locus-tag	class	description
BBF96_00040	COG3885	ferrous iron binding
BBF96_00040	COG2078	PFAM AMMECR1 domain protein
BBF96_00045	COG0697	spore germination
BBF96_00065	COG1063	alcohol dehydrogenase
BBF96_00070	COG0156	8-amino-7-oxononanoate synthase activity
BBF96_00075	COG1595	DNA-templated transcription, initiation
BBF96_00095	COG0235	Class ii aldolase
BBF96_00100	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BBF96_00110	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BBF96_00115	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BBF96_00125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BBF96_00200	COG0129	dihydroxy-acid dehydratase activity
BBF96_00210	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BBF96_00215	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BBF96_00220	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BBF96_00225	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BBF96_00240	COG3875	lactate racemase activity
BBF96_00245	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BBF96_00250	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBF96_00255	COG0800	Aldolase
BBF96_00260	COG1414	Transcriptional regulator
BBF96_00270	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BBF96_00285	COG0736	holo-[acyl-carrier-protein] synthase activity
BBF96_00290	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BBF96_00290	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BBF96_00295	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BBF96_00300	COG1073	alpha beta
BBF96_00315	COG2337	Toxic component of a toxin-antitoxin (TA) module
BBF96_00325	COG1473	amidohydrolase
BBF96_00335	COG1228	amidohydrolase
BBF96_00350	COG0802	atpase or kinase
BBF96_00355	COG1214	PFAM Peptidase M22, glycoprotease
BBF96_00360	COG0456	acetyltransferase
BBF96_00375	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BBF96_00380	COG0459	protein refolding
BBF96_00385	COG2515	1-aminocyclopropane-1-carboxylate deaminase
BBF96_00390	COG1131	(ABC) transporter
BBF96_00405	COG1404	Belongs to the peptidase S8 family
BBF96_00410	COG0519	Catalyzes the synthesis of GMP from XMP
BBF96_00410	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BBF96_00415	COG2252	PERMEase
BBF96_00435	COG0521	Mo-molybdopterin cofactor biosynthetic process
BBF96_00440	COG3457	Alanine racemase
BBF96_00445	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BBF96_00450	COG4496	protein, YerC YecD
BBF96_00455	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BBF96_00460	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BBF96_00465	COG2011	ABC-type metal ion transport system permease component
BBF96_00475	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BBF96_00490	COG1091	dTDP-4-dehydrorhamnose reductase activity
BBF96_00495	COG0438	transferase activity, transferring glycosyl groups
BBF96_00505	COG0438	transferase activity, transferring glycosyl groups
BBF96_00505	COG1216	Glycosyl transferase, family 2
BBF96_00515	COG0438	transferase activity, transferring glycosyl groups
BBF96_00515	COG1216	Glycosyl transferase, family 2
BBF96_00520	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BBF96_00525	COG4641	Protein conserved in bacteria
BBF96_00535	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BBF96_00540	COG1280	lysine exporter protein (LysE YggA)
BBF96_00690	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BBF96_00695	COG0617	tRNA 3'-terminal CCA addition
BBF96_00715	COG1131	(ABC) transporter
BBF96_00720	COG1122	ATPase activity
BBF96_00735	COG1131	(ABC) transporter
BBF96_00775	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BBF96_00790	COG0824	Thioesterase
BBF96_00835	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BBF96_00845	COG0739	heme binding
BBF96_00850	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BBF96_00855	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BBF96_00860	COG0154	amidase activity
BBF96_00865	COG0454	-acetyltransferase
BBF96_00870	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BBF96_00910	COG0673	inositol 2-dehydrogenase activity
BBF96_00915	COG0318	PFAM AMP-dependent synthetase and ligase
BBF96_00920	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BBF96_00925	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BBF96_00940	COG0534	Mate efflux family protein
BBF96_00950	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BBF96_00955	COG1309	transcriptional regulator
BBF96_00960	COG0574	Belongs to the PEP-utilizing enzyme family
BBF96_00960	COG3848	Pyruvate phosphate dikinase
BBF96_00965	COG2814	Major facilitator Superfamily
BBF96_00975	COG0697	spore germination
BBF96_00980	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BBF96_00985	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BBF96_00990	COG1984	allophanate hydrolase subunit 2
BBF96_01020	COG1164	Oligoendopeptidase f
BBF96_01025	COG0737	Belongs to the 5'-nucleotidase family
BBF96_01045	COG1131	(ABC) transporter
BBF96_01060	COG1131	(ABC) transporter
BBF96_01070	COG0500	methyltransferase
BBF96_01080	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BBF96_01090	COG2005	Transcriptional regulator
BBF96_01095	COG0725	ABC transporter, periplasmic molybdate-binding protein
BBF96_01100	COG4149	molybdate abc transporter
BBF96_01110	COG0017	Asparaginyl-tRNA synthetase
BBF96_01115	COG0697	spore germination
BBF96_01120	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
BBF96_01135	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBF96_01140	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BBF96_01170	COG0564	pseudouridine synthase activity
BBF96_01175	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BBF96_01180	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BBF96_01185	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BBF96_01190	COG1404	Belongs to the peptidase S8 family
BBF96_01200	COG1404	Belongs to the peptidase S8 family
BBF96_01205	COG1032	radical SAM domain protein
BBF96_01210	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BBF96_01220	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BBF96_01230	COG2431	L-lysine efflux transmembrane transporter activity
BBF96_01240	COG1132	(ABC) transporter
BBF96_01245	COG1132	(ABC) transporter
BBF96_01270	COG4134	Bacterial extracellular solute-binding protein
BBF96_01275	COG1176	ABC-type spermidine putrescine transport system, permease component I
BBF96_01280	COG4208	sulfate ABC transporter
BBF96_01285	COG3842	ATPase activity
BBF96_01295	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BBF96_01295	COG2508	Transcriptional regulator
BBF96_01310	COG2391	methyltransferase activity
BBF96_01320	COG2897	thiosulfate sulfurtransferase activity
BBF96_01325	COG0398	Pfam SNARE associated Golgi protein
BBF96_01420	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BBF96_01420	COG2199	diguanylate cyclase activity
BBF96_01430	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BBF96_01440	COG0840	transmembrane signaling receptor activity
BBF96_01445	COG1136	(ABC) transporter
BBF96_01450	COG0577	efflux transmembrane transporter activity
BBF96_01450	COG1136	(ABC) transporter
BBF96_01455	COG4591	ABC-type transport system involved in lipoprotein release permease component
BBF96_01480	COG1846	Transcriptional regulator
BBF96_01480	COG1940	carbohydrate kinase activity
BBF96_01485	COG1082	Xylose isomerase domain protein TIM barrel
BBF96_01490	COG1070	Carbohydrate kinase
BBF96_01495	COG4213	ABC transporter substrate-binding protein
BBF96_01505	COG4214	carbohydrate transport
BBF96_01520	COG0653	protein targeting
BBF96_01540	COG0840	transmembrane signaling receptor activity
BBF96_01545	COG0215	cysteine-tRNA ligase activity
BBF96_01550	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BBF96_01570	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BBF96_01575	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
BBF96_01580	COG3959	Transketolase, thiamine diphosphate binding domain
BBF96_01585	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BBF96_01600	COG0793	Belongs to the peptidase S41A family
BBF96_01615	COG2247	cell wall binding repeat
BBF96_01615	COG0860	N-Acetylmuramoyl-L-alanine amidase
BBF96_01635	COG0622	Phosphoesterase
BBF96_01645	COG0556	nucleotide-excision repair
BBF96_01650	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BBF96_01665	COG2182	Extracellular solute-binding protein
BBF96_01670	COG1175	transmembrane transport
BBF96_01675	COG3833	ABC-type maltose transport systems, permease component
BBF96_01680	COG0366	Alpha amylase catalytic
BBF96_01685	COG0322	excinuclease ABC activity
BBF96_01690	COG1175	transmembrane transport
BBF96_01695	COG0395	ABC-type sugar transport system, permease component
BBF96_01710	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BBF96_01735	COG1950	PFAM Membrane protein of
BBF96_01745	COG1937	Protein conserved in bacteria
BBF96_01750	COG2217	Heavy metal translocating P-type atpase
BBF96_01755	COG3086	response to oxidative stress
BBF96_01760	COG2608	mercury ion transmembrane transporter activity
BBF96_01775	COG0644	oxidoreductase
BBF96_01780	COG0561	phosphatase activity
BBF96_01785	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BBF96_01790	COG0438	transferase activity, transferring glycosyl groups
BBF96_01805	COG1940	carbohydrate kinase activity
BBF96_01810	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BBF96_01845	COG2264	protein methyltransferase activity
BBF96_01855	COG1543	Belongs to the glycosyl hydrolase 57 family
BBF96_01860	COG0438	transferase activity, transferring glycosyl groups
BBF96_01865	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BBF96_01890	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BBF96_01935	COG1575	Belongs to the MenA family. Type 1 subfamily
BBF96_01945	COG1131	(ABC) transporter
BBF96_01955	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BBF96_01975	COG1660	Displays ATPase and GTPase activities
BBF96_01980	COG0391	Required for morphogenesis under gluconeogenic growth conditions
BBF96_01985	COG1481	regulation of sporulation
