locus-tag	class	description
FRZ59_00020	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FRZ59_00075	ENOG4105HA9	of methanol dehydrogenase type
FRZ59_00080	ENOG4105IIU	Aminopeptidase
FRZ59_00095	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FRZ59_00100	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
FRZ59_00110	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
FRZ59_00115	ENOG4108Y6J	UPF0403 protein
FRZ59_00125	ENOG4105EEI	dihydropteroate synthase
FRZ59_00140	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
FRZ59_00145	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
FRZ59_00155	ENOG4108Z9K	Osmotically inducible protein
FRZ59_00165	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FRZ59_00170	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
FRZ59_00175	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
FRZ59_00180	ENOG4108IUZ	ABC transporter
FRZ59_00195	ENOG4105DU1	integral membrane protein, terc
FRZ59_00205	ENOG4105C28	cystathionine
FRZ59_00265	ENOG4108UXE	Protein tyrosine phosphatase
FRZ59_00295	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_00305	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
FRZ59_00335	ENOG4105CTQ	phosphohexokinase
FRZ59_00345	ENOG4107RE3	peptidase, S41
FRZ59_00355	ENOG4105CUJ	penicillin amidase
FRZ59_00410	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
FRZ59_00420	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FRZ59_00430	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
FRZ59_00460	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
FRZ59_00465	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
FRZ59_00475	ENOG4105DFU	Cell wall formation (By similarity)
FRZ59_00490	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
FRZ59_00495	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FRZ59_00500	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
FRZ59_00505	ENOG4105CJN	penicillin-binding protein
FRZ59_00520	ENOG4107YM1	mraZ protein
FRZ59_00525	ENOG4108RFI	Molecular chaperone that interacts specifically with outer membrane proteins, thus maintaining the solubility of early folding intermediates during passage through the periplasm (By similarity)
FRZ59_00545	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
FRZ59_00555	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
FRZ59_00565	ENOG4106HB6	Alpha beta hydrolase
FRZ59_00580	ENOG4105EMU	Dehydrogenase
FRZ59_00590	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FRZ59_00605	ENOG4107RBB	ABC transporter, permease
FRZ59_00615	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
FRZ59_00620	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
FRZ59_00635	ENOG4105CUB	amino acid
FRZ59_00675	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
FRZ59_00680	ENOG41061JJ	Peptidase family M23
FRZ59_00685	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FRZ59_00710	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
FRZ59_00715	ENOG4105EMN	RNA polymerase sigma factor
FRZ59_00730	ENOG4108R7K	Metal Dependent Phosphohydrolase
FRZ59_00740	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
FRZ59_00780	ENOG4105C6K	Malic enzyme
FRZ59_00785	ENOG4105E9H	Lytic Murein transglycosylase
FRZ59_00790	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
FRZ59_00795	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
FRZ59_00805	ENOG4105DR5	peptidase
FRZ59_00820	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
FRZ59_00830	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
FRZ59_00835	ENOG4107Y3Y	amidohydrolase
FRZ59_00840	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
FRZ59_00855	ENOG4105CKK	Glycosyl transferase, family 2
FRZ59_00865	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
FRZ59_00870	ENOG4105DA5	(ABC) transporter
FRZ59_00885	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
FRZ59_00895	ENOG4105MIR	Phenylalanine 4-monooxygenase
FRZ59_00900	ENOG4105UYK	outer membrane protein a
FRZ59_00905	ENOG4105EMU	Dehydrogenase
FRZ59_00915	ENOG4105EW6	flavin reductase domain protein, FMN-binding
FRZ59_00930	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
FRZ59_00945	ENOG4105FTV	AraC Family Transcriptional Regulator
FRZ59_00950	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FRZ59_00955	ENOG4107RJ1	sodium solute
FRZ59_00965	ENOG4105DC1	bifunctional purine biosynthesis protein purh
FRZ59_00970	ENOG4105DFF	Rod shape-determining protein mreb
FRZ59_00990	ENOG4105CNI	cell division protein FtsW
FRZ59_01000	ENOG4105Y3U	Transglycosylase-associated protein
FRZ59_01005	ENOG4105MGM	doxx family
FRZ59_01035	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_01040	ENOG4107TYA	transient receptor potential locus
FRZ59_01045	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
FRZ59_01050	ENOG4105DF5	DNA topoisomerase IV, subunit A
FRZ59_01060	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
FRZ59_01095	ENOG4105CSM	endonuclease III
FRZ59_01100	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
FRZ59_01115	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
FRZ59_01155	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FRZ59_01165	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
FRZ59_01200	ENOG4108VAC	response regulator
FRZ59_01220	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_01235	ENOG4105D05	Receptor
FRZ59_01260	ENOG4105EDR	glucose galactose transporter
FRZ59_01280	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_01295	ENOG4105C01	Dihydroxy-acid dehydratase
FRZ59_01310	ENOG4105CAQ	asparagine synthetase
FRZ59_01315	ENOG4105CXT	aspartate transcarbamylase
FRZ59_01335	ENOG4107QR9	Iron-sulfur cluster binding protein
FRZ59_01340	ENOG4107SET	aldo keto reductase
FRZ59_01385	ENOG4105CPP	Dehydrogenase, E1 component
FRZ59_01405	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FRZ59_01410	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
FRZ59_01445	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_01465	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
FRZ59_01485	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FRZ59_01495	ENOG4108VA3	3-hexulose-6-phosphate synthase
FRZ59_01500	ENOG4105CBG	Sulfatase
FRZ59_01520	ENOG4105E6M	Sulphatase-modifying factor protein
FRZ59_01540	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
FRZ59_01550	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
FRZ59_01570	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
FRZ59_01575	ENOG4105D06	uba thif-type nad fad binding protein
FRZ59_01585	ENOG4107QZF	nitrite reductase NADPH large subunit
FRZ59_01590	ENOG4107QZF	nitrite reductase NADPH large subunit
FRZ59_01600	ENOG4105BZU	Histidine kinase
FRZ59_01605	ENOG4105WH1	Two component transcriptional regulator luxr family
FRZ59_01610	ENOG4107RNU	major facilitator superfamily MFS_1
FRZ59_01625	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
FRZ59_01630	ENOG4108JQC	penicillin-binding protein 1A
FRZ59_01665	ENOG4105VHG	atp synthase
FRZ59_01670	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
FRZ59_01675	ENOG4107Z4P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FRZ59_01680	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
FRZ59_01685	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
FRZ59_01725	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
FRZ59_01730	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
FRZ59_01735	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
FRZ59_01750	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
FRZ59_01755	ENOG4105SCY	DNAK suppressor
FRZ59_01760	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FRZ59_01770	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
FRZ59_01780	ENOG4105NAE	bifunctional deaminase-reductase domain protein
FRZ59_01790	ENOG4105K64	Glycosyl transferase, family 2
FRZ59_01795	ENOG4108SHN	Glycosyl transferase, family 2
FRZ59_01805	ENOG4105K64	Glycosyl transferase, family 2
FRZ59_01815	ENOG4105EY8	ABC transporter
FRZ59_01840	ENOG4107S2Z	UPF0761 membrane protein
FRZ59_01865	ENOG4105NXH	GreA GreB family elongation factor
FRZ59_01875	ENOG4105EDR	glucose galactose transporter
FRZ59_01890	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
FRZ59_01935	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FRZ59_01940	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
FRZ59_01955	ENOG4105CNT	hydrolase family 2
FRZ59_01970	ENOG4107TTA	Xylose isomerase domain protein TIM barrel
FRZ59_02000	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_02015	ENOG41061MV	Arylsulfatase
FRZ59_02040	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FRZ59_02050	ENOG4105ETE	Transcriptional regulator (LacI family
FRZ59_02070	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_02085	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
FRZ59_02090	ENOG4105CTU	Proline racemase
FRZ59_02095	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FRZ59_02110	ENOG4107TTA	Xylose isomerase domain protein TIM barrel
FRZ59_02115	ENOG4105FTV	AraC Family Transcriptional Regulator
FRZ59_02125	ENOG4105EGD	dinuclear metal center protein, YbgI family
FRZ59_02140	ENOG4108JA2	transcriptioN-repair coupling factor
FRZ59_02145	ENOG4105K4H	Nlp p60 protein
FRZ59_02175	ENOG4105D1H	recombination factor protein RarA
FRZ59_02190	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
FRZ59_02205	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FRZ59_02210	ENOG4105BZU	Histidine kinase
FRZ59_02230	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
FRZ59_02250	ENOG4108SJC	Membrane
FRZ59_02270	ENOG4105CCU	oxidase (Subunit III)
FRZ59_02275	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
FRZ59_02285	ENOG4105BZ9	Cytochrome C oxidase, subunit I
FRZ59_02315	ENOG4107SFQ	iron-sulfur binding
FRZ59_02360	ENOG4105VFF	UPF0102 protein
FRZ59_02365	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
