locus-tag	class	description
FK178_00015	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
FK178_00020	ENOG4105DJV	ribulose-phosphate 3-epimerase
FK178_00040	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FK178_00045	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
FK178_00050	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
FK178_00055	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
FK178_00060	ENOG4105D2N	Aldolase
FK178_00080	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FK178_00085	ENOG4105C1A	potassium transporter peripheral membrane
FK178_00090	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
FK178_00095	ENOG4108JQC	penicillin-binding protein 1A
FK178_00100	ENOG4105CHM	Aminotransferase
FK178_00115	ENOG4108Z9Z	response to DNA damage stimulus
FK178_00145	ENOG4105NWN	ApaG protein
FK178_00160	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FK178_00165	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FK178_00170	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FK178_00175	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FK178_00180	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
FK178_00195	ENOG4105CJ2	(LipO)protein
FK178_00200	ENOG4108M6P	methyltransferase
FK178_00225	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
FK178_00255	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
FK178_00275	ENOG4105CSV	Glutaminase
FK178_00280	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
FK178_00305	ENOG4108CSZ	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
FK178_00315	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
FK178_00345	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
FK178_00350	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
FK178_00355	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
FK178_00370	ENOG4105EGD	dinuclear metal center protein, YbgI family
FK178_00375	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
FK178_00380	ENOG4105BZU	Histidine kinase
FK178_00385	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FK178_00400	ENOG4107QJZ	Glycosyl transferase, family 2
FK178_00415	ENOG4107R0I	Cell wall formation (By similarity)
FK178_00420	ENOG4105CHM	Aminotransferase
FK178_00435	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
FK178_00445	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
FK178_00450	ENOG4105KNE	Phosphatidate cytidylyltransferase
FK178_00460	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
FK178_00465	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
FK178_00470	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
FK178_00480	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
FK178_00485	ENOG41062IR	nudix hydrolase
FK178_00495	ENOG4105D05	Receptor
FK178_00500	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
FK178_00505	ENOG4105CPF	Cell wall formation (By similarity)
FK178_00515	ENOG4105C34	Pseudouridine synthase
FK178_00520	ENOG4105D1Q	UPF0246 protein
FK178_00540	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
FK178_00545	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
FK178_00550	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
FK178_00555	ENOG4105DK0	Indole-3-glycerol phosphate synthase
FK178_00560	ENOG4107RI6	Anthranilate phosphoribosyltransferase
FK178_00565	ENOG4105DDQ	anthranilate synthase
FK178_00570	ENOG4105CRQ	synthase (Component I)
FK178_00585	ENOG41082J7	Rhodanese domain protein
FK178_00590	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
FK178_00605	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
FK178_00610	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
FK178_00615	ENOG4105E82	cytochrome subunit of dehydrogenase
FK178_00635	ENOG4105F38	ABC transporter, permease
FK178_00640	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FK178_00645	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
FK178_00670	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
FK178_00675	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FK178_00680	ENOG4108I0Z	Aconitate hydratase
FK178_00685	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FK178_00730	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
FK178_00735	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
FK178_00745	ENOG4105VEJ	Heat shock protein
FK178_00760	ENOG4108IUS	Transketolase
FK178_00770	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
FK178_00785	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
FK178_00790	ENOG4105CDU	Replicative dna helicase
FK178_00800	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
FK178_00805	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
FK178_00810	ENOG4105VJV	50s ribosomal protein L35
FK178_00815	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
FK178_00820	ENOG4105C22	threonyL-tRNA synthetase
FK178_00875	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
FK178_00880	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
FK178_00900	ENOG4105C0H	protease
FK178_00905	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
FK178_00915	ENOG4105HHA	aminodeoxychorismate lyase
FK178_00925	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
FK178_00935	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
FK178_00945	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
FK178_00950	ENOG4108TZV	Membrane
FK178_00960	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
FK178_00965	ENOG4108MJ3	acetyltransferase
FK178_00970	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FK178_00975	ENOG4108URH	decarboxylase
FK178_00985	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
FK178_00990	ENOG4105CGH	5'-nucleotidase
FK178_01010	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
FK178_01035	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
FK178_01040	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
FK178_01075	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
FK178_01080	ENOG4105EYW	Ion transport protein
FK178_01085	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
FK178_01090	ENOG4105DFA	alanine racemase domain protein
FK178_01100	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
FK178_01105	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
FK178_01110	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
FK178_01120	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
FK178_01140	ENOG4107RCM	Releases the N-terminal proline from various substrates (By similarity)
FK178_01145	ENOG4105KY5	gCN5-related N-acetyltransferase
FK178_01150	ENOG4108YZ3	Glyoxalase Bleomycin resistance protein (Dioxygenase
FK178_01160	ENOG4107YZP	Rhodanese domain protein
FK178_01180	ENOG4108TKW	Glyoxalase Bleomycin resistance protein (Dioxygenase
FK178_01200	ENOG4105CKU	formyltetrahydrofolate synthetase
FK178_01210	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
FK178_01220	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
FK178_01235	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
FK178_01240	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
FK178_01275	ENOG4105C27	TonB-dependent Receptor Plug
FK178_01290	ENOG4107URF	beta-phospho-glucomutase
FK178_01300	ENOG4108IUK	alpha amylase, catalytic
FK178_01305	ENOG4105CJQ	hydrolase, family 31
FK178_01310	ENOG4107T9C	Alpha amylase catalytic region
FK178_01315	ENOG4105CG3	alpha amylase, catalytic region
FK178_01320	ENOG4105CTQ	phosphohexokinase
FK178_01325	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
FK178_01335	ENOG4105C0P	Mg chelatase subunit ChlI
FK178_01345	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
FK178_01350	ENOG4105E7W	lamb ycsf family protein
FK178_01355	ENOG4105P4J	Allophanate hydrolase, subunit 1
FK178_01390	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
FK178_01400	ENOG4105CDH	Citrulline--aspartate ligase
FK178_01405	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
FK178_01410	ENOG4105C8Y	Acetylornithine aminotransferase
FK178_01415	ENOG4107REN	Carbamoyltransferase
FK178_01420	ENOG4107T6X	nag kinase
FK178_01425	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
FK178_01430	ENOG4105CH7	arginosuccinase
FK178_01435	ENOG4105C01	Dihydroxy-acid dehydratase
FK178_01440	ENOG4105C7K	acetolactate synthase
FK178_01450	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
FK178_01460	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
FK178_01465	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FK178_01470	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
FK178_01475	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