BBF96_02030	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BBF96_02035	COG0148	phosphopyruvate hydratase activity
BBF96_02040	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BBF96_02045	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BBF96_02060	COG0778	Nitroreductase
BBF96_02070	COG0557	exoribonuclease II activity
BBF96_02075	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BBF96_02090	COG0840	transmembrane signaling receptor activity
BBF96_02100	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BBF96_02115	COG2172	sigma factor antagonist activity
BBF96_02125	COG2390	Transcriptional regulator
BBF96_02130	COG4869	propanediol catabolic process
BBF96_02135	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BBF96_02155	COG4656	Part of a membrane complex involved in electron transport
BBF96_02165	COG4577	Carbon dioxide concentrating mechanism carboxysome shell protein
BBF96_02170	COG0698	ribose 5-phosphate isomerase
BBF96_02185	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BBF96_02230	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BBF96_02245	COG0697	spore germination
BBF96_02260	COG1924	4 iron, 4 sulfur cluster binding
BBF96_02265	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BBF96_02270	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BBF96_02275	COG0747	negative chemotaxis
BBF96_02285	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBF96_02290	COG0617	tRNA 3'-terminal CCA addition
BBF96_02305	COG0180	Tryptophanyl-tRNA synthetase
BBF96_02310	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BBF96_02315	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BBF96_02325	COG3874	Sporulation protein YtfJ
BBF96_02330	COG1686	Belongs to the peptidase S11 family
BBF96_02345	COG1122	ATPase activity
BBF96_02350	COG1187	pseudouridine synthase activity
BBF96_02355	COG2359	stage V sporulation protein S
BBF96_02360	COG1196	nuclear chromosome segregation
BBF96_02370	COG0552	protein localization to endoplasmic reticulum
BBF96_02425	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BBF96_02430	COG0228	four-way junction DNA binding
BBF96_02440	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BBF96_02445	COG0336	Belongs to the RNA methyltransferase TrmD family
BBF96_02450	COG0335	large ribosomal subunit rRNA binding
BBF96_02455	COG0681	Belongs to the peptidase S26 family
BBF96_02480	COG0606	chelatase, subunit chli
BBF96_02485	COG0792	nuclease activity
BBF96_02495	COG0758	DNA mediated transformation
BBF96_02495	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BBF96_02505	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BBF96_02510	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BBF96_02515	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BBF96_02520	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BBF96_02525	COG4465	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor
BBF96_02530	COG2201	protein-glutamate methylesterase activity
BBF96_02535	COG0643	Histidine kinase
BBF96_02535	COG2198	Histidine kinase
BBF96_02540	COG0835	chemotaxis
BBF96_02545	COG1776	CheC inhibitor of MCP methylation
BBF96_02550	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BBF96_02555	COG0052	Belongs to the universal ribosomal protein uS2 family
BBF96_02560	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BBF96_02565	COG0528	UMP kinase activity
BBF96_02570	COG0233	cytoplasmic translational termination
BBF96_02580	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BBF96_02585	COG0575	Belongs to the CDS family
BBF96_02595	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BBF96_02600	COG0750	zinc metalloprotease
BBF96_02610	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BBF96_02615	COG0442	prolyl-tRNA aminoacylation
BBF96_02620	COG0463	Glycosyl transferase, family 2
BBF96_02625	COG1285	pathogenesis
BBF96_02630	COG2814	Major facilitator Superfamily
BBF96_02660	COG1132	(ABC) transporter
BBF96_02665	COG0779	Required for maturation of 30S ribosomal subunits
BBF96_02670	COG0195	Participates in both transcription termination and antitermination
BBF96_02675	COG2740	Nucleic-acid-binding protein implicated in transcription termination
BBF96_02685	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BBF96_02690	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BBF96_02695	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BBF96_02700	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BBF96_02705	COG0196	riboflavin kinase activity
BBF96_02720	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BBF96_02725	COG1185	polyribonucleotide nucleotidyltransferase activity
BBF96_02730	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
BBF96_02735	COG1199	ATP-dependent helicase activity
BBF96_02740	COG3773	Cell wall hydrolase
BBF96_02740	COG3409	Peptidoglycan-binding domain 1 protein
BBF96_02745	COG3706	GGDEF domain
BBF96_02755	COG0726	polysaccharide deacetylase
BBF96_02760	COG0726	polysaccharide deacetylase
BBF96_02765	COG2720	vancomycin resistance protein
BBF96_02800	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BBF96_02805	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BBF96_02810	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BBF96_02815	COG0527	aspartate kinase activity
BBF96_02820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBF96_02825	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBF96_02830	COG1353	crispr-associated protein
BBF96_02840	COG1337	RAMP superfamily
BBF96_02865	COG0011	TIGRFAM Protein of
BBF96_02870	COG0740	serine-type endopeptidase activity
BBF96_02880	COG1283	sodium-dependent phosphate transmembrane transporter activity
BBF96_02885	COG1968	undecaprenyl-diphosphatase activity
BBF96_02895	COG1674	ftsk spoiiie
BBF96_02900	COG2188	Transcriptional regulator
BBF96_02930	COG1426	Protein conserved in bacteria
BBF96_02960	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BBF96_03025	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BBF96_03040	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BBF96_03060	COG0423	glycine-tRNA ligase activity
BBF96_03105	COG4152	abc transporter atp-binding protein
BBF96_03130	COG2814	Major facilitator Superfamily
BBF96_03160	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BBF96_03170	COG4942	peptidase
BBF96_03195	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBF96_03200	COG1012	belongs to the aldehyde dehydrogenase family
BBF96_03205	COG0840	transmembrane signaling receptor activity
BBF96_03215	COG3191	aminopeptidase activity
BBF96_03235	COG0582	viral genome integration into host DNA
BBF96_03305	COG1396	sequence-specific DNA binding
BBF96_03305	COG3800	Transcriptional regulator
BBF96_03365	COG0514	ATP-dependent DNA helicase (RecQ)
BBF96_03395	COG0629	single-stranded DNA binding
BBF96_03570	COG0860	N-Acetylmuramoyl-L-alanine amidase
BBF96_03625	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BBF96_03630	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BBF96_03670	COG0626	cystathionine gamma-synthase activity
BBF96_03675	COG1982	Orn Lys Arg decarboxylase major
BBF96_03680	COG1546	Belongs to the CinA family
BBF96_03680	COG1058	Belongs to the CinA family
BBF96_03685	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BBF96_03745	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BBF96_03750	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BBF96_03760	COG1418	mRNA catabolic process
BBF96_03770	COG1692	metallophosphoesterase
BBF96_03775	COG2359	stage V sporulation protein S
BBF96_03825	COG0601	transmembrane transport
BBF96_03830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBF96_03840	COG0840	transmembrane signaling receptor activity
BBF96_03875	COG3546	catalase activity
BBF96_03880	COG1252	NADH dehydrogenase
BBF96_03920	COG1573	uracil-dna glycosylase
BBF96_03930	COG0116	Belongs to the methyltransferase superfamily
BBF96_03935	COG1067	ATP-dependent peptidase activity
BBF96_03945	COG0864	Transcriptional regulator
BBF96_03950	COG0310	cobalt ion transport
BBF96_03965	COG1122	ATPase activity
BBF96_03970	COG2715	membrane protein required for spore maturation
BBF96_03975	COG0700	Nucleoside recognition
BBF96_03980	COG0613	PHP domain protein
BBF96_03990	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BBF96_03995	COG0811	peptide transport
BBF96_04000	COG0848	biopolymer transport protein
BBF96_04025	COG3773	Cell wall hydrolase
BBF96_04025	COG3409	Peptidoglycan-binding domain 1 protein
BBF96_04030	COG1278	Cold shock
BBF96_04040	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBF96_04045	COG0187	DNA topoisomerase II activity
BBF96_04050	COG2247	cell wall binding repeat
BBF96_04050	COG2385	sporulation resulting in formation of a cellular spore
BBF96_04055	COG2217	Heavy metal translocating P-type atpase
BBF96_04060	COG0640	Transcriptional regulator
BBF96_04065	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBF96_04080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BBF96_04085	COG2199	diguanylate cyclase activity
BBF96_04085	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BBF96_04090	COG0826	peptidase U32
BBF96_04120	COG1183	phosphatidylcholine synthase activity
BBF96_04125	COG0688	phosphatidylethanolamine metabolic process
BBF96_04150	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BBF96_04155	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BBF96_04160	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BBF96_04170	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBF96_04175	COG0534	Mate efflux family protein
BBF96_04180	COG4946	Tricorn protease homolog
BBF96_04180	COG1506	peptidase
BBF96_04180	COG0823	Involved in the tonB-independent uptake of proteins
BBF96_04185	COG3852	Histidine kinase
BBF96_04190	COG3973	AAA domain
BBF96_04205	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BBF96_04235	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BBF96_04260	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BBF96_04270	COG0511	ligase activity, forming carbon-carbon bonds
BBF96_04275	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BBF96_04280	COG2508	Transcriptional regulator
