family signature 172 185 8.1E-48 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFK25_11730 eb5193a199145041e52ff76ee46dfdb4 397 PRINTS PR00471 Acetate kinase family signature 202 223 8.1E-48 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFK25_11730 eb5193a199145041e52ff76ee46dfdb4 397 PRINTS PR00471 Acetate kinase family signature 299 312 8.1E-48 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFK25_11730 eb5193a199145041e52ff76ee46dfdb4 397 PRINTS PR00471 Acetate kinase family signature 321 337 8.1E-48 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFK25_11730 eb5193a199145041e52ff76ee46dfdb4 397 PRINTS PR00471 Acetate kinase family signature 375 387 8.1E-48 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFK25_11730 eb5193a199145041e52ff76ee46dfdb4 397 PRINTS PR00471 Acetate kinase family signature 4 15 8.1E-48 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFK25_11730 eb5193a199145041e52ff76ee46dfdb4 397 Pfam PF00871 Acetokinase family 3 388 5.6E-172 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFK25_11730 eb5193a199145041e52ff76ee46dfdb4 397 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 202 219 - T 11-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFK25_11730 eb5193a199145041e52ff76ee46dfdb4 397 PIRSF PIRSF000722 1 397 6.8E-154 T 11-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFK25_11730 eb5193a199145041e52ff76ee46dfdb4 397 SUPERFAMILY SSF53067 1 194 2.91E-73 T 11-10-2018 AFK25_11730 eb5193a199145041e52ff76ee46dfdb4 397 Hamap MF_00020 Acetate kinase [ackA]. 1 397 200.039 T 11-10-2018 IPR004372 Acetate/propionate kinase GO:0006082|GO:0016301|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFK25_02890 f84962666101b2c97a82b15a632402e8 190 SUPERFAMILY SSF48498 81 189 4.45E-14 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFK25_02890 f84962666101b2c97a82b15a632402e8 190 ProSitePatterns PS01081 TetR-type HTH domain signature. 20 51 - T 11-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFK25_02890 f84962666101b2c97a82b15a632402e8 190 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 4.7E-17 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_02890 f84962666101b2c97a82b15a632402e8 190 Gene3D G3DSA:1.10.357.10 49 188 1.7E-20 T 11-10-2018 AFK25_02890 f84962666101b2c97a82b15a632402e8 190 Gene3D G3DSA:1.10.10.60 1 48 5.7E-18 T 11-10-2018 AFK25_02890 f84962666101b2c97a82b15a632402e8 190 SUPERFAMILY SSF46689 3 73 1.75E-17 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_02890 f84962666101b2c97a82b15a632402e8 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 1.4E-8 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_02890 f84962666101b2c97a82b15a632402e8 190 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 1.4E-8 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_10505 b93aaf0f95e5cfaef334cca7c2b2e1ab 265 Hamap MF_00662 Phosphatidylserine decarboxylase proenzyme [psd]. 7 259 38.437 T 11-10-2018 IPR033178 Phosphatidylserine decarboxylase, prokaryotic type 1 GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 AFK25_10505 b93aaf0f95e5cfaef334cca7c2b2e1ab 265 Pfam PF02666 Phosphatidylserine decarboxylase 59 256 2.3E-55 T 11-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 AFK25_10505 b93aaf0f95e5cfaef334cca7c2b2e1ab 265 TIGRFAM TIGR00163 PS_decarb: phosphatidylserine decarboxylase 47 211 1.1E-45 T 11-10-2018 IPR033177 Phosphatidylserine decarboxylase GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 AFK25_05470 0c5c02653d8121c2ebdbf6fee50b80e8 61 SUPERFAMILY SSF143800 1 60 8.83E-23 T 11-10-2018 IPR034704 L28p-like Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_05470 0c5c02653d8121c2ebdbf6fee50b80e8 61 Gene3D G3DSA:2.30.170.40 18 61 2.5E-19 T 11-10-2018 IPR037147 Ribosomal protein L28/L24 superfamily GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_05470 0c5c02653d8121c2ebdbf6fee50b80e8 61 TIGRFAM TIGR00009 L28: ribosomal protein bL28 1 55 4.2E-22 T 11-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_05470 0c5c02653d8121c2ebdbf6fee50b80e8 61 Hamap MF_00373 50S ribosomal protein L28 [rpmB]. 1 61 18.349 T 11-10-2018 IPR001383 Ribosomal protein L28 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_05470 0c5c02653d8121c2ebdbf6fee50b80e8 61 Pfam PF00830 Ribosomal L28 family 3 57 4.1E-21 T 11-10-2018 IPR026569 Ribosomal protein L28/L24 GO:0003735 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_02885 be370a16b5fd1c28d4c7501c8d03813f 472 Pfam PF01593 Flavin containing amine oxidoreductase 12 460 4.8E-67 T 11-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AFK25_02885 be370a16b5fd1c28d4c7501c8d03813f 472 SUPERFAMILY SSF51905 3 459 6.48E-55 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_02885 be370a16b5fd1c28d4c7501c8d03813f 472 Gene3D G3DSA:1.10.3110.10 107 200 2.4E-153 T 11-10-2018 AFK25_02885 be370a16b5fd1c28d4c7501c8d03813f 472 Gene3D G3DSA:3.50.50.60 6 451 2.4E-153 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_02885 be370a16b5fd1c28d4c7501c8d03813f 472 TIGRFAM TIGR00562 proto_IX_ox: protoporphyrinogen oxidase 2 463 4.4E-131 T 11-10-2018 IPR004572 Protoporphyrinogen oxidase GO:0004729|GO:0006779|GO:0055114 KEGG: 00860+1.3.3.4|MetaCyc: PWY-7159|Reactome: R-HSA-189451 AFK25_02885 be370a16b5fd1c28d4c7501c8d03813f 472 Gene3D G3DSA:3.90.660.20 41 409 2.4E-153 T 11-10-2018 AFK25_02885 be370a16b5fd1c28d4c7501c8d03813f 472 SUPERFAMILY SSF54373 303 410 8.34E-34 T 11-10-2018 AFK25_11140 6ea4b75f8f4285eea5fcfe91815ab2d5 552 SMART SM00382 89 267 6.4E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_11140 6ea4b75f8f4285eea5fcfe91815ab2d5 552 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 93 266 1.1E-18 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFK25_11140 6ea4b75f8f4285eea5fcfe91815ab2d5 552 ProSitePatterns PS01046 ATP-dependent serine proteases, lon family, serine active site. 442 450 - T 11-10-2018 IPR008268 Peptidase S16, active site GO:0004176|GO:0004252|GO:0006508 AFK25_11140 6ea4b75f8f4285eea5fcfe91815ab2d5 552 TIGRFAM TIGR02902 spore_lonB: ATP-dependent protease LonB 5 533 3.2E-279 T 11-10-2018 IPR014251 Sporulation protease LonB AFK25_11140 6ea4b75f8f4285eea5fcfe91815ab2d5 552 Gene3D G3DSA:3.40.50.300 122 264 4.1E-21 T 11-10-2018 AFK25_11140 6ea4b75f8f4285eea5fcfe91815ab2d5 552 Gene3D G3DSA:3.40.50.300 52 121 9.9E-12 T 11-10-2018 AFK25_11140 6ea4b75f8f4285eea5fcfe91815ab2d5 552 SUPERFAMILY SSF52540 55 328 1.71E-49 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_11140 6ea4b75f8f4285eea5fcfe91815ab2d5 552 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 343 533 2.9E-31 T 11-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 AFK25_11140 6ea4b75f8f4285eea5fcfe91815ab2d5 552 SUPERFAMILY SSF54211 351 534 2.54E-42 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFK25_11140 6ea4b75f8f4285eea5fcfe91815ab2d5 552 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 469 488 7.9E-31 T 11-10-2018 AFK25_11140 6ea4b75f8f4285eea5fcfe91815ab2d5 552 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 97 116 7.9E-31 T 11-10-2018 AFK25_11140 6ea4b75f8f4285eea5fcfe91815ab2d5 552 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 439 458 7.9E-31 T 11-10-2018 AFK25_11140 6ea4b75f8f4285eea5fcfe91815ab2d5 552 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 492 510 7.9E-31 T 11-10-2018 AFK25_11140 6ea4b75f8f4285eea5fcfe91815ab2d5 552 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 352 368 7.9E-31 T 11-10-2018 AFK25_11140 6ea4b75f8f4285eea5fcfe91815ab2d5 552 Gene3D G3DSA:3.30.230.10 342 547 2.1E-50 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFK25_05140 ba8ad17bd0d5ec24c93e1a619255c8ec 337 SUPERFAMILY SSF50156 122 193 1.86E-12 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 AFK25_05140 ba8ad17bd0d5ec24c93e1a619255c8ec 337 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 232 331 2.9E-10 T 11-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 AFK25_05140 ba8ad17bd0d5ec24c93e1a619255c8ec 337 Gene3D G3DSA:3.30.230.10 220 336 5.5E-18 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFK25_05140 ba8ad17bd0d5ec24c93e1a619255c8ec 337 Pfam PF13180 PDZ domain 126 192 2.6E-15 T 11-10-2018 IPR001478 PDZ domain GO:0005515 AFK25_05140 ba8ad17bd0d5ec24c93e1a619255c8ec 337 Gene3D G3DSA:2.30.42.10 123 219 3.3E-26 T 11-10-2018 AFK25_05140 ba8ad17bd0d5ec24c93e1a619255c8ec 337 SMART SM00228 119 186 5.7E-6 T 11-10-2018 IPR001478 PDZ domain GO:0005515 AFK25_05140 ba8ad17bd0d5ec24c93e1a619255c8ec 337 SUPERFAMILY SSF54211 173 333 3.79E-23 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFK25_08275 2176c72913ee9b2846abfdef002f70b1 382 SUPERFAMILY SSF51735 1 176 4.83E-22 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_08275 2176c72913ee9b2846abfdef002f70b1 382 Gene3D G3DSA:3.40.50.720 3 375 6.8E-115 T 11-10-2018 AFK25_08275 2176c72913ee9b2846abfdef002f70b1 382 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 129 375 2.8E-37 T 11-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 AFK25_08275 2176c72913ee9b2846abfdef002f70b1 382 Gene3D G3DSA:3.30.360.10 130 328 6.8E-115 T 11-10-2018 AFK25_08275 2176c72913ee9b2846abfdef002f70b1 382 SUPERFAMILY SSF55347 130 323 3.79E-39 T 11-10-2018 AFK25_08275 2176c72913ee9b2846abfdef002f70b1 382 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 3 125 1.5E-23 T 11-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 AFK25_07115 eb4fee58f7a295b8861d88b8d33731cd 258 SUPERFAMILY SSF81342 32 246 5.16E-39 T 11-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AFK25_07115 eb4fee58f7a295b8861d88b8d33731cd 258 TIGRFAM TIGR02125 CytB-hydogenase: Ni/Fe-hydrogenase, b-type cytochrome subunit 37 246 5.4E-55 T 11-10-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0009055|GO:0016021 AFK25_07115 eb4fee58f7a295b8861d88b8d33731cd 258 Pfam PF01292 Prokaryotic cytochrome b561 38 242 1.5E-30 T 11-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 AFK25_07115 eb4fee58f7a295b8861d88b8d33731cd 258 ProSitePatterns PS00882 Nickel-dependent hydrogenases b-type cytochrome subunit signature 1. 44 61 - T 11-10-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0009055|GO:0016021 AFK25_07115 eb4fee58f7a295b8861d88b8d33731cd 258 ProSitePatterns PS00883 Nickel-dependent hydrogenases b-type cytochrome subunit signature 2. 203 220 - T 11-10-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0009055|GO:0016021 AFK25_07115 eb4fee58f7a295b8861d88b8d33731cd 258 Gene3D G3DSA:1.20.950.20 27 232 4.7E-69 T 11-10-2018 AFK25_07115 eb4fee58f7a295b8861d88b8d33731cd 258 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 81 105 7.6E-31 T 11-10-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0009055|GO:0016021 AFK25_07115 eb4fee58f7a295b8861d88b8d33731cd 258 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 41 64 7.6E-31 T 11-10-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0009055|GO:0016021 AFK25_07115 eb4fee58f7a295b8861d88b8d33731cd 258 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 203 225 7.6E-31 T 11-10-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0009055|GO:0016021 AFK25_07115 eb4fee58f7a295b8861d88b8d33731cd 258 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 156 175 7.6E-31 T 11-10-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0009055|GO:0016021 AFK25_07115 eb4fee58f7a295b8861d88b8d33731cd 258 PRINTS PR00161 Nickel-dependent hydrogenase/B-type cytochrome signature 234 247 7.6E-31 T 11-10-2018 IPR000516 Nickel-dependent hydrogenase b-type cytochrome subunit GO:0005506|GO:0009055|GO:0016021 AFK25_07230 947f98a02e70367b2f247dbbaafe31c6 467 Gene3D G3DSA:3.30.1360.60 1 76 3.2E-26 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 AFK25_07230 947f98a02e70367b2f247dbbaafe31c6 467 TIGRFAM TIGR00826 EIIB_glc: PTS system, glucose-like IIB component 26 108 4.9E-21 T 11-10-2018 IPR001996 Phosphotransferase system, IIB component, type 1 GO:0008982|GO:0009401 AFK25_07230 947f98a02e70367b2f247dbbaafe31c6 467 TIGRFAM TIGR01992 PTS-IIBC-Tre: PTS system, trehalose-specific IIBC component 3 461 2.4E-204 T 11-10-2018 IPR011296 Phosphotransferase system, trehalose-specific IIBC component GO:0015574|GO:0015771|GO:0016021 KEGG: 00500+2.7.1.201 AFK25_07230 947f98a02e70367b2f247dbbaafe31c6 467 Pfam PF00367 phosphotransferase system, EIIB 7 39 6.6E-16 T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 AFK25_07230 947f98a02e70367b2f247dbbaafe31c6 467 SUPERFAMILY SSF55604 5 80 1.06E-21 T 11-10-2018 IPR036878 Glucose permease domain IIB GO:0008982|GO:0009401 AFK25_07230 947f98a02e70367b2f247dbbaafe31c6 467 Pfam PF02378 Phosphotransferase system, EIIC 109 405 9.6E-45 T 11-10-2018 IPR003352 Phosphotransferase system, EIIC GO:0008982|GO:0009401|GO:0016020 AFK25_07230 947f98a02e70367b2f247dbbaafe31c6 467 TIGRFAM TIGR01996 PTS-II-BC-sucr: PTS system, sucrose-specific IIBC component 3 460 2.2E-169 T 11-10-2018 IPR010973 Phosphotransferase system, sucrose-specific IIBC component GO:0008982|GO:0009401|GO:0016021 AFK25_07230 947f98a02e70367b2f247dbbaafe31c6 467 ProSitePatterns PS01035 PTS EIIB domains cysteine phosphorylation site signature. 17 34 - T 11-10-2018 IPR018113 Phosphotransferase system EIIB, cysteine phosphorylation site GO:0008982 AFK25_07910 6eeabc9a68b69e7805083b9bc05ef697 363 TIGRFAM TIGR02906 spore_CotS: spore coat protein, CotS family 40 353 1.6E-97 T 11-10-2018 IPR014255 Spore coat protein CotS AFK25_07910 6eeabc9a68b69e7805083b9bc05ef697 363 SUPERFAMILY SSF56112 18 315 1.41E-33 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily AFK25_07910 6eeabc9a68b69e7805083b9bc05ef697 363 Gene3D G3DSA:3.30.200.20 8 118 8.5E-29 T 11-10-2018 AFK25_07910 6eeabc9a68b69e7805083b9bc05ef697 363 Gene3D G3DSA:3.90.1200.10 124 350 1.1E-63 T 11-10-2018 AFK25_04445 e303215069b12afc96c45ea526dcd313 239 SMART SM00382 28 216 7.2E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_04445 e303215069b12afc96c45ea526dcd313 239 SUPERFAMILY SSF52540 3 223 3.66E-63 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_04445 e303215069b12afc96c45ea526dcd313 239 Gene3D G3DSA:3.40.50.300 1 235 4.5E-68 T 11-10-2018 AFK25_04445 e303215069b12afc96c45ea526dcd313 239 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_04445 e303215069b12afc96c45ea526dcd313 239 Pfam PF00005 ABC transporter 20 160 1.3E-33 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_12200 b396289b74b96d777db683b18b8807dc 327 Pfam PF01297 Zinc-uptake complex component A periplasmic 40 325 1.3E-73 T 11-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 AFK25_12200 b396289b74b96d777db683b18b8807dc 327 Gene3D G3DSA:3.40.50.1980 27 214 2.9E-56 T 11-10-2018 AFK25_12200 b396289b74b96d777db683b18b8807dc 327 PRINTS PR00691 Adhesin B signature 37 58 1.7E-5 T 11-10-2018 IPR006129 Adhesin B GO:0007155 AFK25_12200 b396289b74b96d777db683b18b8807dc 327 PRINTS PR00691 Adhesin B signature 81 100 1.7E-5 T 11-10-2018 IPR006129 Adhesin B GO:0007155 AFK25_12200 b396289b74b96d777db683b18b8807dc 327 PRINTS PR00691 Adhesin B signature 62 80 1.7E-5 T 11-10-2018 IPR006129 Adhesin B GO:0007155 AFK25_12200 b396289b74b96d777db683b18b8807dc 327 PRINTS PR00691 Adhesin B signature 261 278 1.7E-5 T 11-10-2018 IPR006129 Adhesin B GO:0007155 AFK25_12200 b396289b74b96d777db683b18b8807dc 327 SUPERFAMILY SSF53807 37 326 5.89E-82 T 11-10-2018 AFK25_12200 b396289b74b96d777db683b18b8807dc 327 PRINTS PR00690 Adhesin family signature 37 55 5.8E-8 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFK25_12200 b396289b74b96d777db683b18b8807dc 327 PRINTS PR00690 Adhesin family signature 68 81 5.8E-8 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFK25_12200 b396289b74b96d777db683b18b8807dc 327 PRINTS PR00690 Adhesin family signature 81 98 5.8E-8 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFK25_12200 b396289b74b96d777db683b18b8807dc 327 PRINTS PR00690 Adhesin family signature 265 283 5.8E-8 T 11-10-2018 IPR006128 Adhesion lipoprotein GO:0007155 AFK25_12200 b396289b74b96d777db683b18b8807dc 327 Gene3D G3DSA:3.40.50.1980 215 327 1.1E-40 T 11-10-2018 AFK25_07785 151f9e28483df03d53fdb29a7f7ec6c2 73 Gene3D G3DSA:1.20.1270.20 1 63 4.0E-22 T 11-10-2018 IPR016100 Prismane, alpha-bundle GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 AFK25_07785 151f9e28483df03d53fdb29a7f7ec6c2 73 Pfam PF03063 Prismane/CO dehydrogenase family 1 62 3.3E-13 T 11-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 AFK25_07785 151f9e28483df03d53fdb29a7f7ec6c2 73 SUPERFAMILY SSF56821 1 69 5.31E-16 T 11-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 AFK25_06345 43202a21fa9bb892535670a3a45d547e 293 Gene3D G3DSA:3.40.190.290 89 292 4.5E-40 T 11-10-2018 AFK25_06345 43202a21fa9bb892535670a3a45d547e 293 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 61 6.5E-18 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFK25_06345 43202a21fa9bb892535670a3a45d547e 293 SUPERFAMILY SSF46785 3 84 4.44E-21 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_06345 43202a21fa9bb892535670a3a45d547e 293 Pfam PF03466 LysR substrate binding domain 89 290 4.0E-44 T 11-10-2018 IPR005119 LysR, substrate-binding AFK25_06345 43202a21fa9bb892535670a3a45d547e 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 38 49 6.1E-8 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFK25_06345 43202a21fa9bb892535670a3a45d547e 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 17 28 6.1E-8 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFK25_06345 43202a21fa9bb892535670a3a45d547e 293 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 28 38 6.1E-8 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFK25_06345 43202a21fa9bb892535670a3a45d547e 293 SUPERFAMILY SSF53850 88 291 1.48E-42 T 11-10-2018 AFK25_06345 43202a21fa9bb892535670a3a45d547e 293 Gene3D G3DSA:1.10.10.10 1 69 8.2E-24 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_05630 1612432d9dcc368f573ab4165e1d00e5 300 SUPERFAMILY SSF56349 9 292 9.12E-57 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFK25_05630 1612432d9dcc368f573ab4165e1d00e5 300 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 11 300 1.1E-99 T 11-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 AFK25_05630 1612432d9dcc368f573ab4165e1d00e5 300 Gene3D G3DSA:1.10.443.10 112 294 5.9E-61 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFK25_05630 1612432d9dcc368f573ab4165e1d00e5 300 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 8 91 7.0E-23 T 11-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFK25_05630 1612432d9dcc368f573ab4165e1d00e5 300 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 11 300 5.8E-110 T 11-10-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007059|GO:0015074|GO:0051301 AFK25_05630 1612432d9dcc368f573ab4165e1d00e5 300 Pfam PF00589 Phage integrase family 113 286 3.2E-48 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFK25_05630 1612432d9dcc368f573ab4165e1d00e5 300 Gene3D G3DSA:1.10.150.130 6 99 4.9E-26 T 11-10-2018 IPR010998 Integrase/recombinase, N-terminal AFK25_05630 1612432d9dcc368f573ab4165e1d00e5 300 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 6 300 57.356 T 11-10-2018 IPR023009 Tyrosine recombinase XerC/XerD AFK25_06710 175fd1b4d7f3ec90870c0d21e56c046f 263 SUPERFAMILY SSF55021 5 75 1.79E-9 T 11-10-2018 AFK25_06710 175fd1b4d7f3ec90870c0d21e56c046f 263 PIRSF PIRSF021288 1 262 8.5E-149 T 11-10-2018 IPR016784 Uncharacterised protein UCP021288 with ACT domain AFK25_06710 175fd1b4d7f3ec90870c0d21e56c046f 263 Pfam PF11868 Protein of unknown function (DUF3388) 72 260 1.4E-107 T 11-10-2018 IPR024514 Domain of unknown function DUF3388 AFK25_03985 412c6a9fbf05c6c4dcf29add647ae005 90 Pfam PF13143 Protein of unknown function (DUF3986) 2 87 3.6E-32 T 11-10-2018 IPR025047 Protein of unknown function DUF3986 AFK25_12265 f9a46c1eabf129aa7db995a5454e311b 272 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 5 271 56.516 T 11-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 AFK25_12265 f9a46c1eabf129aa7db995a5454e311b 272 SUPERFAMILY SSF52096 5 268 6.69E-82 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFK25_12265 f9a46c1eabf129aa7db995a5454e311b 272 Gene3D G3DSA:3.90.226.10 1 209 2.7E-81 T 11-10-2018 AFK25_12265 f9a46c1eabf129aa7db995a5454e311b 272 Gene3D G3DSA:1.10.12.10 210 260 4.8E-29 T 11-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AFK25_12265 f9a46c1eabf129aa7db995a5454e311b 272 Pfam PF00378 Enoyl-CoA hydratase/isomerase 17 267 2.4E-93 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFK25_12265 f9a46c1eabf129aa7db995a5454e311b 272 TIGRFAM TIGR01929 menB: naphthoate synthase 11 268 3.2E-133 T 11-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 AFK25_12265 f9a46c1eabf129aa7db995a5454e311b 272 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 110 130 - T 11-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 AFK25_10020 f44076a234472eb2e9af14760e39c700 145 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 4 25 1.1E-6 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_10020 f44076a234472eb2e9af14760e39c700 145 SUPERFAMILY SSF54523 6 74 9.42E-9 T 11-10-2018 AFK25_10020 f44076a234472eb2e9af14760e39c700 145 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 23 4.7E-6 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_10020 f44076a234472eb2e9af14760e39c700 145 PIRSF PIRSF021292 1 145 3.1E-42 T 11-10-2018 IPR016785 ComG operon protein 4 GO:0030420 AFK25_10020 f44076a234472eb2e9af14760e39c700 145 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 4 24 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_10245 36e13f79aaac4b14ebf9c6180bdfbf3e 425 SMART SM00487 19 220 8.5E-53 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFK25_10245 36e13f79aaac4b14ebf9c6180bdfbf3e 425 Gene3D G3DSA:3.40.50.300 1 212 7.8E-70 T 11-10-2018 AFK25_10245 36e13f79aaac4b14ebf9c6180bdfbf3e 425 SMART SM00490 256 337 2.6E-29 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_10245 36e13f79aaac4b14ebf9c6180bdfbf3e 425 Pfam PF00271 Helicase conserved C-terminal domain 230 337 2.0E-26 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_10245 36e13f79aaac4b14ebf9c6180bdfbf3e 425 Gene3D G3DSA:3.40.50.300 213 370 9.9E-43 T 11-10-2018 AFK25_10245 36e13f79aaac4b14ebf9c6180bdfbf3e 425 Hamap MF_01494 DEAD-box ATP-dependent RNA helicase CshB [cshB]. 1 425 47.564 T 11-10-2018 IPR030881 DEAD-box ATP-dependent RNA helicase CshB GO:0004386|GO:0009409 AFK25_10245 36e13f79aaac4b14ebf9c6180bdfbf3e 425 Pfam PF00270 DEAD/DEAH box helicase 24 192 2.0E-42 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFK25_10245 36e13f79aaac4b14ebf9c6180bdfbf3e 425 SUPERFAMILY SSF52540 68 358 4.11E-66 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_09205 5cfa7fe67f9d79c762dae4682a3245b4 348 SUPERFAMILY SSF81345 13 339 1.57E-76 T 11-10-2018 IPR037294 ABC transporter, BtuC-like AFK25_09205 5cfa7fe67f9d79c762dae4682a3245b4 348 Gene3D G3DSA:1.10.3470.10 6 346 3.0E-95 T 11-10-2018 IPR037294 ABC transporter, BtuC-like AFK25_09205 5cfa7fe67f9d79c762dae4682a3245b4 348 Pfam PF01032 FecCD transport family 21 339 1.5E-88 T 11-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AFK25_10225 eafdba15c8dab172cd78d09ce218a138 251 SUPERFAMILY SSF52540 3 225 7.17E-59 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_10225 eafdba15c8dab172cd78d09ce218a138 251 Gene3D G3DSA:3.40.50.300 1 242 7.8E-67 T 11-10-2018 AFK25_10225 eafdba15c8dab172cd78d09ce218a138 251 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_10225 eafdba15c8dab172cd78d09ce218a138 251 Pfam PF00005 ABC transporter 20 168 6.6E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_10225 eafdba15c8dab172cd78d09ce218a138 251 SMART SM00382 29 214 3.2E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_08515 acbb5ac332035de8d01e5aab3b9ef859 152 Gene3D G3DSA:1.20.120.330 23 144 9.4E-26 T 11-10-2018 AFK25_08515 acbb5ac332035de8d01e5aab3b9ef859 152 TIGRFAM TIGR01987 HI0074: nucleotidyltransferase substrate binding protein, HI0074 family 34 141 5.9E-18 T 11-10-2018 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 AFK25_08515 acbb5ac332035de8d01e5aab3b9ef859 152 Pfam PF08780 Nucleotidyltransferase substrate binding protein like 25 142 4.9E-22 T 11-10-2018 IPR010235 Nucleotidyltransferase substrate binding protein, HI0074 AFK25_08515 acbb5ac332035de8d01e5aab3b9ef859 152 SUPERFAMILY SSF81593 21 140 2.39E-30 T 11-10-2018 AFK25_04400 7899bc9e8ac7558c9cbc9dd1252953f4 407 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 124 403 3.2E-42 T 11-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFK25_04400 7899bc9e8ac7558c9cbc9dd1252953f4 407 Gene3D G3DSA:3.30.70.150 1 118 1.0E-29 T 11-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFK25_04400 7899bc9e8ac7558c9cbc9dd1252953f4 407 TIGRFAM TIGR03332 salvage_mtnW: 2,3-diketo-5-methylthiopentyl-1-phosphate enolase 2 404 9.3E-218 T 11-10-2018 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 AFK25_04400 7899bc9e8ac7558c9cbc9dd1252953f4 407 SUPERFAMILY SSF51649 118 405 7.33E-87 T 11-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFK25_04400 7899bc9e8ac7558c9cbc9dd1252953f4 407 Hamap MF_01679 2,3-diketo-5-methylthiopentyl-1-phosphate enolase [mtnW]. 1 404 59.166 T 11-10-2018 IPR017717 2,3-diketo-5-methylthiopentyl-1-phosphate enolase GO:0000287|GO:0019509|GO:0043715 KEGG: 00270+5.3.2.5|MetaCyc: PWY-4361 AFK25_04400 7899bc9e8ac7558c9cbc9dd1252953f4 407 Gene3D G3DSA:3.20.20.110 119 407 2.0E-100 T 11-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFK25_04400 7899bc9e8ac7558c9cbc9dd1252953f4 407 SUPERFAMILY SSF54966 1 118 1.41E-29 T 11-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AFK25_03300 c3b2481c45db3b3ab1908485e6b5d4ec 249 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 215 1.1E-51 T 11-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFK25_03300 c3b2481c45db3b3ab1908485e6b5d4ec 249 SUPERFAMILY SSF53790 2 247 7.72E-83 T 11-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFK25_03300 c3b2481c45db3b3ab1908485e6b5d4ec 249 Gene3D G3DSA:3.30.950.10 120 249 3.2E-49 T 11-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFK25_03300 c3b2481c45db3b3ab1908485e6b5d4ec 249 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 84 117 - T 11-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFK25_03300 c3b2481c45db3b3ab1908485e6b5d4ec 249 Gene3D G3DSA:3.40.1010.10 2 119 7.4E-44 T 11-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFK25_03300 c3b2481c45db3b3ab1908485e6b5d4ec 249 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 4 239 1.3E-94 T 11-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFK25_13170 78fdd74a38a09a3cf6d95dcfa278356b 349 Gene3D G3DSA:3.20.20.70 2 277 8.5E-95 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_13170 78fdd74a38a09a3cf6d95dcfa278356b 349 Gene3D G3DSA:3.90.1210.10 281 348 1.3E-25 T 11-10-2018 AFK25_13170 78fdd74a38a09a3cf6d95dcfa278356b 349 SUPERFAMILY SSF51569 2 303 9.4E-94 T 11-10-2018 AFK25_13170 78fdd74a38a09a3cf6d95dcfa278356b 349 TIGRFAM TIGR03586 PseI: pseudaminic acid synthase 15 343 3.9E-160 T 11-10-2018 IPR020030 Pseudaminic acid biosynthesis, PseI KEGG: 00520+2.5.1.97|MetaCyc: PWY-6143 AFK25_13170 78fdd74a38a09a3cf6d95dcfa278356b 349 SMART SM00858 291 349 9.9E-13 T 11-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 AFK25_13170 78fdd74a38a09a3cf6d95dcfa278356b 349 SUPERFAMILY SSF51269 287 348 4.71E-21 T 11-10-2018 IPR036732 Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily Reactome: R-HSA-4085001 AFK25_13170 78fdd74a38a09a3cf6d95dcfa278356b 349 Pfam PF03102 NeuB family 36 277 1.2E-91 T 11-10-2018 IPR013132 N-acetylneuraminic acid synthase, N-terminal GO:0016051 Reactome: R-HSA-4085001 AFK25_13170 78fdd74a38a09a3cf6d95dcfa278356b 349 Pfam PF08666 SAF domain 292 348 4.7E-15 T 11-10-2018 IPR013974 SAF domain Reactome: R-HSA-4085001 AFK25_03735 4f8b2692df61b1cd994022fd3caeb49a 230 Gene3D G3DSA:3.40.50.1820 1 229 3.6E-39 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold AFK25_03735 4f8b2692df61b1cd994022fd3caeb49a 230 SUPERFAMILY SSF53474 4 225 3.25E-28 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold AFK25_03735 4f8b2692df61b1cd994022fd3caeb49a 230 Pfam PF00756 Putative esterase 8 224 9.7E-42 T 11-10-2018 IPR000801 Putative esterase Reactome: R-HSA-156590 AFK25_14265 5aeca511015a0287ef12ecc77feee5ab 217 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 215 2.7E-22 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_14265 5aeca511015a0287ef12ecc77feee5ab 217 SUPERFAMILY SSF161098 13 201 1.96E-49 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_14265 5aeca511015a0287ef12ecc77feee5ab 217 Gene3D G3DSA:1.10.3720.10 1 216 2.3E-61 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_14265 5aeca511015a0287ef12ecc77feee5ab 217 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 13 110 1.7E-24 T 11-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 AFK25_01795 6ca9ca7c9cfc7307830dab1515eb0ee6 374 Pfam PF04055 Radical SAM superfamily 36 176 9.1E-11 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFK25_01795 6ca9ca7c9cfc7307830dab1515eb0ee6 374 Pfam PF08756 YfkB-like domain 220 370 4.9E-80 T 11-10-2018 IPR014866 YfkB-like domain AFK25_01795 6ca9ca7c9cfc7307830dab1515eb0ee6 374 Pfam PF13353 4Fe-4S single cluster domain 40 134 5.6E-6 T 11-10-2018 AFK25_01795 6ca9ca7c9cfc7307830dab1515eb0ee6 374 TIGRFAM TIGR04478 rSAM_YfkAB: radical SAM/CxCxxxxC motif protein YfkAB 8 370 5.0E-197 T 11-10-2018 IPR031004 Radical SAM/CxCxxxxC motif protein YfkAB AFK25_01795 6ca9ca7c9cfc7307830dab1515eb0ee6 374 SUPERFAMILY SSF102114 32 327 2.35E-26 T 11-10-2018 AFK25_01795 6ca9ca7c9cfc7307830dab1515eb0ee6 374 Gene3D G3DSA:3.20.20.70 23 292 6.9E-22 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_02810 3a0fb6d08530cc2156401635a8a641ee 173 Pfam PF17099 Tryptophan transporter TrpP 2 165 6.6E-48 T 11-10-2018 IPR031360 Tryptophan transporter TrpP AFK25_02810 3a0fb6d08530cc2156401635a8a641ee 173 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 162 4.0E-45 T 11-10-2018 AFK25_04825 900edb76adea489413bbf50f09bf43ed 377 SUPERFAMILY SSF53187 2 364 1.7E-67 T 11-10-2018 AFK25_04825 900edb76adea489413bbf50f09bf43ed 377 PIRSF PIRSF005962 1 372 6.5E-106 T 11-10-2018 IPR017439 Amidohydrolase GO:0016787 AFK25_04825 900edb76adea489413bbf50f09bf43ed 377 Gene3D G3DSA:3.40.630.10 3 354 8.4E-118 T 11-10-2018 AFK25_04825 900edb76adea489413bbf50f09bf43ed 377 Pfam PF01546 Peptidase family M20/M25/M40 63 365 6.5E-27 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 AFK25_04825 900edb76adea489413bbf50f09bf43ed 377 SUPERFAMILY SSF55031 174 283 5.36E-28 T 11-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain AFK25_04825 900edb76adea489413bbf50f09bf43ed 377 Pfam PF07687 Peptidase dimerisation domain 178 268 5.6E-8 T 11-10-2018 IPR011650 Peptidase M20, dimerisation domain AFK25_04825 900edb76adea489413bbf50f09bf43ed 377 Gene3D G3DSA:3.30.70.360 169 283 8.4E-118 T 11-10-2018 AFK25_04825 900edb76adea489413bbf50f09bf43ed 377 Hamap MF_01692 N-acetyldiaminopimelate deacetylase. 1 368 62.274 T 11-10-2018 IPR023905 Acetyldiaminopimelate deacetylase GO:0009089|GO:0050118 KEGG: 00300+3.5.1.47|MetaCyc: PWY-2941 AFK25_04825 900edb76adea489413bbf50f09bf43ed 377 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 3 357 2.7E-88 T 11-10-2018 IPR017439 Amidohydrolase GO:0016787 AFK25_05745 0eb2edbf847762d5a537acad08fcfef9 89 PIRSF PIRSF004669 1 89 5.9E-33 T 11-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFK25_05745 0eb2edbf847762d5a537acad08fcfef9 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 54 76 3.3E-22 T 11-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFK25_05745 0eb2edbf847762d5a537acad08fcfef9 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 18 39 3.3E-22 T 11-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFK25_05745 0eb2edbf847762d5a537acad08fcfef9 89 PRINTS PR00952 Type III secretion system inner membrane Q protein family signature 39 54 3.3E-22 T 11-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFK25_05745 0eb2edbf847762d5a537acad08fcfef9 89 Pfam PF01313 Bacterial export proteins, family 3 6 77 3.5E-29 T 11-10-2018 IPR002191 Bacterial export protein family 3 GO:0009306|GO:0016020 AFK25_05745 0eb2edbf847762d5a537acad08fcfef9 89 TIGRFAM TIGR01402 fliQ: flagellar biosynthetic protein FliQ 1 87 6.8E-33 T 11-10-2018 IPR006305 Flagellar biosynthesis protein FliQ GO:0016021|GO:0044780 AFK25_04435 8bd39fb52875e0aa74801750542187c1 172 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 50 170 8.4E-28 T 11-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 AFK25_04435 8bd39fb52875e0aa74801750542187c1 172 SUPERFAMILY SSF50118 49 172 1.7E-22 T 11-10-2018 AFK25_04435 8bd39fb52875e0aa74801750542187c1 172 Gene3D G3DSA:2.30.30.110 36 172 7.8E-33 T 11-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor AFK25_14510 9011af8ee2b9c1927fd4741b90f51626 182 Hamap MF_00658 Ribosomal RNA large subunit methyltransferase H [rlmH]. 24 182 30.979 T 11-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 AFK25_14510 9011af8ee2b9c1927fd4741b90f51626 182 SUPERFAMILY SSF75217 25 180 6.54E-60 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases AFK25_14510 9011af8ee2b9c1927fd4741b90f51626 182 Pfam PF02590 Predicted SPOUT methyltransferase 25 181 6.1E-60 T 11-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 AFK25_14510 9011af8ee2b9c1927fd4741b90f51626 182 TIGRFAM TIGR00246 tRNA_RlmH_YbeA: rRNA large subunit m3Psi methyltransferase RlmH 24 182 1.4E-67 T 11-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 AFK25_14510 9011af8ee2b9c1927fd4741b90f51626 182 Gene3D G3DSA:3.40.1280.10 24 182 1.5E-67 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFK25_14510 9011af8ee2b9c1927fd4741b90f51626 182 PIRSF PIRSF004505 24 182 3.9E-54 T 11-10-2018 IPR003742 RNA methyltransferase RlmH GO:0005737|GO:0006364|GO:0008168 AFK25_05435 b2bb8260fc75549093d1794a22e9f0b8 349 PIRSF PIRSF006004 1 349 5.5E-142 T 11-10-2018 IPR004383 Ribosomal RNA large subunit methyltransferase RlmN/Cfr GO:0005737|GO:0006364|GO:0008173 AFK25_05435 b2bb8260fc75549093d1794a22e9f0b8 349 Pfam PF13394 4Fe-4S single cluster domain 110 213 5.2E-6 T 11-10-2018 AFK25_05435 b2bb8260fc75549093d1794a22e9f0b8 349 Gene3D G3DSA:3.20.20.70 66 329 1.3E-102 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_05435 b2bb8260fc75549093d1794a22e9f0b8 349 Hamap MF_01849 Dual-specificity RNA methyltransferase RlmN [rlmN]. 2 344 75.096 T 11-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 AFK25_05435 b2bb8260fc75549093d1794a22e9f0b8 349 TIGRFAM TIGR00048 rRNA_mod_RlmN: 23S rRNA (adenine(2503)-C(2))-methyltransferase 1 348 3.7E-165 T 11-10-2018 IPR027492 Dual-specificity RNA methyltransferase RlmN GO:0030488|GO:0070475 AFK25_05435 b2bb8260fc75549093d1794a22e9f0b8 349 SUPERFAMILY SSF102114 85 308 3.14E-14 T 11-10-2018 AFK25_05435 b2bb8260fc75549093d1794a22e9f0b8 349 Gene3D G3DSA:1.10.150.530 2 63 6.7E-24 T 11-10-2018 AFK25_05435 b2bb8260fc75549093d1794a22e9f0b8 349 Pfam PF04055 Radical SAM superfamily 105 275 4.9E-18 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFK25_00690 abaca16becb71016edc91f2390f7dff9 166 Gene3D G3DSA:3.30.160.20 1 73 8.5E-36 T 11-10-2018 AFK25_00690 abaca16becb71016edc91f2390f7dff9 166 Pfam PF00333 Ribosomal protein S5, N-terminal domain 11 75 5.1E-33 T 11-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 AFK25_00690 abaca16becb71016edc91f2390f7dff9 166 ProSitePatterns PS00585 Ribosomal protein S5 signature. 28 60 - T 11-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site AFK25_00690 abaca16becb71016edc91f2390f7dff9 166 TIGRFAM TIGR01021 rpsE_bact: ribosomal protein uS5 9 163 2.3E-73 T 11-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFK25_00690 abaca16becb71016edc91f2390f7dff9 166 SUPERFAMILY SSF54768 8 76 1.88E-25 T 11-10-2018 AFK25_00690 abaca16becb71016edc91f2390f7dff9 166 SUPERFAMILY SSF54211 80 159 8.85E-27 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFK25_00690 abaca16becb71016edc91f2390f7dff9 166 Gene3D G3DSA:3.30.230.10 74 166 1.4E-37 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFK25_00690 abaca16becb71016edc91f2390f7dff9 166 Pfam PF03719 Ribosomal protein S5, C-terminal domain 87 157 2.7E-31 T 11-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 AFK25_00690 abaca16becb71016edc91f2390f7dff9 166 Hamap MF_01307_B 30S ribosomal protein S5 [rpsE]. 1 163 37.502 T 11-10-2018 IPR005712 Ribosomal protein S5, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFK25_14620 580979e1892de97ede62c00cfd6781df 287 SUPERFAMILY SSF110849 25 116 1.36E-29 T 11-10-2018 IPR036086 ParB/Sulfiredoxin superfamily AFK25_14620 580979e1892de97ede62c00cfd6781df 287 SMART SM00470 25 114 3.1E-37 T 11-10-2018 IPR003115 ParB/Sulfiredoxin AFK25_14620 580979e1892de97ede62c00cfd6781df 287 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 22 198 5.1E-66 T 11-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 AFK25_14620 580979e1892de97ede62c00cfd6781df 287 Gene3D G3DSA:3.90.1530.30 38 100 2.6E-27 T 11-10-2018 AFK25_14620 580979e1892de97ede62c00cfd6781df 287 SUPERFAMILY SSF109709 106 217 2.51E-36 T 11-10-2018 AFK25_14620 580979e1892de97ede62c00cfd6781df 287 Gene3D G3DSA:1.10.10.2830 101 215 2.8E-39 T 11-10-2018 AFK25_14620 580979e1892de97ede62c00cfd6781df 287 Pfam PF02195 ParB-like nuclease domain 26 113 1.4E-27 T 11-10-2018 IPR003115 ParB/Sulfiredoxin AFK25_05215 d205c72521eb83cb81062182bf9bf32a 444 TIGRFAM TIGR01087 murD: UDP-N-acetylmuramoylalanine--D-glutamate ligase 6 441 2.1E-136 T 11-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFK25_05215 d205c72521eb83cb81062182bf9bf32a 444 Gene3D G3DSA:3.90.190.20 309 442 1.9E-43 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFK25_05215 d205c72521eb83cb81062182bf9bf32a 444 SUPERFAMILY SSF53244 304 443 2.56E-44 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFK25_05215 d205c72521eb83cb81062182bf9bf32a 444 Pfam PF02875 Mur ligase family, glutamate ligase domain 305 371 1.9E-9 T 11-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 AFK25_05215 d205c72521eb83cb81062182bf9bf32a 444 Gene3D G3DSA:3.40.1190.10 96 302 9.5E-67 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFK25_05215 d205c72521eb83cb81062182bf9bf32a 444 Pfam PF08245 Mur ligase middle domain 111 285 4.5E-37 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 AFK25_05215 d205c72521eb83cb81062182bf9bf32a 444 Hamap MF_00639 UDP-N-acetylmuramoylalanine--D-glutamate ligase [murD]. 5 443 36.728 T 11-10-2018 IPR005762 UDP-N-acetylmuramoylalanine-D-glutamate ligase GO:0005524|GO:0005737|GO:0008360|GO:0008764|GO:0051301 KEGG: 00471+6.3.2.9|KEGG: 00550+6.3.2.9|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFK25_05215 d205c72521eb83cb81062182bf9bf32a 444 SUPERFAMILY SSF51984 5 94 1.96E-17 T 11-10-2018 AFK25_05215 d205c72521eb83cb81062182bf9bf32a 444 SUPERFAMILY SSF53623 97 302 8.5E-56 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFK25_05215 d205c72521eb83cb81062182bf9bf32a 444 Gene3D G3DSA:3.40.50.720 5 89 6.5E-29 T 11-10-2018 AFK25_10210 bc305539ccccfa6240aa7ce230aa3b7b 191 PIRSF PIRSF021362 3 190 2.5E-72 T 11-10-2018 IPR009206 Nucleotidase, putative AFK25_10210 bc305539ccccfa6240aa7ce230aa3b7b 191 SUPERFAMILY SSF56784 5 163 1.48E-16 T 11-10-2018 IPR036412 HAD-like superfamily AFK25_10210 bc305539ccccfa6240aa7ce230aa3b7b 191 Gene3D G3DSA:3.40.50.1000 2 157 9.4E-10 T 11-10-2018 IPR023214 HAD superfamily AFK25_03210 8d9ad99af2cec6e47f61eb0a736a0966 344 Pfam PF13377 Periplasmic binding protein-like domain 175 336 6.6E-39 T 11-10-2018 AFK25_03210 8d9ad99af2cec6e47f61eb0a736a0966 344 Gene3D G3DSA:1.10.260.40 1 60 7.3E-25 T 11-10-2018 AFK25_03210 8d9ad99af2cec6e47f61eb0a736a0966 344 Gene3D G3DSA:3.40.50.2300 76 328 3.3E-87 T 11-10-2018 AFK25_03210 8d9ad99af2cec6e47f61eb0a736a0966 344 Gene3D G3DSA:3.40.50.2300 167 330 3.3E-87 T 11-10-2018 AFK25_03210 8d9ad99af2cec6e47f61eb0a736a0966 344 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 49 2.0E-20 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_03210 8d9ad99af2cec6e47f61eb0a736a0966 344 SUPERFAMILY SSF47413 2 60 1.04E-18 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFK25_03210 8d9ad99af2cec6e47f61eb0a736a0966 344 SMART SM00354 2 72 5.1E-33 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_03210 8d9ad99af2cec6e47f61eb0a736a0966 344 SUPERFAMILY SSF53822 62 337 1.99E-82 T 11-10-2018 IPR028082 Periplasmic binding protein-like I AFK25_00030 e8ea02a65ffafab2a5cde9d98fa1d6d4 819 Gene3D G3DSA:3.30.1360.40 233 329 1.2E-223 T 11-10-2018 AFK25_00030 e8ea02a65ffafab2a5cde9d98fa1d6d4 819 SMART SM00434 8 461 9.3E-302 T 11-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFK25_00030 e8ea02a65ffafab2a5cde9d98fa1d6d4 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 502 548 1.5E-14 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFK25_00030 e8ea02a65ffafab2a5cde9d98fa1d6d4 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 705 752 3.0E-15 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFK25_00030 e8ea02a65ffafab2a5cde9d98fa1d6d4 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 551 599 2.2E-8 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFK25_00030 e8ea02a65ffafab2a5cde9d98fa1d6d4 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 756 793 2.1E-10 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFK25_00030 e8ea02a65ffafab2a5cde9d98fa1d6d4 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 656 702 6.4E-13 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFK25_00030 e8ea02a65ffafab2a5cde9d98fa1d6d4 819 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 609 651 2.1E-7 T 11-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AFK25_00030 e8ea02a65ffafab2a5cde9d98fa1d6d4 819 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 5 803 0.0 T 11-10-2018 AFK25_00030 e8ea02a65ffafab2a5cde9d98fa1d6d4 819 Gene3D G3DSA:1.10.268.10 366 455 1.2E-223 T 11-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFK25_00030 e8ea02a65ffafab2a5cde9d98fa1d6d4 819 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 29 468 6.0E-167 T 11-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AFK25_00030 e8ea02a65ffafab2a5cde9d98fa1d6d4 819 SUPERFAMILY SSF101904 496 814 3.27E-114 T 11-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal AFK25_00030 e8ea02a65ffafab2a5cde9d98fa1d6d4 819 Gene3D G3DSA:2.120.10.90 493 805 3.5E-128 T 11-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal AFK25_00030 e8ea02a65ffafab2a5cde9d98fa1d6d4 819 SUPERFAMILY SSF56719 27 484 1.2E-186 T 11-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AFK25_00030 e8ea02a65ffafab2a5cde9d98fa1d6d4 819 Gene3D G3DSA:3.90.199.10 29 482 1.2E-223 T 11-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 AFK25_00030 e8ea02a65ffafab2a5cde9d98fa1d6d4 819 Hamap MF_01897 DNA gyrase subunit A [gyrA]. 2 807 25.219 T 11-10-2018 IPR005743 DNA gyrase, subunit A GO:0003677|GO:0003918|GO:0005524|GO:0005694|GO:0006265 AFK25_09015 91d161ae06aa9bf4ee7ce614f9a79544 193 SUPERFAMILY SSF69593 4 191 5.1E-53 T 11-10-2018 AFK25_09015 91d161ae06aa9bf4ee7ce614f9a79544 193 Pfam PF01553 Acyltransferase 20 144 1.4E-24 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFK25_09015 91d161ae06aa9bf4ee7ce614f9a79544 193 SMART SM00563 35 147 2.5E-36 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFK25_12125 0781ec57fad8e564958f9248200b25f5 323 SUPERFAMILY SSF54106 170 214 2.49E-11 T 11-10-2018 AFK25_12125 0781ec57fad8e564958f9248200b25f5 323 SMART SM00701 15 141 4.6E-5 T 11-10-2018 IPR006619 Peptidoglycan recognition protein family domain, metazoa/bacteria GO:0008270|GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFK25_12125 0781ec57fad8e564958f9248200b25f5 323 Pfam PF01510 N-acetylmuramoyl-L-alanine amidase 34 149 3.3E-18 T 11-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFK25_12125 0781ec57fad8e564958f9248200b25f5 323 Gene3D G3DSA:3.40.80.10 30 167 3.2E-33 T 11-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFK25_12125 0781ec57fad8e564958f9248200b25f5 323 Pfam PF01471 Putative peptidoglycan binding domain 257 311 5.4E-5 T 11-10-2018 IPR002477 Peptidoglycan binding-like AFK25_12125 0781ec57fad8e564958f9248200b25f5 323 SUPERFAMILY SSF47090 249 314 1.26E-9 T 11-10-2018 IPR036365 PGBD-like superfamily AFK25_12125 0781ec57fad8e564958f9248200b25f5 323 Gene3D G3DSA:1.10.101.10 244 323 5.0E-14 T 11-10-2018 IPR036366 PGBD superfamily Reactome: R-HSA-1442490|Reactome: R-HSA-1474228 AFK25_12125 0781ec57fad8e564958f9248200b25f5 323 Pfam PF01476 LysM domain 172 214 8.3E-14 T 11-10-2018 IPR018392 LysM domain AFK25_12125 0781ec57fad8e564958f9248200b25f5 323 Gene3D G3DSA:3.10.350.10 170 215 1.6E-17 T 11-10-2018 IPR036779 LysM domain superfamily AFK25_12125 0781ec57fad8e564958f9248200b25f5 323 SMART SM00257 171 215 2.4E-15 T 11-10-2018 IPR018392 LysM domain AFK25_12125 0781ec57fad8e564958f9248200b25f5 323 SUPERFAMILY SSF55846 33 159 1.07E-29 T 11-10-2018 IPR036505 N-acetylmuramoyl-L-alanine amidase/PGRP domain superfamily GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFK25_12125 0781ec57fad8e564958f9248200b25f5 323 SMART SM00644 22 150 2.5E-10 T 11-10-2018 IPR002502 N-acetylmuramoyl-L-alanine amidase domain GO:0008745|GO:0009253 Reactome: R-HSA-6803157 AFK25_14225 d4409585de33db87e6fa6d4440974100 479 Gene3D G3DSA:2.115.10.20 1 353 3.6E-117 T 11-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFK25_14225 d4409585de33db87e6fa6d4440974100 479 SUPERFAMILY SSF49899 336 476 4.19E-19 T 11-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AFK25_14225 d4409585de33db87e6fa6d4440974100 479 SUPERFAMILY SSF75005 25 337 1.88E-113 T 11-10-2018 IPR023296 Glycosyl hydrolase, five-bladed beta-propellor domain superfamily AFK25_14225 d4409585de33db87e6fa6d4440974100 479 SMART SM00640 34 444 1.3E-146 T 11-10-2018 IPR001362 Glycoside hydrolase, family 32 GO:0004553|GO:0005975 AFK25_14225 d4409585de33db87e6fa6d4440974100 479 ProSitePatterns PS00609 Glycosyl hydrolases family 32 active site. 34 47 - T 11-10-2018 IPR018053 Glycoside hydrolase, family 32, active site GO:0004553|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 AFK25_14225 d4409585de33db87e6fa6d4440974100 479 Pfam PF00251 Glycosyl hydrolases family 32 N-terminal domain 34 336 1.8E-107 T 11-10-2018 IPR013148 Glycosyl hydrolase family 32, N-terminal AFK25_14225 d4409585de33db87e6fa6d4440974100 479 TIGRFAM TIGR01322 scrB_fam: sucrose-6-phosphate hydrolase 18 454 5.4E-172 T 11-10-2018 IPR006232 Sucrose-6-phosphate hydrolase GO:0004564|GO:0005737|GO:0005975 KEGG: 00052+3.2.1.26|KEGG: 00500+3.2.1.26 AFK25_14225 d4409585de33db87e6fa6d4440974100 479 Gene3D G3DSA:2.60.120.560 376 479 1.3E-13 T 11-10-2018 AFK25_14225 d4409585de33db87e6fa6d4440974100 479 Pfam PF08244 Glycosyl hydrolases family 32 C terminal 341 474 3.1E-13 T 11-10-2018 IPR013189 Glycosyl hydrolase family 32, C-terminal AFK25_07505 71f63dd0ee0ded5c4ff1cbf2fd989685 186 SUPERFAMILY SSF52833 6 185 2.07E-51 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_07505 71f63dd0ee0ded5c4ff1cbf2fd989685 186 Pfam PF00578 AhpC/TSA family 12 129 4.3E-19 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFK25_07505 71f63dd0ee0ded5c4ff1cbf2fd989685 186 Gene3D G3DSA:3.40.30.10 1 186 6.9E-58 T 11-10-2018 AFK25_05460 e2846dbd7ff7051ce9e4948610824eb6 212 SUPERFAMILY SSF63999 3 119 4.32E-32 T 11-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 AFK25_05460 e2846dbd7ff7051ce9e4948610824eb6 212 SMART SM00983 139 204 5.0E-22 T 11-10-2018 IPR007373 Thiamin pyrophosphokinase, thiamin-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 AFK25_05460 e2846dbd7ff7051ce9e4948610824eb6 212 Gene3D G3DSA:3.40.50.10240 1 212 3.5E-77 T 11-10-2018 IPR036759 Thiamin pyrophosphokinase, catalytic domain superfamily GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 AFK25_05460 e2846dbd7ff7051ce9e4948610824eb6 212 TIGRFAM TIGR01378 thi_PPkinase: thiamine pyrophosphokinase 5 206 7.9E-59 T 11-10-2018 IPR006282 Thiamin pyrophosphokinase GO:0004788|GO:0006772 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 AFK25_05460 e2846dbd7ff7051ce9e4948610824eb6 212 Pfam PF04263 Thiamin pyrophosphokinase, catalytic domain 25 125 8.5E-19 T 11-10-2018 IPR007371 Thiamin pyrophosphokinase, catalytic domain GO:0004788|GO:0005524|GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 AFK25_05460 e2846dbd7ff7051ce9e4948610824eb6 212 Pfam PF04265 Thiamin pyrophosphokinase, vitamin B1 binding domain 141 203 6.7E-15 T 11-10-2018 IPR007373 Thiamin pyrophosphokinase, thiamin-binding domain GO:0009229|GO:0030975 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 AFK25_05460 e2846dbd7ff7051ce9e4948610824eb6 212 SUPERFAMILY SSF63862 130 209 4.18E-13 T 11-10-2018 IPR036371 Thiamin pyrophosphokinase, thiamin-binding domain superfamily GO:0009229 KEGG: 00730+2.7.6.2|MetaCyc: PWY-6898|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|Reactome: R-HSA-196819 AFK25_04300 cc2a218728fce8ddf60cdd2f2a9ea084 296 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 291 1.0E-21 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_04300 cc2a218728fce8ddf60cdd2f2a9ea084 296 Gene3D G3DSA:1.10.3720.10 52 295 2.2E-71 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_04300 cc2a218728fce8ddf60cdd2f2a9ea084 296 SUPERFAMILY SSF161098 56 285 8.11E-61 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_03155 a2754b84ddc87411c40a6255ae6c3295 221 Pfam PF01553 Acyltransferase 37 153 6.2E-19 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFK25_03155 a2754b84ddc87411c40a6255ae6c3295 221 SUPERFAMILY SSF69593 11 199 1.7E-24 T 11-10-2018 AFK25_03155 a2754b84ddc87411c40a6255ae6c3295 221 SMART SM00563 40 156 1.3E-20 T 11-10-2018 IPR002123 Phospholipid/glycerol acyltransferase GO:0016746 AFK25_07585 b9a577e2c5060e6e7636686815968847 436 Pfam PF13726 Na+-H+ antiporter family 2 88 1.1E-33 T 11-10-2018 IPR032813 Putative Na+/H+ antiporter, N-terminal AFK25_07585 b9a577e2c5060e6e7636686815968847 436 Pfam PF03553 Na+/H+ antiporter family 151 430 2.2E-69 T 11-10-2018 IPR018461 Na+/H+ antiporter, NhaC-like, C-terminal GO:0016021 AFK25_10885 09ac51dd1491678256e7aa5a08fe1b65 510 SUPERFAMILY SSF51905 2 381 3.6E-62 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_10885 09ac51dd1491678256e7aa5a08fe1b65 510 Pfam PF02910 Fumarate reductase flavoprotein C-term 407 497 9.7E-10 T 11-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFK25_10885 09ac51dd1491678256e7aa5a08fe1b65 510 Gene3D G3DSA:3.90.700.10 223 320 7.3E-138 T 11-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFK25_10885 09ac51dd1491678256e7aa5a08fe1b65 510 TIGRFAM TIGR00551 nadB: L-aspartate oxidase 3 485 5.8E-163 T 11-10-2018 IPR005288 L-aspartate oxidase GO:0005737|GO:0008734|GO:0009435|GO:0055114 KEGG: 00250+1.4.3.16|KEGG: 00760+1.4.3.16|MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFK25_10885 09ac51dd1491678256e7aa5a08fe1b65 510 Gene3D G3DSA:1.20.58.100 379 485 5.3E-16 T 11-10-2018 AFK25_10885 09ac51dd1491678256e7aa5a08fe1b65 510 SUPERFAMILY SSF46977 406 502 5.63E-18 T 11-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFK25_10885 09ac51dd1491678256e7aa5a08fe1b65 510 SUPERFAMILY SSF56425 215 325 3.29E-34 T 11-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFK25_10885 09ac51dd1491678256e7aa5a08fe1b65 510 Gene3D G3DSA:3.50.50.60 8 371 7.3E-138 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_10885 09ac51dd1491678256e7aa5a08fe1b65 510 Pfam PF00890 FAD binding domain 5 365 3.2E-86 T 11-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFK25_10885 09ac51dd1491678256e7aa5a08fe1b65 510 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 8.0E-6 T 11-10-2018 AFK25_10885 09ac51dd1491678256e7aa5a08fe1b65 510 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 328 350 8.0E-6 T 11-10-2018 AFK25_10590 a50c4013dba892b8d1d90a29a1563c46 60 Gene3D G3DSA:3.30.70.1890 2 58 3.9E-5 T 11-10-2018 AFK25_00800 f3534479d767ad9452a36315e656aa37 198 PIRSF PIRSF029886 1 198 1.6E-83 T 11-10-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 AFK25_00800 f3534479d767ad9452a36315e656aa37 198 Pfam PF14089 KinB-signalling pathway activation in sporulation 17 195 6.8E-84 T 11-10-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 AFK25_00800 f3534479d767ad9452a36315e656aa37 198 SMART SM01251 17 196 2.5E-126 T 11-10-2018 IPR024164 KinB-signalling pathway activation protein GO:0045881 AFK25_12260 7c1deeceeb9b28fad638b3850750378c 475 Pfam PF00501 AMP-binding enzyme 8 380 8.1E-92 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFK25_12260 7c1deeceeb9b28fad638b3850750378c 475 Gene3D G3DSA:3.40.50.12780 1 377 1.4E-123 T 11-10-2018 AFK25_12260 7c1deeceeb9b28fad638b3850750378c 475 SUPERFAMILY SSF56801 2 474 1.07E-146 T 11-10-2018 AFK25_12260 7c1deeceeb9b28fad638b3850750378c 475 Pfam PF13193 AMP-binding enzyme C-terminal domain 389 463 3.6E-23 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFK25_12260 7c1deeceeb9b28fad638b3850750378c 475 PRINTS PR00154 AMP-binding signature 147 155 6.4E-5 T 11-10-2018 IPR020459 AMP-binding AFK25_12260 7c1deeceeb9b28fad638b3850750378c 475 PRINTS PR00154 AMP-binding signature 135 146 6.4E-5 T 11-10-2018 IPR020459 AMP-binding AFK25_12260 7c1deeceeb9b28fad638b3850750378c 475 Hamap MF_00731 2-succinylbenzoate--CoA ligase [menE]. 2 472 47.207 T 11-10-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 AFK25_12260 7c1deeceeb9b28fad638b3850750378c 475 ProSitePatterns PS00455 Putative AMP-binding domain signature. 140 151 - T 11-10-2018 IPR020845 AMP-binding, conserved site AFK25_12260 7c1deeceeb9b28fad638b3850750378c 475 Gene3D G3DSA:3.30.300.310 378 475 5.4E-36 T 11-10-2018 AFK25_12260 7c1deeceeb9b28fad638b3850750378c 475 TIGRFAM TIGR01923 menE: O-succinylbenzoate-CoA ligase 27 469 1.6E-151 T 11-10-2018 IPR010192 2-succinylbenzoate--CoA ligase GO:0005524|GO:0008756|GO:0009234 KEGG: 00130+6.2.1.26|MetaCyc: PWY-5837 AFK25_05005 21d1d137a0b65b8b5ba958523d2e313c 442 Pfam PF13276 HTH-like domain 195 250 4.4E-12 T 11-10-2018 IPR025948 HTH-like domain AFK25_05005 21d1d137a0b65b8b5ba958523d2e313c 442 Gene3D G3DSA:3.30.420.10 274 439 1.5E-8 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFK25_05005 21d1d137a0b65b8b5ba958523d2e313c 442 SUPERFAMILY SSF53098 272 437 1.67E-28 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_05005 21d1d137a0b65b8b5ba958523d2e313c 442 Pfam PF00665 Integrase core domain 280 395 6.4E-22 T 11-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFK25_12840 7625bcacf85cd34e8ca42f41a69815e3 167 Gene3D G3DSA:2.30.110.10 3 165 1.5E-48 T 11-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFK25_12840 7625bcacf85cd34e8ca42f41a69815e3 167 SUPERFAMILY SSF50475 5 146 4.86E-27 T 11-10-2018 AFK25_12840 7625bcacf85cd34e8ca42f41a69815e3 167 PIRSF PIRSF004633 1 166 3.7E-45 T 11-10-2018 IPR014419 Heme utilization protein with pyridoxamine 5'-phosphate domain AFK25_12840 7625bcacf85cd34e8ca42f41a69815e3 167 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 7 87 2.6E-13 T 11-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFK25_09135 a5f93141e7deec0bc2b1d885aa88f700 82 SUPERFAMILY SSF54862 3 73 1.42E-13 T 11-10-2018 AFK25_09135 a5f93141e7deec0bc2b1d885aa88f700 82 PRINTS PR00352 3Fe-4S ferredoxin signature 55 67 6.1E-8 T 11-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFK25_09135 a5f93141e7deec0bc2b1d885aa88f700 82 PRINTS PR00352 3Fe-4S ferredoxin signature 7 18 6.1E-8 T 11-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFK25_09135 a5f93141e7deec0bc2b1d885aa88f700 82 PRINTS PR00352 3Fe-4S ferredoxin signature 18 28 6.1E-8 T 11-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AFK25_09135 a5f93141e7deec0bc2b1d885aa88f700 82 Gene3D G3DSA:3.30.70.20 2 82 1.0E-36 T 11-10-2018 AFK25_09135 a5f93141e7deec0bc2b1d885aa88f700 82 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 7 69 2.1E-21 T 11-10-2018 AFK25_04560 eacd2b5bc32946782e7c076f9286b932 418 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 308 412 9.0E-21 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_04560 eacd2b5bc32946782e7c076f9286b932 418 SMART SM00388 204 267 4.4E-16 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_04560 eacd2b5bc32946782e7c076f9286b932 418 Pfam PF00512 His Kinase A (phospho-acceptor) domain 206 264 5.1E-17 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_04560 eacd2b5bc32946782e7c076f9286b932 418 SUPERFAMILY SSF55785 59 187 4.36E-16 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_04560 eacd2b5bc32946782e7c076f9286b932 418 Pfam PF08448 PAS fold 77 190 2.6E-12 T 11-10-2018 IPR013656 PAS fold-4 AFK25_04560 eacd2b5bc32946782e7c076f9286b932 418 SMART SM00387 308 414 4.5E-28 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_04560 eacd2b5bc32946782e7c076f9286b932 418 Gene3D G3DSA:3.30.450.20 55 201 2.5E-18 T 11-10-2018 AFK25_04560 eacd2b5bc32946782e7c076f9286b932 418 SUPERFAMILY SSF55874 269 412 1.31E-38 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_04560 eacd2b5bc32946782e7c076f9286b932 418 Gene3D G3DSA:1.10.287.130 207 259 1.1E-18 T 11-10-2018 AFK25_04560 eacd2b5bc32946782e7c076f9286b932 418 SUPERFAMILY SSF47384 199 265 8.83E-15 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFK25_04560 eacd2b5bc32946782e7c076f9286b932 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 398 411 6.7E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04560 eacd2b5bc32946782e7c076f9286b932 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 345 359 6.7E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04560 eacd2b5bc32946782e7c076f9286b932 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 374 392 6.7E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04560 eacd2b5bc32946782e7c076f9286b932 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 363 373 6.7E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04560 eacd2b5bc32946782e7c076f9286b932 418 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 67 195 1.7E-11 T 11-10-2018 IPR000014 PAS domain AFK25_04560 eacd2b5bc32946782e7c076f9286b932 418 Gene3D G3DSA:3.30.565.10 260 412 8.2E-41 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_13755 3c7f344270ff5d8032fff298baed3721 335 TIGRFAM TIGR02870 spore_II_D: stage II sporulation protein D 11 327 1.4E-126 T 11-10-2018 IPR014225 Sporulation stage II, protein D firmicutes AFK25_13755 3c7f344270ff5d8032fff298baed3721 335 Pfam PF08486 Stage II sporulation protein 62 167 4.5E-26 T 11-10-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal AFK25_13755 3c7f344270ff5d8032fff298baed3721 335 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 67 326 2.0E-76 T 11-10-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 AFK25_06040 1a5e53987407fc69a8a5acebd817357b 138 PRINTS PR01438 Universal stress protein signature 98 110 1.2E-17 T 11-10-2018 IPR006015 Universal stress protein A AFK25_06040 1a5e53987407fc69a8a5acebd817357b 138 PRINTS PR01438 Universal stress protein signature 116 138 1.2E-17 T 11-10-2018 IPR006015 Universal stress protein A AFK25_06040 1a5e53987407fc69a8a5acebd817357b 138 PRINTS PR01438 Universal stress protein signature 1 19 1.2E-17 T 11-10-2018 IPR006015 Universal stress protein A AFK25_06040 1a5e53987407fc69a8a5acebd817357b 138 SUPERFAMILY SSF52402 1 138 1.26E-32 T 11-10-2018 AFK25_06040 1a5e53987407fc69a8a5acebd817357b 138 Pfam PF00582 Universal stress protein family 1 138 3.2E-30 T 11-10-2018 IPR006016 UspA AFK25_06040 1a5e53987407fc69a8a5acebd817357b 138 Gene3D G3DSA:3.40.50.620 1 138 5.1E-33 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_00955 ee23e8dbbcb19e142333bf145e7bf852 335 PIRSF PIRSF037431 1 335 8.8E-125 T 11-10-2018 IPR017202 Sensor histidine kinase LiaS/VraS GO:0000155|GO:0000160|GO:0004673|GO:0016021 AFK25_00955 ee23e8dbbcb19e142333bf145e7bf852 335 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 243 334 3.0E-6 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_00955 ee23e8dbbcb19e142333bf145e7bf852 335 SMART SM00387 243 335 9.4E-6 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_00955 ee23e8dbbcb19e142333bf145e7bf852 335 SUPERFAMILY SSF55874 212 334 9.43E-20 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_00955 ee23e8dbbcb19e142333bf145e7bf852 335 Pfam PF07730 Histidine kinase 141 207 6.4E-17 T 11-10-2018 IPR011712 Signal transduction histidine kinase, subgroup 3, dimerisation and phosphoacceptor domain GO:0000155|GO:0000160|GO:0016021|GO:0046983 AFK25_00955 ee23e8dbbcb19e142333bf145e7bf852 335 Gene3D G3DSA:3.30.565.10 205 335 1.0E-31 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_02125 5255dc82e291c3cc25b5b1e7a0ca5f33 136 Pfam PF13673 Acetyltransferase (GNAT) domain 46 121 2.0E-7 T 11-10-2018 IPR000182 GNAT domain AFK25_02125 5255dc82e291c3cc25b5b1e7a0ca5f33 136 Gene3D G3DSA:3.40.630.30 1 125 1.1E-31 T 11-10-2018 AFK25_02125 5255dc82e291c3cc25b5b1e7a0ca5f33 136 SUPERFAMILY SSF55729 10 121 4.58E-17 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFK25_09665 ef9c244f412f9e5cad35c53ff4ebe495 273 SUPERFAMILY SSF51735 1 158 5.65E-31 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_09665 ef9c244f412f9e5cad35c53ff4ebe495 273 ProSitePatterns PS00521 Delta 1-pyrroline-5-carboxylate reductase signature. 220 242 - T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AFK25_09665 ef9c244f412f9e5cad35c53ff4ebe495 273 PIRSF PIRSF000193 1 267 3.7E-77 T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AFK25_09665 ef9c244f412f9e5cad35c53ff4ebe495 273 Hamap MF_01925 Pyrroline-5-carboxylate reductase [proC]. 1 264 26.942 T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AFK25_09665 ef9c244f412f9e5cad35c53ff4ebe495 273 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 97 2.0E-21 T 11-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal AFK25_09665 ef9c244f412f9e5cad35c53ff4ebe495 273 TIGRFAM TIGR00112 proC: pyrroline-5-carboxylate reductase 3 264 4.0E-85 T 11-10-2018 IPR000304 Pyrroline-5-carboxylate reductase GO:0004735|GO:0006561|GO:0055114 KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AFK25_09665 ef9c244f412f9e5cad35c53ff4ebe495 273 Gene3D G3DSA:3.40.50.720 1 161 3.5E-47 T 11-10-2018 AFK25_09665 ef9c244f412f9e5cad35c53ff4ebe495 273 SUPERFAMILY SSF48179 159 266 1.0E-34 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFK25_09665 ef9c244f412f9e5cad35c53ff4ebe495 273 Gene3D G3DSA:1.10.3730.10 162 268 2.3E-40 T 11-10-2018 AFK25_09665 ef9c244f412f9e5cad35c53ff4ebe495 273 Pfam PF14748 Pyrroline-5-carboxylate reductase dimerisation 160 264 3.5E-36 T 11-10-2018 IPR029036 Pyrroline-5-carboxylate reductase, dimerisation domain KEGG: 00330+1.5.1.2|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|Reactome: R-HSA-70614 AFK25_12105 4d811d2ddf80a67f43701631a08f9d28 482 Pfam PF03050 Transposase IS66 family 177 443 4.2E-61 T 11-10-2018 IPR004291 Transposase, IS66 AFK25_12105 4d811d2ddf80a67f43701631a08f9d28 482 Pfam PF13005 zinc-finger binding domain of transposase IS66 117 161 4.6E-12 T 11-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 AFK25_06715 4cb05fb030028d727bb3e97d090af4f8 285 Gene3D G3DSA:1.10.260.40 1 103 2.0E-30 T 11-10-2018 AFK25_06715 4cb05fb030028d727bb3e97d090af4f8 285 Pfam PF13464 Domain of unknown function (DUF4115) 206 266 9.9E-8 T 11-10-2018 IPR025194 Domain of unknown function DUF4115 AFK25_06715 4cb05fb030028d727bb3e97d090af4f8 285 Pfam PF13413 Helix-turn-helix domain 7 68 2.4E-21 T 11-10-2018 AFK25_06715 4cb05fb030028d727bb3e97d090af4f8 285 SUPERFAMILY SSF47413 2 75 1.41E-9 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFK25_06715 4cb05fb030028d727bb3e97d090af4f8 285 SMART SM00530 7 68 2.1E-4 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFK25_13095 62bbfcc94ccaba6c2d294fe5d2c48d6d 297 PIRSF PIRSF003097 1 297 2.2E-88 T 11-10-2018 IPR004513 Cell division protein FtsX GO:0016021 AFK25_13095 62bbfcc94ccaba6c2d294fe5d2c48d6d 297 Pfam PF02687 FtsX-like permease family 200 293 1.6E-7 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFK25_13095 62bbfcc94ccaba6c2d294fe5d2c48d6d 297 Gene3D G3DSA:3.30.70.3040 52 156 1.5E-10 T 11-10-2018 AFK25_04235 312315234a9b5bb5367b1959e76dc8fd 418 Gene3D G3DSA:1.10.287.130 208 267 1.5E-57 T 11-10-2018 AFK25_04235 312315234a9b5bb5367b1959e76dc8fd 418 Pfam PF07694 5TMR of 5TMR-LYT 32 182 1.9E-14 T 11-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 AFK25_04235 312315234a9b5bb5367b1959e76dc8fd 418 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 313 414 5.8E-18 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_04235 312315234a9b5bb5367b1959e76dc8fd 418 SMART SM00387 310 416 2.1E-21 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_04235 312315234a9b5bb5367b1959e76dc8fd 418 SUPERFAMILY SSF55874 259 414 2.36E-31 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_04235 312315234a9b5bb5367b1959e76dc8fd 418 Gene3D G3DSA:3.30.565.10 268 413 1.5E-57 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_04235 312315234a9b5bb5367b1959e76dc8fd 418 SUPERFAMILY SSF47384 200 266 4.12E-15 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFK25_04235 312315234a9b5bb5367b1959e76dc8fd 418 SMART SM00388 204 270 2.3E-12 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_04235 312315234a9b5bb5367b1959e76dc8fd 418 Pfam PF00512 His Kinase A (phospho-acceptor) domain 206 266 9.4E-14 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_04235 312315234a9b5bb5367b1959e76dc8fd 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 365 375 1.0E-11 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04235 312315234a9b5bb5367b1959e76dc8fd 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 347 361 1.0E-11 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04235 312315234a9b5bb5367b1959e76dc8fd 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 400 413 1.0E-11 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04235 312315234a9b5bb5367b1959e76dc8fd 418 PRINTS PR00344 Bacterial sensor protein C-terminal signature 376 394 1.0E-11 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_13935 4c9163d0fce7f4748637e95ea7b85ca9 358 Hamap MF_00093 Peptide chain release factor 1 [prfA]. 1 355 40.961 T 11-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 AFK25_13935 4c9163d0fce7f4748637e95ea7b85ca9 358 SUPERFAMILY SSF75620 8 351 1.96E-137 T 11-10-2018 AFK25_13935 4c9163d0fce7f4748637e95ea7b85ca9 358 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 226 242 - T 11-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 AFK25_13935 4c9163d0fce7f4748637e95ea7b85ca9 358 Gene3D G3DSA:1.20.58.410 1 101 1.3E-8 T 11-10-2018 AFK25_13935 4c9163d0fce7f4748637e95ea7b85ca9 358 SMART SM00937 63 177 1.4E-68 T 11-10-2018 IPR005139 Peptide chain release factor GO:0006415 AFK25_13935 4c9163d0fce7f4748637e95ea7b85ca9 358 Gene3D G3DSA:3.30.70.1660 110 340 2.3E-98 T 11-10-2018 AFK25_13935 4c9163d0fce7f4748637e95ea7b85ca9 358 Pfam PF03462 PCRF domain 9 202 2.0E-75 T 11-10-2018 IPR005139 Peptide chain release factor GO:0006415 AFK25_13935 4c9163d0fce7f4748637e95ea7b85ca9 358 TIGRFAM TIGR00019 prfA: peptide chain release factor 1 2 355 1.5E-172 T 11-10-2018 IPR004373 Peptide chain release factor 1 GO:0005737|GO:0006415|GO:0016149 AFK25_13935 4c9163d0fce7f4748637e95ea7b85ca9 358 Pfam PF00472 RF-1 domain 210 319 4.7E-42 T 11-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 AFK25_13935 4c9163d0fce7f4748637e95ea7b85ca9 358 Gene3D G3DSA:3.30.160.20 209 295 2.3E-98 T 11-10-2018 AFK25_03380 dce9b057f49ddb56c582b4bdc6c048f6 385 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 1 378 68.571 T 11-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 AFK25_03380 dce9b057f49ddb56c582b4bdc6c048f6 385 Pfam PF00202 Aminotransferase class-III 7 375 1.4E-124 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFK25_03380 dce9b057f49ddb56c582b4bdc6c048f6 385 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 202 239 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFK25_03380 dce9b057f49ddb56c582b4bdc6c048f6 385 Gene3D G3DSA:3.40.640.10 45 284 1.5E-138 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_03380 dce9b057f49ddb56c582b4bdc6c048f6 385 Gene3D G3DSA:3.90.1150.10 10 365 1.5E-138 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_03380 dce9b057f49ddb56c582b4bdc6c048f6 385 SUPERFAMILY SSF53383 3 376 1.65E-128 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_03380 dce9b057f49ddb56c582b4bdc6c048f6 385 PIRSF PIRSF000521 4 112 1.3E-6 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFK25_03380 dce9b057f49ddb56c582b4bdc6c048f6 385 PIRSF PIRSF000521 104 149 0.0048 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFK25_03380 dce9b057f49ddb56c582b4bdc6c048f6 385 PIRSF PIRSF000521 150 378 5.6E-41 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFK25_03380 dce9b057f49ddb56c582b4bdc6c048f6 385 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 2 375 1.9E-153 T 11-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 AFK25_04550 adc9925fedd5866be62cd09f7de3e0f7 174 Pfam PF08281 Sigma-70, region 4 98 147 3.9E-9 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFK25_04550 adc9925fedd5866be62cd09f7de3e0f7 174 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 2 150 2.7E-22 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFK25_04550 adc9925fedd5866be62cd09f7de3e0f7 174 SUPERFAMILY SSF88946 3 72 7.46E-14 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_04550 adc9925fedd5866be62cd09f7de3e0f7 174 Gene3D G3DSA:1.10.1740.10 1 70 1.9E-8 T 11-10-2018 AFK25_04550 adc9925fedd5866be62cd09f7de3e0f7 174 Gene3D G3DSA:1.10.10.10 81 153 1.7E-10 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_04550 adc9925fedd5866be62cd09f7de3e0f7 174 SUPERFAMILY SSF88659 94 152 1.27E-13 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFK25_04550 adc9925fedd5866be62cd09f7de3e0f7 174 Pfam PF04542 Sigma-70 region 2 7 73 7.8E-13 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_12165 cb6f222c3288c524e639b4ffa3d9b864 268 Gene3D G3DSA:1.10.3720.10 70 267 1.6E-21 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_12165 cb6f222c3288c524e639b4ffa3d9b864 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 91 264 6.2E-22 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_12165 cb6f222c3288c524e639b4ffa3d9b864 268 SUPERFAMILY SSF161098 71 252 1.26E-28 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_04200 9a241aab318b6bd78c3db4b5f159a6f0 365 Pfam PF07755 Domain of unknown function (DUF1611_C) P-loop domain 150 347 7.6E-66 T 11-10-2018 IPR035086 Domain of unknown function DUF1611, P-loop AFK25_04200 9a241aab318b6bd78c3db4b5f159a6f0 365 Gene3D G3DSA:3.40.50.300 145 353 1.2E-72 T 11-10-2018 AFK25_04200 9a241aab318b6bd78c3db4b5f159a6f0 365 Pfam PF17396 Domain of unknown function (DUF1611_N) Rossmann-like domain 45 142 2.1E-23 T 11-10-2018 IPR035402 Domain of unknown function DUF1611-N, Rossmann-like domain AFK25_04200 9a241aab318b6bd78c3db4b5f159a6f0 365 Gene3D G3DSA:3.40.50.720 2 144 1.2E-46 T 11-10-2018 AFK25_04200 9a241aab318b6bd78c3db4b5f159a6f0 365 PIRSF PIRSF026760 6 357 8.1E-121 T 11-10-2018 IPR011669 Uncharacterised conserved protein UCP026760 AFK25_04200 9a241aab318b6bd78c3db4b5f159a6f0 365 SUPERFAMILY SSF52540 6 354 1.37E-102 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_06535 10872fccdb3b0eb00ed38e5c1515e9cf 396 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 85 132 7.0E-10 T 11-10-2018 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain AFK25_06535 10872fccdb3b0eb00ed38e5c1515e9cf 396 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 34 78 3.6E-13 T 11-10-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger AFK25_06535 10872fccdb3b0eb00ed38e5c1515e9cf 396 Pfam PF01610 Transposase 155 382 6.1E-66 T 11-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain AFK25_08205 10872fccdb3b0eb00ed38e5c1515e9cf 396 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 85 132 7.0E-10 T 11-10-2018 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain AFK25_08205 10872fccdb3b0eb00ed38e5c1515e9cf 396 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 34 78 3.6E-13 T 11-10-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger AFK25_08205 10872fccdb3b0eb00ed38e5c1515e9cf 396 Pfam PF01610 Transposase 155 382 6.1E-66 T 11-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain AFK25_11600 875a700dd2460ced45e01b6f72353f79 156 Gene3D G3DSA:3.10.129.10 9 145 1.9E-26 T 11-10-2018 AFK25_11600 875a700dd2460ced45e01b6f72353f79 156 SUPERFAMILY SSF54637 10 145 1.68E-22 T 11-10-2018 IPR029069 HotDog domain superfamily AFK25_11600 875a700dd2460ced45e01b6f72353f79 156 Pfam PF01575 MaoC like domain 28 125 8.3E-8 T 11-10-2018 IPR002539 MaoC-like dehydratase domain AFK25_13615 3aad283d955772c9792a462d48d8bb54 327 SUPERFAMILY SSF55347 127 290 1.8E-29 T 11-10-2018 AFK25_13615 3aad283d955772c9792a462d48d8bb54 327 Gene3D G3DSA:3.40.50.720 1 133 1.2E-37 T 11-10-2018 AFK25_13615 3aad283d955772c9792a462d48d8bb54 327 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 2 119 1.3E-26 T 11-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFK25_13615 3aad283d955772c9792a462d48d8bb54 327 Gene3D G3DSA:3.30.360.10 134 327 4.4E-64 T 11-10-2018 AFK25_13615 3aad283d955772c9792a462d48d8bb54 327 SUPERFAMILY SSF51735 2 152 3.31E-46 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_01075 4870befc617bfe789f580e3dc0eaf804 458 Hamap MF_02019 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [murF]. 4 457 35.058 T 11-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFK25_01075 4870befc617bfe789f580e3dc0eaf804 458 Pfam PF01225 Mur ligase family, catalytic domain 27 101 2.2E-10 T 11-10-2018 IPR000713 Mur ligase, N-terminal catalytic domain GO:0005524|GO:0009058 AFK25_01075 4870befc617bfe789f580e3dc0eaf804 458 Pfam PF08245 Mur ligase middle domain 111 297 2.7E-51 T 11-10-2018 IPR013221 Mur ligase, central GO:0005524|GO:0009058 AFK25_01075 4870befc617bfe789f580e3dc0eaf804 458 Gene3D G3DSA:3.40.1190.10 87 314 5.3E-72 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFK25_01075 4870befc617bfe789f580e3dc0eaf804 458 Gene3D G3DSA:3.90.190.20 316 458 4.2E-47 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFK25_01075 4870befc617bfe789f580e3dc0eaf804 458 SUPERFAMILY SSF63418 20 102 3.14E-24 T 11-10-2018 IPR035911 MurE/MurF, N-terminal AFK25_01075 4870befc617bfe789f580e3dc0eaf804 458 SUPERFAMILY SSF53623 107 313 2.09E-56 T 11-10-2018 IPR036565 Mur-like, catalytic domain superfamily GO:0005524|GO:0009058 Reactome: R-HSA-196757 AFK25_01075 4870befc617bfe789f580e3dc0eaf804 458 Gene3D G3DSA:3.40.1390.10 3 86 6.3E-20 T 11-10-2018 AFK25_01075 4870befc617bfe789f580e3dc0eaf804 458 Pfam PF02875 Mur ligase family, glutamate ligase domain 317 399 2.1E-20 T 11-10-2018 IPR004101 Mur ligase, C-terminal GO:0005524|GO:0009058|GO:0016874 AFK25_01075 4870befc617bfe789f580e3dc0eaf804 458 TIGRFAM TIGR01143 murF: UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase 32 456 2.4E-141 T 11-10-2018 IPR005863 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase GO:0005524|GO:0005737|GO:0047480|GO:0071555 KEGG: 00300+6.3.2.10|KEGG: 00550+6.3.2.10|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFK25_01075 4870befc617bfe789f580e3dc0eaf804 458 SUPERFAMILY SSF53244 317 456 6.04E-39 T 11-10-2018 IPR036615 Mur ligase, C-terminal domain superfamily GO:0005524|GO:0009058|GO:0016874 Reactome: R-HSA-196757 AFK25_11130 b4b6fe8588fffc93975edb785cd3b104 193 TIGRFAM TIGR03598 GTPase_YsxC: ribosome biogenesis GTP-binding protein YsxC 7 189 1.4E-69 T 11-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 AFK25_11130 b4b6fe8588fffc93975edb785cd3b104 193 Gene3D G3DSA:3.40.50.300 1 193 7.5E-55 T 11-10-2018 AFK25_11130 b4b6fe8588fffc93975edb785cd3b104 193 SUPERFAMILY SSF52540 17 193 7.83E-39 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_11130 b4b6fe8588fffc93975edb785cd3b104 193 Pfam PF01926 50S ribosome-binding GTPase 26 143 6.6E-21 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_11130 b4b6fe8588fffc93975edb785cd3b104 193 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 11 193 28.449 T 11-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 AFK25_05210 11f35c042c233f6e3f157fc77be59ad6 324 ProSitePatterns PS01348 MraY family signature 2. 168 179 - T 11-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_05210 11f35c042c233f6e3f157fc77be59ad6 324 Hamap MF_00038 Phospho-N-acetylmuramoyl-pentapeptide-transferase [mraY]. 5 322 24.696 T 11-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_05210 11f35c042c233f6e3f157fc77be59ad6 324 ProSitePatterns PS01347 MraY family signature 1. 48 60 - T 11-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_05210 11f35c042c233f6e3f157fc77be59ad6 324 TIGRFAM TIGR00445 mraY: phospho-N-acetylmuramoyl-pentapeptide-transferase 17 324 2.0E-121 T 11-10-2018 IPR003524 Phospho-N-acetylmuramoyl-pentapeptide transferase GO:0008963|GO:0016020 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_05210 11f35c042c233f6e3f157fc77be59ad6 324 Pfam PF00953 Glycosyl transferase family 4 83 248 1.3E-37 T 11-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 AFK25_05210 11f35c042c233f6e3f157fc77be59ad6 324 Pfam PF10555 Phospho-N-acetylmuramoyl-pentapeptide-transferase signature 1 48 60 1.6E-5 T 11-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_02000 a0e0c4455a84c21063d73b18aac97830 120 Pfam PF11023 Zinc-ribbon containing domain 4 114 2.1E-61 T 11-10-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 AFK25_02000 a0e0c4455a84c21063d73b18aac97830 120 Hamap MF_01502 UPF0295 protein . 2 116 36.98 T 11-10-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 AFK25_02000 a0e0c4455a84c21063d73b18aac97830 120 ProDom PD355753 MEMBRANE TRANSMEMBRANE UPF0295 BLI00901/BL05075 BT9727_0449 GK0479 BCE0593 YGZB PRECURSOR BA0538/GBAA0538/BAS0506 4 114 6.0E-49 T 11-10-2018 IPR020912 Uncharacterised protein family UPF0295 GO:0005887 AFK25_10255 4710c0aff9ebe3701be3684da464c9a7 315 Gene3D G3DSA:3.40.1010.20 104 197 1.3E-95 T 11-10-2018 AFK25_10255 4710c0aff9ebe3701be3684da464c9a7 315 TIGRFAM TIGR00216 ispH_lytB: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 3 286 9.4E-91 T 11-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 AFK25_10255 4710c0aff9ebe3701be3684da464c9a7 315 Gene3D G3DSA:3.40.1010.20 7 284 1.3E-95 T 11-10-2018 AFK25_10255 4710c0aff9ebe3701be3684da464c9a7 315 Hamap MF_00191 4-hydroxy-3-methylbut-2-enyl diphosphate reductase [ispH]. 1 288 32.103 T 11-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 AFK25_10255 4710c0aff9ebe3701be3684da464c9a7 315 Gene3D G3DSA:3.40.50.11270 12 103 1.3E-95 T 11-10-2018 AFK25_10255 4710c0aff9ebe3701be3684da464c9a7 315 Pfam PF02401 LytB protein 4 284 2.1E-81 T 11-10-2018 IPR003451 4-hydroxy-3-methylbut-2-enyl diphosphate reductase GO:0019288|GO:0046872|GO:0050992|GO:0051745 KEGG: 00900+1.17.7.4|MetaCyc: PWY-7560 AFK25_12275 9de2df45dfbe368ddc47071fb37cab37 577 SUPERFAMILY SSF52518 380 566 1.1E-30 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold AFK25_12275 9de2df45dfbe368ddc47071fb37cab37 577 SUPERFAMILY SSF52518 7 180 1.21E-39 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold AFK25_12275 9de2df45dfbe368ddc47071fb37cab37 577 SUPERFAMILY SSF52467 164 365 3.04E-13 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFK25_12275 9de2df45dfbe368ddc47071fb37cab37 577 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 9 177 1.9E-41 T 11-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AFK25_12275 9de2df45dfbe368ddc47071fb37cab37 577 Gene3D G3DSA:3.40.50.970 1 171 1.7E-73 T 11-10-2018 AFK25_12275 9de2df45dfbe368ddc47071fb37cab37 577 PIRSF PIRSF004983 1 571 4.4E-205 T 11-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 AFK25_12275 9de2df45dfbe368ddc47071fb37cab37 577 Pfam PF16582 Middle domain of thiamine pyrophosphate 211 398 2.7E-19 T 11-10-2018 IPR032264 Menaquinone biosynthesis protein MenD, middle domain KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 AFK25_12275 9de2df45dfbe368ddc47071fb37cab37 577 TIGRFAM TIGR00173 menD: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase 7 440 1.9E-160 T 11-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 AFK25_12275 9de2df45dfbe368ddc47071fb37cab37 577 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 431 547 1.8E-8 T 11-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFK25_12275 9de2df45dfbe368ddc47071fb37cab37 577 Gene3D G3DSA:3.40.50.970 375 574 1.2E-67 T 11-10-2018 AFK25_12275 9de2df45dfbe368ddc47071fb37cab37 577 Hamap MF_01659 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [menD]. 1 565 37.487 T 11-10-2018 IPR004433 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase GO:0009234|GO:0030976|GO:0070204 KEGG: 00130+2.2.1.9|MetaCyc: PWY-5837 AFK25_12275 9de2df45dfbe368ddc47071fb37cab37 577 Gene3D G3DSA:3.40.50.1220 193 374 1.0E-59 T 11-10-2018 AFK25_11090 da86ab0b7e2723a7b1bf2ede501b4b71 301 Pfam PF01476 LysM domain 254 296 4.9E-10 T 11-10-2018 IPR018392 LysM domain AFK25_11090 da86ab0b7e2723a7b1bf2ede501b4b71 301 SUPERFAMILY SSF54106 252 297 9.02E-10 T 11-10-2018 AFK25_11090 da86ab0b7e2723a7b1bf2ede501b4b71 301 SMART SM00257 252 296 1.1E-9 T 11-10-2018 IPR018392 LysM domain AFK25_11090 da86ab0b7e2723a7b1bf2ede501b4b71 301 Gene3D G3DSA:3.10.350.10 242 301 3.2E-14 T 11-10-2018 IPR036779 LysM domain superfamily AFK25_02550 f98cbcdd4d6b9947c6de173e8fecc4f4 99 SUPERFAMILY SSF52821 2 95 9.56E-32 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_02550 f98cbcdd4d6b9947c6de173e8fecc4f4 99 SMART SM00450 4 99 6.8E-22 T 11-10-2018 IPR001763 Rhodanese-like domain AFK25_02550 f98cbcdd4d6b9947c6de173e8fecc4f4 99 Gene3D G3DSA:3.40.250.10 1 98 2.3E-30 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_02550 f98cbcdd4d6b9947c6de173e8fecc4f4 99 Pfam PF00581 Rhodanese-like domain 5 94 1.6E-16 T 11-10-2018 IPR001763 Rhodanese-like domain AFK25_00605 17a96030c0b11cdaed5d254a370e71c1 208 ProSitePatterns PS00474 Ribosomal protein L3 signature. 101 124 - T 11-10-2018 IPR019926 Ribosomal protein L3, conserved site AFK25_00605 17a96030c0b11cdaed5d254a370e71c1 208 Pfam PF00297 Ribosomal protein L3 86 179 2.2E-17 T 11-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00605 17a96030c0b11cdaed5d254a370e71c1 208 Gene3D G3DSA:2.40.50.620 32 95 2.6E-13 T 11-10-2018 AFK25_00605 17a96030c0b11cdaed5d254a370e71c1 208 SUPERFAMILY SSF50447 1 206 7.77E-83 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFK25_00605 17a96030c0b11cdaed5d254a370e71c1 208 Gene3D G3DSA:2.40.30.10 133 208 1.7E-18 T 11-10-2018 AFK25_00605 17a96030c0b11cdaed5d254a370e71c1 208 Hamap MF_01325_B 50S ribosomal protein L3 [rplC]. 1 205 39.685 T 11-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00605 17a96030c0b11cdaed5d254a370e71c1 208 TIGRFAM TIGR03625 L3_bact: 50S ribosomal protein uL3 3 202 1.1E-87 T 11-10-2018 IPR019927 Ribosomal protein L3, bacterial/organelle-type GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_02395 d4526b976e1b44d3ba412cb1ddc3831f 119 Pfam PF02924 Bacteriophage lambda head decoration protein D 21 108 1.0E-18 T 11-10-2018 IPR004195 Head decoration protein D AFK25_09460 f3c89be37e5de629476412fdf7874bc5 179 Gene3D G3DSA:3.90.79.10 5 179 1.3E-58 T 11-10-2018 AFK25_09460 f3c89be37e5de629476412fdf7874bc5 179 TIGRFAM TIGR00052 TIGR00052: nudix-type nucleoside diphosphatase, YffH/AdpP family 34 177 6.5E-25 T 11-10-2018 IPR004385 Nucleoside diphosphate pyrophosphatase GO:0016818|GO:0046872 Reactome: R-HSA-480985 AFK25_09460 f3c89be37e5de629476412fdf7874bc5 179 SUPERFAMILY SSF55811 7 178 6.63E-53 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFK25_09460 f3c89be37e5de629476412fdf7874bc5 179 ProDom PD037294 PEPTIDE ACMNPV ORF38 ORF ORF_59 ORF61 ORF7 PXORF52 ORF-30 ORF79 39 104 0.002 T 11-10-2018 AFK25_09460 f3c89be37e5de629476412fdf7874bc5 179 ProSitePatterns PS00893 Nudix box signature. 77 98 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFK25_09460 f3c89be37e5de629476412fdf7874bc5 179 Pfam PF00293 NUDIX domain 42 158 3.6E-19 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFK25_04745 2651dc907dcd87ffcce8a0527fe695ab 488 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 13 465 2.7E-162 T 11-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 AFK25_04745 2651dc907dcd87ffcce8a0527fe695ab 488 PIRSF PIRSF005690 2 480 1.4E-152 T 11-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 AFK25_01730 6663a73b30553e3f2779a6c1bc7720d9 195 Hamap MF_00065 Adenylyl-sulfate kinase [cysC]. 21 193 40.377 T 11-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFK25_01730 6663a73b30553e3f2779a6c1bc7720d9 195 Pfam PF01583 Adenylylsulphate kinase 23 176 8.7E-76 T 11-10-2018 AFK25_01730 6663a73b30553e3f2779a6c1bc7720d9 195 SUPERFAMILY SSF52540 21 191 1.5E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_01730 6663a73b30553e3f2779a6c1bc7720d9 195 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 5 189 2.3E-92 T 11-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AFK25_01730 6663a73b30553e3f2779a6c1bc7720d9 195 Gene3D G3DSA:3.40.50.300 1 195 4.1E-89 T 11-10-2018 AFK25_09940 2e23aa0626e9f2259bd443c094393eb5 292 Pfam PF01734 Patatin-like phospholipase 6 195 1.1E-29 T 11-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 AFK25_09940 2e23aa0626e9f2259bd443c094393eb5 292 SUPERFAMILY SSF52151 6 286 2.62E-42 T 11-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase AFK25_09940 2e23aa0626e9f2259bd443c094393eb5 292 Gene3D G3DSA:3.40.1090.10 103 290 5.0E-20 T 11-10-2018 AFK25_09940 2e23aa0626e9f2259bd443c094393eb5 292 Gene3D G3DSA:3.40.1090.20 2 100 4.5E-22 T 11-10-2018 AFK25_08295 906a084e8d8b90069be6143c38d95cf2 480 SUPERFAMILY SSF53720 2 474 3.93E-156 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFK25_08295 906a084e8d8b90069be6143c38d95cf2 480 Pfam PF00171 Aldehyde dehydrogenase family 12 472 1.8E-164 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFK25_08295 906a084e8d8b90069be6143c38d95cf2 480 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 247 254 - T 11-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 AFK25_08295 906a084e8d8b90069be6143c38d95cf2 480 Gene3D G3DSA:3.40.309.10 252 441 2.7E-163 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFK25_08295 906a084e8d8b90069be6143c38d95cf2 480 Gene3D G3DSA:3.40.605.10 8 468 2.7E-163 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFK25_01805 5ef4a965560b769b8043ba19a2e6274d 507 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 327 489 3.1E-53 T 11-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 AFK25_01805 5ef4a965560b769b8043ba19a2e6274d 507 Pfam PF05681 Fumarate hydratase (Fumerase) 6 281 2.2E-74 T 11-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 AFK25_01805 5ef4a965560b769b8043ba19a2e6274d 507 SUPERFAMILY SSF117457 318 489 4.45E-54 T 11-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 AFK25_01805 5ef4a965560b769b8043ba19a2e6274d 507 Pfam PF05683 Fumarase C-terminus 289 490 4.3E-65 T 11-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 AFK25_01805 5ef4a965560b769b8043ba19a2e6274d 507 Gene3D G3DSA:3.20.130.10 304 490 4.6E-67 T 11-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 AFK25_01805 5ef4a965560b769b8043ba19a2e6274d 507 PIRSF PIRSF001394 1 507 1.8E-201 T 11-10-2018 IPR011167 Iron-dependent fumarate hydratase GO:0004333|GO:0006091 KEGG: 00020+4.2.1.2|KEGG: 00620+4.2.1.2|KEGG: 00720+4.2.1.2|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7384 AFK25_01805 5ef4a965560b769b8043ba19a2e6274d 507 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 5 280 3.5E-64 T 11-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 AFK25_10135 db2641073d47c4321693f203fa2fb9f8 138 Gene3D G3DSA:1.10.8.1150 72 138 1.9E-10 T 11-10-2018 AFK25_10135 db2641073d47c4321693f203fa2fb9f8 138 Pfam PF02618 YceG-like family 77 137 3.0E-8 T 11-10-2018 IPR003770 Endolytic murein transglycosylase AFK25_11060 71be4d9e2c56f24c83fc7de60f40dd61 282 Gene3D G3DSA:1.25.40.20 198 282 1.1E-25 T 11-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily AFK25_11060 71be4d9e2c56f24c83fc7de60f40dd61 282 SMART SM00248 256 282 3700.0 T 11-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFK25_11060 71be4d9e2c56f24c83fc7de60f40dd61 282 SMART SM00248 55 84 0.58 T 11-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFK25_11060 71be4d9e2c56f24c83fc7de60f40dd61 282 SMART SM00248 190 219 1.4E-4 T 11-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFK25_11060 71be4d9e2c56f24c83fc7de60f40dd61 282 SMART SM00248 157 186 4.6E-5 T 11-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFK25_11060 71be4d9e2c56f24c83fc7de60f40dd61 282 SMART SM00248 124 153 0.0025 T 11-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFK25_11060 71be4d9e2c56f24c83fc7de60f40dd61 282 SMART SM00248 223 252 7.7E-5 T 11-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFK25_11060 71be4d9e2c56f24c83fc7de60f40dd61 282 PRINTS PR01415 Ankyrin repeat signature 158 173 3.8E-6 T 11-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFK25_11060 71be4d9e2c56f24c83fc7de60f40dd61 282 PRINTS PR01415 Ankyrin repeat signature 239 253 3.8E-6 T 11-10-2018 IPR002110 Ankyrin repeat GO:0005515 AFK25_11060 71be4d9e2c56f24c83fc7de60f40dd61 282 Gene3D G3DSA:1.25.40.20 19 93 8.7E-7 T 11-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily AFK25_11060 71be4d9e2c56f24c83fc7de60f40dd61 282 SUPERFAMILY SSF48403 28 279 3.85E-60 T 11-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily AFK25_11060 71be4d9e2c56f24c83fc7de60f40dd61 282 Pfam PF12796 Ankyrin repeats (3 copies) 189 254 4.1E-14 T 11-10-2018 IPR020683 Ankyrin repeat-containing domain AFK25_11060 71be4d9e2c56f24c83fc7de60f40dd61 282 Pfam PF12796 Ankyrin repeats (3 copies) 103 186 5.1E-14 T 11-10-2018 IPR020683 Ankyrin repeat-containing domain AFK25_11060 71be4d9e2c56f24c83fc7de60f40dd61 282 Gene3D G3DSA:1.25.40.20 94 197 8.8E-30 T 11-10-2018 IPR036770 Ankyrin repeat-containing domain superfamily AFK25_06415 4cfb4e253bbeaa96d4d5dad8fb5be7f8 234 PIRSF PIRSF006232 1 232 6.4E-52 T 11-10-2018 IPR012093 Pirin Reactome: R-HSA-8935690 AFK25_06415 4cfb4e253bbeaa96d4d5dad8fb5be7f8 234 SUPERFAMILY SSF51182 1 233 8.81E-69 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily AFK25_06415 4cfb4e253bbeaa96d4d5dad8fb5be7f8 234 Gene3D G3DSA:2.60.120.10 11 135 2.4E-84 T 11-10-2018 IPR014710 RmlC-like jelly roll fold AFK25_06415 4cfb4e253bbeaa96d4d5dad8fb5be7f8 234 Gene3D G3DSA:2.60.120.10 7 234 2.4E-84 T 11-10-2018 IPR014710 RmlC-like jelly roll fold AFK25_06415 4cfb4e253bbeaa96d4d5dad8fb5be7f8 234 Pfam PF02678 Pirin 13 118 2.5E-34 T 11-10-2018 IPR003829 Pirin, N-terminal domain Reactome: R-HSA-8935690 AFK25_11215 de2f2ef4c4f92bd1076a3ae91d53926a 255 SUPERFAMILY SSF55666 153 237 1.7E-22 T 11-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFK25_11215 de2f2ef4c4f92bd1076a3ae91d53926a 255 TIGRFAM TIGR01966 RNasePH: ribonuclease PH 2 237 4.6E-116 T 11-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 AFK25_11215 de2f2ef4c4f92bd1076a3ae91d53926a 255 Pfam PF03725 3' exoribonuclease family, domain 2 160 225 4.9E-9 T 11-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFK25_11215 de2f2ef4c4f92bd1076a3ae91d53926a 255 SUPERFAMILY SSF54211 1 182 1.92E-43 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFK25_11215 de2f2ef4c4f92bd1076a3ae91d53926a 255 ProSitePatterns PS01277 Ribonuclease PH signature. 116 128 - T 11-10-2018 IPR018336 Ribonuclease PH, conserved site AFK25_11215 de2f2ef4c4f92bd1076a3ae91d53926a 255 Hamap MF_00564 Ribonuclease PH [rph]. 11 238 43.815 T 11-10-2018 IPR002381 Ribonuclease PH, bacterial-type GO:0000049|GO:0008033|GO:0009022 AFK25_11215 de2f2ef4c4f92bd1076a3ae91d53926a 255 Pfam PF01138 3' exoribonuclease family, domain 1 10 139 7.6E-23 T 11-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFK25_11215 de2f2ef4c4f92bd1076a3ae91d53926a 255 Gene3D G3DSA:3.30.230.70 9 238 2.2E-59 T 11-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AFK25_05230 bf0d8c4639c9b7bd55d669e29f9c4efb 302 Gene3D G3DSA:3.30.465.10 89 216 3.8E-47 T 11-10-2018 IPR016169 FAD-binding, type PCMH, subdomain 2 AFK25_05230 bf0d8c4639c9b7bd55d669e29f9c4efb 302 SUPERFAMILY SSF56176 22 210 1.27E-41 T 11-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AFK25_05230 bf0d8c4639c9b7bd55d669e29f9c4efb 302 Hamap MF_00037 UDP-N-acetylenolpyruvoylglucosamine reductase [murB]. 1 302 90.456 T 11-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFK25_05230 bf0d8c4639c9b7bd55d669e29f9c4efb 302 Gene3D G3DSA:3.90.78.10 217 302 6.3E-36 T 11-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFK25_05230 bf0d8c4639c9b7bd55d669e29f9c4efb 302 Gene3D G3DSA:3.30.43.10 1 88 1.1E-28 T 11-10-2018 IPR016167 FAD-binding, type PCMH, subdomain 1 AFK25_05230 bf0d8c4639c9b7bd55d669e29f9c4efb 302 SUPERFAMILY SSF56194 196 300 4.58E-38 T 11-10-2018 IPR036635 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain superfamily GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFK25_05230 bf0d8c4639c9b7bd55d669e29f9c4efb 302 Pfam PF01565 FAD binding domain 35 164 8.4E-23 T 11-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AFK25_05230 bf0d8c4639c9b7bd55d669e29f9c4efb 302 Pfam PF02873 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain 201 299 6.0E-31 T 11-10-2018 IPR011601 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFK25_05230 bf0d8c4639c9b7bd55d669e29f9c4efb 302 TIGRFAM TIGR00179 murB: UDP-N-acetylenolpyruvoylglucosamine reductase 22 300 6.3E-101 T 11-10-2018 IPR003170 UDP-N-acetylenolpyruvoylglucosamine reductase GO:0008762|GO:0055114 KEGG: 00520+1.3.1.98|KEGG: 00550+1.3.1.98|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFK25_01630 541a557dd6f2a6e07a0438de08512688 349 SMART SM00388 129 195 2.1E-16 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_01630 541a557dd6f2a6e07a0438de08512688 349 SUPERFAMILY SSF55874 184 349 1.57E-47 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_01630 541a557dd6f2a6e07a0438de08512688 349 SMART SM00387 239 349 2.4E-40 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_01630 541a557dd6f2a6e07a0438de08512688 349 SUPERFAMILY SSF47384 112 195 1.02E-17 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFK25_01630 541a557dd6f2a6e07a0438de08512688 349 Gene3D G3DSA:3.30.565.10 202 349 3.0E-48 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_01630 541a557dd6f2a6e07a0438de08512688 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 329 8.9E-20 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_01630 541a557dd6f2a6e07a0438de08512688 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 294 304 8.9E-20 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_01630 541a557dd6f2a6e07a0438de08512688 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 276 290 8.9E-20 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_01630 541a557dd6f2a6e07a0438de08512688 349 PRINTS PR00344 Bacterial sensor protein C-terminal signature 335 348 8.9E-20 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_01630 541a557dd6f2a6e07a0438de08512688 349 Pfam PF00512 His Kinase A (phospho-acceptor) domain 129 194 6.0E-14 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_01630 541a557dd6f2a6e07a0438de08512688 349 Gene3D G3DSA:1.10.287.130 79 190 1.2E-21 T 11-10-2018 AFK25_01630 541a557dd6f2a6e07a0438de08512688 349 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 240 349 6.6E-30 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_12735 05b28e25a148258fca20e1f9ac5ad3d5 434 TIGRFAM TIGR01981 sufD: FeS assembly protein SufD 151 425 3.1E-75 T 11-10-2018 IPR011542 SUF system FeS cluster assembly, SufD GO:0016226 AFK25_12735 05b28e25a148258fca20e1f9ac5ad3d5 434 Pfam PF01458 Uncharacterized protein family (UPF0051) 184 408 5.2E-62 T 11-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 AFK25_12735 05b28e25a148258fca20e1f9ac5ad3d5 434 SUPERFAMILY SSF101960 13 433 3.27E-119 T 11-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily AFK25_12020 8cfcacdd8786705ee6aa9d791c602a56 240 Gene3D G3DSA:3.30.70.1560 130 213 4.7E-59 T 11-10-2018 AFK25_12020 8cfcacdd8786705ee6aa9d791c602a56 240 Pfam PF01479 S4 domain 3 48 3.6E-10 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_12020 8cfcacdd8786705ee6aa9d791c602a56 240 SUPERFAMILY SSF55120 46 234 4.48E-45 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_12020 8cfcacdd8786705ee6aa9d791c602a56 240 Gene3D G3DSA:3.30.70.580 63 231 4.7E-59 T 11-10-2018 AFK25_12020 8cfcacdd8786705ee6aa9d791c602a56 240 ProSitePatterns PS01149 Rsu family of pseudouridine synthase signature. 101 115 - T 11-10-2018 IPR018496 Pseudouridine synthase, RsuA/RluB/E/F, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0016866 AFK25_12020 8cfcacdd8786705ee6aa9d791c602a56 240 TIGRFAM TIGR00093 TIGR00093: pseudouridine synthase 67 228 3.4E-48 T 11-10-2018 IPR000748 Pseudouridine synthase, RsuA/RluB/E/F GO:0001522|GO:0003723|GO:0009451|GO:0016866 AFK25_12020 8cfcacdd8786705ee6aa9d791c602a56 240 SUPERFAMILY SSF55174 2 59 2.35E-12 T 11-10-2018 AFK25_12020 8cfcacdd8786705ee6aa9d791c602a56 240 Gene3D G3DSA:3.10.290.10 1 59 1.2E-16 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFK25_12020 8cfcacdd8786705ee6aa9d791c602a56 240 SMART SM00363 2 60 1.4E-8 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_12020 8cfcacdd8786705ee6aa9d791c602a56 240 Pfam PF00849 RNA pseudouridylate synthase 63 196 1.8E-19 T 11-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_07990 320a5758a823c61ec7c2b0507d6d1805 396 Gene3D G3DSA:1.20.1250.20 2 389 7.3E-35 T 11-10-2018 AFK25_07990 320a5758a823c61ec7c2b0507d6d1805 396 Pfam PF07690 Major Facilitator Superfamily 10 343 1.1E-24 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFK25_07990 320a5758a823c61ec7c2b0507d6d1805 396 SUPERFAMILY SSF103473 3 390 8.24E-39 T 11-10-2018 IPR036259 MFS transporter superfamily AFK25_05285 163e88823729683c0394f8bdd43769f2 267 TIGRFAM TIGR00726 TIGR00726: YfiH family protein 32 265 4.0E-65 T 11-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase AFK25_05285 163e88823729683c0394f8bdd43769f2 267 SUPERFAMILY SSF64438 15 266 1.37E-83 T 11-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic AFK25_05285 163e88823729683c0394f8bdd43769f2 267 Gene3D G3DSA:3.60.140.10 1 267 6.4E-97 T 11-10-2018 IPR038371 Multi-copper polyphenol oxidoreductase superfamily AFK25_05285 163e88823729683c0394f8bdd43769f2 267 Pfam PF02578 Multi-copper polyphenol oxidoreductase laccase 26 264 5.7E-77 T 11-10-2018 IPR003730 Multi-copper polyphenol oxidoreductase AFK25_14135 f56c2f3599a0fd633f6c98e823ddac10 147 TIGRFAM TIGR02728 spore_gerQ: spore coat protein GerQ 54 135 2.2E-45 T 11-10-2018 IPR014099 Spore coat protein GerQ AFK25_14135 f56c2f3599a0fd633f6c98e823ddac10 147 PIRSF PIRSF038931 1 147 9.7E-55 T 11-10-2018 IPR014099 Spore coat protein GerQ AFK25_14135 f56c2f3599a0fd633f6c98e823ddac10 147 Pfam PF09671 Spore coat protein (Spore_GerQ) 56 131 1.3E-42 T 11-10-2018 IPR014099 Spore coat protein GerQ AFK25_11840 4213e393b1fb1131f63104980c8567ff 200 Gene3D G3DSA:3.10.290.10 91 185 8.7E-80 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFK25_11840 4213e393b1fb1131f63104980c8567ff 200 TIGRFAM TIGR01017 rpsD_bact: ribosomal protein uS4 3 200 4.0E-89 T 11-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFK25_11840 4213e393b1fb1131f63104980c8567ff 200 Hamap MF_01306_B 30S ribosomal protein S4 [rpsD]. 1 200 37.514 T 11-10-2018 IPR005709 Ribosomal protein S4, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFK25_11840 4213e393b1fb1131f63104980c8567ff 200 ProSitePatterns PS00632 Ribosomal protein S4 signature. 90 114 - T 11-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_11840 4213e393b1fb1131f63104980c8567ff 200 SUPERFAMILY SSF55174 2 200 1.15E-72 T 11-10-2018 AFK25_11840 4213e393b1fb1131f63104980c8567ff 200 SMART SM00363 92 156 8.0E-21 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_11840 4213e393b1fb1131f63104980c8567ff 200 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 3 91 2.9E-31 T 11-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 AFK25_11840 4213e393b1fb1131f63104980c8567ff 200 Gene3D G3DSA:1.10.1050.10 6 200 8.7E-80 T 11-10-2018 AFK25_11840 4213e393b1fb1131f63104980c8567ff 200 Pfam PF01479 S4 domain 93 139 5.2E-22 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_11840 4213e393b1fb1131f63104980c8567ff 200 SMART SM01390 3 91 6.4E-49 T 11-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 AFK25_03995 d1eb8cb7c68fbd730ceeeb61f07ff57c 145 Gene3D G3DSA:3.40.630.30 5 135 1.9E-27 T 11-10-2018 AFK25_03995 d1eb8cb7c68fbd730ceeeb61f07ff57c 145 SUPERFAMILY SSF55729 1 137 3.6E-26 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFK25_03995 d1eb8cb7c68fbd730ceeeb61f07ff57c 145 Pfam PF13673 Acetyltransferase (GNAT) domain 34 136 5.7E-18 T 11-10-2018 IPR000182 GNAT domain AFK25_10610 fd87a9fa5fa2cc1c2a61aa425e39459c 307 SUPERFAMILY SSF53686 1 301 1.11E-92 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFK25_10610 fd87a9fa5fa2cc1c2a61aa425e39459c 307 Gene3D G3DSA:3.40.50.1100 45 146 2.5E-116 T 11-10-2018 AFK25_10610 fd87a9fa5fa2cc1c2a61aa425e39459c 307 Gene3D G3DSA:3.40.50.1100 10 299 2.5E-116 T 11-10-2018 AFK25_10610 fd87a9fa5fa2cc1c2a61aa425e39459c 307 ProSitePatterns PS00901 Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. 33 51 - T 11-10-2018 IPR001216 Cysteine synthase/cystathionine beta-synthase, pyridoxal-phosphate attachment site GO:0006535 AFK25_10610 fd87a9fa5fa2cc1c2a61aa425e39459c 307 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 10 292 1.8E-68 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFK25_06200 013dbd3ffbc26efba712c477f6a0fd36 549 SUPERFAMILY SSF52540 67 229 1.49E-5 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_06200 013dbd3ffbc26efba712c477f6a0fd36 549 Gene3D G3DSA:3.40.50.300 244 415 1.1E-36 T 11-10-2018 AFK25_06200 013dbd3ffbc26efba712c477f6a0fd36 549 SUPERFAMILY SSF52540 247 496 8.7E-49 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_06200 013dbd3ffbc26efba712c477f6a0fd36 549 SMART SM00382 281 416 1.1E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_06200 013dbd3ffbc26efba712c477f6a0fd36 549 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 285 413 7.2E-27 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFK25_06200 013dbd3ffbc26efba712c477f6a0fd36 549 Gene3D G3DSA:1.10.8.60 416 493 2.0E-11 T 11-10-2018 AFK25_10440 4aff2253fa9431a65a698f16750d6256 742 Pfam PF00753 Metallo-beta-lactamase superfamily 485 694 6.9E-12 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_10440 4aff2253fa9431a65a698f16750d6256 742 SUPERFAMILY SSF56281 479 732 4.2E-50 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_10440 4aff2253fa9431a65a698f16750d6256 742 Pfam PF13567 Domain of unknown function (DUF4131) 17 154 1.6E-14 T 11-10-2018 IPR025405 Domain of unknown function DUF4131 AFK25_10440 4aff2253fa9431a65a698f16750d6256 742 TIGRFAM TIGR00360 ComEC_N-term: ComEC/Rec2-related protein 218 383 1.7E-39 T 11-10-2018 IPR004477 ComEC/Rec2-related protein AFK25_10440 4aff2253fa9431a65a698f16750d6256 742 TIGRFAM TIGR00361 ComEC_Rec2: DNA internalization-related competence protein ComEC/Rec2 78 724 1.5E-135 T 11-10-2018 IPR004797 Competence protein ComEC/Rec2 GO:0016021|GO:0030420 AFK25_10440 4aff2253fa9431a65a698f16750d6256 742 SMART SM00849 487 695 1.6E-8 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_10440 4aff2253fa9431a65a698f16750d6256 742 Gene3D G3DSA:3.60.15.10 476 739 4.6E-70 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_10440 4aff2253fa9431a65a698f16750d6256 742 Pfam PF03772 Competence protein 196 449 2.4E-59 T 11-10-2018 IPR004477 ComEC/Rec2-related protein AFK25_00385 6d72a77c90aaebf1ca8e9e315a53f0c9 295 Gene3D G3DSA:3.55.30.10 2 234 1.0E-97 T 11-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 AFK25_00385 6d72a77c90aaebf1ca8e9e315a53f0c9 295 Hamap MF_00117 33 kDa chaperonin [hslO]. 2 292 43.572 T 11-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 AFK25_00385 6d72a77c90aaebf1ca8e9e315a53f0c9 295 Pfam PF01430 Hsp33 protein 3 281 4.3E-94 T 11-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 AFK25_00385 6d72a77c90aaebf1ca8e9e315a53f0c9 295 SUPERFAMILY SSF64397 3 242 1.26E-81 T 11-10-2018 IPR016153 Heat shock protein Hsp33, N-terminal GO:0005737|GO:0006457|GO:0051082 AFK25_00385 6d72a77c90aaebf1ca8e9e315a53f0c9 295 PIRSF PIRSF005261 1 293 2.3E-83 T 11-10-2018 IPR000397 Heat shock protein Hsp33 GO:0005737|GO:0006457|GO:0051082 AFK25_00385 6d72a77c90aaebf1ca8e9e315a53f0c9 295 SUPERFAMILY SSF118352 232 289 6.54E-22 T 11-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 AFK25_00385 6d72a77c90aaebf1ca8e9e315a53f0c9 295 Gene3D G3DSA:3.90.1280.10 235 292 5.5E-24 T 11-10-2018 IPR016154 Heat shock protein Hsp33, C-terminal GO:0005737|GO:0006457|GO:0051082 AFK25_10720 2160979a94ee2a5148c75cd57fbed972 138 ProSitePatterns PS01332 Rrf2-type HTH domain signature. 49 67 - T 11-10-2018 IPR030489 Transcription regulator Rrf2-type, conserved site AFK25_10720 2160979a94ee2a5148c75cd57fbed972 138 Gene3D G3DSA:1.10.10.10 1 138 2.2E-52 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_10720 2160979a94ee2a5148c75cd57fbed972 138 TIGRFAM TIGR00738 rrf2_super: Rrf2 family protein 2 124 3.1E-35 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type AFK25_10720 2160979a94ee2a5148c75cd57fbed972 138 SUPERFAMILY SSF46785 2 127 4.45E-33 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_10720 2160979a94ee2a5148c75cd57fbed972 138 Pfam PF02082 Transcriptional regulator 1 82 1.5E-27 T 11-10-2018 IPR000944 Transcription regulator Rrf2-type AFK25_00360 d29dc34658be48098c11ff0da7f31820 316 SMART SM00220 27 272 1.4E-8 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFK25_00360 d29dc34658be48098c11ff0da7f31820 316 Gene3D G3DSA:3.30.200.20 19 109 5.6E-28 T 11-10-2018 AFK25_00360 d29dc34658be48098c11ff0da7f31820 316 Pfam PF00069 Protein kinase domain 27 267 2.9E-19 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFK25_00360 d29dc34658be48098c11ff0da7f31820 316 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 33 54 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFK25_00360 d29dc34658be48098c11ff0da7f31820 316 Gene3D G3DSA:1.10.510.10 110 263 5.6E-28 T 11-10-2018 AFK25_00360 d29dc34658be48098c11ff0da7f31820 316 SUPERFAMILY SSF56112 11 234 7.96E-32 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily AFK25_01465 0e572531b7e1629d93f436ec29198b3b 210 Pfam PF04012 PspA/IM30 family 2 206 2.2E-34 T 11-10-2018 IPR007157 PspA/IM30 AFK25_04170 47b4c4df271fbfab094dd8e5e92239b9 251 Gene3D G3DSA:1.10.510.10 9 248 4.9E-50 T 11-10-2018 AFK25_04170 47b4c4df271fbfab094dd8e5e92239b9 251 SMART SM00219 18 243 7.7E-7 T 11-10-2018 IPR020635 Tyrosine-protein kinase, catalytic domain GO:0004713|GO:0006468 AFK25_04170 47b4c4df271fbfab094dd8e5e92239b9 251 ProSitePatterns PS00107 Protein kinases ATP-binding region signature. 24 47 - T 11-10-2018 IPR017441 Protein kinase, ATP binding site GO:0005524 AFK25_04170 47b4c4df271fbfab094dd8e5e92239b9 251 Pfam PF00069 Protein kinase domain 18 207 2.2E-36 T 11-10-2018 IPR000719 Protein kinase domain GO:0004672|GO:0005524|GO:0006468 AFK25_04170 47b4c4df271fbfab094dd8e5e92239b9 251 SUPERFAMILY SSF56112 6 245 2.83E-53 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily AFK25_00655 72083decca9f637d870fdeba9b4583e4 122 TIGRFAM TIGR01067 rplN_bact: ribosomal protein uL14 1 122 2.7E-58 T 11-10-2018 IPR005745 Ribosomal protein L14P, bacterial-type GO:0003735|GO:0006412|GO:0015934 AFK25_00655 72083decca9f637d870fdeba9b4583e4 122 SUPERFAMILY SSF50193 1 122 1.7E-51 T 11-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 AFK25_00655 72083decca9f637d870fdeba9b4583e4 122 ProSitePatterns PS00049 Ribosomal protein L14 signature. 60 86 - T 11-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00655 72083decca9f637d870fdeba9b4583e4 122 Pfam PF00238 Ribosomal protein L14p/L23e 1 122 7.7E-55 T 11-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AFK25_00655 72083decca9f637d870fdeba9b4583e4 122 Gene3D G3DSA:2.40.150.20 1 122 2.5E-53 T 11-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 AFK25_00655 72083decca9f637d870fdeba9b4583e4 122 SMART SM01374 1 122 1.8E-86 T 11-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AFK25_00655 72083decca9f637d870fdeba9b4583e4 122 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 1 122 26.107 T 11-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AFK25_12280 14c71682bfc0a4a952f71fe02c0532e6 451 PRINTS PR00095 Anthranilate synthase component I signature 288 301 6.1E-6 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFK25_12280 14c71682bfc0a4a952f71fe02c0532e6 451 PRINTS PR00095 Anthranilate synthase component I signature 302 315 6.1E-6 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFK25_12280 14c71682bfc0a4a952f71fe02c0532e6 451 PRINTS PR00095 Anthranilate synthase component I signature 380 394 6.1E-6 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFK25_12280 14c71682bfc0a4a952f71fe02c0532e6 451 PRINTS PR00095 Anthranilate synthase component I signature 395 409 6.1E-6 T 11-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AFK25_12280 14c71682bfc0a4a952f71fe02c0532e6 451 Hamap MF_01935 Isochorismate synthase MenF [menF]. 1 448 31.628 T 11-10-2018 IPR034681 Isochorismate synthase MenF GO:0008909|GO:0009234 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 AFK25_12280 14c71682bfc0a4a952f71fe02c0532e6 451 Pfam PF00425 chorismate binding enzyme 185 438 2.2E-82 T 11-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal AFK25_12280 14c71682bfc0a4a952f71fe02c0532e6 451 SUPERFAMILY SSF56322 46 447 2.75E-110 T 11-10-2018 IPR005801 ADC synthase GO:0009058 AFK25_12280 14c71682bfc0a4a952f71fe02c0532e6 451 Gene3D G3DSA:3.60.120.10 2 449 3.1E-120 T 11-10-2018 IPR005801 ADC synthase GO:0009058 AFK25_12280 14c71682bfc0a4a952f71fe02c0532e6 451 TIGRFAM TIGR00543 isochor_syn: isochorismate synthase 103 445 5.4E-115 T 11-10-2018 IPR004561 Isochorismate synthase GO:0008909|GO:0009058 KEGG: 00130+5.4.4.2|MetaCyc: PWY-5837|MetaCyc: PWY-5901|MetaCyc: PWY-6406 AFK25_12055 b272463f837c53f8a1867a072e71e543 317 TIGRFAM TIGR01212 TIGR01212: radical SAM protein, TIGR01212 family 12 311 1.5E-138 T 11-10-2018 IPR005911 Protein YhcC-like GO:0051536 AFK25_12055 b272463f837c53f8a1867a072e71e543 317 Pfam PF04055 Radical SAM superfamily 49 210 6.2E-14 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFK25_12055 b272463f837c53f8a1867a072e71e543 317 SUPERFAMILY SSF102114 5 311 1.14E-56 T 11-10-2018 AFK25_12055 b272463f837c53f8a1867a072e71e543 317 SMART SM00729 29 256 1.5E-39 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFK25_12055 b272463f837c53f8a1867a072e71e543 317 Pfam PF16199 Radical_SAM C-terminal domain 217 300 2.9E-25 T 11-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 AFK25_12055 b272463f837c53f8a1867a072e71e543 317 Gene3D G3DSA:3.80.30.20 47 243 1.3E-14 T 11-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFK25_09235 7411f5171e1e6e8a34e1289c14cab763 173 SUPERFAMILY SSF52833 9 170 1.26E-44 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_09235 7411f5171e1e6e8a34e1289c14cab763 173 Gene3D G3DSA:3.40.30.10 28 173 4.3E-50 T 11-10-2018 AFK25_09235 7411f5171e1e6e8a34e1289c14cab763 173 Pfam PF00578 AhpC/TSA family 37 152 3.6E-36 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFK25_13650 c660288ce3aa303d652bcb37431b2572 433 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 312 412 6.4E-31 T 11-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFK25_13650 c660288ce3aa303d652bcb37431b2572 433 Gene3D G3DSA:1.20.5.100 196 227 4.5E-20 T 11-10-2018 AFK25_13650 c660288ce3aa303d652bcb37431b2572 433 PIRSF PIRSF000124 1 429 2.2E-151 T 11-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFK25_13650 c660288ce3aa303d652bcb37431b2572 433 SUPERFAMILY SSF51735 1 187 2.37E-53 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_13650 c660288ce3aa303d652bcb37431b2572 433 PIRSF PIRSF500134 1 432 2.4E-179 T 11-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 AFK25_13650 c660288ce3aa303d652bcb37431b2572 433 SUPERFAMILY SSF48179 196 291 1.43E-33 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFK25_13650 c660288ce3aa303d652bcb37431b2572 433 SUPERFAMILY SSF52413 299 425 1.44E-35 T 11-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 AFK25_13650 c660288ce3aa303d652bcb37431b2572 433 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 197 289 4.0E-40 T 11-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFK25_13650 c660288ce3aa303d652bcb37431b2572 433 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 1 410 7.6E-142 T 11-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AFK25_13650 c660288ce3aa303d652bcb37431b2572 433 Gene3D G3DSA:3.40.50.720 1 195 8.4E-75 T 11-10-2018 AFK25_13650 c660288ce3aa303d652bcb37431b2572 433 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 1 182 2.1E-65 T 11-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFK25_13650 c660288ce3aa303d652bcb37431b2572 433 Gene3D G3DSA:3.40.50.720 228 433 7.9E-75 T 11-10-2018 AFK25_13650 c660288ce3aa303d652bcb37431b2572 433 SMART SM00984 312 414 2.2E-45 T 11-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 Gene3D G3DSA:1.10.1030.10 406 549 2.3E-42 T 11-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 9.7E-63 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 9.7E-63 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 378 396 9.7E-63 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 9.7E-63 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 9.7E-63 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 9.7E-63 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 296 325 9.7E-63 T 11-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 296 303 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 973 0.0 T 11-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 Gene3D G3DSA:3.30.470.20 120 401 1.3E-124 T 11-10-2018 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 425 543 1.3E-37 T 11-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 829 836 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 Gene3D G3DSA:3.40.50.20 1 116 1.5E-44 T 11-10-2018 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 SUPERFAMILY SSF56059 669 922 4.42E-83 T 11-10-2018 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 SUPERFAMILY SSF52440 553 671 7.19E-46 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 SUPERFAMILY SSF48108 394 548 1.12E-45 T 11-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 Gene3D G3DSA:3.30.1490.20 682 747 4.2E-89 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 SUPERFAMILY SSF52440 1 127 1.41E-46 T 11-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 669 866 4.0E-32 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 333 9.8E-82 T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 Gene3D G3DSA:3.40.50.20 550 658 3.0E-45 T 11-10-2018 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 Gene3D G3DSA:3.30.470.20 663 920 4.2E-89 T 11-10-2018 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 SMART SM01096 420 543 3.7E-56 T 11-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 705 719 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1020 12.449 T 11-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 SUPERFAMILY SSF56059 128 399 2.83E-109 T 11-10-2018 AFK25_03390 0b90d1a1fca7c0146bace7a6b053590a 1034 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 11-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AFK25_04385 0c346b374a04fd0f5d5ea954bbff4ef6 389 Pfam PF01636 Phosphotransferase enzyme family 28 261 7.6E-15 T 11-10-2018 IPR002575 Aminoglycoside phosphotransferase AFK25_04385 0c346b374a04fd0f5d5ea954bbff4ef6 389 Gene3D G3DSA:3.30.200.20 1 112 8.4E-46 T 11-10-2018 AFK25_04385 0c346b374a04fd0f5d5ea954bbff4ef6 389 Hamap MF_01683 Methylthioribose kinase [mtnK]. 1 389 190.523 T 11-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 AFK25_04385 0c346b374a04fd0f5d5ea954bbff4ef6 389 Gene3D G3DSA:3.90.1200.10 113 387 4.5E-107 T 11-10-2018 AFK25_04385 0c346b374a04fd0f5d5ea954bbff4ef6 389 TIGRFAM TIGR01767 MTRK: S-methyl-5-thioribose kinase 29 381 1.0E-147 T 11-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 AFK25_04385 0c346b374a04fd0f5d5ea954bbff4ef6 389 PIRSF PIRSF031134 1 387 1.5E-154 T 11-10-2018 IPR009212 Methylthioribose kinase GO:0009086|GO:0046522 KEGG: 00270+2.7.1.100|MetaCyc: PWY-6754 AFK25_04385 0c346b374a04fd0f5d5ea954bbff4ef6 389 SUPERFAMILY SSF56112 2 373 7.42E-91 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily AFK25_00935 332807753d24e6b59789a183dd653cbb 302 SUPERFAMILY SSF46689 242 294 5.38E-13 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_00935 332807753d24e6b59789a183dd653cbb 302 SUPERFAMILY SSF46689 190 240 8.87E-7 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_00935 332807753d24e6b59789a183dd653cbb 302 Gene3D G3DSA:1.10.10.60 188 239 2.7E-11 T 11-10-2018 AFK25_00935 332807753d24e6b59789a183dd653cbb 302 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 273 289 6.6E-6 T 11-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFK25_00935 332807753d24e6b59789a183dd653cbb 302 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 258 273 6.6E-6 T 11-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFK25_00935 332807753d24e6b59789a183dd653cbb 302 Gene3D G3DSA:2.60.120.10 5 105 3.0E-11 T 11-10-2018 IPR014710 RmlC-like jelly roll fold AFK25_00935 332807753d24e6b59789a183dd653cbb 302 Pfam PF12833 Helix-turn-helix domain 212 291 1.6E-16 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFK25_00935 332807753d24e6b59789a183dd653cbb 302 SUPERFAMILY SSF51215 37 164 8.37E-14 T 11-10-2018 IPR037923 Transcription regulator HTH-like AFK25_00935 332807753d24e6b59789a183dd653cbb 302 Gene3D G3DSA:1.10.10.60 240 297 8.5E-17 T 11-10-2018 AFK25_00935 332807753d24e6b59789a183dd653cbb 302 SMART SM00342 206 289 1.1E-24 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFK25_00935 332807753d24e6b59789a183dd653cbb 302 Pfam PF02311 AraC-like ligand binding domain 36 105 8.5E-12 T 11-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 AFK25_00935 332807753d24e6b59789a183dd653cbb 302 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 243 285 - T 11-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFK25_07180 7ffd4d19ade183bf89b87040239dc361 280 Gene3D G3DSA:3.40.50.10170 1 152 5.5E-57 T 11-10-2018 AFK25_07180 7ffd4d19ade183bf89b87040239dc361 280 Gene3D G3DSA:3.30.1180.10 153 279 5.3E-39 T 11-10-2018 AFK25_07180 7ffd4d19ade183bf89b87040239dc361 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 279 2.1E-97 T 11-10-2018 IPR003797 DegV AFK25_07180 7ffd4d19ade183bf89b87040239dc361 280 SUPERFAMILY SSF82549 1 279 6.28E-96 T 11-10-2018 AFK25_07180 7ffd4d19ade183bf89b87040239dc361 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 278 3.6E-105 T 11-10-2018 IPR003797 DegV AFK25_06150 950e5551799d8dc85cb3cfd4ae554d2c 253 SUPERFAMILY SSF46785 3 73 1.29E-10 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_06150 950e5551799d8dc85cb3cfd4ae554d2c 253 Gene3D G3DSA:1.10.10.10 1 67 1.2E-14 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_06150 950e5551799d8dc85cb3cfd4ae554d2c 253 SUPERFAMILY SSF55781 57 245 9.81E-50 T 11-10-2018 AFK25_06150 950e5551799d8dc85cb3cfd4ae554d2c 253 SMART SM00346 2 89 6.0E-21 T 11-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFK25_06150 950e5551799d8dc85cb3cfd4ae554d2c 253 Pfam PF01614 Bacterial transcriptional regulator 117 241 2.7E-35 T 11-10-2018 IPR014757 Transcription regulator IclR, C-terminal AFK25_06150 950e5551799d8dc85cb3cfd4ae554d2c 253 Gene3D G3DSA:3.30.450.40 68 250 7.1E-55 T 11-10-2018 IPR029016 GAF-like domain superfamily AFK25_06150 950e5551799d8dc85cb3cfd4ae554d2c 253 Pfam PF09339 IclR helix-turn-helix domain 5 53 6.1E-10 T 11-10-2018 IPR005471 Transcription regulator IclR, N-terminal GO:0003677|GO:0006355 AFK25_04005 4de724ac5ab1ff7fe4d9e58f8f0e18ee 140 ProSitePatterns PS00893 Nudix box signature. 42 63 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFK25_04005 4de724ac5ab1ff7fe4d9e58f8f0e18ee 140 PRINTS PR00502 NUDIX hydrolase family signature 37 51 7.5E-6 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFK25_04005 4de724ac5ab1ff7fe4d9e58f8f0e18ee 140 PRINTS PR00502 NUDIX hydrolase family signature 51 66 7.5E-6 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFK25_04005 4de724ac5ab1ff7fe4d9e58f8f0e18ee 140 Pfam PF00293 NUDIX domain 18 116 1.1E-14 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFK25_04005 4de724ac5ab1ff7fe4d9e58f8f0e18ee 140 SUPERFAMILY SSF55811 11 125 6.77E-26 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFK25_04005 4de724ac5ab1ff7fe4d9e58f8f0e18ee 140 Gene3D G3DSA:3.90.79.10 4 133 3.6E-29 T 11-10-2018 AFK25_09215 1452b89763795f81f4df4a19723dc30f 587 Gene3D G3DSA:3.30.565.10 433 587 4.1E-51 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_09215 1452b89763795f81f4df4a19723dc30f 587 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 477 586 7.3E-30 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_09215 1452b89763795f81f4df4a19723dc30f 587 Pfam PF00989 PAS fold 255 355 3.8E-5 T 11-10-2018 IPR013767 PAS fold GO:0006355 AFK25_09215 1452b89763795f81f4df4a19723dc30f 587 SUPERFAMILY SSF158472 196 243 2.88E-10 T 11-10-2018 AFK25_09215 1452b89763795f81f4df4a19723dc30f 587 SUPERFAMILY SSF55874 420 586 5.63E-54 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_09215 1452b89763795f81f4df4a19723dc30f 587 SMART SM00387 476 587 1.1E-41 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_09215 1452b89763795f81f4df4a19723dc30f 587 Gene3D G3DSA:1.20.1480.50 156 249 2.9E-21 T 11-10-2018 AFK25_09215 1452b89763795f81f4df4a19723dc30f 587 Gene3D G3DSA:1.10.287.130 360 432 3.3E-25 T 11-10-2018 AFK25_09215 1452b89763795f81f4df4a19723dc30f 587 Gene3D G3DSA:3.30.450.20 250 359 5.6E-10 T 11-10-2018 AFK25_09215 1452b89763795f81f4df4a19723dc30f 587 Pfam PF00672 HAMP domain 196 243 2.0E-11 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_09215 1452b89763795f81f4df4a19723dc30f 587 SMART SM00304 195 247 6.8E-13 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_09215 1452b89763795f81f4df4a19723dc30f 587 SUPERFAMILY SSF55785 244 356 1.05E-6 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_09215 1452b89763795f81f4df4a19723dc30f 587 SMART SM00388 364 431 6.9E-22 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_09215 1452b89763795f81f4df4a19723dc30f 587 Pfam PF00512 His Kinase A (phospho-acceptor) domain 365 431 1.1E-19 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_09215 1452b89763795f81f4df4a19723dc30f 587 SUPERFAMILY SSF47384 348 432 1.79E-21 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFK25_09215 1452b89763795f81f4df4a19723dc30f 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 513 527 3.0E-20 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_09215 1452b89763795f81f4df4a19723dc30f 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 572 585 3.0E-20 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_09215 1452b89763795f81f4df4a19723dc30f 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 548 566 3.0E-20 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_09215 1452b89763795f81f4df4a19723dc30f 587 PRINTS PR00344 Bacterial sensor protein C-terminal signature 531 541 3.0E-20 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_14070 2007c4795171cbef003bf9091e28a09a 222 Pfam PF02163 Peptidase family M50 116 190 1.5E-9 T 11-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 AFK25_09965 64f6367a7140144e1455e64a9791a465 123 Pfam PF00581 Rhodanese-like domain 39 117 6.9E-20 T 11-10-2018 IPR001763 Rhodanese-like domain AFK25_09965 64f6367a7140144e1455e64a9791a465 123 Gene3D G3DSA:3.40.250.10 27 123 3.8E-31 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_09965 64f6367a7140144e1455e64a9791a465 123 SMART SM00450 27 122 3.4E-29 T 11-10-2018 IPR001763 Rhodanese-like domain AFK25_09965 64f6367a7140144e1455e64a9791a465 123 SUPERFAMILY SSF52821 4 118 4.98E-37 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_05960 0956a38e5f77d0c9393213136b0b516a 289 Pfam PF00701 Dihydrodipicolinate synthetase family 4 288 9.4E-116 T 11-10-2018 IPR002220 DapA-like GO:0016829 AFK25_05960 0956a38e5f77d0c9393213136b0b516a 289 Gene3D G3DSA:3.20.20.70 1 289 1.4E-121 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_05960 0956a38e5f77d0c9393213136b0b516a 289 SMART SM01130 3 289 1.2E-142 T 11-10-2018 IPR002220 DapA-like GO:0016829 AFK25_05960 0956a38e5f77d0c9393213136b0b516a 289 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 135 165 - T 11-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 AFK25_05960 0956a38e5f77d0c9393213136b0b516a 289 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 3 289 65.928 T 11-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFK25_05960 0956a38e5f77d0c9393213136b0b516a 289 SUPERFAMILY SSF51569 5 288 5.44E-107 T 11-10-2018 AFK25_05960 0956a38e5f77d0c9393213136b0b516a 289 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 40 57 - T 11-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFK25_05960 0956a38e5f77d0c9393213136b0b516a 289 PIRSF PIRSF001365 2 289 1.7E-102 T 11-10-2018 IPR002220 DapA-like GO:0016829 AFK25_05960 0956a38e5f77d0c9393213136b0b516a 289 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 7 288 1.3E-115 T 11-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFK25_05960 0956a38e5f77d0c9393213136b0b516a 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 105 121 1.5E-34 T 11-10-2018 IPR002220 DapA-like GO:0016829 AFK25_05960 0956a38e5f77d0c9393213136b0b516a 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 73 91 1.5E-34 T 11-10-2018 IPR002220 DapA-like GO:0016829 AFK25_05960 0956a38e5f77d0c9393213136b0b516a 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 130 147 1.5E-34 T 11-10-2018 IPR002220 DapA-like GO:0016829 AFK25_05960 0956a38e5f77d0c9393213136b0b516a 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 37 58 1.5E-34 T 11-10-2018 IPR002220 DapA-like GO:0016829 AFK25_01395 ca90f1279151932ad0426261ee75dd40 570 Pfam PF01979 Amidohydrolase family 60 343 4.8E-36 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFK25_01395 ca90f1279151932ad0426261ee75dd40 570 Pfam PF13382 Adenine deaminase C-terminal domain 397 564 6.5E-64 T 11-10-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 AFK25_01395 ca90f1279151932ad0426261ee75dd40 570 TIGRFAM TIGR01178 ade: adenine deaminase 14 567 4.9E-204 T 11-10-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 AFK25_01395 ca90f1279151932ad0426261ee75dd40 570 Gene3D G3DSA:3.20.20.140 64 307 6.4E-134 T 11-10-2018 AFK25_01395 ca90f1279151932ad0426261ee75dd40 570 SUPERFAMILY SSF51338 5 357 2.04E-21 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFK25_01395 ca90f1279151932ad0426261ee75dd40 570 Hamap MF_01518 Adenine deaminase [ade]. 