FK178_01485	ENOG4105UQX	Mate efflux family protein
FK178_01495	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
FK178_01515	ENOG4105CFG	Acts as a chaperone (By similarity)
FK178_01520	ENOG4105K3M	)-transporter
FK178_01530	ENOG4105KA0	thioesterase Superfamily protein
FK178_01545	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
FK178_01555	ENOG4105QNR	S1 RNA binding domain protein
FK178_01580	ENOG4105CPP	Dehydrogenase, E1 component
FK178_01590	ENOG4108URH	decarboxylase
FK178_01595	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FK178_01620	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
FK178_01625	ENOG4107QKV	phosphomannomutase
FK178_01645	ENOG4107QX9	Thiol disulfide interChange protein
FK178_01665	ENOG4105D64	Mechanosensitive ion channel
FK178_01670	ENOG4108RMU	ferritin dps family protein
FK178_01685	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
FK178_01705	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
FK178_01710	ENOG4108IAJ	Nad-dependent epimerase dehydratase
FK178_01720	ENOG4107QQG	Dehydrogenase
FK178_01725	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
FK178_01740	ENOG4105C5E	polysaccharide biosynthesis protein
FK178_01755	ENOG4105CHR	reductase
FK178_01760	ENOG4107TY6	Acylneuraminate cytidylyltransferase
FK178_01775	ENOG4105D2T	synthase
FK178_01795	ENOG4105K64	Glycosyl transferase, family 2
FK178_01800	ENOG4107UVV	polysaccharide deacetylase
FK178_01820	ENOG4105CG5	Glycosyl transferase (Group 1
FK178_01840	ENOG4105CAQ	asparagine synthetase
FK178_01850	ENOG4107VDP	teichoic acid biosynthesis
FK178_01855	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
FK178_01880	ENOG4105D3Q	Sugar transferase
FK178_01885	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
FK178_01890	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
FK178_01920	ENOG4105BZU	Histidine kinase
FK178_01935	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
FK178_02000	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
FK178_02005	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
FK178_02010	ENOG4105II7	pyrroline-5-carboxylate reductase
FK178_02035	ENOG4105DGW	oligopeptidase A
FK178_02040	ENOG4105BZU	Histidine kinase
FK178_02045	ENOG4105BZU	Histidine kinase
FK178_02065	ENOG4105BZU	Histidine kinase
FK178_02070	ENOG4108R99	pseudouridine synthase
FK178_02080	ENOG4105DF9	Lipoate-protein, ligase
FK178_02090	ENOG4105CY0	Metallo-Beta-Lactamase
FK178_02130	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
FK178_02145	ENOG4105DHJ	ABC, transporter
FK178_02150	ENOG4105CY3	ABC transporter, permease
FK178_02175	ENOG4105E2A	Dehydrogenase
FK178_02200	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
FK178_02205	ENOG4105BZS	acriflavin resistance protein
FK178_02215	ENOG4105CFP	Peptidase U32
FK178_02245	ENOG4108VCT	Sulfite exporter TauE/SafE
FK178_02250	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
FK178_02260	ENOG4105NQN	cytochrome C
FK178_02265	ENOG4105CGH	5'-nucleotidase
FK178_02290	ENOG4105EU0	Major facilitator Superfamily
FK178_02295	ENOG4107TPS	domain protein
FK178_02330	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
FK178_02340	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FK178_02395	ENOG4108I0Y	(ABC) transporter
FK178_02400	ENOG4108UJV	acyl-CoA thioesterase i
FK178_02405	ENOG4107QJZ	Glycosyl transferase, family 2
FK178_02420	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
FK178_02425	ENOG4105BZU	Histidine kinase
FK178_02430	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FK178_02435	ENOG4105CGK	Exodeoxyribonuclease III
FK178_02450	ENOG4105E2X	shikimate dehydrogenase
FK178_02455	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FK178_02460	ENOG4105BZU	Histidine kinase
FK178_02465	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
FK178_02485	ENOG4105CGZ	zinc metallopeptidase
FK178_02495	ENOG41066YJ	Beta-lactamase
FK178_02505	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
FK178_02510	ENOG4108JYZ	YitT family
FK178_02515	ENOG4105D6J	arsenicaL-resistance protein
FK178_02525	ENOG41089UC	methyltransferase, type 11
FK178_02555	ENOG4108IXY	short-chain dehydrogenase reductase
FK178_02560	ENOG4105C26	Dehydrogenase
FK178_02580	ENOG4105JAB	phenazine biosynthesis protein, phzf family
FK178_02595	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
FK178_02620	ENOG4105VZ8	Transcriptional regulator
FK178_02670	ENOG4105CBS	Chea signal transduction histidine kinase
FK178_02710	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FK178_02795	ENOG4107QMH	DNA methylase
FK178_02800	ENOG4105C0D	helicase
FK178_02805	ENOG4106K8T	Toxic component of a toxin-antitoxin (TA) module. A stable (half-life 27.6 minutes) endoribonuclease that in the absence of cognate antitoxin RnlB causes generalized RNA degradation. Degrades late enterobacteria phage T4 mRNAs, protecting the host against T4 reproduction. Activity is inhibited by cognate antitoxin RnlB and by enterobacteria phage T4 protein Dmd. Targets cyaA mRNA
FK178_02870	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FK178_02875	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
FK178_02910	ENOG4105C9A	Phoh family
FK178_02915	ENOG4107QWK	SAICAR synthetase
FK178_02920	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
FK178_03000	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
FK178_03015	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
FK178_03020	ENOG4105C8Y	Acetylornithine aminotransferase
FK178_03025	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
FK178_03040	ENOG4105C1J	atp-dependent rna helicase
FK178_03045	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
FK178_03050	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
FK178_03055	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
FK178_03060	ENOG4107U9T	Pfam:Ribonuclease_BN
FK178_03075	ENOG4105C25	Primosomal protein n'
FK178_03080	ENOG4108NEV	two component transcriptional regulator, LytTR family
FK178_03085	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
FK178_03090	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
FK178_03095	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
FK178_03110	ENOG4105CUT	histidyl-tRNA synthetase
FK178_03145	ENOG4105C3J	Cysteine desulfurase
FK178_03170	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
FK178_03180	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FK178_03205	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
FK178_03215	ENOG4107QN2	dihydrolipoyl dehydrogenase
FK178_03225	ENOG4105E0X	reductase
FK178_03230	ENOG4105E0X	reductase
FK178_03245	ENOG4105DEU	major facilitator superfamily
FK178_03265	ENOG4105EMN	RNA polymerase sigma factor
FK178_03270	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
FK178_03280	ENOG4105CAT	Cytidine monophosphate kinase
FK178_03290	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
FK178_03295	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
FK178_03300	ENOG4105CXT	aspartate transcarbamylase
FK178_03310	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
FK178_03315	ENOG4105K4I	Scp-like extracellular
FK178_03320	ENOG4105UYK	outer membrane protein a
FK178_03335	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
FK178_03345	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
FK178_03360	ENOG4105C6E	dna polymerase iii
FK178_03395	ENOG410836F	Transposase
FK178_03435	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
FK178_03440	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
FK178_03445	ENOG4108RKS	Short-chain dehydrogenase reductase Sdr
FK178_03480	ENOG4108Z03	MAF-like protein
FK178_03490	ENOG4105KPY	Small multidrug resistance protein
FK178_03505	ENOG4105CRE	cytochrome C
FK178_03510	ENOG4105C9Q	fumarate hydratase class II
FK178_03530	ENOG4105K89	arsenate reductase
FK178_03550	ENOG41080WS	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
FK178_03555	ENOG4105CUG	Oligopeptidase b
FK178_03565	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FK178_03600	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
FK178_03610	ENOG4105CSM	endonuclease III
FK178_03625	ENOG4105DCF	alanine dehydrogenase
FK178_03635	ENOG4105K8N	protein family UPF0079, ATPase
FK178_03640	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FK178_03645	ENOG4105DCI	Phosphohydrolase
FK178_03655	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FK178_03660	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FK178_03665	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
FK178_03670	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FK178_03680	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
