locus-tag	class	description
MOO46_00005	COG1316	TRANSCRIPTIONal
MOO46_00010	COG0697	spore germination
MOO46_00015	COG0588	phosphoglycerate mutase activity
MOO46_00025	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
MOO46_00030	COG0756	dUTP diphosphatase activity
MOO46_00040	COG4956	integral membrane protein (PIN domain superfamily)
MOO46_00045	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
MOO46_00050	COG0215	cysteine-tRNA ligase activity
MOO46_00055	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
MOO46_00060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MOO46_00065	COG3688	RNA-binding protein containing a PIN domain
MOO46_00075	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MOO46_00085	COG0250	Participates in transcription elongation, termination and antitermination
MOO46_00090	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
MOO46_00095	COG0081	regulation of translation
MOO46_00100	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
MOO46_00105	COG0222	ribosome binding
MOO46_00110	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MOO46_00110	COG0392	lysyltransferase activity
MOO46_00120	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
MOO46_00125	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
MOO46_00130	COG2813	Specifically methylates the guanine in position
MOO46_00145	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
MOO46_00155	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
MOO46_00165	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
MOO46_00170	COG3870	Protein conserved in bacteria
MOO46_00175	COG0470	DNA polymerase III
MOO46_00180	COG4467	Involved in initiation control of chromosome replication
MOO46_00185	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
MOO46_00195	COG1214	PFAM Peptidase M22, glycoprotease
MOO46_00205	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
MOO46_00210	COG0488	(ABC) transporter
MOO46_00215	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
MOO46_00220	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
MOO46_00225	COG0459	protein refolding
MOO46_00230	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MOO46_00235	COG1739	Uncharacterized protein family UPF0029
MOO46_00240	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
MOO46_00245	COG1040	competence protein
MOO46_00250	COG0653	protein targeting
MOO46_00260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MOO46_00270	COG1950	PFAM Membrane protein of
MOO46_00275	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
MOO46_00280	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
MOO46_00285	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
MOO46_00295	COG0492	ferredoxin-NADP+ reductase activity
MOO46_00300	COG0556	nucleotide-excision repair
MOO46_00305	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MOO46_00310	COG0391	Required for morphogenesis under gluconeogenic growth conditions
MOO46_00315	COG1481	regulation of sporulation
MOO46_00320	COG0740	serine-type endopeptidase activity
MOO46_00335	COG0126	phosphoglycerate kinase activity
MOO46_00340	COG0149	triose-phosphate isomerase activity
MOO46_00345	COG0148	phosphopyruvate hydratase activity
MOO46_00350	COG0038	chloride channel
MOO46_00355	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
MOO46_00360	COG0557	exoribonuclease II activity
MOO46_00370	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
MOO46_00375	COG0280	phosphate acetyltransferase
MOO46_00380	COG0802	atpase or kinase
MOO46_00390	COG2176	DNA-directed DNA polymerase activity
MOO46_00395	COG0812	UDP-N-acetylmuramate dehydrogenase activity
MOO46_00400	COG0025	NhaP-type Na H and K H
MOO46_00425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MOO46_00430	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
MOO46_00435	COG1388	LysM domain
MOO46_00435	COG1705	Flagellar rod assembly protein muramidase FlgJ
MOO46_00440	COG1134	teichoic acid transport
MOO46_00460	COG3158	transport of potassium into the cell
MOO46_00465	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
MOO46_00485	COG4975	Glucose uptake
MOO46_00490	COG1846	Transcriptional regulator
MOO46_00495	COG2814	Major facilitator Superfamily
MOO46_00500	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
MOO46_00505	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MOO46_00520	COG0017	Asparaginyl-tRNA synthetase
MOO46_00530	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MOO46_00540	COG0406	alpha-ribazole phosphatase activity
MOO46_00575	COG1132	(ABC) transporter
MOO46_00580	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
MOO46_00585	COG3442	glutamine amidotransferase
MOO46_00590	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MOO46_00595	COG1435	thymidine kinase activity
MOO46_00605	COG2890	protein-(glutamine-N5) methyltransferase activity
MOO46_00610	COG0009	L-threonylcarbamoyladenylate synthase
MOO46_00615	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
MOO46_00620	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
MOO46_00625	COG0356	it plays a direct role in the translocation of protons across the membrane
MOO46_00630	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MOO46_00635	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
MOO46_00640	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
MOO46_00650	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
MOO46_00655	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
MOO46_00660	COG0355	proton-transporting ATP synthase activity, rotational mechanism
MOO46_00665	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MOO46_00670	COG1077	Cell shape determining protein MreB Mrl