14 567 40.205 T 11-10-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 AFK25_01395 ca90f1279151932ad0426261ee75dd40 570 Gene3D G3DSA:2.30.40.10 6 344 6.4E-134 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFK25_01395 ca90f1279151932ad0426261ee75dd40 570 SUPERFAMILY SSF51556 64 312 5.21E-42 T 11-10-2018 IPR032466 Metal-dependent hydrolase AFK25_03700 4db347f288801a0e0c02f4fe38d9247a 707 SUPERFAMILY SSF52540 93 697 3.48E-130 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_03700 4db347f288801a0e0c02f4fe38d9247a 707 Pfam PF13361 UvrD-like helicase C-terminal domain 358 491 7.3E-18 T 11-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFK25_03700 4db347f288801a0e0c02f4fe38d9247a 707 Gene3D G3DSA:3.40.50.300 361 694 2.1E-73 T 11-10-2018 AFK25_03700 4db347f288801a0e0c02f4fe38d9247a 707 Pfam PF13361 UvrD-like helicase C-terminal domain 611 681 7.7E-24 T 11-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFK25_03700 4db347f288801a0e0c02f4fe38d9247a 707 Gene3D G3DSA:1.10.10.160 195 270 3.5E-76 T 11-10-2018 IPR013986 DExx box DNA helicase domain superfamily AFK25_03700 4db347f288801a0e0c02f4fe38d9247a 707 ProSitePatterns PS00202 Rubredoxin signature. 29 39 - T 11-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 AFK25_03700 4db347f288801a0e0c02f4fe38d9247a 707 Gene3D G3DSA:3.40.50.300 95 353 3.5E-76 T 11-10-2018 AFK25_03700 4db347f288801a0e0c02f4fe38d9247a 707 Pfam PF00580 UvrD/REP helicase N-terminal domain 96 352 4.1E-54 T 11-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 AFK25_03700 4db347f288801a0e0c02f4fe38d9247a 707 Gene3D G3DSA:1.10.486.10 462 601 2.1E-73 T 11-10-2018 AFK25_07845 3a669a190836cc7cf61c8f109f935701 101 Pfam PF01022 Bacterial regulatory protein, arsR family 25 71 2.4E-17 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_07845 3a669a190836cc7cf61c8f109f935701 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 20 35 2.1E-15 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_07845 3a669a190836cc7cf61c8f109f935701 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 67 82 2.1E-15 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_07845 3a669a190836cc7cf61c8f109f935701 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 52 67 2.1E-15 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_07845 3a669a190836cc7cf61c8f109f935701 101 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 50 2.1E-15 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_07845 3a669a190836cc7cf61c8f109f935701 101 SMART SM00418 18 96 4.4E-33 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_07845 3a669a190836cc7cf61c8f109f935701 101 SUPERFAMILY SSF46785 6 97 6.51E-27 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_07845 3a669a190836cc7cf61c8f109f935701 101 Gene3D G3DSA:1.10.10.10 2 101 8.2E-31 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_00245 92c8b4ea62f7292b6174055522405441 89 Pfam PF06257 Biofilm formation stimulator VEG 4 74 1.4E-30 T 11-10-2018 IPR009366 Protein Veg GO:0006355 AFK25_00245 92c8b4ea62f7292b6174055522405441 89 PIRSF PIRSF037257 1 85 1.1E-35 T 11-10-2018 IPR009366 Protein Veg GO:0006355 AFK25_00245 92c8b4ea62f7292b6174055522405441 89 Gene3D G3DSA:2.30.30.100 2 78 8.5E-26 T 11-10-2018 AFK25_13195 f755adc7c3a4cadbc1a0710f55444d5a 245 Pfam PF02348 Cytidylyltransferase 4 210 1.9E-35 T 11-10-2018 IPR003329 Acylneuraminate cytidylyltransferase KEGG: 00540+2.7.7.38|MetaCyc: PWY-1269|Reactome: R-HSA-4085001 AFK25_13195 f755adc7c3a4cadbc1a0710f55444d5a 245 SUPERFAMILY SSF53448 2 205 1.64E-32 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_13195 f755adc7c3a4cadbc1a0710f55444d5a 245 Gene3D G3DSA:3.90.550.10 1 211 6.7E-44 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_07700 b7169a6cc746f66180b8f6d3e3f289ad 49 Pfam PF08113 Cytochrome c oxidase subunit IIa family 21 48 2.6E-5 T 11-10-2018 IPR012538 Cytochrome c oxidase polypeptide 2A KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 AFK25_12305 356968e351b1c0070cee521ebd358933 340 Gene3D G3DSA:3.90.550.10 155 234 8.2E-6 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_12305 356968e351b1c0070cee521ebd358933 340 Gene3D G3DSA:3.90.550.10 3 154 5.9E-24 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_12305 356968e351b1c0070cee521ebd358933 340 Pfam PF00483 Nucleotidyl transferase 19 149 7.6E-9 T 11-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFK25_12305 356968e351b1c0070cee521ebd358933 340 SUPERFAMILY SSF53448 18 296 2.29E-34 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_12305 356968e351b1c0070cee521ebd358933 340 Gene3D G3DSA:2.160.10.10 235 336 9.9E-27 T 11-10-2018 AFK25_12305 356968e351b1c0070cee521ebd358933 340 SUPERFAMILY SSF51161 194 320 3.33E-14 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily AFK25_02460 e406bab03793286e54fef4fa72dbf70b 159 Gene3D G3DSA:2.60.220.40 83 147 3.4E-9 T 11-10-2018 AFK25_02460 e406bab03793286e54fef4fa72dbf70b 159 Pfam PF04717 Type VI secretion system, phage-baseplate injector 10 111 3.3E-14 T 11-10-2018 IPR006531 Gp5 N-terminal AFK25_02460 e406bab03793286e54fef4fa72dbf70b 159 Gene3D G3DSA:2.40.50.230 7 81 1.1E-12 T 11-10-2018 IPR037026 Vgr protein, OB-fold domain superfamily AFK25_02460 e406bab03793286e54fef4fa72dbf70b 159 TIGRFAM TIGR01644 phage_P2_V: phage baseplate assembly protein V 12 129 3.0E-18 T 11-10-2018 IPR013046 Phage baseplate assembly protein V/Gp45 AFK25_12595 5b4a3ba3a9796b9e0803abaae0514369 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 95 113 8.9E-8 T 11-10-2018 AFK25_12595 5b4a3ba3a9796b9e0803abaae0514369 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 8.9E-8 T 11-10-2018 AFK25_12595 5b4a3ba3a9796b9e0803abaae0514369 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 142 160 8.9E-8 T 11-10-2018 AFK25_12595 5b4a3ba3a9796b9e0803abaae0514369 355 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 250 272 8.9E-8 T 11-10-2018 AFK25_12595 5b4a3ba3a9796b9e0803abaae0514369 355 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 283 3.8E-35 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFK25_12595 5b4a3ba3a9796b9e0803abaae0514369 355 SUPERFAMILY SSF51905 62 298 4.34E-25 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_12595 5b4a3ba3a9796b9e0803abaae0514369 355 Gene3D G3DSA:3.50.50.100 1 354 5.3E-75 T 11-10-2018 AFK25_05885 d0858777ef3226422bdbd344616f0d76 99 Gene3D G3DSA:3.30.1330.30 2 99 2.8E-37 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like AFK25_05885 d0858777ef3226422bdbd344616f0d76 99 SUPERFAMILY SSF55315 6 98 2.16E-27 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like AFK25_05885 d0858777ef3226422bdbd344616f0d76 99 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 10 95 1.6E-18 T 11-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 AFK25_03275 421194f5d78e66a27af75630916db8a5 255 TIGRFAM TIGR01465 cobM_cbiF: precorrin-4 C11-methyltransferase 3 251 9.7E-106 T 11-10-2018 IPR006362 Cobalamin (vitamin B12) biosynthesis CobM/CbiF, precorrin-4 C11-methyltransferase GO:0009236|GO:0046026 AFK25_03275 421194f5d78e66a27af75630916db8a5 255 Gene3D G3DSA:3.30.950.10 111 231 1.8E-48 T 11-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFK25_03275 421194f5d78e66a27af75630916db8a5 255 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 6 20 - T 11-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFK25_03275 421194f5d78e66a27af75630916db8a5 255 ProSitePatterns PS00840 Uroporphyrin-III C-methyltransferase signature 2. 76 109 - T 11-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AFK25_03275 421194f5d78e66a27af75630916db8a5 255 SUPERFAMILY SSF53790 2 237 3.79E-68 T 11-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFK25_03275 421194f5d78e66a27af75630916db8a5 255 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 206 1.6E-47 T 11-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFK25_03275 421194f5d78e66a27af75630916db8a5 255 Gene3D G3DSA:3.40.1010.10 1 110 1.8E-33 T 11-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFK25_01385 74765224fc8a2fa7de6ab01ccc70d4d7 515 SUPERFAMILY SSF53720 4 511 1.09E-160 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFK25_01385 74765224fc8a2fa7de6ab01ccc70d4d7 515 Gene3D G3DSA:3.40.605.10 10 511 9.9E-194 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFK25_01385 74765224fc8a2fa7de6ab01ccc70d4d7 515 TIGRFAM TIGR01237 D1pyr5carbox2: putative delta-1-pyrroline-5-carboxylate dehydrogenase 5 515 4.2E-264 T 11-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 AFK25_01385 74765224fc8a2fa7de6ab01ccc70d4d7 515 Gene3D G3DSA:3.40.309.10 290 480 9.9E-194 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFK25_01385 74765224fc8a2fa7de6ab01ccc70d4d7 515 Pfam PF00171 Aldehyde dehydrogenase family 50 511 3.9E-160 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFK25_01385 74765224fc8a2fa7de6ab01ccc70d4d7 515 Hamap MF_00733 1-pyrroline-5-carboxylate dehydrogenase [rocA]. 1 515 71.141 T 11-10-2018 IPR005932 Putative 1-pyrroline-5-carboxylate dehydrogenase, Bacillales KEGG: 00250+1.2.1.88|KEGG: 00330+1.2.1.88|MetaCyc: PWY-6853 AFK25_01385 74765224fc8a2fa7de6ab01ccc70d4d7 515 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 285 292 - T 11-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 AFK25_01385 74765224fc8a2fa7de6ab01ccc70d4d7 515 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 313 324 - T 11-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 AFK25_10030 aa677054c86c6bbc079d2911cb40c9a0 343 Gene3D G3DSA:1.20.81.30 196 308 1.6E-12 T 11-10-2018 AFK25_10030 aa677054c86c6bbc079d2911cb40c9a0 343 Gene3D G3DSA:1.20.81.30 2 111 2.3E-11 T 11-10-2018 AFK25_10030 aa677054c86c6bbc079d2911cb40c9a0 343 Pfam PF00482 Type II secretion system (T2SS), protein F 15 129 2.7E-10 T 11-10-2018 IPR018076 Type II secretion system F domain AFK25_10030 aa677054c86c6bbc079d2911cb40c9a0 343 Pfam PF00482 Type II secretion system (T2SS), protein F 213 335 4.2E-18 T 11-10-2018 IPR018076 Type II secretion system F domain AFK25_09800 8bb94ac0a528d187a25642b8e45fcc7d 425 Pfam PF05580 SpoIVB peptidase S55 201 409 1.2E-86 T 11-10-2018 IPR008763 Peptidase S55, SpoIVB AFK25_09800 8bb94ac0a528d187a25642b8e45fcc7d 425 Pfam PF13180 PDZ domain 133 189 9.3E-8 T 11-10-2018 IPR001478 PDZ domain GO:0005515 AFK25_09800 8bb94ac0a528d187a25642b8e45fcc7d 425 SUPERFAMILY SSF50156 131 194 1.45E-11 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 AFK25_09800 8bb94ac0a528d187a25642b8e45fcc7d 425 Gene3D G3DSA:2.30.42.10 130 210 1.8E-16 T 11-10-2018 AFK25_09800 8bb94ac0a528d187a25642b8e45fcc7d 425 TIGRFAM TIGR02860 spore_IV_B: stage IV sporulation protein B 5 414 2.2E-171 T 11-10-2018 IPR014219 Peptidase S55, sporulation stage IV, protein B AFK25_09800 8bb94ac0a528d187a25642b8e45fcc7d 425 SUPERFAMILY SSF50494 203 407 9.95E-7 T 11-10-2018 IPR009003 Peptidase S1, PA clan AFK25_09800 8bb94ac0a528d187a25642b8e45fcc7d 425 SMART SM00228 108 184 0.0025 T 11-10-2018 IPR001478 PDZ domain GO:0005515 AFK25_04815 cbf31003e6982ca2e97e32bf77ebfc9f 152 SUPERFAMILY SSF54631 21 145 9.03E-31 T 11-10-2018 AFK25_04815 cbf31003e6982ca2e97e32bf77ebfc9f 152 Gene3D G3DSA:3.10.580.10 8 151 3.6E-56 T 11-10-2018 AFK25_04815 cbf31003e6982ca2e97e32bf77ebfc9f 152 Pfam PF00571 CBS domain 25 76 0.0079 T 11-10-2018 IPR000644 CBS domain AFK25_04815 cbf31003e6982ca2e97e32bf77ebfc9f 152 Pfam PF00571 CBS domain 91 142 6.0E-7 T 11-10-2018 IPR000644 CBS domain AFK25_04640 724545377b7bb45e332ec646165b9e72 281 Gene3D G3DSA:1.20.890.100 170 224 8.4E-23 T 11-10-2018 AFK25_04640 724545377b7bb45e332ec646165b9e72 281 Pfam PF00874 PRD domain 186 275 1.5E-20 T 11-10-2018 IPR011608 PRD domain GO:0006355 AFK25_04640 724545377b7bb45e332ec646165b9e72 281 Pfam PF00874 PRD domain 80 167 2.3E-25 T 11-10-2018 IPR011608 PRD domain GO:0006355 AFK25_04640 724545377b7bb45e332ec646165b9e72 281 SUPERFAMILY SSF63520 59 170 3.01E-31 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 AFK25_04640 724545377b7bb45e332ec646165b9e72 281 Gene3D G3DSA:2.30.24.10 1 70 5.0E-28 T 11-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 AFK25_04640 724545377b7bb45e332ec646165b9e72 281 ProSitePatterns PS00654 PRD domain signature. 102 114 - T 11-10-2018 IPR001550 Transcription antiterminator, conserved site GO:0003723|GO:0045893 AFK25_04640 724545377b7bb45e332ec646165b9e72 281 SUPERFAMILY SSF50151 5 57 1.83E-16 T 11-10-2018 IPR036650 CAT RNA-binding domain superfamily GO:0003723 AFK25_04640 724545377b7bb45e332ec646165b9e72 281 SMART SM01061 5 63 8.7E-27 T 11-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 AFK25_04640 724545377b7bb45e332ec646165b9e72 281 SUPERFAMILY SSF63520 179 276 2.49E-25 T 11-10-2018 IPR036634 PRD domain superfamily GO:0006355 AFK25_04640 724545377b7bb45e332ec646165b9e72 281 Gene3D G3DSA:1.20.58.1950 226 277 5.8E-25 T 11-10-2018 AFK25_04640 724545377b7bb45e332ec646165b9e72 281 Gene3D G3DSA:1.10.1790.10 71 169 4.2E-34 T 11-10-2018 AFK25_04640 724545377b7bb45e332ec646165b9e72 281 Pfam PF03123 CAT RNA binding domain 6 61 3.3E-23 T 11-10-2018 IPR004341 CAT RNA-binding domain GO:0003723 AFK25_06410 d0c4e3fe564db68eb6263c21ce54350b 325 SUPERFAMILY SSF53822 61 325 5.69E-60 T 11-10-2018 IPR028082 Periplasmic binding protein-like I AFK25_06410 d0c4e3fe564db68eb6263c21ce54350b 325 SMART SM00354 1 71 1.2E-26 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_06410 d0c4e3fe564db68eb6263c21ce54350b 325 ProSitePatterns PS00356 LacI-type HTH domain signature. 4 22 - T 11-10-2018 AFK25_06410 d0c4e3fe564db68eb6263c21ce54350b 325 Pfam PF00356 Bacterial regulatory proteins, lacI family 4 48 3.2E-16 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_06410 d0c4e3fe564db68eb6263c21ce54350b 325 SUPERFAMILY SSF47413 1 60 2.57E-16 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFK25_06410 d0c4e3fe564db68eb6263c21ce54350b 325 Gene3D G3DSA:3.40.50.2300 150 325 1.4E-37 T 11-10-2018 AFK25_06410 d0c4e3fe564db68eb6263c21ce54350b 325 Pfam PF00532 Periplasmic binding proteins and sugar binding domain of LacI family 61 322 2.9E-34 T 11-10-2018 IPR001761 Periplasmic binding protein/LacI sugar binding domain AFK25_06410 d0c4e3fe564db68eb6263c21ce54350b 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 13 23 2.8E-5 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_06410 d0c4e3fe564db68eb6263c21ce54350b 325 PRINTS PR00036 LacI bacterial regulatory protein HTH signature 3 13 2.8E-5 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_06410 d0c4e3fe564db68eb6263c21ce54350b 325 Gene3D G3DSA:1.10.260.40 3 58 5.6E-20 T 11-10-2018 AFK25_06410 d0c4e3fe564db68eb6263c21ce54350b 325 Gene3D G3DSA:3.40.50.2300 59 148 1.9E-21 T 11-10-2018 AFK25_02855 6c3bccd935968d39dff26cbda682baf5 394 PIRSF PIRSF037259 2 393 1.5E-89 T 11-10-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 AFK25_02855 6c3bccd935968d39dff26cbda682baf5 394 Pfam PF05975 Bacterial ABC transporter protein EcsB 5 377 5.8E-101 T 11-10-2018 IPR010288 Bacterial ABC transporter EcsB GO:0016021 AFK25_04350 07048fd3fe1ee687ca4c0db803dfeb1e 221 Gene3D G3DSA:3.40.50.10420 37 219 6.9E-39 T 11-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily AFK25_04350 07048fd3fe1ee687ca4c0db803dfeb1e 221 Pfam PF02589 LUD domain 43 218 1.6E-33 T 11-10-2018 IPR003741 LUD domain AFK25_04350 07048fd3fe1ee687ca4c0db803dfeb1e 221 SUPERFAMILY SSF100950 37 218 6.28E-44 T 11-10-2018 IPR037171 NagB/RpiA transferase-like AFK25_04350 07048fd3fe1ee687ca4c0db803dfeb1e 221 Hamap MF_02104 Lactate utilization protein C [lutC]. 1 218 45.326 T 11-10-2018 IPR022823 Lactate utilization protein C AFK25_12745 8b079653a4d7968ecdd4da015c54209c 114 Gene3D G3DSA:1.20.1290.10 1 113 4.2E-28 T 11-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFK25_12745 8b079653a4d7968ecdd4da015c54209c 114 Pfam PF02627 Carboxymuconolactone decarboxylase family 24 103 3.0E-20 T 11-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFK25_12745 8b079653a4d7968ecdd4da015c54209c 114 SUPERFAMILY SSF69118 3 112 4.32E-26 T 11-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AFK25_12745 8b079653a4d7968ecdd4da015c54209c 114 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 39 89 2.6E-10 T 11-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFK25_08585 f7576043ffdb2f4d6cafea9619561cac 257 Pfam PF02675 S-adenosylmethionine decarboxylase 30 161 1.1E-31 T 11-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 AFK25_08585 f7576043ffdb2f4d6cafea9619561cac 257 SUPERFAMILY SSF56276 39 165 1.84E-24 T 11-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 AFK25_08585 f7576043ffdb2f4d6cafea9619561cac 257 PIRSF PIRSF001356 1 255 4.1E-130 T 11-10-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 AFK25_08585 f7576043ffdb2f4d6cafea9619561cac 257 Gene3D G3DSA:3.60.90.10 93 175 2.5E-8 T 11-10-2018 AFK25_08585 f7576043ffdb2f4d6cafea9619561cac 257 TIGRFAM TIGR03331 SAM_DCase_Eco: S-adenosylmethionine decarboxylase proenzyme 1 253 1.5E-135 T 11-10-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 AFK25_08585 f7576043ffdb2f4d6cafea9619561cac 257 Hamap MF_00465 S-adenosylmethionine decarboxylase proenzyme [speD]. 1 257 151.994 T 11-10-2018 IPR009165 S-adenosylmethionine decarboxylase, bacterial GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 AFK25_08390 90017291ae734ba670e92541ddcd4e5d 67 Pfam PF00403 Heavy-metal-associated domain 4 65 1.3E-18 T 11-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AFK25_08390 90017291ae734ba670e92541ddcd4e5d 67 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 3 66 3.1E-22 T 11-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 AFK25_08390 90017291ae734ba670e92541ddcd4e5d 67 PRINTS PR00946 Mercury scavenger protein signature 26 41 8.4E-9 T 11-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 AFK25_08390 90017291ae734ba670e92541ddcd4e5d 67 PRINTS PR00946 Mercury scavenger protein signature 55 67 8.4E-9 T 11-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 AFK25_08390 90017291ae734ba670e92541ddcd4e5d 67 PRINTS PR00946 Mercury scavenger protein signature 10 26 8.4E-9 T 11-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 AFK25_08390 90017291ae734ba670e92541ddcd4e5d 67 PRINTS PR00946 Mercury scavenger protein signature 41 55 8.4E-9 T 11-10-2018 IPR001802 Mercuric transport protein periplasmic component/copper chaperone CopZ GO:0046872 AFK25_08390 90017291ae734ba670e92541ddcd4e5d 67 Gene3D G3DSA:3.30.70.100 1 67 6.1E-25 T 11-10-2018 AFK25_08390 90017291ae734ba670e92541ddcd4e5d 67 SUPERFAMILY SSF55008 1 66 1.07E-21 T 11-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 AFK25_08390 90017291ae734ba670e92541ddcd4e5d 67 ProSitePatterns PS01047 Heavy-metal-associated domain. 7 36 - T 11-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 AFK25_10510 983c29f1bf39e2b5eb2e694534ba9050 179 Gene3D G3DSA:1.20.120.1760 2 176 1.0E-11 T 11-10-2018 AFK25_10510 983c29f1bf39e2b5eb2e694534ba9050 179 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 59 81 - T 11-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFK25_10510 983c29f1bf39e2b5eb2e694534ba9050 179 Pfam PF01066 CDP-alcohol phosphatidyltransferase 18 81 9.7E-14 T 11-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AFK25_10510 983c29f1bf39e2b5eb2e694534ba9050 179 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 23 173 1.3E-38 T 11-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 AFK25_05740 5edae85b60745ebbf6edb83bf94d588e 221 ProSitePatterns PS01061 Flagella transport protein fliP family signature 2. 198 210 - T 11-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFK25_05740 5edae85b60745ebbf6edb83bf94d588e 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 23 42 4.9E-68 T 11-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFK25_05740 5edae85b60745ebbf6edb83bf94d588e 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 150 170 4.9E-68 T 11-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFK25_05740 5edae85b60745ebbf6edb83bf94d588e 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 171 192 4.9E-68 T 11-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFK25_05740 5edae85b60745ebbf6edb83bf94d588e 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 195 220 4.9E-68 T 11-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFK25_05740 5edae85b60745ebbf6edb83bf94d588e 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 62 81 4.9E-68 T 11-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFK25_05740 5edae85b60745ebbf6edb83bf94d588e 221 PRINTS PR01302 Type III secretion system inner membrane P protein family signature 42 62 4.9E-68 T 11-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFK25_05740 5edae85b60745ebbf6edb83bf94d588e 221 ProSitePatterns PS01060 Flagella transport protein fliP family signature 1. 150 165 - T 11-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFK25_05740 5edae85b60745ebbf6edb83bf94d588e 221 Pfam PF00813 FliP family 25 217 5.8E-86 T 11-10-2018 IPR005838 Type III secretion system inner membrane P protein GO:0009306|GO:0016020 AFK25_05740 5edae85b60745ebbf6edb83bf94d588e 221 TIGRFAM TIGR01103 fliP: flagellar biosynthetic protein FliP 25 221 3.2E-94 T 11-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 AFK25_05740 5edae85b60745ebbf6edb83bf94d588e 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 143 155 3.7E-26 T 11-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 AFK25_05740 5edae85b60745ebbf6edb83bf94d588e 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 121 133 3.7E-26 T 11-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 AFK25_05740 5edae85b60745ebbf6edb83bf94d588e 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 21 30 3.7E-26 T 11-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 AFK25_05740 5edae85b60745ebbf6edb83bf94d588e 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 81 93 3.7E-26 T 11-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 AFK25_05740 5edae85b60745ebbf6edb83bf94d588e 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 93 107 3.7E-26 T 11-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 AFK25_05740 5edae85b60745ebbf6edb83bf94d588e 221 PRINTS PR00951 Flagellar biosynthetic protein FliP signature 211 221 3.7E-26 T 11-10-2018 IPR005837 Flagellar transport protein FliP GO:0009306|GO:0016020 AFK25_01370 208d7b6c666a1133a8dc6b84965dcb75 721 Gene3D G3DSA:1.10.486.10 386 551 1.3E-136 T 11-10-2018 AFK25_01370 208d7b6c666a1133a8dc6b84965dcb75 721 Gene3D G3DSA:3.40.50.300 12 277 5.3E-112 T 11-10-2018 AFK25_01370 208d7b6c666a1133a8dc6b84965dcb75 721 SUPERFAMILY SSF52540 9 647 1.95E-191 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_01370 208d7b6c666a1133a8dc6b84965dcb75 721 Gene3D G3DSA:1.10.10.160 116 190 5.3E-112 T 11-10-2018 IPR013986 DExx box DNA helicase domain superfamily AFK25_01370 208d7b6c666a1133a8dc6b84965dcb75 721 Gene3D G3DSA:3.40.50.300 283 638 1.3E-136 T 11-10-2018 AFK25_01370 208d7b6c666a1133a8dc6b84965dcb75 721 TIGRFAM TIGR01073 pcrA: ATP-dependent DNA helicase PcrA 8 718 0.0 T 11-10-2018 IPR005751 ATP-dependent DNA helicase PcrA GO:0004003|GO:0005737|GO:0006268 AFK25_01370 208d7b6c666a1133a8dc6b84965dcb75 721 Pfam PF13361 UvrD-like helicase C-terminal domain 280 618 3.1E-74 T 11-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFK25_01370 208d7b6c666a1133a8dc6b84965dcb75 721 Pfam PF00580 UvrD/REP helicase N-terminal domain 12 275 2.3E-88 T 11-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 AFK25_14555 f99b3e4fd09f466d34ad6aef2c2fcabd 428 TIGRFAM TIGR00184 purA: adenylosuccinate synthase 5 427 3.3E-198 T 11-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFK25_14555 f99b3e4fd09f466d34ad6aef2c2fcabd 428 SMART SM00788 3 422 6.0E-295 T 11-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFK25_14555 f99b3e4fd09f466d34ad6aef2c2fcabd 428 Gene3D G3DSA:1.10.300.10 100 199 1.8E-105 T 11-10-2018 AFK25_14555 f99b3e4fd09f466d34ad6aef2c2fcabd 428 Pfam PF00709 Adenylosuccinate synthetase 4 420 4.3E-186 T 11-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFK25_14555 f99b3e4fd09f466d34ad6aef2c2fcabd 428 ProSitePatterns PS00513 Adenylosuccinate synthetase active site. 131 142 - T 11-10-2018 IPR033128 Adenylosuccinate synthase, active site KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFK25_14555 f99b3e4fd09f466d34ad6aef2c2fcabd 428 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 428 213.699 T 11-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFK25_14555 f99b3e4fd09f466d34ad6aef2c2fcabd 428 Gene3D G3DSA:3.40.440.10 5 252 1.8E-105 T 11-10-2018 AFK25_14555 f99b3e4fd09f466d34ad6aef2c2fcabd 428 SUPERFAMILY SSF52540 1 427 5.31E-177 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_14555 f99b3e4fd09f466d34ad6aef2c2fcabd 428 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 11-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AFK25_14555 f99b3e4fd09f466d34ad6aef2c2fcabd 428 Gene3D G3DSA:3.90.170.10 265 428 1.5E-71 T 11-10-2018 AFK25_11250 8d60e9cf1d1e777566da6058775293ff 202 TIGRFAM TIGR02046 sdhC_b558_fam: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family 6 202 2.3E-54 T 11-10-2018 IPR011138 Succinate dehydrogenase cytochrome b558 subunit AFK25_11250 8d60e9cf1d1e777566da6058775293ff 202 SUPERFAMILY SSF81343 3 201 7.19E-63 T 11-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFK25_11250 8d60e9cf1d1e777566da6058775293ff 202 PIRSF PIRSF000170 1 202 5.1E-103 T 11-10-2018 IPR016002 Succinate dehydrogenase cytochrome b558 subunit, Firmicute AFK25_11250 8d60e9cf1d1e777566da6058775293ff 202 Gene3D G3DSA:1.20.1300.10 1 202 6.9E-48 T 11-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFK25_11250 8d60e9cf1d1e777566da6058775293ff 202 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 91 193 4.9E-14 T 11-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AFK25_11820 3841e989172ffa26352970dc0d1f6b84 563 Hamap MF_00728 Septation ring formation regulator EzrA [ezrA]. 1 562 21.751 T 11-10-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 AFK25_11820 3841e989172ffa26352970dc0d1f6b84 563 Pfam PF06160 Septation ring formation regulator, EzrA 6 557 3.1E-182 T 11-10-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 AFK25_11820 3841e989172ffa26352970dc0d1f6b84 563 SUPERFAMILY SSF58104 106 191 5.75E-5 T 11-10-2018 AFK25_09405 5199d2462ff57f4c453ef434ed726f8d 245 SUPERFAMILY SSF88659 165 243 3.36E-18 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFK25_09405 5199d2462ff57f4c453ef434ed726f8d 245 Gene3D G3DSA:1.10.10.10 168 245 1.1E-12 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_09405 5199d2462ff57f4c453ef434ed726f8d 245 Pfam PF04545 Sigma-70, region 4 192 240 3.4E-16 T 11-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFK25_09405 5199d2462ff57f4c453ef434ed726f8d 245 PIRSF PIRSF000770 4 245 1.4E-37 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_09405 5199d2462ff57f4c453ef434ed726f8d 245 Gene3D G3DSA:1.10.601.10 2 98 9.1E-30 T 11-10-2018 AFK25_09405 5199d2462ff57f4c453ef434ed726f8d 245 TIGRFAM TIGR02980 SigBFG: RNA polymerase sigma-70 factor, sigma-B/F/G subfamily 24 243 1.2E-87 T 11-10-2018 IPR014322 RNA polymerase sigma-B/F/G type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFK25_09405 5199d2462ff57f4c453ef434ed726f8d 245 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 213 239 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_09405 5199d2462ff57f4c453ef434ed726f8d 245 Pfam PF04539 Sigma-70 region 3 111 179 7.3E-13 T 11-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 AFK25_09405 5199d2462ff57f4c453ef434ed726f8d 245 Pfam PF04542 Sigma-70 region 2 32 99 1.2E-17 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_09405 5199d2462ff57f4c453ef434ed726f8d 245 SUPERFAMILY SSF88659 103 179 2.31E-17 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFK25_09405 5199d2462ff57f4c453ef434ed726f8d 245 SUPERFAMILY SSF88946 7 99 5.36E-35 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_09405 5199d2462ff57f4c453ef434ed726f8d 245 Gene3D G3DSA:1.10.10.10 99 162 5.2E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_09405 5199d2462ff57f4c453ef434ed726f8d 245 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 55 68 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_09405 5199d2462ff57f4c453ef434ed726f8d 245 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 27 242 4.7E-38 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFK25_09405 5199d2462ff57f4c453ef434ed726f8d 245 TIGRFAM TIGR02885 spore_sigF: RNA polymerase sigma-F factor 16 243 3.0E-112 T 11-10-2018 IPR014236 RNA polymerase sigma-F type GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFK25_09405 5199d2462ff57f4c453ef434ed726f8d 245 PRINTS PR00046 Major sigma-70 factor signature 55 68 3.3E-11 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_09405 5199d2462ff57f4c453ef434ed726f8d 245 PRINTS PR00046 Major sigma-70 factor signature 213 228 3.3E-11 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_09405 5199d2462ff57f4c453ef434ed726f8d 245 PRINTS PR00046 Major sigma-70 factor signature 228 239 3.3E-11 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_09405 5199d2462ff57f4c453ef434ed726f8d 245 PRINTS PR00046 Major sigma-70 factor signature 196 208 3.3E-11 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_09405 5199d2462ff57f4c453ef434ed726f8d 245 PRINTS PR00046 Major sigma-70 factor signature 79 87 3.3E-11 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_14530 05ca439d947e36b5290f084566214ae3 442 Pfam PF07435 YycH protein 4 433 6.6E-98 T 11-10-2018 IPR009996 Regulatory protein YycH AFK25_14530 05ca439d947e36b5290f084566214ae3 442 Gene3D G3DSA:3.30.310.160 223 363 1.4E-51 T 11-10-2018 AFK25_14530 05ca439d947e36b5290f084566214ae3 442 Gene3D G3DSA:3.10.450.310 201 401 1.4E-51 T 11-10-2018 AFK25_03305 12dae81d1f8d61f25b968c359f2fed56 173 Pfam PF02572 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP 1 172 9.5E-62 T 11-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 AFK25_03305 12dae81d1f8d61f25b968c359f2fed56 173 TIGRFAM TIGR00708 cobA: cob(I)yrinic acid a,c-diamide adenosyltransferase 1 172 2.3E-54 T 11-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 AFK25_03305 12dae81d1f8d61f25b968c359f2fed56 173 SUPERFAMILY SSF52540 1 172 5.31E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_03305 12dae81d1f8d61f25b968c359f2fed56 173 PIRSF PIRSF015617 1 173 9.5E-61 T 11-10-2018 IPR003724 ATP:cob(I)alamin adenosyltransferase CobA/CobO/ButR GO:0005524|GO:0008817|GO:0009236 KEGG: 00860+2.5.1.17 AFK25_03305 12dae81d1f8d61f25b968c359f2fed56 173 Gene3D G3DSA:3.40.50.300 1 173 3.8E-65 T 11-10-2018 AFK25_00185 6e86ec6eb791ea36ee10405aacb87d0b 332 Gene3D G3DSA:3.40.50.300 6 167 4.3E-56 T 11-10-2018 AFK25_00185 6e86ec6eb791ea36ee10405aacb87d0b 332 Pfam PF13177 DNA polymerase III, delta subunit 10 168 2.4E-59 T 11-10-2018 AFK25_00185 6e86ec6eb791ea36ee10405aacb87d0b 332 SUPERFAMILY SSF52540 10 195 1.3E-46 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_00185 6e86ec6eb791ea36ee10405aacb87d0b 332 TIGRFAM TIGR00678 holB: DNA polymerase III, delta' subunit 15 197 9.7E-67 T 11-10-2018 IPR004622 DNA polymerase III, delta prime subunit GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_09860 7567372d123d147c3331e42456deb85c 164 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 118 135 - T 11-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AFK25_09860 7567372d123d147c3331e42456deb85c 164 Gene3D G3DSA:2.40.50.100 84 161 2.6E-31 T 11-10-2018 AFK25_09860 7567372d123d147c3331e42456deb85c 164 SUPERFAMILY SSF51230 85 161 6.28E-25 T 11-10-2018 IPR011053 Single hybrid motif AFK25_09860 7567372d123d147c3331e42456deb85c 164 TIGRFAM TIGR00531 BCCP: acetyl-CoA carboxylase, biotin carboxyl carrier protein 2 162 4.2E-53 T 11-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 AFK25_09860 7567372d123d147c3331e42456deb85c 164 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 123 136 9.5E-18 T 11-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 AFK25_09860 7567372d123d147c3331e42456deb85c 164 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 91 104 9.5E-18 T 11-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 AFK25_09860 7567372d123d147c3331e42456deb85c 164 PRINTS PR01071 Acetyl-CoA biotin carboxyl carrier protein signature 108 122 9.5E-18 T 11-10-2018 IPR001249 Acetyl-CoA biotin carboxyl carrier GO:0003989|GO:0006633|GO:0009317 AFK25_09860 7567372d123d147c3331e42456deb85c 164 Pfam PF00364 Biotin-requiring enzyme 87 159 4.3E-24 T 11-10-2018 IPR000089 Biotin/lipoyl attachment AFK25_00225 a5a1ddd0b56e3d36107b3a71cc838548 397 Pfam PF06725 3D domain 336 397 5.0E-18 T 11-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 AFK25_00225 a5a1ddd0b56e3d36107b3a71cc838548 397 SMART SM01208 210 288 3.6E-25 T 11-10-2018 IPR011098 G5 domain AFK25_00225 a5a1ddd0b56e3d36107b3a71cc838548 397 Gene3D G3DSA:2.20.230.10 164 287 3.7E-17 T 11-10-2018 AFK25_00225 a5a1ddd0b56e3d36107b3a71cc838548 397 Pfam PF03990 Domain of unknown function (DUF348) 157 197 3.9E-13 T 11-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 AFK25_00225 a5a1ddd0b56e3d36107b3a71cc838548 397 Pfam PF03990 Domain of unknown function (DUF348) 101 140 5.2E-10 T 11-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 AFK25_00225 a5a1ddd0b56e3d36107b3a71cc838548 397 Pfam PF03990 Domain of unknown function (DUF348) 43 82 1.2E-12 T 11-10-2018 IPR007137 Resuscitation-promoting factor, domain of unknown function DUF348 AFK25_00225 a5a1ddd0b56e3d36107b3a71cc838548 397 SUPERFAMILY SSF50685 337 378 4.53E-6 T 11-10-2018 IPR036908 RlpA-like domain superfamily AFK25_00225 a5a1ddd0b56e3d36107b3a71cc838548 397 Pfam PF07501 G5 domain 215 287 1.6E-19 T 11-10-2018 IPR011098 G5 domain AFK25_14625 8f5a8857c13eac015e66f018ab24bd2a 253 SUPERFAMILY SSF52540 2 251 3.8E-71 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_14625 8f5a8857c13eac015e66f018ab24bd2a 253 Pfam PF13614 AAA domain 2 178 5.8E-72 T 11-10-2018 IPR025669 AAA domain AFK25_14625 8f5a8857c13eac015e66f018ab24bd2a 253 Gene3D G3DSA:3.40.50.300 1 252 4.9E-83 T 11-10-2018 AFK25_14625 8f5a8857c13eac015e66f018ab24bd2a 253 PIRSF PIRSF009320 90 252 9.5E-9 T 11-10-2018 AFK25_14625 8f5a8857c13eac015e66f018ab24bd2a 253 PIRSF PIRSF009320 2 81 6.1E-15 T 11-10-2018 AFK25_12300 fb8d4c5a25cc0b2f111b458f0f05f216 484 SUPERFAMILY SSF53756 3 476 3.14E-136 T 11-10-2018 AFK25_12300 fb8d4c5a25cc0b2f111b458f0f05f216 484 Gene3D G3DSA:3.40.50.2000 3 472 3.2E-188 T 11-10-2018 AFK25_12300 fb8d4c5a25cc0b2f111b458f0f05f216 484 Hamap MF_00484 Glycogen synthase [glgA]. 1 474 47.997 T 11-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 AFK25_12300 fb8d4c5a25cc0b2f111b458f0f05f216 484 Pfam PF08323 Starch synthase catalytic domain 2 236 5.7E-88 T 11-10-2018 IPR013534 Starch synthase, catalytic domain KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 AFK25_12300 fb8d4c5a25cc0b2f111b458f0f05f216 484 Pfam PF00534 Glycosyl transferases group 1 283 435 3.6E-16 T 11-10-2018 IPR001296 Glycosyl transferase, family 1 AFK25_12300 fb8d4c5a25cc0b2f111b458f0f05f216 484 TIGRFAM TIGR02095 glgA: glycogen/starch synthase, ADP-glucose type 2 474 2.4E-180 T 11-10-2018 IPR011835 Bacterial/plant glycogen synthase GO:0004373 KEGG: 00500+2.4.1.21|MetaCyc: PWY-622 AFK25_12300 fb8d4c5a25cc0b2f111b458f0f05f216 484 Gene3D G3DSA:3.40.50.2000 250 458 3.2E-188 T 11-10-2018 AFK25_10295 035ffb5f89a87e03384d31e25a122a90 200 PIRSF PIRSF026546 1 198 3.5E-98 T 11-10-2018 IPR016842 Protein of unknown function UCP026546, HtH-CBS AFK25_10295 035ffb5f89a87e03384d31e25a122a90 200 SUPERFAMILY SSF54631 58 192 3.54E-23 T 11-10-2018 AFK25_10295 035ffb5f89a87e03384d31e25a122a90 200 SUPERFAMILY SSF46785 1 68 3.25E-11 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_10295 035ffb5f89a87e03384d31e25a122a90 200 Pfam PF00571 CBS domain 135 191 9.8E-5 T 11-10-2018 IPR000644 CBS domain AFK25_10295 035ffb5f89a87e03384d31e25a122a90 200 Pfam PF00571 CBS domain 74 121 1.5E-6 T 11-10-2018 IPR000644 CBS domain AFK25_10295 035ffb5f89a87e03384d31e25a122a90 200 Pfam PF08279 HTH domain 1 49 2.7E-11 T 11-10-2018 IPR013196 Helix-turn-helix, type 11 AFK25_10295 035ffb5f89a87e03384d31e25a122a90 200 Gene3D G3DSA:3.10.580.10 51 200 9.5E-59 T 11-10-2018 AFK25_10295 035ffb5f89a87e03384d31e25a122a90 200 Gene3D G3DSA:1.10.10.10 1 50 5.8E-7 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_10295 035ffb5f89a87e03384d31e25a122a90 200 SMART SM00116 74 122 0.12 T 11-10-2018 IPR000644 CBS domain AFK25_10295 035ffb5f89a87e03384d31e25a122a90 200 SMART SM00116 141 192 0.36 T 11-10-2018 IPR000644 CBS domain AFK25_10115 4319aa82b3bb558e269d9c624d41cf9b 190 Pfam PF01812 5-formyltetrahydrofolate cyclo-ligase family 3 179 7.0E-45 T 11-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase AFK25_10115 4319aa82b3bb558e269d9c624d41cf9b 190 Gene3D G3DSA:3.40.50.10420 1 189 7.2E-61 T 11-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily AFK25_10115 4319aa82b3bb558e269d9c624d41cf9b 190 TIGRFAM TIGR02727 MTHFS_bact: 5-formyltetrahydrofolate cyclo-ligase 3 179 7.5E-52 T 11-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase AFK25_10115 4319aa82b3bb558e269d9c624d41cf9b 190 SUPERFAMILY SSF100950 1 187 1.81E-50 T 11-10-2018 IPR037171 NagB/RpiA transferase-like AFK25_10115 4319aa82b3bb558e269d9c624d41cf9b 190 PIRSF PIRSF006806 1 183 1.1E-51 T 11-10-2018 IPR002698 5-formyltetrahydrofolate cyclo-ligase AFK25_11115 77e6a8338c17fdce5b8c7152334b9310 271 Pfam PF01578 Cytochrome C assembly protein 66 267 6.7E-28 T 11-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 AFK25_08505 af4b84926a483493d1c406289e31ffb5 329 Pfam PF14281 PD-(D/E)XK nuclease superfamily 5 126 2.3E-9 T 11-10-2018 IPR029470 PD-(D/E)XK nuclease superfamily 4 AFK25_03350 988aee05f35af5bcb64df96b1323c6ea 251 Gene3D G3DSA:3.40.50.1820 2 251 1.1E-54 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold AFK25_03350 988aee05f35af5bcb64df96b1323c6ea 251 SUPERFAMILY SSF53474 15 251 8.99E-38 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold AFK25_03350 988aee05f35af5bcb64df96b1323c6ea 251 Pfam PF00326 Prolyl oligopeptidase family 93 247 1.8E-12 T 11-10-2018 IPR001375 Peptidase S9, prolyl oligopeptidase, catalytic domain GO:0006508|GO:0008236 AFK25_11625 b61ad268a85181cb57bc512f57f76a4f 372 Pfam PF01594 AI-2E family transporter 14 353 2.6E-65 T 11-10-2018 IPR002549 Transmembrane protein TqsA-like AFK25_11625 b61ad268a85181cb57bc512f57f76a4f 372 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 11 359 3.2E-114 T 11-10-2018 IPR014227 Putative transport protein YtvI-like AFK25_10725 28a3b19527428068083f2796f7c5a636 425 Gene3D G3DSA:1.10.3710.10 333 425 3.1E-27 T 11-10-2018 AFK25_10725 28a3b19527428068083f2796f7c5a636 425 Pfam PF16193 AAA C-terminal domain 176 254 4.6E-22 T 11-10-2018 IPR032423 AAA C-terminal domain AFK25_10725 28a3b19527428068083f2796f7c5a636 425 SUPERFAMILY SSF48019 240 423 6.8E-70 T 11-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 AFK25_10725 28a3b19527428068083f2796f7c5a636 425 SUPERFAMILY SSF52540 5 222 7.02E-45 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_10725 28a3b19527428068083f2796f7c5a636 425 Gene3D G3DSA:3.40.50.300 2 148 5.1E-41 T 11-10-2018 AFK25_10725 28a3b19527428068083f2796f7c5a636 425 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 44 146 5.4E-17 T 11-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AFK25_10725 28a3b19527428068083f2796f7c5a636 425 SMART SM00382 40 154 1.7E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_10725 28a3b19527428068083f2796f7c5a636 425 Gene3D G3DSA:1.10.8.60 153 225 1.3E-17 T 11-10-2018 AFK25_10725 28a3b19527428068083f2796f7c5a636 425 Gene3D G3DSA:1.20.272.10 230 332 2.7E-39 T 11-10-2018 AFK25_10725 28a3b19527428068083f2796f7c5a636 425 Pfam PF12002 MgsA AAA+ ATPase C terminal 255 419 2.6E-65 T 11-10-2018 IPR021886 MgsA AAA+ ATPase C-terminal AFK25_09540 c39d51586012dae1735efb44afc54541 189 Hamap MF_00316 Molybdenum cofactor guanylyltransferase [mobA]. 1 187 23.642 T 11-10-2018 IPR013482 Molybdenum cofactor guanylyltransferase GO:0003824|GO:0006777 KEGG: 00790+2.7.7.77|MetaCyc: PWY-5964|MetaCyc: PWY-7639 AFK25_09540 c39d51586012dae1735efb44afc54541 189 SUPERFAMILY SSF53448 1 184 5.85E-33 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_09540 c39d51586012dae1735efb44afc54541 189 Gene3D G3DSA:3.90.550.10 1 188 1.3E-49 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_09540 c39d51586012dae1735efb44afc54541 189 Pfam PF12804 MobA-like NTP transferase domain 5 149 4.5E-33 T 11-10-2018 IPR025877 MobA-like NTP transferase AFK25_03110 8639fc2e3033643b95a895e5901d32bb 396 SUPERFAMILY SSF53383 3 395 2.34E-127 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_03110 8639fc2e3033643b95a895e5901d32bb 396 Hamap MF_01689 Ornithine aminotransferase [rocD]. 3 395 67.67 T 11-10-2018 IPR034757 Ornithine aminotransferase, bacterial type GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922 AFK25_03110 8639fc2e3033643b95a895e5901d32bb 396 Gene3D G3DSA:3.40.640.10 57 305 8.9E-153 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_03110 8639fc2e3033643b95a895e5901d32bb 396 TIGRFAM TIGR01885 Orn_aminotrans: ornithine--oxo-acid transaminase 4 394 4.0E-166 T 11-10-2018 IPR010164 Ornithine aminotransferase GO:0004587 KEGG: 00330+2.6.1.13|MetaCyc: PWY-3341|MetaCyc: PWY-4981|MetaCyc: PWY-6344|MetaCyc: PWY-6922|Reactome: R-HSA-70614 AFK25_03110 8639fc2e3033643b95a895e5901d32bb 396 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 222 259 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFK25_03110 8639fc2e3033643b95a895e5901d32bb 396 Gene3D G3DSA:3.90.1150.10 22 384 8.9E-153 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_03110 8639fc2e3033643b95a895e5901d32bb 396 PIRSF PIRSF000521 2 159 2.1E-8 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFK25_03110 8639fc2e3033643b95a895e5901d32bb 396 PIRSF PIRSF000521 172 396 2.8E-34 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFK25_03110 8639fc2e3033643b95a895e5901d32bb 396 Pfam PF00202 Aminotransferase class-III 14 393 2.3E-132 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFK25_09960 e3e6da86c5d03a6ad0b0a11b00d7a5f2 278 Hamap MF_02118 Octanoyltransferase LipM [lipM]. 3 278 68.46 T 11-10-2018 IPR024898 Octanoyltransferase LipM GO:0009107|GO:0009249|GO:0016415 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 AFK25_09960 e3e6da86c5d03a6ad0b0a11b00d7a5f2 278 Gene3D G3DSA:3.30.930.10 5 278 2.7E-71 T 11-10-2018 AFK25_09960 e3e6da86c5d03a6ad0b0a11b00d7a5f2 278 Pfam PF03099 Biotin/lipoate A/B protein ligase family 52 189 3.5E-27 T 11-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 AFK25_09960 e3e6da86c5d03a6ad0b0a11b00d7a5f2 278 SUPERFAMILY SSF55681 5 278 8.29E-72 T 11-10-2018 AFK25_06625 eb0228a7a24773a654af5cf08e643c4b 372 Gene3D G3DSA:3.30.9.10 87 310 3.2E-75 T 11-10-2018 AFK25_06625 eb0228a7a24773a654af5cf08e643c4b 372 Pfam PF01266 FAD dependent oxidoreductase 4 349 4.8E-51 T 11-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFK25_06625 eb0228a7a24773a654af5cf08e643c4b 372 SUPERFAMILY SSF51905 3 366 2.2E-37 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_06625 eb0228a7a24773a654af5cf08e643c4b 372 SUPERFAMILY SSF54373 220 309 2.09E-15 T 11-10-2018 AFK25_06625 eb0228a7a24773a654af5cf08e643c4b 372 Gene3D G3DSA:3.50.50.60 5 351 3.2E-75 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_02805 98efb1e18da05c594f058aafc230a1fa 358 Gene3D G3DSA:3.40.640.10 17 254 1.1E-86 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_02805 98efb1e18da05c594f058aafc230a1fa 358 Gene3D G3DSA:3.90.1150.10 255 357 2.2E-41 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_02805 98efb1e18da05c594f058aafc230a1fa 358 Hamap MF_00160 Phosphoserine aminotransferase [serC]. 2 357 48.923 T 11-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 AFK25_02805 98efb1e18da05c594f058aafc230a1fa 358 SUPERFAMILY SSF53383 1 355 6.61E-114 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_02805 98efb1e18da05c594f058aafc230a1fa 358 TIGRFAM TIGR01364 serC_1: phosphoserine transaminase 5 355 8.6E-156 T 11-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 AFK25_02805 98efb1e18da05c594f058aafc230a1fa 358 Pfam PF00266 Aminotransferase class-V 5 346 1.7E-51 T 11-10-2018 IPR000192 Aminotransferase class V domain AFK25_02805 98efb1e18da05c594f058aafc230a1fa 358 PIRSF PIRSF000525 1 357 4.6E-151 T 11-10-2018 IPR022278 Phosphoserine aminotransferase GO:0004648|GO:0006564 KEGG: 00260+2.6.1.52|KEGG: 00680+2.6.1.52|KEGG: 00750+2.6.1.52|Reactome: R-HSA-977347 AFK25_01260 7436c56efedd7ff51e06d5b0a25f4fdc 441 PIRSF PIRSF005353 1 441 2.8E-180 T 11-10-2018 IPR026033 Purine permease PbuG-like AFK25_01260 7436c56efedd7ff51e06d5b0a25f4fdc 441 Pfam PF00860 Permease family 17 402 1.0E-49 T 11-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 AFK25_02790 ae00d8a31755f15eb602c8e1011bb906 499 Gene3D G3DSA:3.80.30.20 136 495 7.6E-69 T 11-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe AFK25_02790 ae00d8a31755f15eb602c8e1011bb906 499 TIGRFAM TIGR03994 rSAM_HemZ: coproporphyrinogen dehydrogenase HemZ 93 494 1.6E-150 T 11-10-2018 IPR023995 Oxygen-independent coproporphyrinogen-III oxidase-like protein HemZ AFK25_02790 ae00d8a31755f15eb602c8e1011bb906 499 SMART SM00729 175 399 1.6E-48 T 11-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AFK25_02790 ae00d8a31755f15eb602c8e1011bb906 499 SUPERFAMILY SSF102114 167 486 2.75E-70 T 11-10-2018 AFK25_02790 ae00d8a31755f15eb602c8e1011bb906 499 Pfam PF04055 Radical SAM superfamily 183 355 3.7E-18 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFK25_04420 371b53b57d7b910ae9e88cf35e88a93e 283 SUPERFAMILY SSF103481 186 281 6.15E-16 T 11-10-2018 AFK25_04420 371b53b57d7b910ae9e88cf35e88a93e 283 Pfam PF00892 EamA-like transporter family 149 280 3.8E-28 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFK25_04420 371b53b57d7b910ae9e88cf35e88a93e 283 Pfam PF00892 EamA-like transporter family 4 136 1.9E-28 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFK25_04420 371b53b57d7b910ae9e88cf35e88a93e 283 SUPERFAMILY SSF103481 37 140 5.62E-17 T 11-10-2018 AFK25_01635 96c13609e982ad896dfdbf2c1940edc0 151 Gene3D G3DSA:1.10.1740.10 1 69 1.3E-17 T 11-10-2018 AFK25_01635 96c13609e982ad896dfdbf2c1940edc0 151 Pfam PF04542 Sigma-70 region 2 3 62 1.6E-14 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_01635 96c13609e982ad896dfdbf2c1940edc0 151 SUPERFAMILY SSF88946 2 85 7.85E-18 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_01635 96c13609e982ad896dfdbf2c1940edc0 151 Pfam PF08281 Sigma-70, region 4 89 140 4.7E-15 T 11-10-2018 IPR013249 RNA polymerase sigma factor 70, region 4 type 2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFK25_01635 96c13609e982ad896dfdbf2c1940edc0 151 SUPERFAMILY SSF88659 91 145 1.03E-15 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFK25_01635 96c13609e982ad896dfdbf2c1940edc0 151 Gene3D G3DSA:1.10.10.10 84 146 3.8E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_01635 96c13609e982ad896dfdbf2c1940edc0 151 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 3 144 1.4E-24 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFK25_03760 198f8850cd5f1ba7fb495f591e4d24cd 367 Gene3D G3DSA:3.40.640.10 3 245 6.8E-88 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_03760 198f8850cd5f1ba7fb495f591e4d24cd 367 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 5 362 2.8E-134 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFK25_03760 198f8850cd5f1ba7fb495f591e4d24cd 367 ProSitePatterns PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. 188 202 - T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFK25_03760 198f8850cd5f1ba7fb495f591e4d24cd 367 Gene3D G3DSA:3.90.1150.10 246 278 3.2E-7 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_03760 198f8850cd5f1ba7fb495f591e4d24cd 367 Gene3D G3DSA:3.90.1150.10 279 362 5.3E-25 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_03760 198f8850cd5f1ba7fb495f591e4d24cd 367 SUPERFAMILY SSF53383 15 363 1.46E-105 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_03760 198f8850cd5f1ba7fb495f591e4d24cd 367 PIRSF PIRSF001434 1 365 7.6E-124 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFK25_04250 14d1d3d9193bdd2bf9f167664850ce41 167 Gene3D G3DSA:1.20.1260.10 1 167 5.7E-51 T 11-10-2018 IPR012347 Ferritin-like AFK25_04250 14d1d3d9193bdd2bf9f167664850ce41 167 Pfam PF00210 Ferritin-like domain 8 144 7.0E-43 T 11-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 AFK25_04250 14d1d3d9193bdd2bf9f167664850ce41 167 SUPERFAMILY SSF47240 1 161 1.02E-58 T 11-10-2018 IPR009078 Ferritin-like superfamily AFK25_09520 363a744ed2d449b33efd08e4878cfde2 77 Pfam PF02597 ThiS family 4 77 6.1E-17 T 11-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 AFK25_09520 363a744ed2d449b33efd08e4878cfde2 77 Gene3D G3DSA:3.10.20.30 1 77 1.3E-21 T 11-10-2018 IPR012675 Beta-grasp domain superfamily AFK25_09520 363a744ed2d449b33efd08e4878cfde2 77 TIGRFAM TIGR01682 moaD: molybdopterin converting factor, subunit 1 2 77 2.8E-21 T 11-10-2018 AFK25_09520 363a744ed2d449b33efd08e4878cfde2 77 SUPERFAMILY SSF54285 1 77 2.06E-17 T 11-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AFK25_13880 85953ba4ff90aeaa413d0ff2d2522016 378 TIGRFAM TIGR00236 wecB: UDP-N-acetylglucosamine 2-epimerase 5 366 1.2E-166 T 11-10-2018 IPR029767 UDP-N-acetylglucosamine 2-epimerase WecB-like GO:0008761 AFK25_13880 85953ba4ff90aeaa413d0ff2d2522016 378 SUPERFAMILY SSF53756 3 368 1.12E-138 T 11-10-2018 AFK25_13880 85953ba4ff90aeaa413d0ff2d2522016 378 Pfam PF02350 UDP-N-acetylglucosamine 2-epimerase 25 363 1.7E-120 T 11-10-2018 IPR003331 UDP-N-acetylglucosamine 2-epimerase domain Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFK25_13880 85953ba4ff90aeaa413d0ff2d2522016 378 Gene3D G3DSA:3.40.50.2000 190 350 1.1E-154 T 11-10-2018 AFK25_13880 85953ba4ff90aeaa413d0ff2d2522016 378 Gene3D G3DSA:3.40.50.2000 6 361 1.1E-154 T 11-10-2018 AFK25_10150 2fa1cee34a61e4f606ed30f4ea5723fa 293 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 94 287 3.1E-24 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_10150 2fa1cee34a61e4f606ed30f4ea5723fa 293 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 22 290 3.0E-86 T 11-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 AFK25_10150 2fa1cee34a61e4f606ed30f4ea5723fa 293 Gene3D G3DSA:1.10.3720.10 69 292 2.7E-36 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_10150 2fa1cee34a61e4f606ed30f4ea5723fa 293 SUPERFAMILY SSF161098 29 278 5.36E-42 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_09295 c8dc776547495126132c5a216195c26e 409 Gene3D G3DSA:3.30.1490.20 135 184 1.0E-6 T 11-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AFK25_09295 c8dc776547495126132c5a216195c26e 409 Gene3D G3DSA:3.40.50.20 9 125 2.6E-6 T 11-10-2018 AFK25_09295 c8dc776547495126132c5a216195c26e 409 Pfam PF13535 ATP-grasp domain 147 294 1.1E-32 T 11-10-2018 AFK25_09295 c8dc776547495126132c5a216195c26e 409 SUPERFAMILY SSF56059 126 315 8.49E-29 T 11-10-2018 AFK25_09295 c8dc776547495126132c5a216195c26e 409 Gene3D G3DSA:3.30.470.20 201 406 2.3E-44 T 11-10-2018 AFK25_04485 25766a7560a68b6f950c9c25d4b9117a 124 Pfam PF13115 YtkA-like 26 107 1.6E-14 T 11-10-2018 IPR032693 YtkA-like domain AFK25_12585 12969b0eece75a79659b6afaab9585b8 227 Pfam PF09986 Uncharacterized protein conserved in bacteria (DUF2225) 4 219 1.3E-62 T 11-10-2018 IPR018708 Protein of unknown function DUF2225 AFK25_12585 12969b0eece75a79659b6afaab9585b8 227 Gene3D G3DSA:1.25.40.10 63 225 1.9E-9 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_12585 12969b0eece75a79659b6afaab9585b8 227 SUPERFAMILY SSF48452 85 203 9.76E-8 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_06390 042c72683a09516a84ef286b7878f2ba 372 Pfam PF01385 Probable transposase 158 263 5.9E-16 T 11-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 AFK25_06390 042c72683a09516a84ef286b7878f2ba 372 Pfam PF07282 Putative transposase DNA-binding domain 290 359 3.1E-19 T 11-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFK25_06390 042c72683a09516a84ef286b7878f2ba 372 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 238 317 2.1E-17 T 11-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFK25_03145 56766bdb1e3ef3cba2da4b0995d3510f 283 Pfam PF00494 Squalene/phytoene synthase 16 265 8.7E-73 T 11-10-2018 AFK25_03145 56766bdb1e3ef3cba2da4b0995d3510f 283 ProSitePatterns PS01044 Squalene and phytoene synthases signature 1. 123 138 - T 11-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AFK25_03145 56766bdb1e3ef3cba2da4b0995d3510f 283 Gene3D G3DSA:1.10.600.10 1 275 4.9E-99 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFK25_03145 56766bdb1e3ef3cba2da4b0995d3510f 283 ProSitePatterns PS01045 Squalene and phytoene synthases signature 2. 154 179 - T 11-10-2018 IPR019845 Squalene/phytoene synthase, conserved site GO:0016765 Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AFK25_03145 56766bdb1e3ef3cba2da4b0995d3510f 283 SUPERFAMILY SSF48576 6 273 2.11E-79 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFK25_13840 93131f7e0123c0b905bdd9d1bd868fd0 286 ProSitePatterns PS00153 ATP synthase gamma subunit signature. 271 284 - T 11-10-2018 IPR023632 ATP synthase, F1 complex, gamma subunit conserved site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13840 93131f7e0123c0b905bdd9d1bd868fd0 286 PRINTS PR00126 ATP synthase gamma subunit signature 74 93 1.2E-40 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13840 93131f7e0123c0b905bdd9d1bd868fd0 286 PRINTS PR00126 ATP synthase gamma subunit signature 167 184 1.2E-40 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13840 93131f7e0123c0b905bdd9d1bd868fd0 286 PRINTS PR00126 ATP synthase gamma subunit signature 263 284 1.2E-40 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13840 93131f7e0123c0b905bdd9d1bd868fd0 286 PRINTS PR00126 ATP synthase gamma subunit signature 232 251 1.2E-40 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13840 93131f7e0123c0b905bdd9d1bd868fd0 286 Gene3D G3DSA:3.40.1380.10 62 204 2.5E-104 T 11-10-2018 AFK25_13840 93131f7e0123c0b905bdd9d1bd868fd0 286 SUPERFAMILY SSF52943 3 285 1.96E-94 T 11-10-2018 IPR035968 ATP synthase, F1 complex, gamma subunit superfamily GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13840 93131f7e0123c0b905bdd9d1bd868fd0 286 TIGRFAM TIGR01146 ATPsyn_F1gamma: ATP synthase F1, gamma subunit 3 285 1.6E-114 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13840 93131f7e0123c0b905bdd9d1bd868fd0 286 Hamap MF_00815 ATP synthase gamma chain [atpG]. 2 285 36.777 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13840 93131f7e0123c0b905bdd9d1bd868fd0 286 Gene3D G3DSA:1.10.287.80 7 281 2.5E-104 T 11-10-2018 AFK25_13840 93131f7e0123c0b905bdd9d1bd868fd0 286 Pfam PF00231 ATP synthase 4 285 5.7E-101 T 11-10-2018 IPR000131 ATP synthase, F1 complex, gamma subunit GO:0015986|GO:0045261|GO:0046933 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_01815 385826bdc4f83a2a464723aca7366161 278 SMART SM00478 118 278 1.5E-26 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFK25_01815 385826bdc4f83a2a464723aca7366161 278 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 114 264 1.7E-22 T 11-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AFK25_01815 385826bdc4f83a2a464723aca7366161 278 SUPERFAMILY SSF48150 99 276 6.91E-45 T 11-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AFK25_01815 385826bdc4f83a2a464723aca7366161 278 Gene3D G3DSA:1.10.1670.40 226 275 4.2E-53 T 11-10-2018 AFK25_01815 385826bdc4f83a2a464723aca7366161 278 Gene3D G3DSA:1.10.340.30 108 225 4.2E-53 T 11-10-2018 AFK25_07805 09a3e466f167b67fe5f2c1158be57953 175 Pfam PF00565 Staphylococcal nuclease homologue 49 155 6.1E-28 T 11-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 AFK25_07805 09a3e466f167b67fe5f2c1158be57953 175 Gene3D G3DSA:2.40.50.90 18 160 2.3E-44 T 11-10-2018 IPR035437 SNase-like, OB-fold superfamily AFK25_07805 09a3e466f167b67fe5f2c1158be57953 175 ProSitePatterns PS01284 Thermonuclease family signature 2. 96 106 - T 11-10-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 AFK25_07805 09a3e466f167b67fe5f2c1158be57953 175 SMART SM00318 24 156 5.8E-39 T 11-10-2018 IPR016071 Staphylococcal nuclease (SNase-like), OB-fold Reactome: R-HSA-6802952 AFK25_07805 09a3e466f167b67fe5f2c1158be57953 175 ProSitePatterns PS01123 Thermonuclease family signature 1. 35 59 - T 11-10-2018 IPR002071 Thermonuclease active site GO:0003676|GO:0004518 Reactome: R-HSA-6802952 AFK25_07805 09a3e466f167b67fe5f2c1158be57953 175 SUPERFAMILY SSF50199 21 161 4.97E-39 T 11-10-2018 AFK25_01505 cf8aa519d030c04bc4cb7c96720dbf82 456 ProSitePatterns PS01230 RNA methyltransferase trmA family signature 1. 384 415 - T 11-10-2018 IPR030390 RNA methyltransferase TrmA, active site AFK25_01505 cf8aa519d030c04bc4cb7c96720dbf82 456 Gene3D G3DSA:3.40.1350.30 130 285 8.6E-129 T 11-10-2018 AFK25_01505 cf8aa519d030c04bc4cb7c96720dbf82 456 SUPERFAMILY SSF53335 69 448 5.91E-93 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_01505 cf8aa519d030c04bc4cb7c96720dbf82 456 SUPERFAMILY SSF50249 2 62 2.34E-16 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_01505 cf8aa519d030c04bc4cb7c96720dbf82 456 Gene3D G3DSA:3.40.50.150 83 448 8.6E-129 T 11-10-2018 AFK25_01505 cf8aa519d030c04bc4cb7c96720dbf82 456 Pfam PF01938 TRAM domain 8 61 2.3E-13 T 11-10-2018 IPR002792 TRAM domain AFK25_01505 cf8aa519d030c04bc4cb7c96720dbf82 456 TIGRFAM TIGR00479 rumA: 23S rRNA (uracil-5-)-methyltransferase RumA 18 446 1.3E-189 T 11-10-2018 AFK25_01505 cf8aa519d030c04bc4cb7c96720dbf82 456 Gene3D G3DSA:2.40.50.140 2 81 5.2E-21 T 11-10-2018 AFK25_01505 cf8aa519d030c04bc4cb7c96720dbf82 456 Pfam PF05958 tRNA (Uracil-5-)-methyltransferase 228 447 7.8E-23 T 11-10-2018 IPR010280 (Uracil-5)-methyltransferase family GO:0006396|GO:0008173 AFK25_01505 cf8aa519d030c04bc4cb7c96720dbf82 456 ProSitePatterns PS01231 RNA methyltransferase trmA family signature 2. 436 446 - T 11-10-2018 IPR030391 RNA methyltransferase TrmA, conserved site AFK25_14640 d8e90d66cd2abc0f2d6fa5ff8a22df0c 629 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 10 29 7.8E-5 T 11-10-2018 AFK25_14640 d8e90d66cd2abc0f2d6fa5ff8a22df0c 629 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 149 167 7.8E-5 T 11-10-2018 AFK25_14640 d8e90d66cd2abc0f2d6fa5ff8a22df0c 629 Pfam PF13932 GidA associated domain 401 615 4.0E-82 T 11-10-2018 IPR026904 GidA associated domain 3 Reactome: R-HSA-6787450 AFK25_14640 d8e90d66cd2abc0f2d6fa5ff8a22df0c 629 SMART SM01228 545 616 7.8E-45 T 11-10-2018 AFK25_14640 d8e90d66cd2abc0f2d6fa5ff8a22df0c 629 Hamap MF_00129 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [mnmG]. 6 623 42.902 T 11-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 AFK25_14640 d8e90d66cd2abc0f2d6fa5ff8a22df0c 629 Gene3D G3DSA:1.10.10.1800 459 549 1.6E-26 T 11-10-2018 AFK25_14640 d8e90d66cd2abc0f2d6fa5ff8a22df0c 629 SUPERFAMILY SSF51905 7 260 2.5E-48 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_14640 d8e90d66cd2abc0f2d6fa5ff8a22df0c 629 TIGRFAM TIGR00136 gidA: tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA 8 620 1.0E-297 T 11-10-2018 IPR004416 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG GO:0002098 Reactome: R-HSA-6787450 AFK25_14640 d8e90d66cd2abc0f2d6fa5ff8a22df0c 629 Gene3D G3DSA:3.50.50.60 1 226 1.6E-87 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_14640 d8e90d66cd2abc0f2d6fa5ff8a22df0c 629 Gene3D G3DSA:3.50.50.60 296 458 4.2E-56 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_14640 d8e90d66cd2abc0f2d6fa5ff8a22df0c 629 Pfam PF01134 Glucose inhibited division protein A 9 399 1.6E-172 T 11-10-2018 IPR002218 tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related GO:0008033|GO:0050660 Reactome: R-HSA-6787450 AFK25_14640 d8e90d66cd2abc0f2d6fa5ff8a22df0c 629 ProSitePatterns PS01281 Glucose inhibited division protein A family signature 2. 368 391 - T 11-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 AFK25_14640 d8e90d66cd2abc0f2d6fa5ff8a22df0c 629 ProSitePatterns PS01280 Glucose inhibited division protein A family signature 1. 273 287 - T 11-10-2018 IPR020595 MnmG-related, conserved site Reactome: R-HSA-6787450 AFK25_14640 d8e90d66cd2abc0f2d6fa5ff8a22df0c 629 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 9 31 1.4E-6 T 11-10-2018 AFK25_14640 d8e90d66cd2abc0f2d6fa5ff8a22df0c 629 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 152 161 1.4E-6 T 11-10-2018 AFK25_14640 d8e90d66cd2abc0f2d6fa5ff8a22df0c 629 Gene3D G3DSA:1.10.150.570 568 620 1.7E-25 T 11-10-2018 AFK25_06065 8d296498460ef27679ecba3b18b3cc14 148 SUPERFAMILY SSF46785 16 137 3.69E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_06065 8d296498460ef27679ecba3b18b3cc14 148 Gene3D G3DSA:1.10.10.10 1 142 2.4E-24 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_06065 8d296498460ef27679ecba3b18b3cc14 148 Pfam PF01047 MarR family 30 87 7.9E-10 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_06065 8d296498460ef27679ecba3b18b3cc14 148 SMART SM00347 23 123 2.0E-7 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_06065 8d296498460ef27679ecba3b18b3cc14 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 64 79 6.5E-8 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_06065 8d296498460ef27679ecba3b18b3cc14 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 83 99 6.5E-8 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_06065 8d296498460ef27679ecba3b18b3cc14 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 47 63 6.5E-8 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_06065 8d296498460ef27679ecba3b18b3cc14 148 PRINTS PR00598 Bacterial regulatory protein MarR family signature 113 133 6.5E-8 T 11-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AFK25_10710 4e71b65579c27994335a06ab2a481f9c 371 Pfam PF03054 tRNA methyl transferase 9 357 2.8E-150 T 11-10-2018 AFK25_10710 4e71b65579c27994335a06ab2a481f9c 371 Hamap MF_00144 tRNA-specific 2-thiouridylase MnmA [mnmA]. 8 358 41.33 T 11-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 AFK25_10710 4e71b65579c27994335a06ab2a481f9c 371 Gene3D G3DSA:2.40.30.10 279 370 6.4E-31 T 11-10-2018 AFK25_10710 4e71b65579c27994335a06ab2a481f9c 371 Gene3D G3DSA:3.40.50.620 2 213 6.7E-99 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_10710 4e71b65579c27994335a06ab2a481f9c 371 SUPERFAMILY SSF52402 8 244 1.41E-59 T 11-10-2018 AFK25_10710 4e71b65579c27994335a06ab2a481f9c 371 TIGRFAM TIGR00420 trmU: tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase 9 357 1.1E-141 T 11-10-2018 IPR004506 tRNA-specific 2-thiouridylase GO:0008033|GO:0016740 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 AFK25_10710 4e71b65579c27994335a06ab2a481f9c 371 Gene3D G3DSA:2.30.30.280 214 277 2.1E-25 T 11-10-2018 IPR023382 Adenine nucleotide alpha hydrolase-like domains GO:0016783 MetaCyc: PWY-7887|MetaCyc: PWY-7892|Reactome: R-HSA-6787450 AFK25_12950 ba0513e96c09b98e273f58fe2d6530dc 320 SUPERFAMILY SSF55608 120 222 3.74E-16 T 11-10-2018 IPR027434 Homing endonuclease AFK25_12950 ba0513e96c09b98e273f58fe2d6530dc 320 Gene3D G3DSA:1.10.10.10 216 310 2.9E-38 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_12950 ba0513e96c09b98e273f58fe2d6530dc 320 Gene3D G3DSA:3.10.28.10 1 215 4.9E-66 T 11-10-2018 IPR027434 Homing endonuclease AFK25_12950 ba0513e96c09b98e273f58fe2d6530dc 320 Pfam PF14527 WhiA LAGLIDADG-like domain 125 218 6.4E-35 T 11-10-2018 IPR039518 WhiA, LAGLIDADG-like domain AFK25_12950 ba0513e96c09b98e273f58fe2d6530dc 320 Hamap MF_01420 Putative sporulation transcription regulator WhiA [whiA]. 3 308 35.941 T 11-10-2018 IPR003802 Sporulation regulator WhiA GO:0043937 AFK25_12950 ba0513e96c09b98e273f58fe2d6530dc 320 Pfam PF02650 WhiA C-terminal HTH domain 221 305 1.6E-36 T 11-10-2018 IPR023054 Sporulation regulator WhiA, C-terminal AFK25_12950 ba0513e96c09b98e273f58fe2d6530dc 320 Pfam PF10298 WhiA N-terminal LAGLIDADG-like domain 19 103 5.8E-36 T 11-10-2018 IPR018478 Sporulation transcription regulator WhiA, N-terminal domain AFK25_12950 ba0513e96c09b98e273f58fe2d6530dc 320 TIGRFAM TIGR00647 DNA_bind_WhiA: DNA-binding protein WhiA 4 306 6.7E-133 T 11-10-2018 IPR033981 Sporulation regulator WhiA-like AFK25_01200 19952995e184b3b7f7d51061578adbd0 157 Pfam PF02367 Threonylcarbamoyl adenosine biosynthesis protein TsaE 9 130 2.5E-37 T 11-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 AFK25_01200 19952995e184b3b7f7d51061578adbd0 157 SUPERFAMILY SSF52540 24 126 1.13E-21 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_01200 19952995e184b3b7f7d51061578adbd0 157 Gene3D G3DSA:3.40.50.300 2 150 1.3E-40 T 11-10-2018 AFK25_01200 19952995e184b3b7f7d51061578adbd0 157 TIGRFAM TIGR00150 T6A_YjeE: tRNA threonylcarbamoyl adenosine modification protein YjeE 14 132 4.6E-40 T 11-10-2018 IPR003442 tRNA threonylcarbamoyl adenosine modification protein TsaE GO:0002949 AFK25_01990 624223f9729792931ad750fb4d6160d2 153 Pfam PF00578 AhpC/TSA family 2 126 4.3E-42 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFK25_01990 624223f9729792931ad750fb4d6160d2 153 Gene3D G3DSA:3.40.30.10 1 149 5.1E-56 T 11-10-2018 AFK25_01990 624223f9729792931ad750fb4d6160d2 153 SUPERFAMILY SSF52833 3 147 3.14E-57 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_01990 624223f9729792931ad750fb4d6160d2 153 PIRSF PIRSF000239 1 152 2.0E-29 T 11-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFK25_13090 f77ec337d9eed3222dc2b9799356653a 408 Pfam PF01551 Peptidase family M23 298 402 2.2E-27 T 11-10-2018 IPR016047 Peptidase M23 AFK25_13090 f77ec337d9eed3222dc2b9799356653a 408 SUPERFAMILY SSF51261 189 405 5.23E-46 T 11-10-2018 IPR011055 Duplicated hybrid motif AFK25_13090 f77ec337d9eed3222dc2b9799356653a 408 Gene3D G3DSA:2.70.70.10 158 407 5.2E-38 T 11-10-2018 IPR011055 Duplicated hybrid motif AFK25_11180 970ec9d1d4522c2b81f78bb8b105d091 341 SUPERFAMILY SSF48179 183 332 2.72E-72 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFK25_11180 970ec9d1d4522c2b81f78bb8b105d091 341 Gene3D G3DSA:3.40.50.720 1 181 1.4E-82 T 11-10-2018 AFK25_11180 970ec9d1d4522c2b81f78bb8b105d091 341 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 328 46.014 T 11-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFK25_11180 970ec9d1d4522c2b81f78bb8b105d091 341 PIRSF PIRSF000116 201 332 4.0E-16 T 11-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFK25_11180 970ec9d1d4522c2b81f78bb8b105d091 341 PIRSF PIRSF000116 3 205 2.4E-44 T 11-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFK25_11180 970ec9d1d4522c2b81f78bb8b105d091 341 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 183 325 1.5E-67 T 11-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFK25_11180 970ec9d1d4522c2b81f78bb8b105d091 341 Gene3D G3DSA:1.10.3730.40 182 336 1.7E-71 T 11-10-2018 AFK25_11180 970ec9d1d4522c2b81f78bb8b105d091 341 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 177 2.3E-80 T 11-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFK25_11180 970ec9d1d4522c2b81f78bb8b105d091 341 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 326 5.2E-149 T 11-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AFK25_11180 970ec9d1d4522c2b81f78bb8b105d091 341 SUPERFAMILY SSF51735 3 182 3.4E-77 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_11605 5743fbdb03089a8aed1734bc2324cfc1 312 SUPERFAMILY SSF56327 151 309 8.65E-54 T 11-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 AFK25_11605 5743fbdb03089a8aed1734bc2324cfc1 312 PIRSF PIRSF000102 2 312 8.2E-106 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFK25_11605 5743fbdb03089a8aed1734bc2324cfc1 312 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 151 309 2.0E-28 T 11-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 AFK25_11605 5743fbdb03089a8aed1734bc2324cfc1 312 PRINTS PR00086 L-lactate dehydrogenase signature 7 31 1.4E-30 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFK25_11605 5743fbdb03089a8aed1734bc2324cfc1 312 PRINTS PR00086 L-lactate dehydrogenase signature 175 188 1.4E-30 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFK25_11605 5743fbdb03089a8aed1734bc2324cfc1 312 PRINTS PR00086 L-lactate dehydrogenase signature 33 57 1.4E-30 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFK25_11605 5743fbdb03089a8aed1734bc2324cfc1 312 PRINTS PR00086 L-lactate dehydrogenase signature 121 141 1.4E-30 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFK25_11605 5743fbdb03089a8aed1734bc2324cfc1 312 PRINTS PR00086 L-lactate dehydrogenase signature 145 163 1.4E-30 T 11-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AFK25_11605 5743fbdb03089a8aed1734bc2324cfc1 312 TIGRFAM TIGR01763 MalateDH_bact: malate dehydrogenase, NAD-dependent 5 311 2.7E-165 T 11-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 AFK25_11605 5743fbdb03089a8aed1734bc2324cfc1 312 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 7 147 1.1E-41 T 11-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 AFK25_11605 5743fbdb03089a8aed1734bc2324cfc1 312 Gene3D G3DSA:3.90.110.10 150 310 8.1E-63 T 11-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 AFK25_11605 5743fbdb03089a8aed1734bc2324cfc1 312 Gene3D G3DSA:3.40.50.720 1 149 1.9E-60 T 11-10-2018 AFK25_11605 5743fbdb03089a8aed1734bc2324cfc1 312 SUPERFAMILY SSF51735 3 147 2.69E-48 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_11605 5743fbdb03089a8aed1734bc2324cfc1 312 Hamap MF_00487 Malate dehydrogenase [mdh]. 6 312 47.061 T 11-10-2018 IPR011275 Malate dehydrogenase, type 3 GO:0016616|GO:0055114 KEGG: 00020+1.1.1.37|KEGG: 00270+1.1.1.37|KEGG: 00620+1.1.1.37|KEGG: 00630+1.1.1.37|KEGG: 00680+1.1.1.37|KEGG: 00710+1.1.1.37|KEGG: 00720+1.1.1.37|MetaCyc: PWY-1622|MetaCyc: PWY-5392|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7115|MetaCyc: PWY-7383 AFK25_00505 e95ef7ade21011435637c0c0f4a0f776 141 Hamap MF_01468 Mini-ribonuclease 3 [mrnC]. 8 134 29.653 T 11-10-2018 IPR008226 Mini-ribonuclease 3 family AFK25_00505 e95ef7ade21011435637c0c0f4a0f776 141 PIRSF PIRSF005520 2 139 1.1E-52 T 11-10-2018 IPR008226 Mini-ribonuclease 3 family AFK25_00505 e95ef7ade21011435637c0c0f4a0f776 141 SMART SM00535 2 139 1.8E-6 T 11-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 AFK25_00505 e95ef7ade21011435637c0c0f4a0f776 141 SUPERFAMILY SSF69065 10 132 4.88E-43 T 11-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 AFK25_00505 e95ef7ade21011435637c0c0f4a0f776 141 Gene3D G3DSA:1.10.1520.10 5 140 2.1E-50 T 11-10-2018 IPR036389 Ribonuclease III, endonuclease domain superfamily GO:0004525|GO:0006396 AFK25_00505 e95ef7ade21011435637c0c0f4a0f776 141 Pfam PF00636 Ribonuclease III domain 18 117 4.0E-17 T 11-10-2018 IPR000999 Ribonuclease III domain GO:0004525|GO:0006396 Reactome: R-HSA-203927 AFK25_07435 06db9d8c7a6f7a40266acfe641422d85 310 SUPERFAMILY SSF103481 193 295 1.01E-15 T 11-10-2018 AFK25_07435 06db9d8c7a6f7a40266acfe641422d85 310 Pfam PF00892 EamA-like transporter family 7 142 9.6E-27 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFK25_07435 06db9d8c7a6f7a40266acfe641422d85 310 Pfam PF00892 EamA-like transporter family 159 292 7.8E-25 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFK25_07435 06db9d8c7a6f7a40266acfe641422d85 310 SUPERFAMILY SSF103481 41 145 3.53E-17 T 11-10-2018 AFK25_00365 4144d7f6b31fc2da8bee19cc34d79c17 460 Gene3D G3DSA:1.10.10.1360 126 210 3.2E-73 T 11-10-2018 AFK25_00365 4144d7f6b31fc2da8bee19cc34d79c17 460 SUPERFAMILY SSF82829 217 323 9.94E-12 T 11-10-2018 AFK25_00365 4144d7f6b31fc2da8bee19cc34d79c17 460 Gene3D G3DSA:1.20.59.30 245 330 3.4E-31 T 11-10-2018 AFK25_00365 4144d7f6b31fc2da8bee19cc34d79c17 460 Pfam PF09179 TilS substrate binding domain 258 322 6.6E-5 T 11-10-2018 IPR015262 tRNA(Ile)-lysidine synthase , substrate-binding domain GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AFK25_00365 4144d7f6b31fc2da8bee19cc34d79c17 460 SUPERFAMILY SSF56037 333 445 4.97E-20 T 11-10-2018 AFK25_00365 4144d7f6b31fc2da8bee19cc34d79c17 460 Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. 5 318 24.916 T 11-10-2018 IPR012094 tRNA(Ile)-lysidine synthase GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AFK25_00365 4144d7f6b31fc2da8bee19cc34d79c17 460 TIGRFAM TIGR02432 lysidine_TilS_N: tRNA(Ile)-lysidine synthetase 21 208 1.8E-63 T 11-10-2018 IPR012795 tRNA(Ile)-lysidine synthase, N-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AFK25_00365 4144d7f6b31fc2da8bee19cc34d79c17 460 SUPERFAMILY SSF52402 6 237 4.39E-58 T 11-10-2018 AFK25_00365 4144d7f6b31fc2da8bee19cc34d79c17 460 TIGRFAM TIGR02433 lysidine_TilS_C: tRNA(Ile)-lysidine synthetase, C-terminal domain 382 428 2.0E-18 T 11-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AFK25_00365 4144d7f6b31fc2da8bee19cc34d79c17 460 Gene3D G3DSA:3.40.50.620 20 164 3.2E-73 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_00365 4144d7f6b31fc2da8bee19cc34d79c17 460 Pfam PF01171 PP-loop family 21 204 1.1E-61 T 11-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 AFK25_00365 4144d7f6b31fc2da8bee19cc34d79c17 460 Pfam PF11734 TilS substrate C-terminal domain 382 442 8.4E-14 T 11-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AFK25_00365 4144d7f6b31fc2da8bee19cc34d79c17 460 SMART SM00977 382 455 7.3E-23 T 11-10-2018 IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal GO:0000166|GO:0005524|GO:0005737|GO:0008033|GO:0016879 AFK25_01930 6e5d8a60021ab5706b4f5cd9782f8feb 337 Pfam PF00005 ABC transporter 27 185 9.9E-29 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_01930 6e5d8a60021ab5706b4f5cd9782f8feb 337 SMART SM00382 35 235 1.1E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_01930 6e5d8a60021ab5706b4f5cd9782f8feb 337 ProSitePatterns PS00211 ABC transporters family signature. 158 172 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_01930 6e5d8a60021ab5706b4f5cd9782f8feb 337 SUPERFAMILY SSF52540 6 255 4.36E-70 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_01930 6e5d8a60021ab5706b4f5cd9782f8feb 337 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 237 301 5.5E-21 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFK25_01930 6e5d8a60021ab5706b4f5cd9782f8feb 337 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 235 321 2.7E-29 T 11-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AFK25_01930 6e5d8a60021ab5706b4f5cd9782f8feb 337 Gene3D G3DSA:3.40.50.300 4 336 2.1E-101 T 11-10-2018 AFK25_13555 346594d614a6468e7d75edd6e68fc482 300 TIGRFAM TIGR04383 acidic_w_LPXTA: processed acidic surface protein 3 298 1.4E-94 T 11-10-2018 IPR030832 Processed acidic surface protein AFK25_13900 a125ba0399ccf6a207a5fbca3e20887c 147 TIGRFAM TIGR00689 rpiB_lacA_lacB: sugar-phosphate isomerase, RpiB/LacA/LacB family 3 146 1.0E-62 T 11-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 AFK25_13900 a125ba0399ccf6a207a5fbca3e20887c 147 SUPERFAMILY SSF89623 2 144 7.98E-60 T 11-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 AFK25_13900 a125ba0399ccf6a207a5fbca3e20887c 147 Pfam PF02502 Ribose/Galactose Isomerase 3 140 1.9E-58 T 11-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 AFK25_13900 a125ba0399ccf6a207a5fbca3e20887c 147 TIGRFAM TIGR01120 rpiB: ribose 5-phosphate isomerase B 2 143 1.5E-55 T 11-10-2018 IPR004785 Ribose 5-phosphate isomerase B GO:0004751|GO:0006098 AFK25_13900 a125ba0399ccf6a207a5fbca3e20887c 147 Gene3D G3DSA:3.40.1400.10 1 147 4.1E-62 T 11-10-2018 IPR036569 Sugar-phosphate isomerase, RpiB/LacA/LacB superfamily GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 AFK25_13900 a125ba0399ccf6a207a5fbca3e20887c 147 PIRSF PIRSF005384 1 147 5.4E-60 T 11-10-2018 IPR003500 Sugar-phosphate isomerase, RpiB/LacA/LacB family GO:0005975|GO:0016853 KEGG: 00052+5.3.1.26 AFK25_01080 af0dc7927a109a40168bc73136827491 468 SUPERFAMILY SSF52540 71 356 2.53E-78 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_01080 af0dc7927a109a40168bc73136827491 468 Hamap MF_01493 DEAD-box ATP-dependent RNA helicase CshA [cshA]. 2 468 44.74 T 11-10-2018 IPR030880 DEAD-box ATP-dependent RNA helicase CshA GO:0004004|GO:0005524|GO:0010501 AFK25_01080 af0dc7927a109a40168bc73136827491 468 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 149 157 - T 11-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site AFK25_01080 af0dc7927a109a40168bc73136827491 468 Gene3D G3DSA:3.40.50.300 1 207 3.9E-79 T 11-10-2018 AFK25_01080 af0dc7927a109a40168bc73136827491 468 Gene3D G3DSA:3.40.50.300 211 456 7.3E-57 T 11-10-2018 AFK25_01080 af0dc7927a109a40168bc73136827491 468 Pfam PF00270 DEAD/DEAH box helicase 26 190 3.1E-51 T 11-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AFK25_01080 af0dc7927a109a40168bc73136827491 468 SMART SM00490 254 335 3.0E-36 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_01080 af0dc7927a109a40168bc73136827491 468 SMART SM00487 21 218 8.2E-68 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFK25_01080 af0dc7927a109a40168bc73136827491 468 Pfam PF00271 Helicase conserved C-terminal domain 227 335 2.9E-30 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_07445 f55c037da7428cecdc8c78d5ed77110a 432 Pfam PF02040 Arsenical pump membrane protein 6 428 1.4E-222 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFK25_07445 f55c037da7428cecdc8c78d5ed77110a 432 PRINTS PR00758 Arsenical pump membrane protein signature 281 305 5.3E-111 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFK25_07445 f55c037da7428cecdc8c78d5ed77110a 432 PRINTS PR00758 Arsenical pump membrane protein signature 104 128 5.3E-111 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFK25_07445 f55c037da7428cecdc8c78d5ed77110a 432 PRINTS PR00758 Arsenical pump membrane protein signature 147 171 5.3E-111 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFK25_07445 f55c037da7428cecdc8c78d5ed77110a 432 PRINTS PR00758 Arsenical pump membrane protein signature 220 245 5.3E-111 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFK25_07445 f55c037da7428cecdc8c78d5ed77110a 432 PRINTS PR00758 Arsenical pump membrane protein signature 400 424 5.3E-111 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFK25_07445 f55c037da7428cecdc8c78d5ed77110a 432 PRINTS PR00758 Arsenical pump membrane protein signature 180 203 5.3E-111 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFK25_07445 f55c037da7428cecdc8c78d5ed77110a 432 PRINTS PR00758 Arsenical pump membrane protein signature 326 348 5.3E-111 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFK25_07445 f55c037da7428cecdc8c78d5ed77110a 432 PRINTS PR00758 Arsenical pump membrane protein signature 367 392 5.3E-111 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFK25_07445 f55c037da7428cecdc8c78d5ed77110a 432 TIGRFAM TIGR00935 2a45: arsenite/antimonite efflux pump membrane protein 5 430 2.4E-226 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFK25_00585 6902f8798c0326ee52dae96ff0d5baf0 156 Gene3D G3DSA:1.10.455.10 2 156 1.5E-67 T 11-10-2018 IPR036823 Ribosomal protein S7 domain superfamily AFK25_00585 6902f8798c0326ee52dae96ff0d5baf0 156 ProSitePatterns PS00052 Ribosomal protein S7 signature. 20 46 - T 11-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00585 6902f8798c0326ee52dae96ff0d5baf0 156 SUPERFAMILY SSF47973 1 149 8.89E-66 T 11-10-2018 IPR036823 Ribosomal protein S7 domain superfamily AFK25_00585 6902f8798c0326ee52dae96ff0d5baf0 156 PIRSF PIRSF002122 5 156 1.6E-62 T 11-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 AFK25_00585 6902f8798c0326ee52dae96ff0d5baf0 156 TIGRFAM TIGR01029 rpsG_bact: ribosomal protein uS7 3 156 4.9E-73 T 11-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 AFK25_00585 6902f8798c0326ee52dae96ff0d5baf0 156 Hamap MF_00480_B 30S ribosomal protein S7 [rpsG]. 1 156 36.906 T 11-10-2018 IPR005717 Ribosomal protein S7, bacterial/organellar-type GO:0003735|GO:0006412|GO:0015935 AFK25_00585 6902f8798c0326ee52dae96ff0d5baf0 156 Pfam PF00177 Ribosomal protein S7p/S5e 1 149 1.4E-70 T 11-10-2018 IPR023798 Ribosomal protein S7 domain AFK25_05555 618508ac9924bf2002807e91bee48d8a 75 Hamap MF_00088 UPF0109 protein . 1 74 19.404 T 11-10-2018 IPR020627 Uncharacterised protein family UPF0109 AFK25_05555 618508ac9924bf2002807e91bee48d8a 75 Gene3D G3DSA:3.30.1370.10 19 74 1.3E-5 T 11-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AFK25_05555 618508ac9924bf2002807e91bee48d8a 75 Pfam PF13083 KH domain 2 72 2.1E-20 T 11-10-2018 AFK25_05555 618508ac9924bf2002807e91bee48d8a 75 SUPERFAMILY SSF54814 15 61 1.05E-6 T 11-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AFK25_01590 3ef2e44910d592d2818fced5a7ae4b06 404 Pfam PF07690 Major Facilitator Superfamily 14 345 1.4E-40 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFK25_01590 3ef2e44910d592d2818fced5a7ae4b06 404 SUPERFAMILY SSF103473 8 387 4.58E-56 T 11-10-2018 IPR036259 MFS transporter superfamily AFK25_01590 3ef2e44910d592d2818fced5a7ae4b06 404 Gene3D G3DSA:1.20.1250.20 10 384 1.4E-50 T 11-10-2018 AFK25_04370 6f2cdb138f44c9b11bbed8bdb4369d18 497 Pfam PF00005 ABC transporter 272 423 2.2E-17 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_04370 6f2cdb138f44c9b11bbed8bdb4369d18 497 SUPERFAMILY SSF52540 272 482 1.01E-36 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_04370 6f2cdb138f44c9b11bbed8bdb4369d18 497 SMART SM00382 279 478 1.6E-4 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_04370 6f2cdb138f44c9b11bbed8bdb4369d18 497 SMART SM00382 28 228 1.5E-7 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_04370 6f2cdb138f44c9b11bbed8bdb4369d18 497 Gene3D G3DSA:3.40.50.300 2 239 3.5E-57 T 11-10-2018 AFK25_04370 6f2cdb138f44c9b11bbed8bdb4369d18 497 SUPERFAMILY SSF52540 4 227 5.65E-56 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_04370 6f2cdb138f44c9b11bbed8bdb4369d18 497 Gene3D G3DSA:3.40.50.300 267 493 4.3E-36 T 11-10-2018 AFK25_04370 6f2cdb138f44c9b11bbed8bdb4369d18 497 Pfam PF00005 ABC transporter 19 172 6.9E-28 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_04370 6f2cdb138f44c9b11bbed8bdb4369d18 497 ProSitePatterns PS00211 ABC transporters family signature. 396 410 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_14570 409117bbd89f74bbec223f12e4d23b96 657 PIRSF PIRSF026583 1 657 1.0E-271 T 11-10-2018 IPR014528 Cyclic-di-AMP phosphodiesterase GdpP/PdeA AFK25_14570 409117bbd89f74bbec223f12e4d23b96 657 SUPERFAMILY SSF64182 338 640 2.75E-67 T 11-10-2018 IPR038763 DHH phosphoesterase superfamily AFK25_14570 409117bbd89f74bbec223f12e4d23b96 657 Gene3D G3DSA:3.30.450.20 52 156 1.5E-34 T 11-10-2018 AFK25_14570 409117bbd89f74bbec223f12e4d23b96 657 Gene3D G3DSA:3.90.1640.10 322 541 4.5E-53 T 11-10-2018 AFK25_14570 409117bbd89f74bbec223f12e4d23b96 657 Gene3D G3DSA:3.10.310.30 565 653 9.4E-10 T 11-10-2018 AFK25_14570 409117bbd89f74bbec223f12e4d23b96 657 Gene3D G3DSA:3.30.70.270 157 304 3.5E-5 T 11-10-2018 AFK25_14570 409117bbd89f74bbec223f12e4d23b96 657 Pfam PF02272 DHHA1 domain 519 647 3.1E-14 T 11-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 AFK25_14570 409117bbd89f74bbec223f12e4d23b96 657 Pfam PF01368 DHH family 339 496 2.0E-20 T 11-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AFK25_14570 409117bbd89f74bbec223f12e4d23b96 657 SMART SM00267 147 299 3.3E-6 T 11-10-2018 IPR000160 GGDEF domain AFK25_02925 b70aa3fbcb0f070add7de6d69c5176be 244 Pfam PF12706 Beta-lactamase superfamily domain 30 211 9.2E-22 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_02925 b70aa3fbcb0f070add7de6d69c5176be 244 SMART SM00849 18 211 3.1E-15 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_02925 b70aa3fbcb0f070add7de6d69c5176be 244 SUPERFAMILY SSF56281 1 242 5.11E-57 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_02925 b70aa3fbcb0f070add7de6d69c5176be 244 Gene3D G3DSA:3.60.15.10 1 244 8.9E-89 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_07065 13f4a5f590f6f98f67a69b5a762e1bc3 501 Pfam PF07690 Major Facilitator Superfamily 15 406 7.1E-62 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFK25_07065 13f4a5f590f6f98f67a69b5a762e1bc3 501 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 11 485 2.7E-86 T 11-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AFK25_07065 13f4a5f590f6f98f67a69b5a762e1bc3 501 Gene3D G3DSA:1.20.1250.20 262 495 3.6E-20 T 11-10-2018 AFK25_07065 13f4a5f590f6f98f67a69b5a762e1bc3 501 Gene3D G3DSA:1.20.1720.10 11 218 4.8E-58 T 11-10-2018 AFK25_07065 13f4a5f590f6f98f67a69b5a762e1bc3 501 SUPERFAMILY SSF103473 1 492 1.57E-78 T 11-10-2018 IPR036259 MFS transporter superfamily AFK25_10845 0a890f5131ca39c7f029f04fc48218f0 151 Gene3D G3DSA:3.10.20.420 20 74 4.9E-23 T 11-10-2018 IPR038118 Bypass-of-forespore C, N-terminal domain superfamily AFK25_10845 0a890f5131ca39c7f029f04fc48218f0 151 Gene3D G3DSA:3.30.70.1740 75 151 5.4E-30 T 11-10-2018 IPR038117 Bypass of forespore C, C-terminal domain superfamily AFK25_10845 0a890f5131ca39c7f029f04fc48218f0 151 Pfam PF08977 Bypass of Forespore C, N terminal 23 72 3.7E-25 T 11-10-2018 IPR015071 Bypass-of-forespore C, N-terminal AFK25_10845 0a890f5131ca39c7f029f04fc48218f0 151 Pfam PF08955 BofC C-terminal domain 75 147 9.4E-30 T 11-10-2018 IPR015050 Bypass of forespore C, C-terminal AFK25_09645 cd1fcd85ada0f59e51360dbdcb82eab5 387 SUPERFAMILY SSF89550 2 244 3.73E-15 T 11-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFK25_09645 cd1fcd85ada0f59e51360dbdcb82eab5 387 Gene3D G3DSA:1.10.150.20 312 366 3.2E-6 T 11-10-2018 AFK25_09645 cd1fcd85ada0f59e51360dbdcb82eab5 387 Pfam PF13263 PHP-associated 196 244 1.4E-8 T 11-10-2018 AFK25_09645 cd1fcd85ada0f59e51360dbdcb82eab5 387 SUPERFAMILY SSF47781 308 365 1.39E-5 T 11-10-2018 IPR010994 RuvA domain 2-like AFK25_09645 cd1fcd85ada0f59e51360dbdcb82eab5 387 Gene3D G3DSA:3.20.20.140 1 248 4.6E-17 T 11-10-2018 AFK25_12620 efc11539cb9c4e8b8327d273195e306c 352 Gene3D G3DSA:3.40.50.1100 58 154 4.0E-126 T 11-10-2018 AFK25_12620 efc11539cb9c4e8b8327d273195e306c 352 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 23 315 4.1E-78 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFK25_12620 efc11539cb9c4e8b8327d273195e306c 352 SUPERFAMILY SSF53686 3 347 1.44E-108 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFK25_12620 efc11539cb9c4e8b8327d273195e306c 352 Gene3D G3DSA:3.40.50.1100 9 321 4.0E-126 T 11-10-2018 AFK25_12620 efc11539cb9c4e8b8327d273195e306c 352 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 50 63 - T 11-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 AFK25_12620 efc11539cb9c4e8b8327d273195e306c 352 PIRSF PIRSF038945 1 347 2.2E-157 T 11-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 AFK25_12620 efc11539cb9c4e8b8327d273195e306c 352 TIGRFAM TIGR00260 thrC: threonine synthase 7 322 3.3E-107 T 11-10-2018 IPR004450 Threonine synthase-like AFK25_10215 437468a45b3813996ac5ec5fe6591e1c 141 SUPERFAMILY SSF46785 5 133 4.84E-36 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_10215 437468a45b3813996ac5ec5fe6591e1c 141 Pfam PF01475 Ferric uptake regulator family 12 129 2.5E-30 T 11-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 AFK25_10215 437468a45b3813996ac5ec5fe6591e1c 141 Gene3D G3DSA:1.10.10.10 1 83 4.3E-19 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_10215 437468a45b3813996ac5ec5fe6591e1c 141 Gene3D G3DSA:3.30.1490.190 87 140 6.4E-14 T 11-10-2018 AFK25_14050 10943ea5706d5bd1c2f3eb5635ca07ab 290 SUPERFAMILY SSF52768 12 289 3.96E-87 T 11-10-2018 IPR023696 Ureohydrolase domain superfamily AFK25_14050 10943ea5706d5bd1c2f3eb5635ca07ab 290 Pfam PF00491 Arginase family 23 285 7.9E-81 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 AFK25_14050 10943ea5706d5bd1c2f3eb5635ca07ab 290 ProSitePatterns PS01053 Arginase family signature. 214 235 - T 11-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 AFK25_14050 10943ea5706d5bd1c2f3eb5635ca07ab 290 TIGRFAM TIGR01230 agmatinase: agmatinase 11 286 7.9E-119 T 11-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 AFK25_14050 10943ea5706d5bd1c2f3eb5635ca07ab 290 PIRSF PIRSF036979 1 290 1.4E-100 T 11-10-2018 IPR006035 Ureohydrolase GO:0046872 AFK25_14050 10943ea5706d5bd1c2f3eb5635ca07ab 290 Gene3D G3DSA:3.40.800.10 16 289 1.5E-96 T 11-10-2018 AFK25_00730 669bebeb569df7ca3f303c93d202346f 121 TIGRFAM TIGR03631 uS13_bact: ribosomal protein uS13 3 114 8.4E-55 T 11-10-2018 IPR019980 Ribosomal protein S13, bacterial-type GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00730 669bebeb569df7ca3f303c93d202346f 121 Pfam PF00416 Ribosomal protein S13/S18 3 108 2.2E-35 T 11-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00730 669bebeb569df7ca3f303c93d202346f 121 Gene3D G3DSA:4.10.910.10 72 121 1.3E-26 T 11-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00730 669bebeb569df7ca3f303c93d202346f 121 ProSitePatterns PS00646 Ribosomal protein S13 signature. 87 100 - T 11-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00730 669bebeb569df7ca3f303c93d202346f 121 Gene3D G3DSA:1.10.8.50 1 71 2.5E-30 T 11-10-2018 AFK25_00730 669bebeb569df7ca3f303c93d202346f 121 SUPERFAMILY SSF46946 2 114 1.21E-46 T 11-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AFK25_00730 669bebeb569df7ca3f303c93d202346f 121 PIRSF PIRSF002134 1 121 2.6E-44 T 11-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00730 669bebeb569df7ca3f303c93d202346f 121 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 1 118 28.386 T 11-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_08305 24151067c9f260f5bffd1fe3d16397c9 385 Gene3D G3DSA:3.30.1540.10 226 317 3.4E-141 T 11-10-2018 AFK25_08305 24151067c9f260f5bffd1fe3d16397c9 385 SUPERFAMILY SSF89796 3 373 2.49E-141 T 11-10-2018 IPR023606 CoA-transferase family III domain superfamily AFK25_08305 24151067c9f260f5bffd1fe3d16397c9 385 Pfam PF02515 CoA-transferase family III 5 372 6.8E-140 T 11-10-2018 IPR003673 CoA-transferase family III GO:0003824 AFK25_08305 24151067c9f260f5bffd1fe3d16397c9 385 Gene3D G3DSA:3.40.50.10540 5 355 3.4E-141 T 11-10-2018 IPR023606 CoA-transferase family III domain superfamily AFK25_08280 b6709d501a0673f7922678892b3421ec 491 Gene3D G3DSA:3.40.605.10 20 474 2.2E-174 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFK25_08280 b6709d501a0673f7922678892b3421ec 491 Gene3D G3DSA:3.40.309.10 250 444 2.2E-174 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFK25_08280 b6709d501a0673f7922678892b3421ec 491 SUPERFAMILY SSF53720 4 480 6.15E-170 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFK25_08280 b6709d501a0673f7922678892b3421ec 491 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 274 285 - T 11-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 AFK25_08280 b6709d501a0673f7922678892b3421ec 491 Pfam PF00171 Aldehyde dehydrogenase family 11 476 2.5E-175 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFK25_08280 b6709d501a0673f7922678892b3421ec 491 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 246 253 - T 11-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 AFK25_10870 00594e74958e0d36f248052581e61edc 306 TIGRFAM TIGR02899 spore_safA: spore coat assembly protein SafA 6 49 1.4E-24 T 11-10-2018 IPR014248 Spore coat assembly protein SafA AFK25_10870 00594e74958e0d36f248052581e61edc 306 SMART SM00257 3 48 1.7E-17 T 11-10-2018 IPR018392 LysM domain AFK25_10870 00594e74958e0d36f248052581e61edc 306 SUPERFAMILY SSF54106 2 49 1.7E-12 T 11-10-2018 AFK25_10870 00594e74958e0d36f248052581e61edc 306 Gene3D G3DSA:3.10.350.10 1 61 2.7E-17 T 11-10-2018 IPR036779 LysM domain superfamily AFK25_10870 00594e74958e0d36f248052581e61edc 306 Pfam PF01476 LysM domain 4 48 3.2E-16 T 11-10-2018 IPR018392 LysM domain AFK25_07240 34ff307e61596c7f25bf44a866ad3905 240 SMART SM00345 9 68 5.5E-15 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_07240 34ff307e61596c7f25bf44a866ad3905 240 Pfam PF07702 UTRA domain 92 229 6.4E-30 T 11-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFK25_07240 34ff307e61596c7f25bf44a866ad3905 240 TIGRFAM TIGR02404 trehalos_R_Bsub: trehalose operon repressor 5 236 8.2E-97 T 11-10-2018 IPR012770 Trehalose operon transcriptional repressor AFK25_07240 34ff307e61596c7f25bf44a866ad3905 240 SUPERFAMILY SSF46785 3 72 1.52E-18 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_07240 34ff307e61596c7f25bf44a866ad3905 240 Pfam PF00392 Bacterial regulatory proteins, gntR family 6 68 2.2E-17 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_07240 34ff307e61596c7f25bf44a866ad3905 240 Gene3D G3DSA:1.10.10.10 4 71 1.5E-20 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_07240 34ff307e61596c7f25bf44a866ad3905 240 SUPERFAMILY SSF64288 74 234 1.73E-41 T 11-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AFK25_07240 34ff307e61596c7f25bf44a866ad3905 240 SMART SM00866 90 229 8.7E-29 T 11-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFK25_07240 34ff307e61596c7f25bf44a866ad3905 240 Gene3D G3DSA:3.40.1410.10 88 228 8.9E-31 T 11-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AFK25_07240 34ff307e61596c7f25bf44a866ad3905 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 42 58 3.2E-8 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_07240 34ff307e61596c7f25bf44a866ad3905 240 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 28 42 3.2E-8 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_08815 e3e1ce32f9944ccfc4ca835115d3bd5d 110 PIRSF PIRSF029904 1 110 3.6E-54 T 11-10-2018 IPR012359 NTP pyrophosphohydrolase MazG-related, YpjD AFK25_08815 e3e1ce32f9944ccfc4ca835115d3bd5d 110 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 24 103 1.8E-19 T 11-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core AFK25_08815 e3e1ce32f9944ccfc4ca835115d3bd5d 110 SUPERFAMILY SSF101386 4 103 1.47E-27 T 11-10-2018 AFK25_08815 e3e1ce32f9944ccfc4ca835115d3bd5d 110 Gene3D G3DSA:1.10.287.1080 1 110 2.3E-36 T 11-10-2018 AFK25_04975 f66957f94b9c6f18fbfa8d39dc2eecbf 194 TIGRFAM TIGR02898 spore_YhcN_YlaJ: sporulation lipoprotein, YhcN/YlaJ family 7 151 2.0E-39 T 11-10-2018 IPR014247 Sporulation lipoprotein YhcN/YlaJ GO:0030435 AFK25_04975 f66957f94b9c6f18fbfa8d39dc2eecbf 194 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 27 149 6.8E-15 T 11-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like AFK25_03100 d0ac07f7e9ad29ef66ef9a55b94be47b 59 SUPERFAMILY SSF140500 5 44 3.14E-13 T 11-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 AFK25_03100 d0ac07f7e9ad29ef66ef9a55b94be47b 59 Pfam PF09388 Spo0E like sporulation regulatory protein 5 40 4.8E-15 T 11-10-2018 IPR018540 Aspartyl-phosphate phosphatase Spo0E-like GO:0043937 AFK25_03100 d0ac07f7e9ad29ef66ef9a55b94be47b 59 Gene3D G3DSA:1.20.58.990 2 53 2.8E-16 T 11-10-2018 IPR037208 Aspartyl-phosphate phosphatase Spo0E-like superfamily GO:0043937 AFK25_04750 523ba12d8094c7ffef3d83b7d00b4807 366 Pfam PF03845 Spore germination protein 11 325 5.8E-70 T 11-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 AFK25_04750 523ba12d8094c7ffef3d83b7d00b4807 366 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 11 359 1.5E-46 T 11-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 AFK25_11280 94af33c456e3f9f46572f8cfde0489f6 240 SUPERFAMILY SSF53448 1 209 1.28E-40 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_11280 94af33c456e3f9f46572f8cfde0489f6 240 Pfam PF00535 Glycosyl transferase family 2 5 167 4.9E-24 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFK25_11280 94af33c456e3f9f46572f8cfde0489f6 240 Gene3D G3DSA:3.90.550.10 1 240 4.9E-48 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_14635 742bf9a742850081ee73a090289f107f 237 SUPERFAMILY SSF53335 2 236 2.65E-47 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_14635 742bf9a742850081ee73a090289f107f 237 Hamap MF_00074 Ribosomal RNA small subunit methyltransferase G [rsmG]. 14 213 28.392 T 11-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 AFK25_14635 742bf9a742850081ee73a090289f107f 237 TIGRFAM TIGR00138 rsmG_gidB: 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG 25 214 2.4E-51 T 11-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 AFK25_14635 742bf9a742850081ee73a090289f107f 237 Gene3D G3DSA:3.40.50.150 1 237 5.3E-86 T 11-10-2018 AFK25_14635 742bf9a742850081ee73a090289f107f 237 PIRSF PIRSF003078 1 219 3.4E-59 T 11-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 AFK25_14635 742bf9a742850081ee73a090289f107f 237 Pfam PF02527 rRNA small subunit methyltransferase G 21 201 2.1E-56 T 11-10-2018 IPR003682 rRNA small subunit methyltransferase G GO:0005737|GO:0006364|GO:0008649 AFK25_12130 e1ffee1e88fb1b7913cc79967b301ea3 321 Gene3D G3DSA:1.10.1760.20 1 204 3.4E-62 T 11-10-2018 AFK25_12130 e1ffee1e88fb1b7913cc79967b301ea3 321 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 204 1.2E-62 T 11-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 AFK25_12130 e1ffee1e88fb1b7913cc79967b301ea3 321 Pfam PF13190 PDGLE domain 222 308 1.5E-23 T 11-10-2018 IPR025937 PDGLE domain AFK25_07830 27e287629da00f4e911dc5b72e3841aa 443 Pfam PF05048 Periplasmic copper-binding protein (NosD) 138 355 5.8E-42 T 11-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AFK25_07830 27e287629da00f4e911dc5b72e3841aa 443 SUPERFAMILY SSF51126 25 386 4.66E-50 T 11-10-2018 IPR011050 Pectin lyase fold/virulence factor AFK25_07830 27e287629da00f4e911dc5b72e3841aa 443 Gene3D G3DSA:2.160.20.10 28 347 1.3E-30 T 11-10-2018 IPR012334 Pectin lyase fold AFK25_07830 27e287629da00f4e911dc5b72e3841aa 443 SMART SM00710 132 160 1400.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat AFK25_07830 27e287629da00f4e911dc5b72e3841aa 443 SMART SM00710 84 109 70.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat AFK25_07830 27e287629da00f4e911dc5b72e3841aa 443 SMART SM00710 227 252 4400.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat AFK25_07830 27e287629da00f4e911dc5b72e3841aa 443 SMART SM00710 110 131 8.9 T 11-10-2018 IPR006626 Parallel beta-helix repeat AFK25_07830 27e287629da00f4e911dc5b72e3841aa 443 SMART SM00710 183 204 67.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat AFK25_07830 27e287629da00f4e911dc5b72e3841aa 443 SMART SM00710 161 182 220.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat AFK25_07830 27e287629da00f4e911dc5b72e3841aa 443 SMART SM00710 275 306 7900.0 T 11-10-2018 IPR006626 Parallel beta-helix repeat AFK25_07830 27e287629da00f4e911dc5b72e3841aa 443 TIGRFAM TIGR04247 NosD_copper_fam: nitrous oxide reductase family maturation protein NosD 31 399 5.3E-102 T 11-10-2018 IPR026464 Nitrous oxide reductase family maturation protein NosD AFK25_07830 27e287629da00f4e911dc5b72e3841aa 443 SMART SM00722 38 181 3.6E-10 T 11-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain AFK25_13190 3e1d72aeaf63db5c1f679bad06d3072a 365 Gene3D G3DSA:3.40.50.11190 4 175 6.8E-48 T 11-10-2018 AFK25_13190 3e1d72aeaf63db5c1f679bad06d3072a 365 Pfam PF04101 Glycosyltransferase family 28 C-terminal domain 199 339 3.7E-7 T 11-10-2018 IPR007235 Glycosyl transferase, family 28, C-terminal GO:0016758 KEGG: 00550+2.4.1.227|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-5633231 AFK25_13190 3e1d72aeaf63db5c1f679bad06d3072a 365 SUPERFAMILY SSF53756 17 333 2.07E-10 T 11-10-2018 AFK25_13190 3e1d72aeaf63db5c1f679bad06d3072a 365 TIGRFAM TIGR03590 PseG: UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase 4 305 9.9E-98 T 11-10-2018 IPR020023 UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose hydrolase AFK25_13190 3e1d72aeaf63db5c1f679bad06d3072a 365 Gene3D G3DSA:3.40.50.2000 176 321 1.3E-43 T 11-10-2018 AFK25_13015 8f97918a1b525b0d5665d424b59b7d98 392 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 18 373 32.986 T 11-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 AFK25_13015 8f97918a1b525b0d5665d424b59b7d98 392 PIRSF PIRSF001549 2 379 2.1E-84 T 11-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 AFK25_13015 8f97918a1b525b0d5665d424b59b7d98 392 SUPERFAMILY SSF55681 6 327 1.04E-64 T 11-10-2018 AFK25_13015 8f97918a1b525b0d5665d424b59b7d98 392 Pfam PF13393 Histidyl-tRNA synthetase 11 319 2.7E-78 T 11-10-2018 AFK25_13015 8f97918a1b525b0d5665d424b59b7d98 392 Gene3D G3DSA:3.30.930.10 1 323 3.5E-105 T 11-10-2018 AFK25_13015 8f97918a1b525b0d5665d424b59b7d98 392 Gene3D G3DSA:3.40.50.12590 324 392 2.0E-29 T 11-10-2018 AFK25_13015 8f97918a1b525b0d5665d424b59b7d98 392 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 13 323 7.7E-99 T 11-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 AFK25_09195 17a98660e981fe37dd760ea93de76b85 310 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 7 297 1.7E-84 T 11-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 AFK25_09195 17a98660e981fe37dd760ea93de76b85 310 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 310 97.234 T 11-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 AFK25_09195 17a98660e981fe37dd760ea93de76b85 310 Pfam PF03186 CobD/Cbib protein 8 289 7.8E-105 T 11-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 AFK25_05670 01936e7425b37bc3348d5f5ba517b607 339 SUPERFAMILY SSF48029 11 104 1.44E-21 T 11-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical AFK25_05670 01936e7425b37bc3348d5f5ba517b607 339 Gene3D G3DSA:1.10.220.30 108 199 2.4E-34 T 11-10-2018 AFK25_05670 01936e7425b37bc3348d5f5ba517b607 339 Gene3D G3DSA:1.10.220.30 200 339 1.5E-50 T 11-10-2018 AFK25_05670 01936e7425b37bc3348d5f5ba517b607 339 SUPERFAMILY SSF48029 119 330 5.23E-70 T 11-10-2018 IPR011002 Flagellar motor switch protein FliG, alpha-helical AFK25_05670 01936e7425b37bc3348d5f5ba517b607 339 PIRSF PIRSF003161 4 339 1.6E-125 T 11-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFK25_05670 01936e7425b37bc3348d5f5ba517b607 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 277 303 1.8E-79 T 11-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFK25_05670 01936e7425b37bc3348d5f5ba517b607 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 200 225 1.8E-79 T 11-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFK25_05670 01936e7425b37bc3348d5f5ba517b607 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 253 273 1.8E-79 T 11-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFK25_05670 01936e7425b37bc3348d5f5ba517b607 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 119 142 1.8E-79 T 11-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFK25_05670 01936e7425b37bc3348d5f5ba517b607 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 10 26 1.8E-79 T 11-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFK25_05670 01936e7425b37bc3348d5f5ba517b607 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 39 65 1.8E-79 T 11-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFK25_05670 01936e7425b37bc3348d5f5ba517b607 339 PRINTS PR00954 Flagellar motor switch protein FliG signature 231 251 1.8E-79 T 11-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFK25_05670 01936e7425b37bc3348d5f5ba517b607 339 Pfam PF14841 FliG middle domain 120 193 1.4E-31 T 11-10-2018 IPR032779 Flagellar motor switch protein FliG, middle domain AFK25_05670 01936e7425b37bc3348d5f5ba517b607 339 Pfam PF01706 FliG C-terminal domain 223 329 1.0E-43 T 11-10-2018 IPR023087 Flagellar motor switch protein FliG, C-terminal AFK25_05670 01936e7425b37bc3348d5f5ba517b607 339 Pfam PF14842 FliG N-terminal domain 9 112 3.5E-37 T 11-10-2018 IPR028263 Flagellar motor switch protein FliG, N-terminal domain AFK25_05670 01936e7425b37bc3348d5f5ba517b607 339 Gene3D G3DSA:1.10.220.30 2 90 9.1E-21 T 11-10-2018 AFK25_05670 01936e7425b37bc3348d5f5ba517b607 339 TIGRFAM TIGR00207 fliG: flagellar motor switch protein FliG 1 339 4.5E-155 T 11-10-2018 IPR000090 Flagellar motor switch protein FliG GO:0003774|GO:0006935|GO:0009288|GO:0071973 AFK25_01710 3f019b99eb1871546084a82c03c0028c 246 Pfam PF14344 Domain of unknown function (DUF4397) 57 169 7.1E-35 T 11-10-2018 IPR025510 Domain of unknown function DUF4397 AFK25_06620 fbab372331a24310eed4f65881aa972a 216 SUPERFAMILY SSF56784 1 211 2.07E-40 T 11-10-2018 IPR036412 HAD-like superfamily AFK25_06620 fbab372331a24310eed4f65881aa972a 216 Gene3D G3DSA:3.90.1470.20 15 132 1.1E-46 T 11-10-2018 AFK25_06620 fbab372331a24310eed4f65881aa972a 216 Pfam PF12710 haloacid dehalogenase-like hydrolase 7 174 4.4E-11 T 11-10-2018 AFK25_06620 fbab372331a24310eed4f65881aa972a 216 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 5 175 6.4E-26 T 11-10-2018 AFK25_06620 fbab372331a24310eed4f65881aa972a 216 Gene3D G3DSA:3.40.50.1000 7 207 1.1E-46 T 11-10-2018 IPR023214 HAD superfamily AFK25_06620 fbab372331a24310eed4f65881aa972a 216 TIGRFAM TIGR01489 DKMTPPase-SF: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 5 182 7.5E-42 T 11-10-2018 IPR006384 Pyridoxal phosphate phosphatase-related GO:0016791 AFK25_09370 fff4e34ec5641f0c9720e70df9f90a0b 489 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 27 477 9.6E-157 T 11-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 AFK25_09370 fff4e34ec5641f0c9720e70df9f90a0b 489 PIRSF PIRSF005690 4 489 1.8E-140 T 11-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 AFK25_06175 8aeec62c42859c38994c728d2ded7875 133 SUPERFAMILY SSF143422 1 131 3.79E-47 T 11-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 AFK25_06175 8aeec62c42859c38994c728d2ded7875 133 Gene3D G3DSA:3.30.70.1290 1 132 2.4E-48 T 11-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 AFK25_06175 8aeec62c42859c38994c728d2ded7875 133 Pfam PF01797 Transposase IS200 like 11 130 1.9E-43 T 11-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 AFK25_06175 8aeec62c42859c38994c728d2ded7875 133 SMART SM01321 11 130 1.2E-44 T 11-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 AFK25_06205 c18c09805cd8d5d0db8ef362ac5e992a 146 Pfam PF06868 Protein of unknown function (DUF1257) 66 140 6.4E-5 T 11-10-2018 IPR009666 Uncharacterised protein family Ycf35 AFK25_04755 1d04d1205ed6e5d1f701ff80934a207f 370 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 4 369 1.6E-68 T 11-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 AFK25_04755 1d04d1205ed6e5d1f701ff80934a207f 370 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 193 367 1.6E-28 T 11-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 AFK25_04755 1d04d1205ed6e5d1f701ff80934a207f 370 Gene3D G3DSA:3.30.300.210 224 370 3.0E-22 T 11-10-2018 IPR038501 Spore germination GerAC superfamily AFK25_11410 a6b1161d86a6a4ae11f1a9a9f5e6fa29 705 SUPERFAMILY SSF48208 345 618 1.63E-9 T 11-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFK25_11410 a6b1161d86a6a4ae11f1a9a9f5e6fa29 705 Pfam PF03512 Glycosyl hydrolase family 52 20 439 5.0E-177 T 11-10-2018 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00520+3.2.1.37|MetaCyc: PWY-6717 AFK25_11410 a6b1161d86a6a4ae11f1a9a9f5e6fa29 705 PRINTS PR00845 Glycosyl hydrolase family 52 signature 261 281 8.4E-97 T 11-10-2018 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00520+3.2.1.37|MetaCyc: PWY-6717 AFK25_11410 a6b1161d86a6a4ae11f1a9a9f5e6fa29 705 PRINTS PR00845 Glycosyl hydrolase family 52 signature 420 440 8.4E-97 T 11-10-2018 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00520+3.2.1.37|MetaCyc: PWY-6717 AFK25_11410 a6b1161d86a6a4ae11f1a9a9f5e6fa29 705 PRINTS PR00845 Glycosyl hydrolase family 52 signature 87 114 8.4E-97 T 11-10-2018 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00520+3.2.1.37|MetaCyc: PWY-6717 AFK25_11410 a6b1161d86a6a4ae11f1a9a9f5e6fa29 705 PRINTS PR00845 Glycosyl hydrolase family 52 signature 20 47 8.4E-97 T 11-10-2018 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00520+3.2.1.37|MetaCyc: PWY-6717 AFK25_11410 a6b1161d86a6a4ae11f1a9a9f5e6fa29 705 PRINTS PR00845 Glycosyl hydrolase family 52 signature 134 154 8.4E-97 T 11-10-2018 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00520+3.2.1.37|MetaCyc: PWY-6717 AFK25_11410 a6b1161d86a6a4ae11f1a9a9f5e6fa29 705 PRINTS PR00845 Glycosyl hydrolase family 52 signature 307 333 8.4E-97 T 11-10-2018 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00520+3.2.1.37|MetaCyc: PWY-6717 AFK25_11410 a6b1161d86a6a4ae11f1a9a9f5e6fa29 705 PRINTS PR00845 Glycosyl hydrolase family 52 signature 334 363 8.4E-97 T 11-10-2018 IPR000852 Glycoside hydrolase, family 52 GO:0005975|GO:0009044 KEGG: 00520+3.2.1.37|MetaCyc: PWY-6717 AFK25_11410 a6b1161d86a6a4ae11f1a9a9f5e6fa29 705 Gene3D G3DSA:1.50.10.10 396 673 4.3E-6 T 11-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AFK25_13675 04907c4d976c921a05a9002671aca09e 482 Pfam PF13005 zinc-finger binding domain of transposase IS66 117 161 4.2E-12 T 11-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 AFK25_13675 04907c4d976c921a05a9002671aca09e 482 Pfam PF03050 Transposase IS66 family 177 443 3.7E-62 T 11-10-2018 IPR004291 Transposase, IS66 AFK25_05695 f794895147a2b37cc0b2f1332dbb895a 402 Gene3D G3DSA:3.30.750.140 257 380 6.6E-11 T 11-10-2018 IPR038610 FliK-like, C-terminal domain superfamily AFK25_05695 f794895147a2b37cc0b2f1332dbb895a 402 Pfam PF02120 Flagellar hook-length control protein FliK 284 360 1.4E-12 T 11-10-2018 IPR021136 Flagellar hook-length control protein-like, C-terminal AFK25_02525 ae8c7e9df9b5f318643cda2d3dc14371 243 Pfam PF12686 Protein of unknown function (DUF3800) 3 201 4.6E-17 T 11-10-2018 IPR024524 Protein of unknown function DUF3800 AFK25_07325 134fdfec64fa7ac6195bbe86e6cd8ac7 189 SUPERFAMILY SSF58104 2 174 3.66E-38 T 11-10-2018 AFK25_07325 134fdfec64fa7ac6195bbe86e6cd8ac7 189 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 67 96 2.7E-13 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_07325 134fdfec64fa7ac6195bbe86e6cd8ac7 189 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 38 65 2.7E-13 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_07325 134fdfec64fa7ac6195bbe86e6cd8ac7 189 Gene3D G3DSA:1.10.287.950 1 182 1.4E-37 T 11-10-2018 AFK25_07325 134fdfec64fa7ac6195bbe86e6cd8ac7 189 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 4 171 1.4E-31 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_10025 3c39c3791c53e8b8b2bc3826d2d5c059 98 PRINTS PR00813 Bacterial general secretion pathway protein G signature 42 60 1.6E-7 T 11-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 AFK25_10025 3c39c3791c53e8b8b2bc3826d2d5c059 98 PRINTS PR00813 Bacterial general secretion pathway protein G signature 6 31 1.6E-7 T 11-10-2018 IPR000983 Bacterial general secretion pathway protein G-type pilin GO:0008565|GO:0015627|GO:0015628 AFK25_10025 3c39c3791c53e8b8b2bc3826d2d5c059 98 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_10025 3c39c3791c53e8b8b2bc3826d2d5c059 98 PIRSF PIRSF029928 1 97 2.5E-34 T 11-10-2018 IPR016940 ComG operon protein C GO:0030420 AFK25_10025 3c39c3791c53e8b8b2bc3826d2d5c059 98 Gene3D G3DSA:3.30.700.10 7 66 1.3E-10 T 11-10-2018 AFK25_10025 3c39c3791c53e8b8b2bc3826d2d5c059 98 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 26 1.5E-8 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_10025 3c39c3791c53e8b8b2bc3826d2d5c059 98 SUPERFAMILY SSF54523 7 90 3.45E-15 T 11-10-2018 AFK25_10025 3c39c3791c53e8b8b2bc3826d2d5c059 98 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 27 1.3E-7 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_03525 77e7187b241eae9ccce70262a797853c 133 Gene3D G3DSA:1.10.490.10 1 127 1.1E-51 T 11-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 AFK25_03525 77e7187b241eae9ccce70262a797853c 133 SUPERFAMILY SSF46458 4 121 3.96E-40 T 11-10-2018 IPR009050 Globin-like superfamily AFK25_03525 77e7187b241eae9ccce70262a797853c 133 Pfam PF01152 Bacterial-like globin 6 119 3.9E-33 T 11-10-2018 IPR001486 Truncated hemoglobin GO:0019825 AFK25_08820 1f485598da0895b8ff934063d0123c63 304 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 236 290 6.9E-23 T 11-10-2018 IPR019264 Domain of unknown function DUF2179 AFK25_08820 1f485598da0895b8ff934063d0123c63 304 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 24 231 1.2E-64 T 11-10-2018 IPR003740 Uncharacterised membrane protein YitT AFK25_08820 1f485598da0895b8ff934063d0123c63 304 PIRSF PIRSF006483 5 298 7.4E-97 T 11-10-2018 IPR003740 Uncharacterised membrane protein YitT AFK25_08820 1f485598da0895b8ff934063d0123c63 304 Gene3D G3DSA:3.30.70.120 208 283 3.3E-26 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AFK25_06020 7ed26617e0a5aac8c1325041ffab1105 304 Gene3D G3DSA:3.20.20.530 18 303 2.2E-95 T 11-10-2018 AFK25_06020 7ed26617e0a5aac8c1325041ffab1105 304 SUPERFAMILY SSF51730 38 299 4.32E-76 T 11-10-2018 IPR029041 FAD-linked oxidoreductase-like AFK25_06020 7ed26617e0a5aac8c1325041ffab1105 304 Pfam PF01619 Proline dehydrogenase 45 294 3.5E-31 T 11-10-2018 IPR002872 Proline dehydrogenase domain KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922|Reactome: R-HSA-70688 AFK25_06020 7ed26617e0a5aac8c1325041ffab1105 304 PIRSF PIRSF000196 2 304 8.6E-134 T 11-10-2018 IPR008219 Proline dehydrogenase, bacteria and archaea GO:0004657|GO:0010133 KEGG: 00330+1.5.5.2|MetaCyc: PWY-5737|MetaCyc: PWY-6922 AFK25_08855 1af1fd89f63310f20a71d20080b4be55 174 Gene3D G3DSA:4.10.810.10 121 174 1.4E-14 T 11-10-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 AFK25_08855 1af1fd89f63310f20a71d20080b4be55 174 SMART SM00914 134 170 1.9E-9 T 11-10-2018 IPR014957 IDEAL domain AFK25_08855 1af1fd89f63310f20a71d20080b4be55 174 Pfam PF08858 IDEAL domain 137 170 2.5E-13 T 11-10-2018 IPR014957 IDEAL domain AFK25_08855 1af1fd89f63310f20a71d20080b4be55 174 Gene3D G3DSA:1.20.1440.290 1 120 8.7E-54 T 11-10-2018 IPR038091 UPF0302, N-terminal domain superfamily AFK25_08855 1af1fd89f63310f20a71d20080b4be55 174 PIRSF PIRSF007165 1 174 3.0E-75 T 11-10-2018 IPR011188 Uncharacterised protein family UPF0302 AFK25_08855 1af1fd89f63310f20a71d20080b4be55 174 Pfam PF08864 UPF0302 domain 6 110 3.0E-46 T 11-10-2018 IPR014963 Uncharacterised domain UPF0302, N-terminal AFK25_08855 1af1fd89f63310f20a71d20080b4be55 174 Hamap MF_00760 UPF0302 protein . 1 173 30.073 T 11-10-2018 IPR011188 Uncharacterised protein family UPF0302 AFK25_01380 c15aebd05ca15f5e04e8f0390eaeaa3a 377 Pfam PF07537 CamS sex pheromone cAM373 precursor 57 368 3.2E-129 T 11-10-2018 IPR011426 CamS sex pheromone cAM373 AFK25_01380 c15aebd05ca15f5e04e8f0390eaeaa3a 377 PIRSF PIRSF012509 1 376 4.4E-154 T 11-10-2018 IPR011426 CamS sex pheromone cAM373 AFK25_01380 c15aebd05ca15f5e04e8f0390eaeaa3a 377 Gene3D G3DSA:3.10.570.10 42 376 1.7E-137 T 11-10-2018 AFK25_06240 95d56edec33e143d2755a26fe98ed957 235 Pfam PF01323 DSBA-like thioredoxin domain 2 204 1.0E-53 T 11-10-2018 IPR001853 DSBA-like thioredoxin domain GO:0015035 Reactome: R-HSA-156590|Reactome: R-HSA-9033241 AFK25_06240 95d56edec33e143d2755a26fe98ed957 235 Gene3D G3DSA:3.40.30.10 1 208 1.9E-81 T 11-10-2018 AFK25_06240 95d56edec33e143d2755a26fe98ed957 235 SUPERFAMILY SSF52833 1 211 4.22E-53 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_05880 cc1564f41d0b948f51388cff4183f392 94 Pfam PF04296 Protein of unknown function (DUF448) 8 80 2.4E-28 T 11-10-2018 IPR007393 Domain of unknown function DUF448 AFK25_05880 cc1564f41d0b948f51388cff4183f392 94 Gene3D G3DSA:3.30.1230.10 1 93 1.1E-35 T 11-10-2018 IPR035931 YlxR-like superfamily AFK25_05880 cc1564f41d0b948f51388cff4183f392 94 SUPERFAMILY SSF64376 3 86 1.83E-29 T 11-10-2018 IPR035931 YlxR-like superfamily AFK25_12925 e185a37de9614f838d986d7162024ec4 74 Gene3D G3DSA:3.40.30.10 1 74 1.6E-19 T 11-10-2018 AFK25_12925 e185a37de9614f838d986d7162024ec4 74 SUPERFAMILY SSF52833 1 73 8.66E-20 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_12925 e185a37de9614f838d986d7162024ec4 74 Pfam PF05768 Glutaredoxin-like domain (DUF836) 2 72 1.1E-16 T 11-10-2018 IPR008554 Glutaredoxin-like AFK25_12040 714a36bff5272fb1ad37ee7f47e5a097 98 Gene3D G3DSA:3.40.250.10 2 96 2.2E-26 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_12040 714a36bff5272fb1ad37ee7f47e5a097 98 SUPERFAMILY SSF52821 2 93 4.58E-29 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_12040 714a36bff5272fb1ad37ee7f47e5a097 98 Pfam PF00581 Rhodanese-like domain 6 94 1.6E-14 T 11-10-2018 IPR001763 Rhodanese-like domain AFK25_12040 714a36bff5272fb1ad37ee7f47e5a097 98 SMART SM00450 5 98 4.1E-16 T 11-10-2018 IPR001763 Rhodanese-like domain AFK25_04450 b48c3243b865b81aa84329e4a4163f94 343 Pfam PF12698 ABC-2 family transporter protein 18 334 5.9E-33 T 11-10-2018 AFK25_00280 81c609ee6ce57244f1ee006d8ddce777 188 Hamap MF_01334 50S ribosomal protein L25 [rplY]. 1 160 20.207 T 11-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 AFK25_00280 81c609ee6ce57244f1ee006d8ddce777 188 Pfam PF01386 Ribosomal L25p family 1 71 6.3E-16 T 11-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 AFK25_00280 81c609ee6ce57244f1ee006d8ddce777 188 Pfam PF14693 Ribosomal protein TL5, C-terminal domain 79 162 3.1E-26 T 11-10-2018 IPR020057 Ribosomal protein L25, beta domain AFK25_00280 81c609ee6ce57244f1ee006d8ddce777 188 Gene3D G3DSA:2.170.120.20 76 169 1.7E-28 T 11-10-2018 IPR037121 Ribosomal protein L25, C-terminal AFK25_00280 81c609ee6ce57244f1ee006d8ddce777 188 SUPERFAMILY SSF50715 1 162 2.27E-47 T 11-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFK25_00280 81c609ee6ce57244f1ee006d8ddce777 188 Gene3D G3DSA:2.40.240.10 1 74 7.4E-21 T 11-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AFK25_00280 81c609ee6ce57244f1ee006d8ddce777 188 TIGRFAM TIGR00731 bL25_bact_ctc: ribosomal protein bL25, Ctc-form 1 159 2.4E-46 T 11-10-2018 IPR001021 Ribosomal protein L25, long-form GO:0003735|GO:0005840|GO:0006412|GO:0008097 AFK25_00280 81c609ee6ce57244f1ee006d8ddce777 188 ProDom PD012503 RIBOSOMAL L25 50S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN STRESS GENERAL CTC RRNA 1 74 4.0E-13 T 11-10-2018 IPR029751 Ribosomal protein L25 GO:0003735|GO:0005840|GO:0006412|GO:0008097 AFK25_12750 f1355f010d2584a01cbbebc37f76fcf8 274 PIRSF PIRSF002854 1 274 1.1E-107 T 11-10-2018 IPR004872 Lipoprotein NlpA family AFK25_12750 f1355f010d2584a01cbbebc37f76fcf8 274 Gene3D G3DSA:3.40.190.10 35 270 4.2E-99 T 11-10-2018 AFK25_12750 f1355f010d2584a01cbbebc37f76fcf8 274 SUPERFAMILY SSF53850 32 273 3.75E-82 T 11-10-2018 AFK25_12750 f1355f010d2584a01cbbebc37f76fcf8 274 Pfam PF03180 NLPA lipoprotein 33 272 2.9E-91 T 11-10-2018 IPR004872 Lipoprotein NlpA family AFK25_12750 f1355f010d2584a01cbbebc37f76fcf8 274 Gene3D G3DSA:3.40.190.10 114 222 4.2E-99 T 11-10-2018 AFK25_13335 a771fd1aabb179d2d66f74696f9cb0c5 480 SUPERFAMILY SSF53187 299 477 8.16E-58 T 11-10-2018 AFK25_13335 a771fd1aabb179d2d66f74696f9cb0c5 480 Gene3D G3DSA:3.40.630.40 298 480 3.8E-66 T 11-10-2018 AFK25_13335 a771fd1aabb179d2d66f74696f9cb0c5 480 Pfam PF00395 S-layer homology domain 99 141 5.6E-11 T 11-10-2018 IPR001119 S-layer homology domain AFK25_13335 a771fd1aabb179d2d66f74696f9cb0c5 480 Pfam PF00395 S-layer homology domain 164 204 1.6E-7 T 11-10-2018 IPR001119 S-layer homology domain AFK25_13335 a771fd1aabb179d2d66f74696f9cb0c5 480 Pfam PF00395 S-layer homology domain 35 81 1.2E-8 T 11-10-2018 IPR001119 S-layer homology domain AFK25_13335 a771fd1aabb179d2d66f74696f9cb0c5 480 Pfam PF08239 Bacterial SH3 domain 238 288 7.7E-10 T 11-10-2018 IPR003646 SH3-like domain, bacterial-type AFK25_13335 a771fd1aabb179d2d66f74696f9cb0c5 480 SMART SM00287 229 291 3.4E-4 T 11-10-2018 IPR003646 SH3-like domain, bacterial-type AFK25_13335 a771fd1aabb179d2d66f74696f9cb0c5 480 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 302 474 1.0E-58 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 AFK25_13335 a771fd1aabb179d2d66f74696f9cb0c5 480 Gene3D G3DSA:2.30.30.40 230 287 3.1E-14 T 11-10-2018 AFK25_13335 a771fd1aabb179d2d66f74696f9cb0c5 480 SMART SM00646 360 474 4.4E-41 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 AFK25_13030 249722d03e1e5bf41fbfea13e181b30c 311 Pfam PF07670 Nucleoside recognition 175 260 1.5E-7 T 11-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 AFK25_13030 249722d03e1e5bf41fbfea13e181b30c 311 Pfam PF07670 Nucleoside recognition 14 96 4.5E-8 T 11-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 AFK25_13930 37a60bb8d0c9667d3e64bb6902b43e37 283 Gene3D G3DSA:1.10.8.10 4 86 2.7E-16 T 11-10-2018 AFK25_13930 37a60bb8d0c9667d3e64bb6902b43e37 283 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 184 190 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFK25_13930 37a60bb8d0c9667d3e64bb6902b43e37 283 Hamap MF_02126 Release factor glutamine methyltransferase [prmC]. 