locus-tag	class	description
G8C43_00015	COG0471	metal ion transport
G8C43_00020	COG4717	serine-type aminopeptidase activity
G8C43_00030	COG2326	polyphosphate kinase activity
G8C43_00035	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
G8C43_00040	COG1702	phosphate starvation-inducible protein PhoH
G8C43_00045	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
G8C43_00060	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
G8C43_00070	COG4152	abc transporter atp-binding protein
G8C43_00085	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
G8C43_00090	COG0519	Catalyzes the synthesis of GMP from XMP
G8C43_00100	COG0735	belongs to the Fur family
G8C43_00105	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G8C43_00110	COG0516	GMP reductase activity
G8C43_00110	COG0517	IMP dehydrogenase activity
G8C43_00120	COG2814	Major facilitator Superfamily
G8C43_00125	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G8C43_00130	COG0355	proton-transporting ATP synthase activity, rotational mechanism
G8C43_00135	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
G8C43_00140	COG0196	riboflavin kinase activity
G8C43_00150	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G8C43_00165	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G8C43_00180	COG1104	cysteine desulfurase activity
G8C43_00185	COG1301	dicarboxylic acid transport
G8C43_00190	COG1234	tRNA 3'-trailer cleavage
G8C43_00195	COG2252	PERMEase
G8C43_00200	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
G8C43_00205	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
G8C43_00210	COG2824	Alkylphosphonate utilization operon protein PhnA
G8C43_00220	COG2910	NAD(P)H-binding
G8C43_00230	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G8C43_00235	COG0698	ribose 5-phosphate isomerase
G8C43_00240	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
G8C43_00250	COG2081	HI0933 family
G8C43_00270	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G8C43_00275	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G8C43_00285	COG1215	transferase activity, transferring glycosyl groups
G8C43_00295	COG1442	glycosyl transferase family 8
G8C43_00295	COG1216	Glycosyl transferase, family 2
G8C43_00335	COG0251	oxidation-reduction process
G8C43_00350	COG0860	N-Acetylmuramoyl-L-alanine amidase
G8C43_00355	COG1216	Glycosyl transferase, family 2
G8C43_00355	COG0463	Glycosyl transferase, family 2
G8C43_00360	COG0367	asparagine synthase
G8C43_00370	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
G8C43_00380	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
G8C43_00390	COG3275	phosphorelay sensor kinase activity
G8C43_00395	COG3279	Response regulator of the LytR AlgR family
G8C43_00430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G8C43_00435	COG1408	metallophosphoesterase
G8C43_00445	COG0051	transcription antitermination factor activity, RNA binding
G8C43_00450	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
G8C43_00455	COG0049	tRNA binding
G8C43_00460	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
G8C43_00470	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
G8C43_00480	COG0438	transferase activity, transferring glycosyl groups
G8C43_00485	COG0460	homoserine dehydrogenase
G8C43_00490	COG0626	cystathionine gamma-synthase activity
G8C43_00495	COG0789	Transcriptional regulator
G8C43_00500	COG1028	Short-chain dehydrogenase reductase Sdr
G8C43_00505	COG0495	leucyl-tRNA aminoacylation
G8C43_00580	COG0556	nucleotide-excision repair
G8C43_00590	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
G8C43_00595	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G8C43_00610	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G8C43_00610	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G8C43_00620	COG1272	protein, Hemolysin III
G8C43_00625	COG0237	dephospho-CoA kinase activity
G8C43_00630	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
G8C43_00630	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G8C43_00645	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
G8C43_00660	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
G8C43_00670	COG1959	2 iron, 2 sulfur cluster binding
G8C43_00690	COG0243	molybdopterin cofactor binding
G8C43_00695	COG0437	4 iron, 4 sulfur cluster binding
G8C43_00715	COG0303	'Molybdopterin
G8C43_00725	COG0746	molybdenum cofactor guanylyltransferase activity
G8C43_00745	COG2258	MOSC domain
G8C43_00755	COG0315	cyclic pyranopterin monophosphate synthase activity
G8C43_00755	COG0521	Mo-molybdopterin cofactor biosynthetic process
G8C43_00770	COG3842	ATPase activity
G8C43_00775	COG0322	excinuclease ABC activity
G8C43_00780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G8C43_00910	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
G8C43_00915	COG0583	DNA-binding transcription factor activity
G8C43_00920	COG0492	ferredoxin-NADP+ reductase activity
G8C43_00935	COG0697	spore germination
G8C43_00940	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
G8C43_00940	COG1605	Chorismate mutase
G8C43_00945	COG1162	GTPase activity
G8C43_00960	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G8C43_00970	COG0668	transmembrane transport
G8C43_00975	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
G8C43_00985	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G8C43_01010	COG2027	D-alanyl-D-alanine carboxypeptidase
G8C43_01025	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
G8C43_01040	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
G8C43_01045	COG0484	heat shock protein binding
G8C43_01060	COG0508	dehydrogenase complex catalyzes the overall conversion of
G8C43_01090	COG1442	glycosyl transferase family 8
G8C43_01090	COG1216	Glycosyl transferase, family 2
G8C43_01250	COG0110	maltose O-acetyltransferase activity
G8C43_01295	COG0489	protein tyrosine kinase activity
G8C43_01330	COG0477	Major facilitator Superfamily
G8C43_01350	COG0017	Asparaginyl-tRNA synthetase
G8C43_01380	COG0167	dihydroorotate dehydrogenase activity
G8C43_01395	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G8C43_01395	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
G8C43_01425	COG0544	peptidyl-prolyl cis-trans isomerase activity
G8C43_01435	COG0742	ribosomal rna small subunit methyltransferase
G8C43_01440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
G8C43_01445	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
G8C43_01450	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
G8C43_01465	COG0006	proline dipeptidase activity
G8C43_01515	COG2195	Cleaves the N-terminal amino acid of tripeptides
