locus-tag	class	description
DLM_0002	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DLM_0009	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DLM_0010	COG2084	Dehydrogenase
DLM_0011	COG3813	Protein conserved in bacteria
DLM_0016	COG1561	YicC-like family, N-terminal region
DLM_0017	COG0515	serine threonine protein kinase
DLM_0017	COG1357	PFAM Pentapeptide repeats (8 copies)
DLM_0018	COG0631	protein serine/threonine phosphatase activity
DLM_0019	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DLM_0020	COG3591	Belongs to the peptidase S1B family
DLM_0022	COG2205	protein histidine kinase activity
DLM_0023	COG0745	RESPONSE REGULATOR receiver
DLM_0024	COG0840	transmembrane signaling receptor activity
DLM_0027	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DLM_0031	COG0109	protoheme IX farnesyltransferase activity
DLM_0033	COG3501	Rhs element vgr protein
DLM_0034	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DLM_0035	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DLM_0036	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DLM_0041	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DLM_0042	COG0306	phosphate transporter
DLM_0043	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DLM_0046	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
DLM_0047	COG0149	triose-phosphate isomerase activity
DLM_0049	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DLM_0050	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DLM_0051	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DLM_0052	COG0649	NAD binding
DLM_0053	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DLM_0055	COG1034	ATP synthesis coupled electron transport
DLM_0056	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DLM_0057	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DLM_0059	COG0713	ATP synthesis coupled electron transport
DLM_0062	COG1007	ATP synthesis coupled electron transport
DLM_0064	COG1560	Kdo2-lipid A biosynthetic process
DLM_0066	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DLM_0067	COG0004	ammonium transporteR
DLM_0068	COG0347	Belongs to the P(II) protein family
DLM_0070	COG0606	chelatase, subunit chli
DLM_0072	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DLM_0076	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DLM_0078	COG1555	photosystem II stabilization
DLM_0078	COG1596	polysaccharide export
DLM_0079	COG0415	Belongs to the DNA photolyase family
DLM_0084	COG0237	dephospho-CoA kinase activity
DLM_0085	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
DLM_0086	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DLM_0087	COG0860	N-Acetylmuramoyl-L-alanine amidase
DLM_0088	COG0802	atpase or kinase
DLM_0091	COG2030	dehydratase
DLM_0094	COG1960	acyl-CoA dehydrogenase activity
DLM_0100	COG1534	Rna-binding protein
DLM_0101	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DLM_0102	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DLM_0104	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DLM_0105	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DLM_0106	COG0586	Pfam SNARE associated Golgi protein
DLM_0111	COG0386	Belongs to the glutathione peroxidase family
DLM_0112	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DLM_0115	COG0543	2 iron, 2 sulfur cluster binding
DLM_0115	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DLM_0118	COG2235	arginine
DLM_0119	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DLM_0123	COG1695	Transcriptional regulator
DLM_0125	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DLM_0126	COG2252	PERMEase
DLM_0127	COG0194	GDP metabolic process
DLM_0128	COG1758	RNA polymerase activity
DLM_0129	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DLM_0131	COG2022	thiamine diphosphate biosynthetic process
DLM_0132	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DLM_0137	COG1301	dicarboxylic acid transport
DLM_0141	COG0840	transmembrane signaling receptor activity
DLM_0143	COG0583	DNA-binding transcription factor activity
DLM_0144	COG0019	diaminopimelate decarboxylase activity
DLM_0147	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DLM_0151	COG0583	DNA-binding transcription factor activity
DLM_0155	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DLM_0156	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DLM_0159	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DLM_0161	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DLM_0165	COG2264	protein methyltransferase activity
DLM_0166	COG0439	Biotin carboxylase
DLM_0167	COG0511	ligase activity, forming carbon-carbon bonds
DLM_0168	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DLM_0170	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DLM_0172	COG2226	methyltransferase
DLM_0175	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DLM_0178	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_0179	COG2610	gluconate transmembrane transporter activity
DLM_0180	COG3604	Transcriptional regulator
DLM_0183	COG0436	Aminotransferase
DLM_0190	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DLM_0191	COG0513	Belongs to the DEAD box helicase family
DLM_0193	COG1139	Iron-sulfur cluster binding protein
DLM_0194	COG0247	lactate metabolic process
DLM_0199	COG3276	selenocysteine insertion sequence binding
DLM_0200	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
DLM_0204	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DLM_0206	COG2201	protein-glutamate methylesterase activity
DLM_0207	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DLM_0208	COG0835	chemotaxis
DLM_0211	COG2198	Histidine kinase
DLM_0211	COG0643	Histidine kinase
DLM_0216	COG2864	formate dehydrogenase
DLM_0217	COG0437	4 iron, 4 sulfur cluster binding
DLM_0219	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DLM_0221	COG0527	aspartate kinase activity
DLM_0226	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DLM_0229	COG0488	(ABC) transporter
DLM_0232	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
DLM_0233	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DLM_0233	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DLM_0234	COG0793	Belongs to the peptidase S41A family
DLM_0235	COG4942	peptidase
DLM_0236	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DLM_0237	COG0640	Transcriptional regulator
DLM_0240	COG0811	peptide transport
DLM_0241	COG0848	biopolymer transport protein
DLM_0243	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DLM_0244	COG0563	adenylate kinase activity
DLM_0245	COG1272	protein, Hemolysin III
DLM_0246	COG3437	response regulator, receiver
DLM_0246	COG0784	Response regulator, receiver
DLM_0247	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_0247	COG4191	Histidine kinase
DLM_0249	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DLM_0249	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DLM_0251	COG1660	Displays ATPase and GTPase activities
DLM_0252	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DLM_0254	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DLM_0255	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DLM_0256	COG1137	ATPase activity
DLM_0257	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DLM_0259	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DLM_0264	COG2957	Belongs to the agmatine deiminase family
DLM_0266	COG0154	amidase activity
DLM_0269	COG0446	pyridine nucleotide-disulphide oxidoreductase
DLM_0269	COG1902	pentaerythritol trinitrate reductase activity
DLM_0271	COG0667	Aldo Keto reductase
DLM_0274	COG0330	HflC and HflK could
DLM_0275	COG0330	HflC and HflK could
DLM_0276	COG1914	H( )-stimulated, divalent metal cation uptake system
DLM_0277	COG0861	Integral membrane protein TerC family
DLM_0280	COG3842	ATPase activity
DLM_0284	COG2188	Transcriptional regulator
DLM_0287	COG0252	asparaginase activity
DLM_0292	COG0613	PHP domain protein
DLM_0293	COG0009	L-threonylcarbamoyladenylate synthase
DLM_0294	COG1994	Peptidase M50
DLM_0295	COG0180	Tryptophanyl-tRNA synthetase
DLM_0297	COG0583	DNA-binding transcription factor activity
DLM_0298	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DLM_0299	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DLM_0300	COG1187	pseudouridine synthase activity
DLM_0304	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DLM_0305	COG0583	DNA-binding transcription factor activity
DLM_0306	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DLM_0308	COG0850	regulation of cytokinetic process
DLM_0312	COG0583	DNA-binding transcription factor activity
DLM_0314	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DLM_0315	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
DLM_0320	COG1199	ATP-dependent helicase activity
DLM_0320	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DLM_0321	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DLM_0322	COG1191	sigma factor activity
DLM_0325	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DLM_0326	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DLM_0327	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DLM_0330	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DLM_0331	COG0402	S-adenosylhomocysteine deaminase activity
DLM_0334	COG2963	transposase activity
DLM_0335	COG2801	Transposase and inactivated derivatives
DLM_0344	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DLM_0346	COG0039	L-malate dehydrogenase activity
DLM_0347	COG2188	Transcriptional regulator
DLM_0351	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DLM_0352	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DLM_0355	COG0567	Dehydrogenase, E1 component
DLM_0356	COG0508	dehydrogenase complex catalyzes the overall conversion of
DLM_0358	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DLM_0359	COG0045	succinate-CoA ligase (ADP-forming) activity
DLM_0363	COG0583	DNA-binding transcription factor activity
DLM_0364	COG1380	Effector of murein hydrolase LrgA
DLM_0365	COG1346	cytolysis
DLM_0367	COG1607	acyl-coa hydrolase
DLM_0368	COG0564	pseudouridine synthase activity
DLM_0371	COG0463	Glycosyl transferase, family 2
DLM_0372	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
DLM_0373	COG3104	oligopeptide transport
DLM_0375	COG3033	Beta-eliminating lyase
DLM_0382	COG3278	Belongs to the heme-copper respiratory oxidase family
DLM_0384	COG0308	aminopeptidase N
DLM_0387	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DLM_0390	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DLM_0392	COG2169	Transcriptional regulator
DLM_0392	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DLM_0395	COG0310	cobalt ion transport
DLM_0396	COG1930	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import
DLM_0398	COG1122	ATPase activity
