locus-tag	class	description
BXU06_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BXU06_00010	COG0592	DNA-directed DNA polymerase activity
BXU06_00020	COG2337	Toxic component of a toxin-antitoxin (TA) module
BXU06_00035	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
BXU06_00050	COG2959	enzyme of heme biosynthesis
BXU06_00060	COG0181	hydroxymethylbilane synthase activity
BXU06_00065	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BXU06_00075	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BXU06_00080	COG2204	response regulator
BXU06_00085	COG5000	phosphorelay sensor kinase activity
BXU06_00095	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BXU06_00095	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BXU06_00105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BXU06_00110	COG0840	transmembrane signaling receptor activity
BXU06_00115	COG0840	transmembrane signaling receptor activity
BXU06_00120	COG0633	Ferredoxin
BXU06_00120	COG3217	Mosc domain protein beta barrel domain protein
BXU06_00135	COG0840	transmembrane signaling receptor activity
BXU06_00150	COG1131	(ABC) transporter
BXU06_00155	COG0842	Transport permease protein
BXU06_00165	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BXU06_00170	COG2353	YceI-like domain
BXU06_00175	COG2353	YceI-like domain
BXU06_00180	COG3038	cytochrome b561
BXU06_00185	COG3384	dioxygenase
BXU06_00190	COG0583	DNA-binding transcription factor activity
BXU06_00195	COG0625	glutathione transferase activity
BXU06_00210	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BXU06_00215	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BXU06_00225	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BXU06_00230	COG0508	dehydrogenase complex catalyzes the overall conversion of
BXU06_00235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BXU06_00295	COG2815	serine threonine protein kinase
BXU06_00295	COG0515	serine threonine protein kinase
BXU06_00315	COG4659	FMN binding
BXU06_00320	COG4658	electron transport chain
BXU06_00335	COG4657	Part of a membrane complex involved in electron transport
BXU06_00355	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BXU06_00395	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BXU06_00400	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BXU06_00405	COG1127	ABC transporter
BXU06_00440	COG4681	YaeQ
BXU06_00455	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BXU06_00540	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BXU06_00545	COG0583	DNA-binding transcription factor activity
BXU06_00575	COG0675	Transposase, IS605 OrfB family
BXU06_00580	COG4521	taurine ABC transporter
BXU06_00585	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BXU06_00590	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BXU06_00595	COG2175	clavaminate synthase activity
BXU06_00610	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BXU06_00615	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BXU06_00625	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BXU06_00630	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BXU06_00635	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BXU06_00670	COG0405	Gamma-glutamyltransferase
BXU06_00675	COG0640	Transcriptional regulator
BXU06_00680	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BXU06_00685	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BXU06_00690	COG0798	PFAM Bile acid sodium symporter
BXU06_00710	COG0625	glutathione transferase activity
BXU06_00715	COG0583	DNA-binding transcription factor activity
BXU06_00725	COG3039	Transposase
BXU06_00740	COG0632	four-way junction helicase activity
BXU06_00745	COG0671	phosphoesterase, PA-phosphatase related
BXU06_00750	COG2255	four-way junction helicase activity
BXU06_00760	COG0210	DNA helicase
BXU06_00770	COG2841	Protein conserved in bacteria
BXU06_00775	COG1752	Esterase of the alpha-beta hydrolase superfamily
BXU06_00780	COG2226	methyltransferase
BXU06_00785	COG2267	carboxylic ester hydrolase activity
BXU06_00800	COG3039	Transposase
BXU06_00810	COG0583	DNA-binding transcription factor activity
BXU06_00820	COG2171	N-acyltransferase activity
BXU06_00830	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BXU06_00880	COG2884	Cell division ATP-binding protein ftsE
BXU06_00890	COG0612	Peptidase, M16
BXU06_00895	COG0612	Peptidase, M16
BXU06_00900	COG0742	ribosomal rna small subunit methyltransferase
BXU06_00905	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BXU06_00925	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BXU06_00945	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BXU06_00950	COG0081	regulation of translation
BXU06_00955	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BXU06_00960	COG0222	ribosome binding
BXU06_00965	COG0085	RNA polymerase activity
BXU06_00970	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BXU06_00975	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BXU06_00980	COG0049	tRNA binding
BXU06_00985	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BXU06_00990	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BXU06_00995	COG0051	transcription antitermination factor activity, RNA binding
BXU06_01000	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BXU06_01005	COG0088	Forms part of the polypeptide exit tunnel
BXU06_01010	COG0089	rRNA binding
BXU06_01015	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BXU06_01020	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BXU06_01025	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BXU06_01030	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BXU06_01035	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BXU06_01040	COG0255	Belongs to the universal ribosomal protein uL29 family
BXU06_01045	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BXU06_01050	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BXU06_01055	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BXU06_01060	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BXU06_01065	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BXU06_01070	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BXU06_01075	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BXU06_01080	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BXU06_01090	COG1841	ribosomal large subunit assembly
BXU06_01095	COG0200	Binds to the 23S rRNA
BXU06_01100	COG0201	protein transport
BXU06_01105	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BXU06_01110	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BXU06_01115	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BXU06_01120	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BXU06_01125	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BXU06_01130	COG0202	RNA polymerase activity
BXU06_01135	COG0203	ribosomal protein L17
BXU06_01145	COG5001	Diguanylate cyclase
BXU06_01145	COG3300	MHYT domain
BXU06_01155	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BXU06_01160	COG4535	Mg2 and Co2 transporter CorC
BXU06_01165	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BXU06_01170	COG1702	phosphate starvation-inducible protein PhoH
BXU06_01175	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BXU06_01210	COG1012	belongs to the aldehyde dehydrogenase family
BXU06_01225	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BXU06_01230	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BXU06_01240	COG0318	PFAM AMP-dependent synthetase and ligase
BXU06_01245	COG1960	acyl-CoA dehydrogenase activity
BXU06_01255	COG3162	membrane
BXU06_01260	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BXU06_01270	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BXU06_01285	COG2801	Transposase and inactivated derivatives
BXU06_01305	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BXU06_01325	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BXU06_01350	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BXU06_01355	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BXU06_01355	COG2813	Specifically methylates the guanine in position
BXU06_01360	COG2258	MOSC domain
BXU06_01365	COG0505	Belongs to the CarA family
BXU06_01370	COG1396	sequence-specific DNA binding
BXU06_01375	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BXU06_01395	COG4191	Histidine kinase
BXU06_01395	COG0784	Response regulator, receiver
BXU06_01440	COG0583	DNA-binding transcription factor activity
BXU06_01450	COG0546	phosphoglycolate phosphatase activity
BXU06_01455	COG1942	4-Oxalocrotonate Tautomerase
BXU06_01460	COG0584	glycerophosphoryl diester phosphodiesterase
BXU06_01475	COG1012	belongs to the aldehyde dehydrogenase family
BXU06_01480	COG1024	Enoyl-CoA hydratase
BXU06_01485	COG1250	3-hydroxyacyl-CoA dehydrogenase
BXU06_01490	COG2050	protein possibly involved in aromatic compounds catabolism
BXU06_01500	COG0183	Belongs to the thiolase family
BXU06_01510	COG1024	Enoyl-CoA hydratase
BXU06_01525	COG0840	transmembrane signaling receptor activity
BXU06_01530	COG0179	Fumarylacetoacetate (FAA) hydrolase
BXU06_01540	COG1012	belongs to the aldehyde dehydrogenase family
BXU06_01545	COG3384	dioxygenase
BXU06_01550	COG3384	dioxygenase
BXU06_01560	COG3971	2-oxopent-4-enoate hydratase activity
BXU06_01575	COG2814	Major facilitator Superfamily
BXU06_01590	COG0235	Class ii aldolase
BXU06_01600	COG0251	oxidation-reduction process
BXU06_01605	COG3094	Invasion gene expression up-regulator, SirB
BXU06_01620	COG0613	PHP domain protein
BXU06_01625	COG0009	L-threonylcarbamoyladenylate synthase
BXU06_01630	COG1994	Peptidase M50
BXU06_01635	COG0180	Tryptophanyl-tRNA synthetase
BXU06_01650	COG3530	Putative quorum-sensing-regulated virulence factor
BXU06_01655	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
BXU06_01680	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BXU06_01680	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BXU06_01700	COG1660	Displays ATPase and GTPase activities
BXU06_01705	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
BXU06_01715	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BXU06_01720	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BXU06_01725	COG1137	ATPase activity
BXU06_01730	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BXU06_01740	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BXU06_01795	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BXU06_01800	COG1968	undecaprenyl-diphosphatase activity
BXU06_01810	COG0010	Belongs to the arginase family
BXU06_01815	COG0347	Belongs to the P(II) protein family
BXU06_01820	COG0004	ammonium transporteR
BXU06_01825	COG0675	Transposase, IS605 OrfB family
BXU06_01830	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BXU06_01855	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BXU06_01855	COG0446	pyridine nucleotide-disulphide oxidoreductase
BXU06_01865	COG0174	glutamine synthetase
BXU06_01870	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BXU06_01880	COG0069	glutamate synthase activity
BXU06_01885	COG1522	sequence-specific DNA binding
BXU06_01900	COG0693	protein deglycase activity
BXU06_01905	COG0840	transmembrane signaling receptor activity
