locus-tag	class	description
ANTHELSMS3_00001	COG1183	phosphatidylcholine synthase activity
ANTHELSMS3_00003	COG3386	PFAM SMP-30 Gluconolaconase
ANTHELSMS3_00004	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_00007	COG0559	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_00009	COG0411	ABC transporter
ANTHELSMS3_00015	COG0493	'glutamate synthase
ANTHELSMS3_00018	COG1309	transcriptional regulator
ANTHELSMS3_00023	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
ANTHELSMS3_00025	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANTHELSMS3_00026	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANTHELSMS3_00032	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
ANTHELSMS3_00035	COG3453	Protein conserved in bacteria
ANTHELSMS3_00035	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ANTHELSMS3_00038	COG1215	transferase activity, transferring glycosyl groups
ANTHELSMS3_00039	COG3769	mannosylglycerate metabolic process
ANTHELSMS3_00040	COG1072	(Pantothenic acid kinase))
ANTHELSMS3_00041	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ANTHELSMS3_00044	COG3208	Thioesterase involved in non-ribosomal peptide biosynthesis
ANTHELSMS3_00045	COG4325	translation initiation factor activity
ANTHELSMS3_00046	COG0628	permease
ANTHELSMS3_00052	COG3920	Histidine kinase
ANTHELSMS3_00057	COG3237	CsbD-like
ANTHELSMS3_00058	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ANTHELSMS3_00062	COG0784	Response regulator, receiver
ANTHELSMS3_00065	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ANTHELSMS3_00066	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ANTHELSMS3_00066	COG1321	iron dependent repressor
ANTHELSMS3_00067	COG1121	(ABC) transporter
ANTHELSMS3_00068	COG0803	Belongs to the bacterial solute-binding protein 9 family
ANTHELSMS3_00069	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
ANTHELSMS3_00072	COG0736	holo-[acyl-carrier-protein] synthase activity
ANTHELSMS3_00075	COG0681	Belongs to the peptidase S26 family
ANTHELSMS3_00077	COG0571	ribonuclease III activity
ANTHELSMS3_00079	COG0697	spore germination
ANTHELSMS3_00080	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
ANTHELSMS3_00082	COG1381	Involved in DNA repair and RecF pathway recombination
ANTHELSMS3_00084	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ANTHELSMS3_00086	COG0314	molybdopterin synthase activity
ANTHELSMS3_00087	COG2186	Transcriptional regulator
ANTHELSMS3_00088	COG0004	ammonium transporteR
ANTHELSMS3_00089	COG0347	Belongs to the P(II) protein family
ANTHELSMS3_00090	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ANTHELSMS3_00093	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
ANTHELSMS3_00094	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANTHELSMS3_00098	COG0495	leucyl-tRNA aminoacylation
ANTHELSMS3_00099	COG0438	transferase activity, transferring glycosyl groups
ANTHELSMS3_00102	COG0457	Tetratricopeptide repeat
ANTHELSMS3_00103	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ANTHELSMS3_00104	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ANTHELSMS3_00105	COG0196	riboflavin kinase activity
ANTHELSMS3_00106	COG2983	Belongs to the UPF0260 family
ANTHELSMS3_00111	COG3932	Exopolysaccharide synthesis, ExoD
ANTHELSMS3_00112	COG1674	ftsk spoiiie
ANTHELSMS3_00113	COG0436	Aminotransferase
ANTHELSMS3_00115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ANTHELSMS3_00116	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_00129	COG0435	Glutathione S-transferase
ANTHELSMS3_00132	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
ANTHELSMS3_00133	COG0242	peptide deformylase activity
ANTHELSMS3_00134	COG0242	peptide deformylase activity
ANTHELSMS3_00135	COG0242	peptide deformylase activity
ANTHELSMS3_00136	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ANTHELSMS3_00137	COG2860	membrane
ANTHELSMS3_00138	COG0328	RNA-DNA hybrid ribonuclease activity
ANTHELSMS3_00140	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
ANTHELSMS3_00142	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
ANTHELSMS3_00143	COG1758	RNA polymerase activity
ANTHELSMS3_00144	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ANTHELSMS3_00149	COG2154	pterin-4-alpha-carbinolamine dehydratase
ANTHELSMS3_00150	COG0678	peroxiredoxin activity
ANTHELSMS3_00152	COG0742	ribosomal rna small subunit methyltransferase
ANTHELSMS3_00156	COG0024	Methionine aminopeptidase
ANTHELSMS3_00165	COG1194	a g-specific adenine glycosylase
ANTHELSMS3_00166	COG3239	Fatty acid desaturase
ANTHELSMS3_00168	COG1489	DNA binding
ANTHELSMS3_00169	COG1058	Belongs to the CinA family
ANTHELSMS3_00169	COG1546	Belongs to the CinA family
ANTHELSMS3_00173	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_00175	COG0693	protein deglycase activity
ANTHELSMS3_00176	COG0446	pyridine nucleotide-disulphide oxidoreductase
ANTHELSMS3_00176	COG1902	pentaerythritol trinitrate reductase activity
ANTHELSMS3_00180	COG1012	belongs to the aldehyde dehydrogenase family
ANTHELSMS3_00181	COG0799	negative regulation of ribosome biogenesis
ANTHELSMS3_00182	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
ANTHELSMS3_00183	COG1968	undecaprenyl-diphosphatase activity
ANTHELSMS3_00188	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ANTHELSMS3_00191	COG1459	type II secretion system
ANTHELSMS3_00192	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
ANTHELSMS3_00199	COG0697	spore germination
ANTHELSMS3_00200	COG1131	(ABC) transporter
ANTHELSMS3_00201	COG0842	Transport permease protein
ANTHELSMS3_00209	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
ANTHELSMS3_00217	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
ANTHELSMS3_00220	COG2226	methyltransferase
ANTHELSMS3_00221	COG0039	L-malate dehydrogenase activity
ANTHELSMS3_00228	COG0625	glutathione transferase activity
ANTHELSMS3_00229	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
ANTHELSMS3_00230	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
ANTHELSMS3_00231	COG0124	histidyl-tRNA synthetase
ANTHELSMS3_00234	COG0587	DNA-directed DNA polymerase activity
ANTHELSMS3_00239	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ANTHELSMS3_00248	COG0667	Aldo Keto reductase
ANTHELSMS3_00251	COG1201	RNA secondary structure unwinding
ANTHELSMS3_00260	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
ANTHELSMS3_00261	COG1605	Chorismate mutase
ANTHELSMS3_00261	COG0287	Prephenate dehydrogenase
ANTHELSMS3_00262	COG2759	Belongs to the formate--tetrahydrofolate ligase family
ANTHELSMS3_00264	COG4106	trans-aconitate 2-methyltransferase activity
ANTHELSMS3_00265	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ANTHELSMS3_00266	COG0037	tRNA processing
ANTHELSMS3_00268	COG2885	chlorophyll binding
ANTHELSMS3_00273	COG0824	Thioesterase
ANTHELSMS3_00274	COG1196	nuclear chromosome segregation
ANTHELSMS3_00274	COG3264	Mechanosensitive ion channel
ANTHELSMS3_00278	COG4948	Mandelate Racemase Muconate Lactonizing
ANTHELSMS3_00280	COG2301	Belongs to the HpcH HpaI aldolase family
ANTHELSMS3_00281	COG1522	sequence-specific DNA binding
ANTHELSMS3_00284	COG0825	malonyl-CoA metabolic process
ANTHELSMS3_00288	COG1802	Transcriptional regulator
ANTHELSMS3_00296	COG1278	Cold shock
ANTHELSMS3_00297	COG1607	acyl-coa hydrolase
ANTHELSMS3_00300	COG4154	Belongs to the RbsD FucU family
ANTHELSMS3_00303	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
ANTHELSMS3_00305	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
ANTHELSMS3_00307	COG0804	urea catabolic process
ANTHELSMS3_00310	COG0832	Belongs to the urease beta subunit family
ANTHELSMS3_00312	COG0831	urea catabolic process
ANTHELSMS3_00313	COG0829	nickel cation binding
ANTHELSMS3_00316	COG0454	-acetyltransferase
ANTHELSMS3_00317	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_00320	COG0840	transmembrane signaling receptor activity
ANTHELSMS3_00322	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ANTHELSMS3_00325	COG0667	Aldo Keto reductase
ANTHELSMS3_00327	COG0765	amino acid transport
ANTHELSMS3_00335	COG1609	Transcriptional regulator
ANTHELSMS3_00336	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANTHELSMS3_00337	COG3962	Belongs to the TPP enzyme family
ANTHELSMS3_00341	COG3718	enzyme involved in inositol metabolism
ANTHELSMS3_00342	COG0277	FAD linked oxidase domain protein
ANTHELSMS3_00345	COG2816	NAD+ diphosphatase activity
ANTHELSMS3_00346	COG0737	Belongs to the 5'-nucleotidase family
ANTHELSMS3_00347	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ANTHELSMS3_00353	COG2321	neutral zinc metallopeptidase
ANTHELSMS3_00357	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
ANTHELSMS3_00359	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
ANTHELSMS3_00365	COG0318	PFAM AMP-dependent synthetase and ligase
ANTHELSMS3_00368	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
ANTHELSMS3_00369	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
ANTHELSMS3_00370	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
ANTHELSMS3_00371	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
ANTHELSMS3_00373	COG0281	malic enzyme
ANTHELSMS3_00373	COG0280	phosphate acetyltransferase
ANTHELSMS3_00375	COG0024	Methionine aminopeptidase
ANTHELSMS3_00380	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
ANTHELSMS3_00381	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
ANTHELSMS3_00386	COG3739	integral membrane protein
ANTHELSMS3_00393	COG0667	Aldo Keto reductase
ANTHELSMS3_00396	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ANTHELSMS3_00397	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
ANTHELSMS3_00398	COG2267	carboxylic ester hydrolase activity
ANTHELSMS3_00400	COG1047	Peptidyl-prolyl cis-trans
ANTHELSMS3_00402	COG0596	Alpha beta hydrolase
ANTHELSMS3_00404	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ANTHELSMS3_00406	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ANTHELSMS3_00408	COG0640	Transcriptional regulator
ANTHELSMS3_00409	COG0154	amidase activity
ANTHELSMS3_00410	COG0318	PFAM AMP-dependent synthetase and ligase
ANTHELSMS3_00413	COG2135	peptidase activity
ANTHELSMS3_00415	COG1803	Methylglyoxal synthase
ANTHELSMS3_00416	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
ANTHELSMS3_00418	COG1132	(ABC) transporter
ANTHELSMS3_00419	COG0737	Belongs to the 5'-nucleotidase family
ANTHELSMS3_00422	COG0167	dihydroorotate dehydrogenase activity
ANTHELSMS3_00423	COG0135	phosphoribosylanthranilate isomerase activity
ANTHELSMS3_00425	COG0776	regulation of translation
ANTHELSMS3_00429	COG0539	negative regulation of cytoplasmic translation
ANTHELSMS3_00433	COG3454	Phosphonate metabolism
ANTHELSMS3_00436	COG4778	phosphonate C-P lyase system protein PhnL
ANTHELSMS3_00437	COG0598	Magnesium transport protein CorA
ANTHELSMS3_00438	COG4107	phosphonate C-P lyase system protein PhnK
ANTHELSMS3_00439	COG3627	carbon phosphorus lyase activity
ANTHELSMS3_00441	COG3626	phosphonate metabolism
ANTHELSMS3_00443	COG3624	Phosphonate C-P lyase system protein PhnG
ANTHELSMS3_00444	COG2188	Transcriptional regulator
ANTHELSMS3_00445	COG3454	Phosphonate metabolism
ANTHELSMS3_00447	COG3639	organic phosphonate transmembrane transporter activity
ANTHELSMS3_00448	COG3639	organic phosphonate transmembrane transporter activity
ANTHELSMS3_00449	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
ANTHELSMS3_00452	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
ANTHELSMS3_00455	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_00456	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_00458	COG2890	protein-(glutamine-N5) methyltransferase activity
ANTHELSMS3_00460	COG0142	geranyltranstransferase activity
ANTHELSMS3_00461	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
ANTHELSMS3_00465	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ANTHELSMS3_00467	COG0303	'Molybdopterin
ANTHELSMS3_00468	COG1763	Mo-molybdopterin cofactor biosynthetic process
ANTHELSMS3_00469	COG0746	molybdenum cofactor guanylyltransferase activity
ANTHELSMS3_00470	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
ANTHELSMS3_00476	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_00477	COG0009	L-threonylcarbamoyladenylate synthase
ANTHELSMS3_00478	COG1678	Uncharacterized ACR, COG1678
ANTHELSMS3_00482	COG0521	Mo-molybdopterin cofactor biosynthetic process
ANTHELSMS3_00483	COG1280	lysine exporter protein (LysE YggA)
ANTHELSMS3_00484	COG1573	uracil-dna glycosylase
ANTHELSMS3_00485	COG0540	Belongs to the ATCase OTCase family
ANTHELSMS3_00490	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
ANTHELSMS3_00491	COG2267	carboxylic ester hydrolase activity
ANTHELSMS3_00495	COG2095	MarC family integral membrane protein
ANTHELSMS3_00497	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ANTHELSMS3_00498	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
ANTHELSMS3_00499	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
ANTHELSMS3_00500	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
ANTHELSMS3_00501	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ANTHELSMS3_00503	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ANTHELSMS3_00508	COG1309	transcriptional regulator
ANTHELSMS3_00512	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ANTHELSMS3_00513	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
ANTHELSMS3_00514	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
ANTHELSMS3_00520	COG4172	Belongs to the ABC transporter superfamily
ANTHELSMS3_00521	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_00524	COG0840	transmembrane signaling receptor activity
ANTHELSMS3_00525	COG3191	aminopeptidase activity
ANTHELSMS3_00527	COG1573	uracil-dna glycosylase
ANTHELSMS3_00532	COG4191	Histidine kinase
ANTHELSMS3_00532	COG0784	Response regulator, receiver
ANTHELSMS3_00536	COG0483	inositol monophosphate 1-phosphatase activity
ANTHELSMS3_00539	COG1840	ABC-type Fe3 transport system, periplasmic component
ANTHELSMS3_00542	COG1349	DNA-binding transcription factor activity
ANTHELSMS3_00544	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ANTHELSMS3_00545	COG3639	organic phosphonate transmembrane transporter activity
ANTHELSMS3_00547	COG1011	Hydrolase
ANTHELSMS3_00553	COG0438	transferase activity, transferring glycosyl groups
ANTHELSMS3_00554	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANTHELSMS3_00555	COG1682	transport, permease protein
ANTHELSMS3_00556	COG1134	teichoic acid transport
ANTHELSMS3_00559	COG2072	flavoprotein involved in K transport
ANTHELSMS3_00560	COG4638	Rieske (2fe-2S)
ANTHELSMS3_00567	COG3842	ATPase activity
ANTHELSMS3_00568	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANTHELSMS3_00569	COG1177	transmembrane transport
ANTHELSMS3_00571	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ANTHELSMS3_00571	COG1648	precorrin-2 dehydrogenase activity
ANTHELSMS3_00572	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ANTHELSMS3_00573	COG0243	molybdopterin cofactor binding
ANTHELSMS3_00574	COG2146	nitrite reductase [NAD(P)H] activity
ANTHELSMS3_00575	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ANTHELSMS3_00577	COG1116	anion transmembrane transporter activity
ANTHELSMS3_00577	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANTHELSMS3_00578	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANTHELSMS3_00579	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANTHELSMS3_00580	COG1116	anion transmembrane transporter activity
ANTHELSMS3_00580	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANTHELSMS3_00581	COG3707	response regulator
ANTHELSMS3_00588	COG1175	transmembrane transport
ANTHELSMS3_00592	COG0673	inositol 2-dehydrogenase activity