G8C43_01520	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
G8C43_01530	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
G8C43_01535	COG3001	Fructosamine kinase
G8C43_01540	COG0805	protein transport
G8C43_01550	COG0514	ATP-dependent DNA helicase (RecQ)
G8C43_01555	COG1428	Deoxynucleoside kinase
G8C43_01580	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
G8C43_01600	COG0463	Glycosyl transferase, family 2
G8C43_01610	COG1215	transferase activity, transferring glycosyl groups
G8C43_01635	COG2217	Heavy metal translocating P-type atpase
G8C43_01645	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
G8C43_01650	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
G8C43_01655	COG0259	pyridoxamine-phosphate oxidase activity
G8C43_01660	COG1678	Uncharacterized ACR, COG1678
G8C43_01670	COG1363	Peptidase, m42
G8C43_01680	COG1333	cytochrome c biogenesis protein
G8C43_01680	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
G8C43_01690	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
G8C43_01710	COG0602	queuosine metabolic process
G8C43_01725	COG1704	LemA family
G8C43_01740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
G8C43_01760	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
G8C43_01765	COG0484	heat shock protein binding
G8C43_01775	COG0242	peptide deformylase activity
G8C43_01780	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
G8C43_01785	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
G8C43_01800	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
G8C43_01815	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G8C43_01820	COG0424	maF-like protein
G8C43_01830	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G8C43_01835	COG0116	Belongs to the methyltransferase superfamily
G8C43_01835	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
G8C43_01845	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G8C43_01850	COG0667	Aldo Keto reductase
G8C43_01875	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
G8C43_01885	COG1595	DNA-templated transcription, initiation
G8C43_01895	COG1131	(ABC) transporter
G8C43_01900	COG1605	Chorismate mutase
G8C43_01900	COG0077	Prephenate dehydratase
G8C43_01915	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
G8C43_01920	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G8C43_01920	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
G8C43_01940	COG1132	(ABC) transporter
G8C43_01950	COG1192	Involved in chromosome partitioning
G8C43_01955	COG1475	DNA binding
G8C43_01970	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
G8C43_01975	COG0681	Belongs to the peptidase S26 family
G8C43_01995	COG1204	response to ionizing radiation
G8C43_02030	COG1113	amino acid transport
G8C43_02040	COG0326	Molecular chaperone. Has ATPase activity
G8C43_02050	COG0322	excinuclease ABC activity
G8C43_02055	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
G8C43_02070	COG1022	Amp-dependent synthetase and ligase
G8C43_02125	COG0252	asparaginase activity
G8C43_02145	COG0187	DNA topoisomerase II activity
G8C43_02150	COG0149	triose-phosphate isomerase activity
G8C43_02170	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G8C43_02175	COG3830	Belongs to the UPF0237 family
G8C43_02175	COG0560	Phosphoserine phosphatase
G8C43_02180	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G8C43_02185	COG3338	carbonate dehydratase activity
G8C43_02200	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
G8C43_02205	COG0492	ferredoxin-NADP+ reductase activity
G8C43_02220	COG0335	large ribosomal subunit rRNA binding
G8C43_02225	COG0012	GTP binding
G8C43_02235	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
G8C43_02240	COG0028	Belongs to the TPP enzyme family
G8C43_02245	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
G8C43_02250	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
G8C43_02260	COG3118	belongs to the thioredoxin family
G8C43_02275	COG0463	Glycosyl transferase, family 2
G8C43_02285	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
G8C43_02295	COG1045	serine acetyltransferase
G8C43_02305	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
G8C43_02310	COG0359	binds to the 23S rRNA
G8C43_02315	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
G8C43_02320	COG0360	Binds together with S18 to 16S ribosomal RNA
G8C43_02325	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
G8C43_02340	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
G8C43_02345	COG1053	succinate dehydrogenase
G8C43_02375	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
G8C43_02380	COG1181	Belongs to the D-alanine--D-alanine ligase family
G8C43_02390	COG0564	pseudouridine synthase activity
G8C43_02395	COG2877	3-deoxy-8-phosphooctulonate synthase activity
G8C43_02400	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G8C43_02415	COG0525	valine-tRNA ligase activity
G8C43_02420	COG0577	efflux transmembrane transporter activity
G8C43_02420	COG1136	(ABC) transporter
G8C43_02425	COG1136	(ABC) transporter
G8C43_02425	COG0577	efflux transmembrane transporter activity
G8C43_02430	COG1136	(ABC) transporter
G8C43_02435	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
G8C43_02445	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
G8C43_02490	COG2890	protein-(glutamine-N5) methyltransferase activity
G8C43_02495	COG0653	protein targeting
G8C43_02510	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
G8C43_02515	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G8C43_02520	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
G8C43_02525	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G8C43_02530	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
G8C43_02530	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
G8C43_02535	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G8C43_02540	COG1078	dGTPase activity
G8C43_02545	COG2204	response regulator
G8C43_02565	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
G8C43_02570	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
G8C43_02575	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
G8C43_02585	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
G8C43_02610	COG0497	DNA recombination
G8C43_02615	COG2249	NAD(P)H dehydrogenase (quinone) activity
G8C43_02620	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G8C43_02635	COG0508	dehydrogenase complex catalyzes the overall conversion of
G8C43_02645	COG1597	lipid kinase activity
G8C43_02650	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
G8C43_02665	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G8C43_02695	COG0436	Aminotransferase
