locus-tag	class	description
D1818_00065	ENOG4105C7H	Helicase, RecD TraA family
D1818_00075	ENOG4107RJC	Iron-containing alcohol dehydrogenase
D1818_00090	ENOG4105CDY	transcriptional regulatory protein
D1818_00095	ENOG4105KZX	Pterin carbinolamine dehydratase
D1818_00105	ENOG4108Z03	MAF-like protein
D1818_00145	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
D1818_00150	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
D1818_00155	ENOG4107U9T	Pfam:Ribonuclease_BN
D1818_00180	ENOG4105C25	Primosomal protein n'
D1818_00190	ENOG4108NEV	two component transcriptional regulator, LytTR family
D1818_00195	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
D1818_00200	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
D1818_00205	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
D1818_00220	ENOG4107RBB	ABC transporter, permease
D1818_00225	ENOG4105CUT	histidyl-tRNA synthetase
D1818_00275	ENOG4105F0I	Aminotransferase
D1818_00285	ENOG4105K70	DNA-binding protein
D1818_00290	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
D1818_00295	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D1818_00315	ENOG4105XRQ	Xanthine dehydrogenase accessory factor
D1818_00320	ENOG410838B	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
D1818_00335	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
D1818_00340	ENOG4105C1J	atp-dependent rna helicase
D1818_00345	ENOG4105DUX	Transporter
D1818_00350	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
D1818_00365	ENOG4105CSU	acyl-Coa dehydrogenase
D1818_00370	ENOG4105CHR	reductase
D1818_00395	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
D1818_00405	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
D1818_00410	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
D1818_00415	ENOG4105CHR	reductase
D1818_00440	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
D1818_00450	ENOG4105BZU	Histidine kinase
D1818_00460	ENOG41088SP	formiminoglutamate hydrolase
D1818_00465	ENOG4105CGP	Urocanate hydratase
D1818_00475	ENOG4105C84	Histidine ammonia-lyase
D1818_00480	ENOG4107RSM	transcriptional regulator
D1818_00495	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
D1818_00500	ENOG4105CHR	reductase
D1818_00510	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
D1818_00520	ENOG4105EE0	oxidoreductase
D1818_00530	ENOG4105CHR	reductase
D1818_00545	ENOG4105BZU	Histidine kinase
D1818_00555	ENOG4107QKZ	Ompa motb domain protein
D1818_00560	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
D1818_00565	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
D1818_00575	ENOG4105CIH	Imidazole acetol-phosphate transaminase
D1818_00585	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
D1818_00600	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
D1818_00610	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
D1818_00615	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
D1818_00630	ENOG4105CDV	Ompa motb domain protein
D1818_00635	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
D1818_00640	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
D1818_00645	ENOG4105CXT	aspartate transcarbamylase
D1818_00660	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
D1818_00670	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
D1818_00685	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
D1818_00750	ENOG4105CPK	Glycosyl transferase (Group 1
D1818_00775	ENOG4105CQB	FAD linked oxidase domain protein
D1818_00790	ENOG4105FQP	Beta-lactamase
D1818_00800	ENOG4108Q35	Adenylate
D1818_00810	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
D1818_00815	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
D1818_00820	ENOG4105C6Z	Gluconate
D1818_00855	ENOG4108RCM	Nitroreductase
D1818_00860	ENOG4105KVH	Transcriptional regulator
D1818_00875	ENOG4105F7P	transcriptional regulator AsnC family
D1818_00905	ENOG4105N14	lysine exporter protein LysE YggA
D1818_00945	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D1818_00950	ENOG4105CIH	Imidazole acetol-phosphate transaminase
D1818_00955	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
D1818_00960	ENOG4105CK2	sodium dicarboxylate symporter
D1818_00965	ENOG4105DY8	decarboxylase
D1818_00970	ENOG4105DY9	regulatoR
D1818_00975	ENOG4108HRK	Histidine kinase
D1818_01010	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
D1818_01020	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
D1818_01080	ENOG4105VC4	domain protein
D1818_01095	ENOG4105VC4	domain protein
D1818_01115	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
D1818_01125	ENOG4107XZC	Restriction modification system DNA (Specificity
D1818_01135	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
D1818_01190	ENOG4108Q35	Adenylate
D1818_01195	ENOG4108Q35	Adenylate
D1818_01235	ENOG4108NEV	two component transcriptional regulator, LytTR family
D1818_01265	ENOG4105C26	Dehydrogenase
D1818_01270	ENOG4105EMU	Dehydrogenase
D1818_01350	ENOG4105D98	threonine synthase
D1818_01355	ENOG4108176	endoribonuclease L-psp
D1818_01360	ENOG4107RDY	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
D1818_01365	ENOG4105CFH	Aspartokinase
D1818_01370	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
D1818_01390	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D1818_01435	ENOG4107QN2	dihydrolipoyl dehydrogenase
D1818_01445	ENOG4105E0X	reductase
D1818_01450	ENOG4105E0X	reductase
D1818_01470	ENOG4105JAB	phenazine biosynthesis protein, phzf family
D1818_01480	ENOG4105WAB	arsR family transcriptional regulator
D1818_01495	ENOG4105CAT	Cytidine monophosphate kinase
D1818_01505	ENOG4108I7Y	domain protein
D1818_01515	ENOG4108RPX	mosc domain containing protein
D1818_01520	ENOG4105H3G	oxidoreductase
D1818_01530	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D1818_01555	ENOG4108IUM	Glycogen debranching enzyme
D1818_01560	ENOG4105C6T	cysteine synthase
D1818_01565	ENOG4105D7W	serine acetyltransferase
D1818_01570	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D1818_01590	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
D1818_01595	ENOG4105YA8	Transcriptional regulator
D1818_01630	ENOG4107SN7	NLP P60 protein
D1818_01635	ENOG4105CHU	acetyl-coa acetyltransferase
D1818_01640	ENOG4105CTJ	Metal Dependent Phosphohydrolase
D1818_01655	ENOG4105CUY	Mechanosensitive ion channel
D1818_01680	ENOG4107T9C	Alpha amylase catalytic region
D1818_01690	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
D1818_01695	ENOG4107W2A	UPF0173 metal-dependent hydrolase
D1818_01700	ENOG4107TCW	O-succinylbenzoate synthase
D1818_01705	ENOG4107FCW	Abortive infection protein
D1818_01760	ENOG4105CP2	von willebrand factor, type a
D1818_01780	ENOG4107QX3	carboxylase
D1818_01795	ENOG4105C5H	ABC transporter
D1818_01830	ENOG4105VEQ	Cold shock protein
D1818_01845	ENOG4105CHH	sulfate transporter
D1818_01900	ENOG4105K5B	UPF0225 protein
D1818_01915	ENOG4105C4X	radical SAM domain protein
D1818_01925	ENOG4105EUB	pirin domain protein
D1818_01935	ENOG4105D29	Helix-turn-helix type 11 domain protein
D1818_01950	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
D1818_01955	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
D1818_01960	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
D1818_01985	ENOG4105UYK	outer membrane protein a
D1818_02015	ENOG41065KQ	synthase
D1818_02025	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
D1818_02030	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D1818_02035	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
D1818_02055	ENOG4105C2C	drug resistance transporter, Bcr CflA
D1818_02080	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
D1818_02120	ENOG4108C33	Resolvase
D1818_02200	ENOG4108KF3	Electron transport protein SCO1 SenC
D1818_02235	ENOG4105E39	Enoyl-CoA hydratase
D1818_02270	ENOG4105CKI	cobalamin synthesis protein
D1818_02275	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
D1818_02315	ENOG4108NEV	two component transcriptional regulator, LytTR family
D1818_02325	ENOG4105C2F	Histidine kinase
D1818_02330	ENOG4105DY9	regulatoR
D1818_02350	ENOG4105DZ2	Transcriptional regulator
D1818_02380	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
D1818_02410	ENOG4105VEQ	Cold shock protein
D1818_02435	ENOG4105BZU	Histidine kinase
D1818_02440	ENOG4108I6A	alcohol dehydrogenase
D1818_02450	ENOG4105HDD	phospholipase
D1818_02465	ENOG4105C27	TonB-dependent Receptor Plug
D1818_02475	ENOG4105DY9	regulatoR
D1818_02480	ENOG4108HRK	Histidine kinase
D1818_02490	ENOG4105DA5	(ABC) transporter
D1818_02515	ENOG4105CNG	UPF0061 protein
D1818_02600	ENOG4105C2F	Histidine kinase
D1818_02605	ENOG4108NEV	two component transcriptional regulator, LytTR family
D1818_02640	ENOG4105C26	Dehydrogenase
D1818_02655	ENOG4105EBA	Specifically methylates the adenine in position 1618 of 23S rRNA (By similarity)
D1818_02660	ENOG4108JA2	transcriptioN-repair coupling factor
D1818_02665	ENOG4108V1T	peptidylprolyl cis-trans isomerase
D1818_02715	ENOG4105EMN	RNA polymerase sigma factor
D1818_02725	ENOG4105BZU	Histidine kinase
D1818_02765	ENOG4105DR4	Methyltransferase
D1818_02770	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
D1818_02775	ENOG4108KPJ	rna polymerase sigma factor
D1818_02815	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
D1818_02820	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
D1818_02845	ENOG4105D7W	serine acetyltransferase
D1818_02850	ENOG4105D3Q	Sugar transferase
D1818_02870	ENOG4105D3Q	Sugar transferase
D1818_02910	ENOG4108KMV	Glycosyl transferase (Group 1
D1818_02930	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
D1818_02965	ENOG4107QQG	Dehydrogenase
D1818_02970	ENOG4108IAJ	Nad-dependent epimerase dehydratase
D1818_02980	ENOG4105CPP	Dehydrogenase, E1 component
D1818_03000	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
D1818_03005	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
D1818_03030	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
D1818_03035	ENOG4105C98	muts2 protein
D1818_03070	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
D1818_03080	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D1818_03085	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
D1818_03090	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D1818_03095	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D1818_03100	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D1818_03105	ENOG4105DCI	Phosphohydrolase
D1818_03110	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1818_03115	ENOG4105K8N	protein family UPF0079, ATPase
D1818_03130	ENOG4105DCF	alanine dehydrogenase
D1818_03145	ENOG4105XDF	Protein of unknown function (DUF1272)
D1818_03155	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
D1818_03160	ENOG4105C27	TonB-dependent Receptor Plug
D1818_03180	ENOG4105CYW	agmatinase
D1818_03210	ENOG4105D49	3-dehydroquinate synthase
D1818_03230	ENOG4105C8P	)-transporter
D1818_03240	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
D1818_03245	ENOG4108URH	decarboxylase
D1818_03265	ENOG4105CPP	Dehydrogenase, E1 component
