locus-tag	class	description
HN014_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HN014_00015	ENOG4105QD8	tetrapyrrole corrin porphyrin
HN014_00025	ENOG4105HHA	aminodeoxychorismate lyase
HN014_00035	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HN014_00040	ENOG4105C0H	protease
HN014_00055	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HN014_00060	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HN014_00065	ENOG4105E9K	Isocitrate dehydrogenase
HN014_00070	ENOG4108WQI	RNA Polymerase
HN014_00095	ENOG41066YJ	Beta-lactamase
HN014_00110	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
HN014_00130	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HN014_00135	ENOG4105C0B	DNA polymerase III (alpha subunit)
HN014_00140	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HN014_00200	ENOG4105C22	threonyL-tRNA synthetase
HN014_00205	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HN014_00210	ENOG4105VJV	50s ribosomal protein L35
HN014_00215	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
HN014_00230	ENOG4108RWN	rrna methyltransferase
HN014_00245	ENOG4105I3K	Ferric uptake regulator, Fur family
HN014_00250	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HN014_00270	ENOG4105C8Y	Acetylornithine aminotransferase
HN014_00290	ENOG4105E2X	shikimate dehydrogenase
HN014_00310	ENOG4105C27	TonB-dependent Receptor Plug
HN014_00315	ENOG4107VQW	regulatoR
HN014_00320	ENOG41068WN	
HN014_00340	ENOG4105DXN	mazG family
HN014_00345	ENOG4105EA8	2-Nitropropane dioxygenase
HN014_00350	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HN014_00360	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HN014_00365	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HN014_00375	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HN014_00380	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HN014_00410	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HN014_00415	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HN014_00420	ENOG4107SF2	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
HN014_00445	ENOG4105CJ1	ABC, transporter
HN014_00460	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HN014_00495	ENOG41085GJ	domain protein
HN014_00505	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HN014_00520	ENOG4105CRQ	synthase (Component I)
HN014_00525	ENOG4105DDQ	anthranilate synthase
HN014_00530	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HN014_00535	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HN014_00540	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HN014_00545	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HN014_00550	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HN014_00590	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HN014_00605	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
HN014_00650	ENOG4105CH5	extracellular solute-binding protein, family 7
HN014_00655	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HN014_00660	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
HN014_00665	ENOG4105D1Q	UPF0246 protein
HN014_00670	ENOG41088YA	Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives (By similarity)
HN014_00675	ENOG4105VEQ	Cold shock protein
HN014_00680	ENOG4105C34	Pseudouridine synthase
HN014_00685	ENOG4105D9P	serine threonine protein kinase
HN014_00690	ENOG4105CPF	Cell wall formation (By similarity)
HN014_00695	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HN014_00715	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HN014_00725	ENOG4105CHH	sulfate transporter
HN014_00735	ENOG4108YZ4	nudix hydrolase
HN014_00740	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HN014_00755	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
HN014_00760	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HN014_00770	ENOG4105KNE	Phosphatidate cytidylyltransferase
HN014_00775	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
HN014_00785	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HN014_00805	ENOG4107R0I	Cell wall formation (By similarity)
HN014_00820	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HN014_00825	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HN014_00830	ENOG4105BZU	Histidine kinase
HN014_00835	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HN014_00840	ENOG4105EGD	dinuclear metal center protein, YbgI family
HN014_00855	ENOG4108ZT1	Transcriptional regulator
HN014_00875	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
HN014_00890	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HN014_00910	ENOG4105EUJ	GTP cyclohydrolase i
HN014_00915	ENOG4105C8N	cysteinyl-tRNA synthetase
HN014_00925	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HN014_00930	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HN014_00990	ENOG4105E4G	Type IV pilus
HN014_00995	ENOG4107QHF	type ii secretion system protein e
HN014_01005	ENOG4106855	Competence protein
HN014_01060	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HN014_01070	ENOG4105P8Q	Curli production assembly transport component CsgG
HN014_01110	ENOG4108HRK	Histidine kinase
HN014_01115	ENOG4105DY9	regulatoR
HN014_01125	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
HN014_01235	ENOG4105CJ1	ABC, transporter
HN014_01245	ENOG4105C8N	cysteinyl-tRNA synthetase
HN014_01250	ENOG4105D05	Receptor
HN014_01270	ENOG4108M1A	Chitin-binding protein
HN014_01295	ENOG4105CHR	reductase
HN014_01360	ENOG4108HRK	Histidine kinase
HN014_01365	ENOG4108NEV	two component transcriptional regulator, LytTR family
HN014_01405	ENOG4105EUZ	Beta-lactamase domain protein
HN014_01440	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HN014_01445	ENOG4108HRK	Histidine kinase
HN014_01450	ENOG4108NEV	two component transcriptional regulator, LytTR family
HN014_01460	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HN014_01475	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HN014_01520	ENOG4108JA1	polyketide synthase
HN014_01525	ENOG4108JA1	polyketide synthase
HN014_01615	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HN014_01620	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
HN014_01625	ENOG4108MP6	LysR family Transcriptional regulator
HN014_01635	ENOG4105ECQ	AraC Family Transcriptional Regulator
HN014_01645	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
HN014_01655	ENOG4105CH6	catalase
HN014_01675	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HN014_01685	ENOG4105DFA	alanine racemase domain protein
HN014_01695	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
HN014_01710	ENOG4105DY8	decarboxylase
HN014_01715	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
HN014_01765	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
HN014_01770	ENOG4105CP7	Triose-phosphate isomerase
HN014_01775	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
HN014_01790	ENOG4105EEI	dihydropteroate synthase
HN014_01815	ENOG4105C8B	TIGR00159 family
HN014_01820	ENOG4108NEV	two component transcriptional regulator, LytTR family
HN014_01825	ENOG4105C2F	Histidine kinase
HN014_01835	ENOG4105BZ1	(ABC) transporter
HN014_01855	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HN014_01860	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HN014_01870	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HN014_01880	ENOG4105C75	arginyL-tRNA synthetase
HN014_01885	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
HN014_01895	ENOG41066UZ	arginase EC 3.5.3.1
HN014_01905	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HN014_01910	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HN014_01915	ENOG4108ZT0	50S ribosomal protein l17
HN014_01920	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HN014_01925	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HN014_01930	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HN014_01935	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HN014_01940	ENOG410864M	50S ribosomal protein L36
HN014_01945	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HN014_01950	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HN014_01955	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HN014_01960	ENOG41084HK	50S ribosomal protein L30
HN014_01965	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HN014_01970	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HN014_01975	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HN014_01980	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HN014_01985	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HN014_01990	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HN014_01995	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HN014_02000	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HN014_02005	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HN014_02010	ENOG4105WNB	50s ribosomal protein l29
HN014_02015	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HN014_02020	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HN014_02025	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HN014_02030	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
HN014_02035	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HN014_02040	ENOG41082S5	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HN014_02045	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HN014_02050	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HN014_02055	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HN014_02060	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HN014_02065	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HN014_02070	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HN014_02090	ENOG4105C27	TonB-dependent Receptor Plug
HN014_02110	ENOG4105C27	TonB-dependent Receptor Plug
