locus-tag	class	description
GYM73_00020	COG4221	oxidoreductase activity
GYM73_00025	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GYM73_00030	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GYM73_00040	COG1187	pseudouridine synthase activity
GYM73_00060	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GYM73_00075	COG3022	response to hydroperoxide
GYM73_00080	COG0719	Fe-S assembly protein
GYM73_00085	COG0396	ATPase activity
GYM73_00105	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GYM73_00110	COG1435	thymidine kinase activity
GYM73_00120	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GYM73_00125	COG1959	2 iron, 2 sulfur cluster binding
GYM73_00140	COG1073	alpha beta
GYM73_00155	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GYM73_00170	COG0791	NLP P60 protein
GYM73_00175	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GYM73_00180	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
GYM73_00185	COG0277	FAD linked oxidase domain protein
GYM73_00215	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GYM73_00220	COG0095	Lipoate-protein ligase
GYM73_00225	COG1575	Belongs to the MenA family. Type 1 subfamily
GYM73_00240	COG0791	NLP P60 protein
GYM73_00245	COG0488	(ABC) transporter
GYM73_00250	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GYM73_00265	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GYM73_00270	COG1454	alcohol dehydrogenase
GYM73_00290	COG0471	metal ion transport
GYM73_00295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GYM73_00300	COG2204	response regulator
GYM73_00320	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GYM73_00335	COG0482	sulfurtransferase activity
GYM73_00340	COG1381	Involved in DNA repair and RecF pathway recombination
GYM73_00355	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GYM73_00360	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GYM73_00365	COG0052	Belongs to the universal ribosomal protein uS2 family
GYM73_00370	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GYM73_00380	COG1914	H( )-stimulated, divalent metal cation uptake system
GYM73_00395	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GYM73_00400	COG0191	fructose-bisphosphate aldolase activity
GYM73_00410	COG1902	pentaerythritol trinitrate reductase activity
GYM73_00415	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
GYM73_00425	COG0179	Fumarylacetoacetate (FAA) hydrolase
GYM73_00430	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GYM73_00435	COG1183	phosphatidylcholine synthase activity
GYM73_00445	COG0779	Required for maturation of 30S ribosomal subunits
GYM73_00450	COG0195	Participates in both transcription termination and antitermination
GYM73_00455	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GYM73_00460	COG1629	transport
GYM73_00460	COG4206	TonB-dependent receptor
GYM73_00465	COG0702	epimerase
GYM73_00485	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GYM73_00490	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GYM73_00500	COG0067	glutamate synthase
GYM73_00500	COG0069	glutamate synthase activity
GYM73_00500	COG0070	glutamate synthase
GYM73_00510	COG0697	spore germination
GYM73_00520	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GYM73_00525	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GYM73_00535	COG0194	GDP metabolic process
GYM73_00540	COG1561	YicC-like family, N-terminal region
GYM73_00550	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GYM73_00560	COG2226	methyltransferase
GYM73_00580	COG1418	mRNA catabolic process
GYM73_00585	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GYM73_00590	COG0307	riboflavin synthase, alpha
GYM73_00600	COG0542	response to heat
GYM73_00635	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GYM73_00640	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GYM73_00655	COG0720	synthase
GYM73_00665	COG1607	acyl-coa hydrolase
GYM73_00680	COG0481	GTPase activity
GYM73_00685	COG2855	membrane
GYM73_00690	COG0288	reversible hydration of carbon dioxide
GYM73_00700	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
GYM73_00710	COG0540	Belongs to the ATCase OTCase family
GYM73_00725	COG1368	sulfuric ester hydrolase activity
GYM73_00740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GYM73_00745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GYM73_00750	COG0571	ribonuclease III activity
GYM73_00760	COG0469	pyruvate kinase activity
GYM73_00775	COG1819	glycosyl
GYM73_00780	COG0596	Alpha beta hydrolase
GYM73_00790	COG0604	alcohol dehydrogenase
GYM73_00790	COG3321	synthase
GYM73_00795	COG3321	synthase
GYM73_00795	COG0604	alcohol dehydrogenase
GYM73_00800	COG0534	Mate efflux family protein
GYM73_00815	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GYM73_00845	COG0357	Ribosomal RNA small subunit methyltransferase G
GYM73_00850	COG2183	response to ionizing radiation
GYM73_00860	COG1610	YqeY-like protein
GYM73_00865	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GYM73_00880	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GYM73_00885	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GYM73_00890	COG0772	Belongs to the SEDS family
GYM73_00895	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GYM73_00900	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GYM73_00905	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GYM73_00920	COG0275	rRNA processing
GYM73_00925	COG2001	Belongs to the MraZ family
GYM73_00930	COG2267	carboxylic ester hydrolase activity
GYM73_00935	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GYM73_00940	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GYM73_00960	COG1185	polyribonucleotide nucleotidyltransferase activity
GYM73_00965	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GYM73_00975	COG1054	Belongs to the UPF0176 family
GYM73_00980	COG3590	peptidase
GYM73_00985	COG2884	Cell division ATP-binding protein ftsE
GYM73_01000	COG0297	glycogen (starch) synthase activity
GYM73_01000	COG0438	transferase activity, transferring glycosyl groups
GYM73_01010	COG0564	pseudouridine synthase activity
GYM73_01015	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GYM73_01020	COG1968	undecaprenyl-diphosphatase activity
GYM73_01030	COG2177	Part of the ABC transporter FtsEX involved in
GYM73_01035	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GYM73_01045	COG1271	oxidase subunit
GYM73_01055	COG1074	ATP-dependent DNA helicase activity
GYM73_01065	COG0792	nuclease activity
GYM73_01070	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GYM73_01075	COG5000	phosphorelay sensor kinase activity
