locus-tag	class	description
LDX55_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LDX55_00010	COG0592	DNA-directed DNA polymerase activity
LDX55_00020	COG2501	S4 domain
LDX55_00025	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
LDX55_00030	COG0187	DNA topoisomerase II activity
LDX55_00050	COG0360	Binds together with S18 to 16S ribosomal RNA
LDX55_00055	COG0629	single-stranded DNA binding
LDX55_00070	COG0359	binds to the 23S rRNA
LDX55_00075	COG0305	Participates in initiation and elongation during chromosome replication
LDX55_00090	COG2801	Transposase and inactivated derivatives
LDX55_00100	COG1695	Transcriptional regulator
LDX55_00105	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LDX55_00110	COG4166	transmembrane transport
LDX55_00115	COG0436	Aminotransferase
LDX55_00125	COG1846	Transcriptional regulator
LDX55_00140	COG1027	Aspartate ammonia-lyase
LDX55_00145	COG0719	Fe-S assembly protein
LDX55_00155	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LDX55_00160	COG0719	Fe-S assembly protein
LDX55_00165	COG0396	ATPase activity
LDX55_00175	COG1328	CTP reductase activity
LDX55_00185	COG2801	Transposase and inactivated derivatives
LDX55_00205	COG1028	Short-chain dehydrogenase reductase Sdr
LDX55_00210	COG2153	protein acetylation
LDX55_00235	COG0745	RESPONSE REGULATOR receiver
LDX55_00240	COG5002	protein histidine kinase activity
LDX55_00255	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LDX55_00260	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LDX55_00275	COG2801	Transposase and inactivated derivatives
LDX55_00300	COG1914	H( )-stimulated, divalent metal cation uptake system
LDX55_00305	COG0589	response to stress
LDX55_00315	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDX55_00320	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LDX55_00335	COG2211	Major facilitator Superfamily
LDX55_00345	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LDX55_00355	COG0352	thiamine-phosphate diphosphorylase activity
LDX55_00360	COG0351	phosphomethylpyrimidine kinase
LDX55_00365	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LDX55_00375	COG1376	ErfK ybiS ycfS ynhG family protein
LDX55_00390	COG0183	Belongs to the thiolase family
LDX55_00415	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LDX55_00420	COG0505	Belongs to the CarA family
LDX55_00425	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LDX55_00435	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LDX55_00440	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LDX55_00445	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
LDX55_00450	COG2132	Multicopper oxidase
LDX55_00455	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
LDX55_00465	COG2814	Major facilitator Superfamily
LDX55_00475	COG1253	flavin adenine dinucleotide binding
LDX55_00500	COG0463	Glycosyl transferase, family 2
LDX55_00505	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
LDX55_00515	COG0745	RESPONSE REGULATOR receiver
LDX55_00520	COG5002	protein histidine kinase activity
LDX55_00530	COG0071	Belongs to the small heat shock protein (HSP20) family
LDX55_00535	COG0071	Belongs to the small heat shock protein (HSP20) family
LDX55_00620	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LDX55_00630	COG0789	Transcriptional regulator
LDX55_00665	COG2801	Transposase and inactivated derivatives
LDX55_00680	COG1940	carbohydrate kinase activity
LDX55_00690	COG1695	Transcriptional regulator
LDX55_00730	COG2801	Transposase and inactivated derivatives
LDX55_00735	COG1063	alcohol dehydrogenase
LDX55_00740	COG0531	amino acid
LDX55_00780	COG1131	(ABC) transporter
LDX55_00790	COG0656	L-ascorbic acid biosynthetic process
LDX55_00795	COG0789	Transcriptional regulator
LDX55_00815	COG0789	Transcriptional regulator
LDX55_00825	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
LDX55_00835	COG1268	BioY protein
LDX55_00850	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LDX55_00860	COG0656	L-ascorbic acid biosynthetic process
LDX55_00865	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
LDX55_00875	COG1418	mRNA catabolic process
LDX55_00880	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
LDX55_00895	COG2188	Transcriptional regulator
LDX55_00905	COG0564	pseudouridine synthase activity
LDX55_00925	COG0004	ammonium transporteR
LDX55_00940	COG1418	mRNA catabolic process
LDX55_00950	COG1393	Belongs to the ArsC family
LDX55_00955	COG0561	phosphatase activity
LDX55_00970	COG0492	ferredoxin-NADP+ reductase activity
LDX55_00980	COG1368	sulfuric ester hydrolase activity
LDX55_01005	COG1705	Flagellar rod assembly protein muramidase FlgJ
LDX55_01010	COG0861	Integral membrane protein TerC family
LDX55_01015	COG3118	belongs to the thioredoxin family
LDX55_01020	COG1757	Na H antiporter
LDX55_01030	COG3584	3D domain protein
LDX55_01030	COG1388	LysM domain
LDX55_01040	COG0540	Belongs to the ATCase OTCase family
LDX55_01050	COG0505	Belongs to the CarA family
LDX55_01055	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
LDX55_01060	COG0167	dihydroorotate dehydrogenase activity
LDX55_01065	COG3764	Sortase (surface protein transpeptidase)
LDX55_01070	COG0516	GMP reductase activity
LDX55_01075	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LDX55_01080	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LDX55_01150	COG0438	transferase activity, transferring glycosyl groups
LDX55_01170	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LDX55_01180	COG2801	Transposase and inactivated derivatives
LDX55_01220	COG0583	DNA-binding transcription factor activity
LDX55_01260	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
LDX55_01265	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
LDX55_01275	COG0357	Ribosomal RNA small subunit methyltransferase G
