locus-tag	class	description
HC341_00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
HC341_00010	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
HC341_00015	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
HC341_00020	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HC341_00030	ENOG4108ZI0	d,d-heptose 1,7-bisphosphate phosphatase
HC341_00035	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
HC341_00040	ENOG4107QIB	glycyl-tRNA synthetase, alpha subunit
HC341_00045	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HC341_00050	ENOG4105VFE	sira family
HC341_00055	ENOG4105C5F	glutamine synthetase
HC341_00065	ENOG4105CUX	Signal transduction histidine kinase
HC341_00070	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HC341_00075	ENOG4105CHR	reductase
HC341_00080	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
HC341_00085	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
HC341_00090	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
HC341_00095	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HC341_00100	ENOG41063SB	peptidase
HC341_00105	ENOG4105CN1	protease
HC341_00115	ENOG4105E14	MotA TolQ exbB proton channel
HC341_00120	ENOG4106VK6	Flagellar motor protein
HC341_00125	ENOG4105VNG	YcgL domain-containing protein
HC341_00135	ENOG4105C29	acyl-CoA thioesterase
HC341_00140	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
HC341_00150	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
HC341_00160	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
HC341_00165	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
HC341_00170	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HC341_00180	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
HC341_00185	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
HC341_00200	ENOG4105CH7	arginosuccinase
HC341_00210	ENOG4108NEV	two component transcriptional regulator, LytTR family
HC341_00215	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
HC341_00220	ENOG41076E6	Uroporphyrinogen-III Synthase
HC341_00225	ENOG4105ECF	c-methyltransferase
HC341_00235	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
HC341_00240	ENOG4105C6K	Malic enzyme
HC341_00245	ENOG4105EV9	Alpha Beta Hydrolase
HC341_00250	ENOG4105C7I	Dehydrogenase
HC341_00265	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HC341_00270	ENOG4107QN2	dihydrolipoyl dehydrogenase
HC341_00275	ENOG4107QSN	dihydrolipoamide acetyltransferase
HC341_00280	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
HC341_00310	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HC341_00320	ENOG4108RPN	Protein smg homolog
HC341_00325	ENOG4105C79	DNA protecting protein DprA
HC341_00335	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
HC341_00340	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
HC341_00345	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HC341_00355	ENOG4105ES5	Histidine kinase
HC341_00360	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HC341_00365	ENOG4105C1A	potassium transporter peripheral membrane
HC341_00370	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
HC341_00390	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
HC341_00395	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
HC341_00400	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
HC341_00405	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
HC341_00410	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
HC341_00415	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
HC341_00420	ENOG4105KPZ	phosphoribosyl-atp pyrophosphatase
HC341_00425	ENOG4105WKS	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
HC341_00430	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
HC341_00435	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
HC341_00445	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
HC341_00450	ENOG4105C7S	Dehydrogenase
HC341_00465	ENOG4105CR4	methylisocitrate lyase
HC341_00470	ENOG4105BZN	citrate synthase
HC341_00475	ENOG4108I0Z	Aconitate hydratase
HC341_00480	ENOG4105C7F	AcnD-accessory protein PrpF
HC341_00485	ENOG4105DXD	2-methylcitrate dehydratase
HC341_00490	ENOG4108Z9K	Osmotically inducible protein
HC341_00495	ENOG4105MYT	Heat shock protein
HC341_00500	ENOG4105MYT	Heat shock protein
HC341_00515	ENOG4105CZ6	Can catalyze the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine (By similarity)
HC341_00520	ENOG4105C26	Dehydrogenase
HC341_00525	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
HC341_00535	ENOG4108YZT	Adenosylcobinamide kinase
HC341_00540	ENOG4105GN9	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
HC341_00550	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
HC341_00555	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HC341_00560	ENOG4105EFT	decarboxylase
HC341_00565	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
HC341_00585	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
HC341_00590	ENOG4105EHG	Permease protein
HC341_00595	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
HC341_00600	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HC341_00605	ENOG41068B1	Cob-I-yrinic acid a,c-diamide adenosyltransferase
HC341_00610	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
HC341_00620	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HC341_00630	ENOG4105C8Q	Methyl-accepting chemotaxis
HC341_00635	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
HC341_00640	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HC341_00655	ENOG4105C75	arginyL-tRNA synthetase
HC341_00670	ENOG4105C25	Primosomal protein n'
HC341_00675	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HC341_00680	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HC341_00685	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
HC341_00695	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
HC341_00700	ENOG4105C2M	dna polymerase I
HC341_00715	ENOG4105FE1	phytoene synthase
HC341_00720	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HC341_00725	ENOG4105BZU	Histidine kinase
HC341_00730	ENOG4108EX3	reductase
HC341_00735	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
HC341_00755	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
HC341_00800	ENOG41067D0	Antitoxin component of a toxin-antitoxin (TA) module. Upon expression in M.smegmatis neutralizes the effect of toxin RelE2
HC341_00815	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
HC341_00820	ENOG4107QTH	restriction modification system DNA specificity domain
HC341_00825	ENOG4105CB5	ATP-dependent DNA helicase recG
HC341_00835	ENOG4107R3N	Filamentation induced by cAMP protein fic
HC341_00870	ENOG4105CGK	Exodeoxyribonuclease III
HC341_00875	ENOG4105K59	histidine triad (HIT) protein
HC341_00880	ENOG4105DGW	oligopeptidase A
HC341_00905	ENOG4108Z0R	Transferase
HC341_00955	ENOG4108R86	Transcriptional regulator
HC341_00975	ENOG4105E2X	shikimate dehydrogenase
HC341_00980	ENOG4105D52	delta-aminolevulinic acid dehydratase
HC341_00985	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HC341_00990	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HC341_00995	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
HC341_01000	ENOG4105BZ8	glutamate synthase
HC341_01005	ENOG4105CBC	glutamate synthase
HC341_01015	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
HC341_01020	ENOG4105D49	3-dehydroquinate synthase
HC341_01025	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HC341_01030	ENOG4105E4G	Type IV pilus
HC341_01055	ENOG4108JQC	penicillin-binding protein 1A
HC341_01065	ENOG4105BZN	citrate synthase
HC341_01070	ENOG4105VFB	Binds the 23S rRNA (By similarity)
HC341_01085	ENOG4105CQB	FAD linked oxidase domain protein
HC341_01090	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HC341_01105	ENOG4105CSA	Coproporphyrinogen iii oxidase
HC341_01110	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
HC341_01115	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
HC341_01120	ENOG4105DSJ	YicC domain protein
HC341_01125	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
HC341_01130	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
HC341_01135	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HC341_01145	ENOG4105KME	endoribonuclease L-psp
HC341_01150	ENOG4105CB5	ATP-dependent DNA helicase recG
HC341_01155	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
HC341_01160	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
HC341_01165	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
HC341_01185	ENOG4105D7T	ABC transporter
HC341_01190	ENOG4108IFG	nitrite reductase, (NAD(P)H)
HC341_01205	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HC341_01290	ENOG4105D0M	Protease HtpX homolog
HC341_01300	ENOG4108R85	Short chain dehydrogenase
HC341_01325	ENOG4105C1J	atp-dependent rna helicase
HC341_01335	ENOG41061WM	D-Alanyl-D-Alanine
HC341_01355	ENOG4105E66	phosphoriboisomerase A
HC341_01360	ENOG4105C7B	Threonine dehydratase
HC341_01365	ENOG4105BZM	domain protein
HC341_01380	ENOG4108594	Permease of the drug metabolite transporter
HC341_01390	ENOG4105DR5	peptidase
HC341_01405	ENOG4105W8B	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division (By similarity)
HC341_01420	ENOG4107RAQ	aminopeptidase
HC341_01425	ENOG4105D0A	hydroxylase
HC341_01430	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HC341_01480	ENOG4105C0Z	ABC transporter
HC341_01485	ENOG4105EQN	UPF0261 protein
HC341_01500	ENOG4107S78	Band 7 protein
HC341_01505	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HC341_01510	ENOG4105C26	Dehydrogenase
HC341_01515	ENOG4107QKW	extracellular solute-binding protein family 1
HC341_01520	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
HC341_01525	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HC341_01530	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
HC341_01535	ENOG4107QK8	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HC341_01540	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
HC341_01545	ENOG4107T4Z	adenosine kinase
HC341_01550	ENOG4105CSU	acyl-Coa dehydrogenase
HC341_01555	ENOG4105CHM	Aminotransferase
HC341_01565	ENOG4105ES9	amino acid
HC341_01570	ENOG4105C32	Amino acid ABC transporter (Permease)
HC341_01580	ENOG4105C0Z	ABC transporter
HC341_01585	ENOG4108IV0	ABC, transporter
HC341_01595	ENOG4105E4C	Lytic transglycosylase catalytic
HC341_01605	ENOG4108WBT	adenosyltransferase
HC341_01615	ENOG4107T0X	DNA ligase
HC341_01630	ENOG4107QRT	dEAD DEAH box helicase
HC341_01645	ENOG4105DZ2	Transcriptional regulator
HC341_01655	ENOG4105DFT	pur operon repressor
HC341_01660	ENOG4105CH5	extracellular solute-binding protein, family 7
HC341_01665	ENOG4105XDZ	Tripartite ATP-independent periplasmic transporter
HC341_01670	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HC341_01675	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HC341_01690	ENOG41067MG	lrgb family
HC341_01705	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
HC341_01710	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
HC341_01720	ENOG4108UQY	Iron-storage protein
HC341_01725	ENOG4108YXA	Membrane
HC341_01735	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
HC341_01740	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
HC341_01745	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
HC341_01750	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
HC341_01780	ENOG4105DFM	M18 family aminopeptidase
HC341_01785	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
HC341_01790	ENOG4108194	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
HC341_01805	ENOG4108RAV	Conserved protein
HC341_01810	ENOG4107VXM	glycerophosphoryl diester phosphodiesterase
HC341_01820	ENOG4105EM7	Selenocysteine-specific translation elongation factor
HC341_01855	ENOG4105CHH	sulfate transporter
HC341_01875	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HC341_01890	ENOG4105EYU	Glutamine amido-transferase
HC341_01895	ENOG4105M90	Glutamate synthase alpha subunit domain protein
HC341_01900	ENOG4105CBC	glutamate synthase
HC341_01935	ENOG4107TE5	Lipid kinase
HC341_01950	ENOG4105DJ9	glucan biosynthesis protein
HC341_01955	ENOG4105C3A	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) (By similarity)
HC341_01965	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HC341_01970	ENOG4107QK5	Homocysteine s-methyltransferase
HC341_01980	ENOG4105XEA	Tetr family transcriptional regulator
HC341_01985	ENOG4105C94	Transporter
HC341_02000	ENOG4105DHF	Membrane
HC341_02005	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
HC341_02030	ENOG4105EJC	lysr family transcriptional regulator
HC341_02035	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HC341_02040	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
HC341_02065	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HC341_02095	ENOG4105KK6	nuclease
HC341_02100	ENOG4108F3G	Type I restriction-modification system, R subunit
HC341_02135	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
HC341_02140	ENOG4108RAV	Conserved protein
HC341_02195	ENOG4108KU3	Integrase
HC341_02205	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