MOO46_00675	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
MOO46_00685	COG0772	Belongs to the SEDS family
MOO46_00690	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MOO46_00695	COG2011	ABC-type metal ion transport system permease component
MOO46_00700	COG1464	Belongs to the NlpA lipoprotein family
MOO46_00705	COG2188	Transcriptional regulator
MOO46_00710	COG1131	(ABC) transporter
MOO46_00730	COG1181	Belongs to the D-alanine--D-alanine ligase family
MOO46_00735	COG2818	Glycosylase
MOO46_00745	COG2801	Transposase and inactivated derivatives
MOO46_00755	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
MOO46_00765	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
MOO46_00770	COG1956	GAF domain-containing protein
MOO46_00775	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
MOO46_00780	COG1104	cysteine desulfurase activity
MOO46_00785	COG0301	tRNA thio-modification
MOO46_00790	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
MOO46_00795	COG0525	valine-tRNA ligase activity
MOO46_00800	COG0285	dihydrofolate synthase activity
MOO46_00805	COG1077	Cell shape determining protein MreB Mrl
MOO46_00810	COG1792	Involved in formation and maintenance of cell shape
MOO46_00820	COG0850	regulation of cytokinetic process
MOO46_00825	COG2894	cell division
MOO46_00830	COG0765	amino acid transport
MOO46_00835	COG1126	abc transporter atp-binding protein
MOO46_00840	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
MOO46_00845	COG0612	Peptidase, M16
MOO46_00850	COG0612	Peptidase, M16
MOO46_00855	COG1426	Protein conserved in bacteria
MOO46_00865	COG1058	Belongs to the CinA family
MOO46_00865	COG1546	Belongs to the CinA family
MOO46_00870	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
MOO46_00880	COG1692	metallophosphoesterase
MOO46_00885	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
MOO46_00890	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
MOO46_00900	COG2255	four-way junction helicase activity
MOO46_00905	COG1862	Preprotein translocase
MOO46_00910	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
MOO46_00915	COG0513	Belongs to the DEAD box helicase family
MOO46_00920	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
MOO46_00925	COG4472	Bacterial protein of unknown function (DUF965)
MOO46_00930	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
MOO46_00935	COG3906	Belongs to the UPF0473 family
MOO46_00950	COG1193	negative regulation of DNA recombination
MOO46_00955	COG3118	belongs to the thioredoxin family
MOO46_00965	COG1719	4-vinyl reductase, 4VR
MOO46_00975	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
MOO46_00990	COG1609	Transcriptional regulator
MOO46_00995	COG0217	transcriptional regulatory protein
MOO46_01000	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
MOO46_01010	COG4537	Required for transformation and DNA binding
MOO46_01025	COG0827	DNA restriction-modification system
MOO46_01035	COG1113	amino acid transport
MOO46_01040	COG0737	Belongs to the 5'-nucleotidase family
MOO46_01045	COG4470	Protein conserved in bacteria
MOO46_01050	COG0647	UMP catabolic process
MOO46_01060	COG0586	Pfam SNARE associated Golgi protein
MOO46_01065	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
MOO46_01135	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
MOO46_01140	COG0477	Major facilitator Superfamily
MOO46_01145	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
MOO46_01150	COG0495	leucyl-tRNA aminoacylation
MOO46_01155	COG2244	polysaccharide biosynthetic process
MOO46_01165	COG2801	Transposase and inactivated derivatives
MOO46_01170	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
MOO46_01195	COG1428	Deoxynucleoside kinase
MOO46_01230	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MOO46_01240	COG0367	asparagine synthase
MOO46_01255	COG1794	racemase activity, acting on amino acids and derivatives
MOO46_01275	COG0018	arginyl-trna synthetase
MOO46_01280	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
MOO46_01285	COG0420	3'-5' exonuclease activity
MOO46_01290	COG4717	serine-type aminopeptidase activity
MOO46_01295	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
MOO46_01305	COG0537	adenosine 5'-monophosphoramidase activity
MOO46_01310	COG1131	(ABC) transporter
MOO46_01320	COG0220	tRNA (guanine-N7-)-methyltransferase activity
MOO46_01330	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
MOO46_01335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MOO46_01340	COG1674	ftsk spoiiie
MOO46_01345	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
MOO46_01350	COG0670	Belongs to the BI1 family
MOO46_01355	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MOO46_01355	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
MOO46_01360	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
MOO46_01370	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
MOO46_01375	COG3611	Membrane attachment protein
MOO46_01380	COG1484	DNA-dependent DNA replication
MOO46_01385	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
MOO46_01390	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
MOO46_01395	COG0291	Belongs to the bacterial ribosomal protein bL35 family
MOO46_01400	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
MOO46_01410	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
MOO46_01415	COG1534	Rna-binding protein
MOO46_01420	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
MOO46_01425	COG1713	HD superfamily hydrolase involved in NAD metabolism
MOO46_01430	COG0799	negative regulation of ribosome biogenesis
MOO46_01435	COG2226	methyltransferase
MOO46_01440	COG1323	Belongs to the UPF0348 family
MOO46_01450	COG0333	Belongs to the bacterial ribosomal protein bL32 family