LDX55_01280	COG1192	Involved in chromosome partitioning
LDX55_01285	COG1475	DNA binding
LDX55_01290	COG4481	Protein conserved in bacteria
LDX55_01295	COG0012	GTP binding
LDX55_01305	COG0516	GMP reductase activity
LDX55_01305	COG0517	IMP dehydrogenase activity
LDX55_01315	COG5002	protein histidine kinase activity
LDX55_01320	COG1686	Belongs to the peptidase S11 family
LDX55_01340	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
LDX55_01345	COG0628	permease
LDX55_01350	COG0588	phosphoglycerate mutase activity
LDX55_01375	COG2814	Major facilitator Superfamily
LDX55_01385	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LDX55_01415	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LDX55_01420	COG3973	AAA domain
LDX55_01430	COG0248	Ppx GppA phosphatase
LDX55_01445	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
LDX55_01450	COG1801	Protein of unknown function DUF72
LDX55_01455	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDX55_01455	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDX55_01460	COG0084	hydrolase, TatD family'
LDX55_01470	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LDX55_01475	COG4466	Protein conserved in bacteria
LDX55_01480	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LDX55_01485	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LDX55_01490	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LDX55_01495	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LDX55_01505	COG0561	phosphatase activity
LDX55_01510	COG1078	dGTPase activity
LDX55_01520	COG3343	RNA polymerase activity
LDX55_01525	COG0504	CTP synthase activity
LDX55_01530	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LDX55_01535	COG0254	rRNA binding
LDX55_01540	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
LDX55_01545	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LDX55_01560	COG2801	Transposase and inactivated derivatives
LDX55_01565	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
LDX55_01570	COG2337	Toxic component of a toxin-antitoxin (TA) module
LDX55_01580	COG0039	L-malate dehydrogenase activity
LDX55_01585	COG0193	aminoacyl-tRNA hydrolase activity
LDX55_01590	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LDX55_01595	COG2244	polysaccharide biosynthetic process
LDX55_01600	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
LDX55_01610	COG1098	S1 RNA binding domain
LDX55_01615	COG0037	tRNA processing
LDX55_01630	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LDX55_01635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
LDX55_01640	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
LDX55_01680	COG3104	oligopeptide transport
LDX55_01695	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
LDX55_01700	COG2188	Transcriptional regulator
LDX55_01710	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LDX55_01725	COG2183	response to ionizing radiation
LDX55_01730	COG3091	SprT-like family
LDX55_01735	COG0083	homoserine kinase activity
LDX55_01755	COG1316	TRANSCRIPTIONal
LDX55_01760	COG0697	spore germination
LDX55_01765	COG0588	phosphoglycerate mutase activity
LDX55_01775	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LDX55_01780	COG0756	dUTP diphosphatase activity
LDX55_01785	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
LDX55_01790	COG4956	integral membrane protein (PIN domain superfamily)
LDX55_01795	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LDX55_01800	COG0215	cysteine-tRNA ligase activity
LDX55_01805	COG1939	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)
LDX55_01810	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LDX55_01815	COG3688	RNA-binding protein containing a PIN domain
LDX55_01825	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LDX55_01830	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LDX55_01835	COG0250	Participates in transcription elongation, termination and antitermination
LDX55_01840	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LDX55_01845	COG0081	regulation of translation
LDX55_01850	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LDX55_01855	COG0222	ribosome binding
LDX55_01860	COG0392	lysyltransferase activity
LDX55_01860	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
LDX55_01870	COG2801	Transposase and inactivated derivatives
LDX55_01875	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDX55_01880	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LDX55_01885	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LDX55_01890	COG2813	Specifically methylates the guanine in position
LDX55_01905	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LDX55_01925	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LDX55_01930	COG3870	Protein conserved in bacteria
LDX55_01935	COG0470	DNA polymerase III
LDX55_01940	COG4467	Involved in initiation control of chromosome replication
LDX55_01945	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LDX55_01955	COG1214	PFAM Peptidase M22, glycoprotease
LDX55_01965	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LDX55_01970	COG0488	(ABC) transporter
LDX55_01975	COG2344	Modulates transcription in response to changes in cellular NADH NAD( ) redox state
LDX55_01980	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LDX55_01985	COG0459	protein refolding
LDX55_01990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LDX55_01995	COG1739	Uncharacterized protein family UPF0029
LDX55_02000	COG4098	Superfamily II DNA RNA helicase required for DNA uptake (late competence protein)
LDX55_02010	COG0653	protein targeting
LDX55_02020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LDX55_02025	COG1983	PspC domain protein
LDX55_02030	COG1950	PFAM Membrane protein of
LDX55_02035	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