HC341_02210	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
HC341_02220	ENOG4105KCK	Peptidoglycan-associated lipoprotein
HC341_02225	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
HC341_02235	ENOG4105M8F	Biopolymer transport protein exbD tolR
HC341_02240	ENOG4105E02	MotA TolQ exbB proton channel
HC341_02245	ENOG4107YD3	Thioesterase
HC341_02250	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HC341_02260	ENOG4107WP9	Histidine kinase
HC341_02265	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
HC341_02270	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
HC341_02275	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
HC341_02280	ENOG4105CDY	transcriptional regulatory protein
HC341_02290	ENOG4105C0Z	ABC transporter
HC341_02295	ENOG4108IV0	ABC, transporter
HC341_02300	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HC341_02320	ENOG4105CEY	Amp-dependent synthetase and ligase
HC341_02335	ENOG4105CHU	acetyl-coa acetyltransferase
HC341_02345	ENOG4105CHR	reductase
HC341_02360	ENOG4105ERG	peptidase m48, ste24p
HC341_02370	ENOG4105RH4	Glycine cleavage system transcriptional repressor
HC341_02375	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
HC341_02380	ENOG4105GJM	(LipO)protein
HC341_02385	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
HC341_02390	ENOG4105CEY	Amp-dependent synthetase and ligase
HC341_02405	ENOG4105C01	Dihydroxy-acid dehydratase
HC341_02410	ENOG4105D6Z	AFG1 family ATPase
HC341_02435	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HC341_02440	ENOG4105DWV	Homoserine O-trans-acetylase
HC341_02445	ENOG4108VIA	integral membrane protein
HC341_02450	ENOG4105II7	pyrroline-5-carboxylate reductase
HC341_02455	ENOG4105DFA	alanine racemase domain protein
HC341_02460	ENOG4105CZX	twitching motility protein
HC341_02465	ENOG4105CZX	twitching motility protein
HC341_02490	ENOG4107QPN	acyl-Coa dehydrogenase
HC341_02505	ENOG4105CD3	dihydroorotase
HC341_02510	ENOG4105CXT	aspartate transcarbamylase
HC341_02515	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
HC341_02520	ENOG4107Y66	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
HC341_02525	ENOG4108UJU	UPF0301 protein
HC341_02540	ENOG4105D7Z	glutathione synthase
HC341_02545	ENOG4108UNF	response regulator
HC341_02550	ENOG4105M3Z	response regulator
HC341_02555	ENOG4108ZGA	chew protein
HC341_02560	ENOG4105C8Q	Methyl-accepting chemotaxis
HC341_02565	ENOG4105BZU	Histidine kinase
HC341_02575	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HC341_02585	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
HC341_02590	ENOG4105SYT	Methylenetetrahydrofolate reductase
HC341_02595	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
HC341_02600	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
HC341_02615	ENOG4105CV1	Transketolase (EC 2.2.1.1)
HC341_02620	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HC341_02625	ENOG4105BZA	Phosphoglycerate kinase
HC341_02630	ENOG4105C8V	SAICAR synthetase
HC341_02675	ENOG4105BZS	acriflavin resistance protein
HC341_02685	ENOG4108IQE	Amp-dependent synthetase and ligase
HC341_02690	ENOG4105EMU	Dehydrogenase
HC341_02695	ENOG4108RWI	nicotinamidase
HC341_02705	ENOG4107QYD	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
HC341_02760	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
HC341_02780	ENOG4105DG7	nitrate ABC transporter
HC341_02795	ENOG4105EIG	urea carboxylase-associated protein 1
HC341_02800	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HC341_02825	ENOG4105CYM	Glutathione S-transferase
HC341_02845	ENOG4105I9P	Metallothiol transferase which confers resistance to fosfomycin by catalyzing the addition of a thiol cofactor to fosfomycin. L-cysteine is probably the physiological thiol donor (By similarity)
HC341_02860	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
HC341_02865	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
HC341_02870	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
HC341_02875	ENOG4105HBR	Rna-binding protein
HC341_02885	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
HC341_02890	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HC341_02895	ENOG4105EEI	dihydropteroate synthase
HC341_02900	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
HC341_02905	ENOG4105CP7	Triose-phosphate isomerase
HC341_02910	ENOG4107EJC	Preprotein translocase subunit SecG
HC341_02920	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HC341_02925	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HC341_02930	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
HC341_02935	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HC341_02945	ENOG4107QIZ	NADH dehydrogenase
HC341_02950	ENOG4108IEH	NADH dehydrogenase subunit g
HC341_02950	ENOG4108IEH	NADH dehydrogenase subunit g
HC341_02955	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
HC341_02960	ENOG41081XG	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HC341_02965	ENOG4105DF2	NADH dehydrogenase subunit j
HC341_02970	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HC341_02980	ENOG4105C8S	subunit m
HC341_02985	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HC341_03010	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
HC341_03045	ENOG4105C09	Bile acid
HC341_03055	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HC341_03060	ENOG4105CHU	acetyl-coa acetyltransferase
HC341_03065	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HC341_03090	ENOG4105IFJ	Histidine kinase
HC341_03095	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
HC341_03115	ENOG4105DS1	cytochrome b561
HC341_03120	ENOG4108YYC	ycei family
HC341_03125	ENOG4105E3A	(ABC) transporter
HC341_03130	ENOG4105DA5	(ABC) transporter
HC341_03135	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
HC341_03145	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
HC341_03170	ENOG4105BZU	Histidine kinase
HC341_03175	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
HC341_03180	ENOG4105CQ7	ATP-dependent helicase
HC341_03205	ENOG4105C5H	ABC transporter
HC341_03210	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HC341_03215	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HC341_03220	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
HC341_03225	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
HC341_03230	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
HC341_03240	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
HC341_03250	ENOG4107YIM	Involved in the transcription termination process (By similarity)
HC341_03255	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
HC341_03260	ENOG4108ZAI	phosphatidylglycerophosphatase a
HC341_03270	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
HC341_03300	ENOG4106BRA	Membrane
HC341_03310	ENOG4105CC5	ABC transporter
HC341_03315	ENOG4105DIK	(ABC) transporter
HC341_03320	ENOG4105DSE	periplasmic solute binding protein
HC341_03340	ENOG4105D0S	secretion protein (HlyD
HC341_03355	ENOG4108UVJ	appr-1-p processing domain protein
HC341_03375	ENOG4105CJW	magnesium transporter
HC341_03385	ENOG4107Z3H	Transcriptional regulator, TetR family
HC341_03390	ENOG4105CGU	Enoyl-CoA hydratase
HC341_03400	ENOG4108F01	MaoC domain protein
HC341_03410	ENOG4108RU0	short-chain dehydrogenase reductase
HC341_03435	ENOG4108XG4	DNA-binding transcriptional regulator
HC341_03440	ENOG4105D9M	gamma-glutamylcysteine synthetase
HC341_03460	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HC341_03465	ENOG4108JPW	Aminotransferase
HC341_03470	ENOG4107UX3	phosphatidylethanolamine N-methyltransferase
HC341_03490	ENOG4105CHM	Aminotransferase
HC341_03495	ENOG41060WC	Enoyl-CoA hydratase
HC341_03500	ENOG4105E39	Enoyl-CoA hydratase
HC341_03505	ENOG4105CEY	Amp-dependent synthetase and ligase
HC341_03510	ENOG4105K4P	CoA-binding domain protein
HC341_03530	ENOG4105XEA	Tetr family transcriptional regulator
HC341_03535	ENOG4105K6S	Short-chain dehydrogenase reductase Sdr
HC341_03555	ENOG4107T9Q	phosphonate abc transporter
HC341_03560	ENOG4105D5T	phosphonate abc transporter
HC341_03565	ENOG4105S7S	phosphonate abc transporter
HC341_03575	ENOG41080XP	Cbs domain
HC341_03590	ENOG4107VAM	peptidase, m28
HC341_03595	ENOG4105K5M	30s ribosomal protein S16
HC341_03600	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
HC341_03605	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
HC341_03610	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
HC341_03630	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HC341_03640	ENOG4105CH5	extracellular solute-binding protein, family 7
HC341_03645	ENOG4105C26	Dehydrogenase
HC341_03650	ENOG41063TF	transcriptional regulator (AraC
HC341_03655	ENOG4105C0A	alcohol dehydrogenase
HC341_03660	ENOG4105EAC	phosphoserine phosphatase
HC341_03665	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HC341_03675	ENOG4105E0X	reductase
HC341_03680	ENOG4105C7K	acetolactate synthase
HC341_03690	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
HC341_03695	ENOG4105K7U	Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization (By similarity)
HC341_03700	ENOG4107QMS	site-determining protein
HC341_03705	ENOG4105VJP	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell (By similarity)
HC341_03710	ENOG4105E9H	Lytic Murein transglycosylase
HC341_03715	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
HC341_03725	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HC341_03730	ENOG4107RZZ	dna polymerase iii epsilon subunit
HC341_03735	ENOG4105DFC	had-superfamily hydrolase, subfamily ia, variant
HC341_03770	ENOG4105Z8H	single-stranded DNA-binding protein
HC341_03810	ENOG4105W5Q	DNA repair protein (RadC
HC341_03820	ENOG4105DCY	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide (By similarity)
HC341_03830	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
HC341_03835	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HC341_03950	ENOG4105C94	Transporter
HC341_04005	ENOG4108YYC	ycei family
HC341_04020	ENOG4105VT3	DNA binding domain protein, excisionase family
HC341_04035	ENOG41081XG	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HC341_04040	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
HC341_04045	ENOG4107QM5	aconitate hydratase
HC341_04065	ENOG4105CNG	UPF0061 protein
HC341_04080	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HC341_04085	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HC341_04140	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
HC341_04165	ENOG4105CQB	FAD linked oxidase domain protein
HC341_04170	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HC341_04180	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HC341_04260	ENOG4105F5W	AtP-binding protein
HC341_04265	ENOG4105D70	Integrase catalytic subunit
HC341_04300	ENOG4107QJE	Chromosome Partitioning Protein
HC341_04310	ENOG4105DGU	Histone deacetylase
HC341_04315	ENOG4105EA8	2-Nitropropane dioxygenase
HC341_04345	ENOG4105KME	endoribonuclease L-psp
HC341_04350	ENOG4105F9F	transposase
HC341_04360	ENOG4105E5Q	amino acid AbC transporter
HC341_04385	ENOG4108KDQ	Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons (By similarity)
HC341_04400	ENOG4105CKI	cobalamin synthesis protein
HC341_04430	ENOG4105CY2	Citrate transporter
HC341_04500	ENOG41074FZ	May increase the rate of spontaneous hydrolysis of aminoacrylate to malonic semialdehyde. Required to remove a toxic intermediate produce in the pyrimidine nitrogen degradation (By similarity)
HC341_04510	ENOG4105J7D	transcriptional regulator
HC341_04535	ENOG4105CDA	abc transporter atp-binding protein
HC341_04540	ENOG4105E5Q	amino acid AbC transporter
HC341_04545	ENOG4107R0W	ABC transporter
HC341_04565	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
HC341_04585	ENOG4105KWW	Biogenesis protein
HC341_04590	ENOG4107QX9	Thiol disulfide interChange protein
HC341_04595	ENOG4105DA4	cytochrome c-type biogenesis protein
HC341_04600	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
HC341_04610	ENOG41060IM	Heme exporter protein
HC341_04615	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
HC341_04620	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
HC341_04625	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
HC341_04630	ENOG4105D74	hydrolase
HC341_04645	ENOG4108YZN	class I peptide chain release factor
HC341_04665	ENOG4105BZU	Histidine kinase
HC341_04670	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
HC341_04675	ENOG4105CHV	Transcription elongation factor NusA
HC341_04680	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
HC341_04685	ENOG4105KG7	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
HC341_04690	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
HC341_04695	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
HC341_04700	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
HC341_04705	ENOG4105VEQ	Cold shock protein
HC341_04710	ENOG4105DNZ	Alpha Beta Hydrolase
HC341_04715	ENOG4105BZU	Histidine kinase
HC341_04725	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HC341_04730	ENOG4108UKI	Enoyl-CoA hydratase
HC341_04740	ENOG4105C0Z	ABC transporter