BXU06_01910	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BXU06_01920	COG1192	Involved in chromosome partitioning
BXU06_01930	COG0514	ATP-dependent DNA helicase (RecQ)
BXU06_01935	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BXU06_01970	COG0560	Phosphoserine phosphatase
BXU06_01980	COG0602	queuosine metabolic process
BXU06_01985	COG0720	synthase
BXU06_01990	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BXU06_02005	COG3220	belongs to the UPF0276 family
BXU06_02015	COG3437	response regulator, receiver
BXU06_02015	COG2770	Histidine kinase
BXU06_02025	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BXU06_02030	COG1758	RNA polymerase activity
BXU06_02035	COG0194	GDP metabolic process
BXU06_02040	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BXU06_02045	COG0424	maF-like protein
BXU06_02050	COG1399	metal-binding, possibly nucleic acid-binding protein
BXU06_02055	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BXU06_02060	COG0416	fatty acid biosynthetic process
BXU06_02065	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BXU06_02075	COG1028	Short-chain dehydrogenase reductase Sdr
BXU06_02080	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BXU06_02085	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BXU06_02090	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BXU06_02105	COG0840	transmembrane signaling receptor activity
BXU06_02115	COG3852	Histidine kinase
BXU06_02135	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BXU06_02140	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BXU06_02145	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BXU06_02155	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BXU06_02155	COG0519	Catalyzes the synthesis of GMP from XMP
BXU06_02160	COG0210	DNA helicase
BXU06_02215	COG2814	Major facilitator Superfamily
BXU06_02220	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
BXU06_02225	COG0179	Fumarylacetoacetate (FAA) hydrolase
BXU06_02245	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BXU06_02250	COG2022	thiamine diphosphate biosynthetic process
BXU06_02275	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BXU06_02285	COG0121	glutamine amidotransferase
BXU06_02295	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BXU06_02310	COG0360	Binds together with S18 to 16S ribosomal RNA
BXU06_02320	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BXU06_02325	COG0359	binds to the 23S rRNA
BXU06_02330	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BXU06_02335	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BXU06_02345	COG0084	hydrolase, TatD family'
BXU06_02350	COG0321	lipoyl(octanoyl) transferase activity
BXU06_02350	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BXU06_02365	COG0494	nUDIX hydrolase
BXU06_02370	COG0187	DNA topoisomerase II activity
BXU06_02375	COG2382	esterase
BXU06_02395	COG4771	TonB-dependent receptor
BXU06_02405	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BXU06_02415	COG5433	transposase activity
BXU06_02425	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BXU06_02430	COG1140	nitrate reductase beta subunit
BXU06_02435	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BXU06_02440	COG2181	nitrate reductase activity
BXU06_02455	COG1196	nuclear chromosome segregation
BXU06_02465	COG2431	L-lysine efflux transmembrane transporter activity
BXU06_02525	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXU06_02530	COG1177	transmembrane transport
BXU06_02535	COG1176	ABC-type spermidine putrescine transport system, permease component I
BXU06_02540	COG3842	ATPase activity
BXU06_02555	COG0174	glutamine synthetase
BXU06_02560	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BXU06_02565	COG1396	sequence-specific DNA binding
BXU06_02565	COG1917	Cupin 2, conserved barrel domain protein
BXU06_02570	COG1012	belongs to the aldehyde dehydrogenase family
BXU06_02580	COG0326	Molecular chaperone. Has ATPase activity
BXU06_02585	COG0697	spore germination
BXU06_02595	COG1414	Transcriptional regulator
BXU06_02620	COG4536	flavin adenine dinucleotide binding
BXU06_02630	COG0237	dephospho-CoA kinase activity
BXU06_02635	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
BXU06_02640	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BXU06_02660	COG1943	Transposase
BXU06_02670	COG0559	Belongs to the binding-protein-dependent transport system permease family
BXU06_02685	COG0410	ABC transporter
BXU06_02690	COG0829	nickel cation binding
BXU06_02695	COG0831	urea catabolic process
BXU06_02700	COG0832	Belongs to the urease beta subunit family
BXU06_02705	COG0804	urea catabolic process
BXU06_02710	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BXU06_02715	COG0830	nickel cation binding
BXU06_02720	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BXU06_02730	COG2719	SpoVR family
BXU06_02735	COG2718	Belongs to the UPF0229 family
BXU06_02740	COG2766	serine protein kinase
BXU06_02745	COG1115	amino acid carrier protein
BXU06_02750	COG2205	protein histidine kinase activity
BXU06_02755	COG0745	RESPONSE REGULATOR receiver
BXU06_02760	COG0527	aspartate kinase activity
BXU06_02800	COG0840	transmembrane signaling receptor activity
BXU06_02805	COG0840	transmembrane signaling receptor activity
BXU06_02825	COG4771	TonB-dependent receptor
BXU06_02835	COG0348	domain, Protein
BXU06_02870	COG0675	Transposase, IS605 OrfB family
BXU06_02885	COG4774	siderophore transport
BXU06_02930	COG0577	efflux transmembrane transporter activity
BXU06_02930	COG1136	(ABC) transporter
BXU06_02935	COG0577	efflux transmembrane transporter activity
BXU06_02935	COG1136	(ABC) transporter
BXU06_02960	COG0583	DNA-binding transcription factor activity
BXU06_02970	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BXU06_02975	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BXU06_02980	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BXU06_02985	COG0316	Belongs to the HesB IscA family
BXU06_02990	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BXU06_02995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXU06_03000	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BXU06_03010	COG1280	lysine exporter protein (LysE YggA)
BXU06_03025	COG3038	cytochrome b561
BXU06_03030	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BXU06_03035	COG2223	nitrite transmembrane transporter activity
BXU06_03045	COG1538	Outer membrane efflux protein
BXU06_03050	COG1136	(ABC) transporter
BXU06_03050	COG0577	efflux transmembrane transporter activity
BXU06_03055	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BXU06_03080	COG1960	acyl-CoA dehydrogenase activity
BXU06_03085	COG0183	Belongs to the thiolase family
BXU06_03090	COG0789	Transcriptional regulator
BXU06_03095	COG1250	3-hydroxyacyl-CoA dehydrogenase
BXU06_03100	COG1022	Amp-dependent synthetase and ligase
BXU06_03110	COG0559	Belongs to the binding-protein-dependent transport system permease family
BXU06_03150	COG1024	Enoyl-CoA hydratase
BXU06_03155	COG1024	Enoyl-CoA hydratase
BXU06_03165	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BXU06_03175	COG3706	GGDEF domain
BXU06_03185	COG0840	transmembrane signaling receptor activity
BXU06_03205	COG4657	Part of a membrane complex involved in electron transport
BXU06_03210	COG2878	Part of a membrane complex involved in electron transport
BXU06_03215	COG4656	Part of a membrane complex involved in electron transport
BXU06_03220	COG4658	electron transport chain
BXU06_03225	COG4659	FMN binding
BXU06_03235	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BXU06_03240	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BXU06_03245	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BXU06_03250	COG0497	DNA recombination
BXU06_03255	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BXU06_03260	COG2198	Histidine kinase
BXU06_03260	COG0643	Histidine kinase
BXU06_03265	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
BXU06_03270	COG0745	RESPONSE REGULATOR receiver
BXU06_03275	COG0835	chemotaxis
BXU06_03275	COG0784	Response regulator, receiver
BXU06_03280	COG0784	Response regulator, receiver
BXU06_03280	COG0835	chemotaxis
BXU06_03285	COG3852	Histidine kinase
BXU06_03295	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BXU06_03305	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BXU06_03315	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BXU06_03320	COG0277	FAD linked oxidase domain protein
BXU06_03325	COG0528	UMP kinase activity
BXU06_03330	COG0528	UMP kinase activity
BXU06_03340	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BXU06_03345	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BXU06_03355	COG2197	response regulator
BXU06_03360	COG3850	Histidine kinase
BXU06_03365	COG0288	reversible hydration of carbon dioxide
BXU06_03370	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BXU06_03385	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BXU06_03400	COG1393	Belongs to the ArsC family
BXU06_03405	COG2223	nitrite transmembrane transporter activity
BXU06_03440	COG2974	May be involved in recombination
BXU06_03445	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BXU06_03455	COG0039	L-malate dehydrogenase activity
BXU06_03460	COG2188	Transcriptional regulator
BXU06_03465	COG2009	succinate dehydrogenase
BXU06_03475	COG1053	succinate dehydrogenase
BXU06_03480	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BXU06_03485	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BXU06_03495	COG0567	Dehydrogenase, E1 component
BXU06_03500	COG0508	dehydrogenase complex catalyzes the overall conversion of
BXU06_03505	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BXU06_03510	COG0045	succinate-CoA ligase (ADP-forming) activity
BXU06_03515	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BXU06_03520	COG0675	Transposase, IS605 OrfB family
BXU06_03525	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BXU06_03540	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BXU06_03555	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BXU06_03575	COG0105	UTP biosynthetic process
BXU06_03580	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BXU06_03585	COG1426	Protein conserved in bacteria
BXU06_03590	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BXU06_03595	COG0124	histidyl-tRNA synthetase
BXU06_03600	COG2976	Protein conserved in bacteria
BXU06_03605	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXU06_03610	COG1160	GTP binding
BXU06_03615	COG1923	regulation of RNA biosynthetic process
BXU06_03620	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BXU06_03625	COG0330	HflC and HflK could
BXU06_03630	COG0330	HflC and HflK could
BXU06_03635	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BXU06_03640	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BXU06_03660	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BXU06_03665	COG0675	Transposase, IS605 OrfB family
BXU06_03675	COG3459	Glycosyltransferase 36 associated
BXU06_03680	COG0166	Belongs to the GPI family
BXU06_03685	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
BXU06_03695	COG3237	CsbD-like
BXU06_03700	COG2823	Periplasmic or secreted lipoprotein
BXU06_03740	COG2308	Evidence 4 Homologs of previously reported genes of