FK178_03685	ENOG4105CHR	reductase
FK178_03700	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
FK178_03705	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
FK178_03710	ENOG4105CIH	Imidazole acetol-phosphate transaminase
FK178_03715	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
FK178_03720	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
FK178_03725	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
FK178_03730	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
FK178_03735	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
FK178_03745	ENOG4105EUB	pirin domain protein
FK178_03775	ENOG41076HS	cation diffusion facilitator family transporter
FK178_03805	ENOG4105CH6	catalase
FK178_03815	ENOG4108STX	response regulator
FK178_03820	ENOG4105BZU	Histidine kinase
FK178_03840	ENOG4108IGT	Dipeptidase
FK178_03845	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FK178_03860	ENOG4108Z9K	Osmotically inducible protein
FK178_03865	ENOG4108YZY	peptidylprolyl cis-trans isomerase
FK178_03870	ENOG4105D9R	oxidoreductase
FK178_03885	ENOG4105GR3	Histidine kinase
FK178_03890	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FK178_03895	ENOG410841Q	phosphoesterase PA-phosphatase related protein
FK178_03915	ENOG4105CFH	Aspartokinase
FK178_03930	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FK178_03935	ENOG4105NQG	DoxX
FK178_03945	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
FK178_03965	ENOG41081QV	Universal stress protein
FK178_03985	ENOG4105C1J	atp-dependent rna helicase
FK178_03990	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
FK178_04010	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
FK178_04015	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FK178_04030	ENOG4105FDR	Membrane
FK178_04040	ENOG4107QHQ	amino acid
FK178_04070	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
FK178_04075	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FK178_04080	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FK178_04085	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FK178_04090	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
FK178_04095	ENOG41065KQ	synthase
FK178_04105	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
FK178_04110	ENOG4108ZG0	Ompa motb domain protein
FK178_04125	ENOG4105CPP	Dehydrogenase, E1 component
FK178_04145	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
FK178_04150	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
FK178_04165	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
FK178_04170	ENOG4105C98	muts2 protein
FK178_04175	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
FK178_04180	ENOG4105CK2	sodium dicarboxylate symporter
FK178_04185	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
FK178_04200	ENOG4105CQB	FAD linked oxidase domain protein
FK178_04215	ENOG4105D17	glycoside hydrolase, family 3 domain protein
FK178_04225	ENOG4105DF6	Fe-S oxidoreductase
FK178_04230	ENOG4105DF6	Fe-S oxidoreductase
FK178_04240	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
FK178_04255	ENOG4108Z5K	methylglyoxal synthase
FK178_04260	ENOG4105CTQ	phosphohexokinase
FK178_04270	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FK178_04300	ENOG4105D9U	N-acetyltransferase
FK178_04310	ENOG4105NAE	bifunctional deaminase-reductase domain protein
FK178_04335	ENOG4107QJZ	Glycosyl transferase, family 2
FK178_04340	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
FK178_04360	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FK178_04365	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FK178_04395	ENOG4105CHR	reductase
FK178_04420	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FK178_04455	ENOG4105CHC	glucokinase (EC 2.7.1.2)
FK178_04470	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
FK178_04475	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
FK178_04495	ENOG4105BZU	Histidine kinase
FK178_04500	ENOG4105BZU	Histidine kinase
FK178_04515	ENOG4105D7Z	glutathione synthase
FK178_04535	ENOG4105CG3	alpha amylase, catalytic region
FK178_04540	ENOG4105CG3	alpha amylase, catalytic region
FK178_04555	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
FK178_04560	ENOG4105D7N	magnesium and cobalt transport protein CorA
FK178_04565	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FK178_04570	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FK178_04575	ENOG4105CFI	type iii restriction protein res subunit
FK178_04580	ENOG4105IJJ	transcriptional regulator, crp fnr family
FK178_04590	ENOG4105C6T	cysteine synthase
FK178_04595	ENOG4105D7W	serine acetyltransferase
FK178_04605	ENOG4105EM2	membrane
FK178_04610	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
FK178_04620	ENOG4105CHR	reductase
FK178_04640	ENOG4105C1J	atp-dependent rna helicase
FK178_04650	ENOG4105CMR	udp-glucose 4-epimerase
FK178_04655	ENOG4105VCH	membrane
FK178_04660	ENOG4105CUY	Mechanosensitive ion channel
FK178_04705	ENOG4105CTJ	Metal Dependent Phosphohydrolase
FK178_04710	ENOG4105CHU	acetyl-coa acetyltransferase
FK178_04720	ENOG4108PPB	Seems to be required for the assembly of the photosystem I complex (By similarity)
FK178_04725	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FK178_04740	ENOG4105C84	Histidine ammonia-lyase
FK178_04745	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
FK178_04750	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
FK178_04760	ENOG4105KZX	Pterin carbinolamine dehydratase
FK178_04765	ENOG4105CDY	transcriptional regulatory protein
FK178_04780	ENOG4105D49	3-dehydroquinate synthase
FK178_04790	ENOG4108Z0Z	intracellular protease Pfpi family
FK178_04825	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
FK178_04840	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
FK178_04845	ENOG4105C3G	gtp-binding protein
FK178_04855	ENOG4105C6K	Malic enzyme
FK178_04860	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
FK178_04885	ENOG4107SBB	4-alpha-glucanotransferase (EC 2.4.1.25)
FK178_04905	ENOG4107S9Q	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
FK178_04915	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
FK178_04920	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
FK178_04930	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
FK178_04935	ENOG4108JQ1	Dehydrogenase
FK178_04955	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
FK178_04965	ENOG4105EUJ	GTP cyclohydrolase i
FK178_04970	ENOG4107V8H	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
FK178_04980	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
FK178_04990	ENOG4105BZU	Histidine kinase
FK178_04995	ENOG4105BZU	Histidine kinase
FK178_05005	ENOG4105CD3	dihydroorotase
FK178_05025	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
FK178_05035	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
FK178_05055	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FK178_05060	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
FK178_05070	ENOG4108UJU	UPF0301 protein
FK178_05075	ENOG4105F0I	Aminotransferase
FK178_05100	ENOG4105S64	Formate nitrite transporter
FK178_05115	ENOG4107ZSV	Receptor
FK178_05125	ENOG4105D8V	Glucose sorbosone dehydrogenase
FK178_05135	ENOG4108ZMR	Ion transport 2 domain-containing protein
FK178_05170	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FK178_05180	ENOG4105CY0	Metallo-Beta-Lactamase
FK178_05200	ENOG4108YZA	Nitrogen regulatory protein pii
FK178_05235	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
FK178_05260	ENOG4108IJF	Heavy metal efflux pump, CzcA
FK178_05315	ENOG4105E3B	Multicopper oxidase
FK178_05355	ENOG41082YX	Transcriptional regulator, arsr family
FK178_05420	ENOG4105CUB	amino acid
FK178_05425	ENOG4107QN2	dihydrolipoyl dehydrogenase
FK178_05445	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
FK178_05490	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
FK178_05570	ENOG4105W5Q	DNA repair protein (RadC
FK178_05575	ENOG4108UUM	single-stranded DNA-binding protein
FK178_05600	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FK178_05635	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
FK178_05640	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
FK178_05655	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
FK178_05660	ENOG4107QTF	adenylosuccinate lyase
FK178_05695	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
FK178_05705	ENOG4105EHG	Permease protein
FK178_05710	ENOG4105E0A	ABC, transporter
FK178_05715	ENOG4105CGY	Dna recombination protein
FK178_05735	ENOG4105DHU	Bile acid
FK178_05740	ENOG4105M08	Membrane