G8C43_02700	COG0812	UDP-N-acetylmuramate dehydrogenase activity
G8C43_02705	COG1663	tetraacyldisaccharide 4'-kinase activity
G8C43_02760	COG0534	Mate efflux family protein
G8C43_02765	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
G8C43_02775	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
G8C43_02785	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
G8C43_02790	COG2207	Transcriptional regulator
G8C43_02790	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
G8C43_02815	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
G8C43_02820	COG0563	adenylate kinase activity
G8C43_02830	COG0589	response to stress
G8C43_02835	COG0750	zinc metalloprotease
G8C43_02845	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G8C43_02850	COG0438	transferase activity, transferring glycosyl groups
G8C43_02880	COG1216	Glycosyl transferase, family 2
G8C43_02880	COG1442	glycosyl transferase family 8
G8C43_02885	COG1216	Glycosyl transferase, family 2
G8C43_02885	COG1442	glycosyl transferase family 8
G8C43_02895	COG2244	polysaccharide biosynthetic process
G8C43_02915	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
G8C43_02920	COG0793	Belongs to the peptidase S41A family
G8C43_02925	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
G8C43_02935	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
G8C43_02940	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
G8C43_02945	COG1120	ATPase activity
G8C43_02955	COG0277	FAD linked oxidase domain protein
G8C43_02985	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
G8C43_03000	COG2365	Tyrosine phosphatase family
G8C43_03005	COG2217	Heavy metal translocating P-type atpase
G8C43_03030	COG4771	TonB-dependent receptor
G8C43_03070	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
G8C43_03090	COG3179	chitinase
G8C43_03150	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
G8C43_03155	COG0228	four-way junction DNA binding
G8C43_03160	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
G8C43_03165	COG0825	malonyl-CoA metabolic process
G8C43_03170	COG1418	mRNA catabolic process
G8C43_03180	COG0642	Histidine kinase
G8C43_03185	COG0745	RESPONSE REGULATOR receiver
G8C43_03195	COG1566	PFAM secretion protein HlyD family protein
G8C43_03210	COG4574	serine-type endopeptidase inhibitor activity
G8C43_03220	COG0022	dehydrogenase e1 component
G8C43_03225	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
G8C43_03240	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
G8C43_03255	COG0673	inositol 2-dehydrogenase activity
G8C43_03265	COG0656	L-ascorbic acid biosynthetic process
G8C43_03275	COG4221	oxidoreductase activity
G8C43_03295	COG1611	Belongs to the LOG family
G8C43_03310	COG2885	chlorophyll binding
G8C43_03310	COG3047	cAMP biosynthetic process
G8C43_03330	COG2207	Transcriptional regulator
G8C43_03330	COG1917	Cupin 2, conserved barrel domain protein
G8C43_03335	COG2755	lipolytic protein G-D-S-L family
G8C43_03335	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G8C43_03400	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
G8C43_03440	COG4206	TonB-dependent receptor
G8C43_03450	COG1007	ATP synthesis coupled electron transport
G8C43_03465	COG1619	proteins homologs of microcin C7 resistance protein MccF
G8C43_03500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
G8C43_03500	COG0519	Catalyzes the synthesis of GMP from XMP
G8C43_03510	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G8C43_03510	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G8C43_03515	COG2195	Cleaves the N-terminal amino acid of tripeptides
G8C43_03535	COG0753	catalase activity
G8C43_03545	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
G8C43_03560	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G8C43_03570	COG1902	pentaerythritol trinitrate reductase activity
G8C43_03590	COG0138	bifunctional purine biosynthesis protein purh
G8C43_03605	COG0724	RNA recognition motif
G8C43_03615	COG0509	glycine decarboxylation via glycine cleavage system
G8C43_03625	COG0632	four-way junction helicase activity
G8C43_03645	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
G8C43_03655	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
G8C43_03660	COG0539	negative regulation of cytoplasmic translation
G8C43_03710	COG0300	oxidoreductase activity
G8C43_03715	COG0783	Belongs to the Dps family
G8C43_03740	COG0443	Heat shock 70 kDa protein
G8C43_03755	COG1126	abc transporter atp-binding protein
G8C43_03770	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
G8C43_03785	COG0463	Glycosyl transferase, family 2
G8C43_03790	COG2954	triphosphatase activity
G8C43_03800	COG1335	isochorismatase
G8C43_03805	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
G8C43_03810	COG4975	Glucose uptake
G8C43_03815	COG1028	Short-chain dehydrogenase reductase Sdr
G8C43_03820	COG2706	6-phosphogluconolactonase activity
G8C43_03825	COG0148	phosphopyruvate hydratase activity
G8C43_03845	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
G8C43_03845	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
G8C43_03865	COG1262	PFAM Formylglycine-generating sulfatase enzyme
G8C43_03880	COG0527	aspartate kinase activity
G8C43_03905	COG1733	regulation of RNA biosynthetic process
G8C43_03935	COG0606	chelatase, subunit chli
G8C43_03950	COG3118	belongs to the thioredoxin family
G8C43_03955	COG0321	lipoyl(octanoyl) transferase activity
G8C43_03965	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G8C43_03965	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
G8C43_03970	COG1739	Uncharacterized protein family UPF0029
G8C43_03975	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
G8C43_03980	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
G8C43_03990	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
G8C43_03995	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
G8C43_04000	COG1530	ribonuclease E activity
G8C43_04005	COG0776	regulation of translation
G8C43_04025	COG1253	flavin adenine dinucleotide binding
G8C43_04045	COG0546	phosphoglycolate phosphatase activity
G8C43_04050	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
G8C43_04055	COG0004	ammonium transporteR
G8C43_04065	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
G8C43_04110	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
G8C43_04120	COG0586	Pfam SNARE associated Golgi protein
G8C43_04125	COG1595	DNA-templated transcription, initiation
G8C43_04140	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G8C43_04160	COG3477	response to acidic pH
G8C43_04165	COG0124	histidyl-tRNA synthetase
G8C43_04190	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