HN014_02130	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HN014_02140	ENOG4105D1H	recombination factor protein RarA
HN014_02170	ENOG4105W5Q	DNA repair protein (RadC
HN014_02185	ENOG4105DFU	Cell wall formation (By similarity)
HN014_02190	ENOG4107S85	alpha-2-macroglobulin domain protein
HN014_02200	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
HN014_02205	ENOG41075H3	AraC family transcriptional regulator
HN014_02215	ENOG4105D7W	serine acetyltransferase
HN014_02225	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HN014_02230	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HN014_02235	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HN014_02240	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HN014_02245	ENOG4105DGW	oligopeptidase A
HN014_02285	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HN014_02320	ENOG4105DHJ	ABC, transporter
HN014_02365	ENOG4105IIU	Aminopeptidase
HN014_02370	ENOG4105C7S	Dehydrogenase
HN014_02385	ENOG4105E6M	Sulphatase-modifying factor protein
HN014_02390	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
HN014_02400	ENOG4105CWX	Alpha-1,2-mannosidase
HN014_02455	ENOG4109015	Biopolymer transport protein exbD tolR
HN014_02465	ENOG4105DKR	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
HN014_02475	ENOG4105C1G	acyl-Coa dehydrogenase
HN014_02480	ENOG4105EPC	oxidoreductase
HN014_02540	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HN014_02555	ENOG4108KB1	transcriptional regulator, arac family
HN014_02570	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HN014_02580	ENOG4105VPI	YqaE family transport protein
HN014_02585	ENOG4105WH1	Two component transcriptional regulator luxr family
HN014_02600	ENOG4105CRK	lysyL-tRNA synthetase
HN014_02605	ENOG4105CKI	cobalamin synthesis protein
HN014_02630	ENOG4108Z12	YiaAB two helix domain-containing protein
HN014_02645	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HN014_02650	ENOG4107X35	defense response to bacterium
HN014_02715	ENOG4108NIW	Leucine export protein LeuE
HN014_02755	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HN014_02805	ENOG4105CN1	protease
HN014_02835	ENOG4108S2Y	peptide Chain Release factor
HN014_02840	ENOG4105E0Y	RtcB Protein
HN014_02850	ENOG4105FQP	Beta-lactamase
HN014_02880	ENOG4105CIG	ABC transporter
HN014_02895	ENOG4107XMK	single-stranded DNA-binding protein
HN014_02910	ENOG4108X0B	nad(p)h dehydrogenase (quinone)
HN014_02925	ENOG4107XGZ	Hydrolase
HN014_02930	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HN014_02940	ENOG4108QV3	biosynthesis protein
HN014_02945	ENOG4105D3Q	Sugar transferase
HN014_02955	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HN014_02995	ENOG4107TAE	Glycosyl transferase (Group 1
HN014_03010	ENOG4107R5Z	Oxidoreductase domain protein
HN014_03015	ENOG4105J5G	Transferase hexapeptide repeat containing protein
HN014_03035	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HN014_03040	ENOG4105CPP	Dehydrogenase, E1 component
HN014_03045	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HN014_03050	ENOG4105C7S	Dehydrogenase
HN014_03070	ENOG4105DXM	phenylacetic acid degradation protein
HN014_03075	ENOG4105CHU	acetyl-coa acetyltransferase
HN014_03090	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HN014_03095	ENOG4108UKI	Enoyl-CoA hydratase
HN014_03100	ENOG4108ZA2	phenylacetate-CoA oxygenase PaaJ subunit
HN014_03105	ENOG4105D9S	phenylacetate-CoA oxygenase PaaI subunit
HN014_03110	ENOG4105N76	Phenylacetate-CoA oxygenase, subunit
HN014_03115	ENOG4105CRS	phenylacetate-CoA oxygenase PaaG subunit
HN014_03120	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HN014_03135	ENOG4105MIR	Phenylalanine 4-monooxygenase
HN014_03150	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HN014_03185	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HN014_03195	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HN014_03210	ENOG4105BZU	Histidine kinase
HN014_03220	ENOG4105BZU	Histidine kinase
HN014_03230	ENOG4105DY9	regulatoR
HN014_03275	ENOG4105CKK	Glycosyl transferase, family 2
HN014_03280	ENOG4105BZG	amino acid carrier protein
HN014_03350	ENOG4105C0H	protease
HN014_03360	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HN014_03390	ENOG4105C27	TonB-dependent Receptor Plug
HN014_03425	ENOG4105CA0	peroxidase
HN014_03460	ENOG4108NEV	two component transcriptional regulator, LytTR family
HN014_03465	ENOG4105C2F	Histidine kinase
HN014_03475	ENOG4105D29	Helix-turn-helix type 11 domain protein
HN014_03485	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
HN014_03530	ENOG4105DA5	(ABC) transporter
HN014_03565	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HN014_03570	ENOG4108ZAF	Molybdopterin
HN014_03580	ENOG41080H2	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
HN014_03590	ENOG4105F4R	Transcriptional regulator mode
HN014_03595	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HN014_03600	ENOG4108W6G	cytochrome C
HN014_03605	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
HN014_03615	ENOG4105CRE	cytochrome C
HN014_03625	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
HN014_03640	ENOG4107SFQ	iron-sulfur binding
HN014_03665	ENOG4105BZU	Histidine kinase
HN014_03670	ENOG4105BZU	Histidine kinase
HN014_03890	ENOG4105DY9	regulatoR
HN014_03950	ENOG4107QHF	type ii secretion system protein e
HN014_03960	ENOG4106855	Competence protein
HN014_04005	ENOG4105DZR	Type I site-specific deoxyribonuclease
HN014_04015	ENOG4108HFV	
HN014_04120	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HN014_04385	ENOG4107QUV	Domain protein
HN014_04480	ENOG4108U05	Transcriptional regulator
HN014_04510	ENOG4107QHF	type ii secretion system protein e
HN014_04605	ENOG4105IBP	Cyclic peptide transporter
HN014_04625	ENOG4108NQ3	Phosphatidylinositol-specific phospholipase C
HN014_04645	ENOG4105C5H	ABC transporter
HN014_04675	ENOG4105E6M	Sulphatase-modifying factor protein
HN014_04685	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
HN014_04695	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HN014_04700	ENOG4108JU7	Transcriptional regulator
HN014_04720	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HN014_04725	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HN014_04745	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HN014_04750	ENOG4105C59	p-type ATPase
HN014_04765	ENOG4108IJF	Heavy metal efflux pump, CzcA
HN014_04780	ENOG4105CMR	udp-glucose 4-epimerase
HN014_04795	ENOG4107RCQ	(CBS) domain
HN014_04820	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HN014_04835	ENOG4105E0X	reductase
HN014_04840	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HN014_04845	ENOG4105CNG	UPF0061 protein
HN014_04850	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HN014_04880	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HN014_04905	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
HN014_04915	ENOG4107QXV	Phosphate transporter
HN014_04930	ENOG4105W06	Cupin 2, conserved barrel domain protein
HN014_04935	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
HN014_05015	ENOG4105CND	Glycosyl transferase, family 2
HN014_05025	ENOG4105FE9	pseudouridine synthase
HN014_05060	ENOG4105KAV	tspo and mbr like protein
HN014_05065	ENOG4107Z3H	Transcriptional regulator, TetR family
HN014_05080	ENOG4105CBX	hi0933 family
HN014_05085	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
HN014_05100	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
HN014_05105	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HN014_05110	ENOG4105K5M	30s ribosomal protein S16
HN014_05120	ENOG4105C0B	DNA polymerase III (alpha subunit)
HN014_05155	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HN014_05160	ENOG4105CSA	Coproporphyrinogen iii oxidase
HN014_05180	ENOG4105MSB	protein, conserved in bacteria
HN014_05200	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HN014_05215	ENOG4105CTU	Proline racemase
HN014_05220	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HN014_05225	ENOG4105DC7	peptidase M24
HN014_05270	ENOG4108KF3	Electron transport protein SCO1 SenC
HN014_05290	ENOG4108NEV	two component transcriptional regulator, LytTR family
HN014_05295	ENOG4108HRK	Histidine kinase
HN014_05310	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
HN014_05315	ENOG4105ETE	Transcriptional regulator (LacI family
HN014_05320	ENOG4105E2D	ec 3.2.1.52
HN014_05335	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HN014_05350	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN014_05380	ENOG4105C27	TonB-dependent Receptor Plug
HN014_05415	ENOG4105D05	Receptor
HN014_05445	ENOG4105C1J	atp-dependent rna helicase
HN014_05460	ENOG4105C27	TonB-dependent Receptor Plug
HN014_05485	ENOG4107YZX	Universal stress protein
HN014_05495	ENOG4107TPS	domain protein
HN014_05505	ENOG4105C59	p-type ATPase
HN014_05510	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HN014_05520	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
HN014_05530	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
HN014_05535	ENOG4105C58	cytochrome c oxidase accessory protein ccog
HN014_05560	ENOG4105D4P	Coproporphyrinogen iii oxidase
HN014_05565	ENOG4107YZX	Universal stress protein
HN014_05570	ENOG4105ETX	regulatoR
HN014_05575	ENOG4105GR3	Histidine kinase
HN014_05625	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HN014_05630	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HN014_05635	ENOG4105BZU	Histidine kinase
HN014_05640	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN014_05700	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HN014_05705	ENOG4105K4T	epimerase
HN014_05715	ENOG4105CD3	dihydroorotase
HN014_05720	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