MOO46_01455	COG1064	alcohol dehydrogenase
MOO46_01460	COG0745	RESPONSE REGULATOR receiver
MOO46_01465	COG5002	protein histidine kinase activity
MOO46_01470	COG0706	membrane insertase activity
MOO46_01480	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
MOO46_01490	COG1733	regulation of RNA biosynthetic process
MOO46_01495	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
MOO46_01500	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MOO46_01500	COG0072	phenylalanine-tRNA ligase activity
MOO46_01505	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
MOO46_01510	COG0572	uridine kinase
MOO46_01515	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
MOO46_01525	COG0768	penicillin binding
MOO46_01530	COG0267	Belongs to the bacterial ribosomal protein bL33 family
MOO46_01535	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
MOO46_01540	COG0457	Tetratricopeptide repeat
MOO46_01540	COG0705	Rhomboid family
MOO46_01550	COG1940	carbohydrate kinase activity
MOO46_01555	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
MOO46_01570	COG0789	Transcriptional regulator
MOO46_01575	COG0174	glutamine synthetase
MOO46_01590	COG0261	This protein binds to 23S rRNA in the presence of protein L20
MOO46_01600	COG0211	Belongs to the bacterial ribosomal protein bL27 family
MOO46_01605	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
MOO46_01610	COG1302	Protein conserved in bacteria
MOO46_01615	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MOO46_01620	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
MOO46_01625	COG1570	exodeoxyribonuclease VII activity
MOO46_01630	COG1722	exodeoxyribonuclease VII activity
MOO46_01640	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
MOO46_01645	COG0497	DNA recombination
MOO46_01650	COG0194	GDP metabolic process
MOO46_01655	COG1758	RNA polymerase activity
MOO46_01660	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
MOO46_01665	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
MOO46_01675	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MOO46_01675	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
MOO46_01680	COG0631	protein serine/threonine phosphatase activity
MOO46_01685	COG2815	serine threonine protein kinase
MOO46_01685	COG0515	serine threonine protein kinase
MOO46_01690	COG1162	GTPase activity
MOO46_01695	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
MOO46_01700	COG1564	THIamine pyrophosphokinase
MOO46_01705	COG2801	Transposase and inactivated derivatives
MOO46_01710	COG0227	Belongs to the bacterial ribosomal protein bL28 family
MOO46_01725	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
MOO46_01730	COG0416	fatty acid biosynthetic process
MOO46_01735	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MOO46_01740	COG0571	ribonuclease III activity
MOO46_01745	COG1196	nuclear chromosome segregation
MOO46_01750	COG0552	protein localization to endoplasmic reticulum
MOO46_01755	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
MOO46_01760	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MOO46_01780	COG0228	four-way junction DNA binding
MOO46_01790	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
MOO46_01795	COG0336	Belongs to the RNA methyltransferase TrmD family
MOO46_01800	COG0335	large ribosomal subunit rRNA binding
MOO46_01810	COG1942	4-Oxalocrotonate Tautomerase
MOO46_01815	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
MOO46_01820	COG0561	phosphatase activity
MOO46_01825	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
MOO46_01825	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
MOO46_01830	COG1304	FMN binding
MOO46_01845	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
MOO46_01865	COG2801	Transposase and inactivated derivatives
MOO46_01885	COG4474	Belongs to the UPF0398 family
MOO46_01890	COG3599	regulation of cell shape
MOO46_01900	COG0116	Belongs to the methyltransferase superfamily
MOO46_01905	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
MOO46_01920	COG2759	Belongs to the formate--tetrahydrofolate ligase family
MOO46_01925	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
MOO46_01930	COG0564	pseudouridine synthase activity
MOO46_01935	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
MOO46_01945	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MOO46_01950	COG1293	RNA-binding protein homologous to eukaryotic snRNP
MOO46_01955	COG1307	EDD domain protein, DegV family
MOO46_01965	COG0386	Belongs to the glutathione peroxidase family
MOO46_01975	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
MOO46_02000	COG2801	Transposase and inactivated derivatives
MOO46_02015	COG0151	Belongs to the GarS family
MOO46_02020	COG0138	bifunctional purine biosynthesis protein purh
MOO46_02025	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
MOO46_02030	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
MOO46_02035	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
MOO46_02040	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MOO46_02050	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
MOO46_02055	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
MOO46_02060	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
MOO46_02065	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
MOO46_02085	COG1227	inorganic diphosphatase activity
MOO46_02090	COG0583	DNA-binding transcription factor activity
MOO46_02095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
MOO46_02100	COG0187	DNA topoisomerase II activity
MOO46_02115	COG4974	Belongs to the 'phage' integrase family
MOO46_02120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
MOO46_02125	COG0758	DNA mediated transformation