G8C43_04200	COG0423	glycine-tRNA ligase activity
G8C43_04205	COG0828	Belongs to the bacterial ribosomal protein bS21 family
G8C43_04210	COG4974	Belongs to the 'phage' integrase family
G8C43_04215	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
G8C43_04260	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
G8C43_04265	COG0081	regulation of translation
G8C43_04270	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
G8C43_04275	COG0222	ribosome binding
G8C43_04280	COG0085	RNA polymerase activity
G8C43_04285	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
G8C43_04295	COG1629	transport
G8C43_04305	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
G8C43_04320	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
G8C43_04325	COG1522	sequence-specific DNA binding
G8C43_04340	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G8C43_04345	COG2226	methyltransferase
G8C43_04365	COG0531	amino acid
G8C43_04370	COG1012	belongs to the aldehyde dehydrogenase family
G8C43_04390	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
G8C43_04395	COG2814	Major facilitator Superfamily
G8C43_04400	COG0656	L-ascorbic acid biosynthetic process
G8C43_04415	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
G8C43_04450	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
G8C43_04455	COG2166	iron-sulfur cluster assembly
G8C43_04465	COG0508	dehydrogenase complex catalyzes the overall conversion of
G8C43_04465	COG0022	dehydrogenase e1 component
G8C43_04470	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
G8C43_04490	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
G8C43_04495	COG0772	Belongs to the SEDS family
G8C43_04505	COG1792	Involved in formation and maintenance of cell shape
G8C43_04515	COG0616	signal peptide processing
G8C43_04520	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
G8C43_04520	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
G8C43_04525	COG2885	chlorophyll binding
G8C43_04530	COG0203	ribosomal protein L17
G8C43_04535	COG0202	RNA polymerase activity
G8C43_04540	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
G8C43_04545	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
G8C43_04550	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
G8C43_04555	COG0257	Belongs to the bacterial ribosomal protein bL36 family
G8C43_04560	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
G8C43_04565	COG0201	protein transport
G8C43_04570	COG0200	Binds to the 23S rRNA
G8C43_04575	COG1841	ribosomal large subunit assembly
G8C43_04580	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
G8C43_04585	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
G8C43_04590	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
G8C43_04595	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
G8C43_04600	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
G8C43_04605	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
G8C43_04615	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
G8C43_04620	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
G8C43_04625	COG0255	Belongs to the universal ribosomal protein uL29 family
G8C43_04630	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
G8C43_04635	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
G8C43_04640	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
G8C43_04645	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
G8C43_04650	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
G8C43_04655	COG0089	rRNA binding
G8C43_04660	COG0088	Forms part of the polypeptide exit tunnel
G8C43_04665	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
G8C43_04670	COG1505	serine-type exopeptidase activity
G8C43_04675	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
G8C43_04675	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
G8C43_04690	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G8C43_04705	COG1210	Utp--glucose-1-phosphate uridylyltransferase
G8C43_04710	COG0756	dUTP diphosphatase activity
G8C43_04720	COG0433	COG0433 Predicted ATPase
G8C43_04725	COG2176	DNA-directed DNA polymerase activity
G8C43_04730	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
G8C43_04745	COG0019	diaminopimelate decarboxylase activity
G8C43_04775	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G8C43_04835	COG0745	RESPONSE REGULATOR receiver
G8C43_04840	COG5002	protein histidine kinase activity
G8C43_04845	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
G8C43_04870	COG2353	YceI-like domain
G8C43_04875	COG0646	methionine synthase
G8C43_04875	COG1410	methionine synthase
G8C43_04885	COG0586	Pfam SNARE associated Golgi protein
G8C43_04890	COG1301	dicarboxylic acid transport
G8C43_04905	COG0842	Transport permease protein
G8C43_04910	COG1131	(ABC) transporter
G8C43_04915	COG1131	(ABC) transporter
G8C43_04935	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
G8C43_04945	COG0105	UTP biosynthetic process
G8C43_04950	COG0295	cytidine deaminase activity
G8C43_04955	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
G8C43_04970	COG1024	Enoyl-CoA hydratase
G8C43_04970	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G8C43_04975	COG0183	Belongs to the thiolase family
G8C43_05010	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
G8C43_05015	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
G8C43_05025	COG0131	Imidazoleglycerol-phosphate dehydratase
G8C43_05030	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
G8C43_05035	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
G8C43_05040	COG0107	imidazoleglycerol-phosphate synthase activity
G8C43_05045	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G8C43_05045	COG0140	phosphoribosyl-ATP diphosphatase activity
G8C43_05050	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
G8C43_05055	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
G8C43_05065	COG0488	(ABC) transporter
G8C43_05070	COG0730	response to heat
G8C43_05090	COG0204	Acyl-transferase
G8C43_05095	COG1482	cell wall glycoprotein biosynthetic process
G8C43_05110	COG0598	Magnesium transport protein CorA
G8C43_05115	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
G8C43_05140	COG0463	Glycosyl transferase, family 2
G8C43_05145	COG0039	L-malate dehydrogenase activity
G8C43_05150	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
G8C43_05165	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
G8C43_05185	COG1770	oligopeptidase
G8C43_05190	COG0393	Putative heavy-metal-binding
G8C43_05205	COG0649	NAD binding
G8C43_05210	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G8C43_05215	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G8C43_05220	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G8C43_05225	COG4774	siderophore transport