HN014_05735	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HN014_05750	ENOG4108VVK	transcriptional Regulator, AsnC
HN014_05770	ENOG4105C8T	Leucyl-tRNA synthetase
HN014_05775	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HN014_05780	ENOG4107RJ9	Cell division protein FtsX
HN014_05785	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HN014_05800	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HN014_05805	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HN014_05825	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HN014_05830	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
HN014_05835	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HN014_05845	ENOG4107XWI	flavin reductase domain protein, FMN-binding
HN014_05850	ENOG4105BZU	Histidine kinase
HN014_05870	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HN014_05880	ENOG4105D06	uba thif-type nad fad binding protein
HN014_05885	ENOG4105D41	biosynthesis protein thiH
HN014_05890	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HN014_05895	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HN014_05900	ENOG4105DWF	phosphomethylpyrimidine kinase
HN014_05910	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HN014_05925	ENOG4105BZU	Histidine kinase
HN014_05930	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HN014_05965	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HN014_05975	ENOG4105K46	50S ribosomal protein l27
HN014_05980	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HN014_06000	ENOG4108594	Permease of the drug metabolite transporter
HN014_06010	ENOG4105C37	(CBS) domain
HN014_06015	ENOG4108UUM	single-stranded DNA-binding protein
HN014_06020	ENOG4105CEN	a g-specific adenine glycosylase
HN014_06025	ENOG4105K70	DNA-binding protein
HN014_06030	ENOG4105C03	ribonuclease
HN014_06105	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HN014_06110	ENOG4107WD4	Releases the N-terminal proline from various substrates (By similarity)
HN014_06115	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HN014_06125	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HN014_06130	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
HN014_06150	ENOG4108T5G	Adenylate
HN014_06170	ENOG4105SA9	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (By similarity)
HN014_06175	ENOG4105CKK	Glycosyl transferase, family 2
HN014_06185	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HN014_06190	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HN014_06195	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HN014_06205	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
HN014_06210	ENOG4107RWD	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
HN014_06215	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
HN014_06230	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HN014_06240	ENOG4105CPC	Aldo Keto reductase
HN014_06255	ENOG4105D05	Receptor
HN014_06270	ENOG4105ER2	Ompa motb domain protein
HN014_06275	ENOG4105CGK	Exodeoxyribonuclease III
HN014_06280	ENOG4108IUZ	ABC transporter
HN014_06300	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
HN014_06310	ENOG4105MJ2	Competence protein
HN014_06320	ENOG4105CZ7	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HN014_06325	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HN014_06340	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HN014_06345	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
HN014_06355	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HN014_06360	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HN014_06365	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HN014_06370	ENOG4105D78	K07001 NTE family protein
HN014_06375	ENOG4105F1J	Homogentisate 1,2-dioxygenase
HN014_06380	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
HN014_06400	ENOG4107QP8	phosphohexose isomerase
HN014_06415	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
HN014_06425	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HN014_06430	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HN014_06440	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HN014_06445	ENOG4108ZVT	methylmalonyl-coA epimerase
HN014_06490	ENOG4108R6K	riboflavin synthase, subunit alpha
HN014_06495	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HN014_06505	ENOG4105WXV	50S ribosomal protein L32
HN014_06510	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HN014_06515	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HN014_06520	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HN014_06545	ENOG4108VKV	Monofunctional biosynthetic peptidoglycan transglycosylase
HN014_06565	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HN014_06605	ENOG4107T8J	thymidine kinase
HN014_06610	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HN014_06615	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
HN014_06620	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HN014_06635	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HN014_06645	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HN014_06655	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
HN014_06660	ENOG4108IPT	Naphthoate synthase
HN014_06665	ENOG4107QI1	Mate efflux family protein
HN014_06705	ENOG4105C4R	Atp-dependent dna helicase
HN014_06710	ENOG4105CDV	Ompa motb domain protein
HN014_06725	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HN014_06740	ENOG4108B1Q	Ribonuclease
HN014_06745	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HN014_06750	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HN014_06755	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HN014_06760	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HN014_06770	ENOG4105CA9	Pyruvate kinase
HN014_06785	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HN014_06815	ENOG4108VAC	response regulator
HN014_06830	ENOG4107T6F	Xaa-Pro aminopeptidase
HN014_06840	ENOG4105CA0	peroxidase
HN014_06860	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HN014_06885	ENOG4105CA0	peroxidase
HN014_06890	ENOG4108Z4V	iron-sulfur cluster assembly
HN014_06935	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HN014_06940	ENOG4105VG1	fes assembly suf system protein
HN014_06975	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HN014_06980	ENOG4105ENX	hydrolase
HN014_06985	ENOG4105CN8	Transcriptional regulator
HN014_07005	ENOG4105C8F	Beta-lactamase domain protein
HN014_07020	ENOG41086JU	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HN014_07025	ENOG4105CN1	protease
HN014_07035	ENOG4108YZG	isomerase
HN014_07050	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HN014_07070	ENOG4105KRF	dihydroneopterin aldolase
HN014_07075	ENOG4105CX6	glutaminyL-tRNA synthetase
HN014_07085	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HN014_07090	ENOG4105EEF	Alkane 1-monooxygenase
HN014_07100	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HN014_07105	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HN014_07160	ENOG4105BZA	Phosphoglycerate kinase
HN014_07165	ENOG4105E9H	Lytic Murein transglycosylase
HN014_07180	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HN014_07185	ENOG4105FRN	stage II sporulation protein
HN014_07205	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
HN014_07210	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
HN014_07220	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
HN014_07225	ENOG4107QQG	Dehydrogenase
HN014_07265	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HN014_07270	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
HN014_07280	ENOG4105C12	Phosphoribosylglycinamide synthetase
HN014_07300	ENOG4105DKP	glycosyl transferase, family 9
HN014_07340	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
HN014_07350	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
HN014_07355	ENOG4107Z4P	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HN014_07360	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HN014_07365	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
HN014_07390	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HN014_07420	ENOG4108ZHR	arsR family transcriptional regulator
HN014_07425	ENOG4108S4H	thioesterase Superfamily protein
HN014_07445	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
HN014_07450	ENOG4105KHC	sulfurtransferase
HN014_07460	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HN014_07470	ENOG4105C3W	Catalyzes the oxidative ring opening of 3- hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate (By similarity)
HN014_07480	ENOG4105C26	Dehydrogenase
HN014_07520	ENOG4108JPV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HN014_07530	ENOG4106032	Glutathionylspermidine synthase
HN014_07535	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
HN014_07550	ENOG4105EMU	Dehydrogenase
HN014_07555	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HN014_07575	ENOG4107QVM	von Willebrand factor, type A
HN014_07605	ENOG4108V9Q	carbonic anhydrase
HN014_07610	ENOG4105CHH	sulfate transporter
HN014_07640	ENOG4105EMN	RNA polymerase sigma factor
HN014_07665	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HN014_07690	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HN014_07695	ENOG4105BZU	Histidine kinase
HN014_07715	ENOG4108WQI	RNA Polymerase
HN014_07725	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HN014_07735	ENOG4105MA4	psp1 domain protein
HN014_07740	ENOG410647Z	gliding motility-associated lipoprotein GldH
HN014_07745	ENOG4108JQC	penicillin-binding protein 1A
HN014_07750	ENOG4107QP7	CoA-transferase subunit A
HN014_07755	ENOG4105D3R	alkyl hydroperoxide reductase
HN014_07765	ENOG4108JQ6	ABC transporter
HN014_07775	ENOG4105E39	Enoyl-CoA hydratase