ANTHELSMS3_00593	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ANTHELSMS3_00595	COG4989	oxidoreductase activity
ANTHELSMS3_00599	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ANTHELSMS3_00602	COG1858	cytochrome C peroxidase
ANTHELSMS3_00603	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANTHELSMS3_00608	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ANTHELSMS3_00611	COG1178	ABC-type Fe3 transport system permease component
ANTHELSMS3_00612	COG1840	ABC-type Fe3 transport system, periplasmic component
ANTHELSMS3_00613	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANTHELSMS3_00613	COG1024	Enoyl-CoA hydratase
ANTHELSMS3_00615	COG1522	sequence-specific DNA binding
ANTHELSMS3_00616	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ANTHELSMS3_00617	COG0179	Fumarylacetoacetate (FAA) hydrolase
ANTHELSMS3_00619	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_00621	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_00622	COG2721	sulfolactate sulfo-lyase activity
ANTHELSMS3_00623	COG1802	Transcriptional regulator
ANTHELSMS3_00626	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ANTHELSMS3_00627	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ANTHELSMS3_00628	COG2808	Putative FMN-binding domain
ANTHELSMS3_00629	COG0203	ribosomal protein L17
ANTHELSMS3_00630	COG0202	RNA polymerase activity
ANTHELSMS3_00631	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
ANTHELSMS3_00632	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
ANTHELSMS3_00634	COG0201	protein transport
ANTHELSMS3_00635	COG0200	Binds to the 23S rRNA
ANTHELSMS3_00638	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ANTHELSMS3_00639	COG0513	Belongs to the DEAD box helicase family
ANTHELSMS3_00640	COG1841	ribosomal large subunit assembly
ANTHELSMS3_00641	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
ANTHELSMS3_00642	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
ANTHELSMS3_00643	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
ANTHELSMS3_00644	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
ANTHELSMS3_00645	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
ANTHELSMS3_00646	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
ANTHELSMS3_00647	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
ANTHELSMS3_00649	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
ANTHELSMS3_00650	COG0255	Belongs to the universal ribosomal protein uL29 family
ANTHELSMS3_00655	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
ANTHELSMS3_00656	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
ANTHELSMS3_00657	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
ANTHELSMS3_00658	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
ANTHELSMS3_00659	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
ANTHELSMS3_00661	COG0089	rRNA binding
ANTHELSMS3_00662	COG0088	Forms part of the polypeptide exit tunnel
ANTHELSMS3_00663	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
ANTHELSMS3_00664	COG0051	transcription antitermination factor activity, RNA binding
ANTHELSMS3_00665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ANTHELSMS3_00666	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ANTHELSMS3_00667	COG0049	tRNA binding
ANTHELSMS3_00668	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
ANTHELSMS3_00670	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
ANTHELSMS3_00671	COG0085	RNA polymerase activity
ANTHELSMS3_00672	COG0222	ribosome binding
ANTHELSMS3_00673	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
ANTHELSMS3_00675	COG0784	Response regulator, receiver
ANTHELSMS3_00675	COG2205	protein histidine kinase activity
ANTHELSMS3_00677	COG0081	regulation of translation
ANTHELSMS3_00678	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
ANTHELSMS3_00679	COG0250	Participates in transcription elongation, termination and antitermination
ANTHELSMS3_00687	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
ANTHELSMS3_00689	COG2096	Adenosyltransferase
ANTHELSMS3_00691	COG0300	oxidoreductase activity
ANTHELSMS3_00693	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ANTHELSMS3_00697	COG0501	Belongs to the peptidase M48B family
ANTHELSMS3_00701	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANTHELSMS3_00703	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANTHELSMS3_00707	COG2205	protein histidine kinase activity
ANTHELSMS3_00708	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_00709	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
ANTHELSMS3_00711	COG3246	L-lysine catabolic process to acetate
ANTHELSMS3_00712	COG3485	protocatechuate 3,4-dioxygenase
ANTHELSMS3_00713	COG3485	protocatechuate 3,4-dioxygenase
ANTHELSMS3_00714	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
ANTHELSMS3_00716	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_00719	COG2814	Major facilitator Superfamily
ANTHELSMS3_00722	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ANTHELSMS3_00728	COG1435	thymidine kinase activity
ANTHELSMS3_00735	COG0842	Transport permease protein
ANTHELSMS3_00738	COG0473	3-isopropylmalate dehydrogenase activity
ANTHELSMS3_00741	COG0683	leucine binding
ANTHELSMS3_00751	COG1131	(ABC) transporter
ANTHELSMS3_00752	COG1116	anion transmembrane transporter activity
ANTHELSMS3_00757	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_00758	COG4948	Mandelate Racemase Muconate Lactonizing
ANTHELSMS3_00763	COG0058	SHG alpha-glucan phosphorylase activity
ANTHELSMS3_00764	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
ANTHELSMS3_00765	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
ANTHELSMS3_00766	COG0297	glycogen (starch) synthase activity
ANTHELSMS3_00768	COG1640	4-alpha-glucanotransferase
ANTHELSMS3_00769	COG0033	Phosphoglucomutase
ANTHELSMS3_00770	COG0779	Required for maturation of 30S ribosomal subunits
ANTHELSMS3_00773	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
ANTHELSMS3_00776	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
ANTHELSMS3_00777	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
ANTHELSMS3_00778	COG0653	protein targeting
ANTHELSMS3_00781	COG2003	Belongs to the UPF0758 family
ANTHELSMS3_00782	COG0484	heat shock protein binding
ANTHELSMS3_00783	COG0443	Heat shock 70 kDa protein
ANTHELSMS3_00784	COG3145	DNA-N1-methyladenine dioxygenase activity
ANTHELSMS3_00791	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ANTHELSMS3_00796	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ANTHELSMS3_00798	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
ANTHELSMS3_00799	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ANTHELSMS3_00800	COG1137	ATPase activity
ANTHELSMS3_00805	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
ANTHELSMS3_00808	COG2885	chlorophyll binding
ANTHELSMS3_00810	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
ANTHELSMS3_00811	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
ANTHELSMS3_00812	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANTHELSMS3_00814	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ANTHELSMS3_00814	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
ANTHELSMS3_00815	COG1272	protein, Hemolysin III
ANTHELSMS3_00816	COG1741	Belongs to the pirin family
ANTHELSMS3_00818	COG1131	(ABC) transporter
ANTHELSMS3_00822	COG0698	ribose 5-phosphate isomerase
ANTHELSMS3_00824	COG0714	Associated with various cellular activities
ANTHELSMS3_00831	COG0277	FAD linked oxidase domain protein
ANTHELSMS3_00832	COG0277	FAD linked oxidase domain protein
ANTHELSMS3_00834	COG0247	lactate metabolic process
ANTHELSMS3_00837	COG0071	Belongs to the small heat shock protein (HSP20) family
ANTHELSMS3_00840	COG2304	oxidoreductase activity
ANTHELSMS3_00843	COG1012	belongs to the aldehyde dehydrogenase family
ANTHELSMS3_00852	COG0437	4 iron, 4 sulfur cluster binding
ANTHELSMS3_00853	COG0243	molybdopterin cofactor binding
ANTHELSMS3_00854	COG0280	phosphate acetyltransferase
ANTHELSMS3_00854	COG0857	belongs to the CobB CobQ family
ANTHELSMS3_00855	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ANTHELSMS3_00856	COG0028	Belongs to the TPP enzyme family
ANTHELSMS3_00866	COG4221	oxidoreductase activity
ANTHELSMS3_00870	COG0438	transferase activity, transferring glycosyl groups
ANTHELSMS3_00870	COG0297	glycogen (starch) synthase activity
ANTHELSMS3_00872	COG0673	inositol 2-dehydrogenase activity
ANTHELSMS3_00873	COG0489	protein tyrosine kinase activity
ANTHELSMS3_00880	COG0438	transferase activity, transferring glycosyl groups
ANTHELSMS3_00883	COG0662	Cupin 2, conserved barrel domain protein
ANTHELSMS3_00884	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ANTHELSMS3_00885	COG2824	Alkylphosphonate utilization operon protein PhnA
ANTHELSMS3_00886	COG0405	Gamma-glutamyltransferase
ANTHELSMS3_00891	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
ANTHELSMS3_00892	COG0517	IMP dehydrogenase activity
ANTHELSMS3_00892	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
ANTHELSMS3_00893	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
ANTHELSMS3_00894	COG2877	3-deoxy-8-phosphooctulonate synthase activity
ANTHELSMS3_00895	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
ANTHELSMS3_00899	COG0348	domain, Protein
ANTHELSMS3_00899	COG3901	Regulator of nitric oxide reductase transcription
ANTHELSMS3_00911	COG0640	Transcriptional regulator
ANTHELSMS3_00912	COG0701	Predicted permease
ANTHELSMS3_00914	COG1982	Orn Lys Arg decarboxylase major
ANTHELSMS3_00917	COG4999	Histidine kinase
ANTHELSMS3_00917	COG2205	protein histidine kinase activity
ANTHELSMS3_00917	COG3437	response regulator, receiver
ANTHELSMS3_00917	COG3850	Histidine kinase
ANTHELSMS3_00919	COG3051	citrate lyase alpha subunit
ANTHELSMS3_00922	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ANTHELSMS3_00927	COG2828	Protein conserved in bacteria
ANTHELSMS3_00929	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANTHELSMS3_00930	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_00932	COG0473	3-isopropylmalate dehydrogenase activity
ANTHELSMS3_00934	COG1053	succinate dehydrogenase
ANTHELSMS3_00939	COG1802	Transcriptional regulator
ANTHELSMS3_00943	COG3485	protocatechuate 3,4-dioxygenase
ANTHELSMS3_00947	COG0778	Nitroreductase
ANTHELSMS3_00948	COG0179	Fumarylacetoacetate (FAA) hydrolase
ANTHELSMS3_00951	COG0318	PFAM AMP-dependent synthetase and ligase
ANTHELSMS3_00955	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ANTHELSMS3_00956	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
ANTHELSMS3_00964	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ANTHELSMS3_00966	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
ANTHELSMS3_00969	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_00970	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
ANTHELSMS3_00971	COG1999	signal sequence binding
ANTHELSMS3_00975	COG3178	'Phosphotransferase
ANTHELSMS3_00976	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
ANTHELSMS3_00978	COG1074	ATP-dependent DNA helicase activity
ANTHELSMS3_00980	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
ANTHELSMS3_00981	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
ANTHELSMS3_00982	COG0754	glutathionylspermidine amidase activity
ANTHELSMS3_00984	COG0747	negative chemotaxis
ANTHELSMS3_00985	COG4172	Belongs to the ABC transporter superfamily
ANTHELSMS3_00986	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_00987	COG0601	transmembrane transport
ANTHELSMS3_00989	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
ANTHELSMS3_00991	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ANTHELSMS3_00994	COG2226	methyltransferase
ANTHELSMS3_00999	COG3034	peptidoglycan biosynthetic process
ANTHELSMS3_01001	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
ANTHELSMS3_01002	COG1132	(ABC) transporter
ANTHELSMS3_01003	COG1132	(ABC) transporter
ANTHELSMS3_01004	COG1132	(ABC) transporter
ANTHELSMS3_01005	COG0617	tRNA 3'-terminal CCA addition
ANTHELSMS3_01006	COG0494	nUDIX hydrolase
ANTHELSMS3_01007	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
ANTHELSMS3_01008	COG0494	nUDIX hydrolase
ANTHELSMS3_01012	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ANTHELSMS3_01014	COG0137	argininosuccinate synthase activity
ANTHELSMS3_01017	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ANTHELSMS3_01019	COG0280	phosphate acetyltransferase
ANTHELSMS3_01019	COG0281	malic enzyme
ANTHELSMS3_01020	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
ANTHELSMS3_01021	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
ANTHELSMS3_01023	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
ANTHELSMS3_01024	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
ANTHELSMS3_01025	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ANTHELSMS3_01026	COG1475	DNA binding
ANTHELSMS3_01027	COG1192	Involved in chromosome partitioning
ANTHELSMS3_01028	COG0357	Ribosomal RNA small subunit methyltransferase G
ANTHELSMS3_01029	COG0445	tRNA wobble uridine modification
ANTHELSMS3_01030	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
ANTHELSMS3_01031	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
ANTHELSMS3_01032	COG0424	maF-like protein
ANTHELSMS3_01033	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ANTHELSMS3_01034	COG0237	dephospho-CoA kinase activity
ANTHELSMS3_01036	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
ANTHELSMS3_01037	COG3030	protein affecting phage T7 exclusion by the F plasmid
ANTHELSMS3_01046	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ANTHELSMS3_01047	COG1360	Flagellar Motor Protein
ANTHELSMS3_01051	COG1706	bacterial-type flagellum-dependent cell motility
ANTHELSMS3_01052	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
ANTHELSMS3_01054	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ANTHELSMS3_01056	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
ANTHELSMS3_01059	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
ANTHELSMS3_01061	COG4786	Flagellar basal body rod
ANTHELSMS3_01062	COG4786	Flagellar basal body rod
ANTHELSMS3_01063	COG1987	bacterial-type flagellum assembly
ANTHELSMS3_01064	COG1677	Flagellar hook-basal body complex protein FliE
ANTHELSMS3_01065	COG1558	bacterial-type flagellum-dependent cell motility
ANTHELSMS3_01066	COG1815	bacterial-type flagellum-dependent cell motility
ANTHELSMS3_01067	COG1157	protein secretion by the type III secretion system
ANTHELSMS3_01069	COG5443	negative regulation of bacterial-type flagellum assembly
ANTHELSMS3_01075	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
ANTHELSMS3_01078	COG2226	methyltransferase
ANTHELSMS3_01079	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
ANTHELSMS3_01081	COG0268	Binds directly to 16S ribosomal RNA
ANTHELSMS3_01082	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ANTHELSMS3_01083	COG0592	DNA-directed DNA polymerase activity
ANTHELSMS3_01084	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
ANTHELSMS3_01086	COG0187	DNA topoisomerase II activity
ANTHELSMS3_01087	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_01088	COG3708	Transcriptional regulator
ANTHELSMS3_01088	COG2207	Transcriptional regulator
ANTHELSMS3_01090	COG1320	monovalent cation:proton antiporter activity
ANTHELSMS3_01091	COG2212	antiporter activity
ANTHELSMS3_01092	COG1863	multisubunit Na H antiporter MnhE subunit
ANTHELSMS3_01093	COG0651	ATP synthesis coupled electron transport
ANTHELSMS3_01094	COG1006	Multisubunit Na H antiporter MnhC subunit
ANTHELSMS3_01095	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
ANTHELSMS3_01095	COG2111	Na H antiporter