FRZ59_02375	ENOG4107S85	alpha-2-macroglobulin domain protein
FRZ59_02385	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FRZ59_02390	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FRZ59_02410	ENOG4107WT5	transcriptional regulator (NifA
FRZ59_02415	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FRZ59_02440	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FRZ59_02445	ENOG4107QP8	phosphohexose isomerase
FRZ59_02450	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FRZ59_02460	ENOG4105E98	transcriptional regulator DeoR family
FRZ59_02480	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_02485	ENOG4105CSC	Glucose uptake protein
FRZ59_02505	ENOG4107Z6W	Protein CrcB homolog
FRZ59_02510	ENOG4108JQ1	Dehydrogenase
FRZ59_02525	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
FRZ59_02540	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FRZ59_02545	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FRZ59_02550	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
FRZ59_02565	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FRZ59_02570	ENOG4105C12	Phosphoribosylglycinamide synthetase
FRZ59_02620	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FRZ59_02625	ENOG4105BZU	Histidine kinase
FRZ59_02635	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
FRZ59_02640	ENOG4105BZP	glycoside hydrolase 15-related
FRZ59_02650	ENOG4105T16	Transcriptional regulator (AraC family)
FRZ59_02665	ENOG4108JJA	ABC, transporter
FRZ59_02690	ENOG4105ECQ	AraC Family Transcriptional Regulator
FRZ59_02695	ENOG4105CYF	SMP-30 gluconolaconase LRE domain protein
FRZ59_02705	ENOG4105E08	Glycoside hydrolase, family 9
FRZ59_02730	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
FRZ59_02740	ENOG4105CK5	oxidoreductase
FRZ59_02765	ENOG4105FDP	GntR family transcriptional regulator
FRZ59_02780	ENOG41090JD	Blue (Type 1) copper domain protein
FRZ59_02800	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_02820	ENOG4105CK5	oxidoreductase
FRZ59_02845	ENOG4105C9F	isomerase
FRZ59_02865	ENOG4105D8V	Glucose sorbosone dehydrogenase
FRZ59_02870	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FRZ59_02875	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FRZ59_02880	ENOG4105CHV	Transcription elongation factor NusA
FRZ59_02885	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
FRZ59_02905	ENOG4105C1G	acyl-Coa dehydrogenase
FRZ59_02910	ENOG4105CHM	Aminotransferase
FRZ59_02920	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
FRZ59_02930	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
FRZ59_02935	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
FRZ59_02940	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
FRZ59_02950	ENOG4105ETE	Transcriptional regulator (LacI family
FRZ59_02955	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
FRZ59_02960	ENOG4108Z6B	deaminase
FRZ59_02970	ENOG4108Z7R	Chaperone CsaA
FRZ59_02975	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
FRZ59_02980	ENOG4108RMU	ferritin dps family protein
FRZ59_03000	ENOG4105CGK	Exodeoxyribonuclease III
FRZ59_03010	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
FRZ59_03015	ENOG4105D9R	oxidoreductase
FRZ59_03020	ENOG4107XGZ	Hydrolase
FRZ59_03035	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
FRZ59_03090	ENOG4105DA5	(ABC) transporter
FRZ59_03095	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FRZ59_03100	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FRZ59_03105	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FRZ59_03115	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FRZ59_03120	ENOG4105K8N	protein family UPF0079, ATPase
FRZ59_03125	ENOG4105DCF	alanine dehydrogenase
FRZ59_03130	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
FRZ59_03135	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FRZ59_03140	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
FRZ59_03145	ENOG4105DZP	Membrane-associated zinc metalloprotease
FRZ59_03155	ENOG4105CP2	von willebrand factor, type a
FRZ59_03190	ENOG4105W2Z	cytochrome C, class I
FRZ59_03205	ENOG4105EMN	RNA polymerase sigma factor
FRZ59_03220	ENOG4105CBG	Sulfatase
FRZ59_03230	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_03235	ENOG4105D7A	ATP-binding protein
FRZ59_03300	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
FRZ59_03305	ENOG4108JJA	ABC, transporter
FRZ59_03350	ENOG4105EKQ	RNA-directed DNA polymerase
FRZ59_03370	ENOG4108QD1	Membrane
FRZ59_03390	ENOG4105BZU	Histidine kinase
FRZ59_03395	ENOG4105WH1	Two component transcriptional regulator luxr family
FRZ59_03400	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
FRZ59_03415	ENOG4105WH1	Two component transcriptional regulator luxr family
FRZ59_03430	ENOG4105DKQ	ROK family
FRZ59_03440	ENOG4106QJ6	Integrase catalytic subunit
FRZ59_03445	ENOG4105EN2	IstB domain-containing protein ATP-binding protein
FRZ59_03465	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_03470	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FRZ59_03485	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
FRZ59_03490	ENOG4107S7E	1-acyl-sn-glycerol-3-phosphate acyltransferase
FRZ59_03510	ENOG4105YHG	TonB family
FRZ59_03520	ENOG4107VAM	peptidase, m28
FRZ59_03540	ENOG4105E33	succinate dehydrogenase
FRZ59_03560	ENOG4105E2X	shikimate dehydrogenase
FRZ59_03575	ENOG4105D60	lipoprotein releasing system transmembrane protein
FRZ59_03590	ENOG4105E63	Pfam:DUF178
FRZ59_03605	ENOG4105EUJ	GTP cyclohydrolase i
FRZ59_03625	ENOG4107RAN	Peptidase, M16
FRZ59_03635	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
FRZ59_03640	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
FRZ59_03645	ENOG4105E98	transcriptional regulator DeoR family
FRZ59_03650	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_03660	ENOG4105EHZ	conserved protein UCP016719
FRZ59_03665	ENOG4108VAC	response regulator
FRZ59_03670	ENOG4108HRK	Histidine kinase
FRZ59_03695	ENOG4107TT5	NLP P60 protein
FRZ59_03700	ENOG4105D64	Mechanosensitive ion channel
FRZ59_03710	ENOG4108FN7	Aldo keto reductase
FRZ59_03720	ENOG4105CBG	Sulfatase
FRZ59_03730	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
FRZ59_03760	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
FRZ59_03765	ENOG4105CGZ	zinc metallopeptidase
FRZ59_03775	ENOG4105DJ2	Major Facilitator Superfamily
FRZ59_03795	ENOG4105CN1	protease
FRZ59_03805	ENOG4108J9Q	DNA ligase
FRZ59_03820	ENOG4108UUM	single-stranded DNA-binding protein
FRZ59_03840	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_03850	ENOG4105DZQ	phospholipase D Transphosphatidylase
FRZ59_03855	ENOG4105K5M	30s ribosomal protein S16
FRZ59_03860	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
FRZ59_03870	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
FRZ59_03875	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
FRZ59_03880	ENOG4105D64	Mechanosensitive ion channel
FRZ59_03885	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
FRZ59_03890	ENOG4105KNE	Phosphatidate cytidylyltransferase
FRZ59_03900	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
FRZ59_03915	ENOG4105CGY	Dna recombination protein
FRZ59_03920	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
FRZ59_03925	ENOG41061MV	Arylsulfatase
FRZ59_03930	ENOG4105CK2	sodium dicarboxylate symporter
FRZ59_03935	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FRZ59_03945	ENOG410624X	efflux transporter, rnd family, mfp subunit
FRZ59_03955	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
FRZ59_03965	ENOG4108Z0R	Transferase
FRZ59_03975	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
FRZ59_03980	ENOG4105K4T	epimerase
FRZ59_03985	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
FRZ59_04015	ENOG4105NAE	bifunctional deaminase-reductase domain protein
FRZ59_04020	ENOG41082BM	Transcriptional regulator, arsr family
FRZ59_04035	ENOG4105CZ9	Domain of unknown function (DU1801)
FRZ59_04050	ENOG4105BZU	Histidine kinase
FRZ59_04060	ENOG4108Q35	Adenylate
FRZ59_04065	ENOG4107UWA	esterase
FRZ59_04075	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
FRZ59_04080	ENOG410804X	Transcriptional regulator
FRZ59_04085	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_04110	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_04150	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_04185	ENOG4105CXK	mandelate racemase muconate lactonizing
FRZ59_04190	ENOG4105CHR	reductase
FRZ59_04195	ENOG4105D9R	oxidoreductase
FRZ59_04210	ENOG4105ETE	Transcriptional regulator (LacI family
FRZ59_04220	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
FRZ59_04255	ENOG4105FQP	Beta-lactamase
FRZ59_04265	ENOG4105E2D	ec 3.2.1.52
FRZ59_04285	ENOG4105C9K	Endothelin-converting enzyme 1
FRZ59_04300	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
FRZ59_04380	ENOG4105E6M	Sulphatase-modifying factor protein
FRZ59_04395	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_04425	ENOG4105CJ1	ABC, transporter
FRZ59_04430	ENOG4105CJ1	ABC, transporter
FRZ59_04435	ENOG4105D0S	secretion protein (HlyD
FRZ59_04450	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
FRZ59_04470	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
FRZ59_04515	ENOG4105C0D	helicase
FRZ59_04520	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
FRZ59_04525	ENOG4105C0H	protease
FRZ59_04530	ENOG4108NEV	two component transcriptional regulator, LytTR family
FRZ59_04535	ENOG4108HRK	Histidine kinase
FRZ59_04550	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
FRZ59_04585	ENOG41067XB	TonB family
FRZ59_04595	ENOG4105EJG	cellulose synthase
FRZ59_04600	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FRZ59_04605	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FRZ59_04610	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FRZ59_04615	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FRZ59_04635	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