BXU06_03755	COG2308	Evidence 4 Homologs of previously reported genes of
BXU06_03755	COG2307	Protein conserved in bacteria
BXU06_03760	COG1305	Transglutaminase-like
BXU06_03785	COG2217	Heavy metal translocating P-type atpase
BXU06_03795	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BXU06_03820	COG0675	Transposase, IS605 OrfB family
BXU06_03830	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BXU06_03860	COG1678	Uncharacterized ACR, COG1678
BXU06_03870	COG0675	Transposase, IS605 OrfB family
BXU06_03885	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BXU06_03890	COG2814	Major facilitator Superfamily
BXU06_03900	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BXU06_03925	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BXU06_03935	COG3039	Transposase
BXU06_03945	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BXU06_03945	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BXU06_03955	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BXU06_03975	COG1846	Transcriptional regulator
BXU06_03980	COG0697	spore germination
BXU06_03985	COG2962	Rard protein
BXU06_03995	COG0166	Belongs to the GPI family
BXU06_04000	COG2267	carboxylic ester hydrolase activity
BXU06_04030	COG1944	ATP diphosphatase activity
BXU06_04035	COG0312	modulator of DNA gyrase
BXU06_04040	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BXU06_04050	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BXU06_04060	COG0307	riboflavin synthase, alpha
BXU06_04065	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BXU06_04095	COG1733	regulation of RNA biosynthetic process
BXU06_04105	COG2169	Transcriptional regulator
BXU06_04105	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BXU06_04110	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BXU06_04120	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXU06_04125	COG2188	Transcriptional regulator
BXU06_04130	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BXU06_04135	COG5002	protein histidine kinase activity
BXU06_04135	COG5001	Diguanylate cyclase
BXU06_04135	COG3447	MASE1 domain protein
BXU06_04140	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BXU06_04140	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BXU06_04165	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BXU06_04170	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BXU06_04185	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BXU06_04200	COG2866	Carboxypeptidase
BXU06_04250	COG2205	protein histidine kinase activity
BXU06_04250	COG0784	Response regulator, receiver
BXU06_04270	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BXU06_04275	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BXU06_04280	COG0586	Pfam SNARE associated Golgi protein
BXU06_04285	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BXU06_04290	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BXU06_04295	COG1862	Preprotein translocase
BXU06_04300	COG0343	queuine tRNA-ribosyltransferase activity
BXU06_04310	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BXU06_04315	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BXU06_04320	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BXU06_04325	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BXU06_04330	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BXU06_04335	COG0072	phenylalanine-tRNA ligase activity
BXU06_04335	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BXU06_04340	COG0776	regulation of translation
BXU06_04385	COG4191	Histidine kinase
BXU06_04410	COG1857	crispr-associated protein
BXU06_04425	COG1518	maintenance of DNA repeat elements
BXU06_04430	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BXU06_04445	COG0736	holo-[acyl-carrier-protein] synthase activity
BXU06_04450	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BXU06_04455	COG1381	Involved in DNA repair and RecF pathway recombination
BXU06_04460	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BXU06_04465	COG0571	ribonuclease III activity
BXU06_04475	COG0481	GTPase activity
BXU06_04485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BXU06_04510	COG3781	membrane
BXU06_04525	COG0544	peptidyl-prolyl cis-trans isomerase activity
BXU06_04530	COG0740	serine-type endopeptidase activity
BXU06_04535	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BXU06_04540	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BXU06_04560	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BXU06_04590	COG0583	DNA-binding transcription factor activity
BXU06_04600	COG0667	Aldo Keto reductase
BXU06_04620	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BXU06_04620	COG4651	solute:proton antiporter activity
BXU06_04625	COG0018	arginyl-trna synthetase
BXU06_04645	COG1028	Short-chain dehydrogenase reductase Sdr
BXU06_04650	COG0583	DNA-binding transcription factor activity
BXU06_04660	COG0047	phosphoribosylformylglycinamidine synthase activity
BXU06_04660	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BXU06_04675	COG0154	amidase activity
BXU06_04690	COG0525	valine-tRNA ligase activity
BXU06_04695	COG3706	GGDEF domain
BXU06_04695	COG0745	RESPONSE REGULATOR receiver
BXU06_04710	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BXU06_04715	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BXU06_04720	COG1752	Esterase of the alpha-beta hydrolase superfamily
BXU06_04725	COG0765	amino acid transport
BXU06_04740	COG0513	Belongs to the DEAD box helicase family
BXU06_04745	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BXU06_04765	COG3706	GGDEF domain
BXU06_04785	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BXU06_04795	COG2095	MarC family integral membrane protein
BXU06_04815	COG0598	Magnesium transport protein CorA
BXU06_04820	COG0248	Ppx GppA phosphatase
BXU06_04825	COG0704	Plays a role in the regulation of phosphate uptake
BXU06_04830	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BXU06_04835	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BXU06_04840	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BXU06_04850	COG0328	RNA-DNA hybrid ribonuclease activity
BXU06_04855	COG2226	methyltransferase
BXU06_04860	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BXU06_04865	COG0741	lytic transglycosylase activity
BXU06_04865	COG1388	LysM domain
BXU06_04875	COG0546	phosphoglycolate phosphatase activity
BXU06_04905	COG0542	response to heat
BXU06_04910	COG0840	transmembrane signaling receptor activity
BXU06_04930	COG2204	response regulator
BXU06_04940	COG1396	sequence-specific DNA binding
BXU06_04945	COG3135	benzoate transporter
BXU06_04950	COG0513	Belongs to the DEAD box helicase family
BXU06_04955	COG0745	RESPONSE REGULATOR receiver
BXU06_04960	COG2084	Dehydrogenase
BXU06_04965	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BXU06_04975	COG1024	Enoyl-CoA hydratase
BXU06_04980	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
BXU06_04980	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXU06_04990	COG0564	pseudouridine synthase activity
BXU06_05005	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BXU06_05010	COG1674	ftsk spoiiie
BXU06_05040	COG1136	(ABC) transporter
BXU06_05070	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BXU06_05085	COG0254	rRNA binding
BXU06_05105	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BXU06_05165	COG1136	(ABC) transporter
BXU06_05185	COG1129	ABC transporter
BXU06_05200	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BXU06_05210	COG0583	DNA-binding transcription factor activity
BXU06_05215	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BXU06_05220	COG0066	3-isopropylmalate dehydratase activity
BXU06_05225	COG0473	3-isopropylmalate dehydrogenase activity
BXU06_05255	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BXU06_05260	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BXU06_05275	COG3220	belongs to the UPF0276 family
BXU06_05295	COG1279	arginine transmembrane transporter activity
BXU06_05300	COG1666	GTP binding
BXU06_05315	COG0137	argininosuccinate synthase activity
BXU06_05320	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BXU06_05325	COG1982	Orn Lys Arg decarboxylase major
BXU06_05335	COG2823	Periplasmic or secreted lipoprotein
BXU06_05340	COG0488	(ABC) transporter
BXU06_05345	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BXU06_05350	COG1765	OsmC-like protein
BXU06_05360	COG2824	Alkylphosphonate utilization operon protein PhnA
BXU06_05370	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BXU06_05380	COG3012	SEC-C Motif Domain Protein
BXU06_05405	COG0028	Belongs to the TPP enzyme family
BXU06_05410	COG0440	acetolactate synthase activity
BXU06_05425	COG5433	transposase activity
BXU06_05435	COG3123	guanosine phosphorylase activity
BXU06_05440	COG1393	Belongs to the ArsC family
BXU06_05445	COG0318	PFAM AMP-dependent synthetase and ligase
BXU06_05450	COG0779	Required for maturation of 30S ribosomal subunits
BXU06_05455	COG2251	uridine kinase activity
BXU06_05455	COG0195	Participates in both transcription termination and antitermination
BXU06_05460	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BXU06_05465	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BXU06_05470	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BXU06_05475	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BXU06_05480	COG1185	polyribonucleotide nucleotidyltransferase activity
BXU06_05485	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BXU06_05515	COG0174	glutamine synthetase
BXU06_05525	COG1396	sequence-specific DNA binding
BXU06_05525	COG1917	Cupin 2, conserved barrel domain protein
BXU06_05530	COG1309	transcriptional regulator
BXU06_05535	COG0859	PFAM glycosyl transferase family 9
BXU06_05555	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BXU06_05560	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BXU06_05565	COG0159	tryptophan synthase activity
BXU06_05570	COG0133	tryptophan synthase activity
BXU06_05575	COG0135	phosphoribosylanthranilate isomerase activity
BXU06_05580	COG0101	tRNA pseudouridine synthase activity
BXU06_05610	COG1607	acyl-coa hydrolase
BXU06_05615	COG0697	spore germination
BXU06_05620	COG0659	secondary active sulfate transmembrane transporter activity
BXU06_05635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BXU06_05645	COG1116	anion transmembrane transporter activity
BXU06_05650	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BXU06_05660	COG0243	molybdopterin cofactor binding
BXU06_05680	COG1024	Enoyl-CoA hydratase
BXU06_05685	COG0596	Alpha beta hydrolase
BXU06_05690	COG1472	Belongs to the glycosyl hydrolase 3 family
BXU06_05695	COG0494	nUDIX hydrolase
BXU06_05710	COG0840	transmembrane signaling receptor activity
BXU06_05730	COG3039	Transposase
BXU06_05740	COG0330	HflC and HflK could
BXU06_05745	COG0840	transmembrane signaling receptor activity
BXU06_05760	COG0778	Nitroreductase
BXU06_05785	COG3311	Transcriptional regulator
BXU06_05820	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BXU06_05830	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BXU06_05855	COG0300	oxidoreductase activity
BXU06_05860	COG0861	Integral membrane protein TerC family
BXU06_05870	COG2003	Belongs to the UPF0758 family