5 280 39.335 T 11-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 AFK25_13930 37a60bb8d0c9667d3e64bb6902b43e37 283 TIGRFAM TIGR03534 RF_mod_PrmC: protein-(glutamine-N5) methyltransferase, release factor-specific 26 276 3.4E-81 T 11-10-2018 IPR019874 Protein-(glutamine-N5) methyltransferase, release factor-specific GO:0008168 AFK25_13930 37a60bb8d0c9667d3e64bb6902b43e37 283 SUPERFAMILY SSF53335 5 276 3.41E-50 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_13930 37a60bb8d0c9667d3e64bb6902b43e37 283 Pfam PF05175 Methyltransferase small domain 103 191 1.4E-12 T 11-10-2018 IPR007848 Methyltransferase small domain GO:0008168 AFK25_13930 37a60bb8d0c9667d3e64bb6902b43e37 283 TIGRFAM TIGR00536 hemK_fam: methyltransferase, HemK family 5 279 4.1E-70 T 11-10-2018 IPR004556 Modification methylase HemK GO:0006479|GO:0008276 AFK25_13930 37a60bb8d0c9667d3e64bb6902b43e37 283 Gene3D G3DSA:3.40.50.150 87 282 6.6E-60 T 11-10-2018 AFK25_12470 3a9dc416c881dde273f43639ac26b606 59 ProDom PD052450 H SPORE ACID-SOLUBLE SMALL SASP SPORULATION SMALL PROTEIN-RELATED SOLUBLE RBL04815 1 58 7.0E-7 T 11-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 AFK25_12470 3a9dc416c881dde273f43639ac26b606 59 Pfam PF08141 Small acid-soluble spore protein H family 1 58 9.3E-21 T 11-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 AFK25_12470 3a9dc416c881dde273f43639ac26b606 59 Hamap MF_00667 Small, acid-soluble spore protein H [sspH]. 1 59 15.025 T 11-10-2018 IPR012610 Small acid-soluble spore protein, SspH GO:0030436|GO:0042601 AFK25_02860 fbfa3a36ca22aca53b35550559db9bc7 396 SUPERFAMILY SSF53187 6 392 4.79E-90 T 11-10-2018 AFK25_02860 fbfa3a36ca22aca53b35550559db9bc7 396 SUPERFAMILY SSF55031 183 301 2.62E-31 T 11-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain AFK25_02860 fbfa3a36ca22aca53b35550559db9bc7 396 Pfam PF07687 Peptidase dimerisation domain 188 279 3.8E-10 T 11-10-2018 IPR011650 Peptidase M20, dimerisation domain AFK25_02860 fbfa3a36ca22aca53b35550559db9bc7 396 PIRSF PIRSF005962 1 393 1.3E-134 T 11-10-2018 IPR017439 Amidohydrolase GO:0016787 AFK25_02860 fbfa3a36ca22aca53b35550559db9bc7 396 Gene3D G3DSA:3.30.70.360 183 297 2.8E-150 T 11-10-2018 AFK25_02860 fbfa3a36ca22aca53b35550559db9bc7 396 Gene3D G3DSA:3.40.630.10 16 374 2.8E-150 T 11-10-2018 AFK25_02860 fbfa3a36ca22aca53b35550559db9bc7 396 Pfam PF01546 Peptidase family M20/M25/M40 74 381 2.1E-33 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 AFK25_02860 fbfa3a36ca22aca53b35550559db9bc7 396 TIGRFAM TIGR01891 amidohydrolases: amidohydrolase 16 377 3.3E-127 T 11-10-2018 IPR017439 Amidohydrolase GO:0016787 AFK25_08555 98904511569c58075a60fb4769da1083 808 Gene3D G3DSA:3.40.50.300 380 574 8.7E-38 T 11-10-2018 AFK25_08555 98904511569c58075a60fb4769da1083 808 Pfam PF13091 PLD-like domain 16 145 5.5E-11 T 11-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AFK25_08555 98904511569c58075a60fb4769da1083 808 Pfam PF04851 Type III restriction enzyme, res subunit 215 361 3.5E-29 T 11-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFK25_08555 98904511569c58075a60fb4769da1083 808 SUPERFAMILY SSF56024 11 149 2.47E-10 T 11-10-2018 AFK25_08555 98904511569c58075a60fb4769da1083 808 Gene3D G3DSA:3.30.870.10 2 175 4.3E-35 T 11-10-2018 AFK25_08555 98904511569c58075a60fb4769da1083 808 Pfam PF00271 Helicase conserved C-terminal domain 433 534 1.9E-13 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_08555 98904511569c58075a60fb4769da1083 808 SMART SM00487 212 382 1.3E-13 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFK25_08555 98904511569c58075a60fb4769da1083 808 SUPERFAMILY SSF52540 261 549 1.18E-43 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_08555 98904511569c58075a60fb4769da1083 808 Gene3D G3DSA:3.40.50.300 195 376 1.6E-45 T 11-10-2018 AFK25_08555 98904511569c58075a60fb4769da1083 808 SMART SM00490 455 536 8.2E-12 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_07710 ab8ff7d4d2f73261d827dc1d1c2b703e 549 Pfam PF00115 Cytochrome C and Quinol oxidase polypeptide I 15 468 5.5E-89 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_07710 ab8ff7d4d2f73261d827dc1d1c2b703e 549 SUPERFAMILY SSF81442 14 543 4.71E-115 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_07710 ab8ff7d4d2f73261d827dc1d1c2b703e 549 Gene3D G3DSA:1.20.210.10 2 549 1.1E-133 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_07710 ab8ff7d4d2f73261d827dc1d1c2b703e 549 ProSitePatterns PS00077 Heme-copper oxidase catalytic subunit, copper B binding region signature. 219 273 - T 11-10-2018 IPR023615 Cytochrome c oxidase, subunit I, copper-binding site GO:0004129|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_07710 ab8ff7d4d2f73261d827dc1d1c2b703e 549 PRINTS PR01165 Cytochrome c oxidase subunit I signature 288 309 4.4E-14 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_07710 ab8ff7d4d2f73261d827dc1d1c2b703e 549 PRINTS PR01165 Cytochrome c oxidase subunit I signature 419 440 4.4E-14 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_07710 ab8ff7d4d2f73261d827dc1d1c2b703e 549 PRINTS PR01165 Cytochrome c oxidase subunit I signature 51 74 4.4E-14 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_07710 ab8ff7d4d2f73261d827dc1d1c2b703e 549 PRINTS PR01165 Cytochrome c oxidase subunit I signature 119 131 4.4E-14 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_07710 ab8ff7d4d2f73261d827dc1d1c2b703e 549 PRINTS PR01165 Cytochrome c oxidase subunit I signature 217 238 4.4E-14 T 11-10-2018 IPR000883 Cytochrome c oxidase subunit I GO:0004129|GO:0009060|GO:0016021|GO:0020037|GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_03750 551e49e44eb5dc51aad8352199809b1b 256 SUPERFAMILY SSF53213 3 256 1.28E-78 T 11-10-2018 AFK25_03750 551e49e44eb5dc51aad8352199809b1b 256 Pfam PF02900 Catalytic LigB subunit of aromatic ring-opening dioxygenase 5 249 4.9E-41 T 11-10-2018 IPR004183 Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B GO:0006725|GO:0008198|GO:0016491 AFK25_03750 551e49e44eb5dc51aad8352199809b1b 256 PIRSF PIRSF006157 1 256 7.3E-87 T 11-10-2018 IPR014436 Extradiol aromatic ring-opening dioxygenase, DODA-type GO:0008270|GO:0016701|GO:0055114 AFK25_03750 551e49e44eb5dc51aad8352199809b1b 256 Gene3D G3DSA:3.40.830.10 1 256 1.4E-79 T 11-10-2018 AFK25_13450 1f084ec6d10e7b77398cdd2405307a94 122 SUPERFAMILY SSF88723 1 117 3.64E-17 T 11-10-2018 IPR029060 PIN-like domain superfamily AFK25_13450 1f084ec6d10e7b77398cdd2405307a94 122 Gene3D G3DSA:3.40.50.1010 3 121 2.2E-13 T 11-10-2018 AFK25_13450 1f084ec6d10e7b77398cdd2405307a94 122 Pfam PF01850 PIN domain 3 118 5.5E-12 T 11-10-2018 IPR002716 PIN domain AFK25_05660 406bc7e58651126117a29bc5304f0468 95 Pfam PF02049 Flagellar hook-basal body complex protein FliE 12 95 3.6E-32 T 11-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 AFK25_05660 406bc7e58651126117a29bc5304f0468 95 TIGRFAM TIGR00205 fliE: flagellar hook-basal body complex protein FliE 20 95 1.2E-27 T 11-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 AFK25_05660 406bc7e58651126117a29bc5304f0468 95 Hamap MF_00724 Flagellar hook-basal body complex protein FliE [fliE]. 3 95 18.681 T 11-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 AFK25_05660 406bc7e58651126117a29bc5304f0468 95 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 80 93 2.0E-16 T 11-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 AFK25_05660 406bc7e58651126117a29bc5304f0468 95 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 25 41 2.0E-16 T 11-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 AFK25_05660 406bc7e58651126117a29bc5304f0468 95 PRINTS PR01006 Flagellar hook-basal body complex protein FliE signature 59 75 2.0E-16 T 11-10-2018 IPR001624 Flagellar hook-basal body complex protein FliE GO:0003774|GO:0005198|GO:0009288|GO:0071973 AFK25_08845 d55a593eec5855c4e66981bf6fc688d7 169 Pfam PF00355 Rieske [2Fe-2S] domain 52 149 7.1E-14 T 11-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFK25_08845 d55a593eec5855c4e66981bf6fc688d7 169 Gene3D G3DSA:2.102.10.10 39 166 7.8E-25 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFK25_08845 d55a593eec5855c4e66981bf6fc688d7 169 SUPERFAMILY SSF50022 4 160 3.27E-31 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFK25_07510 c8821148a3f179e8cf13842157f54ea5 821 SUPERFAMILY SSF51395 13 115 5.13E-5 T 11-10-2018 AFK25_07510 c8821148a3f179e8cf13842157f54ea5 821 Pfam PF01136 Peptidase family U32 75 300 2.3E-83 T 11-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 AFK25_07510 c8821148a3f179e8cf13842157f54ea5 821 Pfam PF01136 Peptidase family U32 607 806 1.5E-17 T 11-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 AFK25_07510 c8821148a3f179e8cf13842157f54ea5 821 Pfam PF12392 Collagenase 396 516 2.4E-23 T 11-10-2018 IPR020988 Peptidase U32, collagenase AFK25_00370 ae544941fede40ec1e0f88d1187d3093 181 TIGRFAM TIGR01203 HGPRTase: hypoxanthine phosphoribosyltransferase 10 175 2.5E-68 T 11-10-2018 IPR005904 Hypoxanthine phosphoribosyl transferase GO:0004422|GO:0005737|GO:0006166 KEGG: 00230+2.4.2.8|KEGG: 00983+2.4.2.8|MetaCyc: PWY-6599|MetaCyc: PWY-6609|MetaCyc: PWY-6610|MetaCyc: PWY-6620 AFK25_00370 ae544941fede40ec1e0f88d1187d3093 181 SUPERFAMILY SSF53271 2 179 1.44E-61 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like AFK25_00370 ae544941fede40ec1e0f88d1187d3093 181 Gene3D G3DSA:3.40.50.2020 2 181 3.1E-66 T 11-10-2018 AFK25_00370 ae544941fede40ec1e0f88d1187d3093 181 Pfam PF00156 Phosphoribosyl transferase domain 15 161 1.8E-23 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFK25_05840 9a743b635ef22f7b1cd108a3b8c40ebe 254 SUPERFAMILY SSF64005 22 247 3.4E-91 T 11-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 AFK25_05840 9a743b635ef22f7b1cd108a3b8c40ebe 254 Gene3D G3DSA:3.40.1180.10 7 254 5.6E-104 T 11-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 AFK25_05840 9a743b635ef22f7b1cd108a3b8c40ebe 254 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 25 252 6.1E-89 T 11-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFK25_05840 9a743b635ef22f7b1cd108a3b8c40ebe 254 Pfam PF01255 Putative undecaprenyl diphosphate synthase 32 252 1.1E-86 T 11-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFK25_05840 9a743b635ef22f7b1cd108a3b8c40ebe 254 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 198 215 - T 11-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 AFK25_05840 9a743b635ef22f7b1cd108a3b8c40ebe 254 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 25 253 40.772 T 11-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AFK25_10240 4e3689fc4962ba62fc8a3d16e6b42cec 295 Gene3D G3DSA:3.20.20.150 1 295 1.2E-101 T 11-10-2018 AFK25_10240 4e3689fc4962ba62fc8a3d16e6b42cec 295 ProSitePatterns PS00729 AP endonucleases family 2 signature 1. 69 77 - T 11-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 AFK25_10240 4e3689fc4962ba62fc8a3d16e6b42cec 295 Pfam PF01261 Xylose isomerase-like TIM barrel 21 237 1.9E-37 T 11-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFK25_10240 4e3689fc4962ba62fc8a3d16e6b42cec 295 Hamap MF_00152 Probable endonuclease 4 [nfo]. 2 284 43.227 T 11-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 AFK25_10240 4e3689fc4962ba62fc8a3d16e6b42cec 295 ProSitePatterns PS00730 AP endonucleases family 2 signature 2. 175 182 - T 11-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 AFK25_10240 4e3689fc4962ba62fc8a3d16e6b42cec 295 SUPERFAMILY SSF51658 2 292 3.8E-100 T 11-10-2018 IPR036237 Xylose isomerase-like superfamily AFK25_10240 4e3689fc4962ba62fc8a3d16e6b42cec 295 TIGRFAM TIGR00587 nfo: apurinic endonuclease (APN1) 3 281 6.2E-104 T 11-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 AFK25_10240 4e3689fc4962ba62fc8a3d16e6b42cec 295 SMART SM00518 3 284 1.1E-129 T 11-10-2018 IPR001719 AP endonuclease 2 GO:0003677|GO:0006281|GO:0008270 AFK25_10240 4e3689fc4962ba62fc8a3d16e6b42cec 295 ProSitePatterns PS00731 AP endonucleases family 2 signature 3. 213 229 - T 11-10-2018 IPR018246 AP endonuclease 2, zinc binding site GO:0008270 AFK25_08455 2941998b568be2750ad83d51ac5177d9 193 Gene3D G3DSA:3.90.1570.10 3 191 1.6E-32 T 11-10-2018 AFK25_08455 2941998b568be2750ad83d51ac5177d9 193 SUPERFAMILY SSF52980 8 188 6.43E-37 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFK25_08455 2941998b568be2750ad83d51ac5177d9 193 Pfam PF05685 Putative restriction endonuclease 14 182 4.1E-30 T 11-10-2018 IPR008538 Domain of unknown function DUF820 AFK25_06560 86f88e881e761d98b15bec517895923c 119 Pfam PF01022 Bacterial regulatory protein, arsR family 45 84 2.7E-12 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_06560 86f88e881e761d98b15bec517895923c 119 SMART SM00418 38 116 1.1E-24 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_06560 86f88e881e761d98b15bec517895923c 119 Gene3D G3DSA:1.10.10.10 8 117 1.0E-26 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_06560 86f88e881e761d98b15bec517895923c 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 59 70 2.7E-15 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_06560 86f88e881e761d98b15bec517895923c 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 87 102 2.7E-15 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_06560 86f88e881e761d98b15bec517895923c 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 40 55 2.7E-15 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_06560 86f88e881e761d98b15bec517895923c 119 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 72 87 2.7E-15 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_06560 86f88e881e761d98b15bec517895923c 119 SUPERFAMILY SSF46785 24 112 6.88E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_10270 b5c9fd464f75a52caeb6a36d4a60635f 120 PIRSF PIRSF000025 1 120 5.9E-38 T 11-10-2018 IPR012218 Cytochrome c, Bacillus subtilis c550-related GO:0005506|GO:0009055|GO:0016021|GO:0020037 AFK25_10270 b5c9fd464f75a52caeb6a36d4a60635f 120 Gene3D G3DSA:1.10.760.10 51 120 3.6E-26 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFK25_10270 b5c9fd464f75a52caeb6a36d4a60635f 120 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 49 116 6.5E-13 T 11-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_10270 b5c9fd464f75a52caeb6a36d4a60635f 120 SUPERFAMILY SSF46626 9 119 5.08E-19 T 11-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AFK25_14095 fc1cfe593848932a6b30a95060331e9d 223 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 3 79 3.4E-43 T 11-10-2018 IPR014243 Transcription factor, RsfA AFK25_14095 fc1cfe593848932a6b30a95060331e9d 223 Gene3D G3DSA:1.10.10.60 1 56 2.6E-5 T 11-10-2018 AFK25_14095 fc1cfe593848932a6b30a95060331e9d 223 SUPERFAMILY SSF46689 6 61 4.76E-5 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_14095 fc1cfe593848932a6b30a95060331e9d 223 Pfam PF13921 Myb-like DNA-binding domain 9 62 1.3E-5 T 11-10-2018 AFK25_10050 69a949f49a16ae3b76419a2d6c7bb122 80 ProDom PD059814 YQGY TRANSMEMBRANE MEMBRANE PRECURSOR BH2821 SIGNAL 1 79 4.0E-23 T 11-10-2018 IPR020254 Protein of unknown function DUF2626 AFK25_10050 69a949f49a16ae3b76419a2d6c7bb122 80 Pfam PF11117 Protein of unknown function (DUF2626) 1 74 6.0E-37 T 11-10-2018 IPR020254 Protein of unknown function DUF2626 AFK25_08480 0a913fc5f828ab6bff8df56a9fca40be 186 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 94 110 9.5E-4 T 11-10-2018 IPR001451 Hexapeptide repeat AFK25_08480 0a913fc5f828ab6bff8df56a9fca40be 186 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 131 165 2.0E-10 T 11-10-2018 IPR001451 Hexapeptide repeat AFK25_08480 0a913fc5f828ab6bff8df56a9fca40be 186 SMART SM01266 5 59 3.5E-26 T 11-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 AFK25_08480 0a913fc5f828ab6bff8df56a9fca40be 186 Gene3D G3DSA:2.160.10.10 1 185 2.2E-77 T 11-10-2018 AFK25_08480 0a913fc5f828ab6bff8df56a9fca40be 186 Pfam PF12464 Maltose acetyltransferase 7 58 5.0E-20 T 11-10-2018 IPR024688 Maltose/galactoside acetyltransferase GO:0016407 AFK25_08480 0a913fc5f828ab6bff8df56a9fca40be 186 ProSitePatterns PS00101 Hexapeptide-repeat containing-transferases signature. 139 167 - T 11-10-2018 IPR018357 Hexapeptide transferase, conserved site GO:0016740 Reactome: R-HSA-446205 AFK25_08480 0a913fc5f828ab6bff8df56a9fca40be 186 SUPERFAMILY SSF51161 2 184 6.52E-60 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily AFK25_06130 f594e1365824df0adc44a39ec9d543f0 154 SUPERFAMILY SSF55811 3 131 5.28E-28 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFK25_06130 f594e1365824df0adc44a39ec9d543f0 154 Pfam PF00293 NUDIX domain 7 109 9.8E-20 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFK25_06130 f594e1365824df0adc44a39ec9d543f0 154 PRINTS PR00502 NUDIX hydrolase family signature 34 48 4.4E-8 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFK25_06130 f594e1365824df0adc44a39ec9d543f0 154 PRINTS PR00502 NUDIX hydrolase family signature 48 63 4.4E-8 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFK25_06130 f594e1365824df0adc44a39ec9d543f0 154 Gene3D G3DSA:3.90.79.10 1 134 7.2E-29 T 11-10-2018 AFK25_06130 f594e1365824df0adc44a39ec9d543f0 154 ProSitePatterns PS00893 Nudix box signature. 39 60 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFK25_06810 7a52a48faf7de6f3a118fc4676462f6d 519 SUPERFAMILY SSF56801 3 516 1.57E-158 T 11-10-2018 AFK25_06810 7a52a48faf7de6f3a118fc4676462f6d 519 Gene3D G3DSA:3.30.300.310 414 519 3.9E-36 T 11-10-2018 AFK25_06810 7a52a48faf7de6f3a118fc4676462f6d 519 Pfam PF13193 AMP-binding enzyme C-terminal domain 427 503 2.0E-20 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFK25_06810 7a52a48faf7de6f3a118fc4676462f6d 519 Gene3D G3DSA:3.40.50.12780 2 411 3.3E-123 T 11-10-2018 AFK25_06810 7a52a48faf7de6f3a118fc4676462f6d 519 Pfam PF00501 AMP-binding enzyme 9 418 6.4E-108 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFK25_06810 7a52a48faf7de6f3a118fc4676462f6d 519 ProSitePatterns PS00455 Putative AMP-binding domain signature. 166 177 - T 11-10-2018 IPR020845 AMP-binding, conserved site AFK25_10540 846ff99d8f6d839abec071c49bceb600 87 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 83 4.8E-15 T 11-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 AFK25_10540 846ff99d8f6d839abec071c49bceb600 87 Pfam PF09827 CRISPR associated protein Cas2 1 68 2.9E-22 T 11-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 AFK25_10540 846ff99d8f6d839abec071c49bceb600 87 SUPERFAMILY SSF143430 1 83 6.41E-27 T 11-10-2018 AFK25_10540 846ff99d8f6d839abec071c49bceb600 87 Gene3D G3DSA:3.30.70.240 1 65 7.6E-28 T 11-10-2018 AFK25_10540 846ff99d8f6d839abec071c49bceb600 87 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 86 14.745 T 11-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 AFK25_07205 688afaed7c323a956b4a1e75b708fe07 193 SMART SM01207 7 183 3.6E-81 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 AFK25_07205 688afaed7c323a956b4a1e75b708fe07 193 TIGRFAM TIGR00023 TIGR00023: acyl-phosphate glycerol 3-phosphate acyltransferase 2 192 1.3E-70 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 AFK25_07205 688afaed7c323a956b4a1e75b708fe07 193 Hamap MF_01043 Glycerol-3-phosphate acyltransferase [plsY]. 4 191 20.307 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 AFK25_07205 688afaed7c323a956b4a1e75b708fe07 193 Pfam PF02660 Glycerol-3-phosphate acyltransferase 8 182 1.6E-51 T 11-10-2018 IPR003811 Glycerol-3-phosphate acyltransferase, PlsY GO:0005886|GO:0008654|GO:0043772 AFK25_05575 606e796dd7ea601268fe575ede504838 114 PIRSF PIRSF002191 1 114 4.7E-53 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_05575 606e796dd7ea601268fe575ede504838 114 Hamap MF_00402 50S ribosomal protein L19 [rplS]. 2 114 33.259 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_05575 606e796dd7ea601268fe575ede504838 114 PRINTS PR00061 Ribosomal protein L19 signature 34 63 9.8E-43 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_05575 606e796dd7ea601268fe575ede504838 114 PRINTS PR00061 Ribosomal protein L19 signature 88 113 9.8E-43 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_05575 606e796dd7ea601268fe575ede504838 114 PRINTS PR00061 Ribosomal protein L19 signature 4 33 9.8E-43 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_05575 606e796dd7ea601268fe575ede504838 114 TIGRFAM TIGR01024 rplS_bact: ribosomal protein bL19 3 113 7.5E-53 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_05575 606e796dd7ea601268fe575ede504838 114 Pfam PF01245 Ribosomal protein L19 4 112 3.8E-55 T 11-10-2018 IPR001857 Ribosomal protein L19 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_05575 606e796dd7ea601268fe575ede504838 114 SUPERFAMILY SSF50104 1 113 5.82E-50 T 11-10-2018 IPR008991 Translation protein SH3-like domain superfamily AFK25_05575 606e796dd7ea601268fe575ede504838 114 Gene3D G3DSA:2.30.30.790 4 114 1.2E-15 T 11-10-2018 IPR038657 Ribosomal protein L19 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_05575 606e796dd7ea601268fe575ede504838 114 ProSitePatterns PS01015 Ribosomal protein L19 signature. 86 101 - T 11-10-2018 IPR018257 Ribosomal protein L19, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_01005 0e6b14a46a563d37c16dc9a6d73bde76 380 Gene3D G3DSA:2.40.110.10 121 234 2.4E-40 T 11-10-2018 AFK25_01005 0e6b14a46a563d37c16dc9a6d73bde76 380 Gene3D G3DSA:1.10.540.10 1 119 1.7E-46 T 11-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AFK25_01005 0e6b14a46a563d37c16dc9a6d73bde76 380 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 118 4.3E-41 T 11-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AFK25_01005 0e6b14a46a563d37c16dc9a6d73bde76 380 SUPERFAMILY SSF56645 2 243 2.36E-88 T 11-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AFK25_01005 0e6b14a46a563d37c16dc9a6d73bde76 380 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 378 1.8E-54 T 11-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AFK25_01005 0e6b14a46a563d37c16dc9a6d73bde76 380 PIRSF PIRSF016578 3 378 8.4E-23 T 11-10-2018 AFK25_01005 0e6b14a46a563d37c16dc9a6d73bde76 380 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 124 136 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFK25_01005 0e6b14a46a563d37c16dc9a6d73bde76 380 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 218 5.9E-27 T 11-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AFK25_01005 0e6b14a46a563d37c16dc9a6d73bde76 380 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 11-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AFK25_01005 0e6b14a46a563d37c16dc9a6d73bde76 380 SUPERFAMILY SSF47203 229 378 2.09E-62 T 11-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AFK25_01005 0e6b14a46a563d37c16dc9a6d73bde76 380 Gene3D G3DSA:1.20.140.10 235 379 2.4E-60 T 11-10-2018 AFK25_11440 84835f9a3d778bc19707e89785c39367 389 Gene3D G3DSA:1.10.10.10 1 74 2.9E-22 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_11440 84835f9a3d778bc19707e89785c39367 389 SUPERFAMILY SSF53067 79 371 1.35E-55 T 11-10-2018 AFK25_11440 84835f9a3d778bc19707e89785c39367 389 Pfam PF00480 ROK family 82 371 4.3E-69 T 11-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFK25_11440 84835f9a3d778bc19707e89785c39367 389 Gene3D G3DSA:3.30.420.40 86 369 6.8E-94 T 11-10-2018 AFK25_11440 84835f9a3d778bc19707e89785c39367 389 Gene3D G3DSA:3.30.420.40 202 361 6.8E-94 T 11-10-2018 AFK25_11440 84835f9a3d778bc19707e89785c39367 389 SUPERFAMILY SSF46785 7 73 2.59E-19 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_11440 84835f9a3d778bc19707e89785c39367 389 Pfam PF13412 Winged helix-turn-helix DNA-binding 16 55 1.8E-5 T 11-10-2018 AFK25_12875 92c66e9064ed2a7d1f66d0ad1faa7855 77 PRINTS PR01651 Protein-export SecG membrane protein signature 23 37 4.3E-13 T 11-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFK25_12875 92c66e9064ed2a7d1f66d0ad1faa7855 77 PRINTS PR01651 Protein-export SecG membrane protein signature 56 77 4.3E-13 T 11-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFK25_12875 92c66e9064ed2a7d1f66d0ad1faa7855 77 PRINTS PR01651 Protein-export SecG membrane protein signature 3 23 4.3E-13 T 11-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFK25_12875 92c66e9064ed2a7d1f66d0ad1faa7855 77 Pfam PF03840 Preprotein translocase SecG subunit 4 74 4.4E-23 T 11-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFK25_12875 92c66e9064ed2a7d1f66d0ad1faa7855 77 TIGRFAM TIGR00810 secG: preprotein translocase, SecG subunit 2 75 1.4E-24 T 11-10-2018 IPR004692 Preprotein translocase SecG subunit GO:0009306|GO:0015450|GO:0016021 AFK25_02780 a4f64407c0dc69aa03c07299e76f2289 114 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 3 106 2.1E-17 T 11-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA AFK25_02780 a4f64407c0dc69aa03c07299e76f2289 114 SUPERFAMILY SSF158622 1 112 4.45E-26 T 11-10-2018 IPR023378 YheA/YmcA-like domain superfamily AFK25_02780 a4f64407c0dc69aa03c07299e76f2289 114 Gene3D G3DSA:1.20.1500.10 1 113 1.2E-24 T 11-10-2018 IPR023378 YheA/YmcA-like domain superfamily AFK25_06045 b234e836d15482043a65efce3c654bfb 489 SUPERFAMILY SSF52091 385 477 9.03E-9 T 11-10-2018 IPR036513 STAS domain superfamily AFK25_06045 b234e836d15482043a65efce3c654bfb 489 ProSitePatterns PS01130 SLC26A transporters signature. 42 63 - T 11-10-2018 IPR018045 Sulphate anion transporter, conserved site GO:0008271|GO:0008272 Reactome: R-HSA-427601 AFK25_06045 b234e836d15482043a65efce3c654bfb 489 Pfam PF00916 Sulfate permease family 161 354 2.1E-33 T 11-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 AFK25_06045 b234e836d15482043a65efce3c654bfb 489 Pfam PF00916 Sulfate permease family 14 141 1.7E-27 T 11-10-2018 IPR011547 SLC26A/SulP transporter domain GO:0008272|GO:0015116|GO:0016021 AFK25_06045 b234e836d15482043a65efce3c654bfb 489 Gene3D G3DSA:3.30.750.24 382 478 5.2E-24 T 11-10-2018 IPR036513 STAS domain superfamily AFK25_10755 d7c8225100d0879849b9930a912fe1eb 419 Gene3D G3DSA:3.40.630.40 245 419 3.0E-57 T 11-10-2018 AFK25_10755 d7c8225100d0879849b9930a912fe1eb 419 Pfam PF01520 N-acetylmuramoyl-L-alanine amidase 247 414 5.2E-50 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 AFK25_10755 d7c8225100d0879849b9930a912fe1eb 419 Pfam PF08239 Bacterial SH3 domain 34 84 1.4E-9 T 11-10-2018 IPR003646 SH3-like domain, bacterial-type AFK25_10755 d7c8225100d0879849b9930a912fe1eb 419 Pfam PF08239 Bacterial SH3 domain 178 226 6.1E-10 T 11-10-2018 IPR003646 SH3-like domain, bacterial-type AFK25_10755 d7c8225100d0879849b9930a912fe1eb 419 Pfam PF08239 Bacterial SH3 domain 106 156 1.1E-7 T 11-10-2018 IPR003646 SH3-like domain, bacterial-type AFK25_10755 d7c8225100d0879849b9930a912fe1eb 419 PIRSF PIRSF037846 1 418 5.8E-127 T 11-10-2018 IPR017293 N-acetylmuramoyl-L-alanine amidase, YrvJ, predicted MetaCyc: PWY-7883 AFK25_10755 d7c8225100d0879849b9930a912fe1eb 419 Gene3D G3DSA:2.30.30.40 103 157 1.8E-13 T 11-10-2018 AFK25_10755 d7c8225100d0879849b9930a912fe1eb 419 SMART SM00646 306 414 1.5E-34 T 11-10-2018 IPR002508 N-acetylmuramoyl-L-alanine amidase, catalytic domain GO:0008745|GO:0009253 AFK25_10755 d7c8225100d0879849b9930a912fe1eb 419 SUPERFAMILY SSF53187 244 417 2.89E-55 T 11-10-2018 AFK25_10755 d7c8225100d0879849b9930a912fe1eb 419 Gene3D G3DSA:2.30.30.40 19 89 2.1E-15 T 11-10-2018 AFK25_10755 d7c8225100d0879849b9930a912fe1eb 419 Gene3D G3DSA:2.30.30.40 158 233 1.0E-13 T 11-10-2018 AFK25_10755 d7c8225100d0879849b9930a912fe1eb 419 SMART SM00287 25 88 2.7E-8 T 11-10-2018 IPR003646 SH3-like domain, bacterial-type AFK25_10755 d7c8225100d0879849b9930a912fe1eb 419 SMART SM00287 98 160 6.8E-5 T 11-10-2018 IPR003646 SH3-like domain, bacterial-type AFK25_10755 d7c8225100d0879849b9930a912fe1eb 419 SMART SM00287 168 231 1.3E-8 T 11-10-2018 IPR003646 SH3-like domain, bacterial-type AFK25_07635 c57ea992505b4944f430a218460ffa2c 312 Pfam PF01544 CorA-like Mg2+ transporter protein 22 308 5.0E-65 T 11-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 AFK25_07635 c57ea992505b4944f430a218460ffa2c 312 SUPERFAMILY SSF143865 1 247 4.32E-58 T 11-10-2018 AFK25_07635 c57ea992505b4944f430a218460ffa2c 312 Gene3D G3DSA:1.20.58.340 256 312 1.3E-10 T 11-10-2018 AFK25_07635 c57ea992505b4944f430a218460ffa2c 312 SUPERFAMILY SSF144083 248 309 7.59E-15 T 11-10-2018 AFK25_07635 c57ea992505b4944f430a218460ffa2c 312 Gene3D G3DSA:3.30.460.20 4 132 3.0E-28 T 11-10-2018 AFK25_07635 c57ea992505b4944f430a218460ffa2c 312 Gene3D G3DSA:1.20.58.340 133 254 9.9E-30 T 11-10-2018 AFK25_04000 366e9dc6a8888642f70baf4b53489c20 170 SUPERFAMILY SSF53098 33 140 1.19E-8 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_04000 366e9dc6a8888642f70baf4b53489c20 170 Pfam PF13358 DDE superfamily endonuclease 1 143 1.6E-36 T 11-10-2018 IPR038717 Tc1-like transposase, DDE domain AFK25_04000 366e9dc6a8888642f70baf4b53489c20 170 Gene3D G3DSA:3.30.420.470 1 167 5.5E-15 T 11-10-2018 AFK25_01870 506cc8b4be10ebb1265ba29a7ed87357 375 SUPERFAMILY SSF51556 56 338 6.32E-49 T 11-10-2018 IPR032466 Metal-dependent hydrolase AFK25_01870 506cc8b4be10ebb1265ba29a7ed87357 375 Gene3D G3DSA:3.20.20.140 57 334 1.5E-109 T 11-10-2018 AFK25_01870 506cc8b4be10ebb1265ba29a7ed87357 375 Gene3D G3DSA:2.30.40.10 10 368 1.5E-109 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFK25_01870 506cc8b4be10ebb1265ba29a7ed87357 375 Pfam PF01979 Amidohydrolase family 53 368 2.5E-21 T 11-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AFK25_01870 506cc8b4be10ebb1265ba29a7ed87357 375 SUPERFAMILY SSF51338 3 373 3.78E-24 T 11-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AFK25_01970 0a890792a3ca296bfad26b6ea15d8bb6 331 SUPERFAMILY SSF52540 34 250 1.43E-58 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_01970 0a890792a3ca296bfad26b6ea15d8bb6 331 SMART SM00382 49 233 2.2E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_01970 0a890792a3ca296bfad26b6ea15d8bb6 331 Gene3D G3DSA:3.40.50.300 3 282 1.0E-60 T 11-10-2018 AFK25_01970 0a890792a3ca296bfad26b6ea15d8bb6 331 Pfam PF00005 ABC transporter 41 184 6.7E-31 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_04810 b6415d0c5f3941e3e69b209d61ab0503 79 Pfam PF08796 Protein of unknown function (DUF1797) 7 78 1.3E-27 T 11-10-2018 IPR014904 Protein of unknown function DUF1797 AFK25_04810 b6415d0c5f3941e3e69b209d61ab0503 79 SUPERFAMILY SSF143567 2 78 4.84E-28 T 11-10-2018 IPR038073 YkuJ-like superfamily AFK25_04810 b6415d0c5f3941e3e69b209d61ab0503 79 Gene3D G3DSA:3.30.720.20 1 79 2.7E-33 T 11-10-2018 IPR038073 YkuJ-like superfamily AFK25_04810 b6415d0c5f3941e3e69b209d61ab0503 79 PIRSF PIRSF037356 1 79 6.5E-32 T 11-10-2018 IPR014904 Protein of unknown function DUF1797 AFK25_08530 e55154448b83afbc9c259a7592273401 482 Gene3D G3DSA:3.40.630.10 185 435 3.2E-50 T 11-10-2018 AFK25_08530 e55154448b83afbc9c259a7592273401 482 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 248 257 - T 11-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 AFK25_08530 e55154448b83afbc9c259a7592273401 482 SUPERFAMILY SSF53187 192 435 1.78E-47 T 11-10-2018 AFK25_08530 e55154448b83afbc9c259a7592273401 482 Pfam PF04389 Peptidase family M28 246 418 4.6E-13 T 11-10-2018 IPR007484 Peptidase M28 AFK25_06725 118899a1acb6b12cb8688b9aaf2bb27d 410 SMART SM00852 4 170 5.4E-40 T 11-10-2018 IPR001453 MoaB/Mog domain AFK25_06725 118899a1acb6b12cb8688b9aaf2bb27d 410 PIRSF PIRSF006728 1 410 2.4E-162 T 11-10-2018 IPR008135 Competence-induced protein CinA AFK25_06725 118899a1acb6b12cb8688b9aaf2bb27d 410 SUPERFAMILY SSF142433 250 409 6.93E-48 T 11-10-2018 IPR036653 CinA-like, C-terminal AFK25_06725 118899a1acb6b12cb8688b9aaf2bb27d 410 TIGRFAM TIGR00200 cinA_nterm: competence/damage-inducible protein CinA N-terminal domain 1 409 3.1E-155 T 11-10-2018 IPR008135 Competence-induced protein CinA AFK25_06725 118899a1acb6b12cb8688b9aaf2bb27d 410 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 1 163 3.3E-32 T 11-10-2018 IPR001453 MoaB/Mog domain AFK25_06725 118899a1acb6b12cb8688b9aaf2bb27d 410 Pfam PF02464 Competence-damaged protein 258 408 1.9E-50 T 11-10-2018 IPR008136 CinA, C-terminal AFK25_06725 118899a1acb6b12cb8688b9aaf2bb27d 410 Pfam PF00994 Probable molybdopterin binding domain 5 168 3.3E-34 T 11-10-2018 IPR001453 MoaB/Mog domain AFK25_06725 118899a1acb6b12cb8688b9aaf2bb27d 410 Gene3D G3DSA:3.90.950.20 253 410 2.0E-51 T 11-10-2018 IPR036653 CinA-like, C-terminal AFK25_06725 118899a1acb6b12cb8688b9aaf2bb27d 410 TIGRFAM TIGR00199 PncC_domain: amidohydrolase, PncC family 265 407 2.8E-39 T 11-10-2018 IPR008136 CinA, C-terminal AFK25_06725 118899a1acb6b12cb8688b9aaf2bb27d 410 Gene3D G3DSA:3.40.980.10 1 167 1.3E-50 T 11-10-2018 IPR036425 MoaB/Mog-like domain superfamily AFK25_06725 118899a1acb6b12cb8688b9aaf2bb27d 410 Hamap MF_00226_B Putative competence-damage inducible protein [cinA]. 1 410 166.7 T 11-10-2018 IPR008135 Competence-induced protein CinA AFK25_06725 118899a1acb6b12cb8688b9aaf2bb27d 410 SUPERFAMILY SSF53218 1 206 4.97E-41 T 11-10-2018 IPR036425 MoaB/Mog-like domain superfamily AFK25_07740 f9dac5160bf8ad2107cdc163286a796f 77 Pfam PF11122 Inner spore coat protein D 9 72 4.9E-20 T 11-10-2018 IPR020108 Spore coat protein CotD AFK25_07740 f9dac5160bf8ad2107cdc163286a796f 77 ProDom PD057197 SPORE COAT CAPSID D INNER D COTD SPORULATION 2 64 1.0E-15 T 11-10-2018 IPR020108 Spore coat protein CotD AFK25_03395 09fd5b5bd52fe55986b556c03533a8dd 312 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 10 150 1.7E-56 T 11-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 AFK25_03395 09fd5b5bd52fe55986b556c03533a8dd 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 137 148 5.0E-26 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFK25_03395 09fd5b5bd52fe55986b556c03533a8dd 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 277 300 5.0E-26 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFK25_03395 09fd5b5bd52fe55986b556c03533a8dd 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 274 5.0E-26 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFK25_03395 09fd5b5bd52fe55986b556c03533a8dd 312 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 55 74 5.0E-26 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFK25_03395 09fd5b5bd52fe55986b556c03533a8dd 312 Gene3D G3DSA:3.40.50.1370 10 139 1.3E-128 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFK25_03395 09fd5b5bd52fe55986b556c03533a8dd 312 PRINTS PR00102 Ornithine carbamoyltransferase signature 291 302 1.1E-29 T 11-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFK25_03395 09fd5b5bd52fe55986b556c03533a8dd 312 PRINTS PR00102 Ornithine carbamoyltransferase signature 53 67 1.1E-29 T 11-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFK25_03395 09fd5b5bd52fe55986b556c03533a8dd 312 PRINTS PR00102 Ornithine carbamoyltransferase signature 229 239 1.1E-29 T 11-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFK25_03395 09fd5b5bd52fe55986b556c03533a8dd 312 PRINTS PR00102 Ornithine carbamoyltransferase signature 86 99 1.1E-29 T 11-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFK25_03395 09fd5b5bd52fe55986b556c03533a8dd 312 PRINTS PR00102 Ornithine carbamoyltransferase signature 126 140 1.1E-29 T 11-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFK25_03395 09fd5b5bd52fe55986b556c03533a8dd 312 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 10 312 3.2E-135 T 11-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AFK25_03395 09fd5b5bd52fe55986b556c03533a8dd 312 SUPERFAMILY SSF53671 6 312 1.17E-111 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFK25_03395 09fd5b5bd52fe55986b556c03533a8dd 312 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 55 62 - T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFK25_03395 09fd5b5bd52fe55986b556c03533a8dd 312 Gene3D G3DSA:3.40.50.1370 140 308 1.3E-128 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFK25_03395 09fd5b5bd52fe55986b556c03533a8dd 312 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 9 312 84.002 T 11-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 AFK25_03395 09fd5b5bd52fe55986b556c03533a8dd 312 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 156 310 3.6E-58 T 11-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 AFK25_13035 f2dfbcf7502b68f48c59419d33c81ddf 269 Pfam PF01790 Prolipoprotein diacylglyceryl transferase 11 255 3.8E-80 T 11-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 AFK25_13035 f2dfbcf7502b68f48c59419d33c81ddf 269 ProSitePatterns PS01311 Prolipoprotein diacylglyceryl transferase signature. 136 148 - T 11-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 AFK25_13035 f2dfbcf7502b68f48c59419d33c81ddf 269 Hamap MF_01147 Prolipoprotein diacylglyceryl transferase [lgt]. 7 261 17.931 T 11-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 AFK25_13035 f2dfbcf7502b68f48c59419d33c81ddf 269 TIGRFAM TIGR00544 lgt: prolipoprotein diacylglyceryl transferase 6 256 7.6E-85 T 11-10-2018 IPR001640 Prolipoprotein diacylglyceryl transferase GO:0016020|GO:0016757|GO:0042158 AFK25_11580 64a5fc35a9e64562949bdea30bbc4ae1 271 SUPERFAMILY SSF81624 2 136 1.7E-42 T 11-10-2018 IPR035937 MutM-like, N-terminal AFK25_11580 64a5fc35a9e64562949bdea30bbc4ae1 271 Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain 1 116 9.8E-36 T 11-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AFK25_11580 64a5fc35a9e64562949bdea30bbc4ae1 271 SMART SM01232 131 223 1.6E-45 T 11-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 AFK25_11580 64a5fc35a9e64562949bdea30bbc4ae1 271 SUPERFAMILY SSF46946 130 219 2.62E-30 T 11-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AFK25_11580 64a5fc35a9e64562949bdea30bbc4ae1 271 ProSitePatterns PS01242 Zinc finger FPG-type signature. 246 270 - T 11-10-2018 IPR015887 DNA glycosylase/AP lyase, zinc finger domain, DNA-binding site GO:0003677|GO:0003906|GO:0006281|GO:0008270|GO:0016799 AFK25_11580 64a5fc35a9e64562949bdea30bbc4ae1 271 SMART SM00898 2 117 6.5E-49 T 11-10-2018 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain GO:0003684|GO:0003906|GO:0006284|GO:0008270|GO:0016799 AFK25_11580 64a5fc35a9e64562949bdea30bbc4ae1 271 Gene3D G3DSA:1.10.8.50 133 271 3.7E-51 T 11-10-2018 AFK25_11580 64a5fc35a9e64562949bdea30bbc4ae1 271 Gene3D G3DSA:3.20.190.10 1 130 1.1E-42 T 11-10-2018 IPR035937 MutM-like, N-terminal AFK25_11580 64a5fc35a9e64562949bdea30bbc4ae1 271 Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. 1 271 43.612 T 11-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 AFK25_11580 64a5fc35a9e64562949bdea30bbc4ae1 271 TIGRFAM TIGR00577 fpg: DNA-formamidopyrimidine glycosylase 1 270 1.7E-110 T 11-10-2018 IPR020629 Formamidopyrimidine-DNA glycosylase GO:0003906|GO:0006281|GO:0008270|GO:0008534 AFK25_11580 64a5fc35a9e64562949bdea30bbc4ae1 271 Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain 131 221 1.8E-32 T 11-10-2018 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding GO:0003684|GO:0003906|GO:0006289|GO:0008270|GO:0016799 AFK25_11580 64a5fc35a9e64562949bdea30bbc4ae1 271 SUPERFAMILY SSF57716 220 270 7.45E-17 T 11-10-2018 AFK25_11580 64a5fc35a9e64562949bdea30bbc4ae1 271 Pfam PF06827 Zinc finger found in FPG and IleRS 244 270 6.2E-9 T 11-10-2018 IPR010663 Zinc finger, FPG/IleRS-type Reactome: R-HSA-379726 AFK25_05015 68f8eefae06d0e52c66f59461f0ffef5 301 Gene3D G3DSA:1.10.357.140 29 185 5.1E-17 T 11-10-2018 AFK25_05015 68f8eefae06d0e52c66f59461f0ffef5 301 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 19 298 3.1E-93 T 11-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 AFK25_05015 68f8eefae06d0e52c66f59461f0ffef5 301 Pfam PF01040 UbiA prenyltransferase family 34 284 9.7E-57 T 11-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AFK25_05015 68f8eefae06d0e52c66f59461f0ffef5 301 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 17 300 18.253 T 11-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 AFK25_05015 68f8eefae06d0e52c66f59461f0ffef5 301 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 77 99 - T 11-10-2018 IPR030470 UbiA prenyltransferase conserved site AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 TIGRFAM TIGR02937 sigma70-ECF: RNA polymerase sigma factor, sigma-70 family 135 360 2.7E-39 T 11-10-2018 IPR014284 RNA polymerase sigma-70 like domain GO:0003700|GO:0006352|GO:0006355 AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 TIGRFAM TIGR02393 RpoD_Cterm: RNA polymerase sigma factor RpoD 135 371 1.5E-125 T 11-10-2018 IPR012760 RNA polymerase sigma factor RpoD, C-terminal GO:0003677|GO:0006352|GO:0006355|GO:0016987 AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 PRINTS PR00046 Major sigma-70 factor signature 187 195 3.1E-32 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 PRINTS PR00046 Major sigma-70 factor signature 347 358 3.1E-32 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 PRINTS PR00046 Major sigma-70 factor signature 163 176 3.1E-32 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 PRINTS PR00046 Major sigma-70 factor signature 332 347 3.1E-32 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 PRINTS PR00046 Major sigma-70 factor signature 311 323 3.1E-32 T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 Gene3D G3DSA:1.10.10.10 212 287 1.9E-36 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 ProSitePatterns PS00715 Sigma-70 factors family signature 1. 163 176 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 Hamap MF_00963 RNA polymerase sigma factor RpoD [rpoD]. 2 372 34.959 T 11-10-2018 IPR028630 RNA polymerase sigma factor RpoD GO:0006352|GO:0016987 AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 SUPERFAMILY SSF88659 212 285 5.23E-24 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 Gene3D G3DSA:1.10.10.10 300 372 2.8E-36 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 Pfam PF04539 Sigma-70 region 3 218 294 1.4E-33 T 11-10-2018 IPR007624 RNA polymerase sigma-70 region 3 GO:0003700|GO:0006352|GO:0006355 AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 Pfam PF04542 Sigma-70 region 2 139 208 3.9E-22 T 11-10-2018 IPR007627 RNA polymerase sigma-70 region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 SUPERFAMILY SSF88946 100 209 1.05E-55 T 11-10-2018 IPR013325 RNA polymerase sigma factor, region 2 GO:0003700|GO:0006352|GO:0006355 AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 ProSitePatterns PS00716 Sigma-70 factors family signature 2. 332 358 - T 11-10-2018 IPR000943 RNA polymerase sigma-70 GO:0003700|GO:0006352|GO:0006355 AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 Gene3D G3DSA:1.10.220.120 11 70 1.4E-12 T 11-10-2018 AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 Pfam PF00140 Sigma-70 factor, region 1.2 101 134 2.2E-20 T 11-10-2018 IPR009042 RNA polymerase sigma-70 region 1.2 GO:0003677|GO:0003700|GO:0006352|GO:0006355|GO:0016987 AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 Pfam PF03979 Sigma-70 factor, region 1.1 14 85 1.8E-18 T 11-10-2018 IPR007127 RNA polymerase sigma factor 70, region 1.1 GO:0003677|GO:0006355 AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 Pfam PF04545 Sigma-70, region 4 307 360 5.1E-20 T 11-10-2018 IPR007630 RNA polymerase sigma-70 region 4 GO:0003700|GO:0006352|GO:0006355 AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 Gene3D G3DSA:1.10.601.10 134 211 4.6E-51 T 11-10-2018 AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 Gene3D G3DSA:1.10.601.10 99 133 4.3E-13 T 11-10-2018 AFK25_10280 2d787d220f659ea29e5892f533f3996a 372 SUPERFAMILY SSF88659 269 370 2.43E-30 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFK25_12010 0bbcb0f6357bb88bdc9f05cf43612137 467 Gene3D G3DSA:3.40.630.10 15 465 8.1E-171 T 11-10-2018 AFK25_12010 0bbcb0f6357bb88bdc9f05cf43612137 467 SUPERFAMILY SSF53187 2 466 1.34E-68 T 11-10-2018 AFK25_12010 0bbcb0f6357bb88bdc9f05cf43612137 467 Gene3D G3DSA:3.30.70.360 186 381 8.1E-171 T 11-10-2018 AFK25_12010 0bbcb0f6357bb88bdc9f05cf43612137 467 TIGRFAM TIGR01887 dipeptidaselike: putative dipeptidase 15 462 1.2E-173 T 11-10-2018 IPR010964 Peptidase M20A, peptidase V-related GO:0008270|GO:0016805 AFK25_12010 0bbcb0f6357bb88bdc9f05cf43612137 467 Gene3D G3DSA:3.30.70.360 205 292 8.1E-171 T 11-10-2018 AFK25_12010 0bbcb0f6357bb88bdc9f05cf43612137 467 SUPERFAMILY SSF55031 186 378 4.64E-52 T 11-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain AFK25_12010 0bbcb0f6357bb88bdc9f05cf43612137 467 Pfam PF01546 Peptidase family M20/M25/M40 86 463 1.1E-31 T 11-10-2018 IPR002933 Peptidase M20 GO:0016787 AFK25_08720 6fc95287df0ea56ef24e511949110dae 223 Pfam PF07261 Replication initiation and membrane attachment 124 195 2.0E-27 T 11-10-2018 IPR006343 DnaD domain AFK25_08720 6fc95287df0ea56ef24e511949110dae 223 SUPERFAMILY SSF158499 123 188 2.09E-20 T 11-10-2018 IPR034829 DnaD-like domain superfamily AFK25_08720 6fc95287df0ea56ef24e511949110dae 223 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 122 193 4.3E-26 T 11-10-2018 IPR006343 DnaD domain AFK25_08720 6fc95287df0ea56ef24e511949110dae 223 Gene3D G3DSA:1.10.10.630 117 194 8.5E-34 T 11-10-2018 IPR034829 DnaD-like domain superfamily AFK25_08720 6fc95287df0ea56ef24e511949110dae 223 SUPERFAMILY SSF46785 4 119 3.61E-8 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_08720 6fc95287df0ea56ef24e511949110dae 223 Gene3D G3DSA:1.10.10.10 1 113 4.9E-38 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_10460 91cb1141a88fc237d80f6552098810d4 246 Pfam PF13649 Methyltransferase domain 39 134 1.6E-22 T 11-10-2018 AFK25_10460 91cb1141a88fc237d80f6552098810d4 246 SUPERFAMILY SSF53335 3 246 7.47E-56 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_10460 91cb1141a88fc237d80f6552098810d4 246 Gene3D G3DSA:2.20.25.110 142 205 5.8E-87 T 11-10-2018 AFK25_10460 91cb1141a88fc237d80f6552098810d4 246 Gene3D G3DSA:3.40.50.150 5 244 5.8E-87 T 11-10-2018 AFK25_00015 2bfaf91390b687c69780923853b64cbf 70 Pfam PF13275 S4 domain 4 68 1.5E-28 T 11-10-2018 AFK25_00015 2bfaf91390b687c69780923853b64cbf 70 TIGRFAM TIGR02988 YaaA_near_RecF: S4 domain protein YaaA 3 61 2.0E-30 T 11-10-2018 IPR014330 RNA-binding S4-related,YaaA AFK25_00015 2bfaf91390b687c69780923853b64cbf 70 SUPERFAMILY SSF55174 1 62 3.24E-19 T 11-10-2018 AFK25_00015 2bfaf91390b687c69780923853b64cbf 70 Gene3D G3DSA:3.10.290.10 1 65 2.3E-24 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFK25_09175 889f28b41b9ee2581a348c686b39b849 198 PIRSF PIRSF000709 8 156 1.1E-7 T 11-10-2018 AFK25_09175 889f28b41b9ee2581a348c686b39b849 198 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 10 167 1.5E-25 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFK25_09175 889f28b41b9ee2581a348c686b39b849 198 SMART SM00855 6 147 2.8E-5 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFK25_09175 889f28b41b9ee2581a348c686b39b849 198 Gene3D G3DSA:3.40.50.1240 6 192 2.2E-33 T 11-10-2018 IPR029033 Histidine phosphatase superfamily AFK25_09175 889f28b41b9ee2581a348c686b39b849 198 SUPERFAMILY SSF53254 7 180 9.85E-33 T 11-10-2018 IPR029033 Histidine phosphatase superfamily AFK25_08000 bcbb33e718735e7440bc0df7402881c6 546 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 154 179 4.1E-16 T 11-10-2018 AFK25_08000 bcbb33e718735e7440bc0df7402881c6 546 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 278 285 4.1E-16 T 11-10-2018 AFK25_08000 bcbb33e718735e7440bc0df7402881c6 546 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 237 251 4.1E-16 T 11-10-2018 AFK25_08000 bcbb33e718735e7440bc0df7402881c6 546 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 3 25 4.1E-16 T 11-10-2018 AFK25_08000 bcbb33e718735e7440bc0df7402881c6 546 SUPERFAMILY SSF51905 1 318 5.32E-46 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_08000 bcbb33e718735e7440bc0df7402881c6 546 SUPERFAMILY SSF55424 324 446 6.01E-34 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFK25_08000 bcbb33e718735e7440bc0df7402881c6 546 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 331 432 1.1E-15 T 11-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFK25_08000 bcbb33e718735e7440bc0df7402881c6 546 Gene3D G3DSA:3.50.50.60 115 440 9.4E-191 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_08000 bcbb33e718735e7440bc0df7402881c6 546 SMART SM00450 451 546 2.2E-14 T 11-10-2018 IPR001763 Rhodanese-like domain AFK25_08000 bcbb33e718735e7440bc0df7402881c6 546 Gene3D G3DSA:3.50.50.60 3 341 9.4E-191 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_08000 bcbb33e718735e7440bc0df7402881c6 546 TIGRFAM TIGR03385 CoA_CoA_reduc: CoA-disulfide reductase 3 440 1.4E-179 T 11-10-2018 IPR017758 Coenzyme A disulphide reductase GO:0003756|GO:0050451|GO:0050660|GO:0050661|GO:0055114 AFK25_08000 bcbb33e718735e7440bc0df7402881c6 546 Pfam PF00581 Rhodanese-like domain 461 543 1.2E-11 T 11-10-2018 IPR001763 Rhodanese-like domain AFK25_08000 bcbb33e718735e7440bc0df7402881c6 546 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 285 8.2E-64 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFK25_08000 bcbb33e718735e7440bc0df7402881c6 546 SUPERFAMILY SSF52821 434 543 8.64E-27 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_08000 bcbb33e718735e7440bc0df7402881c6 546 Gene3D G3DSA:3.40.250.10 450 545 3.4E-26 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_08000 bcbb33e718735e7440bc0df7402881c6 546 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 263 285 5.7E-26 T 11-10-2018 AFK25_08000 bcbb33e718735e7440bc0df7402881c6 546 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 154 172 5.7E-26 T 11-10-2018 AFK25_08000 bcbb33e718735e7440bc0df7402881c6 546 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 106 124 5.7E-26 T 11-10-2018 AFK25_08000 bcbb33e718735e7440bc0df7402881c6 546 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 236 252 5.7E-26 T 11-10-2018 AFK25_08000 bcbb33e718735e7440bc0df7402881c6 546 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.7E-26 T 11-10-2018 AFK25_08610 dac2764e2141daf89e6809502d21ea54 322 Pfam PF01032 FecCD transport family 12 317 1.3E-84 T 11-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AFK25_08610 dac2764e2141daf89e6809502d21ea54 322 Gene3D G3DSA:1.10.3470.10 2 321 1.3E-86 T 11-10-2018 IPR037294 ABC transporter, BtuC-like AFK25_08610 dac2764e2141daf89e6809502d21ea54 322 SUPERFAMILY SSF81345 4 317 4.18E-77 T 11-10-2018 IPR037294 ABC transporter, BtuC-like AFK25_12660 58eabb72e86039e03b96c4af55c5d7db 88 Pfam PF11256 Protein of unknown function (DUF3055) 6 85 1.1E-37 T 11-10-2018 IPR021415 Protein of unknown function DUF3055 AFK25_04205 6f22f1eee43a7182536043dcd05363df 366 SUPERFAMILY SSF51419 7 229 7.52E-28 T 11-10-2018 IPR029066 PLP-binding barrel AFK25_04205 6f22f1eee43a7182536043dcd05363df 366 Gene3D G3DSA:3.20.20.10 9 222 5.8E-27 T 11-10-2018 IPR029066 PLP-binding barrel AFK25_04205 6f22f1eee43a7182536043dcd05363df 366 Pfam PF01168 Alanine racemase, N-terminal domain 7 226 1.7E-25 T 11-10-2018 IPR001608 Alanine racemase, N-terminal KEGG: 00473+5.1.1.1|MetaCyc: PWY-7383 AFK25_05725 a180522f1c536e6ef867482d39367f5a 383 SUPERFAMILY SSF101801 299 381 1.31E-25 T 11-10-2018 IPR036429 SpoA-like superfamily AFK25_05725 a180522f1c536e6ef867482d39367f5a 383 SUPERFAMILY SSF103039 33 223 3.66E-50 T 11-10-2018 IPR028976 CheC-like superfamily AFK25_05725 a180522f1c536e6ef867482d39367f5a 383 Gene3D G3DSA:3.40.1550.10 33 230 2.4E-55 T 11-10-2018 IPR028976 CheC-like superfamily AFK25_05725 a180522f1c536e6ef867482d39367f5a 383 TIGRFAM TIGR02480 fliN: flagellar motor switch protein FliN 300 375 1.2E-31 T 11-10-2018 IPR012826 Flagellar motor switch FliN GO:0006935|GO:0009288|GO:0016020|GO:0071973 AFK25_05725 a180522f1c536e6ef867482d39367f5a 383 Pfam PF01052 Type III flagellar switch regulator (C-ring) FliN C-term 303 373 1.4E-25 T 11-10-2018 IPR001543 Surface presentation of antigen (SpoA) AFK25_05725 a180522f1c536e6ef867482d39367f5a 383 Gene3D G3DSA:2.30.330.10 291 383 2.3E-36 T 11-10-2018 IPR036429 SpoA-like superfamily AFK25_05725 a180522f1c536e6ef867482d39367f5a 383 PRINTS PR00956 Flagellar motor switch protein FliN signature 336 349 1.1E-29 T 11-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 AFK25_05725 a180522f1c536e6ef867482d39367f5a 383 PRINTS PR00956 Flagellar motor switch protein FliN signature 349 364 1.1E-29 T 11-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 AFK25_05725 a180522f1c536e6ef867482d39367f5a 383 PRINTS PR00956 Flagellar motor switch protein FliN signature 320 336 1.1E-29 T 11-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 AFK25_05725 a180522f1c536e6ef867482d39367f5a 383 PRINTS PR00956 Flagellar motor switch protein FliN signature 303 319 1.1E-29 T 11-10-2018 IPR001172 Flagellar motor switch FliN/Type III secretion HrcQb GO:0003774|GO:0006935|GO:0009425|GO:0071973 AFK25_05725 a180522f1c536e6ef867482d39367f5a 383 Pfam PF04509 CheC-like family 38 74 2.8E-13 T 11-10-2018 IPR007597 CheC-like protein GO:0016787 AFK25_05725 a180522f1c536e6ef867482d39367f5a 383 Pfam PF04509 CheC-like family 135 171 1.7E-15 T 11-10-2018 IPR007597 CheC-like protein GO:0016787 AFK25_02905 7027200c4072f33c682f71df839bc9f2 435 Gene3D G3DSA:3.40.190.10 162 428 4.0E-114 T 11-10-2018 AFK25_02905 7027200c4072f33c682f71df839bc9f2 435 Pfam PF01547 Bacterial extracellular solute-binding protein 55 349 1.5E-46 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFK25_02905 7027200c4072f33c682f71df839bc9f2 435 SUPERFAMILY SSF53850 49 412 7.77E-94 T 11-10-2018 AFK25_02905 7027200c4072f33c682f71df839bc9f2 435 Gene3D G3DSA:3.40.190.10 64 388 4.0E-114 T 11-10-2018 AFK25_02910 8061ec28a016479f5bac0211f27b70c2 431 SUPERFAMILY SSF161098 188 415 1.01E-62 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_02910 8061ec28a016479f5bac0211f27b70c2 431 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 219 422 4.7E-18 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_02910 8061ec28a016479f5bac0211f27b70c2 431 Gene3D G3DSA:1.10.3720.10 184 423 2.1E-71 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_05895 febba74d39fb09569bfca216bc6c8f48 92 Pfam PF04456 Protein of unknown function (DUF503) 2 86 6.9E-30 T 11-10-2018 IPR007546 Protein of unknown function DUF503 AFK25_05895 febba74d39fb09569bfca216bc6c8f48 92 SUPERFAMILY SSF103007 1 92 4.18E-29 T 11-10-2018 IPR036746 TT1725-like superfamily AFK25_05895 febba74d39fb09569bfca216bc6c8f48 92 Gene3D G3DSA:3.30.70.1120 1 92 4.6E-23 T 11-10-2018 IPR036746 TT1725-like superfamily AFK25_02635 682e6060ab15bc5b41d5198a887e939b 150 SUPERFAMILY SSF53155 4 73 9.81E-15 T 11-10-2018 IPR036631 Methylated DNA-protein cysteine methyltransferase domain superfamily GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AFK25_02635 682e6060ab15bc5b41d5198a887e939b 150 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 69 148 3.5E-38 T 11-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFK25_02635 682e6060ab15bc5b41d5198a887e939b 150 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 119 125 - T 11-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AFK25_02635 682e6060ab15bc5b41d5198a887e939b 150 Gene3D G3DSA:3.30.160.70 3 64 3.0E-9 T 11-10-2018 AFK25_02635 682e6060ab15bc5b41d5198a887e939b 150 Gene3D G3DSA:1.10.10.10 68 150 3.1E-39 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_02635 682e6060ab15bc5b41d5198a887e939b 150 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 7 149 36.934 T 11-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 AFK25_02635 682e6060ab15bc5b41d5198a887e939b 150 SUPERFAMILY SSF46767 68 148 4.71E-34 T 11-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 AFK25_02635 682e6060ab15bc5b41d5198a887e939b 150 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 70 148 2.1E-36 T 11-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AFK25_13285 5eeac2d377e082c9a4c9bc6ae47bd7e2 446 SMART SM00487 99 281 4.4E-13 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFK25_13285 5eeac2d377e082c9a4c9bc6ae47bd7e2 446 Gene3D G3DSA:3.40.50.300 104 268 1.1E-20 T 11-10-2018 AFK25_13285 5eeac2d377e082c9a4c9bc6ae47bd7e2 446 Pfam PF04851 Type III restriction enzyme, res subunit 102 250 1.6E-8 T 11-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFK25_13285 5eeac2d377e082c9a4c9bc6ae47bd7e2 446 Pfam PF00271 Helicase conserved C-terminal domain 305 405 2.7E-11 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_13285 5eeac2d377e082c9a4c9bc6ae47bd7e2 446 Gene3D G3DSA:3.40.50.300 287 444 1.3E-22 T 11-10-2018 AFK25_13285 5eeac2d377e082c9a4c9bc6ae47bd7e2 446 SUPERFAMILY SSF52540 118 416 5.1E-37 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_13285 5eeac2d377e082c9a4c9bc6ae47bd7e2 446 SMART SM00490 325 406 4.0E-10 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_09170 9f994ab2ef18670e03238e07ef171a53 141 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 17 137 5.7E-12 T 11-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 AFK25_09170 9f994ab2ef18670e03238e07ef171a53 141 Gene3D G3DSA:3.40.50.300 16 141 9.9E-11 T 11-10-2018 AFK25_09170 9f994ab2ef18670e03238e07ef171a53 141 SUPERFAMILY SSF52540 2 141 2.76E-14 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_13265 fffcd83231a6a0d55088c95bc3693b5e 145 Pfam PF03885 Protein of unknown function (DUF327) 15 144 2.8E-39 T 11-10-2018 IPR005585 Protein of unknown function DUF327 AFK25_13265 fffcd83231a6a0d55088c95bc3693b5e 145 Gene3D G3DSA:1.20.120.490 24 145 5.6E-38 T 11-10-2018 IPR024042 TM1646-like domain superfamily AFK25_13265 fffcd83231a6a0d55088c95bc3693b5e 145 SUPERFAMILY SSF158397 26 144 2.09E-34 T 11-10-2018 IPR024042 TM1646-like domain superfamily AFK25_04865 ecada9b0538f0837758d418091ba193b 325 SUPERFAMILY SSF52922 188 324 2.36E-42 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFK25_04865 ecada9b0538f0837758d418091ba193b 325 Pfam PF02780 Transketolase, C-terminal domain 194 311 3.3E-41 T 11-10-2018 IPR033248 Transketolase, C-terminal domain AFK25_04865 ecada9b0538f0837758d418091ba193b 325 Pfam PF02779 Transketolase, pyrimidine binding domain 3 178 2.5E-41 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFK25_04865 ecada9b0538f0837758d418091ba193b 325 Gene3D G3DSA:3.40.50.970 1 192 3.9E-83 T 11-10-2018 AFK25_04865 ecada9b0538f0837758d418091ba193b 325 SUPERFAMILY SSF52518 3 193 1.18E-68 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold AFK25_04865 ecada9b0538f0837758d418091ba193b 325 Gene3D G3DSA:3.40.50.920 193 325 1.1E-48 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFK25_04865 ecada9b0538f0837758d418091ba193b 325 SMART SM00861 4 179 4.3E-67 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFK25_00425 e25d42faccce81db476bcb817d6ec68d 333 PIRSF PIRSF006621 1 330 3.4E-107 T 11-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 AFK25_00425 e25d42faccce81db476bcb817d6ec68d 333 ProSitePatterns PS01136 Uncharacterized protein family UPF0034 signature. 96 114 - T 11-10-2018 IPR018517 tRNA-dihydrouridine synthase, conserved site GO:0008033|GO:0017150|GO:0050660|GO:0055114 AFK25_00425 e25d42faccce81db476bcb817d6ec68d 333 SUPERFAMILY SSF51395 11 322 8.61E-91 T 11-10-2018 AFK25_00425 e25d42faccce81db476bcb817d6ec68d 333 TIGRFAM TIGR00737 nifR3_yhdG: putative TIM-barrel protein, nifR3 family 4 322 1.9E-134 T 11-10-2018 IPR004652 tRNA-dihydrouridine synthase, TIM-barrel, NifR3 GO:0008033|GO:0016491|GO:0050660|GO:0055114 AFK25_00425 e25d42faccce81db476bcb817d6ec68d 333 Gene3D G3DSA:1.10.1200.80 253 330 3.9E-22 T 11-10-2018 IPR024036 tRNA-dihydrouridine synthase, putative, C-terminal GO:0016491|GO:0055114 AFK25_00425 e25d42faccce81db476bcb817d6ec68d 333 Gene3D G3DSA:3.20.20.70 7 249 1.4E-82 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_00425 e25d42faccce81db476bcb817d6ec68d 333 Pfam PF01207 Dihydrouridine synthase (Dus) 14 317 3.9E-109 T 11-10-2018 IPR001269 tRNA-dihydrouridine synthase GO:0008033|GO:0017150|GO:0050660|GO:0055114 AFK25_06250 c5c4106e086ee9a5b43978ff63974f9e 205 SUPERFAMILY SSF50475 11 177 2.5E-36 T 11-10-2018 AFK25_06250 c5c4106e086ee9a5b43978ff63974f9e 205 PIRSF PIRSF010372 1 203 1.5E-62 T 11-10-2018 IPR007396 Transcriptional regulator PAI 2-type AFK25_06250 c5c4106e086ee9a5b43978ff63974f9e 205 Gene3D G3DSA:2.30.110.10 1 202 3.8E-73 T 11-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFK25_06250 c5c4106e086ee9a5b43978ff63974f9e 205 Pfam PF04299 Putative FMN-binding domain 1 158 2.3E-51 T 11-10-2018 IPR007396 Transcriptional regulator PAI 2-type AFK25_10065 3977f25ef40d6928caff85e94999ade6 61 Pfam PF10958 Protein of unknown function (DUF2759) 10 59 7.1E-27 T 11-10-2018 IPR024490 Protein of unknown function DUF2759 AFK25_10065 3977f25ef40d6928caff85e94999ade6 61 ProDom PD052097 RELATED ALKALIPHILY YQGW MEMBRANE TRANSMEMBRANE SPANNING 18 58 5.0E-11 T 11-10-2018 IPR024490 Protein of unknown function DUF2759 AFK25_05990 57ab0de4b4a3d556dd8c1a335f98a29e 357 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 41 351 3.1E-94 T 11-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 AFK25_05990 57ab0de4b4a3d556dd8c1a335f98a29e 357 SUPERFAMILY SSF53822 55 271 1.44E-13 T 11-10-2018 IPR028082 Periplasmic binding protein-like I AFK25_05990 57ab0de4b4a3d556dd8c1a335f98a29e 357 Gene3D G3DSA:3.40.50.2300 147 347 2.8E-120 T 11-10-2018 AFK25_05990 57ab0de4b4a3d556dd8c1a335f98a29e 357 Gene3D G3DSA:3.40.50.2300 43 313 2.8E-120 T 11-10-2018 AFK25_07335 3f3770bc9b806002c954b65656739253 225 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 191 206 2.6E-6 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFK25_07335 3f3770bc9b806002c954b65656739253 225 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 175 191 2.6E-6 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFK25_07335 3f3770bc9b806002c954b65656739253 225 Pfam PF13545 Crp-like helix-turn-helix domain 151 221 1.6E-14 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFK25_07335 3f3770bc9b806002c954b65656739253 225 SMART SM00419 169 224 2.7E-5 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFK25_07335 3f3770bc9b806002c954b65656739253 225 Gene3D G3DSA:2.60.120.1460 16 223 3.4E-53 T 11-10-2018 AFK25_07335 3f3770bc9b806002c954b65656739253 225 SMART SM00100 12 133 1.1E-9 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain AFK25_07335 3f3770bc9b806002c954b65656739253 225 SUPERFAMILY SSF46785 147 208 4.54E-14 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_07335 3f3770bc9b806002c954b65656739253 225 SUPERFAMILY SSF51206 6 139 3.93E-30 T 11-10-2018 IPR018490 Cyclic nucleotide-binding-like AFK25_07335 3f3770bc9b806002c954b65656739253 225 Pfam PF00027 Cyclic nucleotide-binding domain 32 118 2.0E-14 T 11-10-2018 IPR000595 Cyclic nucleotide-binding domain AFK25_11810 22bf5e99812edd9c4ba1612c622eaef6 383 Gene3D G3DSA:3.90.1150.10 2 370 2.3E-138 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_11810 22bf5e99812edd9c4ba1612c622eaef6 383 Gene3D G3DSA:3.40.640.10 13 255 2.3E-138 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_11810 22bf5e99812edd9c4ba1612c622eaef6 383 Pfam PF00266 Aminotransferase class-V 2 362 1.1E-81 T 11-10-2018 IPR000192 Aminotransferase class V domain AFK25_11810 22bf5e99812edd9c4ba1612c622eaef6 383 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 192 211 - T 11-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site AFK25_11810 22bf5e99812edd9c4ba1612c622eaef6 383 PIRSF PIRSF005572 1 378 4.1E-123 T 11-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 AFK25_11810 22bf5e99812edd9c4ba1612c622eaef6 383 SUPERFAMILY SSF53383 1 374 9.41E-107 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_02680 0a2ac152a21961c6fcda30d7cc224ae5 231 Gene3D G3DSA:1.20.910.10 1 219 2.3E-66 T 11-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFK25_02680 0a2ac152a21961c6fcda30d7cc224ae5 231 SUPERFAMILY SSF48613 3 220 1.47E-74 T 11-10-2018 IPR016084 Haem oxygenase-like, multi-helical Reactome: R-HSA-189483|Reactome: R-HSA-917937 AFK25_02680 0a2ac152a21961c6fcda30d7cc224ae5 231 TIGRFAM TIGR04306 salvage_TenA: thiaminase II 11 214 9.5E-78 T 11-10-2018 IPR027574 Thiaminase II GO:0006772|GO:0050334 KEGG: 00730+3.5.99.2|MetaCyc: PWY-6899|MetaCyc: PWY-7356 AFK25_02680 0a2ac152a21961c6fcda30d7cc224ae5 231 Pfam PF03070 TENA/THI-4/PQQC family 9 214 1.1E-60 T 11-10-2018 IPR004305 Thiaminase-2/PQQC AFK25_11030 a3cd112cd79fe49349345aa083f8f297 413 SMART SM01208 297 371 3.6E-4 T 11-10-2018 IPR011098 G5 domain AFK25_11030 a3cd112cd79fe49349345aa083f8f297 413 Pfam PF04294 VanW like protein 219 287 7.9E-10 T 11-10-2018 IPR007391 Vancomycin resistance VanW AFK25_11030 a3cd112cd79fe49349345aa083f8f297 413 Gene3D G3DSA:2.20.230.10 298 370 1.1E-5 T 11-10-2018 AFK25_13020 f386f32ed78a711fc21e2143389bc7bd 162 Pfam PF14602 Hexapeptide repeat of succinyl-transferase 107 139 6.4E-11 T 11-10-2018 IPR001451 Hexapeptide repeat AFK25_13020 f386f32ed78a711fc21e2143389bc7bd 162 Gene3D G3DSA:2.160.10.10 3 162 2.2E-31 T 11-10-2018 AFK25_13020 f386f32ed78a711fc21e2143389bc7bd 162 SUPERFAMILY SSF51161 7 159 1.94E-37 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily AFK25_05375 74d54ab5900e1c61bcf037c0e72956d7 204 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 204 29.486 T 11-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFK25_05375 74d54ab5900e1c61bcf037c0e72956d7 204 Gene3D G3DSA:3.40.50.2020 1 203 7.4E-64 T 11-10-2018 AFK25_05375 74d54ab5900e1c61bcf037c0e72956d7 204 Pfam PF00156 Phosphoribosyl transferase domain 43 174 4.7E-19 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFK25_05375 74d54ab5900e1c61bcf037c0e72956d7 204 SUPERFAMILY SSF53271 2 198 5.24E-53 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like AFK25_05375 74d54ab5900e1c61bcf037c0e72956d7 204 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 9 177 3.0E-50 T 11-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFK25_07270 83376d1cf5adb2eb16d9b4adb63e03a1 87 Gene3D G3DSA:1.20.58.1000 2 86 8.0E-23 T 11-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily AFK25_07270 83376d1cf5adb2eb16d9b4adb63e03a1 87 Pfam PF02583 Metal-sensitive transcriptional repressor 5 84 3.5E-23 T 11-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 AFK25_04125 e6467c5985bfa23eaac497dd6f0118de 256 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 138 166 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFK25_04125 e6467c5985bfa23eaac497dd6f0118de 256 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 254 1.5E-65 T 11-10-2018 AFK25_04125 e6467c5985bfa23eaac497dd6f0118de 256 Gene3D G3DSA:3.40.50.720 1 256 1.6E-81 T 11-10-2018 AFK25_04125 e6467c5985bfa23eaac497dd6f0118de 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 172 189 2.0E-39 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04125 e6467c5985bfa23eaac497dd6f0118de 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 151 170 2.0E-39 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04125 e6467c5985bfa23eaac497dd6f0118de 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 125 141 2.0E-39 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04125 e6467c5985bfa23eaac497dd6f0118de 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.0E-39 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04125 e6467c5985bfa23eaac497dd6f0118de 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 217 237 2.0E-39 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04125 e6467c5985bfa23eaac497dd6f0118de 256 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 2.0E-39 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04125 e6467c5985bfa23eaac497dd6f0118de 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 151 170 1.0E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04125 e6467c5985bfa23eaac497dd6f0118de 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 1.0E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04125 e6467c5985bfa23eaac497dd6f0118de 256 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 131 139 1.0E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_04125 e6467c5985bfa23eaac497dd6f0118de 256 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 5 182 0.0059 T 11-10-2018 AFK25_04125 e6467c5985bfa23eaac497dd6f0118de 256 SUPERFAMILY SSF51735 3 255 3.29E-82 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_04125 e6467c5985bfa23eaac497dd6f0118de 256 TIGRFAM TIGR01963 PHB_DH: 3-hydroxybutyrate dehydrogenase 5 256 3.0E-106 T 11-10-2018 IPR011294 3-hydroxybutyrate dehydrogenase GO:0003858|GO:0055114 AFK25_06525 9fc8f9d6030f51793102a64629c50cab 284 SUPERFAMILY SSF53850 10 281 1.8E-72 T 11-10-2018 AFK25_06525 9fc8f9d6030f51793102a64629c50cab 284 SMART SM00062 57 281 1.1E-89 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFK25_06525 9fc8f9d6030f51793102a64629c50cab 284 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 58 280 3.5E-62 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFK25_06525 9fc8f9d6030f51793102a64629c50cab 284 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 81 94 - T 11-10-2018 IPR018313 Solute-binding protein family 3, conserved site AFK25_06525 9fc8f9d6030f51793102a64629c50cab 284 Gene3D G3DSA:3.40.190.10 58 277 3.7E-84 T 11-10-2018 AFK25_06525 9fc8f9d6030f51793102a64629c50cab 284 SMART SM00079 57 280 1.3E-5 T 11-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 AFK25_06525 9fc8f9d6030f51793102a64629c50cab 284 Gene3D G3DSA:3.40.190.10 145 243 3.7E-84 T 11-10-2018 AFK25_07600 fb730c7a801f585523969eceea89bca6 234 Gene3D G3DSA:3.40.50.1580 1 234 2.4E-72 T 11-10-2018 AFK25_07600 fb730c7a801f585523969eceea89bca6 234 Pfam PF01048 Phosphorylase superfamily 16 222 1.0E-40 T 11-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 AFK25_07600 fb730c7a801f585523969eceea89bca6 234 TIGRFAM TIGR00107 deoD: purine nucleoside phosphorylase 4 231 8.7E-108 T 11-10-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 AFK25_07600 fb730c7a801f585523969eceea89bca6 234 SUPERFAMILY SSF53167 2 232 7.59E-90 T 11-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 AFK25_07600 fb730c7a801f585523969eceea89bca6 234 Hamap MF_01627 Purine nucleoside phosphorylase DeoD-type [deoD]. 1 233 47.573 T 11-10-2018 IPR004402 Purine nucleoside phosphorylase DeoD-type GO:0004731|GO:0006139 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1 AFK25_07600 fb730c7a801f585523969eceea89bca6 234 ProSitePatterns PS01232 Purine and other phosphorylases family 1 signature. 61 76 - T 11-10-2018 IPR018016 Nucleoside phosphorylase, conserved site GO:0016763 KEGG: 00230+2.4.2.1|KEGG: 00240+2.4.2.1|KEGG: 00760+2.4.2.1|MetaCyc: PWY-4202|MetaCyc: PWY-5532|MetaCyc: PWY-5695|MetaCyc: PWY-6608|MetaCyc: PWY-6609|MetaCyc: PWY-6611|MetaCyc: PWY-6620|MetaCyc: PWY-6627|MetaCyc: PWY-6644|MetaCyc: PWY-7179|MetaCyc: PWY-7179-1|Reactome: R-HSA-73614|Reactome: R-HSA-73621 AFK25_06230 8f2fb9ae79fb883c32f91a618c86d44c 128 Pfam PF04134 Protein of unknown function, DUF393 4 112 2.3E-37 T 11-10-2018 IPR007263 Protein of unknown function DUF393 AFK25_09275 f3a31023c30960576be993ed824fef70 379 Pfam PF07282 Putative transposase DNA-binding domain 309 375 4.2E-23 T 11-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFK25_09275 f3a31023c30960576be993ed824fef70 379 Pfam PF12323 Helix-turn-helix domain 1 45 1.6E-13 T 11-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain AFK25_09275 f3a31023c30960576be993ed824fef70 379 Pfam PF01385 Probable transposase 166 294 1.5E-12 T 11-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 AFK25_09275 f3a31023c30960576be993ed824fef70 379 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 262 334 1.2E-12 T 11-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFK25_09765 da61061747497cd7ccdcc5ff736c96e3 366 Pfam PF00871 Acetokinase family 8 345 4.3E-76 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFK25_09765 da61061747497cd7ccdcc5ff736c96e3 366 PIRSF PIRSF036458 4 359 4.4E-179 T 11-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 AFK25_09765 da61061747497cd7ccdcc5ff736c96e3 366 Gene3D G3DSA:3.30.420.40 140 335 3.5E-163 T 11-10-2018 AFK25_09765 da61061747497cd7ccdcc5ff736c96e3 366 SUPERFAMILY SSF53067 6 175 4.75E-73 T 11-10-2018 AFK25_09765 da61061747497cd7ccdcc5ff736c96e3 366 TIGRFAM TIGR02707 butyr_kinase: butyrate kinase 7 357 6.3E-178 T 11-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 AFK25_09765 da61061747497cd7ccdcc5ff736c96e3 366 PRINTS PR00471 Acetate kinase family signature 300 316 2.2E-16 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFK25_09765 da61061747497cd7ccdcc5ff736c96e3 366 PRINTS PR00471 Acetate kinase family signature 182 203 2.2E-16 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFK25_09765 da61061747497cd7ccdcc5ff736c96e3 366 PRINTS PR00471 Acetate kinase family signature 277 290 2.2E-16 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFK25_09765 da61061747497cd7ccdcc5ff736c96e3 366 PRINTS PR00471 Acetate kinase family signature 8 19 2.2E-16 T 11-10-2018 IPR000890 Aliphatic acid kinase, short-chain GO:0005622|GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFK25_09765 da61061747497cd7ccdcc5ff736c96e3 366 SUPERFAMILY SSF53067 119 351 1.89E-58 T 11-10-2018 AFK25_09765 da61061747497cd7ccdcc5ff736c96e3 366 ProSitePatterns PS01075 Acetate and butyrate kinases family signature 1. 8 19 - T 11-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFK25_09765 da61061747497cd7ccdcc5ff736c96e3 366 Gene3D G3DSA:3.30.420.40 7 358 3.5E-163 T 11-10-2018 AFK25_09765 da61061747497cd7ccdcc5ff736c96e3 366 ProSitePatterns PS01076 Acetate and butyrate kinases family signature 2. 182 199 - T 11-10-2018 IPR023865 Aliphatic acid kinase, short-chain, conserved site GO:0016301|GO:0016310|GO:0016774 KEGG: 00430+2.7.2.1|KEGG: 00620+2.7.2.1|KEGG: 00640+2.7.2.1|KEGG: 00680+2.7.2.1|KEGG: 00720+2.7.2.1|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497 AFK25_09765 da61061747497cd7ccdcc5ff736c96e3 366 Hamap MF_00542 Probable butyrate kinase [buk]. 1 366 177.241 T 11-10-2018 IPR011245 Butyrate kinase GO:0005524|GO:0005737|GO:0016310|GO:0047761 KEGG: 00650+2.7.2.7 AFK25_00990 66e42baaf078b7b99c3cfdabec3b201a 539 Pfam PF13722 5TM C-terminal transporter carbon starvation CstA 376 488 3.2E-33 T 11-10-2018 IPR025299 CstA, C-terminal domain AFK25_00990 66e42baaf078b7b99c3cfdabec3b201a 539 Pfam PF02554 Carbon starvation protein CstA 2 349 1.2E-127 T 11-10-2018 IPR003706 CstA, N-terminal domain GO:0009267|GO:0016020 AFK25_13980 af24d77d393ac04e101cff02b928016c 172 Gene3D G3DSA:3.40.50.10490 1 172 9.6E-58 T 11-10-2018 AFK25_13980 af24d77d393ac04e101cff02b928016c 172 Pfam PF10740 Domain of unknown function (DUF2529) 1 168 1.2E-64 T 11-10-2018 IPR019676 Domain of unknown function (DUF2529) AFK25_13980 af24d77d393ac04e101cff02b928016c 172 SUPERFAMILY SSF53697 3 163 2.0E-9 T 11-10-2018 AFK25_07965 e5cbc415c22fe0049e01f1c37a3aee83 410 SUPERFAMILY SSF46689 304 354 5.82E-9 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_07965 e5cbc415c22fe0049e01f1c37a3aee83 410 SUPERFAMILY SSF46689 356 406 2.73E-14 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_07965 e5cbc415c22fe0049e01f1c37a3aee83 410 Pfam PF12833 Helix-turn-helix domain 327 404 4.0E-24 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFK25_07965 e5cbc415c22fe0049e01f1c37a3aee83 410 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 372 387 1.7E-5 T 11-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFK25_07965 e5cbc415c22fe0049e01f1c37a3aee83 410 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 387 403 1.7E-5 T 11-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFK25_07965 e5cbc415c22fe0049e01f1c37a3aee83 410 SMART SM00448 2 116 2.3E-25 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_07965 e5cbc415c22fe0049e01f1c37a3aee83 410 Gene3D G3DSA:1.10.10.60 302 353 6.6E-19 T 11-10-2018 AFK25_07965 e5cbc415c22fe0049e01f1c37a3aee83 410 Gene3D G3DSA:1.10.10.60 354 408 1.6E-21 T 11-10-2018 AFK25_07965 e5cbc415c22fe0049e01f1c37a3aee83 410 Gene3D G3DSA:3.40.50.2300 2 150 3.9E-33 T 11-10-2018 AFK25_07965 e5cbc415c22fe0049e01f1c37a3aee83 410 ProSitePatterns PS00041 Bacterial regulatory proteins, araC family signature. 357 399 - T 11-10-2018 IPR018062 HTH domain AraC-type, conserved site GO:0003700|GO:0006355|GO:0043565 AFK25_07965 e5cbc415c22fe0049e01f1c37a3aee83 410 Pfam PF00072 Response regulator receiver domain 5 116 2.6E-25 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_07965 e5cbc415c22fe0049e01f1c37a3aee83 410 SUPERFAMILY SSF52172 1 156 4.98E-32 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_07965 e5cbc415c22fe0049e01f1c37a3aee83 410 SMART SM00342 320 403 5.3E-37 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFK25_04590 f0a509374a138719ad58ad32d34e7df3 787 TIGRFAM TIGR00940 2a6301s01: monovalent cation:proton antiporter 3 786 0.0 T 11-10-2018 IPR005663 Monovalent cation proton antiporter subunit A GO:0015077|GO:0030004 AFK25_04590 f0a509374a138719ad58ad32d34e7df3 787 Pfam PF13244 Domain of unknown function (DUF4040) 624 688 1.4E-21 T 11-10-2018 IPR025383 Domain of unknown function DUF4040 AFK25_04590 f0a509374a138719ad58ad32d34e7df3 787 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 56 109 5.9E-13 T 11-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_04590 f0a509374a138719ad58ad32d34e7df3 787 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 72 92 3.2E-10 T 11-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFK25_04590 f0a509374a138719ad58ad32d34e7df3 787 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 421 443 3.2E-10 T 11-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFK25_04590 f0a509374a138719ad58ad32d34e7df3 787 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 250 272 3.2E-10 T 11-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFK25_04590 f0a509374a138719ad58ad32d34e7df3 787 PRINTS PR01435 NADH-plastoquinone oxidoreductase chain 5 signature 484 505 3.2E-10 T 11-10-2018 IPR018393 NADH-plastoquinone oxidoreductase, chain 5 subgroup GO:0008137|GO:0042773|GO:0055114 AFK25_04590 f0a509374a138719ad58ad32d34e7df3 787 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 99 119 3.7E-44 T 11-10-2018 AFK25_04590 f0a509374a138719ad58ad32d34e7df3 787 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 300 312 3.7E-44 T 11-10-2018 AFK25_04590 f0a509374a138719ad58ad32d34e7df3 787 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 422 441 3.7E-44 T 11-10-2018 AFK25_04590 f0a509374a138719ad58ad32d34e7df3 787 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 232 258 3.7E-44 T 11-10-2018 AFK25_04590 f0a509374a138719ad58ad32d34e7df3 787 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 210 231 3.7E-44 T 11-10-2018 AFK25_04590 f0a509374a138719ad58ad32d34e7df3 787 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 70 95 3.7E-44 T 11-10-2018 AFK25_04590 f0a509374a138719ad58ad32d34e7df3 787 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 146 167 3.7E-44 T 11-10-2018 AFK25_04590 f0a509374a138719ad58ad32d34e7df3 787 Pfam PF00361 Proton-conducting membrane transporter 122 416 5.7E-63 T 11-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_08540 1db961597db666fcd76158711055ff9b 640 Pfam PF13245 AAA domain 240 405 7.6E-13 T 11-10-2018 AFK25_08540 1db961597db666fcd76158711055ff9b 640 Gene3D G3DSA:3.40.50.300 427 638 1.9E-35 T 11-10-2018 AFK25_08540 1db961597db666fcd76158711055ff9b 640 Pfam PF13361 UvrD-like helicase C-terminal domain 424 540 3.6E-9 T 11-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFK25_08540 1db961597db666fcd76158711055ff9b 640 Gene3D G3DSA:3.40.50.300 229 422 1.7E-23 T 11-10-2018 AFK25_08540 1db961597db666fcd76158711055ff9b 640 Pfam PF13361 UvrD-like helicase C-terminal domain 548 612 6.4E-12 T 11-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFK25_08540 1db961597db666fcd76158711055ff9b 640 SUPERFAMILY SSF52540 235 629 4.58E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_08540 1db961597db666fcd76158711055ff9b 640 Pfam PF08378 Nuclease-related domain 14 110 1.2E-10 T 11-10-2018 IPR011528 Nuclease-related domain, NERD AFK25_01650 32b6dce0281328869382a79d89c634fa 361 Gene3D G3DSA:3.90.340.10 10 353 1.3E-156 T 11-10-2018 AFK25_01650 32b6dce0281328869382a79d89c634fa 361 ProSitePatterns PS60001 Nitric oxide synthase (NOS) signature. 69 76 - T 11-10-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 AFK25_01650 32b6dce0281328869382a79d89c634fa 361 PIRSF PIRSF037219 6 361 7.5E-195 T 11-10-2018 IPR017142 Nitric oxide synthase, oxygenase subunit GO:0004517|GO:0006809|GO:0020037 KEGG: 00220+1.14.14.47|KEGG: 00330+1.14.14.47 AFK25_01650 32b6dce0281328869382a79d89c634fa 361 Gene3D G3DSA:3.90.440.10 86 191 1.3E-156 T 11-10-2018 AFK25_01650 32b6dce0281328869382a79d89c634fa 361 Gene3D G3DSA:3.90.1230.10 192 298 1.3E-156 T 11-10-2018 AFK25_01650 32b6dce0281328869382a79d89c634fa 361 Pfam PF02898 Nitric oxide synthase, oxygenase domain 9 360 9.7E-178 T 11-10-2018 IPR004030 Nitric oxide synthase, N-terminal GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 AFK25_01650 32b6dce0281328869382a79d89c634fa 361 SUPERFAMILY SSF56512 9 360 1.57E-173 T 11-10-2018 IPR036119 Nitric oxide synthase, N-terminal domain superfamily GO:0004517|GO:0006809|GO:0055114 Reactome: R-HSA-1222556|Reactome: R-HSA-392154 AFK25_07735 01c15f2acba6cd6fe0b044b5e59e863f 98 Pfam PF05103 DivIVA protein 8 69 4.6E-18 T 11-10-2018 IPR007793 DivIVA family AFK25_07735 01c15f2acba6cd6fe0b044b5e59e863f 98 Hamap MF_02011 Cell cycle protein GpsB [gpsB]. 3 94 23.96 T 11-10-2018 IPR011229 Cell cycle protein GpsB AFK25_07735 01c15f2acba6cd6fe0b044b5e59e863f 98 TIGRFAM TIGR03544 DivI1A_domain: DivIVA domain 8 41 1.9E-16 T 11-10-2018 IPR019933 DivIVA domain AFK25_07735 01c15f2acba6cd6fe0b044b5e59e863f 98 PIRSF PIRSF029938 1 98 2.6E-38 T 11-10-2018 IPR011229 Cell cycle protein GpsB AFK25_03000 90520af32428b98a2015e9eefa1ccbac 406 Pfam PF00563 EAL domain 49 188 2.2E-13 T 11-10-2018 IPR001633 EAL domain AFK25_03000 90520af32428b98a2015e9eefa1ccbac 406 Gene3D G3DSA:3.20.20.450 39 190 2.3E-17 T 11-10-2018 IPR035919 EAL domain superfamily AFK25_03000 90520af32428b98a2015e9eefa1ccbac 406 PIRSF PIRSF003180 1 403 2.5E-118 T 11-10-2018 IPR014408 Signal transduction c-di-GMP phosphodiesterase, EAL/HD-GYP domain-containing AFK25_03000 90520af32428b98a2015e9eefa1ccbac 406 SMART SM00052 2 193 0.0011 T 11-10-2018 IPR001633 EAL domain AFK25_03000 90520af32428b98a2015e9eefa1ccbac 406 Pfam PF08668 HDOD domain 205 320 1.7E-13 T 11-10-2018 IPR013976 Metal-dependent hydrolase HDOD AFK25_03000 90520af32428b98a2015e9eefa1ccbac 406 SUPERFAMILY SSF141868 3 193 6.93E-30 T 11-10-2018 IPR035919 EAL domain superfamily AFK25_03000 90520af32428b98a2015e9eefa1ccbac 406 Gene3D G3DSA:1.10.3210.10 191 346 7.5E-21 T 11-10-2018 AFK25_03000 90520af32428b98a2015e9eefa1ccbac 406 SUPERFAMILY SSF109604 179 399 4.08E-35 T 11-10-2018 AFK25_02845 b0108fda57489305da6b585e97b33f00 139 Pfam PF01230 HIT domain 12 106 3.2E-26 T 11-10-2018 IPR001310 Histidine triad (HIT) protein AFK25_02845 b0108fda57489305da6b585e97b33f00 139 Gene3D G3DSA:1.20.5.1170 114 137 1.9E-8 T 11-10-2018 AFK25_02845 b0108fda57489305da6b585e97b33f00 139 SUPERFAMILY SSF54197 2 137 2.27E-46 T 11-10-2018 IPR036265 HIT-like superfamily AFK25_02845 b0108fda57489305da6b585e97b33f00 139 Gene3D G3DSA:3.30.428.10 1 112 8.8E-40 T 11-10-2018 IPR036265 HIT-like superfamily AFK25_02845 b0108fda57489305da6b585e97b33f00 139 PRINTS PR00332 Histidine triad family signature 93 103 2.4E-17 T 11-10-2018 IPR001310 Histidine triad (HIT) protein AFK25_02845 b0108fda57489305da6b585e97b33f00 139 PRINTS PR00332 Histidine triad family signature 5 21 2.4E-17 T 11-10-2018 IPR001310 Histidine triad (HIT) protein AFK25_02845 b0108fda57489305da6b585e97b33f00 139 PRINTS PR00332 Histidine triad family signature 26 44 2.4E-17 T 11-10-2018 IPR001310 Histidine triad (HIT) protein AFK25_02845 b0108fda57489305da6b585e97b33f00 139 ProSitePatterns PS00892 HIT domain signature. 86 104 - T 11-10-2018 IPR019808 Histidine triad, conserved site AFK25_14395 0cbdf71a248b991f5aa357b1b7e5281b 867 SUPERFAMILY SSF56796 455 866 1.24E-130 T 11-10-2018 AFK25_14395 0cbdf71a248b991f5aa357b1b7e5281b 867 Pfam PF00171 Aldehyde dehydrogenase family 12 277 3.0E-21 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFK25_14395 0cbdf71a248b991f5aa357b1b7e5281b 867 Gene3D G3DSA:3.40.50.1970 457 649 1.8E-67 T 11-10-2018 AFK25_14395 0cbdf71a248b991f5aa357b1b7e5281b 867 Gene3D G3DSA:3.40.309.10 227 412 4.5E-187 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFK25_14395 0cbdf71a248b991f5aa357b1b7e5281b 867 Gene3D G3DSA:3.40.605.10 19 450 4.5E-187 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFK25_14395 0cbdf71a248b991f5aa357b1b7e5281b 867 SUPERFAMILY SSF53720 17 460 1.31E-82 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFK25_14395 0cbdf71a248b991f5aa357b1b7e5281b 867 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 638 666 - T 11-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 AFK25_14395 0cbdf71a248b991f5aa357b1b7e5281b 867 PIRSF PIRSF000111 1 867 0.0 T 11-10-2018 IPR012079 Bifunctional aldehyde-alcohol dehydrogenase GO:0004022|GO:0006066|GO:0008774|GO:0015976|GO:0055114 KEGG: 00010+1.1.1.1|KEGG: 00071+1.1.1.1|KEGG: 00260+1.1.1.1|KEGG: 00350+1.1.1.1|KEGG: 00592+1.1.1.1|KEGG: 00625+1.1.1.1|KEGG: 00626+1.1.1.1|KEGG: 00830+1.1.1.1|KEGG: 00980+1.1.1.1|KEGG: 00982+1.1.1.1|MetaCyc: PWY-3162|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5079|MetaCyc: PWY-5082|MetaCyc: PWY-5480|MetaCyc: PWY-5486|MetaCyc: PWY-5751|MetaCyc: PWY-6313|MetaCyc: PWY-6333|MetaCyc: PWY-6342|MetaCyc: PWY-6587|MetaCyc: PWY-6802|MetaCyc: PWY-6871|MetaCyc: PWY-7013|MetaCyc: PWY-7111|MetaCyc: PWY-7118|MetaCyc: PWY-7396 AFK25_14395 0cbdf71a248b991f5aa357b1b7e5281b 867 Gene3D G3DSA:1.20.1090.10 650 867 7.3E-78 T 11-10-2018 AFK25_14395 0cbdf71a248b991f5aa357b1b7e5281b 867 Pfam PF00465 Iron-containing alcohol dehydrogenase 464 852 1.6E-126 T 11-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 AFK25_11465 e53b7c0969a22f1bc6c4915bdcd169d5 647 Pfam PF08532 Beta-galactosidase trimerisation domain 392 598 6.4E-46 T 11-10-2018 IPR013738 Beta-galactosidase trimerisation GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 AFK25_11465 e53b7c0969a22f1bc6c4915bdcd169d5 647 PIRSF PIRSF001084 1 635 8.1E-178 T 11-10-2018 IPR003476 Glycoside hydrolase, family 42 GO:0004565|GO:0005975 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 AFK25_11465 e53b7c0969a22f1bc6c4915bdcd169d5 647 Gene3D G3DSA:2.60.40.1180 605 643 5.9E-7 T 11-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFK25_11465 e53b7c0969a22f1bc6c4915bdcd169d5 647 SUPERFAMILY SSF51445 3 380 1.91E-100 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily AFK25_11465 e53b7c0969a22f1bc6c4915bdcd169d5 647 Gene3D G3DSA:3.40.50.880 390 601 4.8E-51 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_11465 e53b7c0969a22f1bc6c4915bdcd169d5 647 SUPERFAMILY SSF52317 389 598 2.27E-44 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_11465 e53b7c0969a22f1bc6c4915bdcd169d5 647 Gene3D G3DSA:3.20.20.80 1 387 4.8E-121 T 11-10-2018 AFK25_11465 e53b7c0969a22f1bc6c4915bdcd169d5 647 Pfam PF02449 Beta-galactosidase 6 379 2.3E-120 T 11-10-2018 IPR013529 Glycoside hydrolase, family 42, N-terminal GO:0004565|GO:0005975|GO:0009341 KEGG: 00052+3.2.1.23|KEGG: 00511+3.2.1.23|KEGG: 00531+3.2.1.23|KEGG: 00600+3.2.1.23|KEGG: 00604+3.2.1.23|MetaCyc: PWY-6807 AFK25_10405 049736a50eea1e393c88347852433009 101 Pfam PF12438 Protein of unknown function (DUF3679) 8 57 2.8E-22 T 11-10-2018 IPR020534 Uncharacterised protein family YqxA AFK25_10405 049736a50eea1e393c88347852433009 101 ProDom PD072942 YQXA ORF79 1 99 2.0E-16 T 11-10-2018 IPR020534 Uncharacterised protein family YqxA AFK25_05085 cf0dd34ce83b8a8e2e443e1be25e36ef 108 Pfam PF14071 Putative coat protein 4 108 2.6E-32 T 11-10-2018 IPR025953 Putative coat protein YlbD AFK25_03715 99ff4023fecbb65fc383909cee275eba 369 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 246 319 4.4E-10 T 11-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFK25_03715 99ff4023fecbb65fc383909cee275eba 369 Pfam PF07282 Putative transposase DNA-binding domain 292 360 6.2E-24 T 11-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFK25_03715 99ff4023fecbb65fc383909cee275eba 369 Pfam PF12323 Helix-turn-helix domain 1 44 1.8E-21 T 11-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain AFK25_03715 99ff4023fecbb65fc383909cee275eba 369 Pfam PF01385 Probable transposase 166 278 3.4E-29 T 11-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 AFK25_00770 c39280f9393a2a2cf033ed79831cfe68 144 PIRSF PIRSF002181 1 142 1.1E-51 T 11-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AFK25_00770 c39280f9393a2a2cf033ed79831cfe68 144 SUPERFAMILY SSF52161 4 142 4.06E-63 T 11-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 AFK25_00770 c39280f9393a2a2cf033ed79831cfe68 144 TIGRFAM TIGR01066 rplM_bact: ribosomal protein uL13 4 141 1.4E-66 T 11-10-2018 IPR005823 Ribosomal protein L13, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00770 c39280f9393a2a2cf033ed79831cfe68 144 Pfam PF00572 Ribosomal protein L13 14 138 7.4E-59 T 11-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AFK25_00770 c39280f9393a2a2cf033ed79831cfe68 144 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 15 143 29.691 T 11-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AFK25_00770 c39280f9393a2a2cf033ed79831cfe68 144 Gene3D G3DSA:3.90.1180.10 1 142 1.4E-64 T 11-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 AFK25_00770 c39280f9393a2a2cf033ed79831cfe68 144 ProSitePatterns PS00783 Ribosomal protein L13 signature. 105 127 - T 11-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 AFK25_07090 ee7744731ccd67ae93eae0fac05ac691 121 Pfam PF01986 Domain of unknown function DUF123 31 118 1.9E-22 T 11-10-2018 IPR002837 Protein of unknown function DUF123 AFK25_03175 c04051bf4f170241d4808bb569c6e619 282 SUPERFAMILY SSF46689 229 277 1.57E-13 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_03175 c04051bf4f170241d4808bb569c6e619 282 Gene3D G3DSA:1.10.10.60 227 281 7.7E-21 T 11-10-2018 AFK25_03175 c04051bf4f170241d4808bb569c6e619 282 Pfam PF12833 Helix-turn-helix domain 199 277 4.0E-22 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFK25_03175 c04051bf4f170241d4808bb569c6e619 282 Gene3D G3DSA:1.10.10.60 176 226 1.6E-11 T 11-10-2018 AFK25_03175 c04051bf4f170241d4808bb569c6e619 282 SUPERFAMILY SSF51215 5 124 4.32E-16 T 11-10-2018 IPR037923 Transcription regulator HTH-like AFK25_03175 c04051bf4f170241d4808bb569c6e619 282 Gene3D G3DSA:2.60.120.10 24 98 2.5E-6 T 11-10-2018 IPR014710 RmlC-like jelly roll fold AFK25_03175 c04051bf4f170241d4808bb569c6e619 282 Pfam PF02311 AraC-like ligand binding domain 30 95 1.6E-5 T 11-10-2018 IPR003313 AraC-type arabinose-binding/dimerisation domain GO:0006355 AFK25_03175 c04051bf4f170241d4808bb569c6e619 282 SUPERFAMILY SSF46689 180 227 1.93E-6 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_03175 c04051bf4f170241d4808bb569c6e619 282 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 260 276 9.1E-8 T 11-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFK25_03175 c04051bf4f170241d4808bb569c6e619 282 PRINTS PR00032 AraC bacterial regulatory protein HTH signature 245 260 9.1E-8 T 11-10-2018 IPR020449 Transcription regulator HTH, AraC- type GO:0003700|GO:0006355 AFK25_03175 c04051bf4f170241d4808bb569c6e619 282 SMART SM00342 193 276 5.0E-26 T 11-10-2018 IPR018060 DNA binding HTH domain, AraC-type GO:0003700|GO:0006355|GO:0043565 AFK25_05335 7a94082d46ff64cdd6fd0e427ab55e11 430 ProSitePatterns PS01116 Xanthine/uracil permeases family signature. 334 354 - T 11-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 AFK25_05335 7a94082d46ff64cdd6fd0e427ab55e11 430 TIGRFAM TIGR00801 ncs2: uracil-xanthine permease 13 411 7.2E-133 T 11-10-2018 IPR006042 Xanthine/uracil permease GO:0005215|GO:0016020|GO:0055085 Reactome: R-HSA-196836 AFK25_05335 7a94082d46ff64cdd6fd0e427ab55e11 430 Pfam PF00860 Permease family 15 387 1.3E-110 T 11-10-2018 IPR006043 Xanthine/uracil/vitamin C permease GO:0016020|GO:0022857|GO:0055085 AFK25_09365 2fefa34c41c954677fb9b853e5c1631b 437 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 17 429 41.654 T 11-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFK25_09365 2fefa34c41c954677fb9b853e5c1631b 437 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 61 79 - T 11-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site AFK25_09365 2fefa34c41c954677fb9b853e5c1631b 437 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 37 294 3.7E-73 T 11-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 AFK25_09365 2fefa34c41c954677fb9b853e5c1631b 437 Gene3D G3DSA:2.40.37.10 15 425 9.4E-160 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFK25_09365 2fefa34c41c954677fb9b853e5c1631b 437 PRINTS PR01181 Diaminopimelate decarboxylase signature 168 177 7.5E-32 T 11-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFK25_09365 2fefa34c41c954677fb9b853e5c1631b 437 PRINTS PR01181 Diaminopimelate decarboxylase signature 396 418 7.5E-32 T 11-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFK25_09365 2fefa34c41c954677fb9b853e5c1631b 437 PRINTS PR01181 Diaminopimelate decarboxylase signature 79 96 7.5E-32 T 11-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFK25_09365 2fefa34c41c954677fb9b853e5c1631b 437 PRINTS PR01181 Diaminopimelate decarboxylase signature 314 332 7.5E-32 T 11-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFK25_09365 2fefa34c41c954677fb9b853e5c1631b 437 Gene3D G3DSA:3.20.20.10 36 295 9.4E-160 T 11-10-2018 IPR029066 PLP-binding barrel AFK25_09365 2fefa34c41c954677fb9b853e5c1631b 437 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 31 386 3.3E-17 T 11-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 AFK25_09365 2fefa34c41c954677fb9b853e5c1631b 437 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 7 428 1.8E-160 T 11-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AFK25_09365 2fefa34c41c954677fb9b853e5c1631b 437 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 61 79 1.2E-19 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFK25_09365 2fefa34c41c954677fb9b853e5c1631b 437 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 386 399 1.2E-19 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFK25_09365 2fefa34c41c954677fb9b853e5c1631b 437 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 196 209 1.2E-19 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFK25_09365 2fefa34c41c954677fb9b853e5c1631b 437 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 81 93 1.2E-19 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFK25_09365 2fefa34c41c954677fb9b853e5c1631b 437 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 285 304 1.2E-19 T 11-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AFK25_09365 2fefa34c41c954677fb9b853e5c1631b 437 SUPERFAMILY SSF51419 28 297 7.41E-83 T 11-10-2018 IPR029066 PLP-binding barrel AFK25_09365 2fefa34c41c954677fb9b853e5c1631b 437 SUPERFAMILY SSF50621 275 429 3.77E-55 T 11-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AFK25_07055 592016780101886ee534b5a064bef0d7 224 Pfam PF08241 Methyltransferase domain 51 142 1.1E-21 T 11-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AFK25_07055 592016780101886ee534b5a064bef0d7 224 SUPERFAMILY SSF53335 6 200 2.43E-38 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_07055 592016780101886ee534b5a064bef0d7 224 Gene3D G3DSA:3.40.50.150 24 224 4.6E-54 T 11-10-2018 AFK25_12005 adea36fb4be028a87396fb45a533107f 383 SUPERFAMILY SSF103473 7 379 3.14E-54 T 11-10-2018 IPR036259 MFS transporter superfamily AFK25_12005 adea36fb4be028a87396fb45a533107f 383 Pfam PF12832 MFS_1 like family 6 348 8.6E-49 T 11-10-2018 IPR024989 Major facilitator superfamily associated domain AFK25_12005 adea36fb4be028a87396fb45a533107f 383 Gene3D G3DSA:1.20.1250.20 3 186 1.2E-32 T 11-10-2018 AFK25_12005 adea36fb4be028a87396fb45a533107f 383 Gene3D G3DSA:1.20.1250.20 187 380 7.1E-32 T 11-10-2018 AFK25_10445 4103a54c0b57dbe48713a4e292fe7656 155 TIGRFAM TIGR02571 ComEB: ComE operon protein 2 2 146 1.7E-88 T 11-10-2018 IPR013404 Competence operon E, ComEB AFK25_10445 4103a54c0b57dbe48713a4e292fe7656 155 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 70 106 - T 11-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 AFK25_10445 4103a54c0b57dbe48713a4e292fe7656 155 Gene3D G3DSA:3.40.140.10 2 146 4.2E-48 T 11-10-2018 AFK25_10445 4103a54c0b57dbe48713a4e292fe7656 155 SUPERFAMILY SSF53927 7 140 9.03E-42 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFK25_10445 4103a54c0b57dbe48713a4e292fe7656 155 PIRSF PIRSF006019 1 148 2.9E-60 T 11-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AFK25_10445 4103a54c0b57dbe48713a4e292fe7656 155 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 5 116 8.5E-30 T 11-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain AFK25_13610 9b4c61bebe084fc384437c63e6b0c521 285 PIRSF PIRSF012524 1 280 3.2E-102 T 11-10-2018 IPR014464 Conserved virulence factor B AFK25_13610 9b4c61bebe084fc384437c63e6b0c521 285 Gene3D G3DSA:2.40.50.140 150 217 2.7E-18 T 11-10-2018 AFK25_13610 9b4c61bebe084fc384437c63e6b0c521 285 Pfam PF13509 S1 domain 2 61 5.4E-19 T 11-10-2018 IPR039566 Conserved virulence factor B, S1 domain AFK25_13610 9b4c61bebe084fc384437c63e6b0c521 285 Gene3D G3DSA:2.40.50.140 70 147 3.0E-30 T 11-10-2018 AFK25_13610 9b4c61bebe084fc384437c63e6b0c521 285 Gene3D G3DSA:1.10.10.10 218 279 4.4E-24 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_06305 12f0845f11772c27303f496a9c74b8ff 561 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 112 535 1.5E-223 T 11-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFK25_06305 12f0845f11772c27303f496a9c74b8ff 561 Pfam PF01964 Radical SAM ThiC family 113 533 5.4E-206 T 11-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFK25_06305 12f0845f11772c27303f496a9c74b8ff 561 Pfam PF13667 ThiC-associated domain 10 86 6.3E-32 T 11-10-2018 IPR025747 ThiC-associated domain KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFK25_06305 12f0845f11772c27303f496a9c74b8ff 561 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 112 538 99.523 T 11-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFK25_06305 12f0845f11772c27303f496a9c74b8ff 561 Gene3D G3DSA:3.20.20.540 156 469 4.1E-156 T 11-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AFK25_04605 8169b91811911d44f255487b05c915e7 490 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 132 151 1.1E-15 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_04605 8169b91811911d44f255487b05c915e7 490 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 234 258 1.1E-15 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_04605 8169b91811911d44f255487b05c915e7 490 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 322 341 1.1E-15 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_04605 8169b91811911d44f255487b05c915e7 490 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 162 186 1.1E-15 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_04605 8169b91811911d44f255487b05c915e7 490 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 374 400 1.1E-15 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_04605 8169b91811911d44f255487b05c915e7 490 Pfam PF00361 Proton-conducting membrane transporter 127 416 9.1E-52 T 11-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_12145 158b690acbb7b60a845cfd5ee5c6b5ef 361 Pfam PF00487 Fatty acid desaturase 55 299 4.4E-30 T 11-10-2018 IPR005804 Fatty acid desaturase domain GO:0006629 AFK25_13205 8b42e2e8791732076325baf81897dc11 323 Pfam PF02719 Polysaccharide biosynthesis protein 9 279 2.7E-105 T 11-10-2018 IPR003869 Polysaccharide biosynthesis protein, CapD-like domain AFK25_13205 8b42e2e8791732076325baf81897dc11 323 SUPERFAMILY SSF51735 3 271 1.04E-54 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_13205 8b42e2e8791732076325baf81897dc11 323 Gene3D G3DSA:3.40.50.720 6 303 1.8E-135 T 11-10-2018 AFK25_13205 8b42e2e8791732076325baf81897dc11 323 Gene3D G3DSA:3.90.25.30 168 307 1.8E-135 T 11-10-2018 AFK25_13205 8b42e2e8791732076325baf81897dc11 323 TIGRFAM TIGR03589 PseB: UDP-N-acetylglucosamine 4,6-dehydratase (inverting) 3 319 6.7E-167 T 11-10-2018 IPR020025 UDP-N-acetylglucosamine 4,6-dehydratase (inverting) KEGG: 00520+4.2.1.115|MetaCyc: PWY-6143|MetaCyc: PWY-7330|MetaCyc: PWY-7331|MetaCyc: PWY-7332|MetaCyc: PWY-7719 AFK25_02385 37621f588741d51fe209b44bc0343908 506 TIGRFAM TIGR01539 portal_lambda: phage portal protein, lambda family 52 501 7.7E-85 T 11-10-2018 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 AFK25_02385 37621f588741d51fe209b44bc0343908 506 Pfam PF05136 Phage portal protein, lambda family 45 395 6.5E-122 T 11-10-2018 IPR006429 Phage portal protein, lambda family GO:0005198|GO:0019068 AFK25_09345 e97d874ee1cb1311c8ab0939cadaca17 212 Pfam PF00677 Lumazine binding domain 3 86 8.0E-25 T 11-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFK25_09345 e97d874ee1cb1311c8ab0939cadaca17 212 Pfam PF00677 Lumazine binding domain 99 183 1.3E-22 T 11-10-2018 IPR026017 Lumazine-binding domain KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFK25_09345 e97d874ee1cb1311c8ab0939cadaca17 212 Gene3D G3DSA:2.40.30.20 1 88 3.3E-32 T 11-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFK25_09345 e97d874ee1cb1311c8ab0939cadaca17 212 PIRSF PIRSF000498 1 208 4.3E-78 T 11-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFK25_09345 e97d874ee1cb1311c8ab0939cadaca17 212 SUPERFAMILY SSF63380 92 196 3.74E-33 T 11-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFK25_09345 e97d874ee1cb1311c8ab0939cadaca17 212 Gene3D G3DSA:2.40.30.20 101 203 4.3E-34 T 11-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AFK25_09345 e97d874ee1cb1311c8ab0939cadaca17 212 TIGRFAM TIGR00187 ribE: riboflavin synthase, alpha subunit 1 198 9.8E-80 T 11-10-2018 IPR001783 Lumazine-binding protein KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFK25_09345 e97d874ee1cb1311c8ab0939cadaca17 212 SUPERFAMILY SSF63380 1 89 3.32E-28 T 11-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AFK25_10010 c924b6440180a4266a05a1ce7f6e341f 144 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 6 26 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_10010 c924b6440180a4266a05a1ce7f6e341f 144 Pfam PF15980 Putative Competence protein ComGF 41 131 3.2E-20 T 11-10-2018 IPR016977 Competence operon G, ComGF AFK25_10010 c924b6440180a4266a05a1ce7f6e341f 144 Pfam PF07963 Prokaryotic N-terminal methylation motif 4 27 9.7E-6 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_10010 c924b6440180a4266a05a1ce7f6e341f 144 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 6 26 4.9E-4 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_14245 e3fc80dee03efdaf0889eed8c96add94 160 TIGRFAM TIGR00830 PTBA: PTS system, glucose subfamily, IIA component 12 132 6.8E-49 T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 AFK25_14245 e3fc80dee03efdaf0889eed8c96add94 160 ProSitePatterns PS00371 PTS EIIA domains phosphorylation site signature 1. 74 86 - T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 AFK25_14245 e3fc80dee03efdaf0889eed8c96add94 160 Pfam PF00358 phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 11 134 7.3E-54 T 11-10-2018 IPR001127 Phosphotransferase system, sugar-specific permease EIIA type 1 GO:0009401 AFK25_14245 e3fc80dee03efdaf0889eed8c96add94 160 Gene3D G3DSA:2.70.70.10 5 158 2.1E-60 T 11-10-2018 IPR011055 Duplicated hybrid motif AFK25_14245 e3fc80dee03efdaf0889eed8c96add94 160 SUPERFAMILY SSF51261 4 155 4.84E-57 T 11-10-2018 IPR011055 Duplicated hybrid motif AFK25_12880 6244d37b9bed0ca5cd2bcf76b64adbc0 40 Pfam PF00113 Enolase, C-terminal TIM barrel domain 5 36 4.5E-9 T 11-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AFK25_12880 6244d37b9bed0ca5cd2bcf76b64adbc0 40 SUPERFAMILY SSF51604 6 37 1.36E-8 T 11-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFK25_12880 6244d37b9bed0ca5cd2bcf76b64adbc0 40 Gene3D G3DSA:3.20.20.120 1 40 1.1E-7 T 11-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AFK25_06225 b95cd25bb6dec77a1ab590099f240573 259 Pfam PF13527 Acetyltransferase (GNAT) domain 130 250 4.0E-12 T 11-10-2018 AFK25_06225 b95cd25bb6dec77a1ab590099f240573 259 SUPERFAMILY SSF55729 2 258 1.89E-22 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFK25_06225 b95cd25bb6dec77a1ab590099f240573 259 Gene3D G3DSA:3.40.630.30 45 258 1.2E-20 T 11-10-2018 AFK25_02220 5511989245c3f55034314cce1685b05c 389 Pfam PF04285 Protein of unknown function (DUF444) 192 380 3.2E-69 T 11-10-2018 IPR006698 Uncharacterised protein family UPF0229 AFK25_02220 5511989245c3f55034314cce1685b05c 389 Pfam PF04285 Protein of unknown function (DUF444) 10 181 1.0E-35 T 11-10-2018 IPR006698 Uncharacterised protein family UPF0229 AFK25_02220 5511989245c3f55034314cce1685b05c 389 TIGRFAM TIGR02877 spore_yhbH: sporulation protein YhbH 5 378 1.3E-180 T 11-10-2018 IPR014230 Sporulation protein YhbH AFK25_05060 10a596b520bcaa39de1cd43ece915555 359 Pfam PF01594 AI-2E family transporter 20 350 6.8E-56 T 11-10-2018 IPR002549 Transmembrane protein TqsA-like AFK25_05060 10a596b520bcaa39de1cd43ece915555 359 TIGRFAM TIGR02872 spore_ytvI: sporulation integral membrane protein YtvI 15 353 9.3E-93 T 11-10-2018 IPR014227 Putative transport protein YtvI-like AFK25_09145 ec95ca0dc98851f7bf6bfe3cd77c7240 524 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 141 168 - T 11-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 AFK25_09145 ec95ca0dc98851f7bf6bfe3cd77c7240 524 Pfam PF01842 ACT domain 452 514 2.1E-11 T 11-10-2018 IPR002912 ACT domain AFK25_09145 ec95ca0dc98851f7bf6bfe3cd77c7240 524 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 104 278 1.0E-65 T 11-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AFK25_09145 ec95ca0dc98851f7bf6bfe3cd77c7240 524 Gene3D G3DSA:3.30.70.260 451 524 1.4E-22 T 11-10-2018 AFK25_09145 ec95ca0dc98851f7bf6bfe3cd77c7240 524 Gene3D G3DSA:3.30.1330.90 315 450 7.8E-34 T 11-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 AFK25_09145 ec95ca0dc98851f7bf6bfe3cd77c7240 524 SUPERFAMILY SSF55021 448 522 4.2E-20 T 11-10-2018 AFK25_09145 ec95ca0dc98851f7bf6bfe3cd77c7240 524 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 189 211 - T 11-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AFK25_09145 ec95ca0dc98851f7bf6bfe3cd77c7240 524 SUPERFAMILY SSF143548 316 446 4.18E-34 T 11-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 AFK25_09145 ec95ca0dc98851f7bf6bfe3cd77c7240 524 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 3 523 3.5E-214 T 11-10-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 AFK25_09145 ec95ca0dc98851f7bf6bfe3cd77c7240 524 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 4 310 2.6E-36 T 11-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 AFK25_09145 ec95ca0dc98851f7bf6bfe3cd77c7240 524 SUPERFAMILY SSF51735 95 279 5.99E-65 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_09145 ec95ca0dc98851f7bf6bfe3cd77c7240 524 SUPERFAMILY SSF52283 10 126 4.91E-34 T 11-10-2018 AFK25_09145 ec95ca0dc98851f7bf6bfe3cd77c7240 524 Gene3D G3DSA:3.40.50.720 95 276 2.3E-119 T 11-10-2018 AFK25_09145 ec95ca0dc98851f7bf6bfe3cd77c7240 524 Gene3D G3DSA:3.40.50.720 5 302 2.3E-119 T 11-10-2018 AFK25_09145 ec95ca0dc98851f7bf6bfe3cd77c7240 524 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 218 234 - T 11-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AFK25_01210 284cc22bbaaf623e1e05409d0b74e27a 140 Pfam PF00583 Acetyltransferase (GNAT) family 7 116 9.5E-23 T 11-10-2018 IPR000182 GNAT domain AFK25_01210 284cc22bbaaf623e1e05409d0b74e27a 140 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 5 136 1.4E-46 T 11-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 AFK25_01210 284cc22bbaaf623e1e05409d0b74e27a 140 SUPERFAMILY SSF55729 1 140 6.73E-37 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFK25_01210 284cc22bbaaf623e1e05409d0b74e27a 140 Gene3D G3DSA:3.40.630.30 1 140 1.7E-45 T 11-10-2018 AFK25_02850 a8b27876121f9920464d779f0beecd27 247 Gene3D G3DSA:3.40.50.300 1 245 6.0E-61 T 11-10-2018 AFK25_02850 a8b27876121f9920464d779f0beecd27 247 SMART SM00382 28 213 6.4E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_02850 a8b27876121f9920464d779f0beecd27 247 SUPERFAMILY SSF52540 3 225 1.42E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_02850 a8b27876121f9920464d779f0beecd27 247 Pfam PF00005 ABC transporter 19 162 3.5E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_00380 510469193c491f2fd4b1664d3b784c54 257 SUPERFAMILY SSF53067 1 122 3.89E-39 T 11-10-2018 AFK25_00380 510469193c491f2fd4b1664d3b784c54 257 Pfam PF03309 Type III pantothenate kinase 3 205 2.8E-73 T 11-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 AFK25_00380 510469193c491f2fd4b1664d3b784c54 257 Hamap MF_01274 Type III pantothenate kinase [coaX]. 1 254 37.809 T 11-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 AFK25_00380 510469193c491f2fd4b1664d3b784c54 257 Gene3D G3DSA:3.30.420.40 89 257 1.4E-62 T 11-10-2018 AFK25_00380 510469193c491f2fd4b1664d3b784c54 257 TIGRFAM TIGR00671 baf: pantothenate kinase, type III 4 249 5.9E-85 T 11-10-2018 IPR004619 Type III pantothenate kinase GO:0004594 KEGG: 00770+2.7.1.33|MetaCyc: PWY-3961 AFK25_00380 510469193c491f2fd4b1664d3b784c54 257 Gene3D G3DSA:3.30.420.40 1 88 2.1E-34 T 11-10-2018 AFK25_00380 510469193c491f2fd4b1664d3b784c54 257 SUPERFAMILY SSF53067 124 253 4.92E-40 T 11-10-2018 AFK25_12495 9402ae05a1cf078a2bb7d82b32339752 77 Pfam PF04070 Domain of unknown function (DUF378) 3 61 5.4E-27 T 11-10-2018 IPR007211 Protein of unknown function DUF378 AFK25_11255 9af0c32b532dab9c439dfa372c77b0aa 136 Gene3D G3DSA:3.30.1380.20 1 134 1.8E-52 T 11-10-2018 AFK25_11255 9af0c32b532dab9c439dfa372c77b0aa 136 Pfam PF10702 Protein of unknown function (DUF2507) 6 127 3.0E-48 T 11-10-2018 IPR019642 Protein of unknown function DUF2507 AFK25_11255 9af0c32b532dab9c439dfa372c77b0aa 136 SUPERFAMILY SSF111126 8 115 6.28E-24 T 11-10-2018 IPR024096 NO signalling/Golgi transport ligand-binding domain superfamily AFK25_07255 c92be275938b7662a25e507acbd5c3cb 274 Pfam PF01226 Formate/nitrite transporter 11 249 1.0E-69 T 11-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 AFK25_07255 c92be275938b7662a25e507acbd5c3cb 274 TIGRFAM TIGR00790 fnt: formate/nitrite transporter 19 250 1.2E-71 T 11-10-2018 IPR000292 Formate/nitrite transporter GO:0016020|GO:0022857|GO:0055085 AFK25_07255 c92be275938b7662a25e507acbd5c3cb 274 ProSitePatterns PS01005 Formate and nitrite transporters signature 1. 74 83 - T 11-10-2018 IPR024002 Formate/nitrite transporter, conserved site AFK25_07255 c92be275938b7662a25e507acbd5c3cb 274 Gene3D G3DSA:1.20.1080.10 1 261 3.4E-84 T 11-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 AFK25_07255 c92be275938b7662a25e507acbd5c3cb 274 ProSitePatterns PS01006 Formate and nitrite transporters signature 2. 158 168 - T 11-10-2018 IPR024002 Formate/nitrite transporter, conserved site AFK25_05125 8c1d22ebbac55456b5c129325543f0a4 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 50 74 1.2E-51 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFK25_05125 8c1d22ebbac55456b5c129325543f0a4 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 21 42 1.2E-51 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFK25_05125 8c1d22ebbac55456b5c129325543f0a4 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 3 21 1.2E-51 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFK25_05125 8c1d22ebbac55456b5c129325543f0a4 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 86 102 1.2E-51 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFK25_05125 8c1d22ebbac55456b5c129325543f0a4 165 PRINTS PR01020 Lipopolysaccharide core biosynthesis protein signature 113 135 1.2E-51 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFK25_05125 8c1d22ebbac55456b5c129325543f0a4 165 Pfam PF01467 Cytidylyltransferase-like 7 134 9.9E-20 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFK25_05125 8c1d22ebbac55456b5c129325543f0a4 165 ProDom PD016147 LIGASE LYASE CITRATE PRO-3S-LYASE SYNTHETASE TRANSFERASE CYTIDYLTRANSFERASE-RELATED:CITRATE ACETATE:SH-CITRATE CITC PLASMID 12 150 1.0E-5 T 11-10-2018 AFK25_05125 8c1d22ebbac55456b5c129325543f0a4 165 TIGRFAM TIGR01510 coaD_prev_kdtB: pantetheine-phosphate adenylyltransferase 4 158 1.6E-63 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFK25_05125 8c1d22ebbac55456b5c129325543f0a4 165 SUPERFAMILY SSF52374 4 157 1.47E-44 T 11-10-2018 AFK25_05125 8c1d22ebbac55456b5c129325543f0a4 165 Hamap MF_00151 Phosphopantetheine adenylyltransferase [coaD]. 3 159 36.535 T 11-10-2018 IPR001980 Phosphopantetheine adenylyltransferase GO:0004595|GO:0015937 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AFK25_05125 8c1d22ebbac55456b5c129325543f0a4 165 Gene3D G3DSA:3.40.50.620 1 165 8.4E-60 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_05125 8c1d22ebbac55456b5c129325543f0a4 165 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 4 62 5.8E-18 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFK25_04030 6c92ea0da526285b7821a217d4beadc4 576 ProSitePatterns PS00211 ABC transporters family signature. 471 485 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_04030 6c92ea0da526285b7821a217d4beadc4 576 Pfam PF00664 ABC transporter transmembrane region 21 283 5.1E-41 T 11-10-2018 IPR011527 ABC transporter type 1, transmembrane domain GO:0005524|GO:0016021|GO:0042626|GO:0055085 AFK25_04030 6c92ea0da526285b7821a217d4beadc4 576 Gene3D G3DSA:3.40.50.300 323 575 1.0E-85 T 11-10-2018 AFK25_04030 6c92ea0da526285b7821a217d4beadc4 576 SUPERFAMILY SSF52540 324 567 2.37E-84 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_04030 6c92ea0da526285b7821a217d4beadc4 576 SMART SM00382 359 549 1.7E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_04030 6c92ea0da526285b7821a217d4beadc4 576 Gene3D G3DSA:1.20.1560.10 2 312 1.4E-83 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFK25_04030 6c92ea0da526285b7821a217d4beadc4 576 SUPERFAMILY SSF90123 5 311 5.36E-69 T 11-10-2018 IPR036640 ABC transporter type 1, transmembrane domain superfamily GO:0005524|GO:0016021 AFK25_04030 6c92ea0da526285b7821a217d4beadc4 576 Pfam PF00005 ABC transporter 350 499 1.7E-35 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_00545 bb0cbf2ae8d92f15edb688e8e44716b0 233 Gene3D G3DSA:3.40.50.790 68 159 4.6E-87 T 11-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich AFK25_00545 bb0cbf2ae8d92f15edb688e8e44716b0 233 Gene3D G3DSA:3.30.190.20 21 225 4.6E-87 T 11-10-2018 AFK25_00545 bb0cbf2ae8d92f15edb688e8e44716b0 233 Hamap MF_01318_B 50S ribosomal protein L1 [rplA]. 2 229 45.488 T 11-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 AFK25_00545 bb0cbf2ae8d92f15edb688e8e44716b0 233 Pfam PF00687 Ribosomal protein L1p/L10e family 31 220 4.7E-57 T 11-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein AFK25_00545 bb0cbf2ae8d92f15edb688e8e44716b0 233 ProSitePatterns PS01199 Ribosomal protein L1 signature. 121 139 - T 11-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00545 bb0cbf2ae8d92f15edb688e8e44716b0 233 TIGRFAM TIGR01169 rplA_bact: ribosomal protein uL1 3 227 3.5E-109 T 11-10-2018 IPR005878 Ribosomal protein L1, bacterial-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 AFK25_00545 bb0cbf2ae8d92f15edb688e8e44716b0 233 PIRSF PIRSF002155 1 227 1.2E-82 T 11-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00545 bb0cbf2ae8d92f15edb688e8e44716b0 233 SUPERFAMILY SSF56808 6 226 3.79E-87 T 11-10-2018 IPR023674 Ribosomal protein L1-like AFK25_03195 abf4136e48ef11842ec838eab61fa898 280 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 105 273 1.0E-20 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_03195 abf4136e48ef11842ec838eab61fa898 280 Gene3D G3DSA:1.10.3720.10 1 267 1.3E-65 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_03195 abf4136e48ef11842ec838eab61fa898 280 SUPERFAMILY SSF161098 5 280 6.45E-71 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_14270 2f23a5ec48adc186010a7255b739aacf 266 SMART SM00062 34 256 1.6E-68 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFK25_14270 2f23a5ec48adc186010a7255b739aacf 266 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 35 254 3.0E-67 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFK25_14270 2f23a5ec48adc186010a7255b739aacf 266 Gene3D G3DSA:3.40.190.10 118 216 2.4E-82 T 11-10-2018 AFK25_14270 2f23a5ec48adc186010a7255b739aacf 266 SMART SM00079 34 255 9.1E-6 T 11-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 AFK25_14270 2f23a5ec48adc186010a7255b739aacf 266 Gene3D G3DSA:3.40.190.10 40 253 2.4E-82 T 11-10-2018 AFK25_14270 2f23a5ec48adc186010a7255b739aacf 266 SUPERFAMILY SSF53850 3 256 6.11E-74 T 11-10-2018 AFK25_14610 3ae6ecdebac328847c64ee3fbf0424dc 196 Pfam PF06866 Protein of unknown function (DUF1256) 6 167 7.3E-67 T 11-10-2018 IPR009665 Protein of unknown function DUF1256 AFK25_14610 3ae6ecdebac328847c64ee3fbf0424dc 196 TIGRFAM TIGR02841 spore_YyaC: putative sporulation protein YyaC 31 169 1.0E-68 T 11-10-2018 IPR009665 Protein of unknown function DUF1256 AFK25_14610 3ae6ecdebac328847c64ee3fbf0424dc 196 SUPERFAMILY SSF53163 4 191 1.44E-56 T 11-10-2018 IPR023430 Peptidase HybD-like domain superfamily AFK25_11160 2298c8d79c8c77a5936bf41c1dc414dc 194 Hamap MF_01031 3-isopropylmalate dehydratase small subunit [leuD]. 