HC341_04745	ENOG4105C32	Amino acid ABC transporter (Permease)
HC341_04760	ENOG4108IV0	ABC, transporter
HC341_04765	ENOG4108IQE	Amp-dependent synthetase and ligase
HC341_04770	ENOG4105C1G	acyl-Coa dehydrogenase
HC341_04795	ENOG4105CEY	Amp-dependent synthetase and ligase
HC341_04810	ENOG4105CTB	Polyprenyl synthetase
HC341_04815	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HC341_04820	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HC341_04825	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HC341_04830	ENOG4105D0M	Protease HtpX homolog
HC341_04835	ENOG4105BZU	Histidine kinase
HC341_04845	ENOG4105CK3	Lysine 2,3-aminomutase YodO family protein
HC341_04850	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
HC341_04855	ENOG4105CAP	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P (By similarity)
HC341_04860	ENOG4105ED1	spovr family
HC341_04865	ENOG4106AKX	UPF0229 protein
HC341_04870	ENOG4105CYN	Serine protein kinase
HC341_04875	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
HC341_04885	ENOG4105VFK	BolA family
HC341_04890	ENOG4105K9H	YciI-like protein
HC341_04895	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
HC341_04900	ENOG4105C31	Tryptophanyl-tRNA synthetase
HC341_04910	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
HC341_04915	ENOG4105FE9	pseudouridine synthase
HC341_04935	ENOG4105UBK	short-chain dehydrogenase reductase
HC341_04945	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HC341_04950	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HC341_04955	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
HC341_04960	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
HC341_04975	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
HC341_04980	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
HC341_04985	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
HC341_04990	ENOG4108JQ1	Dehydrogenase
HC341_04995	ENOG4105CQC	Prephenate dehydratase
HC341_05000	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HC341_05005	ENOG4105EVN	Prephenate dehydrogenase
HC341_05010	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
HC341_05015	ENOG4105CAT	Cytidine monophosphate kinase
HC341_05020	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
HC341_05025	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HC341_05035	ENOG4105CFV	Tetratricopeptide repeat protein
HC341_05040	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
HC341_05055	ENOG4105DJH	phosphate
HC341_05060	ENOG4105C8U	phosphate abc transporter
HC341_05065	ENOG4105E2Z	phosphate ABC transporter (Permease
HC341_05070	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HC341_05075	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
HC341_05090	ENOG4105BZU	Histidine kinase
HC341_05095	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HC341_05100	ENOG4105S7S	phosphonate abc transporter
HC341_05105	ENOG4105D5T	phosphonate abc transporter
HC341_05115	ENOG4105E2K	Glycosyl transferase (Group 1
HC341_05125	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HC341_05150	ENOG4107QVT	Binding-protein-dependent transport systems, inner membrane component
HC341_05185	ENOG4105CEY	Amp-dependent synthetase and ligase
HC341_05190	ENOG4105CHU	acetyl-coa acetyltransferase
HC341_05195	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HC341_05210	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HC341_05215	ENOG4108UKI	Enoyl-CoA hydratase
HC341_05220	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HC341_05230	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HC341_05235	ENOG4105E55	glycerol-3-phosphate acyltransferase
HC341_05245	ENOG4108IND	Tetr family transcriptional regulator
HC341_05255	ENOG4105DP0	ferredoxin-NADP reductase
HC341_05280	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HC341_05310	ENOG4105E09	nadh pyrophosphatase
HC341_05325	ENOG4107RT3	EamA-like transporter family
HC341_05335	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
HC341_05360	ENOG4105DJ4	phosphatidylserine decarboxylase
HC341_05365	ENOG4108ZX6	Electron transport protein SCO1 SenC
HC341_05370	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
HC341_05375	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
HC341_05380	ENOG4105D8G	Major Facilitator superfamily
HC341_05385	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HC341_05390	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
HC341_05395	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
HC341_05400	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
HC341_05415	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
HC341_05420	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HC341_05425	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
HC341_05430	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
HC341_05435	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
HC341_05445	ENOG4105E96	Colicin v production protein
HC341_05450	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
HC341_05455	ENOG4105C28	cystathionine
HC341_05460	ENOG4105D1Z	hydroxypyruvate reductase
HC341_05475	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
HC341_05480	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
HC341_05485	ENOG41077A9	carbonic anhydrase
HC341_05495	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HC341_05515	ENOG4105CSM	endonuclease III
HC341_05520	ENOG4105DZB	Electron transport complex
HC341_05530	ENOG4108UQQ	Electron transport complex
HC341_05545	ENOG4108R3D	Electron transport complex
HC341_05555	ENOG4105DGN	Electron transport complex
HC341_05560	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HC341_05565	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
HC341_05580	ENOG4105DHP	deoxycytidine triphosphate deaminase
HC341_05610	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
HC341_05615	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
HC341_05640	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HC341_05645	ENOG4107S2Z	UPF0761 membrane protein
HC341_05650	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
HC341_05655	ENOG4106RE7	Cytochrome
HC341_05705	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HC341_05750	ENOG4105QAX	Iron-sulfur
HC341_05770	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
HC341_05775	ENOG4107PU6	Membrane
HC341_05815	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
HC341_05830	ENOG4105BZU	Histidine kinase
HC341_05835	ENOG41065CD	Exported protein
HC341_05860	ENOG4108HRK	Histidine kinase
HC341_05865	ENOG4108VAC	response regulator
HC341_05870	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HC341_05875	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
HC341_05880	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
HC341_05910	ENOG4105E7A	Glutamine amidotransferase
HC341_05920	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HC341_05925	ENOG4105E0C	molybdate abc transporter
HC341_05935	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HC341_05940	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HC341_05945	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HC341_05960	ENOG4105KJM	monovalent cation h antiporter subunit g
HC341_05975	ENOG4107QUY	Guanine deaminase
HC341_05985	ENOG4105CJW	magnesium transporter
HC341_05990	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HC341_05995	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
HC341_06000	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
HC341_06005	ENOG4105KJM	monovalent cation h antiporter subunit g
HC341_06010	ENOG41080TA	Multiple resistance and ph regulation protein f
HC341_06015	ENOG4105SC1	monovalent cation H antiporter subunit E
HC341_06020	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HC341_06025	ENOG4105MKQ	Monovalent cation H antiporter subunit C
HC341_06030	ENOG4105HC0	Na H antiporter
HC341_06035	ENOG4105D65	subunit l
HC341_06040	ENOG4105EIE	fructose-bisphosphate aldolase
HC341_06095	ENOG4105C5W	Aldolase
HC341_06125	ENOG4108J8Q	Catalyzes the facilitated diffusion of 2-acyl-glycero-3- phosphoethanolamine (2-acyl-GPE) into the cell (By similarity)
HC341_06160	ENOG4105DWV	Homoserine O-trans-acetylase
HC341_06180	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
HC341_06190	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
HC341_06195	ENOG4105CJ1	ABC, transporter
HC341_06200	ENOG4107QWP	ABC-2 type transporter
HC341_06205	ENOG4105CMI	transporter
HC341_06210	ENOG4105C59	p-type ATPase
HC341_06275	ENOG4105PGM	cation diffusion facilitator family transporter
HC341_06295	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HC341_06330	ENOG4105CYW	agmatinase
HC341_06335	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
HC341_06340	ENOG4105CYW	agmatinase
HC341_06345	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
HC341_06360	ENOG4105EAD	ABC transporter
HC341_06365	ENOG4105E5Q	amino acid AbC transporter
HC341_06370	ENOG4105EAB	amino acid AbC transporter
HC341_06385	ENOG41082AG	Plasmid maintenance system antidote protein
HC341_06405	ENOG4105VT3	DNA binding domain protein, excisionase family
HC341_06440	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HC341_06450	ENOG4105ETX	regulatoR
HC341_06460	ENOG4105BZU	Histidine kinase
HC341_06465	ENOG4105BZU	Histidine kinase
HC341_06500	ENOG4105BZU	Histidine kinase
HC341_06515	ENOG4105F5W	AtP-binding protein
HC341_06520	ENOG4105BZU	Histidine kinase
HC341_06525	ENOG4105E9K	Isocitrate dehydrogenase
HC341_06530	ENOG4105M08	Membrane
HC341_06535	ENOG4105CQZ	Histidine kinase
HC341_06565	ENOG41082YX	Transcriptional regulator, arsr family
HC341_06570	ENOG4108UXE	Protein tyrosine phosphatase
HC341_06575	ENOG4105D6J	arsenicaL-resistance protein
HC341_06585	ENOG41068KF	Universal stress protein
HC341_06595	ENOG4105CAU	Arsenical resistance protein, ArsH
HC341_06605	ENOG4105CHU	acetyl-coa acetyltransferase
HC341_06610	ENOG4108YZY	peptidylprolyl cis-trans isomerase
HC341_06625	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
HC341_06630	ENOG4105C3J	Cysteine desulfurase
HC341_06645	ENOG4105BZU	Histidine kinase
HC341_06650	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HC341_06670	ENOG4108T5I	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
HC341_06695	ENOG4105CAH	Chromate
HC341_06700	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
HC341_06705	ENOG4105DBV	ornithine carbamoyltransferase
HC341_06710	ENOG4105C8Y	Acetylornithine aminotransferase
HC341_06715	ENOG4105M2J	Glutaredoxin
HC341_06720	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HC341_06730	ENOG4105EKE	dihydroorotase
HC341_06735	ENOG4108Z0R	Transferase
HC341_06750	ENOG4107QPD	alcohol dehydrogenase
HC341_06755	ENOG4105CDH	Citrulline--aspartate ligase
HC341_06760	ENOG4105BZU	Histidine kinase
HC341_06775	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
HC341_06780	ENOG4105C1G	acyl-Coa dehydrogenase
HC341_06785	ENOG4105CHU	acetyl-coa acetyltransferase
HC341_06795	ENOG4105CEY	Amp-dependent synthetase and ligase
HC341_06840	ENOG4105DQ2	Is probably involved in the electron transfer between its heme and the molybdenum cofactor of the reductase catalytic subunit YedY (By similarity)
HC341_06845	ENOG4105CCD	The exact function is not known. Can catalyze the reduction of a variety of substrates like dimethyl sulfoxide, trimethylamine N-oxide, phenylmethyl sulfoxide and L-methionine sulfoxide. Cannot reduce cyclic N-oxides. Shows no activity as sulfite oxidase (By similarity)
HC341_06850	ENOG4105CA0	peroxidase
HC341_06855	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
HC341_06860	ENOG4107TNW	(Aminomethyl transferase) family protein
HC341_06875	ENOG4105C8S	subunit m
HC341_06880	ENOG4108JPZ	Monovalent cation H antiporter subunit D
HC341_06895	ENOG4105KJM	monovalent cation h antiporter subunit g
HC341_06920	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
HC341_06935	ENOG4105D6P	C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex (By similarity)
HC341_06955	ENOG4105C59	p-type ATPase
HC341_06960	ENOG4106PMH	Extracellular solute-binding protein family 3
HC341_07010	ENOG4105CNG	UPF0061 protein
HC341_07030	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HC341_07045	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
HC341_07150	ENOG4108VVQ	metallophosphoesterase
HC341_07155	ENOG4108R1E	Serine threonine protein phosphatase 1
HC341_07175	ENOG410756H	nucleotidyltransferase
HC341_07220	ENOG4107QMH	DNA methylase
HC341_07235	ENOG4108R1E	Serine threonine protein phosphatase 1
HC341_07245	ENOG4108VVQ	metallophosphoesterase
HC341_07255	ENOG4105MEW	serine threonine protein phosphatase
HC341_07370	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HC341_07375	ENOG4105DSY	exodeoxyribonuclease V, gamma
HC341_07380	ENOG4107QKA	exodeoxyribonuclease V beta
HC341_07385	ENOG4107QYX	exodeoxyribonuclease v alpha
HC341_07440	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
HC341_07445	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HC341_07450	ENOG4105DMF	Dehydrogenase
HC341_07455	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