G8C43_05320	COG1160	GTP binding
G8C43_05345	COG0437	4 iron, 4 sulfur cluster binding
G8C43_05355	COG0470	DNA polymerase III
G8C43_05360	COG0305	Participates in initiation and elongation during chromosome replication
G8C43_05365	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
G8C43_05370	COG0291	Belongs to the bacterial ribosomal protein bL35 family
G8C43_05380	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
G8C43_05385	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
G8C43_05390	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
G8C43_05395	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
G8C43_05400	COG2076	Multidrug Resistance protein
G8C43_05405	COG2255	four-way junction helicase activity
G8C43_05410	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G8C43_05415	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
G8C43_05420	COG0713	ATP synthesis coupled electron transport
G8C43_05430	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
G8C43_05435	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
G8C43_05440	COG1034	ATP synthesis coupled electron transport
G8C43_05500	COG0527	aspartate kinase activity
G8C43_05500	COG0460	homoserine dehydrogenase
G8C43_05505	COG0083	homoserine kinase activity
G8C43_05510	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
G8C43_05515	COG0528	UMP kinase activity
G8C43_05520	COG0233	cytoplasmic translational termination
G8C43_05525	COG0287	Prephenate dehydrogenase
G8C43_05535	COG0336	Belongs to the RNA methyltransferase TrmD family
G8C43_05555	COG1522	sequence-specific DNA binding
G8C43_05560	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
G8C43_05570	COG0306	phosphate transporter
G8C43_05580	COG0358	DNA primase activity
G8C43_05595	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
G8C43_05625	COG0488	(ABC) transporter
G8C43_05635	COG2217	Heavy metal translocating P-type atpase
G8C43_05655	COG0348	domain, Protein
G8C43_05670	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
G8C43_05690	COG1774	PSP1 C-terminal conserved region
G8C43_05730	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
G8C43_05740	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
G8C43_05750	COG3842	ATPase activity
G8C43_05760	COG1970	mechanosensitive ion channel activity
G8C43_05775	COG0442	prolyl-tRNA aminoacylation
G8C43_05780	COG1519	Transferase
G8C43_05780	COG0220	tRNA (guanine-N7-)-methyltransferase activity
G8C43_05785	COG1385	rRNA (uridine-N3-)-methyltransferase activity
G8C43_05790	COG2151	metal-sulfur cluster biosynthetic enzyme
G8C43_05800	COG0594	ribonuclease P activity
G8C43_05820	COG2304	oxidoreductase activity
G8C43_05825	COG2304	oxidoreductase activity
G8C43_05840	COG0714	Associated with various cellular activities
G8C43_05845	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
G8C43_05855	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
G8C43_05865	COG0826	peptidase U32
G8C43_05870	COG1028	Short-chain dehydrogenase reductase Sdr
G8C43_05875	COG1878	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation
G8C43_05880	COG0635	Involved in the biosynthesis of porphyrin-containing compound
G8C43_05895	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G8C43_05905	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G8C43_05925	COG2814	Major facilitator Superfamily
G8C43_05935	COG1028	Short-chain dehydrogenase reductase Sdr
G8C43_05945	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
G8C43_05980	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
G8C43_05995	COG0045	succinate-CoA ligase (ADP-forming) activity
G8C43_06015	COG0823	Involved in the tonB-independent uptake of proteins
G8C43_06015	COG1506	peptidase
G8C43_06020	COG0588	phosphoglycerate mutase activity
G8C43_06035	COG0268	Binds directly to 16S ribosomal RNA
G8C43_06050	COG0285	dihydrofolate synthase activity
G8C43_06060	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
G8C43_06065	COG0612	Peptidase, M16
G8C43_06070	COG0009	L-threonylcarbamoyladenylate synthase
G8C43_06075	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
G8C43_06080	COG0628	permease
G8C43_06085	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
G8C43_06105	COG0778	Nitroreductase
G8C43_06110	COG1846	Transcriptional regulator
G8C43_06120	COG2011	ABC-type metal ion transport system permease component
G8C43_06125	COG1464	Belongs to the NlpA lipoprotein family
G8C43_06130	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
G8C43_06145	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
G8C43_06150	COG1132	(ABC) transporter
G8C43_06160	COG0791	NLP P60 protein
G8C43_06175	COG2333	competence protein COMEC
G8C43_06175	COG0658	competence protein
G8C43_06190	COG0668	transmembrane transport
G8C43_06200	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
G8C43_06205	COG0857	belongs to the CobB CobQ family
G8C43_06205	COG0280	phosphate acetyltransferase
G8C43_06210	COG0321	lipoyl(octanoyl) transferase activity
G8C43_06210	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
G8C43_06225	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
G8C43_06235	COG2515	1-aminocyclopropane-1-carboxylate deaminase
G8C43_06240	COG3104	oligopeptide transport
G8C43_06245	COG3104	oligopeptide transport
G8C43_06280	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
G8C43_06295	COG3586	endonuclease activity
G8C43_06315	COG3023	N-Acetylmuramoyl-L-alanine amidase
G8C43_06320	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
G8C43_06345	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
G8C43_06350	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
G8C43_06350	COG0284	orotidine-5'-phosphate decarboxylase activity
G8C43_06360	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
G8C43_06360	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
G8C43_06365	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
G8C43_06370	COG0602	queuosine metabolic process
G8C43_06375	COG0450	alkyl hydroperoxide reductase
G8C43_06390	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
G8C43_06395	COG0113	porphobilinogen synthase activity
G8C43_06410	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
G8C43_06415	COG0217	transcriptional regulatory protein
G8C43_06425	COG1472	Belongs to the glycosyl hydrolase 3 family
G8C43_06435	COG0737	Belongs to the 5'-nucleotidase family
G8C43_06450	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
G8C43_06455	COG0463	Glycosyl transferase, family 2
G8C43_06460	COG1216	Glycosyl transferase, family 2