ANTHELSMS3_01096	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANTHELSMS3_01098	COG0725	ABC transporter, periplasmic molybdate-binding protein
ANTHELSMS3_01099	COG4149	molybdate abc transporter
ANTHELSMS3_01100	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
ANTHELSMS3_01102	COG3046	protein related to deoxyribodipyrimidine photolyase
ANTHELSMS3_01104	COG2197	response regulator
ANTHELSMS3_01110	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
ANTHELSMS3_01112	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ANTHELSMS3_01114	COG1959	2 iron, 2 sulfur cluster binding
ANTHELSMS3_01115	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ANTHELSMS3_01116	COG0509	glycine decarboxylation via glycine cleavage system
ANTHELSMS3_01117	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ANTHELSMS3_01117	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ANTHELSMS3_01119	COG0784	Response regulator, receiver
ANTHELSMS3_01119	COG4191	Histidine kinase
ANTHELSMS3_01120	COG0483	inositol monophosphate 1-phosphatase activity
ANTHELSMS3_01122	COG4181	ATPase activity
ANTHELSMS3_01125	COG0446	pyridine nucleotide-disulphide oxidoreductase
ANTHELSMS3_01125	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ANTHELSMS3_01126	COG1376	ErfK ybiS ycfS ynhG family protein
ANTHELSMS3_01130	COG1766	The M ring may be actively involved in energy transduction
ANTHELSMS3_01132	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
ANTHELSMS3_01133	COG1338	Plays a role in the flagellum-specific transport system
ANTHELSMS3_01136	COG0443	Heat shock 70 kDa protein
ANTHELSMS3_01137	COG1335	isochorismatase
ANTHELSMS3_01138	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
ANTHELSMS3_01140	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ANTHELSMS3_01141	COG0287	Prephenate dehydrogenase
ANTHELSMS3_01143	COG2268	Band 7 protein
ANTHELSMS3_01144	COG1585	Membrane protein implicated in regulation of membrane protease activity
ANTHELSMS3_01147	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANTHELSMS3_01148	COG0165	Argininosuccinate lyase
ANTHELSMS3_01151	COG0019	diaminopimelate decarboxylase activity
ANTHELSMS3_01154	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
ANTHELSMS3_01156	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
ANTHELSMS3_01160	COG0514	ATP-dependent DNA helicase (RecQ)
ANTHELSMS3_01161	COG3022	response to hydroperoxide
ANTHELSMS3_01162	COG5002	protein histidine kinase activity
ANTHELSMS3_01162	COG2205	protein histidine kinase activity
ANTHELSMS3_01162	COG0784	Response regulator, receiver
ANTHELSMS3_01163	COG2373	Large extracellular alpha-helical protein
ANTHELSMS3_01165	COG4953	penicillin-binding protein 1C
ANTHELSMS3_01169	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
ANTHELSMS3_01170	COG0156	8-amino-7-oxononanoate synthase activity
ANTHELSMS3_01171	COG0183	Belongs to the thiolase family
ANTHELSMS3_01173	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
ANTHELSMS3_01176	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
ANTHELSMS3_01179	COG0066	3-isopropylmalate dehydratase activity
ANTHELSMS3_01183	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_01184	COG0473	3-isopropylmalate dehydrogenase activity
ANTHELSMS3_01186	COG0697	spore germination
ANTHELSMS3_01192	COG1132	(ABC) transporter
ANTHELSMS3_01193	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANTHELSMS3_01199	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_01207	COG2072	flavoprotein involved in K transport
ANTHELSMS3_01208	COG3284	Transcriptional regulator
ANTHELSMS3_01210	COG0798	PFAM Bile acid sodium symporter
ANTHELSMS3_01211	COG0431	NADPH-dependent FMN reductase
ANTHELSMS3_01212	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_01216	COG1175	transmembrane transport
ANTHELSMS3_01219	COG3734	2-keto-3-deoxy-galactonokinase
ANTHELSMS3_01220	COG0800	Aldolase
ANTHELSMS3_01222	COG1136	(ABC) transporter
ANTHELSMS3_01225	COG2217	Heavy metal translocating P-type atpase
ANTHELSMS3_01226	COG0820	rRNA (adenine-C2-)-methyltransferase activity
ANTHELSMS3_01229	COG3830	Belongs to the UPF0237 family
ANTHELSMS3_01229	COG0560	Phosphoserine phosphatase
ANTHELSMS3_01231	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
ANTHELSMS3_01238	COG0679	Auxin Efflux Carrier
ANTHELSMS3_01239	COG1266	CAAX protease self-immunity
ANTHELSMS3_01240	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
ANTHELSMS3_01241	COG0285	dihydrofolate synthase activity
ANTHELSMS3_01245	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
ANTHELSMS3_01248	COG2423	ornithine cyclodeaminase activity
ANTHELSMS3_01250	COG1671	Belongs to the UPF0178 family
ANTHELSMS3_01251	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
ANTHELSMS3_01252	COG1309	transcriptional regulator
ANTHELSMS3_01255	COG0129	dihydroxy-acid dehydratase activity
ANTHELSMS3_01260	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANTHELSMS3_01261	COG1177	transmembrane transport
ANTHELSMS3_01262	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANTHELSMS3_01263	COG3842	ATPase activity
ANTHELSMS3_01268	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
ANTHELSMS3_01271	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
ANTHELSMS3_01272	COG1322	Protein conserved in bacteria
ANTHELSMS3_01273	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
ANTHELSMS3_01274	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANTHELSMS3_01275	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ANTHELSMS3_01276	COG3806	Anti-sigma factor
ANTHELSMS3_01277	COG1595	DNA-templated transcription, initiation
ANTHELSMS3_01281	COG4221	oxidoreductase activity
ANTHELSMS3_01283	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ANTHELSMS3_01286	COG0284	orotidine-5'-phosphate decarboxylase activity
ANTHELSMS3_01291	COG1475	DNA binding
ANTHELSMS3_01292	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ANTHELSMS3_01294	COG0069	glutamate synthase activity
ANTHELSMS3_01295	COG0076	glutamate decarboxylase activity
ANTHELSMS3_01296	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ANTHELSMS3_01297	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ANTHELSMS3_01307	COG2801	Transposase and inactivated derivatives
ANTHELSMS3_01311	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_01315	COG3547	Transposase (IS116 IS110 IS902 family)
ANTHELSMS3_01321	COG1349	DNA-binding transcription factor activity
ANTHELSMS3_01323	COG1175	transmembrane transport
ANTHELSMS3_01324	COG0395	ABC-type sugar transport system, permease component
ANTHELSMS3_01325	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ANTHELSMS3_01327	COG0402	S-adenosylhomocysteine deaminase activity
ANTHELSMS3_01328	COG3842	ATPase activity
ANTHELSMS3_01329	COG0434	BtpA family
ANTHELSMS3_01332	COG0402	S-adenosylhomocysteine deaminase activity
ANTHELSMS3_01337	COG2801	Transposase and inactivated derivatives
ANTHELSMS3_01340	COG0247	lactate metabolic process
ANTHELSMS3_01340	COG0277	FAD linked oxidase domain protein
ANTHELSMS3_01343	COG1228	amidohydrolase
ANTHELSMS3_01349	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_01350	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ANTHELSMS3_01351	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ANTHELSMS3_01358	COG2186	Transcriptional regulator
ANTHELSMS3_01362	COG3842	ATPase activity
ANTHELSMS3_01364	COG1349	DNA-binding transcription factor activity
ANTHELSMS3_01369	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_01376	COG4608	Belongs to the ABC transporter superfamily
ANTHELSMS3_01377	COG0444	Belongs to the ABC transporter superfamily
ANTHELSMS3_01378	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_01379	COG0601	transmembrane transport
ANTHELSMS3_01381	COG4166	transmembrane transport
ANTHELSMS3_01383	COG3547	Transposase (IS116 IS110 IS902 family)
ANTHELSMS3_01390	COG0582	viral genome integration into host DNA
ANTHELSMS3_01399	COG1872	DUF167
ANTHELSMS3_01407	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
ANTHELSMS3_01408	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ANTHELSMS3_01410	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ANTHELSMS3_01412	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
ANTHELSMS3_01414	COG0793	Belongs to the peptidase S41A family
ANTHELSMS3_01415	COG1051	belongs to the nudix hydrolase family
ANTHELSMS3_01418	COG0557	exoribonuclease II activity
ANTHELSMS3_01421	COG2153	protein acetylation
ANTHELSMS3_01422	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ANTHELSMS3_01426	COG2171	N-acyltransferase activity
ANTHELSMS3_01427	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ANTHELSMS3_01430	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
ANTHELSMS3_01432	COG0288	reversible hydration of carbon dioxide
ANTHELSMS3_01434	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ANTHELSMS3_01435	COG0791	NLP P60 protein
ANTHELSMS3_01438	COG2050	protein possibly involved in aromatic compounds catabolism
ANTHELSMS3_01442	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ANTHELSMS3_01443	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANTHELSMS3_01445	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
ANTHELSMS3_01448	COG1115	amino acid carrier protein
ANTHELSMS3_01453	COG0254	rRNA binding
ANTHELSMS3_01454	COG0335	large ribosomal subunit rRNA binding
ANTHELSMS3_01457	COG0336	Belongs to the RNA methyltransferase TrmD family
ANTHELSMS3_01459	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
ANTHELSMS3_01460	COG0228	four-way junction DNA binding
ANTHELSMS3_01467	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
ANTHELSMS3_01470	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ANTHELSMS3_01477	COG0356	it plays a direct role in the translocation of protons across the membrane
ANTHELSMS3_01478	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
ANTHELSMS3_01479	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ANTHELSMS3_01480	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
ANTHELSMS3_01481	COG1192	Involved in chromosome partitioning
ANTHELSMS3_01488	COG3454	Phosphonate metabolism
ANTHELSMS3_01489	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ANTHELSMS3_01490	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ANTHELSMS3_01497	COG0529	Catalyzes the synthesis of activated sulfate
ANTHELSMS3_01497	COG2046	Belongs to the sulfate adenylyltransferase family
ANTHELSMS3_01499	COG0492	ferredoxin-NADP+ reductase activity
ANTHELSMS3_01500	COG1522	sequence-specific DNA binding
ANTHELSMS3_01505	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
ANTHELSMS3_01507	COG1070	Carbohydrate kinase
ANTHELSMS3_01509	COG1183	phosphatidylcholine synthase activity
ANTHELSMS3_01510	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ANTHELSMS3_01511	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
ANTHELSMS3_01513	COG0564	pseudouridine synthase activity
ANTHELSMS3_01514	COG0546	phosphoglycolate phosphatase activity
ANTHELSMS3_01516	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANTHELSMS3_01519	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
ANTHELSMS3_01520	COG0218	Necessary for normal cell division and for the maintenance of normal septation
ANTHELSMS3_01522	COG0706	membrane insertase activity
ANTHELSMS3_01523	COG3300	MHYT domain
ANTHELSMS3_01523	COG5001	Diguanylate cyclase
ANTHELSMS3_01524	COG0037	tRNA processing
ANTHELSMS3_01526	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
ANTHELSMS3_01527	COG0594	ribonuclease P activity
ANTHELSMS3_01528	COG0230	Belongs to the bacterial ribosomal protein bL34 family
ANTHELSMS3_01531	COG5000	phosphorelay sensor kinase activity
ANTHELSMS3_01535	COG0154	amidase activity
ANTHELSMS3_01537	COG0747	negative chemotaxis
ANTHELSMS3_01539	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_01540	COG4608	Belongs to the ABC transporter superfamily
ANTHELSMS3_01541	COG0444	Belongs to the ABC transporter superfamily
ANTHELSMS3_01542	COG0154	amidase activity
ANTHELSMS3_01545	COG2351	hydroxyisourate hydrolase activity
ANTHELSMS3_01547	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
ANTHELSMS3_01549	COG0402	S-adenosylhomocysteine deaminase activity
ANTHELSMS3_01552	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ANTHELSMS3_01556	COG1858	cytochrome C peroxidase
ANTHELSMS3_01560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
ANTHELSMS3_01561	COG1490	D-aminoacyl-tRNA deacylase activity
ANTHELSMS3_01565	COG4681	YaeQ
ANTHELSMS3_01569	COG3853	Toxic anion resistance protein (TelA)
ANTHELSMS3_01574	COG1187	pseudouridine synthase activity
ANTHELSMS3_01575	COG0590	tRNA wobble adenosine to inosine editing
ANTHELSMS3_01578	COG0408	coproporphyrinogen oxidase activity
ANTHELSMS3_01580	COG2813	Specifically methylates the guanine in position
ANTHELSMS3_01581	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
ANTHELSMS3_01583	COG1686	Belongs to the peptidase S11 family
ANTHELSMS3_01585	COG0828	Belongs to the bacterial ribosomal protein bS21 family
ANTHELSMS3_01589	COG0181	hydroxymethylbilane synthase activity
ANTHELSMS3_01590	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
ANTHELSMS3_01591	COG2391	methyltransferase activity
ANTHELSMS3_01595	COG1017	nitric oxide dioxygenase activity
ANTHELSMS3_01595	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ANTHELSMS3_01599	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
ANTHELSMS3_01600	COG0632	four-way junction helicase activity
ANTHELSMS3_01602	COG2255	four-way junction helicase activity
ANTHELSMS3_01604	COG0180	Tryptophanyl-tRNA synthetase
ANTHELSMS3_01612	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ANTHELSMS3_01614	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
ANTHELSMS3_01615	COG0792	nuclease activity
ANTHELSMS3_01618	COG0606	chelatase, subunit chli
ANTHELSMS3_01620	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ANTHELSMS3_01621	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
ANTHELSMS3_01622	COG0756	dUTP diphosphatase activity
ANTHELSMS3_01623	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
ANTHELSMS3_01624	COG0339	signal peptide processing
ANTHELSMS3_01628	COG0697	spore germination
ANTHELSMS3_01630	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
ANTHELSMS3_01631	COG0459	protein refolding
ANTHELSMS3_01635	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ANTHELSMS3_01636	COG2189	Belongs to the N(4) N(6)-methyltransferase family
ANTHELSMS3_01639	COG0840	transmembrane signaling receptor activity
ANTHELSMS3_01640	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
ANTHELSMS3_01643	COG4143	(ABC) transporter
ANTHELSMS3_01644	COG1178	ABC-type Fe3 transport system permease component
ANTHELSMS3_01645	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
ANTHELSMS3_01651	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
ANTHELSMS3_01654	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_01657	COG3118	belongs to the thioredoxin family
ANTHELSMS3_01660	COG1278	Cold shock
ANTHELSMS3_01665	COG3093	addiction module antidote protein HigA
ANTHELSMS3_01667	COG2801	Transposase and inactivated derivatives
ANTHELSMS3_01681	COG0556	nucleotide-excision repair
ANTHELSMS3_01687	COG0514	ATP-dependent DNA helicase (RecQ)
ANTHELSMS3_01688	COG1064	alcohol dehydrogenase
ANTHELSMS3_01689	COG4948	Mandelate Racemase Muconate Lactonizing
ANTHELSMS3_01690	COG1902	pentaerythritol trinitrate reductase activity
ANTHELSMS3_01690	COG0446	pyridine nucleotide-disulphide oxidoreductase
ANTHELSMS3_01702	COG2801	Transposase and inactivated derivatives
ANTHELSMS3_01703	COG2963	transposase activity
ANTHELSMS3_01704	COG0235	Class ii aldolase
ANTHELSMS3_01711	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANTHELSMS3_01717	COG4651	solute:proton antiporter activity