FRZ59_04640	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FRZ59_04650	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FRZ59_04655	ENOG4105D65	subunit l
FRZ59_04665	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FRZ59_04675	ENOG4105F0N	pyrophosphate phospho-hydrolase
FRZ59_04680	ENOG4105C37	(CBS) domain
FRZ59_04695	ENOG4107QSA	Oxaloacetate decarboxylase
FRZ59_04720	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
FRZ59_04785	ENOG4106H3A	restriction
FRZ59_04820	ENOG4105Y49	secretion protein, HlyD family
FRZ59_04830	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FRZ59_04880	ENOG4105DT9	hydrolase family 43
FRZ59_04895	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
FRZ59_04920	ENOG4105DTQ	mandelate racemase muconate lactonizing
FRZ59_04935	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
FRZ59_04940	ENOG4105CH7	arginosuccinase
FRZ59_04945	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FRZ59_04950	ENOG4107T6X	nag kinase
FRZ59_04955	ENOG4107REN	Carbamoyltransferase
FRZ59_04960	ENOG4105C8Y	Acetylornithine aminotransferase
FRZ59_04970	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
FRZ59_04975	ENOG4105CDH	Citrulline--aspartate ligase
FRZ59_04995	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FRZ59_05010	ENOG4107VZS	Nicotinamide-nucleotide adenylyltransferase
FRZ59_05015	ENOG41088CQ	domain protein
FRZ59_05020	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
FRZ59_05035	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
FRZ59_05045	ENOG4105C03	ribonuclease
FRZ59_05055	ENOG4105K70	DNA-binding protein
FRZ59_05065	ENOG4108UUM	single-stranded DNA-binding protein
FRZ59_05070	ENOG4105C9M	aspartyl-trna synthetase
FRZ59_05075	ENOG4105GFR	rna polymerase sigma factor
FRZ59_05090	ENOG4105EE5	Membrane protein terC
FRZ59_05105	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
FRZ59_05125	ENOG4105CUT	histidyl-tRNA synthetase
FRZ59_05130	ENOG4105KJF	protein tyrosine phosphatase
FRZ59_05135	ENOG4105C9Q	fumarate hydratase class II
FRZ59_05145	ENOG4105C2M	dna polymerase I
FRZ59_05150	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FRZ59_05155	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FRZ59_05165	ENOG4105C30	Nad-dependent epimerase dehydratase
FRZ59_05185	ENOG4105BZU	Histidine kinase
FRZ59_05195	ENOG4105BZU	Histidine kinase
FRZ59_05205	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FRZ59_05210	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
FRZ59_05215	ENOG4105E39	Enoyl-CoA hydratase
FRZ59_05220	ENOG4105D5P	Methylmalonyl-coA mutase
FRZ59_05225	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
FRZ59_05230	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
FRZ59_05270	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FRZ59_05280	ENOG4105CX6	glutaminyL-tRNA synthetase
FRZ59_05285	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FRZ59_05290	ENOG4105BZU	Histidine kinase
FRZ59_05300	ENOG4107ZSV	Receptor
FRZ59_05310	ENOG4105EMN	RNA polymerase sigma factor
FRZ59_05330	ENOG4105UYK	outer membrane protein a
FRZ59_05335	ENOG4105CDV	Ompa motb domain protein
FRZ59_05355	ENOG4105D1Z	hydroxypyruvate reductase
FRZ59_05360	ENOG4105C6Z	Gluconate
FRZ59_05385	ENOG4108NS2	receptor
FRZ59_05390	ENOG4108HRK	Histidine kinase
FRZ59_05425	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
FRZ59_05440	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
FRZ59_05445	ENOG4105E0X	reductase
FRZ59_05475	ENOG4105C2C	drug resistance transporter, Bcr CflA
FRZ59_05485	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FRZ59_05495	ENOG4105CBG	Sulfatase
FRZ59_05500	ENOG4106KS4	Sulfatase
FRZ59_05520	ENOG4106UX7	integral membrane protein
FRZ59_05560	ENOG4105EUB	pirin domain protein
FRZ59_05575	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
FRZ59_05625	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_05660	ENOG4108MCI	Transcriptional regulator, ARAC family
FRZ59_05675	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
FRZ59_05680	ENOG4107RBB	ABC transporter, permease
FRZ59_05700	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_05715	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
FRZ59_05720	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
FRZ59_05850	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_05965	ENOG4105ECQ	AraC Family Transcriptional Regulator
FRZ59_05985	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
FRZ59_06025	ENOG4105DIA	mandelate racemase muconate lactonizing
FRZ59_06030	ENOG4105CPC	Aldo Keto reductase
FRZ59_06055	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_06080	ENOG4105ED2	Beta-lactamase
FRZ59_06090	ENOG4105VXP	Protein of unknown function DUF86
FRZ59_06110	ENOG4105EN2	IstB domain-containing protein ATP-binding protein
FRZ59_06150	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FRZ59_06165	ENOG4105CB5	ATP-dependent DNA helicase recG
FRZ59_06215	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FRZ59_06310	ENOG4105EKQ	RNA-directed DNA polymerase
FRZ59_06335	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
FRZ59_06345	ENOG4105K64	Glycosyl transferase, family 2
FRZ59_06360	ENOG4105CG5	Glycosyl transferase (Group 1
FRZ59_06375	ENOG4107S6X	Glycosyl transferase, family 2
FRZ59_06385	ENOG4105BZ1	(ABC) transporter
FRZ59_06415	ENOG4105CDV	Ompa motb domain protein
FRZ59_06425	ENOG4105FR1	rard protein
FRZ59_06440	ENOG4105BZ1	(ABC) transporter
FRZ59_06445	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
FRZ59_06450	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
FRZ59_06455	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
FRZ59_06460	ENOG4105CE9	30S ribosomal protein S2
FRZ59_06465	ENOG4108UJD	30S ribosomal protein S9
FRZ59_06470	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
FRZ59_06480	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
FRZ59_06490	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
FRZ59_06500	ENOG4105DK0	Indole-3-glycerol phosphate synthase
FRZ59_06505	ENOG4105DDQ	anthranilate synthase
FRZ59_06520	ENOG4105CI2	imidazolone-5-propionate hydrolase
FRZ59_06525	ENOG4108VVK	transcriptional Regulator, AsnC
FRZ59_06535	ENOG4105CPP	Dehydrogenase, E1 component
FRZ59_06540	ENOG4105C4R	Atp-dependent dna helicase
FRZ59_06565	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_06570	ENOG4105D17	glycoside hydrolase, family 3 domain protein
FRZ59_06595	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FRZ59_06600	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FRZ59_06605	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
FRZ59_06615	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
FRZ59_06620	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
FRZ59_06630	ENOG41068JE	domain protein
FRZ59_06645	ENOG4105C1V	Peptidase, M16
FRZ59_06655	ENOG4105ETE	Transcriptional regulator (LacI family
FRZ59_06660	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_06675	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_06685	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
FRZ59_06695	ENOG4105CTQ	phosphohexokinase
FRZ59_06700	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
FRZ59_06705	ENOG4105C0P	Mg chelatase subunit ChlI
FRZ59_06730	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_06755	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
FRZ59_06765	ENOG41083MR	nifu domain-containing protein
FRZ59_06770	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
FRZ59_06780	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
FRZ59_06785	ENOG4105FA2	dna polymerase iii
FRZ59_06790	ENOG4105MA4	psp1 domain protein
FRZ59_06800	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
FRZ59_06815	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
FRZ59_06820	ENOG4108RWN	rrna methyltransferase
FRZ59_06830	ENOG4105CI3	gtp-binding protein typa
FRZ59_06880	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
FRZ59_06885	ENOG4105ECJ	Glycosyl Transferase
FRZ59_06900	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FRZ59_06940	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
FRZ59_06955	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
FRZ59_06965	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
FRZ59_06980	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
FRZ59_07005	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
FRZ59_07015	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
FRZ59_07020	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
FRZ59_07040	ENOG4108SHN	Glycosyl transferase, family 2
FRZ59_07045	ENOG4105K64	Glycosyl transferase, family 2
FRZ59_07075	ENOG4105CG5	Glycosyl transferase (Group 1
FRZ59_07080	ENOG4107EF8	Glycosyl transferase (Group 1
FRZ59_07110	ENOG4108RB3	Capsular polysaccharide biosynthesis protein
FRZ59_07135	ENOG4107QQG	Dehydrogenase
FRZ59_07145	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
FRZ59_07155	ENOG4105D2T	synthase
FRZ59_07160	ENOG4107SE4	UDP-N-acetylglucosamine 2-epimerase
FRZ59_07200	ENOG4105EQK	-acetyltransferase
FRZ59_07205	ENOG4108UHC	Glycosyl transferase, wecb taga cpsf family
FRZ59_07220	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FRZ59_07230	ENOG4106QJ6	Integrase catalytic subunit
FRZ59_07235	ENOG4105EN2	IstB domain-containing protein ATP-binding protein
FRZ59_07240	ENOG4105CBG	Sulfatase
FRZ59_07250	ENOG4105F5W	AtP-binding protein
FRZ59_07305	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
FRZ59_07315	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
FRZ59_07330	ENOG4108I67	Catalyzes the synthesis of activated sulfate (By similarity)
FRZ59_07335	ENOG4105C11	sulfate adenylyltransferase), subunit 2
FRZ59_07345	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
FRZ59_07360	ENOG4105IIU	Aminopeptidase
FRZ59_07365	ENOG4108YZG	isomerase
FRZ59_07370	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