HN014_07780	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HN014_07785	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HN014_07790	ENOG4105DSJ	YicC domain protein
HN014_07805	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HN014_07820	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HN014_07825	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HN014_07835	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HN014_07840	ENOG4105EXN	Sulfate transport protein CysZ
HN014_07845	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
HN014_07885	ENOG4105CJ1	ABC, transporter
HN014_07890	ENOG4105D52	delta-aminolevulinic acid dehydratase
HN014_07895	ENOG4105F1N	DNA alkylation repair
HN014_08230	ENOG4105C28	cystathionine
HN014_08240	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
HN014_08245	ENOG4105D05	Receptor
HN014_08280	ENOG4105CE1	Ferrous iron transport protein b
HN014_08295	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HN014_08305	ENOG4108Y6J	UPF0403 protein
HN014_08340	ENOG4105D44	asparaginase
HN014_08345	ENOG4105DN3	alpha-2-macroglobulin domain protein
HN014_08355	ENOG4108JQB	penicillin-binding protein 1C
HN014_08380	ENOG4105CHM	Aminotransferase
HN014_08395	ENOG4105E33	succinate dehydrogenase
HN014_08400	ENOG4105IIU	Aminopeptidase
HN014_08415	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HN014_08425	ENOG4105DGU	Histone deacetylase
HN014_08430	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HN014_08455	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
HN014_08460	ENOG41080R2	UPF0102 protein
HN014_08480	ENOG4108JA2	transcriptioN-repair coupling factor
HN014_08510	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
HN014_08525	ENOG4105CFH	Aspartokinase
HN014_08535	ENOG4108UXE	Protein tyrosine phosphatase
HN014_08570	ENOG4108JQ1	Dehydrogenase
HN014_08575	ENOG41082W1	Cupin 2, conserved barrel domain protein
HN014_08580	ENOG4105CJW	magnesium transporter
HN014_08585	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HN014_08600	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HN014_08605	ENOG4105DZ2	Transcriptional regulator
HN014_08625	ENOG4105DTN	riboflavin biosynthesis protein ribF
HN014_08630	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HN014_08635	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HN014_08640	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HN014_08650	ENOG4105C0W	non-ribosomal peptide synthetase
HN014_08685	ENOG4105C0W	non-ribosomal peptide synthetase
HN014_08700	ENOG4105DA5	(ABC) transporter
HN014_08705	ENOG4105WPR	Transcriptional regulator, ARAC family
HN014_08750	ENOG4105CN1	protease
HN014_08765	ENOG41076UM	multiple antibiotic resistance (MarC)-related protein
HN014_08780	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HN014_08790	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
HN014_08795	ENOG4108Z6B	deaminase
HN014_08815	ENOG4105VEQ	Cold shock protein
HN014_08830	ENOG4105C9M	aspartyl-trna synthetase
HN014_08835	ENOG4105C27	TonB-dependent Receptor Plug
HN014_08845	ENOG41080XP	Cbs domain
HN014_08960	ENOG4108JJA	ABC, transporter
HN014_08995	ENOG4105BZS	acriflavin resistance protein
HN014_09010	ENOG4108IG5	Transcriptional regulator
HN014_09035	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HN014_09040	ENOG4105C7S	Dehydrogenase
HN014_09060	ENOG4105DUX	Transporter
HN014_09065	ENOG4105DUX	Transporter
HN014_09080	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
HN014_09085	ENOG4107TT5	NLP P60 protein
HN014_09090	ENOG4105BZU	Histidine kinase
HN014_09095	ENOG4105BZU	Histidine kinase
HN014_09100	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HN014_09110	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HN014_09115	ENOG4105CN1	protease
HN014_09120	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
HN014_09135	ENOG4105CNI	cell division protein FtsW
HN014_09140	ENOG4105CJN	penicillin-binding protein
HN014_09155	ENOG4105DFF	Rod shape-determining protein mreb
HN014_09160	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HN014_09190	ENOG4105F8V	Hydrolase, tatD family
HN014_09195	ENOG4105HDK	L-asparaginase
HN014_09245	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HN014_09255	ENOG4105BZU	Histidine kinase
HN014_09285	ENOG4105CGD	Nad-dependent epimerase dehydratase
HN014_09315	ENOG4105KG3	cytidine deaminase
HN014_09340	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HN014_09355	ENOG41087YS	Phage shock protein A
HN014_09375	ENOG4105C5S	asparaginyl-tRNA synthetase
HN014_09390	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HN014_09395	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HN014_09400	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HN014_09405	ENOG4105CE9	30S ribosomal protein S2
HN014_09410	ENOG4108UJD	30S ribosomal protein S9
HN014_09415	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HN014_09420	ENOG4107S1E	Beta-lactamase
HN014_09425	ENOG4105C2M	dna polymerase I
HN014_09460	ENOG4107YZX	Universal stress protein
HN014_09465	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
HN014_09470	ENOG4105CHV	Transcription elongation factor NusA
HN014_09475	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HN014_09490	ENOG4107SFQ	iron-sulfur binding
HN014_09515	ENOG4105E2S	oxidase) subunit II
HN014_09520	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HN014_09525	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HN014_09530	ENOG4105JZI	cytochrome P450
HN014_09535	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HN014_09540	ENOG4105C6K	Malic enzyme
HN014_09545	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HN014_09555	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HN014_09575	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HN014_09580	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HN014_09585	ENOG4105CCU	oxidase (Subunit III)
HN014_09605	ENOG4108KF3	Electron transport protein SCO1 SenC
HN014_09610	ENOG4108SJC	Membrane
HN014_09620	ENOG4105C19	ABC transporter
HN014_09625	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HN014_09630	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HN014_09635	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HN014_09645	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
HN014_09650	ENOG41072GX	Peptidase M22 Glycoprotease
HN014_09665	ENOG4105C7Z	Conserved Protein
HN014_09695	ENOG4108NEV	two component transcriptional regulator, LytTR family
HN014_09700	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HN014_09715	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HN014_09720	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HN014_09730	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HN014_09740	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HN014_09745	ENOG4105EV9	Alpha Beta Hydrolase
HN014_09750	ENOG4105ISI	outer membrane protein, OMPP1 FadL TodX family
HN014_09760	ENOG41086DT	Membrane protein of unknown function
HN014_09765	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HN014_09775	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HN014_09830	ENOG4105DY8	decarboxylase
HN014_09865	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HN014_09870	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HN014_09920	ENOG4105VTW	prevent-host-death family
HN014_09925	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
HN014_10025	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
HN014_10035	ENOG4105RKW	reductase (By
HN014_10070	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
HN014_10075	ENOG4105F0N	pyrophosphate phospho-hydrolase
HN014_10090	ENOG4105BZJ	Electron transfer flavoprotein
HN014_10095	ENOG4105C10	Electron transfer flavoprotein
HN014_10105	ENOG4105D9N	nucleoside
HN014_10110	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HN014_10125	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
HN014_10135	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HN014_10140	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HN014_10170	ENOG4105ZMH	deoxynucleoside kinase
HN014_10210	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HN014_10220	ENOG4105DWV	Homoserine O-trans-acetylase
HN014_10225	ENOG4105CFH	Aspartokinase
HN014_10230	ENOG4108UKZ	OsmC family
HN014_10235	ENOG4105C28	cystathionine
HN014_10255	ENOG4105C11	sulfate adenylyltransferase), subunit 2
HN014_10265	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HN014_10270	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HN014_10275	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HN014_10280	ENOG4105CAY	ferredoxin--nadp reductase
HN014_10285	ENOG4108ZIT	Ferredoxin, 2FE-2S
HN014_10290	ENOG4105C3R	Methionine synthase
HN014_10295	ENOG4105C3R	Methionine synthase
HN014_10300	ENOG4105SYT	Methylenetetrahydrofolate reductase
HN014_10315	ENOG4105CJ1	ABC, transporter
HN014_10320	ENOG4105EW9	transcriptional regulator AsnC family
HN014_10325	ENOG4105EXW	epimerase dehydratase
HN014_10330	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HN014_10340	ENOG4105CHM	Aminotransferase
HN014_10345	ENOG4105EVN	Prephenate dehydrogenase
HN014_10350	ENOG4108JPM	phospho-2-dehydro-3-deoxyheptonate aldolase
HN014_10355	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HN014_10360	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HN014_10380	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HN014_10390	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HN014_10420	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HN014_10430	ENOG4107RW9	nh(3)-dependent nad( ) synthetase
HN014_10445	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HN014_10455	ENOG4107YM1	mraZ protein