G8C43_06480	COG1216	Glycosyl transferase, family 2
G8C43_06480	COG0463	Glycosyl transferase, family 2
G8C43_06525	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
G8C43_06540	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
G8C43_06545	COG0436	Aminotransferase
G8C43_06555	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G8C43_06565	COG2732	(Barnase) inhibitor
G8C43_06570	COG0463	Glycosyl transferase, family 2
G8C43_06585	COG1506	peptidase
G8C43_06585	COG0823	Involved in the tonB-independent uptake of proteins
G8C43_06605	COG1380	Effector of murein hydrolase LrgA
G8C43_06610	COG1346	cytolysis
G8C43_06615	COG0557	exoribonuclease II activity
G8C43_06620	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
G8C43_06620	COG2169	Transcriptional regulator
G8C43_06625	COG0159	tryptophan synthase activity
G8C43_06630	COG0135	phosphoribosylanthranilate isomerase activity
G8C43_06635	COG0134	indole-3-glycerol-phosphate synthase activity
G8C43_06645	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
G8C43_06650	COG0512	Glutamine amidotransferase of anthranilate synthase
G8C43_06655	COG1335	isochorismatase
G8C43_06660	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
G8C43_06665	COG0133	tryptophan synthase activity
G8C43_06670	COG3047	cAMP biosynthetic process
G8C43_06670	COG2885	chlorophyll binding
G8C43_06680	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
G8C43_06680	COG0140	phosphoribosyl-ATP diphosphatase activity
G8C43_06685	COG0811	peptide transport
G8C43_06690	COG0848	biopolymer transport protein
G8C43_06700	COG0719	Fe-S assembly protein
G8C43_06710	COG0316	Belongs to the HesB IscA family
G8C43_06715	COG2267	carboxylic ester hydrolase activity
G8C43_06730	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
G8C43_06740	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
G8C43_06745	COG0181	hydroxymethylbilane synthase activity
G8C43_06750	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G8C43_06760	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
G8C43_06780	COG1132	(ABC) transporter
G8C43_06785	COG0101	tRNA pseudouridine synthase activity
G8C43_06805	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
G8C43_06810	COG0460	homoserine dehydrogenase
G8C43_06810	COG0527	aspartate kinase activity
G8C43_06820	COG0126	phosphoglycerate kinase activity
G8C43_06830	COG0445	tRNA wobble uridine modification
G8C43_06835	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
G8C43_06840	COG1752	Esterase of the alpha-beta hydrolase superfamily
G8C43_06855	COG0438	transferase activity, transferring glycosyl groups
G8C43_06860	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
G8C43_06865	COG0438	transferase activity, transferring glycosyl groups
G8C43_06870	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
G8C43_06875	COG0438	transferase activity, transferring glycosyl groups
G8C43_06930	COG2814	Major facilitator Superfamily
G8C43_06930	COG0477	Major facilitator Superfamily
G8C43_06945	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
G8C43_06945	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
G8C43_06955	COG0667	Aldo Keto reductase
G8C43_06960	COG0300	oxidoreductase activity
G8C43_06980	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
G8C43_06995	COG0584	glycerophosphoryl diester phosphodiesterase
G8C43_07000	COG2271	Major facilitator Superfamily
G8C43_07005	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G8C43_07010	COG1349	DNA-binding transcription factor activity
G8C43_07015	COG0247	lactate metabolic process
G8C43_07025	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
G8C43_07030	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
G8C43_07035	COG1113	amino acid transport
G8C43_07040	COG0596	Alpha beta hydrolase
G8C43_07045	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
G8C43_07055	COG1214	PFAM Peptidase M22, glycoprotease
G8C43_07110	COG4221	oxidoreductase activity
G8C43_07115	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
G8C43_07120	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
G8C43_07130	COG1187	pseudouridine synthase activity
G8C43_07150	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
G8C43_07165	COG3022	response to hydroperoxide
G8C43_07170	COG0719	Fe-S assembly protein
G8C43_07175	COG0396	ATPase activity
G8C43_07195	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
G8C43_07200	COG1435	thymidine kinase activity
G8C43_07210	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
G8C43_07215	COG1959	2 iron, 2 sulfur cluster binding
G8C43_07225	COG0210	DNA helicase
G8C43_07245	COG1073	alpha beta
G8C43_07260	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
G8C43_07275	COG0791	NLP P60 protein
G8C43_07280	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
G8C43_07285	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
G8C43_07290	COG0277	FAD linked oxidase domain protein
G8C43_07325	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
G8C43_07330	COG0095	Lipoate-protein ligase
G8C43_07335	COG1575	Belongs to the MenA family. Type 1 subfamily
G8C43_07345	COG0328	RNA-DNA hybrid ribonuclease activity
G8C43_07350	COG0791	NLP P60 protein
G8C43_07355	COG0488	(ABC) transporter
G8C43_07360	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
G8C43_07375	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
G8C43_07380	COG1454	alcohol dehydrogenase
G8C43_07400	COG0471	metal ion transport
G8C43_07405	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
G8C43_07410	COG2204	response regulator
G8C43_07430	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
G8C43_07445	COG0482	sulfurtransferase activity
G8C43_07450	COG1381	Involved in DNA repair and RecF pathway recombination
G8C43_07460	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
G8C43_07465	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
G8C43_07470	COG0052	Belongs to the universal ribosomal protein uS2 family
G8C43_07475	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
G8C43_07485	COG1914	H( )-stimulated, divalent metal cation uptake system
G8C43_07500	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
G8C43_07505	COG0191	fructose-bisphosphate aldolase activity
G8C43_07520	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
G8C43_07530	COG0179	Fumarylacetoacetate (FAA) hydrolase
G8C43_07535	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
G8C43_07540	COG1183	phosphatidylcholine synthase activity
G8C43_07550	COG0779	Required for maturation of 30S ribosomal subunits
G8C43_07555	COG0195	Participates in both transcription termination and antitermination