FRZ59_07375	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FRZ59_07385	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FRZ59_07390	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
FRZ59_07395	ENOG4105WXV	50S ribosomal protein L32
FRZ59_07405	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
FRZ59_07410	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FRZ59_07415	ENOG4108JQ1	Dehydrogenase
FRZ59_07430	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FRZ59_07470	ENOG4105CBG	Sulfatase
FRZ59_07475	ENOG41061MV	Arylsulfatase
FRZ59_07480	ENOG4105ETE	Transcriptional regulator (LacI family
FRZ59_07485	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_07490	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_07555	ENOG4105EPC	oxidoreductase
FRZ59_07570	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
FRZ59_07580	ENOG4105CTX	dehydratase
FRZ59_07600	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
FRZ59_07610	ENOG4107R8N	Glycosyl transferase, family 2
FRZ59_07615	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FRZ59_07620	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
FRZ59_07625	ENOG4108N5B	2-phosphosulfolactate phosphatase
FRZ59_07630	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
FRZ59_07640	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
FRZ59_07650	ENOG4105SYT	Methylenetetrahydrofolate reductase
FRZ59_07655	ENOG4105C3R	Methionine synthase
FRZ59_07675	ENOG4105C8U	phosphate abc transporter
FRZ59_07680	ENOG4105E2Z	phosphate ABC transporter (Permease
FRZ59_07685	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FRZ59_07690	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
FRZ59_07700	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FRZ59_07705	ENOG4105CN1	protease
FRZ59_07715	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
FRZ59_07720	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
FRZ59_07755	ENOG4105E0C	molybdate abc transporter
FRZ59_07760	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
FRZ59_07770	ENOG4105ECR	NmrA family
FRZ59_07775	ENOG4105KVH	Transcriptional regulator
FRZ59_07785	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
FRZ59_07800	ENOG4108RTU	Aldolase
FRZ59_07810	ENOG4105D2H	Uronic isomerase
FRZ59_07815	ENOG4107QZW	Altronate oxidoreductase
FRZ59_07820	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
FRZ59_07840	ENOG4105BZS	acriflavin resistance protein
FRZ59_07845	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
FRZ59_07850	ENOG4105C0H	protease
FRZ59_07860	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
FRZ59_07870	ENOG4105CHU	acetyl-coa acetyltransferase
FRZ59_07875	ENOG4105C1G	acyl-Coa dehydrogenase
FRZ59_07885	ENOG4105CFH	Aspartokinase
FRZ59_07890	ENOG4107RDY	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
FRZ59_07900	ENOG4108V1T	peptidylprolyl cis-trans isomerase
FRZ59_07930	ENOG4105C7S	Dehydrogenase
FRZ59_07965	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FRZ59_07970	ENOG4105C8S	subunit m
FRZ59_07975	ENOG4105D65	subunit l
FRZ59_07980	ENOG41080EA	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FRZ59_07985	ENOG4107UFS	subunit j
FRZ59_07990	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FRZ59_07995	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
FRZ59_08000	ENOG4108IEH	NADH dehydrogenase subunit g
FRZ59_08005	ENOG4107QIZ	NADH dehydrogenase
FRZ59_08015	ENOG4105GKE	subunit e
FRZ59_08025	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FRZ59_08030	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FRZ59_08055	ENOG4107R0I	Cell wall formation (By similarity)
FRZ59_08060	ENOG4105EMN	RNA polymerase sigma factor
FRZ59_08080	ENOG4105C8N	cysteinyl-tRNA synthetase
FRZ59_08100	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
FRZ59_08105	ENOG4107S1E	Beta-lactamase
FRZ59_08110	ENOG4105CPK	Glycosyl transferase (Group 1
FRZ59_08115	ENOG4105FE9	pseudouridine synthase
FRZ59_08140	ENOG4105E2D	ec 3.2.1.52
FRZ59_08145	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FRZ59_08150	ENOG4105MJ2	Competence protein
FRZ59_08160	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
FRZ59_08165	ENOG4105W5Q	DNA repair protein (RadC
FRZ59_08190	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
FRZ59_08215	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
FRZ59_08220	ENOG4105C1G	acyl-Coa dehydrogenase
FRZ59_08230	ENOG41083X6	30S ribosomal protein S21
FRZ59_08235	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FRZ59_08285	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
FRZ59_08290	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
FRZ59_08295	ENOG4107VNI	ribosomal protein l10
FRZ59_08300	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
FRZ59_08305	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FRZ59_08310	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FRZ59_08320	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
FRZ59_08335	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FRZ59_08340	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FRZ59_08350	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
FRZ59_08355	ENOG4105VEJ	Heat shock protein
FRZ59_08365	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FRZ59_08380	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
FRZ59_08395	ENOG4105C0B	DNA polymerase III (alpha subunit)
FRZ59_08410	ENOG4105EKQ	RNA-directed DNA polymerase
FRZ59_08430	ENOG4105C8Y	Acetylornithine aminotransferase
FRZ59_08435	ENOG4105C5I	Dehydrogenase
FRZ59_08440	ENOG4105JXH	GntR family transcriptional regulator
FRZ59_08450	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_08455	ENOG4105TT1	Ragb susd domain-containing protein
FRZ59_08460	ENOG4107RJ1	sodium solute
FRZ59_08465	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
FRZ59_08480	ENOG41061MV	Arylsulfatase
FRZ59_08485	ENOG4105CBG	Sulfatase
FRZ59_08505	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_08535	ENOG4107RJ1	sodium solute
FRZ59_08545	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_08590	ENOG4107RJ1	sodium solute
FRZ59_08595	ENOG4105JXH	GntR family transcriptional regulator
FRZ59_08600	ENOG4106KS4	Sulfatase
FRZ59_08620	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_08650	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_08665	ENOG4105CBG	Sulfatase
FRZ59_08670	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FRZ59_08685	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FRZ59_08690	ENOG4107RJ1	sodium solute
FRZ59_08695	ENOG4105D7N	magnesium and cobalt transport protein CorA
FRZ59_08750	ENOG4105CE1	Ferrous iron transport protein b
FRZ59_08780	ENOG4106HBX	Transcriptional Regulator AraC Family
FRZ59_08800	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_08815	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_08865	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
FRZ59_08895	ENOG4105CEV	competence damage-inducible protein
FRZ59_08905	ENOG4108Z9Z	response to DNA damage stimulus
FRZ59_08915	ENOG4107RBB	ABC transporter, permease
FRZ59_08990	ENOG4105CKK	Glycosyl transferase, family 2
FRZ59_09000	ENOG4105BZS	acriflavin resistance protein
FRZ59_09010	ENOG4105BZS	acriflavin resistance protein
FRZ59_09020	ENOG4106QJ6	Integrase catalytic subunit
FRZ59_09025	ENOG4105EN2	IstB domain-containing protein ATP-binding protein
FRZ59_09050	ENOG4107RBB	ABC transporter, permease
FRZ59_09065	ENOG4105EPC	oxidoreductase
FRZ59_09075	ENOG4105CHR	reductase
FRZ59_09115	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
FRZ59_09130	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FRZ59_09135	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
FRZ59_09140	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
FRZ59_09145	ENOG4105C72	UPF0176 protein
FRZ59_09160	ENOG4105EXW	epimerase dehydratase
FRZ59_09170	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
FRZ59_09175	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
FRZ59_09200	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_09220	ENOG4105DU6	RNA polymerase
FRZ59_09290	ENOG4105CHM	Aminotransferase
FRZ59_09300	ENOG4105CPP	Dehydrogenase, E1 component
FRZ59_09305	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
FRZ59_09310	ENOG4107S18	3-phosphoshikimate 1-carboxyvinyltransferase
FRZ59_09315	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
FRZ59_09320	ENOG4105CQC	Prephenate dehydratase
FRZ59_09325	ENOG4105D49	3-dehydroquinate synthase
FRZ59_09335	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
FRZ59_09340	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FRZ59_09350	ENOG41083ND	50S ribosomal protein L33
FRZ59_09355	ENOG4105KDC	50s ribosomal protein l28
FRZ59_09365	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FRZ59_09370	ENOG4108DMA	Nad-dependent epimerase dehydratase
FRZ59_09375	ENOG4105EMU	Dehydrogenase
FRZ59_09385	ENOG4105CMQ	Chloride channel
FRZ59_09390	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
FRZ59_09400	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FRZ59_09440	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_09455	ENOG4105VN1	Heat shock protein
FRZ59_09485	ENOG4105CBG	Sulfatase
FRZ59_09520	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_09530	ENOG4105DQ6	Transposase
FRZ59_09545	ENOG4105W3H	MtN3 and saliva related transmembrane protein
FRZ59_09595	ENOG4105ENH	Sulfatase
FRZ59_09610	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FRZ59_09615	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
FRZ59_09675	ENOG4105EQN	UPF0261 protein
FRZ59_09685	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
FRZ59_09690	ENOG4105C8P	)-transporter
FRZ59_09700	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FRZ59_09710	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_09720	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_09750	ENOG4105DFS	Conserved Protein