LDX55_02040	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LDX55_02045	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LDX55_02055	COG0492	ferredoxin-NADP+ reductase activity
LDX55_02060	COG0556	nucleotide-excision repair
LDX55_02065	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LDX55_02070	COG0391	Required for morphogenesis under gluconeogenic growth conditions
LDX55_02075	COG1481	regulation of sporulation
LDX55_02080	COG0740	serine-type endopeptidase activity
LDX55_02100	COG0149	triose-phosphate isomerase activity
LDX55_02105	COG0148	phosphopyruvate hydratase activity
LDX55_02115	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LDX55_02120	COG0557	exoribonuclease II activity
LDX55_02130	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
LDX55_02135	COG0280	phosphate acetyltransferase
LDX55_02140	COG0802	atpase or kinase
LDX55_02150	COG2176	DNA-directed DNA polymerase activity
LDX55_02155	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LDX55_02160	COG0025	NhaP-type Na H and K H
LDX55_02175	COG4856	YbbR-like protein
LDX55_02180	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LDX55_02185	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LDX55_02205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
LDX55_02210	COG2801	Transposase and inactivated derivatives
LDX55_02220	COG3158	transport of potassium into the cell
LDX55_02240	COG0477	Major facilitator Superfamily
LDX55_02250	COG4975	Glucose uptake
LDX55_02265	COG0017	Asparaginyl-tRNA synthetase
LDX55_02270	COG1942	4-Oxalocrotonate Tautomerase
LDX55_02275	COG1063	alcohol dehydrogenase
LDX55_02290	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
LDX55_02295	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LDX55_02320	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
LDX55_02335	COG0697	spore germination
LDX55_02370	COG3759	membrane
LDX55_02375	COG1335	isochorismatase
LDX55_02395	COG1132	(ABC) transporter
LDX55_02400	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
LDX55_02405	COG3442	glutamine amidotransferase
LDX55_02410	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
LDX55_02415	COG1435	thymidine kinase activity
LDX55_02425	COG2890	protein-(glutamine-N5) methyltransferase activity
LDX55_02430	COG0009	L-threonylcarbamoyladenylate synthase
LDX55_02435	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LDX55_02440	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
LDX55_02445	COG0356	it plays a direct role in the translocation of protons across the membrane
LDX55_02450	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LDX55_02455	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LDX55_02460	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LDX55_02465	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LDX55_02470	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LDX55_02475	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LDX55_02480	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LDX55_02490	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LDX55_02495	COG1077	Cell shape determining protein MreB Mrl
LDX55_02500	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LDX55_02510	COG0772	Belongs to the SEDS family
LDX55_02515	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LDX55_02520	COG2011	ABC-type metal ion transport system permease component
LDX55_02525	COG1464	Belongs to the NlpA lipoprotein family
LDX55_02530	COG2188	Transcriptional regulator
LDX55_02535	COG1131	(ABC) transporter
LDX55_02545	COG1181	Belongs to the D-alanine--D-alanine ligase family
LDX55_02550	COG0519	Catalyzes the synthesis of GMP from XMP
LDX55_02560	COG0589	response to stress
LDX55_02570	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LDX55_02580	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LDX55_02585	COG1956	GAF domain-containing protein
LDX55_02590	COG4477	modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization
LDX55_02595	COG1104	cysteine desulfurase activity
LDX55_02600	COG0301	tRNA thio-modification
LDX55_02610	COG0525	valine-tRNA ligase activity
LDX55_02615	COG0285	dihydrofolate synthase activity
LDX55_02620	COG1077	Cell shape determining protein MreB Mrl
LDX55_02635	COG0850	regulation of cytokinetic process
LDX55_02640	COG2894	cell division
LDX55_02645	COG0765	amino acid transport
LDX55_02650	COG1126	abc transporter atp-binding protein
LDX55_02655	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDX55_02665	COG0612	Peptidase, M16
LDX55_02670	COG1426	Protein conserved in bacteria
LDX55_02675	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LDX55_02680	COG1058	Belongs to the CinA family
LDX55_02680	COG1546	Belongs to the CinA family
LDX55_02685	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LDX55_02695	COG1692	metallophosphoesterase
LDX55_02700	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LDX55_02705	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LDX55_02715	COG2255	four-way junction helicase activity
LDX55_02720	COG1862	Preprotein translocase
LDX55_02725	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
LDX55_02730	COG0513	Belongs to the DEAD box helicase family
LDX55_02735	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LDX55_02740	COG4472	Bacterial protein of unknown function (DUF965)
LDX55_02750	COG3906	Belongs to the UPF0473 family
LDX55_02765	COG1193	negative regulation of DNA recombination
LDX55_02770	COG3118	belongs to the thioredoxin family
LDX55_02775	COG1719	4-vinyl reductase, 4VR
LDX55_02785	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LDX55_02800	COG1609	Transcriptional regulator
LDX55_02805	COG0217	transcriptional regulatory protein
LDX55_02810	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
LDX55_02815	COG1459	type II secretion system