DLM_0417	COG0436	Aminotransferase
DLM_0418	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DLM_0420	COG0516	GMP reductase activity
DLM_0423	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DLM_0424	COG0489	protein tyrosine kinase activity
DLM_0426	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DLM_0426	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DLM_0430	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DLM_0431	COG3022	response to hydroperoxide
DLM_0433	COG1490	D-aminoacyl-tRNA deacylase activity
DLM_0434	COG0741	lytic transglycosylase activity
DLM_0434	COG1388	LysM domain
DLM_0435	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DLM_0436	COG2226	methyltransferase
DLM_0437	COG0328	RNA-DNA hybrid ribonuclease activity
DLM_0439	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DLM_0440	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DLM_0441	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DLM_0442	COG0704	Plays a role in the regulation of phosphate uptake
DLM_0443	COG0248	Ppx GppA phosphatase
DLM_0444	COG0598	Magnesium transport protein CorA
DLM_0449	COG0765	amino acid transport
DLM_0450	COG0765	amino acid transport
DLM_0451	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_0452	COG3639	organic phosphonate transmembrane transporter activity
DLM_0454	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
DLM_0455	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DLM_0456	COG0129	dihydroxy-acid dehydratase activity
DLM_0457	COG0625	glutathione transferase activity
DLM_0460	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DLM_0461	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DLM_0462	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DLM_0462	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DLM_0464	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DLM_0471	COG0322	excinuclease ABC activity
DLM_0472	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DLM_0479	COG3188	usher protein
DLM_0481	COG3539	Fimbrial protein
DLM_0484	COG1448	Aminotransferase
DLM_0487	COG1929	Belongs to the glycerate kinase type-1 family
DLM_0488	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DLM_0491	COG3012	SEC-C Motif Domain Protein
DLM_0493	COG0717	Belongs to the dCTP deaminase family
DLM_0495	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DLM_0497	COG3384	dioxygenase
DLM_0500	COG2974	May be involved in recombination
DLM_0506	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_0509	COG1538	Outer membrane efflux protein
DLM_0513	COG1309	transcriptional regulator
DLM_0515	COG0583	DNA-binding transcription factor activity
DLM_0516	COG1979	alcohol dehydrogenase
DLM_0517	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_0518	COG0702	epimerase
DLM_0520	COG0656	L-ascorbic acid biosynthetic process
DLM_0522	COG0477	Major facilitator Superfamily
DLM_0523	COG4221	oxidoreductase activity
DLM_0524	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_0526	COG1733	regulation of RNA biosynthetic process
DLM_0528	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DLM_0529	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLM_0534	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DLM_0536	COG3237	CsbD-like
DLM_0542	COG0583	DNA-binding transcription factor activity
DLM_0543	COG1047	Peptidyl-prolyl cis-trans
DLM_0544	COG1522	sequence-specific DNA binding
DLM_0546	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DLM_0547	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLM_0551	COG0673	inositol 2-dehydrogenase activity
DLM_0552	COG0673	inositol 2-dehydrogenase activity
DLM_0554	COG3962	Belongs to the TPP enzyme family
DLM_0557	COG1129	ABC transporter
DLM_0558	COG1172	Belongs to the binding-protein-dependent transport system permease family
DLM_0562	COG3718	enzyme involved in inositol metabolism
DLM_0565	COG0105	UTP biosynthetic process
DLM_0566	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DLM_0568	COG1426	Protein conserved in bacteria
DLM_0569	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DLM_0570	COG0124	histidyl-tRNA synthetase
DLM_0573	COG1160	GTP binding
DLM_0574	COG1923	regulation of RNA biosynthetic process
DLM_0575	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DLM_0576	COG0330	HflC and HflK could
DLM_0577	COG0330	HflC and HflK could
DLM_0578	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DLM_0579	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DLM_0580	COG0673	inositol 2-dehydrogenase activity
DLM_0581	COG4702	Belongs to the UPF0303 family
DLM_0582	COG1858	cytochrome C peroxidase
DLM_0584	COG0477	Major facilitator Superfamily
DLM_0588	COG0557	exoribonuclease II activity
DLM_0594	COG2205	protein histidine kinase activity
DLM_0596	COG2204	response regulator
DLM_0599	COG4230	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DLM_0599	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
DLM_0599	COG0506	proline dehydrogenase activity
DLM_0604	COG2205	protein histidine kinase activity
DLM_0604	COG2198	Histidine kinase
DLM_0604	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_0604	COG0784	Response regulator, receiver
DLM_0605	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DLM_0606	COG1960	acyl-CoA dehydrogenase activity
DLM_0611	COG3971	2-oxopent-4-enoate hydratase activity
DLM_0613	COG2814	Major facilitator Superfamily
DLM_0615	COG3384	dioxygenase
DLM_0616	COG1012	belongs to the aldehyde dehydrogenase family
DLM_0620	COG2207	Transcriptional regulator
DLM_0622	COG1012	belongs to the aldehyde dehydrogenase family
DLM_0625	COG1113	amino acid transport
DLM_0627	COG1846	Transcriptional regulator
DLM_0629	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_0633	COG4166	transmembrane transport
DLM_0634	COG4174	ABC transporter (Permease)
DLM_0635	COG4239	(ABC) transporter, permease
DLM_0636	COG4172	Belongs to the ABC transporter superfamily
DLM_0638	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DLM_0641	COG0745	RESPONSE REGULATOR receiver
DLM_0641	COG3706	GGDEF domain
DLM_0646	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DLM_0647	COG0534	Mate efflux family protein
DLM_0650	COG0617	tRNA 3'-terminal CCA addition
DLM_0653	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DLM_0654	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DLM_0655	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DLM_0657	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DLM_0658	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DLM_0659	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DLM_0660	COG4658	electron transport chain
DLM_0662	COG2878	Part of a membrane complex involved in electron transport
DLM_0666	COG3781	membrane
DLM_0667	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DLM_0669	COG3162	membrane
DLM_0670	COG0583	DNA-binding transcription factor activity
DLM_0672	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DLM_0673	COG4948	Mandelate Racemase Muconate Lactonizing
DLM_0674	COG1063	alcohol dehydrogenase
DLM_0675	COG0477	Major facilitator Superfamily
DLM_0676	COG0246	Mannitol dehydrogenase
DLM_0677	COG1802	Transcriptional regulator
DLM_0678	COG1620	l-lactate permease
DLM_0679	COG0840	transmembrane signaling receptor activity
DLM_0680	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DLM_0684	COG0659	secondary active sulfate transmembrane transporter activity
DLM_0685	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DLM_0686	COG1032	radical SAM domain protein
DLM_0689	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DLM_0690	COG0205	6-phosphofructokinase activity
DLM_0691	COG0215	cysteine-tRNA ligase activity
DLM_0692	COG0254	rRNA binding
DLM_0695	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DLM_0699	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DLM_0700	COG1960	acyl-CoA dehydrogenase activity
DLM_0702	COG0318	PFAM AMP-dependent synthetase and ligase
DLM_0703	COG3012	SEC-C Motif Domain Protein
DLM_0703	COG3318	Belongs to the UPF0149 family
DLM_0705	COG4948	Mandelate Racemase Muconate Lactonizing
DLM_0706	COG3254	rhamnose metabolic process
DLM_0707	COG3618	amidohydrolase
DLM_0711	COG1012	belongs to the aldehyde dehydrogenase family
DLM_0712	COG1960	acyl-CoA dehydrogenase activity
DLM_0716	COG2766	serine protein kinase
DLM_0717	COG2718	Belongs to the UPF0229 family
DLM_0718	COG2719	SpoVR family
DLM_0719	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DLM_0720	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DLM_0722	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DLM_0723	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DLM_0725	COG0167	dihydroorotate dehydrogenase activity
DLM_0727	COG1360	Flagellar Motor Protein
DLM_0730	COG0546	phosphoglycolate phosphatase activity
DLM_0732	COG1530	ribonuclease E activity
DLM_0734	COG0583	DNA-binding transcription factor activity
DLM_0735	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DLM_0736	COG3842	ATPase activity
DLM_0737	COG1176	ABC-type spermidine putrescine transport system, permease component I
DLM_0738	COG1177	transmembrane transport
DLM_0739	COG1012	belongs to the aldehyde dehydrogenase family
DLM_0746	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DLM_0748	COG1376	ErfK ybiS ycfS ynhG family protein
DLM_0749	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DLM_0750	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DLM_0755	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DLM_0770	COG0776	regulation of translation
DLM_0774	COG3023	N-Acetylmuramoyl-L-alanine amidase
DLM_0781	COG4373	Mu-like prophage FluMu protein gp28
DLM_0782	COG4383	Mu-like prophage protein gp29
DLM_0789	COG4387	Mu-like prophage protein GP36
DLM_0806	COG1562	ergosterol biosynthetic process
DLM_0808	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DLM_0809	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_0812	COG1595	DNA-templated transcription, initiation
DLM_0817	COG0791	NLP P60 protein
DLM_0820	COG1136	(ABC) transporter
DLM_0821	COG3264	Mechanosensitive ion channel
DLM_0821	COG1511	domain protein
DLM_0822	COG4566	intracellular signal transduction
DLM_0825	COG0671	phosphoesterase, PA-phosphatase related
DLM_0828	COG3568	Endonuclease Exonuclease Phosphatase
DLM_0829	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DLM_0830	COG2011	ABC-type metal ion transport system permease component
DLM_0831	COG1464	Belongs to the NlpA lipoprotein family
DLM_0833	COG1418	mRNA catabolic process
DLM_0834	COG2313	pseudouridylate synthase activity
DLM_0835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DLM_0835	COG1522	sequence-specific DNA binding
DLM_0837	COG4178	(ABC) transporter
DLM_0840	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DLM_0841	COG2990	Protein conserved in bacteria