FRZ59_09760	ENOG4105DTN	riboflavin biosynthesis protein ribF
FRZ59_09765	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
FRZ59_09770	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
FRZ59_09780	ENOG4107RJ9	Cell division protein FtsX
FRZ59_09785	ENOG4105C8T	Leucyl-tRNA synthetase
FRZ59_09795	ENOG4105EP8	Glycosyl Hydrolase Family 88
FRZ59_09800	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
FRZ59_09810	ENOG4105CHR	reductase
FRZ59_09835	ENOG4105VEQ	Cold shock protein
FRZ59_09840	ENOG4105CN9	Peptidase m42 family protein
FRZ59_09845	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FRZ59_09855	ENOG4107QX3	carboxylase
FRZ59_09860	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FRZ59_09870	ENOG4105CHH	sulfate transporter
FRZ59_09875	ENOG41077A9	carbonic anhydrase
FRZ59_09890	ENOG4108YZY	peptidylprolyl cis-trans isomerase
FRZ59_09900	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
FRZ59_09910	ENOG4105CWX	Alpha-1,2-mannosidase
FRZ59_09925	ENOG4105DVE	abc transporter atp-binding protein
FRZ59_09935	ENOG4108ZCU	PPIases accelerate the folding of proteins
FRZ59_09955	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
FRZ59_09960	ENOG4108I0Z	Aconitate hydratase
FRZ59_09975	ENOG4108ZJ4	polysaccharide deacetylase
FRZ59_09980	ENOG4105BZU	Histidine kinase
FRZ59_09995	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FRZ59_10045	ENOG4105C0D	helicase
FRZ59_10050	ENOG41067HZ	cytochrome C, class I
FRZ59_10060	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FRZ59_10070	ENOG410624X	efflux transporter, rnd family, mfp subunit
FRZ59_10080	ENOG4105C6T	cysteine synthase
FRZ59_10085	ENOG4105D7W	serine acetyltransferase
FRZ59_10095	ENOG4105CRK	lysyL-tRNA synthetase
FRZ59_10100	ENOG4105VEQ	Cold shock protein
FRZ59_10105	ENOG4105C1J	atp-dependent rna helicase
FRZ59_10110	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
FRZ59_10115	ENOG4105EW9	transcriptional regulator AsnC family
FRZ59_10130	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
FRZ59_10160	ENOG4105CUY	Mechanosensitive ion channel
FRZ59_10170	ENOG4108HKT	sucrose-6-phosphate hydrolase
FRZ59_10195	ENOG4105NAE	bifunctional deaminase-reductase domain protein
FRZ59_10200	ENOG4105NAE	bifunctional deaminase-reductase domain protein
FRZ59_10220	ENOG4105C6Z	Gluconate
FRZ59_10250	ENOG4108NEV	two component transcriptional regulator, LytTR family
FRZ59_10255	ENOG4108HRK	Histidine kinase
FRZ59_10260	ENOG4108HRK	Histidine kinase
FRZ59_10295	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_10300	ENOG4106HBX	Transcriptional Regulator AraC Family
FRZ59_10305	ENOG4105CPQ	Dehydrogenase
FRZ59_10315	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
FRZ59_10320	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
FRZ59_10340	ENOG4108IQE	Amp-dependent synthetase and ligase
FRZ59_10345	ENOG4108Z4V	iron-sulfur cluster assembly
FRZ59_10350	ENOG4105C3J	Cysteine desulfurase
FRZ59_10355	ENOG4108ZVT	methylmalonyl-coA epimerase
FRZ59_10365	ENOG4105NRA	50s ribosomal protein l31 type b
FRZ59_10375	ENOG4105CP7	Triose-phosphate isomerase
FRZ59_10380	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FRZ59_10385	ENOG4105CNU	cell division protein FtsK
FRZ59_10400	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
FRZ59_10425	ENOG4108V06	Glutathione peroxidase
FRZ59_10455	ENOG4108Z03	MAF-like protein
FRZ59_10470	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FRZ59_10480	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
FRZ59_10485	ENOG4105CDY	transcriptional regulatory protein
FRZ59_10490	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
FRZ59_10495	ENOG4105CUB	amino acid
FRZ59_10525	ENOG4109015	Biopolymer transport protein exbD tolR
FRZ59_10555	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
FRZ59_10565	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FRZ59_10585	ENOG4105CAT	Cytidine monophosphate kinase
FRZ59_10600	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FRZ59_10605	ENOG4108R6K	riboflavin synthase, subunit alpha
FRZ59_10610	ENOG4105FQP	Beta-lactamase
FRZ59_10625	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FRZ59_10635	ENOG4105EPC	oxidoreductase
FRZ59_10650	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
FRZ59_10660	ENOG4105C31	Tryptophanyl-tRNA synthetase
FRZ59_10670	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FRZ59_10675	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FRZ59_10695	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
FRZ59_10700	ENOG4107RBB	ABC transporter, permease
FRZ59_10715	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_10735	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_10775	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
FRZ59_10780	ENOG4105CHM	Aminotransferase
FRZ59_10790	ENOG4105CHR	reductase
FRZ59_10795	ENOG4105DEN	Luciferase family
FRZ59_10820	ENOG4107QI1	Mate efflux family protein
FRZ59_10845	ENOG4105WKZ	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
FRZ59_10850	ENOG4105D70	Integrase catalytic subunit
FRZ59_10855	ENOG4105F5W	AtP-binding protein
FRZ59_10875	ENOG4106A4F	Removes the N-terminal methionine from nascent proteins (By similarity)
FRZ59_10880	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FRZ59_10885	ENOG4105EN2	IstB domain-containing protein ATP-binding protein
FRZ59_10905	ENOG4108UDW	Transcriptional regulator, luxr family
FRZ59_10915	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FRZ59_10995	ENOG4105WH1	Two component transcriptional regulator luxr family
FRZ59_11015	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FRZ59_11035	ENOG4105IRW	patatin-like phospholipase family protein
FRZ59_11045	ENOG4107RBB	ABC transporter, permease
FRZ59_11070	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FRZ59_11075	ENOG4105BZA	Phosphoglycerate kinase
FRZ59_11080	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
FRZ59_11095	ENOG41080FQ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FRZ59_11100	ENOG4105D65	subunit l
FRZ59_11105	ENOG4105C8S	subunit m
FRZ59_11110	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FRZ59_11115	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
FRZ59_11125	ENOG4108S4H	thioesterase Superfamily protein
FRZ59_11130	ENOG4105D78	K07001 NTE family protein
FRZ59_11140	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
FRZ59_11145	ENOG4108RWN	rrna methyltransferase
FRZ59_11160	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
FRZ59_11165	ENOG4105C5H	ABC transporter
FRZ59_11210	ENOG4108Q5Y	Membrane
FRZ59_11220	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FRZ59_11230	ENOG4105DZG	Dehydrogenase
FRZ59_11235	ENOG41061MV	Arylsulfatase
FRZ59_11240	ENOG4105C59	p-type ATPase
FRZ59_11250	ENOG4105EI3	2-dehydro-3-deoxygalactonokinase EC 2.7.1.58
FRZ59_11270	ENOG41065KQ	synthase
FRZ59_11305	ENOG4105XA0	heptosyltransferase ii
FRZ59_11310	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
FRZ59_11320	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
FRZ59_11325	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
FRZ59_11365	ENOG4107QRT	dEAD DEAH box helicase
FRZ59_11370	ENOG4107Y80	Major Facilitator superfamily
FRZ59_11380	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
FRZ59_11400	ENOG4107V87	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity)
FRZ59_11405	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FRZ59_11410	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
FRZ59_11420	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FRZ59_11455	ENOG4108RG0	uracil-dna glycosylase
FRZ59_11470	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_11495	ENOG4108X7A	Terpene synthase metal-binding domain-containing protein
FRZ59_11500	ENOG4105WPR	Transcriptional regulator, ARAC family
FRZ59_11530	ENOG4105VDW	Csbd family
FRZ59_11535	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
FRZ59_11550	ENOG4105DQE	DNA ligase
FRZ59_11555	ENOG4105FDF	Could be involved in DNA repair (By similarity)
FRZ59_11565	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FRZ59_11570	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FRZ59_11575	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FRZ59_11580	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FRZ59_11585	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FRZ59_11595	ENOG4105D05	Receptor
FRZ59_11610	ENOG4107QQR	Sporulation
FRZ59_11635	ENOG4105I7S	Abortive infection protein
FRZ59_11640	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
FRZ59_11645	ENOG4105D64	Mechanosensitive ion channel
FRZ59_11655	ENOG4108D7R	p-hydroxycinnamoyl CoA hydratase lyase
FRZ59_11660	ENOG4107ZP9	ComEC Rec2-related protein
FRZ59_11710	ENOG4105DR5	peptidase
FRZ59_11715	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
FRZ59_11725	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
FRZ59_11730	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FRZ59_11735	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FRZ59_11740	ENOG4105BZU	Histidine kinase
FRZ59_11750	ENOG4105EI2	Pseudouridine synthase
FRZ59_11770	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
FRZ59_11775	ENOG41066UZ	arginase EC 3.5.3.1
FRZ59_11780	ENOG4105C75	arginyL-tRNA synthetase
FRZ59_11790	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
FRZ59_11800	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_11810	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
FRZ59_11815	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FRZ59_11820	ENOG4105CWX	Alpha-1,2-mannosidase
FRZ59_11825	ENOG4106N3A	copper homeostasis protein cutc
FRZ59_11835	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
FRZ59_11840	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
FRZ59_11850	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FRZ59_11855	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FRZ59_11860	ENOG4105CAK	Cell division ATP-binding protein ftsE