LDX55_02820	COG4537	Required for transformation and DNA binding
LDX55_02835	COG0827	DNA restriction-modification system
LDX55_02845	COG1113	amino acid transport
LDX55_02855	COG0737	Belongs to the 5'-nucleotidase family
LDX55_02860	COG4470	Protein conserved in bacteria
LDX55_02865	COG0647	UMP catabolic process
LDX55_02875	COG0586	Pfam SNARE associated Golgi protein
LDX55_02880	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
LDX55_02960	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LDX55_02965	COG0477	Major facilitator Superfamily
LDX55_02970	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
LDX55_02975	COG0495	leucyl-tRNA aminoacylation
LDX55_02980	COG2244	polysaccharide biosynthetic process
LDX55_02990	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
LDX55_03000	COG1428	Deoxynucleoside kinase
LDX55_03015	COG2801	Transposase and inactivated derivatives
LDX55_03030	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
LDX55_03035	COG0367	asparagine synthase
LDX55_03050	COG1794	racemase activity, acting on amino acids and derivatives
LDX55_03075	COG0018	arginyl-trna synthetase
LDX55_03080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
LDX55_03085	COG0420	3'-5' exonuclease activity
LDX55_03090	COG4717	serine-type aminopeptidase activity
LDX55_03095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LDX55_03105	COG0537	adenosine 5'-monophosphoramidase activity
LDX55_03110	COG1131	(ABC) transporter
LDX55_03120	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LDX55_03125	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LDX55_03130	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDX55_03135	COG1674	ftsk spoiiie
LDX55_03140	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LDX55_03150	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LDX55_03150	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LDX55_03155	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LDX55_03160	COG0237	dephospho-CoA kinase activity
LDX55_03165	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LDX55_03170	COG3611	Membrane attachment protein
LDX55_03175	COG1484	DNA-dependent DNA replication
LDX55_03180	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LDX55_03185	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LDX55_03190	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LDX55_03195	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LDX55_03205	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
LDX55_03210	COG1534	Rna-binding protein
LDX55_03215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LDX55_03220	COG1713	HD superfamily hydrolase involved in NAD metabolism
LDX55_03225	COG0799	negative regulation of ribosome biogenesis
LDX55_03230	COG2226	methyltransferase
LDX55_03235	COG1323	Belongs to the UPF0348 family
LDX55_03245	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LDX55_03250	COG0745	RESPONSE REGULATOR receiver
LDX55_03255	COG5002	protein histidine kinase activity
LDX55_03265	COG0187	DNA topoisomerase II activity
LDX55_03275	COG0583	DNA-binding transcription factor activity
LDX55_03280	COG1227	inorganic diphosphatase activity
LDX55_03310	COG1293	RNA-binding protein homologous to eukaryotic snRNP
LDX55_03315	COG1307	EDD domain protein, DegV family
LDX55_03330	COG0386	Belongs to the glutathione peroxidase family
LDX55_03360	COG0505	Belongs to the CarA family
LDX55_03365	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
LDX55_03370	COG0564	pseudouridine synthase activity
LDX55_03375	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LDX55_03390	COG0328	RNA-DNA hybrid ribonuclease activity
LDX55_03395	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LDX55_03400	COG0116	Belongs to the methyltransferase superfamily
LDX55_03415	COG4474	Belongs to the UPF0398 family
LDX55_03420	COG3331	DNA recombination
LDX55_03445	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
LDX55_03460	COG1304	FMN binding
LDX55_03480	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LDX55_03480	COG3270	Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA
LDX55_03485	COG0561	phosphatase activity
LDX55_03495	COG1942	4-Oxalocrotonate Tautomerase
LDX55_03505	COG0335	large ribosomal subunit rRNA binding
LDX55_03510	COG0336	Belongs to the RNA methyltransferase TrmD family
LDX55_03515	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LDX55_03525	COG0228	four-way junction DNA binding
LDX55_03545	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LDX55_03550	COG2739	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein
LDX55_03555	COG0552	protein localization to endoplasmic reticulum
LDX55_03560	COG1196	nuclear chromosome segregation
LDX55_03565	COG0571	ribonuclease III activity
LDX55_03570	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LDX55_03575	COG0416	fatty acid biosynthetic process
LDX55_03580	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LDX55_03585	COG1461	Dihydroxyacetone kinase
LDX55_03590	COG1302	Protein conserved in bacteria
LDX55_03595	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LDX55_03600	COG1564	THIamine pyrophosphokinase
LDX55_03605	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
LDX55_03610	COG1162	GTPase activity
LDX55_03620	COG0631	protein serine/threonine phosphatase activity
LDX55_03625	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LDX55_03625	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LDX55_03630	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LDX55_03635	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
LDX55_03640	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LDX55_03650	COG0194	GDP metabolic process
LDX55_03655	COG0497	DNA recombination
LDX55_03660	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
LDX55_03665	COG0142	geranyltranstransferase activity