HN014_10460	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HN014_10470	ENOG4105CJN	penicillin-binding protein
HN014_10475	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HN014_10480	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HN014_10485	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HN014_10490	ENOG4105CNI	cell division protein FtsW
HN014_10495	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HN014_10500	ENOG4105DFU	Cell wall formation (By similarity)
HN014_10510	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HN014_10515	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HN014_10520	ENOG4105KTH	gatB Yqey
HN014_10600	ENOG4107QUV	Domain protein
HN014_10780	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HN014_10935	ENOG4107QUV	Domain protein
HN014_11015	ENOG4105DY9	regulatoR
HN014_11025	ENOG4105DY9	regulatoR
HN014_11030	ENOG4108HRK	Histidine kinase
HN014_11060	ENOG4107QIJ	Aconitate hydratase 2
HN014_11120	ENOG4105CNV	Aldolase
HN014_11135	ENOG4105EFA	4-hydroxyphenylacetate
HN014_11150	ENOG4105C26	Dehydrogenase
HN014_11160	ENOG4105CHM	Aminotransferase
HN014_11175	ENOG4105EQN	UPF0261 protein
HN014_11180	ENOG4105CUB	amino acid
HN014_11190	ENOG4105CI2	imidazolone-5-propionate hydrolase
HN014_11210	ENOG4105EPC	oxidoreductase
HN014_11260	ENOG41066YJ	Beta-lactamase
HN014_11305	ENOG4105EW9	transcriptional regulator AsnC family
HN014_11315	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HN014_11320	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HN014_11325	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HN014_11345	ENOG4105D60	lipoprotein releasing system transmembrane protein
HN014_11350	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HN014_11365	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HN014_11370	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HN014_11375	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HN014_11380	ENOG4106HB6	Alpha beta hydrolase
HN014_11405	ENOG4105ETE	Transcriptional regulator (LacI family
HN014_11410	ENOG4108KPZ	tonB-dependent Receptor
HN014_11415	ENOG4108RVA	ribokinase
HN014_11430	ENOG4105EAA	nucleoside
HN014_11435	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HN014_11440	ENOG4105ETE	Transcriptional regulator (LacI family
HN014_11460	ENOG4108WS4	fmn reductase
HN014_11495	ENOG4105EMN	RNA polymerase sigma factor
HN014_11515	ENOG4105BZU	Histidine kinase
HN014_11540	ENOG4107QP3	malate synthase g
HN014_11555	ENOG4105DJV	ribulose-phosphate 3-epimerase
HN014_11560	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HN014_11565	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HN014_11570	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HN014_11580	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HN014_11585	ENOG4105D2N	Aldolase
HN014_11595	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HN014_11605	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HN014_11610	ENOG4105C1A	potassium transporter peripheral membrane
HN014_11615	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HN014_11635	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HN014_11640	ENOG4105FFM	Resistance to gentamicin, tobramycin, and kanamycin. Tobramycin and kanamycin resistance is due to the ACC activity, specified by N-terminal region, and the gentamicin resistance is due to the APH activity encoded by the C-terminal region of the protein (By similarity)
HN014_11645	ENOG4105C26	Dehydrogenase
HN014_11660	ENOG4105NWN	ApaG protein
HN014_11675	ENOG4105DWQ	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HN014_11680	ENOG4108J5C	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HN014_11685	ENOG4106I92	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HN014_11690	ENOG4105F5D	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HN014_11695	ENOG4108IUB	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol (By similarity)
HN014_11705	ENOG4108XG2	Histidine kinase
HN014_11710	ENOG4105WH1	Two component transcriptional regulator luxr family
HN014_11725	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
HN014_11730	ENOG4105M4P	Tetr family transcriptional regulator
HN014_11750	ENOG4105CJ2	(LipO)protein
HN014_11755	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HN014_11770	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HN014_11775	ENOG4108K0D	peptidase, M48
HN014_11825	ENOG4105CKK	Glycosyl transferase, family 2
HN014_11835	ENOG4105CSV	Glutaminase
HN014_11840	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
HN014_11860	ENOG4108CSZ	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HN014_11875	ENOG4105CKY	Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively (By similarity)
HN014_11895	ENOG41063TF	transcriptional regulator (AraC
HN014_11900	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
HN014_11905	ENOG4105C26	Dehydrogenase
HN014_11920	ENOG4105FE9	pseudouridine synthase
HN014_11940	ENOG4105D7A	ATP-binding protein
HN014_11945	ENOG4105KME	endoribonuclease L-psp
HN014_11950	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HN014_11960	ENOG4105CAQ	asparagine synthetase
HN014_11970	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HN014_11985	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HN014_11995	ENOG4105CT7	inner membrane cred family protein
HN014_12030	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HN014_12035	ENOG4105CI3	gtp-binding protein typa
HN014_12045	ENOG4108Z7R	Chaperone CsaA
HN014_12055	ENOG4105CAK	Cell division ATP-binding protein ftsE
HN014_12070	ENOG4105EFZ	amidohydrolase
HN014_12125	ENOG4105WH1	Two component transcriptional regulator luxr family
HN014_12130	ENOG4105BZU	Histidine kinase
HN014_12135	ENOG4105EHZ	conserved protein UCP016719
HN014_12165	ENOG4107SVH	Potassium channel protein
HN014_12170	ENOG4105BZG	amino acid carrier protein
HN014_12180	ENOG4105C1G	acyl-Coa dehydrogenase
HN014_12185	ENOG41083X6	30S ribosomal protein S21
HN014_12190	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HN014_12220	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HN014_12240	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HN014_12245	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HN014_12250	ENOG4107VNI	ribosomal protein l10
HN014_12255	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HN014_12260	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HN014_12265	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HN014_12280	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HN014_12295	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HN014_12310	ENOG4105DG6	mannose-6-phosphate isomerase
HN014_12340	ENOG410667J	hydrolase
HN014_12355	ENOG4107XVH	Transcriptional regulator
HN014_12370	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HN014_12375	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HN014_12390	ENOG4107RJ1	sodium solute
HN014_12395	ENOG4105C19	ABC transporter
HN014_12440	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HN014_12445	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HN014_12455	ENOG4105VEJ	Heat shock protein
HN014_12475	ENOG4105DGW	oligopeptidase A
HN014_12485	ENOG41074B2	UPF0747 protein
HN014_12505	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HN014_12510	ENOG41068JE	domain protein
HN014_12520	ENOG4105VRT	cytoplasmic protein
HN014_12525	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HN014_12530	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HN014_12555	ENOG4105VN1	Heat shock protein
HN014_12560	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HN014_12600	ENOG4105JPG	D-isomer specific 2-hydroxyacid dehydrogenase
HN014_12730	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HN014_12750	ENOG4105C5H	ABC transporter
HN014_12755	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HN014_12760	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HN014_12765	ENOG4108IUZ	ABC transporter
HN014_12770	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HN014_12775	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HN014_12780	ENOG4105C2X	Arabinose 5-phosphate isomerase
HN014_12785	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HN014_12790	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
HN014_12810	ENOG4105BZ1	(ABC) transporter
HN014_12815	ENOG4107RDP	Dehydrogenase
HN014_12820	ENOG4107R6T	Involved in the transcription termination process (By similarity)
HN014_12830	ENOG4105VIE	preprotein translocase, subunit YajC
HN014_12835	ENOG4105D64	Mechanosensitive ion channel
HN014_12840	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
HN014_12860	ENOG4105KV4	Transcriptional regulator
HN014_12870	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HN014_12915	ENOG4108I5D	sulfate abc transporter
HN014_12920	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HN014_12925	ENOG41090A1	ferritin
HN014_12950	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HN014_12955	ENOG4105ID8	Transcriptional regulator, ARAC family
HN014_12970	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
HN014_12980	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HN014_12985	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HN014_13005	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HN014_13020	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HN014_13025	ENOG41065RQ	ADP-ribosylation crystallin J1
HN014_13030	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
HN014_13045	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HN014_13090	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HN014_13105	ENOG4105IUR	peptidase C10
HN014_13110	ENOG4108HRK	Histidine kinase
HN014_13115	ENOG4108NEV	two component transcriptional regulator, LytTR family