G8C43_07560	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
G8C43_07565	COG4206	TonB-dependent receptor
G8C43_07565	COG1629	transport
G8C43_07570	COG0702	epimerase
G8C43_07590	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
G8C43_07595	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
G8C43_07605	COG0067	glutamate synthase
G8C43_07605	COG0069	glutamate synthase activity
G8C43_07605	COG0070	glutamate synthase
G8C43_07615	COG0697	spore germination
G8C43_07625	COG0820	rRNA (adenine-C2-)-methyltransferase activity
G8C43_07630	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
G8C43_07640	COG0194	GDP metabolic process
G8C43_07645	COG1561	YicC-like family, N-terminal region
G8C43_07655	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
G8C43_07665	COG2226	methyltransferase
G8C43_07685	COG1418	mRNA catabolic process
G8C43_07690	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
G8C43_07695	COG0307	riboflavin synthase, alpha
G8C43_07705	COG0542	response to heat
G8C43_07740	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G8C43_07745	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
G8C43_07760	COG0720	synthase
G8C43_07770	COG1607	acyl-coa hydrolase
G8C43_07785	COG0481	GTPase activity
G8C43_07790	COG2855	membrane
G8C43_07795	COG0288	reversible hydration of carbon dioxide
G8C43_07805	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
G8C43_07815	COG0540	Belongs to the ATCase OTCase family
G8C43_07830	COG1368	sulfuric ester hydrolase activity
G8C43_07840	COG0561	phosphatase activity
G8C43_07845	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
G8C43_07850	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
G8C43_07855	COG0571	ribonuclease III activity
G8C43_07865	COG0469	pyruvate kinase activity
G8C43_07880	COG1819	glycosyl
G8C43_07885	COG0596	Alpha beta hydrolase
G8C43_07895	COG3321	synthase
G8C43_07895	COG0604	alcohol dehydrogenase
G8C43_07900	COG3321	synthase
G8C43_07900	COG0604	alcohol dehydrogenase
G8C43_07905	COG0534	Mate efflux family protein
G8C43_07920	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G8C43_07950	COG0357	Ribosomal RNA small subunit methyltransferase G
G8C43_07955	COG2183	response to ionizing radiation
G8C43_07965	COG1610	YqeY-like protein
G8C43_07970	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
G8C43_07985	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
G8C43_07990	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
G8C43_07995	COG0772	Belongs to the SEDS family
G8C43_08000	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
G8C43_08005	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
G8C43_08010	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
G8C43_08025	COG0275	rRNA processing
G8C43_08030	COG2001	Belongs to the MraZ family
G8C43_08035	COG2267	carboxylic ester hydrolase activity
G8C43_08040	COG0218	Necessary for normal cell division and for the maintenance of normal septation
G8C43_08045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G8C43_08065	COG1185	polyribonucleotide nucleotidyltransferase activity
G8C43_08070	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
G8C43_08085	COG3590	peptidase
G8C43_08090	COG2884	Cell division ATP-binding protein ftsE
G8C43_08115	COG0564	pseudouridine synthase activity
G8C43_08120	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
G8C43_08125	COG1968	undecaprenyl-diphosphatase activity
G8C43_08135	COG2177	Part of the ABC transporter FtsEX involved in
G8C43_08140	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
G8C43_08150	COG1271	oxidase subunit
G8C43_08160	COG1074	ATP-dependent DNA helicase activity
G8C43_08170	COG0792	nuclease activity
G8C43_08175	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
G8C43_08180	COG5000	phosphorelay sensor kinase activity
G8C43_08190	COG1132	(ABC) transporter
G8C43_08205	COG0583	DNA-binding transcription factor activity
G8C43_08210	COG2855	membrane
G8C43_08215	COG0165	Argininosuccinate lyase
G8C43_08220	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
G8C43_08225	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
G8C43_08230	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
G8C43_08240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
G8C43_08245	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
G8C43_08250	COG0137	argininosuccinate synthase activity
G8C43_08270	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G8C43_08270	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
G8C43_08285	COG1674	ftsk spoiiie
G8C43_08290	COG0670	Belongs to the BI1 family
G8C43_08295	COG0698	ribose 5-phosphate isomerase
G8C43_08300	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
G8C43_08310	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
G8C43_08315	COG0440	acetolactate synthase activity
G8C43_08325	COG0028	Belongs to the TPP enzyme family
G8C43_08335	COG0473	3-isopropylmalate dehydrogenase activity
G8C43_08340	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G8C43_08345	COG0066	3-isopropylmalate dehydratase activity
G8C43_08350	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
G8C43_08355	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
G8C43_08360	COG1119	ATPase activity
G8C43_08375	COG0084	hydrolase, TatD family'
G8C43_08380	COG3594	Acyltransferase
G8C43_08385	COG0211	Belongs to the bacterial ribosomal protein bL27 family
G8C43_08390	COG0261	This protein binds to 23S rRNA in the presence of protein L20
G8C43_08395	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
G8C43_08400	COG0561	phosphatase activity
G8C43_08415	COG0247	lactate metabolic process
G8C43_08415	COG2181	nitrate reductase activity
G8C43_08420	COG0247	lactate metabolic process
G8C43_08420	COG2181	nitrate reductase activity
G8C43_08460	COG2239	Acts as a magnesium transporter
G8C43_08480	COG0815	Transfers the fatty acyl group on membrane lipoproteins
G8C43_08485	COG0227	Belongs to the bacterial ribosomal protein bL28 family
G8C43_08490	COG0267	Belongs to the bacterial ribosomal protein bL33 family
G8C43_08500	COG0552	protein localization to endoplasmic reticulum
G8C43_08510	COG0242	peptide deformylase activity
G8C43_08515	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
G8C43_08565	COG1393	Belongs to the ArsC family
G8C43_08575	COG0180	Tryptophanyl-tRNA synthetase
G8C43_08580	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
G8C43_08590	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
G8C43_08595	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
G8C43_08600	COG0561	phosphatase activity
G8C43_08605	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