MOO46_02140	COG4479	Belongs to the UPF0346 family
MOO46_02150	COG2755	lipolytic protein G-D-S-L family
MOO46_02155	COG1307	EDD domain protein, DegV family
MOO46_02160	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
MOO46_02165	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
MOO46_02170	COG0488	(ABC) transporter
MOO46_02185	COG0457	Tetratricopeptide repeat
MOO46_02195	COG1160	GTP binding
MOO46_02200	COG0539	negative regulation of cytoplasmic translation
MOO46_02205	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
MOO46_02210	COG1388	LysM domain
MOO46_02210	COG0791	NLP P60 protein
MOO46_02215	COG0514	ATP-dependent DNA helicase (RecQ)
MOO46_02225	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
MOO46_02230	COG1187	pseudouridine synthase activity
MOO46_02235	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
MOO46_02240	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
MOO46_02255	COG2996	Protein conserved in bacteria
MOO46_02265	COG0587	DNA-directed DNA polymerase activity
MOO46_02275	COG2801	Transposase and inactivated derivatives
MOO46_02280	COG0542	response to heat
MOO46_02290	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
MOO46_02295	COG2384	SAM-dependent methyltransferase
MOO46_02300	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
MOO46_02305	COG0358	DNA primase activity
MOO46_02310	COG0751	glycine-tRNA ligase activity
MOO46_02315	COG0752	glycyl-tRNA synthetase alpha subunit
MOO46_02320	COG1381	Involved in DNA repair and RecF pathway recombination
MOO46_02325	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
MOO46_02330	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
MOO46_02335	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
MOO46_02340	COG1702	phosphate starvation-inducible protein PhoH
MOO46_02345	COG1610	YqeY-like protein
MOO46_02350	COG0828	Belongs to the bacterial ribosomal protein bS21 family
MOO46_02355	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
MOO46_02360	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
MOO46_02365	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MOO46_02370	COG1682	transport, permease protein
MOO46_02375	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MOO46_02380	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
MOO46_02385	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
MOO46_02390	COG0124	histidyl-tRNA synthetase
MOO46_02395	COG3001	Fructosamine kinase
MOO46_02405	COG1490	D-aminoacyl-tRNA deacylase activity
MOO46_02410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
MOO46_02415	COG1385	rRNA (uridine-N3-)-methyltransferase activity
MOO46_02420	COG2264	protein methyltransferase activity
MOO46_02440	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
MOO46_02445	COG2233	PERMEase
MOO46_02450	COG0481	GTPase activity
MOO46_02455	COG0484	heat shock protein binding
MOO46_02470	COG1420	regulation of RNA biosynthetic process
MOO46_02475	COG0196	riboflavin kinase activity
MOO46_02485	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
MOO46_02490	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
MOO46_02500	COG2740	Nucleic-acid-binding protein implicated in transcription termination
MOO46_02505	COG0195	Participates in both transcription termination and antitermination
MOO46_02510	COG0779	Required for maturation of 30S ribosomal subunits
MOO46_02515	COG2176	DNA-directed DNA polymerase activity
MOO46_02520	COG0442	prolyl-tRNA aminoacylation
MOO46_02525	COG0750	zinc metalloprotease
MOO46_02530	COG4589	Belongs to the CDS family
MOO46_02535	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
MOO46_02545	COG0233	cytoplasmic translational termination
MOO46_02550	COG0528	UMP kinase activity
MOO46_02555	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
MOO46_02560	COG0052	Belongs to the universal ribosomal protein uS2 family
MOO46_02565	COG2827	Endonuclease containing a URI domain
MOO46_02570	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
MOO46_02575	COG0204	Acyl-transferase
MOO46_02580	COG3763	UPF0154 protein
MOO46_02585	COG4224	UPF0291 protein
MOO46_02590	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
MOO46_02600	COG3425	synthase
MOO46_02620	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MOO46_02625	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
MOO46_02625	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
MOO46_02630	COG1234	tRNA 3'-trailer cleavage
MOO46_02635	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MOO46_02640	COG0322	excinuclease ABC activity
MOO46_02655	COG0218	Necessary for normal cell division and for the maintenance of normal septation
MOO46_02660	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
MOO46_02665	COG0544	peptidyl-prolyl cis-trans isomerase activity
MOO46_02670	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
MOO46_02685	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
MOO46_02695	COG1466	dna polymerase III delta subunit
MOO46_02700	COG0658	competence protein
MOO46_02700	COG2333	competence protein COMEC
MOO46_02705	COG2131	deaminase
MOO46_02715	COG3480	Lon protease (S16) C-terminal proteolytic domain
MOO46_02720	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
MOO46_02725	COG0742	ribosomal rna small subunit methyltransferase
MOO46_02730	COG4471	UPF0298 protein
MOO46_02735	COG0772	Belongs to the SEDS family
MOO46_02740	COG1217	gtp-binding protein TYPA
MOO46_02745	COG0483	inositol monophosphate 1-phosphatase activity
MOO46_02760	COG0242	peptide deformylase activity
MOO46_02770	COG5503	Protein of unknown function (DUF1447)
MOO46_02780	COG1597	lipid kinase activity
MOO46_02795	COG0667	Aldo Keto reductase