D1818_03290	ENOG4105QNR	S1 RNA binding domain protein
D1818_03300	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
D1818_03305	ENOG4105E4F	Isochorismate synthase
D1818_03310	ENOG4105KA0	thioesterase Superfamily protein
D1818_03355	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
D1818_03365	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D1818_03385	ENOG4105CN1	protease
D1818_03410	ENOG4105KVH	Transcriptional regulator
D1818_03415	ENOG4107S9F	NmrA family
D1818_03435	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
D1818_03480	ENOG4105EMN	RNA polymerase sigma factor
D1818_03485	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
D1818_03490	ENOG4108VVK	transcriptional Regulator, AsnC
D1818_03510	ENOG4105EE5	Membrane protein terC
D1818_03515	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
D1818_03525	ENOG4105DF5	DNA topoisomerase IV, subunit A
D1818_03530	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
D1818_03540	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
D1818_03555	ENOG4105EWK	phytoene
D1818_03560	ENOG4105CSR	polyphosphate kinase 2
D1818_03565	ENOG4105CSR	polyphosphate kinase 2
D1818_03585	ENOG4105BZU	Histidine kinase
D1818_03595	ENOG4105C3G	gtp-binding protein
D1818_03620	ENOG4107RNH	Outer membrane receptor FepA
D1818_03640	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
D1818_03650	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
D1818_03655	ENOG4108JQ1	Dehydrogenase
D1818_03680	ENOG4105EUJ	GTP cyclohydrolase i
D1818_03685	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
D1818_03695	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D1818_03710	ENOG4105CA0	peroxidase
D1818_03715	ENOG4105BZU	Histidine kinase
D1818_03720	ENOG4105DZ0	fad dependent oxidoreductase
D1818_03730	ENOG4108NA0	Uncharacterized conserved protein (COG2071)
D1818_03745	ENOG4105C1J	atp-dependent rna helicase
D1818_03760	ENOG4105CD3	dihydroorotase
D1818_03800	ENOG4105D8V	Glucose sorbosone dehydrogenase
D1818_03810	ENOG4105UEI	Transcriptional Regulator AraC Family
D1818_03815	ENOG4105CJQ	hydrolase, family 31
D1818_03865	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1818_03870	ENOG4105CSM	endonuclease III
D1818_03880	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
D1818_03940	ENOG4107YCY	Transcriptional regulator
D1818_03945	ENOG4105C27	TonB-dependent Receptor Plug
D1818_03965	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D1818_03975	ENOG4105CUG	Oligopeptidase b
D1818_03980	ENOG41080WS	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
D1818_03985	ENOG4105UYK	outer membrane protein a
D1818_03990	ENOG4105KWI	UPF0339 protein
D1818_04010	ENOG4105K89	arsenate reductase
D1818_04030	ENOG4105C9Q	fumarate hydratase class II
D1818_04065	ENOG4105C28	cystathionine
D1818_04070	ENOG4105EW9	transcriptional regulator AsnC family
D1818_04115	ENOG4108IUK	alpha amylase, catalytic
D1818_04120	ENOG4108HRK	Histidine kinase
D1818_04125	ENOG4108NEV	two component transcriptional regulator, LytTR family
D1818_04140	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
D1818_04145	ENOG4105C1J	atp-dependent rna helicase
D1818_04150	ENOG4105S2T	inner membrane protein YbcI
D1818_04155	ENOG4107YH7	Beta-lactamase (EC 3.5.2.6)
D1818_04160	ENOG4105BZ1	(ABC) transporter
D1818_04175	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
D1818_04190	ENOG4105C2F	Histidine kinase
D1818_04195	ENOG4108NEV	two component transcriptional regulator, LytTR family
D1818_04200	ENOG4105CPC	Aldo Keto reductase
D1818_04205	ENOG4107QN2	dihydrolipoyl dehydrogenase
D1818_04215	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
D1818_04240	ENOG4108IXY	short-chain dehydrogenase reductase
D1818_04245	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1818_04265	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
D1818_04290	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D1818_04300	ENOG4108K8S	endonuclease I
D1818_04305	ENOG4108IG5	Transcriptional regulator
D1818_04315	ENOG4107QWR	cellulase (EC 3.2.1.4)
D1818_04345	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
D1818_04355	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
D1818_04360	ENOG4105CK5	oxidoreductase
D1818_04370	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
D1818_04375	ENOG4108K5P	(LipO)protein
D1818_04385	ENOG4105DFA	alanine racemase domain protein
D1818_04390	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
D1818_04400	ENOG4105EYW	Ion transport protein
D1818_04405	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
D1818_04435	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
D1818_04440	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
D1818_04470	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
D1818_04500	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
D1818_04510	ENOG4108MJ3	acetyltransferase
D1818_04520	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
D1818_04535	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
D1818_04550	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
D1818_04570	ENOG4105HHA	aminodeoxychorismate lyase
D1818_04580	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
D1818_04585	ENOG4105C0H	protease
D1818_04600	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
D1818_04605	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
D1818_04610	ENOG4105E9K	Isocitrate dehydrogenase
D1818_04620	ENOG4105EMN	RNA polymerase sigma factor
D1818_04655	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
D1818_04680	ENOG4105CNA	YD repeat protein
D1818_04750	ENOG4105BZU	Histidine kinase
D1818_04780	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
D1818_04785	ENOG4105C0B	DNA polymerase III (alpha subunit)
D1818_04815	ENOG4105C22	threonyL-tRNA synthetase
D1818_04820	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
D1818_04825	ENOG4105VJV	50s ribosomal protein L35
D1818_04830	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
D1818_04850	ENOG4105D0M	Protease HtpX homolog
D1818_04855	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
D1818_04860	ENOG4105I3K	Ferric uptake regulator, Fur family
D1818_04865	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
D1818_04885	ENOG4105E0K	tonB-dependent siderophore receptor
D1818_04920	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
D1818_04940	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
D1818_04945	ENOG4105C27	TonB-dependent Receptor Plug
D1818_04970	ENOG4105CBG	Sulfatase
D1818_05005	ENOG41061MV	Arylsulfatase
D1818_05015	ENOG41061MV	Arylsulfatase
D1818_05030	ENOG4105CNT	hydrolase family 2
D1818_05045	ENOG4105CNT	hydrolase family 2
D1818_05080	ENOG4105CNT	hydrolase family 2
D1818_05085	ENOG4105ENH	Sulfatase
D1818_05100	ENOG4105CHR	reductase
D1818_05105	ENOG4105CPQ	Dehydrogenase
D1818_05125	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
D1818_05135	ENOG4107YRA	Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system) (By similarity)
D1818_05150	ENOG4108RZ2	Glycoside hydrolase family 16
D1818_05155	ENOG4108KBQ	ec 3.2.1.81
D1818_05180	ENOG4105CPQ	Dehydrogenase
D1818_05190	ENOG4105CTX	dehydratase
D1818_05200	ENOG4107QZW	Altronate oxidoreductase
D1818_05210	ENOG4105CHR	reductase
D1818_05215	ENOG4105EDR	glucose galactose transporter
D1818_05220	ENOG4105QJH	Domain of unknown function (DUF718)
D1818_05235	ENOG4105C93	Xylose Isomerase
D1818_05240	ENOG4107RUZ	Sss sodium solute transporter superfamily
D1818_05250	ENOG4107QPD	alcohol dehydrogenase
D1818_05260	ENOG4107Z7P	Ferredoxin
D1818_05265	ENOG4106A3M	Cytochrome p-450
D1818_05285	ENOG4105E6M	Sulphatase-modifying factor protein
D1818_05290	ENOG4105C7Z	Conserved Protein
D1818_05305	ENOG4105C4M	(Ubiquinol oxidase) subunit I
D1818_05310	ENOG4105BZU	Histidine kinase
D1818_05370	ENOG4107T9C	Alpha amylase catalytic region
D1818_05385	ENOG4107G87	m6 family metalloprotease domain protein
D1818_05400	ENOG4105CBC	glutamate synthase
D1818_05445	ENOG4105DY9	regulatoR
D1818_05450	ENOG4108JA5	May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs (By similarity)
D1818_05490	ENOG4105NI8	Cytosine-specific methyltransferase
D1818_05535	ENOG4105DVF	Cytosine-specific methyltransferase
D1818_05650	ENOG4105KNA	-acetyltransferase
D1818_05680	ENOG4108AEY	RNA polymerase sigma factor
D1818_05740	ENOG4105C4W	S-formylglutathione hydrolase
D1818_05750	ENOG4108HRK	Histidine kinase
D1818_05755	ENOG4108NEV	two component transcriptional regulator, LytTR family
D1818_05770	ENOG4108YZA	Nitrogen regulatory protein pii
D1818_05790	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
D1818_05865	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1818_05880	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D1818_05885	ENOG4107RBB	ABC transporter, permease
D1818_05895	ENOG4107RBB	ABC transporter, permease
D1818_05900	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D1818_05920	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D1818_05930	ENOG4105C19	ABC transporter
D1818_05935	ENOG4105DFG	type I secretion outer membrane protein
D1818_05945	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
D1818_06050	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
D1818_06085	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D1818_06100	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
D1818_06120	ENOG4108RG0	uracil-dna glycosylase
D1818_06140	ENOG4105BZU	Histidine kinase
D1818_06145	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D1818_06150	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
D1818_06155	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
D1818_06195	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
D1818_06200	ENOG4107QX3	carboxylase
D1818_06230	ENOG4105EAA	nucleoside
D1818_06255	ENOG4105D7K	pfkb domain protein
D1818_06260	ENOG4105CH7	arginosuccinase
D1818_06270	ENOG4107T6X	nag kinase
D1818_06275	ENOG4107REN	Carbamoyltransferase
D1818_06280	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
D1818_06290	ENOG4105C8Y	Acetylornithine aminotransferase
D1818_06295	ENOG4105II7	pyrroline-5-carboxylate reductase
D1818_06300	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
D1818_06305	ENOG4105CDH	Citrulline--aspartate ligase
D1818_06320	ENOG4107YCY	Transcriptional regulator
D1818_06325	ENOG4105C27	TonB-dependent Receptor Plug
D1818_06345	ENOG4105EY3	heparinase II III family protein
D1818_06350	ENOG4105M5J	Cupin 2, conserved barrel domain protein
D1818_06355	ENOG4105DPW	Major facilitator superfamily MFS_1
D1818_06450	ENOG4108JJA	ABC, transporter
D1818_06470	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
D1818_06480	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
D1818_06485	ENOG4105VG0	50S ribosomal protein l34
D1818_06520	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
D1818_06525	ENOG4105DEF	Extracellular solute-binding protein, family 5
D1818_06540	ENOG41081WG	50s ribosomal protein l31
D1818_06565	ENOG4105CKK	Glycosyl transferase, family 2
D1818_06575	ENOG4105BZ1	(ABC) transporter
D1818_06580	ENOG4105EMN	RNA polymerase sigma factor