ANTHELSMS3_01717	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ANTHELSMS3_01719	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_01721	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANTHELSMS3_01722	COG1177	transmembrane transport
ANTHELSMS3_01723	COG3842	ATPase activity
ANTHELSMS3_01725	COG0402	S-adenosylhomocysteine deaminase activity
ANTHELSMS3_01730	COG1304	FMN binding
ANTHELSMS3_01731	COG2186	Transcriptional regulator
ANTHELSMS3_01733	COG2084	Dehydrogenase
ANTHELSMS3_01738	COG1414	Transcriptional regulator
ANTHELSMS3_01744	COG1335	isochorismatase
ANTHELSMS3_01745	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_01747	COG1349	DNA-binding transcription factor activity
ANTHELSMS3_01755	COG4608	Belongs to the ABC transporter superfamily
ANTHELSMS3_01757	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_01758	COG0601	transmembrane transport
ANTHELSMS3_01759	COG1335	isochorismatase
ANTHELSMS3_01760	COG1335	isochorismatase
ANTHELSMS3_01764	COG0765	amino acid transport
ANTHELSMS3_01765	COG0765	amino acid transport
ANTHELSMS3_01769	COG2188	Transcriptional regulator
ANTHELSMS3_01777	COG4191	Histidine kinase
ANTHELSMS3_01783	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_01784	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ANTHELSMS3_01786	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_01787	COG1024	Enoyl-CoA hydratase
ANTHELSMS3_01787	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANTHELSMS3_01788	COG0183	Belongs to the thiolase family
ANTHELSMS3_01791	COG2188	Transcriptional regulator
ANTHELSMS3_01792	COG1454	alcohol dehydrogenase
ANTHELSMS3_01795	COG0559	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_01799	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ANTHELSMS3_01800	COG1741	Belongs to the pirin family
ANTHELSMS3_01805	COG1513	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide
ANTHELSMS3_01807	COG1116	anion transmembrane transporter activity
ANTHELSMS3_01808	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANTHELSMS3_01809	COG1116	anion transmembrane transporter activity
ANTHELSMS3_01809	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANTHELSMS3_01810	COG3604	Transcriptional regulator
ANTHELSMS3_01815	COG0251	oxidation-reduction process
ANTHELSMS3_01825	COG3457	Alanine racemase
ANTHELSMS3_01830	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
ANTHELSMS3_01842	COG0187	DNA topoisomerase II activity
ANTHELSMS3_01846	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
ANTHELSMS3_01849	COG0346	lactoylglutathione lyase activity
ANTHELSMS3_01852	COG1846	Transcriptional regulator
ANTHELSMS3_01854	COG1426	Protein conserved in bacteria
ANTHELSMS3_01860	COG0483	inositol monophosphate 1-phosphatase activity
ANTHELSMS3_01863	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ANTHELSMS3_01863	COG0506	proline dehydrogenase activity
ANTHELSMS3_01863	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
ANTHELSMS3_01864	COG1522	sequence-specific DNA binding
ANTHELSMS3_01868	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ANTHELSMS3_01870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ANTHELSMS3_01871	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ANTHELSMS3_01873	COG2871	sodium ion transport
ANTHELSMS3_01875	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
ANTHELSMS3_01878	COG1702	phosphate starvation-inducible protein PhoH
ANTHELSMS3_01879	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
ANTHELSMS3_01880	COG4535	Mg2 and Co2 transporter CorC
ANTHELSMS3_01881	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ANTHELSMS3_01882	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
ANTHELSMS3_01884	COG0220	tRNA (guanine-N7-)-methyltransferase activity
ANTHELSMS3_01885	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
ANTHELSMS3_01887	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
ANTHELSMS3_01888	COG1609	Transcriptional regulator
ANTHELSMS3_01890	COG0471	metal ion transport
ANTHELSMS3_01890	COG3273	potassium ion transport
ANTHELSMS3_01892	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ANTHELSMS3_01893	COG1126	abc transporter atp-binding protein
ANTHELSMS3_01894	COG0765	amino acid transport
ANTHELSMS3_01904	COG0457	Tetratricopeptide repeat
ANTHELSMS3_01907	COG1802	Transcriptional regulator
ANTHELSMS3_01908	COG4948	Mandelate Racemase Muconate Lactonizing
ANTHELSMS3_01909	COG3842	ATPase activity
ANTHELSMS3_01910	COG4209	transmembrane transport
ANTHELSMS3_01911	COG0395	ABC-type sugar transport system, permease component
ANTHELSMS3_01912	COG1653	transport
ANTHELSMS3_01916	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_01917	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANTHELSMS3_01921	COG2351	hydroxyisourate hydrolase activity
ANTHELSMS3_01922	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
ANTHELSMS3_01925	COG2897	thiosulfate sulfurtransferase activity
ANTHELSMS3_01927	COG0587	DNA-directed DNA polymerase activity
ANTHELSMS3_01931	COG1840	ABC-type Fe3 transport system, periplasmic component
ANTHELSMS3_01933	COG3842	ATPase activity
ANTHELSMS3_01939	COG0469	pyruvate kinase activity
ANTHELSMS3_01941	COG0291	Belongs to the bacterial ribosomal protein bL35 family
ANTHELSMS3_01942	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
ANTHELSMS3_01944	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
ANTHELSMS3_01945	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
ANTHELSMS3_01949	COG0072	phenylalanine-tRNA ligase activity
ANTHELSMS3_01949	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
ANTHELSMS3_01954	COG0488	(ABC) transporter
ANTHELSMS3_01960	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
ANTHELSMS3_01963	COG1192	Involved in chromosome partitioning
ANTHELSMS3_01966	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ANTHELSMS3_01966	COG0616	signal peptide processing
ANTHELSMS3_01969	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_01970	COG0322	excinuclease ABC activity
ANTHELSMS3_01973	COG0730	response to heat
ANTHELSMS3_01979	COG0456	acetyltransferase
ANTHELSMS3_01980	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
ANTHELSMS3_01981	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
ANTHELSMS3_01984	COG2514	catechol 2,3-dioxygenase activity
ANTHELSMS3_01985	COG3383	formate dehydrogenase (NAD+) activity
ANTHELSMS3_01986	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ANTHELSMS3_02000	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
ANTHELSMS3_02004	COG2197	response regulator
ANTHELSMS3_02005	COG0257	Belongs to the bacterial ribosomal protein bL36 family
ANTHELSMS3_02008	COG1663	tetraacyldisaccharide 4'-kinase activity
ANTHELSMS3_02009	COG1519	Transferase
ANTHELSMS3_02012	COG0312	modulator of DNA gyrase
ANTHELSMS3_02014	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
ANTHELSMS3_02015	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
ANTHELSMS3_02020	COG0138	bifunctional purine biosynthesis protein purh
ANTHELSMS3_02021	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ANTHELSMS3_02023	COG0612	Peptidase, M16
ANTHELSMS3_02024	COG0612	Peptidase, M16
ANTHELSMS3_02025	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ANTHELSMS3_02028	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANTHELSMS3_02028	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
ANTHELSMS3_02031	COG2030	dehydratase
ANTHELSMS3_02040	COG0405	Gamma-glutamyltransferase
ANTHELSMS3_02042	COG1366	Belongs to the anti-sigma-factor antagonist family
ANTHELSMS3_02048	COG1280	lysine exporter protein (LysE YggA)
ANTHELSMS3_02051	COG0564	pseudouridine synthase activity
ANTHELSMS3_02052	COG0640	Transcriptional regulator
ANTHELSMS3_02055	COG0450	alkyl hydroperoxide reductase
ANTHELSMS3_02057	COG0708	Exodeoxyribonuclease III
ANTHELSMS3_02059	COG3118	belongs to the thioredoxin family
ANTHELSMS3_02060	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ANTHELSMS3_02061	COG2835	tetraacyldisaccharide 4'-kinase activity
ANTHELSMS3_02063	COG3591	Belongs to the peptidase S1B family
ANTHELSMS3_02068	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
ANTHELSMS3_02072	COG1185	polyribonucleotide nucleotidyltransferase activity
ANTHELSMS3_02075	COG1764	response to oxidative stress
ANTHELSMS3_02076	COG1846	Transcriptional regulator
ANTHELSMS3_02077	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_02079	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ANTHELSMS3_02081	COG3842	ATPase activity
ANTHELSMS3_02084	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANTHELSMS3_02085	COG1177	transmembrane transport
ANTHELSMS3_02088	COG1846	Transcriptional regulator
ANTHELSMS3_02089	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_02090	COG0123	including yeast histone deacetylase and acetoin utilization protein
ANTHELSMS3_02091	COG1722	exodeoxyribonuclease VII activity
ANTHELSMS3_02092	COG0142	geranyltranstransferase activity
ANTHELSMS3_02093	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ANTHELSMS3_02101	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ANTHELSMS3_02102	COG0776	regulation of translation
ANTHELSMS3_02105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ANTHELSMS3_02107	COG1116	anion transmembrane transporter activity
ANTHELSMS3_02108	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANTHELSMS3_02110	COG2884	Cell division ATP-binding protein ftsE
ANTHELSMS3_02118	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANTHELSMS3_02122	COG0045	succinate-CoA ligase (ADP-forming) activity
ANTHELSMS3_02124	COG0039	L-malate dehydrogenase activity
ANTHELSMS3_02127	COG2301	Belongs to the HpcH HpaI aldolase family
ANTHELSMS3_02130	COG2030	dehydratase
ANTHELSMS3_02141	COG0813	purine-nucleoside phosphorylase activity
ANTHELSMS3_02144	COG2937	Belongs to the GPAT DAPAT family
ANTHELSMS3_02149	COG1712	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate
ANTHELSMS3_02150	COG2130	NADP-dependent
ANTHELSMS3_02151	COG0318	PFAM AMP-dependent synthetase and ligase
ANTHELSMS3_02153	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_02158	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANTHELSMS3_02159	COG0772	Belongs to the SEDS family
ANTHELSMS3_02160	COG0768	penicillin binding
ANTHELSMS3_02170	COG0625	glutathione transferase activity
ANTHELSMS3_02171	COG1970	mechanosensitive ion channel activity
ANTHELSMS3_02172	COG0686	Belongs to the AlaDH PNT family
ANTHELSMS3_02173	COG1522	sequence-specific DNA binding
ANTHELSMS3_02177	COG0348	domain, Protein
ANTHELSMS3_02178	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_02181	COG2010	Cytochrome c
ANTHELSMS3_02186	COG0384	phenazine biosynthesis protein PhzF
ANTHELSMS3_02187	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
ANTHELSMS3_02188	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ANTHELSMS3_02189	COG4172	Belongs to the ABC transporter superfamily
ANTHELSMS3_02190	COG4239	(ABC) transporter, permease
ANTHELSMS3_02191	COG4174	ABC transporter (Permease)
ANTHELSMS3_02192	COG4166	transmembrane transport
ANTHELSMS3_02194	COG0077	Prephenate dehydratase
ANTHELSMS3_02194	COG1605	Chorismate mutase
ANTHELSMS3_02197	COG2084	Dehydrogenase
ANTHELSMS3_02202	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ANTHELSMS3_02207	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANTHELSMS3_02209	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ANTHELSMS3_02209	COG0446	pyridine nucleotide-disulphide oxidoreductase
ANTHELSMS3_02212	COG0358	DNA primase activity
ANTHELSMS3_02213	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ANTHELSMS3_02217	COG0432	Pfam Uncharacterised protein family UPF0047
ANTHELSMS3_02221	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ANTHELSMS3_02221	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
ANTHELSMS3_02228	COG2391	methyltransferase activity
ANTHELSMS3_02231	COG0785	Cytochrome C biogenesis protein
ANTHELSMS3_02236	COG3258	Cytochrome c
ANTHELSMS3_02237	COG0737	Belongs to the 5'-nucleotidase family
ANTHELSMS3_02238	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
ANTHELSMS3_02241	COG0446	pyridine nucleotide-disulphide oxidoreductase
ANTHELSMS3_02243	COG0740	serine-type endopeptidase activity
ANTHELSMS3_02244	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
ANTHELSMS3_02252	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
ANTHELSMS3_02253	COG0439	Biotin carboxylase
ANTHELSMS3_02257	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ANTHELSMS3_02258	COG0410	ABC transporter
ANTHELSMS3_02261	COG0559	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_02263	COG3800	Transcriptional regulator
ANTHELSMS3_02263	COG1396	sequence-specific DNA binding
ANTHELSMS3_02264	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_02266	COG5002	protein histidine kinase activity
ANTHELSMS3_02275	COG1305	Transglutaminase-like
ANTHELSMS3_02277	COG2308	Evidence 4 Homologs of previously reported genes of
ANTHELSMS3_02278	COG3750	Belongs to the UPF0335 family
ANTHELSMS3_02290	COG3293	Transposase
ANTHELSMS3_02295	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ANTHELSMS3_02302	COG2132	Multicopper oxidase
ANTHELSMS3_02312	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANTHELSMS3_02313	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_02315	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANTHELSMS3_02316	COG3246	L-lysine catabolic process to acetate
ANTHELSMS3_02318	COG0559	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_02321	COG0410	ABC transporter
ANTHELSMS3_02322	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_02324	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_02325	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_02328	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_02329	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ANTHELSMS3_02330	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANTHELSMS3_02331	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ANTHELSMS3_02332	COG0277	FAD linked oxidase domain protein
ANTHELSMS3_02334	COG2084	Dehydrogenase
ANTHELSMS3_02337	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ANTHELSMS3_02339	COG0129	dihydroxy-acid dehydratase activity
ANTHELSMS3_02341	COG0697	spore germination
ANTHELSMS3_02342	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_02344	COG2721	sulfolactate sulfo-lyase activity
ANTHELSMS3_02348	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ANTHELSMS3_02352	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_02354	COG3958	Transketolase
ANTHELSMS3_02355	COG3959	Transketolase, thiamine diphosphate binding domain
ANTHELSMS3_02357	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_02359	COG3246	L-lysine catabolic process to acetate
ANTHELSMS3_02361	COG0673	inositol 2-dehydrogenase activity
ANTHELSMS3_02363	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_02365	COG1278	Cold shock
ANTHELSMS3_02370	COG3220	belongs to the UPF0276 family
ANTHELSMS3_02372	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
ANTHELSMS3_02377	COG3842	ATPase activity
ANTHELSMS3_02378	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANTHELSMS3_02379	COG1177	transmembrane transport
ANTHELSMS3_02380	COG1349	DNA-binding transcription factor activity
ANTHELSMS3_02382	COG3842	ATPase activity
ANTHELSMS3_02384	COG1175	transmembrane transport
ANTHELSMS3_02385	COG0395	ABC-type sugar transport system, permease component
ANTHELSMS3_02388	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
ANTHELSMS3_02396	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