GYM73_01085	COG1132	(ABC) transporter
GYM73_01100	COG0583	DNA-binding transcription factor activity
GYM73_01105	COG2855	membrane
GYM73_01110	COG0165	Argininosuccinate lyase
GYM73_01120	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
GYM73_01125	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
GYM73_01135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GYM73_01140	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
GYM73_01145	COG0137	argininosuccinate synthase activity
GYM73_01165	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GYM73_01165	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GYM73_01180	COG1674	ftsk spoiiie
GYM73_01185	COG0670	Belongs to the BI1 family
GYM73_01190	COG0698	ribose 5-phosphate isomerase
GYM73_01195	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GYM73_01200	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GYM73_01205	COG0440	acetolactate synthase activity
GYM73_01215	COG0028	Belongs to the TPP enzyme family
GYM73_01225	COG0473	3-isopropylmalate dehydrogenase activity
GYM73_01235	COG0066	3-isopropylmalate dehydratase activity
GYM73_01240	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GYM73_01245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
GYM73_01255	COG1119	ATPase activity
GYM73_01270	COG0084	hydrolase, TatD family'
GYM73_01275	COG3594	Acyltransferase
GYM73_01280	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GYM73_01285	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GYM73_01290	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GYM73_01295	COG0561	phosphatase activity
GYM73_01310	COG0247	lactate metabolic process
GYM73_01310	COG2181	nitrate reductase activity
GYM73_01315	COG0247	lactate metabolic process
GYM73_01315	COG2181	nitrate reductase activity
GYM73_01350	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GYM73_01355	COG2239	Acts as a magnesium transporter
GYM73_01370	COG1054	Belongs to the UPF0176 family
GYM73_01375	COG0815	Transfers the fatty acyl group on membrane lipoproteins
GYM73_01380	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GYM73_01385	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GYM73_01395	COG0552	protein localization to endoplasmic reticulum
GYM73_01405	COG0242	peptide deformylase activity
GYM73_01410	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GYM73_01455	COG2856	Zn peptidase
GYM73_01490	COG1393	Belongs to the ArsC family
GYM73_01500	COG0180	Tryptophanyl-tRNA synthetase
GYM73_01505	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GYM73_01515	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GYM73_01520	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GYM73_01525	COG0561	phosphatase activity
GYM73_01530	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GYM73_01620	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
GYM73_01625	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GYM73_01630	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GYM73_01650	COG2356	endonuclease I
GYM73_01685	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GYM73_01695	COG0463	Glycosyl transferase, family 2
GYM73_01700	COG0193	aminoacyl-tRNA hydrolase activity
GYM73_01705	COG0726	polysaccharide deacetylase
GYM73_01735	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GYM73_01755	COG3158	transport of potassium into the cell
GYM73_01760	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GYM73_01765	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GYM73_01770	COG1022	Amp-dependent synthetase and ligase
GYM73_01780	COG1136	(ABC) transporter
GYM73_01790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GYM73_01810	COG2217	Heavy metal translocating P-type atpase
GYM73_01815	COG0513	Belongs to the DEAD box helicase family
GYM73_01825	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GYM73_01830	COG1027	Aspartate ammonia-lyase
GYM73_01835	COG2985	domain, Protein
GYM73_01845	COG0252	asparaginase activity
GYM73_01860	COG4948	Mandelate Racemase Muconate Lactonizing
GYM73_01870	COG1556	Lactate utilization protein
GYM73_01875	COG1139	Iron-sulfur cluster binding protein
GYM73_01880	COG0247	lactate metabolic process
GYM73_01885	COG0037	tRNA processing
GYM73_01890	COG1295	ribonuclease BN
GYM73_01905	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GYM73_01910	COG0339	signal peptide processing
GYM73_01925	COG2003	Belongs to the UPF0758 family
GYM73_01980	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GYM73_02010	COG0542	response to heat
GYM73_02085	COG2137	regulation of response to DNA damage stimulus
GYM73_02090	COG3118	belongs to the thioredoxin family
GYM73_02105	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GYM73_02120	COG0156	8-amino-7-oxononanoate synthase activity
GYM73_02125	COG1490	D-aminoacyl-tRNA deacylase activity
GYM73_02130	COG2885	chlorophyll binding
GYM73_02135	COG0708	Exodeoxyribonuclease III
GYM73_02150	COG0641	radical SAM
GYM73_02175	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GYM73_02180	COG1028	Short-chain dehydrogenase reductase Sdr
GYM73_02210	COG0667	Aldo Keto reductase
GYM73_02215	COG1058	Belongs to the CinA family
GYM73_02215	COG1546	Belongs to the CinA family
GYM73_02220	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GYM73_02230	COG1227	inorganic diphosphatase activity
GYM73_02235	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GYM73_02245	COG2096	Adenosyltransferase
GYM73_02255	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GYM73_02265	COG3852	Histidine kinase
GYM73_02270	COG1137	ATPase activity
GYM73_02285	COG1252	NADH dehydrogenase
GYM73_02295	COG0739	heme binding
GYM73_02300	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GYM73_02340	COG1649	PFAM Uncharacterised BCR, COG1649
GYM73_02345	COG1086	Polysaccharide biosynthesis protein
GYM73_02350	COG0018	arginyl-trna synthetase
GYM73_02360	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GYM73_02385	COG3425	synthase
GYM73_02390	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GYM73_02395	COG0813	purine-nucleoside phosphorylase activity
GYM73_02400	COG2234	aminopeptidase activity
GYM73_02410	COG0739	heme binding
GYM73_02420	COG2759	Belongs to the formate--tetrahydrofolate ligase family
GYM73_02425	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GYM73_02430	COG1193	negative regulation of DNA recombination
GYM73_02435	COG3011	Protein conserved in bacteria
GYM73_02455	COG0799	negative regulation of ribosome biogenesis
GYM73_02460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GYM73_02470	COG4589	Belongs to the CDS family
GYM73_02475	COG0688	phosphatidylethanolamine metabolic process