FK178_05750	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
FK178_05755	ENOG4105VG0	50S ribosomal protein l34
FK178_05785	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FK178_05795	ENOG41081WG	50s ribosomal protein l31
FK178_05805	ENOG4105CKK	Glycosyl transferase, family 2
FK178_05815	ENOG4105BZ1	(ABC) transporter
FK178_05820	ENOG4105EMN	RNA polymerase sigma factor
FK178_05840	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
FK178_05855	ENOG4108IQE	Amp-dependent synthetase and ligase
FK178_05860	ENOG4105CPC	Aldo Keto reductase
FK178_05880	ENOG4105CHU	acetyl-coa acetyltransferase
FK178_05885	ENOG4105C1G	acyl-Coa dehydrogenase
FK178_05890	ENOG4105BZP	glycoside hydrolase 15-related
FK178_05940	ENOG4105C27	TonB-dependent Receptor Plug
FK178_05985	ENOG4105EAA	nucleoside
FK178_06015	ENOG4105K6V	RNA polymerase
FK178_06045	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
FK178_06075	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FK178_06085	ENOG4105C5Q	Transcriptional regulator
FK178_06130	ENOG4105C3M	thioredoxin reductase
FK178_06135	ENOG4105EN6	Membrane
FK178_06150	ENOG4107QX3	carboxylase
FK178_06155	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FK178_06165	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
FK178_06180	ENOG41087NI	Sulfite exporter TauE/SafE
FK178_06190	ENOG4108UT2	hemolysin iii
FK178_06200	ENOG4107RH8	nuclease SbcCD subunit D
FK178_06205	ENOG4105EYH	Exonuclease
FK178_06215	ENOG4108JQ1	Dehydrogenase
FK178_06220	ENOG4105D8V	Glucose sorbosone dehydrogenase
FK178_06225	ENOG4105BZU	Histidine kinase
FK178_06230	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FK178_06235	ENOG4108793	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
FK178_06265	ENOG4105DH4	Periplasmic copper-binding protein
FK178_06280	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
FK178_06285	ENOG4108IYU	L-aspartate oxidase
FK178_06295	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
FK178_06300	ENOG4108RAV	Conserved protein
FK178_06315	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
FK178_06320	ENOG4108YYC	ycei family
FK178_06335	ENOG4105KCV	RNA signal recognition particle 4.5S RNA
FK178_06370	ENOG410836F	Transposase
FK178_06420	ENOG4105D05	Receptor
FK178_06430	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
FK178_06445	ENOG4107QJZ	Glycosyl transferase, family 2
FK178_06475	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
FK178_06480	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FK178_06490	ENOG4105D8V	Glucose sorbosone dehydrogenase
FK178_06495	ENOG4107TJ9	Cytochrome
FK178_06500	ENOG4105DBI	uridine monophosphokinase
FK178_06510	ENOG4105CMN	Methylmalonyl-coA mutase
FK178_06515	ENOG4105D5P	Methylmalonyl-coA mutase
FK178_06520	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
FK178_06525	ENOG4107QJE	Chromosome Partitioning Protein
FK178_06530	ENOG4105FA0	parb-like partition protein
FK178_06540	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
FK178_06545	ENOG4105C3F	Signal peptidase i
FK178_06570	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
FK178_06580	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
FK178_06590	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
FK178_06605	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
FK178_06615	ENOG4105SFS	phosphoesterase RecJ domain protein
FK178_06625	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
FK178_06630	ENOG4105CIN	aminoacyl-histidine dipeptidase
FK178_06640	ENOG4105CD3	dihydroorotase
FK178_06650	ENOG4108RWN	rrna methyltransferase
FK178_06655	ENOG4105C2Y	STE24 endopeptidase EC 3.4.24.84
FK178_06665	ENOG41090R7	Ferric uptake
FK178_06670	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
FK178_06690	ENOG4105C8Y	Acetylornithine aminotransferase
FK178_06710	ENOG4105E2X	shikimate dehydrogenase
FK178_06730	ENOG4105DXN	mazG family
FK178_06745	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
FK178_06755	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
FK178_06780	ENOG4107SBE	Glycosyl transferase (Group 1
FK178_06785	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
FK178_06790	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
FK178_06795	ENOG4107SF2	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
FK178_06815	ENOG4105CJ1	ABC, transporter
FK178_06835	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
FK178_06845	ENOG4105VN1	Heat shock protein
FK178_06850	ENOG4105EXU	Membrane
FK178_06875	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
FK178_06880	ENOG4105CRQ	synthase (Component I)
FK178_06900	ENOG4107QN2	dihydrolipoyl dehydrogenase
FK178_06910	ENOG4105J0Q	Transcriptional regulator
FK178_06920	ENOG4105DFD	Na H antiporter
FK178_06925	ENOG4105D3R	alkyl hydroperoxide reductase
FK178_06940	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
FK178_06950	ENOG4105CNU	cell division protein FtsK
FK178_06965	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
FK178_06975	ENOG4108UB4	uncharacterized protein ygjQ
FK178_06985	ENOG4108HCJ	Hydrolase
FK178_07000	ENOG4105VEQ	Cold shock protein
FK178_07015	ENOG4105DZ0	fad dependent oxidoreductase
FK178_07025	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
FK178_07030	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
FK178_07045	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
FK178_07050	ENOG4105EA8	2-Nitropropane dioxygenase
FK178_07070	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FK178_07080	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
FK178_07085	ENOG4105C27	TonB-dependent Receptor Plug
FK178_07095	ENOG4108HRK	Histidine kinase
FK178_07105	ENOG4105DY9	regulatoR
FK178_07120	ENOG4105C28	cystathionine
FK178_07125	ENOG4105CI2	imidazolone-5-propionate hydrolase
FK178_07145	ENOG4107T8T	UPF0173 metal-dependent hydrolase
FK178_07160	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
FK178_07180	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
FK178_07185	ENOG4105VDW	Csbd family
FK178_07200	ENOG4105C1J	atp-dependent rna helicase
FK178_07205	ENOG4105C5H	ABC transporter
FK178_07220	ENOG4107QX3	carboxylase
FK178_07250	ENOG4107FCW	Abortive infection protein
FK178_07255	ENOG4105DTQ	mandelate racemase muconate lactonizing
FK178_07260	ENOG4107W2A	UPF0173 metal-dependent hydrolase
FK178_07265	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
FK178_07290	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
FK178_07385	ENOG4105C5H	ABC transporter
FK178_07395	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
FK178_07400	ENOG4105E1F	short-chain dehydrogenase reductase
FK178_07420	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
FK178_07425	ENOG4105VRS	hydrolase family 18
FK178_07430	ENOG4105K6H	D-cysteine desulfhydrase
FK178_07445	ENOG4105CGP	Urocanate hydratase
FK178_07470	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
FK178_07495	ENOG4105HA9	of methanol dehydrogenase type
FK178_07505	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
FK178_07510	ENOG4105CS1	NAD(P)H quinone oxidoreductase
FK178_07530	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
FK178_07550	ENOG4108V1T	peptidylprolyl cis-trans isomerase
FK178_07565	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
FK178_07570	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
FK178_07575	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
FK178_07580	ENOG4105E2Z	phosphate ABC transporter (Permease
FK178_07585	ENOG4105C8U	phosphate abc transporter
FK178_07605	ENOG4105DQ4	alcohol dehydrogenase
FK178_07620	ENOG4108UW5	maltose o-acetyltransferase
FK178_07625	ENOG4105IIU	Aminopeptidase
FK178_07630	ENOG4105DY8	decarboxylase
FK178_07635	ENOG41074B2	UPF0747 protein
FK178_07680	ENOG4105EIE	fructose-bisphosphate aldolase
FK178_07690	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
FK178_07700	ENOG4105F0I	Aminotransferase
FK178_07710	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
FK178_07715	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
FK178_07725	ENOG41083ND	50S ribosomal protein L33
FK178_07730	ENOG4105KDC	50s ribosomal protein l28
FK178_07735	ENOG4105CEV	competence damage-inducible protein
FK178_07745	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
FK178_07760	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
FK178_07765	ENOG4107RJ1	sodium solute
FK178_07780	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FK178_07790	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
FK178_07800	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
FK178_07805	ENOG4105BZU	Histidine kinase
FK178_07845	ENOG410667J	hydrolase