HC341_07460	ENOG4105CW7	secretion protein, HlyD family
HC341_07465	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HC341_07475	ENOG4107S76	domain protein
HC341_07500	ENOG4107QN2	dihydrolipoyl dehydrogenase
HC341_07520	ENOG4108IV0	ABC, transporter
HC341_07525	ENOG4105D5T	phosphonate abc transporter
HC341_07535	ENOG4105C32	Amino acid ABC transporter (Permease)
HC341_07550	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HC341_07555	ENOG4105BZU	Histidine kinase
HC341_07585	ENOG4105BZU	Histidine kinase
HC341_07595	ENOG4108JUA	Transcriptional regulator
HC341_07615	ENOG4107QZF	nitrite reductase NADPH large subunit
HC341_07625	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
HC341_07640	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
HC341_07655	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
HC341_07660	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
HC341_07665	ENOG4105VIE	preprotein translocase, subunit YajC
HC341_07670	ENOG4107QN8	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HC341_07675	ENOG4107RAB	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
HC341_07685	ENOG4108URH	decarboxylase
HC341_07710	ENOG4105VFU	Rna-binding protein
HC341_07725	ENOG4105ECY	inositol monophosphatase
HC341_07730	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
HC341_07740	ENOG4105C3J	Cysteine desulfurase
HC341_07750	ENOG4108Z4V	iron-sulfur cluster assembly
HC341_07755	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
HC341_07760	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
HC341_07765	ENOG41090FY	type IV pilus biogenesis stability protein PilW
HC341_07775	ENOG4105CUT	histidyl-tRNA synthetase
HC341_07780	ENOG4105N21	Membrane
HC341_07785	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HC341_07800	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
HC341_07810	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
HC341_07830	ENOG4105E3A	(ABC) transporter
HC341_07835	ENOG4105DA5	(ABC) transporter
HC341_07845	ENOG4105CHF	Glutathione S-transferase
HC341_07850	ENOG4105DR5	peptidase
HC341_07855	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
HC341_07860	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
HC341_07865	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
HC341_07870	ENOG4108Z6B	deaminase
HC341_07875	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HC341_07890	ENOG4105EWK	phytoene
HC341_07905	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HC341_07910	ENOG4105CKI	cobalamin synthesis protein
HC341_07915	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HC341_07920	ENOG4105CHU	acetyl-coa acetyltransferase
HC341_07925	ENOG4105DRR	Transcriptional regulator, GntR family
HC341_07935	ENOG4105BZU	Histidine kinase
HC341_07940	ENOG4108V7B	Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide (By similarity)
HC341_07945	ENOG4105D7T	ABC transporter
HC341_07965	ENOG4105WMR	Protein CrcB homolog
HC341_07970	ENOG4105WMR	Protein CrcB homolog
HC341_07975	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
HC341_07985	ENOG4105DIN	metallophosphoesterase
HC341_08020	ENOG4105CVE	Lytic murein transglycosylase
HC341_08035	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HC341_08040	ENOG4105CH5	extracellular solute-binding protein, family 7
HC341_08045	ENOG4107XDR	Lactoylglutathione lyase
HC341_08060	ENOG4107XM9	(LipO)protein
HC341_08070	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
HC341_08080	ENOG4105EZ6	Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA (By similarity)
HC341_08085	ENOG4107QX8	SPFH domain, Band 7 family protein
HC341_08090	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
HC341_08095	ENOG4105T95	Thiol disulfide interChange protein
HC341_08100	ENOG4108Z4U	Ferredoxin
HC341_08105	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
HC341_08115	ENOG4107XID	2'-5' rna ligase
HC341_08120	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
HC341_08125	ENOG4105Y3E	Modulates RecA activity (By similarity)
HC341_08130	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HC341_08135	ENOG4105CFH	Aspartokinase
HC341_08140	ENOG4105VM8	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding (By similarity)
HC341_08165	ENOG4105BZU	Histidine kinase
HC341_08175	ENOG4107QMP	dna polymerase iii subunits gamma and tau
HC341_08180	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
HC341_08185	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
HC341_08190	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
HC341_08200	ENOG4105KHC	sulfurtransferase
HC341_08205	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HC341_08210	ENOG4105EU8	FAD linked oxidase domain protein
HC341_08215	ENOG4105CQB	FAD linked oxidase domain protein
HC341_08225	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
HC341_08240	ENOG4105F8C	transglutaminase domain-containing protein
HC341_08250	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
HC341_08255	ENOG4108VYJ	response regulator receiver protein
HC341_08260	ENOG4105DR5	peptidase
HC341_08270	ENOG4105EIY	sodium-type flagellar protein motY
HC341_08280	ENOG4105BZU	Histidine kinase
HC341_08290	ENOG4105BZU	Histidine kinase
HC341_08320	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
HC341_08325	ENOG4105C8J	)-transporter
HC341_08330	ENOG4108Z1B	Cyclase dehydrase
HC341_08340	ENOG4105YRI	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
HC341_08345	ENOG41090R7	Ferric uptake
HC341_08350	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
HC341_08355	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
HC341_08360	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
HC341_08365	ENOG4105CFG	Acts as a chaperone (By similarity)
HC341_08370	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HC341_08375	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
HC341_08380	ENOG4108PCN	EamA-like transporter family
HC341_08385	ENOG4108IPJ	Membrane
HC341_08390	ENOG4105EMK	carboxylate amino acid amine transporter
HC341_08395	ENOG4105BZU	Histidine kinase
HC341_08420	ENOG4105C0D	helicase
HC341_08440	ENOG4105C0D	helicase
HC341_08460	ENOG4108YXQ	IS66 Orf2 family protein
HC341_08480	ENOG4105F9F	transposase
HC341_08505	ENOG4106H3A	restriction
HC341_08520	ENOG4106WTF	Glycosyl transferase, family 2
HC341_08565	ENOG4105D70	Integrase catalytic subunit
HC341_08570	ENOG4105F5W	AtP-binding protein
HC341_08585	ENOG4105F5W	AtP-binding protein
HC341_08600	ENOG41080HT	Transcriptional regulator, arsr family
HC341_08615	ENOG4105K63	Thioredoxin
HC341_08620	ENOG4105C3M	thioredoxin reductase
HC341_08625	ENOG4105E7A	Glutamine amidotransferase
HC341_08630	ENOG4105X1V	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
HC341_08635	ENOG4105DXI	Major Facilitator superfamily
HC341_08645	ENOG4105CR7	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA (By similarity)
HC341_08655	ENOG4108YYC	ycei family
HC341_08665	ENOG4105BZU	Histidine kinase
HC341_08670	ENOG4105BZU	Histidine kinase
HC341_08675	ENOG4105BZU	Histidine kinase
HC341_08680	ENOG4105BZU	Histidine kinase
HC341_08710	ENOG4108RAV	Conserved protein
HC341_08730	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HC341_08735	ENOG4105C0A	alcohol dehydrogenase
HC341_08745	ENOG4108RAV	Conserved protein
HC341_08800	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
HC341_08805	ENOG4105CV8	reductase
HC341_08810	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
HC341_08830	ENOG4105ECK	Fatty Acid Desaturase
HC341_08840	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HC341_08885	ENOG4107RD7	Flagellar Motor Protein, MotA
HC341_08890	ENOG4105ER2	Ompa motb domain protein
HC341_08900	ENOG4105D4P	Coproporphyrinogen iii oxidase
HC341_08905	ENOG4105WD1	Membrane
HC341_08910	ENOG4105NXH	GreA GreB family elongation factor
HC341_08925	ENOG4105FSR	swimming returnes to normal when residues 206-207 are both mutated to Ala. Overexpression also leads to a reduction in flagellar abundance and a 20-fold increase in c-di- GMP levels in vivo. Required for aminoglycoside-mediated induction of biofilm formation, it also plays a lesser role in biofilm production in response to other classes of translation inhibitors. The c-di-GMP produced by this enzyme up-regulates poly-GlcNAc production as well as the biofilm synthesis protein PgaD, although c-di-GMP is probably not the main inducing principle. Cyclic-di- GMP is a second messenger which controls cell surface-associated traits in bacteria
HC341_08935	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
HC341_08945	ENOG4105ETT	transcriptional Regulator, LysR family
HC341_08965	ENOG4105CHQ	Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella (By similarity)
HC341_08975	ENOG4105C8P	)-transporter
HC341_09010	ENOG4105DGU	Histone deacetylase
HC341_09015	ENOG4108UPT	UPF0178 protein
HC341_09025	ENOG4108Z4U	Ferredoxin
HC341_09035	ENOG4105KPV	Transcriptional regulator
HC341_09040	ENOG4108IRC	dna polymerase iii
HC341_09060	ENOG4107QN1	sodium solute
HC341_09075	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HC341_09085	ENOG4105BZU	Histidine kinase
HC341_09095	ENOG4105E5W	Transporter
HC341_09115	ENOG4105D22	carbon starvation protein
HC341_09125	ENOG4105D0U	Arsenite-activated ATPase (ArsA)
HC341_09135	ENOG4105DSF	transport protein
HC341_09140	ENOG4105IU3	Glutathione S-transferase
HC341_09145	ENOG4105DR9	pseudouridine synthase
HC341_09150	ENOG4105BZU	Histidine kinase
HC341_09160	ENOG4108JJ7	ABC transporter
HC341_09165	ENOG4105CBX	hi0933 family
HC341_09185	ENOG4108UT2	hemolysin iii
HC341_09215	ENOG4105CS1	NAD(P)H quinone oxidoreductase
HC341_09220	ENOG41090MY	MarR family Transcriptional regulator
HC341_09225	ENOG4105VTS	DnaJ-like, subfamily C
HC341_09235	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
HC341_09245	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HC341_09250	ENOG4105Q24	Signal transduction protein, which is a major regulator of staphylococcal pathogenesis. Phosphorylated TRAP leads to the activation of agr system and consequent RNAIII synthesis resulting in the expression of several virulence factors. Upregulates the expression of most toxins and genes known to be necessary for biofilm formation
HC341_09255	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
HC341_09260	ENOG4108JJ8	(ABC) transporter
HC341_09265	ENOG4108JJ9	ABC, transporter
HC341_09270	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HC341_09275	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HC341_09285	ENOG4107S7U	Sulfide dehydrogenase
HC341_09290	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
HC341_09295	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
HC341_09300	ENOG4105C4M	(Ubiquinol oxidase) subunit I
HC341_09310	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
HC341_09335	ENOG4105C1J	atp-dependent rna helicase
HC341_09345	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
HC341_09350	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
HC341_09355	ENOG4105C5H	ABC transporter
HC341_09360	ENOG4105CPI	Metal Dependent Phosphohydrolase
HC341_09365	ENOG41069P5	Protein slyX homolog
HC341_09370	ENOG4105C5H	ABC transporter
HC341_09375	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
HC341_09385	ENOG4105C9U	ATP-dependent DNA helicase RecQ
HC341_09400	ENOG4105DHJ	ABC, transporter
HC341_09410	ENOG4105DB7	PHP domain protein
HC341_09420	ENOG4108NVR	Methyl-accepting chemotaxis
HC341_09470	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
HC341_09475	ENOG4105DAA	L-lactate
HC341_09485	ENOG4107QR9	Iron-sulfur cluster binding protein
HC341_09490	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
HC341_09495	ENOG41090A4	Pterin carbinolamine dehydratase
HC341_09530	ENOG4107QM5	aconitate hydratase
HC341_09535	ENOG41075W9	High frequency lysogenization protein HflD homolog
HC341_09540	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
HC341_09560	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
HC341_09565	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HC341_09570	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
HC341_09575	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
HC341_09580	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
HC341_09590	ENOG4105CNU	cell division protein FtsK
HC341_09595	ENOG4107TMZ	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) (By similarity)
HC341_09600	ENOG4105D1H	recombination factor protein RarA
HC341_09605	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
HC341_09610	ENOG4107R11	Transcriptional regulator
HC341_09615	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
HC341_09620	ENOG4108MN8	Membrane
HC341_09625	ENOG4105CSU	acyl-Coa dehydrogenase
HC341_09630	ENOG4105BZU	Histidine kinase
HC341_09640	ENOG4105ECA	phosphoserine phosphatase homoserine phosphotransferase bifunctional protein
HC341_09650	ENOG4105CQ7	ATP-dependent helicase
HC341_09660	ENOG4105CRK	lysyL-tRNA synthetase
HC341_09665	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
HC341_09675	ENOG410612Q	succinate dehydrogenase (cytochrome b-556 subunit)