BBF96_04290	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BBF96_04300	COG1304	FMN binding
BBF96_04315	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BBF96_04320	COG0778	Nitroreductase
BBF96_04350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BBF96_04355	COG1410	methionine synthase
BBF96_04355	COG0646	methionine synthase
BBF96_04370	COG0778	Nitroreductase
BBF96_04380	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BBF96_04385	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BBF96_04390	COG0402	S-adenosylhomocysteine deaminase activity
BBF96_04395	COG2003	Belongs to the UPF0758 family
BBF96_04400	COG1309	transcriptional regulator
BBF96_04410	COG1566	PFAM secretion protein HlyD family protein
BBF96_04440	COG1132	(ABC) transporter
BBF96_04445	COG0445	tRNA wobble uridine modification
BBF96_04450	COG2304	oxidoreductase activity
BBF96_04455	COG1615	UPF0182 protein
BBF96_04460	COG0612	Peptidase, M16
BBF96_04465	COG0612	Peptidase, M16
BBF96_04470	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BBF96_04475	COG0477	Major facilitator Superfamily
BBF96_04485	COG0733	neurotransmitter:sodium symporter activity
BBF96_04495	COG1760	l-serine dehydratase
BBF96_04500	COG1760	l-serine dehydratase
BBF96_04505	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BBF96_04515	COG0546	phosphoglycolate phosphatase activity
BBF96_04520	COG0012	GTP binding
BBF96_04525	COG1307	EDD domain protein, DegV family
BBF96_04565	COG1846	Transcriptional regulator
BBF96_04575	COG3314	Sporulation integral membrane protein YlbJ
BBF96_04580	COG0165	Argininosuccinate lyase
BBF96_04590	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BBF96_04605	COG2226	methyltransferase
BBF96_04615	COG1752	Esterase of the alpha-beta hydrolase superfamily
BBF96_04620	COG3480	Lon protease (S16) C-terminal proteolytic domain
BBF96_04635	COG0280	phosphate acetyltransferase
BBF96_04640	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BBF96_04645	COG1399	metal-binding, possibly nucleic acid-binding protein
BBF96_04650	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BBF96_04655	COG2030	dehydratase
BBF96_04665	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BBF96_04670	COG2070	2-Nitropropane dioxygenase
BBF96_04675	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BBF96_04680	COG1028	Short-chain dehydrogenase reductase Sdr
BBF96_04685	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BBF96_04690	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BBF96_04705	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BBF96_04715	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BBF96_04715	COG0539	negative regulation of cytoplasmic translation
BBF96_04725	COG0860	N-Acetylmuramoyl-L-alanine amidase
BBF96_04750	COG0750	zinc metalloprotease
BBF96_04755	COG1160	GTP binding
BBF96_04760	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BBF96_04765	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BBF96_04770	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
BBF96_04780	COG0776	regulation of translation
BBF96_04785	COG0569	domain protein
BBF96_04800	COG0840	transmembrane signaling receptor activity
BBF96_04805	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
BBF96_04805	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BBF96_04810	COG0564	pseudouridine synthase activity
BBF96_04830	COG1363	Peptidase, m42
BBF96_04835	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BBF96_04865	COG1309	transcriptional regulator
BBF96_04880	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BBF96_04885	COG2002	toxin-antitoxin pair type II binding
BBF96_04890	COG0840	transmembrane signaling receptor activity
BBF96_04905	COG0113	porphobilinogen synthase activity
BBF96_04910	COG0464	growth
BBF96_04930	COG1923	regulation of RNA biosynthetic process
BBF96_04935	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BBF96_04940	COG0436	Aminotransferase
BBF96_04945	COG2031	fatty acid transporter
BBF96_04955	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BBF96_04960	COG1116	anion transmembrane transporter activity
BBF96_04965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBF96_04970	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BBF96_04995	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BBF96_05000	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BBF96_05005	COG0667	Aldo Keto reductase
BBF96_05015	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BBF96_05020	COG4770	biotin carboxylase activity
BBF96_05030	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BBF96_05035	COG0346	lactoylglutathione lyase activity
BBF96_05040	COG1703	isobutyryl-CoA mutase activity
BBF96_05045	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBF96_05045	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBF96_05060	COG1013	pyruvate-flavodoxin oxidoreductase activity
BBF96_05065	COG0674	pyruvate-flavodoxin oxidoreductase activity
BBF96_05065	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BBF96_05075	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BBF96_05080	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BBF96_05095	COG2814	Major facilitator Superfamily
BBF96_05100	COG1013	pyruvate-flavodoxin oxidoreductase activity
BBF96_05100	COG0674	pyruvate-flavodoxin oxidoreductase activity
BBF96_05100	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BBF96_05100	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BBF96_05105	COG0534	Mate efflux family protein
BBF96_05145	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BBF96_05150	COG1388	LysM domain
BBF96_05150	COG0791	NLP P60 protein
BBF96_05175	COG1363	Peptidase, m42
BBF96_05180	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BBF96_05185	COG2226	methyltransferase
BBF96_05200	COG3409	Peptidoglycan-binding domain 1 protein
BBF96_05200	COG3773	Cell wall hydrolase
BBF96_05220	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BBF96_05225	COG2086	electron transfer activity
BBF96_05240	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BBF96_05245	COG1085	galactose-1-phosphate uridylyltransferase
BBF96_05250	COG0438	transferase activity, transferring glycosyl groups
BBF96_05265	COG1653	transport
BBF96_05270	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBF96_05285	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BBF96_05290	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BBF96_05290	COG1796	DNA polymerase
BBF96_05295	COG0546	phosphoglycolate phosphatase activity
BBF96_05340	COG1131	(ABC) transporter
BBF96_05365	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BBF96_05370	COG0742	ribosomal rna small subunit methyltransferase
BBF96_05375	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BBF96_05380	COG1461	Dihydroxyacetone kinase
BBF96_05385	COG1302	Protein conserved in bacteria
BBF96_05390	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BBF96_05395	COG2116	formate transmembrane transporter activity
BBF96_05400	COG0746	molybdenum cofactor guanylyltransferase activity
BBF96_05420	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BBF96_05440	COG3118	belongs to the thioredoxin family
BBF96_05455	COG0281	malic enzyme
BBF96_05465	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BBF96_05495	COG0587	DNA-directed DNA polymerase activity
BBF96_05505	COG0312	modulator of DNA gyrase
BBF96_05530	COG2610	gluconate transmembrane transporter activity
BBF96_05535	COG1929	Belongs to the glycerate kinase type-1 family
BBF96_05540	COG3835	regulator
BBF96_05545	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BBF96_05550	COG0095	Lipoate-protein ligase
BBF96_05555	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BBF96_05565	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BBF96_05570	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BBF96_05575	COG0509	glycine decarboxylation via glycine cleavage system
BBF96_05580	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BBF96_05585	COG0823	Involved in the tonB-independent uptake of proteins
BBF96_05600	COG2006	4fe-4S ferredoxin, iron-sulfur binding domain protein
BBF96_05605	COG1113	amino acid transport
BBF96_05615	COG0501	Belongs to the peptidase M48B family
BBF96_05620	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BBF96_05625	COG1328	CTP reductase activity
BBF96_05630	COG0835	chemotaxis
BBF96_05645	COG1074	ATP-dependent DNA helicase activity
BBF96_05665	COG1363	Peptidase, m42
BBF96_05670	COG1404	Belongs to the peptidase S8 family
BBF96_05690	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BBF96_05695	COG1956	GAF domain-containing protein
BBF96_05705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBF96_05710	COG0601	transmembrane transport
BBF96_05715	COG0747	negative chemotaxis
BBF96_05725	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
BBF96_05740	COG0142	geranyltranstransferase activity
BBF96_05760	COG0298	carbon dioxide binding
BBF96_05765	COG0805	protein transport
BBF96_05770	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BBF96_05775	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BBF96_05800	COG2226	methyltransferase
BBF96_05815	COG3859	Proton-coupled thiamine transporter YuaJ
BBF96_05825	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BBF96_05825	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BBF96_05830	COG0307	riboflavin synthase, alpha
BBF96_05835	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BBF96_05835	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BBF96_05840	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BBF96_05845	COG1162	GTPase activity
BBF96_05850	COG0515	serine threonine protein kinase
BBF96_05850	COG2815	serine threonine protein kinase
BBF96_05855	COG0631	protein serine/threonine phosphatase activity
BBF96_05870	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BBF96_05870	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BBF96_05880	COG2738	Putative neutral zinc metallopeptidase
BBF96_05895	COG0242	peptide deformylase activity
BBF96_05900	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BBF96_05910	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBF96_05915	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BBF96_05920	COG1489	DNA binding