ANTHELSMS3_02401	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
ANTHELSMS3_02402	COG0625	glutathione transferase activity
ANTHELSMS3_02410	COG1802	Transcriptional regulator
ANTHELSMS3_02420	COG1396	sequence-specific DNA binding
ANTHELSMS3_02421	COG0156	8-amino-7-oxononanoate synthase activity
ANTHELSMS3_02422	COG1063	alcohol dehydrogenase
ANTHELSMS3_02427	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ANTHELSMS3_02429	COG3396	Phenylacetate-CoA oxygenase
ANTHELSMS3_02430	COG3460	Phenylacetate-CoA oxygenase
ANTHELSMS3_02431	COG3396	Phenylacetate-CoA oxygenase
ANTHELSMS3_02432	COG2151	metal-sulfur cluster biosynthetic enzyme
ANTHELSMS3_02433	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
ANTHELSMS3_02435	COG2030	dehydratase
ANTHELSMS3_02435	COG1012	belongs to the aldehyde dehydrogenase family
ANTHELSMS3_02436	COG3327	negative regulation of DNA-templated transcription, initiation
ANTHELSMS3_02438	COG3622	Belongs to the hyi family
ANTHELSMS3_02441	COG2066	Belongs to the glutaminase family
ANTHELSMS3_02443	COG0747	negative chemotaxis
ANTHELSMS3_02445	COG0444	Belongs to the ABC transporter superfamily
ANTHELSMS3_02446	COG4608	Belongs to the ABC transporter superfamily
ANTHELSMS3_02448	COG0747	negative chemotaxis
ANTHELSMS3_02450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_02453	COG0642	Histidine kinase
ANTHELSMS3_02455	COG3181	Tripartite tricarboxylate transporter family receptor
ANTHELSMS3_02461	COG0673	inositol 2-dehydrogenase activity
ANTHELSMS3_02465	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_02467	COG0655	NAD(P)H dehydrogenase (quinone) activity
ANTHELSMS3_02469	COG0697	spore germination
ANTHELSMS3_02478	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ANTHELSMS3_02481	COG4608	Belongs to the ABC transporter superfamily
ANTHELSMS3_02483	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_02484	COG0601	transmembrane transport
ANTHELSMS3_02485	COG4166	transmembrane transport
ANTHELSMS3_02489	COG0699	ATPase. Has a role at an early stage in the morphogenesis of the spore coat
ANTHELSMS3_02491	COG0631	protein serine/threonine phosphatase activity
ANTHELSMS3_02493	COG2815	serine threonine protein kinase
ANTHELSMS3_02493	COG0515	serine threonine protein kinase
ANTHELSMS3_02496	COG0028	Belongs to the TPP enzyme family
ANTHELSMS3_02499	COG3483	tryptophan 2,3-dioxygenase activity
ANTHELSMS3_02503	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ANTHELSMS3_02507	COG0673	inositol 2-dehydrogenase activity
ANTHELSMS3_02514	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ANTHELSMS3_02515	COG1024	Enoyl-CoA hydratase
ANTHELSMS3_02515	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANTHELSMS3_02516	COG5002	protein histidine kinase activity
ANTHELSMS3_02516	COG2176	DNA-directed DNA polymerase activity
ANTHELSMS3_02519	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
ANTHELSMS3_02521	COG0563	adenylate kinase activity
ANTHELSMS3_02522	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ANTHELSMS3_02525	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ANTHELSMS3_02526	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
ANTHELSMS3_02528	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
ANTHELSMS3_02531	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ANTHELSMS3_02532	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
ANTHELSMS3_02536	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
ANTHELSMS3_02538	COG1492	cobalamin metabolic process
ANTHELSMS3_02550	COG2099	Precorrin-6x reductase
ANTHELSMS3_02553	COG2875	Belongs to the precorrin methyltransferase family
ANTHELSMS3_02554	COG1797	cobyrinic acid a,c-diamide synthase activity
ANTHELSMS3_02555	COG1648	precorrin-2 dehydrogenase activity
ANTHELSMS3_02555	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ANTHELSMS3_02561	COG0310	cobalt ion transport
ANTHELSMS3_02565	COG0667	Aldo Keto reductase
ANTHELSMS3_02572	COG0411	ABC transporter
ANTHELSMS3_02574	COG1917	Cupin 2, conserved barrel domain protein
ANTHELSMS3_02576	COG1116	anion transmembrane transporter activity
ANTHELSMS3_02577	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
ANTHELSMS3_02578	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANTHELSMS3_02580	COG1335	isochorismatase
ANTHELSMS3_02583	COG1802	Transcriptional regulator
ANTHELSMS3_02587	COG4948	Mandelate Racemase Muconate Lactonizing
ANTHELSMS3_02590	COG4948	Mandelate Racemase Muconate Lactonizing
ANTHELSMS3_02609	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ANTHELSMS3_02613	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
ANTHELSMS3_02615	COG0354	folic acid binding
ANTHELSMS3_02617	COG1132	(ABC) transporter
ANTHELSMS3_02620	COG1136	(ABC) transporter
ANTHELSMS3_02622	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ANTHELSMS3_02624	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
ANTHELSMS3_02633	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
ANTHELSMS3_02636	COG2323	membrane
ANTHELSMS3_02638	COG0427	acetyl-CoA hydrolase
ANTHELSMS3_02640	COG0183	Belongs to the thiolase family
ANTHELSMS3_02641	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_02642	COG1113	amino acid transport
ANTHELSMS3_02644	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
ANTHELSMS3_02651	COG0673	inositol 2-dehydrogenase activity
ANTHELSMS3_02652	COG1129	ABC transporter
ANTHELSMS3_02653	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_02654	COG1879	ABC-type sugar transport system periplasmic component
ANTHELSMS3_02656	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_02657	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ANTHELSMS3_02663	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ANTHELSMS3_02664	COG2186	Transcriptional regulator
ANTHELSMS3_02669	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ANTHELSMS3_02670	COG0129	dihydroxy-acid dehydratase activity
ANTHELSMS3_02675	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
ANTHELSMS3_02676	COG0709	Synthesizes selenophosphate from selenide and ATP
ANTHELSMS3_02677	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
ANTHELSMS3_02678	COG2201	protein-glutamate methylesterase activity
ANTHELSMS3_02680	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_02681	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
ANTHELSMS3_02684	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_02686	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANTHELSMS3_02686	COG1024	Enoyl-CoA hydratase
ANTHELSMS3_02690	COG0183	Belongs to the thiolase family
ANTHELSMS3_02692	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_02694	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_02695	COG0789	Transcriptional regulator
ANTHELSMS3_02699	COG0534	Mate efflux family protein
ANTHELSMS3_02700	COG1309	transcriptional regulator
ANTHELSMS3_02702	COG0133	tryptophan synthase activity
ANTHELSMS3_02706	COG0193	aminoacyl-tRNA hydrolase activity
ANTHELSMS3_02708	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
ANTHELSMS3_02710	COG1304	FMN binding
ANTHELSMS3_02711	COG0159	tryptophan synthase activity
ANTHELSMS3_02712	COG2326	polyphosphate kinase activity
ANTHELSMS3_02714	COG0534	Mate efflux family protein
ANTHELSMS3_02716	COG0012	GTP binding
ANTHELSMS3_02720	COG0604	alcohol dehydrogenase
ANTHELSMS3_02721	COG0537	adenosine 5'-monophosphoramidase activity
ANTHELSMS3_02722	COG0589	response to stress
ANTHELSMS3_02723	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
ANTHELSMS3_02724	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ANTHELSMS3_02725	COG0415	Belongs to the DNA photolyase family
ANTHELSMS3_02727	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
ANTHELSMS3_02729	COG0494	nUDIX hydrolase
ANTHELSMS3_02735	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
ANTHELSMS3_02735	COG3264	Mechanosensitive ion channel
ANTHELSMS3_02736	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ANTHELSMS3_02742	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
ANTHELSMS3_02747	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
ANTHELSMS3_02749	COG0166	Belongs to the GPI family
ANTHELSMS3_02754	COG1138	Cytochrome C-type biogenesis protein
ANTHELSMS3_02755	COG3088	subunit of a heme lyase
ANTHELSMS3_02757	COG1024	Enoyl-CoA hydratase
ANTHELSMS3_02758	COG0372	Belongs to the citrate synthase family
ANTHELSMS3_02759	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ANTHELSMS3_02760	COG0658	competence protein
ANTHELSMS3_02760	COG2333	competence protein COMEC
ANTHELSMS3_02761	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
ANTHELSMS3_02762	COG0303	'Molybdopterin
ANTHELSMS3_02763	COG0315	cyclic pyranopterin monophosphate synthase activity
ANTHELSMS3_02764	COG0134	indole-3-glycerol-phosphate synthase activity
ANTHELSMS3_02765	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
ANTHELSMS3_02766	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ANTHELSMS3_02771	COG0393	Putative heavy-metal-binding
ANTHELSMS3_02773	COG5012	cobalamin binding
ANTHELSMS3_02775	COG1410	methionine synthase
ANTHELSMS3_02775	COG0646	methionine synthase
ANTHELSMS3_02777	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ANTHELSMS3_02777	COG0519	Catalyzes the synthesis of GMP from XMP
ANTHELSMS3_02778	COG3710	Transcriptional regulator
ANTHELSMS3_02783	COG5598	trimethylamine methyltransferase
ANTHELSMS3_02786	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
ANTHELSMS3_02787	COG2010	Cytochrome c
ANTHELSMS3_02788	COG3909	cytochrome
ANTHELSMS3_02791	COG2867	negative regulation of translational initiation
ANTHELSMS3_02794	COG0004	ammonium transporteR
ANTHELSMS3_02795	COG1546	Belongs to the CinA family
ANTHELSMS3_02797	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ANTHELSMS3_02797	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
ANTHELSMS3_02798	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ANTHELSMS3_02799	COG3852	Histidine kinase
ANTHELSMS3_02800	COG2204	response regulator
ANTHELSMS3_02801	COG5000	phosphorelay sensor kinase activity
ANTHELSMS3_02802	COG2204	response regulator
ANTHELSMS3_02805	COG0569	domain protein
ANTHELSMS3_02806	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ANTHELSMS3_02807	COG1923	regulation of RNA biosynthetic process
ANTHELSMS3_02808	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ANTHELSMS3_02811	COG2084	Dehydrogenase
ANTHELSMS3_02812	COG1530	ribonuclease E activity
ANTHELSMS3_02812	COG1530	ribonuclease E activity
ANTHELSMS3_02814	COG0425	Belongs to the sulfur carrier protein TusA family
ANTHELSMS3_02815	COG0785	Cytochrome C biogenesis protein
ANTHELSMS3_02818	COG3588	fructose-bisphosphate aldolase
ANTHELSMS3_02820	COG2378	regulation of single-species biofilm formation
ANTHELSMS3_02821	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ANTHELSMS3_02822	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
ANTHELSMS3_02823	COG0805	protein transport
ANTHELSMS3_02826	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
ANTHELSMS3_02827	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
ANTHELSMS3_02828	COG4221	oxidoreductase activity
ANTHELSMS3_02833	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
ANTHELSMS3_02839	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
ANTHELSMS3_02840	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ANTHELSMS3_02841	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
ANTHELSMS3_02843	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ANTHELSMS3_02844	COG0418	dihydroorotase activity
ANTHELSMS3_02862	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_02863	COG4335	DNA alkylation repair
ANTHELSMS3_02864	COG0501	Belongs to the peptidase M48B family
ANTHELSMS3_02865	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ANTHELSMS3_02866	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_02869	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
ANTHELSMS3_02872	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
ANTHELSMS3_02873	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
ANTHELSMS3_02876	COG0697	spore germination
ANTHELSMS3_02877	COG0837	glucose binding
ANTHELSMS3_02878	COG2723	6-phospho-beta-galactosidase activity
ANTHELSMS3_02879	COG1609	Transcriptional regulator
ANTHELSMS3_02880	COG1653	transport
ANTHELSMS3_02881	COG1175	transmembrane transport
ANTHELSMS3_02882	COG0395	ABC-type sugar transport system, permease component
ANTHELSMS3_02883	COG0366	Alpha amylase catalytic
ANTHELSMS3_02884	COG3842	ATPase activity
ANTHELSMS3_02894	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
ANTHELSMS3_02898	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_02899	COG0438	transferase activity, transferring glycosyl groups
ANTHELSMS3_02900	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
ANTHELSMS3_02904	COG0517	IMP dehydrogenase activity
ANTHELSMS3_02904	COG0516	GMP reductase activity
ANTHELSMS3_02905	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
ANTHELSMS3_02910	COG3932	Exopolysaccharide synthesis, ExoD
ANTHELSMS3_02914	COG2226	methyltransferase
ANTHELSMS3_02916	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ANTHELSMS3_02920	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
ANTHELSMS3_02922	COG3627	carbon phosphorus lyase activity
ANTHELSMS3_02923	COG4107	phosphonate C-P lyase system protein PhnK
ANTHELSMS3_02924	COG4778	phosphonate C-P lyase system protein PhnL
ANTHELSMS3_02925	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
ANTHELSMS3_02926	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
ANTHELSMS3_02928	COG3639	organic phosphonate transmembrane transporter activity
ANTHELSMS3_02929	COG3639	organic phosphonate transmembrane transporter activity
ANTHELSMS3_02931	COG1162	GTPase activity
ANTHELSMS3_02933	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
ANTHELSMS3_02934	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
ANTHELSMS3_02936	COG0789	Transcriptional regulator
ANTHELSMS3_02938	COG0215	cysteine-tRNA ligase activity
ANTHELSMS3_02939	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ANTHELSMS3_02942	COG2814	Major facilitator Superfamily
ANTHELSMS3_02950	COG0739	heme binding
ANTHELSMS3_02951	COG2833	Protein of unknown function (DUF455)
ANTHELSMS3_02952	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
ANTHELSMS3_02954	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
ANTHELSMS3_02957	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
ANTHELSMS3_02960	COG2945	thiolester hydrolase activity
ANTHELSMS3_02961	COG1959	2 iron, 2 sulfur cluster binding
ANTHELSMS3_02962	COG1104	cysteine desulfurase activity
ANTHELSMS3_02963	COG0719	Fe-S assembly protein
ANTHELSMS3_02965	COG0393	Putative heavy-metal-binding
ANTHELSMS3_02966	COG0396	ATPase activity
ANTHELSMS3_02967	COG0719	Fe-S assembly protein
ANTHELSMS3_02970	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ANTHELSMS3_02971	COG2813	Specifically methylates the guanine in position
ANTHELSMS3_02976	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
ANTHELSMS3_02977	COG1917	Cupin 2, conserved barrel domain protein
ANTHELSMS3_02978	COG0527	aspartate kinase activity
ANTHELSMS3_02982	COG0544	peptidyl-prolyl cis-trans isomerase activity
ANTHELSMS3_02983	COG0359	binds to the 23S rRNA
ANTHELSMS3_02984	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
ANTHELSMS3_02985	COG0360	Binds together with S18 to 16S ribosomal RNA
ANTHELSMS3_02987	COG2353	YceI-like domain
ANTHELSMS3_02989	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
ANTHELSMS3_02993	COG3956	TIGRFAM MazG family protein
ANTHELSMS3_02994	COG1473	amidohydrolase
ANTHELSMS3_02995	COG1473	amidohydrolase
ANTHELSMS3_02996	COG0010	Belongs to the arginase family