FK178_07870	ENOG4105DG6	mannose-6-phosphate isomerase
FK178_07875	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
FK178_07890	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
FK178_07920	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FK178_07925	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FK178_07930	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
FK178_07935	ENOG4107VNI	ribosomal protein l10
FK178_07940	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
FK178_07945	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
FK178_07965	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
FK178_07995	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FK178_08000	ENOG41083X6	30S ribosomal protein S21
FK178_08005	ENOG4105C1G	acyl-Coa dehydrogenase
FK178_08015	ENOG4105BZG	amino acid carrier protein
FK178_08055	ENOG4107R34	abc transporter permease protein
FK178_08060	ENOG4105EHZ	conserved protein UCP016719
FK178_08075	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
FK178_08085	ENOG4105EFZ	amidohydrolase
FK178_08115	ENOG4105CI3	gtp-binding protein typa
FK178_08125	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
FK178_08150	ENOG4105C27	TonB-dependent Receptor Plug
FK178_08160	ENOG4105BZU	Histidine kinase
FK178_08175	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FK178_08200	ENOG4108YYC	ycei family
FK178_08215	ENOG4108YYC	ycei family
FK178_08225	ENOG4105EUB	pirin domain protein
FK178_08250	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
FK178_08255	ENOG4105VIE	preprotein translocase, subunit YajC
FK178_08265	ENOG4107R6T	Involved in the transcription termination process (By similarity)
FK178_08275	ENOG4105BZ1	(ABC) transporter
FK178_08300	ENOG4105CNM	Receptor
FK178_08305	ENOG4108Z7R	Chaperone CsaA
FK178_08320	ENOG4105D3R	alkyl hydroperoxide reductase
FK178_08330	ENOG4105C9U	ATP-dependent DNA helicase RecQ
FK178_08335	ENOG4105C2X	Arabinose 5-phosphate isomerase
FK178_08340	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
FK178_08345	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
FK178_08355	ENOG4108IUZ	ABC transporter
FK178_08360	ENOG4105WDY	DNA (cytosine-5-)-methyltransferase
FK178_08370	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
FK178_08380	ENOG4107SBE	Glycosyl transferase (Group 1
FK178_08385	ENOG4107T8Q	Glycosyl transferase (Group 1
FK178_08445	ENOG4108JQ1	Dehydrogenase
FK178_08450	ENOG4105F0R	Cytidylyltransferase
FK178_08465	ENOG4105D2T	synthase
FK178_08480	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
FK178_08495	ENOG4105K64	Glycosyl transferase, family 2
FK178_08500	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
FK178_08505	ENOG4107S6X	Glycosyl transferase, family 2
FK178_08530	ENOG4105C30	Nad-dependent epimerase dehydratase
FK178_08535	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
FK178_08560	ENOG4105EY8	ABC transporter
FK178_08575	ENOG4105C27	TonB-dependent Receptor Plug
FK178_08585	ENOG4107RAN	Peptidase, M16
FK178_08610	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FK178_08625	ENOG4105C30	Nad-dependent epimerase dehydratase
FK178_08630	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
FK178_08640	ENOG4105D75	Capsular exopolysaccharide family
FK178_08660	ENOG4105C5H	ABC transporter
FK178_08675	ENOG4105C19	ABC transporter
FK178_08695	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
FK178_08730	ENOG4108ZHJ	Organic hydroperoxide resistance protein
FK178_08740	ENOG4108IAJ	Nad-dependent epimerase dehydratase
FK178_08775	ENOG4105CSR	polyphosphate kinase 2
FK178_08795	ENOG4105EGS	Mechanosensitive ion channel
FK178_08800	ENOG4105RHA	ABC transporter, permease
FK178_08805	ENOG4108IUX	(ABC) transporter
FK178_08810	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FK178_08815	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
FK178_08825	ENOG4105ECP	epimerase
FK178_08830	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
FK178_08840	ENOG4105CM2	brancheD-chain amino acid aminotransferase
FK178_08865	ENOG4105WMR	Protein CrcB homolog
FK178_08885	ENOG4105C1J	atp-dependent rna helicase
FK178_08890	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FK178_08895	ENOG410904A	RNA polymerase
FK178_08910	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
FK178_08915	ENOG4105D5P	Methylmalonyl-coA mutase
FK178_08930	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
FK178_08935	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
FK178_08940	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
FK178_08950	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
FK178_08985	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
FK178_09000	ENOG4105E0Y	RtcB Protein
FK178_09005	ENOG4105D9R	oxidoreductase
FK178_09010	ENOG4105BZG	amino acid carrier protein
FK178_09040	ENOG4105IPS	esterase
FK178_09060	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
FK178_09065	ENOG4105CP7	Triose-phosphate isomerase
FK178_09080	ENOG4105EEI	dihydropteroate synthase
FK178_09085	ENOG4105C8B	TIGR00159 family
FK178_09090	ENOG4105BZ1	(ABC) transporter
FK178_09095	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
FK178_09110	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
FK178_09130	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
FK178_09135	ENOG4105WH1	Two component transcriptional regulator luxr family
FK178_09140	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
FK178_09175	ENOG41061MV	Arylsulfatase
FK178_09185	ENOG4105E6M	Sulphatase-modifying factor protein
FK178_09235	ENOG4105CBG	Sulfatase
FK178_09245	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
FK178_09250	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
FK178_09280	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
FK178_09285	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
FK178_09295	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
FK178_09305	ENOG4105CHM	Aminotransferase
FK178_09310	ENOG4105CQC	Prephenate dehydratase
FK178_09330	ENOG4105SYT	Methylenetetrahydrofolate reductase
FK178_09340	ENOG4105C3R	Methionine synthase
FK178_09350	ENOG4105C28	cystathionine
FK178_09355	ENOG4105CFH	Aspartokinase
FK178_09360	ENOG4105DWV	Homoserine O-trans-acetylase
FK178_09370	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
FK178_09375	ENOG4105C1G	acyl-Coa dehydrogenase
FK178_09380	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
FK178_09385	ENOG41081QV	Universal stress protein
FK178_09445	ENOG4105CI2	imidazolone-5-propionate hydrolase
FK178_09460	ENOG4105ZMH	deoxynucleoside kinase
FK178_09475	ENOG4105DQE	DNA ligase
FK178_09480	ENOG4105FDF	Could be involved in DNA repair (By similarity)
FK178_09495	ENOG4105F0N	pyrophosphate phospho-hydrolase
FK178_09510	ENOG4105CPP	Dehydrogenase, E1 component
FK178_09515	ENOG4105BZJ	Electron transfer flavoprotein
FK178_09520	ENOG4105C10	Electron transfer flavoprotein
FK178_09530	ENOG4105D9N	nucleoside
FK178_09535	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
FK178_09550	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
FK178_09575	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
FK178_09590	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
FK178_09630	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
FK178_09635	ENOG4105C0B	DNA polymerase III (alpha subunit)
FK178_09660	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FK178_09665	ENOG4105BZU	Histidine kinase
FK178_09780	ENOG4105NVB	glycoside hydrolase, family 19
FK178_09795	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
FK178_09810	ENOG4105C3M	thioredoxin reductase
FK178_09825	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FK178_09865	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
FK178_09870	ENOG4105CHH	sulfate transporter
FK178_09900	ENOG4108Z0R	Transferase
FK178_09905	ENOG4107ZYR	domain protein
FK178_09910	ENOG4105CZN	Potassium uptake protein
FK178_09955	ENOG4105C5H	ABC transporter
FK178_09985	ENOG4105E6M	Sulphatase-modifying factor protein
FK178_10005	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
FK178_10010	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FK178_10030	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
FK178_10040	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
FK178_10085	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
FK178_10095	ENOG4107V87	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity)
FK178_10100	ENOG41086DT	Membrane protein of unknown function
FK178_10115	ENOG4105EV9	Alpha Beta Hydrolase
FK178_10120	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