GYM73_02480	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GYM73_02520	COG0542	response to heat
GYM73_02525	COG0738	Major facilitator superfamily
GYM73_02535	COG0531	amino acid
GYM73_02555	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GYM73_02565	COG0254	rRNA binding
GYM73_02570	COG0538	isocitrate dehydrogenase activity
GYM73_02575	COG0318	PFAM AMP-dependent synthetase and ligase
GYM73_02610	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GYM73_02615	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GYM73_02625	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GYM73_02630	COG0297	glycogen (starch) synthase activity
GYM73_02640	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GYM73_02645	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GYM73_02660	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GYM73_02665	COG1349	DNA-binding transcription factor activity
GYM73_02670	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GYM73_02675	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GYM73_02680	COG0371	Dehydrogenase
GYM73_02700	COG1069	ribulokinase activity
GYM73_02735	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GYM73_02745	COG0215	cysteine-tRNA ligase activity
GYM73_02750	COG0302	gtp cyclohydrolase
GYM73_02755	COG3339	Conserved Protein
GYM73_02760	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GYM73_02765	COG1979	alcohol dehydrogenase
GYM73_02770	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GYM73_02775	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GYM73_02780	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GYM73_02785	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GYM73_02790	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GYM73_02795	COG0356	it plays a direct role in the translocation of protons across the membrane
GYM73_02810	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GYM73_02815	COG0511	ligase activity, forming carbon-carbon bonds
GYM73_02820	COG0439	Biotin carboxylase
GYM73_02830	COG0617	tRNA 3'-terminal CCA addition
GYM73_02830	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GYM73_02830	COG0517	IMP dehydrogenase activity
GYM73_02840	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GYM73_02845	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GYM73_02850	COG0671	phosphoesterase, PA-phosphatase related
GYM73_02855	COG2211	Major facilitator Superfamily
GYM73_02865	COG0504	CTP synthase activity
GYM73_02870	COG0706	membrane insertase activity
GYM73_02880	COG0205	6-phosphofructokinase activity
GYM73_02885	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GYM73_02890	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GYM73_02920	COG0471	metal ion transport
GYM73_02925	COG4717	serine-type aminopeptidase activity
GYM73_02935	COG2326	polyphosphate kinase activity
GYM73_02940	COG1912	Pfam S-adenosyl-l-methionine hydroxide adenosyltransferase
GYM73_02945	COG1702	phosphate starvation-inducible protein PhoH
GYM73_02950	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GYM73_02965	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GYM73_02975	COG4152	abc transporter atp-binding protein
GYM73_02990	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GYM73_02995	COG0519	Catalyzes the synthesis of GMP from XMP
GYM73_03005	COG0735	belongs to the Fur family
GYM73_03010	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GYM73_03015	COG0516	GMP reductase activity
GYM73_03015	COG0517	IMP dehydrogenase activity
GYM73_03025	COG2814	Major facilitator Superfamily
GYM73_03030	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GYM73_03035	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GYM73_03040	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
GYM73_03045	COG0196	riboflavin kinase activity
GYM73_03055	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GYM73_03070	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GYM73_03085	COG1104	cysteine desulfurase activity
GYM73_03090	COG1301	dicarboxylic acid transport
GYM73_03095	COG1234	tRNA 3'-trailer cleavage
GYM73_03100	COG2252	PERMEase
GYM73_03105	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GYM73_03110	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GYM73_03115	COG2824	Alkylphosphonate utilization operon protein PhnA
GYM73_03125	COG2910	NAD(P)H-binding
GYM73_03135	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GYM73_03140	COG0698	ribose 5-phosphate isomerase
GYM73_03145	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GYM73_03155	COG2081	HI0933 family
GYM73_03175	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GYM73_03180	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GYM73_03190	COG1215	transferase activity, transferring glycosyl groups
GYM73_03200	COG1442	glycosyl transferase family 8
GYM73_03200	COG1216	Glycosyl transferase, family 2
GYM73_03240	COG0251	oxidation-reduction process
GYM73_03250	COG0860	N-Acetylmuramoyl-L-alanine amidase
GYM73_03255	COG1215	transferase activity, transferring glycosyl groups
GYM73_03260	COG0367	asparagine synthase
GYM73_03270	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GYM73_03280	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GYM73_03290	COG3275	phosphorelay sensor kinase activity
GYM73_03295	COG3279	Response regulator of the LytR AlgR family
GYM73_03330	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GYM73_03335	COG1408	metallophosphoesterase
GYM73_03345	COG0051	transcription antitermination factor activity, RNA binding
GYM73_03350	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GYM73_03355	COG0049	tRNA binding
GYM73_03360	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GYM73_03370	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GYM73_03380	COG0438	transferase activity, transferring glycosyl groups
GYM73_03385	COG0460	homoserine dehydrogenase
GYM73_03390	COG0626	cystathionine gamma-synthase activity
GYM73_03395	COG0789	Transcriptional regulator
GYM73_03400	COG1028	Short-chain dehydrogenase reductase Sdr
GYM73_03405	COG0495	leucyl-tRNA aminoacylation
GYM73_03420	COG3209	COG3209 Rhs family protein
GYM73_03450	COG3209	COG3209 Rhs family protein
GYM73_03460	COG3209	COG3209 Rhs family protein
GYM73_03520	COG0556	nucleotide-excision repair
GYM73_03530	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GYM73_03535	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GYM73_03550	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GYM73_03550	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GYM73_03560	COG1272	protein, Hemolysin III