ANTHELSMS3_02998	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
ANTHELSMS3_02999	COG2890	protein-(glutamine-N5) methyltransferase activity
ANTHELSMS3_03001	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
ANTHELSMS3_03002	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ANTHELSMS3_03004	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
ANTHELSMS3_03007	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
ANTHELSMS3_03009	COG3577	Aspartyl protease
ANTHELSMS3_03010	COG2095	MarC family integral membrane protein
ANTHELSMS3_03011	COG0488	(ABC) transporter
ANTHELSMS3_03012	COG0105	UTP biosynthetic process
ANTHELSMS3_03016	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
ANTHELSMS3_03020	COG4695	Portal protein
ANTHELSMS3_03037	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANTHELSMS3_03039	COG0022	dehydrogenase e1 component
ANTHELSMS3_03039	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANTHELSMS3_03041	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ANTHELSMS3_03042	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
ANTHELSMS3_03045	COG0126	phosphoglycerate kinase activity
ANTHELSMS3_03046	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ANTHELSMS3_03047	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
ANTHELSMS3_03050	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
ANTHELSMS3_03051	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
ANTHELSMS3_03052	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
ANTHELSMS3_03056	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
ANTHELSMS3_03057	COG0546	phosphoglycolate phosphatase activity
ANTHELSMS3_03061	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_03064	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ANTHELSMS3_03065	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ANTHELSMS3_03070	COG1024	Enoyl-CoA hydratase
ANTHELSMS3_03074	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANTHELSMS3_03075	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANTHELSMS3_03077	COG0649	NAD binding
ANTHELSMS3_03081	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ANTHELSMS3_03081	COG3743	rRNA binding
ANTHELSMS3_03082	COG3743	rRNA binding
ANTHELSMS3_03082	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ANTHELSMS3_03094	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
ANTHELSMS3_03096	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
ANTHELSMS3_03101	COG0713	ATP synthesis coupled electron transport
ANTHELSMS3_03104	COG1007	ATP synthesis coupled electron transport
ANTHELSMS3_03106	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
ANTHELSMS3_03108	COG0513	Belongs to the DEAD box helicase family
ANTHELSMS3_03111	COG0343	queuine tRNA-ribosyltransferase activity
ANTHELSMS3_03115	COG1902	pentaerythritol trinitrate reductase activity
ANTHELSMS3_03116	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ANTHELSMS3_03119	COG4608	Belongs to the ABC transporter superfamily
ANTHELSMS3_03120	COG0444	Belongs to the ABC transporter superfamily
ANTHELSMS3_03121	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_03122	COG0601	transmembrane transport
ANTHELSMS3_03123	COG0747	negative chemotaxis
ANTHELSMS3_03129	COG0811	peptide transport
ANTHELSMS3_03131	COG2329	Antibiotic biosynthesis monooxygenase
ANTHELSMS3_03133	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
ANTHELSMS3_03134	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
ANTHELSMS3_03135	COG4558	Periplasmic binding protein
ANTHELSMS3_03136	COG3720	iron ion transport
ANTHELSMS3_03137	COG1629	transport
ANTHELSMS3_03138	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
ANTHELSMS3_03142	COG0523	cobalamin synthesis protein
ANTHELSMS3_03143	COG0523	cobalamin synthesis protein
ANTHELSMS3_03149	COG4176	ABC-type proline glycine betaine transport system permease component
ANTHELSMS3_03151	COG0673	inositol 2-dehydrogenase activity
ANTHELSMS3_03155	COG4176	ABC-type proline glycine betaine transport system permease component
ANTHELSMS3_03158	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
ANTHELSMS3_03166	COG3743	rRNA binding
ANTHELSMS3_03166	COG0261	This protein binds to 23S rRNA in the presence of protein L20
ANTHELSMS3_03167	COG0211	Belongs to the bacterial ribosomal protein bL27 family
ANTHELSMS3_03169	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
ANTHELSMS3_03170	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
ANTHELSMS3_03171	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
ANTHELSMS3_03176	COG0352	thiamine-phosphate diphosphorylase activity
ANTHELSMS3_03181	COG1612	heme a metabolic process
ANTHELSMS3_03182	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
ANTHELSMS3_03184	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ANTHELSMS3_03185	COG5425	PFAM Usg family protein
ANTHELSMS3_03189	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
ANTHELSMS3_03194	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ANTHELSMS3_03196	COG0248	Ppx GppA phosphatase
ANTHELSMS3_03197	COG5507	3-demethylubiquinone-9 3-methyltransferase
ANTHELSMS3_03198	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
ANTHELSMS3_03202	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_03203	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANTHELSMS3_03203	COG0824	Thioesterase
ANTHELSMS3_03210	COG1595	DNA-templated transcription, initiation
ANTHELSMS3_03211	COG0156	8-amino-7-oxononanoate synthase activity
ANTHELSMS3_03213	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
ANTHELSMS3_03217	COG0436	Aminotransferase
ANTHELSMS3_03219	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
ANTHELSMS3_03220	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ANTHELSMS3_03236	COG0513	Belongs to the DEAD box helicase family
ANTHELSMS3_03237	COG0626	cystathionine gamma-synthase activity
ANTHELSMS3_03253	COG0542	response to heat
ANTHELSMS3_03254	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
ANTHELSMS3_03256	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
ANTHELSMS3_03258	COG4106	trans-aconitate 2-methyltransferase activity
ANTHELSMS3_03259	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ANTHELSMS3_03263	COG0175	sulfate reduction
ANTHELSMS3_03264	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
ANTHELSMS3_03266	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
ANTHELSMS3_03266	COG1648	precorrin-2 dehydrogenase activity
ANTHELSMS3_03267	COG1522	sequence-specific DNA binding
ANTHELSMS3_03268	COG2124	cytochrome p450
ANTHELSMS3_03272	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ANTHELSMS3_03273	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
ANTHELSMS3_03274	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ANTHELSMS3_03277	COG0149	triose-phosphate isomerase activity
ANTHELSMS3_03280	COG0316	Belongs to the HesB IscA family
ANTHELSMS3_03283	COG2814	Major facilitator Superfamily
ANTHELSMS3_03284	COG2151	metal-sulfur cluster biosynthetic enzyme
ANTHELSMS3_03286	COG0189	ligase activity
ANTHELSMS3_03286	COG4067	protein conserved in archaea
ANTHELSMS3_03292	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ANTHELSMS3_03293	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
ANTHELSMS3_03295	COG0482	sulfurtransferase activity
ANTHELSMS3_03298	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ANTHELSMS3_03303	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
ANTHELSMS3_03304	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
ANTHELSMS3_03305	COG2264	protein methyltransferase activity
ANTHELSMS3_03306	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
ANTHELSMS3_03307	COG1024	Enoyl-CoA hydratase
ANTHELSMS3_03310	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
ANTHELSMS3_03311	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
ANTHELSMS3_03314	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
ANTHELSMS3_03315	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
ANTHELSMS3_03318	COG1309	transcriptional regulator
ANTHELSMS3_03319	COG2326	polyphosphate kinase activity
ANTHELSMS3_03320	COG2267	carboxylic ester hydrolase activity
ANTHELSMS3_03321	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
ANTHELSMS3_03325	COG0697	spore germination
ANTHELSMS3_03327	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
ANTHELSMS3_03330	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ANTHELSMS3_03331	COG0047	phosphoribosylformylglycinamidine synthase activity
ANTHELSMS3_03333	COG2204	response regulator
ANTHELSMS3_03337	COG2354	Protein conserved in bacteria
ANTHELSMS3_03339	COG0433	COG0433 Predicted ATPase
ANTHELSMS3_03341	COG2832	Protein of unknown function (DUF454)
ANTHELSMS3_03346	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
ANTHELSMS3_03347	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
ANTHELSMS3_03348	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
ANTHELSMS3_03350	COG2166	iron-sulfur cluster assembly
ANTHELSMS3_03352	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
ANTHELSMS3_03355	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
ANTHELSMS3_03356	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
ANTHELSMS3_03357	COG0259	pyridoxamine-phosphate oxidase activity
ANTHELSMS3_03362	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ANTHELSMS3_03364	COG2856	Zn peptidase
ANTHELSMS3_03368	COG0538	isocitrate dehydrogenase activity
ANTHELSMS3_03369	COG0840	transmembrane signaling receptor activity
ANTHELSMS3_03370	COG2814	Major facilitator Superfamily
ANTHELSMS3_03383	COG2133	pyrroloquinoline quinone binding
ANTHELSMS3_03384	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ANTHELSMS3_03386	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
ANTHELSMS3_03391	COG1561	YicC-like family, N-terminal region
ANTHELSMS3_03392	COG0194	GDP metabolic process
ANTHELSMS3_03396	COG5002	protein histidine kinase activity
ANTHELSMS3_03398	COG0573	inorganic phosphate transmembrane transporter activity
ANTHELSMS3_03400	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ANTHELSMS3_03401	COG0704	Plays a role in the regulation of phosphate uptake
ANTHELSMS3_03402	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_03404	COG0052	Belongs to the universal ribosomal protein uS2 family
ANTHELSMS3_03405	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
ANTHELSMS3_03407	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ANTHELSMS3_03409	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_03410	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_03412	COG2313	pseudouridylate synthase activity
ANTHELSMS3_03415	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_03416	COG4166	transmembrane transport
ANTHELSMS3_03418	COG2205	protein histidine kinase activity
ANTHELSMS3_03438	COG3321	synthase
ANTHELSMS3_03438	COG0604	alcohol dehydrogenase
ANTHELSMS3_03439	COG3321	synthase
ANTHELSMS3_03439	COG0604	alcohol dehydrogenase
ANTHELSMS3_03442	COG3321	synthase
ANTHELSMS3_03442	COG0604	alcohol dehydrogenase
ANTHELSMS3_03455	COG4214	carbohydrate transport
ANTHELSMS3_03461	COG1129	ABC transporter
ANTHELSMS3_03462	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_03464	COG0673	inositol 2-dehydrogenase activity
ANTHELSMS3_03465	COG3618	amidohydrolase
ANTHELSMS3_03472	COG2059	Chromate
ANTHELSMS3_03474	COG0114	fumarate hydratase activity
ANTHELSMS3_03477	COG3842	ATPase activity
ANTHELSMS3_03480	COG0129	dihydroxy-acid dehydratase activity
ANTHELSMS3_03481	COG0800	Aldolase
ANTHELSMS3_03483	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
ANTHELSMS3_03487	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
ANTHELSMS3_03489	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ANTHELSMS3_03491	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ANTHELSMS3_03492	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_03497	COG0028	Belongs to the TPP enzyme family
ANTHELSMS3_03500	COG0440	acetolactate synthase activity
ANTHELSMS3_03507	COG1129	ABC transporter
ANTHELSMS3_03508	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_03509	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_03510	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_03511	COG1879	ABC-type sugar transport system periplasmic component
ANTHELSMS3_03514	COG0006	proline dipeptidase activity
ANTHELSMS3_03515	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
ANTHELSMS3_03516	COG0022	dehydrogenase e1 component
ANTHELSMS3_03517	COG0508	dehydrogenase complex catalyzes the overall conversion of
ANTHELSMS3_03517	COG0022	dehydrogenase e1 component
ANTHELSMS3_03520	COG0577	efflux transmembrane transporter activity
ANTHELSMS3_03520	COG1136	(ABC) transporter
ANTHELSMS3_03525	COG0405	Gamma-glutamyltransferase
ANTHELSMS3_03531	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ANTHELSMS3_03532	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
ANTHELSMS3_03533	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANTHELSMS3_03537	COG0542	response to heat
ANTHELSMS3_03541	COG3300	MHYT domain
ANTHELSMS3_03541	COG5001	Diguanylate cyclase
ANTHELSMS3_03543	COG1305	Transglutaminase-like
ANTHELSMS3_03544	COG2307	Protein conserved in bacteria
ANTHELSMS3_03544	COG2308	Evidence 4 Homologs of previously reported genes of
ANTHELSMS3_03546	COG0840	transmembrane signaling receptor activity
ANTHELSMS3_03554	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
ANTHELSMS3_03555	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
ANTHELSMS3_03559	COG3386	PFAM SMP-30 Gluconolaconase
ANTHELSMS3_03560	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANTHELSMS3_03563	COG0778	Nitroreductase
ANTHELSMS3_03567	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ANTHELSMS3_03577	COG0333	Belongs to the bacterial ribosomal protein bL32 family
ANTHELSMS3_03578	COG0416	fatty acid biosynthetic process
ANTHELSMS3_03579	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
ANTHELSMS3_03580	COG0776	regulation of translation
ANTHELSMS3_03583	COG0717	Belongs to the dCTP deaminase family
ANTHELSMS3_03585	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ANTHELSMS3_03586	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ANTHELSMS3_03587	COG1472	Belongs to the glycosyl hydrolase 3 family
ANTHELSMS3_03589	COG0018	arginyl-trna synthetase
ANTHELSMS3_03590	COG3263	regulation of cellular component size
ANTHELSMS3_03591	COG0232	Belongs to the dGTPase family. Type 2 subfamily
ANTHELSMS3_03599	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
ANTHELSMS3_03603	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
ANTHELSMS3_03604	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ANTHELSMS3_03605	COG3494	Protein of unknown function (DUF1009)
ANTHELSMS3_03606	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
ANTHELSMS3_03607	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
ANTHELSMS3_03609	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ANTHELSMS3_03611	COG0750	zinc metalloprotease
ANTHELSMS3_03612	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
ANTHELSMS3_03615	COG0233	cytoplasmic translational termination
ANTHELSMS3_03616	COG4977	sequence-specific DNA binding
ANTHELSMS3_03616	COG1917	Cupin 2, conserved barrel domain protein
ANTHELSMS3_03617	COG0528	UMP kinase activity
ANTHELSMS3_03622	COG0601	transmembrane transport
ANTHELSMS3_03627	COG0741	lytic transglycosylase activity
ANTHELSMS3_03628	COG0629	single-stranded DNA binding
ANTHELSMS3_03629	COG0517	IMP dehydrogenase activity
ANTHELSMS3_03629	COG1994	Peptidase M50
ANTHELSMS3_03630	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
ANTHELSMS3_03631	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
ANTHELSMS3_03634	COG4974	Belongs to the 'phage' integrase family