D1818_06620	ENOG4108IQE	Amp-dependent synthetase and ligase
D1818_06625	ENOG4105FS7	Transcriptional regulator
D1818_06640	ENOG4105CHU	acetyl-coa acetyltransferase
D1818_06645	ENOG4105C1G	acyl-Coa dehydrogenase
D1818_06670	ENOG4105C27	TonB-dependent Receptor Plug
D1818_06690	ENOG4105BZP	glycoside hydrolase 15-related
D1818_06695	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
D1818_06790	ENOG4108SA1	esterase
D1818_06820	ENOG4105C5H	ABC transporter
D1818_06880	ENOG4105EUB	pirin domain protein
D1818_06885	ENOG4105BZU	Histidine kinase
D1818_06890	ENOG4105BZU	Histidine kinase
D1818_07145	ENOG4105CHH	sulfate transporter
D1818_07200	ENOG4105K6V	RNA polymerase
D1818_07260	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D1818_07265	ENOG4105CEP	NADH dehydrogenase
D1818_07290	ENOG4108HRK	Histidine kinase
D1818_07315	ENOG4105DY9	regulatoR
D1818_07340	ENOG4105P8F	nudix hydrolase
D1818_07345	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
D1818_07375	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D1818_07395	ENOG4105C5Q	Transcriptional regulator
D1818_07450	ENOG4105C3M	thioredoxin reductase
D1818_07475	ENOG4105EN6	Membrane
D1818_07495	ENOG4105RKW	reductase (By
D1818_07540	ENOG4105CND	Glycosyl transferase, family 2
D1818_07565	ENOG4105EA8	2-Nitropropane dioxygenase
D1818_07575	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
D1818_07600	ENOG4105C8Y	Acetylornithine aminotransferase
D1818_07620	ENOG4105E2X	shikimate dehydrogenase
D1818_07635	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
D1818_07650	ENOG4105C27	TonB-dependent Receptor Plug
D1818_07660	ENOG4107VQW	regulatoR
D1818_07665	ENOG4105DXN	mazG family
D1818_07675	ENOG4106WTF	Glycosyl transferase, family 2
D1818_07680	ENOG4105EA8	2-Nitropropane dioxygenase
D1818_07690	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
D1818_07705	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
D1818_07710	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
D1818_07725	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
D1818_07735	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
D1818_07740	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
D1818_07765	ENOG4107QRS	glycosyltransferase group 2 family protein
D1818_07790	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
D1818_07795	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
D1818_07835	ENOG4105CJ1	ABC, transporter
D1818_07860	ENOG4105EKD	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism (By similarity)
D1818_07865	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
D1818_07885	ENOG4105CKU	formyltetrahydrofolate synthetase
D1818_07910	ENOG4105DY9	regulatoR
D1818_07915	ENOG4105CMR	udp-glucose 4-epimerase
D1818_07940	ENOG4105VN1	Heat shock protein
D1818_08005	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
D1818_08010	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
D1818_08015	ENOG4105D64	Mechanosensitive ion channel
D1818_08020	ENOG4105VIE	preprotein translocase, subunit YajC
D1818_08030	ENOG4107R6T	Involved in the transcription termination process (By similarity)
D1818_08035	ENOG4107RDP	Dehydrogenase
D1818_08040	ENOG4105BZ1	(ABC) transporter
D1818_08080	ENOG4108YYS	metal-dependent hydrolase (By similarity)
D1818_08090	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
D1818_08130	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D1818_08135	ENOG4105C2X	Arabinose 5-phosphate isomerase
D1818_08140	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
D1818_08150	ENOG4108IUZ	ABC transporter
D1818_08155	ENOG4105PNM	synthesis protein
D1818_08170	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
D1818_08180	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
D1818_08185	ENOG4105C5H	ABC transporter
D1818_08195	ENOG4105C19	ABC transporter
D1818_08215	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
D1818_08235	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
D1818_08240	ENOG4105WH1	Two component transcriptional regulator luxr family
D1818_08315	ENOG4107XVH	Transcriptional regulator
D1818_08325	ENOG4108EUD	Lysophospholipase
D1818_08330	ENOG410667J	hydrolase
D1818_08365	ENOG4105DG6	mannose-6-phosphate isomerase
D1818_08370	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1818_08385	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
D1818_08400	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
D1818_08415	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D1818_08420	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D1818_08425	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
D1818_08430	ENOG4107VNI	ribosomal protein l10
D1818_08435	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
D1818_08440	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
D1818_08460	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
D1818_08490	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D1818_08495	ENOG41083X6	30S ribosomal protein S21
D1818_08500	ENOG4105E5K	Alpha-amylase
D1818_08505	ENOG4105E5P	Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation
D1818_08510	ENOG4105C1G	acyl-Coa dehydrogenase
D1818_08520	ENOG4105BZG	amino acid carrier protein
D1818_08525	ENOG4107SVH	Potassium channel protein
D1818_08540	ENOG4108K01	transcriptional regulator
D1818_08550	ENOG4105D60	lipoprotein releasing system transmembrane protein
D1818_08555	ENOG4105EHZ	conserved protein UCP016719
D1818_08560	ENOG4105BZU	Histidine kinase
D1818_08565	ENOG4105WH1	Two component transcriptional regulator luxr family
D1818_08620	ENOG4105EFZ	amidohydrolase
D1818_08645	ENOG4105C34	Pseudouridine synthase
D1818_08650	ENOG4107S1E	Beta-lactamase
D1818_08655	ENOG4105E7U	AraC family transcriptional regulator
D1818_08670	ENOG4105DR5	peptidase
D1818_08690	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
D1818_08695	ENOG4105CAK	Cell division ATP-binding protein ftsE
D1818_08725	ENOG4105CG5	Glycosyl transferase (Group 1
D1818_08750	ENOG4105CI3	gtp-binding protein typa
D1818_08755	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
D1818_08770	ENOG4105C27	TonB-dependent Receptor Plug
D1818_08810	ENOG4105CT7	inner membrane cred family protein
D1818_08840	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D1818_08850	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D1818_08865	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D1818_08875	ENOG4105CAQ	asparagine synthetase
D1818_08885	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
D1818_08890	ENOG4105KME	endoribonuclease L-psp
D1818_08895	ENOG4105D7A	ATP-binding protein
D1818_08905	ENOG4108Z2K	Cupin 2, conserved barrel domain protein
D1818_08915	ENOG4105FE9	pseudouridine synthase
D1818_08930	ENOG4105C26	Dehydrogenase
D1818_08935	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
D1818_08945	ENOG4105BZU	Histidine kinase
D1818_08945	ENOG4105BZU	Histidine kinase
D1818_08955	ENOG4105C3M	thioredoxin reductase
D1818_08995	ENOG410874W	AraC family transcriptional regulator
D1818_09000	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
D1818_09045	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
D1818_09050	ENOG4108CSZ	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
D1818_09075	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
D1818_09080	ENOG4105CSV	Glutaminase
D1818_09100	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
D1818_09105	ENOG4105CKK	Glycosyl transferase, family 2
D1818_09110	ENOG4108YM7	Gcn5-related n-acetyltransferase
D1818_09115	ENOG4107R5Z	Oxidoreductase domain protein
D1818_09120	ENOG4105J5G	Transferase hexapeptide repeat containing protein
D1818_09165	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
D1818_09180	ENOG4105ERG	peptidase m48, ste24p
D1818_09190	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
D1818_09235	ENOG4108HRK	Histidine kinase
D1818_09240	ENOG4105DY9	regulatoR
D1818_09245	ENOG4105CJ2	(LipO)protein
D1818_09265	ENOG4105WH1	Two component transcriptional regulator luxr family
D1818_09290	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D1818_09295	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D1818_09300	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D1818_09305	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D1818_09310	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
D1818_09320	ENOG41065HY	1,4-beta-cellobiosidase
D1818_09330	ENOG4105NWN	ApaG protein
D1818_09345	ENOG4105C26	Dehydrogenase
D1818_09375	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
D1818_09385	ENOG4105CHM	Aminotransferase
D1818_09395	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
D1818_09400	ENOG4105C1A	potassium transporter peripheral membrane
D1818_09405	ENOG4107XM9	(LipO)protein
D1818_09410	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
D1818_09420	ENOG4105C2N	RNA methyltransferase TrmH family group 3
D1818_09430	ENOG4105D2N	Aldolase
D1818_09435	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
D1818_09450	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
D1818_09455	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
D1818_09510	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D1818_09530	ENOG4105DJV	ribulose-phosphate 3-epimerase
D1818_09535	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
D1818_09565	ENOG4105EPI	acetyltransferase, (GNAT) family
D1818_09575	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
D1818_09580	ENOG4108U51	Universal stress protein
D1818_09585	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
D1818_09590	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
D1818_09595	ENOG4105K63	Thioredoxin
D1818_09620	ENOG4105BZU	Histidine kinase
D1818_09625	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D1818_09635	ENOG4105D4P	Coproporphyrinogen iii oxidase
D1818_09670	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
D1818_09685	ENOG4105DX1	Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation (By similarity)
D1818_09725	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
D1818_09730	ENOG4105C59	p-type ATPase
D1818_09750	ENOG4107YZX	Universal stress protein
D1818_09830	ENOG4107TPS	domain protein
D1818_09850	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
D1818_09915	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D1818_09930	ENOG4108V06	Glutathione peroxidase
D1818_09945	ENOG4108JYZ	YitT family
D1818_09970	ENOG4105E5N	succinylglutamate desuccinylase aspartoacylase
D1818_10010	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
D1818_10040	ENOG4105CKI	cobalamin synthesis protein
D1818_10045	ENOG4105CGH	5'-nucleotidase
D1818_10050	ENOG4105CGH	5'-nucleotidase
D1818_10065	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D1818_10075	ENOG4105EUJ	GTP cyclohydrolase i
D1818_10135	ENOG4105KTH	gatB Yqey
D1818_10140	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
D1818_10145	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
D1818_10155	ENOG4105DFU	Cell wall formation (By similarity)
D1818_10160	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