FK178_10130	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
FK178_10140	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
FK178_10160	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
FK178_10185	ENOG4105D64	Mechanosensitive ion channel
FK178_10190	ENOG41072GX	Peptidase M22 Glycoprotease
FK178_10195	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
FK178_10210	ENOG4108SJC	Membrane
FK178_10215	ENOG4108KF3	Electron transport protein SCO1 SenC
FK178_10235	ENOG4105CCU	oxidase (Subunit III)
FK178_10240	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
FK178_10270	ENOG4108YYC	ycei family
FK178_10280	ENOG4105DY9	regulatoR
FK178_10290	ENOG4107R4J	Chloride channel
FK178_10300	ENOG4105FQP	Beta-lactamase
FK178_10330	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
FK178_10340	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
FK178_10345	ENOG4105C6K	Malic enzyme
FK178_10355	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
FK178_10370	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
FK178_10375	ENOG4105BZ9	Cytochrome C oxidase, subunit I
FK178_10405	ENOG4107SFQ	iron-sulfur binding
FK178_10420	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
FK178_10425	ENOG4105CHV	Transcription elongation factor NusA
FK178_10430	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
FK178_10435	ENOG4107YZX	Universal stress protein
FK178_10460	ENOG4105BZU	Histidine kinase
FK178_10465	ENOG4105M3Z	response regulator
FK178_10490	ENOG4105C59	p-type ATPase
FK178_10495	ENOG4107XVH	Transcriptional regulator
FK178_10505	ENOG4107QM5	aconitate hydratase
FK178_10540	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
FK178_10545	ENOG4105C58	cytochrome c oxidase accessory protein ccog
FK178_10575	ENOG4105CYC	Transferase
FK178_10585	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
FK178_10600	ENOG4105D4P	Coproporphyrinogen iii oxidase
FK178_10620	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
FK178_10630	ENOG4109015	Biopolymer transport protein exbD tolR
FK178_10645	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
FK178_10650	ENOG4105C1G	acyl-Coa dehydrogenase
FK178_10695	ENOG4105C27	TonB-dependent Receptor Plug
FK178_10705	ENOG4105C27	TonB-dependent Receptor Plug
FK178_10710	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FK178_10720	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
FK178_10725	ENOG4105VPI	YqaE family transport protein
FK178_10730	ENOG4105CRK	lysyL-tRNA synthetase
FK178_10755	ENOG4108ZMR	Ion transport 2 domain-containing protein
FK178_10760	ENOG4105C59	p-type ATPase
FK178_10795	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
FK178_10810	ENOG4108IJF	Heavy metal efflux pump, CzcA
FK178_10840	ENOG4105DC1	bifunctional purine biosynthesis protein purh
FK178_10845	ENOG4105DFF	Rod shape-determining protein mreb
FK178_10865	ENOG4105CNI	cell division protein FtsW
FK178_10875	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
FK178_10885	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
FK178_10895	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
FK178_10905	ENOG4105DUX	Transporter
FK178_10910	ENOG4105DUX	Transporter
FK178_10915	ENOG4105C5Z	peptidase
FK178_10920	ENOG4107EEU	hydroxymethylglutaryL-CoA reductase
FK178_10930	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
FK178_10935	ENOG4105C37	(CBS) domain
FK178_10960	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
FK178_10980	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
FK178_10985	ENOG4105BZU	Histidine kinase
FK178_10995	ENOG4105DDG	Cyanophycinase
FK178_11005	ENOG4105C27	TonB-dependent Receptor Plug
FK178_11025	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
FK178_11030	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
FK178_11035	ENOG4108IFG	nitrite reductase, (NAD(P)H)
FK178_11045	ENOG4105C3Q	Glycosyl transferase, family 2
FK178_11050	ENOG4105CND	Glycosyl transferase, family 2
FK178_11065	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
FK178_11090	ENOG4105EIG	urea carboxylase-associated protein 1
FK178_11105	ENOG4105W3H	MtN3 and saliva related transmembrane protein
FK178_11115	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
FK178_11120	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
FK178_11125	ENOG4105CBX	hi0933 family
FK178_11130	ENOG4105KAV	tspo and mbr like protein
FK178_11150	ENOG4105I08	Pseudouridine synthase
FK178_11195	ENOG4105C8T	Leucyl-tRNA synthetase
FK178_11200	ENOG4107RJ9	Cell division protein FtsX
FK178_11210	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
FK178_11215	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
FK178_11225	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
FK178_11230	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
FK178_11240	ENOG4107XWI	flavin reductase domain protein, FMN-binding
FK178_11245	ENOG4105BZU	Histidine kinase
FK178_11260	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
FK178_11275	ENOG4105BZU	Histidine kinase
FK178_11280	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
FK178_11290	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
FK178_11305	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
FK178_11315	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
FK178_11325	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
FK178_11335	ENOG4105K46	50S ribosomal protein l27
FK178_11340	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
FK178_11360	ENOG4108594	Permease of the drug metabolite transporter
FK178_11370	ENOG4105C37	(CBS) domain
FK178_11385	ENOG4105K70	DNA-binding protein
FK178_11390	ENOG4105C03	ribonuclease
FK178_11410	ENOG410902V	Modulates RecA activity (By similarity)
FK178_11425	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
FK178_11430	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FK178_11440	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
FK178_11445	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
FK178_11455	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FK178_11465	ENOG4105KJM	monovalent cation h antiporter subunit g
FK178_11475	ENOG4105SC1	monovalent cation H antiporter subunit E
FK178_11480	ENOG4108JPZ	Monovalent cation H antiporter subunit D
FK178_11485	ENOG4105MKQ	Monovalent cation H antiporter subunit C
FK178_11490	ENOG4108PMQ	Na H antiporter MnhB subunit-related protein
FK178_11495	ENOG4105D65	subunit l
FK178_11500	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
FK178_11505	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
FK178_11510	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
FK178_11520	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
FK178_11525	ENOG4107RWD	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
FK178_11530	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
FK178_11545	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
FK178_11555	ENOG4105CPC	Aldo Keto reductase
FK178_11560	ENOG4105ER2	Ompa motb domain protein
FK178_11565	ENOG4105CGK	Exodeoxyribonuclease III
FK178_11575	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
FK178_11585	ENOG4105MJ2	Competence protein
FK178_11595	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
FK178_11605	ENOG4105CHM	Aminotransferase
FK178_11610	ENOG4105E33	succinate dehydrogenase
FK178_11625	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FK178_11635	ENOG4107RAQ	aminopeptidase
FK178_11640	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
FK178_11645	ENOG4105EV9	Alpha Beta Hydrolase
FK178_11655	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
FK178_11660	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
FK178_11700	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
FK178_11705	ENOG4105VG1	fes assembly suf system protein
FK178_11720	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
FK178_11755	ENOG4105E39	Enoyl-CoA hydratase
FK178_11760	ENOG4108HWS	Histidine kinase
FK178_11775	ENOG4107SF0	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
FK178_11790	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
FK178_11795	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
FK178_11805	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
FK178_11815	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
FK178_11830	ENOG4105D52	delta-aminolevulinic acid dehydratase
FK178_11850	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
FK178_11865	ENOG4105C26	Dehydrogenase
FK178_11875	ENOG4105D44	asparaginase
FK178_11890	ENOG41080ZE	Adenylate cyclase
FK178_11895	ENOG4105K4T	epimerase
FK178_11915	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