MOO46_02800	COG4166	transmembrane transport
MOO46_02805	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MOO46_02810	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
MOO46_02825	COG0482	sulfurtransferase activity
MOO46_02835	COG1104	cysteine desulfurase activity
MOO46_02840	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
MOO46_02850	COG0494	nUDIX hydrolase
MOO46_02855	COG1278	Cold shock
MOO46_02860	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
MOO46_02865	COG3599	regulation of cell shape
MOO46_02870	COG2302	S4 RNA-binding domain
MOO46_02890	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
MOO46_02895	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
MOO46_02900	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
MOO46_02905	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
MOO46_02910	COG0768	penicillin binding
MOO46_02920	COG0275	rRNA processing
MOO46_02930	COG1674	ftsk spoiiie
MOO46_02940	COG0500	methyltransferase
MOO46_02945	COG0564	pseudouridine synthase activity
MOO46_02950	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
MOO46_02955	COG2357	RelA SpoT domain protein
MOO46_02970	COG4862	establishment of competence for transformation
MOO46_02975	COG1234	tRNA 3'-trailer cleavage
MOO46_03115	COG1368	sulfuric ester hydrolase activity
MOO46_03125	COG0438	transferase activity, transferring glycosyl groups
MOO46_03130	COG0438	transferase activity, transferring glycosyl groups
MOO46_03135	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
MOO46_03155	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
MOO46_03160	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
MOO46_03165	COG0628	permease
MOO46_03170	COG2137	regulation of response to DNA damage stimulus
MOO46_03175	COG0716	FMN binding
MOO46_03180	COG1295	ribonuclease BN
MOO46_03185	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
MOO46_03190	COG0463	Glycosyl transferase, family 2
MOO46_03195	COG2246	polysaccharide biosynthetic process
MOO46_03200	COG2610	gluconate transmembrane transporter activity
MOO46_03210	COG0745	RESPONSE REGULATOR receiver
MOO46_03215	COG0704	Plays a role in the regulation of phosphate uptake
MOO46_03220	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
MOO46_03230	COG0581	inorganic phosphate transmembrane transporter activity
MOO46_03235	COG0573	inorganic phosphate transmembrane transporter activity
MOO46_03255	COG3757	hydrolase, family 25
MOO46_03255	COG3409	Peptidoglycan-binding domain 1 protein
MOO46_03260	COG1070	Carbohydrate kinase
MOO46_03265	COG0531	amino acid
MOO46_03270	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MOO46_03275	COG1597	lipid kinase activity
MOO46_03280	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MOO46_03290	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
MOO46_03295	COG4851	CamS sex pheromone cAM373 precursor
MOO46_03300	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
MOO46_03315	COG1705	Flagellar rod assembly protein muramidase FlgJ
MOO46_03325	COG2801	Transposase and inactivated derivatives
MOO46_03340	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
MOO46_03345	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
MOO46_03350	COG0101	tRNA pseudouridine synthase activity
MOO46_03355	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
MOO46_03360	COG1122	ATPase activity
MOO46_03365	COG1122	ATPase activity
MOO46_03370	COG0203	ribosomal protein L17
MOO46_03375	COG0202	RNA polymerase activity
MOO46_03380	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
MOO46_03385	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MOO46_03395	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
MOO46_03400	COG0563	adenylate kinase activity
MOO46_03410	COG0200	Binds to the 23S rRNA
MOO46_03415	COG1841	ribosomal large subunit assembly
MOO46_03420	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
MOO46_03430	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
MOO46_03435	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
MOO46_03440	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
MOO46_03445	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MOO46_03450	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
MOO46_03455	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
MOO46_03470	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
MOO46_03475	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
MOO46_03480	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
MOO46_03485	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
MOO46_03490	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MOO46_03495	COG0089	rRNA binding
MOO46_03500	COG0088	Forms part of the polypeptide exit tunnel
MOO46_03505	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
MOO46_03510	COG0051	transcription antitermination factor activity, RNA binding
MOO46_03515	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
MOO46_03520	COG0049	tRNA binding
MOO46_03525	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
MOO46_03530	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
MOO46_03535	COG0085	RNA polymerase activity
MOO46_03540	COG0542	response to heat
MOO46_03545	COG4463	regulation of RNA biosynthetic process
MOO46_03590	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
MOO46_03595	COG1428	Deoxynucleoside kinase
MOO46_03600	COG0833	amino acid
MOO46_03615	COG2801	Transposase and inactivated derivatives
MOO46_03645	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MOO46_03645	COG1321	iron dependent repressor
MOO46_03675	COG0564	pseudouridine synthase activity
MOO46_03680	COG3338	carbonate dehydratase activity
MOO46_03685	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