GYM73_03565	COG0237	dephospho-CoA kinase activity
GYM73_03570	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GYM73_03570	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GYM73_03585	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GYM73_03600	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GYM73_03610	COG1959	2 iron, 2 sulfur cluster binding
GYM73_03630	COG0243	molybdopterin cofactor binding
GYM73_03635	COG0437	4 iron, 4 sulfur cluster binding
GYM73_03650	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
GYM73_03655	COG0303	'Molybdopterin
GYM73_03665	COG0746	molybdenum cofactor guanylyltransferase activity
GYM73_03685	COG2258	MOSC domain
GYM73_03695	COG0315	cyclic pyranopterin monophosphate synthase activity
GYM73_03695	COG0521	Mo-molybdopterin cofactor biosynthetic process
GYM73_03710	COG3842	ATPase activity
GYM73_03720	COG0322	excinuclease ABC activity
GYM73_03725	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GYM73_03780	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GYM73_03780	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GYM73_03835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GYM73_03840	COG0583	DNA-binding transcription factor activity
GYM73_03845	COG0492	ferredoxin-NADP+ reductase activity
GYM73_03860	COG0697	spore germination
GYM73_03865	COG1605	Chorismate mutase
GYM73_03865	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GYM73_03870	COG1162	GTPase activity
GYM73_03885	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GYM73_03895	COG0668	transmembrane transport
GYM73_03900	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GYM73_03910	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GYM73_03935	COG2027	D-alanyl-D-alanine carboxypeptidase
GYM73_03950	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GYM73_03965	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GYM73_03970	COG0484	heat shock protein binding
GYM73_03985	COG0508	dehydrogenase complex catalyzes the overall conversion of
GYM73_04015	COG1216	Glycosyl transferase, family 2
GYM73_04015	COG1442	glycosyl transferase family 8
GYM73_04175	COG0110	maltose O-acetyltransferase activity
GYM73_04220	COG0489	protein tyrosine kinase activity
GYM73_04245	COG0477	Major facilitator Superfamily
GYM73_04265	COG0017	Asparaginyl-tRNA synthetase
GYM73_04295	COG0167	dihydroorotate dehydrogenase activity
GYM73_04310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GYM73_04310	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GYM73_04335	COG0544	peptidyl-prolyl cis-trans isomerase activity
GYM73_04345	COG0742	ribosomal rna small subunit methyltransferase
GYM73_04350	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GYM73_04355	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GYM73_04360	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GYM73_04375	COG0006	proline dipeptidase activity
GYM73_04425	COG2195	Cleaves the N-terminal amino acid of tripeptides
GYM73_04430	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GYM73_04440	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
GYM73_04445	COG3001	Fructosamine kinase
GYM73_04450	COG0805	protein transport
GYM73_04460	COG0514	ATP-dependent DNA helicase (RecQ)
GYM73_04465	COG1428	Deoxynucleoside kinase
GYM73_04475	COG2264	protein methyltransferase activity
GYM73_04490	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GYM73_04510	COG0463	Glycosyl transferase, family 2
GYM73_04520	COG1215	transferase activity, transferring glycosyl groups
GYM73_04565	COG2217	Heavy metal translocating P-type atpase
GYM73_04575	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GYM73_04580	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GYM73_04585	COG0259	pyridoxamine-phosphate oxidase activity
GYM73_04590	COG1678	Uncharacterized ACR, COG1678
GYM73_04595	COG1363	Peptidase, m42
GYM73_04605	COG1333	cytochrome c biogenesis protein
GYM73_04605	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GYM73_04615	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GYM73_04630	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GYM73_04630	COG1328	CTP reductase activity
GYM73_04635	COG0602	queuosine metabolic process
GYM73_04650	COG1704	LemA family
GYM73_04665	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GYM73_04685	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GYM73_04690	COG0484	heat shock protein binding
GYM73_04700	COG0242	peptide deformylase activity
GYM73_04705	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GYM73_04710	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GYM73_04725	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GYM73_04740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GYM73_04745	COG0424	maF-like protein
GYM73_04755	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GYM73_04770	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GYM73_04775	COG0667	Aldo Keto reductase
GYM73_04795	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GYM73_04805	COG1595	DNA-templated transcription, initiation
GYM73_04815	COG1131	(ABC) transporter
GYM73_04820	COG0077	Prephenate dehydratase
GYM73_04820	COG1605	Chorismate mutase
GYM73_04835	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GYM73_04840	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GYM73_04840	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GYM73_04845	COG1496	oxidoreductase activity
GYM73_04860	COG1132	(ABC) transporter
GYM73_04870	COG1192	Involved in chromosome partitioning
GYM73_04875	COG1475	DNA binding
GYM73_04885	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GYM73_04890	COG0681	Belongs to the peptidase S26 family
GYM73_04905	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GYM73_04940	COG1113	amino acid transport
GYM73_04950	COG0326	Molecular chaperone. Has ATPase activity
GYM73_04960	COG0322	excinuclease ABC activity
GYM73_04965	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GYM73_04980	COG1022	Amp-dependent synthetase and ligase
GYM73_04995	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GYM73_05030	COG0252	asparaginase activity
GYM73_05050	COG0187	DNA topoisomerase II activity
GYM73_05055	COG0149	triose-phosphate isomerase activity
GYM73_05075	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GYM73_05080	COG3830	Belongs to the UPF0237 family
GYM73_05080	COG0560	Phosphoserine phosphatase
GYM73_05085	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GYM73_05090	COG3338	carbonate dehydratase activity
GYM73_05105	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GYM73_05110	COG0492	ferredoxin-NADP+ reductase activity