LDX55_03670	COG1722	exodeoxyribonuclease VII activity
LDX55_03675	COG1570	exodeoxyribonuclease VII activity
LDX55_03680	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LDX55_03685	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LDX55_03690	COG1302	Protein conserved in bacteria
LDX55_03695	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LDX55_03700	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LDX55_03710	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LDX55_03725	COG2801	Transposase and inactivated derivatives
LDX55_03740	COG0789	Transcriptional regulator
LDX55_03760	COG1940	carbohydrate kinase activity
LDX55_03775	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LDX55_03780	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LDX55_03785	COG0768	penicillin binding
LDX55_03795	COG2801	Transposase and inactivated derivatives
LDX55_03805	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LDX55_03810	COG0572	uridine kinase
LDX55_03815	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LDX55_03820	COG0072	phenylalanine-tRNA ligase activity
LDX55_03820	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LDX55_03825	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LDX55_03830	COG1733	regulation of RNA biosynthetic process
LDX55_03840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LDX55_03845	COG1254	Belongs to the acylphosphatase family
LDX55_03850	COG0706	membrane insertase activity
LDX55_03865	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LDX55_03870	COG0758	DNA mediated transformation
LDX55_03895	COG2755	lipolytic protein G-D-S-L family
LDX55_03905	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LDX55_03910	COG0488	(ABC) transporter
LDX55_03935	COG1160	GTP binding
LDX55_03940	COG0539	negative regulation of cytoplasmic translation
LDX55_03945	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LDX55_03955	COG0514	ATP-dependent DNA helicase (RecQ)
LDX55_03965	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
LDX55_03970	COG1187	pseudouridine synthase activity
LDX55_03975	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
LDX55_03985	COG0456	acetyltransferase
LDX55_03995	COG2996	Protein conserved in bacteria
LDX55_04005	COG0587	DNA-directed DNA polymerase activity
LDX55_04015	COG0542	response to heat
LDX55_04025	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
LDX55_04030	COG2384	SAM-dependent methyltransferase
LDX55_04035	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LDX55_04040	COG0358	DNA primase activity
LDX55_04045	COG0751	glycine-tRNA ligase activity
LDX55_04050	COG0752	glycyl-tRNA synthetase alpha subunit
LDX55_04055	COG1381	Involved in DNA repair and RecF pathway recombination
LDX55_04060	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
LDX55_04065	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
LDX55_04070	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LDX55_04075	COG1702	phosphate starvation-inducible protein PhoH
LDX55_04080	COG1610	YqeY-like protein
LDX55_04085	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LDX55_04090	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LDX55_04095	COG0648	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin
LDX55_04100	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LDX55_04105	COG1682	transport, permease protein
LDX55_04110	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LDX55_04115	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
LDX55_04120	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LDX55_04125	COG0124	histidyl-tRNA synthetase
LDX55_04130	COG3001	Fructosamine kinase
LDX55_04135	COG0546	phosphoglycolate phosphatase activity
LDX55_04140	COG1490	D-aminoacyl-tRNA deacylase activity
LDX55_04145	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
LDX55_04150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
LDX55_04155	COG2264	protein methyltransferase activity
LDX55_04170	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
LDX55_04180	COG0481	GTPase activity
LDX55_04185	COG0484	heat shock protein binding
LDX55_04200	COG1420	regulation of RNA biosynthetic process
LDX55_04205	COG0196	riboflavin kinase activity
LDX55_04210	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LDX55_04215	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LDX55_04220	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LDX55_04230	COG2740	Nucleic-acid-binding protein implicated in transcription termination
LDX55_04235	COG0195	Participates in both transcription termination and antitermination
LDX55_04240	COG0779	Required for maturation of 30S ribosomal subunits
LDX55_04245	COG2176	DNA-directed DNA polymerase activity
LDX55_04250	COG0442	prolyl-tRNA aminoacylation
LDX55_04255	COG0750	zinc metalloprotease
LDX55_04260	COG4589	Belongs to the CDS family
LDX55_04265	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
LDX55_04275	COG0233	cytoplasmic translational termination
LDX55_04280	COG0528	UMP kinase activity
LDX55_04285	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LDX55_04290	COG0052	Belongs to the universal ribosomal protein uS2 family
LDX55_04295	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDX55_04300	COG2827	Endonuclease containing a URI domain
LDX55_04305	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
LDX55_04310	COG0204	Acyl-transferase
LDX55_04320	COG2801	Transposase and inactivated derivatives
LDX55_04325	COG3763	UPF0154 protein
LDX55_04330	COG4224	UPF0291 protein
LDX55_04335	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LDX55_04345	COG3425	synthase
LDX55_04365	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LDX55_04370	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LDX55_04370	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