HN014_13180	ENOG4107SCK	Monooxygenase
HN014_13215	ENOG4108RCM	Nitroreductase
HN014_13220	ENOG4105KVH	Transcriptional regulator
HN014_13245	ENOG4105FQP	Beta-lactamase
HN014_13325	ENOG4105T16	Transcriptional regulator (AraC family)
HN014_13335	ENOG4105KNA	-acetyltransferase
HN014_13380	ENOG4105DY9	regulatoR
HN014_13395	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
HN014_13400	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HN014_13430	ENOG4105D5P	Methylmalonyl-coA mutase
HN014_13440	ENOG4105C2F	Histidine kinase
HN014_13445	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HN014_13465	ENOG4105BZG	amino acid carrier protein
HN014_13475	ENOG4108AEY	RNA polymerase sigma factor
HN014_13525	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HN014_13535	ENOG4105CWG	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 (By similarity)
HN014_13540	ENOG4105ECP	epimerase
HN014_13550	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HN014_13555	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HN014_13560	ENOG4108IUX	(ABC) transporter
HN014_13570	ENOG4105EGS	Mechanosensitive ion channel
HN014_13590	ENOG4105CSR	polyphosphate kinase 2
HN014_13600	ENOG4105FFC	UPF0187 protein
HN014_13640	ENOG4105K6V	RNA polymerase
HN014_13685	ENOG4107QI1	Mate efflux family protein
HN014_13720	ENOG4105DJT	lAO AO transport system ATPase
HN014_13725	ENOG4108ZHJ	Organic hydroperoxide resistance protein
HN014_13770	ENOG4105MHQ	Low-potential electron donor to a number of redox enzymes (By similarity)
HN014_13785	ENOG4105EMN	RNA polymerase sigma factor
HN014_13795	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HN014_13815	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HN014_13820	ENOG4107R51	Glycosyl transferase, family 2
HN014_13825	ENOG4105C7S	Dehydrogenase
HN014_13830	ENOG4107RBD	ABC, transporter
HN014_13835	ENOG4107RPQ	ABC transporter
HN014_13840	ENOG4105DIK	(ABC) transporter
HN014_13845	ENOG4105DSE	periplasmic solute binding protein
HN014_13850	ENOG4107RPQ	ABC transporter
HN014_13860	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
HN014_13870	ENOG4105CEV	competence damage-inducible protein
HN014_13875	ENOG4105KDC	50s ribosomal protein l28
HN014_13880	ENOG41083ND	50S ribosomal protein L33
HN014_13890	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HN014_13895	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HN014_13900	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
HN014_13930	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HN014_13945	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HN014_13950	ENOG4105CDU	Replicative dna helicase
HN014_13970	ENOG4105CI2	imidazolone-5-propionate hydrolase
HN014_13985	ENOG4105CIN	aminoacyl-histidine dipeptidase
HN014_14000	ENOG4107XH4	PPIases accelerate the folding of proteins (By similarity)
HN014_14010	ENOG4105SFS	phosphoesterase RecJ domain protein
HN014_14015	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HN014_14045	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HN014_14055	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
HN014_14065	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HN014_14095	ENOG4105C3F	Signal peptidase i
HN014_14100	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HN014_14110	ENOG4105FA0	parb-like partition protein
HN014_14115	ENOG4107QJE	Chromosome Partitioning Protein
HN014_14120	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
HN014_14125	ENOG4105D5P	Methylmalonyl-coA mutase
HN014_14145	ENOG4105DBI	uridine monophosphokinase
HN014_14185	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HN014_14190	ENOG4105D05	Receptor
HN014_14195	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HN014_14255	ENOG4105D05	Receptor
HN014_14270	ENOG4108AHD	Transcriptional regulator
HN014_14275	ENOG4105EN6	Membrane
HN014_14280	ENOG4105C3M	thioredoxin reductase
HN014_14360	ENOG4105KAF	membrAne
HN014_14425	ENOG4105C5Q	Transcriptional regulator
HN014_14440	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HN014_14505	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HN014_14540	ENOG4105NIV	Esterase
HN014_14570	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HN014_14590	ENOG4105FQP	Beta-lactamase
HN014_14605	ENOG4105EYW	Ion transport protein
HN014_14610	ENOG4105EUB	pirin domain protein
HN014_14645	ENOG4108XW0	May be a transcriptional activator of genes involved in the multiple antibiotic resistance (Mar) phenotype. It can also activate genes such as sodA, zwf and micF
HN014_14650	ENOG4108MUX	N-hydroxyarylamine O-acetyltransferase
HN014_14680	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HN014_14695	ENOG41066YJ	Beta-lactamase
HN014_14715	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HN014_14775	ENOG4108NEV	two component transcriptional regulator, LytTR family
HN014_14780	ENOG4108HRK	Histidine kinase
HN014_14785	ENOG4108IUW	ABC transporter
HN014_14840	ENOG4105CKI	cobalamin synthesis protein
HN014_14845	ENOG41068WN	
HN014_14870	ENOG4108W0I	acetyltransferase
HN014_14905	ENOG4105N14	lysine exporter protein LysE YggA
HN014_14920	ENOG4105CJ1	ABC, transporter
HN014_14925	ENOG4105VMP	Transcriptional regulator
HN014_15085	ENOG4106A4F	Removes the N-terminal methionine from nascent proteins (By similarity)
HN014_15195	ENOG4105CHP	RNA polymerase
HN014_15235	ENOG4105FQP	Beta-lactamase
HN014_15240	ENOG4105ECQ	AraC Family Transcriptional Regulator
HN014_15310	ENOG4105CHR	reductase
HN014_15335	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HN014_15365	ENOG4105BZU	Histidine kinase
HN014_15375	ENOG4105EUB	pirin domain protein
HN014_15415	ENOG4105C27	TonB-dependent Receptor Plug
HN014_15435	ENOG4105C1G	acyl-Coa dehydrogenase
HN014_15440	ENOG4105CHU	acetyl-coa acetyltransferase
HN014_15450	ENOG4105FS7	Transcriptional regulator
HN014_15455	ENOG4108IQE	Amp-dependent synthetase and ligase
HN014_15460	ENOG4108ETH	Formylglycinamide ribotide synthetase
HN014_15500	ENOG4105BZ1	(ABC) transporter
HN014_15510	ENOG4105CKK	Glycosyl transferase, family 2
HN014_15520	ENOG41081WG	50s ribosomal protein l31
HN014_15530	ENOG4105DEF	Extracellular solute-binding protein, family 5
HN014_15535	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HN014_15565	ENOG4105VG0	50S ribosomal protein l34
HN014_15570	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HN014_15595	ENOG4105CGY	Dna recombination protein
HN014_15605	ENOG4105E0A	ABC, transporter
HN014_15610	ENOG4105EHG	Permease protein
HN014_15625	ENOG4108UHF	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
HN014_15635	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HN014_15640	ENOG4108YZT	Adenosylcobinamide kinase
HN014_15660	ENOG4105EMN	RNA polymerase sigma factor
HN014_15680	ENOG4107QTF	adenylosuccinate lyase
HN014_15690	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HN014_15705	ENOG4105BZU	Histidine kinase
HN014_15725	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HN014_15730	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
HN014_15740	ENOG4105C1J	atp-dependent rna helicase
HN014_15755	ENOG4105E1F	short-chain dehydrogenase reductase
HN014_15760	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HN014_15770	ENOG4105C5H	ABC transporter
HN014_15800	ENOG4105C6K	Malic enzyme
HN014_15805	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
HN014_15865	ENOG4108K8S	endonuclease I
HN014_15895	ENOG4105CBC	glutamate synthase
HN014_15925	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HN014_15930	ENOG4105CDV	Ompa motb domain protein
HN014_15955	ENOG4105E1F	short-chain dehydrogenase reductase
HN014_15960	ENOG4105C28	cystathionine
HN014_15965	ENOG4108XM1	transcriptional regulator AsnC family
HN014_15970	ENOG4105C9Q	fumarate hydratase class II
HN014_15980	ENOG4107RNH	Outer membrane receptor FepA
HN014_15995	ENOG4105K89	arsenate reductase
HN014_16015	ENOG4105KWI	UPF0339 protein
HN014_16020	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HN014_16025	ENOG41080WS	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HN014_16040	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HN014_16115	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HN014_16130	ENOG4105CSM	endonuclease III
HN014_16135	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HN014_16205	ENOG4105CD3	dihydroorotase
HN014_16230	ENOG4105DZ0	fad dependent oxidoreductase
HN014_16235	ENOG4106N3A	copper homeostasis protein cutc
HN014_16265	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HN014_16275	ENOG4105EUJ	GTP cyclohydrolase i
HN014_16305	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HN014_16315	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
HN014_16330	ENOG4105C3G	gtp-binding protein
HN014_16340	ENOG4105BZU	Histidine kinase
HN014_16400	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
HN014_16410	ENOG4105DY9	regulatoR
HN014_16415	ENOG4108HRK	Histidine kinase
HN014_16435	ENOG4105KWG	Pfam:DUF1696
HN014_16470	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
HN014_16475	ENOG4105DF5	DNA topoisomerase IV, subunit A
HN014_16480	ENOG4105D64	Mechanosensitive ion channel
HN014_16495	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HN014_16500	ENOG4105EE5	Membrane protein terC
HN014_16520	ENOG4108VVK	transcriptional Regulator, AsnC
HN014_16525	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HN014_16620	ENOG4105C6T	cysteine synthase
HN014_16625	ENOG4105DZ2	Transcriptional regulator
HN014_16635	ENOG4105KA0	thioesterase Superfamily protein
HN014_16640	ENOG4105E4F	Isochorismate synthase
HN014_16645	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
HN014_16655	ENOG4105QNR	S1 RNA binding domain protein
HN014_16685	ENOG4105CPP	Dehydrogenase, E1 component