D1818_10165	ENOG4105CNI	cell division protein FtsW
D1818_10170	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
D1818_10175	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
D1818_10180	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
D1818_10185	ENOG4105CJN	penicillin-binding protein
D1818_10195	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
D1818_10200	ENOG4107YM1	mraZ protein
D1818_10210	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
D1818_10230	ENOG4107RW9	nh(3)-dependent nad( ) synthetase
D1818_10240	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
D1818_10275	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
D1818_10285	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
D1818_10290	ENOG4107S18	3-phosphoshikimate 1-carboxyvinyltransferase
D1818_10315	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
D1818_10320	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
D1818_10325	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
D1818_10330	ENOG4105EVN	Prephenate dehydrogenase
D1818_10335	ENOG4105CHM	Aminotransferase
D1818_10340	ENOG4105CQC	Prephenate dehydratase
D1818_10345	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D1818_10350	ENOG4105EXW	epimerase dehydratase
D1818_10355	ENOG4105EW9	transcriptional regulator AsnC family
D1818_10360	ENOG4108IUW	ABC transporter
D1818_10385	ENOG4105TT1	Ragb susd domain-containing protein
D1818_10390	ENOG4105SYT	Methylenetetrahydrofolate reductase
D1818_10395	ENOG4105C3R	Methionine synthase
D1818_10400	ENOG4105C3R	Methionine synthase
D1818_10410	ENOG4105CAY	ferredoxin--nadp reductase
D1818_10415	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
D1818_10420	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
D1818_10425	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
D1818_10435	ENOG4105C11	sulfate adenylyltransferase), subunit 2
D1818_10465	ENOG4105C28	cystathionine
D1818_10470	ENOG4108UKZ	OsmC family
D1818_10485	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
D1818_10550	ENOG4105ZMH	deoxynucleoside kinase
D1818_10575	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
D1818_10585	ENOG4105C0D	helicase
D1818_10595	ENOG4105CPN	adenine deaminase
D1818_10605	ENOG4108SA1	esterase
D1818_10615	ENOG4105CPT	Alpha beta hydrolase
D1818_10620	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
D1818_10630	ENOG4108HRK	Histidine kinase
D1818_10640	ENOG4107QWR	cellulase (EC 3.2.1.4)
D1818_10645	ENOG4105FGM	Fructosamine kinase
D1818_10650	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
D1818_10675	ENOG41067HS	methyltransferase
D1818_10690	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
D1818_10695	ENOG4105D9N	nucleoside
D1818_10705	ENOG4105C10	Electron transfer flavoprotein
D1818_10710	ENOG4105BZJ	Electron transfer flavoprotein
D1818_10715	ENOG4105CPP	Dehydrogenase, E1 component
D1818_10725	ENOG4105F0N	pyrophosphate phospho-hydrolase
D1818_10730	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
D1818_10815	ENOG4105DY9	regulatoR
D1818_10830	ENOG4105DIA	mandelate racemase muconate lactonizing
D1818_10835	ENOG4105CHR	reductase
D1818_10845	ENOG4105CPQ	Dehydrogenase
D1818_10865	ENOG41061MV	Arylsulfatase
D1818_10880	ENOG4108I7H	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D1818_10885	ENOG4105CUG	Oligopeptidase b
D1818_10895	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
D1818_10900	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
D1818_11075	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
D1818_11080	ENOG4105W5Q	DNA repair protein (RadC
D1818_11130	ENOG4105NI8	Cytosine-specific methyltransferase
D1818_11145	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
D1818_11155	ENOG4105C2N	RNA methyltransferase TrmH family group 3
D1818_11170	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D1818_11220	ENOG4105DY8	decarboxylase
D1818_11240	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
D1818_11250	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
D1818_11255	ENOG41086DT	Membrane protein of unknown function
D1818_11265	ENOG4105ISI	outer membrane protein, OMPP1 FadL TodX family
D1818_11270	ENOG4105EV9	Alpha Beta Hydrolase
D1818_11275	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
D1818_11285	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
D1818_11295	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
D1818_11315	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
D1818_11325	ENOG4108NEV	two component transcriptional regulator, LytTR family
D1818_11330	ENOG4108HRK	Histidine kinase
D1818_11365	ENOG41072GX	Peptidase M22 Glycoprotease
D1818_11370	ENOG410624X	efflux transporter, rnd family, mfp subunit
D1818_11380	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
D1818_11385	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D1818_11390	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D1818_11395	ENOG4105C19	ABC transporter
D1818_11410	ENOG4108SJC	Membrane
D1818_11415	ENOG4108KF3	Electron transport protein SCO1 SenC
D1818_11435	ENOG4105CCU	oxidase (Subunit III)
D1818_11440	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
D1818_11465	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
D1818_11475	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
D1818_11480	ENOG4105C6K	Malic enzyme
D1818_11485	ENOG4105E53	ec 3.2.1.28
D1818_11495	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
D1818_11505	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
D1818_11515	ENOG4105BZ9	Cytochrome C oxidase, subunit I
D1818_11520	ENOG4105Z4T	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
D1818_11540	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
D1818_11545	ENOG4107SFQ	iron-sulfur binding
D1818_11560	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
D1818_11565	ENOG4105CHV	Transcription elongation factor NusA
D1818_11570	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
D1818_11595	ENOG4105K63	Thioredoxin
D1818_11605	ENOG4105C2M	dna polymerase I
D1818_11610	ENOG4105EE5	Membrane protein terC
D1818_11640	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
D1818_11645	ENOG4108UJD	30S ribosomal protein S9
D1818_11650	ENOG4105CE9	30S ribosomal protein S2
D1818_11655	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
D1818_11660	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
D1818_11665	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
D1818_11680	ENOG4105C5S	asparaginyl-tRNA synthetase
D1818_11700	ENOG4108HRK	Histidine kinase
D1818_11725	ENOG41087YS	Phage shock protein A
D1818_11730	ENOG4105K8R	UPF0145 protein
D1818_11765	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
D1818_11820	ENOG4105BZU	Histidine kinase
D1818_11825	ENOG4105WH1	Two component transcriptional regulator luxr family
D1818_11830	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D1818_11850	ENOG4109015	Biopolymer transport protein exbD tolR
D1818_11860	ENOG4109015	Biopolymer transport protein exbD tolR
D1818_11880	ENOG4105HDK	L-asparaginase
D1818_11885	ENOG4105F8V	Hydrolase, tatD family
D1818_11930	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
D1818_11950	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D1818_11955	ENOG4105DC1	bifunctional purine biosynthesis protein purh
D1818_11960	ENOG4105DFF	Rod shape-determining protein mreb
D1818_11980	ENOG4105CNI	cell division protein FtsW
D1818_12035	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
D1818_12040	ENOG4105CN1	protease
D1818_12045	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
D1818_12055	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D1818_12060	ENOG4107TT5	NLP P60 protein
D1818_12070	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
D1818_12095	ENOG4105DUX	Transporter
D1818_12100	ENOG4105C5Z	peptidase
D1818_12115	ENOG4105E08	Glycoside hydrolase, family 9
D1818_12120	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D1818_12125	ENOG4105C7S	Dehydrogenase
D1818_12175	ENOG4105BZS	acriflavin resistance protein
D1818_12185	ENOG4105C27	TonB-dependent Receptor Plug
D1818_12190	ENOG4105C9M	aspartyl-trna synthetase
D1818_12200	ENOG4107T9C	Alpha amylase catalytic region
D1818_12210	ENOG4105VEQ	Cold shock protein
D1818_12235	ENOG4108Z6B	deaminase
D1818_12240	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
D1818_12245	ENOG4105EY9	peptidase S8 and S53, subtilisin, kexin, sedolisin
D1818_12255	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
D1818_12270	ENOG4105CDV	Ompa motb domain protein
D1818_12300	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
D1818_12320	ENOG4105CN1	protease
D1818_12340	ENOG4105D2H	Uronic isomerase
D1818_12350	ENOG4105EP8	Glycosyl Hydrolase Family 88
D1818_12360	ENOG4105C27	TonB-dependent Receptor Plug
D1818_12370	ENOG4105DMW	Dehydrogenase reductase
D1818_12375	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
D1818_12385	ENOG4105CHR	reductase
D1818_12400	ENOG4108RTU	Aldolase
D1818_12405	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
D1818_12415	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D1818_12455	ENOG4107QWR	cellulase (EC 3.2.1.4)
D1818_12500	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
D1818_12505	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
D1818_12510	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
D1818_12515	ENOG4105DTN	riboflavin biosynthesis protein ribF
D1818_12525	ENOG4105BZU	Histidine kinase
D1818_12555	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
D1818_12585	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
D1818_12590	ENOG4105CJW	magnesium transporter
D1818_12620	ENOG4105NVB	glycoside hydrolase, family 19
D1818_12625	ENOG4108JQ1	Dehydrogenase
D1818_12635	ENOG4105WH1	Two component transcriptional regulator luxr family
D1818_12660	ENOG4108ZT1	Transcriptional regulator
D1818_12680	ENOG4108Z7F	N-acetyltransferase
D1818_12685	ENOG4108UXE	Protein tyrosine phosphatase
D1818_12700	ENOG4105CFH	Aspartokinase
D1818_12710	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
D1818_12730	ENOG4105BZU	Histidine kinase
D1818_12740	ENOG4107T0X	DNA ligase
D1818_12745	ENOG4107RYT	DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair (By similarity)
D1818_12750	ENOG4107QRT	dEAD DEAH box helicase
D1818_12760	ENOG4107EPV	Aminotransferase class V
D1818_12770	ENOG4108JA2	transcriptioN-repair coupling factor
D1818_12825	ENOG4107S1E	Beta-lactamase
D1818_12840	ENOG4105CPC	Aldo Keto reductase
D1818_12845	ENOG41080R2	UPF0102 protein
D1818_12850	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
D1818_12875	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
D1818_12895	ENOG4105DGU	Histone deacetylase
D1818_12900	ENOG4106R7G	Glycoside hydrolase family 5
D1818_12915	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D1818_12935	ENOG4105E33	succinate dehydrogenase
D1818_12960	ENOG4105CHM	Aminotransferase
D1818_13000	ENOG41080ZE	Adenylate cyclase
D1818_13015	ENOG4108JQB	penicillin-binding protein 1C
D1818_13020	ENOG4105BZU	Histidine kinase
D1818_13025	ENOG4105BZU	Histidine kinase