HC341_09690	ENOG4105E33	succinate dehydrogenase
HC341_09695	ENOG4105Y75	tpr repeat protein
HC341_09705	ENOG4108IYU	L-aspartate oxidase
HC341_09710	ENOG4105EMN	RNA polymerase sigma factor
HC341_09720	ENOG4105WMJ	Positive regulator of sigma E, RseC MucC
HC341_09725	ENOG4105C0H	protease
HC341_09730	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
HC341_09735	ENOG4105C3F	Signal peptidase i
HC341_09745	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
HC341_09750	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
HC341_09755	ENOG41071DT	Involved in DNA repair and RecF pathway recombination (By similarity)
HC341_09760	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
HC341_09765	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
HC341_09770	ENOG4105BZU	Histidine kinase
HC341_09775	ENOG4105C6T	cysteine synthase
HC341_09785	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
HC341_09790	ENOG41087AY	ADP-Ribose pyrophosphatase
HC341_09805	ENOG4107QTF	adenylosuccinate lyase
HC341_09810	ENOG4105C9Q	fumarate hydratase class II
HC341_09820	ENOG4105WH1	Two component transcriptional regulator luxr family
HC341_09825	ENOG4105E50	uracil-dna glycosylase
HC341_09830	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
HC341_09835	ENOG4105BZQ	cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
HC341_09860	ENOG4105CA9	Pyruvate kinase
HC341_09865	ENOG4105C0Z	ABC transporter
HC341_09870	ENOG4108IV0	ABC, transporter
HC341_09875	ENOG4105C32	Amino acid ABC transporter (Permease)
HC341_09880	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HC341_09890	ENOG4105C8J	)-transporter
HC341_09910	ENOG4105CPP	Dehydrogenase, E1 component
HC341_09915	ENOG4107R0V	Pyruvate dehydrogenase
HC341_09920	ENOG4105C3J	Cysteine desulfurase
HC341_09925	ENOG4105F8V	Hydrolase, tatD family
HC341_09935	ENOG4107QRG	dna polymerase iii
HC341_09940	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
HC341_09945	ENOG4105HHA	aminodeoxychorismate lyase
HC341_09955	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
HC341_09960	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
HC341_09965	ENOG4105CHR	reductase
HC341_09970	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
HC341_09975	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
HC341_09980	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
HC341_09985	ENOG4105VGS	50s ribosomal protein l32
HC341_09990	ENOG4105FCQ	metal-binding, possibly nucleic acid-binding protein
HC341_09995	ENOG4108UHJ	MAF-like protein
HC341_10005	ENOG4105EI2	Pseudouridine synthase
HC341_10010	ENOG4107QQB	Ribonuclease E
HC341_10015	ENOG4105KJF	protein tyrosine phosphatase
HC341_10020	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
HC341_10025	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
HC341_10030	ENOG4109015	Biopolymer transport protein exbD tolR
HC341_10040	ENOG4108EQH	DNA internalization-related competence protein ComEC Rec2
HC341_10050	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
HC341_10055	ENOG4105D60	lipoprotein releasing system transmembrane protein
HC341_10060	ENOG4105PW4	Sugar fermentation stimulation protein homolog
HC341_10065	ENOG4105DWY	Agmatine deiminase
HC341_10075	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HC341_10080	ENOG4108JA2	transcriptioN-repair coupling factor
HC341_10095	ENOG4105DXN	mazG family
HC341_10110	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
HC341_10115	ENOG4105DWF	phosphomethylpyrimidine kinase
HC341_10125	ENOG4105F8V	Hydrolase, tatD family
HC341_10130	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HC341_10150	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
HC341_10155	ENOG4105ERH	Fumarylacetoacetate hydrolase
HC341_10160	ENOG4105P8F	nudix hydrolase
HC341_10190	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
HC341_10230	ENOG4107QHF	type ii secretion system protein e
HC341_10275	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
HC341_10285	ENOG410832A	alpha/beta hydrolase fold
HC341_10295	ENOG4105CD8	aminopeptidase N
HC341_10300	ENOG4105CN1	protease
HC341_10305	ENOG4105BZU	Histidine kinase
HC341_10310	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
HC341_10325	ENOG4105D6E	homoserine dehydrogenase
HC341_10330	ENOG4105CHM	Aminotransferase
HC341_10340	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HC341_10345	ENOG4108K5P	(LipO)protein
HC341_10350	ENOG4108UM1	dedA family
HC341_10355	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HC341_10360	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
HC341_10365	ENOG4108DG9	Smr protein MutS2
HC341_10370	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
HC341_10375	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
HC341_10380	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
HC341_10385	ENOG4105XX3	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic (By similarity)
HC341_10390	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
HC341_10395	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
HC341_10400	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
HC341_10405	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
HC341_10410	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
HC341_10415	ENOG4105C0B	DNA polymerase III (alpha subunit)
HC341_10420	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HC341_10435	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
HC341_10440	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HC341_10445	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HC341_10450	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
HC341_10455	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HC341_10470	ENOG4105DZP	Membrane-associated zinc metalloprotease
HC341_10475	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
HC341_10480	ENOG4105KNE	Phosphatidate cytidylyltransferase
HC341_10485	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
HC341_10490	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
HC341_10495	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
HC341_10500	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
HC341_10505	ENOG4105CE9	30S ribosomal protein S2
HC341_10510	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
HC341_10525	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
HC341_10530	ENOG4105KUZ	arsenate reductase
HC341_10535	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
HC341_10545	ENOG4105DEN	Luciferase family
HC341_10550	ENOG41066VF	YeeE YedE family protein
HC341_10565	ENOG4105CB2	alcohol dehydrogenase
HC341_10570	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
HC341_10575	ENOG4105KRS	Proteinase inhibitor
HC341_10585	ENOG4108R96	Methyltransferase, YaeB family
HC341_10590	ENOG4105C4R	Atp-dependent dna helicase
HC341_10600	ENOG4108I5C	dEAD DEAH box helicase
HC341_10605	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
HC341_10610	ENOG4107QP3	malate synthase g
HC341_10620	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
HC341_10630	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
HC341_10695	ENOG4105C94	Transporter
HC341_10705	ENOG4107RZZ	dna polymerase iii epsilon subunit
HC341_10715	ENOG4107YZX	Universal stress protein
HC341_10720	ENOG4105C8Q	Methyl-accepting chemotaxis
HC341_10725	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HC341_10740	ENOG41076HS	cation diffusion facilitator family transporter
HC341_10745	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
HC341_10750	ENOG4105EG6	Saccharopine dehydrogenase
HC341_10765	ENOG4105N1F	Hnh endonuclease
HC341_10805	ENOG4105BZU	Histidine kinase
HC341_10830	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
HC341_10835	ENOG4108MFN	small subunit of hydrogenase-3, iron-sulfur protein (part of formate hydrogenlyase (FHL) complex)
HC341_10850	ENOG4107SKI	cobyrinic Acid a,c-diamide synthase
HC341_10860	ENOG4105CBS	Chea signal transduction histidine kinase
HC341_10865	ENOG4108VYJ	response regulator receiver protein
HC341_10870	ENOG4105BZU	Histidine kinase
HC341_10880	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HC341_10885	ENOG4108V3W	Chemotaxis protein, CheW
HC341_10890	ENOG4105C8Q	Methyl-accepting chemotaxis
HC341_10895	ENOG4105BZU	Histidine kinase
HC341_10900	ENOG4105BZU	Histidine kinase
HC341_10905	ENOG4108KXV	response regulator
HC341_10915	ENOG4108W2P	Methyl-accepting chemotaxis
HC341_10920	ENOG4108VYJ	response regulator receiver protein
HC341_10925	ENOG4105BZU	Histidine kinase
HC341_10935	ENOG4105EGB	membrane protein DamX
HC341_10940	ENOG4105BZU	Histidine kinase
HC341_10960	ENOG4108V3W	Chemotaxis protein, CheW
HC341_10970	ENOG4107QJE	Chromosome Partitioning Protein
HC341_10975	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
HC341_10985	ENOG4108KCC	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) (By similarity)
HC341_10990	ENOG4108VYJ	response regulator receiver protein
HC341_10995	ENOG4105DN4	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HC341_11005	ENOG4105FZW	flagellar biosynthesis regulator FlhF
HC341_11010	ENOG4105D7B	Flagellar biosynthesis protein flha
HC341_11015	ENOG4105D00	flagellar biosynthetic protein flhB
HC341_11020	ENOG4105D19	Role in flagellar biosynthesis (By similarity)
HC341_11025	ENOG4105VS8	Flagellar biosynthetic protein fliq
HC341_11030	ENOG4105CN7	Flagellar biosynthetic protein FliP
HC341_11035	ENOG4105VTB	flagellar biosynthesis protein fliO
HC341_11040	ENOG4105DD5	Flagellar motor switch protein
HC341_11045	ENOG4105D24	FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HC341_11070	ENOG4108JIR	Flagellum-specific ATP synthase
HC341_11080	ENOG4105CS3	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation (By similarity)
HC341_11085	ENOG4105C1F	The M ring may be actively involved in energy transduction (By similarity)
HC341_11120	ENOG4105MQ3	flagellar protein FliS
HC341_11125	ENOG4105DTS	flagellar hook-associated
HC341_11145	ENOG4105BZU	Histidine kinase
HC341_11150	ENOG4105C9X	ppx gppa phosphatase
HC341_11155	ENOG410902C	phosphohistidine phosphatase, SixA
HC341_11160	ENOG4105CI3	gtp-binding protein typa
HC341_11175	ENOG4105CFU	surface antigen
HC341_11180	ENOG4105E27	serine threonine protein kinase
HC341_11185	ENOG4107QPA	Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity)
HC341_11205	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
HC341_11235	ENOG4108HQS	Glycine betaine
HC341_11240	ENOG4108IJ7	Glycine betaine
HC341_11250	ENOG4108W2Q	Cytochrome d ubiquinol oxidase subunit III
HC341_11280	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
HC341_11290	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
HC341_11295	ENOG4105BZU	Histidine kinase
HC341_11340	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
HC341_11345	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
HC341_11350	ENOG4105EFU	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (By similarity)
HC341_11375	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HC341_11390	ENOG4105C1G	acyl-Coa dehydrogenase
HC341_11400	ENOG4105FYV	Amp nucleosidase
HC341_11410	ENOG4105GRZ	Ycii-related protein
HC341_11415	ENOG4105GRZ	Ycii-related protein
HC341_11420	ENOG4105CHP	RNA polymerase
HC341_11430	ENOG4105E39	Enoyl-CoA hydratase
HC341_11450	ENOG41084HI	prevent-host-death family
HC341_11460	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
HC341_11475	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
HC341_11490	ENOG41076YT	nitrate reductase, gamma subunit
HC341_11495	ENOG4108NZN	Respiratory nitrate reductase 2 delta chain
HC341_11505	ENOG4105CRU	nitrate reductase, alpha subunit
HC341_11510	ENOG41068KF	Universal stress protein
HC341_11545	ENOG4105BZU	Histidine kinase
HC341_11550	ENOG4105WH1	Two component transcriptional regulator luxr family
HC341_11555	ENOG4108YY7	Invasion gene expression up-regulator SirB
HC341_11565	ENOG4105C0Z	ABC transporter
HC341_11575	ENOG4105C32	Amino acid ABC transporter (Permease)
HC341_11580	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
HC341_11590	ENOG4108IV0	ABC, transporter
HC341_11600	ENOG4108Z6Z	Transcriptional regulator
HC341_11605	ENOG4105C1G	acyl-Coa dehydrogenase
HC341_11610	ENOG4107QX3	carboxylase
HC341_11615	ENOG4108IPT	Naphthoate synthase
HC341_11625	ENOG4105CBH	Hydroxymethylglutaryl-CoA lyase
HC341_11630	ENOG4105EJQ	L-serine dehydratase
HC341_11645	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HC341_11660	ENOG4105E0X	reductase
HC341_11670	ENOG4108ZF3	Phosphatase
HC341_11685	ENOG4105UYK	outer membrane protein a
HC341_11730	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
HC341_11745	ENOG4105ECQ	AraC Family Transcriptional Regulator
HC341_11760	ENOG4105C1G	acyl-Coa dehydrogenase
HC341_11820	ENOG4108YXQ	IS66 Orf2 family protein
HC341_11830	ENOG4105E7D	Protein of unknown function (DUF3375)
HC341_11870	ENOG4105CX6	glutaminyL-tRNA synthetase
HC341_11895	ENOG4105C0D	helicase
HC341_11910	ENOG4105DFG	type I secretion outer membrane protein
HC341_11915	ENOG4107SBE	Glycosyl transferase (Group 1
HC341_11925	ENOG4105EY8	ABC transporter