DLM_0843	COG0280	phosphate acetyltransferase
DLM_0843	COG0281	malic enzyme
DLM_0848	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DLM_0855	COG4191	Histidine kinase
DLM_0859	COG4215	(ABC) transporter
DLM_0862	COG2902	Dehydrogenase
DLM_0864	COG0697	spore germination
DLM_0867	COG2963	transposase activity
DLM_0868	COG2801	Transposase and inactivated derivatives
DLM_0877	COG4383	Mu-like prophage protein gp29
DLM_0878	COG4373	Mu-like prophage FluMu protein gp28
DLM_0885	COG3023	N-Acetylmuramoyl-L-alanine amidase
DLM_0899	COG2801	Transposase and inactivated derivatives
DLM_0906	COG3179	chitinase
DLM_0912	COG1960	acyl-CoA dehydrogenase activity
DLM_0916	COG1858	cytochrome C peroxidase
DLM_0918	COG0488	(ABC) transporter
DLM_0924	COG1881	PFAM PEBP family protein
DLM_0926	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_0927	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_0932	COG4774	siderophore transport
DLM_0933	COG2819	hydrolase of the alpha beta superfamily
DLM_0937	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DLM_0938	COG0745	RESPONSE REGULATOR receiver
DLM_0939	COG0835	chemotaxis
DLM_0939	COG0784	Response regulator, receiver
DLM_0940	COG0784	Response regulator, receiver
DLM_0940	COG0835	chemotaxis
DLM_0943	COG4302	ethanolamine ammonia-lyase activity
DLM_0944	COG4303	Ethanolamine ammonia lyase large subunit
DLM_0945	COG0531	amino acid
DLM_0947	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DLM_0955	COG1686	Belongs to the peptidase S11 family
DLM_0956	COG0556	nucleotide-excision repair
DLM_0958	COG0583	DNA-binding transcription factor activity
DLM_0961	COG0840	transmembrane signaling receptor activity
DLM_0964	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
DLM_0965	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DLM_0966	COG2201	protein-glutamate methylesterase activity
DLM_0967	COG2204	response regulator
DLM_0968	COG1677	Flagellar hook-basal body complex protein FliE
DLM_0969	COG1766	The M ring may be actively involved in energy transduction
DLM_0970	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DLM_0972	COG1157	protein secretion by the type III secretion system
DLM_0974	COG3842	ATPase activity
DLM_0980	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DLM_0984	COG1987	bacterial-type flagellum assembly
DLM_0985	COG1684	flagellar biosynthetic protein fliR
DLM_0986	COG0217	transcriptional regulatory protein
DLM_0987	COG0006	proline dipeptidase activity
DLM_0988	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DLM_0989	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DLM_0990	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DLM_0993	COG0686	Belongs to the AlaDH PNT family
DLM_0996	COG0583	DNA-binding transcription factor activity
DLM_0997	COG0501	Belongs to the peptidase M48B family
DLM_0999	COG0038	chloride channel
DLM_1000	COG1012	belongs to the aldehyde dehydrogenase family
DLM_1001	COG2223	nitrite transmembrane transporter activity
DLM_1002	COG4948	Mandelate Racemase Muconate Lactonizing
DLM_1006	COG2134	cdp-diacylglycerol pyrophosphatase
DLM_1007	COG2814	Major facilitator Superfamily
DLM_1014	COG0583	DNA-binding transcription factor activity
DLM_1015	COG1349	DNA-binding transcription factor activity
DLM_1019	COG0183	Belongs to the thiolase family
DLM_1021	COG2271	Major facilitator Superfamily
DLM_1022	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DLM_1024	COG2356	endonuclease I
DLM_1027	COG1181	Belongs to the D-alanine--D-alanine ligase family
DLM_1028	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DLM_1029	COG0745	RESPONSE REGULATOR receiver
DLM_1030	COG2205	protein histidine kinase activity
DLM_1031	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DLM_1032	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DLM_1033	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DLM_1036	COG0730	response to heat
DLM_1038	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DLM_1038	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_1039	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
DLM_1042	COG0542	response to heat
DLM_1049	COG0791	NLP P60 protein
DLM_1053	COG0285	dihydrofolate synthase activity
DLM_1054	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
DLM_1055	COG1286	toxin biosynthetic process
DLM_1059	COG1960	acyl-CoA dehydrogenase activity
DLM_1063	COG1024	Enoyl-CoA hydratase
DLM_1063	COG1250	3-hydroxyacyl-CoA dehydrogenase
DLM_1064	COG0183	Belongs to the thiolase family
DLM_1066	COG1752	Esterase of the alpha-beta hydrolase superfamily
DLM_1067	COG0134	indole-3-glycerol-phosphate synthase activity
DLM_1068	COG0429	hydrolase of the alpha beta-hydrolase fold
DLM_1069	COG0521	Mo-molybdopterin cofactor biosynthetic process
DLM_1070	COG3028	Belongs to the UPF0307 family
DLM_1071	COG0312	modulator of DNA gyrase
DLM_1073	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DLM_1086	COG0825	malonyl-CoA metabolic process
DLM_1087	COG0037	tRNA processing
DLM_1090	COG0544	peptidyl-prolyl cis-trans isomerase activity
DLM_1091	COG0740	serine-type endopeptidase activity
DLM_1092	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DLM_1093	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DLM_1097	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DLM_1098	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DLM_1099	COG2081	HI0933 family
DLM_1100	COG0305	Participates in initiation and elongation during chromosome replication
DLM_1101	COG3411	Ferredoxin
DLM_1103	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DLM_1104	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DLM_1105	COG0024	Methionine aminopeptidase
DLM_1108	COG1199	ATP-dependent helicase activity
DLM_1110	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DLM_1111	COG0137	argininosuccinate synthase activity
DLM_1113	COG1280	lysine exporter protein (LysE YggA)
DLM_1115	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DLM_1116	COG1454	alcohol dehydrogenase
DLM_1119	COG0837	glucose binding
DLM_1119	COG1737	Transcriptional regulator
DLM_1120	COG1666	GTP binding
DLM_1121	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DLM_1123	COG1012	belongs to the aldehyde dehydrogenase family
DLM_1125	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DLM_1126	COG0174	glutamine synthetase
DLM_1129	COG1360	Flagellar Motor Protein
DLM_1132	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DLM_1135	COG0617	tRNA 3'-terminal CCA addition
DLM_1137	COG1196	nuclear chromosome segregation
DLM_1137	COG0739	heme binding
DLM_1137	COG0741	lytic transglycosylase activity
DLM_1140	COG0546	phosphoglycolate phosphatase activity
DLM_1141	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_1143	COG2967	ApaG domain
DLM_1145	COG5265	(ABC) transporter
DLM_1146	COG5002	protein histidine kinase activity
DLM_1146	COG5001	Diguanylate cyclase
DLM_1148	COG2195	Cleaves the N-terminal amino acid of tripeptides
DLM_1149	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DLM_1150	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DLM_1155	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DLM_1156	COG0733	neurotransmitter:sodium symporter activity
DLM_1157	COG2818	Glycosylase
DLM_1158	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DLM_1159	COG2833	Protein of unknown function (DUF455)
DLM_1165	COG1176	ABC-type spermidine putrescine transport system, permease component I
DLM_1166	COG1177	transmembrane transport
DLM_1169	COG0018	arginyl-trna synthetase
DLM_1170	COG0006	proline dipeptidase activity
DLM_1171	COG0513	Belongs to the DEAD box helicase family
DLM_1172	COG3622	Belongs to the hyi family
DLM_1174	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DLM_1179	COG0735	belongs to the Fur family
DLM_1180	COG0523	cobalamin synthesis protein
DLM_1182	COG1121	(ABC) transporter
DLM_1183	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DLM_1184	COG0803	Belongs to the bacterial solute-binding protein 9 family
DLM_1186	COG1024	Enoyl-CoA hydratase
DLM_1187	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DLM_1188	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DLM_1190	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DLM_1192	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DLM_1192	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DLM_1204	COG0667	Aldo Keto reductase
DLM_1205	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_1208	COG0583	DNA-binding transcription factor activity
DLM_1209	COG1979	alcohol dehydrogenase
DLM_1210	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_1211	COG0702	epimerase
DLM_1213	COG0656	L-ascorbic acid biosynthetic process
DLM_1214	COG0183	Belongs to the thiolase family
DLM_1216	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_1217	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_1220	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DLM_1221	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLM_1226	COG1764	response to oxidative stress
DLM_1232	COG0840	transmembrane signaling receptor activity
DLM_1234	COG2201	protein-glutamate methylesterase activity
DLM_1236	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DLM_1237	COG0745	RESPONSE REGULATOR receiver
DLM_1238	COG0643	Histidine kinase
DLM_1238	COG2198	Histidine kinase
DLM_1240	COG0745	RESPONSE REGULATOR receiver
DLM_1241	COG0840	transmembrane signaling receptor activity
DLM_1243	COG5002	protein histidine kinase activity
DLM_1243	COG0784	Response regulator, receiver
DLM_1243	COG2205	protein histidine kinase activity
DLM_1252	COG2801	Transposase and inactivated derivatives
DLM_1253	COG2963	transposase activity
DLM_1265	COG4397	Mu-like prophage major head subunit gpT
DLM_1269	COG2369	cell adhesion
DLM_1270	COG4383	Mu-like prophage protein gp29
DLM_1281	COG0776	regulation of translation
DLM_1291	COG3423	Transcriptional regulator
DLM_1294	COG2801	Transposase and inactivated derivatives
DLM_1295	COG2963	transposase activity
DLM_1299	COG2963	transposase activity
DLM_1302	COG3501	Rhs element vgr protein
DLM_1314	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DLM_1321	COG2169	Transcriptional regulator
DLM_1321	COG1917	Cupin 2, conserved barrel domain protein
DLM_1325	COG2205	protein histidine kinase activity
DLM_1326	COG0745	RESPONSE REGULATOR receiver
DLM_1337	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DLM_1340	COG3706	GGDEF domain
DLM_1340	COG0745	RESPONSE REGULATOR receiver
DLM_1343	COG0640	Transcriptional regulator
DLM_1348	COG2814	Major facilitator Superfamily
DLM_1353	COG1764	response to oxidative stress
DLM_1356	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DLM_1358	COG0840	transmembrane signaling receptor activity