D1818_13045	ENOG41061CK	Antibiotic biosynthesis monooxygenase
D1818_13055	ENOG4105DN3	alpha-2-macroglobulin domain protein
D1818_13160	ENOG4108Y6J	UPF0403 protein
D1818_13165	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
D1818_13205	ENOG4105CE1	Ferrous iron transport protein b
D1818_13220	ENOG4108KF3	Electron transport protein SCO1 SenC
D1818_13225	ENOG4105DZP	Membrane-associated zinc metalloprotease
D1818_13240	ENOG4105EMU	Dehydrogenase
D1818_13250	ENOG4105CK7	Sodium proline symporter
D1818_13255	ENOG4105C27	TonB-dependent Receptor Plug
D1818_13300	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D1818_13360	ENOG4105D05	Receptor
D1818_13365	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
D1818_13375	ENOG4107R37	Glutamate dehydrogenase
D1818_13380	ENOG4105C28	cystathionine
D1818_13420	ENOG4105CHR	reductase
D1818_13425	ENOG4105FFC	UPF0187 protein
D1818_13430	ENOG4105DNZ	Alpha Beta Hydrolase
D1818_13455	ENOG4105D3R	alkyl hydroperoxide reductase
D1818_13460	ENOG4107QP7	CoA-transferase subunit A
D1818_13465	ENOG4108JQC	penicillin-binding protein 1A
D1818_13470	ENOG4108JQC	penicillin-binding protein 1A
D1818_13475	ENOG410647Z	gliding motility-associated lipoprotein GldH
D1818_13480	ENOG4105MA4	psp1 domain protein
D1818_13485	ENOG4105C72	UPF0176 protein
D1818_13490	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
D1818_13500	ENOG4105EMN	RNA polymerase sigma factor
D1818_13515	ENOG4105C31	Tryptophanyl-tRNA synthetase
D1818_13545	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
D1818_13590	ENOG4105E96	Colicin v production protein
D1818_13625	ENOG4107QVM	von Willebrand factor, type A
D1818_13630	ENOG4108WS4	fmn reductase
D1818_13635	ENOG4107QVM	von Willebrand factor, type A
D1818_13650	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D1818_13655	ENOG4105EMU	Dehydrogenase
D1818_13700	ENOG4108VAC	response regulator
D1818_13705	ENOG4108HRK	Histidine kinase
D1818_13710	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
D1818_13740	ENOG4105D52	delta-aminolevulinic acid dehydratase
D1818_13745	ENOG4105CJ1	ABC, transporter
D1818_13820	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
D1818_13825	ENOG4105EXN	Sulfate transport protein CysZ
D1818_13835	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
D1818_13845	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
D1818_13850	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
D1818_13860	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
D1818_13885	ENOG4105DSJ	YicC domain protein
D1818_13890	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
D1818_13895	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
D1818_13910	ENOG4105E39	Enoyl-CoA hydratase
D1818_13925	ENOG4108JQ6	ABC transporter
D1818_13960	ENOG4105C26	Dehydrogenase
D1818_13965	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
D1818_13980	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
D1818_13985	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
D1818_14000	ENOG4105KHC	sulfurtransferase
D1818_14005	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
D1818_14025	ENOG4105NAU	thioesterase Superfamily protein
D1818_14050	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
D1818_14055	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
D1818_14085	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
D1818_14090	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
D1818_14095	ENOG4107Z4P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D1818_14100	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
D1818_14105	ENOG4105VHG	atp synthase
D1818_14110	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
D1818_14135	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D1818_14150	ENOG4105CT3	Monooxygenase
D1818_14165	ENOG4105C8Y	Acetylornithine aminotransferase
D1818_14200	ENOG4107QVI	Methyltransferase, type 11
D1818_14245	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
D1818_14260	ENOG4105DVP	Adenine-specific
D1818_14280	ENOG4107QNG	Phosphoribosylglycinamide synthetase
D1818_14285	ENOG4105PF3	O-Antigen polymerase
D1818_14295	ENOG4108IAJ	Nad-dependent epimerase dehydratase
D1818_14300	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
D1818_14310	ENOG4105JNK	Glycosyl transferase (Group 1
D1818_14315	ENOG4108DMA	Nad-dependent epimerase dehydratase
D1818_14320	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
D1818_14325	ENOG4108TJN	glycosyl transferase group 1
D1818_14350	ENOG4105PSV	Polysaccharide Biosynthesis Protein
D1818_14360	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
D1818_14365	ENOG4105D3Q	Sugar transferase
D1818_14395	ENOG4107R0I	Cell wall formation (By similarity)
D1818_14410	ENOG4108IJ1	Dehydrogenase
D1818_14415	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
D1818_14430	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
D1818_14465	ENOG4108K5P	(LipO)protein
D1818_14470	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
D1818_14495	ENOG4105E9H	Lytic Murein transglycosylase
D1818_14500	ENOG4105BZA	Phosphoglycerate kinase
D1818_14505	ENOG4107QRG	dna polymerase iii
D1818_14550	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
D1818_14555	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
D1818_14565	ENOG4105EEF	Alkane 1-monooxygenase
D1818_14570	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
D1818_14575	ENOG4105EPW	hflc protein
D1818_14585	ENOG4105DIJ	Phosphoethanolamine transferase
D1818_14590	ENOG4105CX6	glutaminyL-tRNA synthetase
D1818_14615	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
D1818_14630	ENOG4108YZG	isomerase
D1818_14635	ENOG4105PGM	cation diffusion facilitator family transporter
D1818_14640	ENOG4107YB6	acetyltransferase, (GNAT) family
D1818_14645	ENOG4105CN1	protease
D1818_14650	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
D1818_14665	ENOG4105C8F	Beta-lactamase domain protein
D1818_14720	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
D1818_14745	ENOG4105VG1	fes assembly suf system protein
D1818_14750	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
D1818_14755	ENOG4105C9B	Cysteine desulfurase
D1818_14795	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
D1818_14800	ENOG4105CA0	peroxidase
D1818_14830	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
D1818_14840	ENOG4107S9D	Alpha beta hydrolase
D1818_14845	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
D1818_14860	ENOG4107T6F	Xaa-Pro aminopeptidase
D1818_14895	ENOG4105CA9	Pyruvate kinase
D1818_14905	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
D1818_14910	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D1818_14915	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
D1818_14920	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
D1818_14925	ENOG4108B1Q	Ribonuclease
D1818_14945	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
D1818_14950	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
D1818_14955	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
D1818_14960	ENOG4105CDV	Ompa motb domain protein
D1818_15045	ENOG4105CMG	Carbohydrate kinase
D1818_15050	ENOG4105C93	Xylose Isomerase
D1818_15055	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
D1818_15060	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
D1818_15065	ENOG4105ETE	Transcriptional regulator (LacI family
D1818_15070	ENOG4108ZJ4	polysaccharide deacetylase
D1818_15085	ENOG4105BZU	Histidine kinase
D1818_15095	ENOG4105C27	TonB-dependent Receptor Plug
D1818_15100	ENOG4105TT1	Ragb susd domain-containing protein
D1818_15110	ENOG4105CYP	glycoside hydrolase, family
D1818_15115	ENOG4105EK5	Glycoside hydrolase family 8
D1818_15200	ENOG4107R73	Mate efflux family protein
D1818_15210	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
D1818_15215	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
D1818_15225	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D1818_15245	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
D1818_15250	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
D1818_15255	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
D1818_15260	ENOG4107T8J	thymidine kinase
D1818_15300	ENOG4105ENE	Histidine kinase
D1818_15305	ENOG4105WH1	Two component transcriptional regulator luxr family
D1818_15315	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
D1818_15325	ENOG4105CPT	Alpha beta hydrolase
D1818_15345	ENOG410626B	catechol 1,2-dioxygenase
D1818_15350	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
D1818_15360	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
D1818_15365	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
D1818_15370	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
D1818_15375	ENOG4105WXV	50S ribosomal protein L32
D1818_15385	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
D1818_15390	ENOG4108R6K	riboflavin synthase, subunit alpha
D1818_15405	ENOG4108ZVT	methylmalonyl-coA epimerase
D1818_15410	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
D1818_15415	ENOG4105D60	lipoprotein releasing system transmembrane protein
D1818_15420	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
D1818_15425	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
D1818_15430	ENOG4108HCJ	Hydrolase
D1818_15445	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
D1818_15485	ENOG4107QP8	phosphohexose isomerase
D1818_15495	ENOG4105HJ8	Catalyzes the oxidative cleavage of the L-tryptophan (L- Trp) pyrrole ring (By similarity)
D1818_15505	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
D1818_15515	ENOG4105F1J	Homogentisate 1,2-dioxygenase
D1818_15525	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
D1818_15535	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
D1818_15545	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
D1818_15550	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
D1818_15555	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
D1818_15580	ENOG4108AEY	RNA polymerase sigma factor
D1818_15585	ENOG4108UHE	carbonic anhydrase
D1818_15600	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
D1818_15605	ENOG4105C27	TonB-dependent Receptor Plug
D1818_15630	ENOG4105MJ2	Competence protein
D1818_15640	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
D1818_15665	ENOG4105DVE	abc transporter atp-binding protein
D1818_15680	ENOG4105CGK	Exodeoxyribonuclease III
D1818_15715	ENOG4105CPC	Aldo Keto reductase
D1818_15720	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
D1818_15735	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
D1818_15740	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
D1818_15745	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
D1818_15755	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
D1818_15780	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
D1818_15785	ENOG41082MC	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
D1818_15810	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
D1818_15820	ENOG4105C1J	atp-dependent rna helicase