1 194 39.535 T 11-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 AFK25_11160 2298c8d79c8c77a5936bf41c1dc414dc 194 Pfam PF00694 Aconitase C-terminal domain 3 123 1.1E-34 T 11-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 AFK25_11160 2298c8d79c8c77a5936bf41c1dc414dc 194 Gene3D G3DSA:3.20.19.10 1 178 7.8E-72 T 11-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 AFK25_11160 2298c8d79c8c77a5936bf41c1dc414dc 194 SUPERFAMILY SSF52016 3 179 4.91E-57 T 11-10-2018 AFK25_11160 2298c8d79c8c77a5936bf41c1dc414dc 194 TIGRFAM TIGR00171 leuD: 3-isopropylmalate dehydratase, small subunit 2 186 1.1E-79 T 11-10-2018 IPR004431 3-isopropylmalate dehydratase, small subunit GO:0003861|GO:0009098|GO:0009316 KEGG: 00290+4.2.1.33 AFK25_04465 4be7eee3ff58d13aacd736870d177353 284 Gene3D G3DSA:3.30.450.20 7 99 1.1E-5 T 11-10-2018 AFK25_04465 4be7eee3ff58d13aacd736870d177353 284 SUPERFAMILY SSF58104 110 282 1.05E-45 T 11-10-2018 AFK25_04465 4be7eee3ff58d13aacd736870d177353 284 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 146 282 4.5E-33 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_04465 4be7eee3ff58d13aacd736870d177353 284 SMART SM00086 83 125 1.0E-4 T 11-10-2018 IPR001610 PAC motif AFK25_04465 4be7eee3ff58d13aacd736870d177353 284 Gene3D G3DSA:1.10.287.950 106 284 1.0E-42 T 11-10-2018 AFK25_04465 4be7eee3ff58d13aacd736870d177353 284 SMART SM00283 111 281 5.4E-5 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_04465 4be7eee3ff58d13aacd736870d177353 284 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 11 128 2.7E-16 T 11-10-2018 IPR000014 PAS domain AFK25_04465 4be7eee3ff58d13aacd736870d177353 284 Pfam PF08447 PAS fold 33 115 1.7E-14 T 11-10-2018 IPR013655 PAS fold-3 GO:0005515 AFK25_04465 4be7eee3ff58d13aacd736870d177353 284 SUPERFAMILY SSF55785 21 127 5.58E-24 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_04025 13d6ddbb418da9ce4263b56455dc91e6 176 Pfam PF13592 Winged helix-turn helix 115 169 7.8E-17 T 11-10-2018 IPR025959 Winged helix-turn helix domain AFK25_04025 13d6ddbb418da9ce4263b56455dc91e6 176 SUPERFAMILY SSF46689 25 143 7.7E-12 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_04025 13d6ddbb418da9ce4263b56455dc91e6 176 Pfam PF13551 Winged helix-turn helix 32 93 3.7E-10 T 11-10-2018 AFK25_07690 15c6b877108c1768c4d9af5190c5b69a 355 Pfam PF00195 Chalcone and stilbene synthases, N-terminal domain 63 202 2.7E-16 T 11-10-2018 IPR001099 Chalcone/stilbene synthase, N-terminal AFK25_07690 15c6b877108c1768c4d9af5190c5b69a 355 ProSitePatterns PS00441 Chalcone and stilbene synthases active site. 131 147 - T 11-10-2018 IPR018088 Chalcone/stilbene synthase, active site GO:0009058|GO:0016746 KEGG: 00941+2.3.1.74|MetaCyc: PWY-5135|MetaCyc: PWY-6316|MetaCyc: PWY-6515|MetaCyc: PWY-6787|MetaCyc: PWY-7397|MetaCyc: PWY-7897 AFK25_07690 15c6b877108c1768c4d9af5190c5b69a 355 SUPERFAMILY SSF53901 54 352 4.12E-46 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_07690 15c6b877108c1768c4d9af5190c5b69a 355 PIRSF PIRSF000451 1 354 2.7E-115 T 11-10-2018 IPR011141 Polyketide synthase, type III GO:0009058|GO:0016747 AFK25_07690 15c6b877108c1768c4d9af5190c5b69a 355 Gene3D G3DSA:3.40.47.10 210 350 3.8E-44 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_07690 15c6b877108c1768c4d9af5190c5b69a 355 Gene3D G3DSA:3.40.47.10 3 204 8.9E-61 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_07690 15c6b877108c1768c4d9af5190c5b69a 355 Pfam PF02797 Chalcone and stilbene synthases, C-terminal domain 218 350 1.4E-20 T 11-10-2018 IPR012328 Chalcone/stilbene synthase, C-terminal AFK25_08155 6a9a1c5fb3035bf66bf6a7890b74b50e 270 Gene3D G3DSA:3.40.50.300 1 248 6.4E-68 T 11-10-2018 AFK25_08155 6a9a1c5fb3035bf66bf6a7890b74b50e 270 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_08155 6a9a1c5fb3035bf66bf6a7890b74b50e 270 SUPERFAMILY SSF52540 3 230 7.03E-62 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_08155 6a9a1c5fb3035bf66bf6a7890b74b50e 270 SMART SM00382 28 225 2.8E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_08155 6a9a1c5fb3035bf66bf6a7890b74b50e 270 Pfam PF00005 ABC transporter 20 167 1.0E-33 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_06780 2145362d8e50d22bb17759ca89b2cdb7 178 Pfam PF10628 Outer spore coat protein E (CotE) 3 172 1.3E-69 T 11-10-2018 IPR018901 Spore coat protein CotE AFK25_02785 8044a26341d715fe68885c0c61f342da 287 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 238 1.5E-18 T 11-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 AFK25_02785 8044a26341d715fe68885c0c61f342da 287 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 6 265 1.2E-43 T 11-10-2018 IPR000150 Cof family GO:0016787 AFK25_02785 8044a26341d715fe68885c0c61f342da 287 Gene3D G3DSA:3.40.50.1000 5 262 5.4E-74 T 11-10-2018 IPR023214 HAD superfamily AFK25_02785 8044a26341d715fe68885c0c61f342da 287 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 265 2.0E-53 T 11-10-2018 AFK25_02785 8044a26341d715fe68885c0c61f342da 287 SUPERFAMILY SSF56784 2 270 1.22E-56 T 11-10-2018 IPR036412 HAD-like superfamily AFK25_02785 8044a26341d715fe68885c0c61f342da 287 Gene3D G3DSA:3.30.1240.10 83 193 5.4E-74 T 11-10-2018 AFK25_12560 ce5e8a541345e4d49d98bd799b8cbe76 408 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 8 328 3.2E-50 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFK25_12560 ce5e8a541345e4d49d98bd799b8cbe76 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 3.3E-5 T 11-10-2018 AFK25_12560 ce5e8a541345e4d49d98bd799b8cbe76 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 162 180 3.3E-5 T 11-10-2018 AFK25_12560 ce5e8a541345e4d49d98bd799b8cbe76 408 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 104 122 3.3E-5 T 11-10-2018 AFK25_12560 ce5e8a541345e4d49d98bd799b8cbe76 408 SUPERFAMILY SSF51905 6 213 5.06E-30 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_12560 ce5e8a541345e4d49d98bd799b8cbe76 408 SUPERFAMILY SSF51905 154 340 1.19E-23 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_12560 ce5e8a541345e4d49d98bd799b8cbe76 408 Gene3D G3DSA:3.50.50.100 4 408 9.2E-146 T 11-10-2018 AFK25_06385 8cc416640c1ba8615707741188da1872 305 PRINTS PR00069 Aldo-keto reductase signature 101 119 9.7E-6 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFK25_06385 8cc416640c1ba8615707741188da1872 305 PRINTS PR00069 Aldo-keto reductase signature 132 149 9.7E-6 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFK25_06385 8cc416640c1ba8615707741188da1872 305 Pfam PF00248 Aldo/keto reductase family 15 297 1.9E-63 T 11-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFK25_06385 8cc416640c1ba8615707741188da1872 305 Gene3D G3DSA:3.20.20.100 1 305 8.4E-98 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFK25_06385 8cc416640c1ba8615707741188da1872 305 SUPERFAMILY SSF51430 1 299 1.31E-79 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFK25_12155 e07a97918d6421af32b2b72d05af609b 326 Pfam PF13379 NMT1-like family 36 256 3.2E-23 T 11-10-2018 AFK25_12155 e07a97918d6421af32b2b72d05af609b 326 Gene3D G3DSA:3.40.190.10 108 211 7.8E-50 T 11-10-2018 AFK25_12155 e07a97918d6421af32b2b72d05af609b 326 Gene3D G3DSA:3.40.190.10 32 301 7.8E-50 T 11-10-2018 AFK25_12155 e07a97918d6421af32b2b72d05af609b 326 SUPERFAMILY SSF53850 24 248 1.57E-32 T 11-10-2018 AFK25_01600 05f1ae5bdbe3eeac34d029ead349bce2 106 Pfam PF03551 Transcriptional regulator PadR-like family 10 81 5.4E-20 T 11-10-2018 IPR005149 Transcription regulator PadR, N-terminal AFK25_01600 05f1ae5bdbe3eeac34d029ead349bce2 106 Gene3D G3DSA:1.10.10.10 1 105 6.3E-33 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_01600 05f1ae5bdbe3eeac34d029ead349bce2 106 SUPERFAMILY SSF46785 2 94 2.89E-21 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_03725 a4314c4497819c43f82aac8f65246e62 143 SUPERFAMILY SSF55729 3 141 7.04E-37 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFK25_03725 a4314c4497819c43f82aac8f65246e62 143 Pfam PF13673 Acetyltransferase (GNAT) domain 22 138 1.7E-25 T 11-10-2018 IPR000182 GNAT domain AFK25_03725 a4314c4497819c43f82aac8f65246e62 143 Gene3D G3DSA:3.40.630.30 2 141 9.3E-44 T 11-10-2018 AFK25_03710 e6180dfb0915af7a2b2e00a02aae4e0b 132 Pfam PF01797 Transposase IS200 like 11 129 1.2E-39 T 11-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 AFK25_03710 e6180dfb0915af7a2b2e00a02aae4e0b 132 SUPERFAMILY SSF143422 2 130 7.06E-45 T 11-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 AFK25_03710 e6180dfb0915af7a2b2e00a02aae4e0b 132 SMART SM01321 10 129 4.5E-40 T 11-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 AFK25_03710 e6180dfb0915af7a2b2e00a02aae4e0b 132 Gene3D G3DSA:3.30.70.1290 1 131 2.2E-39 T 11-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 AFK25_05535 3be8286b0376a6170ed22a4ff9030d78 332 Gene3D G3DSA:3.40.50.300 107 309 1.4E-118 T 11-10-2018 AFK25_05535 3be8286b0376a6170ed22a4ff9030d78 332 SUPERFAMILY SSF47364 18 96 9.81E-21 T 11-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 AFK25_05535 3be8286b0376a6170ed22a4ff9030d78 332 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 46 320 3.3E-120 T 11-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 AFK25_05535 3be8286b0376a6170ed22a4ff9030d78 332 SMART SM00962 120 321 2.5E-129 T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFK25_05535 3be8286b0376a6170ed22a4ff9030d78 332 SUPERFAMILY SSF52540 117 320 1.67E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_05535 3be8286b0376a6170ed22a4ff9030d78 332 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 46 321 66.345 T 11-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 AFK25_05535 3be8286b0376a6170ed22a4ff9030d78 332 SMART SM00382 119 297 4.2E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_05535 3be8286b0376a6170ed22a4ff9030d78 332 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 294 307 - T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFK25_05535 3be8286b0376a6170ed22a4ff9030d78 332 Gene3D G3DSA:1.20.120.140 20 318 1.4E-118 T 11-10-2018 AFK25_05535 3be8286b0376a6170ed22a4ff9030d78 332 SMART SM00963 22 103 3.6E-25 T 11-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFK25_05535 3be8286b0376a6170ed22a4ff9030d78 332 Pfam PF02881 SRP54-type protein, helical bundle domain 34 99 1.6E-14 T 11-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFK25_05535 3be8286b0376a6170ed22a4ff9030d78 332 Pfam PF00448 SRP54-type protein, GTPase domain 121 320 7.3E-85 T 11-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AFK25_12545 6162aa04215cc7403ec27ef947d438ab 194 PIRSF PIRSF016661 1 189 8.0E-52 T 11-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 AFK25_12545 6162aa04215cc7403ec27ef947d438ab 194 Gene3D G3DSA:1.10.1760.20 1 188 2.8E-49 T 11-10-2018 AFK25_12545 6162aa04215cc7403ec27ef947d438ab 194 Pfam PF02632 BioY family 32 179 7.9E-36 T 11-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 AFK25_07280 91b35a3fd6d9175f247635aee967dd00 634 SUPERFAMILY SSF53300 442 628 2.97E-16 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFK25_07280 91b35a3fd6d9175f247635aee967dd00 634 SMART SM00327 439 630 4.1E-14 T 11-10-2018 IPR002035 von Willebrand factor, type A AFK25_07280 91b35a3fd6d9175f247635aee967dd00 634 Pfam PF00092 von Willebrand factor type A domain 443 591 8.3E-7 T 11-10-2018 IPR002035 von Willebrand factor, type A AFK25_07280 91b35a3fd6d9175f247635aee967dd00 634 Gene3D G3DSA:3.40.50.410 439 628 3.0E-10 T 11-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AFK25_05175 c060b1cb2e07eeb1e617d6485546edd7 131 PIRSF PIRSF030092 1 129 8.6E-30 T 11-10-2018 IPR016945 Uncharacterised conserved protein UCP030092 AFK25_05175 c060b1cb2e07eeb1e617d6485546edd7 131 Pfam PF11877 Protein of unknown function (DUF3397) 9 121 4.9E-27 T 11-10-2018 IPR024515 Protein of unknown function DUF3397 AFK25_12535 79a20a215a1c22aa17a7467f3db0f17e 441 Pfam PF03600 Citrate transporter 25 383 5.5E-54 T 11-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 AFK25_12535 79a20a215a1c22aa17a7467f3db0f17e 441 PRINTS PR00758 Arsenical pump membrane protein signature 379 404 3.2E-11 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFK25_12535 79a20a215a1c22aa17a7467f3db0f17e 441 PRINTS PR00758 Arsenical pump membrane protein signature 228 253 3.2E-11 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFK25_12535 79a20a215a1c22aa17a7467f3db0f17e 441 PRINTS PR00758 Arsenical pump membrane protein signature 412 436 3.2E-11 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFK25_12535 79a20a215a1c22aa17a7467f3db0f17e 441 PRINTS PR00758 Arsenical pump membrane protein signature 111 135 3.2E-11 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFK25_12535 79a20a215a1c22aa17a7467f3db0f17e 441 PRINTS PR00758 Arsenical pump membrane protein signature 287 311 3.2E-11 T 11-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AFK25_11025 9e9c0ca991d7a58b07fa75456d533026 553 Gene3D G3DSA:3.30.450.90 143 278 8.3E-49 T 11-10-2018 AFK25_11025 9e9c0ca991d7a58b07fa75456d533026 553 Gene3D G3DSA:3.30.300.160 62 142 4.1E-17 T 11-10-2018 AFK25_11025 9e9c0ca991d7a58b07fa75456d533026 553 SUPERFAMILY SSF160246 5 143 9.42E-46 T 11-10-2018 IPR037257 General secretory system II, protein E, N-terminal superfamily AFK25_11025 9e9c0ca991d7a58b07fa75456d533026 553 Pfam PF05157 Type II secretion system (T2SS), protein E, N-terminal domain 41 145 5.3E-28 T 11-10-2018 IPR007831 General secretory system II, protein E, N-terminal AFK25_11025 9e9c0ca991d7a58b07fa75456d533026 553 SUPERFAMILY SSF52540 167 550 1.27E-97 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_11025 9e9c0ca991d7a58b07fa75456d533026 553 SMART SM00382 306 427 0.0013 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_11025 9e9c0ca991d7a58b07fa75456d533026 553 Gene3D G3DSA:3.40.50.300 281 552 1.7E-114 T 11-10-2018 AFK25_11025 9e9c0ca991d7a58b07fa75456d533026 553 Pfam PF00437 Type II/IV secretion system protein 180 445 1.7E-78 T 11-10-2018 IPR001482 Type II/IV secretion system protein AFK25_09045 afe64fed31f5400a6f7643be74d16def 448 TIGRFAM TIGR02889 spore_YpeB: germination protein YpeB 3 438 1.2E-146 T 11-10-2018 IPR014239 Spore germination YpeB GO:0009847 AFK25_09045 afe64fed31f5400a6f7643be74d16def 448 Pfam PF14620 YpeB sporulation 14 372 4.7E-138 T 11-10-2018 IPR014239 Spore germination YpeB GO:0009847 AFK25_12775 08b1e53e65c987ecdd3a3084fdb2b941 89 SUPERFAMILY SSF52833 4 87 3.64E-14 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_12775 08b1e53e65c987ecdd3a3084fdb2b941 89 Gene3D G3DSA:3.40.30.10 2 87 9.6E-13 T 11-10-2018 AFK25_12775 08b1e53e65c987ecdd3a3084fdb2b941 89 Pfam PF00085 Thioredoxin 6 72 1.3E-8 T 11-10-2018 IPR013766 Thioredoxin domain GO:0045454 AFK25_03835 467fcb2582cd08f7681849c20b7160bd 59 SUPERFAMILY SSF47413 12 55 2.25E-8 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFK25_03835 467fcb2582cd08f7681849c20b7160bd 59 Pfam PF01381 Helix-turn-helix 12 41 5.1E-8 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFK25_03835 467fcb2582cd08f7681849c20b7160bd 59 Gene3D G3DSA:1.10.260.40 5 58 1.4E-8 T 11-10-2018 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 4 473 8.2E-180 T 11-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 Gene3D G3DSA:3.50.50.60 5 338 2.2E-113 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 Gene3D G3DSA:3.50.50.60 163 285 2.2E-113 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 354 462 7.8E-40 T 11-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 SUPERFAMILY SSF51905 2 343 1.55E-58 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 334 2.4E-63 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 39 49 - T 11-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 7 26 1.3E-36 T 11-10-2018 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 144 162 1.3E-36 T 11-10-2018 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 287 1.3E-36 T 11-10-2018 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 183 201 1.3E-36 T 11-10-2018 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 299 321 1.3E-36 T 11-10-2018 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 SUPERFAMILY SSF55424 350 472 2.06E-43 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 183 208 7.0E-71 T 11-10-2018 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 350 371 7.0E-71 T 11-10-2018 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 38 53 7.0E-71 T 11-10-2018 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 314 321 7.0E-71 T 11-10-2018 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 437 457 7.0E-71 T 11-10-2018 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 147 156 7.0E-71 T 11-10-2018 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 6 28 7.0E-71 T 11-10-2018 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 272 286 7.0E-71 T 11-10-2018 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 415 430 7.0E-71 T 11-10-2018 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 Gene3D G3DSA:3.30.390.30 353 473 9.5E-48 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFK25_09760 f99c0043b96503b5bb6f508a90acac74 473 PIRSF PIRSF000350 1 471 6.4E-88 T 11-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 AFK25_04500 d705c922d64eebc4622a8748d1308d3e 537 Gene3D G3DSA:1.10.287.950 225 535 1.6E-52 T 11-10-2018 AFK25_04500 d705c922d64eebc4622a8748d1308d3e 537 SMART SM00283 260 528 5.3E-34 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_04500 d705c922d64eebc4622a8748d1308d3e 537 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 326 461 2.6E-29 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_04500 d705c922d64eebc4622a8748d1308d3e 537 SUPERFAMILY SSF58104 207 534 2.7E-48 T 11-10-2018 AFK25_01520 12244ee5a5bae076eb00f692f775a2a0 373 SMART SM00857 9 160 3.5E-11 T 11-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFK25_01520 12244ee5a5bae076eb00f692f775a2a0 373 SUPERFAMILY SSF53041 10 151 2.62E-12 T 11-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 AFK25_01520 12244ee5a5bae076eb00f692f775a2a0 373 Gene3D G3DSA:1.10.10.2600 144 289 2.8E-10 T 11-10-2018 IPR038109 DNA-binding recombinase domain superfamily AFK25_01520 12244ee5a5bae076eb00f692f775a2a0 373 Pfam PF00239 Resolvase, N terminal domain 10 150 1.7E-13 T 11-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFK25_01520 12244ee5a5bae076eb00f692f775a2a0 373 Pfam PF07508 Recombinase 187 286 2.0E-18 T 11-10-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 AFK25_01520 12244ee5a5bae076eb00f692f775a2a0 373 Gene3D G3DSA:3.40.50.1390 4 118 2.0E-15 T 11-10-2018 AFK25_11805 ed385e24441ce38fa07d3cdab0813906 397 Gene3D G3DSA:3.30.2130.30 1 174 3.6E-59 T 11-10-2018 AFK25_11805 ed385e24441ce38fa07d3cdab0813906 397 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 175 369 1.7E-68 T 11-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 AFK25_11805 ed385e24441ce38fa07d3cdab0813906 397 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 6 377 2.2E-128 T 11-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 AFK25_11805 ed385e24441ce38fa07d3cdab0813906 397 SMART SM00981 74 165 1.5E-21 T 11-10-2018 IPR004114 THUMP domain GO:0003723 AFK25_11805 ed385e24441ce38fa07d3cdab0813906 397 SUPERFAMILY SSF52402 174 387 1.55E-52 T 11-10-2018 AFK25_11805 ed385e24441ce38fa07d3cdab0813906 397 SUPERFAMILY SSF143437 3 173 9.24E-53 T 11-10-2018 AFK25_11805 ed385e24441ce38fa07d3cdab0813906 397 Gene3D G3DSA:3.40.50.620 175 395 5.4E-73 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_11805 ed385e24441ce38fa07d3cdab0813906 397 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 397 160.302 T 11-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 AFK25_11805 ed385e24441ce38fa07d3cdab0813906 397 Pfam PF02926 THUMP domain 37 162 6.1E-21 T 11-10-2018 IPR004114 THUMP domain GO:0003723 AFK25_03600 fffc748daf9ee5096fb6513b429a21c5 313 Gene3D G3DSA:3.40.50.720 4 294 1.1E-97 T 11-10-2018 AFK25_03600 fffc748daf9ee5096fb6513b429a21c5 313 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 240 6.6E-59 T 11-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFK25_03600 fffc748daf9ee5096fb6513b429a21c5 313 SUPERFAMILY SSF51735 1 311 4.35E-91 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_03600 fffc748daf9ee5096fb6513b429a21c5 313 Gene3D G3DSA:3.90.25.10 175 306 1.1E-97 T 11-10-2018 AFK25_03600 fffc748daf9ee5096fb6513b429a21c5 313 PRINTS PR01713 Nucleotide sugar epimerase signature 273 290 2.8E-7 T 11-10-2018 AFK25_03600 fffc748daf9ee5096fb6513b429a21c5 313 PRINTS PR01713 Nucleotide sugar epimerase signature 211 226 2.8E-7 T 11-10-2018 AFK25_03600 fffc748daf9ee5096fb6513b429a21c5 313 PRINTS PR01713 Nucleotide sugar epimerase signature 234 249 2.8E-7 T 11-10-2018 AFK25_00750 9719a1e0b1ad3e434b61fd73a73568b2 284 SUPERFAMILY SSF52540 5 228 2.17E-69 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_00750 9719a1e0b1ad3e434b61fd73a73568b2 284 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_00750 9719a1e0b1ad3e434b61fd73a73568b2 284 Pfam PF00005 ABC transporter 22 168 9.3E-38 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_00750 9719a1e0b1ad3e434b61fd73a73568b2 284 TIGRFAM TIGR04520 ECF_ATPase_1: energy-coupling factor transporter ATPase 5 272 9.9E-123 T 11-10-2018 IPR030947 Energy-coupling factor transporter ATP-binding protein EcfA1 AFK25_00750 9719a1e0b1ad3e434b61fd73a73568b2 284 Gene3D G3DSA:3.40.50.300 2 277 2.5E-86 T 11-10-2018 AFK25_00750 9719a1e0b1ad3e434b61fd73a73568b2 284 SMART SM00382 31 216 2.0E-17 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_01690 9006c3c5e7d4bb186fc44e6048d65951 76 SUPERFAMILY SSF50037 6 75 2.29E-16 T 11-10-2018 IPR008988 Transcriptional repressor, C-terminal AFK25_01690 9006c3c5e7d4bb186fc44e6048d65951 76 SMART SM00899 2 75 1.7E-14 T 11-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 AFK25_01690 9006c3c5e7d4bb186fc44e6048d65951 76 Pfam PF04023 FeoA domain 3 75 9.4E-14 T 11-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 AFK25_01690 9006c3c5e7d4bb186fc44e6048d65951 76 Gene3D G3DSA:2.30.30.90 1 75 1.0E-17 T 11-10-2018 IPR038157 Ferrous iron transporter, core domain AFK25_01615 b523b2081153fcf1b314e7ee4d581914 323 Pfam PF00005 ABC transporter 27 169 3.7E-28 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_01615 b523b2081153fcf1b314e7ee4d581914 323 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_01615 b523b2081153fcf1b314e7ee4d581914 323 Pfam PF13732 Domain of unknown function (DUF4162) 223 312 3.7E-6 T 11-10-2018 IPR025302 Domain of unknown function DUF4162 AFK25_01615 b523b2081153fcf1b314e7ee4d581914 323 SUPERFAMILY SSF52540 5 243 1.2E-62 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_01615 b523b2081153fcf1b314e7ee4d581914 323 SMART SM00382 35 218 9.6E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_01615 b523b2081153fcf1b314e7ee4d581914 323 Gene3D G3DSA:3.40.50.300 2 243 2.1E-67 T 11-10-2018 AFK25_01615 b523b2081153fcf1b314e7ee4d581914 323 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 18 314 1.0E-113 T 11-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 AFK25_08580 52d70a923c6fea1c1f7cbfc89694e6c1 609 SUPERFAMILY SSF51735 400 533 1.62E-12 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_08580 52d70a923c6fea1c1f7cbfc89694e6c1 609 Gene3D G3DSA:3.40.50.720 397 526 3.7E-13 T 11-10-2018 AFK25_08580 52d70a923c6fea1c1f7cbfc89694e6c1 609 Gene3D G3DSA:3.30.70.1450 527 608 1.2E-19 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFK25_08580 52d70a923c6fea1c1f7cbfc89694e6c1 609 SUPERFAMILY SSF116726 533 604 9.02E-11 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFK25_08580 52d70a923c6fea1c1f7cbfc89694e6c1 609 Gene3D G3DSA:1.20.1530.20 2 396 9.2E-75 T 11-10-2018 IPR038770 Sodium/solute symporter superfamily AFK25_08580 52d70a923c6fea1c1f7cbfc89694e6c1 609 Pfam PF02080 TrkA-C domain 549 604 1.8E-8 T 11-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFK25_08580 52d70a923c6fea1c1f7cbfc89694e6c1 609 Pfam PF00999 Sodium/hydrogen exchanger family 9 384 6.7E-75 T 11-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AFK25_08580 52d70a923c6fea1c1f7cbfc89694e6c1 609 Pfam PF02254 TrkA-N domain 400 508 2.6E-9 T 11-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AFK25_05615 4be289a916aa4c56d6701920cfe6ba7a 295 Gene3D G3DSA:3.40.50.450 6 294 3.3E-96 T 11-10-2018 AFK25_05615 4be289a916aa4c56d6701920cfe6ba7a 295 TIGRFAM TIGR00732 dprA: DNA protecting protein DprA 72 289 1.2E-79 T 11-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 AFK25_05615 4be289a916aa4c56d6701920cfe6ba7a 295 SUPERFAMILY SSF102405 83 290 1.42E-36 T 11-10-2018 AFK25_05615 4be289a916aa4c56d6701920cfe6ba7a 295 Pfam PF02481 DNA recombination-mediator protein A 74 281 6.1E-80 T 11-10-2018 IPR003488 DNA recombination-mediator protein A GO:0009294 AFK25_08760 477495a8a6d0089e390f0433e5ee340d 246 SUPERFAMILY SSF56281 32 243 8.98E-9 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_08760 477495a8a6d0089e390f0433e5ee340d 246 Gene3D G3DSA:3.60.15.10 133 245 2.2E-9 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_08930 531bf3e6ef90b83006f998257bf51fd6 148 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 38.532 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFK25_08930 531bf3e6ef90b83006f998257bf51fd6 148 Gene3D G3DSA:3.30.70.141 1 148 8.7E-67 T 11-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFK25_08930 531bf3e6ef90b83006f998257bf51fd6 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 1.1E-52 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFK25_08930 531bf3e6ef90b83006f998257bf51fd6 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 1.1E-52 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFK25_08930 531bf3e6ef90b83006f998257bf51fd6 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 1.1E-52 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFK25_08930 531bf3e6ef90b83006f998257bf51fd6 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 1.1E-52 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFK25_08930 531bf3e6ef90b83006f998257bf51fd6 148 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 1.1E-52 T 11-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFK25_08930 531bf3e6ef90b83006f998257bf51fd6 148 Pfam PF00334 Nucleoside diphosphate kinase 2 135 5.3E-61 T 11-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFK25_08930 531bf3e6ef90b83006f998257bf51fd6 148 SUPERFAMILY SSF54919 1 148 8.12E-64 T 11-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFK25_08930 531bf3e6ef90b83006f998257bf51fd6 148 SMART SM00562 1 138 3.1E-97 T 11-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AFK25_08930 531bf3e6ef90b83006f998257bf51fd6 148 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 11-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_03885 26bde0f223622fc5d5e60d9cd299d3c3 286 Pfam PF14281 PD-(D/E)XK nuclease superfamily 13 159 7.0E-9 T 11-10-2018 IPR029470 PD-(D/E)XK nuclease superfamily 4 AFK25_05820 ee2cc403732ddc35c8c217d75a95e3d5 235 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 2 228 44.833 T 11-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_05820 ee2cc403732ddc35c8c217d75a95e3d5 235 Gene3D G3DSA:3.40.50.10490 10 214 1.1E-99 T 11-10-2018 AFK25_05820 ee2cc403732ddc35c8c217d75a95e3d5 235 TIGRFAM TIGR01011 rpsB_bact: ribosomal protein uS2 3 226 1.9E-115 T 11-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_05820 ee2cc403732ddc35c8c217d75a95e3d5 235 ProSitePatterns PS00962 Ribosomal protein S2 signature 1. 6 17 - T 11-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 AFK25_05820 ee2cc403732ddc35c8c217d75a95e3d5 235 Gene3D G3DSA:1.10.287.610 97 152 1.1E-99 T 11-10-2018 AFK25_05820 ee2cc403732ddc35c8c217d75a95e3d5 235 PRINTS PR00395 Ribosomal protein S2 signature 196 210 3.0E-42 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_05820 ee2cc403732ddc35c8c217d75a95e3d5 235 PRINTS PR00395 Ribosomal protein S2 signature 87 104 3.0E-42 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_05820 ee2cc403732ddc35c8c217d75a95e3d5 235 PRINTS PR00395 Ribosomal protein S2 signature 6 24 3.0E-42 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_05820 ee2cc403732ddc35c8c217d75a95e3d5 235 PRINTS PR00395 Ribosomal protein S2 signature 158 175 3.0E-42 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_05820 ee2cc403732ddc35c8c217d75a95e3d5 235 PRINTS PR00395 Ribosomal protein S2 signature 37 46 3.0E-42 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_05820 ee2cc403732ddc35c8c217d75a95e3d5 235 PRINTS PR00395 Ribosomal protein S2 signature 175 186 3.0E-42 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_05820 ee2cc403732ddc35c8c217d75a95e3d5 235 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 158 182 - T 11-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 AFK25_05820 ee2cc403732ddc35c8c217d75a95e3d5 235 Pfam PF00318 Ribosomal protein S2 9 224 2.7E-105 T 11-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_05820 ee2cc403732ddc35c8c217d75a95e3d5 235 SUPERFAMILY SSF52313 6 229 8.5E-103 T 11-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily AFK25_11870 bd2f1dbeb539c93c5392a077a218d65f 390 Pfam PF00850 Histone deacetylase domain 22 316 5.7E-77 T 11-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFK25_11870 bd2f1dbeb539c93c5392a077a218d65f 390 SUPERFAMILY SSF52768 6 376 3.12E-107 T 11-10-2018 IPR023696 Ureohydrolase domain superfamily AFK25_11870 bd2f1dbeb539c93c5392a077a218d65f 390 Gene3D G3DSA:3.40.800.20 2 347 1.1E-102 T 11-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFK25_11870 bd2f1dbeb539c93c5392a077a218d65f 390 PRINTS PR01270 Histone deacetylase superfamily signature 130 153 6.5E-17 T 11-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFK25_11870 bd2f1dbeb539c93c5392a077a218d65f 390 PRINTS PR01270 Histone deacetylase superfamily signature 249 259 6.5E-17 T 11-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFK25_11870 bd2f1dbeb539c93c5392a077a218d65f 390 PRINTS PR01270 Histone deacetylase superfamily signature 163 178 6.5E-17 T 11-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AFK25_11870 bd2f1dbeb539c93c5392a077a218d65f 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 86 100 6.6E-47 T 11-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 AFK25_11870 bd2f1dbeb539c93c5392a077a218d65f 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 313 332 6.6E-47 T 11-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 AFK25_11870 bd2f1dbeb539c93c5392a077a218d65f 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 274 290 6.6E-47 T 11-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 AFK25_11870 bd2f1dbeb539c93c5392a077a218d65f 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 351 370 6.6E-47 T 11-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 AFK25_11870 bd2f1dbeb539c93c5392a077a218d65f 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 16 36 6.6E-47 T 11-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 AFK25_11870 bd2f1dbeb539c93c5392a077a218d65f 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 107 120 6.6E-47 T 11-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 AFK25_11870 bd2f1dbeb539c93c5392a077a218d65f 390 PRINTS PR01272 Acetoin utilisation ACUC protein signature 334 350 6.6E-47 T 11-10-2018 IPR003085 Acetoin utilization protein AcuC GO:0045149 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 Gene3D G3DSA:3.30.390.30 347 467 5.8E-45 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 SUPERFAMILY SSF55424 345 467 4.64E-42 T 11-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 12 31 1.4E-42 T 11-10-2018 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 178 196 1.4E-42 T 11-10-2018 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 140 158 1.4E-42 T 11-10-2018 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 265 281 1.4E-42 T 11-10-2018 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 294 316 1.4E-42 T 11-10-2018 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 178 203 1.4E-75 T 11-10-2018 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 409 424 1.4E-75 T 11-10-2018 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 431 451 1.4E-75 T 11-10-2018 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 11 33 1.4E-75 T 11-10-2018 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 266 280 1.4E-75 T 11-10-2018 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 309 316 1.4E-75 T 11-10-2018 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 344 365 1.4E-75 T 11-10-2018 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 143 152 1.4E-75 T 11-10-2018 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 43 58 1.4E-75 T 11-10-2018 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 348 456 7.0E-37 T 11-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 PIRSF PIRSF000350 3 458 9.2E-102 T 11-10-2018 IPR001100 Pyridine nucleotide-disulphide oxidoreductase, class I GO:0009055|GO:0016491 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 ProSitePatterns PS00076 Pyridine nucleotide-disulphide oxidoreductases class-I active site. 44 54 - T 11-10-2018 IPR012999 Pyridine nucleotide-disulphide oxidoreductase, class I, active site GO:0016668|GO:0055114 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 SUPERFAMILY SSF51905 9 339 1.86E-68 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 TIGRFAM TIGR01350 lipoamide_DH: dihydrolipoyl dehydrogenase 10 467 7.8E-180 T 11-10-2018 IPR006258 Dihydrolipoamide dehydrogenase GO:0004148|GO:0050660|GO:0055114 KEGG: 00010+1.8.1.4|KEGG: 00020+1.8.1.4|KEGG: 00260+1.8.1.4|KEGG: 00280+1.8.1.4|KEGG: 00620+1.8.1.4|KEGG: 00640+1.8.1.4|MetaCyc: PWY-5046|MetaCyc: PWY-5084|Reactome: R-HSA-204174|Reactome: R-HSA-389661|Reactome: R-HSA-5362517|Reactome: R-HSA-6783984|Reactome: R-HSA-70268|Reactome: R-HSA-70895|Reactome: R-HSA-71064|Reactome: R-HSA-71403 AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 Gene3D G3DSA:3.50.50.60 13 334 1.4E-129 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 Gene3D G3DSA:3.50.50.60 152 272 1.4E-129 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_04875 98f6a2f28255091cae369e5312c3782d 470 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 12 329 9.4E-76 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFK25_11780 a067af9a437fa0f0bc3aa3bfeeea2a42 294 Pfam PF02653 Branched-chain amino acid transport system / permease component 8 278 3.8E-35 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFK25_10855 91ee1ae89f4294092440af8d305c8f27 231 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 14 220 1.2E-35 T 11-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like AFK25_01310 6c012f24f23dc70554d7a118344a2f56 228 SMART SM01211 1 220 3.4E-139 T 11-10-2018 AFK25_01310 6c012f24f23dc70554d7a118344a2f56 228 Gene3D G3DSA:3.40.50.880 1 222 1.6E-75 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_01310 6c012f24f23dc70554d7a118344a2f56 228 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 2 204 1.2E-45 T 11-10-2018 AFK25_01310 6c012f24f23dc70554d7a118344a2f56 228 SUPERFAMILY SSF52317 2 220 9.73E-79 T 11-10-2018 IPR029062 Class I glutamine amidotransferase-like AFK25_01310 6c012f24f23dc70554d7a118344a2f56 228 PIRSF PIRSF001586 1 223 2.4E-91 T 11-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFK25_01310 6c012f24f23dc70554d7a118344a2f56 228 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 1 219 1.0E-98 T 11-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFK25_01310 6c012f24f23dc70554d7a118344a2f56 228 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 1 218 45.973 T 11-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AFK25_09000 146a1fb59fe4b712f0a95ef018004ca4 199 PIRSF PIRSF036710 1 199 3.6E-46 T 11-10-2018 IPR014617 Predicted membrane protein, Bacillus YphA type AFK25_09700 bd1462ac09ad59ca51130df84efb6c33 155 Gene3D G3DSA:2.40.50.180 22 130 4.8E-30 T 11-10-2018 AFK25_09700 bd1462ac09ad59ca51130df84efb6c33 155 SMART SM00260 1 135 1.3E-24 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFK25_09700 bd1462ac09ad59ca51130df84efb6c33 155 Pfam PF01584 CheW-like domain 4 138 3.5E-31 T 11-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AFK25_09700 bd1462ac09ad59ca51130df84efb6c33 155 Gene3D G3DSA:2.30.30.40 5 129 4.8E-30 T 11-10-2018 AFK25_09700 bd1462ac09ad59ca51130df84efb6c33 155 SUPERFAMILY SSF50341 3 138 1.96E-32 T 11-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 AFK25_12520 88b32f216462a491bedd11bd66b709c8 167 ProSitePatterns PS00332 Copper/Zinc superoxide dismutase signature 2. 153 164 - T 11-10-2018 IPR018152 Superoxide dismutase, copper/zinc, binding site GO:0004784|GO:0055114 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AFK25_12520 88b32f216462a491bedd11bd66b709c8 167 Gene3D G3DSA:2.60.40.200 19 167 2.1E-54 T 11-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AFK25_12520 88b32f216462a491bedd11bd66b709c8 167 SUPERFAMILY SSF49329 24 165 1.3E-45 T 11-10-2018 IPR036423 Superoxide dismutase-like, copper/zinc binding domain superfamily GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AFK25_12520 88b32f216462a491bedd11bd66b709c8 167 Pfam PF00080 Copper/zinc superoxide dismutase (SODC) 30 164 8.0E-44 T 11-10-2018 IPR001424 Superoxide dismutase, copper/zinc binding domain GO:0006801|GO:0046872 MetaCyc: PWY-6854|Reactome: R-HSA-3299685 AFK25_02685 dc818655caa65d66b07c678c84e47791 196 PIRSF PIRSF037394 1 194 7.6E-62 T 11-10-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted AFK25_02685 dc818655caa65d66b07c678c84e47791 196 Pfam PF09819 ABC-type cobalt transport system, permease component 12 128 4.7E-37 T 11-10-2018 IPR017195 ABC-type thiamin-related transport system, permease component 1, predicted AFK25_10420 81ef2e33781a96d582db7fb53cb9afe8 88 TIGRFAM TIGR00029 S20: ribosomal protein bS20 1 86 2.6E-32 T 11-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_10420 81ef2e33781a96d582db7fb53cb9afe8 88 Pfam PF01649 Ribosomal protein S20 2 84 1.5E-29 T 11-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_10420 81ef2e33781a96d582db7fb53cb9afe8 88 Gene3D G3DSA:1.20.58.110 1 87 8.4E-32 T 11-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_10420 81ef2e33781a96d582db7fb53cb9afe8 88 SUPERFAMILY SSF46992 3 86 2.35E-31 T 11-10-2018 IPR036510 Ribosomal protein S20 superfamily GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_10420 81ef2e33781a96d582db7fb53cb9afe8 88 Hamap MF_00500 30S ribosomal protein S20 [rpsT]. 1 85 18.576 T 11-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_10420 81ef2e33781a96d582db7fb53cb9afe8 88 ProDom PD004231 RIBOSOMAL S20 30S RRNA-BINDING RNA-BINDING RIBONUCLEOPROTEIN S20P SUBUNIT CHLOROPLAST DIRECT 14 88 1.0E-23 T 11-10-2018 IPR002583 Ribosomal protein S20 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_09865 c48ab3b30d7c62bdfda2e5bf919680dc 187 Pfam PF12685 SpoIIIAH-like protein 5 177 1.7E-36 T 11-10-2018 IPR024232 Stage III sporulation protein AH-like AFK25_09865 c48ab3b30d7c62bdfda2e5bf919680dc 187 Gene3D G3DSA:3.30.300.270 74 187 6.7E-39 T 11-10-2018 IPR038503 Stage III sporulation protein AH-like superfamily AFK25_10920 448587ce12a8e146dd64b96f4e82dbb9 96 SUPERFAMILY SSF110324 10 91 1.33E-31 T 11-10-2018 AFK25_10920 448587ce12a8e146dd64b96f4e82dbb9 96 ProSitePatterns PS00831 Ribosomal protein L27 signature. 42 56 - T 11-10-2018 IPR018261 Ribosomal protein L27, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_10920 448587ce12a8e146dd64b96f4e82dbb9 96 Pfam PF01016 Ribosomal L27 protein 10 89 7.5E-34 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10920 448587ce12a8e146dd64b96f4e82dbb9 96 PRINTS PR00063 Ribosomal protein L27 signature 62 86 2.9E-38 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10920 448587ce12a8e146dd64b96f4e82dbb9 96 PRINTS PR00063 Ribosomal protein L27 signature 12 36 2.9E-38 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10920 448587ce12a8e146dd64b96f4e82dbb9 96 PRINTS PR00063 Ribosomal protein L27 signature 37 61 2.9E-38 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10920 448587ce12a8e146dd64b96f4e82dbb9 96 Gene3D G3DSA:2.40.50.100 28 93 4.2E-26 T 11-10-2018 AFK25_10920 448587ce12a8e146dd64b96f4e82dbb9 96 Hamap MF_00539 50S ribosomal protein L27 [rpmA]. 9 92 26.712 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10920 448587ce12a8e146dd64b96f4e82dbb9 96 ProDom PD003114 RIBOSOMAL L27 50S RIBONUCLEOPROTEIN CHLOROPLAST MITOCHONDRIAL PEPTIDE 60S TRANSIT PRECURSOR 36 77 1.0E-16 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10920 448587ce12a8e146dd64b96f4e82dbb9 96 TIGRFAM TIGR00062 L27: ribosomal protein bL27 9 89 1.9E-39 T 11-10-2018 IPR001684 Ribosomal protein L27 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_03315 d3295ccce2e33016c4bb71e8fc0f71b4 615 Gene3D G3DSA:3.20.20.330 3 294 4.2E-89 T 11-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 AFK25_03315 d3295ccce2e33016c4bb71e8fc0f71b4 615 Pfam PF02574 Homocysteine S-methyltransferase 12 280 3.3E-57 T 11-10-2018 IPR003726 Homocysteine-binding domain Reactome: R-HSA-1614635 AFK25_03315 d3295ccce2e33016c4bb71e8fc0f71b4 615 Gene3D G3DSA:3.20.20.220 311 603 8.1E-50 T 11-10-2018 AFK25_03315 d3295ccce2e33016c4bb71e8fc0f71b4 615 Pfam PF02219 Methylenetetrahydrofolate reductase 318 571 1.3E-23 T 11-10-2018 IPR003171 Methylenetetrahydrofolate reductase GO:0004489|GO:0006555|GO:0055114 KEGG: 00670+1.5.1.20|KEGG: 00720+1.5.1.20|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 AFK25_03315 d3295ccce2e33016c4bb71e8fc0f71b4 615 SUPERFAMILY SSF51730 315 601 4.12E-67 T 11-10-2018 IPR029041 FAD-linked oxidoreductase-like AFK25_03315 d3295ccce2e33016c4bb71e8fc0f71b4 615 SUPERFAMILY SSF82282 3 360 6.02E-103 T 11-10-2018 IPR036589 Homocysteine-binding domain superfamily Reactome: R-HSA-1614635 AFK25_08705 8df009d8670f41d237b4bad0cfd6c9c6 864 SUPERFAMILY SSF56601 235 684 8.64E-110 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFK25_08705 8df009d8670f41d237b4bad0cfd6c9c6 864 Gene3D G3DSA:3.90.1310.20 73 530 4.6E-225 T 11-10-2018 AFK25_08705 8df009d8670f41d237b4bad0cfd6c9c6 864 Gene3D G3DSA:3.40.710.10 318 645 4.6E-225 T 11-10-2018 AFK25_08705 8df009d8670f41d237b4bad0cfd6c9c6 864 TIGRFAM TIGR02074 PBP_1a_fam: penicillin-binding protein, 1A family 88 633 1.2E-189 T 11-10-2018 AFK25_08705 8df009d8670f41d237b4bad0cfd6c9c6 864 Pfam PF00905 Penicillin binding protein transpeptidase domain 346 628 4.0E-50 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFK25_08705 8df009d8670f41d237b4bad0cfd6c9c6 864 Pfam PF00912 Transglycosylase 78 253 1.7E-64 T 11-10-2018 IPR001264 Glycosyl transferase, family 51 KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_08705 8df009d8670f41d237b4bad0cfd6c9c6 864 SUPERFAMILY SSF53955 67 279 1.66E-75 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily AFK25_08705 8df009d8670f41d237b4bad0cfd6c9c6 864 Gene3D G3DSA:1.10.3810.10 88 281 4.6E-225 T 11-10-2018 IPR036950 Penicillin binding protein transglycosylase domain KEGG: 00550+2.4.1.129|MetaCyc: PWY-5265|MetaCyc: PWY-6385|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_11665 e5edc5c21af3ace35a24b24453c93e28 1073 Pfam PF07733 Bacterial DNA polymerase III alpha subunit 283 683 2.0E-159 T 11-10-2018 IPR011708 Bacterial DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_11665 e5edc5c21af3ace35a24b24453c93e28 1073 Pfam PF02811 PHP domain 5 165 2.9E-30 T 11-10-2018 IPR004013 PHP domain GO:0003824 AFK25_11665 e5edc5c21af3ace35a24b24453c93e28 1073 Gene3D G3DSA:3.30.1900.20 394 516 8.5E-6 T 11-10-2018 AFK25_11665 e5edc5c21af3ace35a24b24453c93e28 1073 Pfam PF14579 Helix-hairpin-helix motif 757 843 2.6E-20 T 11-10-2018 IPR029460 DNA polymerase, helix-hairpin-helix motif KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_11665 e5edc5c21af3ace35a24b24453c93e28 1073 Gene3D G3DSA:1.10.100.20 413 470 8.5E-6 T 11-10-2018 AFK25_11665 e5edc5c21af3ace35a24b24453c93e28 1073 SMART SM00481 4 71 1.1E-20 T 11-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal AFK25_11665 e5edc5c21af3ace35a24b24453c93e28 1073 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 3 439 1.5E-148 T 11-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_11665 e5edc5c21af3ace35a24b24453c93e28 1073 TIGRFAM TIGR00594 polc: DNA polymerase III, alpha subunit 451 956 5.7E-173 T 11-10-2018 IPR004805 DNA polymerase III, alpha subunit GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AFK25_11665 e5edc5c21af3ace35a24b24453c93e28 1073 SUPERFAMILY SSF89550 10 255 6.08E-14 T 11-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFK25_11665 e5edc5c21af3ace35a24b24453c93e28 1073 Gene3D G3DSA:1.10.150.870 727 828 5.5E-7 T 11-10-2018 AFK25_11665 e5edc5c21af3ace35a24b24453c93e28 1073 Gene3D G3DSA:3.20.20.140 1 262 4.7E-78 T 11-10-2018 AFK25_09980 b43620ae6da15ab845dc72857230b7a3 364 Hamap MF_00259 Aminomethyltransferase [gcvT]. 1 362 49.449 T 11-10-2018 IPR022903 Glycine cleavage system T protein, bacteria GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 AFK25_09980 b43620ae6da15ab845dc72857230b7a3 364 Gene3D G3DSA:4.10.1250.10 237 279 7.9E-18 T 11-10-2018 AFK25_09980 b43620ae6da15ab845dc72857230b7a3 364 SUPERFAMILY SSF103025 2 281 2.35E-106 T 11-10-2018 AFK25_09980 b43620ae6da15ab845dc72857230b7a3 364 TIGRFAM TIGR00528 gcvT: glycine cleavage system T protein 2 362 2.6E-150 T 11-10-2018 IPR006223 Glycine cleavage system T protein GO:0004047|GO:0006546 KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 AFK25_09980 b43620ae6da15ab845dc72857230b7a3 364 Pfam PF01571 Aminomethyltransferase folate-binding domain 10 257 2.0E-99 T 11-10-2018 IPR006222 Aminomethyltransferase, folate-binding domain AFK25_09980 b43620ae6da15ab845dc72857230b7a3 364 PIRSF PIRSF006487 1 364 8.6E-108 T 11-10-2018 IPR028896 Aminomethyltransferase-like KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10|Reactome: R-HSA-6783984 AFK25_09980 b43620ae6da15ab845dc72857230b7a3 364 Gene3D G3DSA:2.40.30.110 280 362 5.2E-34 T 11-10-2018 AFK25_09980 b43620ae6da15ab845dc72857230b7a3 364 SUPERFAMILY SSF101790 273 362 4.25E-28 T 11-10-2018 IPR029043 Glycine cleavage T-protein/YgfZ, C-terminal AFK25_09980 b43620ae6da15ab845dc72857230b7a3 364 Pfam PF08669 Glycine cleavage T-protein C-terminal barrel domain 266 356 1.6E-29 T 11-10-2018 IPR013977 Glycine cleavage T-protein, C-terminal barrel domain KEGG: 00260+2.1.2.10|KEGG: 00670+2.1.2.10 AFK25_09980 b43620ae6da15ab845dc72857230b7a3 364 Gene3D G3DSA:3.30.70.1400 51 136 9.2E-95 T 11-10-2018 AFK25_09980 b43620ae6da15ab845dc72857230b7a3 364 Gene3D G3DSA:3.30.1360.120 4 235 9.2E-95 T 11-10-2018 IPR027266 GTP-binding protein TrmE/Glycine cleavage system T protein, domain 1 GO:0005515 AFK25_05565 061eeff6191c089b84bf2d7c345d107d 174 Hamap MF_00014 Ribosome maturation factor RimM [rimM]. 6 171 24.229 T 11-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 AFK25_05565 061eeff6191c089b84bf2d7c345d107d 174 SUPERFAMILY SSF50346 101 171 2.75E-21 T 11-10-2018 IPR011033 PRC-barrel-like superfamily AFK25_05565 061eeff6191c089b84bf2d7c345d107d 174 Pfam PF01782 RimM N-terminal domain 9 92 8.3E-23 T 11-10-2018 IPR002676 RimM, N-terminal GO:0006364 AFK25_05565 061eeff6191c089b84bf2d7c345d107d 174 Gene3D G3DSA:2.40.30.60 7 93 6.3E-20 T 11-10-2018 IPR036976 RimM, N-terminal domain superfamily GO:0006364 AFK25_05565 061eeff6191c089b84bf2d7c345d107d 174 Gene3D G3DSA:2.30.30.240 96 174 6.6E-24 T 11-10-2018 AFK25_05565 061eeff6191c089b84bf2d7c345d107d 174 Pfam PF05239 PRC-barrel domain 98 172 2.5E-15 T 11-10-2018 IPR027275 PRC-barrel domain AFK25_05565 061eeff6191c089b84bf2d7c345d107d 174 TIGRFAM TIGR02273 16S_RimM: 16S rRNA processing protein RimM 6 171 1.4E-53 T 11-10-2018 IPR011961 16S rRNA processing protein RimM GO:0005840|GO:0006364|GO:0043022 AFK25_05565 061eeff6191c089b84bf2d7c345d107d 174 SUPERFAMILY SSF50447 5 93 8.36E-22 T 11-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AFK25_14220 0868f6a4aa366450006a5b5565c239c6 313 SUPERFAMILY SSF46785 16 53 7.07E-6 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_14220 0868f6a4aa366450006a5b5565c239c6 313 Gene3D G3DSA:1.10.10.60 1 52 8.1E-22 T 11-10-2018 AFK25_14220 0868f6a4aa366450006a5b5565c239c6 313 SUPERFAMILY SSF100950 56 311 4.42E-77 T 11-10-2018 IPR037171 NagB/RpiA transferase-like AFK25_14220 0868f6a4aa366450006a5b5565c239c6 313 Pfam PF13545 Crp-like helix-turn-helix domain 19 57 2.4E-7 T 11-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AFK25_14220 0868f6a4aa366450006a5b5565c239c6 313 Pfam PF04198 Putative sugar-binding domain 57 311 7.3E-74 T 11-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 AFK25_14220 0868f6a4aa366450006a5b5565c239c6 313 Gene3D G3DSA:3.40.50.1360 54 313 3.8E-87 T 11-10-2018 AFK25_04760 540c2ccaf47746187728c9c187eb8151 525 Gene3D G3DSA:3.30.70.270 110 272 2.6E-36 T 11-10-2018 AFK25_04760 540c2ccaf47746187728c9c187eb8151 525 Pfam PF00563 EAL domain 280 514 1.8E-79 T 11-10-2018 IPR001633 EAL domain AFK25_04760 540c2ccaf47746187728c9c187eb8151 525 SMART SM00267 98 263 1.0E-23 T 11-10-2018 IPR000160 GGDEF domain AFK25_04760 540c2ccaf47746187728c9c187eb8151 525 SMART SM00052 273 519 6.7E-129 T 11-10-2018 IPR001633 EAL domain AFK25_04760 540c2ccaf47746187728c9c187eb8151 525 TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain 111 260 1.5E-17 T 11-10-2018 IPR000160 GGDEF domain AFK25_04760 540c2ccaf47746187728c9c187eb8151 525 Gene3D G3DSA:3.20.20.450 274 525 4.6E-108 T 11-10-2018 IPR035919 EAL domain superfamily AFK25_04760 540c2ccaf47746187728c9c187eb8151 525 SUPERFAMILY SSF141868 279 524 3.4E-97 T 11-10-2018 IPR035919 EAL domain superfamily AFK25_04760 540c2ccaf47746187728c9c187eb8151 525 SUPERFAMILY SSF55073 114 265 5.34E-36 T 11-10-2018 IPR029787 Nucleotide cyclase AFK25_04760 540c2ccaf47746187728c9c187eb8151 525 Pfam PF00990 Diguanylate cyclase, GGDEF domain 111 258 4.9E-27 T 11-10-2018 IPR000160 GGDEF domain AFK25_14200 47b3f6a131ebaa1137d710a5743849cd 131 SUPERFAMILY SSF53927 2 130 6.97E-49 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFK25_14200 47b3f6a131ebaa1137d710a5743849cd 131 Gene3D G3DSA:3.40.140.10 1 131 2.0E-59 T 11-10-2018 AFK25_14200 47b3f6a131ebaa1137d710a5743849cd 131 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 3 99 9.5E-17 T 11-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain AFK25_14200 47b3f6a131ebaa1137d710a5743849cd 131 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 93 - T 11-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 AFK25_14200 47b3f6a131ebaa1137d710a5743849cd 131 TIGRFAM TIGR01354 cyt_deam_tetra: cytidine deaminase 5 130 6.1E-47 T 11-10-2018 IPR006262 Cytidine deaminase, homotetrameric GO:0004126|GO:0008270|GO:0009972 KEGG: 00240+3.5.4.5|KEGG: 00983+3.5.4.5|MetaCyc: PWY-6556|MetaCyc: PWY-7181|MetaCyc: PWY-7193|MetaCyc: PWY-7199|Reactome: R-HSA-6798695|Reactome: R-HSA-73614 AFK25_09095 bcd0201fbe4eafcccb94ca24047ced07 78 ProDom PD059966 COTJA SPORE PROTEIN-RELATED COAT-ASSOCIATED COTJAA JA 6 70 1.0E-19 T 11-10-2018 IPR020256 Spore coat protein CotJA AFK25_09095 bcd0201fbe4eafcccb94ca24047ced07 78 Pfam PF11007 Spore coat associated protein JA (CotJA) 30 63 4.4E-12 T 11-10-2018 IPR020256 Spore coat protein CotJA AFK25_05430 8237045edc5cd2b735c886e22b831eb0 448 Gene3D G3DSA:1.10.940.10 1 141 3.6E-37 T 11-10-2018 IPR035926 NusB-like superfamily AFK25_05430 8237045edc5cd2b735c886e22b831eb0 448 ProSitePatterns PS01153 NOL1/NOP2/sun family signature. 321 332 - T 11-10-2018 IPR018314 Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site GO:0003723|GO:0008168 AFK25_05430 8237045edc5cd2b735c886e22b831eb0 448 TIGRFAM TIGR00563 rsmB: 16S rRNA (cytosine(967)-C(5))-methyltransferase 7 445 4.0E-153 T 11-10-2018 IPR004573 rRNA small subunit methyltransferase B GO:0006364|GO:0008649 AFK25_05430 8237045edc5cd2b735c886e22b831eb0 448 SUPERFAMILY SSF48013 3 127 1.23E-35 T 11-10-2018 IPR035926 NusB-like superfamily AFK25_05430 8237045edc5cd2b735c886e22b831eb0 448 SUPERFAMILY SSF53335 136 444 3.04E-77 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_05430 8237045edc5cd2b735c886e22b831eb0 448 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 254 264 5.3E-32 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFK25_05430 8237045edc5cd2b735c886e22b831eb0 448 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 426 443 5.3E-32 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFK25_05430 8237045edc5cd2b735c886e22b831eb0 448 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 225 239 5.3E-32 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFK25_05430 8237045edc5cd2b735c886e22b831eb0 448 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 372 388 5.3E-32 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFK25_05430 8237045edc5cd2b735c886e22b831eb0 448 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 322 334 5.3E-32 T 11-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AFK25_05430 8237045edc5cd2b735c886e22b831eb0 448 Pfam PF01189 16S rRNA methyltransferase RsmB/F 242 442 1.8E-67 T 11-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 AFK25_05430 8237045edc5cd2b735c886e22b831eb0 448 Gene3D G3DSA:3.40.50.150 143 443 2.1E-89 T 11-10-2018 AFK25_05430 8237045edc5cd2b735c886e22b831eb0 448 Pfam PF01029 NusB family 5 126 3.3E-29 T 11-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 AFK25_12505 e5a282c40d7c2b0f5c15cc061434886a 121 SUPERFAMILY SSF47413 1 67 6.7E-19 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFK25_12505 e5a282c40d7c2b0f5c15cc061434886a 121 SMART SM00530 7 62 2.3E-14 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFK25_12505 e5a282c40d7c2b0f5c15cc061434886a 121 Pfam PF01381 Helix-turn-helix 8 62 1.0E-15 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFK25_12505 e5a282c40d7c2b0f5c15cc061434886a 121 Gene3D G3DSA:1.10.260.40 4 120 4.6E-21 T 11-10-2018 AFK25_10350 5629d3b28fe2c595cd9444f3fa56d7b8 147 Gene3D G3DSA:1.10.10.410 91 147 1.1E-27 T 11-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal AFK25_10350 5629d3b28fe2c595cd9444f3fa56d7b8 147 SUPERFAMILY SSF89095 1 147 7.32E-46 T 11-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 AFK25_10350 5629d3b28fe2c595cd9444f3fa56d7b8 147 Gene3D G3DSA:1.10.1510.10 1 90 2.4E-31 T 11-10-2018 AFK25_10350 5629d3b28fe2c595cd9444f3fa56d7b8 147 Pfam PF09424 Yqey-like protein 5 146 1.9E-57 T 11-10-2018 IPR019004 Uncharacterised protein YqeY/AIM41 AFK25_00220 99b053e4f709d93fc937f9ab757349e0 255 PIRSF PIRSF005902 1 255 1.4E-94 T 11-10-2018 IPR001130 TatD family GO:0016788 AFK25_00220 99b053e4f709d93fc937f9ab757349e0 255 ProSitePatterns PS01091 TatD deoxyribonuclease family signature 3. 189 205 - T 11-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 AFK25_00220 99b053e4f709d93fc937f9ab757349e0 255 ProSitePatterns PS01137 TatD deoxyribonuclease family signature 1. 2 10 - T 11-10-2018 IPR018228 Deoxyribonuclease, TatD-related, conserved site GO:0016888 AFK25_00220 99b053e4f709d93fc937f9ab757349e0 255 Pfam PF01026 TatD related DNase 3 253 9.2E-92 T 11-10-2018 IPR001130 TatD family GO:0016788 AFK25_00220 99b053e4f709d93fc937f9ab757349e0 255 SUPERFAMILY SSF51556 1 254 6.82E-102 T 11-10-2018 IPR032466 Metal-dependent hydrolase AFK25_00220 99b053e4f709d93fc937f9ab757349e0 255 Gene3D G3DSA:3.20.20.140 1 255 5.9E-115 T 11-10-2018 AFK25_00220 99b053e4f709d93fc937f9ab757349e0 255 TIGRFAM TIGR00010 TIGR00010: hydrolase, TatD family 2 253 5.4E-103 T 11-10-2018 IPR015991 Uncharacterised hydrolase TatD-type GO:0004536 AFK25_09680 dac67943564a5539a4487badf4351890 309 SUPERFAMILY SSF56281 2 303 1.14E-85 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_09680 dac67943564a5539a4487badf4351890 309 Pfam PF00753 Metallo-beta-lactamase superfamily 26 87 2.7E-9 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_09680 dac67943564a5539a4487badf4351890 309 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 2 303 2.4E-115 T 11-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 AFK25_09680 dac67943564a5539a4487badf4351890 309 Hamap MF_01818 Ribonuclease BN [rbn]. 1 304 41.61 T 11-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 AFK25_09680 dac67943564a5539a4487badf4351890 309 Gene3D G3DSA:3.60.15.10 1 304 1.1E-105 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_09680 dac67943564a5539a4487badf4351890 309 Pfam PF12706 Beta-lactamase superfamily domain 201 270 2.5E-8 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_03255 df7feed6a8ff94fe78aa1e9729a51524 215 Pfam PF02570 Precorrin-8X methylmutase 16 209 7.9E-80 T 11-10-2018 IPR003722 Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC GO:0009236|GO:0016993 AFK25_03255 df7feed6a8ff94fe78aa1e9729a51524 215 SUPERFAMILY SSF63965 10 212 1.83E-73 T 11-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 AFK25_03255 df7feed6a8ff94fe78aa1e9729a51524 215 Gene3D G3DSA:3.40.50.10230 5 215 1.3E-84 T 11-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 AFK25_03530 7d014c718cb427d9f590bc6f6107dbec 203 SUPERFAMILY SSF53955 76 197 3.38E-51 T 11-10-2018 IPR023346 Lysozyme-like domain superfamily AFK25_03530 7d014c718cb427d9f590bc6f6107dbec 203 Pfam PF01464 Transglycosylase SLT domain 81 185 7.1E-35 T 11-10-2018 IPR008258 Transglycosylase SLT domain 1 AFK25_03530 7d014c718cb427d9f590bc6f6107dbec 203 Gene3D G3DSA:1.10.530.10 38 201 3.4E-54 T 11-10-2018 AFK25_03530 7d014c718cb427d9f590bc6f6107dbec 203 ProSitePatterns PS00922 Prokaryotic transglycosylases signature. 98 126 - T 11-10-2018 IPR000189 Prokaryotic transglycosylase, active site GO:0000270|GO:0008933|GO:0016020 AFK25_05440 3286920eec1afd7b983f86f50be26413 249 SUPERFAMILY SSF81606 2 242 1.26E-65 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFK25_05440 3286920eec1afd7b983f86f50be26413 249 Pfam PF13672 Protein phosphatase 2C 14 209 9.3E-18 T 11-10-2018 AFK25_05440 3286920eec1afd7b983f86f50be26413 249 Gene3D G3DSA:3.60.40.10 1 244 2.0E-72 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFK25_05440 3286920eec1afd7b983f86f50be26413 249 SMART SM00331 7 242 3.8E-50 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFK25_05440 3286920eec1afd7b983f86f50be26413 249 SMART SM00332 1 240 1.0E-28 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFK25_10960 cb40d220ca1eff2d84fa925395faf1f5 286 PIRSF PIRSF038471 1 286 1.9E-71 T 11-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 AFK25_10960 cb40d220ca1eff2d84fa925395faf1f5 286 TIGRFAM TIGR00219 mreC: rod shape-determining protein MreC 6 283 2.1E-61 T 11-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 AFK25_10960 cb40d220ca1eff2d84fa925395faf1f5 286 Pfam PF04085 rod shape-determining protein MreC 123 274 1.4E-45 T 11-10-2018 IPR007221 Rod shape-determining protein MreC GO:0008360 AFK25_10960 cb40d220ca1eff2d84fa925395faf1f5 286 Gene3D G3DSA:2.40.10.350 186 261 7.5E-32 T 11-10-2018 AFK25_10960 cb40d220ca1eff2d84fa925395faf1f5 286 Gene3D G3DSA:2.40.10.340 113 185 1.1E-24 T 11-10-2018 AFK25_09925 73b81240ec3cd1a854986b9ce70bd6f3 187 Pfam PF11085 Conserved membrane protein YqhR 21 182 4.4E-77 T 11-10-2018 IPR024563 Uncharacterised protein family YqhR AFK25_09925 73b81240ec3cd1a854986b9ce70bd6f3 187 ProDom PD101610 MEMBRANE YQHR BH2802 TRANSMEMBRANE IG 25 179 4.0E-50 T 11-10-2018 IPR024563 Uncharacterised protein family YqhR AFK25_13530 b89f9ee72d25e924b192a239002c531f 137 SMART SM00530 8 63 2.2E-16 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFK25_13530 b89f9ee72d25e924b192a239002c531f 137 Gene3D G3DSA:1.10.260.40 1 67 3.9E-23 T 11-10-2018 AFK25_13530 b89f9ee72d25e924b192a239002c531f 137 SUPERFAMILY SSF47413 3 68 1.98E-18 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFK25_13530 b89f9ee72d25e924b192a239002c531f 137 Pfam PF01381 Helix-turn-helix 9 63 5.4E-16 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFK25_11170 bb0cd12ad409eae92f3bec3cb8bb54ff 369 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 4 351 1.5E-141 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFK25_11170 bb0cd12ad409eae92f3bec3cb8bb54ff 369 Gene3D G3DSA:3.40.718.10 1 369 9.1E-157 T 11-10-2018 AFK25_11170 bb0cd12ad409eae92f3bec3cb8bb54ff 369 SMART SM01329 3 351 5.9E-208 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFK25_11170 bb0cd12ad409eae92f3bec3cb8bb54ff 369 Hamap MF_01033 3-isopropylmalate dehydrogenase [leuB]. 2 355 50.812 T 11-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 AFK25_11170 bb0cd12ad409eae92f3bec3cb8bb54ff 369 TIGRFAM TIGR00169 leuB: 3-isopropylmalate dehydrogenase 3 350 2.9E-163 T 11-10-2018 IPR004429 Isopropylmalate dehydrogenase GO:0003862|GO:0005737|GO:0009098|GO:0055114 KEGG: 00290+1.1.1.85|KEGG: 00660+1.1.1.85|MetaCyc: PWY-7396 AFK25_11170 bb0cd12ad409eae92f3bec3cb8bb54ff 369 SUPERFAMILY SSF53659 2 354 8.64E-126 T 11-10-2018 AFK25_11170 bb0cd12ad409eae92f3bec3cb8bb54ff 369 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 242 261 - T 11-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 AFK25_03035 39a6e0eda2119db5a96b1b9c5e2e725b 1209 SUPERFAMILY SSF52540 4 896 1.15E-119 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_03035 39a6e0eda2119db5a96b1b9c5e2e725b 1209 Gene3D G3DSA:3.40.50.300 476 757 2.6E-58 T 11-10-2018 AFK25_03035 39a6e0eda2119db5a96b1b9c5e2e725b 1209 Gene3D G3DSA:3.40.50.300 758 953 8.5E-46 T 11-10-2018 AFK25_03035 39a6e0eda2119db5a96b1b9c5e2e725b 1209 Hamap MF_01451 ATP-dependent helicase/nuclease subunit A [addA]. 8 1206 20.128 T 11-10-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 AFK25_03035 39a6e0eda2119db5a96b1b9c5e2e725b 1209 TIGRFAM TIGR02785 addA_Gpos: helicase-exonuclease AddAB, AddA subunit 10 1204 0.0 T 11-10-2018 IPR014152 DNA helicase subunit AddA GO:0004003|GO:0006302 AFK25_03035 39a6e0eda2119db5a96b1b9c5e2e725b 1209 Gene3D G3DSA:3.40.50.300 229 474 5.5E-33 T 11-10-2018 AFK25_03035 39a6e0eda2119db5a96b1b9c5e2e725b 1209 Gene3D G3DSA:3.40.50.300 4 192 2.7E-43 T 11-10-2018 AFK25_03035 39a6e0eda2119db5a96b1b9c5e2e725b 1209 Pfam PF13361 UvrD-like helicase C-terminal domain 473 882 9.5E-41 T 11-10-2018 IPR014017 UvrD-like DNA helicase, C-terminal GO:0005524|GO:0016787 AFK25_03035 39a6e0eda2119db5a96b1b9c5e2e725b 1209 SUPERFAMILY SSF52980 1005 1199 8.58E-36 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFK25_03035 39a6e0eda2119db5a96b1b9c5e2e725b 1209 Gene3D G3DSA:3.90.320.10 982 1205 4.2E-74 T 11-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal AFK25_03035 39a6e0eda2119db5a96b1b9c5e2e725b 1209 Pfam PF00580 UvrD/REP helicase N-terminal domain 11 463 2.5E-88 T 11-10-2018 IPR034739 UvrD/AddA helicase, N-terminal GO:0005524 AFK25_03035 39a6e0eda2119db5a96b1b9c5e2e725b 1209 Pfam PF12705 PD-(D/E)XK nuclease superfamily 1040 1189 1.4E-12 T 11-10-2018 IPR038726 PD-(D/E)XK endonuclease-like domain, AddAB-type AFK25_05045 b5c46e8cb59029d5d1acab6b7f94820a 152 Pfam PF04238 Protein of unknown function (DUF420) 5 133 1.9E-39 T 11-10-2018 IPR007352 Protein of unknown function DUF420 AFK25_14315 70fd03f17b344c6b886579896920b2d5 226 Gene3D G3DSA:3.40.50.300 1 222 2.1E-67 T 11-10-2018 AFK25_14315 70fd03f17b344c6b886579896920b2d5 226 Pfam PF00005 ABC transporter 22 170 4.1E-35 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_14315 70fd03f17b344c6b886579896920b2d5 226 SMART SM00382 31 218 7.4E-15 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_14315 70fd03f17b344c6b886579896920b2d5 226 SUPERFAMILY SSF52540 2 220 1.54E-67 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_14315 70fd03f17b344c6b886579896920b2d5 226 ProSitePatterns PS00211 ABC transporters family signature. 143 157 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_01480 5dd58e2f2215f13210f032ef8cc54afb 223 Gene3D G3DSA:1.10.10.10 125 223 2.8E-31 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_01480 5dd58e2f2215f13210f032ef8cc54afb 223 Gene3D G3DSA:3.40.50.2300 1 124 4.6E-36 T 11-10-2018 AFK25_01480 5dd58e2f2215f13210f032ef8cc54afb 223 SMART SM00448 1 113 1.5E-40 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_01480 5dd58e2f2215f13210f032ef8cc54afb 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 147 220 3.5E-25 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFK25_01480 5dd58e2f2215f13210f032ef8cc54afb 223 SUPERFAMILY SSF52172 1 126 4.27E-37 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_01480 5dd58e2f2215f13210f032ef8cc54afb 223 SMART SM00862 147 221 4.8E-24 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFK25_01480 5dd58e2f2215f13210f032ef8cc54afb 223 SUPERFAMILY SSF46894 124 221 7.37E-28 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFK25_01480 5dd58e2f2215f13210f032ef8cc54afb 223 Pfam PF00072 Response regulator receiver domain 3 113 4.1E-28 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_14190 2baeedae2eee8f0b3506d0033074bdeb 271 Gene3D G3DSA:3.90.550.10 2 233 1.6E-37 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_14190 2baeedae2eee8f0b3506d0033074bdeb 271 Pfam PF00535 Glycosyl transferase family 2 4 162 8.2E-26 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFK25_14190 2baeedae2eee8f0b3506d0033074bdeb 271 SUPERFAMILY SSF53448 3 216 3.88E-41 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_00640 27fcc6a4d18c75f1c861eb2637224740 144 SUPERFAMILY SSF54686 1 137 1.7E-59 T 11-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 AFK25_00640 27fcc6a4d18c75f1c861eb2637224740 144 Pfam PF00252 Ribosomal protein L16p/L10e 4 132 2.7E-53 T 11-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 AFK25_00640 27fcc6a4d18c75f1c861eb2637224740 144 Gene3D G3DSA:3.90.1170.10 1 143 1.7E-57 T 11-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 AFK25_00640 27fcc6a4d18c75f1c861eb2637224740 144 ProSitePatterns PS00586 Ribosomal protein L16 signature 1. 59 70 - T 11-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00640 27fcc6a4d18c75f1c861eb2637224740 144 ProSitePatterns PS00701 Ribosomal protein L16 signature 2. 82 93 - T 11-10-2018 IPR020798 Ribosomal protein L16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00640 27fcc6a4d18c75f1c861eb2637224740 144 PRINTS PR00060 Ribosomal protein L16 signature 24 36 1.2E-41 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00640 27fcc6a4d18c75f1c861eb2637224740 144 PRINTS PR00060 Ribosomal protein L16 signature 58 87 1.2E-41 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00640 27fcc6a4d18c75f1c861eb2637224740 144 PRINTS PR00060 Ribosomal protein L16 signature 42 53 1.2E-41 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00640 27fcc6a4d18c75f1c861eb2637224740 144 PRINTS PR00060 Ribosomal protein L16 signature 88 117 1.2E-41 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00640 27fcc6a4d18c75f1c861eb2637224740 144 TIGRFAM TIGR01164 rplP_bact: ribosomal protein uL16 2 127 1.2E-64 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00640 27fcc6a4d18c75f1c861eb2637224740 144 Hamap MF_01342 50S ribosomal protein L16 [rplP]. 1 134 41.88 T 11-10-2018 IPR000114 Ribosomal protein L16 GO:0003735|GO:0006412|GO:0019843 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_11610 f3964ba87275306630db23ee7da3b0aa 424 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 307 326 - T 11-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 AFK25_11610 f3964ba87275306630db23ee7da3b0aa 424 SUPERFAMILY SSF53659 3 422 1.86E-143 T 11-10-2018 AFK25_11610 f3964ba87275306630db23ee7da3b0aa 424 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 22 417 3.3E-124 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFK25_11610 f3964ba87275306630db23ee7da3b0aa 424 Gene3D G3DSA:3.40.718.10 1 423 2.7E-184 T 11-10-2018 AFK25_11610 f3964ba87275306630db23ee7da3b0aa 424 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 3 422 3.1E-224 T 11-10-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 AFK25_11610 f3964ba87275306630db23ee7da3b0aa 424 SMART SM01329 21 418 1.0E-191 T 11-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AFK25_06435 8845a5af0e816e754af8967604f4742f 195 Pfam PF01476 LysM domain 29 71 1.9E-10 T 11-10-2018 IPR018392 LysM domain AFK25_06435 8845a5af0e816e754af8967604f4742f 195 Gene3D G3DSA:3.10.350.10 18 78 5.5E-14 T 11-10-2018 IPR036779 LysM domain superfamily AFK25_06435 8845a5af0e816e754af8967604f4742f 195 SUPERFAMILY SSF54106 27 72 3.4E-11 T 11-10-2018 AFK25_06435 8845a5af0e816e754af8967604f4742f 195 SMART SM00257 28 71 9.7E-12 T 11-10-2018 IPR018392 LysM domain AFK25_06435 8845a5af0e816e754af8967604f4742f 195 Pfam PF07486 Cell Wall Hydrolase 92 193 4.5E-24 T 11-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 AFK25_06435 8845a5af0e816e754af8967604f4742f 195 Gene3D G3DSA:2.40.10.420 162 195 5.8E-15 T 11-10-2018 AFK25_06435 8845a5af0e816e754af8967604f4742f 195 Gene3D G3DSA:1.10.10.2520 79 158 3.6E-28 T 11-10-2018 AFK25_13070 02afee57d38f9928998d6931f8907e55 74 Pfam PF09964 Uncharacterized protein conserved in bacteria (DUF2198) 2 72 4.0E-35 T 11-10-2018 IPR019242 Protein of unknown function DUF2198 AFK25_08290 5f63e29b2f185e4381fb246e575b7ac6 459 Gene3D G3DSA:1.20.1740.10 4 458 3.0E-77 T 11-10-2018 AFK25_08290 5f63e29b2f185e4381fb246e575b7ac6 459 PIRSF PIRSF006060 1 457 4.3E-90 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFK25_08290 5f63e29b2f185e4381fb246e575b7ac6 459 Pfam PF13520 Amino acid permease 12 423 5.0E-48 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFK25_08005 e4b2de5fb27d4e095dd265714c99860f 117 Gene3D G3DSA:3.40.250.10 21 103 5.0E-6 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_08005 e4b2de5fb27d4e095dd265714c99860f 117 SUPERFAMILY SSF52821 5 97 8.51E-8 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_10930 15bfb5edb89e11d9659406c474d53770 102 Pfam PF00829 Ribosomal prokaryotic L21 protein 1 100 1.3E-42 T 11-10-2018 IPR028909 Ribosomal protein L21-like GO:0005840 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10930 15bfb5edb89e11d9659406c474d53770 102 Hamap MF_01363 50S ribosomal protein L21 [rplU]. 1 102 27.865 T 11-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10930 15bfb5edb89e11d9659406c474d53770 102 TIGRFAM TIGR00061 L21: ribosomal protein bL21 2 101 4.3E-42 T 11-10-2018 IPR001787 Ribosomal protein L21 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_10930 15bfb5edb89e11d9659406c474d53770 102 ProSitePatterns PS01169 Ribosomal protein L21 signature. 71 93 - T 11-10-2018 IPR018258 Ribosomal protein L21, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_10930 15bfb5edb89e11d9659406c474d53770 102 SUPERFAMILY SSF141091 1 101 1.57E-40 T 11-10-2018 IPR036164 L21-like superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_14435 dbb303c67eaf73bd8501fa359ef856e0 265 SUPERFAMILY SSF161098 10 254 1.03E-46 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_14435 dbb303c67eaf73bd8501fa359ef856e0 265 Gene3D G3DSA:1.10.3720.10 4 261 7.7E-45 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_14435 dbb303c67eaf73bd8501fa359ef856e0 265 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 255 1.4E-8 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_12250 b631413c692736bb326c170f1d5ad443 449 PIRSF PIRSF006446 1 448 2.6E-174 T 11-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 AFK25_12250 b631413c692736bb326c170f1d5ad443 449 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 7 434 3.1E-173 T 11-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 AFK25_01865 83308205e79524bd43a1ec464ae84178 185 Gene3D G3DSA:3.40.630.30 1 183 1.4E-20 T 11-10-2018 AFK25_01865 83308205e79524bd43a1ec464ae84178 185 SUPERFAMILY SSF55729 2 134 2.59E-20 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFK25_01865 83308205e79524bd43a1ec464ae84178 185 Pfam PF13302 Acetyltransferase (GNAT) domain 6 132 9.3E-13 T 11-10-2018 IPR000182 GNAT domain AFK25_11400 3c9aaa18ea8c3fca7f58f105d9ce4c30 441 SUPERFAMILY SSF51658 3 437 7.88E-183 T 11-10-2018 IPR036237 Xylose isomerase-like superfamily AFK25_11400 3c9aaa18ea8c3fca7f58f105d9ce4c30 441 Hamap MF_00455 Xylose isomerase [xylA]. 10 434 56.424 T 11-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFK25_11400 3c9aaa18ea8c3fca7f58f105d9ce4c30 441 Gene3D G3DSA:3.20.20.150 2 441 6.5E-196 T 11-10-2018 AFK25_11400 3c9aaa18ea8c3fca7f58f105d9ce4c30 441 Pfam PF01261 Xylose isomerase-like TIM barrel 146 282 3.2E-7 T 11-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AFK25_11400 3c9aaa18ea8c3fca7f58f105d9ce4c30 441 PRINTS PR00688 Xylose isomerase signature 331 342 1.2E-102 T 11-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFK25_11400 3c9aaa18ea8c3fca7f58f105d9ce4c30 441 PRINTS PR00688 Xylose isomerase signature 90 112 1.2E-102 T 11-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFK25_11400 3c9aaa18ea8c3fca7f58f105d9ce4c30 441 PRINTS PR00688 Xylose isomerase signature 131 151 1.2E-102 T 11-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFK25_11400 3c9aaa18ea8c3fca7f58f105d9ce4c30 441 PRINTS PR00688 Xylose isomerase signature 154 173 1.2E-102 T 11-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFK25_11400 3c9aaa18ea8c3fca7f58f105d9ce4c30 441 PRINTS PR00688 Xylose isomerase signature 178 199 1.2E-102 T 11-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFK25_11400 3c9aaa18ea8c3fca7f58f105d9ce4c30 441 PRINTS PR00688 Xylose isomerase signature 298 309 1.2E-102 T 11-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFK25_11400 3c9aaa18ea8c3fca7f58f105d9ce4c30 441 PRINTS PR00688 Xylose isomerase signature 205 224 1.2E-102 T 11-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFK25_11400 3c9aaa18ea8c3fca7f58f105d9ce4c30 441 PRINTS PR00688 Xylose isomerase signature 269 296 1.2E-102 T 11-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFK25_11400 3c9aaa18ea8c3fca7f58f105d9ce4c30 441 PRINTS PR00688 Xylose isomerase signature 227 251 1.2E-102 T 11-10-2018 IPR001998 Xylose isomerase GO:0005975|GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFK25_11400 3c9aaa18ea8c3fca7f58f105d9ce4c30 441 TIGRFAM TIGR02630 xylose_isom_A: xylose isomerase 3 434 8.1E-226 T 11-10-2018 IPR013452 Xylose isomerase, bacterial-type GO:0009045 KEGG: 00040+5.3.1.5|KEGG: 00051+5.3.1.5 AFK25_04990 596bda956fb9e6d76bb16840669fe91f 96 Hamap MF_01560 UPF0358 protein . 3 93 26.626 T 11-10-2018 IPR009983 Uncharacterised protein family UPF0358 AFK25_04990 596bda956fb9e6d76bb16840669fe91f 96 Pfam PF07408 Protein of unknown function (DUF1507) 10 91 8.4E-41 T 11-10-2018 IPR009983 Uncharacterised protein family UPF0358 AFK25_04990 596bda956fb9e6d76bb16840669fe91f 96 Gene3D G3DSA:1.10.287.750 5 93 6.7E-37 T 11-10-2018 IPR036270 UPF0358 superfamily AFK25_04990 596bda956fb9e6d76bb16840669fe91f 96 SUPERFAMILY SSF140404 7 84 3.4E-36 T 11-10-2018 IPR036270 UPF0358 superfamily AFK25_07195 e3bd4c4841335af390f93edd118a77be 186 Pfam PF09911 Uncharacterized protein conserved in bacteria (DUF2140) 2 183 5.9E-58 T 11-10-2018 IPR018672 Protein of unknown function DUF2140 AFK25_06075 ac9323a93a72d494bd18b2ab2a69848f 956 SMART SM00490 474 553 1.8E-19 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_06075 ac9323a93a72d494bd18b2ab2a69848f 956 SMART SM00487 33 227 2.2E-20 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFK25_06075 ac9323a93a72d494bd18b2ab2a69848f 956 Pfam PF00271 Helicase conserved C-terminal domain 445 553 5.4E-18 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_06075 ac9323a93a72d494bd18b2ab2a69848f 956 SUPERFAMILY SSF52540 155 599 5.32E-42 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_06075 ac9323a93a72d494bd18b2ab2a69848f 956 Gene3D G3DSA:3.40.50.10810 34 297 1.1E-55 T 11-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily AFK25_06075 ac9323a93a72d494bd18b2ab2a69848f 956 Gene3D G3DSA:3.40.50.300 301 660 5.4E-40 T 11-10-2018 AFK25_06075 ac9323a93a72d494bd18b2ab2a69848f 956 Pfam PF00176 SNF2 family N-terminal domain 51 313 5.6E-35 T 11-10-2018 IPR000330 SNF2-related, N-terminal domain GO:0005524 AFK25_06075 ac9323a93a72d494bd18b2ab2a69848f 956 SUPERFAMILY SSF52540 23 261 9.78E-44 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_08680 08b9fd36038060a70f8d79747eda6ce8 140 Pfam PF00011 Hsp20/alpha crystallin family 41 135 1.6E-9 T 11-10-2018 IPR002068 Alpha crystallin/Hsp20 domain AFK25_08680 08b9fd36038060a70f8d79747eda6ce8 140 Gene3D G3DSA:2.60.40.790 1 139 1.3E-22 T 11-10-2018 IPR008978 HSP20-like chaperone AFK25_08680 08b9fd36038060a70f8d79747eda6ce8 140 SUPERFAMILY SSF49764 30 135 2.06E-19 T 11-10-2018 IPR008978 HSP20-like chaperone AFK25_05365 73e1fc12359fce316119d35b58d92ad8 312 PIRSF PIRSF000164 1 303 8.1E-86 T 11-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 AFK25_05365 73e1fc12359fce316119d35b58d92ad8 312 Gene3D G3DSA:3.20.20.70 1 301 8.4E-102 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_05365 73e1fc12359fce316119d35b58d92ad8 312 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 239 259 - T 11-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 AFK25_05365 73e1fc12359fce316119d35b58d92ad8 312 SUPERFAMILY SSF51395 2 300 7.99E-90 T 11-10-2018 AFK25_05365 73e1fc12359fce316119d35b58d92ad8 312 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 40 59 - T 11-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 AFK25_05365 73e1fc12359fce316119d35b58d92ad8 312 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 302 1.6E-124 T 11-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 AFK25_05365 73e1fc12359fce316119d35b58d92ad8 312 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 301 42.217 T 11-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 AFK25_05365 73e1fc12359fce316119d35b58d92ad8 312 Pfam PF01180 Dihydroorotate dehydrogenase 4 286 5.6E-96 T 11-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 AFK25_12700 48c79d22a59169de69e3ffcd72b06ee2 100 SUPERFAMILY SSF102891 1 99 1.09E-34 T 11-10-2018 IPR036493 Hypothetical protein YunC superfamily AFK25_12700 48c79d22a59169de69e3ffcd72b06ee2 100 Pfam PF08827 Domain of unknown function (DUF1805) 37 99 5.7E-25 T 11-10-2018 IPR014931 Protein of unknown function DUF1805 AFK25_12700 48c79d22a59169de69e3ffcd72b06ee2 100 Gene3D G3DSA:3.30.1980.10 1 99 4.4E-24 T 11-10-2018 IPR036493 Hypothetical protein YunC superfamily AFK25_07565 3f1828ce0faa991eee33b0728307739c 471 PRINTS PR00175 Sodium/alanine symporter signature 179 197 8.8E-61 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_07565 3f1828ce0faa991eee33b0728307739c 471 PRINTS PR00175 Sodium/alanine symporter signature 298 316 8.8E-61 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_07565 3f1828ce0faa991eee33b0728307739c 471 PRINTS PR00175 Sodium/alanine symporter signature 403 423 8.8E-61 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_07565 3f1828ce0faa991eee33b0728307739c 471 PRINTS PR00175 Sodium/alanine symporter signature 207 226 8.8E-61 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_07565 3f1828ce0faa991eee33b0728307739c 471 PRINTS PR00175 Sodium/alanine symporter signature 343 365 8.8E-61 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_07565 3f1828ce0faa991eee33b0728307739c 471 PRINTS PR00175 Sodium/alanine symporter signature 89 111 8.8E-61 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_07565 3f1828ce0faa991eee33b0728307739c 471 Pfam PF01235 Sodium:alanine symporter family 54 446 2.2E-162 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_07565 3f1828ce0faa991eee33b0728307739c 471 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 89 104 - T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_07565 3f1828ce0faa991eee33b0728307739c 471 TIGRFAM TIGR00835 agcS: amino acid carrier protein 16 434 3.6E-164 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_14420 71423035ad963cbb64431a07e9c07e20 366 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 8 358 1.8E-78 T 11-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 AFK25_14420 71423035ad963cbb64431a07e9c07e20 366 Pfam PF03845 Spore germination protein 9 325 3.1E-68 T 11-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 AFK25_06645 39d55aabdd78022726555e2ce6269cee 305 SMART SM00046 2 131 4.1E-8 T 11-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 AFK25_06645 39d55aabdd78022726555e2ce6269cee 305 Pfam PF00781 Diacylglycerol kinase catalytic domain 3 117 9.0E-27 T 11-10-2018 IPR001206 Diacylglycerol kinase, catalytic domain GO:0016301 AFK25_06645 39d55aabdd78022726555e2ce6269cee 305 SUPERFAMILY SSF111331 3 300 1.48E-70 T 11-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily AFK25_06645 39d55aabdd78022726555e2ce6269cee 305 Gene3D G3DSA:3.40.50.10330 2 134 2.2E-35 T 11-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 AFK25_06645 39d55aabdd78022726555e2ce6269cee 305 Pfam PF00609 Diacylglycerol kinase accessory domain 139 286 2.5E-7 T 11-10-2018 IPR000756 Diacylglycerol kinase, accessory domain GO:0004143|GO:0007205 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817|Reactome: R-HSA-114508 AFK25_06645 39d55aabdd78022726555e2ce6269cee 305 SMART SM00045 138 287 0.0053 T 11-10-2018 IPR000756 Diacylglycerol kinase, accessory domain GO:0004143|GO:0007205 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817|Reactome: R-HSA-114508 AFK25_06645 39d55aabdd78022726555e2ce6269cee 305 TIGRFAM TIGR00147 TIGR00147: lipid kinase, YegS/Rv2252/BmrU family 4 297 5.7E-55 T 11-10-2018 IPR005218 Diacylglycerol/lipid kinase AFK25_06645 39d55aabdd78022726555e2ce6269cee 305 Gene3D G3DSA:2.60.200.40 135 297 1.3E-42 T 11-10-2018 AFK25_09525 f79e4b80855688d77aaf9e50f06735cf 151 Gene3D G3DSA:3.90.1170.40 1 144 7.4E-53 T 11-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 AFK25_09525 f79e4b80855688d77aaf9e50f06735cf 151 Pfam PF02391 MoaE protein 6 115 2.6E-37 T 11-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 AFK25_09525 f79e4b80855688d77aaf9e50f06735cf 151 SUPERFAMILY SSF54690 2 137 2.09E-47 T 11-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 AFK25_07300 3407d08deac4037a20db07be7c969115 389 Pfam PF02417 Chromate transporter 14 175 2.1E-32 T 11-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 AFK25_07300 3407d08deac4037a20db07be7c969115 389 Pfam PF02417 Chromate transporter 224 386 1.6E-44 T 11-10-2018 IPR003370 Chromate transporter GO:0015109|GO:0015703 AFK25_07300 3407d08deac4037a20db07be7c969115 389 TIGRFAM TIGR00937 2A51: chromate efflux transporter 22 386 8.2E-111 T 11-10-2018 IPR014047 Chromate transporter, long chain AFK25_07300 3407d08deac4037a20db07be7c969115 389 PIRSF PIRSF004810 2 389 1.0E-129 T 11-10-2018 IPR014047 Chromate transporter, long chain AFK25_08865 2a694bfc2bdb16bc4958836df07d55c1 428 Gene3D G3DSA:3.65.10.10 20 228 8.3E-160 T 11-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AFK25_08865 2a694bfc2bdb16bc4958836df07d55c1 428 ProSitePatterns PS00885 EPSP synthase signature 2. 338 356 - T 11-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFK25_08865 2a694bfc2bdb16bc4958836df07d55c1 428 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 12 426 5.3E-135 T 11-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFK25_08865 2a694bfc2bdb16bc4958836df07d55c1 428 PIRSF PIRSF000505 1 428 1.5E-124 T 11-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFK25_08865 2a694bfc2bdb16bc4958836df07d55c1 428 Gene3D G3DSA:3.65.10.10 10 423 8.3E-160 T 11-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AFK25_08865 2a694bfc2bdb16bc4958836df07d55c1 428 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 7 423 3.7E-127 T 11-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 AFK25_08865 2a694bfc2bdb16bc4958836df07d55c1 428 SUPERFAMILY SSF55205 4 426 7.3E-141 T 11-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 AFK25_08865 2a694bfc2bdb16bc4958836df07d55c1 428 ProSitePatterns PS00104 EPSP synthase signature 1. 86 100 - T 11-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFK25_08865 2a694bfc2bdb16bc4958836df07d55c1 428 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 8 428 33.489 T 11-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AFK25_13125 6bbedf874463d64786a103e01406e496 329 ProSitePatterns PS00745 Prokaryotic-type class I peptide chain release factors signature. 205 221 - T 11-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 AFK25_13125 6bbedf874463d64786a103e01406e496 329 SMART SM00937 45 155 1.8E-60 T 11-10-2018 IPR005139 Peptide chain release factor GO:0006415 AFK25_13125 6bbedf874463d64786a103e01406e496 329 Gene3D G3DSA:1.20.58.410 1 76 1.1E-17 T 11-10-2018 AFK25_13125 6bbedf874463d64786a103e01406e496 329 Hamap MF_00094 Peptide chain release factor 2 [prfB]. 1 326 37.977 T 11-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 AFK25_13125 6bbedf874463d64786a103e01406e496 329 SUPERFAMILY SSF75620 1 325 3.01E-138 T 11-10-2018 AFK25_13125 6bbedf874463d64786a103e01406e496 329 Gene3D G3DSA:3.30.160.20 186 281 1.8E-100 T 11-10-2018 AFK25_13125 6bbedf874463d64786a103e01406e496 329 TIGRFAM TIGR00020 prfB: peptide chain release factor 2 1 325 2.7E-167 T 11-10-2018 IPR004374 Peptide chain release factor 2 GO:0005737|GO:0006415|GO:0016149 AFK25_13125 6bbedf874463d64786a103e01406e496 329 Pfam PF00472 RF-1 domain 188 298 1.5E-44 T 11-10-2018 IPR000352 Peptide chain release factor class I/class II GO:0003747|GO:0006415 AFK25_13125 6bbedf874463d64786a103e01406e496 329 Pfam PF03462 PCRF domain 1 179 1.9E-61 T 11-10-2018 IPR005139 Peptide chain release factor GO:0006415 AFK25_13125 6bbedf874463d64786a103e01406e496 329 Gene3D G3DSA:3.30.70.1660 90 318 1.8E-100 T 11-10-2018 AFK25_00125 29d61fa59a566f8f1318b6f66483095a 107 Gene3D G3DSA:3.30.1310.10 2 107 8.0E-40 T 11-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily AFK25_00125 29d61fa59a566f8f1318b6f66483095a 107 PIRSF PIRSF004555 4 107 5.6E-40 T 11-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFK25_00125 29d61fa59a566f8f1318b6f66483095a 107 TIGRFAM TIGR00103 DNA_YbaB_EbfC: DNA-binding protein, YbaB/EbfC family 1 106 1.4E-33 T 11-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFK25_00125 29d61fa59a566f8f1318b6f66483095a 107 Hamap MF_00274 Nucleoid-associated protein YbaB [ybaB]. 6 100 23.735 T 11-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFK25_00125 29d61fa59a566f8f1318b6f66483095a 107 SUPERFAMILY SSF82607 12 106 1.7E-34 T 11-10-2018 IPR036894 Nucleoid-associated protein YbaB-like domain superfamily AFK25_00125 29d61fa59a566f8f1318b6f66483095a 107 Pfam PF02575 YbaB/EbfC DNA-binding family 12 102 2.9E-35 T 11-10-2018 IPR004401 Nucleoid-associated protein YbaB/EbfC family AFK25_11185 cc8a4e78cef2d4b1fafcb14f05865275 172 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 77 2.0E-34 T 11-10-2018 AFK25_11185 cc8a4e78cef2d4b1fafcb14f05865275 172 Pfam PF13710 ACT domain 11 74 3.5E-15 T 11-10-2018 AFK25_11185 cc8a4e78cef2d4b1fafcb14f05865275 172 SUPERFAMILY SSF55021 2 77 6.79E-22 T 11-10-2018 AFK25_11185 cc8a4e78cef2d4b1fafcb14f05865275 172 Gene3D G3DSA:3.30.70.260 1 80 5.6E-33 T 11-10-2018 AFK25_11185 cc8a4e78cef2d4b1fafcb14f05865275 172 Gene3D G3DSA:3.30.70.1150 84 165 2.1E-28 T 11-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal AFK25_11185 cc8a4e78cef2d4b1fafcb14f05865275 172 Pfam PF10369 Small subunit of acetolactate synthase 85 158 2.4E-28 T 11-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AFK25_11185 cc8a4e78cef2d4b1fafcb14f05865275 172 SUPERFAMILY SSF55021 80 160 1.46E-25 T 11-10-2018 AFK25_11185 cc8a4e78cef2d4b1fafcb14f05865275 172 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 2 158 1.0E-65 T 11-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AFK25_03375 5b24b6d35b5646ca3ea97a86ea8bcce8 263 PRINTS PR00474 Glutamate 5-kinase family signature 40 54 4.4E-6 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFK25_03375 5b24b6d35b5646ca3ea97a86ea8bcce8 263 PRINTS PR00474 Glutamate 5-kinase family signature 166 193 4.4E-6 T 11-10-2018 IPR001057 Glutamate/acetylglutamate kinase Reactome: R-HSA-70614 AFK25_03375 5b24b6d35b5646ca3ea97a86ea8bcce8 263 SUPERFAMILY SSF53633 12 256 2.75E-67 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFK25_03375 5b24b6d35b5646ca3ea97a86ea8bcce8 263 Gene3D G3DSA:3.40.1160.10 1 260 5.8E-78 T 11-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AFK25_03375 5b24b6d35b5646ca3ea97a86ea8bcce8 263 PIRSF PIRSF000728 2 259 3.6E-89 T 11-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFK25_03375 5b24b6d35b5646ca3ea97a86ea8bcce8 263 TIGRFAM TIGR00761 argB: acetylglutamate kinase 12 237 3.5E-79 T 11-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFK25_03375 5b24b6d35b5646ca3ea97a86ea8bcce8 263 Pfam PF00696 Amino acid kinase family 12 239 1.9E-43 T 11-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AFK25_03375 5b24b6d35b5646ca3ea97a86ea8bcce8 263 Hamap MF_00082 Acetylglutamate kinase [argB]. 10 250 43.017 T 11-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AFK25_08950 e8f408cc82afe9b1fa19d231857169f3 75 Pfam PF02081 Tryptophan RNA-binding attenuator protein 3 70 2.0E-41 T 11-10-2018 IPR023558 Tryptophan RNA-binding attenuator protein domain AFK25_08950 e8f408cc82afe9b1fa19d231857169f3 75 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 23 39 1.1E-36 T 11-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 AFK25_08950 e8f408cc82afe9b1fa19d231857169f3 75 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 39 55 1.1E-36 T 11-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 AFK25_08950 e8f408cc82afe9b1fa19d231857169f3 75 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 6 23 1.1E-36 T 11-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 AFK25_08950 e8f408cc82afe9b1fa19d231857169f3 75 PRINTS PR00687 Tryptophan RNA-binding attenuator protein signature 55 71 1.1E-36 T 11-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 AFK25_08950 e8f408cc82afe9b1fa19d231857169f3 75 Hamap MF_00798 Transcription attenuation protein MtrB [mtrB]. 1 70 27.319 T 11-10-2018 IPR000824 Transcription attenuation protein MtrB GO:0003723|GO:0006353|GO:0006355 AFK25_08950 e8f408cc82afe9b1fa19d231857169f3 75 Gene3D G3DSA:2.60.40.50 1 73 8.2E-42 T 11-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily AFK25_08950 e8f408cc82afe9b1fa19d231857169f3 75 SUPERFAMILY SSF51219 5 71 7.85E-36 T 11-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily AFK25_00415 1739afdb8524dc0d2e1ac89857f2d8d9 120 SMART SM00905 5 118 6.0E-52 T 11-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AFK25_00415 1739afdb8524dc0d2e1ac89857f2d8d9 120 Gene3D G3DSA:3.30.1130.10 1 120 2.6E-47 T 11-10-2018 AFK25_00415 1739afdb8524dc0d2e1ac89857f2d8d9 120 SUPERFAMILY SSF55620 1 120 2.49E-41 T 11-10-2018 AFK25_00415 1739afdb8524dc0d2e1ac89857f2d8d9 120 TIGRFAM TIGR00525 folB: dihydroneopterin aldolase 3 118 7.5E-42 T 11-10-2018 IPR006156 Dihydroneopterin aldolase GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AFK25_00415 1739afdb8524dc0d2e1ac89857f2d8d9 120 Pfam PF02152 Dihydroneopterin aldolase 5 117 1.1E-36 T 11-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AFK25_00415 1739afdb8524dc0d2e1ac89857f2d8d9 120 TIGRFAM TIGR00526 folB_dom: FolB domain 3 119 1.1E-36 T 11-10-2018 IPR006157 Dihydroneopterin aldolase/epimerase domain GO:0004150|GO:0006760 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AFK25_04395 85cd68b1b173943cbf590bb0681c3b0c 390 Pfam PF00155 Aminotransferase class I and II 34 384 3.7E-67 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFK25_04395 85cd68b1b173943cbf590bb0681c3b0c 390 Gene3D G3DSA:3.90.1150.10 30 384 5.6E-120 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_04395 85cd68b1b173943cbf590bb0681c3b0c 390 SUPERFAMILY SSF53383 6 387 6.19E-108 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_04395 85cd68b1b173943cbf590bb0681c3b0c 390 Gene3D G3DSA:3.40.640.10 45 286 5.6E-120 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_11270 996edd6989118fa4bb2b43fd1219de7b 304 Pfam PF03239 Iron permease FTR1 family 3 203 5.5E-33 T 11-10-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0016020|GO:0033573|GO:0034755 AFK25_09945 d2ae1326ca288cae5e8ead194b38c880 142 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 3 60 3.9E-25 T 11-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 AFK25_09945 d2ae1326ca288cae5e8ead194b38c880 142 SMART SM00529 24 123 3.8E-44 T 11-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 AFK25_09945 d2ae1326ca288cae5e8ead194b38c880 142 Gene3D G3DSA:1.10.10.10 2 73 5.6E-26 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_09945 d2ae1326ca288cae5e8ead194b38c880 142 SUPERFAMILY SSF47979 63 133 3.92E-19 T 11-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 AFK25_09945 d2ae1326ca288cae5e8ead194b38c880 142 SUPERFAMILY SSF46785 3 62 2.12E-17 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_09945 d2ae1326ca288cae5e8ead194b38c880 142 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 124 1.9E-18 T 11-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 AFK25_09945 d2ae1326ca288cae5e8ead194b38c880 142 Gene3D G3DSA:1.10.60.10 74 142 1.0E-32 T 11-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 AFK25_09945 d2ae1326ca288cae5e8ead194b38c880 142 Hamap MF_00732 Transcriptional regulator MntR [mntR]. 1 139 45.942 T 11-10-2018 IPR022897 HTH-type transcription regulator MntR AFK25_00650 e9054a3836e13f946db8cb1dd2ce6a56 87 ProSitePatterns PS00056 Ribosomal protein S17 signature. 58 70 - T 11-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00650 e9054a3836e13f946db8cb1dd2ce6a56 87 SUPERFAMILY SSF50249 7 84 7.71E-33 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_00650 e9054a3836e13f946db8cb1dd2ce6a56 87 Gene3D G3DSA:2.40.50.140 6 86 1.2E-36 T 11-10-2018 AFK25_00650 e9054a3836e13f946db8cb1dd2ce6a56 87 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 7 78 2.0E-33 T 11-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00650 e9054a3836e13f946db8cb1dd2ce6a56 87 Pfam PF00366 Ribosomal protein S17 12 79 1.2E-33 T 11-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00650 e9054a3836e13f946db8cb1dd2ce6a56 87 Hamap MF_01345_B 30S ribosomal protein S17 [rpsQ]. 7 82 25.117 T 11-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00650 e9054a3836e13f946db8cb1dd2ce6a56 87 TIGRFAM TIGR03635 uS17_bact: ribosomal protein uS17 7 78 8.5E-37 T 11-10-2018 IPR019984 30S ribosomal protein S17 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00650 e9054a3836e13f946db8cb1dd2ce6a56 87 PRINTS PR00973 Ribosomal protein S17 family signature 68 75 7.9E-13 T 11-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00650 e9054a3836e13f946db8cb1dd2ce6a56 87 PRINTS PR00973 Ribosomal protein S17 family signature 26 49 7.9E-13 T 11-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00650 e9054a3836e13f946db8cb1dd2ce6a56 87 PRINTS PR00973 Ribosomal protein S17 family signature 58 68 7.9E-13 T 11-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_10975 8f59b3ce1c4faf7d9add7b79b600d14a 189 Hamap MF_00528 Septum formation protein Maf [maf]. 2 187 32.088 T 11-10-2018 IPR003697 Maf-like protein GO:0047429 AFK25_10975 8f59b3ce1c4faf7d9add7b79b600d14a 189 SUPERFAMILY SSF52972 1 182 1.63E-64 T 11-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFK25_10975 8f59b3ce1c4faf7d9add7b79b600d14a 189 Pfam PF02545 Maf-like protein 2 182 1.2E-62 T 11-10-2018 IPR003697 Maf-like protein GO:0047429 AFK25_10975 8f59b3ce1c4faf7d9add7b79b600d14a 189 Gene3D G3DSA:3.90.950.10 1 186 1.2E-76 T 11-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFK25_10975 8f59b3ce1c4faf7d9add7b79b600d14a 189 TIGRFAM TIGR00172 maf: septum formation protein Maf 1 181 2.3E-64 T 11-10-2018 IPR003697 Maf-like protein GO:0047429 AFK25_10975 8f59b3ce1c4faf7d9add7b79b600d14a 189 PIRSF PIRSF006305 1 188 2.0E-61 T 11-10-2018 IPR003697 Maf-like protein GO:0047429 AFK25_11790 33d50bbc954b557d4e01492ae47ddcd5 256 SUPERFAMILY SSF52540 3 253 2.04E-67 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_11790 33d50bbc954b557d4e01492ae47ddcd5 256 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 229 251 1.8E-10 T 11-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AFK25_11790 33d50bbc954b557d4e01492ae47ddcd5 256 SMART SM00382 28 228 7.6E-10 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_11790 33d50bbc954b557d4e01492ae47ddcd5 256 Pfam PF00005 ABC transporter 19 180 1.6E-31 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_11790 33d50bbc954b557d4e01492ae47ddcd5 256 Gene3D G3DSA:3.40.50.300 2 255 4.6E-65 T 11-10-2018 AFK25_11305 f81e9b956735f97355de7217417cf8b4 104 Pfam PF00085 Thioredoxin 3 103 1.6E-31 T 11-10-2018 IPR013766 Thioredoxin domain GO:0045454 AFK25_11305 f81e9b956735f97355de7217417cf8b4 104 SUPERFAMILY SSF52833 3 104 7.38E-39 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_11305 f81e9b956735f97355de7217417cf8b4 104 TIGRFAM TIGR01068 thioredoxin: thioredoxin 7 103 2.4E-39 T 11-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFK25_11305 f81e9b956735f97355de7217417cf8b4 104 PIRSF PIRSF000077 1 104 1.3E-42 T 11-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AFK25_11305 f81e9b956735f97355de7217417cf8b4 104 PRINTS PR00421 Thioredoxin family signature 28 37 1.2E-9 T 11-10-2018 AFK25_11305 f81e9b956735f97355de7217417cf8b4 104 PRINTS PR00421 Thioredoxin family signature 20 28 1.2E-9 T 11-10-2018 AFK25_11305 f81e9b956735f97355de7217417cf8b4 104 PRINTS PR00421 Thioredoxin family signature 68 79 1.2E-9 T 11-10-2018 AFK25_11305 f81e9b956735f97355de7217417cf8b4 104 ProSitePatterns PS00194 Thioredoxin family active site. 21 39 - T 11-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFK25_11305 f81e9b956735f97355de7217417cf8b4 104 Gene3D G3DSA:3.40.30.10 1 104 2.2E-36 T 11-10-2018 AFK25_10060 5621ecac64bf951184b3b67f51849dbd 210 SMART SM00849 12 191 2.0E-45 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_10060 5621ecac64bf951184b3b67f51849dbd 210 SUPERFAMILY SSF56281 1 208 3.93E-55 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_10060 5621ecac64bf951184b3b67f51849dbd 210 Pfam PF00753 Metallo-beta-lactamase superfamily 9 191 1.9E-34 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_10060 5621ecac64bf951184b3b67f51849dbd 210 Gene3D G3DSA:3.60.15.10 1 209 4.0E-65 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_00925 7303fbecd498ed1e3d3d8070eb3e7007 119 Gene3D G3DSA:3.20.20.210 2 111 1.6E-45 T 11-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AFK25_00925 7303fbecd498ed1e3d3d8070eb3e7007 119 SUPERFAMILY SSF51726 5 111 1.36E-31 T 11-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AFK25_00925 7303fbecd498ed1e3d3d8070eb3e7007 119 Pfam PF08267 Cobalamin-independent synthase, N-terminal domain 5 110 3.1E-43 T 11-10-2018 IPR013215 Cobalamin-independent methionine synthase MetE, N-terminal GO:0003871|GO:0008270|GO:0008652 KEGG: 00270+2.1.1.14|KEGG: 00450+2.1.1.14|MetaCyc: PWY-5041|MetaCyc: PWY-6151|MetaCyc: PWY-6936|MetaCyc: PWY-702 AFK25_01535 9783a2c981fb96a59f12f6f96c875ee0 389 Pfam PF00665 Integrase core domain 105 231 8.2E-27 T 11-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFK25_01535 9783a2c981fb96a59f12f6f96c875ee0 389 Gene3D G3DSA:3.30.420.10 102 276 2.8E-10 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFK25_01535 9783a2c981fb96a59f12f6f96c875ee0 389 SUPERFAMILY SSF53098 104 275 5.5E-22 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_11290 fd6b5058c6450333e995db9d13806881 305 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 12 285 2.4E-27 T 11-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AFK25_13225 d0c9e3cd7fbd6a0f4b7a3fa0c5cdb46b 72 ProDom PD009007 STORAGE CARBON REGULATOR RNA-BINDING HOMOLOG CSRA REGULATOR GLOBAL PLASMID RSMA 1 48 2.0E-15 T 11-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 AFK25_13225 d0c9e3cd7fbd6a0f4b7a3fa0c5cdb46b 72 Pfam PF02599 Global regulator protein family 1 53 3.8E-26 T 11-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 AFK25_13225 d0c9e3cd7fbd6a0f4b7a3fa0c5cdb46b 72 Hamap MF_00167 Translational regulator CsrA [csrA]. 1 72 17.231 T 11-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 AFK25_13225 d0c9e3cd7fbd6a0f4b7a3fa0c5cdb46b 72 SUPERFAMILY SSF117130 1 55 1.83E-20 T 11-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 AFK25_13225 d0c9e3cd7fbd6a0f4b7a3fa0c5cdb46b 72 Gene3D G3DSA:3.30.70.1680 1 63 2.8E-29 T 11-10-2018 IPR036107 Carbon storage regulator superfamily GO:0003723|GO:0006109|GO:0006402 AFK25_13225 d0c9e3cd7fbd6a0f4b7a3fa0c5cdb46b 72 TIGRFAM TIGR00202 csrA: carbon storage regulator 1 68 3.6E-31 T 11-10-2018 IPR003751 Translational regulator CsrA GO:0003723|GO:0006109|GO:0006402 AFK25_00610 9f60ab69a63b392df3e07d938498f416 207 Pfam PF00573 Ribosomal protein L4/L1 family 17 204 5.3E-78 T 11-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 AFK25_00610 9f60ab69a63b392df3e07d938498f416 207 Hamap MF_01328_B 50S ribosomal protein L4 [rplD]. 9 207 39.468 T 11-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00610 9f60ab69a63b392df3e07d938498f416 207 SUPERFAMILY SSF52166 1 206 4.32E-90 T 11-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 AFK25_00610 9f60ab69a63b392df3e07d938498f416 207 Gene3D G3DSA:3.40.1370.10 3 207 1.5E-89 T 11-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 AFK25_00610 9f60ab69a63b392df3e07d938498f416 207 TIGRFAM TIGR03953 rplD_bact: 50S ribosomal protein uL4 17 204 1.3E-87 T 11-10-2018 IPR013005 50S ribosomal protein uL4 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_12690 0f89e9834b67603d3884dae2f4610147 503 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 312 331 2.0E-27 T 11-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AFK25_12690 0f89e9834b67603d3884dae2f4610147 503 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 12 33 2.0E-27 T 11-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AFK25_12690 0f89e9834b67603d3884dae2f4610147 503 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 41 60 2.0E-27 T 11-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AFK25_12690 0f89e9834b67603d3884dae2f4610147 503 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 85 111 2.0E-27 T 11-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AFK25_12690 0f89e9834b67603d3884dae2f4610147 503 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 389 409 2.0E-27 T 11-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AFK25_12690 0f89e9834b67603d3884dae2f4610147 503 Pfam PF00209 Sodium:neurotransmitter symporter family 126 479 1.6E-72 T 11-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AFK25_12690 0f89e9834b67603d3884dae2f4610147 503 Pfam PF00209 Sodium:neurotransmitter symporter family 4 120 1.2E-38 T 11-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AFK25_12690 0f89e9834b67603d3884dae2f4610147 503 SUPERFAMILY SSF161070 4 488 7.06E-145 T 11-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 AFK25_07420 9dd130eda72061d0c2b310403b841b2b 364 Pfam PF07993 Male sterility protein 8 241 1.5E-46 T 11-10-2018 IPR013120 Male sterility, NAD-binding Reactome: R-HSA-8848584 AFK25_07420 9dd130eda72061d0c2b310403b841b2b 364 SUPERFAMILY SSF51735 1 355 7.31E-35 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_07420 9dd130eda72061d0c2b310403b841b2b 364 Gene3D G3DSA:3.40.50.720 1 357 8.1E-63 T 11-10-2018 AFK25_10435 00a4ee2453428b610173327969ced463 44 Pfam PF14141 YqzM-like protein 2 43 1.2E-23 T 11-10-2018 IPR025416 YqzM-like protein AFK25_12705 868da122de25c448c38398b67090c5dd 462 Gene3D G3DSA:3.60.21.10 1 279 4.8E-56 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like AFK25_12705 868da122de25c448c38398b67090c5dd 462 SUPERFAMILY SSF55816 280 460 6.02E-30 T 11-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFK25_12705 868da122de25c448c38398b67090c5dd 462 PRINTS PR01607 Apyrase family signature 187 210 9.3E-17 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFK25_12705 868da122de25c448c38398b67090c5dd 462 PRINTS PR01607 Apyrase family signature 215 235 9.3E-17 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFK25_12705 868da122de25c448c38398b67090c5dd 462 PRINTS PR01607 Apyrase family signature 3 21 9.3E-17 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFK25_12705 868da122de25c448c38398b67090c5dd 462 PRINTS PR01607 Apyrase family signature 168 185 9.3E-17 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFK25_12705 868da122de25c448c38398b67090c5dd 462 PRINTS PR01607 Apyrase family signature 412 431 9.3E-17 T 11-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFK25_12705 868da122de25c448c38398b67090c5dd 462 Pfam PF00149 Calcineurin-like phosphoesterase 6 204 5.1E-10 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFK25_12705 868da122de25c448c38398b67090c5dd 462 SUPERFAMILY SSF56300 4 274 8.5E-64 T 11-10-2018 AFK25_12705 868da122de25c448c38398b67090c5dd 462 Gene3D G3DSA:3.90.780.10 286 460 2.0E-15 T 11-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFK25_12705 868da122de25c448c38398b67090c5dd 462 PIRSF PIRSF036361 1 462 3.6E-173 T 11-10-2018 IPR011240 Phosphoesterase-related protein YunD AFK25_12705 868da122de25c448c38398b67090c5dd 462 Pfam PF02872 5'-nucleotidase, C-terminal domain 290 425 9.4E-15 T 11-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AFK25_12245 43829dc998998f095cadb6e3f10c911f 99 Pfam PF10087 Uncharacterized protein conserved in bacteria (DUF2325) 3 91 4.5E-19 T 11-10-2018 IPR016772 Uncharacterised conserved protein UCP020408 AFK25_12245 43829dc998998f095cadb6e3f10c911f 99 PIRSF PIRSF020408 2 99 2.5E-37 T 11-10-2018 IPR016772 Uncharacterised conserved protein UCP020408 AFK25_01055 78ac9fa7723e1cc00f522ac04f1644ae 376 Gene3D G3DSA:3.30.300.210 231 375 4.9E-12 T 11-10-2018 IPR038501 Spore germination GerAC superfamily AFK25_01055 78ac9fa7723e1cc00f522ac04f1644ae 376 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 215 371 5.7E-18 T 11-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 AFK25_01055 78ac9fa7723e1cc00f522ac04f1644ae 376 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 2 373 3.2E-69 T 11-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 AFK25_11190 fadbd2a40800c9fb023b035c449699d8 572 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 435 454 - T 11-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 AFK25_11190 fadbd2a40800c9fb023b035c449699d8 572 SUPERFAMILY SSF52518 376 569 1.84E-72 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold AFK25_11190 fadbd2a40800c9fb023b035c449699d8 572 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 18 570 2.6E-273 T 11-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AFK25_11190 fadbd2a40800c9fb023b035c449699d8 572 SUPERFAMILY SSF52467 198 367 7.89E-65 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFK25_11190 fadbd2a40800c9fb023b035c449699d8 572 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 21 183 1.2E-53 T 11-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AFK25_11190 fadbd2a40800c9fb023b035c449699d8 572 Gene3D G3DSA:3.40.50.970 368 571 5.2E-74 T 11-10-2018 AFK25_11190 fadbd2a40800c9fb023b035c449699d8 572 Gene3D G3DSA:3.40.50.970 9 194 1.1E-69 T 11-10-2018 AFK25_11190 fadbd2a40800c9fb023b035c449699d8 572 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 206 341 4.6E-48 T 11-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AFK25_11190 fadbd2a40800c9fb023b035c449699d8 572 SUPERFAMILY SSF52518 13 192 3.93E-59 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold AFK25_11190 fadbd2a40800c9fb023b035c449699d8 572 Gene3D G3DSA:3.40.50.1220 200 365 1.3E-64 T 11-10-2018 AFK25_11190 fadbd2a40800c9fb023b035c449699d8 572 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 398 545 1.6E-53 T 11-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFK25_09560 a57e7ab2cba415fcad180126c8d1596c 231 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 27 220 5.0E-19 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_09560 a57e7ab2cba415fcad180126c8d1596c 231 TIGRFAM TIGR02141 modB_ABC: molybdate ABC transporter, permease protein 11 219 8.7E-69 T 11-10-2018 IPR011867 Molybdate ABC transporter, permease protein GO:0015098|GO:0015689|GO:0016021 AFK25_09560 a57e7ab2cba415fcad180126c8d1596c 231 SUPERFAMILY SSF161098 7 217 4.19E-49 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_09560 a57e7ab2cba415fcad180126c8d1596c 231 Gene3D G3DSA:1.10.3720.10 2 225 1.1E-58 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_09740 928522f5410f6776598eaf55f8e059d2 659 ProSitePatterns PS00544 Methylmalonyl-CoA mutase signature. 354 379 - T 11-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFK25_09740 928522f5410f6776598eaf55f8e059d2 659 SUPERFAMILY SSF52242 493 653 1.24E-33 T 11-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 AFK25_09740 928522f5410f6776598eaf55f8e059d2 659 Gene3D G3DSA:3.40.50.280 517 655 5.6E-26 T 11-10-2018 AFK25_09740 928522f5410f6776598eaf55f8e059d2 659 Pfam PF01642 Methylmalonyl-CoA mutase 33 548 1.4E-145 T 11-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFK25_09740 928522f5410f6776598eaf55f8e059d2 659 Gene3D G3DSA:3.20.20.240 7 500 4.4E-161 T 11-10-2018 AFK25_09740 928522f5410f6776598eaf55f8e059d2 659 SUPERFAMILY SSF51703 5 553 1.73E-147 T 11-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AFK25_04860 b4b78a9006fd9e8fdf688a16a64131e5 368 Gene3D G3DSA:3.40.50.970 3 368 8.2E-126 T 11-10-2018 AFK25_04860 b4b78a9006fd9e8fdf688a16a64131e5 368 SUPERFAMILY SSF52518 15 363 2.03E-103 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold AFK25_04860 b4b78a9006fd9e8fdf688a16a64131e5 368 Pfam PF00676 Dehydrogenase E1 component 50 340 5.6E-105 T 11-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 AFK25_04860 b4b78a9006fd9e8fdf688a16a64131e5 368 TIGRFAM TIGR03181 PDH_E1_alph_x: pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit 22 361 3.5E-144 T 11-10-2018 IPR017596 Pyruvate dehydrogenase E1 component subunit alpha/BCKADH E1-alpha KEGG: 00010+1.2.4.1|KEGG: 00020+1.2.4.1|KEGG: 00620+1.2.4.1 AFK25_00180 210f676200fd6e364755e8830b62a05c 209 Pfam PF02223 Thymidylate kinase 8 198 2.6E-53 T 11-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 AFK25_00180 210f676200fd6e364755e8830b62a05c 209 SUPERFAMILY SSF52540 1 207 2.86E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_00180 210f676200fd6e364755e8830b62a05c 209 Hamap MF_00165 Thymidylate kinase [tmk]. 4 207 30.844 T 11-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AFK25_00180 210f676200fd6e364755e8830b62a05c 209 Gene3D G3DSA:3.40.50.300 2 209 2.1E-65 T 11-10-2018 AFK25_00180 210f676200fd6e364755e8830b62a05c 209 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 3 198 2.1E-59 T 11-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AFK25_00180 210f676200fd6e364755e8830b62a05c 209 ProSitePatterns PS01331 Thymidylate kinase signature. 93 105 - T 11-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AFK25_05915 b418d340968b6c5444abdb3e8b7e228d 89 SMART SM01387 8 88 3.3E-53 T 11-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_05915 b418d340968b6c5444abdb3e8b7e228d 89 TIGRFAM TIGR00952 S15_bact: ribosomal protein uS15 4 89 1.2E-42 T 11-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_05915 b418d340968b6c5444abdb3e8b7e228d 89 Gene3D G3DSA:1.10.287.10 2 89 1.6E-37 T 11-10-2018 AFK25_05915 b418d340968b6c5444abdb3e8b7e228d 89 ProSitePatterns PS00362 Ribosomal protein S15 signature. 39 69 - T 11-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_05915 b418d340968b6c5444abdb3e8b7e228d 89 Pfam PF00312 Ribosomal protein S15 8 88 2.1E-38 T 11-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_05915 b418d340968b6c5444abdb3e8b7e228d 89 ProDom PD157043 RIBOSOMAL S15 RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 30S CHLOROPLAST S15 MITOCHONDRIAL TYPE 10 88 1.0E-34 T 11-10-2018 AFK25_05915 b418d340968b6c5444abdb3e8b7e228d 89 Hamap MF_01343_B 30S ribosomal protein S15 [rpsO]. 3 89 23.397 T 11-10-2018 IPR005290 Ribosomal protein S15, bacterial-type GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_05915 b418d340968b6c5444abdb3e8b7e228d 89 SUPERFAMILY SSF47060 3 89 1.91E-37 T 11-10-2018 IPR009068 S15/NS1, RNA-binding AFK25_05415 a739f32fd0353d04055e88ac477da867 804 Hamap MF_00983 Probable primosomal protein N' [priA]. 9 803 25.632 T 11-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 AFK25_05415 a739f32fd0353d04055e88ac477da867 804 Pfam PF04851 Type III restriction enzyme, res subunit 266 429 1.8E-16 T 11-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFK25_05415 a739f32fd0353d04055e88ac477da867 804 SMART SM00490 565 662 8.2E-10 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_05415 a739f32fd0353d04055e88ac477da867 804 Pfam PF00271 Helicase conserved C-terminal domain 561 661 5.2E-8 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_05415 a739f32fd0353d04055e88ac477da867 804 Gene3D G3DSA:3.40.50.300 254 449 8.9E-77 T 11-10-2018 AFK25_05415 a739f32fd0353d04055e88ac477da867 804 SMART SM00487 263 462 1.0E-23 T 11-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AFK25_05415 a739f32fd0353d04055e88ac477da867 804 TIGRFAM TIGR00595 priA: primosomal protein N' 291 801 2.0E-220 T 11-10-2018 IPR005259 Primosomal protein N' GO:0003677|GO:0004003|GO:0006260|GO:0032508 AFK25_05415 a739f32fd0353d04055e88ac477da867 804 SUPERFAMILY SSF52540 533 702 3.19E-35 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_05415 a739f32fd0353d04055e88ac477da867 804 SUPERFAMILY SSF52540 238 447 2.62E-42 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_05415 a739f32fd0353d04055e88ac477da867 804 Gene3D G3DSA:1.10.8.630 2 116 4.1E-27 T 11-10-2018 AFK25_05795 a57b33bec538bfc541573bc0ca0f661f 166 SUPERFAMILY SSF64438 7 164 2.11E-50 T 11-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic AFK25_05795 a57b33bec538bfc541573bc0ca0f661f 166 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 4 162 28.875 T 11-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 AFK25_05795 a57b33bec538bfc541573bc0ca0f661f 166 Pfam PF03975 CheD chemotactic sensory transduction 51 158 9.2E-39 T 11-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 AFK25_05795 a57b33bec538bfc541573bc0ca0f661f 166 Gene3D G3DSA:3.30.1330.200 5 166 2.4E-51 T 11-10-2018 IPR038592 CheD-like superfamily AFK25_00110 82f06ed091036605b7560bde11fd1d42 212 Gene3D G3DSA:3.40.50.300 5 208 4.1E-49 T 11-10-2018 AFK25_00110 82f06ed091036605b7560bde11fd1d42 212 SUPERFAMILY SSF52540 1 206 1.39E-50 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_00110 82f06ed091036605b7560bde11fd1d42 212 Pfam PF01712 Deoxynucleoside kinase 7 206 7.4E-49 T 11-10-2018 IPR031314 Deoxynucleoside kinase domain AFK25_00110 82f06ed091036605b7560bde11fd1d42 212 PIRSF PIRSF000705 1 211 1.1E-56 T 11-10-2018 IPR002624 Deoxynucleoside kinase GO:0005524|GO:0006139|GO:0019206 AFK25_03355 f7b0b770cd32a22a1ce77ec17cf5c553 235 Pfam PF14256 YwiC-like protein 3 126 2.7E-40 T 11-10-2018 IPR025576 YwiC-like protein AFK25_05685 705b51386968b7be5875edb063ebacb1 147 TIGRFAM TIGR02473 flagell_FliJ: flagellar export protein FliJ 4 141 3.1E-27 T 11-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 AFK25_05685 705b51386968b7be5875edb063ebacb1 147 Pfam PF02050 Flagellar FliJ protein 19 141 3.0E-21 T 11-10-2018 IPR012823 Flagellar export FliJ GO:0009288|GO:0071973 AFK25_03860 159ecfdc0ebf732b3c4e4de597ddfe2b 436 Pfam PF05133 Phage portal protein, SPP1 Gp6-like 28 427 5.7E-66 T 11-10-2018 IPR021145 Portal protein AFK25_02745 eb29f0eab41bdc9e011bdd1a09488fa6 244 Gene3D G3DSA:3.40.50.300 1 244 2.0E-80 T 11-10-2018 AFK25_02745 eb29f0eab41bdc9e011bdd1a09488fa6 244 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_02745 eb29f0eab41bdc9e011bdd1a09488fa6 244 PIRSF PIRSF039085 1 244 1.3E-118 T 11-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 AFK25_02745 eb29f0eab41bdc9e011bdd1a09488fa6 244 Pfam PF00005 ABC transporter 17 169 2.0E-37 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_02745 eb29f0eab41bdc9e011bdd1a09488fa6 244 SUPERFAMILY SSF52540 1 239 5.02E-82 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_02745 eb29f0eab41bdc9e011bdd1a09488fa6 244 SMART SM00382 26 223 2.7E-17 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_01365 060371f0e2f330b8247fb9be48d0c81d 231 Pfam PF01884 PcrB family 3 226 2.4E-79 T 11-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 AFK25_01365 060371f0e2f330b8247fb9be48d0c81d 231 SUPERFAMILY SSF51395 4 223 1.83E-55 T 11-10-2018 AFK25_01365 060371f0e2f330b8247fb9be48d0c81d 231 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 8 224 6.4E-74 T 11-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 AFK25_01365 060371f0e2f330b8247fb9be48d0c81d 231 Gene3D G3DSA:3.20.20.390 1 230 1.6E-95 T 11-10-2018 IPR038597 GGGP/HepGP synthase superfamily AFK25_01365 060371f0e2f330b8247fb9be48d0c81d 231 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 3 226 27.563 T 11-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 AFK25_13795 0079f7cc3b9feb66f90ac6fec5c31305 169 Pfam PF00499 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 19 159 1.9E-36 T 11-10-2018 IPR001457 NADH:ubiquinone/plastoquinone oxidoreductase, chain 6 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13795 0079f7cc3b9feb66f90ac6fec5c31305 169 Gene3D G3DSA:1.20.120.1200 5 161 8.5E-40 T 11-10-2018 AFK25_00625 a06c292e28e4af67b74a9df9cbcb0ae7 92 SUPERFAMILY SSF54570 3 84 4.97E-36 T 11-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00625 a06c292e28e4af67b74a9df9cbcb0ae7 92 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 1 89 25.921 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00625 a06c292e28e4af67b74a9df9cbcb0ae7 92 Gene3D G3DSA:3.30.860.10 1 92 3.3E-42 T 11-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00625 a06c292e28e4af67b74a9df9cbcb0ae7 92 ProSitePatterns PS00323 Ribosomal protein S19 signature. 53 77 - T 11-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00625 a06c292e28e4af67b74a9df9cbcb0ae7 92 Pfam PF00203 Ribosomal protein S19 3 83 2.3E-37 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00625 a06c292e28e4af67b74a9df9cbcb0ae7 92 PRINTS PR00975 Ribosomal protein S19 family signature 53 65 6.3E-25 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00625 a06c292e28e4af67b74a9df9cbcb0ae7 92 PRINTS PR00975 Ribosomal protein S19 family signature 65 80 6.3E-25 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00625 a06c292e28e4af67b74a9df9cbcb0ae7 92 PRINTS PR00975 Ribosomal protein S19 family signature 33 52 6.3E-25 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00625 a06c292e28e4af67b74a9df9cbcb0ae7 92 PIRSF PIRSF002144 1 92 1.5E-33 T 11-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00625 a06c292e28e4af67b74a9df9cbcb0ae7 92 TIGRFAM TIGR01050 rpsS_bact: ribosomal protein uS19 1 92 2.7E-48 T 11-10-2018 IPR005732 Ribosomal protein S19, bacterial-type GO:0003735|GO:0006412|GO:0015935 AFK25_06895 2524333fe11fa22bb2bc25ebdd908994 234 Pfam PF02683 Cytochrome C biogenesis protein transmembrane region 8 213 8.2E-63 T 11-10-2018 IPR003834 Cytochrome C biogenesis protein, transmembrane domain GO:0016020|GO:0017004|GO:0055114 AFK25_12050 6c0720ab41a3eefecbaacf42a2fc002e 87 Pfam PF10732 Protein of unknown function (DUF2524) 1 84 2.5E-37 T 11-10-2018 IPR019668 Uncharacterised protein family YtzC AFK25_02470 86a2baa57389b0a7ebe9ff3940bb0991 102 Gene3D G3DSA:3.10.450.40 5 101 3.3E-6 T 11-10-2018 AFK25_02470 86a2baa57389b0a7ebe9ff3940bb0991 102 SUPERFAMILY SSF160719 16 98 3.4E-13 T 11-10-2018 AFK25_05485 d74c0d3144d4ce4dcf76a38fafd2a4ce 220 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 148 220 0.005 T 11-10-2018 AFK25_05485 d74c0d3144d4ce4dcf76a38fafd2a4ce 220 SUPERFAMILY SSF143548 19 137 2.62E-31 T 11-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 AFK25_05485 d74c0d3144d4ce4dcf76a38fafd2a4ce 220 TIGRFAM TIGR00719 sda_beta: L-serine dehydratase, iron-sulfur-dependent, beta subunit 2 205 8.3E-94 T 11-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 AFK25_05485 d74c0d3144d4ce4dcf76a38fafd2a4ce 220 Pfam PF03315 Serine dehydratase beta chain 5 72 8.5E-11 T 11-10-2018 IPR005131 Serine dehydratase beta chain GO:0003941|GO:0006094|GO:0051539 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 AFK25_05485 d74c0d3144d4ce4dcf76a38fafd2a4ce 220 Gene3D G3DSA:3.30.1330.90 13 135 1.7E-20 T 11-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 AFK25_05485 d74c0d3144d4ce4dcf76a38fafd2a4ce 220 SUPERFAMILY SSF55021 137 217 7.4E-18 T 11-10-2018 AFK25_05485 d74c0d3144d4ce4dcf76a38fafd2a4ce 220 PIRSF PIRSF036692 1 220 1.2E-102 T 11-10-2018 IPR004643 Iron-sulphur-dependent L-serine dehydratase beta subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 AFK25_05485 d74c0d3144d4ce4dcf76a38fafd2a4ce 220 Gene3D G3DSA:3.30.70.260 139 217 1.5E-15 T 11-10-2018 AFK25_05485 d74c0d3144d4ce4dcf76a38fafd2a4ce 220 Pfam PF01842 ACT domain 150 210 9.0E-12 T 11-10-2018 IPR002912 ACT domain AFK25_07580 284b6ec4ab3d4488486de4bfa29b9b70 292 SUPERFAMILY SSF161111 9 204 7.06E-53 T 11-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFK25_07580 284b6ec4ab3d4488486de4bfa29b9b70 292 Pfam PF01545 Cation efflux family 11 202 8.6E-47 T 11-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFK25_07580 284b6ec4ab3d4488486de4bfa29b9b70 292 SUPERFAMILY SSF160240 206 284 1.23E-19 T 11-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AFK25_07580 284b6ec4ab3d4488486de4bfa29b9b70 292 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 10 284 4.1E-68 T 11-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFK25_07580 284b6ec4ab3d4488486de4bfa29b9b70 292 Gene3D G3DSA:1.20.1510.10 9 203 4.4E-52 T 11-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFK25_07580 284b6ec4ab3d4488486de4bfa29b9b70 292 Gene3D G3DSA:3.30.70.1350 204 284 2.2E-15 T 11-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AFK25_07580 284b6ec4ab3d4488486de4bfa29b9b70 292 Pfam PF16916 Dimerisation domain of Zinc Transporter 207 283 2.3E-17 T 11-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain AFK25_03660 6ae6d2321cffb7f0d95103efe77fd392 338 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 4 332 3.1E-156 T 11-10-2018 IPR010894 Stage V sporulation AD AFK25_03660 6ae6d2321cffb7f0d95103efe77fd392 338 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 5 332 8.0E-154 T 11-10-2018 IPR010894 Stage V sporulation AD AFK25_03660 6ae6d2321cffb7f0d95103efe77fd392 338 SUPERFAMILY SSF53901 54 308 1.67E-18 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_03660 6ae6d2321cffb7f0d95103efe77fd392 338 PIRSF PIRSF011570 1 335 1.9E-158 T 11-10-2018 IPR010894 Stage V sporulation AD AFK25_03660 6ae6d2321cffb7f0d95103efe77fd392 338 Gene3D G3DSA:3.40.47.40 1 338 5.8E-147 T 11-10-2018 IPR038369 Stage V sporulation AD superfamily AFK25_14410 f3478c7eef05c332c0d0de080ab65456 504 SUPERFAMILY SSF51971 26 378 1.88E-37 T 11-10-2018 AFK25_14410 f3478c7eef05c332c0d0de080ab65456 504 Pfam PF00355 Rieske [2Fe-2S] domain 417 500 9.4E-15 T 11-10-2018 IPR017941 Rieske [2Fe-2S] iron-sulphur domain GO:0016491|GO:0051537|GO:0055114 AFK25_14410 f3478c7eef05c332c0d0de080ab65456 504 Gene3D G3DSA:2.102.10.10 400 504 2.3E-26 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFK25_14410 f3478c7eef05c332c0d0de080ab65456 504 PRINTS PR00162 Rieske 2Fe-2S subunit signature 452 463 1.9E-7 T 11-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 AFK25_14410 f3478c7eef05c332c0d0de080ab65456 504 PRINTS PR00162 Rieske 2Fe-2S subunit signature 473 485 1.9E-7 T 11-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 AFK25_14410 f3478c7eef05c332c0d0de080ab65456 504 PRINTS PR00162 Rieske 2Fe-2S subunit signature 485 497 1.9E-7 T 11-10-2018 IPR005805 Rieske iron-sulphur protein, C-terminal GO:0016020|GO:0055114 AFK25_14410 f3478c7eef05c332c0d0de080ab65456 504 Gene3D G3DSA:3.30.9.10 123 332 5.1E-51 T 11-10-2018 AFK25_14410 f3478c7eef05c332c0d0de080ab65456 504 SUPERFAMILY SSF50022 411 500 2.88E-26 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFK25_14410 f3478c7eef05c332c0d0de080ab65456 504 Gene3D G3DSA:3.50.50.60 30 373 5.1E-51 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_14410 f3478c7eef05c332c0d0de080ab65456 504 Pfam PF01266 FAD dependent oxidoreductase 30 373 3.2E-48 T 11-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFK25_09380 379fb9c4e4bb82c99dfd8ca9d933dcd5 106 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 4 90 1.2E-10 T 11-10-2018 IPR005562 SpoVA AFK25_12135 17c19f2aecd7d4cfc84a88e78ddd6c86 248 Pfam PF02361 Cobalt transport protein 15 219 3.0E-30 T 11-10-2018 IPR003339 ABC/ECF transporter, transmembrane component AFK25_05690 acf321022495fa99fae567283fa73001 200 Pfam PF03448 MgtE intracellular N domain 141 195 2.4E-8 T 11-10-2018 IPR006668 Magnesium transporter, MgtE intracellular domain AFK25_05690 acf321022495fa99fae567283fa73001 200 SUPERFAMILY SSF158791 138 194 3.27E-9 T 11-10-2018 AFK25_05690 acf321022495fa99fae567283fa73001 200 Gene3D G3DSA:1.25.60.10 66 195 7.0E-6 T 11-10-2018 IPR038076 MgtE, N-terminal domain superfamily AFK25_11390 daf834023f0a588b9349199c7c94a32c 69 Pfam PF14098 Small, acid-soluble spore protein I 3 66 3.8E-28 T 11-10-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 AFK25_11390 daf834023f0a588b9349199c7c94a32c 69 TIGRFAM TIGR03092 SASP_sspI: small, acid-soluble spore protein I 4 68 4.3E-33 T 11-10-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 AFK25_11390 daf834023f0a588b9349199c7c94a32c 69 Hamap MF_00669 Small, acid-soluble spore protein I [sspI]. 