DLM_1359	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
DLM_1360	COG4266	Belongs to the allantoicase family
DLM_1361	COG4598	ABC transporter
DLM_1363	COG0765	amino acid transport
DLM_1365	COG2188	Transcriptional regulator
DLM_1368	COG0559	Belongs to the binding-protein-dependent transport system permease family
DLM_1370	COG0411	ABC transporter
DLM_1375	COG0804	urea catabolic process
DLM_1376	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
DLM_1377	COG0830	nickel cation binding
DLM_1378	COG0454	-acetyltransferase
DLM_1379	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DLM_1381	COG0784	Response regulator, receiver
DLM_1381	COG2198	Histidine kinase
DLM_1381	COG5002	protein histidine kinase activity
DLM_1382	COG1126	abc transporter atp-binding protein
DLM_1384	COG2072	flavoprotein involved in K transport
DLM_1386	COG0559	Belongs to the binding-protein-dependent transport system permease family
DLM_1388	COG0411	ABC transporter
DLM_1392	COG0601	transmembrane transport
DLM_1394	COG0444	Belongs to the ABC transporter superfamily
DLM_1395	COG4608	Belongs to the ABC transporter superfamily
DLM_1397	COG2814	Major facilitator Superfamily
DLM_1408	COG0583	DNA-binding transcription factor activity
DLM_1409	COG2814	Major facilitator Superfamily
DLM_1412	COG1760	l-serine dehydratase
DLM_1415	COG0583	DNA-binding transcription factor activity
DLM_1416	COG2040	homocysteine
DLM_1418	COG4521	taurine ABC transporter
DLM_1419	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DLM_1420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DLM_1421	COG2175	clavaminate synthase activity
DLM_1422	COG0513	Belongs to the DEAD box helicase family
DLM_1423	COG0840	transmembrane signaling receptor activity
DLM_1426	COG0583	DNA-binding transcription factor activity
DLM_1428	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_1431	COG0688	phosphatidylethanolamine metabolic process
DLM_1432	COG3706	GGDEF domain
DLM_1440	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DLM_1442	COG0481	GTPase activity
DLM_1445	COG0571	ribonuclease III activity
DLM_1446	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DLM_1448	COG1381	Involved in DNA repair and RecF pathway recombination
DLM_1449	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DLM_1450	COG0736	holo-[acyl-carrier-protein] synthase activity
DLM_1451	COG1472	Belongs to the glycosyl hydrolase 3 family
DLM_1453	COG2770	Histidine kinase
DLM_1453	COG3437	response regulator, receiver
DLM_1454	COG1643	Atp-dependent helicase
DLM_1459	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DLM_1472	COG1619	proteins homologs of microcin C7 resistance protein MccF
DLM_1474	COG0175	sulfate reduction
DLM_1475	COG2895	sulfate adenylyltransferase (ATP) activity
DLM_1478	COG0523	cobalamin synthesis protein
DLM_1479	COG2431	L-lysine efflux transmembrane transporter activity
DLM_1484	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DLM_1485	COG0564	pseudouridine synthase activity
DLM_1494	COG0840	transmembrane signaling receptor activity
DLM_1500	COG1294	oxidase, subunit
DLM_1501	COG0583	DNA-binding transcription factor activity
DLM_1502	COG4221	oxidoreductase activity
DLM_1509	COG2423	ornithine cyclodeaminase activity
DLM_1510	COG2186	Transcriptional regulator
DLM_1517	COG2011	ABC-type metal ion transport system permease component
DLM_1522	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_1528	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DLM_1531	COG0531	amino acid
DLM_1534	COG1129	ABC transporter
DLM_1535	COG1172	Belongs to the binding-protein-dependent transport system permease family
DLM_1536	COG1172	Belongs to the binding-protein-dependent transport system permease family
DLM_1541	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DLM_1543	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DLM_1545	COG0431	NADPH-dependent FMN reductase
DLM_1552	COG0410	ABC transporter
DLM_1554	COG3938	Belongs to the proline racemase family
DLM_1555	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DLM_1557	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_1560	COG0473	3-isopropylmalate dehydrogenase activity
DLM_1561	COG0583	DNA-binding transcription factor activity
DLM_1563	COG0583	DNA-binding transcription factor activity
DLM_1564	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
DLM_1566	COG2707	UPF0756 membrane protein
DLM_1589	COG3501	Rhs element vgr protein
DLM_1594	COG1876	peptidase activity
DLM_1607	COG1309	transcriptional regulator
DLM_1614	COG2963	transposase activity
DLM_1615	COG2801	Transposase and inactivated derivatives
DLM_1621	COG2963	transposase activity
DLM_1629	COG2831	hemolysin activation secretion protein
DLM_1633	COG2963	transposase activity
DLM_1635	COG0497	DNA recombination
DLM_1636	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DLM_1639	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DLM_1640	COG0123	including yeast histone deacetylase and acetoin utilization protein
DLM_1646	COG2197	response regulator
DLM_1647	COG1012	belongs to the aldehyde dehydrogenase family
DLM_1654	COG0583	DNA-binding transcription factor activity
DLM_1656	COG2119	membrane
DLM_1657	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DLM_1659	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_1662	COG2824	Alkylphosphonate utilization operon protein PhnA
DLM_1663	COG0534	Mate efflux family protein
DLM_1670	COG0415	Belongs to the DNA photolyase family
DLM_1671	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
DLM_1673	COG3040	lipid binding
DLM_1674	COG3046	protein related to deoxyribodipyrimidine photolyase
DLM_1675	COG0415	Belongs to the DNA photolyase family
DLM_1678	COG4221	oxidoreductase activity
DLM_1680	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DLM_1682	COG0493	'glutamate synthase
DLM_1683	COG1309	transcriptional regulator
DLM_1686	COG0745	RESPONSE REGULATOR receiver
DLM_1686	COG3706	GGDEF domain
DLM_1688	COG0009	L-threonylcarbamoyladenylate synthase
DLM_1689	COG3002	Belongs to the UPF0753 family
DLM_1690	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DLM_1691	COG0583	DNA-binding transcription factor activity
DLM_1697	COG1538	Outer membrane efflux protein
DLM_1699	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DLM_1701	COG0745	RESPONSE REGULATOR receiver
DLM_1702	COG5002	protein histidine kinase activity
DLM_1705	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DLM_1709	COG0679	Auxin Efflux Carrier
DLM_1711	COG1802	Transcriptional regulator
DLM_1712	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_1715	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DLM_1721	COG3052	prosthetic group binding
DLM_1726	COG2199	diguanylate cyclase activity
DLM_1726	COG2200	EAL domain
DLM_1731	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DLM_1732	COG1686	Belongs to the peptidase S11 family
DLM_1733	COG2921	Belongs to the UPF0250 family
DLM_1734	COG0321	lipoyl(octanoyl) transferase activity
DLM_1735	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DLM_1741	COG1278	Cold shock
DLM_1743	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DLM_1744	COG0420	3'-5' exonuclease activity
DLM_1745	COG0419	ATPase involved in DNA repair
DLM_1751	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DLM_1757	COG2217	Heavy metal translocating P-type atpase
DLM_1762	COG0747	negative chemotaxis
DLM_1764	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DLM_1765	COG1538	Outer membrane efflux protein
DLM_1766	COG1309	transcriptional regulator
DLM_1768	COG4974	Belongs to the 'phage' integrase family
DLM_1791	COG0667	Aldo Keto reductase
DLM_1794	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DLM_1795	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DLM_1797	COG0739	heme binding
DLM_1798	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DLM_1799	COG1674	ftsk spoiiie
DLM_1800	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DLM_1803	COG1312	Catalyzes the dehydration of D-mannonate
DLM_1804	COG2271	Major facilitator Superfamily
DLM_1805	COG0473	3-isopropylmalate dehydrogenase activity
DLM_1805	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DLM_1807	COG1024	Enoyl-CoA hydratase
DLM_1810	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DLM_1813	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DLM_1820	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DLM_1826	COG0436	Aminotransferase
DLM_1827	COG1522	sequence-specific DNA binding
DLM_1830	COG4149	molybdate abc transporter
DLM_1831	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DLM_1834	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DLM_1835	COG0513	Belongs to the DEAD box helicase family
DLM_1837	COG3437	response regulator, receiver
DLM_1838	COG0840	transmembrane signaling receptor activity
DLM_1840	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DLM_1846	COG2199	diguanylate cyclase activity
DLM_1846	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DLM_1847	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DLM_1851	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DLM_1852	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DLM_1853	COG0174	glutamine synthetase
DLM_1856	COG1538	Outer membrane efflux protein
DLM_1858	COG2814	Major facilitator Superfamily
DLM_1859	COG1538	Outer membrane efflux protein
DLM_1860	COG0577	efflux transmembrane transporter activity
DLM_1860	COG1136	(ABC) transporter
DLM_1861	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLM_1863	COG2197	response regulator
DLM_1864	COG0512	Glutamine amidotransferase of anthranilate synthase
DLM_1865	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DLM_1870	COG1335	isochorismatase
DLM_1873	COG1741	Belongs to the pirin family
DLM_1877	COG0047	phosphoribosylformylglycinamidine synthase activity
DLM_1877	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DLM_1882	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DLM_1882	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DLM_1885	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DLM_1898	COG3550	peptidyl-serine autophosphorylation
DLM_1900	COG3042	response to heat
DLM_1902	COG0840	transmembrane signaling receptor activity
DLM_1904	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_1905	COG0765	amino acid transport
DLM_1909	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_1910	COG0765	amino acid transport
DLM_1916	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DLM_1918	COG0583	DNA-binding transcription factor activity
DLM_1922	COG0243	molybdopterin cofactor binding
DLM_1924	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DLM_1925	COG2223	nitrite transmembrane transporter activity
DLM_1926	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DLM_1926	COG1116	anion transmembrane transporter activity
DLM_1927	COG3707	response regulator
DLM_1931	COG0583	DNA-binding transcription factor activity
DLM_1933	COG4191	Histidine kinase
DLM_1939	COG0583	DNA-binding transcription factor activity
DLM_1947	COG2198	Histidine kinase
DLM_1947	COG2205	protein histidine kinase activity
DLM_1947	COG0784	Response regulator, receiver
DLM_1948	COG2197	response regulator
DLM_1950	COG3842	ATPase activity
DLM_1952	COG1176	ABC-type spermidine putrescine transport system, permease component I
DLM_1953	COG1177	transmembrane transport
DLM_1955	COG3706	GGDEF domain
DLM_1958	COG1763	Mo-molybdopterin cofactor biosynthetic process
DLM_1962	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DLM_1963	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DLM_1964	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DLM_1965	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DLM_1966	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DLM_1970	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DLM_1971	COG0575	Belongs to the CDS family
DLM_1972	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DLM_1973	COG0233	cytoplasmic translational termination
DLM_1974	COG0528	UMP kinase activity
DLM_1975	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DLM_1976	COG0052	Belongs to the universal ribosomal protein uS2 family
DLM_1979	COG0477	Major facilitator Superfamily
DLM_1981	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DLM_1982	COG2816	NAD+ diphosphatase activity
DLM_1984	COG0166	Belongs to the GPI family
DLM_1985	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DLM_1986	COG0501	Belongs to the peptidase M48B family
DLM_1987	COG2154	pterin-4-alpha-carbinolamine dehydratase
DLM_1989	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_1990	COG1956	GAF domain-containing protein
DLM_1992	COG0745	RESPONSE REGULATOR receiver
DLM_1993	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DLM_1994	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DLM_1995	COG0443	Heat shock 70 kDa protein
DLM_1997	COG2321	neutral zinc metallopeptidase
DLM_1998	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DLM_2000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DLM_2001	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DLM_2003	COG0307	riboflavin synthase, alpha
DLM_2004	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DLM_2007	COG1063	alcohol dehydrogenase
DLM_2008	COG0842	Transport permease protein
DLM_2009	COG0842	Transport permease protein
DLM_2009	COG1129	ABC transporter
DLM_2010	COG1131	(ABC) transporter
DLM_2011	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLM_2013	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
DLM_2017	COG5001	Diguanylate cyclase
DLM_2017	COG5002	protein histidine kinase activity
DLM_2017	COG3447	MASE1 domain protein
DLM_2021	COG0583	DNA-binding transcription factor activity
DLM_2023	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DLM_2024	COG0745	RESPONSE REGULATOR receiver
DLM_2027	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DLM_2028	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DLM_2029	COG1045	serine acetyltransferase
DLM_2032	COG2011	ABC-type metal ion transport system permease component
DLM_2033	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DLM_2036	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DLM_2037	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DLM_2038	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DLM_2039	COG0431	NADPH-dependent FMN reductase
DLM_2042	COG1113	amino acid transport
DLM_2049	COG2159	amidohydrolase
DLM_2050	COG3384	dioxygenase
DLM_2052	COG2828	Protein conserved in bacteria
DLM_2053	COG0583	DNA-binding transcription factor activity
DLM_2054	COG0583	DNA-binding transcription factor activity
DLM_2060	COG1473	amidohydrolase
DLM_2061	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DLM_2062	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DLM_2071	COG0281	malic enzyme
DLM_2071	COG0280	phosphate acetyltransferase
DLM_2093	COG5005	Phage virion morphogenesis
DLM_2095	COG4383	Mu-like prophage protein gp29
DLM_2096	COG4373	Mu-like prophage FluMu protein gp28
DLM_2104	COG3023	N-Acetylmuramoyl-L-alanine amidase
DLM_2109	COG0776	regulation of translation
DLM_2115	COG2801	Transposase and inactivated derivatives
DLM_2125	COG0450	alkyl hydroperoxide reductase
DLM_2126	COG2175	clavaminate synthase activity
DLM_2129	COG0477	Major facilitator Superfamily
DLM_2133	COG2814	Major facilitator Superfamily
DLM_2138	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DLM_2141	COG3501	Rhs element vgr protein
DLM_2147	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DLM_2149	COG1082	Xylose isomerase domain protein TIM barrel
DLM_2153	COG0667	Aldo Keto reductase
DLM_2159	COG2159	amidohydrolase
DLM_2160	COG2828	Protein conserved in bacteria
DLM_2162	COG0840	transmembrane signaling receptor activity
DLM_2163	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DLM_2164	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DLM_2165	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DLM_2166	COG0840	transmembrane signaling receptor activity
DLM_2169	COG2822	iron ion transport
DLM_2171	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DLM_2172	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DLM_2173	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DLM_2174	COG2372	response to copper ion
DLM_2175	COG1276	copper resistance
DLM_2187	COG0114	fumarate hydratase activity
DLM_2188	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
DLM_2190	COG1278	Cold shock
DLM_2191	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DLM_2194	COG0583	DNA-binding transcription factor activity
DLM_2195	COG2814	Major facilitator Superfamily
DLM_2196	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DLM_2197	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DLM_2198	COG2249	NAD(P)H dehydrogenase (quinone) activity
DLM_2203	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DLM_2204	COG0798	PFAM Bile acid sodium symporter
DLM_2207	COG2072	flavoprotein involved in K transport
DLM_2210	COG2205	protein histidine kinase activity
DLM_2210	COG3437	response regulator, receiver
DLM_2210	COG4999	Histidine kinase
DLM_2210	COG3850	Histidine kinase
DLM_2211	COG1492	cobalamin metabolic process
DLM_2212	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DLM_2214	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DLM_2220	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DLM_2221	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DLM_2221	COG1648	precorrin-2 dehydrogenase activity
DLM_2222	COG2875	Belongs to the precorrin methyltransferase family
DLM_2227	COG1797	cobyrinic acid a,c-diamide synthase activity
DLM_2228	COG0778	Nitroreductase
DLM_2229	COG0583	DNA-binding transcription factor activity
DLM_2236	COG0439	Biotin carboxylase
DLM_2237	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
DLM_2238	COG1984	allophanate hydrolase subunit 2
DLM_2243	COG1289	transmembrane transporter activity
DLM_2247	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DLM_2248	COG2200	EAL domain
DLM_2249	COG3123	guanosine phosphorylase activity
DLM_2252	COG0412	Dienelactone hydrolase
DLM_2253	COG0643	Histidine kinase
DLM_2253	COG2198	Histidine kinase
DLM_2255	COG1278	Cold shock
DLM_2260	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DLM_2267	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DLM_2268	COG3706	GGDEF domain
DLM_2272	COG2205	protein histidine kinase activity
DLM_2273	COG0745	RESPONSE REGULATOR receiver
DLM_2275	COG0583	DNA-binding transcription factor activity
DLM_2277	COG0312	modulator of DNA gyrase
DLM_2278	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DLM_2280	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DLM_2283	COG0859	PFAM glycosyl transferase family 9
DLM_2284	COG1309	transcriptional regulator
DLM_2287	COG0492	ferredoxin-NADP+ reductase activity
DLM_2289	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DLM_2290	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DLM_2292	COG2096	Adenosyltransferase
DLM_2295	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DLM_2298	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DLM_2300	COG0840	transmembrane signaling receptor activity
DLM_2303	COG1739	Uncharacterized protein family UPF0029
DLM_2307	COG2917	probably involved in intracellular septation
DLM_2308	COG2350	Protein conserved in bacteria
DLM_2310	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DLM_2311	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DLM_2312	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DLM_2313	COG4589	Belongs to the CDS family
DLM_2315	COG2267	carboxylic ester hydrolase activity
DLM_2316	COG0671	phosphoesterase, PA-phosphatase related
DLM_2316	COG2453	phosphatase
DLM_2321	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
DLM_2322	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
DLM_2331	COG3210	domain, Protein
DLM_2335	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DLM_2336	COG1773	rubredoxin
DLM_2342	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DLM_2346	COG2204	response regulator
DLM_2349	COG2318	DinB family
DLM_2350	COG0840	transmembrane signaling receptor activity
DLM_2352	COG1215	transferase activity, transferring glycosyl groups
DLM_2353	COG1649	PFAM Uncharacterised BCR, COG1649
DLM_2353	COG0726	polysaccharide deacetylase
DLM_2355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_2355	COG4191	Histidine kinase
DLM_2356	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DLM_2357	COG1764	response to oxidative stress
DLM_2358	COG1917	Cupin 2, conserved barrel domain protein
DLM_2358	COG4977	sequence-specific DNA binding
DLM_2364	COG2866	Carboxypeptidase
DLM_2371	COG1970	mechanosensitive ion channel activity
DLM_2378	COG1012	belongs to the aldehyde dehydrogenase family
DLM_2380	COG2205	protein histidine kinase activity
DLM_2380	COG0784	Response regulator, receiver
DLM_2384	COG0840	transmembrane signaling receptor activity
DLM_2385	COG0477	Major facilitator Superfamily
DLM_2387	COG0583	DNA-binding transcription factor activity
DLM_2388	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DLM_2389	COG1518	maintenance of DNA repeat elements
DLM_2392	COG1857	crispr-associated protein
DLM_2399	COG0776	regulation of translation
DLM_2400	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DLM_2400	COG0072	phenylalanine-tRNA ligase activity
DLM_2401	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DLM_2402	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DLM_2403	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DLM_2405	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DLM_2408	COG0343	queuine tRNA-ribosyltransferase activity
DLM_2409	COG1862	Preprotein translocase
DLM_2410	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DLM_2411	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DLM_2412	COG0586	Pfam SNARE associated Golgi protein
DLM_2414	COG1435	thymidine kinase activity
DLM_2415	COG2925	Exonuclease
DLM_2416	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DLM_2417	COG0251	oxidation-reduction process
DLM_2419	COG1914	H( )-stimulated, divalent metal cation uptake system
DLM_2426	COG0482	sulfurtransferase activity
DLM_2429	COG0531	amino acid
DLM_2430	COG1166	arginine decarboxylase activity
DLM_2431	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_2432	COG3842	ATPase activity
DLM_2433	COG2200	EAL domain
DLM_2435	COG1024	Enoyl-CoA hydratase
DLM_2435	COG1250	3-hydroxyacyl-CoA dehydrogenase
DLM_2438	COG1256	bacterial-type flagellum assembly
DLM_2439	COG1705	Flagellar rod assembly protein muramidase FlgJ
DLM_2439	COG3951	Flagellar rod assembly protein muramidase FlgJ
DLM_2440	COG1706	bacterial-type flagellum-dependent cell motility
DLM_2441	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DLM_2442	COG4786	Flagellar basal body rod
DLM_2444	COG1749	Flagellar hook protein flgE
DLM_2446	COG1558	bacterial-type flagellum-dependent cell motility
DLM_2447	COG1815	bacterial-type flagellum-dependent cell motility
DLM_2449	COG1765	OsmC-like protein
DLM_2450	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DLM_2451	COG0488	(ABC) transporter
DLM_2453	COG0277	FAD linked oxidase domain protein
DLM_2454	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DLM_2455	COG0159	tryptophan synthase activity
DLM_2456	COG0133	tryptophan synthase activity
DLM_2458	COG0101	tRNA pseudouridine synthase activity
DLM_2463	COG0473	3-isopropylmalate dehydrogenase activity
DLM_2464	COG2226	methyltransferase
DLM_2465	COG0066	3-isopropylmalate dehydratase activity
DLM_2466	COG5510	response to toxic substance
DLM_2467	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DLM_2470	COG2814	Major facilitator Superfamily
DLM_2471	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DLM_2472	COG0179	Fumarylacetoacetate (FAA) hydrolase
DLM_2473	COG3243	poly(R)-hydroxyalkanoic acid synthase
DLM_2474	COG0183	Belongs to the thiolase family
DLM_2479	COG2267	carboxylic ester hydrolase activity
DLM_2480	COG1187	pseudouridine synthase activity
DLM_2481	COG0697	spore germination
DLM_2484	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DLM_2484	COG3008	intermembrane lipid transfer
DLM_2485	COG2995	paraquat-inducible protein a
DLM_2490	COG0583	DNA-binding transcription factor activity
DLM_2491	COG1454	alcohol dehydrogenase
DLM_2494	COG0833	amino acid
DLM_2496	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DLM_2500	COG1335	isochorismatase
DLM_2501	COG2070	2-Nitropropane dioxygenase
DLM_2503	COG1522	sequence-specific DNA binding
DLM_2505	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DLM_2507	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DLM_2508	COG0121	glutamine amidotransferase
DLM_2513	COG2003	Belongs to the UPF0758 family
DLM_2514	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DLM_2515	COG0756	dUTP diphosphatase activity
DLM_2516	COG3706	GGDEF domain
DLM_2518	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DLM_2520	COG0625	glutathione transferase activity
DLM_2521	COG0583	DNA-binding transcription factor activity
DLM_2524	COG0745	RESPONSE REGULATOR receiver
DLM_2524	COG3706	GGDEF domain
DLM_2525	COG0525	valine-tRNA ligase activity
DLM_2526	COG0840	transmembrane signaling receptor activity
DLM_2537	COG0300	oxidoreductase activity
DLM_2538	COG1722	exodeoxyribonuclease VII activity
DLM_2539	COG0142	geranyltranstransferase activity
DLM_2540	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DLM_2541	COG3174	membrane
DLM_2545	COG0628	permease
DLM_2546	COG0183	Belongs to the thiolase family
DLM_2547	COG0789	Transcriptional regulator
DLM_2548	COG1250	3-hydroxyacyl-CoA dehydrogenase
DLM_2550	COG1960	acyl-CoA dehydrogenase activity
DLM_2551	COG1024	Enoyl-CoA hydratase
DLM_2552	COG1024	Enoyl-CoA hydratase
DLM_2556	COG1058	Belongs to the CinA family
DLM_2556	COG1546	Belongs to the CinA family
DLM_2560	COG0559	Belongs to the binding-protein-dependent transport system permease family
DLM_2562	COG3724	N-succinylarginine dihydrolase activity
DLM_2563	COG1012	belongs to the aldehyde dehydrogenase family
DLM_2566	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DLM_2567	COG1185	polyribonucleotide nucleotidyltransferase activity
DLM_2568	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DLM_2569	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DLM_2570	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DLM_2571	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DLM_2572	COG0195	Participates in both transcription termination and antitermination
DLM_2572	COG2251	uridine kinase activity
DLM_2573	COG0779	Required for maturation of 30S ribosomal subunits
DLM_2574	COG0318	PFAM AMP-dependent synthetase and ligase
DLM_2576	COG1393	Belongs to the ArsC family
DLM_2577	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DLM_2582	COG2217	Heavy metal translocating P-type atpase
DLM_2583	COG2095	MarC family integral membrane protein
DLM_2585	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DLM_2586	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DLM_2588	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DLM_2589	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DLM_2590	COG2951	lytic endotransglycosylase activity
DLM_2591	COG1420	regulation of RNA biosynthetic process
DLM_2592	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DLM_2593	COG2137	regulation of response to DNA damage stimulus
DLM_2595	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DLM_2603	COG2308	Evidence 4 Homologs of previously reported genes of
DLM_2611	COG0788	formyltetrahydrofolate deformylase activity
DLM_2612	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DLM_2617	COG1802	Transcriptional regulator
DLM_2618	COG0583	DNA-binding transcription factor activity
DLM_2620	COG1741	Belongs to the pirin family
DLM_2624	COG4566	intracellular signal transduction
DLM_2625	COG3209	COG3209 Rhs family protein
DLM_2626	COG3209	COG3209 Rhs family protein
DLM_2628	COG3209	COG3209 Rhs family protein
DLM_2632	COG2963	transposase activity
DLM_2633	COG3209	COG3209 Rhs family protein
DLM_2635	COG3209	COG3209 Rhs family protein
DLM_2637	COG2801	Transposase and inactivated derivatives
DLM_2638	COG2963	transposase activity
DLM_2639	COG3209	COG3209 Rhs family protein
DLM_2640	COG3209	COG3209 Rhs family protein
DLM_2642	COG3209	COG3209 Rhs family protein
DLM_2643	COG3209	COG3209 Rhs family protein
DLM_2645	COG2801	Transposase and inactivated derivatives
DLM_2646	COG2963	transposase activity
DLM_2650	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DLM_2651	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_2652	COG1522	sequence-specific DNA binding
DLM_2654	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DLM_2655	COG3842	ATPase activity
DLM_2656	COG4208	sulfate ABC transporter
DLM_2675	COG4386	tail sheath protein
DLM_2680	COG4397	Mu-like prophage major head subunit gpT
DLM_2684	COG5005	Phage virion morphogenesis
DLM_2686	COG4383	Mu-like prophage protein gp29
DLM_2711	COG0745	RESPONSE REGULATOR receiver
DLM_2712	COG0784	Response regulator, receiver
DLM_2712	COG2205	protein histidine kinase activity
DLM_2712	COG5002	protein histidine kinase activity
DLM_2714	COG0745	RESPONSE REGULATOR receiver
DLM_2714	COG3706	GGDEF domain
DLM_2715	COG3186	Phenylalanine-4-hydroxylase
DLM_2717	COG2354	Protein conserved in bacteria
DLM_2721	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DLM_2722	COG3706	GGDEF domain
DLM_2724	COG2181	nitrate reductase activity
DLM_2725	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DLM_2726	COG1140	nitrate reductase beta subunit
DLM_2727	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DLM_2730	COG3539	Fimbrial protein
DLM_2733	COG2223	nitrite transmembrane transporter activity
DLM_2736	COG3850	Histidine kinase
DLM_2737	COG2197	response regulator
DLM_2738	COG3706	GGDEF domain
DLM_2739	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DLM_2740	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DLM_2742	COG1120	ATPase activity
DLM_2747	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DLM_2748	COG4774	siderophore transport
DLM_2751	COG0535	radical SAM domain protein
DLM_2754	COG3391	amine dehydrogenase activity
DLM_2761	COG0714	Associated with various cellular activities
DLM_2763	COG1845	cytochrome c oxidase, subunit III
DLM_2764	COG3256	nitric oxide reductase
DLM_2765	COG2010	Cytochrome c
DLM_2766	COG1648	precorrin-2 dehydrogenase activity
DLM_2766	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DLM_2780	COG0583	DNA-binding transcription factor activity
DLM_2783	COG2197	response regulator
DLM_2784	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_2785	COG4948	Mandelate Racemase Muconate Lactonizing
DLM_2786	COG3842	ATPase activity
DLM_2789	COG0395	ABC-type sugar transport system, permease component
DLM_2792	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DLM_2795	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DLM_2797	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DLM_2798	COG4689	acetoacetate decarboxylase
DLM_2799	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_2802	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DLM_2803	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DLM_2803	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DLM_2805	COG0284	orotidine-5'-phosphate decarboxylase activity
DLM_2806	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DLM_2808	COG0776	regulation of translation
DLM_2810	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DLM_2811	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DLM_2813	COG3038	cytochrome b561
DLM_2815	COG0583	DNA-binding transcription factor activity
DLM_2816	COG1609	Transcriptional regulator
DLM_2818	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DLM_2818	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DLM_2819	COG1105	Belongs to the carbohydrate kinase PfkB family
DLM_2820	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DLM_2820	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DLM_2821	COG2211	Major facilitator Superfamily
DLM_2824	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_2825	COG0023	Translation Initiation Factor