BBF96_05925	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BBF96_05935	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BBF96_05940	COG1758	RNA polymerase activity
BBF96_05945	COG0194	GDP metabolic process
BBF96_05955	COG1561	YicC-like family, N-terminal region
BBF96_05970	COG1136	(ABC) transporter
BBF96_05970	COG0577	efflux transmembrane transporter activity
BBF96_05980	COG1136	(ABC) transporter
BBF96_05980	COG0577	efflux transmembrane transporter activity
BBF96_06015	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BBF96_06020	COG1694	Mazg nucleotide pyrophosphohydrolase
BBF96_06030	COG0123	including yeast histone deacetylase and acetoin utilization protein
BBF96_06095	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BBF96_06100	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BBF96_06105	COG0167	dihydroorotate dehydrogenase activity
BBF96_06110	COG0543	2 iron, 2 sulfur cluster binding
BBF96_06115	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BBF96_06125	COG0284	orotidine-5'-phosphate decarboxylase activity
BBF96_06130	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BBF96_06135	COG0540	Belongs to the ATCase OTCase family
BBF96_06140	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BBF96_06145	COG0564	pseudouridine synthase activity
BBF96_06150	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BBF96_06155	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BBF96_06160	COG0778	Nitroreductase
BBF96_06180	COG2302	S4 RNA-binding domain
BBF96_06185	COG0762	integral membrane protein
BBF96_06190	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BBF96_06205	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BBF96_06210	COG1873	PFAM PRC-barrel domain
BBF96_06225	COG1191	sigma factor activity
BBF96_06230	COG1191	sigma factor activity
BBF96_06240	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BBF96_06255	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BBF96_06260	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BBF96_06265	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BBF96_06270	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BBF96_06275	COG0772	Belongs to the SEDS family
BBF96_06280	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BBF96_06290	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BBF96_06295	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BBF96_06300	COG0768	penicillin binding
BBF96_06310	COG0275	rRNA processing
BBF96_06315	COG2001	Belongs to the MraZ family
BBF96_06330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBF96_06335	COG0393	Putative heavy-metal-binding
BBF96_06345	COG1181	Belongs to the D-alanine--D-alanine ligase family
BBF96_06360	COG0402	S-adenosylhomocysteine deaminase activity
BBF96_06480	COG1775	2-hydroxyglutaryl-CoA dehydratase, D-component
BBF96_06515	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BBF96_06520	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BBF96_06540	COG1132	(ABC) transporter
BBF96_06550	COG1132	(ABC) transporter
BBF96_06555	COG1132	(ABC) transporter
BBF96_06560	COG1132	(ABC) transporter
BBF96_06585	COG0482	sulfurtransferase activity
BBF96_06590	COG0822	iron-sulfur transferase activity
BBF96_06600	COG1959	2 iron, 2 sulfur cluster binding
BBF96_06605	COG1739	Uncharacterized protein family UPF0029
BBF96_06610	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BBF96_06615	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BBF96_06625	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BBF96_06630	COG0124	histidyl-tRNA synthetase
BBF96_06635	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BBF96_06640	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BBF96_06645	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBF96_06650	COG1490	D-aminoacyl-tRNA deacylase activity
BBF96_06655	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BBF96_06660	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BBF96_06665	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BBF96_06665	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BBF96_06675	COG5416	Lipopolysaccharide assembly protein A domain
BBF96_06680	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BBF96_06685	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BBF96_06710	COG1131	(ABC) transporter
BBF96_06725	COG2197	response regulator
BBF96_06740	COG1862	Preprotein translocase
BBF96_06745	COG0343	queuine tRNA-ribosyltransferase activity
BBF96_06750	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BBF96_06760	COG2255	four-way junction helicase activity
BBF96_06765	COG0632	four-way junction helicase activity
BBF96_06770	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BBF96_06780	COG0217	transcriptional regulatory protein
BBF96_06830	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BBF96_06840	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBF96_06845	COG2313	pseudouridylate synthase activity
BBF96_06875	COG5002	protein histidine kinase activity
BBF96_06880	COG0745	RESPONSE REGULATOR receiver
BBF96_06895	COG0534	Mate efflux family protein
BBF96_06900	COG1937	Protein conserved in bacteria
BBF96_06915	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BBF96_06920	COG0358	DNA primase activity
BBF96_06930	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BBF96_06935	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BBF96_06935	COG0574	Belongs to the PEP-utilizing enzyme family
BBF96_06940	COG1494	fructose-1,6-bisphosphatase
BBF96_06945	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BBF96_06950	COG0517	IMP dehydrogenase activity
BBF96_06955	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BBF96_06965	COG1381	Involved in DNA repair and RecF pathway recombination
BBF96_06970	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BBF96_06975	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BBF96_06980	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BBF96_06985	COG0295	cytidine deaminase activity
BBF96_06990	COG1470	cell adhesion involved in biofilm formation
BBF96_07000	COG4536	flavin adenine dinucleotide binding
BBF96_07005	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BBF96_07010	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BBF96_07015	COG1480	7TM receptor with intracellular HD hydrolase
BBF96_07020	COG1702	phosphate starvation-inducible protein PhoH
BBF96_07035	COG2323	membrane
BBF96_07040	COG2323	membrane
BBF96_07050	COG4864	UPF0365 protein
BBF96_07055	COG1030	water channel activity
BBF96_07065	COG1595	DNA-templated transcription, initiation
BBF96_07070	COG1610	YqeY-like protein
BBF96_07080	COG0537	adenosine 5'-monophosphoramidase activity
BBF96_07085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBF96_07090	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BBF96_07110	COG0484	heat shock protein binding
BBF96_07115	COG0443	Heat shock 70 kDa protein
BBF96_07125	COG1420	regulation of RNA biosynthetic process
BBF96_07130	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BBF96_07155	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
BBF96_07165	COG0268	Binds directly to 16S ribosomal RNA
BBF96_07170	COG1466	dna polymerase III delta subunit
BBF96_07180	COG0798	PFAM Bile acid sodium symporter
BBF96_07210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BBF96_07225	COG0352	thiamine-phosphate diphosphorylase activity
BBF96_07235	COG0352	thiamine-phosphate diphosphorylase activity
BBF96_07240	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BBF96_07255	COG2104	thiamine diphosphate biosynthetic process
BBF96_07255	COG2022	thiamine diphosphate biosynthetic process
BBF96_07265	COG2333	competence protein COMEC
BBF96_07265	COG0658	competence protein
BBF96_07275	COG0799	negative regulation of ribosome biogenesis
BBF96_07280	COG1316	TRANSCRIPTIONal
BBF96_07285	COG1713	HD superfamily hydrolase involved in NAD metabolism
BBF96_07290	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BBF96_07315	COG0697	spore germination
BBF96_07330	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
BBF96_07380	COG1132	(ABC) transporter
BBF96_07385	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BBF96_07395	COG2855	membrane
BBF96_07400	COG0583	DNA-binding transcription factor activity
BBF96_07405	COG1405	negative regulation of cell septum assembly
BBF96_07405	COG3012	SEC-C Motif Domain Protein
BBF96_07445	COG2264	protein methyltransferase activity
BBF96_07455	COG1151	hydroxylamine reductase activity
BBF96_07520	COG0714	Associated with various cellular activities
BBF96_07525	COG0071	Belongs to the small heat shock protein (HSP20) family
BBF96_07545	COG0395	ABC-type sugar transport system, permease component
BBF96_07550	COG1175	transmembrane transport
BBF96_07570	COG2152	Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose
BBF96_07575	COG1609	Transcriptional regulator
BBF96_07585	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BBF96_07590	COG1473	amidohydrolase
BBF96_07610	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBF96_07615	COG0785	Cytochrome C biogenesis protein
BBF96_07640	COG3033	Beta-eliminating lyase
BBF96_07645	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BBF96_07650	COG2362	D-Aminopeptidase
BBF96_07655	COG2814	Major facilitator Superfamily
BBF96_07670	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BBF96_07675	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BBF96_07690	COG1530	ribonuclease E activity
BBF96_07715	COG0772	Belongs to the SEDS family
BBF96_07720	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BBF96_07725	COG2894	cell division
BBF96_07730	COG0850	regulation of cytokinetic process
BBF96_07735	COG0768	penicillin binding
BBF96_07745	COG1792	Involved in formation and maintenance of cell shape
BBF96_07750	COG1077	Cell shape determining protein MreB Mrl
BBF96_07755	COG2003	Belongs to the UPF0758 family
BBF96_07760	COG0424	maF-like protein
BBF96_07765	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BBF96_07770	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BBF96_07780	COG0181	hydroxymethylbilane synthase activity