D1818_15830	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D1818_15835	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
D1818_15840	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
D1818_15855	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D1818_15860	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
D1818_15905	ENOG4105Y3E	Modulates RecA activity (By similarity)
D1818_15945	ENOG4105C03	ribonuclease
D1818_15950	ENOG4105K70	DNA-binding protein
D1818_15955	ENOG4105CEN	a g-specific adenine glycosylase
D1818_15960	ENOG4108UUM	single-stranded DNA-binding protein
D1818_15965	ENOG4105C37	(CBS) domain
D1818_15975	ENOG4108594	Permease of the drug metabolite transporter
D1818_15985	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
D1818_15990	ENOG4105K46	50S ribosomal protein l27
D1818_16000	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
D1818_16015	ENOG4106Z1T	Nicotinamide Mononucleotide Transporter
D1818_16030	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
D1818_16040	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1818_16045	ENOG4105BZU	Histidine kinase
D1818_16060	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
D1818_16070	ENOG4105DWF	phosphomethylpyrimidine kinase
D1818_16075	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
D1818_16085	ENOG4105D41	biosynthesis protein thiH
D1818_16100	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
D1818_16120	ENOG4105BZU	Histidine kinase
D1818_16125	ENOG4105EW6	flavin reductase domain protein, FMN-binding
D1818_16135	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
D1818_16140	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
D1818_16145	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
D1818_16150	ENOG4107RE3	peptidase, S41
D1818_16165	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
D1818_16170	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
D1818_16185	ENOG4107QZC	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
D1818_16190	ENOG4107RJ9	Cell division protein FtsX
D1818_16195	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
D1818_16205	ENOG4105C8T	Leucyl-tRNA synthetase
D1818_16210	ENOG4105W3H	MtN3 and saliva related transmembrane protein
D1818_16225	ENOG4108VVK	transcriptional Regulator, AsnC
D1818_16240	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
D1818_16255	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
D1818_16260	ENOG4105CD3	dihydroorotase
D1818_16290	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
D1818_16340	ENOG4105C27	TonB-dependent Receptor Plug
D1818_16355	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D1818_16360	ENOG4105BZU	Histidine kinase
D1818_16365	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
D1818_16370	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
D1818_16435	ENOG4107YHX	fad dependent oxidoreductase
D1818_16445	ENOG4105W5Z	
D1818_16465	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
D1818_16635	ENOG4107S4Z	Activates expression of the rhaBAD and rhaT operons (By similarity)
D1818_16640	ENOG4107S1E	Beta-lactamase
D1818_16680	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
D1818_16685	ENOG4105CTU	Proline racemase
D1818_16695	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
D1818_16705	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
D1818_16735	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
D1818_16740	ENOG4105CSA	Coproporphyrinogen iii oxidase
D1818_16745	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
D1818_16805	ENOG4105C0B	DNA polymerase III (alpha subunit)
D1818_16820	ENOG4105K5M	30s ribosomal protein S16
D1818_16825	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
D1818_16830	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
D1818_16840	ENOG4105C1G	acyl-Coa dehydrogenase
D1818_16855	ENOG4108NIW	Leucine export protein LeuE
D1818_16865	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
D1818_16870	ENOG4105CBX	hi0933 family
D1818_16885	ENOG4107Z3H	Transcriptional regulator, TetR family
D1818_16890	ENOG4105KAV	tspo and mbr like protein
D1818_16925	ENOG4105FE9	pseudouridine synthase
D1818_16930	ENOG4105DY9	regulatoR
D1818_16965	ENOG4105CND	Glycosyl transferase, family 2
D1818_16970	ENOG4105C3Q	Glycosyl transferase, family 2
D1818_16980	ENOG4105BZU	Histidine kinase
D1818_16995	ENOG4108IFG	nitrite reductase, (NAD(P)H)
D1818_17055	ENOG41075H3	AraC family transcriptional regulator
D1818_17090	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D1818_17100	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
D1818_17110	ENOG4105C72	UPF0176 protein
D1818_17125	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
D1818_17130	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
D1818_17150	ENOG4105ETE	Transcriptional regulator (LacI family
D1818_17155	ENOG4105CG3	alpha amylase, catalytic region
D1818_17160	ENOG4105C27	TonB-dependent Receptor Plug
D1818_17200	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
D1818_17205	ENOG4105CIH	Imidazole acetol-phosphate transaminase
D1818_17210	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
D1818_17240	ENOG4105E4R	Precorrin-3B C17-methyltransferase
D1818_17245	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
D1818_17250	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
D1818_17255	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
D1818_17260	ENOG4105QUC	reductase
D1818_17265	ENOG4107UA7	cobalamin biosynthesis protein CbiD
D1818_17275	ENOG4105EET	magnesium chelatase
D1818_17280	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
D1818_17285	ENOG4108WBT	adenosyltransferase
D1818_17295	ENOG4105CTK	cobaltochelatase, cobn subunit
D1818_17305	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
D1818_17330	ENOG4105C37	(CBS) domain
D1818_17335	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
D1818_17340	ENOG4105CMR	udp-glucose 4-epimerase
D1818_17345	ENOG4107RUZ	Sss sodium solute transporter superfamily
D1818_17350	ENOG4108HMR	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
D1818_17370	ENOG4105C27	TonB-dependent Receptor Plug
D1818_17375	ENOG410811P	TRANSCRIPTIONAl REGULATOR GntR family
D1818_17385	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
D1818_17390	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
D1818_17405	ENOG4108IJF	Heavy metal efflux pump, CzcA
D1818_17445	ENOG4107QP3	malate synthase g
D1818_17460	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
D1818_17465	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
D1818_17485	ENOG4107SM7	Transcriptional regulator
D1818_17490	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
D1818_17500	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
D1818_17505	ENOG41088SP	formiminoglutamate hydrolase
D1818_17510	ENOG4105E6M	Sulphatase-modifying factor protein
D1818_17540	ENOG4105C5H	ABC transporter
D1818_17570	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
D1818_17575	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
D1818_17580	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D1818_17585	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D1818_17650	ENOG4105EMU	Dehydrogenase
D1818_17665	ENOG410874W	AraC family transcriptional regulator
D1818_17670	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
D1818_17685	ENOG4107USA	Thioredoxin
D1818_17705	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D1818_17730	ENOG4105DG6	mannose-6-phosphate isomerase
D1818_17735	ENOG4105CKK	Glycosyl transferase, family 2
D1818_17780	ENOG4105CKK	Glycosyl transferase, family 2
D1818_17800	ENOG4105DY9	regulatoR
D1818_17810	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
D1818_17815	ENOG4105BZU	Histidine kinase
D1818_17885	ENOG4105DY8	decarboxylase
D1818_17890	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
D1818_17900	ENOG4105DUU	IucA IucC family protein
D1818_17905	ENOG4105DUU	IucA IucC family protein
D1818_17915	ENOG41075H3	AraC family transcriptional regulator
D1818_17920	ENOG4108ESX	Receptor
D1818_17935	ENOG4105BZU	Histidine kinase
D1818_17940	ENOG4105BZU	Histidine kinase
D1818_17965	ENOG4107RET	Isocitrate lyase
D1818_17985	ENOG4105DY9	regulatoR
D1818_18005	ENOG4105BZG	amino acid carrier protein
D1818_18020	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
D1818_18035	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
D1818_18060	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
D1818_18120	ENOG4105MIR	Phenylalanine 4-monooxygenase
D1818_18140	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
D1818_18145	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
D1818_18150	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
D1818_18160	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
D1818_18165	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
D1818_18175	ENOG4108UKI	Enoyl-CoA hydratase
D1818_18180	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
D1818_18200	ENOG4105CHU	acetyl-coa acetyltransferase
D1818_18215	ENOG4105DXM	phenylacetic acid degradation protein
D1818_18235	ENOG4105CM2	brancheD-chain amino acid aminotransferase
D1818_18240	ENOG4105CPP	Dehydrogenase, E1 component
D1818_18320	ENOG4105C09	Bile acid
D1818_18380	ENOG4108IY8	ABC, transporter
D1818_18390	ENOG4106F1P	AAA ATPase, central domain protein
D1818_18420	ENOG4105CA0	peroxidase
D1818_18425	ENOG4105CA0	peroxidase
D1818_18455	ENOG4108S2Y	peptide Chain Release factor
D1818_18460	ENOG4105E0Y	RtcB Protein
D1818_18470	ENOG4108KPZ	tonB-dependent Receptor
D1818_18520	ENOG410756H	nucleotidyltransferase
D1818_18550	ENOG4105BZU	Histidine kinase
D1818_18575	ENOG4105CBC	glutamate synthase
D1818_18580	ENOG4108UUM	single-stranded DNA-binding protein
D1818_18640	ENOG4108JPW	Aminotransferase
D1818_18645	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
D1818_18655	ENOG4105E0C	molybdate abc transporter
D1818_18660	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D1818_18705	ENOG4107X35	defense response to bacterium
D1818_18710	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
D1818_18715	ENOG4105BZU	Histidine kinase
D1818_18745	ENOG4108Z12	YiaAB two helix domain-containing protein
D1818_18790	ENOG4105CRK	lysyL-tRNA synthetase
D1818_18845	ENOG4105PFC	Transcriptional regulator
D1818_18850	ENOG4105VPI	YqaE family transport protein
D1818_18865	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
D1818_18890	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
D1818_18930	ENOG4105C1G	acyl-Coa dehydrogenase
D1818_18940	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
D1818_18950	ENOG4109015	Biopolymer transport protein exbD tolR
D1818_18970	ENOG4105D64	Mechanosensitive ion channel
D1818_18980	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
D1818_18985	ENOG4105E6M	Sulphatase-modifying factor protein
D1818_19000	ENOG4105KG3	cytidine deaminase
D1818_19005	ENOG4107R0V	Pyruvate dehydrogenase
D1818_19025	ENOG4105EMU	Dehydrogenase
D1818_19045	ENOG4105CP2	von willebrand factor, type a
D1818_19055	ENOG4105CP2	von willebrand factor, type a
D1818_19110	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