1 68 20.203 T 11-10-2018 IPR017525 Small, acid-soluble spore protein I GO:0030436 AFK25_10260 7c4375d28cf07e6900192f3578f172c3 372 Gene3D G3DSA:3.40.1390.30 2 125 8.6E-41 T 11-10-2018 AFK25_10260 7c4375d28cf07e6900192f3578f172c3 372 PIRSF PIRSF037489 2 372 3.1E-165 T 11-10-2018 IPR017221 GTP cyclohydrolase 1 type 2//Nif3, bacteria AFK25_10260 7c4375d28cf07e6900192f3578f172c3 372 SUPERFAMILY SSF102705 6 371 1.06E-138 T 11-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily AFK25_10260 7c4375d28cf07e6900192f3578f172c3 372 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 5 367 5.2E-96 T 11-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 AFK25_10260 7c4375d28cf07e6900192f3578f172c3 372 Gene3D G3DSA:3.30.70.120 132 241 3.4E-49 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AFK25_10260 7c4375d28cf07e6900192f3578f172c3 372 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 8 350 2.1E-85 T 11-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 AFK25_03140 ee23c3791d73f384d1e9bb65eca3524c 474 Pfam PF01593 Flavin containing amine oxidoreductase 10 274 2.2E-23 T 11-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AFK25_03140 ee23c3791d73f384d1e9bb65eca3524c 474 SUPERFAMILY SSF51905 1 469 3.17E-63 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_03140 ee23c3791d73f384d1e9bb65eca3524c 474 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 4 470 8.0E-107 T 11-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 AFK25_03140 ee23c3791d73f384d1e9bb65eca3524c 474 Gene3D G3DSA:3.50.50.60 198 288 4.6E-11 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_03140 ee23c3791d73f384d1e9bb65eca3524c 474 Gene3D G3DSA:3.50.50.60 1 98 3.2E-16 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_03140 ee23c3791d73f384d1e9bb65eca3524c 474 PRINTS PR00419 Adrenodoxin reductase family signature 25 38 2.8E-6 T 11-10-2018 AFK25_03140 ee23c3791d73f384d1e9bb65eca3524c 474 PRINTS PR00419 Adrenodoxin reductase family signature 2 24 2.8E-6 T 11-10-2018 AFK25_08620 bb42e96fcf07cf5b4831a35c21ed272c 286 SUPERFAMILY SSF52540 3 230 1.38E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_08620 bb42e96fcf07cf5b4831a35c21ed272c 286 SMART SM00382 28 217 5.0E-15 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_08620 bb42e96fcf07cf5b4831a35c21ed272c 286 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_08620 bb42e96fcf07cf5b4831a35c21ed272c 286 Gene3D G3DSA:3.40.50.300 2 258 2.1E-66 T 11-10-2018 AFK25_08620 bb42e96fcf07cf5b4831a35c21ed272c 286 Pfam PF00005 ABC transporter 20 167 2.5E-31 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_08965 188c199ad7221a6e8f4a8fa551c72048 492 TIGRFAM TIGR02836 spore_IV_A: stage IV sporulation protein A 1 492 5.3E-267 T 11-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 AFK25_08965 188c199ad7221a6e8f4a8fa551c72048 492 SUPERFAMILY SSF52540 19 238 1.75E-14 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_08965 188c199ad7221a6e8f4a8fa551c72048 492 Gene3D G3DSA:3.40.50.300 11 235 1.2E-9 T 11-10-2018 AFK25_08965 188c199ad7221a6e8f4a8fa551c72048 492 Pfam PF09547 Stage IV sporulation protein A (spore_IV_A) 2 492 5.2E-229 T 11-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 AFK25_08965 188c199ad7221a6e8f4a8fa551c72048 492 PIRSF PIRSF007466 1 492 1.1E-272 T 11-10-2018 IPR014201 Sporulation stage IV, protein A GO:0005524|GO:0016887|GO:0043934 KEGG: 00230+3.6.1.3 AFK25_09805 c0dafd82235d273ea8e8a1787dc98bcd 576 Gene3D G3DSA:3.40.50.300 258 567 6.8E-55 T 11-10-2018 AFK25_09805 c0dafd82235d273ea8e8a1787dc98bcd 576 Gene3D G3DSA:3.40.50.300 1 257 2.5E-53 T 11-10-2018 AFK25_09805 c0dafd82235d273ea8e8a1787dc98bcd 576 SUPERFAMILY SSF52540 1 220 5.16E-66 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_09805 c0dafd82235d273ea8e8a1787dc98bcd 576 Pfam PF02463 RecF/RecN/SMC N terminal domain 1 521 1.5E-16 T 11-10-2018 IPR003395 RecF/RecN/SMC, N-terminal AFK25_09805 c0dafd82235d273ea8e8a1787dc98bcd 576 PIRSF PIRSF003128 1 571 1.7E-192 T 11-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 AFK25_09805 c0dafd82235d273ea8e8a1787dc98bcd 576 TIGRFAM TIGR00634 recN: DNA repair protein RecN 1 566 5.7E-198 T 11-10-2018 IPR004604 DNA recombination/repair protein RecN GO:0005524|GO:0006281|GO:0006310 AFK25_09805 c0dafd82235d273ea8e8a1787dc98bcd 576 SUPERFAMILY SSF52540 4 524 3.22E-31 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_05790 7c849878e1fcb65c710147b57ac27a63 211 Pfam PF04509 CheC-like family 111 147 1.3E-11 T 11-10-2018 IPR007597 CheC-like protein GO:0016787 AFK25_05790 7c849878e1fcb65c710147b57ac27a63 211 Pfam PF04509 CheC-like family 11 45 4.4E-13 T 11-10-2018 IPR007597 CheC-like protein GO:0016787 AFK25_05790 7c849878e1fcb65c710147b57ac27a63 211 SUPERFAMILY SSF103039 5 206 4.84E-52 T 11-10-2018 IPR028976 CheC-like superfamily AFK25_05790 7c849878e1fcb65c710147b57ac27a63 211 Gene3D G3DSA:3.40.1550.10 6 209 6.1E-62 T 11-10-2018 IPR028976 CheC-like superfamily AFK25_13115 d4012e57d0cf21478a76bad1f6f694a1 86 Gene3D G3DSA:3.30.2310.20 5 86 5.9E-21 T 11-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AFK25_13115 d4012e57d0cf21478a76bad1f6f694a1 86 SUPERFAMILY SSF143011 4 85 9.55E-21 T 11-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AFK25_13115 d4012e57d0cf21478a76bad1f6f694a1 86 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 12 85 6.2E-7 T 11-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family AFK25_10980 30862f0884cbf2fa3c734068a8741f55 257 SUPERFAMILY SSF110997 111 177 3.66E-5 T 11-10-2018 IPR036680 Sporulation-like domain superfamily GO:0042834 AFK25_03460 8e938353742b88c83ee4328d38783f2d 550 PIRSF PIRSF002741 1 550 5.4E-113 T 11-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 AFK25_03460 8e938353742b88c83ee4328d38783f2d 550 Gene3D G3DSA:3.10.105.10 300 522 3.5E-191 T 11-10-2018 AFK25_03460 8e938353742b88c83ee4328d38783f2d 550 SUPERFAMILY SSF53850 41 547 1.99E-130 T 11-10-2018 AFK25_03460 8e938353742b88c83ee4328d38783f2d 550 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 89 469 9.2E-79 T 11-10-2018 IPR000914 Solute-binding protein family 5 domain AFK25_03460 8e938353742b88c83ee4328d38783f2d 550 Gene3D G3DSA:3.90.76.10 79 200 3.5E-191 T 11-10-2018 AFK25_03460 8e938353742b88c83ee4328d38783f2d 550 Gene3D G3DSA:3.40.190.10 60 539 3.5E-191 T 11-10-2018 AFK25_04115 678b56973d57cb4a06773c1ba05a2f8d 174 SUPERFAMILY SSF53098 103 154 1.14E-12 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_04115 678b56973d57cb4a06773c1ba05a2f8d 174 Pfam PF00665 Integrase core domain 110 151 3.7E-9 T 11-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFK25_04115 678b56973d57cb4a06773c1ba05a2f8d 174 Pfam PF13276 HTH-like domain 30 86 1.9E-17 T 11-10-2018 IPR025948 HTH-like domain AFK25_14440 40c625cb32fc5f238a3ba0768b1530cd 264 SUPERFAMILY SSF161098 8 252 4.21E-49 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_14440 40c625cb32fc5f238a3ba0768b1530cd 264 Gene3D G3DSA:1.10.3720.10 6 263 1.4E-42 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_14440 40c625cb32fc5f238a3ba0768b1530cd 264 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 78 254 9.5E-17 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_07550 526f155bab318e1c28feb47a9b9c8457 298 Pfam PF05067 Manganese containing catalase 1 296 5.6E-96 T 11-10-2018 IPR007760 Manganese catalase AFK25_07550 526f155bab318e1c28feb47a9b9c8457 298 Gene3D G3DSA:1.20.1260.130 2 297 1.4E-111 T 11-10-2018 AFK25_07550 526f155bab318e1c28feb47a9b9c8457 298 SUPERFAMILY SSF47240 1 293 1.24E-95 T 11-10-2018 IPR009078 Ferritin-like superfamily AFK25_09130 6d08e73c81e58346b7a2ca67db698671 340 Pfam PF14493 Helix-turn-helix domain 245 332 2.2E-23 T 11-10-2018 IPR029491 Helicase Helix-turn-helix domain Reactome: R-HSA-3108214|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473 AFK25_09130 6d08e73c81e58346b7a2ca67db698671 340 PIRSF PIRSF021350 1 340 1.8E-88 T 11-10-2018 IPR008308 Uncharacterised conserved protein UCP021350 AFK25_11455 57205fffe6989dacb2a9d0b802d09862 333 SUPERFAMILY SSF55347 129 297 8.34E-39 T 11-10-2018 AFK25_11455 57205fffe6989dacb2a9d0b802d09862 333 Pfam PF01408 Oxidoreductase family, NAD-binding Rossmann fold 6 121 3.1E-21 T 11-10-2018 IPR000683 Oxidoreductase, N-terminal GO:0016491 AFK25_11455 57205fffe6989dacb2a9d0b802d09862 333 Gene3D G3DSA:3.30.360.10 123 331 3.2E-47 T 11-10-2018 AFK25_11455 57205fffe6989dacb2a9d0b802d09862 333 Gene3D G3DSA:3.40.50.720 1 120 2.2E-35 T 11-10-2018 AFK25_11455 57205fffe6989dacb2a9d0b802d09862 333 SUPERFAMILY SSF51735 2 157 1.41E-47 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_11760 269b055eda4831160d43976f9ad5b702 376 SUPERFAMILY SSF56801 97 340 3.27E-25 T 11-10-2018 AFK25_11760 269b055eda4831160d43976f9ad5b702 376 Pfam PF00501 AMP-binding enzyme 129 254 1.3E-8 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFK25_11760 269b055eda4831160d43976f9ad5b702 376 Gene3D G3DSA:3.40.50.12780 1 290 2.1E-59 T 11-10-2018 AFK25_12185 57412b84a3ad298d57ce57a4f47ba6fb 157 Gene3D G3DSA:3.30.1360.80 1 157 2.6E-62 T 11-10-2018 IPR037005 S-ribosylhomocysteinase (LuxS) superfamily GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 AFK25_12185 57412b84a3ad298d57ce57a4f47ba6fb 157 Pfam PF02664 S-Ribosylhomocysteinase (LuxS) 4 151 2.6E-51 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 AFK25_12185 57412b84a3ad298d57ce57a4f47ba6fb 157 SUPERFAMILY SSF63411 4 151 3.57E-59 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFK25_12185 57412b84a3ad298d57ce57a4f47ba6fb 157 PIRSF PIRSF006160 1 157 1.1E-62 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 AFK25_12185 57412b84a3ad298d57ce57a4f47ba6fb 157 ProDom PD013172 LYASE SYNTHESIS LUXS AUTOINDUCER-2 PRODUCTION AUTOINDUCER S-RIBOSYLHOMOCYSTEINE AI-2 QUORUM SENSING 8 146 4.0E-69 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 AFK25_12185 57412b84a3ad298d57ce57a4f47ba6fb 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 5 23 1.4E-39 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 AFK25_12185 57412b84a3ad298d57ce57a4f47ba6fb 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 78 96 1.4E-39 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 AFK25_12185 57412b84a3ad298d57ce57a4f47ba6fb 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 119 138 1.4E-39 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 AFK25_12185 57412b84a3ad298d57ce57a4f47ba6fb 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 49 67 1.4E-39 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 AFK25_12185 57412b84a3ad298d57ce57a4f47ba6fb 157 PRINTS PR01487 Bacterial autoinducer-2 (AI-2) production protein LuxS signature 28 46 1.4E-39 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 AFK25_12185 57412b84a3ad298d57ce57a4f47ba6fb 157 Hamap MF_00091 S-ribosylhomocysteine lyase [luxS]. 1 157 33.316 T 11-10-2018 IPR003815 S-ribosylhomocysteinase (LuxS) GO:0005506|GO:0009372|GO:0043768 KEGG: 00270+4.4.1.21|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 AFK25_01720 aadc298c0786e2ea644fd7b6dbc087f8 235 Pfam PF01903 CbiX 127 223 1.5E-11 T 11-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 AFK25_01720 aadc298c0786e2ea644fd7b6dbc087f8 235 Pfam PF01903 CbiX 9 113 3.7E-25 T 11-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 AFK25_01720 aadc298c0786e2ea644fd7b6dbc087f8 235 Gene3D G3DSA:3.40.50.1400 120 234 1.6E-17 T 11-10-2018 AFK25_01720 aadc298c0786e2ea644fd7b6dbc087f8 235 Gene3D G3DSA:3.40.50.1400 1 119 3.6E-22 T 11-10-2018 AFK25_01720 aadc298c0786e2ea644fd7b6dbc087f8 235 SUPERFAMILY SSF53800 1 234 6.32E-42 T 11-10-2018 AFK25_11560 94e3a80d23ac21d586cff4ca9b0c0b18 124 SUPERFAMILY SSF56276 3 113 3.73E-40 T 11-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 AFK25_11560 94e3a80d23ac21d586cff4ca9b0c0b18 124 Gene3D G3DSA:3.30.360.110 1 62 2.1E-26 T 11-10-2018 AFK25_11560 94e3a80d23ac21d586cff4ca9b0c0b18 124 Gene3D G3DSA:3.30.160.750 63 123 2.3E-18 T 11-10-2018 AFK25_11560 94e3a80d23ac21d586cff4ca9b0c0b18 124 Pfam PF02675 S-adenosylmethionine decarboxylase 7 112 7.5E-37 T 11-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 AFK25_11560 94e3a80d23ac21d586cff4ca9b0c0b18 124 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 1 116 31.517 T 11-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 AFK25_11560 94e3a80d23ac21d586cff4ca9b0c0b18 124 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 3 112 2.4E-41 T 11-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 AFK25_14155 c5147fcd4b6637414cf7b1709c37ed94 331 Pfam PF07885 Ion channel 13 86 8.2E-16 T 11-10-2018 IPR013099 Potassium channel domain AFK25_14155 c5147fcd4b6637414cf7b1709c37ed94 331 Gene3D G3DSA:1.10.287.70 1 108 1.2E-23 T 11-10-2018 AFK25_14155 c5147fcd4b6637414cf7b1709c37ed94 331 Gene3D G3DSA:3.40.50.720 109 257 6.1E-43 T 11-10-2018 AFK25_14155 c5147fcd4b6637414cf7b1709c37ed94 331 Pfam PF02080 TrkA-C domain 259 326 1.2E-12 T 11-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AFK25_14155 c5147fcd4b6637414cf7b1709c37ed94 331 SUPERFAMILY SSF51735 106 246 1.7E-40 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_14155 c5147fcd4b6637414cf7b1709c37ed94 331 SUPERFAMILY SSF81324 3 129 5.49E-28 T 11-10-2018 AFK25_14155 c5147fcd4b6637414cf7b1709c37ed94 331 SUPERFAMILY SSF116726 249 326 5.23E-19 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFK25_14155 c5147fcd4b6637414cf7b1709c37ed94 331 Gene3D G3DSA:3.30.70.1450 258 331 1.2E-20 T 11-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AFK25_14155 c5147fcd4b6637414cf7b1709c37ed94 331 Pfam PF02254 TrkA-N domain 110 224 8.4E-35 T 11-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AFK25_04110 00d6290529f9a16a1dbfb77da5031888 95 Pfam PF01527 Transposase 3 81 7.3E-18 T 11-10-2018 IPR002514 Transposase IS3/IS911family GO:0003677|GO:0004803|GO:0006313 AFK25_04110 00d6290529f9a16a1dbfb77da5031888 95 SUPERFAMILY SSF46689 1 93 1.38E-21 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_04110 00d6290529f9a16a1dbfb77da5031888 95 Gene3D G3DSA:1.10.10.60 6 93 1.1E-12 T 11-10-2018 AFK25_07900 a6523b875a1312b866cd934c2bce73aa 406 Pfam PF01266 FAD dependent oxidoreductase 30 382 3.7E-50 T 11-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AFK25_07900 a6523b875a1312b866cd934c2bce73aa 406 SUPERFAMILY SSF51905 28 391 5.5E-40 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_07900 a6523b875a1312b866cd934c2bce73aa 406 Gene3D G3DSA:3.30.9.10 123 344 6.7E-66 T 11-10-2018 AFK25_07900 a6523b875a1312b866cd934c2bce73aa 406 Gene3D G3DSA:3.50.50.60 30 385 6.7E-66 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_12765 5124c5b8860922b9b21111482037a8ce 430 SUPERFAMILY SSF53383 1 418 2.93E-128 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_12765 5124c5b8860922b9b21111482037a8ce 430 Pfam PF01053 Cys/Met metabolism PLP-dependent enzyme 4 418 7.8E-144 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFK25_12765 5124c5b8860922b9b21111482037a8ce 430 Gene3D G3DSA:3.40.640.10 1 282 1.0E-103 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_12765 5124c5b8860922b9b21111482037a8ce 430 Gene3D G3DSA:3.90.1150.10 286 428 4.3E-51 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_12765 5124c5b8860922b9b21111482037a8ce 430 PIRSF PIRSF001434 1 421 1.2E-129 T 11-10-2018 IPR000277 Cys/Met metabolism, pyridoxal phosphate-dependent enzyme GO:0030170 Reactome: R-HSA-1614558|Reactome: R-HSA-1614603|Reactome: R-HSA-2408508 AFK25_12765 5124c5b8860922b9b21111482037a8ce 430 TIGRFAM TIGR01326 OAH_OAS_sulfhy: O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase 2 418 4.1E-198 T 11-10-2018 IPR006235 O-acetylhomoserine/O-acetylserine sulfhydrylase GO:0006520|GO:0016765 AFK25_00325 b2374c29926cd3f446445dc3493335fe 202 Pfam PF09578 Spore cortex protein YabQ (Spore_YabQ) 11 87 2.6E-21 T 11-10-2018 IPR019074 Spore cortex biosynthesis protein, YabQ-like AFK25_00325 b2374c29926cd3f446445dc3493335fe 202 TIGRFAM TIGR02893 spore_yabQ: spore cortex biosynthesis protein YabQ 2 129 5.9E-36 T 11-10-2018 IPR014242 Spore cortex biosynthesis protein, YabQ AFK25_08320 c7180ed523a415704c5ba6de09d82fd8 560 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 467 478 - T 11-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFK25_08320 c7180ed523a415704c5ba6de09d82fd8 560 Gene3D G3DSA:3.50.30.80 379 530 2.4E-55 T 11-10-2018 AFK25_08320 c7180ed523a415704c5ba6de09d82fd8 560 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 124 134 - T 11-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFK25_08320 c7180ed523a415704c5ba6de09d82fd8 560 SUPERFAMILY SSF52016 379 558 2.12E-63 T 11-10-2018 AFK25_08320 c7180ed523a415704c5ba6de09d82fd8 560 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 19 559 2.2E-261 T 11-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFK25_08320 c7180ed523a415704c5ba6de09d82fd8 560 Pfam PF00920 Dehydratase family 36 555 3.8E-230 T 11-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFK25_08320 c7180ed523a415704c5ba6de09d82fd8 560 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 6 559 47.748 T 11-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFK25_08320 c7180ed523a415704c5ba6de09d82fd8 560 SUPERFAMILY SSF143975 4 378 4.58E-142 T 11-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AFK25_10040 74409e81ea4efdbb5a2157a152034931 123 Pfam PF03960 ArsC family 23 111 4.8E-17 T 11-10-2018 IPR006660 Arsenate reductase-like AFK25_10040 74409e81ea4efdbb5a2157a152034931 123 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 2 112 2.5E-35 T 11-10-2018 IPR006504 Transcriptional regulator Spx/MgsR AFK25_10040 74409e81ea4efdbb5a2157a152034931 123 Gene3D G3DSA:3.40.30.10 1 119 8.6E-36 T 11-10-2018 AFK25_10040 74409e81ea4efdbb5a2157a152034931 123 SUPERFAMILY SSF52833 1 113 3.98E-31 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_11830 3a69675de34126b9614014d1a6414db9 161 Pfam PF13185 GAF domain 65 155 8.7E-13 T 11-10-2018 IPR003018 GAF domain GO:0005515 AFK25_11830 3a69675de34126b9614014d1a6414db9 161 SUPERFAMILY SSF55781 11 156 2.18E-45 T 11-10-2018 AFK25_11830 3a69675de34126b9614014d1a6414db9 161 ProSitePatterns PS01320 Uncharacterized protein family UPF0067 signature. 98 115 - T 11-10-2018 IPR000614 Free Met sulfoxide reductase conserved site AFK25_11830 3a69675de34126b9614014d1a6414db9 161 Gene3D G3DSA:3.30.450.40 2 159 1.5E-66 T 11-10-2018 IPR029016 GAF-like domain superfamily AFK25_11830 3a69675de34126b9614014d1a6414db9 161 SMART SM00065 31 160 2.7E-4 T 11-10-2018 IPR003018 GAF domain GO:0005515 AFK25_08910 657e0cdbc7f0be442b2e099a9ac00241 126 SUPERFAMILY SSF55298 2 124 3.53E-47 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFK25_08910 657e0cdbc7f0be442b2e099a9ac00241 126 ProDom PD031888 MUTASE CHORISMATE AROH THE CLASS ISOMERASE TRANSCRIPTION BIOSYNTHESIS CM 3D-STRUCTURE 8 126 1.0E-40 T 11-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFK25_08910 657e0cdbc7f0be442b2e099a9ac00241 126 Gene3D G3DSA:3.30.1330.40 1 126 5.6E-50 T 11-10-2018 IPR035959 RutC-like superfamily Reactome: R-HSA-8849175 AFK25_08910 657e0cdbc7f0be442b2e099a9ac00241 126 Pfam PF07736 Chorismate mutase type I 2 118 1.9E-47 T 11-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFK25_08910 657e0cdbc7f0be442b2e099a9ac00241 126 PIRSF PIRSF005965 1 124 6.7E-50 T 11-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFK25_08910 657e0cdbc7f0be442b2e099a9ac00241 126 TIGRFAM TIGR01796 CM_mono_aroH: chorismate mutase 2 118 7.5E-49 T 11-10-2018 IPR008243 Chorismate mutase, AroH class KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AFK25_11540 c427712054ac7756a4c50bceea352956 310 Pfam PF07319 Primosomal protein DnaI N-terminus 1 96 1.3E-30 T 11-10-2018 IPR009928 Primosomal DnaI, N-terminal AFK25_11540 c427712054ac7756a4c50bceea352956 310 Gene3D G3DSA:3.40.50.300 106 301 1.2E-49 T 11-10-2018 AFK25_11540 c427712054ac7756a4c50bceea352956 310 Pfam PF01695 IstB-like ATP binding protein 157 273 1.2E-10 T 11-10-2018 IPR002611 IstB-like ATP-binding protein GO:0005524 AFK25_11540 c427712054ac7756a4c50bceea352956 310 SUPERFAMILY SSF52540 149 272 1.05E-16 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_11540 c427712054ac7756a4c50bceea352956 310 SMART SM00382 158 305 0.002 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_08955 1d928bcc8677bc5f394ebee6b6287978 187 TIGRFAM TIGR00063 folE: GTP cyclohydrolase I 9 187 5.0E-79 T 11-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 AFK25_08955 1d928bcc8677bc5f394ebee6b6287978 187 Gene3D G3DSA:1.10.286.10 1 54 7.8E-25 T 11-10-2018 AFK25_08955 1d928bcc8677bc5f394ebee6b6287978 187 Gene3D G3DSA:3.30.1130.10 55 187 1.2E-61 T 11-10-2018 AFK25_08955 1d928bcc8677bc5f394ebee6b6287978 187 Pfam PF01227 GTP cyclohydrolase I 9 186 1.9E-80 T 11-10-2018 IPR020602 GTP cyclohydrolase I domain KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 AFK25_08955 1d928bcc8677bc5f394ebee6b6287978 187 Hamap MF_00223 GTP cyclohydrolase 1 [folE]. 5 187 42.258 T 11-10-2018 IPR001474 GTP cyclohydrolase I GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 AFK25_08955 1d928bcc8677bc5f394ebee6b6287978 187 SUPERFAMILY SSF55620 3 187 4.74E-78 T 11-10-2018 AFK25_08955 1d928bcc8677bc5f394ebee6b6287978 187 ProSitePatterns PS00859 GTP cyclohydrolase I signature 1. 65 81 - T 11-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 AFK25_08955 1d928bcc8677bc5f394ebee6b6287978 187 ProSitePatterns PS00860 GTP cyclohydrolase I signature 2. 114 124 - T 11-10-2018 IPR018234 GTP cyclohydrolase I, conserved site GO:0003934|GO:0005737|GO:0046654 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852|Reactome: R-HSA-1474151 AFK25_07085 494e4860bb59af05c1fa5ce33b22affe 410 PRINTS PR00173 Glutamate-aspartate symporter signature 5 25 1.3E-52 T 11-10-2018 AFK25_07085 494e4860bb59af05c1fa5ce33b22affe 410 PRINTS PR00173 Glutamate-aspartate symporter signature 48 68 1.3E-52 T 11-10-2018 AFK25_07085 494e4860bb59af05c1fa5ce33b22affe 410 PRINTS PR00173 Glutamate-aspartate symporter signature 78 103 1.3E-52 T 11-10-2018 AFK25_07085 494e4860bb59af05c1fa5ce33b22affe 410 PRINTS PR00173 Glutamate-aspartate symporter signature 290 316 1.3E-52 T 11-10-2018 AFK25_07085 494e4860bb59af05c1fa5ce33b22affe 410 PRINTS PR00173 Glutamate-aspartate symporter signature 325 344 1.3E-52 T 11-10-2018 AFK25_07085 494e4860bb59af05c1fa5ce33b22affe 410 PRINTS PR00173 Glutamate-aspartate symporter signature 352 372 1.3E-52 T 11-10-2018 AFK25_07085 494e4860bb59af05c1fa5ce33b22affe 410 PRINTS PR00173 Glutamate-aspartate symporter signature 188 207 1.3E-52 T 11-10-2018 AFK25_07085 494e4860bb59af05c1fa5ce33b22affe 410 SUPERFAMILY SSF118215 4 399 8.24E-125 T 11-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 AFK25_07085 494e4860bb59af05c1fa5ce33b22affe 410 Gene3D G3DSA:1.10.3860.10 1 404 7.6E-144 T 11-10-2018 IPR036458 Sodium:dicarboxylate symporter superfamily GO:0015293|GO:0016021 AFK25_07085 494e4860bb59af05c1fa5ce33b22affe 410 Pfam PF00375 Sodium:dicarboxylate symporter family 3 397 1.8E-137 T 11-10-2018 IPR001991 Sodium:dicarboxylate symporter GO:0015293|GO:0016021 AFK25_00910 8f9f2d2351ec1ddec6ed72fea1060101 149 SUPERFAMILY SSF54637 3 138 3.96E-44 T 11-10-2018 IPR029069 HotDog domain superfamily AFK25_00910 8f9f2d2351ec1ddec6ed72fea1060101 149 Pfam PF03061 Thioesterase superfamily 25 96 1.5E-17 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFK25_00910 8f9f2d2351ec1ddec6ed72fea1060101 149 Gene3D G3DSA:3.10.129.10 1 149 3.3E-49 T 11-10-2018 AFK25_02610 a34c9c75e38d389b8c6854275b6c218f 142 Hamap MF_00287 Probable disulfide formation protein [bdbC]. 1 137 22.867 T 11-10-2018 IPR012187 Disulphide bond formation protein BdbC AFK25_02610 a34c9c75e38d389b8c6854275b6c218f 142 PIRSF PIRSF036659 1 140 1.8E-52 T 11-10-2018 IPR012187 Disulphide bond formation protein BdbC AFK25_02610 a34c9c75e38d389b8c6854275b6c218f 142 SUPERFAMILY SSF158442 8 131 5.89E-30 T 11-10-2018 IPR023380 DsbB-like superfamily AFK25_02610 a34c9c75e38d389b8c6854275b6c218f 142 Gene3D G3DSA:1.20.1550.10 1 117 2.8E-12 T 11-10-2018 IPR023380 DsbB-like superfamily AFK25_02610 a34c9c75e38d389b8c6854275b6c218f 142 Pfam PF02600 Disulfide bond formation protein DsbB 8 110 2.6E-11 T 11-10-2018 IPR003752 Disulphide bond formation protein DsbB/BdbC GO:0015035|GO:0016020 AFK25_04330 f0cfb1719251f8998b65e577b17a3497 593 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 6 550 9.3E-113 T 11-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 AFK25_04330 f0cfb1719251f8998b65e577b17a3497 593 Pfam PF02652 L-lactate permease 8 550 2.1E-117 T 11-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 AFK25_00480 3b3bcfa043db70556dcedf9aa3b78a4d 228 Pfam PF01128 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 4 223 1.2E-77 T 11-10-2018 IPR034683 Cytidylyltransferase IspD/TarI GO:0070567 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 AFK25_00480 3b3bcfa043db70556dcedf9aa3b78a4d 228 TIGRFAM TIGR00453 ispD: 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 5 222 3.4E-78 T 11-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 AFK25_00480 3b3bcfa043db70556dcedf9aa3b78a4d 228 ProSitePatterns PS01295 4-diphosphocytidyl-2C-methyl-D-erythritol synthase signature. 100 107 - T 11-10-2018 IPR018294 4-diphosphocytidyl-2C-methyl-D-erythritol synthase, conserved site GO:0003824|GO:0008299 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 AFK25_00480 3b3bcfa043db70556dcedf9aa3b78a4d 228 Gene3D G3DSA:3.90.550.10 1 227 1.3E-80 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_00480 3b3bcfa043db70556dcedf9aa3b78a4d 228 Hamap MF_00108 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase [ispD]. 2 222 43.156 T 11-10-2018 IPR001228 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase GO:0008299|GO:0050518 KEGG: 00900+2.7.7.60|MetaCyc: PWY-7560 AFK25_00480 3b3bcfa043db70556dcedf9aa3b78a4d 228 SUPERFAMILY SSF53448 3 222 3.6E-62 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_04090 29555e9d33d783921d56260a2187a03d 221 SUPERFAMILY SSF161098 12 204 8.11E-44 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_04090 29555e9d33d783921d56260a2187a03d 221 Gene3D G3DSA:1.10.3720.10 12 221 4.3E-49 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_04090 29555e9d33d783921d56260a2187a03d 221 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 35 221 6.5E-21 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_05190 9243e0e86596af902bc266f5057bfd7c 118 Hamap MF_00910 Cell division protein FtsL [ftsL]. 35 117 15.141 T 11-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 AFK25_05190 9243e0e86596af902bc266f5057bfd7c 118 Pfam PF04977 Septum formation initiator 42 116 1.4E-14 T 11-10-2018 IPR007060 Septum formation initiator FtsL/DivIC AFK25_05190 9243e0e86596af902bc266f5057bfd7c 118 TIGRFAM TIGR02209 ftsL_broad: cell division protein FtsL 35 117 2.4E-20 T 11-10-2018 IPR011922 Cell division protein FtsL GO:0016021|GO:0051301 AFK25_11915 507160210c2c17acd8cb59b77cd5a8b0 369 Gene3D G3DSA:3.90.1170.20 11 118 1.7E-17 T 11-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 AFK25_11915 507160210c2c17acd8cb59b77cd5a8b0 369 SUPERFAMILY SSF51690 128 353 1.2E-45 T 11-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 AFK25_11915 507160210c2c17acd8cb59b77cd5a8b0 369 PIRSF PIRSF000484 15 85 3.5E-8 T 11-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 AFK25_11915 507160210c2c17acd8cb59b77cd5a8b0 369 PIRSF PIRSF000484 76 350 7.5E-57 T 11-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 AFK25_11915 507160210c2c17acd8cb59b77cd5a8b0 369 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 46 114 4.2E-8 T 11-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 AFK25_11915 507160210c2c17acd8cb59b77cd5a8b0 369 Gene3D G3DSA:3.20.20.70 120 333 8.1E-62 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_11915 507160210c2c17acd8cb59b77cd5a8b0 369 SUPERFAMILY SSF54675 18 128 2.16E-24 T 11-10-2018 AFK25_12170 bdbb923814704d12a3a63aba2a0c4099 157 PRINTS PR00502 NUDIX hydrolase family signature 62 77 3.5E-9 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFK25_12170 bdbb923814704d12a3a63aba2a0c4099 157 PRINTS PR00502 NUDIX hydrolase family signature 48 62 3.5E-9 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFK25_12170 bdbb923814704d12a3a63aba2a0c4099 157 ProSitePatterns PS00893 Nudix box signature. 53 74 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFK25_12170 bdbb923814704d12a3a63aba2a0c4099 157 Gene3D G3DSA:3.90.79.10 1 157 3.2E-47 T 11-10-2018 AFK25_12170 bdbb923814704d12a3a63aba2a0c4099 157 Pfam PF00293 NUDIX domain 29 101 7.8E-17 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFK25_12170 bdbb923814704d12a3a63aba2a0c4099 157 SUPERFAMILY SSF55811 7 99 1.9E-23 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFK25_12170 bdbb923814704d12a3a63aba2a0c4099 157 TIGRFAM TIGR02705 nudix_YtkD: nucleoside triphosphatase YtkD 3 156 3.0E-66 T 11-10-2018 IPR014078 Nucleoside triphosphatase YtkD MetaCyc: PWY-6502 AFK25_04455 ba2bbbd6f0e059f8076dd98a29e93e61 215 Gene3D G3DSA:1.10.357.10 14 215 7.6E-36 T 11-10-2018 AFK25_04455 ba2bbbd6f0e059f8076dd98a29e93e61 215 SUPERFAMILY SSF48498 103 214 6.99E-12 T 11-10-2018 IPR036271 Tetracyclin repressor-like, C-terminal domain superfamily AFK25_04455 ba2bbbd6f0e059f8076dd98a29e93e61 215 Pfam PF00440 Bacterial regulatory proteins, tetR family 25 71 1.2E-18 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_04455 ba2bbbd6f0e059f8076dd98a29e93e61 215 SUPERFAMILY SSF46689 19 76 5.64E-17 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_04455 ba2bbbd6f0e059f8076dd98a29e93e61 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 46 69 8.8E-13 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_04455 ba2bbbd6f0e059f8076dd98a29e93e61 215 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 25 38 8.8E-13 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_07030 3a071acbe487bb9df67ae56a242e7d4f 277 Gene3D G3DSA:3.40.50.10090 23 266 2.1E-76 T 11-10-2018 AFK25_07030 3a071acbe487bb9df67ae56a242e7d4f 277 SUPERFAMILY SSF69618 17 276 7.98E-56 T 11-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFK25_07030 3a071acbe487bb9df67ae56a242e7d4f 277 Gene3D G3DSA:3.40.50.10090 47 182 2.1E-76 T 11-10-2018 AFK25_07030 3a071acbe487bb9df67ae56a242e7d4f 277 Pfam PF02602 Uroporphyrinogen-III synthase HemD 29 267 1.2E-40 T 11-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AFK25_08055 52a20a6edbe6240f8fdab71ad164812b 446 Pfam PF13520 Amino acid permease 10 416 9.0E-60 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFK25_08055 52a20a6edbe6240f8fdab71ad164812b 446 PIRSF PIRSF006060 1 446 1.3E-78 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFK25_08055 52a20a6edbe6240f8fdab71ad164812b 446 Gene3D G3DSA:1.20.1740.10 4 446 4.0E-93 T 11-10-2018 AFK25_02480 cb847e0bbbd5dcca0f42726c3f242f41 187 Pfam PF09684 Phage tail protein (Tail_P2_I) 29 153 6.8E-30 T 11-10-2018 IPR006521 Tail protein I AFK25_02480 cb847e0bbbd5dcca0f42726c3f242f41 187 TIGRFAM TIGR01634 tail_P2_I: phage tail protein I 44 148 8.0E-11 T 11-10-2018 IPR006521 Tail protein I AFK25_11415 29fc5bb3d77500a88653b4b52d2efde1 282 SUPERFAMILY SSF161098 11 282 1.12E-63 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_11415 29fc5bb3d77500a88653b4b52d2efde1 282 Gene3D G3DSA:1.10.3720.10 5 272 4.6E-55 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_11415 29fc5bb3d77500a88653b4b52d2efde1 282 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 95 267 7.0E-21 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_06870 6101027ab3b77632071dc219c070cb52 100 Gene3D G3DSA:3.10.350.10 22 96 3.1E-10 T 11-10-2018 IPR036779 LysM domain superfamily AFK25_06870 6101027ab3b77632071dc219c070cb52 100 SMART SM00257 34 85 0.0086 T 11-10-2018 IPR018392 LysM domain AFK25_06870 6101027ab3b77632071dc219c070cb52 100 Pfam PF01476 LysM domain 35 85 4.4E-8 T 11-10-2018 IPR018392 LysM domain AFK25_06870 6101027ab3b77632071dc219c070cb52 100 SUPERFAMILY SSF54106 36 85 5.36E-5 T 11-10-2018 AFK25_09120 470dd2ece212a4dfb582a236d5b5aa5b 196 Pfam PF02517 CAAX protease self-immunity 99 179 1.5E-9 T 11-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 AFK25_00335 38a869dc9a8cf7bec2c316ab6e1d8e53 130 Pfam PF00575 S1 RNA binding domain 4 74 7.7E-21 T 11-10-2018 IPR003029 S1 domain GO:0003676 AFK25_00335 38a869dc9a8cf7bec2c316ab6e1d8e53 130 Gene3D G3DSA:2.40.50.140 1 84 1.7E-28 T 11-10-2018 AFK25_00335 38a869dc9a8cf7bec2c316ab6e1d8e53 130 SMART SM00316 4 74 1.1E-26 T 11-10-2018 IPR022967 RNA-binding domain, S1 AFK25_00335 38a869dc9a8cf7bec2c316ab6e1d8e53 130 SUPERFAMILY SSF50249 4 80 1.99E-24 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_05165 df2f02f82f87d93c8ef44735964eb227 148 Pfam PF13921 Myb-like DNA-binding domain 7 61 6.7E-5 T 11-10-2018 AFK25_05165 df2f02f82f87d93c8ef44735964eb227 148 Gene3D G3DSA:1.10.10.60 6 83 7.3E-7 T 11-10-2018 AFK25_05165 df2f02f82f87d93c8ef44735964eb227 148 SUPERFAMILY SSF46689 5 61 1.1E-5 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_05165 df2f02f82f87d93c8ef44735964eb227 148 TIGRFAM TIGR02894 DNA_bind_RsfA: transcription factor, RsfA family 2 148 5.0E-56 T 11-10-2018 IPR014243 Transcription factor, RsfA AFK25_12910 abe48a544bfefd5db0f2d156cae3d9d0 394 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 15 25 - T 11-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12910 abe48a544bfefd5db0f2d156cae3d9d0 394 SUPERFAMILY SSF53748 1 393 5.3E-168 T 11-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12910 abe48a544bfefd5db0f2d156cae3d9d0 394 Pfam PF00162 Phosphoglycerate kinase 6 383 2.9E-170 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12910 abe48a544bfefd5db0f2d156cae3d9d0 394 Gene3D G3DSA:3.40.50.1260 8 391 1.2E-169 T 11-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12910 abe48a544bfefd5db0f2d156cae3d9d0 394 Gene3D G3DSA:3.40.50.1260 169 383 1.2E-169 T 11-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12910 abe48a544bfefd5db0f2d156cae3d9d0 394 PRINTS PR00477 Phosphoglycerate kinase family signature 137 159 2.5E-101 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12910 abe48a544bfefd5db0f2d156cae3d9d0 394 PRINTS PR00477 Phosphoglycerate kinase family signature 312 337 2.5E-101 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12910 abe48a544bfefd5db0f2d156cae3d9d0 394 PRINTS PR00477 Phosphoglycerate kinase family signature 346 357 2.5E-101 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12910 abe48a544bfefd5db0f2d156cae3d9d0 394 PRINTS PR00477 Phosphoglycerate kinase family signature 10 26 2.5E-101 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12910 abe48a544bfefd5db0f2d156cae3d9d0 394 PRINTS PR00477 Phosphoglycerate kinase family signature 31 53 2.5E-101 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12910 abe48a544bfefd5db0f2d156cae3d9d0 394 PRINTS PR00477 Phosphoglycerate kinase family signature 167 189 2.5E-101 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12910 abe48a544bfefd5db0f2d156cae3d9d0 394 PRINTS PR00477 Phosphoglycerate kinase family signature 190 209 2.5E-101 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12910 abe48a544bfefd5db0f2d156cae3d9d0 394 PRINTS PR00477 Phosphoglycerate kinase family signature 369 386 2.5E-101 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12910 abe48a544bfefd5db0f2d156cae3d9d0 394 PRINTS PR00477 Phosphoglycerate kinase family signature 109 124 2.5E-101 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12910 abe48a544bfefd5db0f2d156cae3d9d0 394 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 393 43.768 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_12910 abe48a544bfefd5db0f2d156cae3d9d0 394 PIRSF PIRSF000724 1 394 4.4E-162 T 11-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_04210 d81502a1b7ec4ae3ae79a70a69abcec9 208 Gene3D G3DSA:3.40.50.360 1 208 4.2E-67 T 11-10-2018 IPR029039 Flavoprotein-like superfamily AFK25_04210 d81502a1b7ec4ae3ae79a70a69abcec9 208 SUPERFAMILY SSF52218 1 208 3.39E-55 T 11-10-2018 IPR029039 Flavoprotein-like superfamily AFK25_04210 d81502a1b7ec4ae3ae79a70a69abcec9 208 Hamap MF_01216 FMN-dependent NADH-azoreductase [azoR]. 2 208 30.256 T 11-10-2018 IPR023048 NADH-azoreductase, FMN-dependent GO:0016661|GO:0055114 AFK25_04210 d81502a1b7ec4ae3ae79a70a69abcec9 208 Pfam PF02525 Flavodoxin-like fold 3 203 3.7E-50 T 11-10-2018 IPR003680 Flavodoxin-like fold AFK25_12870 3a389a6d4d74b20e1962c5a0544075d7 245 Pfam PF12146 Serine aminopeptidase, S33 16 228 1.6E-16 T 11-10-2018 IPR022742 Serine aminopeptidase, S33 AFK25_12870 3a389a6d4d74b20e1962c5a0544075d7 245 SUPERFAMILY SSF53474 15 243 8.04E-36 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold AFK25_12870 3a389a6d4d74b20e1962c5a0544075d7 245 Gene3D G3DSA:3.40.50.1820 1 245 1.4E-63 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold AFK25_12870 3a389a6d4d74b20e1962c5a0544075d7 245 PIRSF PIRSF017388 1 245 3.4E-96 T 11-10-2018 IPR012354 Esterase/lipase GO:0052689 AFK25_04375 65bf922c2027e60e42f59c91c5facea9 370 Pfam PF13407 Periplasmic binding protein domain 65 315 3.5E-40 T 11-10-2018 IPR025997 Periplasmic binding protein AFK25_04375 65bf922c2027e60e42f59c91c5facea9 370 Gene3D G3DSA:3.40.50.2300 57 322 7.2E-90 T 11-10-2018 AFK25_04375 65bf922c2027e60e42f59c91c5facea9 370 Gene3D G3DSA:3.40.50.2300 156 328 7.2E-90 T 11-10-2018 AFK25_04375 65bf922c2027e60e42f59c91c5facea9 370 SUPERFAMILY SSF53822 53 332 1.21E-56 T 11-10-2018 IPR028082 Periplasmic binding protein-like I AFK25_06875 33bc132d4e803accbb2f999a5856c2b3 226 SUPERFAMILY SSF53041 1 148 1.02E-27 T 11-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 AFK25_06875 33bc132d4e803accbb2f999a5856c2b3 226 SMART SM00857 3 149 5.7E-37 T 11-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFK25_06875 33bc132d4e803accbb2f999a5856c2b3 226 Gene3D G3DSA:3.40.50.1390 1 153 1.7E-29 T 11-10-2018 AFK25_06875 33bc132d4e803accbb2f999a5856c2b3 226 Pfam PF00239 Resolvase, N terminal domain 3 147 3.7E-28 T 11-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFK25_13925 1dca0381a1efbb38236bfc938ca60b00 207 TIGRFAM TIGR02837 spore_II_R: stage II sporulation protein R 3 166 1.3E-60 T 11-10-2018 IPR014202 Sporulation stage II, protein R AFK25_13925 1dca0381a1efbb38236bfc938ca60b00 207 Pfam PF09551 Stage II sporulation protein R (spore_II_R) 36 160 9.7E-48 T 11-10-2018 IPR014202 Sporulation stage II, protein R AFK25_07460 cb5908958c6ca160fb639220ec659f97 198 SUPERFAMILY SSF53098 70 194 4.17E-30 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_07460 cb5908958c6ca160fb639220ec659f97 198 SUPERFAMILY SSF55658 2 47 7.32E-14 T 11-10-2018 IPR009027 Ribosomal protein L9/RNase H1, N-terminal AFK25_07460 cb5908958c6ca160fb639220ec659f97 198 PIRSF PIRSF037839 1 198 7.5E-88 T 11-10-2018 IPR017290 Ribonuclease H, Bacteroides-type GO:0004523 AFK25_07460 cb5908958c6ca160fb639220ec659f97 198 Gene3D G3DSA:3.30.420.10 64 196 3.4E-55 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFK25_07460 cb5908958c6ca160fb639220ec659f97 198 Pfam PF00075 RNase H 71 164 1.6E-7 T 11-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 AFK25_07460 cb5908958c6ca160fb639220ec659f97 198 Gene3D G3DSA:3.40.970.10 1 50 4.0E-17 T 11-10-2018 IPR037056 Ribonuclease H1, N-terminal domain superfamily AFK25_07460 cb5908958c6ca160fb639220ec659f97 198 Pfam PF01693 Caulimovirus viroplasmin 3 45 2.3E-19 T 11-10-2018 IPR011320 Ribonuclease H1, N-terminal AFK25_09870 145f4bab1fa22de3fcdb32f52ce68ed9 188 TIGRFAM TIGR02830 spore_III_AG: stage III sporulation protein AG 9 188 2.7E-64 T 11-10-2018 IPR014195 Sporulation stage III, protein AG AFK25_08615 c182c4487d53f638a7b72c3079908208 309 Gene3D G3DSA:3.40.50.1980 141 308 1.6E-59 T 11-10-2018 AFK25_08615 c182c4487d53f638a7b72c3079908208 309 SUPERFAMILY SSF53807 42 302 5.49E-52 T 11-10-2018 AFK25_08615 c182c4487d53f638a7b72c3079908208 309 Pfam PF01497 Periplasmic binding protein 59 283 1.5E-30 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain AFK25_08615 c182c4487d53f638a7b72c3079908208 309 Gene3D G3DSA:3.40.50.1980 51 140 1.5E-25 T 11-10-2018 AFK25_11890 e7af81478c6c506673fdd30bd4a7882a 371 Pfam PF02073 Thermophilic metalloprotease (M29) 3 337 5.0E-64 T 11-10-2018 IPR000787 Peptidase M29 GO:0004177|GO:0006508 AFK25_11890 e7af81478c6c506673fdd30bd4a7882a 371 SUPERFAMILY SSF144052 1 360 5.75E-120 T 11-10-2018 AFK25_11890 e7af81478c6c506673fdd30bd4a7882a 371 Gene3D G3DSA:3.40.1830.10 2 165 3.4E-16 T 11-10-2018 IPR035097 Peptidase M29, N-terminal AFK25_07570 6a524dc70795bb89ecbcd7d79286ae43 446 TIGRFAM TIGR00797 matE: MATE efflux family protein 20 421 6.4E-98 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFK25_07570 6a524dc70795bb89ecbcd7d79286ae43 446 Pfam PF01554 MatE 247 408 1.1E-34 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFK25_07570 6a524dc70795bb89ecbcd7d79286ae43 446 Pfam PF01554 MatE 20 178 4.1E-33 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFK25_07570 6a524dc70795bb89ecbcd7d79286ae43 446 PIRSF PIRSF006603 1 446 3.5E-69 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFK25_07400 c1d052f6be57c5ef48175d3713ff41fe 126 SUPERFAMILY SSF54593 3 122 3.26E-33 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFK25_07400 c1d052f6be57c5ef48175d3713ff41fe 126 Pfam PF06983 3-demethylubiquinone-9 3-methyltransferase 3 121 3.8E-33 T 11-10-2018 IPR028973 PhnB-like AFK25_07400 c1d052f6be57c5ef48175d3713ff41fe 126 PIRSF PIRSF021700 1 125 2.3E-35 T 11-10-2018 IPR009725 Predicted 3-demethylubiquinone-9 3-methyltransferase AFK25_07400 c1d052f6be57c5ef48175d3713ff41fe 126 Gene3D G3DSA:3.30.720.100 7 65 6.6E-16 T 11-10-2018 AFK25_07400 c1d052f6be57c5ef48175d3713ff41fe 126 Gene3D G3DSA:3.30.720.110 66 124 1.3E-30 T 11-10-2018 AFK25_06080 2e3820cb2253b00f7bd5c000dd04119c 577 SUPERFAMILY SSF53335 41 421 3.91E-58 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_06080 2e3820cb2253b00f7bd5c000dd04119c 577 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 101 120 8.2E-17 T 11-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 AFK25_06080 2e3820cb2253b00f7bd5c000dd04119c 577 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 350 372 8.2E-17 T 11-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 AFK25_06080 2e3820cb2253b00f7bd5c000dd04119c 577 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 67 79 8.2E-17 T 11-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 AFK25_06080 2e3820cb2253b00f7bd5c000dd04119c 577 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 373 387 8.2E-17 T 11-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 AFK25_06080 2e3820cb2253b00f7bd5c000dd04119c 577 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 70 76 - T 11-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AFK25_06080 2e3820cb2253b00f7bd5c000dd04119c 577 Pfam PF01555 DNA methylase 67 405 2.2E-42 T 11-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 AFK25_06080 2e3820cb2253b00f7bd5c000dd04119c 577 PIRSF PIRSF015855 3 576 1.3E-98 T 11-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 AFK25_02980 eea6a7edd65c630933a9ce2523acd14e 264 SMART SM00382 31 233 1.3E-9 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_02980 eea6a7edd65c630933a9ce2523acd14e 264 SUPERFAMILY SSF52540 2 235 1.43E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_02980 eea6a7edd65c630933a9ce2523acd14e 264 Gene3D G3DSA:3.40.50.300 1 261 1.1E-60 T 11-10-2018 AFK25_02980 eea6a7edd65c630933a9ce2523acd14e 264 ProSitePatterns PS00211 ABC transporters family signature. 149 163 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_02980 eea6a7edd65c630933a9ce2523acd14e 264 Pfam PF00005 ABC transporter 22 177 2.6E-29 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_10680 063754f529b9fadfaf65e855c5fafb4a 88 Hamap MF_01507 UPF0297 protein . 1 85 28.131 T 11-10-2018 IPR009309 Uncharacterised protein family UPF0297 AFK25_10680 063754f529b9fadfaf65e855c5fafb4a 88 PIRSF PIRSF037258 1 88 4.5E-45 T 11-10-2018 IPR009309 Uncharacterised protein family UPF0297 AFK25_10680 063754f529b9fadfaf65e855c5fafb4a 88 Pfam PF06135 Bacterial protein of unknown function (DUF965) 5 82 1.9E-37 T 11-10-2018 IPR009309 Uncharacterised protein family UPF0297 AFK25_00675 77a24a07972ce9b51bde7e0386fd487f 132 ProSitePatterns PS00053 Ribosomal protein S8 signature. 102 119 - T 11-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00675 77a24a07972ce9b51bde7e0386fd487f 132 Hamap MF_01302_B 30S ribosomal protein S8 [rpsH]. 2 132 33.449 T 11-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00675 77a24a07972ce9b51bde7e0386fd487f 132 Gene3D G3DSA:3.30.1370.30 4 74 7.4E-35 T 11-10-2018 AFK25_00675 77a24a07972ce9b51bde7e0386fd487f 132 SUPERFAMILY SSF56047 2 132 6.15E-51 T 11-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00675 77a24a07972ce9b51bde7e0386fd487f 132 Gene3D G3DSA:3.30.1490.10 75 132 4.6E-28 T 11-10-2018 AFK25_00675 77a24a07972ce9b51bde7e0386fd487f 132 Pfam PF00410 Ribosomal protein S8 5 132 1.6E-55 T 11-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_13575 20ea43b3db5c1a6b397da9558ee555c7 702 SUPERFAMILY SSF58104 365 700 3.53E-63 T 11-10-2018 AFK25_13575 20ea43b3db5c1a6b397da9558ee555c7 702 Gene3D G3DSA:1.10.287.950 397 701 1.8E-64 T 11-10-2018 AFK25_13575 20ea43b3db5c1a6b397da9558ee555c7 702 SMART SM00304 345 397 1.5E-4 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_13575 20ea43b3db5c1a6b397da9558ee555c7 702 SMART SM00283 405 701 2.6E-61 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_13575 20ea43b3db5c1a6b397da9558ee555c7 702 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 471 652 1.2E-41 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_08060 62f7445a730d097e96f4804d7d10f60c 322 Pfam PF08349 Protein of unknown function (DUF1722) 191 307 7.2E-42 T 11-10-2018 IPR013560 Domain of unknown function DUF1722 AFK25_08060 62f7445a730d097e96f4804d7d10f60c 322 Pfam PF04463 Protein of unknown function (DUF523) 9 149 1.3E-35 T 11-10-2018 IPR007553 Domain of unknown function DUF523 AFK25_08060 62f7445a730d097e96f4804d7d10f60c 322 PIRSF PIRSF037004 1 316 3.6E-117 T 11-10-2018 IPR017087 Uncharacterised conserved protein UCP037004 AFK25_06490 865807b9258ac632ba21e329ab2fd6a6 381 Pfam PF01232 Mannitol dehydrogenase Rossmann domain 2 124 1.3E-28 T 11-10-2018 IPR013131 Mannitol dehydrogenase, N-terminal GO:0016491|GO:0055114 AFK25_06490 865807b9258ac632ba21e329ab2fd6a6 381 SUPERFAMILY SSF51735 3 202 1.58E-48 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_06490 865807b9258ac632ba21e329ab2fd6a6 381 PRINTS PR00084 Mannitol dehydrogenase signature 151 164 5.1E-18 T 11-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 AFK25_06490 865807b9258ac632ba21e329ab2fd6a6 381 PRINTS PR00084 Mannitol dehydrogenase signature 169 184 5.1E-18 T 11-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 AFK25_06490 865807b9258ac632ba21e329ab2fd6a6 381 PRINTS PR00084 Mannitol dehydrogenase signature 3 13 5.1E-18 T 11-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 AFK25_06490 865807b9258ac632ba21e329ab2fd6a6 381 PRINTS PR00084 Mannitol dehydrogenase signature 115 128 5.1E-18 T 11-10-2018 IPR000669 Mannitol dehydrogenase GO:0003824|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 AFK25_06490 865807b9258ac632ba21e329ab2fd6a6 381 Hamap MF_00196 Mannitol-1-phosphate 5-dehydrogenase [mtlD]. 1 378 39.882 T 11-10-2018 IPR023028 Mannitol-1-phosphate 5-dehydrogenase GO:0008926|GO:0019594|GO:0055114 KEGG: 00051+1.1.1.17|MetaCyc: PWY-6531 AFK25_06490 865807b9258ac632ba21e329ab2fd6a6 381 Gene3D G3DSA:3.40.50.720 2 204 2.5E-75 T 11-10-2018 AFK25_06490 865807b9258ac632ba21e329ab2fd6a6 381 Gene3D G3DSA:1.10.1040.10 206 379 8.5E-59 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFK25_06490 865807b9258ac632ba21e329ab2fd6a6 381 Pfam PF08125 Mannitol dehydrogenase C-terminal domain 150 367 2.1E-52 T 11-10-2018 IPR013118 Mannitol dehydrogenase, C-terminal GO:0016491|GO:0050662|GO:0055114 AFK25_06490 865807b9258ac632ba21e329ab2fd6a6 381 SUPERFAMILY SSF48179 203 373 1.53E-41 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFK25_14105 b3d813e8b1f73515bfa4f8b0b51ecf6d 202 Pfam PF13338 Transcriptional regulator, AbiEi antitoxin 8 54 2.0E-10 T 11-10-2018 IPR025159 Transcriptional regulator, AbiEi antitoxin AFK25_14375 6fa2c0de931dabee855c027df82139db 212 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_14375 6fa2c0de931dabee855c027df82139db 212 SMART SM00382 28 207 3.7E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_14375 6fa2c0de931dabee855c027df82139db 212 Gene3D G3DSA:3.40.50.300 1 211 9.2E-52 T 11-10-2018 AFK25_14375 6fa2c0de931dabee855c027df82139db 212 SUPERFAMILY SSF52540 3 207 4.41E-50 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_14375 6fa2c0de931dabee855c027df82139db 212 Pfam PF00005 ABC transporter 20 159 4.2E-28 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_07810 1929aaa41cc39651659d307cb45a6962 208 SUPERFAMILY SSF53254 1 204 3.27E-59 T 11-10-2018 IPR029033 Histidine phosphatase superfamily AFK25_07810 1929aaa41cc39651659d307cb45a6962 208 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 4 194 5.2E-60 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFK25_07810 1929aaa41cc39651659d307cb45a6962 208 SMART SM00855 3 157 2.5E-21 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFK25_07810 1929aaa41cc39651659d307cb45a6962 208 Gene3D G3DSA:3.40.50.1240 2 205 3.4E-69 T 11-10-2018 IPR029033 Histidine phosphatase superfamily AFK25_07810 1929aaa41cc39651659d307cb45a6962 208 PIRSF PIRSF000709 2 171 1.6E-17 T 11-10-2018 AFK25_11285 d25033b7191d95ad4c96ab0fbb9ca435 480 Gene3D G3DSA:3.40.720.10 312 480 1.2E-37 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFK25_11285 d25033b7191d95ad4c96ab0fbb9ca435 480 SUPERFAMILY SSF53649 210 458 7.59E-52 T 11-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AFK25_11285 d25033b7191d95ad4c96ab0fbb9ca435 480 Pfam PF00884 Sulfatase 366 459 5.8E-16 T 11-10-2018 IPR000917 Sulfatase, N-terminal GO:0008484 AFK25_11285 d25033b7191d95ad4c96ab0fbb9ca435 480 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 216 282 5.0E-16 T 11-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 AFK25_11285 d25033b7191d95ad4c96ab0fbb9ca435 480 Gene3D G3DSA:3.40.720.10 207 309 1.9E-18 T 11-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AFK25_12030 ab3220d7849b83cc4539a02a40a0aa79 541 PIRSF PIRSF038958 1 537 1.9E-123 T 11-10-2018 IPR024923 Peptidoglycan biosynthesis protein, SpoVB-type AFK25_12030 ab3220d7849b83cc4539a02a40a0aa79 541 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 371 515 4.1E-30 T 11-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain AFK25_12030 ab3220d7849b83cc4539a02a40a0aa79 541 Pfam PF01943 Polysaccharide biosynthesis protein 6 318 4.4E-52 T 11-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 AFK25_14340 f71b3f1fbe84cdd1cec789ecf66fbcf2 239 ProDom PD835662 MEMBRANE PROTEIN YYBK 18 198 9.0E-23 T 11-10-2018 IPR024295 Protein of unknown function DUF2705 AFK25_14340 f71b3f1fbe84cdd1cec789ecf66fbcf2 239 Pfam PF10920 Protein of unknown function (DUF2705) 7 237 1.2E-33 T 11-10-2018 IPR024295 Protein of unknown function DUF2705 AFK25_12235 36200ccec5323a023bf8582a08d9750a 688 SUPERFAMILY SSF48208 485 581 7.37E-6 T 11-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AFK25_06925 c712cec15bf55081782171d068a2e7bf 49 Hamap MF_00665 Small, acid-soluble spore protein O [sspO]. 1 49 21.635 T 11-10-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 AFK25_06925 c712cec15bf55081782171d068a2e7bf 49 Pfam PF08175 Small acid-soluble spore protein O family 2 49 2.1E-26 T 11-10-2018 AFK25_06925 c712cec15bf55081782171d068a2e7bf 49 TIGRFAM TIGR02864 spore_sspO: small, acid-soluble spore protein O 1 49 4.8E-29 T 11-10-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 AFK25_06925 c712cec15bf55081782171d068a2e7bf 49 ProDom PD050103 O SPORE SMALL ACID-SOLUBLE SASP SPORULATION CAPSID COAT K SEQUENCING 3 37 3.0E-11 T 11-10-2018 IPR012613 Small acid-soluble spore protein, SspO GO:0030436|GO:0042601 AFK25_07170 03080276887ab8b6d8358ae4d9f8bd96 422 TIGRFAM TIGR02079 THD1: threonine dehydratase 15 422 1.2E-197 T 11-10-2018 IPR011820 L-threonine dehydratase biosynthetic IlvA GO:0004794 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 AFK25_07170 03080276887ab8b6d8358ae4d9f8bd96 422 Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase 329 421 1.3E-27 T 11-10-2018 IPR001721 Threonine dehydratase, ACT-like domain KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 AFK25_07170 03080276887ab8b6d8358ae4d9f8bd96 422 SUPERFAMILY SSF55021 339 415 6.87E-11 T 11-10-2018 AFK25_07170 03080276887ab8b6d8358ae4d9f8bd96 422 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 51 64 - T 11-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 AFK25_07170 03080276887ab8b6d8358ae4d9f8bd96 422 Gene3D G3DSA:3.40.1020.10 327 422 1.9E-10 T 11-10-2018 IPR038110 Threonine dehydratase, ACT-like domain superfamily KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 AFK25_07170 03080276887ab8b6d8358ae4d9f8bd96 422 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 26 316 3.4E-79 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFK25_07170 03080276887ab8b6d8358ae4d9f8bd96 422 Gene3D G3DSA:3.40.50.1100 24 326 1.6E-119 T 11-10-2018 AFK25_07170 03080276887ab8b6d8358ae4d9f8bd96 422 SUPERFAMILY SSF53686 12 365 1.15E-102 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFK25_07170 03080276887ab8b6d8358ae4d9f8bd96 422 Gene3D G3DSA:3.40.50.1100 59 158 1.6E-119 T 11-10-2018 AFK25_08335 163b118a635d62f3f99bda4a8898f767 299 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 3 62 7.3E-22 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFK25_08335 163b118a635d62f3f99bda4a8898f767 299 SUPERFAMILY SSF46785 1 84 5.77E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_08335 163b118a635d62f3f99bda4a8898f767 299 Pfam PF03466 LysR substrate binding domain 88 291 3.8E-46 T 11-10-2018 IPR005119 LysR, substrate-binding AFK25_08335 163b118a635d62f3f99bda4a8898f767 299 Gene3D G3DSA:1.10.10.10 1 84 9.9E-29 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_08335 163b118a635d62f3f99bda4a8898f767 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 39 50 2.7E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFK25_08335 163b118a635d62f3f99bda4a8898f767 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 18 29 2.7E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFK25_08335 163b118a635d62f3f99bda4a8898f767 299 PRINTS PR00039 LysR bacterial regulatory protein HTH signature 29 39 2.7E-10 T 11-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AFK25_08335 163b118a635d62f3f99bda4a8898f767 299 Gene3D G3DSA:3.40.190.290 90 296 1.9E-51 T 11-10-2018 AFK25_08335 163b118a635d62f3f99bda4a8898f767 299 SUPERFAMILY SSF53850 88 293 3.57E-41 T 11-10-2018 AFK25_05580 8d8e1a9ffc3ee3e31f20c4371abee31b 183 Gene3D G3DSA:2.10.109.10 58 182 4.0E-47 T 11-10-2018 AFK25_05580 8d8e1a9ffc3ee3e31f20c4371abee31b 183 TIGRFAM TIGR02227 sigpep_I_bact: signal peptidase I 11 176 1.2E-57 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AFK25_05580 8d8e1a9ffc3ee3e31f20c4371abee31b 183 ProSitePatterns PS00761 Signal peptidases I signature 3. 141 154 - T 11-10-2018 IPR019758 Peptidase S26A, signal peptidase I, conserved site GO:0008236|GO:0016021 AFK25_05580 8d8e1a9ffc3ee3e31f20c4371abee31b 183 ProSitePatterns PS00760 Signal peptidases I lysine active site. 80 92 - T 11-10-2018 IPR019757 Peptidase S26A, signal peptidase I, lysine active site GO:0008236|GO:0016021 AFK25_05580 8d8e1a9ffc3ee3e31f20c4371abee31b 183 Pfam PF00717 Peptidase S24-like 35 102 2.1E-22 T 11-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFK25_05580 8d8e1a9ffc3ee3e31f20c4371abee31b 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 136 155 1.4E-22 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AFK25_05580 8d8e1a9ffc3ee3e31f20c4371abee31b 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 28 44 1.4E-22 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AFK25_05580 8d8e1a9ffc3ee3e31f20c4371abee31b 183 PRINTS PR00727 Bacterial leader peptidase 1 (S26A) family signature 78 90 1.4E-22 T 11-10-2018 IPR000223 Peptidase S26A, signal peptidase I GO:0006508|GO:0008236|GO:0016020 AFK25_05580 8d8e1a9ffc3ee3e31f20c4371abee31b 183 ProSitePatterns PS00501 Signal peptidases I serine active site. 37 44 - T 11-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 AFK25_05580 8d8e1a9ffc3ee3e31f20c4371abee31b 183 SUPERFAMILY SSF51306 26 181 8.79E-57 T 11-10-2018 IPR036286 LexA/Signal peptidase-like superfamily AFK25_02305 996f7e20e0dd2d9bd62d753667838326 159 Gene3D G3DSA:1.10.4010.10 1 159 6.3E-17 T 11-10-2018 AFK25_02305 996f7e20e0dd2d9bd62d753667838326 159 SUPERFAMILY SSF101386 3 159 1.57E-39 T 11-10-2018 AFK25_02305 996f7e20e0dd2d9bd62d753667838326 159 PIRSF PIRSF030140 1 159 4.3E-50 T 11-10-2018 IPR016947 Uncharacterised phage-associated protein UCP030140 AFK25_02305 996f7e20e0dd2d9bd62d753667838326 159 Pfam PF08761 dUTPase 2 159 1.4E-44 T 11-10-2018 IPR014871 dUTPase/dCTP pyrophosphatase KEGG: 00240+3.6.1.12 AFK25_11175 0fe0c7b8666e9807aa78f49153efa267 514 Gene3D G3DSA:3.20.20.70 1 275 5.4E-116 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_11175 0fe0c7b8666e9807aa78f49153efa267 514 Hamap MF_01025 2-isopropylmalate synthase [leuA]. 1 509 43.915 T 11-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFK25_11175 0fe0c7b8666e9807aa78f49153efa267 514 Pfam PF00682 HMGL-like 3 272 2.4E-96 T 11-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AFK25_11175 0fe0c7b8666e9807aa78f49153efa267 514 SUPERFAMILY SSF51569 2 290 1.1E-98 T 11-10-2018 AFK25_11175 0fe0c7b8666e9807aa78f49153efa267 514 Gene3D G3DSA:1.10.238.260 279 392 2.1E-40 T 11-10-2018 AFK25_11175 0fe0c7b8666e9807aa78f49153efa267 514 Pfam PF08502 LeuA allosteric (dimerisation) domain 369 499 2.6E-38 T 11-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFK25_11175 0fe0c7b8666e9807aa78f49153efa267 514 TIGRFAM TIGR00973 leuA_bact: 2-isopropylmalate synthase 3 497 1.8E-233 T 11-10-2018 IPR005671 2-isopropylmalate synthase, bacterial-type GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFK25_11175 0fe0c7b8666e9807aa78f49153efa267 514 SUPERFAMILY SSF110921 395 499 4.32E-22 T 11-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFK25_11175 0fe0c7b8666e9807aa78f49153efa267 514 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 11 27 - T 11-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFK25_11175 0fe0c7b8666e9807aa78f49153efa267 514 Gene3D G3DSA:3.30.160.270 393 500 7.5E-13 T 11-10-2018 AFK25_11175 0fe0c7b8666e9807aa78f49153efa267 514 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 198 211 - T 11-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFK25_11175 0fe0c7b8666e9807aa78f49153efa267 514 SMART SM00917 368 500 3.7E-37 T 11-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AFK25_08030 a6b47f2d84f116c93fad4f26f655b539 413 Pfam PF07690 Major Facilitator Superfamily 271 410 9.9E-9 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFK25_08030 a6b47f2d84f116c93fad4f26f655b539 413 Pfam PF07690 Major Facilitator Superfamily 16 252 6.4E-32 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFK25_08030 a6b47f2d84f116c93fad4f26f655b539 413 ProSitePatterns PS00216 Sugar transport proteins signature 1. 62 79 - T 11-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFK25_08030 a6b47f2d84f116c93fad4f26f655b539 413 SUPERFAMILY SSF103473 5 409 1.06E-52 T 11-10-2018 IPR036259 MFS transporter superfamily AFK25_08030 a6b47f2d84f116c93fad4f26f655b539 413 Gene3D G3DSA:1.20.1250.20 8 404 3.7E-48 T 11-10-2018 AFK25_05340 440e02778c5cd412dc87c08395120771 308 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 1 293 39.745 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFK25_05340 440e02778c5cd412dc87c08395120771 308 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 147 287 5.5E-24 T 11-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 AFK25_05340 440e02778c5cd412dc87c08395120771 308 Gene3D G3DSA:3.40.50.1370 127 270 2.6E-101 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFK25_05340 440e02778c5cd412dc87c08395120771 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 207 216 1.3E-33 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFK25_05340 440e02778c5cd412dc87c08395120771 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 272 286 1.3E-33 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFK25_05340 440e02778c5cd412dc87c08395120771 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 71 80 1.3E-33 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFK25_05340 440e02778c5cd412dc87c08395120771 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 248 253 1.3E-33 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFK25_05340 440e02778c5cd412dc87c08395120771 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 33 55 1.3E-33 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFK25_05340 440e02778c5cd412dc87c08395120771 308 PRINTS PR00101 Aspartate carbamoyltransferase signature 126 143 1.3E-33 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFK25_05340 440e02778c5cd412dc87c08395120771 308 Gene3D G3DSA:3.40.50.1370 6 287 2.6E-101 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFK25_05340 440e02778c5cd412dc87c08395120771 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 244 253 6.4E-23 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFK25_05340 440e02778c5cd412dc87c08395120771 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 43 62 6.4E-23 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFK25_05340 440e02778c5cd412dc87c08395120771 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 256 279 6.4E-23 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFK25_05340 440e02778c5cd412dc87c08395120771 308 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 127 138 6.4E-23 T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFK25_05340 440e02778c5cd412dc87c08395120771 308 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 139 6.0E-40 T 11-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 AFK25_05340 440e02778c5cd412dc87c08395120771 308 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 43 50 - T 11-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AFK25_05340 440e02778c5cd412dc87c08395120771 308 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 2 291 2.7E-95 T 11-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AFK25_05340 440e02778c5cd412dc87c08395120771 308 SUPERFAMILY SSF53671 1 292 3.93E-93 T 11-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AFK25_09690 dc0c909c0dfcf6ecf6091d96f50b1904 203 Pfam PF04199 Putative cyclase 4 146 4.1E-25 T 11-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 AFK25_09690 dc0c909c0dfcf6ecf6091d96f50b1904 203 SUPERFAMILY SSF102198 1 201 4.58E-57 T 11-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 AFK25_09690 dc0c909c0dfcf6ecf6091d96f50b1904 203 Gene3D G3DSA:3.50.30.50 1 203 5.0E-79 T 11-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 AFK25_07350 18f0ee0721aee6e62b6659eb3fc46b1f 205 Pfam PF09335 SNARE associated Golgi protein 47 163 1.8E-31 T 11-10-2018 IPR032816 SNARE associated Golgi protein AFK25_05050 419fa1593674b10016dc19e4fb6ba3ad 396 Pfam PF13542 Helix-turn-helix domain of transposase family ISL3 85 132 7.0E-10 T 11-10-2018 IPR032877 Transposase IS204/IS1001/IS1096/IS1165, helix-turn-helix domain AFK25_05050 419fa1593674b10016dc19e4fb6ba3ad 396 Pfam PF14690 zinc-finger of transposase IS204/IS1001/IS1096/IS1165 34 78 3.6E-13 T 11-10-2018 IPR029261 Transposase IS204/IS1001/IS1096/IS1165, zinc-finger AFK25_05050 419fa1593674b10016dc19e4fb6ba3ad 396 Pfam PF01610 Transposase 155 382 3.8E-66 T 11-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain AFK25_09060 b47fcdc6d3d7ac9331835f78daac470c 326 Gene3D G3DSA:3.50.50.60 132 249 4.5E-56 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_09060 b47fcdc6d3d7ac9331835f78daac470c 326 TIGRFAM TIGR04018 Bthiol_YpdA: putative bacillithiol system oxidoreductase, YpdA family 6 319 3.8E-145 T 11-10-2018 IPR023856 Bacillithiol biosynthesis thiol disulphide oxidoreductase, YpdA AFK25_09060 b47fcdc6d3d7ac9331835f78daac470c 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 159 177 6.3E-12 T 11-10-2018 AFK25_09060 b47fcdc6d3d7ac9331835f78daac470c 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 6 25 6.3E-12 T 11-10-2018 AFK25_09060 b47fcdc6d3d7ac9331835f78daac470c 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 271 293 6.3E-12 T 11-10-2018 AFK25_09060 b47fcdc6d3d7ac9331835f78daac470c 326 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 242 258 6.3E-12 T 11-10-2018 AFK25_09060 b47fcdc6d3d7ac9331835f78daac470c 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 281 299 1.0E-17 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_09060 b47fcdc6d3d7ac9331835f78daac470c 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 212 228 1.0E-17 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_09060 b47fcdc6d3d7ac9331835f78daac470c 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 155 179 1.0E-17 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_09060 b47fcdc6d3d7ac9331835f78daac470c 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 5 27 1.0E-17 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_09060 b47fcdc6d3d7ac9331835f78daac470c 326 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 120 128 1.0E-17 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_09060 b47fcdc6d3d7ac9331835f78daac470c 326 Gene3D G3DSA:3.50.50.60 6 294 4.5E-56 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_09060 b47fcdc6d3d7ac9331835f78daac470c 326 SUPERFAMILY SSF51905 5 264 5.18E-39 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_09060 b47fcdc6d3d7ac9331835f78daac470c 326 Pfam PF13738 Pyridine nucleotide-disulphide oxidoreductase 7 290 6.3E-107 T 11-10-2018 AFK25_08975 673407dc047387c4078c02fab2afaa86 67 ProDom PD054986 YPHE TRANSMEMBRANE MEMBRANE PRECURSOR BH1643 SIGNAL 1 67 6.0E-16 T 11-10-2018 IPR020076 Protein of unknown function DUF2768 AFK25_08975 673407dc047387c4078c02fab2afaa86 67 Pfam PF10966 Protein of unknown function (DUF2768) 7 64 4.0E-26 T 11-10-2018 IPR020076 Protein of unknown function DUF2768 AFK25_09575 527ab2b8268eed46dc494c10c5b97cb0 390 Pfam PF07690 Major Facilitator Superfamily 22 351 5.0E-44 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFK25_09575 527ab2b8268eed46dc494c10c5b97cb0 390 SUPERFAMILY SSF103473 6 387 2.75E-64 T 11-10-2018 IPR036259 MFS transporter superfamily AFK25_09575 527ab2b8268eed46dc494c10c5b97cb0 390 Gene3D G3DSA:1.20.1250.20 9 387 6.5E-95 T 11-10-2018 AFK25_11420 bb02f641345272444c3b75e9063333d3 292 SUPERFAMILY SSF161098 52 279 8.76E-58 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_11420 bb02f641345272444c3b75e9063333d3 292 Gene3D G3DSA:1.10.3720.10 48 290 3.3E-66 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_11420 bb02f641345272444c3b75e9063333d3 292 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 281 1.3E-17 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_06865 204b0bfe177d0d1413fdb734bda29c72 205 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 159 171 9.1E-10 T 11-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AFK25_06865 204b0bfe177d0d1413fdb734bda29c72 205 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 130 141 9.1E-10 T 11-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AFK25_06865 204b0bfe177d0d1413fdb734bda29c72 205 PRINTS PR00726 Repressor LexA serine protease (S24) family signature 119 129 9.1E-10 T 11-10-2018 IPR006197 Peptidase S24, LexA-like GO:0003677|GO:0006355 AFK25_06865 204b0bfe177d0d1413fdb734bda29c72 205 TIGRFAM TIGR00498 lexA: repressor LexA 1 204 6.6E-83 T 11-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 AFK25_06865 204b0bfe177d0d1413fdb734bda29c72 205 Gene3D G3DSA:2.10.109.10 87 204 2.2E-44 T 11-10-2018 AFK25_06865 204b0bfe177d0d1413fdb734bda29c72 205 Pfam PF01726 LexA DNA binding domain 1 65 7.4E-29 T 11-10-2018 IPR006199 LexA repressor, DNA-binding domain GO:0004252|GO:0006508 AFK25_06865 204b0bfe177d0d1413fdb734bda29c72 205 SUPERFAMILY SSF46785 3 70 6.83E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_06865 204b0bfe177d0d1413fdb734bda29c72 205 Hamap MF_00015 LexA repressor [lexA]. 3 204 35.452 T 11-10-2018 IPR006200 Transcription regulator LexA GO:0004252|GO:0009432|GO:0045892 AFK25_06865 204b0bfe177d0d1413fdb734bda29c72 205 Gene3D G3DSA:1.10.10.10 2 68 9.9E-28 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_06865 204b0bfe177d0d1413fdb734bda29c72 205 Pfam PF00717 Peptidase S24-like 123 188 1.5E-18 T 11-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AFK25_06865 204b0bfe177d0d1413fdb734bda29c72 205 SUPERFAMILY SSF51306 81 202 1.96E-36 T 11-10-2018 IPR036286 LexA/Signal peptidase-like superfamily AFK25_03400 d417c1f355fce93918551c70c98dce26 59 Pfam PF14168 YjzC-like protein 1 55 1.4E-28 T 11-10-2018 IPR025549 YjzC-like protein AFK25_05585 43668beb02829156722af5d413efc2c3 281 SUPERFAMILY SSF52540 9 200 8.26E-49 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_05585 43668beb02829156722af5d413efc2c3 281 Gene3D G3DSA:1.10.1580.10 181 273 4.5E-31 T 11-10-2018 IPR023179 GTP-binding protein, orthogonal bundle domain superfamily AFK25_05585 43668beb02829156722af5d413efc2c3 281 Gene3D G3DSA:3.40.50.300 12 180 1.1E-47 T 11-10-2018 AFK25_05585 43668beb02829156722af5d413efc2c3 281 PIRSF PIRSF006230 1 281 2.8E-103 T 11-10-2018 IPR016478 GTPase, MTG1 AFK25_05585 43668beb02829156722af5d413efc2c3 281 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 124 144 1.2E-5 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_05585 43668beb02829156722af5d413efc2c3 281 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 170 185 1.2E-5 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_05585 43668beb02829156722af5d413efc2c3 281 TIGRFAM TIGR03596 GTPase_YlqF: ribosome biogenesis GTP-binding protein YlqF 3 279 8.5E-115 T 11-10-2018 IPR019991 GTP-binding protein, ribosome biogenesis AFK25_05585 43668beb02829156722af5d413efc2c3 281 Pfam PF01926 50S ribosome-binding GTPase 124 206 5.0E-18 T 11-10-2018 IPR006073 GTP binding domain GO:0005525 AFK25_07630 ba420677065c33eae36f2aa192f9615b 478 SUPERFAMILY SSF51905 4 475 5.95E-25 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_07630 ba420677065c33eae36f2aa192f9615b 478 Gene3D G3DSA:3.50.50.60 1 108 1.4E-15 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_07630 ba420677065c33eae36f2aa192f9615b 478 Gene3D G3DSA:3.50.50.60 125 257 6.3E-10 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_07630 ba420677065c33eae36f2aa192f9615b 478 PIRSF PIRSF038984 134 478 7.7E-22 T 11-10-2018 IPR028348 FAD dependent protein AFK25_07630 ba420677065c33eae36f2aa192f9615b 478 PIRSF PIRSF038984 1 104 4.3E-8 T 11-10-2018 IPR028348 FAD dependent protein AFK25_08040 a635862eb6b491103027ec225dcfc4be 299 Gene3D G3DSA:1.10.3470.10 7 270 5.2E-7 T 11-10-2018 IPR037294 ABC transporter, BtuC-like AFK25_08040 a635862eb6b491103027ec225dcfc4be 299 Pfam PF00950 ABC 3 transport family 3 266 2.6E-71 T 11-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 AFK25_08040 a635862eb6b491103027ec225dcfc4be 299 SUPERFAMILY SSF81345 10 263 2.62E-28 T 11-10-2018 IPR037294 ABC transporter, BtuC-like AFK25_06090 66ec00513f79113cf7031d61324d3f08 308 Gene3D G3DSA:3.40.91.100 138 300 9.9E-9 T 11-10-2018 AFK25_06090 66ec00513f79113cf7031d61324d3f08 308 Pfam PF04471 Restriction endonuclease 160 280 3.7E-36 T 11-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 AFK25_06090 66ec00513f79113cf7031d61324d3f08 308 SUPERFAMILY SSF52980 165 285 2.57E-15 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFK25_06090 66ec00513f79113cf7031d61324d3f08 308 Pfam PF14338 Mrr N-terminal domain 6 91 8.0E-35 T 11-10-2018 IPR025745 Restriction system protein Mrr-like N-terminal domain AFK25_06610 263069c268a46abb5a053a02c60b3b63 84 Pfam PF17334 Sigma-G-dependent sporulation-specific SASP protein 1 84 1.6E-33 T 11-10-2018 IPR020255 Sigma-G-dependent sporulation-specific SASP protein AFK25_06610 263069c268a46abb5a053a02c60b3b63 84 ProDom PD059965 SASP SPORULATION-SPECIFIC SIGMA-G-DEPENDENT SPORULATION SPECIFIC CSGA 1 84 1.0E-22 T 11-10-2018 IPR020255 Sigma-G-dependent sporulation-specific SASP protein AFK25_12220 254269e700e99e4d7b84105b0ba03738 163 Pfam PF00258 Flavodoxin 5 114 1.1E-17 T 11-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 AFK25_12220 254269e700e99e4d7b84105b0ba03738 163 Gene3D G3DSA:3.40.50.360 2 145 3.0E-26 T 11-10-2018 IPR029039 Flavoprotein-like superfamily AFK25_12220 254269e700e99e4d7b84105b0ba03738 163 SUPERFAMILY SSF52218 1 124 1.4E-25 T 11-10-2018 IPR029039 Flavoprotein-like superfamily AFK25_02795 6a4db0d0881007fc4142c66a0708a9cd 61 Pfam PF14120 YhzD-like protein 2 61 1.1E-32 T 11-10-2018 IPR025544 YhzD-like protein AFK25_11955 f4d55e5a37ba8fe58d32562113bfb669 279 SUPERFAMILY SSF56281 3 263 1.04E-41 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_11955 f4d55e5a37ba8fe58d32562113bfb669 279 Gene3D G3DSA:3.60.15.10 4 269 2.6E-84 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_11955 f4d55e5a37ba8fe58d32562113bfb669 279 Pfam PF00753 Metallo-beta-lactamase superfamily 54 221 2.1E-14 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_11955 f4d55e5a37ba8fe58d32562113bfb669 279 SMART SM00849 50 257 3.9E-15 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_00265 ba83b0b1c1150b4cabea3cd284d7e6d3 96 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 1 92 28.397 T 11-10-2018 IPR007170 Stage V sporulation protein G GO:0030435 AFK25_00265 ba83b0b1c1150b4cabea3cd284d7e6d3 96 SUPERFAMILY SSF160537 1 89 3.79E-34 T 11-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 AFK25_00265 ba83b0b1c1150b4cabea3cd284d7e6d3 96 Gene3D G3DSA:3.30.1120.40 1 96 4.3E-39 T 11-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 AFK25_00265 ba83b0b1c1150b4cabea3cd284d7e6d3 96 Pfam PF04026 SpoVG 1 81 3.1E-36 T 11-10-2018 IPR007170 Stage V sporulation protein G GO:0030435 AFK25_00315 f6d272c4fe2c97e3a52c844baec0250f 85 SMART SM00363 1 64 3.3E-10 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00315 f6d272c4fe2c97e3a52c844baec0250f 85 SUPERFAMILY SSF55174 1 77 2.49E-21 T 11-10-2018 AFK25_00315 f6d272c4fe2c97e3a52c844baec0250f 85 Pfam PF01479 S4 domain 1 47 2.6E-12 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00315 f6d272c4fe2c97e3a52c844baec0250f 85 PIRSF PIRSF038881 1 85 2.6E-34 T 11-10-2018 IPR025490 RNA-binding protein, HP1423 type AFK25_00315 f6d272c4fe2c97e3a52c844baec0250f 85 Gene3D G3DSA:3.10.290.10 1 85 1.0E-26 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFK25_02290 d14dc489a4953727cca77f2ecc426854 110 Pfam PF10782 Zinc-finger 5 52 2.0E-5 T 11-10-2018 IPR019718 Protein of unknown function DUF2602 AFK25_12805 70ac27b21ec3dd8a4acae60c597c62b8 390 SUPERFAMILY SSF53901 268 389 2.14E-44 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_12805 70ac27b21ec3dd8a4acae60c597c62b8 390 Gene3D G3DSA:3.40.47.10 131 386 1.5E-154 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_12805 70ac27b21ec3dd8a4acae60c597c62b8 390 PIRSF PIRSF000429 1 390 1.2E-136 T 11-10-2018 IPR002155 Thiolase GO:0016747 AFK25_12805 70ac27b21ec3dd8a4acae60c597c62b8 390 SUPERFAMILY SSF53901 2 264 1.53E-78 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_12805 70ac27b21ec3dd8a4acae60c597c62b8 390 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 388 3.2E-146 T 11-10-2018 IPR002155 Thiolase GO:0016747 AFK25_12805 70ac27b21ec3dd8a4acae60c597c62b8 390 ProSitePatterns PS00737 Thiolases signature 2. 336 352 - T 11-10-2018 IPR020613 Thiolase, conserved site GO:0016747 AFK25_12805 70ac27b21ec3dd8a4acae60c597c62b8 390 Gene3D G3DSA:3.40.47.10 5 273 1.5E-154 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_12805 70ac27b21ec3dd8a4acae60c597c62b8 390 Pfam PF02803 Thiolase, C-terminal domain 268 388 3.7E-49 T 11-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 AFK25_12805 70ac27b21ec3dd8a4acae60c597c62b8 390 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 86 104 - T 11-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 AFK25_12805 70ac27b21ec3dd8a4acae60c597c62b8 390 ProSitePatterns PS00099 Thiolases active site. 371 384 - T 11-10-2018 IPR020610 Thiolase, active site GO:0016747 AFK25_12805 70ac27b21ec3dd8a4acae60c597c62b8 390 Pfam PF00108 Thiolase, N-terminal domain 5 259 9.2E-80 T 11-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFK25_02195 b7f7043eb65136ab3a627ecdd64912cd 220 Gene3D G3DSA:3.50.40.10 67 204 4.5E-8 T 11-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 AFK25_02195 b7f7043eb65136ab3a627ecdd64912cd 220 Pfam PF03483 B3/4 domain 63 186 1.9E-17 T 11-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 AFK25_02195 b7f7043eb65136ab3a627ecdd64912cd 220 SUPERFAMILY SSF56037 49 217 4.18E-33 T 11-10-2018 AFK25_02195 b7f7043eb65136ab3a627ecdd64912cd 220 SMART SM00873 61 211 4.7E-9 T 11-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 AFK25_08980 fd28da31bf6585831d4be834ba382c6b 339 SUPERFAMILY SSF48179 179 330 5.95E-59 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFK25_08980 fd28da31bf6585831d4be834ba382c6b 339 ProSitePatterns PS00957 NAD-dependent glycerol-3-phosphate dehydrogenase signature. 187 208 - T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFK25_08980 fd28da31bf6585831d4be834ba382c6b 339 Gene3D G3DSA:1.10.1040.10 188 334 1.4E-54 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFK25_08980 fd28da31bf6585831d4be834ba382c6b 339 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 2 158 6.6E-60 T 11-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFK25_08980 fd28da31bf6585831d4be834ba382c6b 339 SUPERFAMILY SSF51735 2 177 5.34E-62 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_08980 fd28da31bf6585831d4be834ba382c6b 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 172 196 1.3E-48 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFK25_08980 fd28da31bf6585831d4be834ba382c6b 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 54 81 1.3E-48 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFK25_08980 fd28da31bf6585831d4be834ba382c6b 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 237 254 1.3E-48 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFK25_08980 fd28da31bf6585831d4be834ba382c6b 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 4 21 1.3E-48 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFK25_08980 fd28da31bf6585831d4be834ba382c6b 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 197 221 1.3E-48 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFK25_08980 fd28da31bf6585831d4be834ba382c6b 339 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 131 151 1.3E-48 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFK25_08980 fd28da31bf6585831d4be834ba382c6b 339 Gene3D G3DSA:3.40.50.720 1 186 1.0E-68 T 11-10-2018 AFK25_08980 fd28da31bf6585831d4be834ba382c6b 339 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 179 319 9.6E-56 T 11-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFK25_08980 fd28da31bf6585831d4be834ba382c6b 339 PIRSF PIRSF000114 1 331 1.4E-116 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFK25_08980 fd28da31bf6585831d4be834ba382c6b 339 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 1 321 39.759 T 11-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AFK25_14630 4b2ab53431fe96ae1aff811f0eab2ce3 282 SMART SM00470 27 117 2.9E-34 T 11-10-2018 IPR003115 ParB/Sulfiredoxin AFK25_14630 4b2ab53431fe96ae1aff811f0eab2ce3 282 SUPERFAMILY SSF110849 19 120 1.05E-28 T 11-10-2018 IPR036086 ParB/Sulfiredoxin superfamily AFK25_14630 4b2ab53431fe96ae1aff811f0eab2ce3 282 Gene3D G3DSA:3.90.1530.30 40 103 1.1E-25 T 11-10-2018 AFK25_14630 4b2ab53431fe96ae1aff811f0eab2ce3 282 Hamap MF_02015 Nucleoid occlusion protein [noc]. 3 279 37.311 T 11-10-2018 IPR023705 Nucleoid occlusion protein AFK25_14630 4b2ab53431fe96ae1aff811f0eab2ce3 282 TIGRFAM TIGR00180 parB_part: ParB/RepB/Spo0J family partition protein 24 203 3.0E-62 T 11-10-2018 IPR004437 ParB/RepB/Spo0J partition protein family GO:0003677 AFK25_14630 4b2ab53431fe96ae1aff811f0eab2ce3 282 Pfam PF02195 ParB-like nuclease domain 29 116 1.1E-27 T 11-10-2018 IPR003115 ParB/Sulfiredoxin AFK25_14630 4b2ab53431fe96ae1aff811f0eab2ce3 282 Gene3D G3DSA:1.10.10.2830 104 218 8.2E-37 T 11-10-2018 AFK25_14630 4b2ab53431fe96ae1aff811f0eab2ce3 282 SUPERFAMILY SSF109709 111 217 2.04E-34 T 11-10-2018 AFK25_14630 4b2ab53431fe96ae1aff811f0eab2ce3 282 TIGRFAM TIGR04285 nucleoid_noc: nucleoid occlusion protein 25 279 1.5E-113 T 11-10-2018 IPR023705 Nucleoid occlusion protein AFK25_05105 28c7e7ac0ca9c821bcfc1a6598e0f173 88 Pfam PF09902 Uncharacterized protein conserved in bacteria (DUF2129) 5 74 1.0E-32 T 11-10-2018 IPR016979 Protein of unknown function DUF2129 AFK25_05105 28c7e7ac0ca9c821bcfc1a6598e0f173 88 PIRSF PIRSF031653 1 87 3.2E-35 T 11-10-2018 IPR016979 Protein of unknown function DUF2129 AFK25_05105 28c7e7ac0ca9c821bcfc1a6598e0f173 88 Hamap MF_01126 UPF0298 protein . 1 78 22.723 T 11-10-2018 IPR016979 Protein of unknown function DUF2129 AFK25_08470 22c085c43df3097e7709dd03c42550c0 276 Gene3D G3DSA:3.20.20.100 1 276 3.3E-125 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFK25_08470 22c085c43df3097e7709dd03c42550c0 276 PRINTS PR00069 Aldo-keto reductase signature 39 63 4.8E-54 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFK25_08470 22c085c43df3097e7709dd03c42550c0 276 PRINTS PR00069 Aldo-keto reductase signature 125 142 4.8E-54 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFK25_08470 22c085c43df3097e7709dd03c42550c0 276 PRINTS PR00069 Aldo-keto reductase signature 197 221 4.8E-54 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFK25_08470 22c085c43df3097e7709dd03c42550c0 276 PRINTS PR00069 Aldo-keto reductase signature 95 113 4.8E-54 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFK25_08470 22c085c43df3097e7709dd03c42550c0 276 PRINTS PR00069 Aldo-keto reductase signature 159 188 4.8E-54 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFK25_08470 22c085c43df3097e7709dd03c42550c0 276 ProSitePatterns PS00062 Aldo/keto reductase family signature 2. 125 142 - T 11-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 AFK25_08470 22c085c43df3097e7709dd03c42550c0 276 PIRSF PIRSF000097 114 273 5.3E-55 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFK25_08470 22c085c43df3097e7709dd03c42550c0 276 PIRSF PIRSF000097 1 119 2.7E-41 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFK25_08470 22c085c43df3097e7709dd03c42550c0 276 Pfam PF00248 Aldo/keto reductase family 28 262 1.4E-53 T 11-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFK25_08470 22c085c43df3097e7709dd03c42550c0 276 SUPERFAMILY SSF51430 8 270 9.3E-99 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFK25_08470 22c085c43df3097e7709dd03c42550c0 276 ProSitePatterns PS00798 Aldo/keto reductase family signature 1. 43 60 - T 11-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 AFK25_08470 22c085c43df3097e7709dd03c42550c0 276 ProSitePatterns PS00063 Aldo/keto reductase family putative active site signature. 230 245 - T 11-10-2018 IPR018170 Aldo/keto reductase, conserved site GO:0016491|GO:0055114 AFK25_08595 082a468b9f7c12b76c1c2cdb80ef5dfd 226 Gene3D G3DSA:3.40.50.1820 1 221 3.5E-38 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold AFK25_08595 082a468b9f7c12b76c1c2cdb80ef5dfd 226 SUPERFAMILY SSF53474 3 220 1.74E-34 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold AFK25_08595 082a468b9f7c12b76c1c2cdb80ef5dfd 226 Pfam PF12697 Alpha/beta hydrolase family 6 213 2.5E-14 T 11-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AFK25_13770 6eced3cd2b7780696bb83cae7912ce47 76 Pfam PF06612 Protein of unknown function (DUF1146) 16 63 3.0E-21 T 11-10-2018 IPR009526 Protein of unknown function DUF1146 AFK25_13770 6eced3cd2b7780696bb83cae7912ce47 76 TIGRFAM TIGR02327 int_mem_ywzB: conserved hypothetical integral membrane protein 9 75 6.5E-23 T 11-10-2018 IPR009526 Protein of unknown function DUF1146 AFK25_08510 ed6f6c4372659f05f1a7014bc7c518bf 97 SUPERFAMILY SSF81301 10 97 8.65E-16 T 11-10-2018 AFK25_08510 ed6f6c4372659f05f1a7014bc7c518bf 97 Gene3D G3DSA:3.30.460.10 1 97 3.9E-19 T 11-10-2018 AFK25_08510 ed6f6c4372659f05f1a7014bc7c518bf 97 Pfam PF01909 Nucleotidyltransferase domain 13 80 4.7E-10 T 11-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFK25_14495 6555c53d1245dcb97475740b899bf28b 381 SUPERFAMILY SSF53335 227 374 6.31E-15 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_14495 6555c53d1245dcb97475740b899bf28b 381 Pfam PF01555 DNA methylase 239 333 2.6E-9 T 11-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 AFK25_14495 6555c53d1245dcb97475740b899bf28b 381 Pfam PF01555 DNA methylase 18 81 8.8E-12 T 11-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 AFK25_14495 6555c53d1245dcb97475740b899bf28b 381 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 53 67 5.6E-5 T 11-10-2018 AFK25_14495 6555c53d1245dcb97475740b899bf28b 381 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 239 251 5.6E-5 T 11-10-2018 AFK25_14495 6555c53d1245dcb97475740b899bf28b 381 Gene3D G3DSA:3.40.50.150 221 379 4.7E-19 T 11-10-2018 AFK25_14495 6555c53d1245dcb97475740b899bf28b 381 SUPERFAMILY SSF53335 25 271 3.98E-18 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_14495 6555c53d1245dcb97475740b899bf28b 381 ProSitePatterns PS00093 N-4 cytosine-specific DNA methylases signature. 243 248 - T 11-10-2018 IPR017985 DNA methylase, N-4 cytosine-specific, conserved site GO:0003677|GO:0015667|GO:0090124 AFK25_14495 6555c53d1245dcb97475740b899bf28b 381 Gene3D G3DSA:3.40.50.150 3 120 5.2E-17 T 11-10-2018 AFK25_14455 ae0faca720248c3c672822ed5a5369a7 171 Gene3D G3DSA:3.40.140.10 47 171 1.8E-45 T 11-10-2018 AFK25_14455 ae0faca720248c3c672822ed5a5369a7 171 Pfam PF04002 RadC-like JAB domain 50 169 1.1E-42 T 11-10-2018 IPR025657 RadC-like JAB domain AFK25_14515 c9454982a67050d98a522c5b7c0f3c5d 402 Gene3D G3DSA:2.40.10.10 180 301 6.2E-38 T 11-10-2018 AFK25_14515 c9454982a67050d98a522c5b7c0f3c5d 402 Gene3D G3DSA:2.40.10.10 68 179 4.8E-27 T 11-10-2018 AFK25_14515 c9454982a67050d98a522c5b7c0f3c5d 402 SMART SM00228 299 388 1.2E-8 T 11-10-2018 IPR001478 PDZ domain GO:0005515 AFK25_14515 c9454982a67050d98a522c5b7c0f3c5d 402 Pfam PF13180 PDZ domain 299 397 4.7E-18 T 11-10-2018 IPR001478 PDZ domain GO:0005515 AFK25_14515 c9454982a67050d98a522c5b7c0f3c5d 402 Pfam PF13365 Trypsin-like peptidase domain 114 261 1.8E-31 T 11-10-2018 AFK25_14515 c9454982a67050d98a522c5b7c0f3c5d 402 SUPERFAMILY SSF50156 298 398 3.94E-20 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 AFK25_14515 c9454982a67050d98a522c5b7c0f3c5d 402 SUPERFAMILY SSF50494 79 296 2.94E-58 T 11-10-2018 IPR009003 Peptidase S1, PA clan AFK25_14515 c9454982a67050d98a522c5b7c0f3c5d 402 Gene3D G3DSA:2.30.42.10 302 401 4.8E-24 T 11-10-2018 AFK25_14515 c9454982a67050d98a522c5b7c0f3c5d 402 PRINTS PR00834 HtrA/DegQ protease family signature 254 271 2.4E-36 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFK25_14515 c9454982a67050d98a522c5b7c0f3c5d 402 PRINTS PR00834 HtrA/DegQ protease family signature 147 167 2.4E-36 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFK25_14515 c9454982a67050d98a522c5b7c0f3c5d 402 PRINTS PR00834 HtrA/DegQ protease family signature 232 249 2.4E-36 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFK25_14515 c9454982a67050d98a522c5b7c0f3c5d 402 PRINTS PR00834 HtrA/DegQ protease family signature 126 138 2.4E-36 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFK25_14515 c9454982a67050d98a522c5b7c0f3c5d 402 PRINTS PR00834 HtrA/DegQ protease family signature 188 212 2.4E-36 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFK25_14515 c9454982a67050d98a522c5b7c0f3c5d 402 PRINTS PR00834 HtrA/DegQ protease family signature 345 357 2.4E-36 T 11-10-2018 IPR001940 Peptidase S1C GO:0004252|GO:0006508 AFK25_02115 3bcf5ef95dd358084103deefcdde871d 156 Pfam PF00583 Acetyltransferase (GNAT) family 43 145 1.3E-16 T 11-10-2018 IPR000182 GNAT domain AFK25_02115 3bcf5ef95dd358084103deefcdde871d 156 Gene3D G3DSA:3.40.630.30 5 156 6.6E-41 T 11-10-2018 AFK25_02115 3bcf5ef95dd358084103deefcdde871d 156 SUPERFAMILY SSF55729 5 149 3.55E-28 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFK25_08255 ca4b96a46402283a8fa9e8d8762bbc5e 95 SUPERFAMILY SSF54862 25 93 2.77E-15 T 11-10-2018 AFK25_08255 ca4b96a46402283a8fa9e8d8762bbc5e 95 Pfam PF05187 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S 16 90 1.0E-10 T 11-10-2018 AFK25_08255 ca4b96a46402283a8fa9e8d8762bbc5e 95 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 64 75 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFK25_08255 ca4b96a46402283a8fa9e8d8762bbc5e 95 PIRSF PIRSF036548 1 95 1.5E-22 T 11-10-2018 IPR012206 Ferredoxin-like, FixX GO:0005506 AFK25_08255 ca4b96a46402283a8fa9e8d8762bbc5e 95 Gene3D G3DSA:3.30.70.20 11 89 9.6E-17 T 11-10-2018 AFK25_10635 2d0cdcf5e261756d5c9f8deae3e0d49c 582 Gene3D G3DSA:3.90.1310.30 47 230 2.2E-11 T 11-10-2018 AFK25_10635 2d0cdcf5e261756d5c9f8deae3e0d49c 582 SUPERFAMILY SSF56601 185 574 7.09E-57 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFK25_10635 2d0cdcf5e261756d5c9f8deae3e0d49c 582 SUPERFAMILY SSF56519 47 221 4.32E-18 T 11-10-2018 IPR036138 Penicillin-binding protein, dimerisation domain superfamily GO:0008658 AFK25_10635 2d0cdcf5e261756d5c9f8deae3e0d49c 582 Gene3D G3DSA:3.40.710.10 234 581 2.9E-69 T 11-10-2018 AFK25_10635 2d0cdcf5e261756d5c9f8deae3e0d49c 582 Pfam PF03717 Penicillin-binding Protein dimerisation domain 111 216 2.3E-6 T 11-10-2018 IPR005311 Penicillin-binding protein, dimerisation domain GO:0008658 AFK25_10635 2d0cdcf5e261756d5c9f8deae3e0d49c 582 Pfam PF00905 Penicillin binding protein transpeptidase domain 260 568 6.8E-48 T 11-10-2018 IPR001460 Penicillin-binding protein, transpeptidase GO:0008658 AFK25_11350 1582aae8ce6988f60d896b8a9aa5b595 179 Pfam PF02674 Colicin V production protein 2 164 9.7E-37 T 11-10-2018 IPR003825 Colicin V production, CvpA GO:0009403|GO:0016020 AFK25_06295 4d74071b9a4103e30416d6dde8e182df 506 Gene3D G3DSA:3.40.309.10 266 464 1.7E-166 T 11-10-2018 IPR016163 Aldehyde dehydrogenase, C-terminal GO:0016491|GO:0016620|GO:0055114 AFK25_06295 4d74071b9a4103e30416d6dde8e182df 506 ProSitePatterns PS00070 Aldehyde dehydrogenases cysteine active site. 294 305 - T 11-10-2018 IPR016160 Aldehyde dehydrogenase, cysteine active site GO:0016491|GO:0055114 AFK25_06295 4d74071b9a4103e30416d6dde8e182df 506 SUPERFAMILY SSF53720 12 498 2.36E-166 T 11-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AFK25_06295 4d74071b9a4103e30416d6dde8e182df 506 ProSitePatterns PS00687 Aldehyde dehydrogenases glutamic acid active site. 261 268 - T 11-10-2018 IPR029510 Aldehyde dehydrogenase, glutamic acid active site GO:0016491|GO:0055114 AFK25_06295 4d74071b9a4103e30416d6dde8e182df 506 Gene3D G3DSA:3.40.605.10 23 492 1.7E-166 T 11-10-2018 IPR016162 Aldehyde dehydrogenase, N-terminal GO:0016491|GO:0055114 AFK25_06295 4d74071b9a4103e30416d6dde8e182df 506 Pfam PF00171 Aldehyde dehydrogenase family 27 493 2.3E-169 T 11-10-2018 IPR015590 Aldehyde dehydrogenase domain GO:0016491|GO:0055114 AFK25_04430 50b122b3a7825c9fef215d1f9de25d5a 472 Gene3D G3DSA:3.30.565.10 318 470 1.7E-41 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_04430 50b122b3a7825c9fef215d1f9de25d5a 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 432 450 7.7E-14 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04430 50b122b3a7825c9fef215d1f9de25d5a 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 456 469 7.7E-14 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04430 50b122b3a7825c9fef215d1f9de25d5a 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 417 7.7E-14 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04430 50b122b3a7825c9fef215d1f9de25d5a 472 PRINTS PR00344 Bacterial sensor protein C-terminal signature 421 431 7.7E-14 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_04430 50b122b3a7825c9fef215d1f9de25d5a 472 SUPERFAMILY SSF47384 245 324 1.18E-14 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFK25_04430 50b122b3a7825c9fef215d1f9de25d5a 472 Pfam PF00512 His Kinase A (phospho-acceptor) domain 261 322 2.8E-15 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_04430 50b122b3a7825c9fef215d1f9de25d5a 472 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 368 470 2.3E-24 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_04430 50b122b3a7825c9fef215d1f9de25d5a 472 SUPERFAMILY SSF55874 320 470 1.19E-39 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_04430 50b122b3a7825c9fef215d1f9de25d5a 472 SMART SM00388 259 324 1.0E-15 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_04430 50b122b3a7825c9fef215d1f9de25d5a 472 Gene3D G3DSA:1.10.287.130 262 317 8.4E-17 T 11-10-2018 AFK25_04430 50b122b3a7825c9fef215d1f9de25d5a 472 Gene3D G3DSA:3.30.450.20 119 205 7.6E-7 T 11-10-2018 AFK25_04430 50b122b3a7825c9fef215d1f9de25d5a 472 SMART SM00387 366 472 8.5E-33 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_02640 4daa56774ec0b971ab096400d6e920f9 310 Gene3D G3DSA:3.30.479.30 69 208 6.2E-22 T 11-10-2018 AFK25_02640 4daa56774ec0b971ab096400d6e920f9 310 Pfam PF01145 SPFH domain / Band 7 family 44 223 5.5E-27 T 11-10-2018 IPR001107 Band 7 domain AFK25_02640 4daa56774ec0b971ab096400d6e920f9 310 PIRSF PIRSF005651 17 310 1.4E-95 T 11-10-2018 IPR010200 HflC GO:0016021|GO:0052547 AFK25_02640 4daa56774ec0b971ab096400d6e920f9 310 SUPERFAMILY SSF117892 72 212 3.14E-23 T 11-10-2018 IPR036013 Band 7/SPFH domain superfamily AFK25_02640 4daa56774ec0b971ab096400d6e920f9 310 SMART SM00244 40 207 2.0E-19 T 11-10-2018 IPR001107 Band 7 domain AFK25_08125 cbeaa4c3a6b9ef74e30bbb74d32420bb 409 Pfam PF12698 ABC-2 family transporter protein 20 380 4.4E-53 T 11-10-2018 AFK25_06630 6ab5c6b20106c2a54a7b8ef38530c0e4 561 SUPERFAMILY SSF48371 5 258 8.13E-5 T 11-10-2018 IPR016024 Armadillo-type fold AFK25_05480 13de367ad9f417c89a0150eff9d97eca 552 SUPERFAMILY SSF101473 3 202 6.15E-48 T 11-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFK25_05480 13de367ad9f417c89a0150eff9d97eca 552 SMART SM01120 36 201 1.6E-73 T 11-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFK25_05480 13de367ad9f417c89a0150eff9d97eca 552 Gene3D G3DSA:1.25.40.340 5 180 1.9E-12 T 11-10-2018 IPR036117 DhaL domain superfamily GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFK25_05480 13de367ad9f417c89a0150eff9d97eca 552 SMART SM01121 238 552 9.2E-187 T 11-10-2018 IPR033470 Uncharacterised protein, DhaK domain AFK25_05480 13de367ad9f417c89a0150eff9d97eca 552 Pfam PF02734 DAK2 domain 36 200 4.1E-43 T 11-10-2018 IPR004007 DhaL domain GO:0004371|GO:0006071 Reactome: R-HSA-168928|Reactome: R-HSA-70350 AFK25_05480 13de367ad9f417c89a0150eff9d97eca 552 TIGRFAM TIGR03599 YloV: DAK2 domain fusion protein YloV 11 552 1.2E-218 T 11-10-2018 IPR019986 DAK2 domain-containing protein YloV AFK25_05480 13de367ad9f417c89a0150eff9d97eca 552 Pfam PF13684 Dihydroxyacetone kinase family 238 552 4.0E-127 T 11-10-2018 IPR033470 Uncharacterised protein, DhaK domain AFK25_06835 624ebfbb091ea3a6277ed054a3f0d16a 384 Pfam PF00108 Thiolase, N-terminal domain 4 251 2.6E-79 T 11-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AFK25_06835 624ebfbb091ea3a6277ed054a3f0d16a 384 ProSitePatterns PS00737 Thiolases signature 2. 328 344 - T 11-10-2018 IPR020613 Thiolase, conserved site GO:0016747 AFK25_06835 624ebfbb091ea3a6277ed054a3f0d16a 384 Gene3D G3DSA:3.40.47.10 6 265 8.8E-152 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_06835 624ebfbb091ea3a6277ed054a3f0d16a 384 Gene3D G3DSA:3.40.47.10 127 379 8.8E-152 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_06835 624ebfbb091ea3a6277ed054a3f0d16a 384 ProSitePatterns PS00099 Thiolases active site. 363 376 - T 11-10-2018 IPR020610 Thiolase, active site GO:0016747 AFK25_06835 624ebfbb091ea3a6277ed054a3f0d16a 384 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 380 1.5E-141 T 11-10-2018 IPR002155 Thiolase GO:0016747 AFK25_06835 624ebfbb091ea3a6277ed054a3f0d16a 384 SUPERFAMILY SSF53901 260 381 1.48E-42 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_06835 624ebfbb091ea3a6277ed054a3f0d16a 384 SUPERFAMILY SSF53901 1 253 1.24E-78 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_06835 624ebfbb091ea3a6277ed054a3f0d16a 384 Pfam PF02803 Thiolase, C-terminal domain 259 381 2.5E-44 T 11-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 AFK25_06835 624ebfbb091ea3a6277ed054a3f0d16a 384 PIRSF PIRSF000429 1 383 3.8E-134 T 11-10-2018 IPR002155 Thiolase GO:0016747 AFK25_10955 10827dbad4453a0fb74175a65f574a62 174 Pfam PF04093 rod shape-determining protein MreD 3 161 4.8E-26 T 11-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 AFK25_10955 10827dbad4453a0fb74175a65f574a62 174 TIGRFAM TIGR03426 shape_MreD: rod shape-determining protein MreD 7 158 1.5E-23 T 11-10-2018 IPR007227 Cell shape-determining protein MreD GO:0008360|GO:0016021 AFK25_03200 67a97df6ffe7ed65e0760a4de681bb40 504 Gene3D G3DSA:3.20.20.80 26 388 1.6E-173 T 11-10-2018 AFK25_03200 67a97df6ffe7ed65e0760a4de681bb40 504 SMART SM00642 36 384 1.5E-112 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFK25_03200 67a97df6ffe7ed65e0760a4de681bb40 504 PIRSF PIRSF001024 1 471 4.2E-92 T 11-10-2018 IPR013777 Alpha-amylase-like GO:0004556|GO:0005509|GO:0005975 AFK25_03200 67a97df6ffe7ed65e0760a4de681bb40 504 SUPERFAMILY SSF51011 393 471 5.04E-11 T 11-10-2018 AFK25_03200 67a97df6ffe7ed65e0760a4de681bb40 504 Pfam PF00128 Alpha amylase, catalytic domain 64 359 1.5E-79 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFK25_03200 67a97df6ffe7ed65e0760a4de681bb40 504 SUPERFAMILY SSF51445 25 393 2.17E-111 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily AFK25_03200 67a97df6ffe7ed65e0760a4de681bb40 504 Gene3D G3DSA:2.60.40.1180 389 483 1.3E-39 T 11-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFK25_07010 c4a2e252a9a1cabab716bb326f3957bd 307 Gene3D G3DSA:3.40.1190.20 1 306 1.7E-108 T 11-10-2018 IPR029056 Ribokinase-like AFK25_07010 c4a2e252a9a1cabab716bb326f3957bd 307 PIRSF PIRSF000535 1 303 2.1E-89 T 11-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 AFK25_07010 c4a2e252a9a1cabab716bb326f3957bd 307 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 243 256 - T 11-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AFK25_07010 c4a2e252a9a1cabab716bb326f3957bd 307 SUPERFAMILY SSF53613 1 302 4.05E-68 T 11-10-2018 IPR029056 Ribokinase-like AFK25_07010 c4a2e252a9a1cabab716bb326f3957bd 307 Pfam PF00294 pfkB family carbohydrate kinase 10 282 2.3E-52 T 11-10-2018 IPR011611 Carbohydrate kinase PfkB AFK25_07010 c4a2e252a9a1cabab716bb326f3957bd 307 TIGRFAM TIGR03828 pfkB: 1-phosphofructokinase 2 300 3.5E-110 T 11-10-2018 IPR022463 Fructose 1-phosphate kinase GO:0008662 KEGG: 00051+2.7.1.56 AFK25_07010 c4a2e252a9a1cabab716bb326f3957bd 307 TIGRFAM TIGR03168 1-PFK: hexose kinase, 1-phosphofructokinase family 2 300 3.9E-110 T 11-10-2018 IPR017583 Tagatose/fructose phosphokinase GO:0005975|GO:0016773 AFK25_14520 e5b09e10d20b90250de14399046caa2e 262 SMART SM00849 11 216 1.3E-13 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_14520 e5b09e10d20b90250de14399046caa2e 262 SUPERFAMILY SSF56281 1 245 1.57E-45 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_14520 e5b09e10d20b90250de14399046caa2e 262 Gene3D G3DSA:3.60.15.10 6 247 1.9E-43 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_14520 e5b09e10d20b90250de14399046caa2e 262 Pfam PF00753 Metallo-beta-lactamase superfamily 10 216 1.1E-24 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_01410 78cefcf9b7540b2a6f652064f49e7425 485 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 11 477 99.174 T 11-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFK25_01410 78cefcf9b7540b2a6f652064f49e7425 485 Gene3D G3DSA:3.90.1300.10 2 485 1.6E-208 T 11-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFK25_01410 78cefcf9b7540b2a6f652064f49e7425 485 Pfam PF01425 Amidase 24 465 1.7E-170 T 11-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFK25_01410 78cefcf9b7540b2a6f652064f49e7425 485 SUPERFAMILY SSF75304 1 483 1.57E-176 T 11-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFK25_01410 78cefcf9b7540b2a6f652064f49e7425 485 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 12 477 1.9E-212 T 11-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AFK25_01410 78cefcf9b7540b2a6f652064f49e7425 485 ProSitePatterns PS00571 Amidases signature. 152 183 - T 11-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 AFK25_14445 a12bd585f30d1c43cbff7a024c477be0 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 130 146 9.5E-61 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFK25_14445 a12bd585f30d1c43cbff7a024c477be0 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 56 77 9.5E-61 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFK25_14445 a12bd585f30d1c43cbff7a024c477be0 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 40 56 9.5E-61 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFK25_14445 a12bd585f30d1c43cbff7a024c477be0 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 99 112 9.5E-61 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFK25_14445 a12bd585f30d1c43cbff7a024c477be0 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 300 326 9.5E-61 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFK25_14445 a12bd585f30d1c43cbff7a024c477be0 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 83 97 9.5E-61 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFK25_14445 a12bd585f30d1c43cbff7a024c477be0 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 211 230 9.5E-61 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFK25_14445 a12bd585f30d1c43cbff7a024c477be0 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 156 170 9.5E-61 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFK25_14445 a12bd585f30d1c43cbff7a024c477be0 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 174 193 9.5E-61 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFK25_14445 a12bd585f30d1c43cbff7a024c477be0 357 PRINTS PR00909 Bacterial periplasmic spermidine/putrescine-binding protein signature 255 274 9.5E-61 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFK25_14445 a12bd585f30d1c43cbff7a024c477be0 357 Gene3D G3DSA:3.40.190.10 39 322 8.9E-124 T 11-10-2018 AFK25_14445 a12bd585f30d1c43cbff7a024c477be0 357 PIRSF PIRSF019574 1 356 6.6E-135 T 11-10-2018 IPR001188 Bacterial periplasmic spermidine/putrescine-binding protein GO:0015846|GO:0019808|GO:0042597 AFK25_14445 a12bd585f30d1c43cbff7a024c477be0 357 Pfam PF13416 Bacterial extracellular solute-binding protein 49 320 4.8E-42 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFK25_14445 a12bd585f30d1c43cbff7a024c477be0 357 Gene3D G3DSA:3.40.190.10 139 329 8.9E-124 T 11-10-2018 AFK25_14445 a12bd585f30d1c43cbff7a024c477be0 357 SUPERFAMILY SSF53850 34 353 4.98E-100 T 11-10-2018 AFK25_10935 9de0dbcce3b6d9449749821d093c89af 287 Pfam PF02163 Peptidase family M50 106 168 1.1E-6 T 11-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 AFK25_02225 bd9db540ec3db1a124cf0257f02d180c 517 SUPERFAMILY SSF53041 9 166 1.83E-24 T 11-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 AFK25_02225 bd9db540ec3db1a124cf0257f02d180c 517 Gene3D G3DSA:3.40.50.1390 6 149 1.6E-21 T 11-10-2018 AFK25_02225 bd9db540ec3db1a124cf0257f02d180c 517 SMART SM00857 9 167 4.1E-31 T 11-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFK25_02225 bd9db540ec3db1a124cf0257f02d180c 517 Gene3D G3DSA:1.10.10.2600 151 297 5.1E-19 T 11-10-2018 IPR038109 DNA-binding recombinase domain superfamily AFK25_02225 bd9db540ec3db1a124cf0257f02d180c 517 Pfam PF07508 Recombinase 189 293 4.6E-24 T 11-10-2018 IPR011109 DNA-binding recombinase domain GO:0000150|GO:0003677 AFK25_02225 bd9db540ec3db1a124cf0257f02d180c 517 Pfam PF00239 Resolvase, N terminal domain 10 166 5.4E-23 T 11-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFK25_14210 a64723cc747b14644e5f7f86cd7f91dd 221 Gene3D G3DSA:3.20.20.70 1 219 2.2E-103 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_14210 a64723cc747b14644e5f7f86cd7f91dd 221 TIGRFAM TIGR00126 deoC: deoxyribose-phosphate aldolase 3 212 1.8E-93 T 11-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFK25_14210 a64723cc747b14644e5f7f86cd7f91dd 221 SMART SM01133 2 214 2.1E-112 T 11-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFK25_14210 a64723cc747b14644e5f7f86cd7f91dd 221 SUPERFAMILY SSF51569 1 215 5.65E-89 T 11-10-2018 AFK25_14210 a64723cc747b14644e5f7f86cd7f91dd 221 Pfam PF01791 DeoC/LacD family aldolase 7 211 3.8E-20 T 11-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFK25_14210 a64723cc747b14644e5f7f86cd7f91dd 221 Hamap MF_00114 Deoxyribose-phosphate aldolase [deoC]. 1 216 39.29 T 11-10-2018 IPR028581 Deoxyribose-phosphate aldolase type I GO:0004139 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180 AFK25_14210 a64723cc747b14644e5f7f86cd7f91dd 221 PIRSF PIRSF001357 1 220 7.4E-83 T 11-10-2018 IPR011343 Deoxyribose-phosphate aldolase GO:0004139|GO:0005737|GO:0009264 KEGG: 00030+4.1.2.4|MetaCyc: PWY-7180|Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AFK25_01620 1f7b3f4233a51dabe2449e79730edea6 266 Pfam PF01061 ABC-2 type transporter 20 229 1.3E-32 T 11-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AFK25_01620 1f7b3f4233a51dabe2449e79730edea6 266 PIRSF PIRSF006648 2 266 7.9E-78 T 11-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFK25_01620 1f7b3f4233a51dabe2449e79730edea6 266 PRINTS PR00164 ABC-2 type transport system membrane protein signature 189 208 4.5E-6 T 11-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFK25_01620 1f7b3f4233a51dabe2449e79730edea6 266 PRINTS PR00164 ABC-2 type transport system membrane protein signature 209 228 4.5E-6 T 11-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFK25_01620 1f7b3f4233a51dabe2449e79730edea6 266 PRINTS PR00164 ABC-2 type transport system membrane protein signature 116 141 4.5E-6 T 11-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AFK25_01235 631fc2fb5f481821631848b0a9148ce7 245 Pfam PF02517 CAAX protease self-immunity 129 213 2.8E-16 T 11-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 AFK25_07770 beaeae79cbe6d73bafcff0802f322f2d 253 Gene3D G3DSA:1.10.12.10 196 253 2.1E-18 T 11-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AFK25_07770 beaeae79cbe6d73bafcff0802f322f2d 253 Gene3D G3DSA:3.90.226.10 1 195 1.5E-57 T 11-10-2018 AFK25_07770 beaeae79cbe6d73bafcff0802f322f2d 253 Pfam PF00378 Enoyl-CoA hydratase/isomerase 9 252 7.3E-56 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFK25_07770 beaeae79cbe6d73bafcff0802f322f2d 253 SUPERFAMILY SSF52096 1 253 6.59E-71 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFK25_09335 e860fd75039ef2a2310d75784502305c 154 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 13 150 1.4E-60 T 11-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFK25_09335 e860fd75039ef2a2310d75784502305c 154 Gene3D G3DSA:3.40.50.960 1 154 1.1E-67 T 11-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFK25_09335 e860fd75039ef2a2310d75784502305c 154 SUPERFAMILY SSF52121 3 153 2.22E-64 T 11-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFK25_09335 e860fd75039ef2a2310d75784502305c 154 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 8 153 31.81 T 11-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFK25_09335 e860fd75039ef2a2310d75784502305c 154 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 12 151 6.5E-62 T 11-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AFK25_05845 266f1ba8b529dc5bdd4f01eaae738219 255 ProSitePatterns PS01315 Phosphatidate cytidylyltransferase signature. 213 239 - T 11-10-2018 IPR000374 Phosphatidate cytidylyltransferase GO:0016020|GO:0016772 KEGG: 00564+2.7.7.41|KEGG: 04070+2.7.7.41|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7817 AFK25_05845 266f1ba8b529dc5bdd4f01eaae738219 255 Pfam PF01148 Cytidylyltransferase family 2 253 8.9E-69 T 11-10-2018 AFK25_03320 06621087447c0b2e0b0d1041821c5d1e 163 Gene3D G3DSA:3.30.70.860 6 163 2.3E-62 T 11-10-2018 IPR035571 UPF0234-like, C-terminal AFK25_03320 06621087447c0b2e0b0d1041821c5d1e 163 Hamap MF_00632 UPF0234 protein YajQ [yajQ]. 4 163 26.461 T 11-10-2018 IPR007551 Protein of unknown function DUF520 AFK25_03320 06621087447c0b2e0b0d1041821c5d1e 163 SUPERFAMILY SSF89963 6 90 8.63E-30 T 11-10-2018 IPR036183 YajQ-like superfamily AFK25_03320 06621087447c0b2e0b0d1041821c5d1e 163 SUPERFAMILY SSF89963 92 163 8.37E-26 T 11-10-2018 IPR036183 YajQ-like superfamily AFK25_03320 06621087447c0b2e0b0d1041821c5d1e 163 Gene3D G3DSA:3.30.70.990 12 101 2.3E-62 T 11-10-2018 IPR035570 UPF0234, N-terminal AFK25_03320 06621087447c0b2e0b0d1041821c5d1e 163 Pfam PF04461 Protein of unknown function (DUF520) 5 163 4.6E-62 T 11-10-2018 IPR007551 Protein of unknown function DUF520 AFK25_00550 0455e1315a80c746f80e80385d7997e1 166 Gene3D G3DSA:3.30.70.1730 2 165 9.2E-46 T 11-10-2018 AFK25_00550 0455e1315a80c746f80e80385d7997e1 166 Hamap MF_00362 50S ribosomal protein L10 [rplJ]. 3 161 30.081 T 11-10-2018 IPR022973 Ribosomal protein L10 AFK25_00550 0455e1315a80c746f80e80385d7997e1 166 Pfam PF00466 Ribosomal protein L10 6 101 5.4E-33 T 11-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 AFK25_00550 0455e1315a80c746f80e80385d7997e1 166 ProSitePatterns PS01109 Ribosomal protein L10 signature. 8 42 - T 11-10-2018 IPR002363 Ribosomal protein L10, eubacterial, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_00550 0455e1315a80c746f80e80385d7997e1 166 SUPERFAMILY SSF160369 5 160 1.83E-57 T 11-10-2018 AFK25_12825 9176e1eb366bb8443af6f1aad8f5c5f2 107 Pfam PF07875 Coat F domain 17 78 6.4E-25 T 11-10-2018 IPR012851 Spore coat protein CotF-like AFK25_06990 66d4f1f1c7c3e19d57c2aabacbbf9ff3 494 Hamap MF_00186 Glycerol kinase [glpK]. 1 494 59.854 T 11-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 AFK25_06990 66d4f1f1c7c3e19d57c2aabacbbf9ff3 494 Gene3D G3DSA:3.30.420.40 1 250 1.9E-113 T 11-10-2018 AFK25_06990 66d4f1f1c7c3e19d57c2aabacbbf9ff3 494 ProSitePatterns PS00933 FGGY family of carbohydrate kinases signature 1. 132 144 - T 11-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFK25_06990 66d4f1f1c7c3e19d57c2aabacbbf9ff3 494 SUPERFAMILY SSF53067 252 490 2.81E-86 T 11-10-2018 AFK25_06990 66d4f1f1c7c3e19d57c2aabacbbf9ff3 494 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 2 249 1.1E-91 T 11-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 AFK25_06990 66d4f1f1c7c3e19d57c2aabacbbf9ff3 494 PIRSF PIRSF000538 1 494 1.8E-185 T 11-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFK25_06990 66d4f1f1c7c3e19d57c2aabacbbf9ff3 494 Gene3D G3DSA:3.30.420.40 251 494 6.1E-92 T 11-10-2018 AFK25_06990 66d4f1f1c7c3e19d57c2aabacbbf9ff3 494 SUPERFAMILY SSF53067 2 252 7.95E-100 T 11-10-2018 AFK25_06990 66d4f1f1c7c3e19d57c2aabacbbf9ff3 494 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 359 379 - T 11-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AFK25_06990 66d4f1f1c7c3e19d57c2aabacbbf9ff3 494 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 258 447 6.7E-65 T 11-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 AFK25_06990 66d4f1f1c7c3e19d57c2aabacbbf9ff3 494 TIGRFAM TIGR01311 glycerol_kin: glycerol kinase 2 491 2.1E-230 T 11-10-2018 IPR005999 Glycerol kinase GO:0004370|GO:0006072 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261|Reactome: R-HSA-75109 AFK25_09325 a19fbe7191a077617f6fb7009dc8a28f 168 Gene3D G3DSA:1.10.3450.10 4 106 5.3E-14 T 11-10-2018 AFK25_09325 a19fbe7191a077617f6fb7009dc8a28f 168 SUPERFAMILY SSF140663 2 125 6.8E-31 T 11-10-2018 IPR023203 TTHA0068-like superfamily AFK25_09325 a19fbe7191a077617f6fb7009dc8a28f 168 Pfam PF03745 Domain of unknown function (DUF309) 7 62 9.1E-21 T 11-10-2018 IPR005500 Protein of unknown function DUF309 AFK25_11940 9a6959810cf7c23f25810faf35584a91 175 SUPERFAMILY SSF52972 1 167 1.79E-46 T 11-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFK25_11940 9a6959810cf7c23f25810faf35584a91 175 Pfam PF01931 Protein of unknown function DUF84 6 160 1.6E-43 T 11-10-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 AFK25_11940 9a6959810cf7c23f25810faf35584a91 175 Gene3D G3DSA:3.90.950.10 1 173 5.0E-49 T 11-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFK25_14275 eb35e60dab371949de289b2ddaf9b4be 752 ProSitePatterns PS00850 Glycine radical domain signature. 722 730 - T 11-10-2018 IPR019777 Formate C-acetyltransferase glycine radical, conserved site AFK25_14275 eb35e60dab371949de289b2ddaf9b4be 752 TIGRFAM TIGR01255 pyr_form_ly_1: formate acetyltransferase 13 752 0.0 T 11-10-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 AFK25_14275 eb35e60dab371949de289b2ddaf9b4be 752 PIRSF PIRSF000379 10 752 0.0 T 11-10-2018 IPR005949 Formate acetyltransferase GO:0005737|GO:0005975|GO:0008861 KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 AFK25_14275 eb35e60dab371949de289b2ddaf9b4be 752 SUPERFAMILY SSF51998 7 752 1.07E-298 T 11-10-2018 AFK25_14275 eb35e60dab371949de289b2ddaf9b4be 752 Gene3D G3DSA:3.20.70.20 5 752 0.0 T 11-10-2018 AFK25_14275 eb35e60dab371949de289b2ddaf9b4be 752 Pfam PF01228 Glycine radical 627 733 3.0E-44 T 11-10-2018 IPR001150 Glycine radical domain GO:0003824 AFK25_14275 eb35e60dab371949de289b2ddaf9b4be 752 Pfam PF02901 Pyruvate formate lyase-like 24 611 1.5E-220 T 11-10-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 AFK25_12675 b759397eb90fd9c2b4828dba8a68c1f5 211 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 15 186 3.6E-29 T 11-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like AFK25_09875 7291166ab99dfcd8524921762aec33cc 189 Pfam PF09581 Stage III sporulation protein AF (Spore_III_AF) 12 183 9.3E-38 T 11-10-2018 IPR014245 Sporulation stage III, protein AF AFK25_09875 7291166ab99dfcd8524921762aec33cc 189 TIGRFAM TIGR02896 spore_III_AF: stage III sporulation protein AF 3 108 2.5E-35 T 11-10-2018 IPR014245 Sporulation stage III, protein AF AFK25_13500 764255526520ac4999286bff0368b295 321 Gene3D G3DSA:3.90.1720.10 20 151 3.7E-45 T 11-10-2018 AFK25_13500 764255526520ac4999286bff0368b295 321 SUPERFAMILY SSF54001 16 142 7.85E-43 T 11-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFK25_13500 764255526520ac4999286bff0368b295 321 Pfam PF00395 S-layer homology domain 210 252 7.3E-12 T 11-10-2018 IPR001119 S-layer homology domain AFK25_13500 764255526520ac4999286bff0368b295 321 Pfam PF00395 S-layer homology domain 150 193 5.1E-9 T 11-10-2018 IPR001119 S-layer homology domain AFK25_13500 764255526520ac4999286bff0368b295 321 Pfam PF00395 S-layer homology domain 268 311 5.1E-17 T 11-10-2018 IPR001119 S-layer homology domain AFK25_13500 764255526520ac4999286bff0368b295 321 Pfam PF00877 NlpC/P60 family 36 140 9.4E-31 T 11-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain AFK25_00490 aec7866e74d8e83a3e8516f344dd3132 486 SUPERFAMILY SSF52374 5 317 7.42E-115 T 11-10-2018 AFK25_00490 aec7866e74d8e83a3e8516f344dd3132 486 PRINTS PR00987 Glutamyl-tRNA synthetase signature 22 33 3.3E-29 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFK25_00490 aec7866e74d8e83a3e8516f344dd3132 486 PRINTS PR00987 Glutamyl-tRNA synthetase signature 8 20 3.3E-29 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFK25_00490 aec7866e74d8e83a3e8516f344dd3132 486 PRINTS PR00987 Glutamyl-tRNA synthetase signature 211 219 3.3E-29 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFK25_00490 aec7866e74d8e83a3e8516f344dd3132 486 PRINTS PR00987 Glutamyl-tRNA synthetase signature 195 205 3.3E-29 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFK25_00490 aec7866e74d8e83a3e8516f344dd3132 486 PRINTS PR00987 Glutamyl-tRNA synthetase signature 37 50 3.3E-29 T 11-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AFK25_00490 aec7866e74d8e83a3e8516f344dd3132 486 Gene3D G3DSA:1.10.10.350 391 486 3.6E-34 T 11-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFK25_00490 aec7866e74d8e83a3e8516f344dd3132 486 TIGRFAM TIGR00464 gltX_bact: glutamate--tRNA ligase 4 485 1.7E-190 T 11-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFK25_00490 aec7866e74d8e83a3e8516f344dd3132 486 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 11 22 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_00490 aec7866e74d8e83a3e8516f344dd3132 486 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 4 324 1.5E-135 T 11-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 AFK25_00490 aec7866e74d8e83a3e8516f344dd3132 486 Hamap MF_00022 Glutamate--tRNA ligase [gltX]. 4 485 35.002 T 11-10-2018 IPR004527 Glutamate-tRNA ligase, bacterial/mitochondrial GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFK25_00490 aec7866e74d8e83a3e8516f344dd3132 486 Gene3D G3DSA:3.40.50.620 1 333 2.3E-148 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_00490 aec7866e74d8e83a3e8516f344dd3132 486 SUPERFAMILY SSF48163 299 484 1.57E-48 T 11-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AFK25_12140 7d9e18e874baa5e30765c5eea1f6959a 241 Gene3D G3DSA:3.40.50.300 1 240 3.9E-69 T 11-10-2018 AFK25_12140 7d9e18e874baa5e30765c5eea1f6959a 241 SUPERFAMILY SSF52540 2 224 3.28E-60 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_12140 7d9e18e874baa5e30765c5eea1f6959a 241 Pfam PF00005 ABC transporter 19 164 5.6E-34 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_12140 7d9e18e874baa5e30765c5eea1f6959a 241 SMART SM00382 27 235 7.2E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_11815 950ab29e3a453a7e42c2a380e0312ee6 442 TIGRFAM TIGR00796 livcs: branched-chain amino acid transport system II carrier protein 10 417 1.9E-153 T 11-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 AFK25_11815 950ab29e3a453a7e42c2a380e0312ee6 442 Pfam PF05525 Branched-chain amino acid transport protein 3 431 1.8E-164 T 11-10-2018 IPR004685 Branched-chain amino acid transport system II carrier protein GO:0015658|GO:0015803|GO:0016021 AFK25_10690 40a3ba29954db5772a16dc70adcf9c5f 354 Pfam PF01594 AI-2E family transporter 22 346 2.2E-78 T 11-10-2018 IPR002549 Transmembrane protein TqsA-like AFK25_11905 f8c202cb9022104fe8405f2f8baa1ee6 109 Pfam PF11009 Protein of unknown function (DUF2847) 3 100 5.5E-33 T 11-10-2018 IPR022551 Protein of unknown function DUF2847 AFK25_11905 f8c202cb9022104fe8405f2f8baa1ee6 109 SUPERFAMILY SSF52833 3 80 7.16E-6 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_11905 f8c202cb9022104fe8405f2f8baa1ee6 109 Gene3D G3DSA:3.40.30.10 1 106 1.6E-34 T 11-10-2018 AFK25_11905 f8c202cb9022104fe8405f2f8baa1ee6 109 TIGRFAM TIGR04019 B_thiol_YtxJ: bacillithiol system protein YtxJ 3 103 2.5E-35 T 11-10-2018 IPR022551 Protein of unknown function DUF2847 AFK25_10055 3545bc6628e8d1c5e83abac5d31315c1 367 Gene3D G3DSA:3.40.50.12710 3 366 1.6E-95 T 11-10-2018 IPR038375 Protein arginine methyltransferase NDUFAF7 superfamily Reactome: R-HSA-6799198 AFK25_10055 3545bc6628e8d1c5e83abac5d31315c1 367 SUPERFAMILY SSF53335 18 362 1.55E-74 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_10055 3545bc6628e8d1c5e83abac5d31315c1 367 Pfam PF02636 Putative S-adenosyl-L-methionine-dependent methyltransferase 83 300 5.2E-41 T 11-10-2018 IPR003788 Protein arginine methyltransferase NDUFAF7 Reactome: R-HSA-6799198 AFK25_11500 0225bbe4d89cf548feba94a745fc2754 436 Gene3D G3DSA:3.40.190.10 154 413 1.5E-92 T 11-10-2018 AFK25_11500 0225bbe4d89cf548feba94a745fc2754 436 Pfam PF13416 Bacterial extracellular solute-binding protein 57 364 1.9E-47 T 11-10-2018 IPR006059 Bacterial extracellular solute-binding protein AFK25_11500 0225bbe4d89cf548feba94a745fc2754 436 SUPERFAMILY SSF53850 20 433 4.19E-77 T 11-10-2018 AFK25_11500 0225bbe4d89cf548feba94a745fc2754 436 Gene3D G3DSA:3.40.190.10 59 359 1.5E-92 T 11-10-2018 AFK25_04155 ee695518cfe5f39991ca837d75070ff4 304 SUPERFAMILY SSF103481 190 288 1.44E-17 T 11-10-2018 AFK25_04155 ee695518cfe5f39991ca837d75070ff4 304 SUPERFAMILY SSF103481 41 141 1.96E-15 T 11-10-2018 AFK25_04155 ee695518cfe5f39991ca837d75070ff4 304 Pfam PF00892 EamA-like transporter family 6 139 2.9E-24 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFK25_04155 ee695518cfe5f39991ca837d75070ff4 304 Pfam PF00892 EamA-like transporter family 150 286 2.6E-22 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFK25_06265 b94c63756f7b419c7f87f77dace0150e 324 Pfam PF13614 AAA domain 6 227 5.9E-37 T 11-10-2018 IPR025669 AAA domain AFK25_06265 b94c63756f7b419c7f87f77dace0150e 324 Gene3D G3DSA:3.40.50.300 1 320 1.8E-58 T 11-10-2018 AFK25_06265 b94c63756f7b419c7f87f77dace0150e 324 SUPERFAMILY SSF52540 5 317 1.86E-32 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_10875 aa02683224b70825b20d9f6dd69507c0 367 TIGRFAM TIGR00550 nadA: quinolinate synthetase complex, A subunit 20 365 1.9E-119 T 11-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFK25_10875 aa02683224b70825b20d9f6dd69507c0 367 Gene3D G3DSA:3.40.50.10800 229 314 2.2E-83 T 11-10-2018 AFK25_10875 aa02683224b70825b20d9f6dd69507c0 367 Hamap MF_00569 Quinolinate synthase A [nadA]. 21 366 56.767 T 11-10-2018 IPR023515 Quinolinate synthase A, type 3 GO:0016765 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFK25_10875 aa02683224b70825b20d9f6dd69507c0 367 Gene3D G3DSA:3.40.50.10800 111 364 2.2E-83 T 11-10-2018 AFK25_10875 aa02683224b70825b20d9f6dd69507c0 367 SUPERFAMILY SSF142754 33 365 2.35E-99 T 11-10-2018 IPR036094 Quinolinate synthetase A superfamily GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFK25_10875 aa02683224b70825b20d9f6dd69507c0 367 Gene3D G3DSA:3.40.50.10800 28 347 2.2E-83 T 11-10-2018 AFK25_10875 aa02683224b70825b20d9f6dd69507c0 367 Pfam PF02445 Quinolinate synthetase A protein 28 365 2.7E-108 T 11-10-2018 IPR003473 Quinolinate synthetase A GO:0008987|GO:0009435|GO:0051539 MetaCyc: PWY-5316|MetaCyc: PWY-7342 AFK25_02595 c39b6e0db10940b20702a0371509b7ca 303 Pfam PF00849 RNA pseudouridylate synthase 92 244 5.5E-33 T 11-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_02595 c39b6e0db10940b20702a0371509b7ca 303 Gene3D G3DSA:3.30.2350.10 77 288 1.6E-70 T 11-10-2018 AFK25_02595 c39b6e0db10940b20702a0371509b7ca 303 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 135 149 - T 11-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_02595 c39b6e0db10940b20702a0371509b7ca 303 SUPERFAMILY SSF55120 77 289 2.72E-69 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_02595 c39b6e0db10940b20702a0371509b7ca 303 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 18 288 1.6E-76 T 11-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_08400 9bcfe37014c509fd3d9319b862c6ded3 103 Gene3D G3DSA:1.20.58.1000 2 103 7.8E-40 T 11-10-2018 IPR038390 Metal-sensitive transcriptional repressor superfamily AFK25_08400 9bcfe37014c509fd3d9319b862c6ded3 103 Pfam PF02583 Metal-sensitive transcriptional repressor 22 99 2.9E-31 T 11-10-2018 IPR003735 Metal-sensitive transcriptional repressor GO:0003677|GO:0006355|GO:0046872 AFK25_04305 6ffb6aec2f8d6662eb0a6f5d31e88372 271 Gene3D G3DSA:1.10.3720.10 1 263 5.3E-73 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_04305 6ffb6aec2f8d6662eb0a6f5d31e88372 271 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 88 265 3.1E-22 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_04305 6ffb6aec2f8d6662eb0a6f5d31e88372 271 SUPERFAMILY SSF161098 3 270 1.21E-76 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_03115 47dd8431453fb0b5315730c856caa276 118 ProDom PD067392 MEMBRANE UPF0344 TRANSMEMBRANE MW0851 BCE1257 SIMILAR YISL SAR0931 BCE33L1051 BT9727_1053 1 102 2.0E-19 T 11-10-2018 IPR010899 Protein of unknown function UPF0344 AFK25_03115 47dd8431453fb0b5315730c856caa276 118 Pfam PF07457 Protein of unknown function (DUF1516) 2 107 6.5E-36 T 11-10-2018 IPR010899 Protein of unknown function UPF0344 AFK25_03115 47dd8431453fb0b5315730c856caa276 118 Hamap MF_01536 UPF0344 protein . 1 117 16.477 T 11-10-2018 IPR010899 Protein of unknown function UPF0344 AFK25_08630 5d477fd9d91b9becab06baa51ca184bc 428 SUPERFAMILY SSF46458 24 174 4.82E-22 T 11-10-2018 IPR009050 Globin-like superfamily AFK25_08630 5d477fd9d91b9becab06baa51ca184bc 428 SMART SM00283 191 424 6.0E-24 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_08630 5d477fd9d91b9becab06baa51ca184bc 428 SUPERFAMILY SSF58104 197 427 3.4E-46 T 11-10-2018 AFK25_08630 5d477fd9d91b9becab06baa51ca184bc 428 Gene3D G3DSA:1.10.490.10 18 172 5.9E-29 T 11-10-2018 IPR012292 Globin/Protoglobin GO:0019825|GO:0020037 AFK25_08630 5d477fd9d91b9becab06baa51ca184bc 428 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 266 417 2.8E-28 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_08630 5d477fd9d91b9becab06baa51ca184bc 428 Gene3D G3DSA:1.10.287.950 173 428 1.2E-44 T 11-10-2018 AFK25_08630 5d477fd9d91b9becab06baa51ca184bc 428 Pfam PF11563 Protoglobin 27 181 4.0E-29 T 11-10-2018 AFK25_06570 f4a30c4b9f8746059a6ae4cdc6bef137 76 SUPERFAMILY SSF52833 1 75 1.38E-19 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_06570 f4a30c4b9f8746059a6ae4cdc6bef137 76 Pfam PF13192 Thioredoxin domain 1 75 2.6E-27 T 11-10-2018 IPR012336 Thioredoxin-like fold AFK25_06570 f4a30c4b9f8746059a6ae4cdc6bef137 76 Gene3D G3DSA:3.40.30.10 1 75 5.2E-30 T 11-10-2018 AFK25_06570 f4a30c4b9f8746059a6ae4cdc6bef137 76 TIGRFAM TIGR00412 redox_disulf_2: redox-active disulfide protein 2 1 76 6.1E-22 T 11-10-2018 IPR005243 Redox-active disulphide protein 2 AFK25_06570 f4a30c4b9f8746059a6ae4cdc6bef137 76 PIRSF PIRSF037031 1 76 4.9E-32 T 11-10-2018 IPR005243 Redox-active disulphide protein 2 AFK25_10320 c86f1e91001c268f0bf42658388f4685 320 SUPERFAMILY SSF52540 103 278 7.23E-40 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_10320 c86f1e91001c268f0bf42658388f4685 320 Gene3D G3DSA:3.40.50.300 110 316 1.9E-74 T 11-10-2018 AFK25_10320 c86f1e91001c268f0bf42658388f4685 320 Pfam PF02562 PhoH-like protein 113 316 2.0E-96 T 11-10-2018 IPR003714 PhoH-like protein GO:0005524 AFK25_07595 c8e391ca6500e3c6b8f3ff382e34e58c 269 Pfam PF02557 D-alanyl-D-alanine carboxypeptidase 117 246 2.1E-45 T 11-10-2018 IPR003709 Peptidase M15B GO:0006508|GO:0008233 AFK25_07595 c8e391ca6500e3c6b8f3ff382e34e58c 269 SUPERFAMILY SSF55166 103 254 6.02E-40 T 11-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFK25_07595 c8e391ca6500e3c6b8f3ff382e34e58c 269 Gene3D G3DSA:3.30.1380.10 53 269 6.4E-85 T 11-10-2018 IPR009045 Hedgehog signalling/DD-peptidase zinc-binding domain superfamily Reactome: R-HSA-373080|Reactome: R-HSA-5358346|Reactome: R-HSA-5362798|Reactome: R-HSA-5632681|Reactome: R-HSA-5632684|Reactome: R-HSA-5635838|Reactome: R-HSA-5658034 AFK25_00350 4e9c632f83b73235099012619e13146d 821 Pfam PF07228 Stage II sporulation protein E (SpoIIE) 619 804 2.7E-35 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFK25_00350 4e9c632f83b73235099012619e13146d 821 SMART SM00332 572 802 1.0E-4 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFK25_00350 4e9c632f83b73235099012619e13146d 821 TIGRFAM TIGR02865 spore_II_E: stage II sporulation protein E 44 804 4.4E-266 T 11-10-2018 IPR014221 Sporulation stage II, protein E KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFK25_00350 4e9c632f83b73235099012619e13146d 821 SMART SM00331 592 804 1.8E-46 T 11-10-2018 IPR001932 PPM-type phosphatase domain GO:0003824 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFK25_00350 4e9c632f83b73235099012619e13146d 821 Gene3D G3DSA:3.60.40.10 586 821 3.4E-52 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFK25_00350 4e9c632f83b73235099012619e13146d 821 SUPERFAMILY SSF81606 594 805 1.02E-22 T 11-10-2018 IPR036457 PPM-type phosphatase domain superfamily KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFK25_12785 602c2b0feb031ae80c75ffca87330b7a 82 ProDom PD058325 YUSG BH3483 10 82 4.0E-13 T 11-10-2018 IPR020140 Uncharacterised protein family YusG AFK25_12785 602c2b0feb031ae80c75ffca87330b7a 82 Pfam PF10830 Protein of unknown function (DUF2553) 9 82 5.7E-29 T 11-10-2018 IPR020140 Uncharacterised protein family YusG AFK25_00275 94a8cc801c5e3d65bd2d9278a7293c51 316 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 10 316 7.6E-134 T 11-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFK25_00275 94a8cc801c5e3d65bd2d9278a7293c51 316 Pfam PF14572 Phosphoribosyl synthetase-associated domain 207 315 2.5E-25 T 11-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFK25_00275 94a8cc801c5e3d65bd2d9278a7293c51 316 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 9 125 6.4E-53 T 11-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AFK25_00275 94a8cc801c5e3d65bd2d9278a7293c51 316 SMART SM01400 9 125 5.2E-84 T 11-10-2018 AFK25_00275 94a8cc801c5e3d65bd2d9278a7293c51 316 Hamap MF_00583_B Putative ribose-phosphate pyrophosphokinase [prs]. 