LDX55_04375	COG1234	tRNA 3'-trailer cleavage
LDX55_04380	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LDX55_04385	COG0322	excinuclease ABC activity
LDX55_04400	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LDX55_04410	COG2801	Transposase and inactivated derivatives
LDX55_04415	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LDX55_04420	COG0544	peptidyl-prolyl cis-trans isomerase activity
LDX55_04425	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LDX55_04440	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LDX55_04450	COG1466	dna polymerase III delta subunit
LDX55_04455	COG0658	competence protein
LDX55_04455	COG2333	competence protein COMEC
LDX55_04460	COG2131	deaminase
LDX55_04470	COG3480	Lon protease (S16) C-terminal proteolytic domain
LDX55_04475	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LDX55_04480	COG0742	ribosomal rna small subunit methyltransferase
LDX55_04485	COG4471	UPF0298 protein
LDX55_04495	COG1217	gtp-binding protein TYPA
LDX55_04500	COG0483	inositol monophosphate 1-phosphatase activity
LDX55_04510	COG0039	L-malate dehydrogenase activity
LDX55_04515	COG0242	peptide deformylase activity
LDX55_04525	COG5503	Protein of unknown function (DUF1447)
LDX55_04535	COG1597	lipid kinase activity
LDX55_04545	COG0667	Aldo Keto reductase
LDX55_04550	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
LDX55_04555	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LDX55_04570	COG0482	sulfurtransferase activity
LDX55_04580	COG1104	cysteine desulfurase activity
LDX55_04585	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
LDX55_04595	COG0494	nUDIX hydrolase
LDX55_04600	COG1278	Cold shock
LDX55_04605	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LDX55_04610	COG3599	regulation of cell shape
LDX55_04620	COG1799	cell septum assembly
LDX55_04635	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
LDX55_04640	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LDX55_04650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LDX55_04655	COG0768	penicillin binding
LDX55_04665	COG0275	rRNA processing
LDX55_04685	COG1674	ftsk spoiiie
LDX55_04695	COG0500	methyltransferase
LDX55_04700	COG0564	pseudouridine synthase activity
LDX55_04705	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
LDX55_04710	COG2357	RelA SpoT domain protein
LDX55_04720	COG1164	Oligoendopeptidase f
LDX55_04730	COG4862	establishment of competence for transformation
LDX55_04735	COG1234	tRNA 3'-trailer cleavage
LDX55_04750	COG2801	Transposase and inactivated derivatives
LDX55_04895	COG1368	sulfuric ester hydrolase activity
LDX55_04905	COG0438	transferase activity, transferring glycosyl groups
LDX55_04910	COG0438	transferase activity, transferring glycosyl groups
LDX55_04925	COG0542	response to heat
LDX55_04935	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LDX55_04940	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
LDX55_04945	COG0628	permease
LDX55_04950	COG2137	regulation of response to DNA damage stimulus
LDX55_04955	COG0716	FMN binding
LDX55_04960	COG1295	ribonuclease BN
LDX55_04965	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
LDX55_04970	COG0463	Glycosyl transferase, family 2
LDX55_04975	COG2246	polysaccharide biosynthetic process
LDX55_04980	COG2610	gluconate transmembrane transporter activity
LDX55_04995	COG0704	Plays a role in the regulation of phosphate uptake
LDX55_05000	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LDX55_05010	COG0581	inorganic phosphate transmembrane transporter activity
LDX55_05015	COG0573	inorganic phosphate transmembrane transporter activity
LDX55_05040	COG3409	Peptidoglycan-binding domain 1 protein
LDX55_05040	COG3757	hydrolase, family 25
LDX55_05045	COG1070	Carbohydrate kinase
LDX55_05050	COG0531	amino acid
LDX55_05065	COG2801	Transposase and inactivated derivatives
LDX55_05085	COG2801	Transposase and inactivated derivatives
LDX55_05090	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
LDX55_05095	COG1597	lipid kinase activity
LDX55_05100	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LDX55_05105	COG0154	amidase activity
LDX55_05110	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LDX55_05115	COG4851	CamS sex pheromone cAM373 precursor
LDX55_05120	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LDX55_05130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
LDX55_05135	COG1705	Flagellar rod assembly protein muramidase FlgJ
LDX55_05145	COG4684	Psort location CytoplasmicMembrane, score
LDX55_05150	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LDX55_05155	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LDX55_05160	COG0101	tRNA pseudouridine synthase activity
LDX55_05165	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
LDX55_05170	COG1122	ATPase activity
LDX55_05180	COG0203	ribosomal protein L17
LDX55_05185	COG0202	RNA polymerase activity
LDX55_05190	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LDX55_05195	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LDX55_05205	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LDX55_05210	COG0563	adenylate kinase activity
LDX55_05220	COG0200	Binds to the 23S rRNA
LDX55_05225	COG1841	ribosomal large subunit assembly
LDX55_05230	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LDX55_05240	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LDX55_05245	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LDX55_05250	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LDX55_05255	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LDX55_05260	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LDX55_05265	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LDX55_05280	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LDX55_05285	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LDX55_05290	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LDX55_05300	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LDX55_05305	COG0089	rRNA binding