BXU06_05875	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BXU06_05885	COG2096	Adenosyltransferase
BXU06_05895	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BXU06_05900	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BXU06_05925	COG2832	Protein of unknown function (DUF454)
BXU06_05930	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BXU06_05945	COG0494	nUDIX hydrolase
BXU06_05960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXU06_05990	COG2902	Dehydrogenase
BXU06_06000	COG5433	transposase activity
BXU06_06005	COG0583	DNA-binding transcription factor activity
BXU06_06015	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BXU06_06025	COG3093	addiction module antidote protein HigA
BXU06_06030	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
BXU06_06035	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BXU06_06040	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BXU06_06050	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BXU06_06060	COG0420	3'-5' exonuclease activity
BXU06_06065	COG0419	ATPase involved in DNA repair
BXU06_06085	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BXU06_06090	COG0857	belongs to the CobB CobQ family
BXU06_06090	COG0280	phosphate acetyltransferase
BXU06_06100	COG2733	membrane
BXU06_06110	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BXU06_06120	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BXU06_06125	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BXU06_06130	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BXU06_06135	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BXU06_06155	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BXU06_06165	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BXU06_06170	COG0233	cytoplasmic translational termination
BXU06_06175	COG0528	UMP kinase activity
BXU06_06180	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BXU06_06185	COG0052	Belongs to the universal ribosomal protein uS2 family
BXU06_06205	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BXU06_06210	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BXU06_06220	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXU06_06230	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BXU06_06245	COG3162	membrane
BXU06_06250	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BXU06_06255	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BXU06_06300	COG3039	Transposase
BXU06_06310	COG0700	Nucleoside recognition
BXU06_06315	COG0840	transmembrane signaling receptor activity
BXU06_06330	COG0675	Transposase, IS605 OrfB family
BXU06_06350	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BXU06_06360	COG0406	alpha-ribazole phosphatase activity
BXU06_06365	COG2944	sequence-specific DNA binding
BXU06_06380	COG5433	transposase activity
BXU06_06395	COG3275	phosphorelay sensor kinase activity
BXU06_06415	COG0756	dUTP diphosphatase activity
BXU06_06420	COG5433	transposase activity
BXU06_06425	COG3622	Belongs to the hyi family
BXU06_06445	COG3622	Belongs to the hyi family
BXU06_06450	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BXU06_06455	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BXU06_06465	COG2350	Protein conserved in bacteria
BXU06_06470	COG2917	probably involved in intracellular septation
BXU06_06475	COG1643	Atp-dependent helicase
BXU06_06495	COG1763	Mo-molybdopterin cofactor biosynthetic process
BXU06_06505	COG0735	belongs to the Fur family
BXU06_06510	COG0523	cobalamin synthesis protein
BXU06_06515	COG1121	(ABC) transporter
BXU06_06535	COG0251	oxidation-reduction process
BXU06_06570	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BXU06_06595	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BXU06_06600	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BXU06_06640	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXU06_06645	COG1846	Transcriptional regulator
BXU06_06650	COG0386	Belongs to the glutathione peroxidase family
BXU06_06660	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BXU06_06670	COG0840	transmembrane signaling receptor activity
BXU06_06680	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BXU06_06710	COG0038	chloride channel
BXU06_06720	COG4206	TonB-dependent receptor
BXU06_06730	COG3022	response to hydroperoxide
BXU06_06735	COG0628	permease
BXU06_06740	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BXU06_06745	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BXU06_06755	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BXU06_06755	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BXU06_06795	COG0793	Belongs to the peptidase S41A family
BXU06_06800	COG4942	peptidase
BXU06_06810	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BXU06_06825	COG2814	Major facilitator Superfamily
BXU06_06830	COG0629	single-stranded DNA binding
BXU06_06835	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BXU06_06845	COG3128	pkhd-type hydroxylase
BXU06_06850	COG4774	siderophore transport
BXU06_06855	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
BXU06_06920	COG0305	Participates in initiation and elongation during chromosome replication
BXU06_06925	COG2173	Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide
BXU06_06940	COG2081	HI0933 family
BXU06_06945	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BXU06_06950	COG0024	Methionine aminopeptidase
BXU06_06965	COG3411	Ferredoxin
BXU06_06975	COG1420	regulation of RNA biosynthetic process
BXU06_06990	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BXU06_06995	COG2137	regulation of response to DNA damage stimulus
BXU06_07000	COG0840	transmembrane signaling receptor activity
BXU06_07015	COG0840	transmembrane signaling receptor activity
BXU06_07025	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BXU06_07035	COG0129	dihydroxy-acid dehydratase activity
BXU06_07045	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BXU06_07050	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BXU06_07060	COG2951	lytic endotransglycosylase activity
BXU06_07080	COG0556	nucleotide-excision repair
BXU06_07090	COG0556	nucleotide-excision repair
BXU06_07105	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BXU06_07110	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BXU06_07115	COG0443	Heat shock 70 kDa protein
BXU06_07130	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BXU06_07160	COG1028	Short-chain dehydrogenase reductase Sdr
BXU06_07165	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BXU06_07170	COG0321	lipoyl(octanoyl) transferase activity
BXU06_07175	COG2921	Belongs to the UPF0250 family
BXU06_07180	COG1686	Belongs to the peptidase S11 family
BXU06_07210	COG4628	conserved protein (DUF2132)
BXU06_07220	COG3039	Transposase
BXU06_07240	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BXU06_07250	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BXU06_07260	COG0482	sulfurtransferase activity
BXU06_07300	COG1196	nuclear chromosome segregation
BXU06_07325	COG0488	(ABC) transporter
BXU06_07330	COG3706	GGDEF domain
BXU06_07335	COG0492	ferredoxin-NADP+ reductase activity
BXU06_07345	COG4191	Histidine kinase
BXU06_07360	COG1518	maintenance of DNA repeat elements
BXU06_07365	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BXU06_07385	COG1337	RAMP superfamily
BXU06_07415	COG0564	pseudouridine synthase activity
BXU06_07420	COG0259	pyridoxamine-phosphate oxidase activity
BXU06_07430	COG1136	(ABC) transporter
BXU06_07435	COG3264	Mechanosensitive ion channel
BXU06_07435	COG1511	domain protein
BXU06_07450	COG3568	Endonuclease Exonuclease Phosphatase
BXU06_07465	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BXU06_07470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BXU06_07470	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BXU06_07480	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BXU06_07485	COG0402	S-adenosylhomocysteine deaminase activity
BXU06_07490	COG3842	ATPase activity
BXU06_07500	COG1176	ABC-type spermidine putrescine transport system, permease component I
BXU06_07505	COG1177	transmembrane transport
BXU06_07535	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BXU06_07545	COG1960	acyl-CoA dehydrogenase activity
BXU06_07555	COG4172	Belongs to the ABC transporter superfamily
BXU06_07560	COG0791	NLP P60 protein
BXU06_07580	COG0285	dihydrofolate synthase activity
BXU06_07605	COG0675	Transposase, IS605 OrfB family
BXU06_07610	COG0678	peroxiredoxin activity
BXU06_07610	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BXU06_07615	COG0739	heme binding
BXU06_07615	COG1196	nuclear chromosome segregation
BXU06_07615	COG0741	lytic transglycosylase activity
BXU06_07620	COG0702	epimerase
BXU06_07625	COG0617	tRNA 3'-terminal CCA addition
BXU06_07635	COG2258	MOSC domain
BXU06_07640	COG1607	acyl-coa hydrolase
BXU06_07650	COG1250	3-hydroxyacyl-CoA dehydrogenase
BXU06_07650	COG1024	Enoyl-CoA hydratase
BXU06_07655	COG0183	Belongs to the thiolase family
BXU06_07660	COG0675	Transposase, IS605 OrfB family
BXU06_07675	COG0506	proline dehydrogenase activity
BXU06_07675	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BXU06_07675	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BXU06_07690	COG0287	Prephenate dehydrogenase
BXU06_07700	COG0494	nUDIX hydrolase
BXU06_07715	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BXU06_07725	COG0842	Transport permease protein
BXU06_07730	COG0842	Transport permease protein
BXU06_07730	COG1129	ABC transporter
BXU06_07735	COG2010	Cytochrome c
BXU06_07740	COG1131	(ABC) transporter
BXU06_07745	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BXU06_07760	COG5433	transposase activity
BXU06_07765	COG4206	TonB-dependent receptor
BXU06_07770	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BXU06_07775	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BXU06_07785	COG1797	cobyrinic acid a,c-diamide synthase activity
BXU06_07800	COG1937	Protein conserved in bacteria
BXU06_07810	COG2217	Heavy metal translocating P-type atpase
BXU06_07835	COG4239	(ABC) transporter, permease
BXU06_07840	COG0745	RESPONSE REGULATOR receiver
BXU06_07840	COG3706	GGDEF domain
BXU06_07845	COG4174	ABC transporter (Permease)
BXU06_07850	COG4166	transmembrane transport
BXU06_07860	COG1722	exodeoxyribonuclease VII activity
BXU06_07865	COG0142	geranyltranstransferase activity
BXU06_07870	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BXU06_07875	COG3174	membrane
BXU06_07895	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BXU06_07900	COG0534	Mate efflux family protein
BXU06_07925	COG0675	Transposase, IS605 OrfB family
BXU06_07940	COG1199	ATP-dependent helicase activity
BXU06_07950	COG0675	Transposase, IS605 OrfB family
BXU06_07960	COG0675	Transposase, IS605 OrfB family
BXU06_08005	COG1469	GTP cyclohydrolase I activity
BXU06_08020	COG0675	Transposase, IS605 OrfB family
BXU06_08035	COG0501	Belongs to the peptidase M48B family