MOO46_03700	COG1053	succinate dehydrogenase
MOO46_03750	COG0518	GMP synthase (glutamine-hydrolyzing) activity
MOO46_03750	COG0519	Catalyzes the synthesis of GMP from XMP
MOO46_03755	COG1072	(Pantothenic acid kinase))
MOO46_03760	COG3973	AAA domain
MOO46_03775	COG4608	Belongs to the ABC transporter superfamily
MOO46_03780	COG0444	Belongs to the ABC transporter superfamily
MOO46_03785	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
MOO46_03790	COG0601	transmembrane transport
MOO46_03795	COG4166	transmembrane transport
MOO46_03800	COG4166	transmembrane transport
MOO46_03805	COG4166	transmembrane transport
MOO46_03810	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
MOO46_03815	COG2855	membrane
MOO46_03825	COG0194	GDP metabolic process
MOO46_03835	COG2936	dipeptidyl-peptidase activity
MOO46_03840	COG2267	carboxylic ester hydrolase activity
MOO46_03860	COG0488	(ABC) transporter
MOO46_03870	COG0531	amino acid
MOO46_03880	COG4120	Belongs to the binding-protein-dependent transport system permease family
MOO46_03885	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
MOO46_03895	COG0477	Major facilitator Superfamily
MOO46_03920	COG1686	Belongs to the peptidase S11 family
MOO46_03930	COG1129	ABC transporter
MOO46_03955	COG2233	PERMEase
MOO46_03970	COG1307	EDD domain protein, DegV family
MOO46_03985	COG1199	ATP-dependent helicase activity
MOO46_03990	COG2706	6-phosphogluconolactonase activity
MOO46_03995	COG0833	amino acid
MOO46_04000	COG0833	amino acid
MOO46_04005	COG2040	homocysteine
MOO46_04015	COG0735	belongs to the Fur family
MOO46_04020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
MOO46_04025	COG0436	Aminotransferase
MOO46_04030	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
MOO46_04035	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
MOO46_04040	COG1473	amidohydrolase
MOO46_04045	COG2171	N-acyltransferase activity
MOO46_04055	COG0527	aspartate kinase activity
MOO46_04065	COG2814	Major facilitator Superfamily
MOO46_04070	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
MOO46_04075	COG0436	Aminotransferase
MOO46_04100	COG1506	peptidase
MOO46_04100	COG0823	Involved in the tonB-independent uptake of proteins
MOO46_04100	COG4946	Tricorn protease homolog
MOO46_04130	COG3590	peptidase
MOO46_04135	COG2814	Major facilitator Superfamily
MOO46_04145	COG0024	Methionine aminopeptidase
MOO46_04160	COG0110	maltose O-acetyltransferase activity
MOO46_04170	COG0351	phosphomethylpyrimidine kinase
MOO46_04190	COG2249	NAD(P)H dehydrogenase (quinone) activity
MOO46_04205	COG0601	transmembrane transport
MOO46_04210	COG4608	Belongs to the ABC transporter superfamily
MOO46_04220	COG1278	Cold shock
MOO46_04250	COG0697	spore germination
MOO46_04260	COG0531	amino acid
MOO46_04270	COG1033	growth of symbiont in host cell
MOO46_04270	COG2409	Drug exporters of the RND superfamily
MOO46_04280	COG0697	spore germination
MOO46_04285	COG0656	L-ascorbic acid biosynthetic process
MOO46_04290	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
MOO46_04295	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
MOO46_04300	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MOO46_04310	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
MOO46_04315	COG0825	malonyl-CoA metabolic process
MOO46_04320	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
MOO46_04325	COG0439	Biotin carboxylase
MOO46_04330	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
MOO46_04340	COG1028	Short-chain dehydrogenase reductase Sdr
MOO46_04345	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
MOO46_04350	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
MOO46_04355	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
MOO46_04360	COG4975	Glucose uptake
MOO46_04365	COG0778	Nitroreductase
MOO46_04370	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
MOO46_04395	COG0488	(ABC) transporter
MOO46_04400	COG0702	epimerase
MOO46_04440	COG1272	protein, Hemolysin III
MOO46_04450	COG1131	(ABC) transporter
MOO46_04465	COG1846	Transcriptional regulator
MOO46_04470	COG1113	amino acid transport
MOO46_04475	COG1113	amino acid transport
MOO46_04480	COG0531	amino acid
MOO46_04485	COG0446	pyridine nucleotide-disulphide oxidoreductase
MOO46_04520	COG1114	Component of the transport system for branched-chain amino acids
MOO46_04545	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
MOO46_04550	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
MOO46_04555	COG0516	GMP reductase activity
MOO46_04565	COG0167	dihydroorotate dehydrogenase activity
MOO46_04570	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
MOO46_04575	COG0505	Belongs to the CarA family
MOO46_04580	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
MOO46_04585	COG0540	Belongs to the ATCase OTCase family
MOO46_04590	COG1388	LysM domain
MOO46_04590	COG3942	CHAP domain
MOO46_04595	COG1388	LysM domain
MOO46_04595	COG3942	CHAP domain
MOO46_04605	COG1757	Na H antiporter
MOO46_04610	COG3118	belongs to the thioredoxin family
MOO46_04615	COG0861	Integral membrane protein TerC family
MOO46_04620	COG1705	Flagellar rod assembly protein muramidase FlgJ
MOO46_04640	COG1368	sulfuric ester hydrolase activity
MOO46_04650	COG0492	ferredoxin-NADP+ reductase activity
MOO46_04665	COG0561	phosphatase activity
MOO46_04670	COG1393	Belongs to the ArsC family
MOO46_04680	COG2801	Transposase and inactivated derivatives
MOO46_04685	COG1418	mRNA catabolic process
MOO46_04700	COG2801	Transposase and inactivated derivatives
MOO46_04705	COG0004	ammonium transporteR
MOO46_04725	COG0564	pseudouridine synthase activity
MOO46_04735	COG2188	Transcriptional regulator
MOO46_04740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