BBF96_07785	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BBF96_07785	COG1648	precorrin-2 dehydrogenase activity
BBF96_07790	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BBF96_07800	COG2878	Part of a membrane complex involved in electron transport
BBF96_07800	COG1245	4Fe-4S binding domain
BBF96_07805	COG4657	Part of a membrane complex involved in electron transport
BBF96_07810	COG4660	Part of a membrane complex involved in electron transport
BBF96_07815	COG4659	FMN binding
BBF96_07820	COG4658	electron transport chain
BBF96_07825	COG4656	Part of a membrane complex involved in electron transport
BBF96_07835	COG0489	protein tyrosine kinase activity
BBF96_07845	COG2894	cell division
BBF96_07865	COG1342	Belongs to the UPF0251 family
BBF96_07870	COG5002	protein histidine kinase activity
BBF96_07885	COG0517	IMP dehydrogenase activity
BBF96_07885	COG0516	GMP reductase activity
BBF96_07900	COG0285	dihydrofolate synthase activity
BBF96_07905	COG1574	metal-dependent hydrolase with the TIM-barrel fold
BBF96_07920	COG0643	Histidine kinase
BBF96_07920	COG2198	Histidine kinase
BBF96_07925	COG0745	RESPONSE REGULATOR receiver
BBF96_07930	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BBF96_07940	COG2201	protein-glutamate methylesterase activity
BBF96_07945	COG0835	chemotaxis
BBF96_07955	COG3437	response regulator, receiver
BBF96_07965	COG0312	modulator of DNA gyrase
BBF96_07975	COG0251	oxidation-reduction process
BBF96_07980	COG0768	penicillin binding
BBF96_07985	COG4399	Belongs to the UPF0754 family
BBF96_07995	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
BBF96_07995	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BBF96_08015	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BBF96_08025	COG2226	methyltransferase
BBF96_08075	COG3328	transposase activity
BBF96_08110	COG0312	modulator of DNA gyrase
BBF96_08125	COG1032	radical SAM domain protein
BBF96_08145	COG0525	valine-tRNA ligase activity
BBF96_08155	COG0733	neurotransmitter:sodium symporter activity
BBF96_08170	COG1111	helicase
BBF96_08170	COG1205	dead DEAH box helicase
BBF96_08175	COG0583	DNA-binding transcription factor activity
BBF96_08200	COG0463	Glycosyl transferase, family 2
BBF96_08200	COG0457	Tetratricopeptide repeat
BBF96_08205	COG0463	Glycosyl transferase, family 2
BBF96_08210	COG0463	Glycosyl transferase, family 2
BBF96_08210	COG0457	Tetratricopeptide repeat
BBF96_08220	COG2226	methyltransferase
BBF96_08225	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBF96_08255	COG3547	Transposase (IS116 IS110 IS902 family)
BBF96_08260	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BBF96_08265	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BBF96_08270	COG0470	DNA polymerase III
BBF96_08270	COG1067	ATP-dependent peptidase activity
BBF96_08275	COG0438	transferase activity, transferring glycosyl groups
BBF96_08285	COG1609	Transcriptional regulator
BBF96_08290	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BBF96_08295	COG0740	serine-type endopeptidase activity
BBF96_08300	COG0544	peptidyl-prolyl cis-trans isomerase activity
BBF96_08315	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BBF96_08320	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BBF96_08330	COG2894	cell division
BBF96_08345	COG4608	Belongs to the ABC transporter superfamily
BBF96_08350	COG0444	Belongs to the ABC transporter superfamily
BBF96_08360	COG0601	transmembrane transport
BBF96_08365	COG0747	negative chemotaxis
BBF96_08380	COG3799	methylaspartate ammonia-lyase activity
BBF96_08385	COG4865	methylaspartate mutase activity
BBF96_08395	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBF96_08400	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BBF96_08405	COG1725	Transcriptional regulator
BBF96_08430	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBF96_08455	COG0714	Associated with various cellular activities
BBF96_08465	COG1132	(ABC) transporter
BBF96_08480	COG1027	Aspartate ammonia-lyase
BBF96_08485	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BBF96_08495	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
BBF96_08500	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BBF96_08505	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BBF96_08510	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BBF96_08520	COG1523	belongs to the glycosyl hydrolase 13 family
BBF96_08550	COG1592	Rubrerythrin
BBF96_08550	COG1773	rubredoxin
BBF96_08555	COG0840	transmembrane signaling receptor activity
BBF96_08555	COG5278	phosphoserine phosphatase activity
BBF96_08560	COG1686	Belongs to the peptidase S11 family
BBF96_08575	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BBF96_08580	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
BBF96_08590	COG0686	Belongs to the AlaDH PNT family
BBF96_08595	COG1300	Membrane
BBF96_08605	COG1379	DNA repair
BBF96_08620	COG2195	Cleaves the N-terminal amino acid of tripeptides
BBF96_08645	COG3426	butyrate kinase activity
BBF96_08655	COG0280	phosphate acetyltransferase
BBF96_08670	COG3290	protein histidine kinase activity
BBF96_08670	COG3829	transcription factor binding
BBF96_08675	COG0530	calcium, potassium:sodium antiporter activity
BBF96_08705	COG2746	aminoglycoside 3-N-acetyltransferase activity
BBF96_08710	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BBF96_08820	COG3547	Transposase (IS116 IS110 IS902 family)
BBF96_08830	COG3209	COG3209 Rhs family protein
BBF96_08960	COG3209	COG3209 Rhs family protein
BBF96_08995	COG1215	transferase activity, transferring glycosyl groups
BBF96_09010	COG0745	RESPONSE REGULATOR receiver
BBF96_09015	COG0750	zinc metalloprotease
BBF96_09020	COG0497	DNA recombination
BBF96_09025	COG1438	arginine binding
BBF96_09030	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BBF96_09035	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BBF96_09040	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BBF96_09055	COG1722	exodeoxyribonuclease VII activity
BBF96_09060	COG1570	exodeoxyribonuclease VII activity
BBF96_09065	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BBF96_09070	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BBF96_09070	COG0493	'glutamate synthase
BBF96_09090	COG1918	ferrous iron import across plasma membrane
BBF96_09090	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BBF96_09100	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BBF96_09145	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BBF96_09165	COG1302	Protein conserved in bacteria
BBF96_09170	COG0439	Biotin carboxylase
BBF96_09175	COG0511	ligase activity, forming carbon-carbon bonds
BBF96_09220	COG3854	ATPases associated with a variety of cellular activities
BBF96_09225	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BBF96_09230	COG1136	(ABC) transporter
BBF96_09240	COG1136	(ABC) transporter
BBF96_09240	COG0577	efflux transmembrane transporter activity
BBF96_09245	COG1136	(ABC) transporter
BBF96_09245	COG0577	efflux transmembrane transporter activity
BBF96_09260	COG0006	proline dipeptidase activity
BBF96_09265	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BBF96_09325	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BBF96_09330	COG2165	general secretion pathway protein
BBF96_09340	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BBF96_09355	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BBF96_09395	COG0735	belongs to the Fur family
BBF96_09410	COG2002	toxin-antitoxin pair type II binding
BBF96_09425	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BBF96_09435	COG0732	type I restriction modification DNA specificity domain
BBF96_09460	COG4555	ABC transporter
BBF96_09465	COG2252	PERMEase
BBF96_09470	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BBF96_09475	COG0167	dihydroorotate dehydrogenase activity
BBF96_09500	COG0402	S-adenosylhomocysteine deaminase activity
BBF96_09510	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BBF96_09515	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BBF96_09520	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBF96_09525	COG1396	sequence-specific DNA binding
BBF96_09530	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BBF96_09540	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BBF96_09545	COG1228	amidohydrolase
BBF96_09560	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BBF96_09575	COG3773	Cell wall hydrolase
BBF96_09575	COG3409	Peptidoglycan-binding domain 1 protein
BBF96_09580	COG2179	HAD superfamily (subfamily IIIA) phosphatase, TIGR01668
BBF96_09585	COG1191	sigma factor activity
BBF96_09600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BBF96_09610	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BBF96_09645	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BBF96_09650	COG0628	permease
BBF96_09675	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BBF96_09690	COG0330	HflC and HflK could
BBF96_09695	COG0330	HflC and HflK could
BBF96_09700	COG0495	leucyl-tRNA aminoacylation
BBF96_09710	COG2226	methyltransferase
BBF96_09715	COG0328	RNA-DNA hybrid ribonuclease activity
BBF96_09730	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BBF96_09750	COG1523	belongs to the glycosyl hydrolase 13 family
BBF96_09765	COG0849	cell division
BBF96_09780	COG0667	Aldo Keto reductase
BBF96_09785	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BBF96_09815	COG3706	GGDEF domain
BBF96_09815	COG0745	RESPONSE REGULATOR receiver
BBF96_09825	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BBF96_09830	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BBF96_09840	COG1193	negative regulation of DNA recombination
BBF96_09845	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BBF96_09845	COG1796	DNA polymerase
BBF96_09860	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BBF96_09885	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBF96_09885	COG0072	phenylalanine-tRNA ligase activity
BBF96_09890	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BBF96_09895	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBF96_09900	COG0569	domain protein