BXU06_08050	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BXU06_08080	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BXU06_08085	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BXU06_08090	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BXU06_08110	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BXU06_08120	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BXU06_08130	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BXU06_08155	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BXU06_08165	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BXU06_08170	COG0795	lipopolysaccharide-transporting ATPase activity
BXU06_08180	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BXU06_08205	COG1028	Short-chain dehydrogenase reductase Sdr
BXU06_08210	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BXU06_08215	COG1562	ergosterol biosynthetic process
BXU06_08245	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BXU06_08250	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BXU06_08250	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BXU06_08280	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BXU06_08285	COG0751	glycine-tRNA ligase activity
BXU06_08295	COG0752	glycyl-tRNA synthetase alpha subunit
BXU06_08305	COG0436	Aminotransferase
BXU06_08355	COG0675	Transposase, IS605 OrfB family
BXU06_08360	COG1492	cobalamin metabolic process
BXU06_08375	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BXU06_08380	COG1595	DNA-templated transcription, initiation
BXU06_08395	COG0791	NLP P60 protein
BXU06_08405	COG0745	RESPONSE REGULATOR receiver
BXU06_08410	COG2205	protein histidine kinase activity
BXU06_08415	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BXU06_08420	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BXU06_08425	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BXU06_08435	COG5001	Diguanylate cyclase
BXU06_08435	COG3300	MHYT domain
BXU06_08440	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BXU06_08470	COG0175	sulfate reduction
BXU06_08475	COG2895	sulfate adenylyltransferase (ATP) activity
BXU06_08485	COG0309	Hydrogenase expression formation protein (HypE)
BXU06_08500	COG2827	Endonuclease containing a URI domain
BXU06_08520	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BXU06_08525	COG1773	rubredoxin
BXU06_08590	COG0322	excinuclease ABC activity
BXU06_08595	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BXU06_08635	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BXU06_08640	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BXU06_08645	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BXU06_08650	COG1428	Deoxynucleoside kinase
BXU06_08660	COG0617	tRNA 3'-terminal CCA addition
BXU06_08670	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BXU06_08695	COG0183	Belongs to the thiolase family
BXU06_08700	COG0840	transmembrane signaling receptor activity
BXU06_08710	COG0675	Transposase, IS605 OrfB family
BXU06_08715	COG0625	glutathione transferase activity
BXU06_08745	COG0730	response to heat
BXU06_08760	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BXU06_08765	COG3284	Transcriptional regulator
BXU06_08805	COG1881	PFAM PEBP family protein
BXU06_08830	COG0281	malic enzyme
BXU06_08830	COG0280	phosphate acetyltransferase
BXU06_08850	COG2226	methyltransferase
BXU06_08855	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BXU06_08855	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BXU06_08860	COG0489	protein tyrosine kinase activity
BXU06_08865	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BXU06_08935	COG0583	DNA-binding transcription factor activity
BXU06_08975	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BXU06_08985	COG0312	modulator of DNA gyrase
BXU06_08990	COG3028	Belongs to the UPF0307 family
BXU06_08995	COG0521	Mo-molybdopterin cofactor biosynthetic process
BXU06_09000	COG0429	hydrolase of the alpha beta-hydrolase fold
BXU06_09005	COG0134	indole-3-glycerol-phosphate synthase activity
BXU06_09015	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BXU06_09030	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BXU06_09035	COG3842	ATPase activity
BXU06_09065	COG0022	dehydrogenase e1 component
BXU06_09075	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXU06_09090	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BXU06_09095	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BXU06_09115	COG2062	phosphohistidine phosphatase, SixA
BXU06_09120	COG1346	cytolysis
BXU06_09135	COG3161	chorismate lyase activity
BXU06_09140	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BXU06_09150	COG2816	NAD+ diphosphatase activity
BXU06_09160	COG0037	tRNA processing
BXU06_09165	COG0825	malonyl-CoA metabolic process
BXU06_09195	COG2195	Cleaves the N-terminal amino acid of tripeptides
BXU06_09200	COG5265	(ABC) transporter
BXU06_09205	COG2967	ApaG domain
BXU06_09220	COG0410	ABC transporter
BXU06_09240	COG3138	arginine N-succinyltransferase
BXU06_09280	COG1960	acyl-CoA dehydrogenase activity
BXU06_09285	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BXU06_09290	COG1024	Enoyl-CoA hydratase
BXU06_09310	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BXU06_09320	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXU06_09325	COG0348	domain, Protein
BXU06_09330	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BXU06_09335	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BXU06_09340	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BXU06_09355	COG2188	Transcriptional regulator
BXU06_09360	COG1840	ABC-type Fe3 transport system, periplasmic component
BXU06_09370	COG3842	ATPase activity
BXU06_09390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXU06_09395	COG0840	transmembrane signaling receptor activity
BXU06_09410	COG0717	Belongs to the dCTP deaminase family
BXU06_09450	COG0840	transmembrane signaling receptor activity
BXU06_09460	COG1028	Short-chain dehydrogenase reductase Sdr
BXU06_09465	COG3237	CsbD-like
BXU06_09480	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BXU06_09535	COG3829	transcription factor binding
BXU06_09550	COG1335	isochorismatase
BXU06_09555	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BXU06_09560	COG1561	YicC-like family, N-terminal region
BXU06_09575	COG4181	ATPase activity
BXU06_09580	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BXU06_09595	COG0557	exoribonuclease II activity
BXU06_09600	COG0753	catalase activity
BXU06_09625	COG4774	siderophore transport
BXU06_09630	COG3128	pkhd-type hydroxylase
BXU06_09635	COG5433	transposase activity
BXU06_09665	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BXU06_09675	COG5002	protein histidine kinase activity
BXU06_09675	COG2198	Histidine kinase
BXU06_09675	COG0784	Response regulator, receiver
BXU06_09680	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BXU06_09690	COG0215	cysteine-tRNA ligase activity
BXU06_09705	COG1256	bacterial-type flagellum assembly
BXU06_09715	COG1706	bacterial-type flagellum-dependent cell motility
BXU06_09720	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BXU06_09725	COG4786	Flagellar basal body rod
BXU06_09730	COG4787	bacterial-type flagellum-dependent cell motility
BXU06_09735	COG1749	Flagellar hook protein flgE
BXU06_09740	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BXU06_09745	COG1558	bacterial-type flagellum-dependent cell motility
BXU06_09750	COG1815	bacterial-type flagellum-dependent cell motility
BXU06_09760	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BXU06_09770	COG0730	response to heat
BXU06_09795	COG2171	N-acyltransferase activity
BXU06_09815	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BXU06_09875	COG2084	Dehydrogenase
BXU06_09895	COG0675	Transposase, IS605 OrfB family
BXU06_09900	COG2239	Acts as a magnesium transporter
BXU06_09905	COG2890	protein-(glutamine-N5) methyltransferase activity
BXU06_09910	COG2252	PERMEase
BXU06_09915	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BXU06_09925	COG0583	DNA-binding transcription factor activity
BXU06_09930	COG0840	transmembrane signaling receptor activity
BXU06_09950	COG0840	transmembrane signaling receptor activity
BXU06_09955	COG0242	peptide deformylase activity
BXU06_09975	COG1573	uracil-dna glycosylase
BXU06_09995	COG1570	exodeoxyribonuclease VII activity
BXU06_10000	COG0811	peptide transport
BXU06_10005	COG0848	biopolymer transport protein
BXU06_10010	COG1663	tetraacyldisaccharide 4'-kinase activity
BXU06_10015	COG2835	tetraacyldisaccharide 4'-kinase activity
BXU06_10020	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BXU06_10025	COG0563	adenylate kinase activity
BXU06_10030	COG0205	6-phosphofructokinase activity
BXU06_10045	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BXU06_10050	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BXU06_10080	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BXU06_10085	COG0123	including yeast histone deacetylase and acetoin utilization protein
BXU06_10090	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BXU06_10095	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BXU06_10105	COG2201	protein-glutamate methylesterase activity
BXU06_10110	COG2204	response regulator
BXU06_10115	COG1677	Flagellar hook-basal body complex protein FliE
BXU06_10125	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BXU06_10135	COG1157	protein secretion by the type III secretion system
BXU06_10160	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BXU06_10175	COG1987	bacterial-type flagellum assembly
BXU06_10185	COG0217	transcriptional regulatory protein
BXU06_10190	COG0006	proline dipeptidase activity
BXU06_10195	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BXU06_10200	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BXU06_10220	COG2801	Transposase and inactivated derivatives
BXU06_10240	COG0484	heat shock protein binding
BXU06_10245	COG0443	Heat shock 70 kDa protein
BXU06_10250	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BXU06_10260	COG3706	GGDEF domain
BXU06_10285	COG0004	ammonium transporteR
BXU06_10310	COG0348	domain, Protein
BXU06_10330	COG3278	Belongs to the heme-copper respiratory oxidase family
BXU06_10340	COG0308	aminopeptidase N
BXU06_10345	COG0477	Major facilitator Superfamily
BXU06_10375	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BXU06_10380	COG2864	formate dehydrogenase
BXU06_10385	COG0437	4 iron, 4 sulfur cluster binding
BXU06_10390	COG0243	molybdopterin cofactor binding
BXU06_10390	COG3383	formate dehydrogenase (NAD+) activity
BXU06_10400	COG0788	formyltetrahydrofolate deformylase activity
BXU06_10405	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BXU06_10435	COG1530	ribonuclease E activity
BXU06_10455	COG0616	signal peptide processing
BXU06_10455	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BXU06_10465	COG2308	Evidence 4 Homologs of previously reported genes of
BXU06_10485	COG0167	dihydroorotate dehydrogenase activity
BXU06_10490	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BXU06_10495	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BXU06_10505	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BXU06_10510	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BXU06_10515	COG0495	leucyl-tRNA aminoacylation
BXU06_10525	COG1466	dna polymerase III delta subunit
BXU06_10530	COG1028	Short-chain dehydrogenase reductase Sdr
BXU06_10535	COG0488	(ABC) transporter
BXU06_10540	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BXU06_10545	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
BXU06_10555	COG2850	peptidyl-arginine hydroxylation
BXU06_10570	COG0183	Belongs to the thiolase family
BXU06_10575	COG3243	poly(R)-hydroxyalkanoic acid synthase
BXU06_10580	COG0679	Auxin Efflux Carrier
BXU06_10590	COG4191	Histidine kinase
BXU06_10595	COG2204	response regulator
BXU06_10600	COG1943	Transposase
BXU06_10605	COG5001	Diguanylate cyclase
BXU06_10605	COG3300	MHYT domain
BXU06_10610	COG1970	mechanosensitive ion channel activity
BXU06_10620	COG0590	tRNA wobble adenosine to inosine editing
BXU06_10625	COG1376	ErfK ybiS ycfS ynhG family protein
BXU06_10635	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BXU06_10645	COG0840	transmembrane signaling receptor activity
BXU06_10690	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BXU06_10700	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BXU06_10710	COG0802	atpase or kinase
BXU06_10715	COG0860	N-Acetylmuramoyl-L-alanine amidase
BXU06_10725	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BXU06_10730	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BXU06_10740	COG0084	hydrolase, TatD family'
BXU06_10750	COG0268	Binds directly to 16S ribosomal RNA
BXU06_10785	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
BXU06_10800	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BXU06_10805	COG0583	DNA-binding transcription factor activity
BXU06_10810	COG3045	CreA protein
BXU06_10825	COG2132	Multicopper oxidase
BXU06_10835	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BXU06_10870	COG0642	Histidine kinase
BXU06_10875	COG0840	transmembrane signaling receptor activity
BXU06_10885	COG0675	Transposase, IS605 OrfB family
BXU06_10905	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BXU06_10910	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BXU06_10920	COG0284	orotidine-5'-phosphate decarboxylase activity
BXU06_10945	COG2119	membrane
BXU06_10955	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BXU06_10960	COG0504	CTP synthase activity
BXU06_10965	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BXU06_10970	COG0148	phosphopyruvate hydratase activity
BXU06_10975	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BXU06_10980	COG3706	GGDEF domain
BXU06_10985	COG2914	Belongs to the UPF0125 (RnfH) family
BXU06_10990	COG2867	negative regulation of translational initiation
BXU06_10995	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BXU06_11005	COG1301	dicarboxylic acid transport
BXU06_11015	COG0583	DNA-binding transcription factor activity
BXU06_11020	COG0776	regulation of translation
BXU06_11030	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BXU06_11040	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BXU06_11045	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BXU06_11050	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BXU06_11055	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BXU06_11060	COG0196	riboflavin kinase activity
BXU06_11075	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BXU06_11080	COG0175	sulfate reduction
BXU06_11085	COG0583	DNA-binding transcription factor activity
BXU06_11095	COG1648	precorrin-2 dehydrogenase activity
BXU06_11095	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BXU06_11100	COG2010	Cytochrome c
BXU06_11110	COG1845	cytochrome c oxidase, subunit III
BXU06_11140	COG4654	Cytochrome c, class I
BXU06_11145	COG2010	Cytochrome c
BXU06_11205	COG0318	PFAM AMP-dependent synthetase and ligase
BXU06_11220	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BXU06_11225	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BXU06_11230	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
BXU06_11245	COG0850	regulation of cytokinetic process
BXU06_11250	COG2894	cell division
BXU06_11255	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BXU06_11260	COG0583	DNA-binding transcription factor activity
BXU06_11290	COG0459	protein refolding
BXU06_11295	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BXU06_11300	COG0723	plastoquinol--plastocyanin reductase activity
BXU06_11305	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BXU06_11310	COG2857	Cytochrome c1
BXU06_11315	COG0625	glutathione transferase activity
BXU06_11320	COG2969	positive regulation of protein catabolic process
BXU06_11325	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BXU06_11335	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BXU06_11340	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BXU06_11345	COG1534	Rna-binding protein
BXU06_11375	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BXU06_11390	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BXU06_11405	COG0675	Transposase, IS605 OrfB family
BXU06_11420	COG1960	acyl-CoA dehydrogenase activity
BXU06_11435	COG2030	dehydratase
BXU06_11450	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BXU06_11455	COG0583	DNA-binding transcription factor activity
BXU06_11470	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BXU06_11475	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BXU06_11480	COG2833	Protein of unknown function (DUF455)
BXU06_11490	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BXU06_11495	COG1032	radical SAM domain protein
BXU06_11525	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BXU06_11530	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BXU06_11550	COG1309	transcriptional regulator
BXU06_11570	COG2193	ferroxidase activity
BXU06_11580	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BXU06_11585	COG1309	transcriptional regulator
BXU06_11590	COG1902	pentaerythritol trinitrate reductase activity
BXU06_11610	COG2755	lipolytic protein G-D-S-L family
BXU06_11610	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BXU06_11620	COG1028	Short-chain dehydrogenase reductase Sdr
BXU06_11635	COG0037	tRNA processing
BXU06_11640	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BXU06_11645	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BXU06_11665	COG1012	belongs to the aldehyde dehydrogenase family
BXU06_11670	COG2070	2-Nitropropane dioxygenase
BXU06_11685	COG0840	transmembrane signaling receptor activity
BXU06_11700	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BXU06_11705	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BXU06_11725	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BXU06_11735	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BXU06_11740	COG0252	asparaginase activity
BXU06_11750	COG0730	response to heat
BXU06_11795	COG2977	Belongs to the P-Pant transferase superfamily
BXU06_11800	COG1021	2,3-dihydroxybenzoate-AMP ligase
BXU06_11835	COG4771	TonB-dependent receptor
BXU06_11850	COG4771	TonB-dependent receptor
BXU06_11860	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BXU06_11865	COG0406	alpha-ribazole phosphatase activity
BXU06_11870	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BXU06_11890	COG0123	including yeast histone deacetylase and acetoin utilization protein
BXU06_11895	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BXU06_11905	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BXU06_11910	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BXU06_11915	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BXU06_11920	COG0045	succinate-CoA ligase (ADP-forming) activity
BXU06_11920	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BXU06_11920	COG1042	CoA-binding domain protein
BXU06_11925	COG0228	four-way junction DNA binding
BXU06_11930	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BXU06_11935	COG0336	Belongs to the RNA methyltransferase TrmD family
BXU06_11940	COG0335	large ribosomal subunit rRNA binding
BXU06_11945	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BXU06_11950	COG0542	response to heat
BXU06_11955	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BXU06_11965	COG1278	Cold shock
BXU06_11970	COG1278	Cold shock
BXU06_11985	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
BXU06_11990	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BXU06_12025	COG1959	2 iron, 2 sulfur cluster binding
BXU06_12030	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BXU06_12030	COG1017	nitric oxide dioxygenase activity
BXU06_12050	COG0004	ammonium transporteR
BXU06_12070	COG0277	FAD linked oxidase domain protein
BXU06_12080	COG0415	Belongs to the DNA photolyase family
BXU06_12085	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BXU06_12100	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BXU06_12115	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BXU06_12120	COG0438	transferase activity, transferring glycosyl groups
BXU06_12145	COG0367	asparagine synthase
BXU06_12170	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BXU06_12200	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BXU06_12205	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BXU06_12210	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BXU06_12220	COG1560	Kdo2-lipid A biosynthetic process
BXU06_12230	COG1007	ATP synthesis coupled electron transport
BXU06_12245	COG0713	ATP synthesis coupled electron transport
BXU06_12255	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXU06_12260	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BXU06_12265	COG1034	ATP synthesis coupled electron transport
BXU06_12270	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BXU06_12280	COG0649	NAD binding
BXU06_12285	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXU06_12290	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXU06_12295	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BXU06_12305	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BXU06_12310	COG0149	triose-phosphate isomerase activity
BXU06_12320	COG0573	inorganic phosphate transmembrane transporter activity
BXU06_12325	COG0581	inorganic phosphate transmembrane transporter activity
BXU06_12330	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BXU06_12335	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BXU06_12340	COG1196	nuclear chromosome segregation
BXU06_12355	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BXU06_12365	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
BXU06_12370	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BXU06_12380	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BXU06_12385	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BXU06_12390	COG0193	aminoacyl-tRNA hydrolase activity
BXU06_12395	COG0012	GTP binding
BXU06_12410	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BXU06_12430	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BXU06_12450	COG0559	Belongs to the binding-protein-dependent transport system permease family
BXU06_12465	COG0410	ABC transporter
BXU06_12470	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BXU06_12480	COG2226	methyltransferase
BXU06_12490	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BXU06_12495	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BXU06_12500	COG0511	ligase activity, forming carbon-carbon bonds
BXU06_12505	COG0439	Biotin carboxylase
BXU06_12510	COG2264	protein methyltransferase activity
BXU06_12520	COG0473	3-isopropylmalate dehydrogenase activity
BXU06_12525	COG0438	transferase activity, transferring glycosyl groups
BXU06_12585	COG1104	cysteine desulfurase activity
BXU06_12590	COG0822	iron-sulfur transferase activity
BXU06_12600	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BXU06_12605	COG0443	Heat shock 70 kDa protein
BXU06_12615	COG2975	iron-sulfur cluster assembly
BXU06_12620	COG3550	peptidyl-serine autophosphorylation
BXU06_12635	COG1620	l-lactate permease
BXU06_12645	COG1139	Iron-sulfur cluster binding protein
BXU06_12655	COG0247	lactate metabolic process
BXU06_12660	COG2186	Transcriptional regulator
BXU06_12665	COG3135	benzoate transporter
BXU06_12670	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXU06_12675	COG0606	chelatase, subunit chli
BXU06_12690	COG0004	ammonium transporteR
BXU06_12700	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BXU06_12705	COG0586	Pfam SNARE associated Golgi protein
BXU06_12715	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BXU06_12720	COG0501	Belongs to the peptidase M48B family
BXU06_12730	COG2194	sulfuric ester hydrolase activity
BXU06_12735	COG0675	Transposase, IS605 OrfB family
BXU06_12745	COG3327	negative regulation of DNA-templated transcription, initiation
BXU06_12780	COG3077	Addiction module antitoxin, RelB DinJ family
BXU06_12785	COG3041	Addiction module toxin RelE StbE family
BXU06_12795	COG1739	Uncharacterized protein family UPF0029
BXU06_12805	COG4266	Belongs to the allantoicase family
BXU06_12815	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BXU06_12825	COG2351	hydroxyisourate hydrolase activity
BXU06_12875	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BXU06_12880	COG2249	NAD(P)H dehydrogenase (quinone) activity
BXU06_12895	COG5433	transposase activity
BXU06_12900	COG1132	(ABC) transporter
BXU06_12910	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BXU06_12915	COG0741	lytic transglycosylase activity
BXU06_12925	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BXU06_12930	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BXU06_12935	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BXU06_12945	COG3842	ATPase activity
BXU06_12950	COG1176	ABC-type spermidine putrescine transport system, permease component I
BXU06_12955	COG1177	transmembrane transport
BXU06_12975	COG1295	ribonuclease BN
BXU06_12990	COG0745	RESPONSE REGULATOR receiver
BXU06_13035	COG0426	domain, Protein
BXU06_13060	COG0840	transmembrane signaling receptor activity
BXU06_13075	COG4251	negative regulation of phosphorylation
BXU06_13080	COG2205	protein histidine kinase activity
BXU06_13085	COG0784	Response regulator, receiver
BXU06_13140	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
BXU06_13195	COG0716	FMN binding
BXU06_13265	COG0003	Pfam Anion-transporting ATPase
BXU06_13295	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BXU06_13300	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BXU06_13310	COG0140	phosphoribosyl-ATP diphosphatase activity
BXU06_13315	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BXU06_13320	COG0107	imidazoleglycerol-phosphate synthase activity
BXU06_13325	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BXU06_13330	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BXU06_13335	COG0131	Imidazoleglycerol-phosphate dehydratase
BXU06_13340	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BXU06_13360	COG0438	transferase activity, transferring glycosyl groups
BXU06_13365	COG0859	PFAM glycosyl transferase family 9
BXU06_13370	COG0726	polysaccharide deacetylase
BXU06_13375	COG0438	transferase activity, transferring glycosyl groups
BXU06_13380	COG1132	(ABC) transporter
BXU06_13385	COG0697	spore germination
BXU06_13440	COG0823	Involved in the tonB-independent uptake of proteins
BXU06_13490	COG0165	Argininosuccinate lyase
BXU06_13510	COG0418	dihydroorotase activity
BXU06_13540	COG1760	l-serine dehydratase
BXU06_13555	COG3245	cytochrome
BXU06_13565	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BXU06_13570	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BXU06_13580	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BXU06_13605	COG0402	S-adenosylhomocysteine deaminase activity
BXU06_13625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BXU06_13630	COG1116	anion transmembrane transporter activity
BXU06_13645	COG0477	Major facilitator Superfamily
BXU06_13650	COG0583	DNA-binding transcription factor activity
BXU06_13660	COG0408	coproporphyrinogen oxidase activity
BXU06_13680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BXU06_13690	COG0840	transmembrane signaling receptor activity
BXU06_13695	COG0589	response to stress
BXU06_13700	COG1187	pseudouridine synthase activity
BXU06_13705	COG0840	transmembrane signaling receptor activity
BXU06_13720	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BXU06_13725	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BXU06_13740	COG0189	ligase activity
BXU06_13770	COG1505	serine-type exopeptidase activity
BXU06_13775	COG1929	Belongs to the glycerate kinase type-1 family
BXU06_13790	COG1126	abc transporter atp-binding protein
BXU06_13795	COG0765	amino acid transport
BXU06_13800	COG0765	amino acid transport
BXU06_13805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BXU06_13825	COG0745	RESPONSE REGULATOR receiver
BXU06_13830	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BXU06_13835	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BXU06_13840	COG0708	Exodeoxyribonuclease III
BXU06_13845	COG0840	transmembrane signaling receptor activity
BXU06_13850	COG0424	maF-like protein
BXU06_13855	COG1530	ribonuclease E activity
BXU06_13865	COG1451	nucleotide metabolic process
BXU06_13885	COG1858	cytochrome C peroxidase
BXU06_13900	COG3300	MHYT domain
BXU06_13900	COG5001	Diguanylate cyclase
BXU06_13905	COG0772	Belongs to the SEDS family
BXU06_13910	COG0768	penicillin binding
BXU06_13920	COG1792	Involved in formation and maintenance of cell shape
BXU06_13925	COG1077	Cell shape determining protein MreB Mrl
BXU06_13930	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BXU06_13935	COG0154	amidase activity
BXU06_13940	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BXU06_13970	COG0840	transmembrane signaling receptor activity
BXU06_13975	COG2040	homocysteine
BXU06_13980	COG2001	Belongs to the MraZ family
BXU06_13985	COG0275	rRNA processing
BXU06_13990	COG3116	cell division
BXU06_14000	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BXU06_14005	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BXU06_14010	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BXU06_14015	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BXU06_14020	COG0772	Belongs to the SEDS family
BXU06_14025	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BXU06_14030	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BXU06_14035	COG1181	Belongs to the D-alanine--D-alanine ligase family
BXU06_14040	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BXU06_14055	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BXU06_14060	COG0315	cyclic pyranopterin monophosphate synthase activity
BXU06_14070	COG3039	Transposase
BXU06_14165	COG1902	pentaerythritol trinitrate reductase activity
BXU06_14165	COG0446	pyridine nucleotide-disulphide oxidoreductase
BXU06_14170	COG2197	response regulator
BXU06_14175	COG0675	Transposase, IS605 OrfB family
BXU06_14180	COG2198	Histidine kinase
BXU06_14180	COG2205	protein histidine kinase activity
BXU06_14180	COG0784	Response regulator, receiver
BXU06_14180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BXU06_14190	COG0067	glutamate synthase
BXU06_14190	COG0069	glutamate synthase activity
BXU06_14190	COG0070	glutamate synthase
BXU06_14195	COG0493	'glutamate synthase
BXU06_14200	COG0523	cobalamin synthesis protein
BXU06_14205	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BXU06_14210	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BXU06_14215	COG0210	DNA helicase
BXU06_14225	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BXU06_14230	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BXU06_14235	COG2200	EAL domain
BXU06_14235	COG2771	luxR family
BXU06_14255	COG4208	sulfate ABC transporter
BXU06_14260	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BXU06_14280	COG0583	DNA-binding transcription factor activity
BXU06_14295	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BXU06_14310	COG0675	Transposase, IS605 OrfB family
BXU06_14315	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BXU06_14320	COG1120	ATPase activity
BXU06_14325	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BXU06_14330	COG4558	Periplasmic binding protein
BXU06_14335	COG3720	iron ion transport
BXU06_14380	COG5433	transposase activity
BXU06_14385	COG2801	Transposase and inactivated derivatives
BXU06_14415	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BXU06_14415	COG0189	ligase activity
BXU06_14440	COG2201	protein-glutamate methylesterase activity
BXU06_14445	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BXU06_14455	COG0835	chemotaxis
BXU06_14465	COG0643	Histidine kinase
BXU06_14465	COG2198	Histidine kinase
BXU06_14490	COG0642	Histidine kinase
BXU06_14495	COG0675	Transposase, IS605 OrfB family
BXU06_14515	COG0675	Transposase, IS605 OrfB family
BXU06_14520	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BXU06_14525	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BXU06_14530	COG1280	lysine exporter protein (LysE YggA)
BXU06_14535	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BXU06_14565	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BXU06_14580	COG3706	GGDEF domain
BXU06_14585	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BXU06_14590	COG0440	acetolactate synthase activity
BXU06_14595	COG0028	Belongs to the TPP enzyme family
BXU06_14620	COG1999	signal sequence binding
BXU06_14625	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
BXU06_14630	COG0688	phosphatidylethanolamine metabolic process
BXU06_14635	COG1183	phosphatidylcholine synthase activity
BXU06_14640	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BXU06_14650	COG0604	alcohol dehydrogenase
BXU06_14655	COG1309	transcriptional regulator
BXU06_14695	COG0138	bifunctional purine biosynthesis protein purh
BXU06_14730	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BXU06_14735	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BXU06_14740	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BXU06_14745	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BXU06_14750	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BXU06_14755	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BXU06_14760	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BXU06_14765	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BXU06_14775	COG0356	it plays a direct role in the translocation of protons across the membrane
BXU06_14790	COG1192	Involved in chromosome partitioning
BXU06_14795	COG0357	Ribosomal RNA small subunit methyltransferase G
BXU06_14800	COG0445	tRNA wobble uridine modification
BXU06_14825	COG1294	oxidase, subunit
BXU06_14845	COG1720	tRNA m6t6A37 methyltransferase activity
BXU06_14855	COG2199	diguanylate cyclase activity
BXU06_14855	COG2200	EAL domain
BXU06_14855	COG3287	FIST C domain
BXU06_14860	COG2823	Periplasmic or secreted lipoprotein
BXU06_14865	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
BXU06_14870	COG0792	nuclease activity
BXU06_14875	COG3107	peptidoglycan biosynthetic process
BXU06_14900	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BXU06_14910	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BXU06_14945	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BXU06_14950	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BXU06_14965	COG0640	Transcriptional regulator
BXU06_14975	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BXU06_14980	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BXU06_14990	COG1522	sequence-specific DNA binding
BXU06_14995	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BXU06_15000	COG5002	protein histidine kinase activity
BXU06_15000	COG5001	Diguanylate cyclase
BXU06_15035	COG2197	response regulator
BXU06_15075	COG0826	peptidase U32
BXU06_15085	COG2814	Major facilitator Superfamily
BXU06_15130	COG0789	Transcriptional regulator
BXU06_15135	COG1132	(ABC) transporter
BXU06_15165	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
BXU06_15165	COG2199	diguanylate cyclase activity
BXU06_15180	COG1965	Belongs to the frataxin family
BXU06_15185	COG1238	metal cluster binding
BXU06_15190	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BXU06_15195	COG1126	abc transporter atp-binding protein
BXU06_15200	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BXU06_15220	COG0824	Thioesterase
BXU06_15235	COG0783	Belongs to the Dps family
BXU06_15240	COG1872	DUF167
BXU06_15255	COG3030	protein affecting phage T7 exclusion by the F plasmid
BXU06_15260	COG1324	tolerance protein
BXU06_15270	COG0697	spore germination
BXU06_15295	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BXU06_15310	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
BXU06_15315	COG0540	Belongs to the ATCase OTCase family
BXU06_15330	COG2319	Wd-40 repeat
BXU06_15345	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BXU06_15355	COG0174	glutamine synthetase
BXU06_15360	COG1648	precorrin-2 dehydrogenase activity
BXU06_15360	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BXU06_15385	COG0142	geranyltranstransferase activity
BXU06_15410	COG0859	PFAM glycosyl transferase family 9
BXU06_15415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BXU06_15455	COG2205	protein histidine kinase activity
BXU06_15460	COG0745	RESPONSE REGULATOR receiver
BXU06_15470	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BXU06_15475	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BXU06_15485	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BXU06_15495	COG0463	Glycosyl transferase, family 2
BXU06_15500	COG0859	PFAM glycosyl transferase family 9
BXU06_15505	COG1519	Transferase
BXU06_15525	COG0352	thiamine-phosphate diphosphorylase activity
BXU06_15530	COG0351	phosphomethylpyrimidine kinase
BXU06_15535	COG1773	rubredoxin
BXU06_15550	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BXU06_15575	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
BXU06_15590	COG1794	racemase activity, acting on amino acids and derivatives
BXU06_15630	COG1116	anion transmembrane transporter activity
BXU06_15635	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BXU06_15640	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BXU06_15650	COG0653	protein targeting
BXU06_15660	COG0840	transmembrane signaling receptor activity
BXU06_15710	COG2814	Major facilitator Superfamily
BXU06_15715	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BXU06_15725	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BXU06_15730	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BXU06_15735	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BXU06_15785	COG2336	PFAM SpoVT AbrB
BXU06_15790	COG2337	Toxic component of a toxin-antitoxin (TA) module
BXU06_15825	COG2944	sequence-specific DNA binding
BXU06_15870	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BXU06_15875	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BXU06_15890	COG0662	Cupin 2, conserved barrel domain protein
BXU06_15890	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BXU06_15925	COG1091	dTDP-4-dehydrorhamnose reductase activity
BXU06_15935	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BXU06_15940	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
BXU06_15945	COG0126	phosphoglycerate kinase activity
BXU06_15955	COG1280	lysine exporter protein (LysE YggA)
BXU06_15965	COG0582	viral genome integration into host DNA
BXU06_16025	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BXU06_16030	COG0242	peptide deformylase activity
BXU06_16065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BXU06_16075	COG1538	Outer membrane efflux protein
BXU06_16080	COG1027	Aspartate ammonia-lyase
BXU06_16100	COG1116	anion transmembrane transporter activity
BXU06_16105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BXU06_16110	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BXU06_16115	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BXU06_16120	COG0431	NADPH-dependent FMN reductase
BXU06_16125	COG3237	CsbD-like
BXU06_16155	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BXU06_16160	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BXU06_16165	COG1045	serine acetyltransferase
BXU06_16180	COG5433	transposase activity
BXU06_16195	COG0411	ABC transporter
BXU06_16210	COG0446	pyridine nucleotide-disulphide oxidoreductase
BXU06_16215	COG3384	dioxygenase
BXU06_16235	COG4638	Rieske (2fe-2S)
BXU06_16240	COG0583	DNA-binding transcription factor activity
BXU06_16245	COG2267	carboxylic ester hydrolase activity
BXU06_16250	COG3971	2-oxopent-4-enoate hydratase activity
BXU06_16255	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BXU06_16260	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BXU06_16265	COG3813	Protein conserved in bacteria
BXU06_16295	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BXU06_16300	COG0840	transmembrane signaling receptor activity
BXU06_16310	COG2207	Transcriptional regulator
BXU06_16330	COG1538	Outer membrane efflux protein
BXU06_16345	COG1309	transcriptional regulator
BXU06_16350	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BXU06_16370	COG0741	lytic transglycosylase activity
BXU06_16380	COG3158	transport of potassium into the cell
BXU06_16425	COG0745	RESPONSE REGULATOR receiver
BXU06_16435	COG0697	spore germination
BXU06_16440	COG1522	sequence-specific DNA binding
BXU06_16455	COG0557	exoribonuclease II activity
BXU06_16465	COG2922	Belongs to the Smg family
BXU06_16470	COG0758	DNA mediated transformation
BXU06_16470	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BXU06_16475	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BXU06_16480	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BXU06_16495	COG1187	pseudouridine synthase activity
BXU06_16500	COG3781	membrane
BXU06_16505	COG0697	spore germination
BXU06_16510	COG5433	transposase activity
BXU06_16525	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BXU06_16535	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BXU06_16545	COG3150	esterase
BXU06_16550	COG1448	Aminotransferase
BXU06_16555	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BXU06_16560	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BXU06_16565	COG1333	cytochrome c biogenesis protein
BXU06_16575	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BXU06_16590	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BXU06_16595	COG1040	competence protein
BXU06_16600	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BXU06_16605	COG0156	8-amino-7-oxononanoate synthase activity
BXU06_16630	COG0762	integral membrane protein
BXU06_16635	COG4654	Cytochrome c, class I
BXU06_16640	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BXU06_16645	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BXU06_16670	COG0314	molybdopterin synthase activity
BXU06_16675	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
BXU06_16695	COG1136	(ABC) transporter
BXU06_16710	COG0840	transmembrane signaling receptor activity
BXU06_16725	COG0584	glycerophosphoryl diester phosphodiesterase
BXU06_16730	COG0617	tRNA 3'-terminal CCA addition
BXU06_16745	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BXU06_16750	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
BXU06_16760	COG0535	radical SAM domain protein
BXU06_16765	COG2197	response regulator
BXU06_16805	COG3550	peptidyl-serine autophosphorylation
BXU06_16845	COG1802	Transcriptional regulator
BXU06_16880	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BXU06_16885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BXU06_16910	COG4783	chaperone-mediated protein folding
BXU06_16925	COG2391	methyltransferase activity
BXU06_16935	COG0640	Transcriptional regulator
BXU06_16945	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BXU06_16950	COG1984	allophanate hydrolase subunit 2
BXU06_16955	COG0288	reversible hydration of carbon dioxide
BXU06_16960	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BXU06_16965	COG0799	negative regulation of ribosome biogenesis
BXU06_16970	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BXU06_16975	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BXU06_16985	COG0840	transmembrane signaling receptor activity
BXU06_16990	COG0339	signal peptide processing
BXU06_16995	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BXU06_17010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BXU06_17025	COG0745	RESPONSE REGULATOR receiver
BXU06_17030	COG1414	Transcriptional regulator
BXU06_17035	COG3384	dioxygenase
BXU06_17045	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BXU06_17055	COG3971	2-oxopent-4-enoate hydratase activity
BXU06_17060	COG4569	acetaldehyde dehydrogenase (acetylating) activity
BXU06_17065	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BXU06_17070	COG0411	ABC transporter
BXU06_17085	COG2267	carboxylic ester hydrolase activity
BXU06_17095	COG0840	transmembrane signaling receptor activity
BXU06_17110	COG2814	Major facilitator Superfamily
BXU06_17115	COG0840	transmembrane signaling receptor activity
BXU06_17120	COG1012	belongs to the aldehyde dehydrogenase family
BXU06_17125	COG0531	amino acid
BXU06_17140	COG0675	Transposase, IS605 OrfB family
BXU06_17145	COG2207	Transcriptional regulator
BXU06_17165	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BXU06_17170	COG1074	ATP-dependent DNA helicase activity
BXU06_17175	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BXU06_17180	COG2199	diguanylate cyclase activity
BXU06_17180	COG2200	EAL domain
BXU06_17185	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BXU06_17190	COG3047	cAMP biosynthetic process
BXU06_17200	COG0009	L-threonylcarbamoyladenylate synthase
BXU06_17220	COG3039	Transposase
BXU06_17230	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BXU06_17235	COG0706	membrane insertase activity
BXU06_17240	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BXU06_17245	COG0594	ribonuclease P activity
BXU06_17250	COG0230	Belongs to the bacterial ribosomal protein bL34 family