HN014_16695	ENOG4108URH	decarboxylase
HN014_16700	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HN014_16725	ENOG4105C8P	)-transporter
HN014_16735	ENOG4105D49	3-dehydroquinate synthase
HN014_16755	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
HN014_16790	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HN014_16795	ENOG4105DCI	Phosphohydrolase
HN014_16800	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HN014_16805	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HN014_16810	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HN014_16815	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HN014_16825	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HN014_16835	ENOG4105CHR	reductase
HN014_16855	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
HN014_16860	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HN014_16865	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HN014_16870	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HN014_16875	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HN014_16885	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HN014_16890	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HN014_16895	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HN014_16915	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HN014_16920	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HN014_16925	ENOG4105CXT	aspartate transcarbamylase
HN014_16940	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
HN014_16945	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HN014_16960	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
HN014_17025	ENOG4105DY9	regulatoR
HN014_17030	ENOG4105CPK	Glycosyl transferase (Group 1
HN014_17055	ENOG4105CQB	FAD linked oxidase domain protein
HN014_17070	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HN014_17075	ENOG4105CK2	sodium dicarboxylate symporter
HN014_17085	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
HN014_17095	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HN014_17110	ENOG4105D98	threonine synthase
HN014_17115	ENOG4107RDY	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
HN014_17120	ENOG4105CFH	Aspartokinase
HN014_17130	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HN014_17140	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HN014_17155	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HN014_17160	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HN014_17165	ENOG4107QR7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HN014_17175	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HN014_17180	ENOG4107QN2	dihydrolipoyl dehydrogenase
HN014_17190	ENOG4105E0X	reductase
HN014_17205	ENOG4105JAB	phenazine biosynthesis protein, phzf family
HN014_17220	ENOG4105DR4	Methyltransferase
HN014_17225	ENOG4105ER2	Ompa motb domain protein
HN014_17235	ENOG4105BZU	Histidine kinase
HN014_17255	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
HN014_17265	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HN014_17270	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HN014_17285	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HN014_17295	ENOG41082YX	Transcriptional regulator, arsr family
HN014_17305	ENOG4105N14	lysine exporter protein LysE YggA
HN014_17315	ENOG4108JPW	Aminotransferase
HN014_17375	ENOG4108NEV	two component transcriptional regulator, LytTR family
HN014_17395	ENOG4105DA5	(ABC) transporter
HN014_17400	ENOG4105C2F	Histidine kinase
HN014_17405	ENOG4108NEV	two component transcriptional regulator, LytTR family
HN014_17415	ENOG4108UY2	Chloramphenicol acetyltransferase
HN014_17435	ENOG4108NKJ	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HN014_17460	ENOG4105DXD	2-methylcitrate dehydratase
HN014_17475	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HN014_17485	ENOG4105C19	ABC transporter
HN014_17495	ENOG4107RBB	ABC transporter, permease
HN014_17555	ENOG4105C2F	Histidine kinase
HN014_17580	ENOG4107S1E	Beta-lactamase
HN014_17585	ENOG4105DY9	regulatoR
HN014_17590	ENOG4108HRK	Histidine kinase
HN014_17595	ENOG4105CWX	Alpha-1,2-mannosidase
HN014_17605	ENOG4105CKB	glycosidase
HN014_17620	ENOG4105CWX	Alpha-1,2-mannosidase
HN014_17630	ENOG4105E2D	ec 3.2.1.52
HN014_17710	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
HN014_17725	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
HN014_17765	ENOG4108JA2	transcriptioN-repair coupling factor
HN014_17780	ENOG4105EMU	Dehydrogenase
HN014_17815	ENOG4105K6H	D-cysteine desulfhydrase
HN014_17825	ENOG41082BM	Transcriptional regulator, arsr family
HN014_17830	ENOG4107TPS	domain protein
HN014_17835	ENOG4105C6X	Major Facilitator
HN014_17840	ENOG4107QI6	Cysteine desulfurase
HN014_17850	ENOG4107V40	secretion protein, HlyD family
HN014_17855	ENOG4108JJA	ABC, transporter
HN014_17875	ENOG4105BZU	Histidine kinase
HN014_17900	ENOG4105CYP	glycoside hydrolase, family
HN014_17920	ENOG4105FQP	Beta-lactamase
HN014_17930	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
HN014_18000	ENOG4105DY9	regulatoR
HN014_18025	ENOG4105C1J	atp-dependent rna helicase
HN014_18030	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
HN014_18035	ENOG4105CN1	protease
HN014_18050	ENOG4105DY9	regulatoR
HN014_18055	ENOG4105C2F	Histidine kinase
HN014_18090	ENOG4108SU4	UPF0309 protein
HN014_18160	ENOG4105HF0	Membrane
HN014_18165	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
HN014_18175	ENOG4108XM1	transcriptional regulator AsnC family
HN014_18215	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HN014_18220	ENOG4108ZG0	Ompa motb domain protein
HN014_18230	ENOG4105UYK	outer membrane protein a
HN014_18235	ENOG4105DEU	major facilitator superfamily
HN014_18240	ENOG4105ERG	peptidase m48, ste24p
HN014_18275	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
HN014_18280	ENOG4107SJ9	decarboxylase
HN014_18295	ENOG4105C5H	ABC transporter
HN014_18305	ENOG4107QX3	carboxylase
HN014_18315	ENOG4105CP2	von willebrand factor, type a
HN014_18420	ENOG4105H3G	oxidoreductase
HN014_18425	ENOG410904A	RNA polymerase
HN014_18470	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
HN014_18485	ENOG4105DTQ	mandelate racemase muconate lactonizing
HN014_18490	ENOG4107W2A	UPF0173 metal-dependent hydrolase
HN014_18495	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
HN014_18515	ENOG4105CUY	Mechanosensitive ion channel
HN014_18525	ENOG4105CTJ	Metal Dependent Phosphohydrolase
HN014_18530	ENOG4105CHU	acetyl-coa acetyltransferase
HN014_18535	ENOG4107SN7	NLP P60 protein
HN014_18550	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
HN014_18560	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HN014_18570	ENOG4105D7W	serine acetyltransferase
HN014_18575	ENOG4105C6T	cysteine synthase
HN014_18580	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HN014_18595	ENOG4108I7Y	domain protein
HN014_18615	ENOG4105CAT	Cytidine monophosphate kinase
HN014_18620	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HN014_18665	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HN014_18670	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
HN014_18680	ENOG4105MME	Sugar o-acyltransferase, sialic acid o-acetyltransferase neud family
HN014_18685	ENOG4105D3Q	Sugar transferase
HN014_18705	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HN014_18710	ENOG4105D3Q	Sugar transferase
HN014_18725	ENOG4107TYR	Glycosyl Transferase
HN014_18735	ENOG4105CAQ	asparagine synthetase
HN014_18755	ENOG4105CPK	Glycosyl transferase (Group 1
HN014_18775	ENOG4107QQG	Dehydrogenase
HN014_18780	ENOG4108IAJ	Nad-dependent epimerase dehydratase
HN014_18785	ENOG4105CPP	Dehydrogenase, E1 component
HN014_18825	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
HN014_18830	ENOG4105C98	muts2 protein
HN014_18835	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
HN014_18840	ENOG4108RG0	uracil-dna glycosylase
HN014_18860	ENOG4107RJ1	sodium solute
HN014_18865	ENOG4105EE0	oxidoreductase
HN014_18875	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
HN014_18885	ENOG4105CHR	reductase
HN014_18895	ENOG4107RSM	transcriptional regulator
HN014_18900	ENOG4105C84	Histidine ammonia-lyase
HN014_18910	ENOG4105CGP	Urocanate hydratase
HN014_18915	ENOG41088SP	formiminoglutamate hydrolase
HN014_18940	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HN014_18960	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HN014_18965	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HN014_18970	ENOG4105K70	DNA-binding protein
HN014_18975	ENOG4108UJU	UPF0301 protein
HN014_18980	ENOG4105F0I	Aminotransferase
HN014_19065	ENOG4105EB3	Histidine kinase
HN014_19070	ENOG4105DY9	regulatoR
HN014_19090	ENOG4105CVK	Glutamate decarboxylase
HN014_19125	ENOG4108NEV	two component transcriptional regulator, LytTR family
HN014_19130	ENOG4108HRK	Histidine kinase
HN014_19135	ENOG4108HRK	Histidine kinase
HN014_19145	ENOG4105E46	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process
HN014_19190	ENOG4105FTV	AraC Family Transcriptional Regulator
HN014_19200	ENOG4108XG2	Histidine kinase
HN014_19210	ENOG4105CUT	histidyl-tRNA synthetase
HN014_19215	ENOG4107RBB	ABC transporter, permease
HN014_19225	ENOG4108KPZ	tonB-dependent Receptor
HN014_19230	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HN014_19235	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HN014_19240	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
HN014_19245	ENOG4108NEV	two component transcriptional regulator, LytTR family
HN014_19250	ENOG4105C25	Primosomal protein n'
HN014_19275	ENOG4107U9T	Pfam:Ribonuclease_BN
HN014_19280	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HN014_19285	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HN014_19295	ENOG4108Z03	MAF-like protein