BBF96_09905	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BBF96_09910	COG0569	domain protein
BBF96_09915	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BBF96_09920	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BBF96_09925	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BBF96_09930	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BBF96_09940	COG1132	(ABC) transporter
BBF96_09945	COG1132	(ABC) transporter
BBF96_09955	COG4399	Belongs to the UPF0754 family
BBF96_09970	COG2333	competence protein COMEC
BBF96_09970	COG0658	competence protein
BBF96_10035	COG4608	Belongs to the ABC transporter superfamily
BBF96_10040	COG0444	Belongs to the ABC transporter superfamily
BBF96_10045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBF96_10050	COG0601	transmembrane transport
BBF96_10075	COG4608	Belongs to the ABC transporter superfamily
BBF96_10080	COG0444	Belongs to the ABC transporter superfamily
BBF96_10095	COG0747	negative chemotaxis
BBF96_10110	COG0312	modulator of DNA gyrase
BBF96_10115	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBF96_10120	COG0641	radical SAM
BBF96_10125	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BBF96_10135	COG1132	(ABC) transporter
BBF96_10140	COG1132	(ABC) transporter
BBF96_10145	COG4608	Belongs to the ABC transporter superfamily
BBF96_10150	COG0444	Belongs to the ABC transporter superfamily
BBF96_10165	COG0747	negative chemotaxis
BBF96_10170	COG1966	Carbon starvation protein
BBF96_10175	COG0741	lytic transglycosylase activity
BBF96_10175	COG1196	nuclear chromosome segregation
BBF96_10175	COG0739	heme binding
BBF96_10185	COG0237	dephospho-CoA kinase activity
BBF96_10190	COG1971	Probably functions as a manganese efflux pump
BBF96_10195	COG0488	(ABC) transporter
BBF96_10200	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BBF96_10240	COG0312	modulator of DNA gyrase
BBF96_10245	COG0312	modulator of DNA gyrase
BBF96_10275	COG0312	modulator of DNA gyrase
BBF96_10285	COG4555	ABC transporter
BBF96_10290	COG1032	radical SAM domain protein
BBF96_10320	COG0535	radical SAM domain protein
BBF96_10340	COG4555	ABC transporter
BBF96_10345	COG1879	ABC-type sugar transport system periplasmic component
BBF96_10350	COG1172	Belongs to the binding-protein-dependent transport system permease family
BBF96_10360	COG1869	D-ribose catabolic process
BBF96_10365	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBF96_10375	COG1301	dicarboxylic acid transport
BBF96_10385	COG1785	Belongs to the alkaline phosphatase family
BBF96_10395	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BBF96_10415	COG0395	ABC-type sugar transport system, permease component
BBF96_10425	COG2182	Extracellular solute-binding protein
BBF96_10435	COG3459	Glycosyltransferase 36 associated
BBF96_10440	COG1609	Transcriptional regulator
BBF96_10480	COG2176	DNA-directed DNA polymerase activity
BBF96_10490	COG1840	ABC-type Fe3 transport system, periplasmic component
BBF96_10495	COG1178	ABC-type Fe3 transport system permease component
BBF96_10500	COG3842	ATPase activity
BBF96_10505	COG0840	transmembrane signaling receptor activity
BBF96_10505	COG3290	protein histidine kinase activity
BBF96_10565	COG1595	DNA-templated transcription, initiation
BBF96_10575	COG1376	ErfK ybiS ycfS ynhG family protein
BBF96_10630	COG1473	amidohydrolase
BBF96_10635	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BBF96_10650	COG0395	ABC-type sugar transport system, permease component
BBF96_10655	COG1175	transmembrane transport
BBF96_10660	COG1653	transport
BBF96_10665	COG1609	Transcriptional regulator
BBF96_10670	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BBF96_10680	COG3679	Belongs to the UPF0342 family
BBF96_10690	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
BBF96_10705	COG0010	Belongs to the arginase family
BBF96_10710	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BBF96_10745	COG2959	enzyme of heme biosynthesis
BBF96_10750	COG3409	Peptidoglycan-binding domain 1 protein
BBF96_10750	COG3773	Cell wall hydrolase
BBF96_10765	COG1683	Conserved Protein
BBF96_10780	COG1959	2 iron, 2 sulfur cluster binding
BBF96_10785	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BBF96_10790	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BBF96_10810	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BBF96_10815	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BBF96_10820	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
BBF96_10830	COG1846	Transcriptional regulator
BBF96_10840	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBF96_10885	COG1706	bacterial-type flagellum-dependent cell motility
BBF96_10890	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BBF96_10905	COG4786	Flagellar basal body rod
BBF96_10930	COG1191	sigma factor activity
BBF96_10945	COG0455	bacterial-type flagellum organization
BBF96_10950	COG1419	protein localization to endoplasmic reticulum
BBF96_10955	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BBF96_10960	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BBF96_10965	COG1684	flagellar biosynthetic protein fliR
BBF96_10970	COG1987	bacterial-type flagellum assembly
BBF96_10975	COG1338	Plays a role in the flagellum-specific transport system
BBF96_10990	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BBF96_10990	COG1776	CheC inhibitor of MCP methylation
BBF96_10995	COG1868	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BBF96_11005	COG1360	Flagellar Motor Protein
BBF96_11015	COG1582	Flagellar protein (FlbD)
BBF96_11030	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BBF96_11045	COG2882	bacterial-type flagellum organization
BBF96_11050	COG1157	protein secretion by the type III secretion system
BBF96_11055	COG1317	bacterial-type flagellum organization
BBF96_11060	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BBF96_11065	COG1766	The M ring may be actively involved in energy transduction
BBF96_11070	COG1677	Flagellar hook-basal body complex protein FliE
BBF96_11080	COG1815	bacterial-type flagellum-dependent cell motility
BBF96_11085	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BBF96_11095	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BBF96_11100	COG2089	acid synthase
BBF96_11105	COG1083	cytidylyl-transferase
BBF96_11110	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BBF96_11115	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BBF96_11125	COG1516	flagellar protein fliS
BBF96_11145	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
BBF96_11150	COG1334	flagellar protein FlaG
BBF96_11155	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BBF96_11160	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
BBF96_11165	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BBF96_11175	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BBF96_11180	COG4786	Flagellar basal body rod
BBF96_11180	COG1256	bacterial-type flagellum assembly
BBF96_11200	COG0572	uridine kinase
BBF96_11225	COG1404	Belongs to the peptidase S8 family
BBF96_11235	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BBF96_11240	COG1482	cell wall glycoprotein biosynthetic process
BBF96_11265	COG0166	Belongs to the GPI family
BBF96_11270	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BBF96_11290	COG0728	peptidoglycan biosynthetic process
BBF96_11295	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BBF96_11300	COG3475	LICD family
BBF96_11315	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BBF96_11340	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BBF96_11370	COG3206	protein involved in exopolysaccharide biosynthesis
BBF96_11380	COG4372	Transposase
BBF96_11390	COG1137	ATPase activity
BBF96_11405	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BBF96_11415	COG1132	(ABC) transporter
BBF96_11420	COG1216	Glycosyl transferase, family 2
BBF96_11430	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BBF96_11435	COG3494	Protein of unknown function (DUF1009)
BBF96_11440	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BBF96_11445	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BBF96_11505	COG3328	transposase activity
BBF96_11515	COG3328	transposase activity
BBF96_11520	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BBF96_11540	COG1404	Belongs to the peptidase S8 family
BBF96_11560	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BBF96_11600	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BBF96_11605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BBF96_11620	COG1077	Cell shape determining protein MreB Mrl
BBF96_11625	COG1609	Transcriptional regulator
BBF96_11635	COG2385	sporulation resulting in formation of a cellular spore
BBF96_11640	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BBF96_11680	COG0840	transmembrane signaling receptor activity
BBF96_11690	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BBF96_11695	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BBF96_11700	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BBF96_11705	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BBF96_11710	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BBF96_11715	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BBF96_11725	COG0356	it plays a direct role in the translocation of protons across the membrane
BBF96_11745	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BBF96_11760	COG0698	ribose 5-phosphate isomerase
BBF96_11765	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BBF96_11770	COG1971	Probably functions as a manganese efflux pump
BBF96_11775	COG0009	L-threonylcarbamoyladenylate synthase
BBF96_11785	COG2890	protein-(glutamine-N5) methyltransferase activity
BBF96_11790	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BBF96_11795	COG3872	metal-dependent enzyme
BBF96_11800	COG1435	thymidine kinase activity
BBF96_11805	COG0840	transmembrane signaling receptor activity
BBF96_11810	COG0254	rRNA binding
BBF96_11815	COG0739	heme binding
BBF96_11820	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BBF96_11855	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BBF96_11855	COG0140	phosphoribosyl-ATP diphosphatase activity