LDX55_05310	COG0088	Forms part of the polypeptide exit tunnel
LDX55_05315	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LDX55_05320	COG0051	transcription antitermination factor activity, RNA binding
LDX55_05325	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LDX55_05330	COG0049	tRNA binding
LDX55_05335	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LDX55_05350	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LDX55_05355	COG0085	RNA polymerase activity
LDX55_05360	COG0542	response to heat
LDX55_05365	COG4463	regulation of RNA biosynthetic process
LDX55_05410	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LDX55_05415	COG1428	Deoxynucleoside kinase
LDX55_05420	COG0833	amino acid
LDX55_05440	COG0730	response to heat
LDX55_05490	COG0564	pseudouridine synthase activity
LDX55_05495	COG3338	carbonate dehydratase activity
LDX55_05510	COG1064	alcohol dehydrogenase
LDX55_05515	COG0697	spore germination
LDX55_05520	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LDX55_05525	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LDX55_05530	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LDX55_05530	COG0519	Catalyzes the synthesis of GMP from XMP
LDX55_05535	COG1072	(Pantothenic acid kinase))
LDX55_05540	COG3973	AAA domain
LDX55_05545	COG0406	alpha-ribazole phosphatase activity
LDX55_05550	COG4608	Belongs to the ABC transporter superfamily
LDX55_05555	COG0444	Belongs to the ABC transporter superfamily
LDX55_05560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LDX55_05565	COG0601	transmembrane transport
LDX55_05570	COG4166	transmembrane transport
LDX55_05575	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LDX55_05590	COG0194	GDP metabolic process
LDX55_05600	COG2936	dipeptidyl-peptidase activity
LDX55_05605	COG2267	carboxylic ester hydrolase activity
LDX55_05615	COG0488	(ABC) transporter
LDX55_05625	COG0531	amino acid
LDX55_05635	COG4120	Belongs to the binding-protein-dependent transport system permease family
LDX55_05640	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LDX55_05645	COG2084	Dehydrogenase
LDX55_05670	COG0583	DNA-binding transcription factor activity
LDX55_05675	COG0531	amino acid
LDX55_05685	COG1686	Belongs to the peptidase S11 family
LDX55_05690	COG4721	ABC-type cobalt transport system, permease component
LDX55_05695	COG1122	ATPase activity
LDX55_05720	COG2233	PERMEase
LDX55_05745	COG1307	EDD domain protein, DegV family
LDX55_05755	COG2801	Transposase and inactivated derivatives
LDX55_05770	COG2706	6-phosphogluconolactonase activity
LDX55_05775	COG0833	amino acid
LDX55_05780	COG2040	homocysteine
LDX55_05790	COG0735	belongs to the Fur family
LDX55_05795	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LDX55_05800	COG0436	Aminotransferase
LDX55_05805	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LDX55_05810	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LDX55_05815	COG1473	amidohydrolase
LDX55_05820	COG2171	N-acyltransferase activity
LDX55_05825	COG0019	diaminopimelate decarboxylase activity
LDX55_05830	COG0527	aspartate kinase activity
LDX55_05835	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LDX55_05850	COG2814	Major facilitator Superfamily
LDX55_05855	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
LDX55_05860	COG0436	Aminotransferase
LDX55_05880	COG2011	ABC-type metal ion transport system permease component
LDX55_05885	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LDX55_05890	COG1464	Belongs to the NlpA lipoprotein family
LDX55_05900	COG1506	peptidase
LDX55_05900	COG4946	Tricorn protease homolog
LDX55_05900	COG0823	Involved in the tonB-independent uptake of proteins
LDX55_05930	COG3590	peptidase
LDX55_05935	COG2814	Major facilitator Superfamily
LDX55_05945	COG0024	Methionine aminopeptidase
LDX55_05950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LDX55_05960	COG0110	maltose O-acetyltransferase activity
LDX55_05970	COG0351	phosphomethylpyrimidine kinase
LDX55_05975	COG2801	Transposase and inactivated derivatives
LDX55_05990	COG2249	NAD(P)H dehydrogenase (quinone) activity
LDX55_06005	COG0601	transmembrane transport
LDX55_06010	COG4608	Belongs to the ABC transporter superfamily
LDX55_06020	COG1278	Cold shock
LDX55_06045	COG2801	Transposase and inactivated derivatives
LDX55_06070	COG0697	spore germination
LDX55_06075	COG0531	amino acid
LDX55_06085	COG2409	Drug exporters of the RND superfamily
LDX55_06085	COG1033	growth of symbiont in host cell
LDX55_06095	COG0697	spore germination
LDX55_06100	COG0656	L-ascorbic acid biosynthetic process
LDX55_06105	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
LDX55_06110	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LDX55_06115	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LDX55_06125	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LDX55_06130	COG0825	malonyl-CoA metabolic process
LDX55_06135	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LDX55_06140	COG0439	Biotin carboxylase
LDX55_06145	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LDX55_06155	COG1028	Short-chain dehydrogenase reductase Sdr
LDX55_06160	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LDX55_06165	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LDX55_06170	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LDX55_06180	COG2801	Transposase and inactivated derivatives
LDX55_06185	COG0778	Nitroreductase
LDX55_06190	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LDX55_06215	COG0488	(ABC) transporter
LDX55_06220	COG0702	epimerase
LDX55_06250	COG2323	membrane
LDX55_06265	COG1272	protein, Hemolysin III