HN014_19305	ENOG4105KZX	Pterin carbinolamine dehydratase
HN014_19310	ENOG4105CDY	transcriptional regulatory protein
HN014_19325	ENOG4105C26	Dehydrogenase
HN014_19340	ENOG4105CEY	Amp-dependent synthetase and ligase
HN014_19370	ENOG4107RJC	Iron-containing alcohol dehydrogenase
HN014_19380	ENOG4105C7H	Helicase, RecD TraA family
HN014_19420	ENOG4105D17	glycoside hydrolase, family 3 domain protein
HN014_19430	ENOG4105DF6	Fe-S oxidoreductase
HN014_19440	ENOG4105DF6	Fe-S oxidoreductase
HN014_19445	ENOG4107PE3	Mammalian cell entry related domain protein
HN014_19450	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HN014_19470	ENOG4105CH6	catalase
HN014_19490	ENOG4105CTQ	phosphohexokinase
HN014_19500	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HN014_19510	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HN014_19590	ENOG4105EFZ	amidohydrolase
HN014_19600	ENOG4105CH2	amidohydrolase
HN014_19630	ENOG4105EUJ	GTP cyclohydrolase i
HN014_19635	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HN014_19720	ENOG4105K6H	D-cysteine desulfhydrase
HN014_19735	ENOG4108V06	Glutathione peroxidase
HN014_19790	ENOG4105DJ4	phosphatidylserine decarboxylase
HN014_19815	ENOG4108IYU	L-aspartate oxidase
HN014_19820	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HN014_19825	ENOG4105CD5	CoA-binding domain protein
HN014_19830	ENOG4105CFP	Peptidase U32
HN014_19850	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HN014_19855	ENOG4107QZB	decarboxylase
HN014_19885	ENOG4107SRH	Nad-dependent epimerase dehydratase
HN014_19890	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HN014_19895	ENOG4105DAT	cobalamin (vitamin b12) biosynthesis cbix protein
HN014_19900	ENOG4105CTK	cobaltochelatase, cobn subunit
HN014_19905	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HN014_19910	ENOG4105EET	magnesium chelatase
HN014_19960	ENOG4105DUU	IucA IucC family protein
HN014_19965	ENOG4105DUU	IucA IucC family protein
HN014_20005	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HN014_20020	ENOG4105DAV	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HN014_20040	ENOG4105EWK	phytoene
HN014_20075	ENOG4108HRK	Histidine kinase
HN014_20090	ENOG4105DY9	regulatoR
HN014_20110	ENOG4105KNA	-acetyltransferase
HN014_20115	ENOG4105KVH	Transcriptional regulator
HN014_20125	ENOG4105DY9	regulatoR
HN014_20150	ENOG4108XM1	transcriptional regulator AsnC family
HN014_20155	ENOG4107RCH	Diaminopropionate ammonia-lyase
HN014_20160	ENOG4105N14	lysine exporter protein LysE YggA
HN014_20195	ENOG4107UA7	cobalamin biosynthesis protein CbiD
HN014_20205	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
HN014_20220	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
HN014_20225	ENOG4105E4R	Precorrin-3B C17-methyltransferase
HN014_20235	ENOG4108WBT	adenosyltransferase
HN014_20240	ENOG4107QRP	cobalamin biosynthesis protein CobW
HN014_20250	ENOG4108UB4	uncharacterized protein ygjQ
HN014_20255	ENOG4105CRE	cytochrome C
HN014_20270	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HN014_20280	ENOG4105DFD	Na H antiporter
HN014_20290	ENOG4108RCM	Nitroreductase
HN014_20295	ENOG4105MH8	Thioredoxin disulfide isomerase
HN014_20300	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
HN014_20305	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HN014_20320	ENOG4105CNU	cell division protein FtsK
HN014_20325	ENOG41080IJ	Diacylglycerol kinase
HN014_20330	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HN014_20345	ENOG4105D3R	alkyl hydroperoxide reductase
HN014_20355	ENOG4105C28	cystathionine
HN014_20360	ENOG4105FJR	Lmbe family
HN014_20375	ENOG4105IIU	Aminopeptidase
HN014_20420	ENOG4108QBX	(LipO)protein
HN014_20440	ENOG4105BZU	Histidine kinase
HN014_20445	ENOG4105BZU	Histidine kinase
HN014_20460	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HN014_20465	ENOG4105C1J	atp-dependent rna helicase
HN014_20495	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HN014_20510	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
HN014_20530	ENOG4105D5D	udp-galactopyranose mutase
HN014_20535	ENOG4105GH9	galactofuranosyltransferase
HN014_20540	ENOG4105DR5	peptidase
HN014_20550	ENOG4107QI6	Cysteine desulfurase
HN014_20590	ENOG4105C8Y	Acetylornithine aminotransferase
HN014_20665	ENOG4105CN9	Peptidase m42 family protein
HN014_20670	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HN014_20675	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HN014_20680	ENOG4105BZU	Histidine kinase
HN014_20690	ENOG4107QN1	sodium solute
HN014_20715	ENOG4108RMU	ferritin dps family protein
HN014_20745	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HN014_20760	ENOG4107QKV	phosphomannomutase
HN014_20775	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HN014_20795	ENOG4105CFG	Acts as a chaperone (By similarity)
HN014_20800	ENOG4105EJQ	L-serine dehydratase
HN014_20815	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HN014_20820	ENOG4105DR9	pseudouridine synthase
HN014_20850	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HN014_20855	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HN014_20860	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HN014_20865	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HN014_20870	ENOG4105M08	Membrane
HN014_20890	ENOG41077ZI	
HN014_20900	ENOG4105K5B	UPF0225 protein
HN014_20930	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HN014_20935	ENOG4108VYJ	response regulator receiver protein
HN014_20940	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HN014_20950	ENOG4105PV1	biotin lipoyl attachment domaiN-containing protein
HN014_20955	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HN014_20960	ENOG4107QX3	carboxylase
HN014_20970	ENOG4105CH7	arginosuccinase
HN014_20980	ENOG4107T6X	nag kinase
HN014_20990	ENOG4105C8Y	Acetylornithine aminotransferase
HN014_21000	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HN014_21005	ENOG4105CDH	Citrulline--aspartate ligase
HN014_21020	ENOG4105C7B	Threonine dehydratase
HN014_21025	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HN014_21035	ENOG4105C7K	acetolactate synthase
HN014_21040	ENOG4105C01	Dihydroxy-acid dehydratase
HN014_21045	ENOG4105WH1	Two component transcriptional regulator luxr family
HN014_21050	ENOG4105BZU	Histidine kinase
HN014_21070	ENOG4105P4J	Allophanate hydrolase, subunit 1
HN014_21075	ENOG4105E7W	lamb ycsf family protein
HN014_21090	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
HN014_21150	ENOG4105CS6	Rhs element vgr protein
HN014_21280	ENOG4107QWK	SAICAR synthetase
HN014_21285	ENOG4105C9A	Phoh family
HN014_21310	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HN014_21345	ENOG4108YZA	Nitrogen regulatory protein pii
HN014_21355	ENOG4105BZU	Histidine kinase
HN014_21360	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
HN014_21370	ENOG4105C4X	radical SAM domain protein
HN014_21410	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HN014_21425	ENOG4105C0P	Mg chelatase subunit ChlI
HN014_21430	ENOG4105CFH	Aspartokinase
HN014_21445	ENOG4105C9K	Endothelin-converting enzyme 1
HN014_21470	ENOG4105BZU	Histidine kinase
HN014_21495	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HN014_21500	ENOG4105CTQ	phosphohexokinase
HN014_21505	ENOG4108JJA	ABC, transporter
HN014_21520	ENOG4105BZU	Histidine kinase
HN014_21540	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HN014_21555	ENOG4108YYH	Nadph-dependent fmn reductase
HN014_21560	ENOG4105CKI	cobalamin synthesis protein
HN014_21580	ENOG4105C1J	atp-dependent rna helicase
HN014_21585	ENOG4105S2T	inner membrane protein YbcI
HN014_21590	ENOG4105BZ1	(ABC) transporter
HN014_21615	ENOG4105ECQ	AraC Family Transcriptional Regulator
HN014_21620	ENOG4107RAN	Peptidase, M16
HN014_21660	ENOG4105CD8	aminopeptidase N
HN014_21675	ENOG4108YXU	transcriptional regulator AsnC family
HN014_21690	ENOG4108NEV	two component transcriptional regulator, LytTR family
HN014_21695	ENOG4107QN2	dihydrolipoyl dehydrogenase
HN014_21715	ENOG4105DY9	regulatoR
HN014_21720	ENOG4108HRK	Histidine kinase
HN014_21730	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HN014_21765	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HN014_21775	ENOG4107XI7	Tetr family transcriptional regulator
HN014_21805	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HN014_21810	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HN014_21815	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
HN014_21820	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HN014_21835	ENOG4105DFA	alanine racemase domain protein
HN014_21840	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
HN014_21845	ENOG4105EYW	Ion transport protein
HN014_21850	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HN014_21880	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HN014_21935	ENOG4105CN1	protease
HN014_22015	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HN014_22020	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HN014_22050	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HN014_22065	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HN014_22070	ENOG4108URH	decarboxylase
HN014_22075	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HN014_22080	ENOG4108MJ3	acetyltransferase
HN014_22090	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HN014_22105	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
HN014_22145	ENOG4107QJE	Chromosome Partitioning Protein
HN014_22195	ENOG4107XMK	single-stranded DNA-binding protein
HN014_22300	ENOG4107QJE	Chromosome Partitioning Protein
HN014_22315	ENOG4105D5G	Transposase
HN014_22360	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HN014_22545	ENOG4105W5Q	DNA repair protein (RadC