FRZ59_11885	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
FRZ59_11895	ENOG4107YZX	Universal stress protein
FRZ59_11900	ENOG4105CB2	alcohol dehydrogenase
FRZ59_11910	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
FRZ59_11915	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
FRZ59_11920	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
FRZ59_11925	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
FRZ59_11930	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
FRZ59_11935	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FRZ59_11940	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
FRZ59_11945	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
FRZ59_11950	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FRZ59_11955	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
FRZ59_11970	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FRZ59_11990	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
FRZ59_11995	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
FRZ59_12000	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
FRZ59_12005	ENOG4105DUX	Transporter
FRZ59_12010	ENOG4105C5Z	peptidase
FRZ59_12020	ENOG4105CHU	acetyl-coa acetyltransferase
FRZ59_12025	ENOG4105CTJ	Metal Dependent Phosphohydrolase
FRZ59_12040	ENOG4107RBB	ABC transporter, permease
FRZ59_12095	ENOG4105EU0	Major facilitator Superfamily
FRZ59_12100	ENOG4107YCY	Transcriptional regulator
FRZ59_12120	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
FRZ59_12145	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
FRZ59_12155	ENOG4107ZXU	DSBA oxidoreductase
FRZ59_12165	ENOG4105E0K	tonB-dependent siderophore receptor
FRZ59_12205	ENOG4107VMU	Membrane
FRZ59_12210	ENOG4108Z9Z	response to DNA damage stimulus
FRZ59_12225	ENOG4105KVH	Transcriptional regulator
FRZ59_12300	ENOG4105EN2	IstB domain-containing protein ATP-binding protein
FRZ59_12305	ENOG4106QJ6	Integrase catalytic subunit
FRZ59_12345	ENOG4108YYS	metal-dependent hydrolase (By similarity)
FRZ59_12365	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_12390	ENOG4105E2D	ec 3.2.1.52
FRZ59_12400	ENOG4105E2D	ec 3.2.1.52
FRZ59_12415	ENOG4107QR9	Iron-sulfur cluster binding protein
FRZ59_12420	ENOG4108ZZK	Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source (By similarity)
FRZ59_12425	ENOG4105CHR	reductase
FRZ59_12445	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FRZ59_12450	ENOG4105C0B	DNA polymerase III (alpha subunit)
FRZ59_12455	ENOG4105HSS	phospholipase C
FRZ59_12495	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
FRZ59_12500	ENOG41061MV	Arylsulfatase
FRZ59_12530	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_12535	ENOG4105C3M	thioredoxin reductase
FRZ59_12545	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
FRZ59_12565	ENOG4107S9Q	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
FRZ59_12570	ENOG4105CG3	alpha amylase, catalytic region
FRZ59_12575	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
FRZ59_12635	ENOG41080U6	GntR family transcriptional regulator
FRZ59_12650	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_12660	ENOG4105CWX	Alpha-1,2-mannosidase
FRZ59_12665	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FRZ59_12670	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FRZ59_12680	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
FRZ59_12685	ENOG4106H78	methyltransferase
FRZ59_12695	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FRZ59_12710	ENOG4105VCH	membrane
FRZ59_12720	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FRZ59_12725	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
FRZ59_12730	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
FRZ59_12735	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
FRZ59_12765	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
FRZ59_12775	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
FRZ59_12785	ENOG4105DKQ	ROK family
FRZ59_12790	ENOG4108UQ1	hydrolase, family 25
FRZ59_12815	ENOG4105DXN	mazG family
FRZ59_12835	ENOG4105D60	lipoprotein releasing system transmembrane protein
FRZ59_12840	ENOG4105DKW	ABC transporter
FRZ59_12845	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FRZ59_12870	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
FRZ59_12875	ENOG4105C3S	Mate efflux family protein
FRZ59_12900	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
FRZ59_12910	ENOG4105K46	50S ribosomal protein l27
FRZ59_12915	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
FRZ59_12920	ENOG4105C3M	thioredoxin reductase
FRZ59_12925	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
FRZ59_12930	ENOG4105D7N	magnesium and cobalt transport protein CorA
FRZ59_12935	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FRZ59_12955	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FRZ59_12985	ENOG4105C7B	Threonine dehydratase
FRZ59_12995	ENOG4105C7K	acetolactate synthase
FRZ59_13000	ENOG4108ZP8	Acetolactate synthase small subunit
FRZ59_13005	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
FRZ59_13010	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FRZ59_13025	ENOG4105VIG	Sec-independent protein translocase protein TatC
FRZ59_13040	ENOG41067HZ	cytochrome C, class I
FRZ59_13050	ENOG410847I	Transcriptional regulator, BadM Rrf2 family
FRZ59_13070	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FRZ59_13075	ENOG4105K6T	rare lipoprotein A
FRZ59_13085	ENOG4105BZ1	(ABC) transporter
FRZ59_13095	ENOG4107R6T	Involved in the transcription termination process (By similarity)
FRZ59_13105	ENOG4105VIE	preprotein translocase, subunit YajC
FRZ59_13115	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
FRZ59_13130	ENOG4107QKV	phosphomannomutase
FRZ59_13135	ENOG4107QI6	Cysteine desulfurase
FRZ59_13140	ENOG4105D2N	Aldolase
FRZ59_13145	ENOG4108IDZ	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
FRZ59_13150	ENOG4105EIE	fructose-bisphosphate aldolase
FRZ59_13165	ENOG4105D05	Receptor
FRZ59_13175	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
FRZ59_13180	ENOG4108KEZ	Dehydrogenase
FRZ59_13185	ENOG4105C01	Dihydroxy-acid dehydratase
FRZ59_13195	ENOG4108ZGC	gaf domain protein
FRZ59_13205	ENOG4108VX5	3-methyladenine DNA glycosylase
FRZ59_13210	ENOG4107W2A	UPF0173 metal-dependent hydrolase
FRZ59_13220	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FRZ59_13235	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FRZ59_13245	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_13255	ENOG4105DVY	radical SAM domain protein
FRZ59_13265	ENOG4105EV6	Pfam:DUF178
FRZ59_13270	ENOG4107RI6	Anthranilate phosphoribosyltransferase
FRZ59_13275	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
FRZ59_13280	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FRZ59_13285	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
FRZ59_13290	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
FRZ59_13295	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
FRZ59_13300	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
FRZ59_13315	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FRZ59_13330	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
FRZ59_13335	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FRZ59_13350	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
FRZ59_13365	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
FRZ59_13405	ENOG4108NEV	two component transcriptional regulator, LytTR family
FRZ59_13410	ENOG4105C5H	ABC transporter
FRZ59_13415	ENOG4105JXH	GntR family transcriptional regulator
FRZ59_13430	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FRZ59_13445	ENOG4108VPT	UPF0234 protein
FRZ59_13450	ENOG4105EAA	nucleoside
FRZ59_13455	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
FRZ59_13470	ENOG4105CQB	FAD linked oxidase domain protein
FRZ59_13475	ENOG4105KRF	dihydroneopterin aldolase
FRZ59_13480	ENOG4105C1G	acyl-Coa dehydrogenase
FRZ59_13495	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
FRZ59_13500	ENOG4105CFH	Aspartokinase
FRZ59_13510	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
FRZ59_13525	ENOG4107TJ9	Cytochrome
FRZ59_13540	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
FRZ59_13545	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
FRZ59_13550	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
FRZ59_13555	ENOG4108ZG0	Ompa motb domain protein
FRZ59_13560	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
FRZ59_13565	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FRZ59_13570	ENOG4105C2X	Arabinose 5-phosphate isomerase
FRZ59_13575	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
FRZ59_13585	ENOG4105CH6	catalase
FRZ59_13590	ENOG4105DQ6	Transposase
FRZ59_13600	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FRZ59_13605	ENOG4105CDU	Replicative dna helicase
FRZ59_13620	ENOG4108V06	Glutathione peroxidase
FRZ59_13630	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
FRZ59_13640	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FRZ59_13655	ENOG4105CPN	adenine deaminase
FRZ59_13665	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
FRZ59_13670	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
FRZ59_13675	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FRZ59_13685	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
FRZ59_13705	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
FRZ59_13715	ENOG4107GJV	short-chain dehydrogenase reductase
FRZ59_13720	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_13735	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
FRZ59_13745	ENOG4108URH	decarboxylase
FRZ59_13760	ENOG4105EPC	oxidoreductase
FRZ59_13765	ENOG4108JQB	penicillin-binding protein 1C
FRZ59_13790	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FRZ59_13795	ENOG4105BZU	Histidine kinase
FRZ59_13800	ENOG4105C79	DNA protecting protein DprA