ANTHELSMS3_03635	COG4536	flavin adenine dinucleotide binding
ANTHELSMS3_03646	COG0010	Belongs to the arginase family
ANTHELSMS3_03651	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
ANTHELSMS3_03653	COG1335	isochorismatase
ANTHELSMS3_03656	COG3842	ATPase activity
ANTHELSMS3_03660	COG0402	S-adenosylhomocysteine deaminase activity
ANTHELSMS3_03666	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ANTHELSMS3_03667	COG0174	glutamine synthetase
ANTHELSMS3_03668	COG1012	belongs to the aldehyde dehydrogenase family
ANTHELSMS3_03671	COG1473	amidohydrolase
ANTHELSMS3_03672	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANTHELSMS3_03674	COG4172	Belongs to the ABC transporter superfamily
ANTHELSMS3_03675	COG0747	negative chemotaxis
ANTHELSMS3_03676	COG0601	transmembrane transport
ANTHELSMS3_03677	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_03678	COG2391	methyltransferase activity
ANTHELSMS3_03681	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ANTHELSMS3_03695	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANTHELSMS3_03697	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ANTHELSMS3_03698	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
ANTHELSMS3_03699	COG4133	protoheme IX ABC transporter activity
ANTHELSMS3_03700	COG3737	Protein of unknown function (DUF498/DUF598)
ANTHELSMS3_03702	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ANTHELSMS3_03703	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
ANTHELSMS3_03706	COG3591	Belongs to the peptidase S1B family
ANTHELSMS3_03707	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
ANTHELSMS3_03711	COG1160	GTP binding
ANTHELSMS3_03715	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ANTHELSMS3_03718	COG0308	aminopeptidase N
ANTHELSMS3_03719	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_03724	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ANTHELSMS3_03726	COG0484	heat shock protein binding
ANTHELSMS3_03728	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
ANTHELSMS3_03729	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
ANTHELSMS3_03730	COG1760	l-serine dehydratase
ANTHELSMS3_03734	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
ANTHELSMS3_03739	COG2864	formate dehydrogenase
ANTHELSMS3_03740	COG0437	4 iron, 4 sulfur cluster binding
ANTHELSMS3_03749	COG0489	protein tyrosine kinase activity
ANTHELSMS3_03752	COG3852	Histidine kinase
ANTHELSMS3_03762	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ANTHELSMS3_03764	COG2183	response to ionizing radiation
ANTHELSMS3_03769	COG0544	peptidyl-prolyl cis-trans isomerase activity
ANTHELSMS3_03770	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
ANTHELSMS3_03777	COG0006	proline dipeptidase activity
ANTHELSMS3_03783	COG2223	nitrite transmembrane transporter activity
ANTHELSMS3_03785	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
ANTHELSMS3_03791	COG1309	transcriptional regulator
ANTHELSMS3_03793	COG1529	Aldehyde oxidase and xanthine dehydrogenase
ANTHELSMS3_03793	COG2010	Cytochrome c
ANTHELSMS3_03794	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ANTHELSMS3_03795	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
ANTHELSMS3_03797	COG5265	(ABC) transporter
ANTHELSMS3_03800	COG2962	Rard protein
ANTHELSMS3_03806	COG0446	pyridine nucleotide-disulphide oxidoreductase
ANTHELSMS3_03806	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ANTHELSMS3_03809	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANTHELSMS3_03811	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
ANTHELSMS3_03815	COG0730	response to heat
ANTHELSMS3_03816	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
ANTHELSMS3_03819	COG2828	Protein conserved in bacteria
ANTHELSMS3_03823	COG0642	Histidine kinase
ANTHELSMS3_03824	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_03827	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
ANTHELSMS3_03828	COG0702	epimerase
ANTHELSMS3_03829	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_03832	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANTHELSMS3_03833	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANTHELSMS3_03833	COG1116	anion transmembrane transporter activity
ANTHELSMS3_03838	COG0189	ligase activity
ANTHELSMS3_03848	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
ANTHELSMS3_03868	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
ANTHELSMS3_03872	COG3239	Fatty acid desaturase
ANTHELSMS3_03880	COG0590	tRNA wobble adenosine to inosine editing
ANTHELSMS3_03881	COG4608	Belongs to the ABC transporter superfamily
ANTHELSMS3_03882	COG0444	Belongs to the ABC transporter superfamily
ANTHELSMS3_03883	COG0402	S-adenosylhomocysteine deaminase activity
ANTHELSMS3_03885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_03887	COG0747	negative chemotaxis
ANTHELSMS3_03888	COG2186	Transcriptional regulator
ANTHELSMS3_03889	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
ANTHELSMS3_03901	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ANTHELSMS3_03906	COG0783	Belongs to the Dps family
ANTHELSMS3_03912	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_03914	COG0318	PFAM AMP-dependent synthetase and ligase
ANTHELSMS3_03918	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ANTHELSMS3_03928	COG2132	Multicopper oxidase
ANTHELSMS3_03932	COG2010	Cytochrome c
ANTHELSMS3_03934	COG0714	Associated with various cellular activities
ANTHELSMS3_03943	COG0351	phosphomethylpyrimidine kinase
ANTHELSMS3_03946	COG2022	thiamine diphosphate biosynthetic process
ANTHELSMS3_03949	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
ANTHELSMS3_03950	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ANTHELSMS3_03951	COG1116	anion transmembrane transporter activity
ANTHELSMS3_03953	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ANTHELSMS3_03967	COG3547	Transposase (IS116 IS110 IS902 family)
ANTHELSMS3_03969	COG2801	Transposase and inactivated derivatives
ANTHELSMS3_03973	COG0321	lipoyl(octanoyl) transferase activity
ANTHELSMS3_03981	COG0505	Belongs to the CarA family
ANTHELSMS3_03983	COG1802	Transcriptional regulator
ANTHELSMS3_03997	COG0752	glycyl-tRNA synthetase alpha subunit
ANTHELSMS3_03999	COG0751	glycine-tRNA ligase activity
ANTHELSMS3_04000	COG0574	Belongs to the PEP-utilizing enzyme family
ANTHELSMS3_04000	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ANTHELSMS3_04002	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
ANTHELSMS3_04003	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
ANTHELSMS3_04008	COG0442	prolyl-tRNA aminoacylation
ANTHELSMS3_04010	COG0628	permease
ANTHELSMS3_04012	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ANTHELSMS3_04015	COG0248	Ppx GppA phosphatase
ANTHELSMS3_04018	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
ANTHELSMS3_04026	COG0439	Biotin carboxylase
ANTHELSMS3_04033	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ANTHELSMS3_04034	COG2814	Major facilitator Superfamily
ANTHELSMS3_04035	COG1396	sequence-specific DNA binding
ANTHELSMS3_04035	COG3800	Transcriptional regulator
ANTHELSMS3_04038	COG0154	amidase activity
ANTHELSMS3_04039	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
ANTHELSMS3_04041	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
ANTHELSMS3_04047	COG2968	Membrane
ANTHELSMS3_04050	COG1522	sequence-specific DNA binding
ANTHELSMS3_04051	COG0210	DNA helicase
ANTHELSMS3_04055	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
ANTHELSMS3_04057	COG0346	lactoylglutathione lyase activity
ANTHELSMS3_04061	COG0131	Imidazoleglycerol-phosphate dehydratase
ANTHELSMS3_04062	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
ANTHELSMS3_04065	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
ANTHELSMS3_04067	COG0107	imidazoleglycerol-phosphate synthase activity
ANTHELSMS3_04068	COG0140	phosphoribosyl-ATP diphosphatase activity
ANTHELSMS3_04079	COG0552	protein localization to endoplasmic reticulum
ANTHELSMS3_04083	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_04085	COG0670	Belongs to the BI1 family
ANTHELSMS3_04087	COG0267	Belongs to the bacterial ribosomal protein bL33 family
ANTHELSMS3_04089	COG2267	carboxylic ester hydrolase activity
ANTHELSMS3_04100	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ANTHELSMS3_04102	COG1024	Enoyl-CoA hydratase
ANTHELSMS3_04106	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_04109	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ANTHELSMS3_04114	COG0589	response to stress
ANTHELSMS3_04116	COG0729	surface antigen
ANTHELSMS3_04117	COG1309	transcriptional regulator
ANTHELSMS3_04121	COG0668	transmembrane transport
ANTHELSMS3_04135	COG2423	ornithine cyclodeaminase activity
ANTHELSMS3_04136	COG3214	Protein conserved in bacteria
ANTHELSMS3_04137	COG0179	Fumarylacetoacetate (FAA) hydrolase
ANTHELSMS3_04140	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
ANTHELSMS3_04143	COG0346	lactoylglutathione lyase activity
ANTHELSMS3_04145	COG0459	protein refolding
ANTHELSMS3_04151	COG3350	monooxygenase activity
ANTHELSMS3_04160	COG3257	ureidoglycine aminohydrolase activity
ANTHELSMS3_04161	COG1414	Transcriptional regulator
ANTHELSMS3_04163	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ANTHELSMS3_04168	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
ANTHELSMS3_04170	COG2351	hydroxyisourate hydrolase activity
ANTHELSMS3_04171	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_04173	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_04174	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANTHELSMS3_04179	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ANTHELSMS3_04180	COG3246	L-lysine catabolic process to acetate
ANTHELSMS3_04182	COG0784	Response regulator, receiver
ANTHELSMS3_04182	COG4191	Histidine kinase
ANTHELSMS3_04184	COG1686	Belongs to the peptidase S11 family
ANTHELSMS3_04185	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
ANTHELSMS3_04187	COG0489	protein tyrosine kinase activity
ANTHELSMS3_04189	COG0525	valine-tRNA ligase activity
ANTHELSMS3_04192	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ANTHELSMS3_04194	COG1469	GTP cyclohydrolase I activity
ANTHELSMS3_04200	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
ANTHELSMS3_04207	COG1793	dna ligase
ANTHELSMS3_04213	COG0386	Belongs to the glutathione peroxidase family
ANTHELSMS3_04217	COG1012	belongs to the aldehyde dehydrogenase family
ANTHELSMS3_04218	COG3119	arylsulfatase activity
ANTHELSMS3_04219	COG1309	transcriptional regulator
ANTHELSMS3_04226	COG3920	Histidine kinase
ANTHELSMS3_04227	COG0217	transcriptional regulatory protein
ANTHELSMS3_04229	COG3273	potassium ion transport
ANTHELSMS3_04229	COG0471	metal ion transport
ANTHELSMS3_04231	COG1692	metallophosphoesterase
ANTHELSMS3_04235	COG0587	DNA-directed DNA polymerase activity
ANTHELSMS3_04239	COG0330	HflC and HflK could
ANTHELSMS3_04240	COG0330	HflC and HflK could
ANTHELSMS3_04243	COG0659	secondary active sulfate transmembrane transporter activity
ANTHELSMS3_04244	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
ANTHELSMS3_04252	COG0006	proline dipeptidase activity
ANTHELSMS3_04255	COG3103	Sh3 type 3 domain protein
ANTHELSMS3_04255	COG1388	LysM domain
ANTHELSMS3_04255	COG0791	NLP P60 protein
ANTHELSMS3_04257	COG0277	FAD linked oxidase domain protein
ANTHELSMS3_04259	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
ANTHELSMS3_04260	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
ANTHELSMS3_04261	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ANTHELSMS3_04262	COG0849	cell division
ANTHELSMS3_04263	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
ANTHELSMS3_04264	COG1181	Belongs to the D-alanine--D-alanine ligase family
ANTHELSMS3_04265	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ANTHELSMS3_04268	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
ANTHELSMS3_04269	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
ANTHELSMS3_04271	COG2081	HI0933 family
ANTHELSMS3_04272	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
ANTHELSMS3_04273	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ANTHELSMS3_04275	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
ANTHELSMS3_04278	COG0275	rRNA processing
ANTHELSMS3_04279	COG2001	Belongs to the MraZ family
ANTHELSMS3_04280	COG0811	peptide transport
ANTHELSMS3_04284	COG0084	hydrolase, TatD family'
ANTHELSMS3_04285	COG0321	lipoyl(octanoyl) transferase activity
ANTHELSMS3_04285	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
ANTHELSMS3_04287	COG0697	spore germination
ANTHELSMS3_04289	COG2239	Acts as a magnesium transporter
ANTHELSMS3_04290	COG0402	S-adenosylhomocysteine deaminase activity
ANTHELSMS3_04295	COG0504	CTP synthase activity
ANTHELSMS3_04298	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
ANTHELSMS3_04304	COG4215	(ABC) transporter
ANTHELSMS3_04305	COG4160	amino acid transport
ANTHELSMS3_04307	COG0174	glutamine synthetase
ANTHELSMS3_04308	COG0518	GMP synthase (glutamine-hydrolyzing) activity
ANTHELSMS3_04308	COG0519	Catalyzes the synthesis of GMP from XMP
ANTHELSMS3_04309	COG0174	glutamine synthetase
ANTHELSMS3_04310	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANTHELSMS3_04311	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
ANTHELSMS3_04313	COG1570	exodeoxyribonuclease VII activity
ANTHELSMS3_04314	COG0151	Belongs to the GarS family
ANTHELSMS3_04320	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
ANTHELSMS3_04322	COG2340	Cysteine-rich secretory protein family
ANTHELSMS3_04324	COG0483	inositol monophosphate 1-phosphatase activity
ANTHELSMS3_04329	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ANTHELSMS3_04332	COG0564	pseudouridine synthase activity
ANTHELSMS3_04334	COG3971	2-oxopent-4-enoate hydratase activity
ANTHELSMS3_04335	COG0179	Fumarylacetoacetate (FAA) hydrolase
ANTHELSMS3_04338	COG1846	Transcriptional regulator
ANTHELSMS3_04347	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ANTHELSMS3_04349	COG1024	Enoyl-CoA hydratase
ANTHELSMS3_04350	COG0456	acetyltransferase
ANTHELSMS3_04359	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
ANTHELSMS3_04360	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
ANTHELSMS3_04361	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ANTHELSMS3_04361	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
ANTHELSMS3_04365	COG1108	ABC-type Mn2 Zn2 transport systems permease components
ANTHELSMS3_04366	COG1121	(ABC) transporter
ANTHELSMS3_04368	COG4531	ABC-type Zn2 transport system, periplasmic component surface adhesin
ANTHELSMS3_04369	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
ANTHELSMS3_04371	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
ANTHELSMS3_04373	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
ANTHELSMS3_04374	COG1530	ribonuclease E activity
ANTHELSMS3_04376	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
ANTHELSMS3_04377	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
ANTHELSMS3_04381	COG5328	Belongs to the UPF0262 family
ANTHELSMS3_04385	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ANTHELSMS3_04388	COG1519	Transferase
ANTHELSMS3_04390	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_04393	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
ANTHELSMS3_04398	COG0659	secondary active sulfate transmembrane transporter activity
ANTHELSMS3_04399	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
ANTHELSMS3_04401	COG1280	lysine exporter protein (LysE YggA)
ANTHELSMS3_04412	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ANTHELSMS3_04414	COG0758	DNA mediated transformation
ANTHELSMS3_04415	COG0312	modulator of DNA gyrase