D1818_19115	ENOG4105J7D	transcriptional regulator
D1818_19125	ENOG4107R8N	Glycosyl transferase, family 2
D1818_19135	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
D1818_19240	ENOG4105CR4	methylisocitrate lyase
D1818_19245	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
D1818_19250	ENOG4105NIV	Esterase
D1818_19260	ENOG4105ETT	transcriptional Regulator, LysR family
D1818_19265	ENOG4108J53	cell adhesion domain-containing protein
D1818_19275	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
D1818_19280	ENOG4108V1T	peptidylprolyl cis-trans isomerase
D1818_19290	ENOG4105DVT	helicase
D1818_19300	ENOG4108ZIS	hydrolase, family 16
D1818_19305	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D1818_19335	ENOG4105ECP	epimerase
D1818_19345	ENOG4107QVI	Methyltransferase, type 11
D1818_19375	ENOG4105DGW	oligopeptidase A
D1818_19380	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
D1818_19385	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
D1818_19390	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
D1818_19395	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D1818_19410	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
D1818_19425	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
D1818_19465	ENOG41090PH	Protease synthase and sporulation negative regulatory protein pai 1
D1818_19550	ENOG4105CY0	Metallo-Beta-Lactamase
D1818_19605	ENOG4108VGI	doxx family
D1818_19625	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
D1818_19685	ENOG4105C27	TonB-dependent Receptor Plug
D1818_19735	ENOG4106HDC	
D1818_19740	ENOG4107S85	alpha-2-macroglobulin domain protein
D1818_19745	ENOG4105DFU	Cell wall formation (By similarity)
D1818_19765	ENOG4105W5Q	DNA repair protein (RadC
D1818_19795	ENOG4105D1H	recombination factor protein RarA
D1818_19805	ENOG4105C2N	RNA methyltransferase TrmH family group 3
D1818_19825	ENOG4105C27	TonB-dependent Receptor Plug
D1818_19840	ENOG4105C27	TonB-dependent Receptor Plug
D1818_19850	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
D1818_19855	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
D1818_19860	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
D1818_19865	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
D1818_19870	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
D1818_19875	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
D1818_19880	ENOG41082S5	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
D1818_19885	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D1818_19890	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
D1818_19895	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
D1818_19900	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
D1818_19905	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
D1818_19910	ENOG4105WNB	50s ribosomal protein l29
D1818_19915	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
D1818_19920	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
D1818_19925	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
D1818_19930	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D1818_19935	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
D1818_19940	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
D1818_19945	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
D1818_19950	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
D1818_19955	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
D1818_19960	ENOG41084HK	50S ribosomal protein L30
D1818_19965	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
D1818_19970	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
D1818_19975	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
D1818_19980	ENOG410864M	50S ribosomal protein L36
D1818_19985	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D1818_19990	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
D1818_19995	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
D1818_20000	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D1818_20005	ENOG4108ZT0	50S ribosomal protein l17
D1818_20010	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
D1818_20015	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
D1818_20035	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
D1818_20045	ENOG4105CGD	Nad-dependent epimerase dehydratase
D1818_20050	ENOG4105C75	arginyL-tRNA synthetase
D1818_20055	ENOG4105BZU	Histidine kinase
D1818_20100	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
D1818_20115	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
D1818_20120	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
D1818_20135	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
D1818_20140	ENOG4105BZ1	(ABC) transporter
D1818_20155	ENOG4105C8B	TIGR00159 family
D1818_20160	ENOG4105EEI	dihydropteroate synthase
D1818_20175	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
D1818_20180	ENOG4105CP7	Triose-phosphate isomerase
D1818_20185	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
D1818_20215	ENOG4108AEY	RNA polymerase sigma factor
D1818_20275	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
D1818_20300	ENOG4107XVH	Transcriptional regulator
D1818_20305	ENOG4105WPR	Transcriptional regulator, ARAC family
D1818_20385	ENOG4108RMU	ferritin dps family protein
D1818_20395	ENOG4107XVH	Transcriptional regulator
D1818_20425	ENOG4105D64	Mechanosensitive ion channel
D1818_20450	ENOG4105S64	Formate nitrite transporter
D1818_20470	ENOG4105D7N	magnesium and cobalt transport protein CorA
D1818_20485	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
D1818_20495	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
D1818_20530	ENOG4107R5B	glutamine synthetase
D1818_20555	ENOG4108WYR	Curli production assembly transport component, CsgF
D1818_20560	ENOG4105P8Q	Curli production assembly transport component CsgG
D1818_20570	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
D1818_20575	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
D1818_20585	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
D1818_20590	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
D1818_20595	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
D1818_20600	ENOG4105C8N	cysteinyl-tRNA synthetase
D1818_20605	ENOG4105EUJ	GTP cyclohydrolase i
D1818_20630	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
D1818_20645	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
D1818_20665	ENOG4105EGD	dinuclear metal center protein, YbgI family
D1818_20670	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
D1818_20675	ENOG4105BZU	Histidine kinase
D1818_20680	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D1818_20685	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
D1818_20705	ENOG4107R0I	Cell wall formation (By similarity)
D1818_20710	ENOG4105CHM	Aminotransferase
D1818_20725	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
D1818_20735	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
D1818_20740	ENOG4105KNE	Phosphatidate cytidylyltransferase
D1818_20750	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
D1818_20755	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
D1818_20770	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
D1818_20800	ENOG4105CHH	sulfate transporter
D1818_20845	ENOG4108ZI4	Glyoxalase Bleomycin resistance protein (Dioxygenase
D1818_20855	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
D1818_20860	ENOG4105CPF	Cell wall formation (By similarity)
D1818_20870	ENOG4105C34	Pseudouridine synthase
D1818_20880	ENOG4105CD3	dihydroorotase
D1818_20885	ENOG4105VEQ	Cold shock protein
D1818_20895	ENOG4105D1Q	UPF0246 protein
D1818_20905	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
D1818_20915	ENOG4105CH5	extracellular solute-binding protein, family 7
D1818_20920	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
D1818_20950	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
D1818_21015	ENOG4107RA9	decarboxylase
D1818_21020	ENOG4108XC3	NADH ubiquinone oxidoreductase
D1818_21040	ENOG4105ENE	Histidine kinase
D1818_21065	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
D1818_21070	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
D1818_21075	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
D1818_21085	ENOG4105DK0	Indole-3-glycerol phosphate synthase
D1818_21090	ENOG4108I0Q	anthranilate phosphoribosyltransferase
D1818_21095	ENOG4105DDQ	anthranilate synthase
D1818_21100	ENOG4105CRQ	synthase (Component I)
D1818_21115	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1818_21125	ENOG41085GJ	domain protein
D1818_21145	ENOG4105DR5	peptidase
D1818_21150	ENOG4105WH1	Two component transcriptional regulator luxr family
D1818_21175	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
D1818_21180	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
D1818_21200	ENOG4105C27	TonB-dependent Receptor Plug
D1818_21220	ENOG4105D5P	Methylmalonyl-coA mutase
D1818_21225	ENOG4105CPN	adenine deaminase
D1818_21250	ENOG4105BZG	amino acid carrier protein
D1818_21255	ENOG4105D64	Mechanosensitive ion channel
D1818_21285	ENOG4108YZA	Nitrogen regulatory protein pii
D1818_21290	ENOG41083GQ	Protein CrcB homolog
D1818_21305	ENOG4105EWM	Histidine kinase
D1818_21310	ENOG4105WH1	Two component transcriptional regulator luxr family
D1818_21340	ENOG4105CM2	brancheD-chain amino acid aminotransferase
D1818_21350	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
D1818_21355	ENOG4105ECP	epimerase
D1818_21365	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D1818_21370	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
D1818_21375	ENOG4108IUX	(ABC) transporter
D1818_21380	ENOG4105RHA	ABC transporter, permease
D1818_21385	ENOG4105EGS	Mechanosensitive ion channel
D1818_21395	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D1818_21405	ENOG4105CSR	polyphosphate kinase 2
D1818_21415	ENOG4105CYP	glycoside hydrolase, family
D1818_21420	ENOG4106R7G	Glycoside hydrolase family 5
D1818_21465	ENOG4107QI1	Mate efflux family protein
D1818_21495	ENOG4108JQC	penicillin-binding protein 1A
D1818_21510	ENOG4105DJT	lAO AO transport system ATPase
D1818_21520	ENOG4107VFM	Dehydrogenase
D1818_21560	ENOG4105EMN	RNA polymerase sigma factor
D1818_21595	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
D1818_21605	ENOG4108WBT	adenosyltransferase
D1818_21610	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
D1818_21695	ENOG4105DA5	(ABC) transporter
D1818_21735	ENOG4107RBD	ABC, transporter
D1818_21740	ENOG4107RPQ	ABC transporter
D1818_21745	ENOG4105DIK	(ABC) transporter
D1818_21750	ENOG4105DSE	periplasmic solute binding protein
D1818_21760	ENOG4107RPQ	ABC transporter
D1818_21770	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
D1818_21780	ENOG4105CEV	competence damage-inducible protein
D1818_21810	ENOG4105KDC	50s ribosomal protein l28
D1818_21815	ENOG41083ND	50S ribosomal protein L33
D1818_21825	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
D1818_21840	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
D1818_21845	ENOG4108RCM	Nitroreductase