HC341_11930	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HC341_11945	ENOG4108JJ6	Type I secretion system ATPase
HC341_11970	ENOG4105F5W	AtP-binding protein
HC341_11975	ENOG4105D70	Integrase catalytic subunit
HC341_11990	ENOG4106QJ6	Integrase catalytic subunit
HC341_12065	ENOG4107S90	membrAne
HC341_12085	ENOG4108YXQ	IS66 Orf2 family protein
HC341_12115	ENOG4105VGJ	Virulence-associated protein
HC341_12120	ENOG4105M0J	Toxic component of a toxin-antitoxin (TA) module. A
HC341_12185	ENOG4108YXQ	IS66 Orf2 family protein
HC341_12260	ENOG4105ESV	Glycosyl transferase, family 4
HC341_12295	ENOG4105K64	Glycosyl transferase, family 2
HC341_12455	ENOG4105CY0	Metallo-Beta-Lactamase
HC341_12480	ENOG4105VEJ	Heat shock protein
HC341_12485	ENOG4105C2X	Arabinose 5-phosphate isomerase
HC341_12490	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
HC341_12515	ENOG4107T6J	Ribulose-1,5-bisphosphate carboxylase oxygenase large subunit
HC341_12520	ENOG4105G2U	Cupin 2, conserved barrel domain protein
HC341_12525	ENOG4108UK5	Transposase
HC341_12535	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
HC341_12540	ENOG4108K1J	Transporter DctQ
HC341_12545	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HC341_12550	ENOG4105EKQ	RNA-directed DNA polymerase
HC341_12560	ENOG4105C09	Bile acid
HC341_12565	ENOG4105CEY	Amp-dependent synthetase and ligase
HC341_12585	ENOG4105CTU	Proline racemase
HC341_12610	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HC341_12665	ENOG4105EXX	Deoxyribodipyrimidine photolyase-related protein
HC341_12680	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
HC341_12685	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HC341_12690	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HC341_12705	ENOG4105K70	DNA-binding protein
HC341_12710	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
HC341_12715	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HC341_12720	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
HC341_12725	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
HC341_12735	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
HC341_12755	ENOG4105DXI	Major Facilitator superfamily
HC341_12760	ENOG4105DVT	helicase
HC341_12790	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
HC341_12800	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
HC341_12805	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
HC341_12810	ENOG4105CDU	Replicative dna helicase
HC341_12815	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
HC341_12825	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
HC341_12835	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
HC341_12840	ENOG4105C2N	RNA methyltransferase TrmH family group 3
HC341_12845	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
HC341_12855	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
HC341_12860	ENOG4105C49	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (By similarity)
HC341_12870	ENOG4105EPW	hflc protein
HC341_12875	ENOG4107QJR	hflk protein
HC341_12880	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
HC341_12885	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
HC341_12890	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
HC341_12895	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
HC341_12900	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
HC341_12905	ENOG4105K8N	protein family UPF0079, ATPase
HC341_12910	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
HC341_12915	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
HC341_12925	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
HC341_12935	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
HC341_12940	ENOG4105DJ0	Poly(A) Polymerase
HC341_12955	ENOG4108K5H	permease YjgP YjgQ family protein
HC341_12960	ENOG4108M8S	permease YjgP YjgQ family protein
HC341_12965	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
HC341_12980	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
HC341_12990	ENOG4105KEG	ribosomal-protein-alanine acetyltransferase
HC341_12995	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
HC341_13000	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
HC341_13005	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
HC341_13010	ENOG4108ZP8	Acetolactate synthase small subunit
HC341_13020	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
HC341_13025	ENOG4107SC1	transglycosylase
HC341_13030	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
HC341_13040	ENOG4105D1F	ATP-binding protein
HC341_13055	ENOG4108Z7T	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
HC341_13060	ENOG4108RIR	Molybdenum cofactor biosynthesis protein
HC341_13065	ENOG4108ZAF	Molybdopterin
HC341_13075	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
HC341_13085	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HC341_13090	ENOG4105CSU	acyl-Coa dehydrogenase
HC341_13100	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
HC341_13120	ENOG41072GX	Peptidase M22 Glycoprotease
HC341_13135	ENOG4108JPW	Aminotransferase
HC341_13140	ENOG4108Z6K	Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant (By similarity)
HC341_13160	ENOG4108IGT	Dipeptidase
HC341_13170	ENOG4105DUM	transcriptional regulator, lysR family
HC341_13185	ENOG4105DHF	Membrane
HC341_13195	ENOG4105CEY	Amp-dependent synthetase and ligase
HC341_13210	ENOG4105DVT	helicase
HC341_13220	ENOG4105BZ4	penicillin-binding protein
HC341_13225	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
HC341_13230	ENOG4108W2P	Methyl-accepting chemotaxis
HC341_13245	ENOG4105JRK	feS assembly protein SufD
HC341_13270	ENOG4108JIC	nucleoside recognition domain protein
HC341_13305	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HC341_13310	ENOG4105BZU	Histidine kinase
HC341_13345	ENOG4105CA9	Pyruvate kinase
HC341_13350	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HC341_13355	ENOG4108UHU	Aldolase
HC341_13360	ENOG4105CHC	glucokinase (EC 2.7.1.2)
HC341_13365	ENOG4105ETE	Transcriptional regulator (LacI family
HC341_13405	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
HC341_13415	ENOG4107R7Y	intracellular protease Pfpi family
HC341_13425	ENOG4108YYH	Nadph-dependent fmn reductase
HC341_13435	ENOG4105EUB	pirin domain protein
HC341_13455	ENOG4105WJX	transcriptional regulator MERR family
HC341_13460	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
HC341_13465	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
HC341_13470	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
HC341_13480	ENOG4105VJV	50s ribosomal protein L35
HC341_13485	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
HC341_13490	ENOG4105C22	threonyL-tRNA synthetase
HC341_13500	ENOG4105BZU	Histidine kinase
HC341_13525	ENOG4105FS0	cytoplasmic membrane protein
HC341_13545	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
HC341_13570	ENOG4105D8X	mechanosensitive ion channel
HC341_13585	ENOG4108V0P	LemA family
HC341_13590	ENOG4105D0M	Protease HtpX homolog
HC341_13600	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HC341_13630	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HC341_13635	ENOG4105E1F	short-chain dehydrogenase reductase
HC341_13645	ENOG4105C1G	acyl-Coa dehydrogenase
HC341_13670	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
HC341_13675	ENOG4107NPY	receptor for the septal ring structure, may anchor it to the inner-membrane (By similarity)
HC341_13690	ENOG4107YRI	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
HC341_13700	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
HC341_13720	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HC341_13725	ENOG4105CHR	reductase
HC341_13735	ENOG4108RPX	mosc domain containing protein
HC341_13755	ENOG4105DTJ	flagellar hook-associated protein
HC341_13760	ENOG4105E1Q	flagellar hook-associated protein
HC341_13765	ENOG4108ZW7	flagellar rod assembly protein muramidase flgj
HC341_13770	ENOG4105D92	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HC341_13775	ENOG4107W7W	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation (By similarity)
HC341_13780	ENOG4105CGA	flagellar basal-body rod protein FlgG
HC341_13785	ENOG4108KPB	Flagellar basal-body rod protein FlgF
HC341_13790	ENOG4105BZE	flagellar hook protein, FlgE
HC341_13800	ENOG4108ZC9	flagellar basal-body rod protein flgc
HC341_13805	ENOG4105K88	Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body (By similarity)
HC341_13810	ENOG4105BZU	Histidine kinase
HC341_13840	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
HC341_13850	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
HC341_13875	ENOG4105CHB	tonB-dependent Receptor
HC341_13895	ENOG4105C0B	DNA polymerase III (alpha subunit)
HC341_13900	ENOG4105C8N	cysteinyl-tRNA synthetase
HC341_13905	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
HC341_13910	ENOG4108S01	response regulator
HC341_13925	ENOG4107RGH	Aldehyde dehydrogenase
HC341_13940	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
HC341_13945	ENOG4105C10	Electron transfer flavoprotein
HC341_13950	ENOG4105BZJ	Electron transfer flavoprotein
HC341_13955	ENOG4105MYN	Zinc uptake regulation protein
HC341_13960	ENOG4105DFG	type I secretion outer membrane protein
HC341_13985	ENOG4105FDK	ABC transporter
HC341_14005	ENOG4107ZQV	short-chain dehydrogenase reductase
HC341_14020	ENOG4105CHU	acetyl-coa acetyltransferase
HC341_14025	ENOG4105CC9	acyl-Coa dehydrogenase
HC341_14030	ENOG4105C1G	acyl-Coa dehydrogenase
HC341_14035	ENOG4105CSU	acyl-Coa dehydrogenase
HC341_14040	ENOG4105MP9	class II Aldolase
HC341_14045	ENOG4105D78	K07001 NTE family protein
HC341_14050	ENOG4108UNV	SUF system FeS assembly protein, NifU family
HC341_14065	ENOG4107P0T	Selenium-dependent molybdenum hydroxylase system protein, YqeB family
HC341_14095	ENOG4105SWR	response regulator
HC341_14115	ENOG4105BZU	Histidine kinase
HC341_14120	ENOG4107R6F	Alpha Beta Hydrolase Fold protein
HC341_14125	ENOG4105CNG	UPF0061 protein
HC341_14135	ENOG410905X	membrane-flanked domain protein
HC341_14140	ENOG4105VK3	rdd domain containing protein
HC341_14165	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
HC341_14175	ENOG4108JU6	CBS domain protein
HC341_14180	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
HC341_14185	ENOG4108JU5	Magnesium and cobalt efflux protein
HC341_14190	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
HC341_14195	ENOG4105C9A	Phoh family
HC341_14200	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
HC341_14205	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
HC341_14210	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
HC341_14215	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
HC341_14220	ENOG4105K46	50S ribosomal protein l27
HC341_14225	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
HC341_14230	ENOG4105EAH	synthase
HC341_14265	ENOG4105CH5	extracellular solute-binding protein, family 7
HC341_14275	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HC341_14285	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HC341_14290	ENOG4107QHF	type ii secretion system protein e
HC341_14310	ENOG4105DHA	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity (By similarity)
HC341_14315	ENOG41067SF	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
HC341_14320	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HC341_14325	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
HC341_14330	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
HC341_14340	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
HC341_14345	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
HC341_14350	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
HC341_14355	ENOG4105K7E	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly (By similarity)
HC341_14360	ENOG4105CPF	Cell wall formation (By similarity)
HC341_14365	ENOG4105D4A	Cell wall formation (By similarity)
HC341_14370	ENOG4105DFU	Cell wall formation (By similarity)
HC341_14375	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
HC341_14380	ENOG4105CNI	cell division protein FtsW
HC341_14385	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
HC341_14390	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
HC341_14395	ENOG4108EQQ	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein (By similarity)
HC341_14400	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
HC341_14405	ENOG4105CJN	penicillin-binding protein
HC341_14415	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
HC341_14420	ENOG4108V6E	Cell division protein mraZ
HC341_14425	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
HC341_14430	ENOG4105E1C	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) (By similarity)
HC341_14435	ENOG41082RQ	UPF0102 protein
HC341_14440	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
HC341_14450	ENOG4105KB2	stringent starvation protein b
HC341_14455	ENOG4107MKT	Stringent starvation protein a
HC341_14460	ENOG4105EIX	cytochrome c1
HC341_14465	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HC341_14470	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
HC341_14475	ENOG4107QNR	UPF0135 protein
HC341_14480	ENOG4105C0H	protease