9 316 52.311 T 11-10-2018 IPR037515 Ribose-phosphate pyrophosphokinase, bacterial-type GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 AFK25_00275 94a8cc801c5e3d65bd2d9278a7293c51 316 Gene3D G3DSA:3.40.50.2020 12 304 1.2E-130 T 11-10-2018 AFK25_00275 94a8cc801c5e3d65bd2d9278a7293c51 316 ProSitePatterns PS00114 Phosphoribosyl pyrophosphate synthase signature. 133 148 - T 11-10-2018 IPR000842 Phosphoribosyl pyrophosphate synthetase, conserved site GO:0000287|GO:0004749|GO:0009156|GO:0044249 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1|Reactome: R-HSA-73843 AFK25_00275 94a8cc801c5e3d65bd2d9278a7293c51 316 SUPERFAMILY SSF53271 74 307 5.23E-68 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like AFK25_00275 94a8cc801c5e3d65bd2d9278a7293c51 316 Gene3D G3DSA:3.40.50.2020 152 292 1.2E-130 T 11-10-2018 AFK25_08015 870b2088e3122d324d8bdd6ea20cc369 219 Pfam PF10112 5-bromo-4-chloroindolyl phosphate hydrolysis protein 8 188 1.3E-47 T 11-10-2018 IPR018770 5-bromo-4-chloroindolyl phosphate hydrolysis protein AFK25_08825 d1eef178462735495c82cbd9c8bcf7ec 257 TIGRFAM TIGR02878 spore_ypjB: sporulation protein YpjB 25 253 1.3E-81 T 11-10-2018 IPR014231 Sporulation protein YpjB AFK25_08825 d1eef178462735495c82cbd9c8bcf7ec 257 Pfam PF09577 Sporulation protein YpjB (SpoYpjB) 26 251 3.9E-91 T 11-10-2018 IPR014231 Sporulation protein YpjB AFK25_11360 92a0d080c8751ecfe3e5c39b45668373 1040 Gene3D G3DSA:1.20.1640.10 833 1034 8.1E-7 T 11-10-2018 AFK25_11360 92a0d080c8751ecfe3e5c39b45668373 1040 Pfam PF03176 MMPL family 44 366 4.7E-62 T 11-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFK25_11360 92a0d080c8751ecfe3e5c39b45668373 1040 Pfam PF03176 MMPL family 740 1038 2.0E-49 T 11-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AFK25_11360 92a0d080c8751ecfe3e5c39b45668373 1040 SUPERFAMILY SSF82866 156 341 1.26E-30 T 11-10-2018 AFK25_11360 92a0d080c8751ecfe3e5c39b45668373 1040 Gene3D G3DSA:1.20.1640.10 132 349 7.2E-12 T 11-10-2018 AFK25_11360 92a0d080c8751ecfe3e5c39b45668373 1040 SUPERFAMILY SSF82866 827 1037 2.62E-31 T 11-10-2018 AFK25_11360 92a0d080c8751ecfe3e5c39b45668373 1040 SUPERFAMILY SSF58104 485 693 9.94E-6 T 11-10-2018 AFK25_01485 68c2f267a518cbd3731450881b55db73 317 Gene3D G3DSA:1.20.1530.20 10 316 2.4E-41 T 11-10-2018 IPR038770 Sodium/solute symporter superfamily AFK25_01485 68c2f267a518cbd3731450881b55db73 317 Pfam PF01758 Sodium Bile acid symporter family 43 225 7.6E-29 T 11-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 AFK25_14355 ff4f5daa89964d1f5fd5e39caf86e7a8 141 Pfam PF10916 Protein of unknown function (DUF2712) 30 141 1.5E-51 T 11-10-2018 IPR020208 Protein of unknown function DUF2712 AFK25_14355 ff4f5daa89964d1f5fd5e39caf86e7a8 141 ProDom PD088182 YYBN 1 140 4.0E-31 T 11-10-2018 IPR020208 Protein of unknown function DUF2712 AFK25_00410 4162eb78b4d491090b083ee50c06b968 290 ProSitePatterns PS00793 Dihydropteroate synthase signature 2. 66 79 - T 11-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_00410 4162eb78b4d491090b083ee50c06b968 290 Gene3D G3DSA:3.20.20.20 14 286 1.6E-116 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_00410 4162eb78b4d491090b083ee50c06b968 290 SUPERFAMILY SSF51717 17 283 7.06E-105 T 11-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_00410 4162eb78b4d491090b083ee50c06b968 290 ProSitePatterns PS00792 Dihydropteroate synthase signature 1. 32 47 - T 11-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_00410 4162eb78b4d491090b083ee50c06b968 290 Pfam PF00809 Pterin binding enzyme 33 266 8.0E-91 T 11-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AFK25_00410 4162eb78b4d491090b083ee50c06b968 290 TIGRFAM TIGR01496 DHPS: dihydropteroate synthase 32 281 1.5E-101 T 11-10-2018 IPR006390 Dihydropteroate synthase GO:0004156|GO:0009396 KEGG: 00790+2.5.1.15|MetaCyc: PWY-6614 AFK25_03745 9e229451c9d3cfbc1a4e7509685d6e63 131 SUPERFAMILY SSF81330 11 121 1.02E-34 T 11-10-2018 IPR036019 Gated mechanosensitive channel AFK25_03745 9e229451c9d3cfbc1a4e7509685d6e63 131 ProSitePatterns PS01327 Large-conductance mechanosensitive channels mscL family signature. 11 24 - T 11-10-2018 IPR019823 Large-conductance mechanosensitive channel, conserved site AFK25_03745 9e229451c9d3cfbc1a4e7509685d6e63 131 Hamap MF_00115 Large-conductance mechanosensitive channel [mscL]. 1 126 24.099 T 11-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 AFK25_03745 9e229451c9d3cfbc1a4e7509685d6e63 131 Pfam PF01741 Large-conductance mechanosensitive channel, MscL 1 125 9.2E-47 T 11-10-2018 IPR037673 Large-conductance mechanosensitive channel/anditomin synthesis protein L AFK25_03745 9e229451c9d3cfbc1a4e7509685d6e63 131 Gene3D G3DSA:1.10.1200.120 1 128 3.1E-42 T 11-10-2018 IPR036019 Gated mechanosensitive channel AFK25_03745 9e229451c9d3cfbc1a4e7509685d6e63 131 TIGRFAM TIGR00220 mscL: large conductance mechanosensitive channel protein 1 127 4.0E-51 T 11-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 AFK25_03745 9e229451c9d3cfbc1a4e7509685d6e63 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 84 93 1.4E-12 T 11-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 AFK25_03745 9e229451c9d3cfbc1a4e7509685d6e63 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 4 18 1.4E-12 T 11-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 AFK25_03745 9e229451c9d3cfbc1a4e7509685d6e63 131 PRINTS PR01264 Bacterial mechano-sensitive ion channel signature 75 83 1.4E-12 T 11-10-2018 IPR001185 Large-conductance mechanosensitive channel GO:0008381|GO:0016021|GO:0034220 AFK25_05325 af7c02991dcf5c33c951475ad991b9af 303 Pfam PF00849 RNA pseudouridylate synthase 88 241 1.4E-35 T 11-10-2018 IPR006145 Pseudouridine synthase, RsuA/RluB/C/D/E/F GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_05325 af7c02991dcf5c33c951475ad991b9af 303 ProSitePatterns PS01129 Rlu family of pseudouridine synthase signature. 134 148 - T 11-10-2018 IPR006224 Pseudouridine synthase, RluC/RluD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_05325 af7c02991dcf5c33c951475ad991b9af 303 Gene3D G3DSA:3.30.2350.10 81 303 8.1E-78 T 11-10-2018 AFK25_05325 af7c02991dcf5c33c951475ad991b9af 303 Gene3D G3DSA:3.10.290.10 2 69 6.6E-20 T 11-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AFK25_05325 af7c02991dcf5c33c951475ad991b9af 303 Pfam PF01479 S4 domain 15 61 3.4E-13 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_05325 af7c02991dcf5c33c951475ad991b9af 303 TIGRFAM TIGR00005 rluA_subfam: pseudouridine synthase, RluA family 11 300 1.4E-105 T 11-10-2018 IPR006225 Pseudouridine synthase, RluC/RluD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_05325 af7c02991dcf5c33c951475ad991b9af 303 SUPERFAMILY SSF55174 15 102 4.32E-16 T 11-10-2018 AFK25_05325 af7c02991dcf5c33c951475ad991b9af 303 SMART SM00363 15 79 4.1E-12 T 11-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_05325 af7c02991dcf5c33c951475ad991b9af 303 SUPERFAMILY SSF55120 73 301 1.21E-82 T 11-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AFK25_06445 1d3bb0979d566ad2a7d4c7fec40c5ff4 264 Pfam PF12679 ABC-2 family transporter protein 2 262 1.7E-46 T 11-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 AFK25_06440 43859bf18e5b2a8e36576c49d29c28fd 290 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_06440 43859bf18e5b2a8e36576c49d29c28fd 290 Pfam PF00005 ABC transporter 20 156 4.3E-27 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_06440 43859bf18e5b2a8e36576c49d29c28fd 290 SMART SM00382 28 213 6.8E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_06440 43859bf18e5b2a8e36576c49d29c28fd 290 SUPERFAMILY SSF52540 3 224 2.62E-55 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_06440 43859bf18e5b2a8e36576c49d29c28fd 290 Gene3D G3DSA:3.40.50.300 1 231 9.0E-59 T 11-10-2018 AFK25_08190 1eb2d899f307dc2c581a449015df88a1 340 Pfam PF01609 Transposase DDE domain 75 283 2.8E-29 T 11-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 AFK25_08190 1eb2d899f307dc2c581a449015df88a1 340 SUPERFAMILY SSF53098 49 307 1.82E-29 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_05985 5564be05b41d6af0c4c10ca5d9fc7792 241 SMART SM00866 95 233 1.2E-23 T 11-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFK25_05985 5564be05b41d6af0c4c10ca5d9fc7792 241 Gene3D G3DSA:3.40.1410.10 83 240 1.7E-30 T 11-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AFK25_05985 5564be05b41d6af0c4c10ca5d9fc7792 241 SUPERFAMILY SSF64288 62 239 8.64E-39 T 11-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AFK25_05985 5564be05b41d6af0c4c10ca5d9fc7792 241 Pfam PF00392 Bacterial regulatory proteins, gntR family 10 73 1.8E-22 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_05985 5564be05b41d6af0c4c10ca5d9fc7792 241 Pfam PF07702 UTRA domain 96 232 2.4E-27 T 11-10-2018 IPR011663 UbiC transcription regulator-associated GO:0003677|GO:0006355 AFK25_05985 5564be05b41d6af0c4c10ca5d9fc7792 241 Gene3D G3DSA:1.10.10.10 3 75 3.6E-26 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_05985 5564be05b41d6af0c4c10ca5d9fc7792 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 47 63 5.2E-10 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_05985 5564be05b41d6af0c4c10ca5d9fc7792 241 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 33 47 5.2E-10 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_05985 5564be05b41d6af0c4c10ca5d9fc7792 241 SUPERFAMILY SSF46785 5 84 3.18E-24 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_05985 5564be05b41d6af0c4c10ca5d9fc7792 241 SMART SM00345 14 73 1.2E-22 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_01445 ef3a9491c5341185cb5ad180bbcd18bd 201 TIGRFAM TIGR02842 CyoC: cytochrome o ubiquinol oxidase, subunit III 21 200 1.0E-67 T 11-10-2018 IPR014206 Cytochrome o ubiquinol oxidase, subunit III GO:0005886|GO:0008827|GO:0019646 AFK25_01445 ef3a9491c5341185cb5ad180bbcd18bd 201 Gene3D G3DSA:1.20.120.80 15 200 7.5E-53 T 11-10-2018 IPR013833 Cytochrome c oxidase, subunit III, 4-helical bundle GO:0004129|GO:0016020|GO:0022904 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01445 ef3a9491c5341185cb5ad180bbcd18bd 201 Pfam PF00510 Cytochrome c oxidase subunit III 23 198 9.7E-14 T 11-10-2018 IPR000298 Cytochrome c oxidase subunit III-like GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_01445 ef3a9491c5341185cb5ad180bbcd18bd 201 TIGRFAM TIGR02897 QoxC: cytochrome aa3 quinol oxidase, subunit III 12 200 4.2E-90 T 11-10-2018 IPR014246 Quinol oxidase subunit III GO:0015002|GO:0016021|GO:0042773 AFK25_01445 ef3a9491c5341185cb5ad180bbcd18bd 201 SUPERFAMILY SSF81452 19 198 4.58E-54 T 11-10-2018 IPR035973 Cytochrome c oxidase subunit III-like superfamily GO:0015002|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_09615 f19ae5861ed16a331cc49c20b3d82565 649 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 243 263 2.1E-53 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFK25_09615 f19ae5861ed16a331cc49c20b3d82565 649 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 158 180 2.1E-53 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFK25_09615 f19ae5861ed16a331cc49c20b3d82565 649 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 79 105 2.1E-53 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFK25_09615 f19ae5861ed16a331cc49c20b3d82565 649 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 131 148 2.1E-53 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFK25_09615 f19ae5861ed16a331cc49c20b3d82565 649 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 209 235 2.1E-53 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFK25_09615 f19ae5861ed16a331cc49c20b3d82565 649 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 273 293 2.1E-53 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFK25_09615 f19ae5861ed16a331cc49c20b3d82565 649 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 293 309 2.1E-53 T 11-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFK25_09615 f19ae5861ed16a331cc49c20b3d82565 649 Pfam PF01578 Cytochrome C assembly protein 89 294 2.7E-37 T 11-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 AFK25_09615 f19ae5861ed16a331cc49c20b3d82565 649 Pfam PF16327 Cytochrome c-type biogenesis protein CcmF C-terminal 313 641 7.7E-62 T 11-10-2018 IPR032523 Cytochrome c-type biogenesis protein CcmF, C-terminal AFK25_07575 05d3be2bb9bbdba02886bd19449d5e2b 299 SUPERFAMILY SSF103481 40 147 3.27E-12 T 11-10-2018 AFK25_07575 05d3be2bb9bbdba02886bd19449d5e2b 299 Pfam PF00892 EamA-like transporter family 6 146 4.4E-14 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFK25_07575 05d3be2bb9bbdba02886bd19449d5e2b 299 TIGRFAM TIGR00688 rarD: protein RarD 7 260 5.3E-70 T 11-10-2018 IPR004626 RarD protein GO:0005887 AFK25_07575 05d3be2bb9bbdba02886bd19449d5e2b 299 SUPERFAMILY SSF103481 200 288 1.44E-8 T 11-10-2018 AFK25_08560 41ac0b3d55ad3ea80c952164aef6d19e 108 SUPERFAMILY SSF101386 22 84 2.99E-6 T 11-10-2018 AFK25_03415 9ac6c2943a0b5d5a48777dcacb4c4404 233 SUPERFAMILY SSF53474 53 214 2.03E-12 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold AFK25_03415 9ac6c2943a0b5d5a48777dcacb4c4404 233 Gene3D G3DSA:3.40.50.1820 36 231 1.4E-8 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold AFK25_14300 5d90231aaf09733e9a04729ccbffe142 289 Gene3D G3DSA:3.90.640.20 196 289 7.1E-35 T 11-10-2018 IPR037126 PdaC/RsiV-like superfamily AFK25_14300 5d90231aaf09733e9a04729ccbffe142 289 Pfam PF11738 Protein of unknown function (DUF3298) 200 275 4.1E-15 T 11-10-2018 IPR021729 Domain of unknown function DUF3298 AFK25_14300 5d90231aaf09733e9a04729ccbffe142 289 Gene3D G3DSA:3.30.565.40 79 195 5.9E-25 T 11-10-2018 AFK25_14085 1941508292a0be3dbc431639c2d849a1 440 Pfam PF01966 HD domain 68 187 4.7E-17 T 11-10-2018 IPR006674 HD domain AFK25_14085 1941508292a0be3dbc431639c2d849a1 440 SMART SM00471 64 194 1.1E-13 T 11-10-2018 IPR003607 HD/PDEase domain AFK25_14085 1941508292a0be3dbc431639c2d849a1 440 Gene3D G3DSA:1.10.3210.10 18 409 2.5E-168 T 11-10-2018 AFK25_14085 1941508292a0be3dbc431639c2d849a1 440 Gene3D G3DSA:1.20.1250.30 242 420 2.5E-168 T 11-10-2018 AFK25_14085 1941508292a0be3dbc431639c2d849a1 440 SUPERFAMILY SSF109604 13 425 9.42E-124 T 11-10-2018 AFK25_13075 9266d0eb11e0a47d48f5f254f754f857 389 SUPERFAMILY SSF50156 305 385 2.76E-13 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 AFK25_13075 9266d0eb11e0a47d48f5f254f754f857 389 Gene3D G3DSA:2.30.42.10 283 371 1.5E-11 T 11-10-2018 AFK25_13075 9266d0eb11e0a47d48f5f254f754f857 389 SMART SM00228 296 362 0.0026 T 11-10-2018 IPR001478 PDZ domain GO:0005515 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 Gene3D G3DSA:2.30.210.10 572 587 2.7E-287 T 11-10-2018 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 SUPERFAMILY SSF52374 3 625 6.88E-153 T 11-10-2018 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 Pfam PF09334 tRNA synthetases class I (M) 39 170 2.1E-18 T 11-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 Hamap MF_00049_B Leucine--tRNA ligase [leuS]. 2 804 23.827 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 Gene3D G3DSA:3.10.20.590 745 804 9.1E-24 T 11-10-2018 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 SUPERFAMILY SSF50677 224 410 4.6E-58 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 Gene3D G3DSA:3.40.50.620 32 571 2.7E-287 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 Gene3D G3DSA:3.90.740.10 226 410 2.7E-287 T 11-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 TIGRFAM TIGR00396 leuS_bact: leucine--tRNA ligase 4 804 0.0 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 Pfam PF13603 Leucyl-tRNA synthetase, Domain 2 219 399 2.3E-72 T 11-10-2018 IPR025709 Leucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 KEGG: 00970+6.1.1.4 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 Pfam PF08264 Anticodon-binding domain of tRNA 656 767 1.2E-21 T 11-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 SUPERFAMILY SSF47323 619 804 5.42E-42 T 11-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 Gene3D G3DSA:1.10.730.10 599 741 9.3E-48 T 11-10-2018 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 42 52 - T 11-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 412 604 5.9E-20 T 11-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 557 567 2.4E-58 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 524 546 2.4E-58 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 152 168 2.4E-58 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 213 232 2.4E-58 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 126 143 2.4E-58 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 184 197 2.4E-58 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFK25_12045 5a9c01123fe5c046e1ccf9b842f273db 805 PRINTS PR00985 Leucyl-tRNA synthetase signature 485 503 2.4E-58 T 11-10-2018 IPR002302 Leucine-tRNA ligase GO:0000166|GO:0004823|GO:0005524|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-379726 AFK25_09400 30520a1007339e3ecfed98c79d6083b2 206 Gene3D G3DSA:2.60.480.10 1 94 1.1E-10 T 11-10-2018 IPR038548 Stage V sporulation protein AA, N-terminal domain superfamily AFK25_09400 30520a1007339e3ecfed98c79d6083b2 206 Pfam PF12164 Stage V sporulation protein AA 3 87 1.5E-19 T 11-10-2018 IPR021997 Stage V sporulation protein AA AFK25_10195 50c5781fbff1b2d121b17918b7ce9749 103 Gene3D G3DSA:3.10.350.10 44 98 1.9E-6 T 11-10-2018 IPR036779 LysM domain superfamily AFK25_10195 50c5781fbff1b2d121b17918b7ce9749 103 ProDom PD067165 YQFZ MEMBRANE WALL BH1402 TRANSMEMBRANE OB1935 CELL 1 100 3.0E-18 T 11-10-2018 IPR020506 Uncharacterised protein family YqfZ AFK25_09935 8292daa1cca74706114a11296de3f028 113 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 4 113 4.0E-18 T 11-10-2018 AFK25_05295 c63fb637256ebd0607a3e79339973c78 140 Gene3D G3DSA:3.30.110.150 45 138 3.6E-34 T 11-10-2018 IPR038594 SepF-like superfamily AFK25_05295 c63fb637256ebd0607a3e79339973c78 140 Hamap MF_01197 Cell division protein SepF [sepF]. 1 131 20.697 T 11-10-2018 IPR023052 Cell division protein SepF GO:0090529 AFK25_05295 c63fb637256ebd0607a3e79339973c78 140 Pfam PF04472 Cell division protein SepF 53 123 1.8E-30 T 11-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 AFK25_11895 4a3f6245c1cadaf297060a34b961e61e 130 Gene3D G3DSA:1.10.287.950 21 127 1.9E-5 T 11-10-2018 AFK25_11895 4a3f6245c1cadaf297060a34b961e61e 130 Pfam PF06103 Bacterial protein of unknown function (DUF948) 9 94 1.6E-24 T 11-10-2018 IPR009293 Uncharacterised protein family UPF0478 AFK25_08780 d3f3e95c9ff9a2ca7f8263307e01aba6 276 PIRSF PIRSF000388 1 265 8.1E-113 T 11-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 AFK25_08780 d3f3e95c9ff9a2ca7f8263307e01aba6 276 Hamap MF_00156 3-methyl-2-oxobutanoate hydroxymethyltransferase [panB]. 2 262 43.22 T 11-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 AFK25_08780 d3f3e95c9ff9a2ca7f8263307e01aba6 276 Pfam PF02548 Ketopantoate hydroxymethyltransferase 6 257 5.9E-114 T 11-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 AFK25_08780 d3f3e95c9ff9a2ca7f8263307e01aba6 276 TIGRFAM TIGR00222 panB: 3-methyl-2-oxobutanoate hydroxymethyltransferase 1 262 6.3E-119 T 11-10-2018 IPR003700 Ketopantoate hydroxymethyltransferase GO:0003864|GO:0015940 KEGG: 00770+2.1.2.11|MetaCyc: PWY-6654 AFK25_08780 d3f3e95c9ff9a2ca7f8263307e01aba6 276 SUPERFAMILY SSF51621 3 262 7.07E-110 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFK25_08780 d3f3e95c9ff9a2ca7f8263307e01aba6 276 Gene3D G3DSA:3.20.20.60 2 272 2.0E-118 T 11-10-2018 AFK25_09390 0c8a386705ad84955e8ef5ba176c925c 114 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 3 112 3.8E-22 T 11-10-2018 IPR005562 SpoVA AFK25_04885 a91f9692073ccddf7785a77920956f52 126 Gene3D G3DSA:3.30.310.120 51 125 2.7E-27 T 11-10-2018 AFK25_04885 a91f9692073ccddf7785a77920956f52 126 Pfam PF08968 Domain of unknown function (DUF1885) 4 125 5.4E-54 T 11-10-2018 IPR015062 Protein of unknown function DUF1885 AFK25_04885 a91f9692073ccddf7785a77920956f52 126 SUPERFAMILY SSF111171 6 124 5.75E-36 T 11-10-2018 IPR036294 Rbstp2229-like superfamily AFK25_04885 a91f9692073ccddf7785a77920956f52 126 Gene3D G3DSA:1.20.5.850 3 50 3.3E-20 T 11-10-2018 AFK25_00805 984b827886887731999ff0b1f4232fd9 253 SUPERFAMILY SSF88713 16 242 5.19E-54 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFK25_00805 984b827886887731999ff0b1f4232fd9 253 Pfam PF01522 Polysaccharide deacetylase 54 174 9.3E-25 T 11-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFK25_00805 984b827886887731999ff0b1f4232fd9 253 TIGRFAM TIGR02764 spore_ybaN_pdaB: polysaccharide deacetylase family sporulation protein PdaB 52 242 8.9E-77 T 11-10-2018 IPR014132 Sporulation polysaccharide deacetylase, PdaB AFK25_00805 984b827886887731999ff0b1f4232fd9 253 Gene3D G3DSA:3.20.20.370 28 251 7.1E-57 T 11-10-2018 AFK25_02255 7b2e7c62f2330a42f2e8001f11ae979c 134 Gene3D G3DSA:1.10.260.40 1 130 9.3E-28 T 11-10-2018 AFK25_02255 7b2e7c62f2330a42f2e8001f11ae979c 134 Pfam PF01381 Helix-turn-helix 6 60 2.0E-19 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFK25_02255 7b2e7c62f2330a42f2e8001f11ae979c 134 SUPERFAMILY SSF47413 2 69 9.85E-21 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFK25_02255 7b2e7c62f2330a42f2e8001f11ae979c 134 SMART SM00530 5 60 3.8E-20 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFK25_06750 0b3bd9410b82718e9658445882e9001c 319 Gene3D G3DSA:3.20.20.140 11 318 3.0E-108 T 11-10-2018 AFK25_06750 0b3bd9410b82718e9658445882e9001c 319 SUPERFAMILY SSF51556 14 315 1.63E-75 T 11-10-2018 IPR032466 Metal-dependent hydrolase AFK25_06750 0b3bd9410b82718e9658445882e9001c 319 Pfam PF01244 Membrane dipeptidase (Peptidase family M19) 15 315 1.5E-96 T 11-10-2018 IPR008257 Peptidase M19 GO:0006508|GO:0016805 MetaCyc: PWY-7533|Reactome: R-HSA-2142691|Reactome: R-HSA-5423646 AFK25_08545 c9cb9819e6d91ca649fce6a9e68e13bf 253 Gene3D G3DSA:1.10.287.510 1 93 7.6E-7 T 11-10-2018 AFK25_06135 1a0e6d2896c11eb2ea9f1f716a86791e 135 SUPERFAMILY SSF81593 19 131 2.12E-5 T 11-10-2018 AFK25_06135 1a0e6d2896c11eb2ea9f1f716a86791e 135 Pfam PF01934 Protein of unknown function DUF86 18 131 5.6E-24 T 11-10-2018 IPR008201 Protein of unknown function DUF86 AFK25_06135 1a0e6d2896c11eb2ea9f1f716a86791e 135 Gene3D G3DSA:1.20.120.580 2 134 3.5E-16 T 11-10-2018 IPR037038 Bsu32300-like superfamily AFK25_10550 e21de615b49fc895e96c8f0894808de0 165 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 3 158 1.4E-23 T 11-10-2018 IPR013343 CRISPR-associated protein Cas4 AFK25_10550 e21de615b49fc895e96c8f0894808de0 165 Gene3D G3DSA:3.90.320.10 1 161 5.0E-7 T 11-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal AFK25_10550 e21de615b49fc895e96c8f0894808de0 165 Pfam PF01930 Domain of unknown function DUF83 4 159 3.5E-52 T 11-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 AFK25_12510 69dbeb1f085adae9e7aea67942e021ab 388 Pfam PF00155 Aminotransferase class I and II 32 380 4.0E-67 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFK25_12510 69dbeb1f085adae9e7aea67942e021ab 388 Gene3D G3DSA:3.40.640.10 63 284 1.8E-131 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_12510 69dbeb1f085adae9e7aea67942e021ab 388 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 234 247 - T 11-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AFK25_12510 69dbeb1f085adae9e7aea67942e021ab 388 Gene3D G3DSA:3.90.1150.10 27 381 1.8E-131 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_12510 69dbeb1f085adae9e7aea67942e021ab 388 SUPERFAMILY SSF53383 7 387 8.64E-120 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_07705 902822a79143e520943067af3c93900d 157 SUPERFAMILY SSF49503 58 156 8.75E-28 T 11-10-2018 IPR008972 Cupredoxin AFK25_07705 902822a79143e520943067af3c93900d 157 Gene3D G3DSA:2.60.40.420 25 154 6.7E-33 T 11-10-2018 IPR008972 Cupredoxin AFK25_07705 902822a79143e520943067af3c93900d 157 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 100 148 - T 11-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_07705 902822a79143e520943067af3c93900d 157 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 79 155 8.7E-10 T 11-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_07815 d7ef0e6baf2b4e234ee475426d39df4f 233 SMART SM00382 26 202 2.3E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_07815 d7ef0e6baf2b4e234ee475426d39df4f 233 SUPERFAMILY SSF52540 2 224 3.66E-57 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_07815 d7ef0e6baf2b4e234ee475426d39df4f 233 Gene3D G3DSA:3.40.50.300 1 230 4.2E-57 T 11-10-2018 AFK25_07815 d7ef0e6baf2b4e234ee475426d39df4f 233 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_07815 d7ef0e6baf2b4e234ee475426d39df4f 233 Pfam PF00005 ABC transporter 18 154 1.8E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_07425 7929679606b0923ec9473e79199d1eba 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 159 178 1.2E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_07425 7929679606b0923ec9473e79199d1eba 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 86 97 1.2E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_07425 7929679606b0923ec9473e79199d1eba 285 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 139 147 1.2E-12 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_07425 7929679606b0923ec9473e79199d1eba 285 SUPERFAMILY SSF51735 9 280 1.76E-69 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_07425 7929679606b0923ec9473e79199d1eba 285 Pfam PF00106 short chain dehydrogenase 10 198 2.0E-56 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_07425 7929679606b0923ec9473e79199d1eba 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 159 178 1.1E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_07425 7929679606b0923ec9473e79199d1eba 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 86 97 1.1E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_07425 7929679606b0923ec9473e79199d1eba 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 180 197 1.1E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_07425 7929679606b0923ec9473e79199d1eba 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 10 27 1.1E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_07425 7929679606b0923ec9473e79199d1eba 285 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 133 149 1.1E-25 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_07425 7929679606b0923ec9473e79199d1eba 285 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 9 190 0.0043 T 11-10-2018 AFK25_07425 7929679606b0923ec9473e79199d1eba 285 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 146 174 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFK25_07425 7929679606b0923ec9473e79199d1eba 285 Gene3D G3DSA:3.40.50.720 10 268 4.7E-74 T 11-10-2018 AFK25_03965 f6804b4dcffa25a44ac858e75df7e4dc 132 Pfam PF13411 MerR HTH family regulatory protein 3 69 8.8E-21 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_03965 f6804b4dcffa25a44ac858e75df7e4dc 132 Gene3D G3DSA:1.10.1660.10 1 128 1.2E-37 T 11-10-2018 AFK25_03965 f6804b4dcffa25a44ac858e75df7e4dc 132 TIGRFAM TIGR02051 MerR: Hg(II)-responsive transcriptional regulator 4 129 5.9E-55 T 11-10-2018 IPR011794 Hg(II)-responsive transcriptional regulator GO:0003677|GO:0006355|GO:0045340|GO:0046689 AFK25_03965 f6804b4dcffa25a44ac858e75df7e4dc 132 SMART SM00422 3 72 9.2E-34 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_03965 f6804b4dcffa25a44ac858e75df7e4dc 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 4 15 1.4E-15 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_03965 f6804b4dcffa25a44ac858e75df7e4dc 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 15 28 1.4E-15 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_03965 f6804b4dcffa25a44ac858e75df7e4dc 132 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 39 59 1.4E-15 T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_03965 f6804b4dcffa25a44ac858e75df7e4dc 132 SUPERFAMILY SSF46955 3 129 1.87E-36 T 11-10-2018 IPR009061 Putative DNA-binding domain superfamily AFK25_03965 f6804b4dcffa25a44ac858e75df7e4dc 132 ProSitePatterns PS00552 MerR-type HTH domain signature. 6 28 - T 11-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AFK25_05730 43a48dce29b3eba6a47017b789ad93f2 119 SUPERFAMILY SSF52172 1 118 1.57E-40 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_05730 43a48dce29b3eba6a47017b789ad93f2 119 SMART SM00448 2 114 7.3E-40 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_05730 43a48dce29b3eba6a47017b789ad93f2 119 Pfam PF00072 Response regulator receiver domain 4 115 9.2E-34 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_05730 43a48dce29b3eba6a47017b789ad93f2 119 Gene3D G3DSA:3.40.50.2300 1 119 7.4E-40 T 11-10-2018 AFK25_10965 52653cfdcb4dd089ee7b0f5ff4aa843c 340 TIGRFAM TIGR00904 mreB: cell shape determining protein, MreB/Mrl family 6 333 1.0E-160 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFK25_10965 52653cfdcb4dd089ee7b0f5ff4aa843c 340 Pfam PF06723 MreB/Mbl protein 7 331 8.0E-152 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFK25_10965 52653cfdcb4dd089ee7b0f5ff4aa843c 340 SUPERFAMILY SSF53067 7 144 2.3E-38 T 11-10-2018 AFK25_10965 52653cfdcb4dd089ee7b0f5ff4aa843c 340 Gene3D G3DSA:3.30.420.40 151 314 1.1E-132 T 11-10-2018 AFK25_10965 52653cfdcb4dd089ee7b0f5ff4aa843c 340 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 44 62 9.0E-62 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFK25_10965 52653cfdcb4dd089ee7b0f5ff4aa843c 340 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 64 87 9.0E-62 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFK25_10965 52653cfdcb4dd089ee7b0f5ff4aa843c 340 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 184 204 9.0E-62 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFK25_10965 52653cfdcb4dd089ee7b0f5ff4aa843c 340 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 129 148 9.0E-62 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFK25_10965 52653cfdcb4dd089ee7b0f5ff4aa843c 340 PRINTS PR01652 Bacterial cell shape determinant MreB/Mbl protein signature 297 323 9.0E-62 T 11-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AFK25_10965 52653cfdcb4dd089ee7b0f5ff4aa843c 340 SUPERFAMILY SSF53067 147 329 3.4E-50 T 11-10-2018 AFK25_10965 52653cfdcb4dd089ee7b0f5ff4aa843c 340 Gene3D G3DSA:3.90.640.10 183 256 1.1E-132 T 11-10-2018 AFK25_10965 52653cfdcb4dd089ee7b0f5ff4aa843c 340 Gene3D G3DSA:3.30.420.40 9 324 1.1E-132 T 11-10-2018 AFK25_05665 b3990be61a139fae78c271c988da4fed 528 TIGRFAM TIGR00206 fliF: flagellar M-ring protein FliF 1 527 3.5E-125 T 11-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 AFK25_05665 b3990be61a139fae78c271c988da4fed 528 PIRSF PIRSF004862 1 528 3.2E-112 T 11-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 AFK25_05665 b3990be61a139fae78c271c988da4fed 528 Pfam PF08345 Flagellar M-ring protein C-terminal 257 399 4.6E-24 T 11-10-2018 IPR013556 Flagellar M-ring C-terminal AFK25_05665 b3990be61a139fae78c271c988da4fed 528 Pfam PF01514 Secretory protein of YscJ/FliF family 32 220 5.0E-62 T 11-10-2018 IPR006182 Secretory protein YscJ/FliF AFK25_05665 b3990be61a139fae78c271c988da4fed 528 PRINTS PR01009 Flagellar M-ring protein signature 270 288 7.7E-23 T 11-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 AFK25_05665 b3990be61a139fae78c271c988da4fed 528 PRINTS PR01009 Flagellar M-ring protein signature 154 168 7.7E-23 T 11-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 AFK25_05665 b3990be61a139fae78c271c988da4fed 528 PRINTS PR01009 Flagellar M-ring protein signature 198 216 7.7E-23 T 11-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 AFK25_05665 b3990be61a139fae78c271c988da4fed 528 PRINTS PR01009 Flagellar M-ring protein signature 348 372 7.7E-23 T 11-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 AFK25_05665 b3990be61a139fae78c271c988da4fed 528 PRINTS PR01009 Flagellar M-ring protein signature 122 140 7.7E-23 T 11-10-2018 IPR000067 Flagellar M-ring protein FliF GO:0003774|GO:0009431|GO:0071973 AFK25_05665 b3990be61a139fae78c271c988da4fed 528 Gene3D G3DSA:3.30.300.30 131 220 7.3E-10 T 11-10-2018 AFK25_07695 d5b0bba3f462c231f0006994a8f35225 151 Gene3D G3DSA:3.40.1550.10 4 151 2.2E-37 T 11-10-2018 IPR028976 CheC-like superfamily AFK25_07695 d5b0bba3f462c231f0006994a8f35225 151 Pfam PF13690 Chemotaxis phosphatase CheX 43 122 5.0E-12 T 11-10-2018 IPR028051 Chemotaxis phosphatase CheX-like domain AFK25_07695 d5b0bba3f462c231f0006994a8f35225 151 SUPERFAMILY SSF103039 3 138 4.32E-22 T 11-10-2018 IPR028976 CheC-like superfamily AFK25_02670 7812bd32fcd5732fa7c8a3381c1ef7c2 170 Pfam PF03929 PepSY-associated TM region 6 160 5.4E-15 T 11-10-2018 IPR005625 PepSY-associated TM protein AFK25_06965 fac95c57963c6a36c9479b5c3e876133 92 Pfam PF10819 Protein of unknown function (DUF2564) 16 88 9.6E-16 T 11-10-2018 IPR020314 Uncharacterised protein family YpzA AFK25_06965 fac95c57963c6a36c9479b5c3e876133 92 ProDom PD062992 CYTOSOLIC YPZA BH2151 19 87 1.0E-8 T 11-10-2018 IPR020314 Uncharacterised protein family YpzA AFK25_07210 2dbfe363d67e0ff2f68ff1e4e4ca2d0d 134 Pfam PF13380 CoA binding domain 16 130 3.5E-36 T 11-10-2018 IPR003781 CoA-binding GO:0048037 AFK25_07210 2dbfe363d67e0ff2f68ff1e4e4ca2d0d 134 SMART SM00881 11 104 3.3E-14 T 11-10-2018 IPR003781 CoA-binding GO:0048037 AFK25_07210 2dbfe363d67e0ff2f68ff1e4e4ca2d0d 134 Gene3D G3DSA:3.40.50.720 1 134 7.8E-38 T 11-10-2018 AFK25_07210 2dbfe363d67e0ff2f68ff1e4e4ca2d0d 134 SUPERFAMILY SSF51735 6 132 1.69E-38 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_13765 8694dafe3c0ad4d76539ba684b7a623a 231 SUPERFAMILY SSF143842 36 228 1.57E-43 T 11-10-2018 IPR036209 YwmB-like superfamily AFK25_13765 8694dafe3c0ad4d76539ba684b7a623a 231 Gene3D G3DSA:3.30.2030.10 30 155 3.3E-16 T 11-10-2018 AFK25_13765 8694dafe3c0ad4d76539ba684b7a623a 231 Gene3D G3DSA:3.30.360.40 157 231 4.1E-31 T 11-10-2018 AFK25_13765 8694dafe3c0ad4d76539ba684b7a623a 231 Pfam PF08680 TATA-box binding 49 231 1.5E-53 T 11-10-2018 IPR014794 TATA-box binding AFK25_09585 5876d9ce5a5d5ee0777435e5a789621a 171 Gene3D G3DSA:1.10.3820.10 3 157 1.5E-42 T 11-10-2018 IPR038266 NapC/NirT cytochrome c superfamily AFK25_09585 5876d9ce5a5d5ee0777435e5a789621a 171 SUPERFAMILY SSF48695 11 147 1.77E-23 T 11-10-2018 IPR036280 Multiheme cytochrome superfamily AFK25_09585 5876d9ce5a5d5ee0777435e5a789621a 171 Pfam PF03264 NapC/NirT cytochrome c family, N-terminal region 12 146 6.3E-14 T 11-10-2018 IPR005126 NapC/NirT cytochrome c, N-terminal AFK25_06690 a76824d2d0998cb7487a16133e5c4660 425 Gene3D G3DSA:3.30.830.10 3 230 9.5E-61 T 11-10-2018 AFK25_06690 a76824d2d0998cb7487a16133e5c4660 425 Pfam PF05193 Peptidase M16 inactive domain 182 354 1.9E-21 T 11-10-2018 IPR007863 Peptidase M16, C-terminal AFK25_06690 a76824d2d0998cb7487a16133e5c4660 425 SUPERFAMILY SSF63411 245 411 8.0E-32 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFK25_06690 a76824d2d0998cb7487a16133e5c4660 425 Gene3D G3DSA:3.30.830.10 238 424 1.2E-44 T 11-10-2018 AFK25_06690 a76824d2d0998cb7487a16133e5c4660 425 SUPERFAMILY SSF63411 10 232 3.3E-21 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFK25_05675 54aea3074dd76e642e294e349f2217e9 259 Pfam PF02108 Flagellar assembly protein FliH 118 246 2.3E-17 T 11-10-2018 IPR018035 Flagellar assembly protein FliH/Type III secretion system HrpE AFK25_05675 54aea3074dd76e642e294e349f2217e9 259 TIGRFAM TIGR03825 FliH_bacil: flagellar assembly protein FliH 4 258 1.1E-81 T 11-10-2018 IPR022524 Flagellar assembly FliH, Bacilli AFK25_04415 68afc684cfa8c2db6326429baed4a778 178 Hamap MF_01682 Acireductone dioxygenase [mtnD]. 1 176 29.525 T 11-10-2018 IPR023956 Acireductone dioxygenase ARD, bacteria GO:0005506|GO:0010308|GO:0010309|GO:0016151|GO:0019284|GO:0055114 KEGG: 00270+1.13.11.54+1.13.11.53|MetaCyc: PWY-4361|MetaCyc: PWY-5389 AFK25_04415 68afc684cfa8c2db6326429baed4a778 178 Gene3D G3DSA:2.60.120.10 1 171 6.1E-54 T 11-10-2018 IPR014710 RmlC-like jelly roll fold AFK25_04415 68afc684cfa8c2db6326429baed4a778 178 SUPERFAMILY SSF51182 13 174 7.54E-32 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily AFK25_04415 68afc684cfa8c2db6326429baed4a778 178 Pfam PF03079 ARD/ARD' family 9 169 4.2E-34 T 11-10-2018 IPR004313 Acireductone dioxygenase ARD family GO:0010309|GO:0055114 KEGG: 00270+1.13.11.54|MetaCyc: PWY-4361|Reactome: R-HSA-1237112 AFK25_00530 0feebecb0c67761ac728013454ca2337 60 ProSitePatterns PS01067 Protein secE/sec61-gamma signature. 7 35 - T 11-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFK25_00530 0feebecb0c67761ac728013454ca2337 60 Hamap MF_00422 Protein translocase subunit SecE [secE]. 2 57 13.836 T 11-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFK25_00530 0feebecb0c67761ac728013454ca2337 60 TIGRFAM TIGR00964 secE_bact: preprotein translocase, SecE subunit 5 59 1.7E-23 T 11-10-2018 IPR005807 SecE subunit of protein translocation complex, bacterial-like GO:0009306|GO:0015450|GO:0016021 AFK25_00530 0feebecb0c67761ac728013454ca2337 60 Gene3D G3DSA:1.20.5.1030 1 58 9.7E-21 T 11-10-2018 IPR038379 SecE superfamily AFK25_00530 0feebecb0c67761ac728013454ca2337 60 Pfam PF00584 SecE/Sec61-gamma subunits of protein translocation complex 6 58 2.0E-22 T 11-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AFK25_07975 b34eeb6ebf0c4ba6f661c79b8b393fed 328 Pfam PF13407 Periplasmic binding protein domain 53 304 4.3E-60 T 11-10-2018 IPR025997 Periplasmic binding protein AFK25_07975 b34eeb6ebf0c4ba6f661c79b8b393fed 328 SUPERFAMILY SSF53822 51 324 3.87E-68 T 11-10-2018 IPR028082 Periplasmic binding protein-like I AFK25_07975 b34eeb6ebf0c4ba6f661c79b8b393fed 328 Gene3D G3DSA:3.40.50.2300 60 314 3.0E-74 T 11-10-2018 AFK25_07975 b34eeb6ebf0c4ba6f661c79b8b393fed 328 Gene3D G3DSA:3.40.50.2300 152 322 3.0E-74 T 11-10-2018 AFK25_07050 9fd18db5cccacb385582f84d7121b1da 158 SUPERFAMILY SSF89562 2 156 2.09E-46 T 11-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily AFK25_07050 9fd18db5cccacb385582f84d7121b1da 158 TIGRFAM TIGR01935 NOT-MenG: RraA family 3 152 8.7E-55 T 11-10-2018 IPR010203 Regulator of ribonuclease activity A GO:0008428|GO:0051252 AFK25_07050 9fd18db5cccacb385582f84d7121b1da 158 Gene3D G3DSA:3.50.30.40 1 158 5.9E-61 T 11-10-2018 AFK25_07050 9fd18db5cccacb385582f84d7121b1da 158 Pfam PF03737 Aldolase/RraA 3 151 1.0E-40 T 11-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein AFK25_10090 96e39782f71bb2d6ce02700c65cb6ef4 481 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 14 472 7.8E-160 T 11-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 AFK25_10090 96e39782f71bb2d6ce02700c65cb6ef4 481 PIRSF PIRSF005690 1 481 1.2E-133 T 11-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 AFK25_13245 5bcee7f69a82eb88d7f7cbaa5fb984f1 514 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 451 507 8.8E-14 T 11-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain AFK25_13245 5bcee7f69a82eb88d7f7cbaa5fb984f1 514 Pfam PF00460 Flagella basal body rod protein 8 35 7.8E-5 T 11-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 AFK25_13245 5bcee7f69a82eb88d7f7cbaa5fb984f1 514 SUPERFAMILY SSF64518 158 507 2.75E-24 T 11-10-2018 AFK25_13245 5bcee7f69a82eb88d7f7cbaa5fb984f1 514 TIGRFAM TIGR02492 flgK_ends: flagellar hook-associated protein FlgK 7 507 7.2E-117 T 11-10-2018 IPR002371 Flagellar hook-associated protein 1 GO:0005198|GO:0009424|GO:0044780 AFK25_09465 200179dc6d07fede2e4d9b38bcd39605 304 Pfam PF00248 Aldo/keto reductase family 15 294 1.4E-67 T 11-10-2018 IPR023210 NADP-dependent oxidoreductase domain AFK25_09465 200179dc6d07fede2e4d9b38bcd39605 304 PRINTS PR00069 Aldo-keto reductase signature 103 121 2.5E-6 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFK25_09465 200179dc6d07fede2e4d9b38bcd39605 304 PRINTS PR00069 Aldo-keto reductase signature 134 151 2.5E-6 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFK25_09465 200179dc6d07fede2e4d9b38bcd39605 304 PRINTS PR00069 Aldo-keto reductase signature 37 61 2.5E-6 T 11-10-2018 IPR020471 Aldo/keto reductase GO:0016491|GO:0055114 AFK25_09465 200179dc6d07fede2e4d9b38bcd39605 304 SUPERFAMILY SSF51430 1 299 9.69E-85 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFK25_09465 200179dc6d07fede2e4d9b38bcd39605 304 Gene3D G3DSA:3.20.20.100 1 296 8.2E-108 T 11-10-2018 IPR036812 NADP-dependent oxidoreductase domain superfamily AFK25_11225 f1d9226a6b23788a16c5305d6ebb1890 265 Gene3D G3DSA:3.40.50.1860 5 253 3.6E-102 T 11-10-2018 AFK25_11225 f1d9226a6b23788a16c5305d6ebb1890 265 SUPERFAMILY SSF53681 109 262 4.74E-43 T 11-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFK25_11225 f1d9226a6b23788a16c5305d6ebb1890 265 TIGRFAM TIGR00067 glut_race: glutamate racemase 5 253 2.9E-92 T 11-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFK25_11225 f1d9226a6b23788a16c5305d6ebb1890 265 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 69 77 - T 11-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFK25_11225 f1d9226a6b23788a16c5305d6ebb1890 265 Hamap MF_00258 Glutamate racemase [murI]. 3 255 42.022 T 11-10-2018 IPR004391 Glutamate racemase GO:0008881|GO:0009252 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFK25_11225 f1d9226a6b23788a16c5305d6ebb1890 265 SUPERFAMILY SSF53681 4 106 1.9E-37 T 11-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFK25_11225 f1d9226a6b23788a16c5305d6ebb1890 265 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 179 189 - T 11-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFK25_11225 f1d9226a6b23788a16c5305d6ebb1890 265 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 214 1.8E-41 T 11-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AFK25_11225 f1d9226a6b23788a16c5305d6ebb1890 265 Gene3D G3DSA:3.40.50.1860 94 206 3.6E-102 T 11-10-2018 AFK25_07110 2d69383f84e2109ba5c15cbc9adba5b2 573 SUPERFAMILY SSF56762 1 558 1.14E-174 T 11-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_07110 2d69383f84e2109ba5c15cbc9adba5b2 573 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 549 558 - T 11-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 AFK25_07110 2d69383f84e2109ba5c15cbc9adba5b2 573 ProSitePatterns PS00507 Nickel-dependent hydrogenases large subunit signature 1. 40 65 - T 11-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 AFK25_07110 2d69383f84e2109ba5c15cbc9adba5b2 573 Pfam PF00374 Nickel-dependent hydrogenase 40 558 2.0E-226 T 11-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 AFK25_07110 2d69383f84e2109ba5c15cbc9adba5b2 573 Gene3D G3DSA:1.10.645.10 1 558 1.1E-245 T 11-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13890 b44843e0f0b71f6a2af556739d4b840f 411 Gene3D G3DSA:3.90.1150.10 6 390 6.7E-193 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_13890 b44843e0f0b71f6a2af556739d4b840f 411 Gene3D G3DSA:3.40.640.10 33 283 6.7E-193 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_13890 b44843e0f0b71f6a2af556739d4b840f 411 PIRSF PIRSF000412 1 409 2.0E-177 T 11-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFK25_13890 b44843e0f0b71f6a2af556739d4b840f 411 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 218 234 - T 11-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFK25_13890 b44843e0f0b71f6a2af556739d4b840f 411 Pfam PF00464 Serine hydroxymethyltransferase 4 380 3.2E-186 T 11-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFK25_13890 b44843e0f0b71f6a2af556739d4b840f 411 SUPERFAMILY SSF53383 2 410 6.19E-187 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_13890 b44843e0f0b71f6a2af556739d4b840f 411 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 3 411 54.708 T 11-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AFK25_12755 ad07803ab13d7fc21011495dbf25c05f 222 Gene3D G3DSA:1.10.3720.10 9 222 2.7E-48 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_12755 ad07803ab13d7fc21011495dbf25c05f 222 SUPERFAMILY SSF161098 11 210 2.88E-47 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_12755 ad07803ab13d7fc21011495dbf25c05f 222 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 44 219 6.2E-23 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_13550 a3c7d5313e4bbfdbc1e72a214830065e 167 SUPERFAMILY SSF63817 34 165 5.23E-35 T 11-10-2018 IPR023365 Sortase domain superfamily AFK25_13550 a3c7d5313e4bbfdbc1e72a214830065e 167 TIGRFAM TIGR01076 sortase_fam: sortase 45 165 5.3E-26 T 11-10-2018 IPR005754 Sortase family AFK25_13550 a3c7d5313e4bbfdbc1e72a214830065e 167 Pfam PF04203 Sortase family 48 165 7.7E-26 T 11-10-2018 IPR005754 Sortase family AFK25_13550 a3c7d5313e4bbfdbc1e72a214830065e 167 Gene3D G3DSA:2.40.260.10 30 166 2.5E-38 T 11-10-2018 IPR023365 Sortase domain superfamily AFK25_02625 9192d5255ac64bf2ac22081a54e39ef7 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 128 136 3.6E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_02625 9192d5255ac64bf2ac22081a54e39ef7 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 148 167 3.6E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_02625 9192d5255ac64bf2ac22081a54e39ef7 235 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 75 86 3.6E-11 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_02625 9192d5255ac64bf2ac22081a54e39ef7 235 Pfam PF00106 short chain dehydrogenase 5 188 5.3E-59 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_02625 9192d5255ac64bf2ac22081a54e39ef7 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 122 138 2.2E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_02625 9192d5255ac64bf2ac22081a54e39ef7 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 169 186 2.2E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_02625 9192d5255ac64bf2ac22081a54e39ef7 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 148 167 2.2E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_02625 9192d5255ac64bf2ac22081a54e39ef7 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 194 214 2.2E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_02625 9192d5255ac64bf2ac22081a54e39ef7 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 75 86 2.2E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_02625 9192d5255ac64bf2ac22081a54e39ef7 235 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 6 23 2.2E-34 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_02625 9192d5255ac64bf2ac22081a54e39ef7 235 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 135 163 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFK25_02625 9192d5255ac64bf2ac22081a54e39ef7 235 Gene3D G3DSA:3.40.50.720 1 233 1.1E-70 T 11-10-2018 AFK25_02625 9192d5255ac64bf2ac22081a54e39ef7 235 SUPERFAMILY SSF51735 2 216 1.35E-67 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_11860 00691266e223009a963d9ca00ee1854d 210 PIRSF PIRSF021278 2 210 1.7E-88 T 11-10-2018 IPR024699 Acetoin utilization protein AcuA GO:0019152|GO:0045150 AFK25_11860 00691266e223009a963d9ca00ee1854d 210 Gene3D G3DSA:3.40.630.30 1 210 5.8E-94 T 11-10-2018 AFK25_11860 00691266e223009a963d9ca00ee1854d 210 SUPERFAMILY SSF55729 33 121 9.26E-10 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFK25_11860 00691266e223009a963d9ca00ee1854d 210 Pfam PF00583 Acetyltransferase (GNAT) family 45 121 1.6E-6 T 11-10-2018 IPR000182 GNAT domain AFK25_13800 8c408c3358aee54e96c30f3ded874dae 139 Pfam PF12838 4Fe-4S dicluster domain 45 102 1.7E-10 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFK25_13800 8c408c3358aee54e96c30f3ded874dae 139 SUPERFAMILY SSF54862 24 125 6.7E-25 T 11-10-2018 AFK25_13800 8c408c3358aee54e96c30f3ded874dae 139 Hamap MF_01351 NAD(P)H-quinone oxidoreductase subunit I, chloroplastic [ndhI]. 1 135 22.549 T 11-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13800 8c408c3358aee54e96c30f3ded874dae 139 TIGRFAM TIGR01971 NuoI: NADH-quinone oxidoreductase, chain I 7 122 2.2E-35 T 11-10-2018 IPR010226 NADH-quinone oxidoreductase, chain I GO:0016020|GO:0016651|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13800 8c408c3358aee54e96c30f3ded874dae 139 Gene3D G3DSA:3.30.70.3270 24 138 5.4E-33 T 11-10-2018 AFK25_13800 8c408c3358aee54e96c30f3ded874dae 139 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 88 99 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFK25_13180 c5bad4b44f339547771873853dfeeec7 237 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 195 7.7E-28 T 11-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 AFK25_13180 c5bad4b44f339547771873853dfeeec7 237 Gene3D G3DSA:3.60.21.10 1 232 1.1E-53 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like AFK25_13180 c5bad4b44f339547771873853dfeeec7 237 SUPERFAMILY SSF56300 1 222 1.55E-50 T 11-10-2018 AFK25_13180 c5bad4b44f339547771873853dfeeec7 237 PIRSF PIRSF000883 1 236 5.6E-52 T 11-10-2018 IPR011152 Phosphoesterase MJ0912 AFK25_09970 306061231612b7329c76c7c36228b32b 482 SUPERFAMILY SSF53383 9 481 1.71E-119 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_09970 306061231612b7329c76c7c36228b32b 482 Gene3D G3DSA:3.40.640.10 85 325 1.7E-60 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_09970 306061231612b7329c76c7c36228b32b 482 Hamap MF_00713 Probable glycine dehydrogenase (decarboxylating) subunit 2 [gcvPB]. 6 482 60.625 T 11-10-2018 IPR023012 Probable glycine dehydrogenase (decarboxylating) subunit 2 GO:0004375|GO:0019464 KEGG: 00260+1.4.4.2 AFK25_09970 306061231612b7329c76c7c36228b32b 482 Gene3D G3DSA:3.90.1150.10 337 469 1.6E-50 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_09970 306061231612b7329c76c7c36228b32b 482 Pfam PF02347 Glycine cleavage system P-protein 33 295 2.1E-11 T 11-10-2018 IPR020581 Glycine cleavage system P protein GO:0004375|GO:0006546|GO:0055114 KEGG: 00260+1.4.4.2|Reactome: R-HSA-6783984 AFK25_13645 f9741e43053794f2486f8d97939dbdcf 322 Gene3D G3DSA:3.90.25.10 183 318 4.9E-129 T 11-10-2018 AFK25_13645 f9741e43053794f2486f8d97939dbdcf 322 Pfam PF16363 GDP-mannose 4,6 dehydratase 3 312 3.6E-59 T 11-10-2018 IPR016040 NAD(P)-binding domain AFK25_13645 f9741e43053794f2486f8d97939dbdcf 322 TIGRFAM TIGR01179 galE: UDP-glucose 4-epimerase GalE 1 321 2.6E-136 T 11-10-2018 IPR005886 UDP-glucose 4-epimerase GO:0003978|GO:0006012 KEGG: 00052+5.1.3.2|KEGG: 00520+5.1.3.2|MetaCyc: PWY-3821|MetaCyc: PWY-6317|MetaCyc: PWY-6397|MetaCyc: PWY-6527|MetaCyc: PWY-7328|MetaCyc: PWY-7344|Reactome: R-HSA-5609977|Reactome: R-HSA-70370 AFK25_13645 f9741e43053794f2486f8d97939dbdcf 322 SUPERFAMILY SSF51735 2 321 2.28E-99 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_13645 f9741e43053794f2486f8d97939dbdcf 322 Gene3D G3DSA:3.40.50.720 2 263 4.9E-129 T 11-10-2018 AFK25_10190 c6841c8d018766c10e50176640ea2a99 580 Pfam PF00672 HAMP domain 224 269 1.8E-8 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_10190 c6841c8d018766c10e50176640ea2a99 580 SUPERFAMILY SSF58104 243 579 2.88E-58 T 11-10-2018 AFK25_10190 c6841c8d018766c10e50176640ea2a99 580 SMART SM00304 222 275 6.6E-9 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_10190 c6841c8d018766c10e50176640ea2a99 580 Gene3D G3DSA:1.10.287.950 274 579 3.3E-56 T 11-10-2018 AFK25_10190 c6841c8d018766c10e50176640ea2a99 580 Gene3D G3DSA:1.10.8.500 222 273 2.7E-8 T 11-10-2018 AFK25_10190 c6841c8d018766c10e50176640ea2a99 580 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 378 515 8.4E-33 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_10190 c6841c8d018766c10e50176640ea2a99 580 SMART SM00283 311 579 1.1E-35 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_10190 c6841c8d018766c10e50176640ea2a99 580 Gene3D G3DSA:3.30.450.20 83 203 7.9E-6 T 11-10-2018 AFK25_08465 ed8b9d210783bf9f55d5bb1333c34af9 234 SUPERFAMILY SSF88713 25 227 2.04E-72 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFK25_08465 ed8b9d210783bf9f55d5bb1333c34af9 234 Gene3D G3DSA:3.20.20.370 18 231 2.5E-79 T 11-10-2018 AFK25_08465 ed8b9d210783bf9f55d5bb1333c34af9 234 Pfam PF01522 Polysaccharide deacetylase 30 151 8.9E-39 T 11-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFK25_02250 4307647bfa35655427853ff1c937bfe6 516 SUPERFAMILY SSF52980 390 506 2.04E-20 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFK25_02250 4307647bfa35655427853ff1c937bfe6 516 Gene3D G3DSA:3.40.91.100 365 515 7.3E-14 T 11-10-2018 AFK25_02250 4307647bfa35655427853ff1c937bfe6 516 Pfam PF04471 Restriction endonuclease 386 501 5.0E-31 T 11-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 AFK25_03855 25022888e278aac438e2dbb7e102d436 533 Pfam PF03237 Terminase-like family 56 279 7.7E-5 T 11-10-2018 IPR004921 Terminase large subunit, T4likevirus-type AFK25_03855 25022888e278aac438e2dbb7e102d436 533 Gene3D G3DSA:3.40.50.300 1 217 8.4E-52 T 11-10-2018 AFK25_03855 25022888e278aac438e2dbb7e102d436 533 Gene3D G3DSA:3.30.420.240 328 533 2.2E-57 T 11-10-2018 AFK25_14335 66b8a661d251ec8cfa62ba5cb4cf8716 208 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_14335 66b8a661d251ec8cfa62ba5cb4cf8716 208 Pfam PF00005 ABC transporter 17 157 1.3E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_14335 66b8a661d251ec8cfa62ba5cb4cf8716 208 SMART SM00382 26 207 2.4E-13 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_14335 66b8a661d251ec8cfa62ba5cb4cf8716 208 SUPERFAMILY SSF52540 2 206 4.34E-49 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_14335 66b8a661d251ec8cfa62ba5cb4cf8716 208 Gene3D G3DSA:3.40.50.300 1 207 1.2E-50 T 11-10-2018 AFK25_09140 c330fa8b9c1dec23732f9ebd7a828523 166 Pfam PF00719 Inorganic pyrophosphatase 11 162 8.7E-56 T 11-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 AFK25_09140 c330fa8b9c1dec23732f9ebd7a828523 166 ProSitePatterns PS00387 Inorganic pyrophosphatase signature. 57 63 - T 11-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 AFK25_09140 c330fa8b9c1dec23732f9ebd7a828523 166 Hamap MF_00209 Inorganic pyrophosphatase [ppa]. 6 162 36.05 T 11-10-2018 IPR008162 Inorganic pyrophosphatase GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 AFK25_09140 c330fa8b9c1dec23732f9ebd7a828523 166 SUPERFAMILY SSF50324 4 163 6.28E-63 T 11-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 AFK25_09140 c330fa8b9c1dec23732f9ebd7a828523 166 Gene3D G3DSA:3.90.80.10 2 166 1.7E-63 T 11-10-2018 IPR036649 Inorganic pyrophosphatase superfamily GO:0000287|GO:0004427|GO:0005737|GO:0006796 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807|Reactome: R-HSA-71737 AFK25_10495 59cbd11ca0d3875dd8428b2503b6389b 170 TIGRFAM TIGR01668 YqeG_hyp_ppase: HAD phosphatase, family IIIA 3 165 5.0E-56 T 11-10-2018 IPR010021 HAD-superfamily phosphatase, YqeG-like AFK25_10495 59cbd11ca0d3875dd8428b2503b6389b 170 SUPERFAMILY SSF56784 11 138 7.34E-26 T 11-10-2018 IPR036412 HAD-like superfamily AFK25_10495 59cbd11ca0d3875dd8428b2503b6389b 170 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 34 136 9.4E-9 T 11-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AFK25_10495 59cbd11ca0d3875dd8428b2503b6389b 170 Pfam PF13419 Haloacid dehalogenase-like hydrolase 43 136 1.7E-11 T 11-10-2018 AFK25_10495 59cbd11ca0d3875dd8428b2503b6389b 170 TIGRFAM TIGR01662 HAD-SF-IIIA: HAD hydrolase, family IIIA 28 138 1.2E-24 T 11-10-2018 IPR006549 HAD-superfamily hydrolase,subfamily IIIA Reactome: R-HSA-5649702 AFK25_10495 59cbd11ca0d3875dd8428b2503b6389b 170 Gene3D G3DSA:3.40.50.1000 16 152 1.6E-24 T 11-10-2018 IPR023214 HAD superfamily AFK25_11705 a40d72c6f6cfd9fc560e60871e2b2e98 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 3.1E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_11705 a40d72c6f6cfd9fc560e60871e2b2e98 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 78 89 3.1E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_11705 a40d72c6f6cfd9fc560e60871e2b2e98 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 3.1E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_11705 a40d72c6f6cfd9fc560e60871e2b2e98 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.1E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_11705 a40d72c6f6cfd9fc560e60871e2b2e98 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 127 143 3.1E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_11705 a40d72c6f6cfd9fc560e60871e2b2e98 253 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 3.1E-28 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_11705 a40d72c6f6cfd9fc560e60871e2b2e98 253 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 11 245 7.0E-48 T 11-10-2018 AFK25_11705 a40d72c6f6cfd9fc560e60871e2b2e98 253 SUPERFAMILY SSF51735 2 245 2.18E-64 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_11705 a40d72c6f6cfd9fc560e60871e2b2e98 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 2.4E-5 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_11705 a40d72c6f6cfd9fc560e60871e2b2e98 253 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 78 89 2.4E-5 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_11705 a40d72c6f6cfd9fc560e60871e2b2e98 253 Gene3D G3DSA:3.40.50.720 1 253 5.4E-70 T 11-10-2018 AFK25_02560 257de4b18086dbc5bf272e6f12c54e6d 131 Pfam PF13686 DsrE/DsrF/DrsH-like family 60 129 3.8E-22 T 11-10-2018 IPR032836 DsrE2-like family AFK25_02560 257de4b18086dbc5bf272e6f12c54e6d 131 Pfam PF13686 DsrE/DsrF/DrsH-like family 2 54 1.7E-11 T 11-10-2018 IPR032836 DsrE2-like family AFK25_02560 257de4b18086dbc5bf272e6f12c54e6d 131 Gene3D G3DSA:3.40.1260.10 1 131 1.3E-36 T 11-10-2018 IPR027396 DsrEFH-like AFK25_02560 257de4b18086dbc5bf272e6f12c54e6d 131 SUPERFAMILY SSF75169 3 131 5.38E-23 T 11-10-2018 IPR027396 DsrEFH-like AFK25_09440 649978ab60229f7b71e45a367efb89be 298 TIGRFAM TIGR02225 recomb_XerD: tyrosine recombinase XerD 7 298 6.8E-126 T 11-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 AFK25_09440 649978ab60229f7b71e45a367efb89be 298 Gene3D G3DSA:1.10.150.130 2 99 4.3E-26 T 11-10-2018 IPR010998 Integrase/recombinase, N-terminal AFK25_09440 649978ab60229f7b71e45a367efb89be 298 Pfam PF00589 Phage integrase family 111 284 1.3E-56 T 11-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AFK25_09440 649978ab60229f7b71e45a367efb89be 298 Pfam PF02899 Phage integrase, N-terminal SAM-like domain 6 89 8.0E-24 T 11-10-2018 IPR004107 Integrase, SAM-like, N-terminal GO:0003677|GO:0015074 AFK25_09440 649978ab60229f7b71e45a367efb89be 298 Hamap MF_01807 Tyrosine recombinase XerD [xerD]. 1 298 62.897 T 11-10-2018 IPR011932 Tyrosine recombinase XerD GO:0006310|GO:0009009 AFK25_09440 649978ab60229f7b71e45a367efb89be 298 Gene3D G3DSA:1.10.443.10 110 292 3.8E-71 T 11-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AFK25_09440 649978ab60229f7b71e45a367efb89be 298 SUPERFAMILY SSF56349 4 291 2.59E-64 T 11-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AFK25_09440 649978ab60229f7b71e45a367efb89be 298 TIGRFAM TIGR02224 recomb_XerC: tyrosine recombinase XerC 6 298 1.6E-104 T 11-10-2018 IPR011931 Tyrosine recombinase XerC GO:0003677|GO:0006310|GO:0007059|GO:0015074|GO:0051301 AFK25_09440 649978ab60229f7b71e45a367efb89be 298 Hamap MF_01808 Tyrosine recombinase XerC [xerC]. 3 298 59.014 T 11-10-2018 IPR023009 Tyrosine recombinase XerC/XerD AFK25_03335 2da464e2d1971d6961cad0cfc7075c7f 287 SUPERFAMILY SSF82549 1 283 2.88E-93 T 11-10-2018 AFK25_03335 2da464e2d1971d6961cad0cfc7075c7f 287 Pfam PF02645 Uncharacterised protein, DegV family COG1307 3 282 6.7E-88 T 11-10-2018 IPR003797 DegV AFK25_03335 2da464e2d1971d6961cad0cfc7075c7f 287 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 3 280 2.0E-98 T 11-10-2018 IPR003797 DegV AFK25_03335 2da464e2d1971d6961cad0cfc7075c7f 287 Gene3D G3DSA:3.30.1180.10 156 287 2.0E-52 T 11-10-2018 AFK25_03335 2da464e2d1971d6961cad0cfc7075c7f 287 Gene3D G3DSA:3.40.50.10170 1 153 1.3E-49 T 11-10-2018 AFK25_02920 ecc42ad85c0705a02095f79616ca078a 569 Pfam PF16657 Maltogenic Amylase, C-terminal domain 490 564 1.2E-9 T 11-10-2018 IPR032091 Maltogenic Amylase, C-terminal AFK25_02920 ecc42ad85c0705a02095f79616ca078a 569 Gene3D G3DSA:3.90.400.10 110 179 1.1E-210 T 11-10-2018 AFK25_02920 ecc42ad85c0705a02095f79616ca078a 569 SUPERFAMILY SSF51445 8 487 1.02E-162 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily AFK25_02920 ecc42ad85c0705a02095f79616ca078a 569 SUPERFAMILY SSF51011 490 568 1.97E-20 T 11-10-2018 AFK25_02920 ecc42ad85c0705a02095f79616ca078a 569 Pfam PF00128 Alpha amylase, catalytic domain 33 386 4.4E-127 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFK25_02920 ecc42ad85c0705a02095f79616ca078a 569 SMART SM00642 18 429 6.2E-175 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFK25_02920 ecc42ad85c0705a02095f79616ca078a 569 Gene3D G3DSA:3.20.20.80 9 482 1.1E-210 T 11-10-2018 AFK25_02920 ecc42ad85c0705a02095f79616ca078a 569 Gene3D G3DSA:2.60.40.1180 491 569 8.4E-26 T 11-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFK25_04850 985bf74640c7f69c7b0af57d4ef7e30e 258 Gene3D G3DSA:3.30.1240.10 81 180 1.8E-89 T 11-10-2018 AFK25_04850 985bf74640c7f69c7b0af57d4ef7e30e 258 Pfam PF08282 haloacid dehalogenase-like hydrolase 6 248 5.4E-61 T 11-10-2018 AFK25_04850 985bf74640c7f69c7b0af57d4ef7e30e 258 TIGRFAM TIGR00099 Cof-subfamily: Cof-like hydrolase 5 248 7.4E-64 T 11-10-2018 IPR000150 Cof family GO:0016787 AFK25_04850 985bf74640c7f69c7b0af57d4ef7e30e 258 ProSitePatterns PS01229 Hypothetical cof family signature 2. 205 227 - T 11-10-2018 AFK25_04850 985bf74640c7f69c7b0af57d4ef7e30e 258 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 5 224 8.8E-23 T 11-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 AFK25_04850 985bf74640c7f69c7b0af57d4ef7e30e 258 Gene3D G3DSA:3.40.50.1000 4 247 1.8E-89 T 11-10-2018 IPR023214 HAD superfamily AFK25_04850 985bf74640c7f69c7b0af57d4ef7e30e 258 SUPERFAMILY SSF56784 1 255 1.65E-68 T 11-10-2018 IPR036412 HAD-like superfamily AFK25_09545 3da17b990f38567a3d6ba02118781417 165 SUPERFAMILY SSF53218 8 163 1.31E-44 T 11-10-2018 IPR036425 MoaB/Mog-like domain superfamily AFK25_09545 3da17b990f38567a3d6ba02118781417 165 Gene3D G3DSA:3.40.980.10 5 164 3.0E-49 T 11-10-2018 IPR036425 MoaB/Mog-like domain superfamily AFK25_09545 3da17b990f38567a3d6ba02118781417 165 Pfam PF00994 Probable molybdopterin binding domain 18 157 1.2E-36 T 11-10-2018 IPR001453 MoaB/Mog domain AFK25_09545 3da17b990f38567a3d6ba02118781417 165 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 14 153 2.6E-38 T 11-10-2018 IPR001453 MoaB/Mog domain AFK25_09545 3da17b990f38567a3d6ba02118781417 165 SMART SM00852 17 158 3.0E-28 T 11-10-2018 IPR001453 MoaB/Mog domain AFK25_09545 3da17b990f38567a3d6ba02118781417 165 PIRSF PIRSF006443 1 165 1.1E-63 T 11-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 AFK25_11490 7acd1f3f8a7ae70042cc63213cbe90d3 268 SUPERFAMILY SSF161098 4 268 4.77E-68 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_11490 7acd1f3f8a7ae70042cc63213cbe90d3 268 Gene3D G3DSA:1.10.3720.10 1 260 2.2E-60 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_11490 7acd1f3f8a7ae70042cc63213cbe90d3 268 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 87 262 1.9E-21 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_04045 72f4fb2cb95a8a87c33c21b9551415ae 244 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 4 200 3.7E-16 T 11-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 AFK25_04045 72f4fb2cb95a8a87c33c21b9551415ae 244 PIRSF PIRSF000883 3 236 7.6E-43 T 11-10-2018 IPR011152 Phosphoesterase MJ0912 AFK25_04045 72f4fb2cb95a8a87c33c21b9551415ae 244 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 4 197 4.7E-26 T 11-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 AFK25_04045 72f4fb2cb95a8a87c33c21b9551415ae 244 Gene3D G3DSA:3.60.21.10 2 239 3.8E-53 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like AFK25_04045 72f4fb2cb95a8a87c33c21b9551415ae 244 SUPERFAMILY SSF56300 4 227 2.36E-44 T 11-10-2018 AFK25_14585 a6eab1de16e9535833f62869623fb9df 163 SUPERFAMILY SSF50249 1 163 2.14E-61 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_14585 a6eab1de16e9535833f62869623fb9df 163 Gene3D G3DSA:2.40.50.140 1 111 5.7E-49 T 11-10-2018 AFK25_14585 a6eab1de16e9535833f62869623fb9df 163 Hamap MF_00984 Single-stranded DNA-binding protein. 2 107 37.916 T 11-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 AFK25_14585 a6eab1de16e9535833f62869623fb9df 163 TIGRFAM TIGR00621 ssb: single-stranded DNA-binding protein 1 163 2.3E-50 T 11-10-2018 IPR011344 Single-stranded DNA-binding protein GO:0003697|GO:0006260 Reactome: R-HSA-2151201 AFK25_14585 a6eab1de16e9535833f62869623fb9df 163 PIRSF PIRSF002070 1 152 4.4E-45 T 11-10-2018 AFK25_14585 a6eab1de16e9535833f62869623fb9df 163 Pfam PF00436 Single-strand binding protein family 2 103 2.4E-40 T 11-10-2018 IPR000424 Primosome PriB/single-strand DNA-binding GO:0003697 Reactome: R-HSA-2151201 AFK25_14195 71e05687c0bd3e7845fa6a718728aad1 398 Pfam PF07690 Major Facilitator Superfamily 19 263 2.4E-35 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFK25_14195 71e05687c0bd3e7845fa6a718728aad1 398 SUPERFAMILY SSF103473 7 397 1.96E-83 T 11-10-2018 IPR036259 MFS transporter superfamily AFK25_14195 71e05687c0bd3e7845fa6a718728aad1 398 ProSitePatterns PS00217 Sugar transport proteins signature 2. 106 131 - T 11-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFK25_14195 71e05687c0bd3e7845fa6a718728aad1 398 Gene3D G3DSA:1.20.1250.20 7 398 8.6E-90 T 11-10-2018 AFK25_05170 0008991c67726e7672bd437a268ace87 297 SUPERFAMILY SSF51735 2 155 2.96E-19 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_05170 0008991c67726e7672bd437a268ace87 297 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 171 290 1.2E-31 T 11-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain AFK25_05170 0008991c67726e7672bd437a268ace87 297 SUPERFAMILY SSF48179 170 290 9.86E-29 T 11-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AFK25_05170 0008991c67726e7672bd437a268ace87 297 Pfam PF02558 Ketopantoate reductase PanE/ApbA 3 146 7.7E-23 T 11-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain AFK25_05170 0008991c67726e7672bd437a268ace87 297 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 2 291 5.4E-65 T 11-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 AFK25_05170 0008991c67726e7672bd437a268ace87 297 Gene3D G3DSA:3.40.50.720 1 169 8.1E-48 T 11-10-2018 AFK25_05170 0008991c67726e7672bd437a268ace87 297 Gene3D G3DSA:1.10.1040.10 170 297 2.4E-41 T 11-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AFK25_09990 c43962fa8909bf4003201208956c90a3 256 Pfam PF11079 Bacterial protein YqhG of unknown function 1 253 1.2E-117 T 11-10-2018 IPR024562 Uncharacterised protein family YqhG AFK25_09990 c43962fa8909bf4003201208956c90a3 256 ProDom PD123329 YQHG BH2818 1 253 9.0E-72 T 11-10-2018 IPR024562 Uncharacterised protein family YqhG AFK25_07250 86a863946ccbe85afe94c8beba31f1d2 282 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 87 100 - T 11-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFK25_07250 86a863946ccbe85afe94c8beba31f1d2 282 SUPERFAMILY SSF53335 9 281 1.28E-85 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_07250 86a863946ccbe85afe94c8beba31f1d2 282 Pfam PF17284 Spermidine synthase tetramerisation domain 11 62 3.3E-18 T 11-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFK25_07250 86a863946ccbe85afe94c8beba31f1d2 282 Pfam PF01564 Spermine/spermidine synthase domain 67 245 2.8E-61 T 11-10-2018 AFK25_07250 86a863946ccbe85afe94c8beba31f1d2 282 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 11 281 38.238 T 11-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFK25_07250 86a863946ccbe85afe94c8beba31f1d2 282 Gene3D G3DSA:3.40.50.150 61 281 8.0E-74 T 11-10-2018 AFK25_07250 86a863946ccbe85afe94c8beba31f1d2 282 TIGRFAM TIGR00417 speE: spermidine synthase 12 275 4.7E-91 T 11-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFK25_07250 86a863946ccbe85afe94c8beba31f1d2 282 Gene3D G3DSA:2.30.140.10 9 60 5.4E-20 T 11-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AFK25_05070 502e9e7f483a5727e532c13336214ce1 119 Gene3D G3DSA:3.30.310.100 1 119 5.5E-49 T 11-10-2018 IPR036491 YugN-like superfamily AFK25_05070 502e9e7f483a5727e532c13336214ce1 119 Pfam PF08868 YugN-like family 6 102 7.1E-17 T 11-10-2018 IPR014967 Uncharacterised protein family, YugN-like AFK25_05070 502e9e7f483a5727e532c13336214ce1 119 SUPERFAMILY SSF160755 1 114 4.58E-43 T 11-10-2018 IPR036491 YugN-like superfamily AFK25_09880 9c8f6e63c6c34e574338d2e93fd8330d 386 Pfam PF09546 Stage III sporulation protein AE (spore_III_AE) 66 379 2.0E-103 T 11-10-2018 IPR014194 Sporulation stage III, protein AE AFK25_09880 9c8f6e63c6c34e574338d2e93fd8330d 386 TIGRFAM TIGR02829 spore_III_AE: stage III sporulation protein AE 1 379 4.1E-139 T 11-10-2018 IPR014194 Sporulation stage III, protein AE AFK25_08010 36c406310fc7504dd8f38a1dc0150094 383 PIRSF PIRSF026508 17 383 1.3E-113 T 11-10-2018 IPR008863 Toxic anion resistance AFK25_08010 36c406310fc7504dd8f38a1dc0150094 383 Pfam PF05816 Toxic anion resistance protein (TelA) 50 377 5.8E-123 T 11-10-2018 IPR008863 Toxic anion resistance AFK25_09950 38b23fef1f9907de90dd60a607ad6b8a 341 Gene3D G3DSA:3.40.50.12110 2 114 1.7E-47 T 11-10-2018 AFK25_09950 38b23fef1f9907de90dd60a607ad6b8a 341 SUPERFAMILY SSF102114 84 261 8.11E-6 T 11-10-2018 AFK25_09950 38b23fef1f9907de90dd60a607ad6b8a 341 TIGRFAM TIGR04070 photo_TT_lyase: spore photoproduct lyase 4 341 3.3E-156 T 11-10-2018 IPR023897 Spore photoproduct lyase GO:0003913 AFK25_09950 38b23fef1f9907de90dd60a607ad6b8a 341 Gene3D G3DSA:3.80.30.30 115 341 1.5E-90 T 11-10-2018 AFK25_01895 48c7f040b408ed0a0ce71e59664cbf42 106 SUPERFAMILY SSF101697 2 105 4.71E-48 T 11-10-2018 IPR036289 Hypothetical protein YfhH AFK25_01895 48c7f040b408ed0a0ce71e59664cbf42 106 Gene3D G3DSA:2.30.30.340 52 106 3.8E-26 T 11-10-2018 AFK25_01895 48c7f040b408ed0a0ce71e59664cbf42 106 Pfam PF08838 Protein of unknown function (DUF1811) 4 103 1.1E-45 T 11-10-2018 IPR014938 Protein of unknown function DUF1811 AFK25_01895 48c7f040b408ed0a0ce71e59664cbf42 106 Gene3D G3DSA:1.10.287.880 1 51 4.4E-27 T 11-10-2018 AFK25_02675 02f28e5eb6a4ceb9242883032709ceab 394 Pfam PF10672 S-adenosylmethionine-dependent methyltransferase 171 352 1.9E-21 T 11-10-2018 IPR019614 S-adenosylmethionine-dependent methyltransferase GO:0008168 AFK25_02675 02f28e5eb6a4ceb9242883032709ceab 394 Gene3D G3DSA:3.40.50.150 178 394 2.8E-70 T 11-10-2018 AFK25_02675 02f28e5eb6a4ceb9242883032709ceab 394 SUPERFAMILY SSF53335 78 383 1.2E-69 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_02675 02f28e5eb6a4ceb9242883032709ceab 394 SMART SM00359 2 87 1.5E-6 T 11-10-2018 IPR002478 PUA domain GO:0003723 AFK25_02675 02f28e5eb6a4ceb9242883032709ceab 394 Gene3D G3DSA:2.30.130.10 1 70 4.4E-25 T 11-10-2018 IPR036974 PUA domain superfamily GO:0003723 AFK25_02675 02f28e5eb6a4ceb9242883032709ceab 394 Gene3D G3DSA:3.30.750.80 72 177 1.4E-36 T 11-10-2018 AFK25_02675 02f28e5eb6a4ceb9242883032709ceab 394 SUPERFAMILY SSF88697 2 70 1.1E-15 T 11-10-2018 IPR015947 PUA-like superfamily AFK25_10765 e4fd2ffa09e96f7e8d7a8f9e85245452 146 TIGRFAM TIGR00256 TIGR00256: D-tyrosyl-tRNA(Tyr) deacylase 1 145 2.1E-58 T 11-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 AFK25_10765 e4fd2ffa09e96f7e8d7a8f9e85245452 146 Pfam PF02580 D-Tyr-tRNA(Tyr) deacylase 2 144 2.8E-57 T 11-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 AFK25_10765 e4fd2ffa09e96f7e8d7a8f9e85245452 146 SUPERFAMILY SSF69500 1 144 2.49E-57 T 11-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily AFK25_10765 e4fd2ffa09e96f7e8d7a8f9e85245452 146 Gene3D G3DSA:3.50.80.10 1 146 3.9E-59 T 11-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily AFK25_10765 e4fd2ffa09e96f7e8d7a8f9e85245452 146 Hamap MF_00518 D-aminoacyl-tRNA deacylase [dtd]. 1 145 35.152 T 11-10-2018 IPR003732 D-aminoacyl-tRNA deacylase DTD GO:0002161|GO:0005737|GO:0051499 AFK25_13705 5eaa2828433b2fbf640269cb3bf2ac04 293 Gene3D G3DSA:3.90.550.10 1 290 1.6E-96 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_13705 5eaa2828433b2fbf640269cb3bf2ac04 293 Pfam PF00483 Nucleotidyl transferase 6 261 2.9E-35 T 11-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AFK25_13705 5eaa2828433b2fbf640269cb3bf2ac04 293 TIGRFAM TIGR01099 galU: UTP--glucose-1-phosphate uridylyltransferase 4 263 4.7E-121 T 11-10-2018 IPR005771 UTP--glucose-1-phosphate uridylyltransferase, bacterial/archaeal-type GO:0003983|GO:0006011 KEGG: 00040+2.7.7.9|KEGG: 00052+2.7.7.9|KEGG: 00500+2.7.7.9|KEGG: 00520+2.7.7.9|MetaCyc: PWY-3801|MetaCyc: PWY-6527|MetaCyc: PWY-7238|MetaCyc: PWY-7343|MetaCyc: PWY-7817 AFK25_13705 5eaa2828433b2fbf640269cb3bf2ac04 293 SUPERFAMILY SSF53448 4 273 9.18E-70 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_11355 964e3e0c62a84a9233a1c547aeb8805a 91 Hamap MF_02013 Cell division protein ZapA [zapA]. 1 85 27.033 T 11-10-2018 IPR023688 Cell division protein ZapA, firmicutes GO:0051301 AFK25_11355 964e3e0c62a84a9233a1c547aeb8805a 91 SUPERFAMILY SSF102829 8 83 1.7E-20 T 11-10-2018 IPR036192 Cell division protein ZapA-like superfamily AFK25_11355 964e3e0c62a84a9233a1c547aeb8805a 91 Pfam PF05164 Cell division protein ZapA 9 81 3.7E-17 T 11-10-2018 IPR007838 Cell division protein ZapA-like AFK25_12450 59bfa100c6d870ffa66facf9334c07a3 301 SUPERFAMILY SSF103481 186 286 5.89E-14 T 11-10-2018 AFK25_12450 59bfa100c6d870ffa66facf9334c07a3 301 SUPERFAMILY SSF103481 37 141 5.49E-17 T 11-10-2018 AFK25_12450 59bfa100c6d870ffa66facf9334c07a3 301 Pfam PF00892 EamA-like transporter family 5 137 2.1E-18 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFK25_12450 59bfa100c6d870ffa66facf9334c07a3 301 Pfam PF00892 EamA-like transporter family 149 279 5.3E-22 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFK25_04175 c81a881c604abe0acb76f699bb75c1d3 109 Gene3D G3DSA:1.10.260.40 1 107 2.9E-19 T 11-10-2018 AFK25_04175 c81a881c604abe0acb76f699bb75c1d3 109 Pfam PF01381 Helix-turn-helix 6 60 5.8E-14 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFK25_04175 c81a881c604abe0acb76f699bb75c1d3 109 SMART SM00530 5 60 6.4E-13 T 11-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AFK25_04175 c81a881c604abe0acb76f699bb75c1d3 109 SUPERFAMILY SSF47413 2 69 9.12E-15 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFK25_13670 8c64de487ef4202a65548ee87b9976f4 345 SUPERFAMILY SSF53822 64 333 4.17E-67 T 11-10-2018 IPR028082 Periplasmic binding protein-like I AFK25_13670 8c64de487ef4202a65548ee87b9976f4 345 Gene3D G3DSA:3.40.50.2300 65 323 2.3E-73 T 11-10-2018 AFK25_13670 8c64de487ef4202a65548ee87b9976f4 345 Gene3D G3DSA:1.10.260.40 5 62 1.7E-22 T 11-10-2018 AFK25_13670 8c64de487ef4202a65548ee87b9976f4 345 SMART SM00354 3 74 4.9E-32 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_13670 8c64de487ef4202a65548ee87b9976f4 345 Pfam PF00356 Bacterial regulatory proteins, lacI family 5 51 6.1E-19 T 11-10-2018 IPR000843 LacI-type HTH domain GO:0003677|GO:0006355 AFK25_13670 8c64de487ef4202a65548ee87b9976f4 345 Pfam PF13377 Periplasmic binding protein-like domain 171 330 2.4E-32 T 11-10-2018 AFK25_13670 8c64de487ef4202a65548ee87b9976f4 345 Gene3D G3DSA:3.40.50.2300 163 327 2.3E-73 T 11-10-2018 AFK25_13670 8c64de487ef4202a65548ee87b9976f4 345 ProSitePatterns PS00356 LacI-type HTH domain signature. 6 24 - T 11-10-2018 AFK25_13670 8c64de487ef4202a65548ee87b9976f4 345 SUPERFAMILY SSF47413 2 62 4.22E-17 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFK25_06165 15807d7f9f69955db8d5fe85e26154d4 252 Pfam PF03746 LamB/YcsF family 4 241 2.7E-106 T 11-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 AFK25_06165 15807d7f9f69955db8d5fe85e26154d4 252 Gene3D G3DSA:3.20.20.370 2 252 3.3E-107 T 11-10-2018 AFK25_06165 15807d7f9f69955db8d5fe85e26154d4 252 SUPERFAMILY SSF88713 2 251 6.6E-104 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFK25_06165 15807d7f9f69955db8d5fe85e26154d4 252 Hamap MF_00691 UPF0271 protein YbgL [ybgL]. 2 246 48.276 T 11-10-2018 IPR005501 UPF0271 family, LamB/YcsF/PxpA KEGG: 00480+3.5.2.9|MetaCyc: PWY-4041|MetaCyc: PWY-7942 AFK25_13165 23b375419689139f7b7d132f4267d005 269 Gene3D G3DSA:1.20.58.1830 18 31 1.0E-46 T 11-10-2018 AFK25_13165 23b375419689139f7b7d132f4267d005 269 Pfam PF00700 Bacterial flagellin C-terminal helical region 183 262 5.0E-5 T 11-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 AFK25_13165 23b375419689139f7b7d132f4267d005 269 PRINTS PR00207 Flagellin signature 74 93 2.4E-11 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 AFK25_13165 23b375419689139f7b7d132f4267d005 269 PRINTS PR00207 Flagellin signature 35 52 2.4E-11 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 AFK25_13165 23b375419689139f7b7d132f4267d005 269 PRINTS PR00207 Flagellin signature 109 132 2.4E-11 T 11-10-2018 IPR001492 Flagellin GO:0005198|GO:0009420|GO:0071973 AFK25_13165 23b375419689139f7b7d132f4267d005 269 Pfam PF00669 Bacterial flagellin N-terminal helical region 4 138 5.7E-27 T 11-10-2018 IPR001029 Flagellin, D0/D1 domain GO:0005198|GO:0071973 AFK25_13165 23b375419689139f7b7d132f4267d005 269 SUPERFAMILY SSF64518 1 259 2.62E-55 T 11-10-2018 AFK25_13165 23b375419689139f7b7d132f4267d005 269 Gene3D G3DSA:1.10.8.410 216 269 1.7E-5 T 11-10-2018 AFK25_13165 23b375419689139f7b7d132f4267d005 269 Gene3D G3DSA:1.20.1330.10 43 174 1.0E-46 T 11-10-2018 AFK25_09845 06dd84e4c068bc81aa7a3c29c97fdfb5 128 SUPERFAMILY SSF48013 3 123 1.3E-39 T 11-10-2018 IPR035926 NusB-like superfamily AFK25_09845 06dd84e4c068bc81aa7a3c29c97fdfb5 128 Gene3D G3DSA:1.10.940.10 1 124 2.1E-44 T 11-10-2018 IPR035926 NusB-like superfamily AFK25_09845 06dd84e4c068bc81aa7a3c29c97fdfb5 128 Pfam PF01029 NusB family 4 124 9.6E-38 T 11-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 AFK25_09845 06dd84e4c068bc81aa7a3c29c97fdfb5 128 TIGRFAM TIGR01951 nusB: transcription antitermination factor NusB 2 126 2.6E-42 T 11-10-2018 IPR011605 NusB antitermination factor GO:0006353 AFK25_09845 06dd84e4c068bc81aa7a3c29c97fdfb5 128 Hamap MF_00073 Transcription antitermination protein NusB [nusB]. 1 128 23.946 T 11-10-2018 IPR011605 NusB antitermination factor GO:0006353 AFK25_13720 2b0204c88ec80aa4388c00b2089f8023 142 TIGRFAM TIGR01750 fabZ: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 138 3.6E-57 T 11-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 AFK25_13720 2b0204c88ec80aa4388c00b2089f8023 142 Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. 2 141 34.215 T 11-10-2018 IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ GO:0005737|GO:0006633|GO:0016836 KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 AFK25_13720 2b0204c88ec80aa4388c00b2089f8023 142 Gene3D G3DSA:3.10.129.10 1 140 2.1E-58 T 11-10-2018 AFK25_13720 2b0204c88ec80aa4388c00b2089f8023 142 SUPERFAMILY SSF54637 1 138 8.14E-48 T 11-10-2018 IPR029069 HotDog domain superfamily AFK25_13720 2b0204c88ec80aa4388c00b2089f8023 142 Pfam PF07977 FabA-like domain 11 133 2.3E-34 T 11-10-2018 IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ KEGG: 00061+4.2.1.59|KEGG: 00780+4.2.1.59|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 AFK25_05570 e5410af6c5db902fa2bd42d6ee5c21f8 245 TIGRFAM TIGR00088 trmD: tRNA (guanine(37)-N(1))-methyltransferase 1 235 4.2E-107 T 11-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFK25_05570 e5410af6c5db902fa2bd42d6ee5c21f8 245 Gene3D G3DSA:1.10.1270.20 165 245 6.4E-34 T 11-10-2018 IPR023148 tRNA (guanine-N1-)-methyltransferase, C-terminal GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFK25_05570 e5410af6c5db902fa2bd42d6ee5c21f8 245 Gene3D G3DSA:3.40.1280.10 1 164 9.1E-73 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFK25_05570 e5410af6c5db902fa2bd42d6ee5c21f8 245 Pfam PF01746 tRNA (Guanine-1)-methyltransferase 23 221 7.4E-76 T 11-10-2018 IPR016009 tRNA methyltransferase TRMD/TRM10-type domain MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFK25_05570 e5410af6c5db902fa2bd42d6ee5c21f8 245 SUPERFAMILY SSF75217 1 243 3.53E-105 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases AFK25_05570 e5410af6c5db902fa2bd42d6ee5c21f8 245 Hamap MF_00605 tRNA (guanine-N(1)-)-methyltransferase [trmD]. 1 245 116.336 T 11-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFK25_05570 e5410af6c5db902fa2bd42d6ee5c21f8 245 PIRSF PIRSF000386 1 245 4.1E-109 T 11-10-2018 IPR002649 tRNA (guanine-N1-)-methyltransferase, bacteria GO:0008033|GO:0052906 MetaCyc: PWY-6829|MetaCyc: PWY-7285|MetaCyc: PWY-7286 AFK25_00575 7a485ac72b18367e2607691ccde0b08e 82 SUPERFAMILY SSF55315 4 81 2.49E-19 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like AFK25_00575 7a485ac72b18367e2607691ccde0b08e 82 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 5 81 7.9E-14 T 11-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 AFK25_00575 7a485ac72b18367e2607691ccde0b08e 82 Hamap MF_00574 Putative ribosomal protein L7Ae-like. 2 82 23.927 T 11-10-2018 IPR023460 Ribosomal protein L7Ae, putative AFK25_00575 7a485ac72b18367e2607691ccde0b08e 82 Gene3D G3DSA:3.30.1330.30 1 81 5.8E-22 T 11-10-2018 IPR029064 50S ribosomal protein L30e-like AFK25_14215 e6c1ac48526dfb71c3a7cbb27532138d 404 Pfam PF07662 Na+ dependent nucleoside transporter C-terminus 195 403 1.0E-76 T 11-10-2018 IPR011657 Concentrative nucleoside transporter C-terminal domain Reactome: R-HSA-83936 AFK25_14215 e6c1ac48526dfb71c3a7cbb27532138d 404 Pfam PF07670 Nucleoside recognition 93 185 7.9E-8 T 11-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 AFK25_14215 e6c1ac48526dfb71c3a7cbb27532138d 404 TIGRFAM TIGR00804 nupC: nucleoside transporter, NupC family 6 403 1.3E-151 T 11-10-2018 IPR018270 Concentrative nucleoside transporter, metazoan/bacterial GO:0005337|GO:0016020|GO:1901642 Reactome: R-HSA-83936 AFK25_14215 e6c1ac48526dfb71c3a7cbb27532138d 404 Pfam PF01773 Na+ dependent nucleoside transporter N-terminus 8 80 4.5E-26 T 11-10-2018 IPR002668 Concentrative nucleoside transporter N-terminal domain Reactome: R-HSA-83936 AFK25_12605 0dea17e3f0a67bebce6b1311be8f3103 101 SUPERFAMILY SSF52833 2 99 1.38E-44 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_12605 0dea17e3f0a67bebce6b1311be8f3103 101 Pfam PF07315 Protein of unknown function (DUF1462) 5 97 4.4E-44 T 11-10-2018 IPR009190 Protein of unknown function DUF1462 AFK25_12605 0dea17e3f0a67bebce6b1311be8f3103 101 Gene3D G3DSA:3.40.30.30 1 101 1.5E-42 T 11-10-2018 IPR038218 YuzD-like superfamily AFK25_12605 0dea17e3f0a67bebce6b1311be8f3103 101 PIRSF PIRSF010603 1 101 5.5E-46 T 11-10-2018 IPR009190 Protein of unknown function DUF1462 AFK25_01875 4036bf7234da8832a80fb7d9ef695740 302 SUPERFAMILY SSF51735 1 300 9.07E-42 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_01875 4036bf7234da8832a80fb7d9ef695740 302 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 136 2.1E-13 T 11-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AFK25_01875 4036bf7234da8832a80fb7d9ef695740 302 TIGRFAM TIGR01777 yfcH: TIGR01777 family protein 3 296 1.1E-112 T 11-10-2018 IPR010099 Epimerase family protein SDR39U1 AFK25_01875 4036bf7234da8832a80fb7d9ef695740 302 Gene3D G3DSA:3.40.50.720 2 302 4.5E-75 T 11-10-2018 AFK25_01875 4036bf7234da8832a80fb7d9ef695740 302 Pfam PF08338 Domain of unknown function (DUF1731) 253 299 6.1E-22 T 11-10-2018 IPR013549 Domain of unknown function DUF1731 AFK25_01885 204418edb29cf17aa993b6fe65216ad4 222 Gene3D G3DSA:3.40.50.720 2 222 3.4E-58 T 11-10-2018 AFK25_01885 204418edb29cf17aa993b6fe65216ad4 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 170 187 3.3E-16 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_01885 204418edb29cf17aa993b6fe65216ad4 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 3 20 3.3E-16 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_01885 204418edb29cf17aa993b6fe65216ad4 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 149 168 3.3E-16 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_01885 204418edb29cf17aa993b6fe65216ad4 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 123 139 3.3E-16 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_01885 204418edb29cf17aa993b6fe65216ad4 222 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 76 87 3.3E-16 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_01885 204418edb29cf17aa993b6fe65216ad4 222 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 2 190 0.0065 T 11-10-2018 AFK25_01885 204418edb29cf17aa993b6fe65216ad4 222 SUPERFAMILY SSF51735 4 212 3.54E-57 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_01885 204418edb29cf17aa993b6fe65216ad4 222 Pfam PF00106 short chain dehydrogenase 4 189 1.4E-48 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_01885 204418edb29cf17aa993b6fe65216ad4 222 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 149 168 7.6E-7 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_01885 204418edb29cf17aa993b6fe65216ad4 222 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 76 87 7.6E-7 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_07020 b39d18622002068cb863466c14305f66 146 TIGRFAM TIGR01753 flav_short: flavodoxin 4 142 4.7E-47 T 11-10-2018 IPR010087 Flavodoxin, short chain GO:0010181 AFK25_07020 b39d18622002068cb863466c14305f66 146 Gene3D G3DSA:3.40.50.360 1 146 1.8E-40 T 11-10-2018 IPR029039 Flavoprotein-like superfamily AFK25_07020 b39d18622002068cb863466c14305f66 146 Pfam PF00258 Flavodoxin 7 136 6.7E-30 T 11-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 AFK25_07020 b39d18622002068cb863466c14305f66 146 SUPERFAMILY SSF52218 1 146 1.76E-44 T 11-10-2018 IPR029039 Flavoprotein-like superfamily AFK25_10470 dcf82e763bdde89ac2527073f8d59736 191 Pfam PF01966 HD domain 18 130 2.4E-16 T 11-10-2018 IPR006674 HD domain AFK25_10470 dcf82e763bdde89ac2527073f8d59736 191 TIGRFAM TIGR00488 TIGR00488: putative HD superfamily hydrolase 10 180 1.7E-66 T 11-10-2018 IPR005249 Conserved hypothetical protein CHP00488 AFK25_10470 dcf82e763bdde89ac2527073f8d59736 191 SUPERFAMILY SSF109604 5 180 1.35E-36 T 11-10-2018 AFK25_10470 dcf82e763bdde89ac2527073f8d59736 191 TIGRFAM TIGR00277 HDIG: HDIG domain 16 91 2.4E-7 T 11-10-2018 IPR006675 HDIG domain AFK25_10470 dcf82e763bdde89ac2527073f8d59736 191 Gene3D G3DSA:1.10.3210.10 1 186 4.7E-61 T 11-10-2018 AFK25_10470 dcf82e763bdde89ac2527073f8d59736 191 SMART SM00471 14 141 6.0E-10 T 11-10-2018 IPR003607 HD/PDEase domain AFK25_04320 46bfe0dbdbaf740fe3df9756fe512e1c 180 Gene3D G3DSA:3.40.50.1010 1 174 6.8E-23 T 11-10-2018 AFK25_04320 46bfe0dbdbaf740fe3df9756fe512e1c 180 Pfam PF01936 NYN domain 3 169 5.0E-26 T 11-10-2018 IPR021139 NYN domain, limkain-b1-type AFK25_14180 eed437ac9a838b09358e11e479d469e6 187 SUPERFAMILY SSF52833 1 186 1.95E-56 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_14180 eed437ac9a838b09358e11e479d469e6 187 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 156 182 4.7E-5 T 11-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFK25_14180 eed437ac9a838b09358e11e479d469e6 187 PIRSF PIRSF000239 1 187 9.9E-51 T 11-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFK25_14180 eed437ac9a838b09358e11e479d469e6 187 Pfam PF00578 AhpC/TSA family 4 133 9.1E-34 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFK25_14180 eed437ac9a838b09358e11e479d469e6 187 TIGRFAM TIGR03137 AhpC: peroxiredoxin 1 187 3.6E-103 T 11-10-2018 IPR017559 Alkyl hydroperoxide reductase subunit C GO:0006979|GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AFK25_14180 eed437ac9a838b09358e11e479d469e6 187 Gene3D G3DSA:3.40.30.10 1 186 1.4E-60 T 11-10-2018 AFK25_00700 788d66828357339389267fcdb6ef94f3 146 Gene3D G3DSA:3.100.10.10 66 146 1.0E-28 T 11-10-2018 AFK25_00700 788d66828357339389267fcdb6ef94f3 146 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 3 146 23.435 T 11-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 AFK25_00700 788d66828357339389267fcdb6ef94f3 146 TIGRFAM TIGR01071 rplO_bact: ribosomal protein uL15 2 143 6.6E-57 T 11-10-2018 IPR005749 Ribosomal protein L15, bacterial-type GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00700 788d66828357339389267fcdb6ef94f3 146 ProSitePatterns PS00475 Ribosomal protein L15 signature. 110 140 - T 11-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AFK25_00700 788d66828357339389267fcdb6ef94f3 146 SUPERFAMILY SSF52080 4 143 7.06E-52 T 11-10-2018 IPR036227 Ribosomal L18e/L15P superfamily AFK25_00700 788d66828357339389267fcdb6ef94f3 146 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 28 144 2.4E-39 T 11-10-2018 IPR021131 Ribosomal protein L18e/L15P AFK25_04735 1c1acd0ec3b54a2fa12f4629cec03715 124 Gene3D G3DSA:3.40.50.12740 1 124 6.7E-40 T 11-10-2018 AFK25_04735 1c1acd0ec3b54a2fa12f4629cec03715 124 SUPERFAMILY SSF52172 1 120 2.42E-37 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_04735 1c1acd0ec3b54a2fa12f4629cec03715 124 Pfam PF00072 Response regulator receiver domain 4 116 2.7E-28 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_04735 1c1acd0ec3b54a2fa12f4629cec03715 124 SMART SM00448 2 115 1.1E-37 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_07660 df49e65a6def1a2a38ba6ea524de89e0 47 Hamap MF_01505 Small, acid-soluble spore protein N [sspN]. 1 47 19.322 T 11-10-2018 IPR012612 Small acid-soluble spore protein, SspN GO:0030436|GO:0042601 AFK25_07660 df49e65a6def1a2a38ba6ea524de89e0 47 Pfam PF08177 Small acid-soluble spore protein N family 1 46 6.2E-27 T 11-10-2018 IPR012612 Small acid-soluble spore protein, SspN GO:0030436|GO:0042601 AFK25_12955 bc241bc152e344de5fd0c6dd682cd1db 321 Gene3D G3DSA:3.40.50.12300 1 315 2.5E-131 T 11-10-2018 IPR038136 Gluconeogenesis factor superfamily AFK25_12955 bc241bc152e344de5fd0c6dd682cd1db 321 SUPERFAMILY SSF142338 2 309 1.16E-106 T 11-10-2018 AFK25_12955 bc241bc152e344de5fd0c6dd682cd1db 321 Hamap MF_00973 Gluconeogenesis factor. 2 314 35.029 T 11-10-2018 IPR010119 Gluconeogenesis factor AFK25_12955 bc241bc152e344de5fd0c6dd682cd1db 321 TIGRFAM TIGR01826 CofD_related: conserved hypothetical protein 4 312 1.1E-124 T 11-10-2018 IPR010119 Gluconeogenesis factor AFK25_12955 bc241bc152e344de5fd0c6dd682cd1db 321 Pfam PF01933 Uncharacterised protein family UPF0052 4 288 1.9E-107 T 11-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 AFK25_07330 bd7749ad4afd285c8f1e8ea90046126e 75 SUPERFAMILY SSF52833 1 69 5.95E-13 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_07330 bd7749ad4afd285c8f1e8ea90046126e 75 Gene3D G3DSA:3.40.30.10 3 71 1.6E-13 T 11-10-2018 AFK25_07330 bd7749ad4afd285c8f1e8ea90046126e 75 Pfam PF00462 Glutaredoxin 4 61 5.1E-8 T 11-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 AFK25_11575 9d092251278d67d53bc3ee8c0d303a4c 207 TIGRFAM TIGR02840 spore_YtaF: putative sporulation protein YtaF 5 206 1.1E-64 T 11-10-2018 IPR014205 Sporulation protein YtaF AFK25_11575 9d092251278d67d53bc3ee8c0d303a4c 207 Pfam PF02659 Putative manganese efflux pump 123 203 2.1E-11 T 11-10-2018 IPR003810 Putative manganese efflux pump AFK25_11575 9d092251278d67d53bc3ee8c0d303a4c 207 Pfam PF02659 Putative manganese efflux pump 3 82 3.0E-11 T 11-10-2018 IPR003810 Putative manganese efflux pump AFK25_11000 097fd9ffa680b20d8779f5301ef660d4 322 Pfam PF11104 Type IV pilus assembly protein PilM; 15 214 6.5E-16 T 11-10-2018 IPR005883 Type IV pilus assembly protein PilM AFK25_11000 097fd9ffa680b20d8779f5301ef660d4 322 Gene3D G3DSA:3.30.420.40 1 134 1.3E-6 T 11-10-2018 AFK25_03105 09c1a8c2eba392c2767fb317c2e41575 287 SUPERFAMILY SSF56529 66 286 3.01E-79 T 11-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AFK25_03105 09c1a8c2eba392c2767fb317c2e41575 287 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 80 286 2.6E-73 T 11-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 AFK25_03105 09c1a8c2eba392c2767fb317c2e41575 287 Gene3D G3DSA:3.90.850.10 74 287 1.7E-90 T 11-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AFK25_07670 845885d6cb9964bb734cb1cca924047a 171 SUPERFAMILY SSF52833 30 168 4.41E-49 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_07670 845885d6cb9964bb734cb1cca924047a 171 ProSitePatterns PS00194 Thioredoxin family active site. 62 80 - T 11-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFK25_07670 845885d6cb9964bb734cb1cca924047a 171 Pfam PF00578 AhpC/TSA family 34 151 5.0E-36 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFK25_07670 845885d6cb9964bb734cb1cca924047a 171 Gene3D G3DSA:3.40.30.10 18 171 6.8E-53 T 11-10-2018 AFK25_06180 bbea5366c327fa1afb2653ed33cdea8d 379 Pfam PF07282 Putative transposase DNA-binding domain 289 359 1.7E-24 T 11-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFK25_06180 bbea5366c327fa1afb2653ed33cdea8d 379 TIGRFAM TIGR01766 tspaseT_teng_C: transposase, IS605 OrfB family 243 316 1.4E-14 T 11-10-2018 IPR010095 Transposase IS605, OrfB, C-terminal AFK25_06180 bbea5366c327fa1afb2653ed33cdea8d 379 Pfam PF01385 Probable transposase 166 275 3.3E-31 T 11-10-2018 IPR001959 Probable transposase, IS891/IS1136/IS1341 AFK25_06180 bbea5366c327fa1afb2653ed33cdea8d 379 Pfam PF12323 Helix-turn-helix domain 1 48 1.2E-22 T 11-10-2018 IPR021027 Transposase, putative, helix-turn-helix domain AFK25_13780 63995a908260d800fe40eed16d11f318 503 Pfam PF00361 Proton-conducting membrane transporter 139 435 1.8E-67 T 11-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13780 63995a908260d800fe40eed16d11f318 503 TIGRFAM TIGR01972 NDH_I_M: proton-translocating NADH-quinone oxidoreductase, chain M 6 499 1.1E-140 T 11-10-2018 IPR010227 NADH-quinone oxidoreductase, chain M/4 GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13780 63995a908260d800fe40eed16d11f318 503 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 342 361 3.6E-35 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13780 63995a908260d800fe40eed16d11f318 503 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 254 278 3.6E-35 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13780 63995a908260d800fe40eed16d11f318 503 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 175 199 3.6E-35 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13780 63995a908260d800fe40eed16d11f318 503 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 394 420 3.6E-35 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13780 63995a908260d800fe40eed16d11f318 503 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 145 164 3.6E-35 T 11-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_12320 601c0211d43c708226a581c60bf24d0e 318 SUPERFAMILY SSF161111 16 214 9.15E-59 T 11-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFK25_12320 601c0211d43c708226a581c60bf24d0e 318 SUPERFAMILY SSF160240 218 291 7.06E-8 T 11-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AFK25_12320 601c0211d43c708226a581c60bf24d0e 318 Gene3D G3DSA:1.20.1510.10 16 213 6.7E-47 T 11-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFK25_12320 601c0211d43c708226a581c60bf24d0e 318 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 17 291 3.0E-91 T 11-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFK25_12320 601c0211d43c708226a581c60bf24d0e 318 Pfam PF01545 Cation efflux family 21 213 8.3E-51 T 11-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFK25_00560 1c93a767949a298083c78a979cdd8323 199 Pfam PF05175 Methyltransferase small domain 30 194 3.7E-50 T 11-10-2018 IPR007848 Methyltransferase small domain GO:0008168 AFK25_00560 1c93a767949a298083c78a979cdd8323 199 SUPERFAMILY SSF53335 9 195 4.67E-37 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_00560 1c93a767949a298083c78a979cdd8323 199 Gene3D G3DSA:3.40.50.150 6 199 3.6E-46 T 11-10-2018 AFK25_06245 2f4967433041b493aad83bf191f41dee 459 Gene3D G3DSA:1.10.10.10 7 83 1.1E-22 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_06245 2f4967433041b493aad83bf191f41dee 459 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 51 67 5.4E-6 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_06245 2f4967433041b493aad83bf191f41dee 459 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 37 51 5.4E-6 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_06245 2f4967433041b493aad83bf191f41dee 459 Pfam PF00155 Aminotransferase class I and II 114 401 3.4E-23 T 11-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AFK25_06245 2f4967433041b493aad83bf191f41dee 459 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 77 4.7E-15 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_06245 2f4967433041b493aad83bf191f41dee 459 Gene3D G3DSA:3.40.640.10 91 452 6.8E-106 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_06245 2f4967433041b493aad83bf191f41dee 459 SUPERFAMILY SSF53383 74 458 1.39E-72 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_06245 2f4967433041b493aad83bf191f41dee 459 SUPERFAMILY SSF46785 7 86 2.08E-20 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_06245 2f4967433041b493aad83bf191f41dee 459 SMART SM00345 18 77 1.3E-14 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_09030 5ed6e3fe0b256dd1906bbe7c2c2a538e 219 Pfam PF07238 PilZ domain 98 206 2.9E-14 T 11-10-2018 IPR009875 PilZ domain GO:0035438 AFK25_09030 5ed6e3fe0b256dd1906bbe7c2c2a538e 219 Gene3D G3DSA:2.40.10.220 96 218 7.7E-6 T 11-10-2018 AFK25_09030 5ed6e3fe0b256dd1906bbe7c2c2a538e 219 Pfam PF12945 Flagellar protein YcgR 3 89 6.3E-20 T 11-10-2018 IPR009926 Type III secretion system flagellar brake protein YcgR, N-terminal AFK25_09030 5ed6e3fe0b256dd1906bbe7c2c2a538e 219 SUPERFAMILY SSF141371 98 180 2.94E-6 T 11-10-2018 AFK25_02500 57669dd478250ea8a503849fbde707ed 320 SUPERFAMILY SSF50969 42 219 1.18E-7 T 11-10-2018 IPR011044 Quinoprotein amine dehydrogenase, beta chain-like AFK25_02500 57669dd478250ea8a503849fbde707ed 320 Gene3D G3DSA:2.130.10.10 16 307 2.7E-6 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFK25_10655 e58abcfe212546bf85e36f5df7843da0 309 Pfam PF01136 Peptidase family U32 75 306 6.8E-68 T 11-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 AFK25_01205 1164cb40ed20178967e07ae02a2c50ca 232 SUPERFAMILY SSF53067 3 106 5.05E-29 T 11-10-2018 AFK25_01205 1164cb40ed20178967e07ae02a2c50ca 232 Gene3D G3DSA:3.30.420.40 95 188 1.1E-51 T 11-10-2018 AFK25_01205 1164cb40ed20178967e07ae02a2c50ca 232 Gene3D G3DSA:3.30.420.40 3 215 1.1E-51 T 11-10-2018 AFK25_01205 1164cb40ed20178967e07ae02a2c50ca 232 SUPERFAMILY SSF53067 108 213 3.04E-15 T 11-10-2018 AFK25_01205 1164cb40ed20178967e07ae02a2c50ca 232 Pfam PF00814 Glycoprotease family 32 223 1.3E-36 T 11-10-2018 IPR000905 Gcp-like domain AFK25_01205 1164cb40ed20178967e07ae02a2c50ca 232 TIGRFAM TIGR03725 T6A_YeaZ: tRNA threonylcarbamoyl adenosine modification protein YeaZ 3 215 1.0E-55 T 11-10-2018 IPR022496 tRNA threonylcarbamoyl adenosine modification protein TsaB GO:0002949 AFK25_01545 43d0af56e54da4686b5a79e5e46d636c 194 Gene3D G3DSA:3.40.50.1390 7 155 1.2E-26 T 11-10-2018 AFK25_01545 43d0af56e54da4686b5a79e5e46d636c 194 SMART SM00857 9 150 4.0E-29 T 11-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFK25_01545 43d0af56e54da4686b5a79e5e46d636c 194 Pfam PF00239 Resolvase, N terminal domain 10 148 1.2E-28 T 11-10-2018 IPR006119 Resolvase, N-terminal catalytic domain GO:0000150|GO:0003677|GO:0006310 AFK25_01545 43d0af56e54da4686b5a79e5e46d636c 194 SUPERFAMILY SSF53041 10 148 1.06E-25 T 11-10-2018 IPR036162 Resolvase-like, N-terminal catalytic domain superfamily GO:0000150|GO:0003677|GO:0006310 AFK25_14280 a3a91980f04f79aefdd2a1192097933b 242 Pfam PF04055 Radical SAM superfamily 22 186 3.3E-32 T 11-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AFK25_14280 a3a91980f04f79aefdd2a1192097933b 242 Pfam PF13353 4Fe-4S single cluster domain 14 151 3.4E-23 T 11-10-2018 AFK25_14280 a3a91980f04f79aefdd2a1192097933b 242 TIGRFAM TIGR02493 PFLA: pyruvate formate-lyase 1-activating enzyme 5 239 1.2E-102 T 11-10-2018 IPR012838 Pyruvate formate-lyase 1 activating enzyme GO:0043365|GO:0055114 AFK25_14280 a3a91980f04f79aefdd2a1192097933b 242 Gene3D G3DSA:3.20.20.70 1 242 5.4E-98 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_14280 a3a91980f04f79aefdd2a1192097933b 242 ProSitePatterns PS01087 Radical activating enzymes signature. 16 37 - T 11-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 AFK25_14280 a3a91980f04f79aefdd2a1192097933b 242 SUPERFAMILY SSF102114 20 222 5.36E-32 T 11-10-2018 AFK25_13940 6cd6b0f6684c13c20419ca31b777b620 206 PIRSF PIRSF035805 5 202 2.1E-67 T 11-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 AFK25_13940 6cd6b0f6684c13c20419ca31b777b620 206 Hamap MF_00124 Thymidine kinase [tdk]. 7 190 38.534 T 11-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 AFK25_13940 6cd6b0f6684c13c20419ca31b777b620 206 Pfam PF00265 Thymidine kinase 8 187 2.8E-59 T 11-10-2018 IPR001267 Thymidine kinase GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 AFK25_13940 6cd6b0f6684c13c20419ca31b777b620 206 Gene3D G3DSA:3.40.50.300 1 141 1.0E-60 T 11-10-2018 AFK25_13940 6cd6b0f6684c13c20419ca31b777b620 206 Gene3D G3DSA:3.30.60.20 142 205 1.9E-27 T 11-10-2018 AFK25_13940 6cd6b0f6684c13c20419ca31b777b620 206 ProSitePatterns PS00603 Thymidine kinase cellular-type signature. 174 187 - T 11-10-2018 IPR020633 Thymidine kinase, conserved site GO:0004797|GO:0005524 KEGG: 00240+2.7.1.21|KEGG: 00983+2.7.1.21|MetaCyc: PWY-7199|Reactome: R-HSA-539107|Reactome: R-HSA-73614 AFK25_13940 6cd6b0f6684c13c20419ca31b777b620 206 SUPERFAMILY SSF52540 8 142 2.12E-44 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_13940 6cd6b0f6684c13c20419ca31b777b620 206 SUPERFAMILY SSF57716 142 199 4.75E-17 T 11-10-2018 AFK25_06600 4c522a2a7663027ce058a077efea7e14 442 Pfam PF00665 Integrase core domain 280 395 6.4E-22 T 11-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFK25_06600 4c522a2a7663027ce058a077efea7e14 442 Pfam PF13276 HTH-like domain 195 250 1.5E-11 T 11-10-2018 IPR025948 HTH-like domain AFK25_06600 4c522a2a7663027ce058a077efea7e14 442 SUPERFAMILY SSF53098 272 437 1.82E-28 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_06600 4c522a2a7663027ce058a077efea7e14 442 Gene3D G3DSA:3.30.420.10 274 439 2.2E-8 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFK25_06530 95dac39ef6cb03efda5e8ce047ca373a 242 SUPERFAMILY SSF52540 1 234 8.34E-84 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_06530 95dac39ef6cb03efda5e8ce047ca373a 242 SMART SM00382 26 213 2.1E-17 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_06530 95dac39ef6cb03efda5e8ce047ca373a 242 Gene3D G3DSA:3.40.50.300 1 241 2.8E-81 T 11-10-2018 AFK25_06530 95dac39ef6cb03efda5e8ce047ca373a 242 Pfam PF00005 ABC transporter 17 165 2.6E-37 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_06530 95dac39ef6cb03efda5e8ce047ca373a 242 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_06530 95dac39ef6cb03efda5e8ce047ca373a 242 PIRSF PIRSF039085 1 241 1.3E-117 T 11-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 AFK25_02295 12492a6404eddf1e67e44e72ebd974ad 330 TIGRFAM TIGR01446 DnaD_dom: DnaD domain protein 192 261 1.3E-20 T 11-10-2018 IPR006343 DnaD domain AFK25_02295 12492a6404eddf1e67e44e72ebd974ad 330 Gene3D G3DSA:1.10.10.630 190 261 2.7E-25 T 11-10-2018 IPR034829 DnaD-like domain superfamily AFK25_02295 12492a6404eddf1e67e44e72ebd974ad 330 Pfam PF07261 Replication initiation and membrane attachment 192 262 3.4E-18 T 11-10-2018 IPR006343 DnaD domain AFK25_02295 12492a6404eddf1e67e44e72ebd974ad 330 SUPERFAMILY SSF158499 192 255 1.28E-16 T 11-10-2018 IPR034829 DnaD-like domain superfamily AFK25_00095 f4cee882cde16055ddd947339a0a5ceb 424 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 223 400 6.6E-38 T 11-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AFK25_00095 f4cee882cde16055ddd947339a0a5ceb 424 Gene3D G3DSA:1.10.287.40 1 105 5.2E-27 T 11-10-2018 AFK25_00095 f4cee882cde16055ddd947339a0a5ceb 424 Hamap MF_00176 Serine--tRNA ligase [serS]. 1 422 44.86 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFK25_00095 f4cee882cde16055ddd947339a0a5ceb 424 SUPERFAMILY SSF46589 1 113 8.37E-33 T 11-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 AFK25_00095 f4cee882cde16055ddd947339a0a5ceb 424 PIRSF PIRSF001529 1 424 4.6E-195 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFK25_00095 f4cee882cde16055ddd947339a0a5ceb 424 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 1 108 3.9E-33 T 11-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 AFK25_00095 f4cee882cde16055ddd947339a0a5ceb 424 Gene3D G3DSA:3.30.930.10 106 424 4.0E-132 T 11-10-2018 AFK25_00095 f4cee882cde16055ddd947339a0a5ceb 424 SUPERFAMILY SSF55681 117 422 1.49E-108 T 11-10-2018 AFK25_00095 f4cee882cde16055ddd947339a0a5ceb 424 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 417 1.5E-185 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFK25_00095 f4cee882cde16055ddd947339a0a5ceb 424 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 7.9E-31 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFK25_00095 f4cee882cde16055ddd947339a0a5ceb 424 PRINTS PR00981 Seryl-tRNA synthetase signature 276 289 7.9E-31 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFK25_00095 f4cee882cde16055ddd947339a0a5ceb 424 PRINTS PR00981 Seryl-tRNA synthetase signature 333 349 7.9E-31 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFK25_00095 f4cee882cde16055ddd947339a0a5ceb 424 PRINTS PR00981 Seryl-tRNA synthetase signature 264 276 7.9E-31 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFK25_00095 f4cee882cde16055ddd947339a0a5ceb 424 PRINTS PR00981 Seryl-tRNA synthetase signature 316 329 7.9E-31 T 11-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AFK25_06745 532cffdecccfe42ebf10f68dc5e7f419 86 Gene3D G3DSA:3.30.110.20 1 86 4.6E-37 T 11-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 AFK25_06745 532cffdecccfe42ebf10f68dc5e7f419 86 ProDom PD061837 SPORULATION V STAGE S SPOVS-RELATED SPOVS CELL SEPTATION SPOVS3 RELATED 3 86 5.0E-33 T 11-10-2018 IPR007347 Sporulation stage V, protein S AFK25_06745 532cffdecccfe42ebf10f68dc5e7f419 86 Pfam PF04232 Stage V sporulation protein S (SpoVS) 2 84 9.9E-41 T 11-10-2018 IPR007347 Sporulation stage V, protein S AFK25_06550 b97c30924eb4cac3eb3e0f4bfa040613 320 Pfam PF00535 Glycosyl transferase family 2 5 167 9.5E-36 T 11-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AFK25_06550 b97c30924eb4cac3eb3e0f4bfa040613 320 Gene3D G3DSA:3.90.550.10 1 195 3.2E-39 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_06550 b97c30924eb4cac3eb3e0f4bfa040613 320 SUPERFAMILY SSF53448 2 256 3.73E-40 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_07125 03525d55e64dc731dc20dcee4ac24f4b 139 SUPERFAMILY SSF50022 40 107 1.23E-7 T 11-10-2018 IPR036922 Rieske [2Fe-2S] iron-sulphur domain superfamily GO:0016491|GO:0051537|GO:0055114 AFK25_07485 ca6720416a92691cffa46b67756e725c 303 Pfam PF00005 ABC transporter 21 161 1.8E-31 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_07485 ca6720416a92691cffa46b67756e725c 303 SMART SM00382 29 210 3.7E-12 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_07485 ca6720416a92691cffa46b67756e725c 303 SUPERFAMILY SSF52540 9 228 5.22E-61 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_07485 ca6720416a92691cffa46b67756e725c 303 ProSitePatterns PS00211 ABC transporters family signature. 133 147 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_07485 ca6720416a92691cffa46b67756e725c 303 Gene3D G3DSA:3.40.50.300 1 235 8.6E-62 T 11-10-2018 AFK25_05235 bb79eef75ad50bb6f4ec7b7ac842d485 259 Pfam PF03799 Cell division protein FtsQ 123 228 9.0E-9 T 11-10-2018 IPR005548 Cell division protein FtsQ/DivIB AFK25_05235 bb79eef75ad50bb6f4ec7b7ac842d485 259 Gene3D G3DSA:3.10.20.310 48 116 4.8E-8 T 11-10-2018 AFK25_05235 bb79eef75ad50bb6f4ec7b7ac842d485 259 Gene3D G3DSA:3.40.50.10960 117 232 3.3E-40 T 11-10-2018 AFK25_05235 bb79eef75ad50bb6f4ec7b7ac842d485 259 Pfam PF08478 POTRA domain, FtsQ-type 51 118 9.6E-19 T 11-10-2018 IPR013685 POTRA domain, FtsQ-type AFK25_05235 bb79eef75ad50bb6f4ec7b7ac842d485 259 Hamap MF_00912 Cell division protein DivIB [divIB]. 9 250 28.136 T 11-10-2018 IPR026580 Cell division protein DivIB AFK25_11935 b4dd1af4892666ecc45967b5e846b604 108 Pfam PF00085 Thioredoxin 8 101 1.4E-17 T 11-10-2018 IPR013766 Thioredoxin domain GO:0045454 AFK25_11935 b4dd1af4892666ecc45967b5e846b604 108 Gene3D G3DSA:3.40.30.10 1 103 3.6E-23 T 11-10-2018 AFK25_11935 b4dd1af4892666ecc45967b5e846b604 108 SUPERFAMILY SSF52833 4 103 4.17E-25 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_09770 cea0fa8f921c5872a825f4c5007f334d 367 SUPERFAMILY SSF51735 141 348 7.65E-62 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_09770 cea0fa8f921c5872a825f4c5007f334d 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 66 80 1.7E-22 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFK25_09770 cea0fa8f921c5872a825f4c5007f334d 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 176 196 1.7E-22 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFK25_09770 cea0fa8f921c5872a825f4c5007f334d 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 132 154 1.7E-22 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFK25_09770 cea0fa8f921c5872a825f4c5007f334d 367 PRINTS PR00082 Glutamate/leucine/phenylalanine/valine dehydrogenase signature 286 297 1.7E-22 T 11-10-2018 IPR006095 Glutamate/phenylalanine/leucine/valine dehydrogenase GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFK25_09770 cea0fa8f921c5872a825f4c5007f334d 367 Gene3D G3DSA:3.40.50.10860 10 343 1.3E-157 T 11-10-2018 AFK25_09770 cea0fa8f921c5872a825f4c5007f334d 367 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 217 349 3.7E-13 T 11-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFK25_09770 cea0fa8f921c5872a825f4c5007f334d 367 Pfam PF00208 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase 148 200 1.9E-6 T 11-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFK25_09770 cea0fa8f921c5872a825f4c5007f334d 367 SUPERFAMILY SSF53223 4 143 4.16E-50 T 11-10-2018 AFK25_09770 cea0fa8f921c5872a825f4c5007f334d 367 SMART SM00839 144 351 2.3E-79 T 11-10-2018 IPR006096 Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFK25_09770 cea0fa8f921c5872a825f4c5007f334d 367 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 22 131 9.6E-28 T 11-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFK25_09770 cea0fa8f921c5872a825f4c5007f334d 367 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 74 87 - T 11-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AFK25_09770 cea0fa8f921c5872a825f4c5007f334d 367 PIRSF PIRSF000188 1 353 2.7E-172 T 11-10-2018 IPR016211 Glutamate/phenylalanine/leucine/valine dehydrogenase, bacterial/archaeal GO:0016639|GO:0055114 AFK25_09770 cea0fa8f921c5872a825f4c5007f334d 367 Gene3D G3DSA:3.40.50.720 134 336 1.3E-157 T 11-10-2018 AFK25_09475 d1af8a1e40db4b26076fa15869b53a86 79 Pfam PF10827 Protein of unknown function (DUF2552) 2 79 8.5E-44 T 11-10-2018 IPR020157 Uncharacterised protein family YqkC AFK25_09475 d1af8a1e40db4b26076fa15869b53a86 79 ProDom PD058987 CYTOSOLIC YQKC 22 79 2.0E-16 T 11-10-2018 IPR020157 Uncharacterised protein family YqkC AFK25_03130 e1b04319943c7d198e74eb8989affc27 616 Pfam PF13537 Glutamine amidotransferase domain 48 169 7.1E-47 T 11-10-2018 IPR017932 Glutamine amidotransferase type 2 domain AFK25_03130 e1b04319943c7d198e74eb8989affc27 616 PIRSF PIRSF001589 1 609 1.2E-144 T 11-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 AFK25_03130 e1b04319943c7d198e74eb8989affc27 616 Gene3D G3DSA:3.60.20.10 2 186 9.3E-63 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFK25_03130 e1b04319943c7d198e74eb8989affc27 616 SUPERFAMILY SSF56235 2 226 2.4E-64 T 11-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AFK25_03130 e1b04319943c7d198e74eb8989affc27 616 TIGRFAM TIGR01536 asn_synth_AEB: asparagine synthase (glutamine-hydrolyzing) 2 534 7.7E-170 T 11-10-2018 IPR006426 Asparagine synthase, glutamine-hydrolyzing GO:0004066|GO:0006529 KEGG: 00250+6.3.5.4|Reactome: R-HSA-380994|Reactome: R-HSA-70614 AFK25_03130 e1b04319943c7d198e74eb8989affc27 616 Pfam PF00733 Asparagine synthase 242 605 2.4E-97 T 11-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 AFK25_03130 e1b04319943c7d198e74eb8989affc27 616 SUPERFAMILY SSF52402 231 575 8.9E-77 T 11-10-2018 AFK25_07095 3aa65f8d00f4e9ff72e5493be4371b52 64 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 2 60 17.552 T 11-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 AFK25_07095 3aa65f8d00f4e9ff72e5493be4371b52 64 Pfam PF02416 mttA/Hcf106 family 5 60 6.9E-22 T 11-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 AFK25_07095 3aa65f8d00f4e9ff72e5493be4371b52 64 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 22 41 2.0E-8 T 11-10-2018 AFK25_07095 3aa65f8d00f4e9ff72e5493be4371b52 64 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 41 59 2.0E-8 T 11-10-2018 AFK25_07095 3aa65f8d00f4e9ff72e5493be4371b52 64 PRINTS PR01506 Bacterial sec-independent translocation TatB protein signature 2 22 2.0E-8 T 11-10-2018 AFK25_07095 3aa65f8d00f4e9ff72e5493be4371b52 64 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 5 50 2.2E-20 T 11-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 AFK25_06900 a5ba34589a7cc01d41c8b3791bf7681a 119 SMART SM00448 2 114 3.3E-38 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_06900 a5ba34589a7cc01d41c8b3791bf7681a 119 Gene3D G3DSA:3.40.50.2300 1 119 5.9E-41 T 11-10-2018 AFK25_06900 a5ba34589a7cc01d41c8b3791bf7681a 119 SUPERFAMILY SSF52172 1 119 1.38E-41 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_06900 a5ba34589a7cc01d41c8b3791bf7681a 119 Pfam PF00072 Response regulator receiver domain 4 115 2.2E-34 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_10525 11108f052abd759af29edeef2c1a6c73 437 Pfam PF02386 Cation transport protein 28 422 8.4E-56 T 11-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 AFK25_10525 11108f052abd759af29edeef2c1a6c73 437 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 26 408 3.2E-112 T 11-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 AFK25_02565 53785f0fe425e07a51733bb7f5a75502 75 Gene3D G3DSA:3.30.110.40 1 75 1.8E-29 T 11-10-2018 IPR036868 TusA-like domain superfamily AFK25_02565 53785f0fe425e07a51733bb7f5a75502 75 Pfam PF01206 Sulfurtransferase TusA 6 74 3.0E-23 T 11-10-2018 IPR001455 TusA-like domain AFK25_02565 53785f0fe425e07a51733bb7f5a75502 75 SUPERFAMILY SSF64307 2 74 7.46E-25 T 11-10-2018 IPR036868 TusA-like domain superfamily AFK25_02565 53785f0fe425e07a51733bb7f5a75502 75 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 7 31 - T 11-10-2018 IPR001455 TusA-like domain AFK25_09220 f780aaf26575aafb1ddeb0704d5d7edf 238 Gene3D G3DSA:1.10.10.10 136 238 2.8E-35 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_09220 f780aaf26575aafb1ddeb0704d5d7edf 238 Pfam PF00486 Transcriptional regulatory protein, C terminal 156 233 3.3E-28 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFK25_09220 f780aaf26575aafb1ddeb0704d5d7edf 238 Gene3D G3DSA:3.40.50.2300 1 127 2.9E-42 T 11-10-2018 AFK25_09220 f780aaf26575aafb1ddeb0704d5d7edf 238 SUPERFAMILY SSF52172 4 191 3.37E-44 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_09220 f780aaf26575aafb1ddeb0704d5d7edf 238 Pfam PF00072 Response regulator receiver domain 7 115 5.9E-33 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_09220 f780aaf26575aafb1ddeb0704d5d7edf 238 SMART SM00862 156 233 1.6E-27 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFK25_09220 f780aaf26575aafb1ddeb0704d5d7edf 238 SMART SM00448 5 115 4.2E-49 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_05715 6b3ffd898a07dec77e6266937c9092c5 142 Pfam PF03748 Flagellar basal body-associated protein FliL 51 142 1.1E-17 T 11-10-2018 IPR005503 Flagellar basal body-associated protein FliL GO:0006935|GO:0009425|GO:0071973 AFK25_12590 282cd4deb2a0249cf34a2d3ed635326b 79 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 2 78 4.0E-27 T 11-10-2018 AFK25_12590 282cd4deb2a0249cf34a2d3ed635326b 79 Pfam PF07293 Protein of unknown function (DUF1450) 2 76 3.6E-36 T 11-10-2018 IPR009910 Protein of unknown function DUF1450 AFK25_05515 494f7eee19c0d4f7e2a74bb845422a34 247 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 12 245 8.5E-77 T 11-10-2018 AFK25_05515 494f7eee19c0d4f7e2a74bb845422a34 247 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 142 170 - T 11-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AFK25_05515 494f7eee19c0d4f7e2a74bb845422a34 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 209 229 6.2E-50 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_05515 494f7eee19c0d4f7e2a74bb845422a34 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 82 93 6.2E-50 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_05515 494f7eee19c0d4f7e2a74bb845422a34 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 129 145 6.2E-50 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_05515 494f7eee19c0d4f7e2a74bb845422a34 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 155 174 6.2E-50 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_05515 494f7eee19c0d4f7e2a74bb845422a34 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 176 193 6.2E-50 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_05515 494f7eee19c0d4f7e2a74bb845422a34 247 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 7 24 6.2E-50 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_05515 494f7eee19c0d4f7e2a74bb845422a34 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 135 143 3.1E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_05515 494f7eee19c0d4f7e2a74bb845422a34 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 82 93 3.1E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_05515 494f7eee19c0d4f7e2a74bb845422a34 247 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 155 174 3.1E-15 T 11-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AFK25_05515 494f7eee19c0d4f7e2a74bb845422a34 247 Gene3D G3DSA:3.40.50.720 1 247 3.6E-95 T 11-10-2018 AFK25_05515 494f7eee19c0d4f7e2a74bb845422a34 247 SUPERFAMILY SSF51735 4 247 7.66E-98 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_05515 494f7eee19c0d4f7e2a74bb845422a34 247 TIGRFAM TIGR01830 3oxo_ACP_reduc: 3-oxoacyl-[acyl-carrier-protein] reductase 8 246 1.4E-110 T 11-10-2018 IPR011284 3-oxoacyl-(acyl-carrier-protein) reductase GO:0004316|GO:0006633|GO:0051287|GO:0055114 KEGG: 00061+1.1.1.100|KEGG: 00780+1.1.1.100|MetaCyc: PWY-5367|MetaCyc: PWY-5971|MetaCyc: PWY-5973|MetaCyc: PWY-5989|MetaCyc: PWY-5994|MetaCyc: PWY-6113|MetaCyc: PWY-6282|MetaCyc: PWY-6519|MetaCyc: PWY-7388|MetaCyc: PWY-7663|MetaCyc: PWY-7664|MetaCyc: PWY-7858|MetaCyc: PWYG-321 AFK25_05515 494f7eee19c0d4f7e2a74bb845422a34 247 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 6 186 6.8E-6 T 11-10-2018 AFK25_04020 4dd6d1f690acc55a9106ac740664ea33 171 SUPERFAMILY SSF53098 29 141 3.98E-9 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_04020 4dd6d1f690acc55a9106ac740664ea33 171 Gene3D G3DSA:3.30.420.470 2 168 2.4E-15 T 11-10-2018 AFK25_04020 4dd6d1f690acc55a9106ac740664ea33 171 Pfam PF13358 DDE superfamily endonuclease 2 144 3.1E-37 T 11-10-2018 IPR038717 Tc1-like transposase, DDE domain AFK25_09915 e0b4771e7d6f52ea81ad2115122cffdf 353 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 283 295 - T 11-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site AFK25_09915 e0b4771e7d6f52ea81ad2115122cffdf 353 Gene3D G3DSA:3.90.230.10 126 352 1.6E-87 T 11-10-2018 AFK25_09915 e0b4771e7d6f52ea81ad2115122cffdf 353 Pfam PF01321 Creatinase/Prolidase N-terminal domain 4 127 1.3E-26 T 11-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 AFK25_09915 e0b4771e7d6f52ea81ad2115122cffdf 353 Gene3D G3DSA:3.40.350.10 1 125 1.4E-38 T 11-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal AFK25_09915 e0b4771e7d6f52ea81ad2115122cffdf 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 207 223 1.0E-6 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFK25_09915 e0b4771e7d6f52ea81ad2115122cffdf 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 305 317 1.0E-6 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFK25_09915 e0b4771e7d6f52ea81ad2115122cffdf 353 PRINTS PR00599 Methionine aminopeptidase-1 signature 185 198 1.0E-6 T 11-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AFK25_09915 e0b4771e7d6f52ea81ad2115122cffdf 353 SUPERFAMILY SSF55920 126 352 8.24E-85 T 11-10-2018 IPR036005 Creatinase/aminopeptidase-like AFK25_09915 e0b4771e7d6f52ea81ad2115122cffdf 353 Pfam PF00557 Metallopeptidase family M24 136 337 1.4E-68 T 11-10-2018 IPR000994 Peptidase M24 AFK25_09915 e0b4771e7d6f52ea81ad2115122cffdf 353 SUPERFAMILY SSF53092 7 127 2.09E-28 T 11-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal AFK25_05540 d4abf1240481535a2c5a7de9bca3a507 110 Gene3D G3DSA:1.10.10.10 1 110 3.5E-37 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_05540 d4abf1240481535a2c5a7de9bca3a507 110 SUPERFAMILY SSF88659 1 100 4.49E-35 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFK25_05540 d4abf1240481535a2c5a7de9bca3a507 110 Hamap MF_00245 UPF0122 protein . 2 103 22.901 T 11-10-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like AFK25_05540 d4abf1240481535a2c5a7de9bca3a507 110 Pfam PF04297 Putative helix-turn-helix protein, YlxM / p13 like 2 92 7.1E-41 T 11-10-2018 IPR007394 Putative helix-turn-helix protein, YlxM/p13-like AFK25_10850 c8f838b38ebc794e7e3118e2ff9ee4b5 245 Gene3D G3DSA:1.10.10.200 1 81 1.6E-35 T 11-10-2018 IPR017856 Integrase-like, N-terminal AFK25_10850 c8f838b38ebc794e7e3118e2ff9ee4b5 245 Gene3D G3DSA:3.30.70.980 134 205 2.5E-57 T 11-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_10850 c8f838b38ebc794e7e3118e2ff9ee4b5 245 Hamap MF_00693 Probable transcriptional regulatory protein YebC [yebC]. 3 241 38.317 T 11-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_10850 c8f838b38ebc794e7e3118e2ff9ee4b5 245 Gene3D G3DSA:3.30.70.980 85 238 2.5E-57 T 11-10-2018 IPR026564 Transcriptional regulator TACO1-like, domain 3 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_10850 c8f838b38ebc794e7e3118e2ff9ee4b5 245 Pfam PF01709 Transcriptional regulator 5 239 9.3E-102 T 11-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_10850 c8f838b38ebc794e7e3118e2ff9ee4b5 245 TIGRFAM TIGR01033 TIGR01033: DNA-binding regulatory protein, YebC/PmpR family 1 239 2.2E-107 T 11-10-2018 IPR002876 Transcriptional regulator TACO1-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_10850 c8f838b38ebc794e7e3118e2ff9ee4b5 245 SUPERFAMILY SSF75625 3 240 2.88E-99 T 11-10-2018 IPR029072 YebC-like Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_08035 60fce5e19cbcad9ad6ccbb5b96ddb56e 289 Gene3D G3DSA:1.10.3470.10 8 275 1.5E-9 T 11-10-2018 IPR037294 ABC transporter, BtuC-like AFK25_08035 60fce5e19cbcad9ad6ccbb5b96ddb56e 289 SUPERFAMILY SSF81345 5 271 2.22E-35 T 11-10-2018 IPR037294 ABC transporter, BtuC-like AFK25_08035 60fce5e19cbcad9ad6ccbb5b96ddb56e 289 Pfam PF00950 ABC 3 transport family 3 273 1.4E-50 T 11-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 AFK25_07675 4dd526f6e704bae0b76f6966ca8e52b6 90 Pfam PF10752 Protein of unknown function (DUF2533) 3 84 4.4E-41 T 11-10-2018 IPR019688 Protein of unknown function DUF2533 AFK25_13320 d7535f09c39702e3a0c7a929e443dd55 72 Gene3D G3DSA:1.20.5.340 12 72 3.2E-5 T 11-10-2018 AFK25_03550 656651c56e2af352b821aa641c77b027 263 Pfam PF01513 ATP-NAD kinase 30 185 6.6E-23 T 11-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFK25_03550 656651c56e2af352b821aa641c77b027 263 Hamap MF_00361 NAD kinase [nadK]. 