D1818_21850	ENOG4105C2I	pirin domain protein
D1818_21860	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
D1818_21865	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
D1818_21880	ENOG4105DGW	oligopeptidase A
D1818_21895	ENOG41074B2	UPF0747 protein
D1818_21955	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
D1818_21970	ENOG4105VRT	cytoplasmic protein
D1818_21975	ENOG4105CI2	imidazolone-5-propionate hydrolase
D1818_21980	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
D1818_21990	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
D1818_22000	ENOG41090A1	ferritin
D1818_22050	ENOG4108DMH	HTH_ARAC
D1818_22075	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1818_22085	ENOG4105E2A	Dehydrogenase
D1818_22100	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D1818_22110	ENOG4108RCM	Nitroreductase
D1818_22135	ENOG4107S1E	Beta-lactamase
D1818_22140	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
D1818_22155	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
D1818_22165	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
D1818_22170	ENOG4107Y2X	deaminase
D1818_22185	ENOG4105VEQ	Cold shock protein
D1818_22190	ENOG4108YIQ	Alpha beta hydrolase
D1818_22245	ENOG4106CKV	Pap2 superfamily protein
D1818_22250	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D1818_22275	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
D1818_22285	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
D1818_22290	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D1818_22305	ENOG4107QIJ	Aconitate hydratase 2
D1818_22320	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
D1818_22350	ENOG4108UVJ	appr-1-p processing domain protein
D1818_22355	ENOG4108URH	decarboxylase
D1818_22360	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
D1818_22365	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
D1818_22390	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1818_22405	ENOG4105EWK	phytoene
D1818_22435	ENOG4108AEY	RNA polymerase sigma factor
D1818_22445	ENOG4105C27	TonB-dependent Receptor Plug
D1818_22450	ENOG4105DR5	peptidase
D1818_22470	ENOG4105BZU	Histidine kinase
D1818_22490	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
D1818_22495	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
D1818_22505	ENOG4105VEJ	Heat shock protein
D1818_22520	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
D1818_22525	ENOG4108HHA	Transketolase
D1818_22530	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
D1818_22545	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
D1818_22550	ENOG4105CDU	Replicative dna helicase
D1818_22565	ENOG4105C5R	Aminotransferase
D1818_22575	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
D1818_22580	ENOG4105CD3	dihydroorotase
D1818_22590	ENOG4105CIN	aminoacyl-histidine dipeptidase
D1818_22595	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
D1818_22605	ENOG4105SFS	phosphoesterase RecJ domain protein
D1818_22610	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
D1818_22630	ENOG4108SF5	RNA Polymerase
D1818_22650	ENOG4108S4H	thioesterase Superfamily protein
D1818_22665	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
D1818_22675	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
D1818_22685	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
D1818_22720	ENOG4105C3F	Signal peptidase i
D1818_22725	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
D1818_22735	ENOG4105FA0	parb-like partition protein
D1818_22740	ENOG4107QJE	Chromosome Partitioning Protein
D1818_22745	ENOG4107RAN	Peptidase, M16
D1818_22750	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
D1818_22755	ENOG4105D5P	Methylmalonyl-coA mutase
D1818_22780	ENOG4105DBI	uridine monophosphokinase
D1818_22800	ENOG4105D8V	Glucose sorbosone dehydrogenase
D1818_22825	ENOG4105CNT	hydrolase family 2
D1818_22835	ENOG4108J53	cell adhesion domain-containing protein
D1818_22860	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
D1818_22890	ENOG4105BZU	Histidine kinase
D1818_22930	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
D1818_22950	ENOG4105C27	TonB-dependent Receptor Plug
D1818_22965	ENOG4107URF	beta-phospho-glucomutase
D1818_22975	ENOG4108IUK	alpha amylase, catalytic
D1818_22980	ENOG4105CG3	alpha amylase, catalytic region
D1818_22990	ENOG4105CTQ	phosphohexokinase
D1818_23010	ENOG4105BZU	Histidine kinase
D1818_23025	ENOG4107QZF	nitrite reductase NADPH large subunit
D1818_23045	ENOG4107RNU	major facilitator superfamily MFS_1
D1818_23050	ENOG4105I5W	Transporter
D1818_23055	ENOG4105DG7	nitrate ABC transporter
D1818_23060	ENOG4105D7T	ABC transporter
D1818_23065	ENOG4105D7T	ABC transporter
D1818_23080	ENOG4105CRE	cytochrome C
D1818_23085	ENOG4105CRE	cytochrome C
D1818_23120	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
D1818_23150	ENOG4105BZU	Histidine kinase
D1818_23160	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
D1818_23165	ENOG4108ZAF	Molybdopterin
D1818_23175	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
D1818_23180	ENOG4105F4R	Transcriptional regulator mode
D1818_23185	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
D1818_23210	ENOG4105C9K	Endothelin-converting enzyme 1
D1818_23220	ENOG4105CFH	Aspartokinase
D1818_23225	ENOG4105C0P	Mg chelatase subunit ChlI
D1818_23310	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
D1818_23350	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
D1818_23360	ENOG4105P4J	Allophanate hydrolase, subunit 1
D1818_23385	ENOG4105WH1	Two component transcriptional regulator luxr family
D1818_23390	ENOG4105C01	Dihydroxy-acid dehydratase
D1818_23395	ENOG4105C7K	acetolactate synthase
D1818_23405	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
D1818_23415	ENOG4105C7B	Threonine dehydratase
D1818_23425	ENOG4108S4H	thioesterase Superfamily protein
D1818_23450	ENOG4105CGY	Dna recombination protein
D1818_23460	ENOG4105E0A	ABC, transporter
D1818_23465	ENOG4105EHG	Permease protein
D1818_23485	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
D1818_23495	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
D1818_23500	ENOG4108YZT	Adenosylcobinamide kinase
D1818_23505	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D1818_23535	ENOG4107QTF	adenylosuccinate lyase
D1818_23545	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
D1818_23555	ENOG4105BZU	Histidine kinase
D1818_23580	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
D1818_23600	ENOG4105C1J	atp-dependent rna helicase
D1818_23615	ENOG4105E1F	short-chain dehydrogenase reductase
D1818_23620	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
D1818_23630	ENOG4105C5H	ABC transporter
D1818_23690	ENOG4105C6K	Malic enzyme
D1818_23695	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
D1818_23725	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
D1818_23740	ENOG4105CNT	hydrolase family 2
D1818_23780	ENOG4105C9A	Phoh family
D1818_23785	ENOG4107QWK	SAICAR synthetase
D1818_23825	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
D1818_23830	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D1818_23835	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D1818_23840	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
D1818_23865	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
D1818_23880	ENOG4105EJQ	L-serine dehydratase
D1818_23885	ENOG4105CFG	Acts as a chaperone (By similarity)
D1818_23900	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
D1818_23915	ENOG4107QKV	phosphomannomutase
D1818_23920	ENOG4105D1S	lipid A biosynthesis
D1818_23935	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D1818_23970	ENOG4108RMU	ferritin dps family protein
D1818_23975	ENOG4108XXK	NUDIX hydrolase
D1818_23995	ENOG4107QN1	sodium solute
D1818_24005	ENOG4105BZU	Histidine kinase
D1818_24010	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
D1818_24015	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
D1818_24030	ENOG4105CN9	Peptidase m42 family protein
D1818_24065	ENOG4105BZU	Histidine kinase
D1818_24070	ENOG4108UT2	hemolysin iii
D1818_24090	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
D1818_24110	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
D1818_24115	ENOG4105EMN	RNA polymerase sigma factor
D1818_24125	ENOG4105C8Y	Acetylornithine aminotransferase
D1818_24180	ENOG4107QI6	Cysteine desulfurase
D1818_24190	ENOG4105DR5	peptidase
D1818_24210	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
D1818_24235	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D1818_24270	ENOG4105C1J	atp-dependent rna helicase
D1818_24275	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D1818_24295	ENOG4105BZU	Histidine kinase
D1818_24325	ENOG4105CNA	YD repeat protein
D1818_24435	ENOG4108QBX	(LipO)protein
D1818_24470	ENOG4105EUJ	GTP cyclohydrolase i
D1818_24490	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
D1818_24495	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
D1818_24500	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
D1818_24530	ENOG4105IIU	Aminopeptidase
D1818_24540	ENOG4105FJR	Lmbe family
D1818_24545	ENOG4105C28	cystathionine
D1818_24550	ENOG4105BZU	Histidine kinase
D1818_24555	ENOG4105D3R	alkyl hydroperoxide reductase
D1818_24560	ENOG41080RH	Thioredoxin
D1818_24570	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
D1818_24580	ENOG4105CNU	cell division protein FtsK
D1818_24595	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
D1818_24600	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
D1818_24610	ENOG4108RCM	Nitroreductase
D1818_24620	ENOG4105DFD	Na H antiporter
D1818_24630	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
D1818_24635	ENOG4108Z4R	3-deoxy-d-manno-octulosonate 8-phosphate phosphatase
D1818_24645	ENOG4105CRE	cytochrome C
D1818_24650	ENOG4107RUZ	Sss sodium solute transporter superfamily
D1818_24660	ENOG4105C27	TonB-dependent Receptor Plug
D1818_24680	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
D1818_24735	ENOG4105C84	Histidine ammonia-lyase
D1818_24745	ENOG4105CHR	reductase
D1818_24750	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D1818_24755	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
D1818_24770	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
D1818_24790	ENOG4105CJ1	ABC, transporter
D1818_24815	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
D1818_24820	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D1818_24830	ENOG4108ZJ4	polysaccharide deacetylase
D1818_24845	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
D1818_24885	ENOG4105DZS	Phenylacetate-CoA ligase
D1818_25000	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
D1818_25010	ENOG4105CTQ	phosphohexokinase
D1818_25015	ENOG4108Z5K	methylglyoxal synthase
D1818_25035	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
D1818_25045	ENOG4105DF6	Fe-S oxidoreductase
D1818_25055	ENOG4105DF6	Fe-S oxidoreductase
D1818_25065	ENOG4105D17	glycoside hydrolase, family 3 domain protein
D1818_25070	ENOG4107QM2	Aldo Keto reductase
D1818_25110	ENOG4107QHF	type ii secretion system protein e