FRZ59_13805	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
FRZ59_13815	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
FRZ59_13845	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FRZ59_13855	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FRZ59_13865	ENOG4105C3K	feS assembly ATPase SufC
FRZ59_13875	ENOG4105C9B	Cysteine desulfurase
FRZ59_13885	ENOG4105VG1	fes assembly suf system protein
FRZ59_13890	ENOG4107PU6	Membrane
FRZ59_13900	ENOG4105C7Z	Conserved Protein
FRZ59_13905	ENOG4105DTD	Dehydrogenase
FRZ59_13910	ENOG4105C28	cystathionine
FRZ59_13915	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
FRZ59_13920	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
FRZ59_13925	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
FRZ59_13955	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
FRZ59_13960	ENOG4108HRK	Histidine kinase
FRZ59_13965	ENOG4108VAC	response regulator
FRZ59_13970	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
FRZ59_13980	ENOG4107QWK	SAICAR synthetase
FRZ59_13985	ENOG4105C9A	Phoh family
FRZ59_13990	ENOG4107V4F	S-adenosyl-l-methionine hydroxide adenosyltransferase
FRZ59_13995	ENOG4108JQC	penicillin-binding protein 1A
FRZ59_14010	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FRZ59_14035	ENOG4105C10	Electron transfer flavoprotein
FRZ59_14050	ENOG4105EM2	membrane
FRZ59_14075	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
FRZ59_14125	ENOG4107SBE	Glycosyl transferase (Group 1
FRZ59_14145	ENOG4105D75	Capsular exopolysaccharide family
FRZ59_14170	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
FRZ59_14195	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
FRZ59_14205	ENOG4105CY3	ABC transporter, permease
FRZ59_14210	ENOG4105DHJ	ABC, transporter
FRZ59_14220	ENOG4105CIY	formyltetrahydrofolate deformylase
FRZ59_14250	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
FRZ59_14270	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FRZ59_14275	ENOG4105CI2	imidazolone-5-propionate hydrolase
FRZ59_14280	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
FRZ59_14285	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
FRZ59_14290	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
FRZ59_14300	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FRZ59_14305	ENOG4107R7I	amino acid
FRZ59_14315	ENOG4105D82	Glutamate dehydrogenase
FRZ59_14330	ENOG4105DZP	Membrane-associated zinc metalloprotease
FRZ59_14335	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
FRZ59_14350	ENOG4105CKK	Glycosyl transferase, family 2
FRZ59_14365	ENOG4105CD3	dihydroorotase
FRZ59_14380	ENOG4107QN2	dihydrolipoyl dehydrogenase
FRZ59_14405	ENOG4105C3G	gtp-binding protein
FRZ59_14410	ENOG4105VG0	50S ribosomal protein l34
FRZ59_14415	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
FRZ59_14425	ENOG4105CN1	protease
FRZ59_14430	ENOG4105HF0	Membrane
FRZ59_14435	ENOG41072GX	Peptidase M22 Glycoprotease
FRZ59_14445	ENOG4105M08	Membrane
FRZ59_14450	ENOG4105C25	Primosomal protein n'
FRZ59_14455	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
FRZ59_14465	ENOG4105C1J	atp-dependent rna helicase
FRZ59_14470	ENOG4105CD3	dihydroorotase
FRZ59_14495	ENOG4108JJ7	ABC transporter
FRZ59_14510	ENOG4105CHP	RNA polymerase
FRZ59_14565	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_14570	ENOG4105TT1	Ragb susd domain-containing protein
FRZ59_14575	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
FRZ59_14595	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
FRZ59_14600	ENOG4108YYC	ycei family
FRZ59_14630	ENOG4105EMN	RNA polymerase sigma factor
FRZ59_14640	ENOG4105EN6	Membrane
FRZ59_14650	ENOG41067HS	methyltransferase
FRZ59_14680	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
FRZ59_14695	ENOG4105C28	cystathionine
FRZ59_14705	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
FRZ59_14720	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
FRZ59_14735	ENOG4105F7J	membrane-bound serine protease
FRZ59_14745	ENOG41068JE	domain protein
FRZ59_14750	ENOG4105DBI	uridine monophosphokinase
FRZ59_14765	ENOG4105DFA	alanine racemase domain protein
FRZ59_14785	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
FRZ59_14790	ENOG4105VJV	50s ribosomal protein L35
FRZ59_14795	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
FRZ59_14820	ENOG4105C6Z	Gluconate
FRZ59_14870	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
FRZ59_14875	ENOG4105DEU	major facilitator superfamily
FRZ59_14900	ENOG4105BZ1	(ABC) transporter
FRZ59_14920	ENOG4108JQ1	Dehydrogenase
FRZ59_14925	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
FRZ59_14930	ENOG4105DJV	ribulose-phosphate 3-epimerase
FRZ59_14940	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FRZ59_14945	ENOG4105D3R	alkyl hydroperoxide reductase
FRZ59_14955	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
FRZ59_14965	ENOG4105CPF	Cell wall formation (By similarity)
FRZ59_14985	ENOG4107U9T	Pfam:Ribonuclease_BN
FRZ59_14995	ENOG4107YHX	fad dependent oxidoreductase
FRZ59_15000	ENOG4105W5Z	
FRZ59_15015	ENOG4105EUB	pirin domain protein
FRZ59_15035	ENOG4105NPE	arsR family transcriptional regulator
FRZ59_15055	ENOG4105NAE	bifunctional deaminase-reductase domain protein
FRZ59_15085	ENOG4105DMF	Dehydrogenase
FRZ59_15105	ENOG4105DQE	DNA ligase
FRZ59_15120	ENOG4105F6U	Short-chain dehydrogenase reductase Sdr
FRZ59_15125	ENOG4105KVH	Transcriptional regulator
FRZ59_15150	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
FRZ59_15155	ENOG4105CNN	ABC, transporter
FRZ59_15160	ENOG4105C2J	ABC transporter
FRZ59_15170	ENOG4105WEF	catalase
FRZ59_15185	ENOG4105D8V	Glucose sorbosone dehydrogenase
FRZ59_15190	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
FRZ59_15205	ENOG4107MM9	BNR Asp-box repeat-containing protein
FRZ59_15225	ENOG4105FQP	Beta-lactamase
FRZ59_15230	ENOG4108KBJ	Inner membrane protein YkgB
FRZ59_15255	ENOG4105WH1	Two component transcriptional regulator luxr family
FRZ59_15275	ENOG41061MV	Arylsulfatase
FRZ59_15340	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
FRZ59_15370	ENOG41086D8	Transcriptional regulator
FRZ59_15375	ENOG4108A04	Beta-lactamase
FRZ59_15385	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
FRZ59_15390	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
FRZ59_15420	ENOG4106FGB	Beta-lactamase
FRZ59_15445	ENOG4105DQ6	Transposase
FRZ59_15470	ENOG4106QJ6	Integrase catalytic subunit
FRZ59_15480	ENOG4105EN2	IstB domain-containing protein ATP-binding protein
FRZ59_15535	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FRZ59_15565	ENOG4105W5Q	DNA repair protein (RadC
FRZ59_15600	ENOG4105DQ6	Transposase
FRZ59_15665	ENOG4106QJ6	Integrase catalytic subunit
FRZ59_15670	ENOG4105EN2	IstB domain-containing protein ATP-binding protein
FRZ59_15700	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
FRZ59_15705	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
FRZ59_15710	ENOG4108UJU	UPF0301 protein
FRZ59_15750	ENOG41083MR	nifu domain-containing protein
FRZ59_15755	ENOG4105ECY	inositol monophosphatase
FRZ59_15760	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FRZ59_15765	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
FRZ59_15785	ENOG4105C8U	phosphate abc transporter
FRZ59_15795	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FRZ59_15805	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FRZ59_15810	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
FRZ59_15815	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FRZ59_15825	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
FRZ59_15830	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
FRZ59_15840	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
FRZ59_15845	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
FRZ59_15865	ENOG4105CM2	brancheD-chain amino acid aminotransferase
FRZ59_15870	ENOG4105C34	Pseudouridine synthase
FRZ59_15890	ENOG4108Z0Z	intracellular protease Pfpi family
FRZ59_15895	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FRZ59_15900	ENOG4105C5S	asparaginyl-tRNA synthetase
FRZ59_15905	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
FRZ59_15915	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
FRZ59_15920	ENOG4107SN7	NLP P60 protein
FRZ59_15935	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
FRZ59_15940	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
FRZ59_15945	ENOG4105EMN	RNA polymerase sigma factor
FRZ59_15960	ENOG4105C7S	Dehydrogenase
FRZ59_15965	ENOG4105CEV	competence damage-inducible protein
FRZ59_15980	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
FRZ59_16000	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
FRZ59_16005	ENOG4105VFU	Rna-binding protein
FRZ59_16015	ENOG4105EPD	Oligopeptide transporter, Opt family
FRZ59_16020	ENOG4105CMG	Carbohydrate kinase
FRZ59_16025	ENOG4105CWX	Alpha-1,2-mannosidase
FRZ59_16050	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
FRZ59_16055	ENOG4105D6E	homoserine dehydrogenase
FRZ59_16065	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
FRZ59_16070	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
FRZ59_16085	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
FRZ59_16110	ENOG4105D7Z	glutathione synthase
FRZ59_16115	ENOG4105DT9	hydrolase family 43
FRZ59_16120	ENOG4105DCG	PHP domain protein
FRZ59_16125	ENOG4105CE4	GlcNAc 6-P deacetylase
FRZ59_16130	ENOG4105D16	lipopolysaccharide heptosyltransferase i
FRZ59_16145	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
FRZ59_16150	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
FRZ59_16165	ENOG4108J2P	Alpha beta hydrolase fold
FRZ59_16175	ENOG4108UW5	maltose o-acetyltransferase
FRZ59_16185	ENOG4105C1J	atp-dependent rna helicase
FRZ59_16195	ENOG4105T38	integral membrane protein
FRZ59_16205	ENOG4105C5H	ABC transporter
FRZ59_16210	ENOG4105C0D	helicase
FRZ59_16215	ENOG4108YYS	metal-dependent hydrolase (By similarity)