ANTHELSMS3_04417	COG0109	protoheme IX farnesyltransferase activity
ANTHELSMS3_04419	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
ANTHELSMS3_04421	COG3346	SURF1 family
ANTHELSMS3_04423	COG0612	Peptidase, M16
ANTHELSMS3_04426	COG0277	FAD linked oxidase domain protein
ANTHELSMS3_04432	COG4964	Belongs to the GSP D family
ANTHELSMS3_04446	COG3794	PFAM blue (type 1) copper domain protein
ANTHELSMS3_04450	COG1136	(ABC) transporter
ANTHELSMS3_04451	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ANTHELSMS3_04452	COG0006	proline dipeptidase activity
ANTHELSMS3_04456	COG1063	alcohol dehydrogenase
ANTHELSMS3_04457	COG4221	oxidoreductase activity
ANTHELSMS3_04460	COG0546	phosphoglycolate phosphatase activity
ANTHELSMS3_04460	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
ANTHELSMS3_04461	COG3622	Belongs to the hyi family
ANTHELSMS3_04469	COG0673	inositol 2-dehydrogenase activity
ANTHELSMS3_04472	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ANTHELSMS3_04475	COG0601	transmembrane transport
ANTHELSMS3_04476	COG0747	negative chemotaxis
ANTHELSMS3_04477	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_04480	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
ANTHELSMS3_04481	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ANTHELSMS3_04482	COG1454	alcohol dehydrogenase
ANTHELSMS3_04483	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
ANTHELSMS3_04484	COG2186	Transcriptional regulator
ANTHELSMS3_04485	COG3395	kinase activity
ANTHELSMS3_04486	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_04487	COG1802	Transcriptional regulator
ANTHELSMS3_04488	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ANTHELSMS3_04494	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ANTHELSMS3_04497	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ANTHELSMS3_04498	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ANTHELSMS3_04500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ANTHELSMS3_04501	COG1012	belongs to the aldehyde dehydrogenase family
ANTHELSMS3_04513	COG0546	phosphoglycolate phosphatase activity
ANTHELSMS3_04515	COG3706	GGDEF domain
ANTHELSMS3_04515	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_04522	COG0596	Alpha beta hydrolase
ANTHELSMS3_04523	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_04525	COG2515	1-aminocyclopropane-1-carboxylate deaminase
ANTHELSMS3_04528	COG0457	Tetratricopeptide repeat
ANTHELSMS3_04531	COG0481	GTPase activity
ANTHELSMS3_04533	COG1943	Transposase
ANTHELSMS3_04537	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ANTHELSMS3_04542	COG0227	Belongs to the bacterial ribosomal protein bL28 family
ANTHELSMS3_04543	COG1703	isobutyryl-CoA mutase activity
ANTHELSMS3_04544	COG1643	Atp-dependent helicase
ANTHELSMS3_04545	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
ANTHELSMS3_04546	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
ANTHELSMS3_04549	COG1473	amidohydrolase
ANTHELSMS3_04554	COG0101	tRNA pseudouridine synthase activity
ANTHELSMS3_04555	COG3106	COG3106 Predicted ATPase
ANTHELSMS3_04557	COG3768	UPF0283 membrane protein
ANTHELSMS3_04562	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
ANTHELSMS3_04565	COG2197	response regulator
ANTHELSMS3_04567	COG0318	PFAM AMP-dependent synthetase and ligase
ANTHELSMS3_04568	COG1720	tRNA m6t6A37 methyltransferase activity
ANTHELSMS3_04569	COG0688	phosphatidylethanolamine metabolic process
ANTHELSMS3_04575	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ANTHELSMS3_04576	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
ANTHELSMS3_04582	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
ANTHELSMS3_04597	COG2186	Transcriptional regulator
ANTHELSMS3_04598	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ANTHELSMS3_04600	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ANTHELSMS3_04601	COG1335	isochorismatase
ANTHELSMS3_04603	COG1177	transmembrane transport
ANTHELSMS3_04604	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANTHELSMS3_04606	COG3842	ATPase activity
ANTHELSMS3_04607	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
ANTHELSMS3_04608	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_04610	COG1177	transmembrane transport
ANTHELSMS3_04611	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANTHELSMS3_04612	COG3842	ATPase activity
ANTHELSMS3_04614	COG0019	diaminopimelate decarboxylase activity
ANTHELSMS3_04616	COG2226	methyltransferase
ANTHELSMS3_04622	COG3609	addiction module antidote protein, CC2985 family
ANTHELSMS3_04623	COG1414	Transcriptional regulator
ANTHELSMS3_04625	COG1192	Involved in chromosome partitioning
ANTHELSMS3_04634	COG0443	Heat shock 70 kDa protein
ANTHELSMS3_04635	COG0210	DNA helicase
ANTHELSMS3_04650	COG0154	amidase activity
ANTHELSMS3_04652	COG5285	phytanoyl-CoA dioxygenase
ANTHELSMS3_04657	COG1414	Transcriptional regulator
ANTHELSMS3_04664	COG1682	transport, permease protein
ANTHELSMS3_04670	COG1192	Involved in chromosome partitioning
ANTHELSMS3_04674	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
ANTHELSMS3_04674	COG0662	Cupin 2, conserved barrel domain protein
ANTHELSMS3_04677	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ANTHELSMS3_04680	COG1132	(ABC) transporter
ANTHELSMS3_04688	COG1132	(ABC) transporter
ANTHELSMS3_04691	COG1442	glycosyl transferase family 8
ANTHELSMS3_04691	COG1216	Glycosyl transferase, family 2
ANTHELSMS3_04693	COG1215	transferase activity, transferring glycosyl groups
ANTHELSMS3_04695	COG0438	transferase activity, transferring glycosyl groups
ANTHELSMS3_04698	COG0489	protein tyrosine kinase activity
ANTHELSMS3_04699	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
ANTHELSMS3_04701	COG1216	Glycosyl transferase, family 2
ANTHELSMS3_04723	COG2801	Transposase and inactivated derivatives
ANTHELSMS3_04724	COG2801	Transposase and inactivated derivatives
ANTHELSMS3_04728	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ANTHELSMS3_04729	COG2186	Transcriptional regulator
ANTHELSMS3_04730	COG2186	Transcriptional regulator
ANTHELSMS3_04733	COG0404	The glycine cleavage system catalyzes the degradation of glycine
ANTHELSMS3_04734	COG0604	alcohol dehydrogenase
ANTHELSMS3_04739	COG3181	Tripartite tricarboxylate transporter family receptor
ANTHELSMS3_04743	COG1309	transcriptional regulator
ANTHELSMS3_04749	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ANTHELSMS3_04754	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
ANTHELSMS3_04757	COG3347	Dehydrogenase
ANTHELSMS3_04757	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_04758	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ANTHELSMS3_04761	COG0028	Belongs to the TPP enzyme family
ANTHELSMS3_04762	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_04763	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_04769	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ANTHELSMS3_04772	COG0473	3-isopropylmalate dehydrogenase activity
ANTHELSMS3_04774	COG3547	Transposase (IS116 IS110 IS902 family)
ANTHELSMS3_04782	COG3654	unkown
ANTHELSMS3_04784	COG3316	Transposase and inactivated derivatives
ANTHELSMS3_04788	COG3316	Transposase and inactivated derivatives
ANTHELSMS3_04789	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
ANTHELSMS3_04795	COG1172	Belongs to the binding-protein-dependent transport system permease family
ANTHELSMS3_04796	COG1129	ABC transporter
ANTHELSMS3_04799	COG4948	Mandelate Racemase Muconate Lactonizing
ANTHELSMS3_04800	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_04801	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_04806	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ANTHELSMS3_04807	COG2267	carboxylic ester hydrolase activity
ANTHELSMS3_04810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ANTHELSMS3_04811	COG2186	Transcriptional regulator
ANTHELSMS3_04814	COG3316	Transposase and inactivated derivatives
ANTHELSMS3_04823	COG1215	transferase activity, transferring glycosyl groups
ANTHELSMS3_04824	COG2273	Hydrolase Family 16
ANTHELSMS3_04825	COG1215	transferase activity, transferring glycosyl groups
ANTHELSMS3_04841	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
ANTHELSMS3_04844	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_04847	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
ANTHELSMS3_04849	COG3547	Transposase (IS116 IS110 IS902 family)
ANTHELSMS3_04851	COG0747	negative chemotaxis
ANTHELSMS3_04852	COG0601	transmembrane transport
ANTHELSMS3_04854	COG0444	Belongs to the ABC transporter superfamily
ANTHELSMS3_04855	COG4608	Belongs to the ABC transporter superfamily
ANTHELSMS3_04856	COG1396	sequence-specific DNA binding
ANTHELSMS3_04857	COG0726	polysaccharide deacetylase
ANTHELSMS3_04859	COG0765	amino acid transport
ANTHELSMS3_04860	COG0765	amino acid transport
ANTHELSMS3_04863	COG1177	transmembrane transport
ANTHELSMS3_04864	COG1176	ABC-type spermidine putrescine transport system, permease component I
ANTHELSMS3_04865	COG3842	ATPase activity
ANTHELSMS3_04869	COG3433	isochorismatase activity
ANTHELSMS3_04869	COG1535	isochorismatase
ANTHELSMS3_04870	COG2801	Transposase and inactivated derivatives
ANTHELSMS3_04882	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_04883	COG2205	protein histidine kinase activity
ANTHELSMS3_04888	COG1215	transferase activity, transferring glycosyl groups
ANTHELSMS3_04889	COG1215	transferase activity, transferring glycosyl groups
ANTHELSMS3_04890	COG3307	-O-antigen
ANTHELSMS3_04892	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
ANTHELSMS3_04896	COG2801	Transposase and inactivated derivatives
ANTHELSMS3_04899	COG0006	proline dipeptidase activity
ANTHELSMS3_04900	COG4608	Belongs to the ABC transporter superfamily
ANTHELSMS3_04901	COG0444	Belongs to the ABC transporter superfamily
ANTHELSMS3_04902	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ANTHELSMS3_04903	COG0601	transmembrane transport
ANTHELSMS3_04904	COG4166	transmembrane transport
ANTHELSMS3_04906	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANTHELSMS3_04908	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ANTHELSMS3_04909	COG1902	pentaerythritol trinitrate reductase activity
ANTHELSMS3_04912	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_04913	COG1250	3-hydroxyacyl-CoA dehydrogenase
ANTHELSMS3_04916	COG1414	Transcriptional regulator
ANTHELSMS3_04918	COG1175	transmembrane transport
ANTHELSMS3_04919	COG0395	ABC-type sugar transport system, permease component
ANTHELSMS3_04920	COG3842	ATPase activity
ANTHELSMS3_04921	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
ANTHELSMS3_04922	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
ANTHELSMS3_04924	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_04927	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
ANTHELSMS3_04932	COG2801	Transposase and inactivated derivatives
ANTHELSMS3_04934	COG2801	Transposase and inactivated derivatives
ANTHELSMS3_04940	COG2963	transposase activity
ANTHELSMS3_04942	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
ANTHELSMS3_04943	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
ANTHELSMS3_04948	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_04952	COG1609	Transcriptional regulator
ANTHELSMS3_04954	COG1175	transmembrane transport
ANTHELSMS3_04955	COG3833	ABC-type maltose transport systems, permease component
ANTHELSMS3_04957	COG0584	glycerophosphoryl diester phosphodiesterase
ANTHELSMS3_04958	COG1609	Transcriptional regulator
ANTHELSMS3_04959	COG0483	inositol monophosphate 1-phosphatase activity
ANTHELSMS3_04960	COG1053	succinate dehydrogenase
ANTHELSMS3_04964	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
ANTHELSMS3_04965	COG0673	inositol 2-dehydrogenase activity
ANTHELSMS3_04968	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_04969	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ANTHELSMS3_04972	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ANTHELSMS3_04974	COG0028	Belongs to the TPP enzyme family
ANTHELSMS3_04978	COG1012	belongs to the aldehyde dehydrogenase family
ANTHELSMS3_04979	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_04983	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
ANTHELSMS3_04985	COG1192	Involved in chromosome partitioning
ANTHELSMS3_04988	COG3609	addiction module antidote protein, CC2985 family
ANTHELSMS3_04999	COG2132	Multicopper oxidase
ANTHELSMS3_05000	COG1321	iron dependent repressor
ANTHELSMS3_05007	COG3034	peptidoglycan biosynthetic process
ANTHELSMS3_05008	COG0815	Transfers the fatty acyl group on membrane lipoproteins
ANTHELSMS3_05009	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
ANTHELSMS3_05013	COG1999	signal sequence binding
ANTHELSMS3_05015	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ANTHELSMS3_05015	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ANTHELSMS3_05017	COG1999	signal sequence binding
ANTHELSMS3_05018	COG0789	Transcriptional regulator
ANTHELSMS3_05022	COG1230	cation diffusion facilitator family transporter
ANTHELSMS3_05029	COG0398	Pfam SNARE associated Golgi protein
ANTHELSMS3_05033	COG0745	RESPONSE REGULATOR receiver
ANTHELSMS3_05034	COG2205	protein histidine kinase activity
ANTHELSMS3_05036	COG1138	Cytochrome C-type biogenesis protein
ANTHELSMS3_05037	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ANTHELSMS3_05038	COG3088	subunit of a heme lyase
ANTHELSMS3_05039	COG4235	cytochrome complex assembly
ANTHELSMS3_05052	COG2010	Cytochrome c
ANTHELSMS3_05053	COG2132	Multicopper oxidase
ANTHELSMS3_05055	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
ANTHELSMS3_05055	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
ANTHELSMS3_05068	COG2801	Transposase and inactivated derivatives
ANTHELSMS3_05083	COG1595	DNA-templated transcription, initiation
ANTHELSMS3_05092	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ANTHELSMS3_05095	COG3177	Filamentation induced by cAMP protein fic
ANTHELSMS3_05099	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
ANTHELSMS3_05099	COG0045	succinate-CoA ligase (ADP-forming) activity
ANTHELSMS3_05099	COG1042	CoA-binding domain protein
ANTHELSMS3_05102	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_05108	COG1802	Transcriptional regulator
ANTHELSMS3_05109	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ANTHELSMS3_05111	COG0028	Belongs to the TPP enzyme family
ANTHELSMS3_05114	COG1012	belongs to the aldehyde dehydrogenase family
ANTHELSMS3_05115	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
ANTHELSMS3_05116	COG2423	ornithine cyclodeaminase activity
ANTHELSMS3_05117	COG1126	abc transporter atp-binding protein
ANTHELSMS3_05119	COG2267	carboxylic ester hydrolase activity
ANTHELSMS3_05121	COG0154	amidase activity
ANTHELSMS3_05128	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_05129	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
ANTHELSMS3_05131	COG0411	ABC transporter
ANTHELSMS3_05135	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ANTHELSMS3_05138	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_05139	COG1028	Short-chain dehydrogenase reductase Sdr
ANTHELSMS3_05142	COG1960	acyl-CoA dehydrogenase activity
ANTHELSMS3_05143	COG1804	L-carnitine dehydratase bile acid-inducible protein F
ANTHELSMS3_05144	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
ANTHELSMS3_05145	COG2301	Belongs to the HpcH HpaI aldolase family
ANTHELSMS3_05154	COG0625	glutathione transferase activity
ANTHELSMS3_05155	COG0625	glutathione transferase activity
ANTHELSMS3_05156	COG0346	lactoylglutathione lyase activity
ANTHELSMS3_05158	COG0583	DNA-binding transcription factor activity
ANTHELSMS3_05162	COG2801	Transposase and inactivated derivatives