G8C43_08690	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
G8C43_08700	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
G8C43_08720	COG2356	endonuclease I
G8C43_08740	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
G8C43_08750	COG0463	Glycosyl transferase, family 2
G8C43_08755	COG0193	aminoacyl-tRNA hydrolase activity
G8C43_08760	COG0726	polysaccharide deacetylase
G8C43_08765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
G8C43_08790	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
G8C43_08810	COG3158	transport of potassium into the cell
G8C43_08815	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
G8C43_08820	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
G8C43_08825	COG1022	Amp-dependent synthetase and ligase
G8C43_08835	COG1136	(ABC) transporter
G8C43_08845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
G8C43_08865	COG2217	Heavy metal translocating P-type atpase
G8C43_08870	COG0513	Belongs to the DEAD box helicase family
G8C43_08880	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
G8C43_08885	COG1027	Aspartate ammonia-lyase
G8C43_08890	COG2985	domain, Protein
G8C43_08900	COG0252	asparaginase activity
G8C43_08915	COG4948	Mandelate Racemase Muconate Lactonizing
G8C43_08925	COG1556	Lactate utilization protein
G8C43_08930	COG1139	Iron-sulfur cluster binding protein
G8C43_08935	COG0247	lactate metabolic process
G8C43_08940	COG0037	tRNA processing
G8C43_08945	COG1295	ribonuclease BN
G8C43_08960	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
G8C43_08965	COG0339	signal peptide processing
G8C43_08980	COG2003	Belongs to the UPF0758 family
G8C43_09005	COG0542	response to heat
G8C43_09080	COG2137	regulation of response to DNA damage stimulus
G8C43_09085	COG3118	belongs to the thioredoxin family
G8C43_09100	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
G8C43_09115	COG0156	8-amino-7-oxononanoate synthase activity
G8C43_09120	COG1490	D-aminoacyl-tRNA deacylase activity
G8C43_09125	COG2885	chlorophyll binding
G8C43_09130	COG0708	Exodeoxyribonuclease III
G8C43_09150	COG0641	radical SAM
G8C43_09165	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
G8C43_09170	COG1028	Short-chain dehydrogenase reductase Sdr
G8C43_09200	COG0667	Aldo Keto reductase
G8C43_09205	COG1058	Belongs to the CinA family
G8C43_09205	COG1546	Belongs to the CinA family
G8C43_09210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
G8C43_09220	COG1227	inorganic diphosphatase activity
G8C43_09225	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
G8C43_09235	COG2096	Adenosyltransferase
G8C43_09245	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
G8C43_09255	COG3852	Histidine kinase
G8C43_09260	COG1137	ATPase activity
G8C43_09275	COG1252	NADH dehydrogenase
G8C43_09285	COG0739	heme binding
G8C43_09290	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
G8C43_09330	COG1649	PFAM Uncharacterised BCR, COG1649
G8C43_09335	COG1086	Polysaccharide biosynthesis protein
G8C43_09340	COG0018	arginyl-trna synthetase
G8C43_09350	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
G8C43_09375	COG3425	synthase
G8C43_09380	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
G8C43_09385	COG0813	purine-nucleoside phosphorylase activity
G8C43_09390	COG2234	aminopeptidase activity
G8C43_09400	COG0739	heme binding
G8C43_09410	COG2759	Belongs to the formate--tetrahydrofolate ligase family
G8C43_09415	COG0232	Belongs to the dGTPase family. Type 2 subfamily
G8C43_09420	COG1193	negative regulation of DNA recombination
G8C43_09425	COG3011	Protein conserved in bacteria
G8C43_09445	COG0799	negative regulation of ribosome biogenesis
G8C43_09450	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
G8C43_09460	COG4589	Belongs to the CDS family
G8C43_09465	COG0688	phosphatidylethanolamine metabolic process
G8C43_09470	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
G8C43_09510	COG0542	response to heat
G8C43_09515	COG0738	Major facilitator superfamily
G8C43_09525	COG0531	amino acid
G8C43_09545	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
G8C43_09555	COG0254	rRNA binding
G8C43_09560	COG0538	isocitrate dehydrogenase activity
G8C43_09565	COG0318	PFAM AMP-dependent synthetase and ligase
G8C43_09600	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
G8C43_09605	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
G8C43_09615	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
G8C43_09620	COG0297	glycogen (starch) synthase activity
G8C43_09630	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
G8C43_09635	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
G8C43_09650	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
G8C43_09655	COG1349	DNA-binding transcription factor activity
G8C43_09660	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
G8C43_09665	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
G8C43_09670	COG0371	Dehydrogenase
G8C43_09690	COG1069	ribulokinase activity
G8C43_09695	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
G8C43_09725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
G8C43_09735	COG0215	cysteine-tRNA ligase activity
G8C43_09740	COG0302	gtp cyclohydrolase
G8C43_09750	COG3339	Conserved Protein
G8C43_09755	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
G8C43_09760	COG1979	alcohol dehydrogenase
G8C43_09765	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
G8C43_09770	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
G8C43_09775	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G8C43_09780	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
G8C43_09785	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
G8C43_09790	COG0356	it plays a direct role in the translocation of protons across the membrane
G8C43_09805	COG0333	Belongs to the bacterial ribosomal protein bL32 family
G8C43_09810	COG0511	ligase activity, forming carbon-carbon bonds
G8C43_09815	COG0439	Biotin carboxylase
G8C43_09825	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
G8C43_09825	COG0617	tRNA 3'-terminal CCA addition
G8C43_09825	COG0517	IMP dehydrogenase activity
G8C43_09835	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
G8C43_09840	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
G8C43_09845	COG0671	phosphoesterase, PA-phosphatase related
G8C43_09850	COG2211	Major facilitator Superfamily
G8C43_09865	COG0504	CTP synthase activity
G8C43_09870	COG0706	membrane insertase activity
G8C43_09880	COG0205	6-phosphofructokinase activity
G8C43_09885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
G8C43_09890	COG0230	Belongs to the bacterial ribosomal protein bL34 family