DLM_2827	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_2838	COG2885	chlorophyll binding
DLM_2838	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DLM_2840	COG3501	Rhs element vgr protein
DLM_2849	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_2850	COG0287	Prephenate dehydrogenase
DLM_2852	COG2199	diguanylate cyclase activity
DLM_2852	COG2200	EAL domain
DLM_2853	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DLM_2854	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DLM_2855	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DLM_2856	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DLM_2857	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_2858	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DLM_2859	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DLM_2860	COG0416	fatty acid biosynthetic process
DLM_2861	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DLM_2862	COG1399	metal-binding, possibly nucleic acid-binding protein
DLM_2863	COG0424	maF-like protein
DLM_2865	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DLM_2867	COG1704	LemA family
DLM_2873	COG0747	negative chemotaxis
DLM_2875	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DLM_2875	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DLM_2876	COG0509	glycine decarboxylation via glycine cleavage system
DLM_2877	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DLM_2880	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DLM_2881	COG2235	arginine
DLM_2882	COG0531	amino acid
DLM_2883	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DLM_2885	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DLM_2886	COG2201	protein-glutamate methylesterase activity
DLM_2887	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DLM_2888	COG0840	transmembrane signaling receptor activity
DLM_2890	COG2198	Histidine kinase
DLM_2890	COG0643	Histidine kinase
DLM_2891	COG0745	RESPONSE REGULATOR receiver
DLM_2892	COG0840	transmembrane signaling receptor activity
DLM_2894	COG3852	Histidine kinase
DLM_2895	COG0784	Response regulator, receiver
DLM_2895	COG0835	chemotaxis
DLM_2896	COG0784	Response regulator, receiver
DLM_2896	COG0835	chemotaxis
DLM_2897	COG0745	RESPONSE REGULATOR receiver
DLM_2898	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DLM_2899	COG0643	Histidine kinase
DLM_2899	COG2198	Histidine kinase
DLM_2900	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DLM_2901	COG1214	PFAM Peptidase M22, glycoprotease
DLM_2902	COG0456	acetyltransferase
DLM_2903	COG1573	uracil-dna glycosylase
DLM_2904	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DLM_2904	COG0519	Catalyzes the synthesis of GMP from XMP
DLM_2905	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DLM_2906	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DLM_2907	COG0504	CTP synthase activity
DLM_2908	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DLM_2909	COG0148	phosphopyruvate hydratase activity
DLM_2910	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DLM_2911	COG3706	GGDEF domain
DLM_2912	COG2914	Belongs to the UPF0125 (RnfH) family
DLM_2913	COG2867	negative regulation of translational initiation
DLM_2914	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DLM_2916	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DLM_2916	COG0519	Catalyzes the synthesis of GMP from XMP
DLM_2921	COG0590	tRNA wobble adenosine to inosine editing
DLM_2925	COG1671	Belongs to the UPF0178 family
DLM_2929	COG3706	GGDEF domain
DLM_2929	COG5001	Diguanylate cyclase
DLM_2929	COG2203	Gaf domain
DLM_2929	COG4251	negative regulation of phosphorylation
DLM_2930	COG0583	DNA-binding transcription factor activity
DLM_2932	COG1335	isochorismatase
DLM_2938	COG0004	ammonium transporteR
DLM_2943	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DLM_2946	COG5001	Diguanylate cyclase
DLM_2946	COG1716	ATPase activity
DLM_2951	COG0310	cobalt ion transport
DLM_2952	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DLM_2953	COG1122	ATPase activity
DLM_2958	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_2961	COG2885	chlorophyll binding
DLM_2962	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DLM_2963	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DLM_2966	COG4771	TonB-dependent receptor
DLM_2968	COG2205	protein histidine kinase activity
DLM_2971	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DLM_2974	COG1454	alcohol dehydrogenase
DLM_2975	COG4969	Belongs to the N-Me-Phe pilin family
DLM_2981	COG1309	transcriptional regulator
DLM_2982	COG0778	Nitroreductase
DLM_2983	COG1902	pentaerythritol trinitrate reductase activity
DLM_2985	COG1597	lipid kinase activity
DLM_2987	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DLM_2988	COG0720	synthase
DLM_2989	COG0602	queuosine metabolic process
DLM_2992	COG3220	belongs to the UPF0276 family
DLM_2995	COG0560	Phosphoserine phosphatase
DLM_2998	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DLM_3000	COG0400	carboxylic ester hydrolase activity
DLM_3005	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DLM_3008	COG0752	glycyl-tRNA synthetase alpha subunit
DLM_3012	COG1063	alcohol dehydrogenase
DLM_3014	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DLM_3015	COG4638	Rieske (2fe-2S)
DLM_3018	COG0473	3-isopropylmalate dehydrogenase activity
DLM_3019	COG0583	DNA-binding transcription factor activity
DLM_3024	COG0484	heat shock protein binding
DLM_3025	COG0443	Heat shock 70 kDa protein
DLM_3026	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DLM_3027	COG2224	Isocitrate lyase
DLM_3029	COG0531	amino acid
DLM_3030	COG0583	DNA-binding transcription factor activity
DLM_3032	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DLM_3037	COG0625	glutathione transferase activity
DLM_3038	COG1742	UPF0060 membrane protein
DLM_3039	COG0583	DNA-binding transcription factor activity
DLM_3044	COG2233	PERMEase
DLM_3045	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
DLM_3046	COG4266	Belongs to the allantoicase family
DLM_3048	COG3195	allantoin biosynthetic process
DLM_3048	COG3648	Uricase
DLM_3054	COG2084	Dehydrogenase
DLM_3055	COG3622	Belongs to the hyi family
DLM_3056	COG3960	tartronate-semialdehyde synthase activity
DLM_3058	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DLM_3059	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DLM_3060	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DLM_3061	COG0196	riboflavin kinase activity
DLM_3065	COG0175	sulfate reduction
DLM_3066	COG0583	DNA-binding transcription factor activity
DLM_3067	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_3068	COG0488	(ABC) transporter
DLM_3069	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DLM_3070	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DLM_3072	COG2850	peptidyl-arginine hydroxylation
DLM_3074	COG1047	Peptidyl-prolyl cis-trans
DLM_3076	COG2239	Acts as a magnesium transporter
DLM_3077	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DLM_3078	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DLM_3083	COG3852	Histidine kinase
DLM_3085	COG0583	DNA-binding transcription factor activity
DLM_3086	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DLM_3088	COG1346	cytolysis
DLM_3094	COG0494	nUDIX hydrolase
DLM_3095	COG0697	spore germination
DLM_3097	COG0560	Phosphoserine phosphatase
DLM_3098	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DLM_3100	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DLM_3101	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DLM_3103	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DLM_3103	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DLM_3105	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DLM_3106	COG5001	Diguanylate cyclase
DLM_3106	COG3300	MHYT domain
DLM_3107	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DLM_3109	COG2233	PERMEase
DLM_3110	COG0456	acetyltransferase
DLM_3111	COG0456	acetyltransferase
DLM_3112	COG0247	lactate metabolic process
DLM_3112	COG0277	FAD linked oxidase domain protein
DLM_3113	COG1335	isochorismatase
DLM_3123	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_3124	COG0359	binds to the 23S rRNA
DLM_3125	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DLM_3127	COG0360	Binds together with S18 to 16S ribosomal RNA
DLM_3129	COG1937	Protein conserved in bacteria
DLM_3131	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DLM_3133	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DLM_3135	COG0183	Belongs to the thiolase family
DLM_3136	COG1024	Enoyl-CoA hydratase
DLM_3138	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DLM_3139	COG2151	metal-sulfur cluster biosynthetic enzyme
DLM_3140	COG3396	Phenylacetate-CoA oxygenase
DLM_3141	COG3460	Phenylacetate-CoA oxygenase
DLM_3142	COG3396	Phenylacetate-CoA oxygenase
DLM_3144	COG1250	3-hydroxyacyl-CoA dehydrogenase
DLM_3145	COG1024	Enoyl-CoA hydratase
DLM_3146	COG1012	belongs to the aldehyde dehydrogenase family
DLM_3148	COG3162	membrane
DLM_3152	COG1012	belongs to the aldehyde dehydrogenase family
DLM_3152	COG1454	alcohol dehydrogenase
DLM_3153	COG0288	reversible hydration of carbon dioxide
DLM_3155	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_3157	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DLM_3160	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DLM_3163	COG3045	CreA protein
DLM_3165	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DLM_3165	COG0321	lipoyl(octanoyl) transferase activity
DLM_3166	COG0084	hydrolase, TatD family'
DLM_3168	COG0470	DNA polymerase III
DLM_3169	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DLM_3170	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DLM_3173	COG2186	Transcriptional regulator
DLM_3174	COG2807	transmembrane transport
DLM_3176	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DLM_3177	COG4181	ATPase activity
DLM_3179	COG0745	RESPONSE REGULATOR receiver
DLM_3179	COG3706	GGDEF domain
DLM_3180	COG3706	GGDEF domain
DLM_3181	COG0450	alkyl hydroperoxide reductase
DLM_3182	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DLM_3185	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DLM_3187	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DLM_3188	COG0268	Binds directly to 16S ribosomal RNA
DLM_3189	COG0728	peptidoglycan biosynthetic process
DLM_3191	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DLM_3191	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DLM_3194	COG0564	pseudouridine synthase activity
DLM_3195	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DLM_3196	COG0187	DNA topoisomerase II activity
DLM_3197	COG0494	nUDIX hydrolase
DLM_3198	COG0174	glutamine synthetase