1 263 23.971 T 11-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFK25_03550 656651c56e2af352b821aa641c77b027 263 Gene3D G3DSA:2.60.200.30 102 240 3.2E-98 T 11-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AFK25_03550 656651c56e2af352b821aa641c77b027 263 Gene3D G3DSA:3.40.50.10330 18 262 3.2E-98 T 11-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 AFK25_03550 656651c56e2af352b821aa641c77b027 263 SUPERFAMILY SSF111331 16 261 2.49E-64 T 11-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily AFK25_01280 9ebea97cfbc7ad1316de2423d132a3c5 129 SUPERFAMILY SSF49764 7 124 2.37E-14 T 11-10-2018 IPR008978 HSP20-like chaperone AFK25_01280 9ebea97cfbc7ad1316de2423d132a3c5 129 Pfam PF00011 Hsp20/alpha crystallin family 33 128 4.5E-7 T 11-10-2018 IPR002068 Alpha crystallin/Hsp20 domain AFK25_01280 9ebea97cfbc7ad1316de2423d132a3c5 129 Gene3D G3DSA:2.60.40.790 2 118 1.4E-12 T 11-10-2018 IPR008978 HSP20-like chaperone AFK25_07470 1298c9443bc6ab74c8c82473e9fa8f30 319 Pfam PF00753 Metallo-beta-lactamase superfamily 29 228 3.2E-22 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_07470 1298c9443bc6ab74c8c82473e9fa8f30 319 Gene3D G3DSA:3.60.15.10 8 280 5.9E-65 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_07470 1298c9443bc6ab74c8c82473e9fa8f30 319 SUPERFAMILY SSF56281 10 281 9.96E-52 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_07470 1298c9443bc6ab74c8c82473e9fa8f30 319 SMART SM00849 23 228 2.2E-29 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_07530 98c6e37acade4365f42320f395e47161 222 Pfam PF05573 NosL 52 176 1.2E-11 T 11-10-2018 IPR008719 Nitrous oxide reductase accessory protein NosL AFK25_07530 98c6e37acade4365f42320f395e47161 222 SUPERFAMILY SSF160387 85 191 6.02E-17 T 11-10-2018 AFK25_13535 66207d83411f7538a6550557f5b37e62 101 Gene3D G3DSA:1.20.5.170 3 98 4.8E-5 T 11-10-2018 AFK25_13535 66207d83411f7538a6550557f5b37e62 101 SUPERFAMILY SSF58113 17 91 3.14E-5 T 11-10-2018 AFK25_13535 66207d83411f7538a6550557f5b37e62 101 Pfam PF07798 Protein of unknown function (DUF1640) 8 72 1.6E-8 T 11-10-2018 IPR024461 Coiled-coil domain-containing protein 90-like AFK25_01780 fc5df0d46351395e9d1aac626d83c93a 390 Gene3D G3DSA:1.20.1250.20 4 189 4.2E-25 T 11-10-2018 AFK25_01780 fc5df0d46351395e9d1aac626d83c93a 390 Gene3D G3DSA:1.20.1250.20 201 382 6.4E-20 T 11-10-2018 AFK25_01780 fc5df0d46351395e9d1aac626d83c93a 390 SUPERFAMILY SSF103473 3 368 6.93E-54 T 11-10-2018 IPR036259 MFS transporter superfamily AFK25_01780 fc5df0d46351395e9d1aac626d83c93a 390 Pfam PF07690 Major Facilitator Superfamily 209 367 3.7E-19 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFK25_01780 fc5df0d46351395e9d1aac626d83c93a 390 Pfam PF07690 Major Facilitator Superfamily 11 203 8.1E-20 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFK25_01945 bc86320b8bee02119a8ecf1cc6f1db1f 334 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 113 332 3.7E-44 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_01945 bc86320b8bee02119a8ecf1cc6f1db1f 334 SUPERFAMILY SSF161098 89 318 1.39E-24 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_12455 e99766ee0c0017bf233b274ae3aae3e7 225 PRINTS PR01837 MgtC/SapB protein signature 93 117 1.8E-40 T 11-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 AFK25_12455 e99766ee0c0017bf233b274ae3aae3e7 225 PRINTS PR01837 MgtC/SapB protein signature 31 49 1.8E-40 T 11-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 AFK25_12455 e99766ee0c0017bf233b274ae3aae3e7 225 PRINTS PR01837 MgtC/SapB protein signature 65 87 1.8E-40 T 11-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 AFK25_12455 e99766ee0c0017bf233b274ae3aae3e7 225 PRINTS PR01837 MgtC/SapB protein signature 12 31 1.8E-40 T 11-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 AFK25_12455 e99766ee0c0017bf233b274ae3aae3e7 225 Pfam PF02308 MgtC family 9 135 1.3E-32 T 11-10-2018 IPR003416 MgtC/SapB/SrpB/YhiD family GO:0016020 AFK25_03930 180b481ae7ee4ea6c9873029e98b6d7e 494 Gene3D G3DSA:1.20.1260.30 1 137 5.6E-34 T 11-10-2018 IPR038333 N6 adenine-specific DNA methyltransferase, N-terminal domain superfamily AFK25_03930 180b481ae7ee4ea6c9873029e98b6d7e 494 Pfam PF12161 HsdM N-terminal domain 9 134 1.5E-29 T 11-10-2018 IPR022749 N6 adenine-specific DNA methyltransferase, N-terminal domain AFK25_03930 180b481ae7ee4ea6c9873029e98b6d7e 494 Gene3D G3DSA:3.40.50.150 147 442 1.8E-112 T 11-10-2018 AFK25_03930 180b481ae7ee4ea6c9873029e98b6d7e 494 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 170 186 1.8E-20 T 11-10-2018 AFK25_03930 180b481ae7ee4ea6c9873029e98b6d7e 494 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 272 284 1.8E-20 T 11-10-2018 AFK25_03930 180b481ae7ee4ea6c9873029e98b6d7e 494 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 308 332 1.8E-20 T 11-10-2018 AFK25_03930 180b481ae7ee4ea6c9873029e98b6d7e 494 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 194 208 1.8E-20 T 11-10-2018 AFK25_03930 180b481ae7ee4ea6c9873029e98b6d7e 494 SUPERFAMILY SSF53335 7 493 1.95E-156 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_03930 180b481ae7ee4ea6c9873029e98b6d7e 494 Pfam PF02384 N-6 DNA Methylase 147 458 2.0E-116 T 11-10-2018 IPR003356 DNA methylase, adenine-specific GO:0003677|GO:0006306|GO:0008170 AFK25_03930 180b481ae7ee4ea6c9873029e98b6d7e 494 TIGRFAM TIGR00497 hsdM: type I restriction-modification system, M subunit 87 465 1.7E-75 T 11-10-2018 IPR004546 Restriction endonuclease, type I, HsdM GO:0003677|GO:0009007|GO:0009307 AFK25_00195 62fa91c0447e5a84cc6ad6b2215d00e4 115 Pfam PF06156 Initiation control protein YabA 2 110 6.8E-38 T 11-10-2018 IPR010377 Initiation control protein YabA GO:0006260 AFK25_00195 62fa91c0447e5a84cc6ad6b2215d00e4 115 PIRSF PIRSF021439 1 115 5.1E-42 T 11-10-2018 IPR010377 Initiation control protein YabA GO:0006260 AFK25_00195 62fa91c0447e5a84cc6ad6b2215d00e4 115 Hamap MF_01159 Initiation-control protein YabA. 1 114 24.596 T 11-10-2018 IPR010377 Initiation control protein YabA GO:0006260 AFK25_00775 308a1c3b940526e02fafbe677ba37d38 130 SUPERFAMILY SSF54211 5 130 3.19E-50 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFK25_00775 308a1c3b940526e02fafbe677ba37d38 130 Hamap MF_00532_B 30S ribosomal protein S9 [rpsI]. 1 130 35.579 T 11-10-2018 IPR023035 Ribosomal protein S9, bacterial/plastid AFK25_00775 308a1c3b940526e02fafbe677ba37d38 130 ProSitePatterns PS00360 Ribosomal protein S9 signature. 69 87 - T 11-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 AFK25_00775 308a1c3b940526e02fafbe677ba37d38 130 Pfam PF00380 Ribosomal protein S9/S16 10 130 1.9E-47 T 11-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 AFK25_00775 308a1c3b940526e02fafbe677ba37d38 130 Gene3D G3DSA:3.30.230.10 1 130 2.9E-53 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFK25_05855 72ee8515ef1d10646e7ec132055af4b4 418 SMART SM00228 183 257 4.8E-8 T 11-10-2018 IPR001478 PDZ domain GO:0005515 AFK25_05855 72ee8515ef1d10646e7ec132055af4b4 418 Pfam PF02163 Peptidase family M50 6 404 5.5E-78 T 11-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 AFK25_05855 72ee8515ef1d10646e7ec132055af4b4 418 Pfam PF13180 PDZ domain 201 265 3.5E-9 T 11-10-2018 IPR001478 PDZ domain GO:0005515 AFK25_05855 72ee8515ef1d10646e7ec132055af4b4 418 Gene3D G3DSA:2.30.42.10 199 287 4.5E-23 T 11-10-2018 AFK25_05855 72ee8515ef1d10646e7ec132055af4b4 418 TIGRFAM TIGR00054 TIGR00054: RIP metalloprotease RseP 2 417 2.3E-110 T 11-10-2018 IPR004387 Peptidase M50, putative membrane-associated zinc metallopeptidase GO:0004222|GO:0006508|GO:0016021 AFK25_05855 72ee8515ef1d10646e7ec132055af4b4 418 SUPERFAMILY SSF50156 172 266 5.52E-20 T 11-10-2018 IPR036034 PDZ superfamily GO:0005515 AFK25_01675 d50be2f15ee2563db794ecd65d595490 229 TIGRFAM TIGR03717 R_switched_YjbE: integral membrane protein, YjbE family 13 186 2.7E-71 T 11-10-2018 IPR022301 Integral membrane protein YjbE AFK25_01675 d50be2f15ee2563db794ecd65d595490 229 Pfam PF03741 Integral membrane protein TerC family 16 185 5.4E-47 T 11-10-2018 IPR005496 Integral membrane protein TerC GO:0016021 AFK25_04730 5031a46530ab29c17f9063e22bdfc5bf 1063 Gene3D G3DSA:3.20.20.80 396 790 3.6E-14 T 11-10-2018 AFK25_04730 5031a46530ab29c17f9063e22bdfc5bf 1063 SUPERFAMILY SSF51445 407 763 4.71E-12 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily AFK25_13135 e210b43cf4da53747dfe36403f1a4581 199 Pfam PF06160 Septation ring formation regulator, EzrA 23 198 4.5E-10 T 11-10-2018 IPR010379 Septation ring formation regulator EzrA GO:0000921|GO:0005940|GO:0016021 AFK25_13135 e210b43cf4da53747dfe36403f1a4581 199 SUPERFAMILY SSF57997 25 195 9.37E-14 T 11-10-2018 AFK25_13135 e210b43cf4da53747dfe36403f1a4581 199 Gene3D G3DSA:1.20.5.340 87 190 3.8E-16 T 11-10-2018 AFK25_13135 e210b43cf4da53747dfe36403f1a4581 199 Gene3D G3DSA:1.20.5.1070 22 86 6.7E-12 T 11-10-2018 AFK25_00885 159b285ace7ce60f344d0026433f2a5a 204 Pfam PF13490 Putative zinc-finger 3 38 1.9E-9 T 11-10-2018 IPR027383 Putative zinc-finger AFK25_00885 159b285ace7ce60f344d0026433f2a5a 204 Gene3D G3DSA:1.10.10.1320 7 93 4.9E-6 T 11-10-2018 AFK25_07875 66259cc39d2de5f61bc95bc834fd47ef 751 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 265 369 7.6E-24 T 11-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II AFK25_07875 66259cc39d2de5f61bc95bc834fd47ef 751 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 18 243 8.4E-57 T 11-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 AFK25_07875 66259cc39d2de5f61bc95bc834fd47ef 751 Gene3D G3DSA:3.40.50.970 526 748 8.5E-45 T 11-10-2018 AFK25_07875 66259cc39d2de5f61bc95bc834fd47ef 751 Gene3D G3DSA:3.40.50.920 256 395 5.5E-35 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFK25_07875 66259cc39d2de5f61bc95bc834fd47ef 751 SUPERFAMILY SSF52922 256 392 1.71E-29 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFK25_07875 66259cc39d2de5f61bc95bc834fd47ef 751 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 482 648 1.1E-9 T 11-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFK25_07875 66259cc39d2de5f61bc95bc834fd47ef 751 SUPERFAMILY SSF52518 386 748 2.29E-58 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold AFK25_07875 66259cc39d2de5f61bc95bc834fd47ef 751 SUPERFAMILY SSF52518 7 254 2.19E-55 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold AFK25_07875 66259cc39d2de5f61bc95bc834fd47ef 751 Gene3D G3DSA:3.40.50.970 4 255 2.2E-75 T 11-10-2018 AFK25_10650 944c7d1ad070565194fd4da3308f6013 417 Gene3D G3DSA:2.40.30.10 329 416 1.8E-38 T 11-10-2018 AFK25_10650 944c7d1ad070565194fd4da3308f6013 417 ProSitePatterns PS01276 Peptidase family U32 signature. 174 192 - T 11-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 AFK25_10650 944c7d1ad070565194fd4da3308f6013 417 Pfam PF01136 Peptidase family U32 90 318 1.7E-87 T 11-10-2018 IPR001539 Peptidase U32 GO:0006508|GO:0008233 AFK25_10650 944c7d1ad070565194fd4da3308f6013 417 Pfam PF16325 Peptidase family U32 C-terminal domain 333 414 1.8E-26 T 11-10-2018 IPR032525 Peptidase family U32, C-terminal AFK25_11210 ec04ffbaa00e90187e62d32de7aa5240 203 Gene3D G3DSA:3.90.950.10 1 196 1.6E-78 T 11-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFK25_11210 ec04ffbaa00e90187e62d32de7aa5240 203 SUPERFAMILY SSF52972 2 193 1.7E-71 T 11-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AFK25_11210 ec04ffbaa00e90187e62d32de7aa5240 203 Pfam PF01725 Ham1 family 5 190 2.4E-61 T 11-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 AFK25_11210 ec04ffbaa00e90187e62d32de7aa5240 203 Hamap MF_01405 dITP/XTP pyrophosphatase. 2 195 49.271 T 11-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 AFK25_11210 ec04ffbaa00e90187e62d32de7aa5240 203 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 4 192 2.0E-66 T 11-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 AFK25_08665 700e1ea288ef867b00df3b51c67c6c65 141 SUPERFAMILY SSF49764 6 139 5.08E-38 T 11-10-2018 IPR008978 HSP20-like chaperone AFK25_08665 700e1ea288ef867b00df3b51c67c6c65 141 Gene3D G3DSA:2.60.40.790 1 140 6.1E-39 T 11-10-2018 IPR008978 HSP20-like chaperone AFK25_08665 700e1ea288ef867b00df3b51c67c6c65 141 Pfam PF00011 Hsp20/alpha crystallin family 38 139 8.5E-22 T 11-10-2018 IPR002068 Alpha crystallin/Hsp20 domain AFK25_03895 ebaec768047f7e47c54bb707ed7e5d9f 84 Pfam PF01610 Transposase 1 70 5.1E-24 T 11-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain AFK25_07025 927ffdb1ba55151522b82dd74efa6e39 435 SMART SM00388 205 271 2.1E-12 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_07025 927ffdb1ba55151522b82dd74efa6e39 435 Pfam PF00512 His Kinase A (phospho-acceptor) domain 207 267 4.3E-12 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_07025 927ffdb1ba55151522b82dd74efa6e39 435 Gene3D G3DSA:1.10.287.130 209 268 2.0E-67 T 11-10-2018 AFK25_07025 927ffdb1ba55151522b82dd74efa6e39 435 SUPERFAMILY SSF47384 200 268 9.61E-14 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFK25_07025 927ffdb1ba55151522b82dd74efa6e39 435 SMART SM00387 311 418 8.6E-26 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_07025 927ffdb1ba55151522b82dd74efa6e39 435 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 313 415 5.5E-21 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_07025 927ffdb1ba55151522b82dd74efa6e39 435 Pfam PF07694 5TMR of 5TMR-LYT 28 187 2.3E-17 T 11-10-2018 IPR011620 Signal transduction histidine kinase, 5TM receptor LytS, transmembrane region GO:0000155|GO:0000160|GO:0004673|GO:0016021|GO:0071555 AFK25_07025 927ffdb1ba55151522b82dd74efa6e39 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 378 396 6.9E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_07025 927ffdb1ba55151522b82dd74efa6e39 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 366 376 6.9E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_07025 927ffdb1ba55151522b82dd74efa6e39 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 402 415 6.9E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_07025 927ffdb1ba55151522b82dd74efa6e39 435 PRINTS PR00344 Bacterial sensor protein C-terminal signature 348 362 6.9E-13 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_07025 927ffdb1ba55151522b82dd74efa6e39 435 Gene3D G3DSA:3.30.565.10 269 415 2.0E-67 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_07025 927ffdb1ba55151522b82dd74efa6e39 435 SUPERFAMILY SSF55874 272 416 9.43E-37 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_09650 d4feaeae22d65b7b0254daf2d97e210a 105 SUPERFAMILY SSF89360 3 103 4.19E-27 T 11-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 AFK25_09650 d4feaeae22d65b7b0254daf2d97e210a 105 Gene3D G3DSA:2.60.300.12 1 105 1.6E-6 T 11-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 AFK25_09650 d4feaeae22d65b7b0254daf2d97e210a 105 Pfam PF01521 Iron-sulphur cluster biosynthesis 3 102 8.9E-26 T 11-10-2018 IPR000361 FeS cluster biogenesis Reactome: R-HSA-1362409 AFK25_02335 76d6a7a74727008e556ee8ba2255abb7 244 Pfam PF03374 Phage antirepressor protein KilAC domain 143 240 4.5E-23 T 11-10-2018 IPR005039 Antirepressor protein, C-terminal GO:0003677 AFK25_02335 76d6a7a74727008e556ee8ba2255abb7 244 Pfam PF02498 BRO family, N-terminal domain 14 100 2.1E-26 T 11-10-2018 IPR003497 BRO N-terminal domain AFK25_02335 76d6a7a74727008e556ee8ba2255abb7 244 SMART SM01040 14 100 4.0E-39 T 11-10-2018 IPR003497 BRO N-terminal domain AFK25_13875 6e7b21975f2aab7d299ded5ae7e787df 75 Pfam PF09527 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter 13 64 1.8E-17 T 11-10-2018 IPR032820 Putative F0F1-ATPase subunit, Ca2+/Mg2+ transporter AFK25_03685 6df3fb657e12570ae1385aaa5e94595e 105 Pfam PF00085 Thioredoxin 7 101 4.2E-18 T 11-10-2018 IPR013766 Thioredoxin domain GO:0045454 AFK25_03685 6df3fb657e12570ae1385aaa5e94595e 105 Gene3D G3DSA:3.40.30.10 1 104 4.0E-26 T 11-10-2018 AFK25_03685 6df3fb657e12570ae1385aaa5e94595e 105 SUPERFAMILY SSF52833 4 102 3.18E-27 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_07760 6dc42b5dca17b179546dd399197e33e7 97 Pfam PF01740 STAS domain 6 94 2.2E-8 T 11-10-2018 IPR002645 STAS domain AFK25_07760 6dc42b5dca17b179546dd399197e33e7 97 Gene3D G3DSA:3.30.750.24 1 97 6.4E-13 T 11-10-2018 IPR036513 STAS domain superfamily AFK25_07760 6dc42b5dca17b179546dd399197e33e7 97 SUPERFAMILY SSF52091 3 96 4.71E-14 T 11-10-2018 IPR036513 STAS domain superfamily AFK25_09715 6902fdcb8bcca021de9f99fac789a953 137 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 5 132 9.2E-49 T 11-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 AFK25_09715 6902fdcb8bcca021de9f99fac789a953 137 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 7 117 5.5E-25 T 11-10-2018 AFK25_09715 6902fdcb8bcca021de9f99fac789a953 137 SUPERFAMILY SSF54593 2 135 1.48E-35 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFK25_09715 6902fdcb8bcca021de9f99fac789a953 137 Gene3D G3DSA:3.10.180.10 1 134 7.3E-45 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFK25_13325 c9f1b82b69a4dd842bc49214efb7f023 448 Pfam PF08486 Stage II sporulation protein 134 216 1.6E-23 T 11-10-2018 IPR013693 Sporulation stage II protein D, amidase enhancer LytB N-terminal AFK25_13325 c9f1b82b69a4dd842bc49214efb7f023 448 TIGRFAM TIGR02669 SpoIID_LytB: SpoIID/LytB domain 136 445 6.1E-70 T 11-10-2018 IPR013486 Sporulation stage II protein D, amidase enhancer LytB GO:0030435 AFK25_09750 9c83cf188d5ec653bcf742e01ec22a63 327 Gene3D G3DSA:3.40.50.970 1 192 2.4E-93 T 11-10-2018 AFK25_09750 9c83cf188d5ec653bcf742e01ec22a63 327 Pfam PF02780 Transketolase, C-terminal domain 194 317 1.9E-41 T 11-10-2018 IPR033248 Transketolase, C-terminal domain AFK25_09750 9c83cf188d5ec653bcf742e01ec22a63 327 SMART SM00861 4 179 1.0E-73 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFK25_09750 9c83cf188d5ec653bcf742e01ec22a63 327 SUPERFAMILY SSF52518 2 204 6.38E-75 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold AFK25_09750 9c83cf188d5ec653bcf742e01ec22a63 327 SUPERFAMILY SSF52922 188 325 5.89E-41 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFK25_09750 9c83cf188d5ec653bcf742e01ec22a63 327 Pfam PF02779 Transketolase, pyrimidine binding domain 4 178 1.0E-53 T 11-10-2018 IPR005475 Transketolase-like, pyrimidine-binding domain AFK25_09750 9c83cf188d5ec653bcf742e01ec22a63 327 Gene3D G3DSA:3.40.50.920 193 327 1.0E-43 T 11-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AFK25_01400 7f0614bd67935abe61ba16f91e7e0974 484 PRINTS PR00175 Sodium/alanine symporter signature 204 223 4.4E-59 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_01400 7f0614bd67935abe61ba16f91e7e0974 484 PRINTS PR00175 Sodium/alanine symporter signature 86 108 4.4E-59 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_01400 7f0614bd67935abe61ba16f91e7e0974 484 PRINTS PR00175 Sodium/alanine symporter signature 295 313 4.4E-59 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_01400 7f0614bd67935abe61ba16f91e7e0974 484 PRINTS PR00175 Sodium/alanine symporter signature 416 436 4.4E-59 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_01400 7f0614bd67935abe61ba16f91e7e0974 484 PRINTS PR00175 Sodium/alanine symporter signature 176 194 4.4E-59 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_01400 7f0614bd67935abe61ba16f91e7e0974 484 PRINTS PR00175 Sodium/alanine symporter signature 353 375 4.4E-59 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_01400 7f0614bd67935abe61ba16f91e7e0974 484 ProSitePatterns PS00873 Sodium:alanine symporter family signature. 86 101 - T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_01400 7f0614bd67935abe61ba16f91e7e0974 484 Pfam PF01235 Sodium:alanine symporter family 49 459 1.3E-159 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_01400 7f0614bd67935abe61ba16f91e7e0974 484 TIGRFAM TIGR00835 agcS: amino acid carrier protein 13 447 4.0E-149 T 11-10-2018 IPR001463 Sodium:alanine symporter GO:0006814|GO:0015655|GO:0016020|GO:0032328 AFK25_05180 3fc9f8384dfea0b70a7ab11681ad4ff0 536 Hamap MF_01867 Putative cysteine ligase BshC [bshC]. 1 536 31.558 T 11-10-2018 IPR011199 Bacillithiol biosynthesis BshC AFK25_05180 3fc9f8384dfea0b70a7ab11681ad4ff0 536 Pfam PF10079 Bacillithiol biosynthesis BshC 1 533 3.4E-175 T 11-10-2018 IPR011199 Bacillithiol biosynthesis BshC AFK25_05180 3fc9f8384dfea0b70a7ab11681ad4ff0 536 TIGRFAM TIGR03998 thiol_BshC: bacillithiol biosynthesis cysteine-adding enzyme BshC 11 534 3.8E-179 T 11-10-2018 IPR011199 Bacillithiol biosynthesis BshC AFK25_05180 3fc9f8384dfea0b70a7ab11681ad4ff0 536 PIRSF PIRSF012535 1 536 7.3E-184 T 11-10-2018 IPR011199 Bacillithiol biosynthesis BshC AFK25_05420 6b9ccbdece28dae0a6fbd4bd53a9c801 157 SUPERFAMILY SSF56420 2 148 2.36E-55 T 11-10-2018 IPR036821 Peptide deformylase superfamily AFK25_05420 6b9ccbdece28dae0a6fbd4bd53a9c801 157 Hamap MF_00163 Peptide deformylase [def]. 2 157 27.936 T 11-10-2018 IPR023635 Peptide deformylase AFK25_05420 6b9ccbdece28dae0a6fbd4bd53a9c801 157 Gene3D G3DSA:3.90.45.10 1 156 9.8E-60 T 11-10-2018 IPR036821 Peptide deformylase superfamily AFK25_05420 6b9ccbdece28dae0a6fbd4bd53a9c801 157 PIRSF PIRSF004749 1 151 1.2E-49 T 11-10-2018 IPR023635 Peptide deformylase AFK25_05420 6b9ccbdece28dae0a6fbd4bd53a9c801 157 Pfam PF01327 Polypeptide deformylase 4 146 1.8E-47 T 11-10-2018 IPR023635 Peptide deformylase AFK25_05420 6b9ccbdece28dae0a6fbd4bd53a9c801 157 TIGRFAM TIGR00079 pept_deformyl: peptide deformylase 5 151 2.2E-51 T 11-10-2018 IPR023635 Peptide deformylase AFK25_05420 6b9ccbdece28dae0a6fbd4bd53a9c801 157 PRINTS PR01576 Peptide deformylase signature 119 148 5.4E-35 T 11-10-2018 IPR023635 Peptide deformylase AFK25_05420 6b9ccbdece28dae0a6fbd4bd53a9c801 157 PRINTS PR01576 Peptide deformylase signature 88 99 5.4E-35 T 11-10-2018 IPR023635 Peptide deformylase AFK25_05420 6b9ccbdece28dae0a6fbd4bd53a9c801 157 PRINTS PR01576 Peptide deformylase signature 33 62 5.4E-35 T 11-10-2018 IPR023635 Peptide deformylase AFK25_05420 6b9ccbdece28dae0a6fbd4bd53a9c801 157 PRINTS PR01576 Peptide deformylase signature 100 118 5.4E-35 T 11-10-2018 IPR023635 Peptide deformylase AFK25_11670 8ba818e9917d3ce1f7d01577b10bcbf0 112 Pfam PF14034 Sporulation protein YtrH 11 108 5.2E-41 T 11-10-2018 IPR025689 Sporulation protein YtrH AFK25_12920 ecc538bc1abee7a8a7da60996fc8c1e3 343 SUPERFAMILY SSF46785 19 83 3.27E-9 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_12920 ecc538bc1abee7a8a7da60996fc8c1e3 343 Pfam PF04198 Putative sugar-binding domain 91 337 3.0E-73 T 11-10-2018 IPR007324 Sugar-binding domain, putative GO:0030246 AFK25_12920 ecc538bc1abee7a8a7da60996fc8c1e3 343 Gene3D G3DSA:3.40.50.1360 91 340 1.2E-85 T 11-10-2018 AFK25_12920 ecc538bc1abee7a8a7da60996fc8c1e3 343 SUPERFAMILY SSF100950 91 337 7.18E-71 T 11-10-2018 IPR037171 NagB/RpiA transferase-like AFK25_12920 ecc538bc1abee7a8a7da60996fc8c1e3 343 Gene3D G3DSA:1.10.10.10 19 90 2.9E-15 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_08960 3c439e7c92c659b6a9cfb3e63722376c 90 SMART SM00411 1 90 5.0E-54 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFK25_08960 3c439e7c92c659b6a9cfb3e63722376c 90 ProSitePatterns PS00045 Bacterial histone-like DNA-binding proteins signature. 46 65 - T 11-10-2018 IPR020816 Histone-like DNA-binding protein, conserved site GO:0003677 AFK25_08960 3c439e7c92c659b6a9cfb3e63722376c 90 PRINTS PR01727 Prokaryotic integration host factor signature 40 55 1.7E-22 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFK25_08960 3c439e7c92c659b6a9cfb3e63722376c 90 PRINTS PR01727 Prokaryotic integration host factor signature 58 71 1.7E-22 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFK25_08960 3c439e7c92c659b6a9cfb3e63722376c 90 PRINTS PR01727 Prokaryotic integration host factor signature 74 88 1.7E-22 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFK25_08960 3c439e7c92c659b6a9cfb3e63722376c 90 Pfam PF00216 Bacterial DNA-binding protein 1 90 2.1E-39 T 11-10-2018 IPR000119 Histone-like DNA-binding protein GO:0003677 AFK25_08960 3c439e7c92c659b6a9cfb3e63722376c 90 SUPERFAMILY SSF47729 1 90 4.27E-37 T 11-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFK25_08960 3c439e7c92c659b6a9cfb3e63722376c 90 Gene3D G3DSA:4.10.520.10 1 90 4.5E-43 T 11-10-2018 IPR010992 Integration host factor (IHF)-like DNA-binding domain superfamily GO:0003677 AFK25_13975 c8bd4013c0247543f4dc13f03005834c 119 SMART SM00448 3 114 8.3E-32 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_13975 c8bd4013c0247543f4dc13f03005834c 119 Pfam PF00072 Response regulator receiver domain 5 115 3.0E-30 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_13975 c8bd4013c0247543f4dc13f03005834c 119 SUPERFAMILY SSF52172 4 118 9.68E-37 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_13975 c8bd4013c0247543f4dc13f03005834c 119 Gene3D G3DSA:3.40.50.2300 1 119 1.0E-41 T 11-10-2018 AFK25_06140 ae34c430586a9657043a2406c129db33 131 Pfam PF01909 Nucleotidyltransferase domain 6 89 3.1E-9 T 11-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AFK25_06140 ae34c430586a9657043a2406c129db33 131 Gene3D G3DSA:3.30.460.10 1 101 5.5E-21 T 11-10-2018 AFK25_06140 ae34c430586a9657043a2406c129db33 131 SUPERFAMILY SSF81301 6 101 1.51E-16 T 11-10-2018 AFK25_11125 cd462811252fa7ac3d9621c9baf823d8 157 ProDom PD104119 YSXD OB2071 ORFY 1 152 2.0E-11 T 11-10-2018 AFK25_01920 79063791a5a4b5a00b499667bd0baabd 49 TIGRFAM TIGR01442 SASP_gamma: small, acid-soluble spore protein, gamma-type 9 48 3.6E-12 T 11-10-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 AFK25_01920 79063791a5a4b5a00b499667bd0baabd 49 Pfam PF04259 Small, acid-soluble spore protein, gamma-type 9 49 5.7E-12 T 11-10-2018 IPR006341 Acid-soluble spore protein, gamma-type GO:0030435 AFK25_09050 8e8766979ebcf986a82f7b5f6a86b02b 454 Gene3D G3DSA:3.40.640.10 68 344 2.5E-164 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_09050 8e8766979ebcf986a82f7b5f6a86b02b 454 Hamap MF_00834 Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [bioA]. 8 449 53.476 T 11-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 AFK25_09050 8e8766979ebcf986a82f7b5f6a86b02b 454 Gene3D G3DSA:3.90.1150.10 16 446 2.5E-164 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_09050 8e8766979ebcf986a82f7b5f6a86b02b 454 TIGRFAM TIGR00508 bioA: adenosylmethionine-8-amino-7-oxononanoate transaminase 19 446 3.3E-166 T 11-10-2018 IPR005815 Adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA GO:0004015|GO:0009102 KEGG: 00780+2.6.1.62 AFK25_09050 8e8766979ebcf986a82f7b5f6a86b02b 454 PIRSF PIRSF000521 22 448 6.3E-33 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFK25_09050 8e8766979ebcf986a82f7b5f6a86b02b 454 Pfam PF00202 Aminotransferase class-III 28 446 2.7E-117 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFK25_09050 8e8766979ebcf986a82f7b5f6a86b02b 454 SUPERFAMILY SSF53383 16 446 2.62E-129 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_09050 8e8766979ebcf986a82f7b5f6a86b02b 454 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 254 291 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFK25_06695 d2fb4c3132f1059334c55232d2e9b677 426 SUPERFAMILY SSF63411 14 219 1.92E-41 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFK25_06695 d2fb4c3132f1059334c55232d2e9b677 426 Pfam PF05193 Peptidase M16 inactive domain 182 359 4.6E-15 T 11-10-2018 IPR007863 Peptidase M16, C-terminal AFK25_06695 d2fb4c3132f1059334c55232d2e9b677 426 SUPERFAMILY SSF63411 240 422 7.67E-18 T 11-10-2018 IPR011249 Metalloenzyme, LuxS/M16 peptidase-like GO:0003824|GO:0046872 AFK25_06695 d2fb4c3132f1059334c55232d2e9b677 426 Pfam PF00675 Insulinase (Peptidase family M16) 63 173 1.5E-17 T 11-10-2018 IPR011765 Peptidase M16, N-terminal AFK25_06695 d2fb4c3132f1059334c55232d2e9b677 426 Gene3D G3DSA:3.30.830.10 8 236 7.8E-59 T 11-10-2018 AFK25_06695 d2fb4c3132f1059334c55232d2e9b677 426 Gene3D G3DSA:3.30.830.10 238 424 2.9E-41 T 11-10-2018 AFK25_06960 464679aea874384af07b591de4230b3b 62 Pfam PF10782 Zinc-finger 1 57 1.0E-25 T 11-10-2018 IPR019718 Protein of unknown function DUF2602 AFK25_13480 3fb60e3e0d765cb27858d4e4e4181e03 73 SUPERFAMILY SSF143422 1 70 1.09E-9 T 11-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 AFK25_13480 3fb60e3e0d765cb27858d4e4e4181e03 73 Pfam PF01797 Transposase IS200 like 1 72 1.3E-6 T 11-10-2018 IPR002686 Transposase IS200-like GO:0003677|GO:0004803|GO:0006313 AFK25_13480 3fb60e3e0d765cb27858d4e4e4181e03 73 Gene3D G3DSA:3.30.70.1290 1 70 1.2E-11 T 11-10-2018 IPR036515 Transposase IS200-like superfamily GO:0003677|GO:0004803|GO:0006313 AFK25_05410 398ef79ae68b4d33902cf9466e0c6e27 400 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 2 392 4.4E-160 T 11-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 AFK25_05410 398ef79ae68b4d33902cf9466e0c6e27 400 Gene3D G3DSA:3.40.50.10300 185 399 6.4E-88 T 11-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AFK25_05410 398ef79ae68b4d33902cf9466e0c6e27 400 SUPERFAMILY SSF52507 1 178 9.16E-65 T 11-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AFK25_05410 398ef79ae68b4d33902cf9466e0c6e27 400 Pfam PF02441 Flavoprotein 5 178 3.6E-49 T 11-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AFK25_05410 398ef79ae68b4d33902cf9466e0c6e27 400 SUPERFAMILY SSF102645 183 395 1.57E-78 T 11-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AFK25_05410 398ef79ae68b4d33902cf9466e0c6e27 400 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 185 367 8.1E-76 T 11-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AFK25_05410 398ef79ae68b4d33902cf9466e0c6e27 400 Gene3D G3DSA:3.40.50.1950 1 184 3.3E-65 T 11-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AFK25_07145 ac9d3cbc1266566b5a0d1a0c25b3be79 75 SUPERFAMILY SSF159127 1 73 4.97E-24 T 11-10-2018 IPR037254 HupF/HypC superfamily AFK25_07145 ac9d3cbc1266566b5a0d1a0c25b3be79 75 Pfam PF01455 HupF/HypC family 1 64 3.2E-23 T 11-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFK25_07145 ac9d3cbc1266566b5a0d1a0c25b3be79 75 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 73 1.1E-24 T 11-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFK25_07145 ac9d3cbc1266566b5a0d1a0c25b3be79 75 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 1.1E-9 T 11-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFK25_07145 ac9d3cbc1266566b5a0d1a0c25b3be79 75 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 38 54 1.1E-9 T 11-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFK25_07145 ac9d3cbc1266566b5a0d1a0c25b3be79 75 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 17 33 1.1E-9 T 11-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AFK25_07145 ac9d3cbc1266566b5a0d1a0c25b3be79 75 Gene3D G3DSA:2.40.50.970 1 73 2.5E-25 T 11-10-2018 IPR037254 HupF/HypC superfamily AFK25_07145 ac9d3cbc1266566b5a0d1a0c25b3be79 75 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 11-10-2018 IPR019812 Hydrogenase assembly chaperone, conserved site AFK25_08535 c5c96fe7a112089f14abb7971ec3c90d 351 Gene3D G3DSA:1.25.40.10 21 139 1.2E-10 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_08535 c5c96fe7a112089f14abb7971ec3c90d 351 Pfam PF07719 Tetratricopeptide repeat 104 135 2.1E-5 T 11-10-2018 IPR013105 Tetratricopeptide repeat 2 AFK25_08535 c5c96fe7a112089f14abb7971ec3c90d 351 SMART SM00028 103 136 6.9E-4 T 11-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AFK25_08535 c5c96fe7a112089f14abb7971ec3c90d 351 SUPERFAMILY SSF48452 84 159 1.69E-10 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_13885 4c7918a30978ceb6bd83873adc9f8c53 209 Gene3D G3DSA:3.40.50.2020 1 209 1.2E-84 T 11-10-2018 AFK25_13885 4c7918a30978ceb6bd83873adc9f8c53 209 Pfam PF14681 Uracil phosphoribosyltransferase 6 208 6.3E-76 T 11-10-2018 AFK25_13885 4c7918a30978ceb6bd83873adc9f8c53 209 SUPERFAMILY SSF53271 4 207 2.88E-74 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like AFK25_13885 4c7918a30978ceb6bd83873adc9f8c53 209 Hamap MF_01218_B Uracil phosphoribosyltransferase [upp]. 3 209 48.948 T 11-10-2018 IPR034332 Uracil phosphoribosyltransferase, bacterial-type KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 AFK25_13885 4c7918a30978ceb6bd83873adc9f8c53 209 TIGRFAM TIGR01091 upp: uracil phosphoribosyltransferase 3 209 1.2E-94 T 11-10-2018 IPR005765 Uracil phosphoribosyl transferase GO:0004845|GO:0006223 KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 AFK25_06485 1f27b5d816a32440a00ba0eeafa9bd13 145 Pfam PF00359 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 5 143 1.0E-36 T 11-10-2018 IPR002178 PTS EIIA type-2 domain AFK25_06485 1f27b5d816a32440a00ba0eeafa9bd13 145 SUPERFAMILY SSF55804 6 143 1.31E-41 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 AFK25_06485 1f27b5d816a32440a00ba0eeafa9bd13 145 Gene3D G3DSA:3.40.930.10 2 143 1.4E-45 T 11-10-2018 IPR016152 Phosphotransferase/anion transporter Reactome: R-HSA-425381 AFK25_06485 1f27b5d816a32440a00ba0eeafa9bd13 145 ProSitePatterns PS00372 PTS EIIA domains phosphorylation site signature 2. 49 65 - T 11-10-2018 IPR002178 PTS EIIA type-2 domain AFK25_00290 3d96c3a847ec3c4a065b6e055e4aff9c 76 Pfam PF10955 Protein of unknown function (DUF2757) 1 76 1.9E-35 T 11-10-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 AFK25_00290 3d96c3a847ec3c4a065b6e055e4aff9c 76 ProDom PD057826 YABK 4 75 3.0E-25 T 11-10-2018 IPR020115 Anti-sigma-F factor Fin GO:0010468 AFK25_13860 fda8f947dac603618353e4766941c8e4 70 Gene3D G3DSA:1.20.20.10 1 70 3.3E-30 T 11-10-2018 IPR038662 F1F0 ATP synthase subunit C superfamily Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13860 fda8f947dac603618353e4766941c8e4 70 PRINTS PR00124 ATP synthase C subunit signature 43 68 5.4E-20 T 11-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13860 fda8f947dac603618353e4766941c8e4 70 PRINTS PR00124 ATP synthase C subunit signature 26 41 5.4E-20 T 11-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13860 fda8f947dac603618353e4766941c8e4 70 PRINTS PR00124 ATP synthase C subunit signature 5 24 5.4E-20 T 11-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13860 fda8f947dac603618353e4766941c8e4 70 TIGRFAM TIGR01260 ATP_synt_c: ATP synthase F0, C subunit 13 67 1.0E-24 T 11-10-2018 IPR005953 ATP synthase, F0 complex, subunit C, bacterial/chloroplast GO:0015078|GO:0015986|GO:0045263 AFK25_13860 fda8f947dac603618353e4766941c8e4 70 ProSitePatterns PS00605 ATP synthase c subunit signature. 33 54 - T 11-10-2018 IPR020537 ATP synthase, F0 complex, subunit C, DCCD-binding site Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13860 fda8f947dac603618353e4766941c8e4 70 Hamap MF_01396 ATP synthase subunit c [atpH]. 3 68 16.434 T 11-10-2018 IPR000454 ATP synthase, F0 complex, subunit C GO:0015078|GO:0015986|GO:0045263 Reactome: R-HSA-163210|Reactome: R-HSA-8949613 AFK25_13860 fda8f947dac603618353e4766941c8e4 70 Pfam PF00137 ATP synthase subunit C 4 66 2.6E-15 T 11-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 AFK25_13860 fda8f947dac603618353e4766941c8e4 70 SUPERFAMILY SSF81333 3 67 6.41E-20 T 11-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily AFK25_04620 31b7ca8612288dfbc301566c67dfd7e0 113 TIGRFAM TIGR01300 CPA3_mnhG_phaG: monovalent cation/proton antiporter, MnhG/PhaG subunit 10 105 1.2E-30 T 11-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 AFK25_04620 31b7ca8612288dfbc301566c67dfd7e0 113 Pfam PF03334 Na+/H+ antiporter subunit 10 91 8.9E-28 T 11-10-2018 IPR005133 Na+/H+ antiporter subunit G GO:0005451|GO:0015672|GO:1902600 AFK25_06000 7779deb423bdffc5e6691a847de416e8 348 Pfam PF02653 Branched-chain amino acid transport system / permease component 52 330 1.3E-48 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFK25_08170 b75f8c7bbfc63d8d0b4a82b63f7aa0d9 316 Gene3D G3DSA:3.40.50.1980 36 142 6.8E-36 T 11-10-2018 AFK25_08170 b75f8c7bbfc63d8d0b4a82b63f7aa0d9 316 SUPERFAMILY SSF53807 39 309 5.45E-70 T 11-10-2018 AFK25_08170 b75f8c7bbfc63d8d0b4a82b63f7aa0d9 316 Pfam PF01497 Periplasmic binding protein 56 288 1.5E-32 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain AFK25_08170 b75f8c7bbfc63d8d0b4a82b63f7aa0d9 316 Gene3D G3DSA:3.40.50.1980 143 316 1.1E-65 T 11-10-2018 AFK25_13690 081a87a55a4cca8a526000462b2e83d1 123 Gene3D G3DSA:3.10.180.10 9 121 9.8E-33 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFK25_13690 081a87a55a4cca8a526000462b2e83d1 123 SUPERFAMILY SSF54593 8 119 8.32E-21 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFK25_13690 081a87a55a4cca8a526000462b2e83d1 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 118 1.5E-6 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFK25_01030 ade519a8fed689691e40bdd4eccaec0e 260 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 259 8.8E-74 T 11-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AFK25_01030 ade519a8fed689691e40bdd4eccaec0e 260 SUPERFAMILY SSF52096 1 259 4.39E-90 T 11-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AFK25_01030 ade519a8fed689691e40bdd4eccaec0e 260 Gene3D G3DSA:3.90.226.10 2 202 1.2E-75 T 11-10-2018 AFK25_01030 ade519a8fed689691e40bdd4eccaec0e 260 Gene3D G3DSA:1.10.12.10 203 260 5.4E-26 T 11-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AFK25_03465 f9a28c4ab4265f9f9df73801898c7fd1 309 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 112 303 1.2E-37 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_03465 f9a28c4ab4265f9f9df73801898c7fd1 309 SUPERFAMILY SSF161098 91 291 6.98E-17 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_03465 f9a28c4ab4265f9f9df73801898c7fd1 309 Gene3D G3DSA:1.10.3720.10 84 299 6.8E-20 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_10615 669426f673f82b2e2d65758fff8002ce 232 Gene3D G3DSA:3.40.50.1580 1 232 8.1E-75 T 11-10-2018 AFK25_10615 669426f673f82b2e2d65758fff8002ce 232 Pfam PF01048 Phosphorylase superfamily 2 223 3.4E-54 T 11-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 AFK25_10615 669426f673f82b2e2d65758fff8002ce 232 TIGRFAM TIGR01704 MTA/SAH-Nsdase: MTA/SAH nucleosidase 2 229 9.1E-111 T 11-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 AFK25_10615 669426f673f82b2e2d65758fff8002ce 232 Hamap MF_01684 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase [mtnN]. 2 230 48.353 T 11-10-2018 IPR010049 MTA/SAH nucleosidase GO:0008782|GO:0008930|GO:0009164|GO:0019509 KEGG: 00270+3.2.2.9|MetaCyc: PWY-6151|MetaCyc: PWY-6153|MetaCyc: PWY-6154 AFK25_10615 669426f673f82b2e2d65758fff8002ce 232 SUPERFAMILY SSF53167 1 230 2.09E-74 T 11-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 AFK25_11565 40645ee504dd0d452f5673456122b27d 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 109 122 2.6E-40 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_11565 40645ee504dd0d452f5673456122b27d 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 172 188 2.6E-40 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_11565 40645ee504dd0d452f5673456122b27d 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 228 245 2.6E-40 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_11565 40645ee504dd0d452f5673456122b27d 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 145 163 2.6E-40 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_11565 40645ee504dd0d452f5673456122b27d 342 PRINTS PR00078 Glyceraldehyde-3-phosphate dehydrogenase signature 268 283 2.6E-40 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_11565 40645ee504dd0d452f5673456122b27d 342 Gene3D G3DSA:3.30.360.10 150 314 3.2E-150 T 11-10-2018 AFK25_11565 40645ee504dd0d452f5673456122b27d 342 SUPERFAMILY SSF51735 1 178 2.43E-58 T 11-10-2018 IPR036291 NAD(P)-binding domain superfamily AFK25_11565 40645ee504dd0d452f5673456122b27d 342 Gene3D G3DSA:3.40.50.720 4 327 3.2E-150 T 11-10-2018 AFK25_11565 40645ee504dd0d452f5673456122b27d 342 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 156 312 3.3E-69 T 11-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_11565 40645ee504dd0d452f5673456122b27d 342 Pfam PF00044 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain 4 102 2.1E-36 T 11-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_11565 40645ee504dd0d452f5673456122b27d 342 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 149 156 - T 11-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_11565 40645ee504dd0d452f5673456122b27d 342 SUPERFAMILY SSF55347 151 313 1.04E-72 T 11-10-2018 AFK25_11565 40645ee504dd0d452f5673456122b27d 342 TIGRFAM TIGR01534 GAPDH-I: glyceraldehyde-3-phosphate dehydrogenase, type I 4 324 6.8E-132 T 11-10-2018 IPR006424 Glyceraldehyde-3-phosphate dehydrogenase, type I GO:0006006|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.12|KEGG: 00710+1.2.1.12|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_11565 40645ee504dd0d452f5673456122b27d 342 PIRSF PIRSF000149 1 333 1.5E-138 T 11-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_11565 40645ee504dd0d452f5673456122b27d 342 SMART SM00846 3 151 5.1E-85 T 11-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AFK25_04950 47e5851e27ef383f091ce93f5fe1036b 101 Pfam PF14036 YlaH-like protein 18 93 5.9E-32 T 11-10-2018 IPR025620 YlaH-like protein AFK25_09510 bbdc6db8ca69ca5dd633b607cf08d7ea 337 Pfam PF00899 ThiF family 5 242 5.7E-59 T 11-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 AFK25_09510 bbdc6db8ca69ca5dd633b607cf08d7ea 337 SUPERFAMILY SSF69572 2 326 1.29E-84 T 11-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 AFK25_09510 bbdc6db8ca69ca5dd633b607cf08d7ea 337 Gene3D G3DSA:3.40.50.720 1 251 3.7E-74 T 11-10-2018 AFK25_08100 fbffe019f9811e55358486ee536085ba 509 Pfam PF13193 AMP-binding enzyme C-terminal domain 417 492 3.5E-18 T 11-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AFK25_08100 fbffe019f9811e55358486ee536085ba 509 ProSitePatterns PS00455 Putative AMP-binding domain signature. 160 171 - T 11-10-2018 IPR020845 AMP-binding, conserved site AFK25_08100 fbffe019f9811e55358486ee536085ba 509 Pfam PF00501 AMP-binding enzyme 8 408 3.7E-114 T 11-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AFK25_08100 fbffe019f9811e55358486ee536085ba 509 SUPERFAMILY SSF56801 3 504 1.96E-159 T 11-10-2018 AFK25_08100 fbffe019f9811e55358486ee536085ba 509 Gene3D G3DSA:3.30.300.310 404 506 2.6E-32 T 11-10-2018 AFK25_08100 fbffe019f9811e55358486ee536085ba 509 Gene3D G3DSA:3.40.50.12780 1 401 9.3E-121 T 11-10-2018 AFK25_03805 9537d6b48dad3f67a04ad1c371655443 73 Pfam PF10960 BhlA holin family 9 66 2.2E-8 T 11-10-2018 IPR024405 Prophage protein BhlA/UviB AFK25_03805 9537d6b48dad3f67a04ad1c371655443 73 ProDom PD019268 UVIB BACTERIOCIN BHLA PLASMID ANTIBIOTIC HOLIN-LIKE PRECURSOR ANTIMICROBIAL SIGNAL PROPHAGE-DERIVED 8 49 2.0E-5 T 11-10-2018 IPR024405 Prophage protein BhlA/UviB AFK25_12500 48ed73dac98c915327a007a4c8918335 114 SMART SM00316 4 75 4.2E-24 T 11-10-2018 IPR022967 RNA-binding domain, S1 AFK25_12500 48ed73dac98c915327a007a4c8918335 114 Gene3D G3DSA:2.40.50.140 2 85 1.3E-27 T 11-10-2018 AFK25_12500 48ed73dac98c915327a007a4c8918335 114 Pfam PF00575 S1 RNA binding domain 4 75 6.9E-20 T 11-10-2018 IPR003029 S1 domain GO:0003676 AFK25_12500 48ed73dac98c915327a007a4c8918335 114 SUPERFAMILY SSF50249 3 81 2.26E-23 T 11-10-2018 IPR012340 Nucleic acid-binding, OB-fold AFK25_08265 e865d2a3e7eaae6a1eea042e27f11ee7 349 SUPERFAMILY SSF52402 8 202 4.12E-52 T 11-10-2018 AFK25_08265 e865d2a3e7eaae6a1eea042e27f11ee7 349 PIRSF PIRSF000089 5 333 9.3E-116 T 11-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 AFK25_08265 e865d2a3e7eaae6a1eea042e27f11ee7 349 SUPERFAMILY SSF52467 209 329 2.49E-48 T 11-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AFK25_08265 e865d2a3e7eaae6a1eea042e27f11ee7 349 Gene3D G3DSA:3.40.50.620 5 206 7.0E-72 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_08265 e865d2a3e7eaae6a1eea042e27f11ee7 349 SMART SM00893 9 198 1.2E-43 T 11-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFK25_08265 e865d2a3e7eaae6a1eea042e27f11ee7 349 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 210 292 3.8E-35 T 11-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 AFK25_08265 e865d2a3e7eaae6a1eea042e27f11ee7 349 Pfam PF01012 Electron transfer flavoprotein domain 10 185 9.1E-42 T 11-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AFK25_08265 e865d2a3e7eaae6a1eea042e27f11ee7 349 Gene3D G3DSA:3.40.50.1220 207 339 6.3E-58 T 11-10-2018 AFK25_04970 8f9632a1f859464a95c1bb4d5cf7e306 151 Pfam PF01243 Pyridoxamine 5'-phosphate oxidase 16 90 2.2E-9 T 11-10-2018 IPR011576 Pyridoxamine 5'-phosphate oxidase, putative KEGG: 00750+1.4.3.5|MetaCyc: PWY-7204|MetaCyc: PWY-7282|Reactome: R-HSA-964975 AFK25_04970 8f9632a1f859464a95c1bb4d5cf7e306 151 Gene3D G3DSA:2.30.110.10 1 150 1.4E-62 T 11-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AFK25_04970 8f9632a1f859464a95c1bb4d5cf7e306 151 SUPERFAMILY SSF50475 9 90 2.81E-10 T 11-10-2018 AFK25_12150 c579f1191b84dbcc030431c3a07ec856 80 Gene3D G3DSA:2.40.240.20 1 77 1.9E-32 T 11-10-2018 AFK25_12150 c579f1191b84dbcc030431c3a07ec856 80 SUPERFAMILY SSF88697 1 80 1.29E-30 T 11-10-2018 IPR015947 PUA-like superfamily AFK25_12150 c579f1191b84dbcc030431c3a07ec856 80 Pfam PF10763 Protein of unknown function (DUF2584) 1 80 4.5E-38 T 11-10-2018 IPR019699 Protein of unknown function DUF2584 AFK25_10905 9b2c6deea248d67a408cb97eba0b11f6 154 SUPERFAMILY SSF55021 77 150 2.37E-11 T 11-10-2018 AFK25_10905 9b2c6deea248d67a408cb97eba0b11f6 154 PIRSF PIRSF025624 5 153 1.0E-59 T 11-10-2018 IPR008310 UPF0735 ACT domain-containing protein AFK25_10905 9b2c6deea248d67a408cb97eba0b11f6 154 Gene3D G3DSA:3.30.70.260 76 151 2.8E-7 T 11-10-2018 AFK25_10905 9b2c6deea248d67a408cb97eba0b11f6 154 Hamap MF_00707 UPF0735 ACT domain-containing protein . 9 153 32.204 T 11-10-2018 IPR008310 UPF0735 ACT domain-containing protein AFK25_10905 9b2c6deea248d67a408cb97eba0b11f6 154 Pfam PF01842 ACT domain 77 142 9.8E-9 T 11-10-2018 IPR002912 ACT domain AFK25_09590 c7313757e9fa17b83455648da32733f1 164 Gene3D G3DSA:3.40.30.10 20 164 3.8E-36 T 11-10-2018 AFK25_09590 c7313757e9fa17b83455648da32733f1 164 SUPERFAMILY SSF52833 3 163 2.16E-34 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_09590 c7313757e9fa17b83455648da32733f1 164 ProSitePatterns PS00194 Thioredoxin family active site. 59 77 - T 11-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFK25_09590 c7313757e9fa17b83455648da32733f1 164 Pfam PF00578 AhpC/TSA family 31 145 3.6E-24 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFK25_12795 c03888ac0672c63113940486d736a984 119 SUPERFAMILY SSF52833 1 116 4.39E-38 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_12795 c03888ac0672c63113940486d736a984 119 TIGRFAM TIGR01617 arsC_related: transcriptional regulator, Spx/MgsR family 3 115 1.0E-33 T 11-10-2018 IPR006504 Transcriptional regulator Spx/MgsR AFK25_12795 c03888ac0672c63113940486d736a984 119 Pfam PF03960 ArsC family 5 114 1.1E-15 T 11-10-2018 IPR006660 Arsenate reductase-like AFK25_12795 c03888ac0672c63113940486d736a984 119 Gene3D G3DSA:3.40.30.10 1 115 1.5E-48 T 11-10-2018 AFK25_07755 ad36a2752bc7bf1c713d30a3c0f15ada 132 Pfam PF13581 Histidine kinase-like ATPase domain 12 118 2.2E-17 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_07755 ad36a2752bc7bf1c713d30a3c0f15ada 132 SUPERFAMILY SSF55874 30 123 1.83E-12 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_07755 ad36a2752bc7bf1c713d30a3c0f15ada 132 Gene3D G3DSA:3.30.565.10 5 129 6.5E-18 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_02275 615dc350875e53060921d86bc22f33b9 173 Gene3D G3DSA:1.10.260.40 9 70 1.7E-6 T 11-10-2018 AFK25_02275 615dc350875e53060921d86bc22f33b9 173 SUPERFAMILY SSF47413 8 62 7.17E-8 T 11-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AFK25_04705 a36ca5e5d4868fa7f77ce2c859189d0d 212 SUPERFAMILY SSF51445 2 210 3.37E-51 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily AFK25_04705 a36ca5e5d4868fa7f77ce2c859189d0d 212 Pfam PF08924 Domain of unknown function (DUF1906) 27 128 7.7E-16 T 11-10-2018 IPR015020 Protein of unknown function DUF1906 AFK25_04705 a36ca5e5d4868fa7f77ce2c859189d0d 212 Gene3D G3DSA:3.20.20.80 1 212 1.3E-71 T 11-10-2018 AFK25_05465 78eeaeeccd4cbf090da646d13149e9f4 26 Pfam PF08183 Stage V sporulation protein family 2 25 6.4E-17 T 11-10-2018 IPR012609 Sporulation stage V, protein M AFK25_07225 ca34cf1d0e5e05a0329a9f1274d5cf0b 128 Pfam PF07238 PilZ domain 10 112 2.7E-9 T 11-10-2018 IPR009875 PilZ domain GO:0035438 AFK25_03655 a671a5d1edfbd82c405c6f8f18eb3370 160 TIGRFAM TIGR02838 spore_V_AC: stage V sporulation protein AC 14 152 4.8E-63 T 11-10-2018 IPR014203 Sporulation stage V, protein AC AFK25_03655 a671a5d1edfbd82c405c6f8f18eb3370 160 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 32 149 4.9E-39 T 11-10-2018 IPR005562 SpoVA AFK25_13775 8bf17515945935a9d988b8acfe8c3c60 500 TIGRFAM TIGR01770 NDH_I_N: proton-translocating NADH-quinone oxidoreductase, chain N 13 485 8.3E-121 T 11-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 AFK25_13775 8bf17515945935a9d988b8acfe8c3c60 500 Hamap MF_00445 NAD(P)H-quinone oxidoreductase subunit 2, chloroplastic [ndhB]. 9 486 17.398 T 11-10-2018 IPR010096 NAD(P)H-quinone oxidoreductase, subunit N/subunit 2 GO:0008137|GO:0042773|GO:0055114 AFK25_13775 8bf17515945935a9d988b8acfe8c3c60 500 Pfam PF00361 Proton-conducting membrane transporter 130 435 3.7E-67 T 11-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13315 48463872cbf2a45bb91b80b184a4e604 350 ProSitePatterns PS01348 MraY family signature 2. 144 155 - T 11-10-2018 IPR018480 Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471 AFK25_13315 48463872cbf2a45bb91b80b184a4e604 350 Pfam PF00953 Glycosyl transferase family 4 71 226 2.4E-41 T 11-10-2018 IPR000715 Glycosyl transferase, family 4 GO:0008963|GO:0016021 KEGG: 00550+2.7.8.13|MetaCyc: PWY-5265|MetaCyc: PWY-6470|MetaCyc: PWY-6471|Reactome: R-HSA-446193|Reactome: R-HSA-4549356 AFK25_03665 b8c720788997aa84b96b1c8860984b67 118 TIGRFAM TIGR02839 spore_V_AE: stage V sporulation protein AE 5 118 1.4E-51 T 11-10-2018 IPR014204 Sporulation stage V, protein AE AFK25_03665 b8c720788997aa84b96b1c8860984b67 118 Pfam PF03862 SpoVAC/SpoVAEB sporulation membrane protein 5 112 1.8E-40 T 11-10-2018 IPR005562 SpoVA AFK25_06840 99f5db9c660736c14f9a6d1571d29736 202 Pfam PF03458 UPF0126 domain 5 78 1.3E-19 T 11-10-2018 IPR005115 Uncharacterised domain UPF0126 AFK25_06840 99f5db9c660736c14f9a6d1571d29736 202 Pfam PF03458 UPF0126 domain 92 161 6.1E-19 T 11-10-2018 IPR005115 Uncharacterised domain UPF0126 AFK25_03920 37366d089095bfb0b327f3fb8534d463 388 ProSitePatterns PS01007 Transposases, Mutator family, signature. 220 244 - T 11-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 AFK25_03920 37366d089095bfb0b327f3fb8534d463 388 Pfam PF00872 Transposase, Mutator family 8 365 1.4E-97 T 11-10-2018 IPR001207 Transposase, mutator type GO:0003677|GO:0004803|GO:0006313 AFK25_06060 c2e237a37671a95b102072442c92d277 496 Hamap MF_00212 Probable malate:quinone oxidoreductase [mqo]. 1 487 53.327 T 11-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 AFK25_06060 c2e237a37671a95b102072442c92d277 496 Gene3D G3DSA:3.30.9.10 108 173 1.3E-8 T 11-10-2018 AFK25_06060 c2e237a37671a95b102072442c92d277 496 Pfam PF06039 Malate:quinone oxidoreductase (Mqo) 2 487 2.1E-242 T 11-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 AFK25_06060 c2e237a37671a95b102072442c92d277 496 TIGRFAM TIGR01320 mal_quin_oxido: malate dehydrogenase (acceptor) 3 485 4.8E-222 T 11-10-2018 IPR006231 Malate:quinone-oxidoreductase GO:0006099|GO:0008924 KEGG: 00020+1.1.5.4|KEGG: 00620+1.1.5.4|MetaCyc: PWY-7254 AFK25_06060 c2e237a37671a95b102072442c92d277 496 SUPERFAMILY SSF51905 1 327 1.48E-25 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_06060 c2e237a37671a95b102072442c92d277 496 Gene3D G3DSA:3.50.50.60 5 252 1.3E-8 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_13620 b3d47e0fecc9bc7396a11f176086a26a 139 Pfam PF04892 VanZ like family 10 133 9.1E-18 T 11-10-2018 IPR006976 VanZ-like AFK25_06540 a9f48690d3d6504d425d3dbeeac2fa8d 107 SUPERFAMILY SSF103481 7 106 1.31E-11 T 11-10-2018 AFK25_06540 a9f48690d3d6504d425d3dbeeac2fa8d 107 Pfam PF02694 Uncharacterised BCR, YnfA/UPF0060 family 3 106 1.3E-43 T 11-10-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 AFK25_06540 a9f48690d3d6504d425d3dbeeac2fa8d 107 Hamap MF_00010 UPF0060 membrane protein YnfA [ynfA]. 1 106 21.831 T 11-10-2018 IPR003844 Uncharacterised protein family UPF0060 GO:0016020 AFK25_12830 1f94a00870721bb6113d56ee8e25e97b 103 SUPERFAMILY SSF54909 1 100 6.6E-28 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel AFK25_12830 1f94a00870721bb6113d56ee8e25e97b 103 Gene3D G3DSA:3.30.70.100 1 103 5.4E-36 T 11-10-2018 AFK25_12830 1f94a00870721bb6113d56ee8e25e97b 103 Pfam PF03992 Antibiotic biosynthesis monooxygenase 1 77 2.4E-20 T 11-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain AFK25_01655 fda1b4105a88f7c6f20e623a36bcb839 493 Gene3D G3DSA:1.10.287.950 189 493 1.5E-46 T 11-10-2018 AFK25_01655 fda1b4105a88f7c6f20e623a36bcb839 493 SUPERFAMILY SSF58104 234 483 2.49E-45 T 11-10-2018 AFK25_01655 fda1b4105a88f7c6f20e623a36bcb839 493 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 293 443 2.7E-28 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_01655 fda1b4105a88f7c6f20e623a36bcb839 493 SMART SM00283 221 482 8.4E-20 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_09605 2c7eadd7c2ae137f644aeeb04af9c9ce 231 Gene3D G3DSA:3.40.50.300 1 229 1.9E-62 T 11-10-2018 AFK25_09605 2c7eadd7c2ae137f644aeeb04af9c9ce 231 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_09605 2c7eadd7c2ae137f644aeeb04af9c9ce 231 SMART SM00382 26 207 1.6E-11 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_09605 2c7eadd7c2ae137f644aeeb04af9c9ce 231 Pfam PF00005 ABC transporter 17 158 3.1E-30 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_09605 2c7eadd7c2ae137f644aeeb04af9c9ce 231 SUPERFAMILY SSF52540 3 209 1.84E-56 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_09605 2c7eadd7c2ae137f644aeeb04af9c9ce 231 TIGRFAM TIGR01189 ccmA: heme ABC exporter, ATP-binding protein CcmA 5 191 2.6E-44 T 11-10-2018 IPR005895 ABC transporter, haem export, CcmA GO:0005215|GO:0017004 AFK25_07450 ebcf7f2055ab4ada94f049030adb0973 109 SUPERFAMILY SSF46785 2 100 9.25E-27 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_07450 ebcf7f2055ab4ada94f049030adb0973 109 Gene3D G3DSA:1.10.10.10 2 91 4.1E-28 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_07450 ebcf7f2055ab4ada94f049030adb0973 109 SMART SM00418 8 84 5.4E-24 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_07450 ebcf7f2055ab4ada94f049030adb0973 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 57 72 7.6E-20 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_07450 ebcf7f2055ab4ada94f049030adb0973 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 42 57 7.6E-20 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_07450 ebcf7f2055ab4ada94f049030adb0973 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 10 25 7.6E-20 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_07450 ebcf7f2055ab4ada94f049030adb0973 109 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 29 40 7.6E-20 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_07450 ebcf7f2055ab4ada94f049030adb0973 109 Pfam PF01022 Bacterial regulatory protein, arsR family 15 60 1.5E-19 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_07685 0f20f5c2524ef97cc04d381895c60ac4 166 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 71 160 7.7E-28 T 11-10-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 AFK25_07685 0f20f5c2524ef97cc04d381895c60ac4 166 Gene3D G3DSA:1.20.120.1630 1 162 1.2E-19 T 11-10-2018 AFK25_04405 dc7263b929c80dd4b951f8debcf09e0c 218 Hamap MF_01680 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase [mtnX]. 1 215 49.376 T 11-10-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 AFK25_04405 dc7263b929c80dd4b951f8debcf09e0c 218 Pfam PF12710 haloacid dehalogenase-like hydrolase 5 176 3.1E-22 T 11-10-2018 AFK25_04405 dc7263b929c80dd4b951f8debcf09e0c 218 Gene3D G3DSA:3.40.50.1000 5 208 5.6E-70 T 11-10-2018 IPR023214 HAD superfamily AFK25_04405 dc7263b929c80dd4b951f8debcf09e0c 218 TIGRFAM TIGR03333 salvage_mtnX: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase 4 214 1.1E-109 T 11-10-2018 IPR017718 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase GO:0016791|GO:0071267 KEGG: 00270+3.1.3.87|MetaCyc: PWY-4361 AFK25_04405 dc7263b929c80dd4b951f8debcf09e0c 218 TIGRFAM TIGR01489 DKMTPPase-SF: 2,3-diketo-5-methylthio-1-phosphopentane phosphatase 2 185 3.0E-51 T 11-10-2018 IPR006384 Pyridoxal phosphate phosphatase-related GO:0016791 AFK25_04405 dc7263b929c80dd4b951f8debcf09e0c 218 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 4 178 4.2E-34 T 11-10-2018 AFK25_04405 dc7263b929c80dd4b951f8debcf09e0c 218 Gene3D G3DSA:3.90.1470.20 14 133 5.6E-70 T 11-10-2018 AFK25_04405 dc7263b929c80dd4b951f8debcf09e0c 218 SUPERFAMILY SSF56784 1 213 2.0E-54 T 11-10-2018 IPR036412 HAD-like superfamily AFK25_12650 8206409fb7ccc16c4bf18f009aac2bb4 210 Pfam PF01022 Bacterial regulatory protein, arsR family 7 53 1.9E-7 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_12650 8206409fb7ccc16c4bf18f009aac2bb4 210 SUPERFAMILY SSF46785 7 185 4.04E-35 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_12650 8206409fb7ccc16c4bf18f009aac2bb4 210 Gene3D G3DSA:1.10.10.10 4 92 4.0E-14 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_04570 d2f7c9f627844438379d40027bdb1e27 104 Pfam PF01638 HxlR-like helix-turn-helix 16 103 1.4E-34 T 11-10-2018 IPR002577 Helix-turn-helix, HxlR type AFK25_04570 d2f7c9f627844438379d40027bdb1e27 104 Gene3D G3DSA:1.10.10.10 2 104 2.9E-39 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_04570 d2f7c9f627844438379d40027bdb1e27 104 SUPERFAMILY SSF46785 5 102 1.72E-33 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_01580 5f9df3114ba721adb264a4da2dbc8cb2 232 Gene3D G3DSA:3.40.50.2300 2 132 3.4E-38 T 11-10-2018 AFK25_01580 5f9df3114ba721adb264a4da2dbc8cb2 232 SMART SM00862 153 228 4.1E-28 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFK25_01580 5f9df3114ba721adb264a4da2dbc8cb2 232 SUPERFAMILY SSF52172 10 189 4.23E-41 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_01580 5f9df3114ba721adb264a4da2dbc8cb2 232 Gene3D G3DSA:1.10.10.10 133 232 1.5E-36 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_01580 5f9df3114ba721adb264a4da2dbc8cb2 232 Pfam PF00072 Response regulator receiver domain 11 120 5.9E-30 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_01580 5f9df3114ba721adb264a4da2dbc8cb2 232 SMART SM00448 9 119 4.5E-39 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_01580 5f9df3114ba721adb264a4da2dbc8cb2 232 Pfam PF00486 Transcriptional regulatory protein, C terminal 153 228 2.3E-27 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFK25_03075 133a5419eaafe04ee354a6fd29fd6298 70 ProDom PD027559 GERMINATION SPORE GERPB PROBABLE PB SPORULATION PB-RELATED 1 46 5.0E-12 T 11-10-2018 IPR024255 Spore germination GerPB AFK25_03075 133a5419eaafe04ee354a6fd29fd6298 70 Pfam PF10803 Spore germination GerPB 1 52 1.2E-30 T 11-10-2018 IPR024255 Spore germination GerPB AFK25_13820 7b08f32e14948376c7b148bac070d4c5 170 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 19 161 5.2E-73 T 11-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13820 7b08f32e14948376c7b148bac070d4c5 170 Gene3D G3DSA:3.40.50.12280 3 169 3.0E-78 T 11-10-2018 AFK25_13820 7b08f32e14948376c7b148bac070d4c5 170 SUPERFAMILY SSF56770 18 163 1.83E-66 T 11-10-2018 AFK25_13820 7b08f32e14948376c7b148bac070d4c5 170 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 46 155 5.8E-26 T 11-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13820 7b08f32e14948376c7b148bac070d4c5 170 Hamap MF_01356 NAD(P)H-quinone oxidoreductase subunit K, chloroplastic [ndhK]. 9 160 42.946 T 11-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_08090 4565dbfa861b12790ee8c63eb7f1fa68 211 Pfam PF03006 Haemolysin-III related 7 204 7.7E-38 T 11-10-2018 IPR004254 AdipoR/Haemolysin-III-related GO:0016021 AFK25_08090 4565dbfa861b12790ee8c63eb7f1fa68 211 TIGRFAM TIGR01065 hlyIII: channel protein, hemolysin III family 11 210 9.8E-62 T 11-10-2018 IPR005744 Hly-III GO:0016021|GO:0019835 AFK25_10730 799a8a1e6962f71e94ddcc36027e6fa3 269 Gene3D G3DSA:1.10.357.10 1 194 1.1E-31 T 11-10-2018 AFK25_10730 799a8a1e6962f71e94ddcc36027e6fa3 269 Pfam PF00440 Bacterial regulatory proteins, tetR family 7 52 9.7E-20 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_10730 799a8a1e6962f71e94ddcc36027e6fa3 269 ProSitePatterns PS01081 TetR-type HTH domain signature. 19 50 - T 11-10-2018 IPR023772 DNA-binding HTH domain, TetR-type, conserved site AFK25_10730 799a8a1e6962f71e94ddcc36027e6fa3 269 SUPERFAMILY SSF46689 3 69 3.08E-20 T 11-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AFK25_10730 799a8a1e6962f71e94ddcc36027e6fa3 269 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 7 20 6.5E-11 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_10730 799a8a1e6962f71e94ddcc36027e6fa3 269 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 28 51 6.5E-11 T 11-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AFK25_00950 1642570ec7ababe2ae5a920ed1cb2308 241 PIRSF PIRSF031509 4 241 3.3E-64 T 11-10-2018 IPR016975 Cell wall-active antibiotic response protein GO:0016021 AFK25_00950 1642570ec7ababe2ae5a920ed1cb2308 241 Pfam PF09922 Cell wall-active antibiotics response 4TMS YvqF 126 238 2.1E-40 T 11-10-2018 IPR024425 Cell wall-active antibiotics response 4TMS YvqF AFK25_13790 13c1c5e3e78bc6b4f005d41ebf9ff4e8 103 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 8 98 3.8E-26 T 11-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like AFK25_13790 13c1c5e3e78bc6b4f005d41ebf9ff4e8 103 Hamap MF_01456 NAD(P)H-quinone oxidoreductase subunit 4L, chloroplastic [ndhE]. 3 103 20.504 T 11-10-2018 IPR001133 NADH-ubiquinone oxidoreductase chain 4L/K GO:0016651|GO:0042773|GO:0055114 AFK25_01705 37f8df5c331031f8de4a90130f22f4b3 92 Gene3D G3DSA:3.30.70.100 1 92 8.8E-28 T 11-10-2018 AFK25_01705 37f8df5c331031f8de4a90130f22f4b3 92 Pfam PF00708 Acylphosphatase 6 90 2.7E-24 T 11-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AFK25_01705 37f8df5c331031f8de4a90130f22f4b3 92 SUPERFAMILY SSF54975 2 91 1.85E-25 T 11-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AFK25_09200 8aee55d0d2deb26c3bdb14351042ffcc 485 Gene3D G3DSA:3.40.50.300 1 253 5.0E-72 T 11-10-2018 AFK25_09200 8aee55d0d2deb26c3bdb14351042ffcc 485 SUPERFAMILY SSF52540 3 227 6.37E-63 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_09200 8aee55d0d2deb26c3bdb14351042ffcc 485 ProSitePatterns PS00211 ABC transporters family signature. 141 155 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_09200 8aee55d0d2deb26c3bdb14351042ffcc 485 SMART SM00382 28 213 8.4E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_09200 8aee55d0d2deb26c3bdb14351042ffcc 485 Pfam PF01955 Adenosylcobinamide amidohydrolase 280 469 1.7E-54 T 11-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ AFK25_09200 8aee55d0d2deb26c3bdb14351042ffcc 485 Pfam PF00005 ABC transporter 19 169 1.6E-32 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_03225 0b98f660ddacdd29e74222ced3c9879a 89 TIGRFAM TIGR01165 cbiN: cobalt transport protein 5 84 3.9E-32 T 11-10-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 AFK25_03225 0b98f660ddacdd29e74222ced3c9879a 89 Hamap MF_00330 Cobalt transport protein CbiN [cbiN]. 1 89 42.272 T 11-10-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 AFK25_03225 0b98f660ddacdd29e74222ced3c9879a 89 Pfam PF02553 Cobalt transport protein component CbiN 4 69 2.5E-28 T 11-10-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 AFK25_12635 2232b2aba571ba3c30a0ba573ba8b660 312 SUPERFAMILY SSF56112 16 286 2.86E-11 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily AFK25_12635 2232b2aba571ba3c30a0ba573ba8b660 312 TIGRFAM TIGR02905 spore_yutH: spore coat protein YutH 3 298 1.9E-98 T 11-10-2018 IPR014254 Spore coat protein YutH AFK25_12635 2232b2aba571ba3c30a0ba573ba8b660 312 Gene3D G3DSA:3.90.1200.10 78 298 3.8E-25 T 11-10-2018 AFK25_05400 bc796df4846ee5845f1d4ade9e1eb43e 204 SUPERFAMILY SSF52540 3 192 1.46E-69 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_05400 bc796df4846ee5845f1d4ade9e1eb43e 204 ProSitePatterns PS00856 Guanylate kinase-like signature. 40 57 - T 11-10-2018 IPR020590 Guanylate kinase, conserved site KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221 AFK25_05400 bc796df4846ee5845f1d4ade9e1eb43e 204 TIGRFAM TIGR03263 guanyl_kin: guanylate kinase 5 184 3.0E-74 T 11-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 AFK25_05400 bc796df4846ee5845f1d4ade9e1eb43e 204 Gene3D G3DSA:3.40.50.300 9 183 1.8E-69 T 11-10-2018 AFK25_05400 bc796df4846ee5845f1d4ade9e1eb43e 204 Gene3D G3DSA:3.30.63.10 37 96 1.8E-69 T 11-10-2018 AFK25_05400 bc796df4846ee5845f1d4ade9e1eb43e 204 SMART SM00072 4 187 7.1E-82 T 11-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit AFK25_05400 bc796df4846ee5845f1d4ade9e1eb43e 204 Pfam PF00625 Guanylate kinase 7 185 1.9E-53 T 11-10-2018 IPR008145 Guanylate kinase/L-type calcium channel beta subunit AFK25_05400 bc796df4846ee5845f1d4ade9e1eb43e 204 Hamap MF_00328 Guanylate kinase [gmk]. 3 187 37.745 T 11-10-2018 IPR017665 Guanylate kinase GO:0004385|GO:0006163 KEGG: 00230+2.7.4.8|MetaCyc: PWY-7221|Reactome: R-HSA-2161541|Reactome: R-HSA-499943 AFK25_08340 1c6c5bb1fe8dcfc4e9b52a71aa111f5c 453 SUPERFAMILY SSF103190 369 452 1.99E-11 T 11-10-2018 IPR029151 Periplasmic sensor-like domain superfamily AFK25_08340 1c6c5bb1fe8dcfc4e9b52a71aa111f5c 453 Gene3D G3DSA:3.30.450.20 358 451 5.0E-16 T 11-10-2018 AFK25_08340 1c6c5bb1fe8dcfc4e9b52a71aa111f5c 453 Gene3D G3DSA:1.10.287.950 9 326 5.0E-45 T 11-10-2018 AFK25_08340 1c6c5bb1fe8dcfc4e9b52a71aa111f5c 453 SMART SM00283 48 327 1.2E-17 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_08340 1c6c5bb1fe8dcfc4e9b52a71aa111f5c 453 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 179 208 2.8E-13 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_08340 1c6c5bb1fe8dcfc4e9b52a71aa111f5c 453 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 150 177 2.8E-13 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_08340 1c6c5bb1fe8dcfc4e9b52a71aa111f5c 453 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 69 98 2.8E-13 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_08340 1c6c5bb1fe8dcfc4e9b52a71aa111f5c 453 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 130 277 4.0E-31 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_08340 1c6c5bb1fe8dcfc4e9b52a71aa111f5c 453 SUPERFAMILY SSF58104 20 324 4.45E-44 T 11-10-2018 AFK25_00115 96cdacfa7aad28ef04c761681252f6cc 162 Hamap MF_00972 tRNA-specific adenosine deaminase [tadA]. 8 149 48.165 T 11-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 AFK25_00115 96cdacfa7aad28ef04c761681252f6cc 162 Pfam PF14437 MafB19-like deaminase 3 149 1.4E-41 T 11-10-2018 IPR028883 tRNA-specific adenosine deaminase GO:0002100|GO:0008251 Reactome: R-HSA-6782315 AFK25_00115 96cdacfa7aad28ef04c761681252f6cc 162 Gene3D G3DSA:3.40.140.10 1 162 2.2E-63 T 11-10-2018 AFK25_00115 96cdacfa7aad28ef04c761681252f6cc 162 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 53 90 - T 11-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 AFK25_00115 96cdacfa7aad28ef04c761681252f6cc 162 SUPERFAMILY SSF53927 3 153 2.17E-55 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFK25_12965 5e355ff21219af7672a624ebe1787714 152 SUPERFAMILY SSF55811 3 128 3.11E-31 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFK25_12965 5e355ff21219af7672a624ebe1787714 152 Pfam PF00293 NUDIX domain 6 123 3.0E-19 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFK25_12965 5e355ff21219af7672a624ebe1787714 152 PRINTS PR00502 NUDIX hydrolase family signature 26 40 2.3E-6 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFK25_12965 5e355ff21219af7672a624ebe1787714 152 PRINTS PR00502 NUDIX hydrolase family signature 40 55 2.3E-6 T 11-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AFK25_12965 5e355ff21219af7672a624ebe1787714 152 Gene3D G3DSA:3.90.79.10 1 152 2.2E-45 T 11-10-2018 AFK25_05075 e50d86ca9e056ef919eb727785aa907f 138 Pfam PF00571 CBS domain 68 118 3.9E-14 T 11-10-2018 IPR000644 CBS domain AFK25_05075 e50d86ca9e056ef919eb727785aa907f 138 Pfam PF00571 CBS domain 4 54 8.3E-13 T 11-10-2018 IPR000644 CBS domain AFK25_05075 e50d86ca9e056ef919eb727785aa907f 138 Gene3D G3DSA:3.10.580.10 1 123 7.8E-39 T 11-10-2018 AFK25_05075 e50d86ca9e056ef919eb727785aa907f 138 SUPERFAMILY SSF54631 2 117 3.28E-34 T 11-10-2018 AFK25_05075 e50d86ca9e056ef919eb727785aa907f 138 SMART SM00116 11 58 7.5E-10 T 11-10-2018 IPR000644 CBS domain AFK25_05075 e50d86ca9e056ef919eb727785aa907f 138 SMART SM00116 75 122 9.3E-13 T 11-10-2018 IPR000644 CBS domain AFK25_03720 51f2a0a696a7da793d3efa58cab4a02e 225 Pfam PF04239 Protein of unknown function (DUF421) 89 204 2.9E-31 T 11-10-2018 IPR007353 Protein of unknown function DUF421 AFK25_03720 51f2a0a696a7da793d3efa58cab4a02e 225 Gene3D G3DSA:3.30.240.20 168 225 2.3E-16 T 11-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily AFK25_03720 51f2a0a696a7da793d3efa58cab4a02e 225 Gene3D G3DSA:3.30.240.20 80 155 1.7E-24 T 11-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily AFK25_02600 27654625c5c7527083afc51fced5dd66 129 ProDom PD081567 YHCU 1 109 2.0E-21 T 11-10-2018 IPR020355 Uncharacterised protein family YhcU AFK25_02600 27654625c5c7527083afc51fced5dd66 129 Pfam PF17326 Family of unknown function (DUF5365) 1 113 6.6E-39 T 11-10-2018 IPR020355 Uncharacterised protein family YhcU AFK25_08550 d55cf7e68be82f59ca062d7899ab3251 137 Pfam PF13476 AAA domain 8 118 2.7E-8 T 11-10-2018 IPR038729 Rad50/SbcC-type AAA domain AFK25_08550 d55cf7e68be82f59ca062d7899ab3251 137 SUPERFAMILY SSF52540 4 117 2.04E-9 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_08550 d55cf7e68be82f59ca062d7899ab3251 137 Gene3D G3DSA:3.40.50.300 4 135 2.0E-17 T 11-10-2018 AFK25_06420 44a6f917a9503e4bf865ea26f477974e 132 Pfam PF07681 DoxX 6 92 9.3E-22 T 11-10-2018 IPR032808 DoxX family AFK25_04725 b29796e92ca45d593cc108542b286f4f 461 Pfam PF13641 Glycosyltransferase like family 2 54 319 1.0E-22 T 11-10-2018 AFK25_04725 b29796e92ca45d593cc108542b286f4f 461 SUPERFAMILY SSF53448 47 366 1.22E-48 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_04725 b29796e92ca45d593cc108542b286f4f 461 Gene3D G3DSA:3.90.550.10 43 315 1.0E-41 T 11-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AFK25_08405 754ed14e37aeb74507f435b3e1883147 67 Pfam PF09851 Short C-terminal domain 41 62 4.2E-7 T 11-10-2018 IPR018649 SHOCT domain AFK25_04080 811fb53ff04a864213579c03b3f6ca76 358 Gene3D G3DSA:1.20.1090.10 158 358 6.3E-64 T 11-10-2018 AFK25_04080 811fb53ff04a864213579c03b3f6ca76 358 Gene3D G3DSA:3.40.50.1970 7 156 3.1E-32 T 11-10-2018 AFK25_04080 811fb53ff04a864213579c03b3f6ca76 358 Pfam PF00465 Iron-containing alcohol dehydrogenase 10 342 2.7E-55 T 11-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 AFK25_04080 811fb53ff04a864213579c03b3f6ca76 358 PIRSF PIRSF000112 1 358 3.6E-117 T 11-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 AFK25_04080 811fb53ff04a864213579c03b3f6ca76 358 SUPERFAMILY SSF56796 10 353 8.5E-69 T 11-10-2018 AFK25_05330 c6f129094ab994cbd7962803af403155 178 Hamap MF_01219 Bifunctional protein PyrR [pyrR]. 3 178 39.077 T 11-10-2018 IPR023050 Bifunctional protein PyrR KEGG: 00240+2.4.2.9|MetaCyc: PWY-7183 AFK25_05330 c6f129094ab994cbd7962803af403155 178 Pfam PF00156 Phosphoribosyl transferase domain 6 150 1.3E-20 T 11-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AFK25_05330 c6f129094ab994cbd7962803af403155 178 Gene3D G3DSA:3.40.50.2020 1 178 8.7E-61 T 11-10-2018 AFK25_05330 c6f129094ab994cbd7962803af403155 178 SUPERFAMILY SSF53271 5 174 1.06E-43 T 11-10-2018 IPR029057 Phosphoribosyltransferase-like AFK25_04920 d005e1d94fdced2ca11b044d538e4885 216 SUPERFAMILY SSF52540 3 208 1.21E-54 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_04920 d005e1d94fdced2ca11b044d538e4885 216 ProSitePatterns PS00211 ABC transporters family signature. 131 145 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_04920 d005e1d94fdced2ca11b044d538e4885 216 Gene3D G3DSA:3.40.50.300 1 213 3.6E-54 T 11-10-2018 AFK25_04920 d005e1d94fdced2ca11b044d538e4885 216 SMART SM00382 28 210 2.1E-14 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_04920 d005e1d94fdced2ca11b044d538e4885 216 Pfam PF00005 ABC transporter 20 159 7.4E-31 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_12695 ad12cdc8d79953c50f17c57bbe49f897 248 Pfam PF09560 Sporulation protein YunB (Spo_YunB) 143 232 1.7E-31 T 11-10-2018 IPR014197 Sporulation protein YunB AFK25_12695 ad12cdc8d79953c50f17c57bbe49f897 248 PIRSF PIRSF021383 3 248 1.3E-85 T 11-10-2018 IPR014197 Sporulation protein YunB AFK25_12695 ad12cdc8d79953c50f17c57bbe49f897 248 TIGRFAM TIGR02832 spo_yunB: sporulation protein YunB 13 235 6.6E-66 T 11-10-2018 IPR014197 Sporulation protein YunB AFK25_03015 e8876eaafd346612ac5eb63f15a5c3a8 428 ProSitePatterns PS00161 Isocitrate lyase signature. 186 191 - T 11-10-2018 IPR018523 Isocitrate lyase/phosphorylmutase, conserved site GO:0003824 AFK25_03015 e8876eaafd346612ac5eb63f15a5c3a8 428 SUPERFAMILY SSF51621 6 425 2.24E-159 T 11-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AFK25_03015 e8876eaafd346612ac5eb63f15a5c3a8 428 TIGRFAM TIGR01346 isocit_lyase: isocitrate lyase 9 250 3.7E-109 T 11-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 AFK25_03015 e8876eaafd346612ac5eb63f15a5c3a8 428 PIRSF PIRSF001362 1 428 8.8E-243 T 11-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 AFK25_03015 e8876eaafd346612ac5eb63f15a5c3a8 428 Gene3D G3DSA:3.20.20.60 4 408 2.0E-176 T 11-10-2018 AFK25_03015 e8876eaafd346612ac5eb63f15a5c3a8 428 Pfam PF00463 Isocitrate lyase family 250 425 7.7E-47 T 11-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 AFK25_03015 e8876eaafd346612ac5eb63f15a5c3a8 428 Pfam PF00463 Isocitrate lyase family 13 249 4.3E-62 T 11-10-2018 IPR006254 Isocitrate lyase GO:0004451|GO:0019752 KEGG: 00630+4.1.3.1|MetaCyc: PWY-6969 AFK25_02735 cd491d6b580c330fa70b2db57b0ae06d 260 Gene3D G3DSA:3.40.190.10 121 218 3.5E-78 T 11-10-2018 AFK25_02735 cd491d6b580c330fa70b2db57b0ae06d 260 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 61 74 - T 11-10-2018 IPR018313 Solute-binding protein family 3, conserved site AFK25_02735 cd491d6b580c330fa70b2db57b0ae06d 260 SMART SM00062 38 257 4.3E-82 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFK25_02735 cd491d6b580c330fa70b2db57b0ae06d 260 SMART SM00079 38 256 0.0021 T 11-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 AFK25_02735 cd491d6b580c330fa70b2db57b0ae06d 260 Gene3D G3DSA:3.40.190.10 37 249 3.5E-78 T 11-10-2018 AFK25_02735 cd491d6b580c330fa70b2db57b0ae06d 260 SUPERFAMILY SSF53850 1 257 3.82E-76 T 11-10-2018 AFK25_02735 cd491d6b580c330fa70b2db57b0ae06d 260 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 39 256 1.5E-69 T 11-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AFK25_09725 c0748fadef9145be204686b70a76d0c5 312 Pfam PF11728 Putative aromatic acid exporter C-terminal domain 146 310 1.1E-58 T 11-10-2018 IPR021062 Putative aromatic acid exporter, C-terminal AFK25_09725 c0748fadef9145be204686b70a76d0c5 312 Gene3D G3DSA:1.20.120.940 140 312 1.5E-54 T 11-10-2018 IPR038323 Putative aromatic acid exporter, C-terminal domain superfamily AFK25_09725 c0748fadef9145be204686b70a76d0c5 312 Pfam PF06081 Aromatic acid exporter family member 1 3 142 8.4E-49 T 11-10-2018 IPR010343 Aromatic acid exporter family member 1 AFK25_07490 275a89e74ae87899c608b6ce67bef80a 263 Gene3D G3DSA:3.40.50.1110 27 260 7.7E-36 T 11-10-2018 IPR036514 SGNH hydrolase superfamily AFK25_07490 275a89e74ae87899c608b6ce67bef80a 263 SUPERFAMILY SSF52266 53 256 3.38E-37 T 11-10-2018 AFK25_07490 275a89e74ae87899c608b6ce67bef80a 263 Pfam PF13472 GDSL-like Lipase/Acylhydrolase family 59 247 4.7E-25 T 11-10-2018 IPR013830 SGNH hydrolase-type esterase domain AFK25_11085 e1aa09bde9577492474c3735124f0cc5 304 SUPERFAMILY SSF56112 21 269 2.21E-9 T 11-10-2018 IPR011009 Protein kinase-like domain superfamily AFK25_11085 e1aa09bde9577492474c3735124f0cc5 304 Gene3D G3DSA:3.90.1200.10 69 290 2.6E-10 T 11-10-2018 AFK25_11740 a29901031fabf9638fc1251f7ded0531 168 Gene3D G3DSA:3.40.30.10 1 167 2.0E-48 T 11-10-2018 AFK25_11740 a29901031fabf9638fc1251f7ded0531 168 ProSitePatterns PS01265 Tpx family signature. 83 94 - T 11-10-2018 IPR018219 Thiol peroxidase conserved site GO:0016684|GO:0055114 KEGG: 00480+1.11.1.15 AFK25_11740 a29901031fabf9638fc1251f7ded0531 168 SUPERFAMILY SSF52833 1 160 2.24E-44 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_11740 a29901031fabf9638fc1251f7ded0531 168 Hamap MF_00269 Thiol peroxidase [tpx]. 3 163 38.882 T 11-10-2018 IPR002065 Thiol peroxidase Tpx GO:0008379|GO:0016209|GO:0055114 KEGG: 00480+1.11.1.15 AFK25_11740 a29901031fabf9638fc1251f7ded0531 168 Pfam PF08534 Redoxin 19 159 2.3E-22 T 11-10-2018 IPR013740 Redoxin GO:0016491 Reactome: R-HSA-3299685|Reactome: R-HSA-5628897 AFK25_00455 5809237ae6873f194eae3064968c955e 180 PIRSF PIRSF015034 1 179 1.8E-65 T 11-10-2018 IPR025542 YacH protein AFK25_00455 5809237ae6873f194eae3064968c955e 180 SUPERFAMILY SSF46600 139 173 6.93E-6 T 11-10-2018 IPR036876 UVR domain superfamily AFK25_00455 5809237ae6873f194eae3064968c955e 180 Pfam PF02151 UvrB/uvrC motif 139 172 7.2E-9 T 11-10-2018 IPR001943 UVR domain GO:0005515 AFK25_06500 1349cd205de04204ab818cc102741343 569 Pfam PF00512 His Kinase A (phospho-acceptor) domain 359 421 1.2E-12 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_06500 1349cd205de04204ab818cc102741343 569 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 237 349 5.0E-9 T 11-10-2018 IPR000014 PAS domain AFK25_06500 1349cd205de04204ab818cc102741343 569 SUPERFAMILY SSF55785 239 343 1.76E-6 T 11-10-2018 IPR035965 PAS domain superfamily AFK25_06500 1349cd205de04204ab818cc102741343 569 SMART SM00387 464 569 1.8E-31 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_06500 1349cd205de04204ab818cc102741343 569 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 465 567 6.3E-20 T 11-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AFK25_06500 1349cd205de04204ab818cc102741343 569 SUPERFAMILY SSF55874 414 567 1.11E-37 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_06500 1349cd205de04204ab818cc102741343 569 Gene3D G3DSA:3.30.565.10 419 567 1.1E-40 T 11-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AFK25_06500 1349cd205de04204ab818cc102741343 569 SMART SM00388 358 424 6.3E-14 T 11-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AFK25_06500 1349cd205de04204ab818cc102741343 569 Gene3D G3DSA:3.30.450.20 224 341 6.6E-10 T 11-10-2018 AFK25_06500 1349cd205de04204ab818cc102741343 569 SUPERFAMILY SSF47384 352 422 2.35E-12 T 11-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AFK25_06500 1349cd205de04204ab818cc102741343 569 Gene3D G3DSA:1.10.287.130 342 418 2.0E-17 T 11-10-2018 AFK25_06500 1349cd205de04204ab818cc102741343 569 PRINTS PR00344 Bacterial sensor protein C-terminal signature 529 547 6.0E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_06500 1349cd205de04204ab818cc102741343 569 PRINTS PR00344 Bacterial sensor protein C-terminal signature 518 528 6.0E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_06500 1349cd205de04204ab818cc102741343 569 PRINTS PR00344 Bacterial sensor protein C-terminal signature 553 566 6.0E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_06500 1349cd205de04204ab818cc102741343 569 PRINTS PR00344 Bacterial sensor protein C-terminal signature 500 514 6.0E-17 T 11-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AFK25_07035 41dbc758fb9c3188b3e0244d780e5fa5 557 SUPERFAMILY SSF58104 224 555 1.44E-65 T 11-10-2018 AFK25_07035 41dbc758fb9c3188b3e0244d780e5fa5 557 SMART SM00304 199 252 8.4E-6 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_07035 41dbc758fb9c3188b3e0244d780e5fa5 557 Pfam PF12729 Four helix bundle sensory module for signal transduction 1 169 8.6E-9 T 11-10-2018 IPR024478 Chemotaxis methyl-accepting receptor HlyB-like, 4HB MCP domain AFK25_07035 41dbc758fb9c3188b3e0244d780e5fa5 557 SMART SM00283 281 556 1.3E-64 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_07035 41dbc758fb9c3188b3e0244d780e5fa5 557 Gene3D G3DSA:1.10.287.950 261 556 3.5E-65 T 11-10-2018 AFK25_07035 41dbc758fb9c3188b3e0244d780e5fa5 557 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 379 406 5.0E-22 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_07035 41dbc758fb9c3188b3e0244d780e5fa5 557 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 408 437 5.0E-22 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_07035 41dbc758fb9c3188b3e0244d780e5fa5 557 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 1 23 5.0E-22 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_07035 41dbc758fb9c3188b3e0244d780e5fa5 557 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 345 509 4.9E-42 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_07035 41dbc758fb9c3188b3e0244d780e5fa5 557 Gene3D G3DSA:1.20.1480.50 160 258 9.3E-10 T 11-10-2018 AFK25_06465 6b33f447ddcf10e95e18b39f3cc0b83e 686 Pfam PF14345 GDYXXLXY protein 541 682 8.3E-34 T 11-10-2018 IPR025833 GDYXXLXY protein AFK25_06465 6b33f447ddcf10e95e18b39f3cc0b83e 686 Pfam PF09925 Predicted membrane protein (DUF2157) 8 111 5.5E-15 T 11-10-2018 IPR018677 Domain of unknown function DUF2157 AFK25_10220 3cc66240f83cccc547b8e9b4c1230907 277 Pfam PF00950 ABC 3 transport family 7 270 6.2E-66 T 11-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 AFK25_10220 3cc66240f83cccc547b8e9b4c1230907 277 SUPERFAMILY SSF81345 4 267 4.58E-38 T 11-10-2018 IPR037294 ABC transporter, BtuC-like AFK25_10220 3cc66240f83cccc547b8e9b4c1230907 277 Gene3D G3DSA:1.10.3470.10 61 273 4.6E-11 T 11-10-2018 IPR037294 ABC transporter, BtuC-like AFK25_07985 6e568ad4e54bdfb336f12e23a15e5e6d 447 Pfam PF02386 Cation transport protein 38 436 1.0E-57 T 11-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 AFK25_12715 a4e5ec91d63ede75409e8b7ede862883 282 Gene3D G3DSA:3.20.20.410 1 281 2.4E-101 T 11-10-2018 IPR036520 UPF0759 superfamily AFK25_12715 a4e5ec91d63ede75409e8b7ede862883 282 SUPERFAMILY SSF117396 1 268 7.32E-87 T 11-10-2018 IPR036520 UPF0759 superfamily AFK25_12715 a4e5ec91d63ede75409e8b7ede862883 282 Pfam PF01904 Protein of unknown function DUF72 16 264 4.9E-64 T 11-10-2018 IPR002763 Protein of unknown function DUF72 AFK25_05300 f1dbe873f5a67d78d6660aaa94628168 90 Pfam PF02325 YGGT family 10 76 2.4E-24 T 11-10-2018 IPR003425 CCB3/YggT GO:0016020 AFK25_09255 cd65136f77e72f64daf3e5cb38bd3f83 370 Gene3D G3DSA:3.40.710.10 19 271 2.7E-91 T 11-10-2018 AFK25_09255 cd65136f77e72f64daf3e5cb38bd3f83 370 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 104 121 4.2E-16 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFK25_09255 cd65136f77e72f64daf3e5cb38bd3f83 370 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 56 67 4.2E-16 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFK25_09255 cd65136f77e72f64daf3e5cb38bd3f83 370 PRINTS PR00725 D-Ala-D-Ala carboxypeptidase 1 (S11) family signature 131 144 4.2E-16 T 11-10-2018 IPR018044 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A GO:0006508|GO:0009002 AFK25_09255 cd65136f77e72f64daf3e5cb38bd3f83 370 Pfam PF00768 D-alanyl-D-alanine carboxypeptidase 23 250 1.8E-73 T 11-10-2018 IPR001967 Peptidase S11, D-alanyl-D-alanine carboxypeptidase A, N-terminal GO:0006508|GO:0009002 AFK25_09255 cd65136f77e72f64daf3e5cb38bd3f83 370 Gene3D G3DSA:2.30.140.30 272 357 7.4E-28 T 11-10-2018 AFK25_09255 cd65136f77e72f64daf3e5cb38bd3f83 370 SUPERFAMILY SSF56601 5 268 1.04E-70 T 11-10-2018 IPR012338 Beta-lactamase/transpeptidase-like AFK25_09320 3ee155421dc8b5070455a2fc8806eee5 258 Hamap MF_01805 Segregation and condensation protein A [scpA]. 19 258 26.964 T 11-10-2018 IPR003768 Segregation and condensation protein A AFK25_09320 3ee155421dc8b5070455a2fc8806eee5 258 Pfam PF02616 Segregation and condensation protein ScpA 36 254 5.0E-59 T 11-10-2018 IPR003768 Segregation and condensation protein A AFK25_01040 bdee799f9e988b292d72c21e211df655 221 Pfam PF01522 Polysaccharide deacetylase 30 145 4.1E-28 T 11-10-2018 IPR002509 NodB homology domain GO:0005975|GO:0016810 AFK25_01040 bdee799f9e988b292d72c21e211df655 221 Gene3D G3DSA:3.20.20.370 19 221 7.3E-55 T 11-10-2018 AFK25_01040 bdee799f9e988b292d72c21e211df655 221 SUPERFAMILY SSF88713 28 220 9.34E-55 T 11-10-2018 IPR011330 Glycoside hydrolase/deacetylase, beta/alpha-barrel GO:0003824|GO:0005975 AFK25_04150 19c1e2dcceddae0a2283a6849b9e4ff3 128 SUPERFAMILY SSF50118 4 115 4.14E-28 T 11-10-2018 AFK25_04150 19c1e2dcceddae0a2283a6849b9e4ff3 128 Pfam PF02452 PemK-like, MazF-like toxin of type II toxin-antitoxin system 7 116 1.1E-20 T 11-10-2018 IPR003477 mRNA interferase PemK-like GO:0003677 AFK25_04150 19c1e2dcceddae0a2283a6849b9e4ff3 128 Gene3D G3DSA:2.30.30.110 1 125 1.9E-36 T 11-10-2018 IPR011067 Plasmid maintenance toxin/Cell growth inhibitor AFK25_00525 fbd216cb87fa3d7a24bd4cf4867bd531 49 SUPERFAMILY SSF57829 1 49 1.16E-16 T 11-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AFK25_00525 fbd216cb87fa3d7a24bd4cf4867bd531 49 Hamap MF_00294 50S ribosomal protein L33 [rpmG]. 1 49 18.28 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00525 fbd216cb87fa3d7a24bd4cf4867bd531 49 TIGRFAM TIGR01023 rpmG_bact: ribosomal protein bL33 2 49 1.2E-18 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00525 fbd216cb87fa3d7a24bd4cf4867bd531 49 Pfam PF00471 Ribosomal protein L33 3 49 4.9E-20 T 11-10-2018 IPR001705 Ribosomal protein L33 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_00525 fbd216cb87fa3d7a24bd4cf4867bd531 49 Gene3D G3DSA:2.20.28.120 1 49 1.3E-19 T 11-10-2018 IPR038584 Ribosomal protein L33 superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_03270 c483fd3d98d70cd2946376f4c2b1e1b1 233 PIRSF PIRSF036427 1 233 5.8E-75 T 11-10-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 AFK25_03270 c483fd3d98d70cd2946376f4c2b1e1b1 233 Gene3D G3DSA:3.40.1010.10 1 132 3.5E-38 T 11-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AFK25_03270 c483fd3d98d70cd2946376f4c2b1e1b1 233 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 211 1.8E-50 T 11-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AFK25_03270 c483fd3d98d70cd2946376f4c2b1e1b1 233 Gene3D G3DSA:3.30.950.10 133 233 1.1E-14 T 11-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AFK25_03270 c483fd3d98d70cd2946376f4c2b1e1b1 233 TIGRFAM TIGR01467 cobI_cbiL: precorrin-2 C(20)-methyltransferase 3 233 8.1E-80 T 11-10-2018 IPR006364 Precorrin-2 C(20)-methyltransferase domain GO:0008757|GO:0009236 AFK25_03270 c483fd3d98d70cd2946376f4c2b1e1b1 233 SUPERFAMILY SSF53790 1 232 2.88E-47 T 11-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AFK25_06405 1665af7acb91eb9cb8506efccda27fbf 396 SUPERFAMILY SSF103473 12 392 3.66E-54 T 11-10-2018 IPR036259 MFS transporter superfamily AFK25_06405 1665af7acb91eb9cb8506efccda27fbf 396 Pfam PF07690 Major Facilitator Superfamily 23 359 2.5E-32 T 11-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AFK25_06405 1665af7acb91eb9cb8506efccda27fbf 396 Gene3D G3DSA:1.20.1250.20 3 396 1.7E-46 T 11-10-2018 AFK25_06405 1665af7acb91eb9cb8506efccda27fbf 396 ProSitePatterns PS00216 Sugar transport proteins signature 1. 276 293 - T 11-10-2018 IPR005829 Sugar transporter, conserved site GO:0005215|GO:0016021|GO:0055085 AFK25_13330 3bd7c20050ec17d901ba9eca28f6b82d 249 Pfam PF00395 S-layer homology domain 77 119 1.7E-11 T 11-10-2018 IPR001119 S-layer homology domain AFK25_13330 3bd7c20050ec17d901ba9eca28f6b82d 249 Pfam PF00395 S-layer homology domain 137 179 5.1E-12 T 11-10-2018 IPR001119 S-layer homology domain AFK25_13330 3bd7c20050ec17d901ba9eca28f6b82d 249 Pfam PF00395 S-layer homology domain 198 239 9.4E-4 T 11-10-2018 IPR001119 S-layer homology domain AFK25_11695 754d9e2b57c24ddd1609e0aa86d5a56a 225 SMART SM00849 7 192 4.4E-9 T 11-10-2018 IPR001279 Metallo-beta-lactamase AFK25_11695 754d9e2b57c24ddd1609e0aa86d5a56a 225 SUPERFAMILY SSF56281 1 215 6.68E-38 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_11695 754d9e2b57c24ddd1609e0aa86d5a56a 225 Pfam PF13483 Beta-lactamase superfamily domain 2 192 4.7E-29 T 11-10-2018 AFK25_11695 754d9e2b57c24ddd1609e0aa86d5a56a 225 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 1 225 38.808 T 11-10-2018 IPR022877 Protein of unknown funcion UPF0173 AFK25_11695 754d9e2b57c24ddd1609e0aa86d5a56a 225 Gene3D G3DSA:3.60.15.10 1 225 1.1E-74 T 11-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AFK25_01905 4973a2e3f8b551c4d8d79fe6afad7bf2 325 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 2 169 3.1E-29 T 11-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase AFK25_08070 d285e5dcffbcb8a945c286a352134696 198 Gene3D G3DSA:3.30.70.270 115 198 1.8E-6 T 11-10-2018 AFK25_08070 d285e5dcffbcb8a945c286a352134696 198 SUPERFAMILY SSF55073 118 196 1.73E-7 T 11-10-2018 IPR029787 Nucleotide cyclase AFK25_01355 d22a117fce3a919d5303d8e8c5852d67 340 Pfam PF11258 Protein of unknown function (DUF3048) N-terminal domain 55 195 1.7E-52 T 11-10-2018 IPR021416 Protein of unknown function DUF3048, N-terminal AFK25_01355 d22a117fce3a919d5303d8e8c5852d67 340 Gene3D G3DSA:3.50.90.10 38 340 6.7E-112 T 11-10-2018 IPR023158 YerB-like superfamily AFK25_01355 d22a117fce3a919d5303d8e8c5852d67 340 SUPERFAMILY SSF159774 51 339 1.44E-99 T 11-10-2018 IPR023158 YerB-like superfamily AFK25_01355 d22a117fce3a919d5303d8e8c5852d67 340 Pfam PF17479 Protein of unknown function (DUF3048) C-terminal domain 220 328 8.0E-24 T 11-10-2018 IPR035328 Protein of unknown function DUF3048, C-terminal domain AFK25_12065 0e95392b13563c29eabb4eb0c0625fcd 187 Pfam PF05685 Putative restriction endonuclease 12 179 5.0E-33 T 11-10-2018 IPR008538 Domain of unknown function DUF820 AFK25_12065 0e95392b13563c29eabb4eb0c0625fcd 187 Gene3D G3DSA:3.90.1570.10 5 187 1.8E-41 T 11-10-2018 AFK25_12065 0e95392b13563c29eabb4eb0c0625fcd 187 SUPERFAMILY SSF52980 3 186 2.79E-41 T 11-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AFK25_03165 ccb3bef30436356d470b6419f4b152b8 481 Pfam PF01593 Flavin containing amine oxidoreductase 11 472 4.9E-32 T 11-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AFK25_03165 ccb3bef30436356d470b6419f4b152b8 481 Gene3D G3DSA:3.50.50.60 196 319 3.5E-19 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_03165 ccb3bef30436356d470b6419f4b152b8 481 Gene3D G3DSA:3.50.50.60 1 91 2.7E-23 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_03165 ccb3bef30436356d470b6419f4b152b8 481 TIGRFAM TIGR02734 crtI_fam: phytoene desaturase 4 473 6.2E-99 T 11-10-2018 IPR014105 Carotenoid/retinoid oxidoreductase GO:0016117|GO:0055114 AFK25_03165 ccb3bef30436356d470b6419f4b152b8 481 SUPERFAMILY SSF51905 2 473 9.85E-64 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_07480 21375735516f8214d6a5168e138acd59 326 Pfam PF12679 ABC-2 family transporter protein 3 325 2.1E-20 T 11-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 AFK25_09755 39fc8e4ec6d0d5d6f94b3c5a941ad0e2 332 Gene3D G3DSA:3.40.50.970 1 332 6.1E-122 T 11-10-2018 AFK25_09755 39fc8e4ec6d0d5d6f94b3c5a941ad0e2 332 SUPERFAMILY SSF52518 7 330 1.14E-104 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold AFK25_09755 39fc8e4ec6d0d5d6f94b3c5a941ad0e2 332 Pfam PF00676 Dehydrogenase E1 component 21 320 6.3E-106 T 11-10-2018 IPR001017 Dehydrogenase, E1 component GO:0016624 Reactome: R-HSA-389661 AFK25_03045 fbe2270c040a58a0a8a0485529837052 1119 Pfam PF13558 Putative exonuclease SbcCD, C subunit 993 1074 8.7E-15 T 11-10-2018 AFK25_03045 fbe2270c040a58a0a8a0485529837052 1119 SUPERFAMILY SSF52540 20 1102 2.39E-27 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_03045 fbe2270c040a58a0a8a0485529837052 1119 Pfam PF13476 AAA domain 5 237 3.1E-13 T 11-10-2018 IPR038729 Rad50/SbcC-type AAA domain AFK25_03045 fbe2270c040a58a0a8a0485529837052 1119 Gene3D G3DSA:3.40.50.300 1 310 4.8E-44 T 11-10-2018 AFK25_03045 fbe2270c040a58a0a8a0485529837052 1119 Gene3D G3DSA:3.40.50.300 837 1115 6.1E-31 T 11-10-2018 AFK25_05455 035e28f80098fecfd0e4d7cb46243389 218 ProSitePatterns PS01085 Ribulose-phosphate 3-epimerase family signature 1. 31 45 - T 11-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 AFK25_05455 035e28f80098fecfd0e4d7cb46243389 218 Gene3D G3DSA:3.20.20.70 1 217 7.1E-92 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_05455 035e28f80098fecfd0e4d7cb46243389 218 Pfam PF00834 Ribulose-phosphate 3 epimerase family 3 200 7.8E-89 T 11-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 AFK25_05455 035e28f80098fecfd0e4d7cb46243389 218 SUPERFAMILY SSF51366 1 214 2.76E-77 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFK25_05455 035e28f80098fecfd0e4d7cb46243389 218 PIRSF PIRSF001461 1 218 2.4E-99 T 11-10-2018 IPR026019 Ribulose-phosphate 3-epimerase GO:0004750|GO:0006098 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 AFK25_05455 035e28f80098fecfd0e4d7cb46243389 218 TIGRFAM TIGR01163 rpe: ribulose-phosphate 3-epimerase 3 213 3.7E-93 T 11-10-2018 IPR000056 Ribulose-phosphate 3-epimerase-like GO:0005975|GO:0016857 KEGG: 00030+5.1.3.1|KEGG: 00040+5.1.3.1|KEGG: 00710+5.1.3.1|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-71336 AFK25_01890 c45bda94d7f12d6f7c3db9db02c75af8 548 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 3 546 8.2E-116 T 11-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 AFK25_01890 c45bda94d7f12d6f7c3db9db02c75af8 548 Pfam PF02652 L-lactate permease 5 543 3.3E-120 T 11-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 AFK25_12195 eef4e71181b29b5f469b687cca571cca 393 Gene3D G3DSA:3.40.50.300 1 227 9.2E-75 T 11-10-2018 AFK25_12195 eef4e71181b29b5f469b687cca571cca 393 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 4 208 3.7E-60 T 11-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain AFK25_12195 eef4e71181b29b5f469b687cca571cca 393 SMART SM00833 254 369 3.3E-53 T 11-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AFK25_12195 eef4e71181b29b5f469b687cca571cca 393 Pfam PF07683 Cobalamin synthesis protein cobW C-terminal domain 254 369 1.9E-28 T 11-10-2018 IPR011629 Cobalamin (vitamin B12) biosynthesis CobW-like, C-terminal AFK25_12195 eef4e71181b29b5f469b687cca571cca 393 SUPERFAMILY SSF52540 3 304 8.85E-45 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_01625 65d6643a35ec7452034b9c706df300cf 223 SMART SM00862 145 219 7.5E-26 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFK25_01625 65d6643a35ec7452034b9c706df300cf 223 Gene3D G3DSA:1.10.10.10 126 222 9.3E-31 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_01625 65d6643a35ec7452034b9c706df300cf 223 SUPERFAMILY SSF52172 1 166 9.25E-47 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_01625 65d6643a35ec7452034b9c706df300cf 223 Pfam PF00072 Response regulator receiver domain 4 113 6.8E-33 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_01625 65d6643a35ec7452034b9c706df300cf 223 Pfam PF00486 Transcriptional regulatory protein, C terminal 146 219 2.2E-24 T 11-10-2018 IPR001867 OmpR/PhoB-type DNA-binding domain GO:0000160|GO:0003677|GO:0006355 AFK25_01625 65d6643a35ec7452034b9c706df300cf 223 Gene3D G3DSA:3.40.50.2300 1 125 5.3E-43 T 11-10-2018 AFK25_01625 65d6643a35ec7452034b9c706df300cf 223 SMART SM00448 2 112 1.8E-47 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_08575 877a11daa0e9745883919ba1736fe62d 355 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 4 354 7.1E-55 T 11-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 AFK25_08575 877a11daa0e9745883919ba1736fe62d 355 Pfam PF03845 Spore germination protein 6 297 5.3E-27 T 11-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 AFK25_11995 ab9a6de70470cc929101e748feb78412 125 Pfam PF03788 LrgA family 16 107 9.4E-31 T 11-10-2018 IPR005538 LrgA/CidA family GO:0016021 AFK25_05265 ed0083efe04dffc6efb7f10c51a1911d 297 Pfam PF03419 Sporulation factor SpoIIGA 4 291 2.2E-89 T 11-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 AFK25_05265 ed0083efe04dffc6efb7f10c51a1911d 297 TIGRFAM TIGR02854 spore_II_GA: sigma-E processing peptidase SpoIIGA 3 291 9.3E-95 T 11-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 AFK25_05265 ed0083efe04dffc6efb7f10c51a1911d 297 PIRSF PIRSF018571 2 294 1.3E-88 T 11-10-2018 IPR005081 Sigma-E processing peptidase SpoIIGA GO:0004190|GO:0006508|GO:0030436 AFK25_14660 e6038271b1593e80b12dfdc7d1408b52 112 TIGRFAM TIGR00188 rnpA: ribonuclease P protein component 1 109 4.6E-33 T 11-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 AFK25_14660 e6038271b1593e80b12dfdc7d1408b52 112 SUPERFAMILY SSF54211 1 110 2.78E-34 T 11-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AFK25_14660 e6038271b1593e80b12dfdc7d1408b52 112 ProSitePatterns PS00648 Bacterial ribonuclease P protein component signature. 51 65 - T 11-10-2018 IPR020539 Ribonuclease P, conserved site GO:0004526 AFK25_14660 e6038271b1593e80b12dfdc7d1408b52 112 Gene3D G3DSA:3.30.230.10 1 112 6.9E-38 T 11-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AFK25_14660 e6038271b1593e80b12dfdc7d1408b52 112 ProDom PD003629 P RIBONUCLEASE COMPONENT HYDROLASE RNASE C5 RNASEP RNA-BINDING PROCESSING ENDONUCLEASE 7 101 1.0E-36 T 11-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 AFK25_14660 e6038271b1593e80b12dfdc7d1408b52 112 Hamap MF_00227 Ribonuclease P protein component [rnpA]. 1 111 21.03 T 11-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 AFK25_14660 e6038271b1593e80b12dfdc7d1408b52 112 Pfam PF00825 Ribonuclease P 1 108 1.8E-35 T 11-10-2018 IPR000100 Ribonuclease P GO:0000049|GO:0004526|GO:0008033 AFK25_02970 d8b2acee2da10ff6d51b3152fff9ea67 326 Pfam PF04392 ABC transporter substrate binding protein 36 322 5.5E-82 T 11-10-2018 IPR007487 ABC transporter, substrate-binding protein AFK25_02970 d8b2acee2da10ff6d51b3152fff9ea67 326 Gene3D G3DSA:3.40.50.2300 47 297 1.1E-91 T 11-10-2018 AFK25_02970 d8b2acee2da10ff6d51b3152fff9ea67 326 SUPERFAMILY SSF53822 43 296 2.04E-16 T 11-10-2018 IPR028082 Periplasmic binding protein-like I AFK25_02970 d8b2acee2da10ff6d51b3152fff9ea67 326 Gene3D G3DSA:3.40.50.2300 146 313 1.1E-91 T 11-10-2018 AFK25_04335 d24cacf06c4f1fbbfa5efd0e57f8658a 239 Pfam PF07729 FCD domain 102 226 4.2E-25 T 11-10-2018 IPR011711 GntR, C-terminal AFK25_04335 d24cacf06c4f1fbbfa5efd0e57f8658a 239 SMART SM00895 101 228 4.1E-23 T 11-10-2018 IPR011711 GntR, C-terminal AFK25_04335 d24cacf06c4f1fbbfa5efd0e57f8658a 239 SUPERFAMILY SSF48008 97 236 1.94E-30 T 11-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFK25_04335 d24cacf06c4f1fbbfa5efd0e57f8658a 239 Gene3D G3DSA:1.10.10.10 3 83 7.8E-23 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_04335 d24cacf06c4f1fbbfa5efd0e57f8658a 239 Gene3D G3DSA:1.20.120.530 84 236 5.1E-31 T 11-10-2018 IPR008920 Transcription regulator FadR/GntR, C-terminal AFK25_04335 d24cacf06c4f1fbbfa5efd0e57f8658a 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 50 66 8.3E-6 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_04335 d24cacf06c4f1fbbfa5efd0e57f8658a 239 PRINTS PR00035 GntR bacterial regulatory protein HTH signature 36 50 8.3E-6 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_04335 d24cacf06c4f1fbbfa5efd0e57f8658a 239 SMART SM00345 17 76 3.8E-20 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_04335 d24cacf06c4f1fbbfa5efd0e57f8658a 239 SUPERFAMILY SSF46785 7 86 2.24E-21 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_04335 d24cacf06c4f1fbbfa5efd0e57f8658a 239 Pfam PF00392 Bacterial regulatory proteins, gntR family 14 76 6.2E-19 T 11-10-2018 IPR000524 Transcription regulator HTH, GntR GO:0003700|GO:0006355 AFK25_05250 62161211682b83abd3b64fa5b68b520b 119 Pfam PF06947 Protein of unknown function (DUF1290) 22 107 8.0E-36 T 11-10-2018 IPR009709 Protein of unknown function DUF1290 AFK25_05250 62161211682b83abd3b64fa5b68b520b 119 PIRSF PIRSF018579 1 113 2.4E-47 T 11-10-2018 IPR009709 Protein of unknown function DUF1290 AFK25_11015 bf626e7797850adbb7daea4dc9b85e08 403 Pfam PF00482 Type II secretion system (T2SS), protein F 272 393 2.0E-27 T 11-10-2018 IPR018076 Type II secretion system F domain AFK25_11015 bf626e7797850adbb7daea4dc9b85e08 403 Pfam PF00482 Type II secretion system (T2SS), protein F 68 191 4.0E-34 T 11-10-2018 IPR018076 Type II secretion system F domain AFK25_11015 bf626e7797850adbb7daea4dc9b85e08 403 Gene3D G3DSA:1.20.81.30 54 170 8.8E-33 T 11-10-2018 AFK25_11015 bf626e7797850adbb7daea4dc9b85e08 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 382 401 1.3E-18 T 11-10-2018 IPR003004 GspF/PilC family AFK25_11015 bf626e7797850adbb7daea4dc9b85e08 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 163 191 1.3E-18 T 11-10-2018 IPR003004 GspF/PilC family AFK25_11015 bf626e7797850adbb7daea4dc9b85e08 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 64 76 1.3E-18 T 11-10-2018 IPR003004 GspF/PilC family AFK25_11015 bf626e7797850adbb7daea4dc9b85e08 403 PRINTS PR00812 Bacterial general secretion pathway protein F signature 366 380 1.3E-18 T 11-10-2018 IPR003004 GspF/PilC family AFK25_11015 bf626e7797850adbb7daea4dc9b85e08 403 Gene3D G3DSA:1.20.81.30 254 365 1.5E-30 T 11-10-2018 AFK25_11015 bf626e7797850adbb7daea4dc9b85e08 403 ProSitePatterns PS00874 Bacterial type II secretion system protein F signature. 163 191 - T 11-10-2018 IPR001992 Type II secretion system conserved site GO:0009306|GO:0016020 AFK25_05550 434c5b16f102ac5f83f21ab77276c7a4 90 Pfam PF00886 Ribosomal protein S16 9 67 1.7E-26 T 11-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_05550 434c5b16f102ac5f83f21ab77276c7a4 90 Gene3D G3DSA:3.30.1320.10 1 90 3.7E-38 T 11-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_05550 434c5b16f102ac5f83f21ab77276c7a4 90 ProSitePatterns PS00732 Ribosomal protein S16 signature. 3 12 - T 11-10-2018 IPR020592 Ribosomal protein S16, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AFK25_05550 434c5b16f102ac5f83f21ab77276c7a4 90 Hamap MF_00385 30S ribosomal protein S16 [rpsP]. 2 77 25.367 T 11-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_05550 434c5b16f102ac5f83f21ab77276c7a4 90 TIGRFAM TIGR00002 S16: ribosomal protein bS16 3 79 2.8E-36 T 11-10-2018 IPR000307 Ribosomal protein S16 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_05550 434c5b16f102ac5f83f21ab77276c7a4 90 SUPERFAMILY SSF54565 2 87 6.41E-36 T 11-10-2018 IPR023803 Ribosomal protein S16 domain superfamily Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_01955 98413d5110398f8b5d4d10f0bcdb94a5 357 Pfam PF06081 Aromatic acid exporter family member 1 1 142 1.3E-42 T 11-10-2018 IPR010343 Aromatic acid exporter family member 1 AFK25_14205 2fd8699d8f9f87194f52db3f27903226 56 Pfam PF07235 Protein of unknown function (DUF1427) 4 46 7.9E-8 T 11-10-2018 IPR009872 Protein of unknown function DUF1427 AFK25_14205 2fd8699d8f9f87194f52db3f27903226 56 TIGRFAM TIGR03510 XapX: XapX domain 3 50 6.8E-20 T 11-10-2018 IPR020017 XapX domain AFK25_01880 f4e55917f47e31bcf80bf6613ba6c218 266 Gene3D G3DSA:1.10.10.10 111 155 5.6E-16 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_01880 f4e55917f47e31bcf80bf6613ba6c218 266 Pfam PF02631 RecX family 87 207 6.3E-24 T 11-10-2018 IPR003783 Regulatory protein RecX GO:0006282 AFK25_01880 f4e55917f47e31bcf80bf6613ba6c218 266 Gene3D G3DSA:1.10.10.10 156 213 8.3E-9 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_01880 f4e55917f47e31bcf80bf6613ba6c218 266 Gene3D G3DSA:1.10.10.10 214 266 4.0E-12 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_01880 f4e55917f47e31bcf80bf6613ba6c218 266 Hamap MF_01114 Regulatory protein RecX [recX]. 45 212 15.763 T 11-10-2018 IPR003783 Regulatory protein RecX GO:0006282 AFK25_01880 f4e55917f47e31bcf80bf6613ba6c218 266 Gene3D G3DSA:1.10.10.2800 1 110 1.6E-27 T 11-10-2018 AFK25_13430 f8e56c1fbf687791e028d741f7a4fb45 213 SUPERFAMILY SSF46894 147 212 7.48E-18 T 11-10-2018 IPR016032 Signal transduction response regulator, C-terminal effector GO:0003677|GO:0006355 AFK25_13430 f8e56c1fbf687791e028d741f7a4fb45 213 SUPERFAMILY SSF52172 4 139 5.55E-26 T 11-10-2018 IPR011006 CheY-like superfamily AFK25_13430 f8e56c1fbf687791e028d741f7a4fb45 213 Gene3D G3DSA:3.40.50.12740 5 213 3.4E-50 T 11-10-2018 AFK25_13430 f8e56c1fbf687791e028d741f7a4fb45 213 SMART SM00448 5 118 3.2E-21 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_13430 f8e56c1fbf687791e028d741f7a4fb45 213 SMART SM00421 150 207 2.0E-17 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_13430 f8e56c1fbf687791e028d741f7a4fb45 213 Pfam PF00196 Bacterial regulatory proteins, luxR family 152 207 7.3E-16 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_13430 f8e56c1fbf687791e028d741f7a4fb45 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 167 183 2.0E-11 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_13430 f8e56c1fbf687791e028d741f7a4fb45 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 153 167 2.0E-11 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_13430 f8e56c1fbf687791e028d741f7a4fb45 213 PRINTS PR00038 LuxR bacterial regulatory protein HTH signature 183 195 2.0E-11 T 11-10-2018 IPR000792 Transcription regulator LuxR, C-terminal GO:0006355 AFK25_13430 f8e56c1fbf687791e028d741f7a4fb45 213 Pfam PF00072 Response regulator receiver domain 7 118 1.5E-20 T 11-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AFK25_02210 2d817f3150b7aeba3e24493a7de61495 157 Hamap MF_01885 tRNA (cytidine(34)-2'-O)-methyltransferase [trmL]. 3 154 34.7 T 11-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 AFK25_02210 2d817f3150b7aeba3e24493a7de61495 157 SUPERFAMILY SSF75217 3 155 1.77E-46 T 11-10-2018 IPR029028 Alpha/beta knot methyltransferases AFK25_02210 2d817f3150b7aeba3e24493a7de61495 157 PIRSF PIRSF029256 2 156 1.0E-68 T 11-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 AFK25_02210 2d817f3150b7aeba3e24493a7de61495 157 TIGRFAM TIGR00185 tRNA_yibK_trmL: tRNA (cytidine(34)-2'-O)-methyltransferase 2 155 1.0E-67 T 11-10-2018 IPR016914 tRNA (cytidine/uridine-2'-O-)-methyltransferase GO:0001510|GO:0008168 AFK25_02210 2d817f3150b7aeba3e24493a7de61495 157 Pfam PF00588 SpoU rRNA Methylase family 3 145 3.1E-35 T 11-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AFK25_02210 2d817f3150b7aeba3e24493a7de61495 157 Gene3D G3DSA:3.40.1280.10 1 157 4.3E-69 T 11-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AFK25_06955 afea395d190bc5c9e65a2ea75609140f 220 Gene3D G3DSA:3.30.420.10 74 213 2.5E-20 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFK25_06955 afea395d190bc5c9e65a2ea75609140f 220 SUPERFAMILY SSF53098 73 209 1.15E-14 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_06955 afea395d190bc5c9e65a2ea75609140f 220 Pfam PF13456 Reverse transcriptase-like 78 204 5.3E-13 T 11-10-2018 IPR002156 Ribonuclease H domain GO:0003676|GO:0004523 AFK25_10620 ca858883053c1ec657b5ee505f69e56b 212 SUPERFAMILY SSF53335 7 198 1.92E-35 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_10620 ca858883053c1ec657b5ee505f69e56b 212 Pfam PF13649 Methyltransferase domain 49 139 1.9E-17 T 11-10-2018 AFK25_10620 ca858883053c1ec657b5ee505f69e56b 212 Gene3D G3DSA:3.40.50.150 24 212 2.2E-49 T 11-10-2018 AFK25_10620 ca858883053c1ec657b5ee505f69e56b 212 Hamap MF_02100 Uncharacterized methyltransferase . 2 212 46.922 T 11-10-2018 IPR023553 Uncharacterised methyltransferase, YrrT GO:0008168 AFK25_00200 74ef4a1d3ace58571855494fce1566c9 244 Pfam PF05175 Methyltransferase small domain 17 127 1.5E-10 T 11-10-2018 IPR007848 Methyltransferase small domain GO:0008168 AFK25_00200 74ef4a1d3ace58571855494fce1566c9 244 Gene3D G3DSA:3.40.50.150 6 244 3.2E-76 T 11-10-2018 AFK25_00200 74ef4a1d3ace58571855494fce1566c9 244 SUPERFAMILY SSF53335 13 196 9.28E-34 T 11-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AFK25_06085 6d2dd4bf8423bea90b5686bdfc716477 889 Gene3D G3DSA:3.40.50.300 5 250 1.5E-10 T 11-10-2018 AFK25_06085 6d2dd4bf8423bea90b5686bdfc716477 889 SUPERFAMILY SSF52540 64 421 3.17E-16 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_06085 6d2dd4bf8423bea90b5686bdfc716477 889 Gene3D G3DSA:3.40.50.300 251 454 1.4E-26 T 11-10-2018 AFK25_06085 6d2dd4bf8423bea90b5686bdfc716477 889 Pfam PF00271 Helicase conserved C-terminal domain 313 419 2.7E-5 T 11-10-2018 IPR001650 Helicase, C-terminal AFK25_06085 6d2dd4bf8423bea90b5686bdfc716477 889 Pfam PF04851 Type III restriction enzyme, res subunit 12 233 4.2E-28 T 11-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AFK25_13255 6425d1ab7c7d2bc5d166028ad9aa0689 89 Pfam PF04316 Anti-sigma-28 factor, FlgM 32 80 4.6E-11 T 11-10-2018 IPR031316 Anti-sigma-28 factor FlgM, C-terminal AFK25_13255 6425d1ab7c7d2bc5d166028ad9aa0689 89 TIGRFAM TIGR03824 FlgM_jcvi: flagellar biosynthesis anti-sigma factor FlgM 23 84 3.5E-11 T 11-10-2018 IPR007412 Anti-sigma-28 factor, FlgM GO:0045892 AFK25_13255 6425d1ab7c7d2bc5d166028ad9aa0689 89 SUPERFAMILY SSF101498 1 84 1.44E-16 T 11-10-2018 IPR035890 Anti-sigma-28 factor FlgM superfamily AFK25_10310 6d9881aa82723232af67bfbd964aa498 128 Gene3D G3DSA:1.10.3830.10 1 117 4.1E-40 T 11-10-2018 IPR036945 Diacylglycerol kinase (DAGK) superfamily GO:0008610|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 AFK25_10310 6d9881aa82723232af67bfbd964aa498 128 Pfam PF01219 Prokaryotic diacylglycerol kinase 12 112 2.4E-36 T 11-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 AFK25_10310 6d9881aa82723232af67bfbd964aa498 128 ProSitePatterns PS01069 Prokaryotic diacylglycerol kinase signature. 65 76 - T 11-10-2018 IPR000829 DAGK family GO:0008654|GO:0016020|GO:0016301 KEGG: 00561+2.7.1.107|KEGG: 00564+2.7.1.107|KEGG: 04070+2.7.1.107|MetaCyc: PWY-7039|MetaCyc: PWY-7817 AFK25_06325 970e4238e3d9053ac30c1366dfaf8b6a 170 Gene3D G3DSA:1.20.1260.50 1 160 2.8E-8 T 11-10-2018 AFK25_03435 cfaddd497d1f61363836264a94a92eda 240 Pfam PF10026 Predicted Zn-dependent protease (DUF2268) 50 237 5.6E-57 T 11-10-2018 IPR018728 Domain of unknown function DUF2268 AFK25_08495 48141a96e2787d3216bf1c2391386706 482 Pfam PF13005 zinc-finger binding domain of transposase IS66 117 161 4.2E-12 T 11-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 AFK25_08495 48141a96e2787d3216bf1c2391386706 482 Pfam PF03050 Transposase IS66 family 177 443 6.6E-62 T 11-10-2018 IPR004291 Transposase, IS66 AFK25_10500 87b26cc4966315d5719d1f987dfb85ab 46 Pfam PF08970 Sporulation inhibitor A 1 44 1.7E-22 T 11-10-2018 IPR015064 Sporulation inhibitor A AFK25_10500 87b26cc4966315d5719d1f987dfb85ab 46 Gene3D G3DSA:1.10.287.1100 4 37 3.5E-17 T 11-10-2018 IPR036916 Sporulation inhibitor A superfamily AFK25_10500 87b26cc4966315d5719d1f987dfb85ab 46 SUPERFAMILY SSF100985 1 45 3.4E-15 T 11-10-2018 IPR036916 Sporulation inhibitor A superfamily AFK25_03010 e4e372a8dc3113e76107f814abd58f8f 415 Gene3D G3DSA:3.30.2010.10 203 285 2.6E-25 T 11-10-2018 AFK25_03010 e4e372a8dc3113e76107f814abd58f8f 415 Pfam PF16491 CAAX prenyl protease N-terminal, five membrane helices 47 203 8.1E-18 T 11-10-2018 IPR032456 CAAX prenyl protease 1, N-terminal KEGG: 00900+3.4.24.84 AFK25_03010 e4e372a8dc3113e76107f814abd58f8f 415 Pfam PF01435 Peptidase family M48 207 413 8.6E-33 T 11-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AFK25_13730 bb90d2cae38f32b65b3ee1c2910bf0a3 274 Pfam PF06429 Flagellar basal body rod FlgEFG protein C-terminal 193 270 2.0E-13 T 11-10-2018 IPR010930 Flagellar basal-body/hook protein, C-terminal domain AFK25_13730 bb90d2cae38f32b65b3ee1c2910bf0a3 274 TIGRFAM TIGR03506 FlgEFG_subfam: flagellar hook-basal body protein 4 142 4.4E-29 T 11-10-2018 IPR020013 Flagellar hook-basal body protein, FlgE/F/G AFK25_13730 bb90d2cae38f32b65b3ee1c2910bf0a3 274 SUPERFAMILY SSF117143 92 234 1.31E-14 T 11-10-2018 IPR037925 Flagellar hook-basal body protein, FlgE/F/G-like AFK25_13730 bb90d2cae38f32b65b3ee1c2910bf0a3 274 Pfam PF00460 Flagella basal body rod protein 7 35 3.6E-11 T 11-10-2018 IPR001444 Flagellar basal body rod protein, N-terminal GO:0071973 AFK25_08770 b7002562b4412c32b0a3fb0a263d8da8 127 Hamap MF_00446 Aspartate 1-decarboxylase [panD]. 1 127 71.823 T 11-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFK25_08770 b7002562b4412c32b0a3fb0a263d8da8 127 Pfam PF02261 Aspartate decarboxylase 1 114 9.4E-52 T 11-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFK25_08770 b7002562b4412c32b0a3fb0a263d8da8 127 SUPERFAMILY SSF50692 1 120 3.56E-49 T 11-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AFK25_08770 b7002562b4412c32b0a3fb0a263d8da8 127 Gene3D G3DSA:2.40.40.20 1 125 1.3E-53 T 11-10-2018 AFK25_08770 b7002562b4412c32b0a3fb0a263d8da8 127 PIRSF PIRSF006246 1 126 4.7E-53 T 11-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFK25_08770 b7002562b4412c32b0a3fb0a263d8da8 127 ProDom PD009294 ASPARTATE 1-DECARBOXYLASE DECARBOXYLASE CHAIN LYASE ALPHA ALPHA- CONTAINS: PRECURSOR BETA 5 95 1.0E-43 T 11-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFK25_08770 b7002562b4412c32b0a3fb0a263d8da8 127 TIGRFAM TIGR00223 panD: aspartate 1-decarboxylase 1 125 5.9E-57 T 11-10-2018 IPR003190 Aspartate decarboxylase GO:0004068|GO:0006523 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AFK25_14040 85510506b9d437bf01a07af1c74dd777 145 SUPERFAMILY SSF50814 5 142 1.99E-31 T 11-10-2018 IPR012674 Calycin AFK25_14040 85510506b9d437bf01a07af1c74dd777 145 Pfam PF09148 Domain of unknown function (DUF1934) 15 138 6.1E-25 T 11-10-2018 IPR015231 Protein of unknown function DUF1934 AFK25_14040 85510506b9d437bf01a07af1c74dd777 145 Gene3D G3DSA:2.40.128.20 3 145 4.3E-37 T 11-10-2018 IPR012674 Calycin AFK25_13605 cf05b2d18524d41689cfa731267f92e9 376 Pfam PF05225 helix-turn-helix, Psq domain 285 322 5.4E-7 T 11-10-2018 IPR007889 DNA binding HTH domain, Psq-type GO:0003677 AFK25_13605 cf05b2d18524d41689cfa731267f92e9 376 Gene3D G3DSA:3.10.450.50 1 26 2.7E-6 T 11-10-2018 AFK25_13605 cf05b2d18524d41689cfa731267f92e9 376 SUPERFAMILY SSF103642 5 24 2.45E-7 T 11-10-2018 AFK25_13605 cf05b2d18524d41689cfa731267f92e9 376 Pfam PF02810 SEC-C motif 6 23 1.4E-9 T 11-10-2018 IPR004027 SEC-C motif AFK25_02870 98b20642bdf66185e16f7b537c6ba86a 168 Gene3D G3DSA:3.30.70.3430 1 166 2.3E-63 T 11-10-2018 AFK25_02870 98b20642bdf66185e16f7b537c6ba86a 168 Pfam PF03992 Antibiotic biosynthesis monooxygenase 65 138 1.3E-15 T 11-10-2018 IPR007138 Antibiotic biosynthesis monooxygenase domain AFK25_02870 98b20642bdf66185e16f7b537c6ba86a 168 SUPERFAMILY SSF54909 65 165 1.51E-23 T 11-10-2018 IPR011008 Dimeric alpha-beta barrel AFK25_08220 e5ab2207181b1f947c9444d26220f54c 429 Pfam PF06782 Uncharacterised protein family (UPF0236) 2 427 5.0E-136 T 11-10-2018 IPR009620 Uncharacterised protein family UPF0236 AFK25_03295 2021ef951c40fe6ece6a9d79f293f8ce 341 TIGRFAM TIGR03160 cobT_DBIPRT: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 4 333 5.1E-137 T 11-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 AFK25_03295 2021ef951c40fe6ece6a9d79f293f8ce 341 SUPERFAMILY SSF52733 6 333 2.75E-117 T 11-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 AFK25_03295 2021ef951c40fe6ece6a9d79f293f8ce 341 Gene3D G3DSA:1.10.1610.10 13 333 1.6E-136 T 11-10-2018 IPR023195 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, N-terminal GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 AFK25_03295 2021ef951c40fe6ece6a9d79f293f8ce 341 Gene3D G3DSA:3.40.50.10210 45 317 1.6E-136 T 11-10-2018 AFK25_03295 2021ef951c40fe6ece6a9d79f293f8ce 341 Pfam PF02277 Phosphoribosyltransferase 4 333 1.3E-134 T 11-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 AFK25_03295 2021ef951c40fe6ece6a9d79f293f8ce 341 Hamap MF_00230 Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase [cobT]. 1 335 36.135 T 11-10-2018 IPR017846 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, prokaryotic GO:0008939|GO:0009163 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 AFK25_10940 ffdc41ba2b9a5421aef86e2349c1db9f 243 SUPERFAMILY SSF51261 98 238 2.62E-18 T 11-10-2018 IPR011055 Duplicated hybrid motif AFK25_10940 ffdc41ba2b9a5421aef86e2349c1db9f 243 Pfam PF01551 Peptidase family M23 145 236 8.8E-18 T 11-10-2018 IPR016047 Peptidase M23 AFK25_10940 ffdc41ba2b9a5421aef86e2349c1db9f 243 Gene3D G3DSA:2.70.70.10 116 241 4.3E-18 T 11-10-2018 IPR011055 Duplicated hybrid motif AFK25_04340 da55cf0da435ac6fcf02db1c3b97dd9c 238 Hamap MF_02105 Lactate utilization protein A [lutA]. 1 238 63.147 T 11-10-2018 IPR022822 Lactate utilization protein A GO:0006089 AFK25_04340 da55cf0da435ac6fcf02db1c3b97dd9c 238 Pfam PF02754 Cysteine-rich domain 132 215 1.5E-15 T 11-10-2018 IPR004017 Cysteine-rich domain AFK25_04340 da55cf0da435ac6fcf02db1c3b97dd9c 238 Pfam PF02754 Cysteine-rich domain 3 84 1.5E-17 T 11-10-2018 IPR004017 Cysteine-rich domain AFK25_02935 7eec225595e88f77ba48f93834328d2b 100 TIGRFAM TIGR03647 Na_symport_sm: putative solute:sodium symporter small subunit 12 86 1.7E-27 T 11-10-2018 IPR019886 Sodium symporter small subunit, predicted AFK25_02935 7eec225595e88f77ba48f93834328d2b 100 Pfam PF13937 Domain of unknown function (DUF4212) 10 84 2.4E-28 T 11-10-2018 IPR019886 Sodium symporter small subunit, predicted AFK25_13290 00f83c4cb05f3704d3627dc838a3ad35 280 SUPERFAMILY SSF82549 1 280 1.57E-97 T 11-10-2018 AFK25_13290 00f83c4cb05f3704d3627dc838a3ad35 280 Gene3D G3DSA:3.30.1180.10 152 280 2.6E-46 T 11-10-2018 AFK25_13290 00f83c4cb05f3704d3627dc838a3ad35 280 Gene3D G3DSA:3.40.50.10170 1 151 1.0E-54 T 11-10-2018 AFK25_13290 00f83c4cb05f3704d3627dc838a3ad35 280 Pfam PF02645 Uncharacterised protein, DegV family COG1307 2 279 2.1E-99 T 11-10-2018 IPR003797 DegV AFK25_13290 00f83c4cb05f3704d3627dc838a3ad35 280 TIGRFAM TIGR00762 DegV: EDD domain protein, DegV family 4 278 3.4E-107 T 11-10-2018 IPR003797 DegV AFK25_14110 54deddf1c3aa5907e1a4f5609c4ace36 274 SUPERFAMILY SSF55681 4 264 1.66E-71 T 11-10-2018 AFK25_14110 54deddf1c3aa5907e1a4f5609c4ace36 274 Hamap MF_02119 Lipoyl-[GcvH]:protein N-lipoyltransferase [lipL]. 3 273 52.484 T 11-10-2018 IPR024897 Octanoyltransferase LipL GO:0009107|GO:0009249|GO:0016415 MetaCyc: PWY-6987 AFK25_14110 54deddf1c3aa5907e1a4f5609c4ace36 274 Gene3D G3DSA:3.30.930.10 3 274 7.4E-87 T 11-10-2018 AFK25_14110 54deddf1c3aa5907e1a4f5609c4ace36 274 Pfam PF03099 Biotin/lipoate A/B protein ligase family 75 179 7.4E-13 T 11-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 AFK25_09025 4858eaf2d5f585387c53d69f4ae742b2 59 ProDom PD052359 YPFB 1 55 1.0E-4 T 11-10-2018 IPR035281 Protein of unknown function DUF5359 AFK25_09025 4858eaf2d5f585387c53d69f4ae742b2 59 Pfam PF17313 Family of unknown function (DUF5359) 1 56 2.9E-27 T 11-10-2018 IPR035281 Protein of unknown function DUF5359 AFK25_08085 f1fb51ad990766edc7ac0d5dd52a872c 308 Pfam PF12146 Serine aminopeptidase, S33 84 202 1.2E-11 T 11-10-2018 IPR022742 Serine aminopeptidase, S33 AFK25_08085 f1fb51ad990766edc7ac0d5dd52a872c 308 Gene3D G3DSA:3.40.50.1820 61 308 3.6E-44 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold AFK25_08085 f1fb51ad990766edc7ac0d5dd52a872c 308 SUPERFAMILY SSF53474 20 306 4.81E-49 T 11-10-2018 IPR029058 Alpha/Beta hydrolase fold AFK25_03170 d158dcfe4c77f9fc4f9d3fd518b8c21c 450 TIGRFAM TIGR00797 matE: MATE efflux family protein 16 415 2.7E-56 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFK25_03170 d158dcfe4c77f9fc4f9d3fd518b8c21c 450 PIRSF PIRSF006603 3 450 2.8E-86 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFK25_03170 d158dcfe4c77f9fc4f9d3fd518b8c21c 450 Pfam PF01554 MatE 241 402 3.4E-30 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFK25_03170 d158dcfe4c77f9fc4f9d3fd518b8c21c 450 Pfam PF01554 MatE 16 175 3.9E-29 T 11-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AFK25_03560 a4b3dd9192bbcf7aac68e9ea484bdd82 245 PRINTS PR00114 Serine/threonine phosphatase family signature 2 29 8.3E-5 T 11-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFK25_03560 a4b3dd9192bbcf7aac68e9ea484bdd82 245 PRINTS PR00114 Serine/threonine phosphatase family signature 40 67 8.3E-5 T 11-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AFK25_03560 a4b3dd9192bbcf7aac68e9ea484bdd82 245 Hamap MF_01443 Bis(5'-nucleosyl)-tetraphosphatase PrpE [asymmetrical] [prpE]. 1 245 58.186 T 11-10-2018 IPR023937 Bis(5'-nucleosyl)-tetraphosphatase PrpE GO:0004081|GO:0016151 KEGG: 00230+3.6.1.17|KEGG: 00240+3.6.1.17 AFK25_03560 a4b3dd9192bbcf7aac68e9ea484bdd82 245 Pfam PF00149 Calcineurin-like phosphoesterase 5 196 6.2E-13 T 11-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AFK25_03560 a4b3dd9192bbcf7aac68e9ea484bdd82 245 Gene3D G3DSA:3.60.21.10 2 244 1.9E-68 T 11-10-2018 IPR029052 Metallo-dependent phosphatase-like AFK25_03560 a4b3dd9192bbcf7aac68e9ea484bdd82 245 SUPERFAMILY SSF56300 4 224 1.73E-44 T 11-10-2018 AFK25_11570 e1c9ac49b782f1c6ff355f849887cfa1 198 SUPERFAMILY SSF52540 2 187 7.63E-46 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_11570 e1c9ac49b782f1c6ff355f849887cfa1 198 Pfam PF01121 Dephospho-CoA kinase 1 180 1.7E-64 T 11-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 AFK25_11570 e1c9ac49b782f1c6ff355f849887cfa1 198 Hamap MF_00376 Dephospho-CoA kinase [coaE]. 1 196 28.199 T 11-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 AFK25_11570 e1c9ac49b782f1c6ff355f849887cfa1 198 TIGRFAM TIGR00152 TIGR00152: dephospho-CoA kinase 1 187 2.5E-67 T 11-10-2018 IPR001977 Dephospho-CoA kinase GO:0004140|GO:0005524|GO:0015937 KEGG: 00770+2.7.1.24|MetaCyc: PWY-7851 AFK25_11570 e1c9ac49b782f1c6ff355f849887cfa1 198 Gene3D G3DSA:3.40.50.300 1 194 1.4E-82 T 11-10-2018 AFK25_13750 e3465f6ca0d2fb1c008c3ebc70879ac1 258 Pfam PF01551 Peptidase family M23 111 209 8.8E-27 T 11-10-2018 IPR016047 Peptidase M23 AFK25_13750 e3465f6ca0d2fb1c008c3ebc70879ac1 258 SUPERFAMILY SSF51261 105 212 1.88E-29 T 11-10-2018 IPR011055 Duplicated hybrid motif AFK25_13750 e3465f6ca0d2fb1c008c3ebc70879ac1 258 Gene3D G3DSA:2.70.70.10 68 241 1.3E-50 T 11-10-2018 IPR011055 Duplicated hybrid motif AFK25_06195 b9eba43e48a8f9fc7371d955db4b919d 141 Gene3D G3DSA:3.90.79.10 1 140 1.7E-22 T 11-10-2018 AFK25_06195 b9eba43e48a8f9fc7371d955db4b919d 141 SUPERFAMILY SSF55811 2 131 4.2E-19 T 11-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AFK25_06195 b9eba43e48a8f9fc7371d955db4b919d 141 ProSitePatterns PS00893 Nudix box signature. 40 61 - T 11-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AFK25_06195 b9eba43e48a8f9fc7371d955db4b919d 141 Pfam PF00293 NUDIX domain 5 134 1.5E-13 T 11-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AFK25_12555 c0c3cb9f2b2d3cc366ff57cabdc1702c 107 Pfam PF14068 Putative membrane protein 8 107 5.0E-39 T 11-10-2018 IPR025917 Putative membrane protein YuiB AFK25_00420 55ddfb5283ece04339e76321a40851b2 178 Pfam PF01288 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) 6 133 2.6E-39 T 11-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 AFK25_00420 55ddfb5283ece04339e76321a40851b2 178 ProSitePatterns PS00794 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase signature. 