HC341_14485	ENOG4105CIH	Imidazole acetol-phosphate transaminase
HC341_14490	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
HC341_14495	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
HC341_14500	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
HC341_14515	ENOG4105E3I	toluene tolerance
HC341_14520	ENOG4107PE3	Mammalian cell entry related domain protein
HC341_14525	ENOG4105CY3	ABC transporter, permease
HC341_14530	ENOG4105DHJ	ABC, transporter
HC341_14535	ENOG4105FEU	K -dependent Na -Ca exchanger
HC341_14540	ENOG4105C2X	Arabinose 5-phosphate isomerase
HC341_14560	ENOG4108IUZ	ABC transporter
HC341_14565	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HC341_14570	ENOG41080QH	sigma 54 modulation protein ribosomal protein S30EA
HC341_14575	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
HC341_14580	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
HC341_14585	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
HC341_14595	ENOG41080Z8	PHOSPHOCARRIER protein
HC341_14605	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
HC341_14610	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
HC341_14625	ENOG4105C03	ribonuclease
HC341_14630	ENOG4108Z03	MAF-like protein
HC341_14635	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
HC341_14645	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
HC341_14650	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
HC341_14655	ENOG4105DJF	DNA polymerase III, delta' subunit
HC341_14665	ENOG4105C8T	Leucyl-tRNA synthetase
HC341_14685	ENOG4108Z86	Glutamine amidotransferase
HC341_14690	ENOG4105C3R	Methionine synthase
HC341_14695	ENOG4107RDP	Dehydrogenase
HC341_14720	ENOG4105C0H	protease
HC341_14725	ENOG4105NAU	thioesterase Superfamily protein
HC341_14730	ENOG4105C7B	Threonine dehydratase
HC341_14745	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
HC341_14755	ENOG4105EN6	Membrane
HC341_14780	ENOG41084UG	Pfam:DUF1458
HC341_14785	ENOG4105K78	MarR family Transcriptional regulator
HC341_14800	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
HC341_14810	ENOG4105BZU	Histidine kinase
HC341_14815	ENOG4105D8V	Glucose sorbosone dehydrogenase
HC341_14820	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
HC341_14825	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
HC341_14835	ENOG4105C1G	acyl-Coa dehydrogenase
HC341_14845	ENOG410846T	CoA-transferase family III
HC341_14850	ENOG4105CHU	acetyl-coa acetyltransferase
HC341_14860	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
HC341_14865	ENOG4105CGU	Enoyl-CoA hydratase
HC341_14870	ENOG4105E39	Enoyl-CoA hydratase
HC341_14875	ENOG4105C1G	acyl-Coa dehydrogenase
HC341_14880	ENOG4105C26	Dehydrogenase
HC341_14890	ENOG4108IV0	ABC, transporter
HC341_14905	ENOG4105C32	Amino acid ABC transporter (Permease)
HC341_14910	ENOG4105C0Z	ABC transporter
HC341_14915	ENOG4108IQE	Amp-dependent synthetase and ligase
HC341_14920	ENOG4108UUM	single-stranded DNA-binding protein
HC341_14925	ENOG4107RDB	Major Facilitator
HC341_14930	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
HC341_14935	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
HC341_14950	ENOG4108ZT0	50S ribosomal protein l17
HC341_14955	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HC341_14960	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
HC341_14965	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
HC341_14970	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
HC341_14975	ENOG41067V7	50S ribosomal protein L36
HC341_14980	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
HC341_14985	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
HC341_14990	ENOG4105VPB	50S ribosomal protein L30
HC341_14995	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
HC341_15000	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
HC341_15005	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
HC341_15010	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
HC341_15015	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
HC341_15020	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
HC341_15025	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
HC341_15030	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
HC341_15035	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
HC341_15040	ENOG41083MP	50s ribosomal protein l29
HC341_15045	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
HC341_15050	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
HC341_15055	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
HC341_15065	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
HC341_15070	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
HC341_15075	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
HC341_15080	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
HC341_15085	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
HC341_15090	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HC341_15095	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
HC341_15100	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
HC341_15105	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
HC341_15110	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HC341_15115	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
HC341_15120	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
HC341_15125	ENOG4108VZM	50s ribosomal protein L10
HC341_15130	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
HC341_15135	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
HC341_15140	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
HC341_15145	ENOG4105PM1	preprotein translocase subunit SecE
HC341_15155	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
HC341_15180	ENOG4105C8Q	Methyl-accepting chemotaxis
HC341_15190	ENOG4105C3G	gtp-binding protein
HC341_15195	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
HC341_15200	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
HC341_15205	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
HC341_15215	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
HC341_15220	ENOG4105C1U	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein (By similarity)
HC341_15225	ENOG4105DJQ	tetratricopeptide tpr_2 repeat protein
HC341_15230	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
HC341_15235	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
HC341_15245	ENOG4105FDK	ABC transporter
HC341_15260	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
HC341_15265	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
HC341_15270	ENOG4105W49	UPF0434 protein
HC341_15275	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
HC341_15280	ENOG4105D06	uba thif-type nad fad binding protein
HC341_15285	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
HC341_15290	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HC341_15295	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
HC341_15300	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
HC341_15310	ENOG4105N3I	Involved in formation and maintenance of cell shape (By similarity)
HC341_15320	ENOG4105CJN	penicillin-binding protein
HC341_15325	ENOG4105CNI	cell division protein FtsW
HC341_15330	ENOG4105CVE	Lytic murein transglycosylase
HC341_15335	ENOG4105K6T	rare lipoprotein A
HC341_15340	ENOG4105DZ1	carboxypeptidase
HC341_15345	ENOG4108Z43	UPF0250 protein
HC341_15350	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
HC341_15360	ENOG4108S0S	Nucleotidyl transferase
HC341_15365	ENOG4105EHM	Aminoglycoside phosphotransferase
HC341_15370	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
HC341_15375	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
HC341_15380	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
HC341_15385	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HC341_15390	ENOG41081QV	Universal stress protein
HC341_15395	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
HC341_15400	ENOG4105NWN	ApaG protein
HC341_15405	ENOG4105DDT	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP (By similarity)
HC341_15410	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
HC341_15420	ENOG4105C7Z	Conserved Protein
HC341_15430	ENOG4105C12	Phosphoribosylglycinamide synthetase
HC341_15435	ENOG4105DC1	bifunctional purine biosynthesis protein purh
HC341_15460	ENOG4105F0N	pyrophosphate phospho-hydrolase
HC341_15465	ENOG4107R15	K00850 6-phosphofructokinase 1 EC 2.7.1.11
HC341_15475	ENOG4105DFU	Cell wall formation (By similarity)
HC341_15480	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
HC341_15490	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
HC341_15495	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
HC341_15500	ENOG4105VCQ	rubredoxin
HC341_15510	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
HC341_15520	ENOG4107QZM	n-acetylglutamate synthase
HC341_15525	ENOG4105CWC	Acetylornithine deacetylase
HC341_15545	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
HC341_15555	ENOG4107X2D	transcriptional regulator, merr family
HC341_15560	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
HC341_15570	ENOG4105BZU	Histidine kinase
HC341_15575	ENOG4105EUJ	GTP cyclohydrolase i
HC341_15580	ENOG4105KKP	D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase
HC341_15595	ENOG4105C3N	Participates in control of cell volume in low-osmolarity conditions (By similarity)
HC341_15625	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
HC341_15630	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
HC341_15635	ENOG4105C34	Pseudouridine synthase
HC341_15640	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
HC341_15645	ENOG4108YZA	Nitrogen regulatory protein pii
HC341_15655	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
HC341_15660	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
HC341_15680	ENOG4107TUY	Histidine kinase
HC341_15685	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HC341_15705	ENOG4105BZU	Histidine kinase
HC341_15735	ENOG4108Z4V	iron-sulfur cluster assembly
HC341_15740	ENOG4108ZXC	Two component transcriptional regulator, luxr family
HC341_15745	ENOG4105BZU	Histidine kinase
HC341_15750	ENOG4105CEY	Amp-dependent synthetase and ligase
HC341_15760	ENOG4107YZX	Universal stress protein
HC341_15765	ENOG4105CSU	acyl-Coa dehydrogenase
HC341_15780	ENOG4107QX8	SPFH domain, Band 7 family protein
HC341_15810	ENOG4105VDM	plasmid maintenance system antidote protein, xre family
HC341_15815	ENOG41080ET	plasmid maintenance system killer protein
HC341_15830	ENOG4105C84	Histidine ammonia-lyase
HC341_15840	ENOG4105CEY	Amp-dependent synthetase and ligase
HC341_15865	ENOG4105DAY	polysaccharide export protein
HC341_15875	ENOG4105D75	Capsular exopolysaccharide family
HC341_15900	ENOG4105K64	Glycosyl transferase, family 2
HC341_15920	ENOG4105BZ1	(ABC) transporter
HC341_15950	ENOG4105K64	Glycosyl transferase, family 2
HC341_15955	ENOG4105K64	Glycosyl transferase, family 2
HC341_15990	ENOG4105CAQ	asparagine synthetase
HC341_15995	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HC341_16045	ENOG4107R8N	Glycosyl transferase, family 2
HC341_16065	ENOG4105E5H	Transposase
HC341_16080	ENOG4107R3N	Filamentation induced by cAMP protein fic
HC341_16090	ENOG4105CBS	Chea signal transduction histidine kinase
HC341_16095	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HC341_16115	ENOG4107QQG	Dehydrogenase
HC341_16125	ENOG4105C9M	aspartyl-trna synthetase
HC341_16130	ENOG4105BZU	Histidine kinase
HC341_16135	ENOG4105BZU	Histidine kinase
HC341_16155	ENOG4105E1F	short-chain dehydrogenase reductase
HC341_16180	ENOG4107QZF	nitrite reductase NADPH large subunit
HC341_16185	ENOG41089UC	methyltransferase, type 11
HC341_16195	ENOG4105EMN	RNA polymerase sigma factor
HC341_16200	ENOG41089UC	methyltransferase, type 11
HC341_16220	ENOG4105GNX	MltA-interacting MipA family protein
HC341_16235	ENOG4105CJ1	ABC, transporter
HC341_16245	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
HC341_16265	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
HC341_16320	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
HC341_16335	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
HC341_16340	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
HC341_16345	ENOG4105DTN	riboflavin biosynthesis protein ribF
HC341_16350	ENOG4105CJR	Integral membrane protein (MviN
HC341_16400	ENOG4107QP8	phosphohexose isomerase
HC341_16405	ENOG4105C3Y	UTP-glucose-1-phosphate uridylyltransferase
HC341_16410	ENOG4105BZU	Histidine kinase
HC341_16415	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HC341_16420	ENOG4107RIQ	Sulfate adenylate transferase
HC341_16430	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
HC341_16440	ENOG4105CKU	formyltetrahydrofolate synthetase
HC341_16445	ENOG4105ECQ	AraC Family Transcriptional Regulator
HC341_16455	ENOG4108UJD	30S ribosomal protein S9
HC341_16460	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
HC341_16470	ENOG4105FDS	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
HC341_16475	ENOG4108UKZ	OsmC family
HC341_16480	ENOG4107RYR	Transcriptional regulator, Crp Fnr family