FRZ59_16250	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
FRZ59_16255	ENOG4105CGK	Exodeoxyribonuclease III
FRZ59_16295	ENOG4105CPC	Aldo Keto reductase
FRZ59_16300	ENOG4105WHD	thiamine biosynthesis protein ThiS
FRZ59_16305	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
FRZ59_16315	ENOG4105DWF	phosphomethylpyrimidine kinase
FRZ59_16320	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
FRZ59_16325	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
FRZ59_16330	ENOG4105D41	biosynthesis protein thiH
FRZ59_16335	ENOG4105D06	uba thif-type nad fad binding protein
FRZ59_16340	ENOG4105E98	transcriptional regulator DeoR family
FRZ59_16355	ENOG4105IE8	Alpha-ketoglutarate permease
FRZ59_16360	ENOG4108M3J	Dehydrogenase
FRZ59_16370	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
FRZ59_16380	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
FRZ59_16395	ENOG4105D63	family UPF0324
FRZ59_16405	ENOG4105KPY	Small multidrug resistance protein
FRZ59_16410	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FRZ59_16430	ENOG4105E09	nadh pyrophosphatase
FRZ59_16435	ENOG4105EKQ	RNA-directed DNA polymerase
FRZ59_16445	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_16455	ENOG4105PFC	Transcriptional regulator
FRZ59_16460	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
FRZ59_16465	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FRZ59_16470	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
FRZ59_16475	ENOG4105D2H	Uronic isomerase
FRZ59_16480	ENOG4105F5H	Glycosyl Hydrolase Family 88
FRZ59_16490	ENOG4105TT1	Ragb susd domain-containing protein
FRZ59_16500	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_16510	ENOG4105ETE	Transcriptional regulator (LacI family
FRZ59_16530	ENOG4105CJ1	ABC, transporter
FRZ59_16570	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_16590	ENOG41061H0	Monooxygenase
FRZ59_16680	ENOG4105VCH	membrane
FRZ59_16710	ENOG4105NPE	arsR family transcriptional regulator
FRZ59_16770	ENOG4105VZ8	Transcriptional regulator
FRZ59_16800	ENOG41082AG	Plasmid maintenance system antidote protein
FRZ59_16805	ENOG4105EKQ	RNA-directed DNA polymerase
FRZ59_16815	ENOG4105DI5	UPF0365 protein
FRZ59_16820	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
FRZ59_16830	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
FRZ59_16870	ENOG4105C1Q	protoporphyrinogen oxidase
FRZ59_16875	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
FRZ59_16880	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FRZ59_16885	ENOG4105BZU	Histidine kinase
FRZ59_16890	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
FRZ59_16895	ENOG4105D52	delta-aminolevulinic acid dehydratase
FRZ59_16900	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
FRZ59_16905	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
FRZ59_16910	ENOG4105D3R	alkyl hydroperoxide reductase
FRZ59_16920	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
FRZ59_16945	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FRZ59_16950	ENOG4105VZ9	UPF0235 protein
FRZ59_17075	ENOG4105BZU	Histidine kinase
FRZ59_17105	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
FRZ59_17120	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
FRZ59_17145	ENOG4105C28	cystathionine
FRZ59_17155	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
FRZ59_17180	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FRZ59_17185	ENOG4108YYC	ycei family
FRZ59_17190	ENOG4108YYH	Nadph-dependent fmn reductase
FRZ59_17200	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
FRZ59_17230	ENOG4105H67	Protein of unknown function (DUF421)
FRZ59_17260	ENOG4105CG3	alpha amylase, catalytic region
FRZ59_17265	ENOG41079Y2	Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone
FRZ59_17280	ENOG4108S01	response regulator
FRZ59_17285	ENOG4105CBG	Sulfatase
FRZ59_17345	ENOG4105CVN	desaturase
FRZ59_17370	ENOG4105DF6	Fe-S oxidoreductase
FRZ59_17375	ENOG4105DF6	Fe-S oxidoreductase
FRZ59_17385	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
FRZ59_17390	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
FRZ59_17395	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
FRZ59_17400	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
FRZ59_17410	ENOG4105C6E	dna polymerase iii
FRZ59_17435	ENOG4105CBC	glutamate synthase
FRZ59_17445	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FRZ59_17450	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FRZ59_17455	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
FRZ59_17460	ENOG4108YBP	pseudouridine synthase
FRZ59_17475	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FRZ59_17485	ENOG4105C5I	Dehydrogenase
FRZ59_17505	ENOG4105CHR	reductase
FRZ59_17510	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
FRZ59_17535	ENOG4108IUX	(ABC) transporter
FRZ59_17540	ENOG4105RHA	ABC transporter, permease
FRZ59_17555	ENOG4105BZU	Histidine kinase
FRZ59_17575	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FRZ59_17580	ENOG4108Q9V	regulatoR
FRZ59_17585	ENOG4105BZU	Histidine kinase
FRZ59_17595	ENOG4105CJ2	(LipO)protein
FRZ59_17600	ENOG4107YWA	deoxycytidylate deaminase
FRZ59_17610	ENOG4105BZ1	(ABC) transporter
FRZ59_17615	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FRZ59_17645	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
FRZ59_17655	ENOG41074B2	UPF0747 protein
FRZ59_17670	ENOG4105C3F	Signal peptidase i
FRZ59_17675	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
FRZ59_17685	ENOG4105FA0	parb-like partition protein
FRZ59_17690	ENOG4107QJE	Chromosome Partitioning Protein
FRZ59_17695	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
FRZ59_17730	ENOG4107RUZ	Sss sodium solute transporter superfamily
FRZ59_17745	ENOG4105DQ6	Transposase
FRZ59_17845	ENOG4105C27	TonB-dependent Receptor Plug
FRZ59_17895	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
FRZ59_17905	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
FRZ59_17910	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FRZ59_17920	ENOG4105C5H	ABC transporter
FRZ59_17940	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
FRZ59_17950	ENOG4105N5T	Radical SAM Protein
FRZ59_17955	ENOG4105D5P	Methylmalonyl-coA mutase
FRZ59_17960	ENOG4105E4P	ATPase (AAA
FRZ59_17970	ENOG4105HCZ	
FRZ59_17975	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FRZ59_17980	ENOG4105CFG	Acts as a chaperone (By similarity)
FRZ59_17985	ENOG4108ZT0	50S ribosomal protein l17
FRZ59_17990	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FRZ59_17995	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
FRZ59_18000	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
FRZ59_18005	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FRZ59_18010	ENOG410864M	50S ribosomal protein L36
FRZ59_18015	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
FRZ59_18025	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
FRZ59_18030	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
FRZ59_18035	ENOG41084HK	50S ribosomal protein L30
FRZ59_18040	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
FRZ59_18045	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
FRZ59_18050	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
FRZ59_18055	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
FRZ59_18060	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
FRZ59_18065	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FRZ59_18070	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
FRZ59_18075	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
FRZ59_18080	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
FRZ59_18085	ENOG4105WNB	50s ribosomal protein l29
FRZ59_18090	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
FRZ59_18095	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
FRZ59_18100	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
FRZ59_18105	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
FRZ59_18110	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FRZ59_18115	ENOG41081DX	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
FRZ59_18120	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FRZ59_18125	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FRZ59_18130	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
FRZ59_18135	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FRZ59_18140	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
FRZ59_18145	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
FRZ59_18155	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FRZ59_18170	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
FRZ59_18185	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
FRZ59_18190	ENOG4105CK5	oxidoreductase
FRZ59_18195	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
FRZ59_18200	ENOG4105CMR	udp-glucose 4-epimerase
FRZ59_18205	ENOG4108IAJ	Nad-dependent epimerase dehydratase
FRZ59_18210	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
FRZ59_18220	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
FRZ59_18235	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FRZ59_18240	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FRZ59_18250	ENOG4105HDK	L-asparaginase
FRZ59_18255	ENOG4105F8V	Hydrolase, tatD family
FRZ59_18260	ENOG4108V1T	peptidylprolyl cis-trans isomerase
FRZ59_18265	ENOG4105SFS	phosphoesterase RecJ domain protein
FRZ59_18270	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
FRZ59_18280	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FRZ59_18290	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
FRZ59_18295	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
FRZ59_18305	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
FRZ59_18310	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
FRZ59_18375	ENOG4105HA9	of methanol dehydrogenase type
FRZ59_18405	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor