locus-tag	class	description
D1816_00015	ENOG4105C1J	atp-dependent rna helicase
D1816_00030	ENOG4105CRQ	synthase (Component I)
D1816_00040	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
D1816_00070	ENOG4105BZU	Histidine kinase
D1816_00100	ENOG4105C27	TonB-dependent Receptor Plug
D1816_00120	ENOG4107URF	beta-phospho-glucomutase
D1816_00130	ENOG4108IUK	alpha amylase, catalytic
D1816_00135	ENOG4105CG3	alpha amylase, catalytic region
D1816_00140	ENOG4105CTQ	phosphohexokinase
D1816_00145	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D1816_00170	ENOG4107QZF	nitrite reductase NADPH large subunit
D1816_00180	ENOG4105WH1	Two component transcriptional regulator luxr family
D1816_00190	ENOG4105D7T	ABC transporter
D1816_00195	ENOG4105DG7	nitrate ABC transporter
D1816_00200	ENOG4105D7T	ABC transporter
D1816_00205	ENOG4105D7T	ABC transporter
D1816_00210	ENOG4107RNU	major facilitator superfamily MFS_1
D1816_00215	ENOG4105CRE	cytochrome C
D1816_00220	ENOG4105CRE	cytochrome C
D1816_00235	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
D1816_00255	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
D1816_00280	ENOG4105CN1	protease
D1816_00290	ENOG4105BZU	Histidine kinase
D1816_00310	ENOG4105C9K	Endothelin-converting enzyme 1
D1816_00320	ENOG4105CFH	Aspartokinase
D1816_00345	ENOG4105C0P	Mg chelatase subunit ChlI
D1816_00360	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
D1816_00370	ENOG4105P4J	Allophanate hydrolase, subunit 1
D1816_00390	ENOG4105ENE	Histidine kinase
D1816_00395	ENOG4105WH1	Two component transcriptional regulator luxr family
D1816_00400	ENOG4105C01	Dihydroxy-acid dehydratase
D1816_00405	ENOG4105C7K	acetolactate synthase
D1816_00415	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
D1816_00420	ENOG4105C7B	Threonine dehydratase
D1816_00430	ENOG4108UHU	Aldolase
D1816_00440	ENOG4105CHR	reductase
D1816_00445	ENOG4105DPW	Major facilitator superfamily MFS_1
D1816_00450	ENOG4107YCY	Transcriptional regulator
D1816_00465	ENOG4105TT1	Ragb susd domain-containing protein
D1816_00470	ENOG4105C27	TonB-dependent Receptor Plug
D1816_00480	ENOG4105EY3	heparinase II III family protein
D1816_00510	ENOG4105CDH	Citrulline--aspartate ligase
D1816_00515	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
D1816_00520	ENOG4105II7	pyrroline-5-carboxylate reductase
D1816_00525	ENOG4105C8Y	Acetylornithine aminotransferase
D1816_00535	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
D1816_00540	ENOG4107REN	Carbamoyltransferase
D1816_00545	ENOG4107T6X	nag kinase
D1816_00555	ENOG4105CH7	arginosuccinase
D1816_00560	ENOG4107Y7Q	pfkb domain protein
D1816_00595	ENOG4107QN1	sodium solute
D1816_00605	ENOG4105BZU	Histidine kinase
D1816_00610	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D1816_00620	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
D1816_00630	ENOG4105C5H	ABC transporter
D1816_00650	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
D1816_00670	ENOG4107QX3	carboxylase
D1816_00675	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
D1816_00680	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
D1816_00715	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D1816_00740	ENOG4105EAA	nucleoside
D1816_00765	ENOG41075H3	AraC family transcriptional regulator
D1816_00780	ENOG4107RAQ	aminopeptidase
D1816_00805	ENOG4107QWR	cellulase (EC 3.2.1.4)
D1816_00810	ENOG4105BZU	Histidine kinase
D1816_00840	ENOG4105CPQ	Dehydrogenase
D1816_00850	ENOG4105CHR	reductase
D1816_00855	ENOG4105DIA	mandelate racemase muconate lactonizing
D1816_00865	ENOG4105CNG	UPF0061 protein
D1816_00875	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
D1816_00890	ENOG4105ENE	Histidine kinase
D1816_00905	ENOG4106432	Mediates binding to human platelets, possibly through a receptor-ligand interaction. Probably associated with virulence in endovascular infection (By similarity)
D1816_00930	ENOG4105EUJ	GTP cyclohydrolase i
D1816_00940	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D1816_00955	ENOG4105CGH	5'-nucleotidase
D1816_00960	ENOG4105CGH	5'-nucleotidase
D1816_00965	ENOG4105CKI	cobalamin synthesis protein
D1816_01015	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
D1816_01040	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
D1816_01055	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
D1816_01075	ENOG4108YZA	Nitrogen regulatory protein pii
D1816_01140	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
D1816_01150	ENOG4105EHG	Permease protein
D1816_01165	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
D1816_01175	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
D1816_01185	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D1816_01220	ENOG4107QTF	adenylosuccinate lyase
D1816_01235	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
D1816_01250	ENOG4105BZU	Histidine kinase
D1816_01280	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
D1816_01295	ENOG4105C1J	atp-dependent rna helicase
D1816_01310	ENOG4108ETT	Dehydrogenase
D1816_01315	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
D1816_01325	ENOG4105C5H	ABC transporter
D1816_01415	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
D1816_01420	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D1816_01425	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D1816_01430	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
D1816_01460	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
D1816_01470	ENOG4105EJQ	L-serine dehydratase
D1816_01475	ENOG4105CFG	Acts as a chaperone (By similarity)
D1816_01485	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
D1816_01490	ENOG4108ZYK	Acyl carrier protein phosphodiesterase
D1816_01500	ENOG4107QKV	phosphomannomutase
D1816_01525	ENOG4105CEY	Amp-dependent synthetase and ligase
D1816_01550	ENOG4105D1S	lipid A biosynthesis
D1816_01565	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1816_01590	ENOG4108RMU	ferritin dps family protein
D1816_01595	ENOG41081VB	Hydrolase
D1816_01600	ENOG4105CN9	Peptidase m42 family protein
D1816_01635	ENOG4108UT2	hemolysin iii
D1816_01645	ENOG4105BZU	Histidine kinase
D1816_01680	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
D1816_01685	ENOG4105EMN	RNA polymerase sigma factor
D1816_01695	ENOG4105C8Y	Acetylornithine aminotransferase
D1816_01745	ENOG4107QI6	Cysteine desulfurase
D1816_01755	ENOG4105DR5	peptidase
D1816_01760	ENOG4105GH9	galactofuranosyltransferase
D1816_01765	ENOG4105D5D	udp-galactopyranose mutase
D1816_01785	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
D1816_01855	ENOG4105C6K	Malic enzyme
D1816_01860	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
D1816_01885	ENOG4105CYP	glycoside hydrolase, family
D1816_01915	ENOG41082YX	Transcriptional regulator, arsr family
D1816_01925	ENOG41090R7	Ferric uptake
D1816_01940	ENOG4105FQP	Beta-lactamase
D1816_01960	ENOG4108V1U	phospholipid-binding protein
D1816_01980	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
D1816_02040	ENOG4105CHR	reductase
D1816_02045	ENOG4105VSH	4-oxalocrotonate tautomerase
D1816_02105	ENOG4105NF4	modulator of drug activity
D1816_02115	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D1816_02160	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
D1816_02195	ENOG41086D8	Transcriptional regulator
D1816_02315	ENOG4105EMN	RNA polymerase sigma factor
D1816_02600	ENOG4105KAC	Antibiotic biosynthesis monooxygenase
D1816_02680	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D1816_02700	ENOG4108JA5	May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs (By similarity)
D1816_02705	ENOG4105DY9	regulatoR
D1816_02720	ENOG4105CD8	aminopeptidase N
D1816_02760	ENOG4105CBC	glutamate synthase
D1816_02765	ENOG4105CH2	amidohydrolase
D1816_02775	ENOG4107G87	m6 family metalloprotease domain protein
D1816_02790	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
D1816_02795	ENOG410874W	AraC family transcriptional regulator
D1816_02845	ENOG4105E1F	short-chain dehydrogenase reductase
D1816_02850	ENOG4105C27	TonB-dependent Receptor Plug
D1816_02855	ENOG4105TT1	Ragb susd domain-containing protein
D1816_02875	ENOG4105EW9	transcriptional regulator AsnC family
D1816_02880	ENOG4105C28	cystathionine
D1816_02895	ENOG4105C9Q	fumarate hydratase class II
D1816_02900	ENOG4107RNH	Outer membrane receptor FepA
D1816_02905	ENOG4105K89	arsenate reductase
D1816_02995	ENOG41080WS	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
D1816_03010	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D1816_03090	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
D1816_03100	ENOG4105CSM	endonuclease III
D1816_03105	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1816_03120	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
D1816_03135	ENOG4105CJQ	hydrolase, family 31
D1816_03185	ENOG4105CD3	dihydroorotase
D1816_03210	ENOG4105C1J	atp-dependent rna helicase
D1816_03230	ENOG4105DZ0	fad dependent oxidoreductase
D1816_03235	ENOG4105BZU	Histidine kinase
D1816_03255	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D1816_03265	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
D1816_03270	ENOG4105EUJ	GTP cyclohydrolase i
D1816_03320	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
D1816_03330	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
D1816_03345	ENOG4107XM9	(LipO)protein
D1816_03355	ENOG4107T9C	Alpha amylase catalytic region
D1816_03360	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
D1816_03365	ENOG4107W2A	UPF0173 metal-dependent hydrolase
D1816_03415	ENOG4105DY9	regulatoR
D1816_03420	ENOG4108HRK	Histidine kinase
D1816_03425	ENOG4107QX3	carboxylase
D1816_03445	ENOG4105C5H	ABC transporter
D1816_03470	ENOG4105VEQ	Cold shock protein
D1816_03475	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
D1816_03520	ENOG4105DY9	regulatoR
D1816_03525	ENOG4108HRK	Histidine kinase
D1816_03535	ENOG4105D8V	Glucose sorbosone dehydrogenase
D1816_03585	ENOG4105C27	TonB-dependent Receptor Plug
D1816_03590	ENOG4105C27	TonB-dependent Receptor Plug
D1816_03620	ENOG4108Q35	Adenylate
D1816_03655	ENOG4105EUB	pirin domain protein
D1816_03665	ENOG4105D29	Helix-turn-helix type 11 domain protein
D1816_03680	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
D1816_03685	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
D1816_03690	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
D1816_03695	ENOG4105BZP	glycoside hydrolase 15-related
D1816_03700	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
D1816_03730	ENOG4105ERG	peptidase m48, ste24p
D1816_03745	ENOG4105UYK	outer membrane protein a
D1816_03760	ENOG41065KQ	synthase
D1816_03765	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
D1816_03775	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
D1816_03785	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D1816_03790	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
D1816_03820	ENOG4107TPS	domain protein
D1816_03825	ENOG4105C72	UPF0176 protein
D1816_03835	ENOG4105D3R	alkyl hydroperoxide reductase
D1816_03870	ENOG4105C2C	drug resistance transporter, Bcr CflA
D1816_03920	ENOG4108RCM	Nitroreductase
D1816_03925	ENOG4105KVH	Transcriptional regulator
D1816_03945	ENOG4105E39	Enoyl-CoA hydratase
D1816_03970	ENOG4108HRK	Histidine kinase
D1816_04050	ENOG4105DY9	regulatoR
D1816_04055	ENOG4108HRK	Histidine kinase
D1816_04075	ENOG4105DY9	regulatoR
D1816_04080	ENOG4108HRK	Histidine kinase
D1816_04095	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
D1816_04105	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
D1816_04135	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
D1816_04155	ENOG4108KF3	Electron transport protein SCO1 SenC
D1816_04160	ENOG4108M1A	Chitin-binding protein
D1816_04200	ENOG4108JJA	ABC, transporter
D1816_04255	ENOG4105ID8	Transcriptional regulator, ARAC family
D1816_04260	ENOG4105CHR	reductase
D1816_04285	ENOG4105DR5	peptidase
D1816_04295	ENOG4105DY9	regulatoR
D1816_04340	ENOG4108NEV	two component transcriptional regulator, LytTR family
D1816_04350	ENOG4105DY9	regulatoR
D1816_04395	ENOG4105DZ2	Transcriptional regulator
D1816_04405	ENOG4108AEY	RNA polymerase sigma factor
D1816_04415	ENOG4107S1E	Beta-lactamase
D1816_04490	ENOG4105DA5	(ABC) transporter
D1816_04495	ENOG4108HRK	Histidine kinase
D1816_04500	ENOG4105DY9	regulatoR
D1816_04515	ENOG4105J8Z	peptidase S8 and S53, subtilisin, kexin, sedolisin
D1816_04540	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
D1816_04545	ENOG4105BZ1	(ABC) transporter
D1816_04555	ENOG4108NEV	two component transcriptional regulator, LytTR family
D1816_04560	ENOG4108HRK	Histidine kinase
D1816_04570	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
D1816_04580	ENOG4108RG0	uracil-dna glycosylase
D1816_04600	ENOG4105VEQ	Cold shock protein
D1816_04605	ENOG4105C1J	atp-dependent rna helicase
D1816_04610	ENOG4105C1J	atp-dependent rna helicase
D1816_04675	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
D1816_04705	ENOG4105DY9	regulatoR
D1816_04710	ENOG4105CHR	reductase
D1816_04715	ENOG4105C26	Dehydrogenase
D1816_04875	ENOG4105BZU	Histidine kinase
D1816_04895	ENOG4105DR4	Methyltransferase
D1816_04900	ENOG4105WAB	arsR family transcriptional regulator
D1816_04905	ENOG4105JAB	phenazine biosynthesis protein, phzf family
D1816_04910	ENOG4108JA2	transcriptioN-repair coupling factor
D1816_04920	ENOG4105E0X	reductase
D1816_04925	ENOG4105E0X	reductase
D1816_04935	ENOG4107QN2	dihydrolipoyl dehydrogenase
D1816_04960	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D1816_04980	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
D1816_04990	ENOG4107RDY	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
D1816_05000	ENOG4105D98	threonine synthase
D1816_05015	ENOG4105D7Z	glutathione synthase
D1816_05030	ENOG4107VIJ	nudix hydrolase
D1816_05040	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
D1816_05055	ENOG4105C27	TonB-dependent Receptor Plug
D1816_05075	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
D1816_05085	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
D1816_05095	ENOG4105C27	TonB-dependent Receptor Plug
D1816_05105	ENOG4105DY8	decarboxylase
D1816_05110	ENOG4106NZI	LysR family Transcriptional regulator
D1816_05120	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
D1816_05125	ENOG4105C6Z	Gluconate
D1816_05135	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
D1816_05140	ENOG4108ZIS	hydrolase, family 16
D1816_05160	ENOG4105CQB	FAD linked oxidase domain protein
D1816_05180	ENOG4105CPK	Glycosyl transferase (Group 1
D1816_05190	ENOG4105C6E	dna polymerase iii
D1816_05220	ENOG4105CEY	Amp-dependent synthetase and ligase
D1816_05250	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
D1816_05265	ENOG4105UYK	outer membrane protein a
D1816_05270	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
D1816_05280	ENOG4105MH8	Thioredoxin disulfide isomerase
D1816_05290	ENOG4105CXT	aspartate transcarbamylase
D1816_05295	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
D1816_05300	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
D1816_05310	ENOG4105CDV	Ompa motb domain protein
D1816_05325	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
D1816_05330	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
D1816_05340	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
D1816_05350	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
D1816_05355	ENOG4105CIH	Imidazole acetol-phosphate transaminase
D1816_05360	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
D1816_05370	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
D1816_05380	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
D1816_05400	ENOG4105CHR	reductase
D1816_05405	ENOG4105C1V	Peptidase, M16
D1816_05410	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
D1816_05420	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D1816_05425	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
D1816_05430	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D1816_05435	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D1816_05440	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D1816_05445	ENOG4105DCI	Phosphohydrolase
D1816_05450	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1816_05455	ENOG4105K8N	protein family UPF0079, ATPase
D1816_05475	ENOG4105XDF	Protein of unknown function (DUF1272)
D1816_05490	ENOG4105C27	TonB-dependent Receptor Plug
D1816_05525	ENOG4105D49	3-dehydroquinate synthase
D1816_05535	ENOG4105C8P	)-transporter
D1816_05550	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
D1816_05555	ENOG4108URH	decarboxylase
D1816_05565	ENOG4105CPP	Dehydrogenase, E1 component
D1816_05595	ENOG4105QNR	S1 RNA binding domain protein
D1816_05605	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
D1816_05610	ENOG4105E4F	Isochorismate synthase
D1816_05615	ENOG4105KA0	thioesterase Superfamily protein
D1816_05655	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
D1816_05660	ENOG4108VVK	transcriptional Regulator, AsnC
D1816_05680	ENOG4105EE5	Membrane protein terC
D1816_05690	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
D1816_05715	ENOG4105DF5	DNA topoisomerase IV, subunit A
D1816_05725	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
D1816_05730	ENOG4105DQ4	alcohol dehydrogenase
D1816_05745	ENOG4108YI3	3-hydroxyacyl-CoA-acyl carrier protein transferase
D1816_05750	ENOG4105BZU	Histidine kinase
D1816_05760	ENOG4105C3G	gtp-binding protein
D1816_05770	ENOG4107RNH	Outer membrane receptor FepA
D1816_05775	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D1816_05780	ENOG4105CUY	Mechanosensitive ion channel
D1816_05790	ENOG4105CTJ	Metal Dependent Phosphohydrolase
D1816_05795	ENOG4105CHU	acetyl-coa acetyltransferase
D1816_05800	ENOG4107SN7	NLP P60 protein
D1816_05830	ENOG41090PH	Protease synthase and sporulation negative regulatory protein pai 1
D1816_05840	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
D1816_05845	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
D1816_05865	ENOG4105D7W	serine acetyltransferase
D1816_05870	ENOG4105C6T	cysteine synthase
D1816_05875	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
D1816_05880	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D1816_05895	ENOG4108RPX	mosc domain containing protein
D1816_05905	ENOG4108I7Y	domain protein
D1816_05915	ENOG4105CAT	Cytidine monophosphate kinase
D1816_05925	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
D1816_05970	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
D1816_05975	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
D1816_06000	ENOG4105D7W	serine acetyltransferase
D1816_06005	ENOG4105D3Q	Sugar transferase
D1816_06025	ENOG4105D3Q	Sugar transferase
D1816_06055	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
D1816_06065	ENOG4108KMV	Glycosyl transferase (Group 1
D1816_06070	ENOG4107SJB	teichoic acid biosynthesis
D1816_06085	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
D1816_06105	ENOG4107STW	synthase
D1816_06110	ENOG4105CG5	Glycosyl transferase (Group 1
D1816_06130	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
D1816_06140	ENOG4105K64	Glycosyl transferase, family 2
D1816_06150	ENOG4107T8Q	Glycosyl transferase (Group 1
D1816_06155	ENOG4107QQG	Dehydrogenase
D1816_06160	ENOG4108IAJ	Nad-dependent epimerase dehydratase
D1816_06165	ENOG4105CPP	Dehydrogenase, E1 component
D1816_06185	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
D1816_06200	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
D1816_06205	ENOG4105C98	muts2 protein
D1816_06220	ENOG4105EE0	oxidoreductase
D1816_06230	ENOG4105VZ8	Transcriptional regulator
D1816_06240	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
D1816_06255	ENOG4105CHR	reductase
D1816_06260	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
D1816_06275	ENOG4107RSM	transcriptional regulator
D1816_06280	ENOG4105C84	Histidine ammonia-lyase
D1816_06290	ENOG4105CGP	Urocanate hydratase
D1816_06295	ENOG41088SP	formiminoglutamate hydrolase
D1816_06305	ENOG4105VEQ	Cold shock protein
D1816_06315	ENOG4105CHR	reductase
D1816_06320	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
D1816_06325	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
D1816_06330	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
D1816_06345	ENOG4105C1G	acyl-Coa dehydrogenase
D1816_06350	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
D1816_06355	ENOG4105CSU	acyl-Coa dehydrogenase
D1816_06365	ENOG4105BZU	Histidine kinase
D1816_06370	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
D1816_06390	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
D1816_06395	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
D1816_06410	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D1816_06415	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
D1816_06420	ENOG4105K70	DNA-binding protein
D1816_06430	ENOG4105F0I	Aminotransferase
D1816_06470	ENOG4105CUT	histidyl-tRNA synthetase
D1816_06475	ENOG4107RBB	ABC transporter, permease
D1816_06490	ENOG4108KPZ	tonB-dependent Receptor
D1816_06495	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
D1816_06500	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
D1816_06505	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
D1816_06510	ENOG4108NEV	two component transcriptional regulator, LytTR family
D1816_06515	ENOG4108NEV	two component transcriptional regulator, LytTR family
D1816_06520	ENOG4105C25	Primosomal protein n'
D1816_06545	ENOG4107U9T	Pfam:Ribonuclease_BN
D1816_06550	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
D1816_06555	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
D1816_06565	ENOG4108Z03	MAF-like protein
D1816_06580	ENOG4105KZX	Pterin carbinolamine dehydratase
D1816_06585	ENOG4105CDY	transcriptional regulatory protein
D1816_06605	ENOG4107RJC	Iron-containing alcohol dehydrogenase
D1816_06610	ENOG4105C7H	Helicase, RecD TraA family
D1816_06635	ENOG4107QM2	Aldo Keto reductase
D1816_06640	ENOG4105D17	glycoside hydrolase, family 3 domain protein
D1816_06650	ENOG4105DF6	Fe-S oxidoreductase
D1816_06660	ENOG4105DF6	Fe-S oxidoreductase
D1816_06665	ENOG4107KIA	Virulence factor Mce family protein
D1816_06670	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
D1816_06695	ENOG4108Z5K	methylglyoxal synthase
D1816_06700	ENOG4105CTQ	phosphohexokinase
D1816_06710	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
D1816_06750	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
D1816_06770	ENOG4105EUZ	Beta-lactamase domain protein
D1816_06785	ENOG4105KME	endoribonuclease L-psp
D1816_06810	ENOG4107S9F	NmrA family
D1816_06835	ENOG4105FQP	Beta-lactamase
D1816_06900	ENOG4108Z0R	Transferase
D1816_06945	ENOG4105CRE	cytochrome C
D1816_06960	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
D1816_06970	ENOG4105DFD	Na H antiporter
D1816_06980	ENOG4108RCM	Nitroreductase
D1816_06985	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
D1816_06990	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
D1816_07005	ENOG4105CNU	cell division protein FtsK
D1816_07015	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
D1816_07030	ENOG4105D3R	alkyl hydroperoxide reductase
D1816_07035	ENOG4105BZU	Histidine kinase
D1816_07040	ENOG4105C28	cystathionine
D1816_07045	ENOG4105FJR	Lmbe family
D1816_07055	ENOG4105IIU	Aminopeptidase
D1816_07070	ENOG4108JA0	Oxidoreductase, FAD NAD(P)-binding domain protein
D1816_07090	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
D1816_07100	ENOG4105W4W	Transcriptional regulator
D1816_07120	ENOG4106N3A	copper homeostasis protein cutc
D1816_07145	ENOG4105C27	TonB-dependent Receptor Plug
D1816_07190	ENOG4105CWX	Alpha-1,2-mannosidase
D1816_07205	ENOG4105CKB	glycosidase
D1816_07215	ENOG4105CWX	Alpha-1,2-mannosidase
D1816_07225	ENOG4105DY9	regulatoR
D1816_07230	ENOG4105BZU	Histidine kinase
D1816_07235	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D1816_07240	ENOG4105C1J	atp-dependent rna helicase
D1816_07260	ENOG4107QWK	SAICAR synthetase
D1816_07265	ENOG4105C9A	Phoh family
D1816_07285	ENOG4105E0A	ABC, transporter
D1816_07295	ENOG4105CGY	Dna recombination protein
D1816_07315	ENOG4108S4H	thioesterase Superfamily protein
D1816_07325	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
D1816_07330	ENOG4105VG0	50S ribosomal protein l34
D1816_07365	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
D1816_07370	ENOG4108J59	Extracellular solute-binding protein, family 5
D1816_07385	ENOG41081WG	50s ribosomal protein l31
D1816_07425	ENOG4105CKK	Glycosyl transferase, family 2
D1816_07435	ENOG4105BZ1	(ABC) transporter
D1816_07440	ENOG4105EMN	RNA polymerase sigma factor
D1816_07470	ENOG4108ETH	Formylglycinamide ribotide synthetase
D1816_07480	ENOG4108IQE	Amp-dependent synthetase and ligase
D1816_07485	ENOG4105FS7	Transcriptional regulator
D1816_07495	ENOG4105CHU	acetyl-coa acetyltransferase
D1816_07500	ENOG4105C1G	acyl-Coa dehydrogenase
D1816_07535	ENOG4108ZXC	Two component transcriptional regulator, luxr family
D1816_07545	ENOG4105C27	TonB-dependent Receptor Plug
D1816_07595	ENOG4107VAM	peptidase, m28
D1816_07600	ENOG4108SA1	esterase
D1816_07605	ENOG410829K	Lysine exporter protein (Lyse ygga)
D1816_07620	ENOG4107SMB	hydrolase Family 5
D1816_07630	ENOG4108HRK	Histidine kinase
D1816_07635	ENOG4108NEV	two component transcriptional regulator, LytTR family
D1816_07640	ENOG4105E2D	ec 3.2.1.52
D1816_07645	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
D1816_07655	ENOG4105C27	TonB-dependent Receptor Plug
D1816_07660	ENOG4105DY9	regulatoR
D1816_07665	ENOG4105CK7	Sodium proline symporter
D1816_07735	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
D1816_07795	ENOG4105CD3	dihydroorotase
D1816_07820	ENOG4105EUB	pirin domain protein
D1816_07825	ENOG4105BZU	Histidine kinase
D1816_07830	ENOG4105BZU	Histidine kinase
D1816_07865	ENOG4105E8R	UPF0173 metal-dependent hydrolase
D1816_07890	ENOG4105E5G	Alpha beta hydrolase fold
D1816_07910	ENOG4105K63	Thioredoxin
D1816_07920	ENOG4108Z40	Transcriptional regulator
D1816_07925	ENOG4108JSS	Haloalkane dehalogenase
D1816_07955	ENOG41066YJ	Beta-lactamase
D1816_07985	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
D1816_07995	ENOG4105K6V	RNA polymerase
D1816_08045	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D1816_08050	ENOG4105CEP	NADH dehydrogenase
D1816_08080	ENOG4108HRK	Histidine kinase
D1816_08100	ENOG4105DY9	regulatoR
D1816_08115	ENOG4105P8F	nudix hydrolase
D1816_08120	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
D1816_08150	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D1816_08180	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1816_08205	ENOG4105C5Q	Transcriptional regulator
D1816_08270	ENOG4105C3M	thioredoxin reductase
D1816_08275	ENOG4105EN6	Membrane
D1816_08325	ENOG4105D05	Receptor
D1816_08360	ENOG4105C0B	DNA polymerase III (alpha subunit)
D1816_08370	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
D1816_08390	ENOG4105DY9	regulatoR
D1816_08440	ENOG4105C4M	(Ubiquinol oxidase) subunit I
D1816_08460	ENOG4105BZU	Histidine kinase
D1816_08470	ENOG4107T9C	Alpha amylase catalytic region
D1816_08510	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D1816_08645	ENOG4108QBX	(LipO)protein
D1816_08650	ENOG4107TT5	NLP P60 protein
D1816_08690	ENOG4108MQB	beta-agarase
D1816_08705	ENOG4105DT9	hydrolase family 43
D1816_08730	ENOG4105D64	Mechanosensitive ion channel
D1816_08740	ENOG4105DY9	regulatoR
D1816_08745	ENOG4108HRK	Histidine kinase
D1816_08765	ENOG4105D8V	Glucose sorbosone dehydrogenase
D1816_08770	ENOG4107TJ9	Cytochrome
D1816_08780	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
D1816_08785	ENOG4105DBI	uridine monophosphokinase
D1816_08795	ENOG4105CMN	Methylmalonyl-coA mutase
D1816_08805	ENOG4105D5P	Methylmalonyl-coA mutase
D1816_08810	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
D1816_08815	ENOG4107QJE	Chromosome Partitioning Protein
D1816_08820	ENOG4105FA0	parb-like partition protein
D1816_08830	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
D1816_08835	ENOG4105C3F	Signal peptidase i
D1816_08870	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
D1816_08880	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
D1816_08890	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
D1816_08920	ENOG4105EMN	RNA polymerase sigma factor
D1816_08925	ENOG4108S3W	Anti-feci sigma factor, fecr
D1816_08935	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
D1816_08945	ENOG4105SFS	phosphoesterase RecJ domain protein
D1816_08955	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
D1816_08960	ENOG4105CIN	aminoacyl-histidine dipeptidase
D1816_08990	ENOG4105C5R	Aminotransferase
D1816_09005	ENOG4105CDU	Replicative dna helicase
D1816_09010	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
D1816_09025	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
D1816_09030	ENOG4108HHA	Transketolase
D1816_09035	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
D1816_09055	ENOG4105VEJ	Heat shock protein
D1816_09060	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
D1816_09065	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
D1816_09105	ENOG4107UWA	esterase
D1816_09115	ENOG4105CNT	hydrolase family 2
D1816_09120	ENOG41075H3	AraC family transcriptional regulator
D1816_09135	ENOG4106A3M	Cytochrome p-450
D1816_09140	ENOG4107RUZ	Sss sodium solute transporter superfamily
D1816_09145	ENOG4105C93	Xylose Isomerase
D1816_09150	ENOG4105W4W	Transcriptional regulator
D1816_09165	ENOG4105CNT	hydrolase family 2
D1816_09170	ENOG41061MV	Arylsulfatase
D1816_09180	ENOG4105E6M	Sulphatase-modifying factor protein
D1816_09185	ENOG4105C27	TonB-dependent Receptor Plug
D1816_09190	ENOG4105TT1	Ragb susd domain-containing protein
D1816_09230	ENOG4107SYN	Glycosyl hydrolases family 43
D1816_09235	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
D1816_09240	ENOG4105QNJ	serralysin (EC 3.4.24.40)
D1816_09250	ENOG41061MV	Arylsulfatase
D1816_09255	ENOG4105CBG	Sulfatase
D1816_09260	ENOG4105CNT	hydrolase family 2
D1816_09265	ENOG41061MV	Arylsulfatase
D1816_09275	ENOG4105CNT	hydrolase family 2
D1816_09280	ENOG4108K2F	hydrolase Family 5
D1816_09290	ENOG4108KBQ	ec 3.2.1.81
D1816_09315	ENOG4105CPQ	Dehydrogenase
D1816_09330	ENOG4105CTX	dehydratase
D1816_09335	ENOG4107QZW	Altronate oxidoreductase
D1816_09345	ENOG4105CHR	reductase
D1816_09350	ENOG4105EDR	glucose galactose transporter
D1816_09355	ENOG4105QJH	Domain of unknown function (DUF718)
D1816_09360	ENOG4105CBG	Sulfatase
D1816_09370	ENOG4105CNT	hydrolase family 2
D1816_09395	ENOG4106HBX	Transcriptional Regulator AraC Family
D1816_09425	ENOG4105CHR	reductase
D1816_09435	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
D1816_09445	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D1816_09510	ENOG4105DY9	regulatoR
D1816_09520	ENOG4105ENH	Sulfatase
D1816_09530	ENOG4105BZU	Histidine kinase
D1816_09535	ENOG4105CNT	hydrolase family 2
D1816_09575	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1816_09590	ENOG4108I0Z	Aconitate hydratase
D1816_09595	ENOG4107QIJ	Aconitate hydratase 2
D1816_09605	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D1816_09610	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
D1816_09620	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
D1816_09640	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D1816_09645	ENOG4106CKV	Pap2 superfamily protein
D1816_09710	ENOG41090A1	ferritin
D1816_09765	ENOG410829K	Lysine exporter protein (Lyse ygga)
D1816_09770	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
D1816_09775	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
D1816_09785	ENOG4105VIE	preprotein translocase, subunit YajC
D1816_09795	ENOG4107R6T	Involved in the transcription termination process (By similarity)
D1816_09800	ENOG4107RDP	Dehydrogenase
D1816_09805	ENOG4105BZ1	(ABC) transporter
D1816_09840	ENOG4108YYS	metal-dependent hydrolase (By similarity)
D1816_09850	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
D1816_09860	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D1816_09865	ENOG4105C2X	Arabinose 5-phosphate isomerase
D1816_09870	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
D1816_09880	ENOG4108IUZ	ABC transporter
D1816_09885	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
D1816_09890	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
D1816_09895	ENOG4105C5H	ABC transporter
D1816_09905	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
D1816_09910	ENOG4105C19	ABC transporter
D1816_09915	ENOG4107RJ1	sodium solute
D1816_09930	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
D1816_09940	ENOG4105WH1	Two component transcriptional regulator luxr family
D1816_09945	ENOG4108XG2	Histidine kinase
D1816_09960	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
D1816_09965	ENOG4105WH1	Two component transcriptional regulator luxr family
D1816_10010	ENOG4107XVH	Transcriptional regulator
D1816_10020	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
D1816_10025	ENOG410667J	hydrolase
D1816_10065	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1816_10095	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
D1816_10110	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D1816_10115	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D1816_10120	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
D1816_10125	ENOG4107VNI	ribosomal protein l10
D1816_10130	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
D1816_10135	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
D1816_10155	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
D1816_10180	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
D1816_10185	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D1816_10190	ENOG41083X6	30S ribosomal protein S21
D1816_10195	ENOG4105E5K	Alpha-amylase
D1816_10200	ENOG4105C1G	acyl-Coa dehydrogenase
D1816_10210	ENOG4105BZG	amino acid carrier protein
D1816_10215	ENOG4107SVH	Potassium channel protein
D1816_10250	ENOG4105EHZ	conserved protein UCP016719
D1816_10320	ENOG4105CAK	Cell division ATP-binding protein ftsE
D1816_10325	ENOG4108Z7R	Chaperone CsaA
D1816_10335	ENOG4105CI3	gtp-binding protein typa
D1816_10345	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
D1816_10355	ENOG4105C5Q	Transcriptional regulator
D1816_10360	ENOG4105CH6	catalase
D1816_10395	ENOG4105CT7	inner membrane cred family protein
D1816_10415	ENOG4106HBX	Transcriptional Regulator AraC Family
D1816_10425	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D1816_10445	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D1816_10455	ENOG4105CAQ	asparagine synthetase
D1816_10465	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
D1816_10470	ENOG4105KME	endoribonuclease L-psp
D1816_10475	ENOG4105D7A	ATP-binding protein
D1816_10485	ENOG4108Z2K	Cupin 2, conserved barrel domain protein
D1816_10495	ENOG4105FE9	pseudouridine synthase
D1816_10515	ENOG4105C26	Dehydrogenase
D1816_10520	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
D1816_10535	ENOG4105BZU	Histidine kinase
D1816_10535	ENOG4105BZU	Histidine kinase
D1816_10545	ENOG4105C3M	thioredoxin reductase
D1816_10570	ENOG4105CT4	transporter
D1816_10600	ENOG41063TF	transcriptional regulator (AraC
D1816_10650	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
D1816_10660	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
D1816_10665	ENOG4108CSZ	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
D1816_10690	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
D1816_10695	ENOG4105CSV	Glutaminase
D1816_10770	ENOG4108N9J	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
D1816_10785	ENOG4108K0D	peptidase, M48
D1816_10795	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
D1816_10825	ENOG4105CJ2	(LipO)protein
D1816_10850	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D1816_10860	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D1816_10865	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D1816_10870	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D1816_10885	ENOG4105NWN	ApaG protein
D1816_10900	ENOG4105C26	Dehydrogenase
D1816_10940	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
D1816_10950	ENOG4105CHM	Aminotransferase
D1816_10960	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
D1816_10965	ENOG4105C1A	potassium transporter peripheral membrane
D1816_10970	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
D1816_10990	ENOG4105D2N	Aldolase
D1816_10995	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
D1816_11005	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
D1816_11010	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
D1816_11040	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D1816_11060	ENOG4105ECQ	AraC Family Transcriptional Regulator
D1816_11065	ENOG4105DY8	decarboxylase
D1816_11175	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
D1816_11200	ENOG4105DJV	ribulose-phosphate 3-epimerase
D1816_11215	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
D1816_11225	ENOG4108MN8	Membrane
D1816_11245	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
D1816_11270	ENOG4105D9P	serine threonine protein kinase
D1816_11300	ENOG4105EUJ	GTP cyclohydrolase i
D1816_11315	ENOG4108HRK	Histidine kinase
D1816_11320	ENOG4105DY9	regulatoR
D1816_11325	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
D1816_11340	ENOG4105CUV	Homoserine Kinase
D1816_11350	ENOG4105K5X	acetyltransferase
D1816_11390	ENOG4105E1F	short-chain dehydrogenase reductase
D1816_11430	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
D1816_11450	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
D1816_11500	ENOG4105KTH	gatB Yqey
D1816_11505	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
D1816_11510	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
D1816_11520	ENOG4105DFU	Cell wall formation (By similarity)
D1816_11525	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
D1816_11530	ENOG4105CNI	cell division protein FtsW
D1816_11535	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
D1816_11540	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
D1816_11545	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
D1816_11550	ENOG4105CJN	penicillin-binding protein
D1816_11560	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
D1816_11565	ENOG4107YM1	mraZ protein
D1816_11575	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
D1816_11595	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
D1816_11605	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
D1816_11640	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
D1816_11650	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
D1816_11655	ENOG4107S18	3-phosphoshikimate 1-carboxyvinyltransferase
D1816_11685	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
D1816_11690	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
D1816_11700	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
D1816_11705	ENOG4105EVN	Prephenate dehydrogenase
D1816_11710	ENOG4105CHM	Aminotransferase
D1816_11715	ENOG4105CQC	Prephenate dehydratase
D1816_11720	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D1816_11730	ENOG4105EW9	transcriptional regulator AsnC family
D1816_11735	ENOG4105CS2	ec 3.2.1.21
D1816_11740	ENOG4105CJ1	ABC, transporter
D1816_11745	ENOG4108RQS	Two component transcriptional regulator (Winged helix family
D1816_11750	ENOG4105BZU	Histidine kinase
D1816_11770	ENOG4105SYT	Methylenetetrahydrofolate reductase
D1816_11780	ENOG4105C3R	Methionine synthase
D1816_11785	ENOG4105C3R	Methionine synthase
D1816_11805	ENOG4108ZIT	Ferredoxin, 2FE-2S
D1816_11815	ENOG4105CAY	ferredoxin--nadp reductase
D1816_11820	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
D1816_11830	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
D1816_11840	ENOG4105C11	sulfate adenylyltransferase), subunit 2
D1816_11860	ENOG4105C28	cystathionine
D1816_11865	ENOG4108UKZ	OsmC family
D1816_11870	ENOG4105CA0	peroxidase
D1816_11885	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
D1816_11940	ENOG4105ZMH	deoxynucleoside kinase
D1816_11970	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
D1816_11975	ENOG4105C0D	helicase
D1816_11980	ENOG4105CD3	dihydroorotase
D1816_12005	ENOG4107VIJ	nudix hydrolase
D1816_12015	ENOG4105CPT	Alpha beta hydrolase
D1816_12030	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
D1816_12040	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
D1816_12060	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
D1816_12070	ENOG4105BZU	Histidine kinase
D1816_12075	ENOG4105WH1	Two component transcriptional regulator luxr family
D1816_12085	ENOG41067HS	methyltransferase
D1816_12100	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
D1816_12105	ENOG4105D9N	nucleoside
D1816_12115	ENOG4105C10	Electron transfer flavoprotein
D1816_12120	ENOG4105BZJ	Electron transfer flavoprotein
D1816_12135	ENOG4105F0N	pyrophosphate phospho-hydrolase
D1816_12140	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
D1816_12245	ENOG4107VWA	Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation (By similarity)
D1816_12255	ENOG4105EMN	RNA polymerase sigma factor
D1816_12275	ENOG4105DVT	helicase
D1816_12295	ENOG4105DFA	alanine racemase domain protein
D1816_12305	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
D1816_12340	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
D1816_12345	ENOG4105CHR	reductase
D1816_12350	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
D1816_12360	ENOG4105FTV	AraC Family Transcriptional Regulator
D1816_12370	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
D1816_12445	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
D1816_12540	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
D1816_12550	ENOG4107V87	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase (By similarity)
D1816_12555	ENOG41086DT	Membrane protein of unknown function
D1816_12565	ENOG4105ISI	outer membrane protein, OMPP1 FadL TodX family
D1816_12570	ENOG4105EV9	Alpha Beta Hydrolase
D1816_12575	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
D1816_12585	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
D1816_12595	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
D1816_12615	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
D1816_12620	ENOG4105DY9	regulatoR
D1816_12625	ENOG4108HRK	Histidine kinase
D1816_12655	ENOG4108ZHR	arsR family transcriptional regulator
D1816_12660	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
D1816_12680	ENOG4105DJ4	phosphatidylserine decarboxylase
D1816_12705	ENOG4105C7Z	Conserved Protein
D1816_12725	ENOG41072GX	Peptidase M22 Glycoprotease
D1816_12740	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
D1816_12745	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D1816_12750	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D1816_12755	ENOG4105C19	ABC transporter
D1816_12765	ENOG4108SJC	Membrane
D1816_12770	ENOG4108KF3	Electron transport protein SCO1 SenC
D1816_12790	ENOG4105CCU	oxidase (Subunit III)
D1816_12795	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
D1816_12820	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
D1816_12830	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
D1816_12840	ENOG4105EC3	peptidase S51, dipeptidase E
D1816_12845	ENOG4105C6K	Malic enzyme
D1816_12870	ENOG4105FQP	Beta-lactamase
D1816_12895	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
D1816_12905	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
D1816_12920	ENOG4107XCH	Cyclase family
D1816_12930	ENOG4105DJB	Major Facilitator Superfamily
D1816_12935	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
D1816_12945	ENOG4105BZ9	Cytochrome C oxidase, subunit I
D1816_12950	ENOG4105Z4T	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
D1816_12975	ENOG4107SFQ	iron-sulfur binding
D1816_12990	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
D1816_12995	ENOG4105CHV	Transcription elongation factor NusA
D1816_13000	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
D1816_13020	ENOG4108ZJ4	polysaccharide deacetylase
D1816_13025	ENOG4105K63	Thioredoxin
D1816_13035	ENOG4105C2M	dna polymerase I
D1816_13065	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
D1816_13070	ENOG4108UJD	30S ribosomal protein S9
D1816_13075	ENOG4105CE9	30S ribosomal protein S2
D1816_13080	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
D1816_13085	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
D1816_13090	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
D1816_13105	ENOG4105C5S	asparaginyl-tRNA synthetase
D1816_13125	ENOG4107QWR	cellulase (EC 3.2.1.4)
D1816_13145	ENOG4105K8R	UPF0145 protein
D1816_13175	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
D1816_13215	ENOG4105BZU	Histidine kinase
D1816_13220	ENOG4105WH1	Two component transcriptional regulator luxr family
D1816_13225	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D1816_13275	ENOG4105HDK	L-asparaginase
D1816_13280	ENOG4105F8V	Hydrolase, tatD family
D1816_13335	ENOG4105DC1	bifunctional purine biosynthesis protein purh
D1816_13340	ENOG4105DFF	Rod shape-determining protein mreb
D1816_13355	ENOG4105CJN	penicillin-binding protein
D1816_13360	ENOG4105CNI	cell division protein FtsW
D1816_13375	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
D1816_13380	ENOG4105CN1	protease
D1816_13385	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
D1816_13395	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D1816_13400	ENOG4107TT5	NLP P60 protein
D1816_13405	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
D1816_13420	ENOG4105DUX	Transporter
D1816_13425	ENOG4105DUX	Transporter
D1816_13430	ENOG4105C5Z	peptidase
D1816_13465	ENOG4105FJR	Lmbe family
D1816_13485	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
D1816_13500	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
D1816_13515	ENOG41064MX	Tetr family transcriptional regulator
D1816_13520	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
D1816_13525	ENOG4105C7S	Dehydrogenase
D1816_13530	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
D1816_13555	ENOG4108IG5	Transcriptional regulator
D1816_13570	ENOG4105BZS	acriflavin resistance protein
D1816_13580	ENOG4105C27	TonB-dependent Receptor Plug
D1816_13585	ENOG4105C9M	aspartyl-trna synthetase
D1816_13610	ENOG4105VEQ	Cold shock protein
D1816_13630	ENOG4108Z6B	deaminase
D1816_13635	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
D1816_13660	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
D1816_13675	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
D1816_13690	ENOG4105CN1	protease
D1816_13705	ENOG4106855	Competence protein
D1816_13715	ENOG4107QHF	type ii secretion system protein e
D1816_13990	ENOG4105DJB	Major Facilitator Superfamily
D1816_13995	ENOG4105DRR	Transcriptional regulator, GntR family
D1816_14000	ENOG4108S2Y	peptide Chain Release factor
D1816_14010	ENOG4105E0Y	RtcB Protein
D1816_14040	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
D1816_14045	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
D1816_14050	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
D1816_14055	ENOG4105DTN	riboflavin biosynthesis protein ribF
D1816_14070	ENOG4105QNF	Outer membrane lipoprotein
D1816_14090	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
D1816_14105	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
D1816_14110	ENOG4105CJW	magnesium transporter
D1816_14115	ENOG4105E5P	Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation
D1816_14165	ENOG4108JQ1	Dehydrogenase
D1816_14175	ENOG4105WH1	Two component transcriptional regulator luxr family
D1816_14225	ENOG4108Z7F	N-acetyltransferase
D1816_14230	ENOG4108UXE	Protein tyrosine phosphatase
D1816_14240	ENOG4105D64	Mechanosensitive ion channel
D1816_14255	ENOG4105CFH	Aspartokinase
D1816_14265	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
D1816_14285	ENOG4105BZU	Histidine kinase
D1816_14315	ENOG4105C9B	Cysteine desulfurase
D1816_14330	ENOG4108JA2	transcriptioN-repair coupling factor
D1816_14370	ENOG4105CPC	Aldo Keto reductase
D1816_14375	ENOG41080R2	UPF0102 protein
D1816_14380	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
D1816_14395	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
D1816_14405	ENOG4105DGU	Histone deacetylase
D1816_14415	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D1816_14435	ENOG4105E33	succinate dehydrogenase
D1816_14450	ENOG4105CHM	Aminotransferase
D1816_14480	ENOG41080ZE	Adenylate cyclase
D1816_14505	ENOG4108JQB	penicillin-binding protein 1C
D1816_14520	ENOG4105DHF	Membrane
D1816_14530	ENOG4105DN3	alpha-2-macroglobulin domain protein
D1816_14550	ENOG4105D44	asparaginase
D1816_14580	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
D1816_14605	ENOG4108Y6J	UPF0403 protein
D1816_14610	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
D1816_14640	ENOG4105CE1	Ferrous iron transport protein b
D1816_14655	ENOG4108KF3	Electron transport protein SCO1 SenC
D1816_14660	ENOG4105DZP	Membrane-associated zinc metalloprotease
D1816_14670	ENOG4105VRS	hydrolase family 18
D1816_14680	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
D1816_14695	ENOG4107QJE	Chromosome Partitioning Protein
D1816_14835	ENOG4108V1T	peptidylprolyl cis-trans isomerase
D1816_14855	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D1816_14860	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D1816_14900	ENOG4107RUZ	Sss sodium solute transporter superfamily
D1816_14925	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
D1816_14940	ENOG4107R37	Glutamate dehydrogenase
D1816_14945	ENOG4105C28	cystathionine
D1816_14995	ENOG4105DVW	rieske (2Fe-2S)
D1816_15025	ENOG4105FFC	UPF0187 protein
D1816_15030	ENOG4105DNZ	Alpha Beta Hydrolase
D1816_15045	ENOG4105CB2	alcohol dehydrogenase
D1816_15070	ENOG4105C0F	tryptophanase EC 4.1.99.1
D1816_15085	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
D1816_15095	ENOG4105E0C	molybdate abc transporter
D1816_15100	ENOG4108IJ6	ABC transporter
D1816_15145	ENOG4108NEV	two component transcriptional regulator, LytTR family
D1816_15150	ENOG4108HRK	Histidine kinase
D1816_15155	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
D1816_15180	ENOG4105D52	delta-aminolevulinic acid dehydratase
D1816_15185	ENOG4105CJ1	ABC, transporter
D1816_15225	ENOG4107VE4	peptidase S8 and S53, subtilisin, kexin, sedolisin
D1816_15235	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D1816_15240	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D1816_15275	ENOG4107RBB	ABC transporter, permease
D1816_15290	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D1816_15295	ENOG4107RBB	ABC transporter, permease
D1816_15305	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D1816_15340	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
D1816_15345	ENOG4105EXN	Sulfate transport protein CysZ
D1816_15355	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
D1816_15370	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
D1816_15375	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
D1816_15385	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
D1816_15425	ENOG41082IR	Excinuclease ABC C subunit domain protein
D1816_15445	ENOG4105DSJ	YicC domain protein
D1816_15450	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
D1816_15455	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
D1816_15500	ENOG4105E39	Enoyl-CoA hydratase
D1816_15515	ENOG4108IIH	CoA-transferase subunit B
D1816_15525	ENOG4105D3R	alkyl hydroperoxide reductase
D1816_15530	ENOG4107QP7	CoA-transferase subunit A
D1816_15535	ENOG4108JQC	penicillin-binding protein 1A
D1816_15540	ENOG410647Z	gliding motility-associated lipoprotein GldH
D1816_15545	ENOG4105MA4	psp1 domain protein
D1816_15550	ENOG4105C72	UPF0176 protein
D1816_15560	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
D1816_15575	ENOG4105EMN	RNA polymerase sigma factor
D1816_15585	ENOG4108WS4	fmn reductase
D1816_15600	ENOG4105C31	Tryptophanyl-tRNA synthetase
D1816_15635	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
D1816_15690	ENOG4105CHH	sulfate transporter
D1816_15725	ENOG4107Z6X	Transcriptional regulator
D1816_15755	ENOG4107QVM	von Willebrand factor, type A
D1816_15775	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D1816_15780	ENOG4105EMU	Dehydrogenase
D1816_15840	ENOG4105C26	Dehydrogenase
D1816_15845	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
D1816_15855	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
D1816_15865	ENOG4105KHC	sulfurtransferase
D1816_15870	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
D1816_15885	ENOG4108IG5	Transcriptional regulator
D1816_15950	ENOG4105NAU	thioesterase Superfamily protein
D1816_15975	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
D1816_16005	ENOG4105DY9	regulatoR
D1816_16010	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
D1816_16015	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
D1816_16020	ENOG4107Z4P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D1816_16025	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
D1816_16030	ENOG410842R	atp synthase
D1816_16035	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
D1816_16070	ENOG4108EGH	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
D1816_16095	ENOG4107QNG	Phosphoribosylglycinamide synthetase
D1816_16130	ENOG4105PF3	O-Antigen polymerase
D1816_16135	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
D1816_16140	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
D1816_16155	ENOG4105D5U	fad dependent oxidoreductase
D1816_16170	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
D1816_16180	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
D1816_16215	ENOG4108REZ	Imidazole glycerol phosphate synthase
D1816_16220	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
D1816_16235	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
D1816_16245	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
D1816_16260	ENOG4105DG6	mannose-6-phosphate isomerase
D1816_16280	ENOG41061JJ	Peptidase family M23
D1816_16285	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
D1816_16335	ENOG4105E9H	Lytic Murein transglycosylase
D1816_16340	ENOG4105BZA	Phosphoglycerate kinase
D1816_16350	ENOG4107QRG	dna polymerase iii
D1816_16405	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
D1816_16410	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
D1816_16425	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
D1816_16430	ENOG4105EPW	hflc protein
D1816_16435	ENOG4108ZIS	hydrolase, family 16
D1816_16445	ENOG4105CX6	glutaminyL-tRNA synthetase
D1816_16450	ENOG4105KRF	dihydroneopterin aldolase
D1816_16470	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
D1816_16480	ENOG4108YZG	isomerase
D1816_16485	ENOG4105PGM	cation diffusion facilitator family transporter
D1816_16490	ENOG4107YB6	acetyltransferase, (GNAT) family
D1816_16515	ENOG4108QT4	peptidase S8 and S53, subtilisin, kexin, sedolisin
D1816_16585	ENOG4105C8F	Beta-lactamase domain protein
D1816_16600	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
D1816_16605	ENOG4105CN1	protease
D1816_16630	ENOG4108YQE	rare lipoprotein a
D1816_16645	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
D1816_16670	ENOG4105VG1	fes assembly suf system protein
D1816_16675	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
D1816_16730	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
D1816_16735	ENOG4105CA0	peroxidase
D1816_16760	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
D1816_16780	ENOG4105CA0	peroxidase
D1816_16820	ENOG4107T6F	Xaa-Pro aminopeptidase
D1816_16835	ENOG4108ZGC	gaf domain protein
D1816_16855	ENOG4108YBA	Histidine kinase
D1816_16860	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
D1816_16865	ENOG4105CA9	Pyruvate kinase
D1816_16875	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
D1816_16880	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D1816_16885	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
D1816_16890	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
D1816_16895	ENOG4108B1Q	Ribonuclease
D1816_16935	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
D1816_16940	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
D1816_16945	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
D1816_16955	ENOG4105C5N	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
D1816_16985	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
D1816_16990	ENOG4105BZU	Histidine kinase
D1816_17025	ENOG41075H3	AraC family transcriptional regulator
D1816_17050	ENOG4107QI1	Mate efflux family protein
D1816_17060	ENOG41066YJ	Beta-lactamase
D1816_17065	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
D1816_17070	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
D1816_17080	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D1816_17100	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
D1816_17105	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
D1816_17110	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
D1816_17115	ENOG4107T8J	thymidine kinase
D1816_17170	ENOG4105BZU	Histidine kinase
D1816_17185	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
D1816_17195	ENOG4105CPT	Alpha beta hydrolase
D1816_17215	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
D1816_17225	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
D1816_17230	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
D1816_17235	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
D1816_17240	ENOG4105WXV	50S ribosomal protein L32
D1816_17250	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
D1816_17255	ENOG4108R6K	riboflavin synthase, subunit alpha
D1816_17290	ENOG4107VAM	peptidase, m28
D1816_17295	ENOG4105D7N	magnesium and cobalt transport protein CorA
D1816_17305	ENOG4105DUX	Transporter
D1816_17330	ENOG4108ZVT	methylmalonyl-coA epimerase
D1816_17340	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
D1816_17355	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
D1816_17360	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
D1816_17450	ENOG4106F1P	AAA ATPase, central domain protein
D1816_17455	ENOG4108HCJ	Hydrolase
D1816_17460	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
D1816_17470	ENOG4108KPZ	tonB-dependent Receptor
D1816_17480	ENOG4107QP8	phosphohexose isomerase
D1816_17500	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
D1816_17505	ENOG4105F1J	Homogentisate 1,2-dioxygenase
D1816_17510	ENOG4105D78	K07001 NTE family protein
D1816_17515	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
D1816_17525	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
D1816_17535	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
D1816_17540	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
D1816_17545	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
D1816_17565	ENOG4108AEY	RNA polymerase sigma factor
D1816_17570	ENOG4108UHE	carbonic anhydrase
D1816_17575	ENOG4108UHE	carbonic anhydrase
D1816_17590	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
D1816_17615	ENOG4105MJ2	Competence protein
D1816_17625	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
D1816_17640	ENOG4105CGK	Exodeoxyribonuclease III
D1816_17645	ENOG4105ER2	Ompa motb domain protein
D1816_17685	ENOG4105CPC	Aldo Keto reductase
D1816_17720	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
D1816_17735	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
D1816_17740	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
D1816_17745	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
D1816_17755	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
D1816_17790	ENOG4105C09	Bile acid
D1816_17795	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
D1816_17810	ENOG4105CJ1	ABC, transporter
D1816_17815	ENOG4108HRK	Histidine kinase
D1816_17820	ENOG4105DY9	regulatoR
D1816_17835	ENOG4105C0H	protease
D1816_17840	ENOG4105VMP	Transcriptional regulator
D1816_17850	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D1816_17855	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
D1816_17865	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
D1816_17880	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D1816_17885	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
D1816_17905	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
D1816_18000	ENOG4108JJA	ABC, transporter
D1816_18050	ENOG4105C03	ribonuclease
D1816_18055	ENOG4105K70	DNA-binding protein
D1816_18065	ENOG4108UUM	single-stranded DNA-binding protein
D1816_18070	ENOG4105C37	(CBS) domain
D1816_18080	ENOG4108594	Permease of the drug metabolite transporter
D1816_18090	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
D1816_18095	ENOG4105K46	50S ribosomal protein l27
D1816_18115	ENOG4105DA5	(ABC) transporter
D1816_18120	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
D1816_18150	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
D1816_18160	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1816_18165	ENOG4105BZU	Histidine kinase
D1816_18180	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
D1816_18190	ENOG4105DWF	phosphomethylpyrimidine kinase
D1816_18195	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
D1816_18200	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
D1816_18205	ENOG4105D41	biosynthesis protein thiH
D1816_18215	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
D1816_18235	ENOG4105BZU	Histidine kinase
D1816_18240	ENOG4107XWI	flavin reductase domain protein, FMN-binding
D1816_18250	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
D1816_18255	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
D1816_18260	ENOG4105C27	TonB-dependent Receptor Plug
D1816_18275	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
D1816_18280	ENOG4107RE3	peptidase, S41
D1816_18295	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
D1816_18300	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
D1816_18315	ENOG4107QZC	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
D1816_18320	ENOG4107RJ9	Cell division protein FtsX
D1816_18325	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
D1816_18330	ENOG4105C8T	Leucyl-tRNA synthetase
D1816_18340	ENOG4105W3H	MtN3 and saliva related transmembrane protein
D1816_18355	ENOG4108VVK	transcriptional Regulator, AsnC
D1816_18375	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
D1816_18390	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
D1816_18395	ENOG4105CD3	dihydroorotase
D1816_18410	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
D1816_18455	ENOG4105C27	TonB-dependent Receptor Plug
D1816_18470	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D1816_18475	ENOG4105BZU	Histidine kinase
D1816_18480	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
D1816_18485	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
D1816_18525	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D1816_18590	ENOG4108Q35	Adenylate
D1816_18605	ENOG4107YZX	Universal stress protein
D1816_18670	ENOG4105K63	Thioredoxin
D1816_18700	ENOG4105D4P	Coproporphyrinogen iii oxidase
D1816_18730	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
D1816_18745	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
D1816_18750	ENOG4105C59	p-type ATPase
D1816_18765	ENOG4107YZX	Universal stress protein
D1816_18775	ENOG4107YZX	Universal stress protein
D1816_18815	ENOG4105C5I	Dehydrogenase
D1816_18835	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
D1816_18865	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
D1816_18875	ENOG4105D06	uba thif-type nad fad binding protein
D1816_18885	ENOG41080H2	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
D1816_18890	ENOG4105F4R	Transcriptional regulator mode
D1816_18895	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
D1816_18945	ENOG4107FQX	Alpha-acetolactate decarboxylase
D1816_18955	ENOG4105CYW	agmatinase
D1816_19000	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
D1816_19005	ENOG4105CT4	transporter
D1816_19010	ENOG4105HY2	Glycosidase related protein
D1816_19015	ENOG4105DFY	n-acylglucosamine 2-epimerase
D1816_19020	ENOG4105C27	TonB-dependent Receptor Plug
D1816_19045	ENOG41075H3	AraC family transcriptional regulator
D1816_19070	ENOG4105CJ1	ABC, transporter
D1816_19125	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
D1816_19195	ENOG4108IJF	Heavy metal efflux pump, CzcA
D1816_19220	ENOG410681U	heavy metal transport detoxification protein
D1816_19265	ENOG4105EP1	Efflux transporter rnd family, mfp subunit
D1816_19295	ENOG4105JD4	ATPase yjob
D1816_19325	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
D1816_19380	ENOG4105CVR	type I restriction-modification system
D1816_19405	ENOG4105W5Q	DNA repair protein (RadC
D1816_19435	ENOG4105FA0	parb-like partition protein
D1816_19485	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
D1816_19490	ENOG4105CTU	Proline racemase
D1816_19495	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
D1816_19530	ENOG4105CSA	Coproporphyrinogen iii oxidase
D1816_19535	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
D1816_19560	ENOG4105CYP	glycoside hydrolase, family
D1816_19575	ENOG4105CYP	glycoside hydrolase, family
D1816_19580	ENOG4106R7G	Glycoside hydrolase family 5
D1816_19595	ENOG4107G87	m6 family metalloprotease domain protein
D1816_19680	ENOG4105C0B	DNA polymerase III (alpha subunit)
D1816_19710	ENOG4105K5M	30s ribosomal protein S16
D1816_19715	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
D1816_19720	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
D1816_19730	ENOG4105C1G	acyl-Coa dehydrogenase
D1816_19760	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
D1816_19765	ENOG4105CBX	hi0933 family
D1816_19780	ENOG4107Z3H	Transcriptional regulator, TetR family
D1816_19785	ENOG4105KAV	tspo and mbr like protein
D1816_19815	ENOG4105FE9	pseudouridine synthase
D1816_19825	ENOG4105CND	Glycosyl transferase, family 2
D1816_19845	ENOG4108IFG	nitrite reductase, (NAD(P)H)
D1816_19885	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
D1816_19895	ENOG4105E7U	AraC family transcriptional regulator
D1816_19920	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D1816_19935	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
D1816_19945	ENOG4105C72	UPF0176 protein
D1816_19955	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D1816_19970	ENOG4105VNH	ABC transporter solute-binding protein
D1816_19990	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
D1816_19995	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
D1816_20005	ENOG4105ETE	Transcriptional regulator (LacI family
D1816_20015	ENOG4105CG3	alpha amylase, catalytic region
D1816_20020	ENOG4105C27	TonB-dependent Receptor Plug
D1816_20055	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
D1816_20060	ENOG4108WIQ	phosphoesterase PA-phosphatase related protein
D1816_20085	ENOG4105CHU	acetyl-coa acetyltransferase
D1816_20125	ENOG4105CNT	hydrolase family 2
D1816_20135	ENOG4105DZ2	Transcriptional regulator
D1816_20145	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
D1816_20150	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
D1816_20175	ENOG4108IXY	short-chain dehydrogenase reductase
D1816_20180	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
D1816_20235	ENOG4105C1G	acyl-Coa dehydrogenase
D1816_20270	ENOG4105EQD	regulatoR
D1816_20275	ENOG4105EMU	Dehydrogenase
D1816_20285	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
D1816_20310	ENOG4105C37	(CBS) domain
D1816_20315	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
D1816_20320	ENOG4105CMR	udp-glucose 4-epimerase
D1816_20325	ENOG4105D4U	had-superfamily hydrolase, subfamily iia
D1816_20330	ENOG4107RUZ	Sss sodium solute transporter superfamily
D1816_20350	ENOG4105C27	TonB-dependent Receptor Plug
D1816_20355	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
D1816_20365	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
D1816_20370	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
D1816_20390	ENOG4107QP3	malate synthase g
D1816_20400	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
D1816_20405	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
D1816_20425	ENOG4107SM7	Transcriptional regulator
D1816_20430	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
D1816_20440	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
D1816_20445	ENOG41088SP	formiminoglutamate hydrolase
D1816_20450	ENOG4105E6M	Sulphatase-modifying factor protein
D1816_20480	ENOG4105C5H	ABC transporter
D1816_20545	ENOG4105BZU	Histidine kinase
D1816_20595	ENOG410874W	AraC family transcriptional regulator
D1816_20685	ENOG4105EMU	Dehydrogenase
D1816_20700	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D1816_20710	ENOG4108RCM	Nitroreductase
D1816_20715	ENOG410874W	AraC family transcriptional regulator
D1816_20720	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
D1816_20745	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D1816_20750	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
D1816_20770	ENOG4105D05	Receptor
D1816_20785	ENOG4107RET	Isocitrate lyase
D1816_20790	ENOG4105CKK	Glycosyl transferase, family 2
D1816_20820	ENOG4105C27	TonB-dependent Receptor Plug
D1816_20855	ENOG4105DY8	decarboxylase
D1816_20860	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
D1816_20870	ENOG4105DUU	IucA IucC family protein
D1816_20875	ENOG4105DUU	IucA IucC family protein
D1816_20935	ENOG4105DSQ	Nitric oxide reductase
D1816_20965	ENOG410630P	Transcriptional regulator
D1816_20970	ENOG4105CKK	Glycosyl transferase, family 2
D1816_21015	ENOG4107QJZ	Glycosyl transferase, family 2
D1816_21025	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
D1816_21035	ENOG4108NEV	two component transcriptional regulator, LytTR family
D1816_21045	ENOG4105BZU	Histidine kinase
D1816_21055	ENOG4105BZU	Histidine kinase
D1816_21090	ENOG4107QIM	DNA ligase
D1816_21095	ENOG4107QRT	dEAD DEAH box helicase
D1816_21115	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
D1816_21120	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
D1816_21150	ENOG4105C27	TonB-dependent Receptor Plug
D1816_21175	ENOG4105DY9	regulatoR
D1816_21200	ENOG4105BZG	amino acid carrier protein
D1816_21210	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
D1816_21225	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
D1816_21245	ENOG4105C4X	radical SAM domain protein
D1816_21300	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
D1816_21310	ENOG4105MIR	Phenylalanine 4-monooxygenase
D1816_21330	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
D1816_21335	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
D1816_21340	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
D1816_21345	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
D1816_21350	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
D1816_21360	ENOG4108UKI	Enoyl-CoA hydratase
D1816_21365	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
D1816_21380	ENOG4105CHU	acetyl-coa acetyltransferase
D1816_21385	ENOG4105DXM	phenylacetic acid degradation protein
D1816_21400	ENOG4105C7S	Dehydrogenase
D1816_21405	ENOG4105CM2	brancheD-chain amino acid aminotransferase
D1816_21410	ENOG4105CPP	Dehydrogenase, E1 component
D1816_21435	ENOG4105CNT	hydrolase family 2
D1816_21445	ENOG4107RUZ	Sss sodium solute transporter superfamily
D1816_21450	ENOG4105C09	Bile acid
D1816_21460	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
D1816_21465	ENOG4105EEQ	Na H antiporter
D1816_21470	ENOG4105C7K	acetolactate synthase
D1816_21485	ENOG4105CBC	glutamate synthase
D1816_21495	ENOG4108UUM	single-stranded DNA-binding protein
D1816_21535	ENOG410904A	RNA polymerase
D1816_21540	ENOG4105JAB	phenazine biosynthesis protein, phzf family
D1816_21565	ENOG4105K6H	D-cysteine desulfhydrase
D1816_21570	ENOG41068JE	domain protein
D1816_21575	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
D1816_21620	ENOG4108Z12	YiaAB two helix domain-containing protein
D1816_21655	ENOG4105CRK	lysyL-tRNA synthetase
D1816_21675	ENOG41061ZR	Transcriptional regulator
D1816_21680	ENOG4105VPI	YqaE family transport protein
D1816_21690	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
D1816_21705	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
D1816_21750	ENOG4105C1G	acyl-Coa dehydrogenase
D1816_21760	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
D1816_21770	ENOG4109015	Biopolymer transport protein exbD tolR
D1816_21795	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
D1816_21800	ENOG4105E6M	Sulphatase-modifying factor protein
D1816_21810	ENOG4105KG3	cytidine deaminase
D1816_21830	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
D1816_21855	ENOG4105GPY	SprT protein
D1816_21860	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
D1816_21895	ENOG4107ZT5	Thiol disulfide interchange protein
D1816_21900	ENOG4107R8N	Glycosyl transferase, family 2
D1816_21910	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
D1816_21920	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D1816_21980	ENOG4105DGW	oligopeptidase A
D1816_21985	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
D1816_21990	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
D1816_21995	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
D1816_22000	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D1816_22015	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
D1816_22040	ENOG4107S85	alpha-2-macroglobulin domain protein
D1816_22045	ENOG4105DFU	Cell wall formation (By similarity)
D1816_22065	ENOG4105W5Q	DNA repair protein (RadC
D1816_22095	ENOG4105D1H	recombination factor protein RarA
D1816_22105	ENOG4105C2N	RNA methyltransferase TrmH family group 3
D1816_22115	ENOG4105C27	TonB-dependent Receptor Plug
D1816_22125	ENOG4105C27	TonB-dependent Receptor Plug
D1816_22145	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
D1816_22150	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
D1816_22155	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
D1816_22160	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
D1816_22165	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
D1816_22170	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
D1816_22175	ENOG41082S5	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
D1816_22180	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D1816_22185	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
D1816_22190	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
D1816_22195	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
D1816_22200	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
D1816_22205	ENOG4105WNB	50s ribosomal protein l29
D1816_22210	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
D1816_22215	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
D1816_22220	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
D1816_22225	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D1816_22230	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
D1816_22235	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
D1816_22240	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
D1816_22245	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
D1816_22250	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
D1816_22255	ENOG41084HK	50S ribosomal protein L30
D1816_22260	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
D1816_22265	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
D1816_22270	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
D1816_22275	ENOG410864M	50S ribosomal protein L36
D1816_22280	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D1816_22285	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
D1816_22290	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
D1816_22295	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D1816_22300	ENOG4108ZT0	50S ribosomal protein l17
D1816_22305	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
D1816_22310	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
D1816_22330	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
D1816_22340	ENOG4105CGD	Nad-dependent epimerase dehydratase
D1816_22345	ENOG4105C75	arginyL-tRNA synthetase
D1816_22360	ENOG4108S3W	Anti-feci sigma factor, fecr
D1816_22390	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
D1816_22400	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
D1816_22405	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
D1816_22420	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
D1816_22425	ENOG4105BZ1	(ABC) transporter
D1816_22435	ENOG4105C8B	TIGR00159 family
D1816_22440	ENOG4105EEI	dihydropteroate synthase
D1816_22455	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
D1816_22460	ENOG4105CP7	Triose-phosphate isomerase
D1816_22465	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
D1816_22490	ENOG4105BZ1	(ABC) transporter
D1816_22505	ENOG4105CMG	Carbohydrate kinase
D1816_22510	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
D1816_22520	ENOG4105BZU	Histidine kinase
D1816_22525	ENOG4105M3Z	response regulator
D1816_22535	ENOG4108IJF	Heavy metal efflux pump, CzcA
D1816_22570	ENOG4108HRK	Histidine kinase
D1816_22575	ENOG4105DY9	regulatoR
D1816_22595	ENOG4105CRE	cytochrome C
D1816_22600	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
D1816_22635	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
D1816_22655	ENOG4108HRK	Histidine kinase
D1816_22660	ENOG4105DY9	regulatoR
D1816_22665	ENOG4108ZX5	transcriptional regulator
D1816_22685	ENOG4105C0H	protease
D1816_22695	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
D1816_22710	ENOG4107SFQ	iron-sulfur binding
D1816_22720	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
D1816_22725	ENOG4107QZB	decarboxylase
D1816_22730	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
D1816_22755	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
D1816_22805	ENOG4105CPN	adenine deaminase
D1816_22815	ENOG4106A4F	Removes the N-terminal methionine from nascent proteins (By similarity)
D1816_22835	ENOG4105CTK	cobaltochelatase, cobn subunit
D1816_22840	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
D1816_22845	ENOG4105EET	magnesium chelatase
D1816_22865	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
D1816_22875	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
D1816_22880	ENOG4107XSI	cobalt-precorrin-6y C15-methyltransferase
D1816_22885	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
D1816_22890	ENOG4105E4R	Precorrin-3B C17-methyltransferase
D1816_22900	ENOG4108WBT	adenosyltransferase
D1816_22910	ENOG4105WAB	arsR family transcriptional regulator
D1816_22915	ENOG4105ECP	epimerase
D1816_22930	ENOG4105CUZ	uba thif-type nad fad binding protein
D1816_22960	ENOG4108JJA	ABC, transporter
D1816_23000	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D1816_23045	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
D1816_23075	ENOG4107R5B	glutamine synthetase
D1816_23105	ENOG4105P8Q	Curli production assembly transport component CsgG
D1816_23115	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
D1816_23120	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
D1816_23125	ENOG4105BZU	Histidine kinase
D1816_23130	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
D1816_23140	ENOG4107QWR	cellulase (EC 3.2.1.4)
D1816_23150	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
D1816_23155	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
D1816_23160	ENOG4105C8N	cysteinyl-tRNA synthetase
D1816_23165	ENOG4105EUJ	GTP cyclohydrolase i
D1816_23185	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
D1816_23200	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
D1816_23220	ENOG4105EGD	dinuclear metal center protein, YbgI family
D1816_23225	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
D1816_23230	ENOG4105BZU	Histidine kinase
D1816_23235	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D1816_23240	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
D1816_23260	ENOG4107R0I	Cell wall formation (By similarity)
D1816_23265	ENOG4105CHM	Aminotransferase
D1816_23270	ENOG4105DZP	Membrane-associated zinc metalloprotease
D1816_23280	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
D1816_23290	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
D1816_23295	ENOG4105KNE	Phosphatidate cytidylyltransferase
D1816_23305	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
D1816_23310	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
D1816_23325	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
D1816_23330	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
D1816_23350	ENOG4105CHH	sulfate transporter
D1816_23375	ENOG4108KBQ	ec 3.2.1.81
D1816_23380	ENOG4108KBQ	ec 3.2.1.81
D1816_23385	ENOG4108KBQ	ec 3.2.1.81
D1816_23410	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
D1816_23415	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
D1816_23420	ENOG4105CPF	Cell wall formation (By similarity)
D1816_23430	ENOG4105C34	Pseudouridine synthase
D1816_23435	ENOG4105VEQ	Cold shock protein
D1816_23450	ENOG4108KBQ	ec 3.2.1.81
D1816_23460	ENOG4105D1Q	UPF0246 protein
D1816_23470	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D1816_23475	ENOG4105CH5	extracellular solute-binding protein, family 7
D1816_23485	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
D1816_23510	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
D1816_23520	ENOG4106MZZ	glycerophosphoryl diester phosphodiesterase
D1816_23525	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
D1816_23530	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
D1816_23535	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
D1816_23545	ENOG4105DK0	Indole-3-glycerol phosphate synthase
D1816_23550	ENOG4108I0Q	anthranilate phosphoribosyltransferase
D1816_23555	ENOG4105DDQ	anthranilate synthase
D1816_23560	ENOG4105CRQ	synthase (Component I)
D1816_23575	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1816_23585	ENOG41085GJ	domain protein
D1816_23590	ENOG41082J7	Rhodanese domain protein
D1816_23595	ENOG4108UHU	Aldolase
D1816_23610	ENOG4105QRC	ig domain protein group 2 domain protein
D1816_23620	ENOG4105TT1	Ragb susd domain-containing protein
D1816_23625	ENOG4105C27	TonB-dependent Receptor Plug
D1816_23640	ENOG4105ETE	Transcriptional regulator (LacI family
D1816_23650	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
D1816_23655	ENOG4105DIA	mandelate racemase muconate lactonizing
D1816_23660	ENOG4105C26	Dehydrogenase
D1816_23665	ENOG4105CHR	reductase
D1816_23680	ENOG4105CNT	hydrolase family 2
D1816_23715	ENOG4105CHR	reductase
D1816_23815	ENOG4105WH1	Two component transcriptional regulator luxr family
D1816_23835	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
D1816_23840	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
D1816_23865	ENOG4105D5P	Methylmalonyl-coA mutase
D1816_23875	ENOG4105BZG	amino acid carrier protein
D1816_23880	ENOG4105CQM	Urea amidohydrolase subunit alpha
D1816_23900	ENOG4105ECQ	AraC Family Transcriptional Regulator
D1816_23905	ENOG4106K7D	Major facilitator family transporter
D1816_23920	ENOG4108YZA	Nitrogen regulatory protein pii
D1816_23925	ENOG41083GQ	Protein CrcB homolog
D1816_23950	ENOG4105BZU	Histidine kinase
D1816_23975	ENOG4105CM2	brancheD-chain amino acid aminotransferase
D1816_23985	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
D1816_23990	ENOG4105ECP	epimerase
D1816_24000	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D1816_24005	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
D1816_24010	ENOG4108IUX	(ABC) transporter
D1816_24015	ENOG4105RHA	ABC transporter, permease
D1816_24020	ENOG4105EGS	Mechanosensitive ion channel
D1816_24040	ENOG4105CSR	polyphosphate kinase 2
D1816_24065	ENOG4107QI1	Mate efflux family protein
D1816_24085	ENOG4108JQC	penicillin-binding protein 1A
D1816_24100	ENOG4105DJT	lAO AO transport system ATPase
D1816_24140	ENOG4105EMN	RNA polymerase sigma factor
D1816_24150	ENOG4105H3G	oxidoreductase
D1816_24170	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
D1816_24180	ENOG4108WBT	adenosyltransferase
D1816_24185	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
D1816_24225	ENOG4107RBD	ABC, transporter
D1816_24230	ENOG4107RPQ	ABC transporter
D1816_24235	ENOG4105DIK	(ABC) transporter
D1816_24240	ENOG4105DSE	periplasmic solute binding protein
D1816_24250	ENOG4105D05	Receptor
D1816_24255	ENOG4107RPQ	ABC transporter
D1816_24260	ENOG4108IRC	dna polymerase iii
D1816_24265	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
D1816_24275	ENOG4105CEV	competence damage-inducible protein
D1816_24295	ENOG4105KDC	50s ribosomal protein l28
D1816_24300	ENOG41083ND	50S ribosomal protein L33
D1816_24310	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
D1816_24350	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
D1816_24355	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D1816_24365	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
D1816_24380	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
D1816_24415	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
D1816_24420	ENOG4107S1E	Beta-lactamase
D1816_24425	ENOG41075H3	AraC family transcriptional regulator
D1816_24445	ENOG4105CPQ	Dehydrogenase
D1816_24455	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1816_24475	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
D1816_24520	ENOG4105DGW	oligopeptidase A
D1816_24530	ENOG41074B2	UPF0747 protein
D1816_24575	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
D1816_24590	ENOG4105VRT	cytoplasmic protein
D1816_24600	ENOG4105CI2	imidazolone-5-propionate hydrolase
D1816_24605	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
D1816_24615	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
D1816_24630	ENOG4107SET	aldo keto reductase
D1816_24660	ENOG4105VN1	Heat shock protein
D1816_24680	ENOG4105C08	Histidine kinase
D1816_24695	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
D1816_24725	ENOG4105CJ1	ABC, transporter
D1816_24760	ENOG4107SF2	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
D1816_24765	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
D1816_24770	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
D1816_24785	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
D1816_24805	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
D1816_24810	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
D1816_24815	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
D1816_24825	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
D1816_24830	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
D1816_24850	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
D1816_24855	ENOG4105EA8	2-Nitropropane dioxygenase
D1816_24860	ENOG4105DXN	mazG family
D1816_24865	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
D1816_24880	ENOG4105E2X	shikimate dehydrogenase
D1816_24900	ENOG4105C8Y	Acetylornithine aminotransferase
D1816_24915	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
D1816_24920	ENOG4105I3K	Ferric uptake regulator, Fur family
D1816_24925	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
D1816_24930	ENOG4105D0M	Protease HtpX homolog
D1816_24935	ENOG4108RWN	rrna methyltransferase
D1816_24940	ENOG4105BZU	Histidine kinase
D1816_24950	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
D1816_24955	ENOG4105VJV	50s ribosomal protein L35
D1816_24960	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
D1816_24965	ENOG4105C22	threonyL-tRNA synthetase
D1816_24995	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1816_25015	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D1816_25050	ENOG4105EMN	RNA polymerase sigma factor
D1816_25055	ENOG4105E9K	Isocitrate dehydrogenase
D1816_25060	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
D1816_25065	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
D1816_25080	ENOG4105C0H	protease
D1816_25085	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
D1816_25095	ENOG4105HHA	aminodeoxychorismate lyase
D1816_25115	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
D1816_25125	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
D1816_25140	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
D1816_25150	ENOG4108MJ3	acetyltransferase
D1816_25155	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
D1816_25160	ENOG4108URH	decarboxylase
D1816_25165	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
D1816_25200	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
D1816_25230	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
D1816_25235	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
D1816_25240	ENOG4105K64	Glycosyl transferase, family 2
D1816_25250	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
D1816_25265	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
D1816_25270	ENOG4105EYW	Ion transport protein
D1816_25280	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
D1816_25285	ENOG4105DFA	alanine racemase domain protein
D1816_25300	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
D1816_25315	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
D1816_25320	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
D1816_25355	ENOG4108IG5	Transcriptional regulator
D1816_25365	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D1816_25385	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
D1816_25410	ENOG4107QN2	dihydrolipoyl dehydrogenase
D1816_25415	ENOG4105CPC	Aldo Keto reductase
D1816_25420	ENOG4108NEV	two component transcriptional regulator, LytTR family
D1816_25425	ENOG4105C2F	Histidine kinase
D1816_25435	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1816_25465	ENOG4105BZ1	(ABC) transporter
D1816_25470	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
D1816_25480	ENOG4105S2T	inner membrane protein YbcI