GYM73_05125	COG0335	large ribosomal subunit rRNA binding
GYM73_05130	COG0012	GTP binding
GYM73_05140	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GYM73_05145	COG0028	Belongs to the TPP enzyme family
GYM73_05150	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GYM73_05155	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GYM73_05160	COG4206	TonB-dependent receptor
GYM73_05165	COG3118	belongs to the thioredoxin family
GYM73_05180	COG0463	Glycosyl transferase, family 2
GYM73_05190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GYM73_05200	COG1045	serine acetyltransferase
GYM73_05210	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GYM73_05215	COG0359	binds to the 23S rRNA
GYM73_05220	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GYM73_05225	COG0360	Binds together with S18 to 16S ribosomal RNA
GYM73_05230	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GYM73_05245	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GYM73_05250	COG1053	succinate dehydrogenase
GYM73_05280	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GYM73_05285	COG1181	Belongs to the D-alanine--D-alanine ligase family
GYM73_05295	COG0564	pseudouridine synthase activity
GYM73_05300	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GYM73_05305	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GYM73_05320	COG0525	valine-tRNA ligase activity
GYM73_05325	COG0577	efflux transmembrane transporter activity
GYM73_05325	COG1136	(ABC) transporter
GYM73_05330	COG0577	efflux transmembrane transporter activity
GYM73_05330	COG1136	(ABC) transporter
GYM73_05335	COG1136	(ABC) transporter
GYM73_05340	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GYM73_05350	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GYM73_05385	COG2890	protein-(glutamine-N5) methyltransferase activity
GYM73_05390	COG0653	protein targeting
GYM73_05405	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GYM73_05410	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GYM73_05415	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GYM73_05420	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GYM73_05425	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GYM73_05425	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
GYM73_05430	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GYM73_05435	COG1078	dGTPase activity
GYM73_05440	COG2204	response regulator
GYM73_05465	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GYM73_05470	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GYM73_05475	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GYM73_05485	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GYM73_05510	COG0497	DNA recombination
GYM73_05515	COG2249	NAD(P)H dehydrogenase (quinone) activity
GYM73_05520	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GYM73_05535	COG0508	dehydrogenase complex catalyzes the overall conversion of
GYM73_05545	COG1597	lipid kinase activity
GYM73_05550	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GYM73_05555	COG0745	RESPONSE REGULATOR receiver
GYM73_05555	COG2205	protein histidine kinase activity
GYM73_05555	COG3292	Two component regulator propeller
GYM73_05595	COG0436	Aminotransferase
GYM73_05600	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GYM73_05605	COG1663	tetraacyldisaccharide 4'-kinase activity
GYM73_05655	COG0534	Mate efflux family protein
GYM73_05660	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
GYM73_05670	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GYM73_05680	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
GYM73_05685	COG2207	Transcriptional regulator
GYM73_05685	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GYM73_05710	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GYM73_05715	COG0563	adenylate kinase activity
GYM73_05720	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GYM73_05725	COG0589	response to stress
GYM73_05730	COG0750	zinc metalloprotease
GYM73_05740	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GYM73_05745	COG0438	transferase activity, transferring glycosyl groups
GYM73_05775	COG1442	glycosyl transferase family 8
GYM73_05775	COG1216	Glycosyl transferase, family 2
GYM73_05780	COG1216	Glycosyl transferase, family 2
GYM73_05780	COG1442	glycosyl transferase family 8
GYM73_05790	COG2244	polysaccharide biosynthetic process
GYM73_05810	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GYM73_05815	COG0793	Belongs to the peptidase S41A family
GYM73_05820	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GYM73_05830	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GYM73_05835	COG2704	Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane
GYM73_05840	COG1120	ATPase activity
GYM73_05850	COG0277	FAD linked oxidase domain protein
GYM73_05880	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
GYM73_05895	COG2365	Tyrosine phosphatase family
GYM73_05900	COG2217	Heavy metal translocating P-type atpase
GYM73_05925	COG4771	TonB-dependent receptor
GYM73_05965	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GYM73_06020	COG3179	chitinase
GYM73_06035	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GYM73_06040	COG0228	four-way junction DNA binding
GYM73_06045	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GYM73_06050	COG0825	malonyl-CoA metabolic process
GYM73_06055	COG1418	mRNA catabolic process
GYM73_06065	COG0642	Histidine kinase
GYM73_06070	COG0745	RESPONSE REGULATOR receiver
GYM73_06080	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GYM73_06095	COG4574	serine-type endopeptidase inhibitor activity
GYM73_06105	COG0022	dehydrogenase e1 component
GYM73_06110	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GYM73_06125	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GYM73_06140	COG0673	inositol 2-dehydrogenase activity
GYM73_06150	COG0656	L-ascorbic acid biosynthetic process
GYM73_06160	COG4221	oxidoreductase activity
GYM73_06180	COG1611	Belongs to the LOG family
GYM73_06195	COG2885	chlorophyll binding
GYM73_06195	COG3047	cAMP biosynthetic process
GYM73_06215	COG1917	Cupin 2, conserved barrel domain protein
GYM73_06215	COG2207	Transcriptional regulator
GYM73_06220	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GYM73_06220	COG2755	lipolytic protein G-D-S-L family
GYM73_06275	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GYM73_06320	COG4206	TonB-dependent receptor
GYM73_06330	COG1007	ATP synthesis coupled electron transport
GYM73_06345	COG1619	proteins homologs of microcin C7 resistance protein MccF
GYM73_06380	COG0519	Catalyzes the synthesis of GMP from XMP