MOO46_04745	COG1418	mRNA catabolic process
MOO46_04755	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
MOO46_04760	COG0656	L-ascorbic acid biosynthetic process
MOO46_04770	COG4221	oxidoreductase activity
MOO46_04775	COG0789	Transcriptional regulator
MOO46_04800	COG2801	Transposase and inactivated derivatives
MOO46_04805	COG0584	glycerophosphoryl diester phosphodiesterase
MOO46_04815	COG3961	Belongs to the TPP enzyme family
MOO46_04825	COG1268	BioY protein
MOO46_04830	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
MOO46_04830	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
MOO46_04840	COG1063	alcohol dehydrogenase
MOO46_04845	COG1396	sequence-specific DNA binding
MOO46_04885	COG0577	efflux transmembrane transporter activity
MOO46_04890	COG1136	(ABC) transporter
MOO46_04895	COG2205	protein histidine kinase activity
MOO46_04930	COG2801	Transposase and inactivated derivatives
MOO46_04940	COG0071	Belongs to the small heat shock protein (HSP20) family
MOO46_04950	COG5002	protein histidine kinase activity
MOO46_04955	COG0745	RESPONSE REGULATOR receiver
MOO46_04965	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
MOO46_04970	COG0463	Glycosyl transferase, family 2
MOO46_04985	COG1253	flavin adenine dinucleotide binding
MOO46_05000	COG2814	Major facilitator Superfamily
MOO46_05010	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
MOO46_05015	COG2132	Multicopper oxidase
MOO46_05040	COG0183	Belongs to the thiolase family
MOO46_05055	COG1376	ErfK ybiS ycfS ynhG family protein
MOO46_05065	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MOO46_05085	COG1914	H( )-stimulated, divalent metal cation uptake system
MOO46_05090	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
MOO46_05095	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
MOO46_05100	COG0640	Transcriptional regulator
MOO46_05115	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
MOO46_05120	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
MOO46_05140	COG0745	RESPONSE REGULATOR receiver
MOO46_05160	COG2801	Transposase and inactivated derivatives
MOO46_05190	COG2801	Transposase and inactivated derivatives
MOO46_05220	COG3759	membrane
MOO46_05255	COG1328	CTP reductase activity
MOO46_05260	COG0602	queuosine metabolic process
MOO46_05265	COG0396	ATPase activity
MOO46_05270	COG0719	Fe-S assembly protein
MOO46_05275	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
MOO46_05285	COG0719	Fe-S assembly protein
MOO46_05305	COG4152	abc transporter atp-binding protein
MOO46_05320	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
MOO46_05325	COG1027	Aspartate ammonia-lyase
MOO46_05385	COG2814	Major facilitator Superfamily
MOO46_05390	COG0305	Participates in initiation and elongation during chromosome replication
MOO46_05395	COG0359	binds to the 23S rRNA
MOO46_05410	COG0629	single-stranded DNA binding
MOO46_05415	COG0360	Binds together with S18 to 16S ribosomal RNA
MOO46_05445	COG0187	DNA topoisomerase II activity
MOO46_05450	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
MOO46_05455	COG2501	S4 domain
MOO46_05475	COG1090	epimerase
MOO46_05500	COG0415	Belongs to the DNA photolyase family
MOO46_05535	COG1476	TRANSCRIPTIONal
MOO46_05615	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
MOO46_05625	COG0594	ribonuclease P activity
MOO46_05630	COG0706	membrane insertase activity
MOO46_05645	COG0445	tRNA wobble uridine modification
MOO46_05650	COG0110	maltose O-acetyltransferase activity
MOO46_05655	COG0656	L-ascorbic acid biosynthetic process
MOO46_05695	COG0765	amino acid transport
MOO46_05700	COG1126	abc transporter atp-binding protein
MOO46_05720	COG4166	transmembrane transport
MOO46_05730	COG0006	proline dipeptidase activity
MOO46_05770	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
MOO46_05775	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
MOO46_05780	COG0284	orotidine-5'-phosphate decarboxylase activity
MOO46_05785	COG2814	Major facilitator Superfamily
MOO46_05790	COG0531	amino acid
MOO46_05795	COG0583	DNA-binding transcription factor activity
MOO46_05800	COG4991	sh3 domain protein
MOO46_05800	COG3103	Sh3 type 3 domain protein
MOO46_05800	COG0860	N-Acetylmuramoyl-L-alanine amidase
MOO46_05805	COG1121	(ABC) transporter
MOO46_05810	COG1108	ABC-type Mn2 Zn2 transport systems permease components
MOO46_05830	COG0346	lactoylglutathione lyase activity
MOO46_05835	COG1063	alcohol dehydrogenase
MOO46_05840	COG1940	carbohydrate kinase activity
MOO46_05845	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MOO46_05850	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
MOO46_05860	COG2801	Transposase and inactivated derivatives
MOO46_05865	COG1335	isochorismatase
MOO46_05870	COG2252	PERMEase
MOO46_05885	COG2814	Major facilitator Superfamily
MOO46_05900	COG0667	Aldo Keto reductase
MOO46_05915	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
MOO46_05920	COG1074	ATP-dependent DNA helicase activity
MOO46_05940	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
MOO46_05950	COG0477	Major facilitator Superfamily
MOO46_05955	COG0446	pyridine nucleotide-disulphide oxidoreductase
MOO46_05990	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
MOO46_05995	COG1518	maintenance of DNA repeat elements
MOO46_06035	COG0028	Belongs to the TPP enzyme family
MOO46_06040	COG0519	Catalyzes the synthesis of GMP from XMP
MOO46_06065	COG1126	abc transporter atp-binding protein
MOO46_06070	COG0765	amino acid transport
MOO46_06115	COG0392	lysyltransferase activity
MOO46_06115	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
MOO46_06130	COG0583	DNA-binding transcription factor activity
MOO46_06140	COG0668	transmembrane transport