89 100 - T 11-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 AFK25_00420 55ddfb5283ece04339e76321a40851b2 178 SUPERFAMILY SSF55083 3 160 5.62E-57 T 11-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 AFK25_00420 55ddfb5283ece04339e76321a40851b2 178 Gene3D G3DSA:3.30.70.560 2 176 8.7E-59 T 11-10-2018 IPR035907 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK superfamily KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 AFK25_00420 55ddfb5283ece04339e76321a40851b2 178 TIGRFAM TIGR01498 folK: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase 5 133 3.8E-48 T 11-10-2018 IPR000550 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK GO:0003848|GO:0009396 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 AFK25_04685 0ef4b59c5bdee2edcf581dbc56e7daa2 78 Gene3D G3DSA:4.10.810.10 18 74 1.8E-13 T 11-10-2018 IPR027393 Virus scaffolding protein, C-terminal GO:0005515 AFK25_04685 0ef4b59c5bdee2edcf581dbc56e7daa2 78 Pfam PF08858 IDEAL domain 27 63 4.1E-13 T 11-10-2018 IPR014957 IDEAL domain AFK25_04685 0ef4b59c5bdee2edcf581dbc56e7daa2 78 SMART SM00914 27 63 2.4E-9 T 11-10-2018 IPR014957 IDEAL domain AFK25_12080 8aa349fb7e72fd961bc7eb914569e3cf 176 Gene3D G3DSA:2.160.10.10 1 175 6.8E-78 T 11-10-2018 AFK25_12080 8aa349fb7e72fd961bc7eb914569e3cf 176 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 11 44 1.6E-5 T 11-10-2018 IPR001451 Hexapeptide repeat AFK25_12080 8aa349fb7e72fd961bc7eb914569e3cf 176 Pfam PF00132 Bacterial transferase hexapeptide (six repeats) 88 120 3.1E-5 T 11-10-2018 IPR001451 Hexapeptide repeat AFK25_12080 8aa349fb7e72fd961bc7eb914569e3cf 176 SUPERFAMILY SSF51161 2 168 1.8E-49 T 11-10-2018 IPR011004 Trimeric LpxA-like superfamily AFK25_01065 6f97b6d50c2d186741553d722421d493 358 Pfam PF03845 Spore germination protein 5 315 3.1E-33 T 11-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 AFK25_01065 6f97b6d50c2d186741553d722421d493 358 TIGRFAM TIGR00912 2A0309: spore germination protein (amino acid permease) 2 347 8.4E-67 T 11-10-2018 IPR004761 Spore germination GerAB GO:0009847|GO:0016021 AFK25_06380 eaf83bfe99e879570b48e47716221428 255 PIRSF PIRSF033101 3 255 2.8E-74 T 11-10-2018 IPR011397 Uncharacterised conserved protein UCP033101 AFK25_06380 eaf83bfe99e879570b48e47716221428 255 Pfam PF10086 Putative membrane peptidase family (DUF2324) 17 237 6.7E-70 T 11-10-2018 IPR011397 Uncharacterised conserved protein UCP033101 AFK25_09455 9c85dadd28e342b3e3d7f076cc64686a 214 PIRSF PIRSF038973 1 213 2.3E-75 T 11-10-2018 IPR014196 Stage II sporulation protein M AFK25_09455 9c85dadd28e342b3e3d7f076cc64686a 214 TIGRFAM TIGR02831 spo_II_M: stage II sporulation protein M 12 206 5.4E-75 T 11-10-2018 IPR014196 Stage II sporulation protein M AFK25_09455 9c85dadd28e342b3e3d7f076cc64686a 214 Pfam PF01944 Stage II sporulation protein M 25 202 9.3E-24 T 11-10-2018 IPR002798 Stage II sporulation protein M-like AFK25_07430 d778613a89b6035230de0509ea573d45 297 Pfam PF00892 EamA-like transporter family 147 282 3.2E-21 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFK25_07430 d778613a89b6035230de0509ea573d45 297 Pfam PF00892 EamA-like transporter family 3 137 2.4E-19 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFK25_07430 d778613a89b6035230de0509ea573d45 297 SUPERFAMILY SSF103481 184 284 9.94E-14 T 11-10-2018 AFK25_07430 d778613a89b6035230de0509ea573d45 297 SUPERFAMILY SSF103481 38 138 4.97E-17 T 11-10-2018 AFK25_11745 1504b3c64cb959a253900aaea82bd106 142 PIRSF PIRSF021377 1 141 2.5E-65 T 11-10-2018 IPR014229 Sporulation protein YtfJ AFK25_11745 1504b3c64cb959a253900aaea82bd106 142 TIGRFAM TIGR02874 spore_ytfJ: sporulation protein YtfJ 4 127 4.8E-58 T 11-10-2018 IPR014229 Sporulation protein YtfJ AFK25_11745 1504b3c64cb959a253900aaea82bd106 142 Pfam PF09579 Sporulation protein YtfJ (Spore_YtfJ) 31 118 4.4E-29 T 11-10-2018 IPR014229 Sporulation protein YtfJ AFK25_06615 cc98cf069b983196e4586675c8016fe1 345 PIRSF PIRSF000112 1 344 3.5E-74 T 11-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 AFK25_06615 cc98cf069b983196e4586675c8016fe1 345 SUPERFAMILY SSF56796 6 324 8.37E-52 T 11-10-2018 AFK25_06615 cc98cf069b983196e4586675c8016fe1 345 Gene3D G3DSA:1.20.1090.10 152 345 1.2E-50 T 11-10-2018 AFK25_06615 cc98cf069b983196e4586675c8016fe1 345 Gene3D G3DSA:3.40.50.1970 1 150 1.4E-32 T 11-10-2018 AFK25_06615 cc98cf069b983196e4586675c8016fe1 345 Pfam PF13685 Iron-containing alcohol dehydrogenase 10 263 1.0E-72 T 11-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 AFK25_06190 8a26bbfc97990dcb470e9cd52e2adab9 123 SUPERFAMILY SSF54593 5 121 1.03E-19 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFK25_06190 8a26bbfc97990dcb470e9cd52e2adab9 123 Gene3D G3DSA:3.10.180.10 9 122 5.7E-30 T 11-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AFK25_06190 8a26bbfc97990dcb470e9cd52e2adab9 123 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 8 118 2.0E-5 T 11-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AFK25_12070 9f50b61beb8834536a331f49dabac606 356 Pfam PF10776 Protein of unknown function (DUF2600) 20 348 1.6E-155 T 11-10-2018 IPR019712 Protein of unknown function DUF2600 AFK25_08880 f2d15a2621573c5ce4f306c9738c4fd8 280 SUPERFAMILY SSF51366 2 229 2.83E-77 T 11-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AFK25_08880 f2d15a2621573c5ce4f306c9738c4fd8 280 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 1 254 33.282 T 11-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFK25_08880 f2d15a2621573c5ce4f306c9738c4fd8 280 Pfam PF00290 Tryptophan synthase alpha chain 2 240 5.3E-89 T 11-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFK25_08880 f2d15a2621573c5ce4f306c9738c4fd8 280 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 33 46 - T 11-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFK25_08880 f2d15a2621573c5ce4f306c9738c4fd8 280 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 2 250 2.9E-84 T 11-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AFK25_08880 f2d15a2621573c5ce4f306c9738c4fd8 280 Gene3D G3DSA:3.20.20.70 1 256 1.4E-91 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_06650 ee78ea5a7a484f0e225268a7ca0a856b 325 Pfam PF03773 Predicted permease 43 323 2.6E-70 T 11-10-2018 IPR005524 Predicted permease DUF318 AFK25_06395 c212fa559f1d58590c0d52b1ac854673 562 ProSitePatterns PS00722 Formate--tetrahydrofolate ligase signature 2. 334 345 - T 11-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 AFK25_06395 c212fa559f1d58590c0d52b1ac854673 562 Gene3D G3DSA:3.30.1510.10 135 253 2.2E-207 T 11-10-2018 AFK25_06395 c212fa559f1d58590c0d52b1ac854673 562 ProSitePatterns PS00721 Formate--tetrahydrofolate ligase signature 1. 109 119 - T 11-10-2018 IPR020628 Formate-tetrahydrofolate ligase, FTHFS, conserved site GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 AFK25_06395 c212fa559f1d58590c0d52b1ac854673 562 Hamap MF_01543 Formate--tetrahydrofolate ligase [fhs]. 7 562 49.101 T 11-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 AFK25_06395 c212fa559f1d58590c0d52b1ac854673 562 Gene3D G3DSA:3.10.410.10 449 538 3.6E-36 T 11-10-2018 AFK25_06395 c212fa559f1d58590c0d52b1ac854673 562 Gene3D G3DSA:3.40.50.300 12 443 2.2E-207 T 11-10-2018 AFK25_06395 c212fa559f1d58590c0d52b1ac854673 562 SUPERFAMILY SSF52540 10 560 1.79E-247 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_06395 c212fa559f1d58590c0d52b1ac854673 562 Pfam PF01268 Formate--tetrahydrofolate ligase 8 562 1.4E-272 T 11-10-2018 IPR000559 Formate-tetrahydrofolate ligase, FTHFS GO:0004329|GO:0005524 KEGG: 00670+6.3.4.3|KEGG: 00720+6.3.4.3|MetaCyc: PWY-1722|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3841|Reactome: R-HSA-196757 AFK25_06050 0c1a136abb3284418b0b8a75a8c34a4e 124 Pfam PF13248 zinc-ribbon domain 99 122 3.7E-8 T 11-10-2018 AFK25_04780 77fadd57a95dce075baed9ee6c807f43 128 Pfam PF02537 CrcB-like protein, Camphor Resistance (CrcB) 6 112 1.1E-24 T 11-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 AFK25_04780 77fadd57a95dce075baed9ee6c807f43 128 Hamap MF_00454 Putative fluoride ion transporter CrcB [crcB]. 4 117 17.82 T 11-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 AFK25_04780 77fadd57a95dce075baed9ee6c807f43 128 TIGRFAM TIGR00494 crcB: protein CrcB 6 114 1.2E-23 T 11-10-2018 IPR003691 Putative fluoride ion transporter CrcB GO:0016021 AFK25_07545 8056b330b3b2d04663bb8b88f37d0c06 402 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 18 303 2.3E-88 T 11-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AFK25_07545 8056b330b3b2d04663bb8b88f37d0c06 402 TIGRFAM TIGR01127 ilvA_1Cterm: threonine ammonia-lyase 21 398 7.1E-152 T 11-10-2018 IPR005789 Threonine dehydratase, catabolic GO:0004794|GO:0006567 KEGG: 00260+4.3.1.19|KEGG: 00290+4.3.1.19 AFK25_07545 8056b330b3b2d04663bb8b88f37d0c06 402 Gene3D G3DSA:3.40.50.1100 7 308 4.7E-126 T 11-10-2018 AFK25_07545 8056b330b3b2d04663bb8b88f37d0c06 402 Gene3D G3DSA:3.40.50.1100 50 146 4.7E-126 T 11-10-2018 AFK25_07545 8056b330b3b2d04663bb8b88f37d0c06 402 SUPERFAMILY SSF53686 4 353 4.45E-104 T 11-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AFK25_07545 8056b330b3b2d04663bb8b88f37d0c06 402 Gene3D G3DSA:3.30.70.260 326 402 1.8E-6 T 11-10-2018 AFK25_02615 0bb62bcc65b4465e45e43260599f961b 142 Gene3D G3DSA:3.10.580.10 2 132 1.3E-42 T 11-10-2018 AFK25_02615 0bb62bcc65b4465e45e43260599f961b 142 SUPERFAMILY SSF54631 4 120 5.56E-38 T 11-10-2018 AFK25_02615 0bb62bcc65b4465e45e43260599f961b 142 Pfam PF00571 CBS domain 6 55 3.1E-17 T 11-10-2018 IPR000644 CBS domain AFK25_02615 0bb62bcc65b4465e45e43260599f961b 142 Pfam PF00571 CBS domain 70 121 2.5E-12 T 11-10-2018 IPR000644 CBS domain AFK25_02615 0bb62bcc65b4465e45e43260599f961b 142 SMART SM00116 77 124 1.0E-11 T 11-10-2018 IPR000644 CBS domain AFK25_02615 0bb62bcc65b4465e45e43260599f961b 142 SMART SM00116 13 60 6.2E-14 T 11-10-2018 IPR000644 CBS domain AFK25_01115 5f4e7d04dcfebe4542d969ab0cb490e4 151 Hamap MF_00745 Protein SprT-like. 4 147 39.685 T 11-10-2018 IPR023524 Uncharacterised protein family SprT-like AFK25_01115 5f4e7d04dcfebe4542d969ab0cb490e4 151 Pfam PF10263 SprT-like family 7 97 2.2E-14 T 11-10-2018 IPR006640 SprT-like AFK25_01115 5f4e7d04dcfebe4542d969ab0cb490e4 151 SMART SM00731 4 147 5.8E-54 T 11-10-2018 IPR006640 SprT-like AFK25_02825 e4cde47f42c2127889184e24a8c15e68 113 Pfam PF08963 Protein of unknown function (DUF1878) 2 108 8.7E-47 T 11-10-2018 IPR015058 Protein of unknown function DUF1878 AFK25_02825 e4cde47f42c2127889184e24a8c15e68 113 ProDom PD073069 YHAI 3D-STRUCTURE 9 100 9.0E-26 T 11-10-2018 IPR015058 Protein of unknown function DUF1878 AFK25_02825 e4cde47f42c2127889184e24a8c15e68 113 SUPERFAMILY SSF109915 1 110 1.7E-41 T 11-10-2018 IPR035945 YhaI-like superfamily AFK25_02825 e4cde47f42c2127889184e24a8c15e68 113 Gene3D G3DSA:1.10.3750.10 1 113 4.5E-39 T 11-10-2018 IPR035945 YhaI-like superfamily AFK25_14115 a4a041b4a298f7dd2b7bba25ea0de7fc 327 PIRSF PIRSF000428 1 325 9.9E-109 T 11-10-2018 IPR012147 Phosphate acetyl/butyryltransferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFK25_14115 a4a041b4a298f7dd2b7bba25ea0de7fc 327 Gene3D G3DSA:3.40.50.10950 18 319 7.5E-134 T 11-10-2018 AFK25_14115 a4a041b4a298f7dd2b7bba25ea0de7fc 327 TIGRFAM TIGR00651 pta: phosphate acetyltransferase 19 319 1.4E-128 T 11-10-2018 IPR004614 Phosphate acetyltransferase GO:0016407 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFK25_14115 a4a041b4a298f7dd2b7bba25ea0de7fc 327 Pfam PF01515 Phosphate acetyl/butaryl transferase 7 319 4.0E-127 T 11-10-2018 IPR002505 Phosphate acetyl/butaryl transferase GO:0016746 KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AFK25_14115 a4a041b4a298f7dd2b7bba25ea0de7fc 327 Gene3D G3DSA:3.40.50.10750 142 295 7.5E-134 T 11-10-2018 AFK25_14115 a4a041b4a298f7dd2b7bba25ea0de7fc 327 SUPERFAMILY SSF53659 6 322 1.44E-94 T 11-10-2018 AFK25_12015 de0ea8dfb5f2a4e55189e5cc40b10dd4 73 SUPERFAMILY SSF46785 11 60 4.8E-8 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_12015 de0ea8dfb5f2a4e55189e5cc40b10dd4 73 SMART SM00420 11 63 0.0042 T 11-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFK25_12015 de0ea8dfb5f2a4e55189e5cc40b10dd4 73 Gene3D G3DSA:1.10.10.10 10 71 2.5E-7 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_12015 de0ea8dfb5f2a4e55189e5cc40b10dd4 73 Pfam PF08220 DeoR-like helix-turn-helix domain 11 54 1.4E-9 T 11-10-2018 IPR001034 DeoR-type HTH domain GO:0003700|GO:0005622|GO:0006355 AFK25_05040 4128957f16d378d76188548d30db2ec5 289 TIGRFAM TIGR02737 caa3_CtaG: cytochrome c oxidase assembly factor CtaG 4 277 3.5E-126 T 11-10-2018 IPR014108 Cytochrome c oxidase caa3 type assembly factor CtaG AFK25_05040 4128957f16d378d76188548d30db2ec5 289 Pfam PF09678 Cytochrome c oxidase caa3 assembly factor (Caa3_CtaG) 27 276 9.4E-67 T 11-10-2018 IPR019108 Cytochrome c oxidase caa3-type, assembly factor CtaG-related AFK25_09885 9f4f4152730d4e30c45411a39037568f 129 Pfam PF06686 Stage III sporulation protein AC/AD protein family 1 55 2.0E-13 T 11-10-2018 IPR025664 Stage III sporulation protein AC/AD family AFK25_09885 9f4f4152730d4e30c45411a39037568f 129 Pfam PF06686 Stage III sporulation protein AC/AD protein family 69 123 1.6E-19 T 11-10-2018 IPR025664 Stage III sporulation protein AC/AD family AFK25_09885 9f4f4152730d4e30c45411a39037568f 129 TIGRFAM TIGR02849 spore_III_AD: stage III sporulation protein AD 25 125 8.5E-38 T 11-10-2018 IPR014211 Stage III sporulation protein AD AFK25_00895 6f499ae8456084b7f285888182c4f767 410 Gene3D G3DSA:2.170.120.30 319 410 2.5E-15 T 11-10-2018 AFK25_00895 6f499ae8456084b7f285888182c4f767 410 Gene3D G3DSA:2.170.120.30 36 140 1.6E-28 T 11-10-2018 AFK25_00895 6f499ae8456084b7f285888182c4f767 410 Pfam PF07949 YbbR-like protein 233 310 5.3E-14 T 11-10-2018 IPR012505 YbbR-like AFK25_00895 6f499ae8456084b7f285888182c4f767 410 Pfam PF07949 YbbR-like protein 141 224 7.5E-12 T 11-10-2018 IPR012505 YbbR-like AFK25_00895 6f499ae8456084b7f285888182c4f767 410 Pfam PF07949 YbbR-like protein 51 131 5.5E-11 T 11-10-2018 IPR012505 YbbR-like AFK25_00895 6f499ae8456084b7f285888182c4f767 410 Gene3D G3DSA:2.170.120.40 141 227 8.9E-7 T 11-10-2018 AFK25_00895 6f499ae8456084b7f285888182c4f767 410 Gene3D G3DSA:2.170.120.40 230 316 4.7E-19 T 11-10-2018 AFK25_01420 17f31d18843ecfd85fc0927e195339d7 160 SUPERFAMILY SSF57997 13 151 1.9E-6 T 11-10-2018 AFK25_01420 17f31d18843ecfd85fc0927e195339d7 160 Gene3D G3DSA:1.20.5.340 3 129 1.7E-10 T 11-10-2018 AFK25_01420 17f31d18843ecfd85fc0927e195339d7 160 Pfam PF10046 Biogenesis of lysosome-related organelles complex-1 subunit 2 9 83 4.4E-7 T 11-10-2018 IPR019269 Biogenesis of lysosome-related organelles complex-1, subunit 2 AFK25_08375 e269b4c4a00ed3cbf96aecd1063e7aca 138 Pfam PF14343 PrcB C-terminal 71 128 2.9E-16 T 11-10-2018 IPR025748 PrcB C-terminal domain AFK25_12550 c9277cfc714a2b83a20491b76fe2faf5 235 Pfam PF06725 3D domain 136 197 4.0E-19 T 11-10-2018 IPR010611 3D domain GO:0004553|GO:0009254|GO:0019867 AFK25_12550 c9277cfc714a2b83a20491b76fe2faf5 235 SUPERFAMILY SSF50685 136 178 2.62E-7 T 11-10-2018 IPR036908 RlpA-like domain superfamily AFK25_03055 73629273b13e0a65defce0f50f1aa91f 73 Pfam PF10676 Spore germination protein gerPA/gerPF 1 72 7.1E-27 T 11-10-2018 IPR019618 Spore germination protein GerPA/GerPF AFK25_07040 dc81a61db2f8a382251aaec1413405fa 366 Pfam PF01757 Acyltransferase family 8 333 1.1E-22 T 11-10-2018 IPR002656 Acyltransferase 3 GO:0016747 AFK25_09245 f1bf498483643e4c117f619efb893e33 177 Pfam PF07670 Nucleoside recognition 46 146 4.1E-7 T 11-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 AFK25_06235 f32429f0cecb93b8b254176716743245 327 Pfam PF00578 AhpC/TSA family 191 309 3.5E-32 T 11-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AFK25_06235 f32429f0cecb93b8b254176716743245 327 SUPERFAMILY SSF52833 189 324 1.96E-43 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_06235 f32429f0cecb93b8b254176716743245 327 ProSitePatterns PS00194 Thioredoxin family active site. 219 237 - T 11-10-2018 IPR017937 Thioredoxin, conserved site GO:0045454 AFK25_06235 f32429f0cecb93b8b254176716743245 327 Gene3D G3DSA:3.40.30.10 168 327 3.1E-48 T 11-10-2018 AFK25_09565 9a8fff197450df2b863b058bb5fd75cb 253 Gene3D G3DSA:3.40.190.10 108 209 2.8E-72 T 11-10-2018 AFK25_09565 9a8fff197450df2b863b058bb5fd75cb 253 SUPERFAMILY SSF53850 28 250 3.82E-62 T 11-10-2018 AFK25_09565 9a8fff197450df2b863b058bb5fd75cb 253 Gene3D G3DSA:3.40.190.10 33 247 2.8E-72 T 11-10-2018 AFK25_09565 9a8fff197450df2b863b058bb5fd75cb 253 Pfam PF13531 Bacterial extracellular solute-binding protein 29 247 1.5E-52 T 11-10-2018 AFK25_09565 9a8fff197450df2b863b058bb5fd75cb 253 PIRSF PIRSF004846 2 251 1.1E-66 T 11-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 AFK25_09565 9a8fff197450df2b863b058bb5fd75cb 253 TIGRFAM TIGR01256 modA: molybdate ABC transporter, periplasmic molybdate-binding protein 34 246 1.8E-64 T 11-10-2018 IPR005950 Molybdate ABC transporter, substrate-binding protein GO:0015689 AFK25_10785 93054aa16e6f98aaad318365fdd4496b 297 SUPERFAMILY SSF161111 7 214 2.22E-53 T 11-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFK25_10785 93054aa16e6f98aaad318365fdd4496b 297 SUPERFAMILY SSF160240 219 295 2.88E-17 T 11-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AFK25_10785 93054aa16e6f98aaad318365fdd4496b 297 Pfam PF01545 Cation efflux family 15 209 1.2E-45 T 11-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFK25_10785 93054aa16e6f98aaad318365fdd4496b 297 Gene3D G3DSA:1.20.1510.10 10 213 1.3E-60 T 11-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AFK25_10785 93054aa16e6f98aaad318365fdd4496b 297 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 13 295 1.4E-71 T 11-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AFK25_10785 93054aa16e6f98aaad318365fdd4496b 297 Pfam PF16916 Dimerisation domain of Zinc Transporter 219 294 1.9E-19 T 11-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain AFK25_10785 93054aa16e6f98aaad318365fdd4496b 297 Gene3D G3DSA:3.30.70.1350 216 295 1.2E-14 T 11-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AFK25_12085 a276072501cb826a7b3f070bfe10a421 172 SMART SM00014 61 168 1.1E-20 T 11-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFK25_12085 a276072501cb826a7b3f070bfe10a421 172 Gene3D G3DSA:1.20.144.10 6 95 5.0E-6 T 11-10-2018 AFK25_12085 a276072501cb826a7b3f070bfe10a421 172 Gene3D G3DSA:1.20.144.10 96 172 3.2E-18 T 11-10-2018 AFK25_12085 a276072501cb826a7b3f070bfe10a421 172 Pfam PF01569 PAP2 superfamily 61 169 5.8E-20 T 11-10-2018 IPR000326 Phosphatidic acid phosphatase type 2/haloperoxidase AFK25_12085 a276072501cb826a7b3f070bfe10a421 172 SUPERFAMILY SSF48317 6 170 8.9E-37 T 11-10-2018 IPR036938 Phosphatidic acid phosphatase type 2/haloperoxidase superfamily AFK25_05035 dc7740548890bc52a0b29353fc5d4a65 110 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 30 101 6.0E-15 T 11-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 AFK25_05035 dc7740548890bc52a0b29353fc5d4a65 110 TIGRFAM TIGR02908 CoxD_Bacillus: cytochrome c oxidase, subunit IVB 1 109 1.0E-52 T 11-10-2018 IPR014257 Cytochrome c oxidase, subunit IV bacillaceae KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279 AFK25_09160 bdc37694306ee3f77626a43e01044962 156 Pfam PF12822 ECF transporter, substrate-specific component 2 137 1.5E-9 T 11-10-2018 IPR024529 ECF transporter, substrate-specific component GO:0005215 AFK25_09160 bdc37694306ee3f77626a43e01044962 156 Gene3D G3DSA:1.10.1760.20 1 155 2.2E-15 T 11-10-2018 AFK25_02315 73c7e59856db57955e8b8712f861c990 69 Pfam PF17356 Phage-like element PBSX protein XtrA 4 69 2.7E-19 T 11-10-2018 IPR035530 Phage-like element PBSX protein XtrA AFK25_02315 73c7e59856db57955e8b8712f861c990 69 ProDom PD027572 XTRA PBSX RELATED YQAO ELEMENT PHAGE PHAGE-LIKE 13 64 1.0E-21 T 11-10-2018 IPR035530 Phage-like element PBSX protein XtrA AFK25_13385 8330d57f1759b571984d76961d5622e3 80 TIGRFAM TIGR03949 bact_IIb_cerein: class IIb bacteriocin, lactobin A/cerein 7B family 11 50 2.5E-7 T 11-10-2018 IPR023991 Bacteriocin, class IIb, lactobin A/cerein 7B family AFK25_13385 8330d57f1759b571984d76961d5622e3 80 Pfam PF10439 Bacteriocin class II with double-glycine leader peptide 8 76 6.1E-16 T 11-10-2018 IPR019493 Bacteriocin, class IIb, lactacin-related GO:0042742 AFK25_02005 846be2d4c217486f849106ba61e3eb5e 290 ProDom PD128250 YGXA BH0953 1 277 3.0E-87 T 11-10-2018 AFK25_02005 846be2d4c217486f849106ba61e3eb5e 290 Pfam PF14540 Nucleotidyltransferase-like 1 118 1.8E-47 T 11-10-2018 IPR029348 Nucleotidyltransferase-like domain AFK25_02005 846be2d4c217486f849106ba61e3eb5e 290 Gene3D G3DSA:1.20.120.330 115 232 2.5E-49 T 11-10-2018 AFK25_02005 846be2d4c217486f849106ba61e3eb5e 290 Gene3D G3DSA:3.30.460.10 1 114 2.3E-45 T 11-10-2018 AFK25_07415 2b48a389663351e10a97b726371eefd8 118 SUPERFAMILY SSF52540 2 70 7.9E-16 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_07415 2b48a389663351e10a97b726371eefd8 118 Pfam PF00005 ABC transporter 18 84 3.6E-11 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_07415 2b48a389663351e10a97b726371eefd8 118 Gene3D G3DSA:3.40.50.300 1 79 2.1E-15 T 11-10-2018 AFK25_04505 0f5b217d3130e131847e227a3a2d2c33 277 Gene3D G3DSA:1.20.5.170 54 108 2.9E-6 T 11-10-2018 AFK25_02375 72503f926721728ab052d2a9ebfcc243 607 Gene3D G3DSA:3.40.50.300 29 222 9.9E-16 T 11-10-2018 AFK25_02375 72503f926721728ab052d2a9ebfcc243 607 Pfam PF05876 Phage terminase large subunit (GpA) 39 572 2.9E-194 T 11-10-2018 IPR008866 Bacteriophage lambda, GpA AFK25_06370 21e095470450bf0a2f20d300068dd58e 92 SMART SM00418 5 83 7.1E-30 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_06370 21e095470450bf0a2f20d300068dd58e 92 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 7 22 1.6E-15 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_06370 21e095470450bf0a2f20d300068dd58e 92 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 39 54 1.6E-15 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_06370 21e095470450bf0a2f20d300068dd58e 92 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 54 69 1.6E-15 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_06370 21e095470450bf0a2f20d300068dd58e 92 Gene3D G3DSA:1.10.10.10 2 91 7.1E-30 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_06370 21e095470450bf0a2f20d300068dd58e 92 Pfam PF01022 Bacterial regulatory protein, arsR family 12 57 3.9E-18 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_06370 21e095470450bf0a2f20d300068dd58e 92 SUPERFAMILY SSF46785 4 84 2.99E-29 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_09835 567135bac5a3166f20a3e9c2f271ca95 449 Pfam PF02601 Exonuclease VII, large subunit 125 439 1.0E-106 T 11-10-2018 IPR020579 Exonuclease VII, large subunit, C-terminal GO:0008855 AFK25_09835 567135bac5a3166f20a3e9c2f271ca95 449 Pfam PF13742 OB-fold nucleic acid binding domain 8 102 1.8E-31 T 11-10-2018 IPR025824 OB-fold nucleic acid binding domain GO:0003676 AFK25_09835 567135bac5a3166f20a3e9c2f271ca95 449 TIGRFAM TIGR00237 xseA: exodeoxyribonuclease VII, large subunit 8 357 5.5E-146 T 11-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 AFK25_09835 567135bac5a3166f20a3e9c2f271ca95 449 Hamap MF_00378 Exodeoxyribonuclease 7 large subunit [xseA]. 4 442 31.265 T 11-10-2018 IPR003753 Exonuclease VII, large subunit GO:0006308|GO:0008855|GO:0009318 AFK25_11985 98eaa65eca9ad2bcc8adc4910c5a58c6 318 PIRSF PIRSF012560 1 316 2.6E-112 T 11-10-2018 IPR012397 Pullulan 6-glucanohydrolase AFK25_06655 2c90ca06c59f62e6e8fc3f3bd4de6603 284 TIGRFAM TIGR03943 TIGR03943: TIGR03943 family protein 19 280 2.4E-61 T 11-10-2018 IPR015402 Protein of unknown function DUF1980 AFK25_06655 2c90ca06c59f62e6e8fc3f3bd4de6603 284 Pfam PF09323 Domain of unknown function (DUF1980) 1 192 3.2E-38 T 11-10-2018 IPR015402 Protein of unknown function DUF1980 AFK25_12855 8f9ebd4651971424c4883b474052e459 309 Gene3D G3DSA:3.40.50.1980 26 132 5.3E-22 T 11-10-2018 AFK25_12855 8f9ebd4651971424c4883b474052e459 309 Gene3D G3DSA:3.40.50.1980 133 302 1.4E-44 T 11-10-2018 AFK25_12855 8f9ebd4651971424c4883b474052e459 309 Pfam PF01497 Periplasmic binding protein 50 279 7.6E-38 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain AFK25_12855 8f9ebd4651971424c4883b474052e459 309 SUPERFAMILY SSF53807 27 286 1.33E-59 T 11-10-2018 AFK25_10515 c5057525663e2069f044f445570fc9d6 266 Pfam PF01618 MotA/TolQ/ExbB proton channel family 103 218 1.6E-27 T 11-10-2018 IPR002898 MotA/TolQ/ExbB proton channel AFK25_10515 c5057525663e2069f044f445570fc9d6 266 ProSitePatterns PS01307 Flagellar motor protein motA family signature. 186 203 - T 11-10-2018 IPR000540 Flagellar motor protein MotA, conserved site AFK25_11095 487562ad640be0118ca8422e787b79ca 431 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 237 273 - T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFK25_11095 487562ad640be0118ca8422e787b79ca 431 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 7 426 1.2E-200 T 11-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 AFK25_11095 487562ad640be0118ca8422e787b79ca 431 Pfam PF00202 Aminotransferase class-III 35 419 6.0E-78 T 11-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AFK25_11095 487562ad640be0118ca8422e787b79ca 431 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 6 427 104.656 T 11-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 AFK25_11095 487562ad640be0118ca8422e787b79ca 431 Gene3D G3DSA:3.90.1150.10 10 421 2.3E-183 T 11-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AFK25_11095 487562ad640be0118ca8422e787b79ca 431 SUPERFAMILY SSF53383 4 426 1.24E-134 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_11095 487562ad640be0118ca8422e787b79ca 431 Gene3D G3DSA:3.40.640.10 72 319 2.3E-183 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_02630 d46657f434a29582d1af1aa174be5e2c 83 Pfam PF14148 YhdB-like protein 2 70 2.0E-38 T 11-10-2018 IPR025431 YhdB-like protein AFK25_05130 3547dae1e11294fd1ead33d89afb03b0 401 Pfam PF07670 Nucleoside recognition 43 132 1.1E-5 T 11-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 AFK25_05130 3547dae1e11294fd1ead33d89afb03b0 401 TIGRFAM TIGR02871 spore_ylbJ: sporulation integral membrane protein YlbJ 8 353 6.0E-127 T 11-10-2018 IPR014226 Sporulation integral membrane protein YlbJ AFK25_06055 b0e58fb501f0b806c5f46e3f823b19d8 220 Pfam PF06161 Protein of unknown function (DUF975) 126 210 1.8E-25 T 11-10-2018 IPR010380 Protein of unknown function DUF975 AFK25_06055 b0e58fb501f0b806c5f46e3f823b19d8 220 Pfam PF06161 Protein of unknown function (DUF975) 2 133 1.8E-12 T 11-10-2018 IPR010380 Protein of unknown function DUF975 AFK25_06775 7622626fcf0ace7f535ffd27cb7a39e4 144 Gene3D G3DSA:1.20.1500.10 1 124 1.1E-36 T 11-10-2018 IPR023378 YheA/YmcA-like domain superfamily AFK25_06775 7622626fcf0ace7f535ffd27cb7a39e4 144 SUPERFAMILY SSF158622 4 123 2.35E-36 T 11-10-2018 IPR023378 YheA/YmcA-like domain superfamily AFK25_06775 7622626fcf0ace7f535ffd27cb7a39e4 144 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 9 113 1.2E-23 T 11-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA AFK25_06775 7622626fcf0ace7f535ffd27cb7a39e4 144 PIRSF PIRSF021287 1 123 1.0E-49 T 11-10-2018 IPR016783 Biofilm formation YmcA AFK25_04965 78ec3f5d232df47660c4d0372c486b7a 66 Pfam PF09963 Uncharacterized protein conserved in bacteria (DUF2197) 1 56 3.5E-31 T 11-10-2018 IPR019241 Protein of unknown function DUF2197 AFK25_08685 886e52a8ef36ab9a1cb19de9ba87a3fa 106 Pfam PF14179 YppG-like protein 16 104 2.9E-19 T 11-10-2018 IPR025555 YppG-like protein AFK25_01555 055185e2bd133675388b649f5915ee72 292 Pfam PF13612 Transposase DDE domain 111 267 2.2E-24 T 11-10-2018 IPR025668 Transposase DDE domain AFK25_11965 62726b8debed0b0b496b6ec871dd06e8 89 Pfam PF14165 YtzH-like protein 3 88 8.3E-35 T 11-10-2018 IPR025547 YtzH-like protein AFK25_05245 3e9ddb97520e9b417177e065bc0280a7 238 Pfam PF05949 Bacterial protein of unknown function (DUF881) 86 230 3.3E-29 T 11-10-2018 IPR010273 Protein of unknown function DUF881 AFK25_05245 3e9ddb97520e9b417177e065bc0280a7 238 Gene3D G3DSA:3.30.70.1880 84 238 9.6E-15 T 11-10-2018 AFK25_02410 09a5e65e2f34ee10b1aca6ccf8a6e61d 109 Pfam PF13856 ATP-binding sugar transporter from pro-phage 1 101 8.1E-9 T 11-10-2018 IPR025601 ATP-binding sugar transporter-like protein AFK25_01845 17fd80f9558f1c8f31bf444e6f143a08 62 Pfam PF11127 Protein of unknown function (DUF2892) 1 61 2.3E-19 T 11-10-2018 IPR021309 Protein of unknown function DUF2892 AFK25_12845 c82bd64672a40bc7ee65dbc6ff8a6f19 263 SMART SM00382 26 215 2.1E-16 T 11-10-2018 IPR003593 AAA+ ATPase domain AFK25_12845 c82bd64672a40bc7ee65dbc6ff8a6f19 263 Gene3D G3DSA:3.40.50.300 1 247 1.6E-67 T 11-10-2018 AFK25_12845 c82bd64672a40bc7ee65dbc6ff8a6f19 263 SUPERFAMILY SSF52540 2 223 2.07E-62 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_12845 c82bd64672a40bc7ee65dbc6ff8a6f19 263 Pfam PF00005 ABC transporter 18 165 8.1E-34 T 11-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AFK25_12845 c82bd64672a40bc7ee65dbc6ff8a6f19 263 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 11-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AFK25_08565 803d28c532e1735539ab7e4e1ee5373f 370 Pfam PF05504 Spore germination B3/ GerAC like, C-terminal 219 331 1.6E-6 T 11-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 AFK25_08565 803d28c532e1735539ab7e4e1ee5373f 370 TIGRFAM TIGR02887 spore_ger_x_C: germination protein, Ger(x)C family 7 366 5.6E-58 T 11-10-2018 IPR008844 Spore germination GerAC GO:0009847|GO:0016020 AFK25_10080 00cf29bc1cb34a4d79ac37a0ccf43c8c 321 Gene3D G3DSA:3.30.420.40 129 302 3.0E-111 T 11-10-2018 AFK25_10080 00cf29bc1cb34a4d79ac37a0ccf43c8c 321 TIGRFAM TIGR00744 ROK_glcA_fam: ROK family protein (putative glucokinase) 6 321 2.2E-127 T 11-10-2018 IPR004654 Glucokinase ROK GO:0004340|GO:0005737|GO:0006096|GO:0051156 KEGG: 00010+2.7.1.2|KEGG: 00052+2.7.1.2|KEGG: 00500+2.7.1.2|KEGG: 00520+2.7.1.2|KEGG: 00521+2.7.1.2|KEGG: 00524+2.7.1.2|MetaCyc: PWY-2722|MetaCyc: PWY-2723|MetaCyc: PWY-5514|MetaCyc: PWY-5661|MetaCyc: PWY-621|MetaCyc: PWY-7238|MetaCyc: PWY-7385 AFK25_10080 00cf29bc1cb34a4d79ac37a0ccf43c8c 321 Gene3D G3DSA:3.30.420.40 6 314 3.0E-111 T 11-10-2018 AFK25_10080 00cf29bc1cb34a4d79ac37a0ccf43c8c 321 Pfam PF00480 ROK family 6 318 8.9E-77 T 11-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFK25_10080 00cf29bc1cb34a4d79ac37a0ccf43c8c 321 SUPERFAMILY SSF53067 4 317 1.33E-73 T 11-10-2018 AFK25_10080 00cf29bc1cb34a4d79ac37a0ccf43c8c 321 ProSitePatterns PS01125 ROK family signature. 138 165 - T 11-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AFK25_05490 d922becbb54b733f8dafef954a6b362f 295 Pfam PF03313 Serine dehydratase alpha chain 15 274 2.7E-76 T 11-10-2018 IPR005130 Serine dehydratase-like, alpha subunit AFK25_05490 d922becbb54b733f8dafef954a6b362f 295 TIGRFAM TIGR00718 sda_alpha: L-serine dehydratase, iron-sulfur-dependent, alpha subunit 1 291 2.4E-139 T 11-10-2018 IPR004642 Serine dehydratase, alpha subunit GO:0003941|GO:0006094 KEGG: 00260+4.3.1.17|KEGG: 00270+4.3.1.17 AFK25_02865 92272092a3e3ba8653d91f8efee6b413 122 Gene3D G3DSA:3.40.250.10 27 122 2.0E-30 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_02865 92272092a3e3ba8653d91f8efee6b413 122 SMART SM00450 30 122 1.0E-16 T 11-10-2018 IPR001763 Rhodanese-like domain AFK25_02865 92272092a3e3ba8653d91f8efee6b413 122 Pfam PF00581 Rhodanese-like domain 31 121 6.7E-16 T 11-10-2018 IPR001763 Rhodanese-like domain AFK25_02865 92272092a3e3ba8653d91f8efee6b413 122 SUPERFAMILY SSF52821 8 121 8.51E-33 T 11-10-2018 IPR036873 Rhodanese-like domain superfamily AFK25_13655 632b555c35736fad0074eae95137f25f 203 Pfam PF07929 Plasmid pRiA4b ORF-3-like protein 14 192 1.0E-60 T 11-10-2018 IPR012912 Plasmid pRiA4b, Orf3 AFK25_13655 632b555c35736fad0074eae95137f25f 203 Gene3D G3DSA:3.10.290.30 7 195 1.4E-65 T 11-10-2018 IPR024047 MM3350-like superfamily AFK25_13655 632b555c35736fad0074eae95137f25f 203 SUPERFAMILY SSF159941 12 194 4.97E-60 T 11-10-2018 IPR024047 MM3350-like superfamily AFK25_01530 05a08e37967c3b239204fbfcf80dd5a6 482 Pfam PF03050 Transposase IS66 family 177 443 7.8E-62 T 11-10-2018 IPR004291 Transposase, IS66 AFK25_01530 05a08e37967c3b239204fbfcf80dd5a6 482 Pfam PF13005 zinc-finger binding domain of transposase IS66 117 161 4.2E-12 T 11-10-2018 IPR024474 Zinc-finger binding domain of transposase IS66 AFK25_11550 2e96db151e8e33073d17a99a7b7ddbf5 156 TIGRFAM TIGR00244 TIGR00244: transcriptional regulator NrdR 1 147 9.7E-71 T 11-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 AFK25_11550 2e96db151e8e33073d17a99a7b7ddbf5 156 Hamap MF_00440 Transcriptional repressor NrdR [nrdR]. 1 153 89.076 T 11-10-2018 IPR003796 Ribonucleotide reductase regulator NrdR-like GO:0008270|GO:0045892 AFK25_11550 2e96db151e8e33073d17a99a7b7ddbf5 156 Pfam PF03477 ATP cone domain 50 136 4.1E-21 T 11-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 AFK25_10535 5966b6812b09bdba24382b8d20702ac0 261 SUPERFAMILY SSF81342 17 134 3.66E-6 T 11-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AFK25_10535 5966b6812b09bdba24382b8d20702ac0 261 Pfam PF14358 Domain of unknown function (DUF4405) 78 135 7.2E-13 T 11-10-2018 IPR025517 Domain of unknown function DUF4405 AFK25_04160 180786e22d9459dba7d8d5e6403f4594 101 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 5 96 2.1E-18 T 11-10-2018 IPR008407 Branched-chain amino acid transport, AzlD AFK25_08775 444b3b3e0f0bdf897d2516ec25bfcefb 282 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 26 85 4.7E-9 T 11-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AFK25_08775 444b3b3e0f0bdf897d2516ec25bfcefb 282 SUPERFAMILY SSF52374 2 280 3.75E-108 T 11-10-2018 AFK25_08775 444b3b3e0f0bdf897d2516ec25bfcefb 282 Pfam PF02569 Pantoate-beta-alanine ligase 3 277 7.9E-106 T 11-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 AFK25_08775 444b3b3e0f0bdf897d2516ec25bfcefb 282 Gene3D G3DSA:3.30.1300.10 178 277 5.6E-33 T 11-10-2018 AFK25_08775 444b3b3e0f0bdf897d2516ec25bfcefb 282 Gene3D G3DSA:3.40.50.620 1 177 2.1E-78 T 11-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AFK25_08775 444b3b3e0f0bdf897d2516ec25bfcefb 282 Hamap MF_00158 Pantothenate synthetase [panC]. 2 279 40.274 T 11-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 AFK25_08775 444b3b3e0f0bdf897d2516ec25bfcefb 282 TIGRFAM TIGR00018 panC: pantoate--beta-alanine ligase 2 279 8.0E-114 T 11-10-2018 IPR003721 Pantoate-beta-alanine ligase GO:0004592|GO:0015940 KEGG: 00410+6.3.2.1|KEGG: 00770+6.3.2.1 AFK25_09180 3784bdcbbe59874f356bb9ba01326581 249 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 249 35.124 T 11-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 AFK25_09180 3784bdcbbe59874f356bb9ba01326581 249 Pfam PF02654 Cobalamin-5-phosphate synthase 10 237 1.9E-47 T 11-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 AFK25_04310 eea7e28a59769e808df0ef69d812a0e8 111 Pfam PF13045 Protein of unknown function (DUF3905) 7 89 2.1E-43 T 11-10-2018 IPR024999 Protein of unknown function DUF3905 AFK25_11220 2bf597be2619ddc6daff51e76a4762ed 348 SMART SM00909 87 178 8.9E-25 T 11-10-2018 IPR019606 GerMN domain AFK25_11220 2bf597be2619ddc6daff51e76a4762ed 348 SMART SM00909 239 328 4.1E-22 T 11-10-2018 IPR019606 GerMN domain AFK25_11220 2bf597be2619ddc6daff51e76a4762ed 348 Pfam PF10646 Sporulation and spore germination 64 173 1.5E-20 T 11-10-2018 IPR019606 GerMN domain AFK25_11220 2bf597be2619ddc6daff51e76a4762ed 348 Pfam PF10646 Sporulation and spore germination 212 323 1.2E-16 T 11-10-2018 IPR019606 GerMN domain AFK25_14405 9fa64eefd5c858048bfa483f3c44d5db 430 Gene3D G3DSA:3.30.565.60 118 243 2.4E-14 T 11-10-2018 IPR038475 RecG, C-terminal domain superfamily AFK25_07405 b178b950003cb12f236a893f49c3d117 291 SUPERFAMILY SSF55729 1 287 2.23E-32 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFK25_07405 b178b950003cb12f236a893f49c3d117 291 Gene3D G3DSA:3.40.630.30 2 147 2.9E-24 T 11-10-2018 AFK25_07405 b178b950003cb12f236a893f49c3d117 291 Pfam PF13508 Acetyltransferase (GNAT) domain 53 134 2.8E-10 T 11-10-2018 IPR000182 GNAT domain AFK25_10185 53b3ffe2c152ac800293e38a9b360da9 257 Pfam PF06691 Protein of unknown function (DUF1189) 4 247 1.5E-70 T 11-10-2018 IPR009574 Protein of unknown function DUF1189 AFK25_01060 e6c70783d295ab1c17284e38b015e09c 487 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 11 474 2.6E-146 T 11-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 AFK25_01060 e6c70783d295ab1c17284e38b015e09c 487 PIRSF PIRSF005690 1 486 1.2E-141 T 11-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 AFK25_03500 c501b5eea60ddb1eef7ddeec024d884a 222 Gene3D G3DSA:3.30.70.1950 123 221 6.5E-30 T 11-10-2018 IPR038471 MecA, C-terminal domain superfamily AFK25_03500 c501b5eea60ddb1eef7ddeec024d884a 222 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 214 2.1E-48 T 11-10-2018 IPR008681 Negative regulator of genetic competence, MecA AFK25_03500 c501b5eea60ddb1eef7ddeec024d884a 222 PIRSF PIRSF029008 1 221 2.5E-72 T 11-10-2018 IPR008681 Negative regulator of genetic competence, MecA AFK25_03500 c501b5eea60ddb1eef7ddeec024d884a 222 Hamap MF_01124 Adapter protein MecA [mecA]. 1 219 26.027 T 11-10-2018 IPR008681 Negative regulator of genetic competence, MecA AFK25_00450 e02f6117ee6dcf5a681fe672ddee7dd5 153 Pfam PF05848 Firmicute transcriptional repressor of class III stress genes (CtsR) 3 150 1.0E-58 T 11-10-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355 AFK25_00450 e02f6117ee6dcf5a681fe672ddee7dd5 153 Gene3D G3DSA:1.10.1200.150 73 153 2.9E-32 T 11-10-2018 AFK25_00450 e02f6117ee6dcf5a681fe672ddee7dd5 153 PIRSF PIRSF010607 1 153 1.6E-67 T 11-10-2018 IPR008463 Transcriptional repressor of class III stress genes GO:0003677|GO:0006355 AFK25_00450 e02f6117ee6dcf5a681fe672ddee7dd5 153 Gene3D G3DSA:1.10.10.1240 2 72 6.1E-36 T 11-10-2018 AFK25_09675 64fa766ad7e01201483bc2845c7d67ef 105 PIRSF PIRSF017292 1 105 1.9E-36 T 11-10-2018 IPR016694 Protein of unknown function UCP017292, zinc finger, CHY-type AFK25_09675 64fa766ad7e01201483bc2845c7d67ef 105 SUPERFAMILY SSF161219 6 91 2.88E-15 T 11-10-2018 IPR037274 Zinc finger, CHY-type superfamily GO:0008270 Reactome: R-HSA-110320|Reactome: R-HSA-983168 AFK25_09675 64fa766ad7e01201483bc2845c7d67ef 105 Pfam PF05495 CHY zinc finger 15 89 4.8E-9 T 11-10-2018 IPR008913 Zinc finger, CHY-type GO:0008270 Reactome: R-HSA-110320|Reactome: R-HSA-983168 AFK25_01900 721e03f90f438a3754d2decd5ec00a99 55 TIGRFAM TIGR03091 SASP_sspK: small, acid-soluble spore protein K 16 47 3.0E-23 T 11-10-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 AFK25_01900 721e03f90f438a3754d2decd5ec00a99 55 Pfam PF08176 Small acid-soluble spore protein K family 2 47 5.2E-29 T 11-10-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 AFK25_01900 721e03f90f438a3754d2decd5ec00a99 55 Hamap MF_01504 Small, acid-soluble spore protein K [sspK]. 1 49 17.631 T 11-10-2018 IPR012611 Small acid-soluble spore protein, SspK GO:0030436|GO:0042601 AFK25_08850 1ae7c0b9d18a553ef4f369434a5a5325 144 Pfam PF10673 Protein of unknown function (DUF2487) 9 140 4.1E-47 T 11-10-2018 IPR019615 Protein of unknown function DUF2487 AFK25_10985 048ed4e0d57ce6714634413bf5608b03 146 Gene3D G3DSA:3.30.700.10 8 133 1.0E-9 T 11-10-2018 AFK25_10985 048ed4e0d57ce6714634413bf5608b03 146 ProSitePatterns PS00409 Prokaryotic N-terminal methylation site. 5 25 - T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_10985 048ed4e0d57ce6714634413bf5608b03 146 SUPERFAMILY SSF54523 7 93 5.89E-11 T 11-10-2018 AFK25_10985 048ed4e0d57ce6714634413bf5608b03 146 Pfam PF07963 Prokaryotic N-terminal methylation motif 1 26 7.9E-8 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_10985 048ed4e0d57ce6714634413bf5608b03 146 TIGRFAM TIGR02532 IV_pilin_GFxxxE: prepilin-type N-terminal cleavage/methylation domain 5 27 9.6E-8 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_07185 826b8e43c188d9fb9a042ccf68adf983 190 Gene3D G3DSA:3.40.30.10 20 188 1.0E-59 T 11-10-2018 AFK25_07185 826b8e43c188d9fb9a042ccf68adf983 190 Pfam PF02630 SCO1/SenC 11 171 1.3E-42 T 11-10-2018 IPR003782 Copper chaperone SCO1/SenC Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_07185 826b8e43c188d9fb9a042ccf68adf983 190 SUPERFAMILY SSF52833 28 188 1.07E-45 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_03085 a5670a54256201ae4cbe2ebf5715d8bc 74 Pfam PF10676 Spore germination protein gerPA/gerPF 1 70 8.2E-29 T 11-10-2018 IPR019618 Spore germination protein GerPA/GerPF AFK25_11155 8871c18f293b99303abe12300b739c02 306 Pfam PF14559 Tetratricopeptide repeat 23 84 1.7E-7 T 11-10-2018 AFK25_11155 8871c18f293b99303abe12300b739c02 306 SUPERFAMILY SSF116965 112 284 1.83E-16 T 11-10-2018 AFK25_11155 8871c18f293b99303abe12300b739c02 306 Pfam PF11428 Protein of unknown function (DUF3196) 144 284 2.7E-10 T 11-10-2018 IPR024503 Protein of unknown function DUF3196 AFK25_11155 8871c18f293b99303abe12300b739c02 306 SUPERFAMILY SSF48452 13 99 2.48E-8 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_11155 8871c18f293b99303abe12300b739c02 306 Gene3D G3DSA:1.25.40.10 13 83 5.5E-9 T 11-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AFK25_03330 d22dcb103d20a60935e3b36cffe8d13d 550 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 340 501 1.2E-33 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_03330 d22dcb103d20a60935e3b36cffe8d13d 550 Gene3D G3DSA:1.10.287.950 249 548 2.3E-54 T 11-10-2018 AFK25_03330 d22dcb103d20a60935e3b36cffe8d13d 550 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 400 429 8.2E-19 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_03330 d22dcb103d20a60935e3b36cffe8d13d 550 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 14 39 8.2E-19 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_03330 d22dcb103d20a60935e3b36cffe8d13d 550 PRINTS PR00260 Bacterial chemotaxis sensory transducer signature 371 398 8.2E-19 T 11-10-2018 IPR004090 Chemotaxis methyl-accepting receptor GO:0004888|GO:0006935|GO:0007165|GO:0016020 AFK25_03330 d22dcb103d20a60935e3b36cffe8d13d 550 SMART SM00304 191 244 1.4E-7 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_03330 d22dcb103d20a60935e3b36cffe8d13d 550 SMART SM00283 273 548 6.9E-43 T 11-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AFK25_03330 d22dcb103d20a60935e3b36cffe8d13d 550 Pfam PF00672 HAMP domain 193 240 5.8E-11 T 11-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AFK25_03330 d22dcb103d20a60935e3b36cffe8d13d 550 Gene3D G3DSA:1.20.1480.50 152 248 4.2E-12 T 11-10-2018 AFK25_03330 d22dcb103d20a60935e3b36cffe8d13d 550 SUPERFAMILY SSF58104 217 547 2.22E-60 T 11-10-2018 AFK25_13640 39d0f8b6cf6843d79d10a4b740ed8214 502 Pfam PF02028 BCCT, betaine/carnitine/choline family transporter 7 495 1.2E-196 T 11-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 AFK25_13640 39d0f8b6cf6843d79d10a4b740ed8214 502 TIGRFAM TIGR00842 bcct: transporter, betaine/carnitine/choline transporter (BCCT) family 50 496 3.7E-167 T 11-10-2018 IPR000060 BCCT transporter family GO:0016020|GO:0022857|GO:0071705 AFK25_01670 528de24794757cffb003c1b17ef06f6f 149 SUPERFAMILY SSF54001 28 149 2.16E-46 T 11-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AFK25_01670 528de24794757cffb003c1b17ef06f6f 149 Pfam PF00877 NlpC/P60 family 43 148 3.2E-35 T 11-10-2018 IPR000064 Endopeptidase, NLPC/P60 domain AFK25_01670 528de24794757cffb003c1b17ef06f6f 149 Gene3D G3DSA:3.90.1720.10 29 149 8.5E-48 T 11-10-2018 AFK25_03830 1f62941898a977394c2b67f23ded3825 289 Pfam PF17236 Family of unknown function (DUF5309) 14 286 2.6E-84 T 11-10-2018 IPR035198 Protein of unknown function DUF5309 AFK25_11495 e3ce4aed18989a013f72b8fffc2b29f4 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 70 278 1.5E-17 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_11495 e3ce4aed18989a013f72b8fffc2b29f4 288 SUPERFAMILY SSF161098 52 279 2.62E-68 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_11495 e3ce4aed18989a013f72b8fffc2b29f4 288 Gene3D G3DSA:1.10.3720.10 48 286 6.6E-76 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_11495 e3ce4aed18989a013f72b8fffc2b29f4 288 SUPERFAMILY SSF160964 6 39 8.24E-6 T 11-10-2018 AFK25_07935 949007c9141a553a298224a99af93ff4 81 Pfam PF07293 Protein of unknown function (DUF1450) 4 71 2.5E-13 T 11-10-2018 IPR009910 Protein of unknown function DUF1450 AFK25_07935 949007c9141a553a298224a99af93ff4 81 ProDom PD058324 UPF0349 LMO2392 BLI03401/BL03152 SA0800 SAR0901 LIN2491 SERP0525 GK2958 BT9727_4649 BC4937 4 67 3.0E-4 T 11-10-2018 AFK25_12970 e830aa28ff0ef84fa1ce66fb09ce7952 315 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 7 305 1.3E-123 T 11-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 AFK25_12970 e830aa28ff0ef84fa1ce66fb09ce7952 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 195 211 4.1E-73 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_12970 e830aa28ff0ef84fa1ce66fb09ce7952 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 8 30 4.1E-73 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_12970 e830aa28ff0ef84fa1ce66fb09ce7952 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 143 167 4.1E-73 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_12970 e830aa28ff0ef84fa1ce66fb09ce7952 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 234 255 4.1E-73 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_12970 e830aa28ff0ef84fa1ce66fb09ce7952 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 41 56 4.1E-73 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_12970 e830aa28ff0ef84fa1ce66fb09ce7952 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 61 71 4.1E-73 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_12970 e830aa28ff0ef84fa1ce66fb09ce7952 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 268 286 4.1E-73 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_12970 e830aa28ff0ef84fa1ce66fb09ce7952 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 106 114 4.1E-73 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_12970 e830aa28ff0ef84fa1ce66fb09ce7952 315 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 128 140 4.1E-73 T 11-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AFK25_12970 e830aa28ff0ef84fa1ce66fb09ce7952 315 Gene3D G3DSA:3.50.50.60 8 301 2.3E-121 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_12970 e830aa28ff0ef84fa1ce66fb09ce7952 315 ProSitePatterns PS00573 Pyridine nucleotide-disulphide oxidoreductases class-II active site. 135 155 - T 11-10-2018 IPR008255 Pyridine nucleotide-disulphide oxidoreductase, class-II, active site GO:0016491|GO:0055114 AFK25_12970 e830aa28ff0ef84fa1ce66fb09ce7952 315 SUPERFAMILY SSF51905 4 302 2.65E-60 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_12970 e830aa28ff0ef84fa1ce66fb09ce7952 315 Gene3D G3DSA:3.50.50.60 117 240 2.3E-121 T 11-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AFK25_12970 e830aa28ff0ef84fa1ce66fb09ce7952 315 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 7 294 3.9E-55 T 11-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AFK25_12970 e830aa28ff0ef84fa1ce66fb09ce7952 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 9 28 1.1E-39 T 11-10-2018 AFK25_12970 e830aa28ff0ef84fa1ce66fb09ce7952 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 147 165 1.1E-39 T 11-10-2018 AFK25_12970 e830aa28ff0ef84fa1ce66fb09ce7952 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 1.1E-39 T 11-10-2018 AFK25_12970 e830aa28ff0ef84fa1ce66fb09ce7952 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 105 123 1.1E-39 T 11-10-2018 AFK25_12970 e830aa28ff0ef84fa1ce66fb09ce7952 315 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 232 248 1.1E-39 T 11-10-2018 AFK25_05475 31fa2f17798e12cac0749e20a0606a8f 120 Pfam PF03780 Asp23 family, cell envelope-related function 9 116 6.2E-37 T 11-10-2018 IPR005531 Alkaline shock protein Asp23 AFK25_14145 f9d04d6c0bb2a12bcadf3bdc1e4157b3 78 Pfam PF17261 Family of unknown function (DUF5327) 2 78 1.2E-15 T 11-10-2018 IPR035218 Protein of unknown function DUF5327 AFK25_14145 f9d04d6c0bb2a12bcadf3bdc1e4157b3 78 ProDom PD705231 YWDI GROUP-SPECIFIC 1 49 4.0E-6 T 11-10-2018 IPR035218 Protein of unknown function DUF5327 AFK25_13815 2f9507d450e695001ed4de373b27159e 333 Gene3D G3DSA:3.30.460.80 156 310 1.3E-37 T 11-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13815 2f9507d450e695001ed4de373b27159e 333 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 212 327 9.1E-39 T 11-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13815 2f9507d450e695001ed4de373b27159e 333 SUPERFAMILY SSF143243 184 330 1.83E-41 T 11-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13815 2f9507d450e695001ed4de373b27159e 333 TIGRFAM TIGR01961 NuoC_fam: NADH (or F420H2) dehydrogenase, subunit C 213 327 2.3E-36 T 11-10-2018 IPR010218 NADH dehydrogenase, subunit C GO:0016651|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13815 2f9507d450e695001ed4de373b27159e 333 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 264 311 4.0E-19 T 11-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_03190 3f88cf8c016956d5a39e3f36a48f7cc6 427 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 209 415 5.1E-25 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_03190 3f88cf8c016956d5a39e3f36a48f7cc6 427 SUPERFAMILY SSF161098 174 409 4.71E-56 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_03190 3f88cf8c016956d5a39e3f36a48f7cc6 427 SUPERFAMILY SSF160964 68 179 6.54E-11 T 11-10-2018 AFK25_03190 3f88cf8c016956d5a39e3f36a48f7cc6 427 Gene3D G3DSA:1.10.3720.10 170 427 4.1E-69 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_08160 bdca8bf46bfcead20bc8a6c9d485a58f 350 Pfam PF01032 FecCD transport family 33 346 3.7E-96 T 11-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AFK25_08160 bdca8bf46bfcead20bc8a6c9d485a58f 350 Gene3D G3DSA:1.10.3470.10 18 350 2.9E-98 T 11-10-2018 IPR037294 ABC transporter, BtuC-like AFK25_08160 bdca8bf46bfcead20bc8a6c9d485a58f 350 SUPERFAMILY SSF81345 15 346 4.58E-86 T 11-10-2018 IPR037294 ABC transporter, BtuC-like AFK25_06635 0bacaf8adca9a459b63d10468c5c707e 329 Pfam PF05982 Na+-dependent bicarbonate transporter superfamily 12 326 9.0E-108 T 11-10-2018 IPR010293 Na+-dependent bicarbonate transporter superfamily AFK25_03505 4d5f66b08aa10647be1b06867f685778 394 Pfam PF06054 Competence protein CoiA-like family 1 386 8.2E-57 T 11-10-2018 IPR010330 Competence-induced protein CoiA-like AFK25_03505 4d5f66b08aa10647be1b06867f685778 394 PIRSF PIRSF007487 1 381 3.5E-79 T 11-10-2018 IPR021176 Competence-induced protein CoiA AFK25_04720 26d0f82e63ab06d38588e64add0ba7e9 346 Gene3D G3DSA:1.25.10.10 179 345 3.5E-12 T 11-10-2018 IPR011989 Armadillo-like helical AFK25_04720 26d0f82e63ab06d38588e64add0ba7e9 346 SUPERFAMILY SSF48371 171 322 5.76E-12 T 11-10-2018 IPR016024 Armadillo-type fold AFK25_13825 4470fbf7ac5f8f12f63e77f5991c6c3d 132 Hamap MF_01394 NAD(P)H-quinone oxidoreductase subunit 3, chloroplastic [ndhC]. 15 132 19.551 T 11-10-2018 IPR023043 NAD(P)H-quinone oxidoreductase subunit 3, bacterial/plastid GO:0016651|GO:0055114 AFK25_13825 4470fbf7ac5f8f12f63e77f5991c6c3d 132 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 34 131 2.9E-38 T 11-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_13825 4470fbf7ac5f8f12f63e77f5991c6c3d 132 Gene3D G3DSA:1.20.58.1610 9 132 9.5E-44 T 11-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AFK25_06310 c80fad3f9dd9ddda47505187d00f6157 150 Pfam PF03703 Bacterial PH domain 63 139 1.9E-19 T 11-10-2018 IPR005182 Domain of unknown function DUF304 AFK25_11405 c98efe4e607090b590910da88f648275 208 Pfam PF04854 Protein of unknown function, DUF624 22 98 6.4E-26 T 11-10-2018 IPR006938 Protein of unknown function DUF624 AFK25_09905 57ec8bf4070501d5507f7d82e0751f79 90 Pfam PF10942 Protein of unknown function (DUF2619) 14 82 1.3E-27 T 11-10-2018 IPR020390 Uncharacterised protein family YqhV AFK25_09905 57ec8bf4070501d5507f7d82e0751f79 90 ProDom PD064940 YQHV TRANSMEMBRANE MEMBRANE BH2798 7 86 1.0E-16 T 11-10-2018 IPR020390 Uncharacterised protein family YqhV AFK25_13745 be4c9e8aa081b0fc2a5e952b51dc7c6c 87 ProSitePatterns PS00894 DeoR-type HTH domain signature. 8 41 - T 11-10-2018 IPR018356 Transcription regulator, HTH DeoR-type, conserved site GO:0003700|GO:0006355 AFK25_13745 be4c9e8aa081b0fc2a5e952b51dc7c6c 87 Pfam PF12116 Stage III sporulation protein D 2 82 2.2E-41 T 11-10-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID AFK25_13745 be4c9e8aa081b0fc2a5e952b51dc7c6c 87 Gene3D G3DSA:1.10.10.60 1 87 3.6E-42 T 11-10-2018 AFK25_13745 be4c9e8aa081b0fc2a5e952b51dc7c6c 87 TIGRFAM TIGR02844 spore_III_D: sporulation transcriptional regulator SpoIIID 2 81 2.0E-45 T 11-10-2018 IPR014208 Sporulation stage III, transcriptional regulator SpoIIID AFK25_09385 e7dbb4ff74147ed856fa50aae4bf2682 335 SUPERFAMILY SSF53901 56 315 2.3E-14 T 11-10-2018 IPR016039 Thiolase-like GO:0003824 AFK25_09385 e7dbb4ff74147ed856fa50aae4bf2682 335 Pfam PF07451 Stage V sporulation protein AD (SpoVAD) 5 332 5.6E-138 T 11-10-2018 IPR010894 Stage V sporulation AD AFK25_09385 e7dbb4ff74147ed856fa50aae4bf2682 335 Gene3D G3DSA:3.40.47.40 1 335 4.8E-145 T 11-10-2018 IPR038369 Stage V sporulation AD superfamily AFK25_09385 e7dbb4ff74147ed856fa50aae4bf2682 335 PIRSF PIRSF011570 1 335 5.0E-149 T 11-10-2018 IPR010894 Stage V sporulation AD AFK25_09385 e7dbb4ff74147ed856fa50aae4bf2682 335 TIGRFAM TIGR02845 spore_V_AD: stage V sporulation protein AD 7 332 2.9E-144 T 11-10-2018 IPR010894 Stage V sporulation AD AFK25_04960 486c1cf3c224b2acb2bd953fb314924e 287 TIGRFAM TIGR01784 T_den_put_tspse: conserved hypothetical protein 5 283 1.3E-20 T 11-10-2018 IPR010106 Recombination-promoting nuclease RpnA AFK25_04960 486c1cf3c224b2acb2bd953fb314924e 287 Pfam PF04754 Putative transposase, YhgA-like 4 102 2.9E-5 T 11-10-2018 IPR006842 Transposase (putative), YhgA-like AFK25_02585 22705cfe6e3d238c48572c928adfdf7a 228 Pfam PF04298 Putative neutral zinc metallopeptidase 8 221 4.2E-87 T 11-10-2018 IPR007395 Putative neutral zinc metallopeptidase AFK25_06950 5ca69eab3c513874975e91f27f809add 227 Hamap MF_02088 Probable queuosine precursor transporter. 26 225 17.605 T 11-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 AFK25_06950 5ca69eab3c513874975e91f27f809add 227 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 27 223 3.4E-72 T 11-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 AFK25_06950 5ca69eab3c513874975e91f27f809add 227 Pfam PF02592 Putative vitamin uptake transporter 57 217 1.6E-54 T 11-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 AFK25_00945 1e751fe72fe0bb9ab54adee30ac6c899 206 Pfam PF04012 PspA/IM30 family 2 197 4.2E-18 T 11-10-2018 IPR007157 PspA/IM30 AFK25_00330 d88eab2b40042bb2d17edd134236844a 123 Pfam PF04977 Septum formation initiator 51 122 7.9E-18 T 11-10-2018 IPR007060 Septum formation initiator FtsL/DivIC AFK25_09530 77508ad9874e0a60d626986126539e71 165 Gene3D G3DSA:3.40.50.300 2 159 9.5E-48 T 11-10-2018 AFK25_09530 77508ad9874e0a60d626986126539e71 165 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 3 124 1.8E-33 T 11-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 AFK25_09530 77508ad9874e0a60d626986126539e71 165 SUPERFAMILY SSF52540 1 118 6.49E-16 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_09530 77508ad9874e0a60d626986126539e71 165 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 3 127 5.6E-32 T 11-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 AFK25_06255 6b53b716446ec7b161b1287d83bbce5d 211 PIRSF PIRSF006324 1 207 2.5E-57 T 11-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFK25_06255 6b53b716446ec7b161b1287d83bbce5d 211 Pfam PF01810 LysE type translocator 14 202 1.4E-33 T 11-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AFK25_09470 8313f9cbe9f1b9e85860d44578537e2c 66 Pfam PF13025 Protein of unknown function (DUF3886) 2 64 1.3E-22 T 11-10-2018 IPR024980 Protein of unknown function DUF3886 AFK25_06890 355109b92172a87e4ed2fc9782eeb600 70 ProDom PD048972 UPF0154 TRANSMEMBRANE MEMBRANE UNCHARACTERIZED FAMILY YNEF SUPERFAMILY MG335.1 EXPORTED MYCGA5700 24 60 2.0E-5 T 11-10-2018 IPR005359 Protein with unknown function UPF0154 AFK25_06890 355109b92172a87e4ed2fc9782eeb600 70 Pfam PF03672 Uncharacterised protein family (UPF0154) 9 67 5.7E-29 T 11-10-2018 IPR005359 Protein with unknown function UPF0154 AFK25_06375 ef2489865715726edb6b4cf7069b0b81 208 Pfam PF13630 SdpI/YhfL protein family 133 193 3.7E-21 T 11-10-2018 IPR025962 SdpI/YhfL protein family AFK25_06375 ef2489865715726edb6b4cf7069b0b81 208 Pfam PF07853 Protein of unknown function (DUF1648) 9 56 1.2E-16 T 11-10-2018 IPR012867 Domain of unknown function DUF1648 AFK25_06375 ef2489865715726edb6b4cf7069b0b81 208 PIRSF PIRSF038959 1 208 1.6E-49 T 11-10-2018 IPR026272 Immunity protein SdpI AFK25_08690 326b311cb07204510961439c456b6baf 70 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 1 57 3.0E-5 T 11-10-2018 AFK25_08690 326b311cb07204510961439c456b6baf 70 Pfam PF14178 YppF-like protein 1 59 1.5E-28 T 11-10-2018 IPR025553 YppF-like protein AFK25_11990 ff9e8dbb7074b82b8c1f1ff4968da759 223 Pfam PF04172 LrgB-like family 10 221 2.4E-71 T 11-10-2018 IPR007300 CidB/LrgB family AFK25_07825 22465c1ef6517f0d1d6b2d89db7ebc4b 149 SUPERFAMILY SSF160387 47 145 6.02E-22 T 11-10-2018 AFK25_07825 22465c1ef6517f0d1d6b2d89db7ebc4b 149 Pfam PF05573 NosL 12 142 6.5E-17 T 11-10-2018 IPR008719 Nitrous oxide reductase accessory protein NosL AFK25_13160 24425661b3e3f646185799161882e090 123 Gene3D G3DSA:3.30.160.170 23 119 2.1E-27 T 11-10-2018 IPR035924 FlaG-like superfamily AFK25_13160 24425661b3e3f646185799161882e090 123 SUPERFAMILY SSF160214 25 123 6.28E-26 T 11-10-2018 IPR035924 FlaG-like superfamily AFK25_13160 24425661b3e3f646185799161882e090 123 Pfam PF03646 FlaG protein 29 121 3.0E-23 T 11-10-2018 IPR005186 FlaG protein AFK25_13595 149309ca593e5ae164e938a80b5d5912 244 TIGRFAM TIGR00696 wecG_tagA_cpsF: glycosyltransferase, WecB/TagA/CpsF family 58 232 7.0E-55 T 11-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 AFK25_13595 149309ca593e5ae164e938a80b5d5912 244 Pfam PF03808 Glycosyl transferase WecB/TagA/CpsF family 61 226 3.6E-59 T 11-10-2018 IPR004629 Glycosyl transferase WecB/TagA/CpsF GO:0009058 AFK25_13595 149309ca593e5ae164e938a80b5d5912 244 Hamap MF_02070 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase. 4 241 60.895 T 11-10-2018 IPR034714 N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase GO:0047244 MetaCyc: PWY-7815|MetaCyc: PWY-7816|MetaCyc: PWY-7819 AFK25_11975 2b609f5e7a9592627ef6c2d0d16aa190 705 SUPERFAMILY SSF81296 102 203 3.5E-22 T 11-10-2018 IPR014756 Immunoglobulin E-set AFK25_11975 2b609f5e7a9592627ef6c2d0d16aa190 705 SUPERFAMILY SSF51445 206 618 1.1E-127 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily AFK25_11975 2b609f5e7a9592627ef6c2d0d16aa190 705 SMART SM00642 223 611 9.0E-8 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFK25_11975 2b609f5e7a9592627ef6c2d0d16aa190 705 TIGRFAM TIGR02104 pulA_typeI: pullulanase, type I 97 684 1.2E-248 T 11-10-2018 IPR011840 Pullulanase, type I AFK25_11975 2b609f5e7a9592627ef6c2d0d16aa190 705 Gene3D G3DSA:2.60.40.1180 621 705 1.3E-35 T 11-10-2018 IPR013780 Glycosyl hydrolase, all-beta AFK25_11975 2b609f5e7a9592627ef6c2d0d16aa190 705 Pfam PF00128 Alpha amylase, catalytic domain 378 572 4.4E-9 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFK25_11975 2b609f5e7a9592627ef6c2d0d16aa190 705 Pfam PF00128 Alpha amylase, catalytic domain 261 345 1.2E-5 T 11-10-2018 IPR006047 Glycosyl hydrolase, family 13, catalytic domain GO:0003824|GO:0005975 AFK25_11975 2b609f5e7a9592627ef6c2d0d16aa190 705 Gene3D G3DSA:2.60.40.2320 1 98 3.5E-38 T 11-10-2018 AFK25_11975 2b609f5e7a9592627ef6c2d0d16aa190 705 Gene3D G3DSA:2.60.40.10 99 203 1.8E-29 T 11-10-2018 IPR013783 Immunoglobulin-like fold AFK25_11975 2b609f5e7a9592627ef6c2d0d16aa190 705 Pfam PF02922 Carbohydrate-binding module 48 (Isoamylase N-terminal domain) 108 185 2.0E-15 T 11-10-2018 IPR004193 Glycoside hydrolase, family 13, N-terminal GO:0004553|GO:0005975 Reactome: R-HSA-3322077|Reactome: R-HSA-3878781 AFK25_11975 2b609f5e7a9592627ef6c2d0d16aa190 705 Gene3D G3DSA:3.20.20.80 204 620 1.2E-196 T 11-10-2018 AFK25_08605 bc4d531a74e7d09b5c3487c712a55e51 335 Pfam PF01032 FecCD transport family 20 333 3.0E-86 T 11-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AFK25_08605 bc4d531a74e7d09b5c3487c712a55e51 335 SUPERFAMILY SSF81345 4 333 8.24E-77 T 11-10-2018 IPR037294 ABC transporter, BtuC-like AFK25_08605 bc4d531a74e7d09b5c3487c712a55e51 335 Gene3D G3DSA:1.10.3470.10 5 335 8.2E-91 T 11-10-2018 IPR037294 ABC transporter, BtuC-like AFK25_04610 7307f989f9b3bf245baf1abcbd845d0b 158 Pfam PF01899 Na+/H+ ion antiporter subunit 9 156 3.6E-43 T 11-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 AFK25_04610 7307f989f9b3bf245baf1abcbd845d0b 158 PIRSF PIRSF019239 1 158 6.7E-46 T 11-10-2018 IPR002758 Na+/H+ antiporter subunit E GO:0006812|GO:0008324|GO:0016021 AFK25_14025 e397477b4c7dc6b94526441064a8bf76 712 Pfam PF13183 4Fe-4S dicluster domain 290 396 2.8E-12 T 11-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AFK25_14025 e397477b4c7dc6b94526441064a8bf76 712 SUPERFAMILY SSF103501 24 255 1.01E-14 T 11-10-2018 IPR036197 NarG-like superfamily AFK25_14025 e397477b4c7dc6b94526441064a8bf76 712 SUPERFAMILY SSF46548 273 412 2.79E-19 T 11-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AFK25_14025 e397477b4c7dc6b94526441064a8bf76 712 Pfam PF02754 Cysteine-rich domain 594 681 1.9E-18 T 11-10-2018 IPR004017 Cysteine-rich domain AFK25_14025 e397477b4c7dc6b94526441064a8bf76 712 Pfam PF02754 Cysteine-rich domain 479 555 2.0E-6 T 11-10-2018 IPR004017 Cysteine-rich domain AFK25_14025 e397477b4c7dc6b94526441064a8bf76 712 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 384 395 - T 11-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AFK25_09290 0502e76e2f1173aca9db5c42a2ab32cf 398 SUPERFAMILY SSF56059 141 320 8.84E-33 T 11-10-2018 AFK25_09290 0502e76e2f1173aca9db5c42a2ab32cf 398 Gene3D G3DSA:3.40.50.20 1 120 5.6E-10 T 11-10-2018 AFK25_09290 0502e76e2f1173aca9db5c42a2ab32cf 398 Pfam PF13535 ATP-grasp domain 142 280 4.5E-21 T 11-10-2018 AFK25_09290 0502e76e2f1173aca9db5c42a2ab32cf 398 Gene3D G3DSA:3.30.470.20 185 395 2.0E-51 T 11-10-2018 AFK25_14295 2f6cf297a827b23552c346b1603760cd 159 Gene3D G3DSA:3.90.960.10 1 159 4.8E-50 T 11-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 AFK25_14295 2f6cf297a827b23552c346b1603760cd 159 Pfam PF04073 Aminoacyl-tRNA editing domain 36 148 3.8E-23 T 11-10-2018 IPR007214 YbaK/aminoacyl-tRNA synthetase-associated domain GO:0002161 KEGG: 00970+6.1.1.15 AFK25_14295 2f6cf297a827b23552c346b1603760cd 159 TIGRFAM TIGR00011 YbaK_EbsC: Cys-tRNA(Pro) deacylase 6 156 2.9E-56 T 11-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC AFK25_14295 2f6cf297a827b23552c346b1603760cd 159 SUPERFAMILY SSF55826 6 156 1.44E-38 T 11-10-2018 IPR036754 YbaK/aminoacyl-tRNA synthetase-associated domain superfamily GO:0002161 KEGG: 00970+6.1.1.15 AFK25_14295 2f6cf297a827b23552c346b1603760cd 159 PIRSF PIRSF006181 1 159 2.9E-60 T 11-10-2018 IPR004369 Prolyl-tRNA editing protein, YbaK/EbsC AFK25_12210 e7710c9dac9136a44150da6e6eb945dd 345 Pfam PF02322 Cytochrome bd terminal oxidase subunit II 5 333 3.2E-36 T 11-10-2018 IPR003317 Cytochrome ubiquinol oxidase subunit 2 GO:0016020|GO:0055114 AFK25_06035 968a147db6464534fb498d5c7e1ab5ae 334 SMART SM00854 28 255 1.2E-86 T 11-10-2018 IPR019079 Capsule synthesis protein, CapA AFK25_06035 968a147db6464534fb498d5c7e1ab5ae 334 Pfam PF09587 Bacterial capsule synthesis protein PGA_cap 28 254 1.7E-57 T 11-10-2018 IPR019079 Capsule synthesis protein, CapA AFK25_06035 968a147db6464534fb498d5c7e1ab5ae 334 SUPERFAMILY SSF56300 28 272 3.07E-42 T 11-10-2018 AFK25_08025 dfbd6bb131c59a9ff4b6702d62fe09c9 186 SUPERFAMILY SSF53254 2 163 6.85E-16 T 11-10-2018 IPR029033 Histidine phosphatase superfamily AFK25_08025 dfbd6bb131c59a9ff4b6702d62fe09c9 186 Gene3D G3DSA:3.40.50.1240 1 185 1.1E-8 T 11-10-2018 IPR029033 Histidine phosphatase superfamily AFK25_08025 dfbd6bb131c59a9ff4b6702d62fe09c9 186 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 159 4.6E-6 T 11-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AFK25_02800 35012811c269bc50275651dfdf31f286 55 Pfam PF14147 Sporulation protein YhaL 5 50 1.6E-18 T 11-10-2018 IPR025428 Sporulation protein YhaL AFK25_01045 565a352448afc5858652f8e713dcb1f5 193 Pfam PF09335 SNARE associated Golgi protein 32 157 7.0E-19 T 11-10-2018 IPR032816 SNARE associated Golgi protein AFK25_06575 d4fce59e1174b1f983e0514c6dbe4f1b 149 SUPERFAMILY SSF111064 7 149 2.22E-58 T 11-10-2018 IPR036482 Hut operon regulatory protein HutP superfamily AFK25_06575 d4fce59e1174b1f983e0514c6dbe4f1b 149 Gene3D G3DSA:3.40.1510.10 1 149 4.1E-69 T 11-10-2018 IPR036482 Hut operon regulatory protein HutP superfamily AFK25_06575 d4fce59e1174b1f983e0514c6dbe4f1b 149 Hamap MF_00779 Hut operon positive regulatory protein [hutP]. 1 149 39.79 T 11-10-2018 IPR023552 Hut operon regulatory protein HutP, bacillales AFK25_06575 d4fce59e1174b1f983e0514c6dbe4f1b 149 Pfam PF09021 HutP 9 147 4.6E-42 T 11-10-2018 IPR015111 Hut operon regulatory protein HutP AFK25_05735 0b6f68c3d731cd4cb323b1476fc2d9b6 208 Pfam PF04347 Flagellar biosynthesis protein, FliO 88 184 9.8E-11 T 11-10-2018 IPR022781 Flagellar biosynthesis protein, FliO GO:0016021|GO:0044781 AFK25_14100 22fa9525210832c905aa4dec467aca99 303 Pfam PF08843 Nucleotidyl transferase AbiEii toxin, Type IV TA system 37 265 1.0E-39 T 11-10-2018 IPR014942 Nucleotidyl transferase AbiEii toxin, Type IV TA system AFK25_04890 8b2859f2c2a3755a7bd9399aedaa4fac 99 Pfam PF11256 Protein of unknown function (DUF3055) 7 86 7.5E-36 T 11-10-2018 IPR021415 Protein of unknown function DUF3055 AFK25_14415 ee049cf5f2488fdc0d2156f9b155b9c9 489 Pfam PF03323 Bacillus/Clostridium GerA spore germination protein 19 473 7.8E-180 T 11-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 AFK25_14415 ee049cf5f2488fdc0d2156f9b155b9c9 489 PIRSF PIRSF005690 5 489 3.5E-181 T 11-10-2018 IPR004995 Bacillus/Clostridium Ger spore germination protein GO:0009847|GO:0016021 AFK25_01925 3026ee3e789a6b0e653e996867584f88 176 SUPERFAMILY SSF159234 3 168 3.4E-30 T 11-10-2018 IPR035930 FomD-like superfamily AFK25_01925 3026ee3e789a6b0e653e996867584f88 176 Gene3D G3DSA:2.40.380.10 22 170 2.8E-10 T 11-10-2018 IPR035930 FomD-like superfamily AFK25_01925 3026ee3e789a6b0e653e996867584f88 176 Pfam PF04167 Protein of unknown function (DUF402) 60 124 9.5E-19 T 11-10-2018 IPR007295 Domain of unknown function DUF402 AFK25_01925 3026ee3e789a6b0e653e996867584f88 176 Hamap MF_01568 UPF0374 protein . 1 175 47.81 T 11-10-2018 IPR016882 Uncharacterised protein family UPF0374 AFK25_01925 3026ee3e789a6b0e653e996867584f88 176 PIRSF PIRSF028345 1 176 2.1E-74 T 11-10-2018 IPR016882 Uncharacterised protein family UPF0374 AFK25_06515 083b885e20aaab36c647f3e8a2db4ea4 216 SUPERFAMILY SSF161098 14 207 3.92E-46 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_06515 083b885e20aaab36c647f3e8a2db4ea4 216 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 12 109 1.7E-29 T 11-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 AFK25_06515 083b885e20aaab36c647f3e8a2db4ea4 216 Gene3D G3DSA:1.10.3720.10 7 216 5.0E-55 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_06515 083b885e20aaab36c647f3e8a2db4ea4 216 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 34 212 1.3E-19 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_12685 7cee8a918d37dbc0dd2817e0c2f94297 323 SUPERFAMILY SSF51261 122 311 5.07E-34 T 11-10-2018 IPR011055 Duplicated hybrid motif AFK25_12685 7cee8a918d37dbc0dd2817e0c2f94297 323 Gene3D G3DSA:2.70.70.10 117 322 7.2E-58 T 11-10-2018 IPR011055 Duplicated hybrid motif AFK25_12685 7cee8a918d37dbc0dd2817e0c2f94297 323 Pfam PF01551 Peptidase family M23 200 298 1.4E-19 T 11-10-2018 IPR016047 Peptidase M23 AFK25_10340 a1cf33700d9f1689d65f2df47c6e2108 329 Hamap MF_01562 UPF0365 protein . 3 323 49.15 T 11-10-2018 IPR022853 Uncharacterised protein family YdfA-immunity AFK25_10340 a1cf33700d9f1689d65f2df47c6e2108 329 Pfam PF12127 SigmaW regulon antibacterial 9 319 1.8E-166 T 11-10-2018 IPR022853 Uncharacterised protein family YdfA-immunity AFK25_08755 2672528a06e889b23b37ab50e06d7616 162 SUPERFAMILY SSF54403 34 95 5.1E-12 T 11-10-2018 AFK25_08755 2672528a06e889b23b37ab50e06d7616 162 Gene3D G3DSA:3.10.450.40 95 155 2.2E-24 T 11-10-2018 AFK25_08755 2672528a06e889b23b37ab50e06d7616 162 Gene3D G3DSA:3.10.450.40 25 94 6.2E-14 T 11-10-2018 AFK25_08755 2672528a06e889b23b37ab50e06d7616 162 SUPERFAMILY SSF54403 95 155 1.31E-15 T 11-10-2018 AFK25_09035 943b65245b6a83139226bf23aeffa555 224 PIRSF PIRSF016933 1 220 7.0E-85 T 11-10-2018 IPR023596 Peptidase PrsW, archaeal/bacterial GO:0008233 AFK25_09035 943b65245b6a83139226bf23aeffa555 224 Pfam PF13367 Protease prsW family 28 200 6.8E-33 T 11-10-2018 IPR026898 Protease PrsW GO:0008233 AFK25_08670 4fbef49720fbe011a81436a865b37ff5 262 ProDom PD038378 ECSC YDBA CC1715 BH1193 ECSC-LIKE ESCC 9 243 2.0E-68 T 11-10-2018 AFK25_08670 4fbef49720fbe011a81436a865b37ff5 262 Pfam PF12787 EcsC protein family 9 248 3.3E-77 T 11-10-2018 IPR024787 EcsC protein AFK25_07680 434d0fbd13199da253e8a850aa94a4b7 1209 SUPERFAMILY SSF52540 604 891 4.94E-34 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_07680 434d0fbd13199da253e8a850aa94a4b7 1209 Pfam PF00350 Dynamin family 50 204 2.3E-25 T 11-10-2018 IPR022812 Dynamin superfamily AFK25_07680 434d0fbd13199da253e8a850aa94a4b7 1209 Pfam PF00350 Dynamin family 625 851 7.6E-42 T 11-10-2018 IPR022812 Dynamin superfamily AFK25_07680 434d0fbd13199da253e8a850aa94a4b7 1209 SUPERFAMILY SSF52540 33 288 5.28E-35 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_07680 434d0fbd13199da253e8a850aa94a4b7 1209 Gene3D G3DSA:3.40.50.300 50 287 7.6E-41 T 11-10-2018 AFK25_13215 7f7a9c114e432086238e1f9919f96672 583 Pfam PF01973 Protein of unknown function DUF115 170 343 6.1E-42 T 11-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like AFK25_10480 0d930c4db7243207d2f7ee18278e86de 97 SMART SM01103 2 85 4.3E-44 T 11-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 AFK25_10480 0d930c4db7243207d2f7ee18278e86de 97 Gene3D G3DSA:3.30.110.60 1 97 2.2E-38 T 11-10-2018 IPR035920 YhbY-like superfamily AFK25_10480 0d930c4db7243207d2f7ee18278e86de 97 TIGRFAM TIGR00253 RNA_bind_YhbY: putative RNA-binding protein, YhbY family 2 96 1.7E-42 T 11-10-2018 IPR017924 RNA-binding protein YhbY GO:0003723 AFK25_10480 0d930c4db7243207d2f7ee18278e86de 97 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 8 97 1.0E-34 T 11-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 AFK25_10480 0d930c4db7243207d2f7ee18278e86de 97 Pfam PF01985 CRS1 / YhbY (CRM) domain 2 85 7.9E-25 T 11-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 AFK25_10480 0d930c4db7243207d2f7ee18278e86de 97 SUPERFAMILY SSF75471 1 95 3.27E-32 T 11-10-2018 IPR035920 YhbY-like superfamily AFK25_13110 737b238b4fe6968bfd749e0bc601af8d 286 Pfam PF10035 Uncharacterized protein conserved in bacteria (DUF2179) 226 280 1.5E-22 T 11-10-2018 IPR019264 Domain of unknown function DUF2179 AFK25_13110 737b238b4fe6968bfd749e0bc601af8d 286 Gene3D G3DSA:3.30.70.120 199 273 1.9E-27 T 11-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AFK25_13110 737b238b4fe6968bfd749e0bc601af8d 286 PIRSF PIRSF006483 1 286 1.1E-94 T 11-10-2018 IPR003740 Uncharacterised membrane protein YitT AFK25_13110 737b238b4fe6968bfd749e0bc601af8d 286 Pfam PF02588 Uncharacterised 5xTM membrane BCR, YitT family COG1284 17 220 3.7E-71 T 11-10-2018 IPR003740 Uncharacterised membrane protein YitT AFK25_04145 1d10b9328a611f04623597095617d3c3 102 SUPERFAMILY SSF89447 25 94 2.75E-16 T 11-10-2018 IPR037914 SpoVT-AbrB domain superfamily AFK25_04145 1d10b9328a611f04623597095617d3c3 102 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 26 71 5.4E-13 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFK25_04145 1d10b9328a611f04623597095617d3c3 102 SMART SM00966 26 73 1.6E-11 T 11-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AFK25_04145 1d10b9328a611f04623597095617d3c3 102 Gene3D G3DSA:2.10.260.10 17 101 1.3E-26 T 11-10-2018 AFK25_12850 ee61815faf712b4ee3a5feed8ba1cd3d 344 SUPERFAMILY SSF81345 12 336 2.22E-84 T 11-10-2018 IPR037294 ABC transporter, BtuC-like AFK25_12850 ee61815faf712b4ee3a5feed8ba1cd3d 344 Gene3D G3DSA:1.10.3470.10 16 341 2.2E-100 T 11-10-2018 IPR037294 ABC transporter, BtuC-like AFK25_12850 ee61815faf712b4ee3a5feed8ba1cd3d 344 Pfam PF01032 FecCD transport family 30 336 3.7E-97 T 11-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AFK25_08065 f18bb6c046a70b6ec4f25146eeca83fd 450 Pfam PF07670 Nucleoside recognition 138 231 6.3E-8 T 11-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 AFK25_11775 d6b9a1de0d0975e875de3f2ff650800a 355 Pfam PF02653 Branched-chain amino acid transport system / permease component 51 328 2.8E-38 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFK25_05815 9200f94d389ebabf1cae6b462eb3d1d7 151 ProDom PD177368 TRANSCRIPTION DNA-BINDING MOTILITY SWRB SWARMING YLXL REGULATION BH2428 1 151 2.0E-18 T 11-10-2018 AFK25_04895 68e0e17aed41ed6be2cd9a764f7080fa 37 Pfam PF13790 SR1 protein 1 37 1.5E-22 T 11-10-2018 IPR025236 SR1 protein AFK25_09185 03e418594f710db0dbcdd1b2bcd99714 183 SUPERFAMILY SSF52540 2 175 2.45E-37 T 11-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AFK25_09185 03e418594f710db0dbcdd1b2bcd99714 183 Gene3D G3DSA:3.40.50.300 2 175 1.2E-45 T 11-10-2018 AFK25_09185 03e418594f710db0dbcdd1b2bcd99714 183 Pfam PF02283 Cobinamide kinase / cobinamide phosphate guanyltransferase 3 172 9.4E-43 T 11-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 AFK25_09185 03e418594f710db0dbcdd1b2bcd99714 183 PIRSF PIRSF006135 1 177 2.2E-45 T 11-10-2018 IPR003203 Cobinamide kinase/cobinamide phosphate guanyltransferase GO:0000166|GO:0009236|GO:0043752|GO:0051188 KEGG: 00860+2.7.7.62+2.7.1.156|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 AFK25_13760 2e05a019cae868e39e5ff81bde792b04 432 Gene3D G3DSA:3.65.10.10 20 231 3.0E-176 T 11-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AFK25_13760 2e05a019cae868e39e5ff81bde792b04 432 Hamap MF_00111 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [murA]. 1 417 45.83 T 11-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFK25_13760 2e05a019cae868e39e5ff81bde792b04 432 TIGRFAM TIGR01072 murA: UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2 416 2.2E-176 T 11-10-2018 IPR005750 UDP-N-acetylglucosamine 1-carboxyvinyltransferase GO:0008760|GO:0019277 KEGG: 00520+2.5.1.7|KEGG: 00550+2.5.1.7|MetaCyc: PWY-6386|MetaCyc: PWY-6387|MetaCyc: PWY-7953 AFK25_13760 2e05a019cae868e39e5ff81bde792b04 432 Gene3D G3DSA:3.65.10.10 6 415 3.0E-176 T 11-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AFK25_13760 2e05a019cae868e39e5ff81bde792b04 432 SUPERFAMILY SSF55205 2 418 3.27E-142 T 11-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 AFK25_13760 2e05a019cae868e39e5ff81bde792b04 432 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 6 407 2.6E-118 T 11-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 AFK25_05975 b76475818e4d0832d33998471b5252cf 74 Pfam PF14035 YlzJ-like protein 3 65 6.6E-22 T 11-10-2018 IPR025619 YlzJ-like protein AFK25_03125 6a78d3ba2e6587c9c84873b32ed512b5 173 ProDom PD106196 YISN IG BH1722 2 164 9.0E-33 T 11-10-2018 IPR024488 Protein of unknown function DUF2777 AFK25_03125 6a78d3ba2e6587c9c84873b32ed512b5 173 Pfam PF10949 Protein of unknown function (DUF2777) 2 167 2.5E-49 T 11-10-2018 IPR024488 Protein of unknown function DUF2777 AFK25_01755 7aa064ff02b7cb4a1feb0e262416f281 72 Pfam PF06569 Protein of unknown function (DUF1128) 7 70 7.8E-32 T 11-10-2018 IPR009507 Protein of unknown function UPF0435 AFK25_01755 7aa064ff02b7cb4a1feb0e262416f281 72 Hamap MF_00829 UPF0435 protein . 3 70 19.904 T 11-10-2018 IPR009507 Protein of unknown function UPF0435 AFK25_03695 a2aba60b434d68cdfdb6f7f203f3b24d 84 Pfam PF14069 Stage VI sporulation protein F 6 77 2.3E-27 T 11-10-2018 IPR025942 Stage VI sporulation protein F AFK25_14130 3b9bac9d299a7fbe0904f924783ca8dc 140 Gene3D G3DSA:1.10.10.2520 8 92 2.0E-10 T 11-10-2018 AFK25_14130 3b9bac9d299a7fbe0904f924783ca8dc 140 Pfam PF07486 Cell Wall Hydrolase 26 129 2.3E-19 T 11-10-2018 IPR011105 Cell wall hydrolase, SleB GO:0016787 AFK25_11980 9d56a0f7bff426ef6cc90320f31373d2 312 Gene3D G3DSA:3.20.20.450 68 311 1.4E-63 T 11-10-2018 IPR035919 EAL domain superfamily AFK25_11980 9d56a0f7bff426ef6cc90320f31373d2 312 SUPERFAMILY SSF141868 81 309 7.32E-64 T 11-10-2018 IPR035919 EAL domain superfamily AFK25_11980 9d56a0f7bff426ef6cc90320f31373d2 312 SMART SM00052 73 312 2.5E-33 T 11-10-2018 IPR001633 EAL domain AFK25_11980 9d56a0f7bff426ef6cc90320f31373d2 312 Pfam PF00563 EAL domain 84 307 1.3E-54 T 11-10-2018 IPR001633 EAL domain AFK25_03675 c09db7a67d9ac275b2ec9097559345e8 285 Pfam PF07870 Protein of unknown function (DUF1657) 237 282 2.8E-18 T 11-10-2018 IPR012452 Protein of unknown function DUF1657 AFK25_03675 c09db7a67d9ac275b2ec9097559345e8 285 Pfam PF04239 Protein of unknown function (DUF421) 89 204 2.6E-34 T 11-10-2018 IPR007353 Protein of unknown function DUF421 AFK25_03675 c09db7a67d9ac275b2ec9097559345e8 285 Gene3D G3DSA:3.30.240.20 170 229 2.1E-17 T 11-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily AFK25_03675 c09db7a67d9ac275b2ec9097559345e8 285 Gene3D G3DSA:3.30.240.20 81 154 3.5E-25 T 11-10-2018 IPR023090 UPF0702, alpha/beta domain superfamily AFK25_09285 d6581cba073c652bc852ffa53b4489a1 370 SUPERFAMILY SSF46785 264 362 1.84E-15 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_09285 d6581cba073c652bc852ffa53b4489a1 370 SMART SM00418 280 359 5.5E-7 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_09285 d6581cba073c652bc852ffa53b4489a1 370 Pfam PF01022 Bacterial regulatory protein, arsR family 290 333 1.6E-5 T 11-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AFK25_09285 d6581cba073c652bc852ffa53b4489a1 370 Gene3D G3DSA:1.10.10.10 255 363 3.3E-16 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_08020 9f329db01fff46331a3dba0a70596bc9 208 Pfam PF08308 PEGA domain 139 200 6.9E-6 T 11-10-2018 IPR013229 PEGA AFK25_06760 2225f5cd705bfb0493f72d235b1d5c5a 288 Pfam PF12367 Pyruvate ferredoxin oxidoreductase beta subunit C terminal 199 264 4.1E-22 T 11-10-2018 IPR032686 Pyruvate ferredoxin oxidoreductase beta subunit, C-terminal AFK25_06760 2225f5cd705bfb0493f72d235b1d5c5a 288 Gene3D G3DSA:3.40.50.970 71 209 1.5E-30 T 11-10-2018 AFK25_06760 2225f5cd705bfb0493f72d235b1d5c5a 288 TIGRFAM TIGR02177 PorB_KorB: 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate family 14 280 5.3E-96 T 11-10-2018 IPR011896 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate AFK25_06760 2225f5cd705bfb0493f72d235b1d5c5a 288 SUPERFAMILY SSF52518 12 286 6.91E-80 T 11-10-2018 IPR029061 Thiamin diphosphate-binding fold AFK25_06760 2225f5cd705bfb0493f72d235b1d5c5a 288 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 48 195 2.2E-33 T 11-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AFK25_10795 09a46ffe405ff312ec102603beff5b34 90 Pfam PF13797 Post-transcriptional regulator 3 81 8.5E-30 T 11-10-2018 IPR025716 Post-transcriptional regulator AFK25_01975 f530462647ad7770f5d2aaa922df1e14 263 Pfam PF06182 ABC-2 family transporter protein 31 262 8.6E-21 T 11-10-2018 IPR010390 Protein of unknown function DUF990 AFK25_13565 b404444a74bf20d37fc5749a58696f04 142 Pfam PF06935 Protein of unknown function (DUF1284) 19 125 6.4E-23 T 11-10-2018 IPR009702 Protein of unknown function DUF1284 AFK25_00930 e80de3837674e91bbeaf8af5f6eb8013 315 Pfam PF00892 EamA-like transporter family 5 146 2.2E-24 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFK25_00930 e80de3837674e91bbeaf8af5f6eb8013 315 Pfam PF00892 EamA-like transporter family 158 291 8.9E-23 T 11-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AFK25_00930 e80de3837674e91bbeaf8af5f6eb8013 315 SUPERFAMILY SSF103481 204 295 4.32E-13 T 11-10-2018 AFK25_00930 e80de3837674e91bbeaf8af5f6eb8013 315 SUPERFAMILY SSF103481 41 148 4.84E-10 T 11-10-2018 AFK25_09210 9e4079c19f29f1bc6348ad85e738f41d 318 Pfam PF01497 Periplasmic binding protein 63 292 9.7E-42 T 11-10-2018 IPR002491 ABC transporter periplasmic binding domain AFK25_09210 9e4079c19f29f1bc6348ad85e738f41d 318 SUPERFAMILY SSF53807 41 314 9.81E-74 T 11-10-2018 AFK25_09210 9e4079c19f29f1bc6348ad85e738f41d 318 Gene3D G3DSA:3.40.50.1980 23 179 3.0E-39 T 11-10-2018 AFK25_09210 9e4079c19f29f1bc6348ad85e738f41d 318 Gene3D G3DSA:3.40.50.1980 182 315 4.8E-45 T 11-10-2018 AFK25_11335 95943045d25cdfcab41ae17d8e4c25e2 135 Pfam PF03994 Domain of Unknown Function (DUF350) 80 134 3.7E-16 T 11-10-2018 IPR007140 Protein of unknown function DUF350 AFK25_11335 95943045d25cdfcab41ae17d8e4c25e2 135 Pfam PF03994 Domain of Unknown Function (DUF350) 18 68 5.9E-14 T 11-10-2018 IPR007140 Protein of unknown function DUF350 AFK25_09230 e47b62644b317c8e19d093f01402c868 538 Pfam PF05140 ResB-like family 440 519 3.8E-17 T 11-10-2018 IPR007816 ResB-like domain AFK25_09230 e47b62644b317c8e19d093f01402c868 538 Pfam PF05140 ResB-like family 62 429 1.8E-80 T 11-10-2018 IPR007816 ResB-like domain AFK25_08830 9d68321817cbc08b971352d4407b6a96 189 Pfam PF07187 Protein of unknown function (DUF1405) 24 182 1.3E-59 T 11-10-2018 IPR009845 Protein of unknown function DUF1405 AFK25_07365 bf48faf49e63af437105b6d0c2a00c01 288 Gene3D G3DSA:1.10.3720.10 6 278 3.8E-38 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_07365 bf48faf49e63af437105b6d0c2a00c01 288 SUPERFAMILY SSF161098 9 269 1.57E-32 T 11-10-2018 IPR035906 MetI-like superfamily AFK25_07365 bf48faf49e63af437105b6d0c2a00c01 288 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 74 270 1.2E-10 T 11-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AFK25_14140 f4bcfb3264df59d572bc42968591e70e 120 Pfam PF04241 Protein of unknown function (DUF423) 18 102 1.8E-30 T 11-10-2018 IPR006696 Protein of unknown function DUF423 AFK25_09785 f2dc877c47a44fce3924dfdf5821dbb9 84 Pfam PF11118 Protein of unknown function (DUF2627) 2 77 1.4E-37 T 11-10-2018 IPR020138 Uncharacterised protein family YqzF AFK25_09785 f2dc877c47a44fce3924dfdf5821dbb9 84 ProDom PD058321 YQZF GSC13 TRANSMEMBRANE IG GKC13 MEMBRANE PROTEINS BH2767 RBL05544 SIMILAR 1 77 6.0E-14 T 11-10-2018 IPR020138 Uncharacterised protein family YqzF AFK25_03250 5cdc162b48e420238e8d7638f72ded74 258 TIGRFAM TIGR00715 precor6x_red: precorrin-6x reductase 2 246 1.6E-56 T 11-10-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 AFK25_03250 5cdc162b48e420238e8d7638f72ded74 258 Pfam PF02571 Precorrin-6x reductase CbiJ/CobK 2 247 5.7E-74 T 11-10-2018 IPR003723 Precorrin-6x reductase GO:0009236|GO:0016994|GO:0055114 AFK25_09790 d205ca0d818e9dadfee11683b27fc8b2 244 Pfam PF03009 Glycerophosphoryl diester phosphodiesterase family 7 232 9.1E-52 T 11-10-2018 IPR030395 Glycerophosphodiester phosphodiesterase domain GO:0006629|GO:0008081 AFK25_09790 d205ca0d818e9dadfee11683b27fc8b2 244 Gene3D G3DSA:3.20.20.190 1 240 2.3E-83 T 11-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 AFK25_09790 d205ca0d818e9dadfee11683b27fc8b2 244 SUPERFAMILY SSF51695 2 237 6.54E-74 T 11-10-2018 IPR017946 PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily GO:0006629|GO:0008081 AFK25_01740 f51d7b01e861e35c983c98fa9defbbfd 342 Pfam PF01384 Phosphate transporter family 10 293 4.3E-44 T 11-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 AFK25_09150 756725a200162da53d556e284c47e46b 270 Gene3D G3DSA:3.20.20.140 2 269 2.9E-65 T 11-10-2018 AFK25_09150 756725a200162da53d556e284c47e46b 270 SUPERFAMILY SSF89550 1 263 3.01E-38 T 11-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AFK25_09150 756725a200162da53d556e284c47e46b 270 TIGRFAM TIGR01856 hisJ_fam: histidinol phosphate phosphatase, HisJ family 4 244 3.7E-37 T 11-10-2018 IPR010140 Histidinol phosphate phosphatase, HisJ GO:0000105|GO:0004401 KEGG: 00340+3.1.3.15 AFK25_06670 0a452c08549ae113bedeaf0dcf46f5f5 248 Hamap MF_01811 Membrane protein insertase YidC [yidC]. 1 240 29.543 T 11-10-2018 IPR023060 Membrane insertase YidC/YidC1/YidC2, Firmicutes GO:0016021|GO:0032977 AFK25_06670 0a452c08549ae113bedeaf0dcf46f5f5 248 Pfam PF02096 60Kd inner membrane protein 53 236 1.4E-57 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFK25_06670 0a452c08549ae113bedeaf0dcf46f5f5 248 TIGRFAM TIGR03592 yidC_oxa1_cterm: membrane protein insertase, YidC/Oxa1 family 52 236 1.5E-63 T 11-10-2018 IPR028055 Membrane insertase YidC/Oxa1, C-terminal Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_06670 0a452c08549ae113bedeaf0dcf46f5f5 248 PRINTS PR00701 60kDa inner membrane protein signature 118 141 1.5E-18 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFK25_06670 0a452c08549ae113bedeaf0dcf46f5f5 248 PRINTS PR00701 60kDa inner membrane protein signature 163 185 1.5E-18 T 11-10-2018 IPR001708 Membrane insertase YidC/ALB3/OXA1/COX18 GO:0016021|GO:0032977 AFK25_10600 d651c04d6e127d56c855f31514c4e86b 79 Pfam PF14143 YrhC-like protein 10 78 5.1E-24 T 11-10-2018 IPR025418 YrhC-like protein AFK25_10600 d651c04d6e127d56c855f31514c4e86b 79 ProDom PD057834 YRHC TRANSMEMBRANE MEMBRANE 16 77 1.0E-5 T 11-10-2018 IPR025418 YrhC-like protein AFK25_06545 8fe5cac8a1dda1e145f019b31ffe897c 655 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 62 217 1.7E-34 T 11-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like AFK25_07655 69872dba914b48db9d888b8cc5a3eea0 74 TIGRFAM TIGR03090 SASP_tlp: small, acid-soluble spore protein tlp 3 69 7.2E-27 T 11-10-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like AFK25_07655 69872dba914b48db9d888b8cc5a3eea0 74 Hamap MF_01506 Small, acid-soluble spore protein Tlp [tlp]. 1 74 31.327 T 11-10-2018 IPR017524 Small acid-soluble spore protein, thioredoxin-like AFK25_11235 3d113ee96fa07ab18d0632cd7da0abac 149 Gene3D G3DSA:3.10.129.10 4 149 3.4E-38 T 11-10-2018 AFK25_11235 3d113ee96fa07ab18d0632cd7da0abac 149 Pfam PF03061 Thioesterase superfamily 32 116 8.2E-15 T 11-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AFK25_11235 3d113ee96fa07ab18d0632cd7da0abac 149 SUPERFAMILY SSF54637 15 147 7.94E-36 T 11-10-2018 IPR029069 HotDog domain superfamily AFK25_09595 adf52cd1225b45db98c50bbbd790d413 231 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 83 103 4.8E-25 T 11-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFK25_09595 adf52cd1225b45db98c50bbbd790d413 231 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 104 124 4.8E-25 T 11-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFK25_09595 adf52cd1225b45db98c50bbbd790d413 231 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 28 45 4.8E-25 T 11-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFK25_09595 adf52cd1225b45db98c50bbbd790d413 231 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 139 165 4.8E-25 T 11-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFK25_09595 adf52cd1225b45db98c50bbbd790d413 231 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 45 65 4.8E-25 T 11-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFK25_09595 adf52cd1225b45db98c50bbbd790d413 231 Pfam PF01578 Cytochrome C assembly protein 4 168 2.6E-20 T 11-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 AFK25_09995 2a7c8e980673126bab539afd409057ac 62 Pfam PF14038 YqzE-like protein 3 59 3.3E-27 T 11-10-2018 IPR025622 YqzE-like protein AFK25_10880 05890911d2b532b52c9632820e80e35f 276 Gene3D G3DSA:3.90.1170.20 13 273 1.8E-107 T 11-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 AFK25_10880 05890911d2b532b52c9632820e80e35f 276 SUPERFAMILY SSF51690 109 275 8.24E-64 T 11-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 AFK25_10880 05890911d2b532b52c9632820e80e35f 276 PIRSF PIRSF006250 2 276 7.1E-101 T 11-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 AFK25_10880 05890911d2b532b52c9632820e80e35f 276 Gene3D G3DSA:3.20.20.70 123 265 1.8E-107 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_10880 05890911d2b532b52c9632820e80e35f 276 SUPERFAMILY SSF54675 4 108 3.53E-27 T 11-10-2018 AFK25_10880 05890911d2b532b52c9632820e80e35f 276 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 10 274 2.1E-105 T 11-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 AFK25_10880 05890911d2b532b52c9632820e80e35f 276 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 18 107 1.0E-24 T 11-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 AFK25_10880 05890911d2b532b52c9632820e80e35f 276 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 109 273 3.1E-67 T 11-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 AFK25_09075 6afd510ee2b512da6a37b85427c97266 195 PIRSF PIRSF029008 1 194 8.4E-56 T 11-10-2018 IPR008681 Negative regulator of genetic competence, MecA AFK25_09075 6afd510ee2b512da6a37b85427c97266 195 Gene3D G3DSA:3.30.70.1950 104 193 1.6E-27 T 11-10-2018 IPR038471 MecA, C-terminal domain superfamily AFK25_09075 6afd510ee2b512da6a37b85427c97266 195 Pfam PF05389 Negative regulator of genetic competence (MecA) 100 188 3.5E-13 T 11-10-2018 IPR008681 Negative regulator of genetic competence, MecA AFK25_09075 6afd510ee2b512da6a37b85427c97266 195 Pfam PF05389 Negative regulator of genetic competence (MecA) 1 88 2.3E-23 T 11-10-2018 IPR008681 Negative regulator of genetic competence, MecA AFK25_09075 6afd510ee2b512da6a37b85427c97266 195 Hamap MF_01124 Adapter protein MecA [mecA]. 1 192 23.379 T 11-10-2018 IPR008681 Negative regulator of genetic competence, MecA AFK25_02605 d7b850b6160e65f5f0427d398f70805e 154 Gene3D G3DSA:3.40.30.10 49 151 4.5E-20 T 11-10-2018 AFK25_02605 d7b850b6160e65f5f0427d398f70805e 154 Pfam PF00085 Thioredoxin 61 151 1.8E-12 T 11-10-2018 IPR013766 Thioredoxin domain GO:0045454 AFK25_02605 d7b850b6160e65f5f0427d398f70805e 154 SUPERFAMILY SSF52833 47 151 1.1E-24 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_09450 e019341ac47de7230b05b80fa3598a35 150 SUPERFAMILY SSF46785 6 140 1.06E-38 T 11-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AFK25_09450 e019341ac47de7230b05b80fa3598a35 150 Gene3D G3DSA:3.30.1490.190 93 150 2.5E-16 T 11-10-2018 AFK25_09450 e019341ac47de7230b05b80fa3598a35 150 Pfam PF01475 Ferric uptake regulator family 16 136 7.9E-40 T 11-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 AFK25_09450 e019341ac47de7230b05b80fa3598a35 150 Gene3D G3DSA:1.10.10.10 1 88 2.9E-29 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_02570 f64e21fae97591b5ec3ccc29d7d73acc 258 Pfam PF01925 Sulfite exporter TauE/SafE 9 252 5.2E-41 T 11-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFK25_12225 3dc383cb96e1d84d984eeb187635edf3 348 PIRSF PIRSF000355 4 348 8.4E-105 T 11-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_12225 3dc383cb96e1d84d984eeb187635edf3 348 Pfam PF00268 Ribonucleotide reductase, small chain 32 308 2.4E-70 T 11-10-2018 IPR000358 Ribonucleotide reductase small subunit family GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AFK25_12225 3dc383cb96e1d84d984eeb187635edf3 348 Gene3D G3DSA:1.10.620.20 24 318 2.3E-83 T 11-10-2018 IPR012348 Ribonucleotide reductase-like GO:0016491|GO:0055114 Reactome: R-HSA-499943 AFK25_12225 3dc383cb96e1d84d984eeb187635edf3 348 SUPERFAMILY SSF47240 22 348 1.57E-80 T 11-10-2018 IPR009078 Ferritin-like superfamily AFK25_13155 d9e0712a5912af59ce756bc5a1b22af6 524 Pfam PF07195 Flagellar hook-associated protein 2 C-terminus 240 509 5.3E-52 T 11-10-2018 IPR010809 Flagellar hook-associated protein 2, C-terminal GO:0007155|GO:0009288 AFK25_13155 d9e0712a5912af59ce756bc5a1b22af6 524 Pfam PF02465 Flagellar hook-associated protein 2 N-terminus 11 107 1.9E-23 T 11-10-2018 IPR003481 Flagellar hook-associated protein 2, N-terminal GO:0009424 AFK25_03650 5c2790f413c8c8d77963e4a57abcb43d 151 Pfam PF09580 Sporulation lipoprotein YhcN/YlaJ (Spore_YhcN_YlaJ) 30 132 2.6E-8 T 11-10-2018 IPR019076 Sporulation lipoprotein YhcN/YlaJ-like AFK25_05010 a8a0a2eb8d46f2cb6c40043500c0d9a6 298 Pfam PF02628 Cytochrome oxidase assembly protein 38 271 2.7E-33 T 11-10-2018 IPR003780 COX15/CtaA family GO:0006784|GO:0016021|GO:0016627|GO:0055114 Reactome: R-HSA-189451 AFK25_05010 a8a0a2eb8d46f2cb6c40043500c0d9a6 298 Hamap MF_01664 Heme A synthase [ctaA]. 1 286 29.081 T 11-10-2018 IPR023755 Heme A synthase, type 1 GO:0006784|GO:0016020|GO:0016627|GO:0055114 AFK25_07820 645e1455d047b9c3edadc589ea06000a 269 Pfam PF12679 ABC-2 family transporter protein 44 263 1.2E-8 T 11-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 AFK25_03755 7ca565194bbaf9aec784402d9f03e5f7 159 Pfam PF07883 Cupin domain 63 138 3.9E-16 T 11-10-2018 IPR013096 Cupin 2, conserved barrel AFK25_03755 7ca565194bbaf9aec784402d9f03e5f7 159 Gene3D G3DSA:2.60.120.10 38 159 3.0E-43 T 11-10-2018 IPR014710 RmlC-like jelly roll fold AFK25_03755 7ca565194bbaf9aec784402d9f03e5f7 159 SUPERFAMILY SSF51182 8 143 2.06E-27 T 11-10-2018 IPR011051 RmlC-like cupin domain superfamily AFK25_03900 7287419cc6924737b727e801a16a7e05 133 SUPERFAMILY SSF53927 2 130 1.74E-26 T 11-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 AFK25_03900 7287419cc6924737b727e801a16a7e05 133 Gene3D G3DSA:3.40.140.10 1 133 2.7E-30 T 11-10-2018 AFK25_08150 213862fc8810a53a4bcedfc581a74532 238 Pfam PF06276 Ferric iron reductase FhuF-like transporter 59 187 2.3E-11 T 11-10-2018 IPR022770 Ferric iron reductase FhuF domain AFK25_04130 6a8ee499b7b35fc48bd15fbc5c44d2fb 440 Pfam PF03600 Citrate transporter 20 255 5.6E-9 T 11-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 AFK25_06640 beb19ba671064a273a0a751945724437 119 Pfam PF10057 Uncharacterized conserved protein (DUF2294) 3 112 9.3E-43 T 11-10-2018 IPR018745 Domain of unknown function DUF2294 AFK25_04365 b0d861eb9a5dfa5a1bb2d96a5725b08d 319 Pfam PF02653 Branched-chain amino acid transport system / permease component 33 311 6.7E-50 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFK25_12205 e9b79254ea073b5294f2c51d66eca830 442 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 7 433 3.3E-124 T 11-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 AFK25_12205 e9b79254ea073b5294f2c51d66eca830 442 PIRSF PIRSF006446 1 442 5.0E-115 T 11-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 AFK25_01345 9580caad6b84a7970ce026e1888de754 87 Pfam PF11127 Protein of unknown function (DUF2892) 1 67 6.2E-14 T 11-10-2018 IPR021309 Protein of unknown function DUF2892 AFK25_07610 870e405c57766d59f4646df8f9dd2b03 105 Pfam PF14191 YodL-like 28 99 5.1E-6 T 11-10-2018 IPR025923 YodL-like AFK25_07610 870e405c57766d59f4646df8f9dd2b03 105 ProDom PD030115 YODL GK1575 15 104 7.0E-28 T 11-10-2018 AFK25_07795 9f158e0ece2d747213c2727ab4e44ad6 400 Pfam PF02796 Helix-turn-helix domain of resolvase 10 39 3.3E-6 T 11-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 AFK25_07795 9f158e0ece2d747213c2727ab4e44ad6 400 Gene3D G3DSA:3.30.420.10 113 287 3.0E-10 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFK25_07795 9f158e0ece2d747213c2727ab4e44ad6 400 SUPERFAMILY SSF53098 115 286 5.88E-22 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_07795 9f158e0ece2d747213c2727ab4e44ad6 400 Gene3D G3DSA:1.10.10.60 8 40 1.9E-7 T 11-10-2018 AFK25_07795 9f158e0ece2d747213c2727ab4e44ad6 400 Pfam PF00665 Integrase core domain 116 242 8.6E-27 T 11-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFK25_13685 9f158e0ece2d747213c2727ab4e44ad6 400 Pfam PF02796 Helix-turn-helix domain of resolvase 10 39 3.3E-6 T 11-10-2018 IPR006120 Resolvase, HTH domain GO:0000150|GO:0003677|GO:0006310 AFK25_13685 9f158e0ece2d747213c2727ab4e44ad6 400 Gene3D G3DSA:3.30.420.10 113 287 3.0E-10 T 11-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AFK25_13685 9f158e0ece2d747213c2727ab4e44ad6 400 SUPERFAMILY SSF53098 115 286 5.88E-22 T 11-10-2018 IPR012337 Ribonuclease H-like superfamily AFK25_13685 9f158e0ece2d747213c2727ab4e44ad6 400 Gene3D G3DSA:1.10.10.60 8 40 1.9E-7 T 11-10-2018 AFK25_13685 9f158e0ece2d747213c2727ab4e44ad6 400 Pfam PF00665 Integrase core domain 116 242 8.6E-27 T 11-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AFK25_09375 82120794c5c2006d8253f33226d653b0 200 Pfam PF14097 Stage V sporulation protein AE1 5 184 2.2E-81 T 11-10-2018 IPR025914 Stage V sporulation protein AE AFK25_06290 a9275b29f131df6aadaf2e2235ed394c 108 Pfam PF05610 Protein of unknown function (DUF779) 14 107 1.7E-50 T 11-10-2018 IPR008497 Protein of unknown function DUF779 AFK25_06290 a9275b29f131df6aadaf2e2235ed394c 108 PIRSF PIRSF009151 1 108 5.9E-58 T 11-10-2018 IPR008497 Protein of unknown function DUF779 AFK25_08165 83cef0e3382b1a8aeec5407259808593 332 Gene3D G3DSA:1.10.3470.10 3 330 9.8E-90 T 11-10-2018 IPR037294 ABC transporter, BtuC-like AFK25_08165 83cef0e3382b1a8aeec5407259808593 332 Pfam PF01032 FecCD transport family 19 328 5.4E-93 T 11-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AFK25_08165 83cef0e3382b1a8aeec5407259808593 332 SUPERFAMILY SSF81345 7 328 1.01E-79 T 11-10-2018 IPR037294 ABC transporter, BtuC-like AFK25_13725 fb1974e77cc0b61d87cc7cf73c924fc3 69 Pfam PF11772 DNA-directed RNA polymerase subunit beta 23 68 1.3E-21 T 11-10-2018 IPR024596 DNA-directed RNA polymerase subunit beta/EpuA AFK25_08410 8f7853bd112ddae82c9b702843b3069c 242 Pfam PF13386 Cytochrome C biogenesis protein transmembrane region 30 235 9.7E-23 T 11-10-2018 IPR039447 Urease accessory protein UreH-like, transmembrane domain AFK25_03645 89c8b28044be97f7e87607e50a5c7d3b 67 Pfam PF07870 Protein of unknown function (DUF1657) 7 55 1.7E-22 T 11-10-2018 IPR012452 Protein of unknown function DUF1657 AFK25_10015 fab93ecdd05e89c8d7fcb119e9bebc62 102 Pfam PF07963 Prokaryotic N-terminal methylation motif 2 19 1.6E-4 T 11-10-2018 IPR012902 Prokaryotic N-terminal methylation site AFK25_01700 6e614e364abff17964bbdaed6071cc29 48 Pfam PF12669 Virus attachment protein p12 family 4 45 1.6E-8 T 11-10-2018 AFK25_00170 d646a18cb9c4ea31f7bbe9934a933790 60 Pfam PF10764 Inhibitor of sigma-G Gin 7 51 4.3E-18 T 11-10-2018 IPR019700 Anti-sigma-G factor Gin AFK25_14360 a4c540964855bbdd68362d5df6fc45da 312 SUPERFAMILY SSF48576 28 307 1.44E-32 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFK25_14360 a4c540964855bbdd68362d5df6fc45da 312 Pfam PF00348 Polyprenyl synthetase 72 256 3.3E-15 T 11-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 AFK25_14360 a4c540964855bbdd68362d5df6fc45da 312 Gene3D G3DSA:1.10.600.10 26 312 1.2E-31 T 11-10-2018 IPR008949 Isoprenoid synthase domain superfamily AFK25_02450 c52e13f4e8636518c2146c6fcbe3c20a 72 Gene3D G3DSA:3.10.350.10 3 64 4.7E-5 T 11-10-2018 IPR036779 LysM domain superfamily AFK25_02450 c52e13f4e8636518c2146c6fcbe3c20a 72 Pfam PF05489 Phage Tail Protein X 5 57 2.2E-5 T 11-10-2018 IPR008861 Phage Tail Protein X-like AFK25_09110 fdf8e2d450b5a369784ffa1f89304180 145 Pfam PF10864 Protein of unknown function (DUF2663) 14 143 1.7E-39 T 11-10-2018 IPR020210 Uncharacterised protein family, YpbF, transmembrane AFK25_09110 fdf8e2d450b5a369784ffa1f89304180 145 ProDom PD089241 YPBF MEMBRANE BH1610 TRANSMEMBRANE 9 142 1.0E-15 T 11-10-2018 IPR020210 Uncharacterised protein family, YpbF, transmembrane AFK25_07645 b445ed066e4074959a94cbc79084fdb0 95 PIRSF PIRSF034852 1 95 6.4E-37 T 11-10-2018 IPR008326 Uncharacterised conserved protein UCP034852 AFK25_07645 b445ed066e4074959a94cbc79084fdb0 95 SUPERFAMILY SSF89360 1 93 2.55E-10 T 11-10-2018 IPR035903 HesB-like domain superfamily Reactome: R-HSA-1362409 AFK25_04985 8ca7f8c9b25d399c62279d327065b578 166 ProDom PD094668 YLAL SIMILAR MW0994 BH2628 SE0810 SA0960 4 165 1.0E-58 T 11-10-2018 IPR020229 Uncharacterised protein YlaL AFK25_06910 e2a913a46db3b337321d68556f8cebcf 145 Pfam PF11084 Protein of unknown function (DUF2621) 4 141 1.0E-73 T 11-10-2018 IPR020203 Uncharacterised protein family, YneK AFK25_06910 e2a913a46db3b337321d68556f8cebcf 145 ProDom PD086666 YNEK BH2332 21 145 5.0E-51 T 11-10-2018 IPR020203 Uncharacterised protein family, YneK AFK25_01980 1ad6fdb5c1d6a7ca3a34b6925b4bbf26 261 Pfam PF06182 ABC-2 family transporter protein 34 260 1.0E-52 T 11-10-2018 IPR010390 Protein of unknown function DUF990 AFK25_13050 d6ee960c6e3e00655a9e7976812a4cfb 65 Pfam PF04024 PspC domain 2 60 1.9E-16 T 11-10-2018 IPR007168 Phage shock protein, PspC, N-terminal AFK25_09225 d0808c97d75dc140d9adc3aae32cde1b 391 TIGRFAM TIGR03144 cytochr_II_ccsB: cytochrome c-type biogenesis protein CcsB 46 389 6.5E-77 T 11-10-2018 IPR017562 Cytochrome c-type biogenesis protein CcsA GO:0017004 AFK25_09225 d0808c97d75dc140d9adc3aae32cde1b 391 Pfam PF01578 Cytochrome C assembly protein 258 386 2.6E-24 T 11-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 AFK25_09225 d0808c97d75dc140d9adc3aae32cde1b 391 Pfam PF01578 Cytochrome C assembly protein 70 189 2.2E-8 T 11-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 AFK25_05135 9618fe3f8b8fa43c57fbd528d143d0ce 258 SUPERFAMILY SSF52151 1 252 1.99E-57 T 11-10-2018 IPR016035 Acyl transferase/acyl hydrolase/lysophospholipase AFK25_05135 9618fe3f8b8fa43c57fbd528d143d0ce 258 Gene3D G3DSA:3.40.1090.10 1 96 2.8E-27 T 11-10-2018 AFK25_05135 9618fe3f8b8fa43c57fbd528d143d0ce 258 Gene3D G3DSA:3.40.1090.10 97 212 1.1E-23 T 11-10-2018 AFK25_05135 9618fe3f8b8fa43c57fbd528d143d0ce 258 Pfam PF01734 Patatin-like phospholipase 5 161 2.0E-24 T 11-10-2018 IPR002641 Patatin-like phospholipase domain GO:0006629 AFK25_08995 9c5a21304d2c39ceb6a37d0e8e8113d0 298 ProDom PD128584 YPHB BH1976 TRANSMEMBRANE MEMBRANE SEAA 1 287 7.0E-140 T 11-10-2018 AFK25_08995 9c5a21304d2c39ceb6a37d0e8e8113d0 298 Pfam PF14045 YIEGIA protein 8 287 3.5E-130 T 11-10-2018 IPR025918 YIEGIA protein AFK25_09100 664d0d9b972a73cd84e5906be494c8cf 86 PIRSF PIRSF010606 1 86 1.4E-40 T 11-10-2018 IPR016571 Spore coat assembly protein CotJB AFK25_09100 664d0d9b972a73cd84e5906be494c8cf 86 Pfam PF12652 CotJB protein 10 85 6.2E-28 T 11-10-2018 IPR024207 Spore coat assembly protein CotJB, domain AFK25_11750 cf71966c03739b7096215c6098a549bd 216 Pfam PF11167 Protein of unknown function (DUF2953) 122 173 4.8E-14 T 11-10-2018 IPR021338 Protein of unknown function DUF2953 AFK25_13390 a11fc66ca719b96ebc8b4d1546de74db 79 Pfam PF10439 Bacteriocin class II with double-glycine leader peptide 1 63 2.5E-12 T 11-10-2018 IPR019493 Bacteriocin, class IIb, lactacin-related GO:0042742 AFK25_01570 2f541eda2cefa97a47b512d82672e482 259 Pfam PF12704 MacB-like periplasmic core domain 19 224 7.4E-8 T 11-10-2018 IPR025857 MacB-like periplasmic core domain AFK25_05560 0537019522cf9c2ee4457d626263eb14 127 Pfam PF11068 YlqD protein 1 125 1.6E-32 T 11-10-2018 IPR021297 YlqD protein AFK25_02575 5cf580a1d1bbb288ef312335e1df1a6b 77 SUPERFAMILY SSF52833 1 74 1.72E-20 T 11-10-2018 IPR036249 Thioredoxin-like superfamily AFK25_02575 5cf580a1d1bbb288ef312335e1df1a6b 77 Pfam PF00462 Glutaredoxin 4 62 3.3E-17 T 11-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 AFK25_02575 5cf580a1d1bbb288ef312335e1df1a6b 77 Gene3D G3DSA:3.40.30.10 1 76 2.8E-25 T 11-10-2018 AFK25_11545 820e400186c1c9e4bcb3c4cddeb06a67 465 Pfam PF07261 Replication initiation and membrane attachment 339 397 6.8E-12 T 11-10-2018 IPR006343 DnaD domain AFK25_00175 a31b00dc83e208177dd6c27a75f1f635 474 Pfam PF03711 Orn/Lys/Arg decarboxylase, C-terminal domain 398 457 9.6E-12 T 11-10-2018 IPR008286 Orn/Lys/Arg decarboxylase, C-terminal GO:0003824 AFK25_00175 a31b00dc83e208177dd6c27a75f1f635 474 SUPERFAMILY SSF53383 6 378 3.72E-82 T 11-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AFK25_00175 a31b00dc83e208177dd6c27a75f1f635 474 Gene3D G3DSA:3.90.100.10 378 472 3.4E-17 T 11-10-2018 AFK25_00175 a31b00dc83e208177dd6c27a75f1f635 474 Gene3D G3DSA:3.90.1150.150 279 369 2.0E-111 T 11-10-2018 AFK25_00175 a31b00dc83e208177dd6c27a75f1f635 474 Pfam PF01276 Orn/Lys/Arg decarboxylase, major domain 6 309 1.0E-83 T 11-10-2018 IPR000310 Orn/Lys/Arg decarboxylase, major domain GO:0003824 AFK25_00175 a31b00dc83e208177dd6c27a75f1f635 474 Gene3D G3DSA:3.40.640.10 48 278 2.0E-111 T 11-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AFK25_07950 6d0d4b8156cd5c7a841cd40d73a45974 389 Pfam PF02653 Branched-chain amino acid transport system / permease component 50 377 6.3E-43 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFK25_10830 a915eddc85c05636a5cd6216342f2dbb 65 Pfam PF11146 Protein of unknown function (DUF2905) 3 61 4.7E-25 T 11-10-2018 IPR021320 Protein of unknown function DUF2905 AFK25_03800 12dc9214dcec1ea54a0ad2665b1669e4 365 Gene3D G3DSA:1.10.10.10 150 255 3.9E-5 T 11-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AFK25_03800 12dc9214dcec1ea54a0ad2665b1669e4 365 SUPERFAMILY SSF88659 133 216 1.5E-5 T 11-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AFK25_05710 1eaf5d362224718ceecb18088773a9d7 75 Pfam PF06289 Flagellar protein (FlbD) 1 58 9.4E-27 T 11-10-2018 IPR009384 Swarming motility protein SwrD-like AFK25_07615 f58f22d8c9f51bdda5df7515ce34d8c6 256 Pfam PF07070 SpoOM protein 4 214 7.4E-83 T 11-10-2018 IPR009776 Sporulation stage 0, protein M AFK25_11630 192d3f78d67154b713f3d34e2e9496f9 132 Pfam PF04186 FxsA cytoplasmic membrane protein 9 114 1.1E-34 T 11-10-2018 IPR007313 FxsA cytoplasmic membrane protein GO:0016020 AFK25_00135 b31517d90ac8e3fbb8bd45fa44170f34 73 Pfam PF10704 Protein of unknown function (DUF2508) 2 69 3.0E-23 T 11-10-2018 IPR019644 Protein of unknown function DUF2508 AFK25_08315 ad4c96e430ca3c1148c965fe45ec11fc 108 Pfam PF12986 Domain of unknown function (DUF3870) 5 97 5.9E-31 T 11-10-2018 IPR024617 Domain of unknown function DUF3870 AFK25_03150 0dacb61f6ae53c8200775443af0a7301 242 Pfam PF04240 Carotenoid biosynthesis protein 35 224 2.5E-37 T 11-10-2018 IPR007354 Carotene biosynthesis associated membrane protein AFK25_03905 221131ee1495500caaa4afbbc4e276a0 342 Pfam PF12762 ISXO2-like transposase domain 148 303 7.0E-18 T 11-10-2018 IPR024445 ISXO2-like transposase domain AFK25_03905 221131ee1495500caaa4afbbc4e276a0 342 SMART SM01126 147 315 4.0E-38 T 11-10-2018 IPR024445 ISXO2-like transposase domain AFK25_03905 221131ee1495500caaa4afbbc4e276a0 342 Pfam PF12760 Transposase zinc-ribbon domain 46 84 1.0E-7 T 11-10-2018 IPR024442 Transposase, zinc-ribbon AFK25_01565 f81e9a5ea6206733db4f20e665e405d1 295 Pfam PF01610 Transposase 144 282 4.9E-13 T 11-10-2018 IPR002560 Transposase IS204/IS1001/IS1096/IS1165, DDE domain AFK25_02415 9d68630e869bb9c52a8a051adc1aca66 184 Pfam PF06763 Prophage minor tail protein Z (GPZ) 21 182 6.2E-16 T 11-10-2018 IPR010633 Bacteriophage lambda, GpZ, minor tail AFK25_14615 e29532528c0c43cd7a3913d85135574f 234 Pfam PF04474 Protein of unknown function (DUF554) 4 227 2.5E-75 T 11-10-2018 IPR007563 Protein of unknown function DUF554 AFK25_00190 7b14609e11c388ca25e0ca445c44a701 275 Pfam PF04468 PSP1 C-terminal conserved region 61 146 6.3E-32 T 11-10-2018 IPR007557 PSP1, C-terminal AFK25_05155 a209437d0603356e1f634492313bfd46 57 Hamap MF_00340 50S ribosomal protein L32 [rpmF]. 1 55 20.438 T 11-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_05155 a209437d0603356e1f634492313bfd46 57 SUPERFAMILY SSF57829 1 55 2.08E-22 T 11-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AFK25_05155 a209437d0603356e1f634492313bfd46 57 TIGRFAM TIGR01031 rpmF_bact: ribosomal protein bL32 2 55 3.8E-28 T 11-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_05155 a209437d0603356e1f634492313bfd46 57 Pfam PF01783 Ribosomal L32p protein family 2 57 3.2E-27 T 11-10-2018 IPR002677 Ribosomal protein L32p GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AFK25_02700 02a9b3fd35cc364ec9e8ac6545495d75 204 Gene3D G3DSA:3.20.20.70 2 201 1.2E-55 T 11-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AFK25_02700 02a9b3fd35cc364ec9e8ac6545495d75 204 Pfam PF02581 Thiamine monophosphate synthase 19 179 4.7E-39 T 11-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFK25_02700 02a9b3fd35cc364ec9e8ac6545495d75 204 SUPERFAMILY SSF51391 23 196 4.71E-44 T 11-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AFK25_13870 e39b1de03c11fe6eb708341ae72996d4 125 ProDom PD020811 ATP SYNTHASE I ION HYDROLASE SUBUNIT I CF0 MEMBRANE HYDROGEN 23 121 1.0E-21 T 11-10-2018 AFK25_13870 e39b1de03c11fe6eb708341ae72996d4 125 Pfam PF03899 ATP synthase I chain 13 105 3.5E-18 T 11-10-2018 IPR005598 ATP synthase protein I AFK25_02695 7ca3257b756efa03422258899545e9bd 264 Pfam PF02361 Cobalt transport protein 9 220 1.1E-28 T 11-10-2018 IPR003339 ABC/ECF transporter, transmembrane component AFK25_07925 117378de77fe9fe3b7b2a107299a2573 220 Gene3D G3DSA:3.40.630.30 13 219 2.1E-56 T 11-10-2018 AFK25_07925 117378de77fe9fe3b7b2a107299a2573 220 SUPERFAMILY SSF55729 19 149 1.61E-18 T 11-10-2018 IPR016181 Acyl-CoA N-acyltransferase AFK25_07925 117378de77fe9fe3b7b2a107299a2573 220 Pfam PF00583 Acetyltransferase (GNAT) family 28 147 8.3E-12 T 11-10-2018 IPR000182 GNAT domain AFK25_04765 d8b0f5745b94300f2744e9a5fff98767 146 Pfam PF14177 YkyB-like protein 7 138 4.9E-66 T 11-10-2018 IPR025552 YkyB-like protein AFK25_03540 09cadf10d9c9f183ab6357d1f44b9fd2 124 Hamap MF_01861 UPF0738 protein . 7 124 27.725 T 11-10-2018 IPR020908 Uncharacterised protein family UPF0738 AFK25_04440 c126c6bbd3644a5856388963f1ca42e2 473 Pfam PF13520 Amino acid permease 6 428 1.5E-50 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFK25_04440 c126c6bbd3644a5856388963f1ca42e2 473 PIRSF PIRSF006060 1 472 1.1E-51 T 11-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AFK25_04440 c126c6bbd3644a5856388963f1ca42e2 473 Gene3D G3DSA:1.20.1740.10 1 473 2.6E-62 T 11-10-2018 AFK25_03410 d8a025abe0cd2c6a71095b0faec2c91f 59 Pfam PF11151 Protein of unknown function (DUF2929) 1 55 6.2E-20 T 11-10-2018 IPR021324 Protein of unknown function DUF2929 AFK25_05090 cab3a462493614ed9c04b8bbe66a8b83 80 Pfam PF14003 YlbE-like protein 13 73 3.7E-26 T 11-10-2018 IPR025613 YlbE-like protein AFK25_01230 7ccc988e5c47efe1b9887b3941adb8dd 57 Pfam PF14146 Domain of unknown function (DUF4305) 14 50 9.1E-17 T 11-10-2018 IPR025426 Protein of unknown function DUF4305 AFK25_11685 a436dec7465f80c662139680fc9175e5 99 Pfam PF14007 YtpI-like protein 5 90 4.1E-37 T 11-10-2018 IPR025618 YtpI-like protein AFK25_14325 af2371297672468b95cd5bb6f7b2e0c7 372 Pfam PF12704 MacB-like periplasmic core domain 19 206 3.9E-6 T 11-10-2018 IPR025857 MacB-like periplasmic core domain AFK25_14325 af2371297672468b95cd5bb6f7b2e0c7 372 Pfam PF02687 FtsX-like permease family 278 365 1.0E-11 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFK25_03670 dc921e4b0ab84c19905ea704cbd135d3 68 Pfam PF07870 Protein of unknown function (DUF1657) 7 55 1.6E-15 T 11-10-2018 IPR012452 Protein of unknown function DUF1657 AFK25_12835 fee89d6efafb235be7e8438edf3f9b2c 350 Gene3D G3DSA:1.20.58.790 32 121 6.4E-26 T 11-10-2018 AFK25_12835 fee89d6efafb235be7e8438edf3f9b2c 350 Gene3D G3DSA:1.20.58.770 190 251 1.7E-5 T 11-10-2018 AFK25_13545 34d98db6c7bbe10aaa1537771bc6e871 135 Pfam PF14183 YwpF-like protein 2 129 3.0E-44 T 11-10-2018 IPR025573 YwpF-like protein AFK25_08415 2dc9065c906d2b914df2e291e54a108d 324 SUPERFAMILY SSF110296 59 318 4.32E-27 T 11-10-2018 AFK25_08415 2dc9065c906d2b914df2e291e54a108d 324 Gene3D G3DSA:2.130.10.10 62 323 1.2E-15 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFK25_08415 2dc9065c906d2b914df2e291e54a108d 324 Pfam PF15902 Sortilin, neurotensin receptor 3, 127 263 2.9E-10 T 11-10-2018 IPR031778 Sortilin, N-terminal AFK25_04480 7b561c5d7dcadeb84432f494e7e7c333 324 Gene3D G3DSA:2.130.10.10 238 323 5.4E-6 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFK25_04480 7b561c5d7dcadeb84432f494e7e7c333 324 Gene3D G3DSA:2.130.10.10 31 237 2.3E-18 T 11-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AFK25_04480 7b561c5d7dcadeb84432f494e7e7c333 324 SUPERFAMILY SSF51004 26 320 7.59E-28 T 11-10-2018 IPR011048 Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily AFK25_04555 7da860558b33a223127800cb2133683a 80 Pfam PF14166 YueH-like protein 2 79 1.1E-29 T 11-10-2018 IPR020260 Uncharacterised protein family YueH AFK25_04555 7da860558b33a223127800cb2133683a 80 ProDom PD060056 YUEH 1 80 9.0E-12 T 11-10-2018 IPR020260 Uncharacterised protein family YueH AFK25_10670 25c98af293536a833a0809a9ee149abe 97 Pfam PF06949 Protein of unknown function (DUF1292) 13 89 1.3E-17 T 11-10-2018 IPR009711 Uncharacterised protein family UPF0473 AFK25_10670 25c98af293536a833a0809a9ee149abe 97 Hamap MF_01448 UPF0473 protein . 4 91 21.932 T 11-10-2018 IPR009711 Uncharacterised protein family UPF0473 AFK25_03445 60e8e20418fc4dd056c9473d3d656357 246 Hamap MF_01860 UPF0736 protein . 1 246 49.794 T 11-10-2018 IPR020909 UPF0736 AFK25_03445 60e8e20418fc4dd056c9473d3d656357 246 Pfam PF12227 Protein of unknown function (DUF3603) 35 246 1.3E-111 T 11-10-2018 IPR020909 UPF0736 AFK25_04580 6609a9cea7398d57051ef34a7d9d8f36 71 Pfam PF11148 Protein of unknown function (DUF2922) 2 66 2.6E-27 T 11-10-2018 IPR021321 Protein of unknown function DUF2922 AFK25_07175 53581dfda38781f10fa8018e8cf7c6e3 83 Pfam PF10751 Protein of unknown function (DUF2535) 1 83 2.4E-42 T 11-10-2018 IPR019687 Protein of unknown function DUF2535 AFK25_09250 70c174e840cbe2ca35c68c8cfc81595f 197 Pfam PF07670 Nucleoside recognition 43 150 2.7E-12 T 11-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 AFK25_12710 b49067c317f685a2d8ff81d3e9974531 272 Pfam PF01925 Sulfite exporter TauE/SafE 6 265 3.7E-56 T 11-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AFK25_03080 3b44e2e5261d21fb692324f2239bc6d6 73 Pfam PF10676 Spore germination protein gerPA/gerPF 1 72 6.3E-31 T 11-10-2018 IPR019618 Spore germination protein GerPA/GerPF AFK25_02345 f900889829990a9bf33c7f1fd94e7884 147 TIGRFAM TIGR01637 phage_arpU: phage transcriptional regulator, ArpU family 5 139 8.6E-41 T 11-10-2018 IPR006524 Transcription activator, ArpU family AFK25_08490 8e1a4676d4bc07b8ad7dbde9fed32bff 169 Pfam PF07681 DoxX 16 115 4.2E-11 T 11-10-2018 IPR032808 DoxX family AFK25_13465 6f1d1287a9abd70813da2e2309165f92 275 Pfam PF04754 Putative transposase, YhgA-like 4 102 8.4E-5 T 11-10-2018 IPR006842 Transposase (putative), YhgA-like AFK25_01790 2881b2a1634c0f5a1fa45d423b8fd6ba 258 Pfam PF14167 YfkD-like protein 27 258 4.5E-124 T 11-10-2018 IPR025548 YfkD-like protein AFK25_03070 a59fb02ee90b1b7211fa7b2e84d56ed5 194 Pfam PF10737 Spore germination protein GerPC 21 188 1.5E-61 T 11-10-2018 IPR019673 Spore germination protein GerPC AFK25_08120 0a9bfe9e1be16f192eac1185689590d5 156 Pfam PF13798 Protein of unknown function with PCYCGC motif 10 154 1.2E-69 T 11-10-2018 IPR025673 Protein of unknown function with PCYCGC motif AFK25_06565 b1796878e62cf069df262b833faf4274 315 Pfam PF03773 Predicted permease 22 312 1.6E-72 T 11-10-2018 IPR005524 Predicted permease DUF318 AFK25_03025 896dfc1b9ce5f77c40e9e83d52ede6bc 200 Pfam PF09335 SNARE associated Golgi protein 43 161 2.1E-21 T 11-10-2018 IPR032816 SNARE associated Golgi protein AFK25_10625 0248161aafa0ebc0478430603e5cae19 67 Pfam PF10750 Protein of unknown function (DUF2536) 2 66 9.3E-33 T 11-10-2018 IPR019686 Protein of unknown function DUF2536 AFK25_06210 b4d0e1259ac9627a5dd24ade92f24598 70 Pfam PF11211 Protein of unknown function (DUF2997) 7 53 1.3E-16 T 11-10-2018 IPR021375 Protein of unknown function DUF2997 AFK25_02440 5d05590dc4132eca99806a2cccbcd25f 101 Pfam PF10109 Phage tail assembly chaperone proteins, E, or 41 or 14 4 88 3.2E-10 T 11-10-2018 IPR019289 Bacteriophage tail protein Gp41, putative AFK25_09265 545be94b8c4a9e61fac6b5e4fea13d90 162 Pfam PF13047 Protein of unknown function (DUF3907) 10 156 2.1E-64 T 11-10-2018 IPR025013 Protein of unknown function DUF3907 AFK25_14120 75305b95d5111beeacfc33e420646ca0 187 Pfam PF09335 SNARE associated Golgi protein 34 144 1.1E-16 T 11-10-2018 IPR032816 SNARE associated Golgi protein AFK25_10630 3016795882363f95278afeaa27e01cd5 199 Pfam PF07423 Protein of unknown function (DUF1510) 59 192 3.5E-51 T 11-10-2018 IPR009988 Protein of unknown function DUF1510 AFK25_13260 4091e51799dbcdb4494a5603d021eadb 135 TIGRFAM TIGR03826 YvyF: flagellar operon protein TIGR03826 1 134 2.7E-50 T 11-10-2018 IPR022258 Flagellar operon protein YvyF AFK25_06940 5421344f4d7c184284f6f194b2c46079 156 Pfam PF02681 Divergent PAP2 family 2 141 1.1E-44 T 11-10-2018 IPR003832 Protein of unknown function DUF212 AFK25_03955 737bf25fa8a3fdc2d51328d37ae7c69d 242 Gene3D G3DSA:3.30.2010.10 145 235 2.6E-20 T 11-10-2018 AFK25_03955 737bf25fa8a3fdc2d51328d37ae7c69d 242 Pfam PF01863 Protein of unknown function DUF45 23 234 8.8E-56 T 11-10-2018 IPR002725 Protein of unknown function DUF45 AFK25_14045 6c36cdc67383c0aa356a36209df562ec 122 Gene3D G3DSA:1.20.210.10 1 122 1.9E-12 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_14045 6c36cdc67383c0aa356a36209df562ec 122 SUPERFAMILY SSF81442 8 119 1.7E-10 T 11-10-2018 IPR036927 Cytochrome c oxidase-like, subunit I superfamily GO:0055114 KEGG: 00190+1.9.3.1|MetaCyc: PWY-3781|MetaCyc: PWY-4521|MetaCyc: PWY-6692|MetaCyc: PWY-7279|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AFK25_04425 a044432258be2094024a5e25643fb797 244 Pfam PF02535 ZIP Zinc transporter 92 240 2.6E-14 T 11-10-2018 IPR003689 Zinc/iron permease GO:0016020|GO:0030001|GO:0046873|GO:0055085 AFK25_09600 bb3899f9a4df5751f79121696a3f486c 220 Pfam PF03379 CcmB protein 7 209 1.6E-22 T 11-10-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 AFK25_13700 bdd7f750951c52fab349564a673a24fe 233 Pfam PF02397 Bacterial sugar transferase 32 220 1.2E-73 T 11-10-2018 IPR003362 Bacterial sugar transferase AFK25_02975 b1bb0befcbe022b7d4dc097fc17a47a7 324 Pfam PF02653 Branched-chain amino acid transport system / permease component 5 291 1.2E-30 T 11-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AFK25_03060 e40563183e4889ac48f658fa8368b058 132 ProDom PD031981 GERMINATION SPORE GERPE PE PROBABLE SPORULATION 5 118 2.0E-24 T 11-10-2018 IPR024496 Spore germination protein GerPE AFK25_03060 e40563183e4889ac48f658fa8368b058 132 Pfam PF10970 Spore germination protein GerPE 5 120 7.9E-38 T 11-10-2018 IPR024496 Spore germination protein GerPE AFK25_10990 bc1f6a82613eee13bd07d755bbe9b0f7 208 Pfam PF04350 Pilus assembly protein, PilO 30 175 6.3E-6 T 11-10-2018 IPR007445 Pilus assembly protein, PilO AFK25_02435 04955fab4f9aae5cc13dc3f95a3bedb8 175 Pfam PF04985 Phage tail tube protein FII 7 174 1.7E-47 T 11-10-2018 IPR006498 Tail tube protein AFK25_02475 26d329d1f37bc03bcb07e8b6348465bf 372 Pfam PF04865 Baseplate J-like protein 72 330 4.9E-64 T 11-10-2018 IPR006949 Baseplate protein J-like AFK25_02475 26d329d1f37bc03bcb07e8b6348465bf 372 PIRSF PIRSF020481 7 369 2.1E-48 T 11-10-2018 IPR014507 Baseplate assembly protein J, predicted AFK25_06915 7e29c8359ee7e3dd8fc4f20fa7ea4940 47 Pfam PF08179 Small acid-soluble spore protein P family 1 42 7.9E-23 T 11-10-2018 IPR012614 Small acid-soluble spore protein, SspP GO:0030435 AFK25_06915 7e29c8359ee7e3dd8fc4f20fa7ea4940 47 Hamap MF_00666 Small, acid-soluble spore protein P [sspP]. 1 47 18.335 T 11-10-2018 IPR012614 Small acid-soluble spore protein, SspP GO:0030435 AFK25_09850 163fcbbb3f00ef1c6a1575da54cad568 131 Pfam PF03780 Asp23 family, cell envelope-related function 15 120 9.9E-38 T 11-10-2018 IPR005531 Alkaline shock protein Asp23 AFK25_05150 b2abd7eb7435e6063c1bbe2d08d85266 171 Pfam PF02620 Uncharacterized ACR, COG1399 56 164 3.7E-20 T 11-10-2018 IPR003772 Large ribosomal RNA subunit accumulation protein YceD AFK25_13365 1315f0d7b5159eae4266a91588a7da3b 240 Pfam PF02517 CAAX protease self-immunity 147 231 3.3E-15 T 11-10-2018 IPR003675 CAAX amino terminal protease GO:0016020 Reactome: R-HSA-5689880 AFK25_14575 708e37272db46b2f01ab6991a39ea7ce 310 Pfam PF09991 Predicted membrane protein (DUF2232) 15 300 6.7E-71 T 11-10-2018 IPR018710 Protein of unknown function DUF2232 AFK25_13915 b8bd9ea294367630f05af58a0a731af6 181 Pfam PF02659 Putative manganese efflux pump 31 178 2.0E-41 T 11-10-2018 IPR003810 Putative manganese efflux pump AFK25_13915 b8bd9ea294367630f05af58a0a731af6 181 Hamap MF_01521 Probable manganese efflux pump MntP [mntP]. 3 181 21.705 T 11-10-2018 IPR022929 Putative manganese efflux pump MntP AFK25_08420 2531fa691524ed129960b0d7897b1c63 184 Pfam PF09335 SNARE associated Golgi protein 33 151 2.1E-21 T 11-10-2018 IPR032816 SNARE associated Golgi protein AFK25_01100 e13c67b10850852d3e593f8fad16d29d 93 Gene3D G3DSA:1.10.1220.10 1 93 1.5E-42 T 11-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 AFK25_01450 745497ddfd04ef54deb8277346e94628 99 TIGRFAM TIGR02901 QoxD: cytochrome aa3 quinol oxidase, subunit IV 3 96 7.8E-34 T 11-10-2018 IPR014250 Quinol oxidase subunit IV GO:0016021|GO:0016682|GO:0042773 AFK25_01450 745497ddfd04ef54deb8277346e94628 99 Pfam PF03626 Prokaryotic Cytochrome C oxidase subunit IV 12 85 5.2E-12 T 11-10-2018 IPR005171 Cytochrome C oxidase subunit IV, prokaryotes GO:0016021 AFK25_08135 047cb84f588b2a5ab9ec339600c8663b 155 SUPERFAMILY SSF58113 5 129 1.57E-10 T 11-10-2018 AFK25_08135 047cb84f588b2a5ab9ec339600c8663b 155 Gene3D G3DSA:1.20.120.20 3 146 7.6E-13 T 11-10-2018 AFK25_01560 7d44f2a4d392b4c45761e5bda89cd495 588 Pfam PF02687 FtsX-like permease family 7 102 1.0E-12 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFK25_01560 7d44f2a4d392b4c45761e5bda89cd495 588 Pfam PF02687 FtsX-like permease family 493 580 9.4E-10 T 11-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AFK25_06555 2eef4e6d95a1f2e034c7e6f0d2fc3c77 135 Pfam PF04138 GtrA-like protein 16 130 1.7E-29 T 11-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 AFK25_13505 e9297aa153379feef19f8f407971d038 527 Pfam PF00395 S-layer homology domain 480 517 1.7E-6 T 11-10-2018 IPR001119 S-layer homology domain AFK25_13505 e9297aa153379feef19f8f407971d038 527 Pfam PF00395 S-layer homology domain 419 458 3.4E-10 T 11-10-2018 IPR001119 S-layer homology domain AFK25_13505 e9297aa153379feef19f8f407971d038 527 Pfam PF00395 S-layer homology domain 368 398 6.9E-4 T 11-10-2018 IPR001119 S-layer homology domain AFK25_02235 ec3b44a138d8603d24f4c44c319afc10 259 Pfam PF08862 Domain of unknown function DUF1829 163 250 5.9E-31 T 11-10-2018 IPR014961 Domain of unknown function DUF1829 AFK25_02235 ec3b44a138d8603d24f4c44c319afc10 259 Pfam PF08861 Domain of unknown function DUF1828 33 125 9.9E-26 T 11-10-2018 IPR014960 Domain of unknown function DUF1828 AFK25_07665 6c64ba1124e2ae8c2d7b3b7f6444fca2 74 Pfam PF13040 Fur-regulated basic protein B 33 69 2.3E-16 T 11-10-2018 IPR025004 Transcriptional regulatory protein SenN/SenS AFK25_06030 201b6b0b0c5ecd29ef6a462eac53d225 406 Pfam PF02447 GntP family permease 20 224 1.7E-15 T 11-10-2018 IPR003474 Gluconate transporter GO:0015128|GO:0016020|GO:0035429 AFK25_04010 854c3d2502284a7e1007ed6e7e114bde 417 Pfam PF14281 PD-(D/E)XK nuclease superfamily 35 231 4.6E-32 T 11-10-2018 IPR029470 PD-(D/E)XK nuclease superfamily 4 AFK25_04595 ce424f6d3fba85922f9dcedfe8e5028b 140 Pfam PF04039 Domain related to MnhB subunit of Na+/H+ antiporter 7 130 1.3E-35 T 11-10-2018 IPR007182 Na+/H+ antiporter MnhB subunit-related protein AFK25_00780 83c98efcee6caa6387eeb956bff29a13 134 Pfam PF10730 Protein of unknown function (DUF2521) 3 134 6.5E-34 T 11-10-2018 IPR019667 Uncharacterised protein family YbaK AFK25_09610 49c8d5bc9af843ad0dd2dcfc719cbace 124 Pfam PF03918 Cytochrome C biogenesis protein 57 122 3.4E-13 T 11-10-2018 IPR005616 CcmH/CycL/Ccl2/NrfF family AFK25_13045 f0f55bf2aeffca7951ec62da21b596de 114 Pfam PF04020 Mycobacterial 4 TMS phage holin, superfamily IV 1 105 1.8E-25 T 11-10-2018 IPR007165 Mycobacterial 4 TMS phage holin, superfamily IV AFK25_05700 72e328ef54a12f947518beddae9d3a2f 155 Pfam PF03963 Flagellar hook capping protein - N-terminal region 15 73 2.0E-21 T 11-10-2018 IPR005648 Flagellar hook capping protein AFK25_08460 7eafc3d48b1b14483daddd9111151776 292 SUPERFAMILY SSF51445 69 258 9.56E-8 T 11-10-2018 IPR017853 Glycoside hydrolase superfamily AFK25_03615 3d6c19e10dd81ed355971354ca52e8b2 107 Pfam PF07098 Protein of unknown function (DUF1360) 8 105 1.5E-37 T 11-10-2018 IPR010773 Mycobacterium phage PG1, Gp7 AFK25_06605 01ea3c4f8643acb6d55f423aa8faeafb 243 Pfam PF03692 Putative zinc- or iron-chelating domain 74 176 1.5E-7 T 11-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein AFK25_11265 ea1aba1fcacef6686aedf061a770076a 466 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 47 199 1.8E-6 T 11-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like AFK25_02230 433da94df646bd3c2548ebe7302230bc 159 Pfam PF06114 IrrE N-terminal-like domain 53 148 3.8E-11 T 11-10-2018 IPR010359 IrrE N-terminal-like domain AFK25_04600 c7b2db9bb5b5f6aa0331f1b708daf195 110 Pfam PF00420 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L 5 107 4.0E-31 T 11-10-2018 IPR039428 NADH-ubiquinone oxidoreductase chain 4L/Mnh complex subunit C1-like AFK25_03095 c551e3c2c8ec3d12eee565ee8aee1e9d 369 Pfam PF04235 Protein of unknown function (DUF418) 217 365 1.1E-43 T 11-10-2018 IPR007349 Domain of unknown function DUF418