GYM73_06380	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GYM73_06395	COG2195	Cleaves the N-terminal amino acid of tripeptides
GYM73_06415	COG0753	catalase activity
GYM73_06425	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GYM73_06440	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GYM73_06450	COG1902	pentaerythritol trinitrate reductase activity
GYM73_06470	COG0138	bifunctional purine biosynthesis protein purh
GYM73_06485	COG0724	RNA recognition motif
GYM73_06495	COG0509	glycine decarboxylation via glycine cleavage system
GYM73_06505	COG0632	four-way junction helicase activity
GYM73_06525	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GYM73_06535	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GYM73_06540	COG0539	negative regulation of cytoplasmic translation
GYM73_06590	COG0300	oxidoreductase activity
GYM73_06595	COG0783	Belongs to the Dps family
GYM73_06620	COG0443	Heat shock 70 kDa protein
GYM73_06635	COG1126	abc transporter atp-binding protein
GYM73_06650	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GYM73_06665	COG0463	Glycosyl transferase, family 2
GYM73_06670	COG2954	triphosphatase activity
GYM73_06680	COG1335	isochorismatase
GYM73_06685	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
GYM73_06690	COG4975	Glucose uptake
GYM73_06695	COG1028	Short-chain dehydrogenase reductase Sdr
GYM73_06700	COG2706	6-phosphogluconolactonase activity
GYM73_06705	COG0148	phosphopyruvate hydratase activity
GYM73_06725	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GYM73_06725	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GYM73_06745	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GYM73_06760	COG0527	aspartate kinase activity
GYM73_06780	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GYM73_06785	COG1733	regulation of RNA biosynthetic process
GYM73_06815	COG0606	chelatase, subunit chli
GYM73_06825	COG1217	gtp-binding protein TYPA
GYM73_06830	COG3118	belongs to the thioredoxin family
GYM73_06835	COG0321	lipoyl(octanoyl) transferase activity
GYM73_06845	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GYM73_06845	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GYM73_06850	COG1739	Uncharacterized protein family UPF0029
GYM73_06855	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GYM73_06860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GYM73_06870	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GYM73_06875	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GYM73_06885	COG0776	regulation of translation
GYM73_06905	COG1253	flavin adenine dinucleotide binding
GYM73_06925	COG0546	phosphoglycolate phosphatase activity
GYM73_06930	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GYM73_06935	COG0004	ammonium transporteR
GYM73_06945	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GYM73_06985	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GYM73_06995	COG0586	Pfam SNARE associated Golgi protein
GYM73_07000	COG1595	DNA-templated transcription, initiation
GYM73_07015	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GYM73_07030	COG1981	membrane
GYM73_07035	COG3477	response to acidic pH
GYM73_07040	COG0124	histidyl-tRNA synthetase
GYM73_07065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GYM73_07075	COG0423	glycine-tRNA ligase activity
GYM73_07080	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GYM73_07085	COG4974	Belongs to the 'phage' integrase family
GYM73_07090	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GYM73_07135	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GYM73_07140	COG0081	regulation of translation
GYM73_07145	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GYM73_07150	COG0222	ribosome binding
GYM73_07155	COG0085	RNA polymerase activity
GYM73_07160	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GYM73_07170	COG1629	transport
GYM73_07180	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
GYM73_07195	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GYM73_07200	COG1522	sequence-specific DNA binding
GYM73_07215	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GYM73_07220	COG2226	methyltransferase
GYM73_07240	COG0531	amino acid
GYM73_07245	COG1012	belongs to the aldehyde dehydrogenase family
GYM73_07265	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GYM73_07270	COG2814	Major facilitator Superfamily
GYM73_07275	COG0656	L-ascorbic acid biosynthetic process
GYM73_07290	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
GYM73_07325	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GYM73_07330	COG2166	iron-sulfur cluster assembly
GYM73_07340	COG0508	dehydrogenase complex catalyzes the overall conversion of
GYM73_07340	COG0022	dehydrogenase e1 component
GYM73_07345	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GYM73_07365	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GYM73_07370	COG0772	Belongs to the SEDS family
GYM73_07380	COG1792	Involved in formation and maintenance of cell shape
GYM73_07390	COG0616	signal peptide processing
GYM73_07395	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
GYM73_07395	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GYM73_07400	COG2885	chlorophyll binding
GYM73_07405	COG0203	ribosomal protein L17
GYM73_07410	COG0202	RNA polymerase activity
GYM73_07415	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GYM73_07420	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GYM73_07425	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GYM73_07430	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GYM73_07435	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GYM73_07440	COG0201	protein transport
GYM73_07445	COG0200	Binds to the 23S rRNA
GYM73_07450	COG1841	ribosomal large subunit assembly
GYM73_07455	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GYM73_07460	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GYM73_07465	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GYM73_07470	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GYM73_07475	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GYM73_07480	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GYM73_07490	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GYM73_07495	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GYM73_07500	COG0255	Belongs to the universal ribosomal protein uL29 family
GYM73_07505	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GYM73_07510	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GYM73_07515	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GYM73_07520	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GYM73_07525	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GYM73_07530	COG0089	rRNA binding