BBF96_11860	COG0107	imidazoleglycerol-phosphate synthase activity
BBF96_11865	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BBF96_11870	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BBF96_11875	COG0131	Imidazoleglycerol-phosphate dehydratase
BBF96_11880	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BBF96_11890	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BBF96_11895	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BBF96_11900	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BBF96_11935	COG0840	transmembrane signaling receptor activity
BBF96_11990	COG0504	CTP synthase activity
BBF96_12020	COG3706	GGDEF domain
BBF96_12025	COG1024	Enoyl-CoA hydratase
BBF96_12030	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBF96_12035	COG0183	Belongs to the thiolase family
BBF96_12045	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BBF96_12050	COG3246	L-lysine catabolic process to acetate
BBF96_12055	COG1607	acyl-coa hydrolase
BBF96_12065	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BBF96_12070	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BBF96_12075	COG1193	negative regulation of DNA recombination
BBF96_12085	COG0604	alcohol dehydrogenase
BBF96_12125	COG1136	(ABC) transporter
BBF96_12125	COG0577	efflux transmembrane transporter activity
BBF96_12130	COG5002	protein histidine kinase activity
BBF96_12135	COG0745	RESPONSE REGULATOR receiver
BBF96_12150	COG1136	(ABC) transporter
BBF96_12150	COG0577	efflux transmembrane transporter activity
BBF96_12155	COG1136	(ABC) transporter
BBF96_12345	COG3829	transcription factor binding
BBF96_12345	COG3290	protein histidine kinase activity
BBF96_12355	COG2059	Chromate
BBF96_12385	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BBF96_12390	COG0076	glutamate decarboxylase activity
BBF96_12395	COG0667	Aldo Keto reductase
BBF96_12405	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BBF96_12410	COG2002	toxin-antitoxin pair type II binding
BBF96_12440	COG0697	spore germination
BBF96_12455	COG3546	catalase activity
BBF96_12470	COG1966	Carbon starvation protein
BBF96_12480	COG3275	phosphorelay sensor kinase activity
BBF96_12495	COG0531	amino acid
BBF96_12500	COG0697	spore germination
BBF96_12515	COG1454	alcohol dehydrogenase
BBF96_12530	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BBF96_12535	COG5609	conserved protein (DUF2294)
BBF96_12545	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BBF96_12560	COG1454	alcohol dehydrogenase
BBF96_12590	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BBF96_12605	COG1592	Rubrerythrin
BBF96_12610	COG3706	GGDEF domain
BBF96_12615	COG2244	polysaccharide biosynthetic process
BBF96_12630	COG0626	cystathionine gamma-synthase activity
BBF96_12635	COG1988	membrane-bound metal-dependent
BBF96_12645	COG1691	(AIR) carboxylase
BBF96_12650	COG1606	tRNA processing
BBF96_12665	COG0189	ligase activity
BBF96_12695	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BBF96_12700	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BBF96_12705	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BBF96_12710	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BBF96_12715	COG1605	Chorismate mutase
BBF96_12715	COG0077	Prephenate dehydratase
BBF96_12720	COG0287	Prephenate dehydrogenase
BBF96_12725	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BBF96_12730	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BBF96_12735	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BBF96_12740	COG0018	arginyl-trna synthetase
BBF96_12765	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BBF96_12775	COG5002	protein histidine kinase activity
BBF96_12790	COG1404	Belongs to the peptidase S8 family
BBF96_12805	COG0697	spore germination
BBF96_12830	COG2226	methyltransferase
BBF96_12845	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BBF96_12855	COG1131	(ABC) transporter
BBF96_12895	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BBF96_12905	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BBF96_12910	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BBF96_12915	COG2201	protein-glutamate methylesterase activity
BBF96_12920	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BBF96_12930	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BBF96_12935	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
BBF96_12945	COG1266	CAAX protease self-immunity
BBF96_12950	COG5002	protein histidine kinase activity
BBF96_12955	COG0745	RESPONSE REGULATOR receiver
BBF96_12975	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BBF96_12980	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BBF96_12985	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BBF96_12990	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BBF96_12995	COG0047	phosphoribosylformylglycinamidine synthase activity
BBF96_13000	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BBF96_13010	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BBF96_13060	COG0584	glycerophosphoryl diester phosphodiesterase
BBF96_13070	COG1752	Esterase of the alpha-beta hydrolase superfamily
BBF96_13075	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BBF96_13080	COG0151	Belongs to the GarS family
BBF96_13085	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BBF96_13090	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BBF96_13095	COG1605	Chorismate mutase
BBF96_13095	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BBF96_13115	COG1032	radical SAM domain protein
BBF96_13145	COG1484	DNA-dependent DNA replication
BBF96_13150	COG0305	Participates in initiation and elongation during chromosome replication
BBF96_13165	COG1067	ATP-dependent peptidase activity
BBF96_13165	COG0470	DNA polymerase III
BBF96_13170	COG0359	binds to the 23S rRNA
BBF96_13185	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BBF96_13190	COG0629	single-stranded DNA binding
BBF96_13195	COG0360	Binds together with S18 to 16S ribosomal RNA
BBF96_13205	COG4555	ABC transporter
BBF96_13215	COG0012	GTP binding
BBF96_13220	COG4481	Protein conserved in bacteria
BBF96_13225	COG0668	transmembrane transport
BBF96_13255	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BBF96_13260	COG3949	Membrane
BBF96_13275	COG1597	lipid kinase activity
BBF96_13285	COG0739	heme binding
BBF96_13310	COG0569	domain protein
BBF96_13315	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BBF96_13320	COG1475	DNA binding
BBF96_13325	COG1192	Involved in chromosome partitioning
BBF96_13335	COG0357	Ribosomal RNA small subunit methyltransferase G
BBF96_13340	COG0445	tRNA wobble uridine modification
BBF96_13345	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BBF96_13350	COG1847	R3H domain protein
BBF96_13355	COG0706	membrane insertase activity
BBF96_13360	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BBF96_13370	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BBF96_13375	COG0592	DNA-directed DNA polymerase activity
BBF96_13385	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BBF96_13395	COG0187	DNA topoisomerase II activity
BBF96_13400	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBF96_13500	COG2814	Major facilitator Superfamily
BBF96_13525	COG3328	transposase activity
BBF96_13550	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBF96_13585	COG5012	cobalamin binding
BBF96_13605	COG0604	alcohol dehydrogenase
BBF96_13610	COG0647	UMP catabolic process
BBF96_13620	COG3829	transcription factor binding
BBF96_13625	COG0616	signal peptide processing
BBF96_13635	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BBF96_13655	COG0420	3'-5' exonuclease activity
BBF96_13665	COG3852	Histidine kinase
BBF96_13670	COG0860	N-Acetylmuramoyl-L-alanine amidase
BBF96_13685	COG0590	tRNA wobble adenosine to inosine editing
BBF96_13695	COG1051	belongs to the nudix hydrolase family
BBF96_13735	COG4555	ABC transporter
BBF96_13780	COG3339	Conserved Protein
BBF96_13790	COG2226	methyltransferase
BBF96_13850	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BBF96_13880	COG4555	ABC transporter
BBF96_13885	COG1342	Belongs to the UPF0251 family
BBF96_13905	COG1131	(ABC) transporter
BBF96_13910	COG0535	radical SAM domain protein
BBF96_13925	COG1132	(ABC) transporter
BBF96_13935	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BBF96_13940	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BBF96_13945	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BBF96_13960	COG1809	phosphosulfolactate synthase activity
BBF96_13965	COG2045	Belongs to the ComB family
BBF96_13970	COG2707	UPF0756 membrane protein
BBF96_13985	COG2855	membrane
BBF96_13990	COG0840	transmembrane signaling receptor activity
BBF96_14020	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BBF96_14025	COG1144	Oxidoreductase
BBF96_14030	COG0674	pyruvate-flavodoxin oxidoreductase activity
BBF96_14035	COG1013	pyruvate-flavodoxin oxidoreductase activity
BBF96_14050	COG0840	transmembrane signaling receptor activity
BBF96_14050	COG3290	protein histidine kinase activity
BBF96_14060	COG0517	IMP dehydrogenase activity
BBF96_14060	COG0516	GMP reductase activity
BBF96_14065	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BBF96_14075	COG3870	Protein conserved in bacteria
BBF96_14080	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BBF96_14085	COG1774	PSP1 C-terminal conserved region
BBF96_14095	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BBF96_14100	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BBF96_14105	COG2002	toxin-antitoxin pair type II binding
BBF96_14110	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBF96_14110	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBF96_14130	COG0084	hydrolase, TatD family'
BBF96_14145	COG4585	Histidine kinase
BBF96_14150	COG2197	response regulator
BBF96_14155	COG2197	response regulator
BBF96_14175	COG3858	chitin binding
BBF96_14185	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BBF96_14215	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BBF96_14230	COG4466	Protein conserved in bacteria
BBF96_14250	COG1215	transferase activity, transferring glycosyl groups
BBF96_14265	COG0745	RESPONSE REGULATOR receiver