FK178_11920	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
FK178_11925	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
FK178_11930	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
FK178_11935	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
FK178_11945	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
FK178_11955	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
FK178_11960	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
FK178_11965	ENOG4105CDV	Ompa motb domain protein
FK178_12005	ENOG4108IPT	Naphthoate synthase
FK178_12015	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
FK178_12020	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
FK178_12025	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
FK178_12040	ENOG4107T8J	thymidine kinase
FK178_12045	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
FK178_12050	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
FK178_12055	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
FK178_12085	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
FK178_12095	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
FK178_12105	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
FK178_12110	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
FK178_12115	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
FK178_12120	ENOG4105WXV	50S ribosomal protein L32
FK178_12130	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
FK178_12135	ENOG4108R6K	riboflavin synthase, subunit alpha
FK178_12145	ENOG4107RAQ	aminopeptidase
FK178_12150	ENOG4105FQP	Beta-lactamase
FK178_12170	ENOG4108ZVT	methylmalonyl-coA epimerase
FK178_12175	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
FK178_12180	ENOG4105D60	lipoprotein releasing system transmembrane protein
FK178_12185	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
FK178_12195	ENOG4105D17	glycoside hydrolase, family 3 domain protein
FK178_12205	ENOG4105E2R	ROK family
FK178_12210	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
FK178_12215	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
FK178_12220	ENOG4105EHZ	conserved protein UCP016719
FK178_12225	ENOG4107SN7	NLP P60 protein
FK178_12230	ENOG4105DTQ	mandelate racemase muconate lactonizing
FK178_12235	ENOG4108IA2	Sodium pantothenate symporter
FK178_12240	ENOG4105F32	YngK protein
FK178_12255	ENOG4105C27	TonB-dependent Receptor Plug
FK178_12260	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
FK178_12265	ENOG4105E2D	ec 3.2.1.52
FK178_12290	ENOG4105C8F	Beta-lactamase domain protein
FK178_12305	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
FK178_12310	ENOG4105CN1	protease
FK178_12315	ENOG4107YB6	acetyltransferase, (GNAT) family
FK178_12325	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
FK178_12345	ENOG4105KRF	dihydroneopterin aldolase
FK178_12350	ENOG4105CX6	glutaminyL-tRNA synthetase
FK178_12380	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
FK178_12390	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
FK178_12395	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
FK178_12400	ENOG4108WVK	Could be a S-adenosyl-L-methionine-dependent methyltransferase (By similarity)
FK178_12415	ENOG4107QRG	dna polymerase iii
FK178_12420	ENOG4105BZA	Phosphoglycerate kinase
FK178_12425	ENOG41068JE	domain protein
FK178_12435	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
FK178_12440	ENOG4105DR5	peptidase
FK178_12455	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
FK178_12460	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
FK178_12475	ENOG4105DZS	Phenylacetate-CoA ligase
FK178_12480	ENOG4107QNG	Phosphoribosylglycinamide synthetase
FK178_12500	ENOG4105DVP	Adenine-specific
FK178_12510	ENOG4105DKP	glycosyl transferase, family 9
FK178_12550	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
FK178_12555	ENOG4105VHG	atp synthase
FK178_12560	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
FK178_12565	ENOG4107Z4P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
FK178_12570	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
FK178_12575	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
FK178_12590	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
FK178_12630	ENOG4105C31	Tryptophanyl-tRNA synthetase
FK178_12655	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
FK178_12660	ENOG4105C72	UPF0176 protein
FK178_12665	ENOG4105MA4	psp1 domain protein
FK178_12670	ENOG410647Z	gliding motility-associated lipoprotein GldH
FK178_12675	ENOG4108JQC	penicillin-binding protein 1A
FK178_12680	ENOG4107QP7	CoA-transferase subunit A
FK178_12690	ENOG4107RCH	Diaminopropionate ammonia-lyase
FK178_12710	ENOG4105EMU	Dehydrogenase
FK178_12720	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
FK178_12735	ENOG4107QVM	von Willebrand factor, type A
FK178_12740	ENOG4107QVM	von Willebrand factor, type A
FK178_12770	ENOG41077A9	carbonic anhydrase
FK178_12785	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
FK178_12795	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
FK178_12800	ENOG4109066	lysm domain bon superfamily protein
FK178_12805	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
FK178_12810	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
FK178_12815	ENOG4105DSJ	YicC domain protein
FK178_12825	ENOG4105DNZ	Alpha Beta Hydrolase
FK178_12835	ENOG4108PCN	EamA-like transporter family
FK178_12840	ENOG4105K89	arsenate reductase
FK178_12850	ENOG4105C28	cystathionine
FK178_12865	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
FK178_12875	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
FK178_12890	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
FK178_12895	ENOG4105DY9	regulatoR
FK178_12905	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
FK178_12915	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
FK178_12925	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
FK178_12935	ENOG4105F1J	Homogentisate 1,2-dioxygenase
FK178_12940	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
FK178_12960	ENOG4107QP8	phosphohexose isomerase
FK178_12965	ENOG4108KPZ	tonB-dependent Receptor
FK178_12990	ENOG4108Y6J	UPF0403 protein
FK178_13000	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
FK178_13005	ENOG4105UGU	tonB-dependent Receptor
FK178_13010	ENOG4107RPQ	ABC transporter
FK178_13030	ENOG4105CE1	Ferrous iron transport protein b
FK178_13040	ENOG4108KF3	Electron transport protein SCO1 SenC
FK178_13045	ENOG4105DZP	Membrane-associated zinc metalloprotease
FK178_13065	ENOG4105DAP	Nicotinate phosphoribosyltransferase
FK178_13070	ENOG4108RWI	nicotinamidase
FK178_13075	ENOG4105C9B	Cysteine desulfurase
FK178_13120	ENOG4105BZ1	(ABC) transporter
FK178_13145	ENOG4105ETE	Transcriptional regulator (LacI family
FK178_13195	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
FK178_13205	ENOG4107QNK	)-transporter
FK178_13210	ENOG4108Z6B	deaminase
FK178_13215	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
FK178_13235	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
FK178_13265	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
FK178_13275	ENOG4105C3M	thioredoxin reductase
FK178_13285	ENOG4105CN1	protease
FK178_13355	ENOG4108V0P	LemA family
FK178_13360	ENOG4105D0M	Protease HtpX homolog
FK178_13410	ENOG41082IR	Excinuclease ABC C subunit domain protein
FK178_13425	ENOG4105FCD	Major Facilitator
FK178_13445	ENOG4105CJ1	ABC, transporter
FK178_13450	ENOG4105CJ1	ABC, transporter
FK178_13455	ENOG4107QWP	ABC-2 type transporter
FK178_13460	ENOG4105CJ1	ABC, transporter
FK178_13480	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
FK178_13485	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
FK178_13490	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
FK178_13495	ENOG4105DTN	riboflavin biosynthesis protein ribF
FK178_13505	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
FK178_13525	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FK178_13530	ENOG4105CJW	magnesium transporter
FK178_13540	ENOG4108JQ1	Dehydrogenase
FK178_13545	ENOG41082IR	Excinuclease ABC C subunit domain protein
FK178_13565	ENOG4105CFH	Aspartokinase
FK178_13580	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
FK178_13595	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
FK178_13600	ENOG4107QRT	dEAD DEAH box helicase
FK178_13630	ENOG4108JA2	transcriptioN-repair coupling factor
FK178_13640	ENOG41080R2	UPF0102 protein
FK178_13650	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
FK178_13655	ENOG41082IR	Excinuclease ABC C subunit domain protein
FK178_13660	ENOG4105DGU	Histone deacetylase