GYM73_07535	COG0088	Forms part of the polypeptide exit tunnel
GYM73_07540	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GYM73_07605	COG1505	serine-type exopeptidase activity
GYM73_07610	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GYM73_07610	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GYM73_07625	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GYM73_07640	COG1210	Utp--glucose-1-phosphate uridylyltransferase
GYM73_07645	COG0756	dUTP diphosphatase activity
GYM73_07650	COG0433	COG0433 Predicted ATPase
GYM73_07655	COG2176	DNA-directed DNA polymerase activity
GYM73_07660	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GYM73_07675	COG0019	diaminopimelate decarboxylase activity
GYM73_07755	COG0745	RESPONSE REGULATOR receiver
GYM73_07760	COG5002	protein histidine kinase activity
GYM73_07790	COG2353	YceI-like domain
GYM73_07795	COG0646	methionine synthase
GYM73_07795	COG1410	methionine synthase
GYM73_07805	COG0586	Pfam SNARE associated Golgi protein
GYM73_07810	COG1301	dicarboxylic acid transport
GYM73_07825	COG0842	Transport permease protein
GYM73_07830	COG1131	(ABC) transporter
GYM73_07835	COG1131	(ABC) transporter
GYM73_07855	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GYM73_07865	COG0105	UTP biosynthetic process
GYM73_07870	COG0295	cytidine deaminase activity
GYM73_07875	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GYM73_07890	COG1024	Enoyl-CoA hydratase
GYM73_07890	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GYM73_07895	COG0183	Belongs to the thiolase family
GYM73_07910	COG2223	nitrite transmembrane transporter activity
GYM73_07930	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GYM73_07935	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GYM73_07945	COG0131	Imidazoleglycerol-phosphate dehydratase
GYM73_07950	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
GYM73_07955	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GYM73_07960	COG0107	imidazoleglycerol-phosphate synthase activity
GYM73_07965	COG0140	phosphoribosyl-ATP diphosphatase activity
GYM73_07965	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GYM73_07970	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GYM73_07975	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GYM73_07985	COG0488	(ABC) transporter
GYM73_07990	COG0730	response to heat
GYM73_08010	COG0204	Acyl-transferase
GYM73_08015	COG1482	cell wall glycoprotein biosynthetic process
GYM73_08030	COG0598	Magnesium transport protein CorA
GYM73_08035	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GYM73_08060	COG0463	Glycosyl transferase, family 2
GYM73_08065	COG0039	L-malate dehydrogenase activity
GYM73_08070	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GYM73_08085	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GYM73_08105	COG1770	oligopeptidase
GYM73_08110	COG0393	Putative heavy-metal-binding
GYM73_08125	COG0649	NAD binding
GYM73_08130	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GYM73_08135	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GYM73_08140	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GYM73_08145	COG4774	siderophore transport
GYM73_08240	COG1160	GTP binding
GYM73_08265	COG0437	4 iron, 4 sulfur cluster binding
GYM73_08275	COG0470	DNA polymerase III
GYM73_08280	COG0305	Participates in initiation and elongation during chromosome replication
GYM73_08285	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GYM73_08290	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GYM73_08295	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GYM73_08300	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GYM73_08305	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GYM73_08310	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GYM73_08315	COG2076	Multidrug Resistance protein
GYM73_08320	COG2255	four-way junction helicase activity
GYM73_08325	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GYM73_08330	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
GYM73_08335	COG0713	ATP synthesis coupled electron transport
GYM73_08345	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
GYM73_08350	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
GYM73_08355	COG1034	ATP synthesis coupled electron transport
GYM73_08395	COG0527	aspartate kinase activity
GYM73_08395	COG0460	homoserine dehydrogenase
GYM73_08400	COG0083	homoserine kinase activity
GYM73_08405	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
GYM73_08410	COG0528	UMP kinase activity
GYM73_08415	COG0233	cytoplasmic translational termination
GYM73_08420	COG0287	Prephenate dehydrogenase
GYM73_08430	COG0336	Belongs to the RNA methyltransferase TrmD family
GYM73_08450	COG1522	sequence-specific DNA binding
GYM73_08455	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GYM73_08465	COG0306	phosphate transporter
GYM73_08475	COG0358	DNA primase activity
GYM73_08490	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GYM73_08520	COG0488	(ABC) transporter
GYM73_08530	COG2217	Heavy metal translocating P-type atpase
GYM73_08550	COG0348	domain, Protein
GYM73_08565	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GYM73_08585	COG1774	PSP1 C-terminal conserved region
GYM73_08625	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GYM73_08635	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GYM73_08645	COG3842	ATPase activity
GYM73_08655	COG1970	mechanosensitive ion channel activity
GYM73_08670	COG0442	prolyl-tRNA aminoacylation
GYM73_08675	COG1519	Transferase
GYM73_08675	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GYM73_08680	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GYM73_08685	COG2151	metal-sulfur cluster biosynthetic enzyme
GYM73_08695	COG0594	ribonuclease P activity
GYM73_08715	COG2304	oxidoreductase activity
GYM73_08720	COG2304	oxidoreductase activity
GYM73_08735	COG0714	Associated with various cellular activities
GYM73_08740	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GYM73_08750	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GYM73_08760	COG0826	peptidase U32
GYM73_08770	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GYM73_08805	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GYM73_08820	COG0045	succinate-CoA ligase (ADP-forming) activity
GYM73_08835	COG0823	Involved in the tonB-independent uptake of proteins
GYM73_08835	COG1506	peptidase
GYM73_08840	COG0588	phosphoglycerate mutase activity
GYM73_08855	COG0268	Binds directly to 16S ribosomal RNA