HC341_16485	ENOG4105DK0	Indole-3-glycerol phosphate synthase
HC341_16490	ENOG4108I0Q	anthranilate phosphoribosyltransferase
HC341_16495	ENOG4105DDQ	anthranilate synthase
HC341_16500	ENOG4105CRQ	synthase (Component I)
HC341_16505	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
HC341_16510	ENOG4105DJV	ribulose-phosphate 3-epimerase
HC341_16520	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
HC341_16530	ENOG4105EC0	Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions (By similarity)
HC341_16535	ENOG4105C1Q	protoporphyrinogen oxidase
HC341_16545	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
HC341_16555	ENOG4105ERU	peptidase
HC341_16575	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
HC341_16590	ENOG410904N	short-chain dehydrogenase reductase
HC341_16595	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
HC341_16600	ENOG4105CD5	CoA-binding domain protein
HC341_16605	ENOG4107RHT	methyl-accepting chemotaxis sensory transducer with Pas Pac sensor
HC341_16615	ENOG4105C5I	Dehydrogenase
HC341_16620	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
HC341_16625	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
HC341_16635	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
HC341_16645	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
HC341_16650	ENOG4108IAB	Phoh family
HC341_16660	ENOG4108R1E	Serine threonine protein phosphatase 1
HC341_16680	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
HC341_16690	ENOG4105BZU	Histidine kinase
HC341_16700	ENOG4105D9I	Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6 (By similarity)
HC341_16715	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
HC341_16720	ENOG4105KAV	tspo and mbr like protein
HC341_16725	ENOG4108ZZ3	UPF0260 protein
HC341_16730	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
HC341_16745	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
HC341_16755	ENOG4108ZG0	Ompa motb domain protein
HC341_16760	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
HC341_16765	ENOG4107VFP	cytochrome oxidase assembly
HC341_16785	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
HC341_16795	ENOG4105BZ9	Cytochrome C oxidase, subunit I
HC341_16815	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
HC341_16820	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
HC341_16825	ENOG4105MJ2	Competence protein
HC341_16835	ENOG4105EMN	RNA polymerase sigma factor
HC341_16855	ENOG4105D8X	mechanosensitive ion channel
HC341_16865	ENOG4105C6K	Malic enzyme
HC341_16885	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
HC341_16905	ENOG4107T1C	Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate (By similarity)
HC341_16925	ENOG4105D0M	Protease HtpX homolog
HC341_16930	ENOG4105BZU	Histidine kinase
HC341_16935	ENOG4105E5G	Alpha beta hydrolase fold
HC341_16970	ENOG4105CS6	Rhs element vgr protein
HC341_17020	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
HC341_17025	ENOG4105K63	Thioredoxin
HC341_17035	ENOG4105GVR	general secretion pathway protein D
HC341_17040	ENOG4107QHF	type ii secretion system protein e
HC341_17045	ENOG4105D7Q	type ii secretion system
HC341_17050	ENOG4108VAU	general secretion pathway protein G
HC341_17055	ENOG4105VWV	general secretion pathway protein h
HC341_17065	ENOG4108WWZ	General secretion pathway protein J
HC341_17070	ENOG4108RTD	type II secretion system protein K
HC341_17090	ENOG4107RK2	ADP-ribose diphosphatase NudE
HC341_17095	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
HC341_17115	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
HC341_17130	ENOG4108Z7G	MaoC domain protein dehydratase
HC341_17135	ENOG4105CV6	ABC transporter, permease
HC341_17140	ENOG4108I0Y	(ABC) transporter
HC341_17145	ENOG4108UJV	acyl-CoA thioesterase i
HC341_17150	ENOG4105DH7	May be involved in recombination (By similarity)
HC341_17155	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
HC341_17160	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
HC341_17185	ENOG4105D1N	poly(r)-hydroxyalkanoic acid synthase, class
HC341_17195	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
HC341_17200	ENOG4105E98	transcriptional regulator DeoR family
HC341_17205	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
HC341_17215	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
HC341_17220	ENOG41067HS	methyltransferase
HC341_17235	ENOG4105C26	Dehydrogenase
HC341_17250	ENOG4105KMG	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes (By similarity)
HC341_17255	ENOG4105CEN	a g-specific adenine glycosylase
HC341_17275	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HC341_17280	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
HC341_17285	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
HC341_17290	ENOG4105CPC	Aldo Keto reductase
HC341_17300	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
HC341_17340	ENOG4105C3M	thioredoxin reductase
HC341_17350	ENOG4105CGK	Exodeoxyribonuclease III
HC341_17355	ENOG4105CHU	acetyl-coa acetyltransferase
HC341_17365	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
HC341_17370	ENOG4107QP2	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
HC341_17375	ENOG4107XM9	(LipO)protein
HC341_17380	ENOG4105E5G	Alpha beta hydrolase fold
HC341_17385	ENOG4105CTQ	phosphohexokinase
HC341_17395	ENOG4105CAS	nag kinase
HC341_17400	ENOG4107QKV	phosphomannomutase
HC341_17405	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
HC341_17410	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
HC341_17415	ENOG4105W5Q	DNA repair protein (RadC
HC341_17425	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HC341_17430	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
HC341_17435	ENOG4105CAK	Cell division ATP-binding protein ftsE
HC341_17440	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
HC341_17450	ENOG4105C1V	Peptidase, M16
HC341_17455	ENOG4106H78	methyltransferase
HC341_17460	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
HC341_17465	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
HC341_17485	ENOG4108T7K	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Increasing levels of c-di-GMP lead to decreased motility (By similarity)
HC341_17495	ENOG4108RRZ	Transcription elongation factor GreB
HC341_17510	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
HC341_17535	ENOG4105D58	Diguanylate phosphodiesterase
HC341_17540	ENOG4105W0E	50S ribosomal protein L33
HC341_17545	ENOG4105KDC	50s ribosomal protein l28
HC341_17550	ENOG4105VN1	Heat shock protein
HC341_17565	ENOG4105C0H	protease
HC341_17570	ENOG41067XB	TonB family
HC341_17575	ENOG4105M15	transport protein ExbD
HC341_17580	ENOG4109015	Biopolymer transport protein exbD tolR
HC341_17605	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
HC341_17610	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
HC341_17615	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
HC341_17620	ENOG4105DKP	glycosyl transferase, family 9
HC341_17625	ENOG4108W7E	Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position (By similarity)
HC341_17630	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
HC341_17635	ENOG4105D1S	lipid A biosynthesis
HC341_17685	ENOG4107XU6	Glycosyl transferase (Group 1
HC341_17690	ENOG4107TYR	Glycosyl Transferase
HC341_17700	ENOG4107RDJ	Sulfotransferase
HC341_17705	ENOG4105E2K	Glycosyl transferase (Group 1
HC341_17720	ENOG4105BZ1	(ABC) transporter
HC341_17730	ENOG4105CM2	brancheD-chain amino acid aminotransferase
HC341_17735	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
HC341_17740	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
HC341_17745	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
HC341_17750	ENOG4105VF7	tolerance protein
HC341_17755	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
HC341_17760	ENOG4107QX9	Thiol disulfide interChange protein
HC341_17765	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
HC341_17770	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
HC341_17775	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
HC341_17795	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
HC341_17805	ENOG4105F8J	Adenylate Guanylate cyclase
HC341_17810	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
HC341_17825	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
HC341_17830	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
HC341_17835	ENOG4105VCC	30S ribosomal protein S21
HC341_17840	ENOG4105KTH	gatB Yqey
HC341_17845	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
HC341_17850	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
HC341_17910	ENOG4105BZU	Histidine kinase
HC341_17915	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
HC341_17935	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
HC341_17960	ENOG4108JQ7	(ABC) transporter
HC341_17965	ENOG4105C3U	ABC transporter
HC341_17990	ENOG41090R7	Ferric uptake
HC341_17995	ENOG4105CN9	Peptidase m42 family protein
HC341_18015	ENOG4107RN6	Monooxygenase
HC341_18020	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
HC341_18045	ENOG4105EKQ	RNA-directed DNA polymerase
HC341_18050	ENOG4105EKQ	RNA-directed DNA polymerase
HC341_18055	ENOG4106VK6	Flagellar motor protein
HC341_18075	ENOG4108YZA	Nitrogen regulatory protein pii
HC341_18085	ENOG4105C0P	Mg chelatase subunit ChlI
HC341_18090	ENOG4108IV0	ABC, transporter
HC341_18095	ENOG4105C0Z	ABC transporter
HC341_18105	ENOG4105C32	Amino acid ABC transporter (Permease)
HC341_18110	ENOG4107TSX	ABC branched chain amino acid family transporter periplasmic ligand binding protein
HC341_18115	ENOG4105E8T	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG (By similarity)
HC341_18120	ENOG4108YH3	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HC341_18125	ENOG4105MMR	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly (By similarity)
HC341_18130	ENOG4105CQM	Urea amidohydrolase subunit alpha
HC341_18135	ENOG4105KI2	Urea amidohydrolase subunit beta
HC341_18140	ENOG4108YZ9	Urea amidohydrolase subunit gamma
HC341_18145	ENOG4108M9X	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter (By similarity)
HC341_18165	ENOG4105EA8	2-Nitropropane dioxygenase
HC341_18175	ENOG4105CEY	Amp-dependent synthetase and ligase
HC341_18195	ENOG4105C1G	acyl-Coa dehydrogenase
HC341_18205	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
HC341_18210	ENOG4105CH2	amidohydrolase
HC341_18220	ENOG4105CH5	extracellular solute-binding protein, family 7
HC341_18265	ENOG4105CC0	LysR family Transcriptional regulator
HC341_18270	ENOG4105CK7	Sodium proline symporter
HC341_18275	ENOG4105BZU	Histidine kinase
HC341_18345	ENOG4105DIK	(ABC) transporter
HC341_18350	ENOG4105CC5	ABC transporter
HC341_18355	ENOG4105DSE	periplasmic solute binding protein
HC341_18360	ENOG4105CKI	cobalamin synthesis protein
HC341_18370	ENOG4105CKI	cobalamin synthesis protein
HC341_18410	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
HC341_18425	ENOG4105DVK	Precorrin-2 c20-methyltransferase
HC341_18430	ENOG41081F0	Precorrin-8x methylmutase
HC341_18440	ENOG4105E3A	(ABC) transporter
HC341_18445	ENOG4105DA5	(ABC) transporter
HC341_18455	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
HC341_18475	ENOG4105F2Z	3-oxoadipate enol-lactonase
HC341_18480	ENOG4105E39	Enoyl-CoA hydratase
HC341_18490	ENOG4105CC9	acyl-Coa dehydrogenase
HC341_18530	ENOG4105F9F	transposase
HC341_18550	ENOG4105BZU	Histidine kinase
HC341_18560	ENOG4108Z33	Thiol disulfide Interchange Protein
HC341_18565	ENOG4105CRE	cytochrome C
HC341_18570	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
HC341_18575	ENOG4106RE7	Cytochrome
HC341_18580	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
HC341_18585	ENOG4105C2M	dna polymerase I
HC341_18595	ENOG4108URH	decarboxylase
HC341_18605	ENOG4105C4R	Atp-dependent dna helicase
HC341_18610	ENOG4105C5Q	Transcriptional regulator
HC341_18615	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
HC341_18620	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
HC341_18625	ENOG4107YZX	Universal stress protein
HC341_18630	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
HC341_18635	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
HC341_18640	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
HC341_18650	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
HC341_18655	ENOG4107S15	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HC341_18660	ENOG4107Z6K	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HC341_18665	ENOG4105KY6	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
HC341_18670	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
HC341_18680	ENOG4105FA0	parb-like partition protein
HC341_18685	ENOG4107QJE	Chromosome Partitioning Protein
HC341_18690	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
HC341_18695	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
HC341_18705	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
HC341_18710	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
HC341_18715	ENOG4105NVJ	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
HC341_18720	ENOG4105VG0	50S ribosomal protein l34