MOO46_06150	COG1122	ATPase activity
MOO46_06160	COG1309	transcriptional regulator
MOO46_06170	COG2801	Transposase and inactivated derivatives
MOO46_06180	COG0577	efflux transmembrane transporter activity
MOO46_06180	COG1136	(ABC) transporter
MOO46_06185	COG1309	transcriptional regulator
MOO46_06190	COG0481	GTPase activity
MOO46_06235	COG0248	Ppx GppA phosphatase
MOO46_06235	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
MOO46_06245	COG2801	Transposase and inactivated derivatives
MOO46_06270	COG0584	glycerophosphoryl diester phosphodiesterase
MOO46_06305	COG1309	transcriptional regulator
MOO46_06310	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
MOO46_06325	COG1940	carbohydrate kinase activity
MOO46_06330	COG1940	carbohydrate kinase activity
MOO46_06335	COG0166	Belongs to the GPI family
MOO46_06355	COG5263	repeat protein
MOO46_06355	COG0366	Alpha amylase catalytic
MOO46_06360	COG0308	aminopeptidase N
MOO46_06365	COG1686	Belongs to the peptidase S11 family
MOO46_06375	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
MOO46_06380	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
MOO46_06390	COG3639	organic phosphonate transmembrane transporter activity
MOO46_06395	COG0737	Belongs to the 5'-nucleotidase family
MOO46_06400	COG1695	Transcriptional regulator
MOO46_06415	COG1621	beta-fructofuranosidase activity
MOO46_06430	COG0702	epimerase
MOO46_06440	COG3152	Membrane
MOO46_06455	COG1247	-acetyltransferase
MOO46_06475	COG2801	Transposase and inactivated derivatives
MOO46_06510	COG0693	protein deglycase activity
MOO46_06515	COG3527	Alpha-acetolactate decarboxylase
MOO46_06540	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
MOO46_06545	COG0142	geranyltranstransferase activity
MOO46_06550	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
MOO46_06555	COG4988	ABC transporter
MOO46_06560	COG1294	oxidase, subunit
MOO46_06565	COG1271	oxidase subunit
MOO46_06570	COG1252	NADH dehydrogenase
MOO46_06580	COG1131	(ABC) transporter
MOO46_06610	COG0114	fumarate hydratase activity
MOO46_06650	COG1704	LemA family
MOO46_06655	COG1114	Component of the transport system for branched-chain amino acids
MOO46_06690	COG1686	Belongs to the peptidase S11 family
MOO46_06740	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
MOO46_06845	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
MOO46_06850	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
MOO46_06855	COG0357	Ribosomal RNA small subunit methyltransferase G
MOO46_06860	COG1192	Involved in chromosome partitioning
MOO46_06865	COG1475	DNA binding
MOO46_06870	COG4481	Protein conserved in bacteria
MOO46_06875	COG0012	GTP binding
MOO46_06885	COG0516	GMP reductase activity
MOO46_06885	COG0517	IMP dehydrogenase activity
MOO46_06905	COG2801	Transposase and inactivated derivatives
MOO46_06910	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
MOO46_06915	COG0628	permease
MOO46_06920	COG0588	phosphoglycerate mutase activity
MOO46_06940	COG2814	Major facilitator Superfamily
MOO46_06975	COG3973	AAA domain
MOO46_06985	COG0248	Ppx GppA phosphatase
MOO46_07000	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
MOO46_07005	COG1801	Protein of unknown function DUF72
MOO46_07010	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MOO46_07010	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
MOO46_07015	COG0084	hydrolase, TatD family'
MOO46_07020	COG1658	Required for correct processing of both the 5' and 3' ends of 5S rRNA precursor. Cleaves both sides of a double-stranded region yielding mature 5S rRNA in one step
MOO46_07025	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
MOO46_07030	COG4466	Protein conserved in bacteria
MOO46_07035	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
MOO46_07040	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
MOO46_07045	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
MOO46_07050	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
MOO46_07065	COG0561	phosphatase activity
MOO46_07070	COG1078	dGTPase activity
MOO46_07080	COG3343	RNA polymerase activity
MOO46_07085	COG0504	CTP synthase activity
MOO46_07095	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
MOO46_07105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
MOO46_07115	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
MOO46_07125	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
MOO46_07135	COG2337	Toxic component of a toxin-antitoxin (TA) module
MOO46_07145	COG0039	L-malate dehydrogenase activity
MOO46_07150	COG0193	aminoacyl-tRNA hydrolase activity
MOO46_07155	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
MOO46_07160	COG2244	polysaccharide biosynthetic process
MOO46_07165	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
MOO46_07175	COG1098	S1 RNA binding domain
MOO46_07180	COG0037	tRNA processing
MOO46_07195	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
MOO46_07200	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
MOO46_07205	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
MOO46_07245	COG3104	oligopeptide transport
MOO46_07260	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
MOO46_07265	COG2188	Transcriptional regulator
MOO46_07275	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
MOO46_07290	COG2183	response to ionizing radiation
MOO46_07295	COG3091	SprT-like family
MOO46_07300	COG0083	homoserine kinase activity
MOO46_07395	COG3617	BRO family, N-terminal domain
MOO46_07590	COG3953	SLT domain
MOO46_07590	COG5280	Phage tail tape measure protein TP901
MOO46_07625	COG0582	viral genome integration into host DNA
MOO46_07740	COG3299	homolog of phage Mu protein gp47
MOO46_07790	COG1192	Involved in chromosome partitioning