FK178_13665	ENOG4108UUM	single-stranded DNA-binding protein
FK178_13695	ENOG4105W87	Cbs domain
FK178_13710	ENOG4105C9K	Endothelin-converting enzyme 1
FK178_13725	ENOG4105EXW	epimerase dehydratase
FK178_13730	ENOG4105VEQ	Cold shock protein
FK178_13740	ENOG4105CMQ	Chloride channel
FK178_13745	ENOG4105C9M	aspartyl-trna synthetase
FK178_13765	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
FK178_13790	ENOG4105C7S	Dehydrogenase
FK178_13805	ENOG4105F8V	Hydrolase, tatD family
FK178_13815	ENOG4105HDK	L-asparaginase
FK178_13855	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
FK178_13860	ENOG4105EI2	Pseudouridine synthase
FK178_13865	ENOG4105C5S	asparaginyl-tRNA synthetase
FK178_13880	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
FK178_13885	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
FK178_13905	ENOG4108VVK	transcriptional Regulator, AsnC
FK178_13920	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
FK178_13935	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
FK178_13940	ENOG4105CD3	dihydroorotase
FK178_13955	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
FK178_13975	ENOG4105C27	TonB-dependent Receptor Plug
FK178_13980	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
FK178_13985	ENOG4105BZU	Histidine kinase
FK178_13990	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
FK178_13995	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
FK178_14005	ENOG41080UX	Methyltransferase
FK178_14020	ENOG4105CAY	ferredoxin--nadp reductase
FK178_14040	ENOG4105C1G	acyl-Coa dehydrogenase
FK178_14050	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
FK178_14055	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
FK178_14060	ENOG4105K5M	30s ribosomal protein S16
FK178_14070	ENOG4105C0B	DNA polymerase III (alpha subunit)
FK178_14075	ENOG4105K63	Thioredoxin
FK178_14110	ENOG4105DEN	Luciferase family
FK178_14125	ENOG4105C8P	)-transporter
FK178_14130	ENOG4108IGT	Dipeptidase
FK178_14150	ENOG4108UUM	single-stranded DNA-binding protein
FK178_14210	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
FK178_14220	ENOG4105CSA	Coproporphyrinogen iii oxidase
FK178_14235	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
FK178_14240	ENOG4105CE9	30S ribosomal protein S2
FK178_14245	ENOG4108UJD	30S ribosomal protein S9
FK178_14250	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
FK178_14265	ENOG4105C27	TonB-dependent Receptor Plug
FK178_14275	ENOG4105C2M	dna polymerase I
FK178_14285	ENOG4105K63	Thioredoxin
FK178_14290	ENOG4108ZJ4	polysaccharide deacetylase
FK178_14305	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
FK178_14310	ENOG4105E6M	Sulphatase-modifying factor protein
FK178_14320	ENOG4105KG3	cytidine deaminase
FK178_14350	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
FK178_14360	ENOG4105DHJ	ABC, transporter
FK178_14375	ENOG4105CKK	Glycosyl transferase, family 2
FK178_14390	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
FK178_14410	ENOG4105DGW	oligopeptidase A
FK178_14415	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
FK178_14425	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
FK178_14430	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
FK178_14440	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
FK178_14460	ENOG4105DFU	Cell wall formation (By similarity)
FK178_14465	ENOG4105W5Q	DNA repair protein (RadC
FK178_14495	ENOG4105D1H	recombination factor protein RarA
FK178_14505	ENOG4105C2N	RNA methyltransferase TrmH family group 3
FK178_14515	ENOG4105C27	TonB-dependent Receptor Plug
FK178_14520	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
FK178_14525	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
FK178_14530	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
FK178_14535	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
FK178_14540	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
FK178_14545	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
FK178_14550	ENOG41082S5	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
FK178_14555	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
FK178_14560	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
FK178_14565	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
FK178_14570	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
FK178_14575	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
FK178_14580	ENOG4105WNB	50s ribosomal protein l29
FK178_14585	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
FK178_14590	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
FK178_14595	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
FK178_14600	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
FK178_14605	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
FK178_14610	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
FK178_14615	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
FK178_14620	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
FK178_14625	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
FK178_14630	ENOG41084HK	50S ribosomal protein L30
FK178_14635	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
FK178_14640	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
FK178_14645	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
FK178_14650	ENOG410864M	50S ribosomal protein L36
FK178_14655	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
FK178_14660	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
FK178_14665	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
FK178_14670	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
FK178_14675	ENOG4108ZT0	50S ribosomal protein l17
FK178_14680	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
FK178_14700	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
FK178_14710	ENOG4108K2F	hydrolase Family 5
FK178_14745	ENOG4105C75	arginyL-tRNA synthetase
FK178_14760	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
FK178_14780	ENOG4105FE9	pseudouridine synthase
FK178_14800	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
FK178_14805	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
FK178_14810	ENOG4105C27	TonB-dependent Receptor Plug
FK178_14825	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
FK178_14835	ENOG4105CAQ	asparagine synthetase
FK178_14840	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
FK178_14850	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
FK178_14855	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
FK178_14865	ENOG4107QZC	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
FK178_14870	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
FK178_14875	ENOG4105C8N	cysteinyl-tRNA synthetase
FK178_14880	ENOG4105EUJ	GTP cyclohydrolase i
FK178_14905	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
FK178_14920	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
FK178_14925	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
FK178_14935	ENOG4107YM1	mraZ protein
FK178_14940	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
FK178_14955	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
FK178_14960	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
FK178_14965	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
FK178_14975	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
FK178_14980	ENOG4105DFU	Cell wall formation (By similarity)
FK178_14990	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
FK178_14995	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
FK178_15000	ENOG4105KTH	gatB Yqey
FK178_15010	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
FK178_15050	ENOG4105BZU	Histidine kinase
FK178_15120	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
FK178_15135	ENOG4105BZU	Histidine kinase
FK178_15150	ENOG4105CKW	Inner membrane protein yedI
FK178_15180	ENOG4108HRK	Histidine kinase
FK178_15195	ENOG4105CI2	imidazolone-5-propionate hydrolase
FK178_15200	ENOG4105BZU	Histidine kinase
FK178_15205	ENOG4105DY9	regulatoR
FK178_15210	ENOG4108HRK	Histidine kinase
FK178_15220	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
FK178_15235	ENOG4105DZR	Type I site-specific deoxyribonuclease
FK178_15240	ENOG4105EKX	Restriction modification system DNA (Specificity
FK178_15285	ENOG4105CVR	type I restriction-modification system
FK178_15315	ENOG4105C27	TonB-dependent Receptor Plug
FK178_15330	ENOG4105C84	Histidine ammonia-lyase
FK178_15335	ENOG4105CGP	Urocanate hydratase
FK178_15340	ENOG4105C6Z	Gluconate
FK178_15345	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
FK178_15380	ENOG4105ENE	Histidine kinase