BBF96_14270	COG5002	protein histidine kinase activity
BBF96_14275	COG0037	tRNA processing
BBF96_14285	COG0561	phosphatase activity
BBF96_14300	COG1175	transmembrane transport
BBF96_14305	COG0395	ABC-type sugar transport system, permease component
BBF96_14310	COG1554	hydrolase, family 65, central catalytic
BBF96_14340	COG0535	radical SAM domain protein
BBF96_14345	COG4152	abc transporter atp-binding protein
BBF96_14355	COG0312	modulator of DNA gyrase
BBF96_14370	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BBF96_14375	COG0573	inorganic phosphate transmembrane transporter activity
BBF96_14385	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BBF96_14390	COG0704	Plays a role in the regulation of phosphate uptake
BBF96_14395	COG0747	negative chemotaxis
BBF96_14425	COG3181	Tripartite tricarboxylate transporter family receptor
BBF96_14440	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBF96_14445	COG1414	Transcriptional regulator
BBF96_14490	COG0038	chloride channel
BBF96_14495	COG1980	fructose-bisphosphate aldolase activity
BBF96_14500	COG0017	Asparaginyl-tRNA synthetase
BBF96_14510	COG0301	tRNA thio-modification
BBF96_14515	COG0840	transmembrane signaling receptor activity
BBF96_14515	COG3290	protein histidine kinase activity
BBF96_14530	COG0840	transmembrane signaling receptor activity
BBF96_14530	COG3290	protein histidine kinase activity
BBF96_14540	COG1376	ErfK ybiS ycfS ynhG family protein
BBF96_14545	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BBF96_14555	COG1459	type II secretion system
BBF96_14560	COG4968	Prepilin-type N-terminal cleavage methylation domain
BBF96_14650	COG2226	methyltransferase
BBF96_14660	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BBF96_14695	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BBF96_14705	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BBF96_14720	COG1131	(ABC) transporter
BBF96_14750	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BBF96_14825	COG1797	cobyrinic acid a,c-diamide synthase activity
BBF96_14835	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BBF96_14840	COG2109	Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids
BBF96_14850	COG0789	Transcriptional regulator
BBF96_14855	COG0174	glutamine synthetase
BBF96_14865	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BBF96_14880	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BBF96_14885	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BBF96_14890	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BBF96_14895	COG0193	aminoacyl-tRNA hydrolase activity
BBF96_14905	COG1842	Phage shock protein A
BBF96_14925	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BBF96_14940	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BBF96_14945	COG2002	toxin-antitoxin pair type II binding
BBF96_14950	COG2244	polysaccharide biosynthetic process
BBF96_14955	COG3956	TIGRFAM MazG family protein
BBF96_14965	COG1686	Belongs to the peptidase S11 family
BBF96_14970	COG2385	sporulation resulting in formation of a cellular spore
BBF96_15065	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBF96_15070	COG1120	ATPase activity
BBF96_15090	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BBF96_15090	COG3608	succinylglutamate desuccinylase aspartoacylase
BBF96_15100	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BBF96_15105	COG2068	MobA-Related Protein
BBF96_15110	COG3608	succinylglutamate desuccinylase aspartoacylase
BBF96_15110	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BBF96_15130	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BBF96_15135	COG0549	Belongs to the carbamate kinase family
BBF96_15145	COG3842	ATPase activity
BBF96_15160	COG3706	GGDEF domain
BBF96_15185	COG2183	response to ionizing radiation
BBF96_15200	COG1131	(ABC) transporter
BBF96_15205	COG2208	phosphoserine phosphatase activity
BBF96_15210	COG0037	tRNA processing
BBF96_15220	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BBF96_15230	COG2986	histidine ammonia-lyase
BBF96_15235	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BBF96_15245	COG1228	amidohydrolase
BBF96_15250	COG3404	Formiminotransferase-cyclodeaminase
BBF96_15255	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BBF96_15260	COG0432	Pfam Uncharacterised protein family UPF0047
BBF96_15280	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BBF96_15285	COG1027	Aspartate ammonia-lyase
BBF96_15305	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BBF96_15310	COG0825	malonyl-CoA metabolic process
BBF96_15315	COG0205	6-phosphofructokinase activity
BBF96_15325	COG3030	protein affecting phage T7 exclusion by the F plasmid
BBF96_15345	COG1196	nuclear chromosome segregation
BBF96_15345	COG0741	lytic transglycosylase activity
BBF96_15345	COG0739	heme binding
BBF96_15355	COG3829	transcription factor binding
BBF96_15355	COG3290	protein histidine kinase activity
BBF96_15365	COG5275	peptidyl-tyrosine sulfation
BBF96_15365	COG0252	asparaginase activity
BBF96_15375	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BBF96_15380	COG1978	Selenoprotein B, glycine betaine sarcosine D-proline reductase family
BBF96_15385	COG0252	asparaginase activity
BBF96_15385	COG5275	peptidyl-tyrosine sulfation
BBF96_15390	COG5275	peptidyl-tyrosine sulfation
BBF96_15390	COG0252	asparaginase activity
BBF96_15415	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BBF96_15430	COG1131	(ABC) transporter
BBF96_15445	COG2087	Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate
BBF96_15455	COG0406	alpha-ribazole phosphatase activity
BBF96_15460	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BBF96_15470	COG0745	RESPONSE REGULATOR receiver
BBF96_15475	COG5002	protein histidine kinase activity
BBF96_15480	COG2239	Acts as a magnesium transporter
BBF96_15490	COG0019	diaminopimelate decarboxylase activity
BBF96_15515	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BBF96_15520	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BBF96_15525	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BBF96_15530	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BBF96_15535	COG0157	Belongs to the NadC ModD family
BBF96_15585	COG1268	BioY protein
BBF96_15590	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BBF96_15620	COG5322	oxidoreductase activity
BBF96_15620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BBF96_15630	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BBF96_15655	COG4555	ABC transporter
BBF96_15685	COG3880	PFAM UvrB UvrC protein
BBF96_15690	COG3869	Catalyzes the specific phosphorylation of arginine residues in
BBF96_15695	COG0542	response to heat
BBF96_15700	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BBF96_15705	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BBF96_15715	COG1329	Transcriptional regulator
BBF96_15720	COG4956	integral membrane protein (PIN domain superfamily)
BBF96_15725	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BBF96_15730	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BBF96_15745	COG1757	Na H antiporter
BBF96_15755	COG4086	secreted protein
BBF96_15760	COG1045	serine acetyltransferase
BBF96_15765	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
BBF96_15775	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBF96_15785	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BBF96_15790	COG2813	Specifically methylates the guanine in position
BBF96_15795	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BBF96_15800	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BBF96_15805	COG0250	Participates in transcription elongation, termination and antitermination
BBF96_15810	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BBF96_15815	COG0081	regulation of translation
BBF96_15820	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BBF96_15835	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BBF96_15840	COG1358	cellular component organization or biogenesis
BBF96_15845	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BBF96_15850	COG0049	tRNA binding
BBF96_15855	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BBF96_15860	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BBF96_15865	COG0051	transcription antitermination factor activity, RNA binding
BBF96_15870	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BBF96_15875	COG0088	Forms part of the polypeptide exit tunnel
BBF96_15880	COG0089	rRNA binding
BBF96_15885	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BBF96_15890	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BBF96_15895	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BBF96_15900	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BBF96_15905	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BBF96_15910	COG0255	Belongs to the universal ribosomal protein uL29 family
BBF96_15915	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BBF96_15920	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BBF96_15925	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BBF96_15930	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BBF96_15935	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BBF96_15940	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BBF96_15945	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BBF96_15950	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BBF96_15955	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BBF96_15960	COG0200	Binds to the 23S rRNA
BBF96_15970	COG0563	adenylate kinase activity
BBF96_15985	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BBF96_15990	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BBF96_15995	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BBF96_16000	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BBF96_16005	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BBF96_16010	COG0202	RNA polymerase activity
BBF96_16015	COG0203	ribosomal protein L17
BBF96_16020	COG1122	ATPase activity
BBF96_16030	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BBF96_16040	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BBF96_16045	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)