GYM73_08870	COG0285	dihydrofolate synthase activity
GYM73_08880	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GYM73_08885	COG0612	Peptidase, M16
GYM73_08890	COG0009	L-threonylcarbamoyladenylate synthase
GYM73_08895	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GYM73_08900	COG0628	permease
GYM73_08905	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GYM73_08925	COG0778	Nitroreductase
GYM73_08930	COG1846	Transcriptional regulator
GYM73_08940	COG2011	ABC-type metal ion transport system permease component
GYM73_08945	COG1464	Belongs to the NlpA lipoprotein family
GYM73_08950	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GYM73_08965	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GYM73_08970	COG1132	(ABC) transporter
GYM73_08980	COG0791	NLP P60 protein
GYM73_08995	COG2333	competence protein COMEC
GYM73_08995	COG0658	competence protein
GYM73_09010	COG0668	transmembrane transport
GYM73_09020	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GYM73_09025	COG0857	belongs to the CobB CobQ family
GYM73_09025	COG0280	phosphate acetyltransferase
GYM73_09030	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
GYM73_09030	COG0321	lipoyl(octanoyl) transferase activity
GYM73_09045	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GYM73_09055	COG2515	1-aminocyclopropane-1-carboxylate deaminase
GYM73_09060	COG3104	oligopeptide transport
GYM73_09065	COG3104	oligopeptide transport
GYM73_09100	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GYM73_09115	COG3586	endonuclease activity
GYM73_09135	COG3023	N-Acetylmuramoyl-L-alanine amidase
GYM73_09140	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
GYM73_09165	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GYM73_09170	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GYM73_09170	COG0284	orotidine-5'-phosphate decarboxylase activity
GYM73_09180	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GYM73_09180	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GYM73_09185	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GYM73_09190	COG0602	queuosine metabolic process
GYM73_09195	COG0450	alkyl hydroperoxide reductase
GYM73_09210	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GYM73_09215	COG0113	porphobilinogen synthase activity
GYM73_09230	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GYM73_09235	COG0217	transcriptional regulatory protein
GYM73_09245	COG1472	Belongs to the glycosyl hydrolase 3 family
GYM73_09250	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GYM73_09255	COG0737	Belongs to the 5'-nucleotidase family
GYM73_09270	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GYM73_09275	COG1216	Glycosyl transferase, family 2
GYM73_09280	COG1216	Glycosyl transferase, family 2
GYM73_09305	COG1216	Glycosyl transferase, family 2
GYM73_09350	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GYM73_09365	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GYM73_09370	COG0436	Aminotransferase
GYM73_09380	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GYM73_09390	COG2732	(Barnase) inhibitor
GYM73_09395	COG0463	Glycosyl transferase, family 2
GYM73_09410	COG0823	Involved in the tonB-independent uptake of proteins
GYM73_09410	COG1506	peptidase
GYM73_09430	COG1380	Effector of murein hydrolase LrgA
GYM73_09435	COG1346	cytolysis
GYM73_09440	COG0557	exoribonuclease II activity
GYM73_09445	COG2169	Transcriptional regulator
GYM73_09445	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GYM73_09450	COG0159	tryptophan synthase activity
GYM73_09455	COG0135	phosphoribosylanthranilate isomerase activity
GYM73_09460	COG0134	indole-3-glycerol-phosphate synthase activity
GYM73_09470	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GYM73_09475	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GYM73_09475	COG0512	Glutamine amidotransferase of anthranilate synthase
GYM73_09480	COG1335	isochorismatase
GYM73_09485	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GYM73_09490	COG0133	tryptophan synthase activity
GYM73_09495	COG3047	cAMP biosynthetic process
GYM73_09495	COG2885	chlorophyll binding
GYM73_09505	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GYM73_09505	COG0140	phosphoribosyl-ATP diphosphatase activity
GYM73_09510	COG0811	peptide transport
GYM73_09515	COG0848	biopolymer transport protein
GYM73_09525	COG0719	Fe-S assembly protein
GYM73_09535	COG0316	Belongs to the HesB IscA family
GYM73_09540	COG2267	carboxylic ester hydrolase activity
GYM73_09555	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GYM73_09565	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GYM73_09570	COG0181	hydroxymethylbilane synthase activity
GYM73_09575	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GYM73_09585	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GYM73_09605	COG1132	(ABC) transporter
GYM73_09610	COG0101	tRNA pseudouridine synthase activity
GYM73_09630	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GYM73_09635	COG0460	homoserine dehydrogenase
GYM73_09635	COG0527	aspartate kinase activity
GYM73_09645	COG0126	phosphoglycerate kinase activity
GYM73_09655	COG0445	tRNA wobble uridine modification
GYM73_09660	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GYM73_09665	COG1752	Esterase of the alpha-beta hydrolase superfamily
GYM73_09680	COG0438	transferase activity, transferring glycosyl groups
GYM73_09690	COG0438	transferase activity, transferring glycosyl groups
GYM73_09695	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GYM73_09700	COG0438	transferase activity, transferring glycosyl groups
GYM73_09745	COG0477	Major facilitator Superfamily
GYM73_09745	COG2814	Major facilitator Superfamily
GYM73_09755	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GYM73_09760	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
GYM73_09760	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
GYM73_09770	COG0667	Aldo Keto reductase
GYM73_09775	COG0300	oxidoreductase activity
GYM73_09795	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
GYM73_09810	COG0584	glycerophosphoryl diester phosphodiesterase
GYM73_09815	COG2271	Major facilitator Superfamily
GYM73_09820	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GYM73_09825	COG1349	DNA-binding transcription factor activity
GYM73_09830	COG0247	lactate metabolic process
GYM73_09840	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
GYM73_09845	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
GYM73_09850	COG1113	amino acid transport
GYM73_09855	COG0596	Alpha beta hydrolase
GYM73_09870	COG1214	PFAM Peptidase M22, glycoprotease
GYM73_09900	COG3179	chitinase