LDX55_06275	COG1131	(ABC) transporter
LDX55_06290	COG1846	Transcriptional regulator
LDX55_06295	COG1113	amino acid transport
LDX55_06300	COG1113	amino acid transport
LDX55_06305	COG0531	amino acid
LDX55_06315	COG0446	pyridine nucleotide-disulphide oxidoreductase
LDX55_06325	COG5263	repeat protein
LDX55_06325	COG0366	Alpha amylase catalytic
LDX55_06330	COG5263	repeat protein
LDX55_06330	COG0366	Alpha amylase catalytic
LDX55_06345	COG4166	transmembrane transport
LDX55_06380	COG1215	transferase activity, transferring glycosyl groups
LDX55_06385	COG0297	glycogen (starch) synthase activity
LDX55_06385	COG0438	transferase activity, transferring glycosyl groups
LDX55_06390	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
LDX55_06395	COG4464	protein tyrosine phosphatase activity
LDX55_06400	COG0489	protein tyrosine kinase activity
LDX55_06410	COG1316	TRANSCRIPTIONal
LDX55_06435	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
LDX55_06445	COG1114	Component of the transport system for branched-chain amino acids
LDX55_06455	COG1114	Component of the transport system for branched-chain amino acids
LDX55_06465	COG1704	LemA family
LDX55_06485	COG0114	fumarate hydratase activity
LDX55_06510	COG3279	Response regulator of the LytR AlgR family
LDX55_06530	COG4166	transmembrane transport
LDX55_06535	COG4166	transmembrane transport
LDX55_06540	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
LDX55_06550	COG2801	Transposase and inactivated derivatives
LDX55_06560	COG1388	LysM domain
LDX55_06570	COG3527	Alpha-acetolactate decarboxylase
LDX55_06575	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
LDX55_06590	COG2801	Transposase and inactivated derivatives
LDX55_06595	COG0693	protein deglycase activity
LDX55_06650	COG0028	Belongs to the TPP enzyme family
LDX55_06655	COG2801	Transposase and inactivated derivatives
LDX55_06680	COG0702	epimerase
LDX55_06685	COG1959	2 iron, 2 sulfur cluster binding
LDX55_06695	COG2814	Major facilitator Superfamily
LDX55_06705	COG0151	Belongs to the GarS family
LDX55_06710	COG0138	bifunctional purine biosynthesis protein purh
LDX55_06715	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LDX55_06720	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LDX55_06730	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LDX55_06735	COG0047	phosphoribosylformylglycinamidine synthase activity
LDX55_06745	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LDX55_06750	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LDX55_06755	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LDX55_06760	COG1686	Belongs to the peptidase S11 family
LDX55_06780	COG0366	Alpha amylase catalytic
LDX55_06780	COG5263	repeat protein
LDX55_06800	COG1476	TRANSCRIPTIONal
LDX55_06805	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LDX55_06825	COG0460	homoserine dehydrogenase
LDX55_06835	COG0083	homoserine kinase activity
LDX55_06865	COG0584	glycerophosphoryl diester phosphodiesterase
LDX55_06890	COG1136	(ABC) transporter
LDX55_06915	COG0446	pyridine nucleotide-disulphide oxidoreductase
LDX55_06945	COG0577	efflux transmembrane transporter activity
LDX55_06945	COG1136	(ABC) transporter
LDX55_06950	COG1309	transcriptional regulator
LDX55_06955	COG0668	transmembrane transport
LDX55_06960	COG0668	transmembrane transport
LDX55_06965	COG0765	amino acid transport
LDX55_06970	COG1126	abc transporter atp-binding protein
LDX55_06975	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LDX55_06990	COG2801	Transposase and inactivated derivatives
LDX55_06995	COG0583	DNA-binding transcription factor activity
LDX55_07030	COG0765	amino acid transport
LDX55_07035	COG1126	abc transporter atp-binding protein
LDX55_07045	COG2814	Major facilitator Superfamily
LDX55_07055	COG2855	membrane
LDX55_07065	COG4152	abc transporter atp-binding protein
LDX55_07075	COG1074	ATP-dependent DNA helicase activity
LDX55_07080	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
LDX55_07110	COG1113	amino acid transport
LDX55_07115	COG1113	amino acid transport
LDX55_07130	COG0667	Aldo Keto reductase
LDX55_07135	COG2252	PERMEase
LDX55_07145	COG0328	RNA-DNA hybrid ribonuclease activity
LDX55_07150	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LDX55_07155	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
LDX55_07160	COG1940	carbohydrate kinase activity
LDX55_07170	COG0346	lactoylglutathione lyase activity
LDX55_07175	COG0481	GTPase activity
LDX55_07180	COG1309	transcriptional regulator
LDX55_07195	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LDX55_07200	COG1121	(ABC) transporter
LDX55_07205	COG0860	N-Acetylmuramoyl-L-alanine amidase
LDX55_07205	COG3103	Sh3 type 3 domain protein
LDX55_07205	COG4991	sh3 domain protein
LDX55_07225	COG2814	Major facilitator Superfamily
LDX55_07230	COG0284	orotidine-5'-phosphate decarboxylase activity
LDX55_07235	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LDX55_07250	COG2801	Transposase and inactivated derivatives
LDX55_07260	COG4166	transmembrane transport
LDX55_07275	COG0460	homoserine dehydrogenase
LDX55_07285	COG2873	o-acetylhomoserine
LDX55_07290	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
LDX55_07295	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
LDX55_07330	COG1126	abc transporter atp-binding protein
LDX55_07335	COG0765	amino acid transport
LDX55_07345	COG0137	argininosuccinate synthase activity
LDX55_07375	COG0681	Belongs to the peptidase S26 family
LDX55_07380	COG0445	tRNA wobble uridine modification
LDX55_07385	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LDX55_07390	COG1847	R3H domain protein
LDX55_07395	COG0706	membrane insertase activity
LDX55_07400	COG0594	ribonuclease P activity
LDX55_07405	COG0230	Belongs to the bacterial ribosomal protein bL34 family