DLM_3199	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_3200	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DLM_3208	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DLM_3211	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DLM_3212	COG4608	Belongs to the ABC transporter superfamily
DLM_3213	COG0444	Belongs to the ABC transporter superfamily
DLM_3214	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DLM_3215	COG0601	transmembrane transport
DLM_3216	COG0747	negative chemotaxis
DLM_3220	COG1104	cysteine desulfurase activity
DLM_3221	COG0822	iron-sulfur transferase activity
DLM_3223	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DLM_3224	COG0443	Heat shock 70 kDa protein
DLM_3225	COG0633	Ferredoxin
DLM_3227	COG0625	glutathione transferase activity
DLM_3228	COG0572	uridine kinase
DLM_3231	COG2610	gluconate transmembrane transporter activity
DLM_3232	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DLM_3233	COG0251	oxidation-reduction process
DLM_3234	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DLM_3239	COG3383	formate dehydrogenase (NAD+) activity
DLM_3249	COG4175	Glycine betaine
DLM_3252	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DLM_3255	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DLM_3256	COG2181	nitrate reductase activity
DLM_3256	COG0247	lactate metabolic process
DLM_3257	COG0446	pyridine nucleotide-disulphide oxidoreductase
DLM_3257	COG1902	pentaerythritol trinitrate reductase activity
DLM_3261	COG2113	Glycine betaine
DLM_3263	COG0477	Major facilitator Superfamily
DLM_3265	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DLM_3265	COG0446	pyridine nucleotide-disulphide oxidoreductase
DLM_3274	COG1012	belongs to the aldehyde dehydrogenase family
DLM_3278	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DLM_3278	COG1017	nitric oxide dioxygenase activity
DLM_3279	COG1959	2 iron, 2 sulfur cluster binding
DLM_3280	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DLM_3281	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DLM_3284	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
DLM_3289	COG4095	Psort location CytoplasmicMembrane, score
DLM_3290	COG0584	glycerophosphoryl diester phosphodiesterase
DLM_3291	COG1294	oxidase, subunit
DLM_3292	COG1271	oxidase subunit
DLM_3294	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DLM_3297	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
DLM_3300	COG0538	isocitrate dehydrogenase activity
DLM_3302	COG0477	Major facilitator Superfamily
DLM_3303	COG1278	Cold shock
DLM_3304	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DLM_3305	COG0542	response to heat
DLM_3306	COG4974	Belongs to the 'phage' integrase family
DLM_3307	COG0335	large ribosomal subunit rRNA binding
DLM_3308	COG0336	Belongs to the RNA methyltransferase TrmD family
DLM_3309	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DLM_3310	COG0228	four-way junction DNA binding
DLM_3311	COG0045	succinate-CoA ligase (ADP-forming) activity
DLM_3311	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DLM_3311	COG1042	CoA-binding domain protein
DLM_3312	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DLM_3313	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DLM_3314	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DLM_3315	COG1388	LysM domain
DLM_3315	COG4942	peptidase
DLM_3316	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DLM_3319	COG0714	Associated with various cellular activities
DLM_3320	COG0123	including yeast histone deacetylase and acetoin utilization protein
DLM_3321	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DLM_3325	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DLM_3326	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_3327	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DLM_3328	COG0316	Belongs to the HesB IscA family
DLM_3329	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DLM_3331	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DLM_3332	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DLM_3333	COG0813	purine-nucleoside phosphorylase activity
DLM_3334	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DLM_3335	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DLM_3336	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DLM_3338	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DLM_3339	COG1194	a g-specific adenine glycosylase
DLM_3341	COG2095	MarC family integral membrane protein
DLM_3344	COG1301	dicarboxylic acid transport
DLM_3345	COG0583	DNA-binding transcription factor activity
DLM_3349	COG0561	phosphatase activity
DLM_3352	COG0625	glutathione transferase activity
DLM_3354	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DLM_3357	COG1522	sequence-specific DNA binding
DLM_3358	COG1879	ABC-type sugar transport system periplasmic component
DLM_3359	COG5001	Diguanylate cyclase
DLM_3359	COG4251	negative regulation of phosphorylation
DLM_3359	COG3706	GGDEF domain
DLM_3359	COG2203	Gaf domain
DLM_3360	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DLM_3361	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DLM_3363	COG2969	positive regulation of protein catabolic process
DLM_3364	COG0625	glutathione transferase activity
DLM_3365	COG2857	Cytochrome c1
DLM_3366	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DLM_3367	COG0723	plastoquinol--plastocyanin reductase activity
DLM_3369	COG0459	protein refolding
DLM_3371	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DLM_3374	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DLM_3375	COG1086	Polysaccharide biosynthesis protein
DLM_3376	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DLM_3377	COG1861	Spore coat polysaccharide biosynthesis protein F CMP-KDO synthetase
DLM_3378	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DLM_3379	COG2089	acid synthase
DLM_3385	COG0493	'glutamate synthase
DLM_3387	COG0070	glutamate synthase
DLM_3387	COG0067	glutamate synthase
DLM_3387	COG0069	glutamate synthase activity
DLM_3389	COG1982	Orn Lys Arg decarboxylase major
DLM_3394	COG0626	cystathionine gamma-synthase activity
DLM_3395	COG1022	Amp-dependent synthetase and ligase
DLM_3401	COG1401	restriction endodeoxyribonuclease activity
DLM_3405	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
DLM_3407	COG0012	GTP binding
DLM_3408	COG0193	aminoacyl-tRNA hydrolase activity
DLM_3409	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DLM_3410	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DLM_3412	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DLM_3413	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DLM_3415	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DLM_3416	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DLM_3418	COG3245	cytochrome
DLM_3421	COG2193	ferroxidase activity
DLM_3422	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_3422	COG2205	protein histidine kinase activity
DLM_3425	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DLM_3428	COG1074	ATP-dependent DNA helicase activity
DLM_3429	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DLM_3434	COG0583	DNA-binding transcription factor activity
DLM_3435	COG2197	response regulator
DLM_3436	COG1012	belongs to the aldehyde dehydrogenase family
DLM_3438	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DLM_3444	COG0318	PFAM AMP-dependent synthetase and ligase
DLM_3449	COG0642	Histidine kinase
DLM_3450	COG0745	RESPONSE REGULATOR receiver
DLM_3454	COG0438	transferase activity, transferring glycosyl groups
DLM_3455	COG0473	3-isopropylmalate dehydrogenase activity
DLM_3459	COG2226	methyltransferase
DLM_3460	COG0708	Exodeoxyribonuclease III
DLM_3461	COG2194	sulfuric ester hydrolase activity
DLM_3463	COG0339	signal peptide processing
DLM_3464	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DLM_3467	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DLM_3469	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
DLM_3474	COG3501	Rhs element vgr protein
DLM_3477	COG0840	transmembrane signaling receptor activity
DLM_3479	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DLM_3483	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DLM_3485	COG1196	nuclear chromosome segregation
DLM_3489	COG0477	Major facilitator Superfamily
DLM_3490	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DLM_3491	COG0583	DNA-binding transcription factor activity
DLM_3496	COG4598	ABC transporter
DLM_3497	COG4160	amino acid transport
DLM_3498	COG4215	(ABC) transporter
DLM_3500	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DLM_3501	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DLM_3502	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DLM_3503	COG0142	geranyltranstransferase activity
DLM_3505	COG0582	viral genome integration into host DNA
DLM_3512	COG3596	GTP binding
DLM_3515	COG3501	Rhs element vgr protein
DLM_3516	COG2963	transposase activity
DLM_3520	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DLM_3520	COG2755	lipolytic protein G-D-S-L family
DLM_3522	COG1283	sodium-dependent phosphate transmembrane transporter activity
DLM_3523	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DLM_3524	COG1538	Outer membrane efflux protein
DLM_3526	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DLM_3527	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLM_3534	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DLM_3535	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DLM_3537	COG1132	(ABC) transporter
DLM_3541	COG0859	PFAM glycosyl transferase family 9
DLM_3543	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DLM_3544	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DLM_3546	COG1648	precorrin-2 dehydrogenase activity
DLM_3546	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DLM_3549	COG1295	ribonuclease BN
DLM_3549	COG1959	2 iron, 2 sulfur cluster binding
DLM_3552	COG2207	Transcriptional regulator
DLM_3553	COG2223	nitrite transmembrane transporter activity
DLM_3555	COG2814	Major facilitator Superfamily
DLM_3556	COG2813	Specifically methylates the guanine in position
DLM_3556	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DLM_3557	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DLM_3559	COG1242	4 iron, 4 sulfur cluster binding
DLM_3560	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DLM_3563	COG1250	3-hydroxyacyl-CoA dehydrogenase
DLM_3564	COG1024	Enoyl-CoA hydratase
DLM_3565	COG0477	Major facilitator Superfamily
DLM_3566	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DLM_3567	COG1960	acyl-CoA dehydrogenase activity
DLM_3568	COG0583	DNA-binding transcription factor activity
DLM_3576	COG1393	Belongs to the ArsC family
DLM_3577	COG1846	Transcriptional regulator
DLM_3579	COG1566	PFAM secretion protein HlyD family protein
DLM_3580	COG2814	Major facilitator Superfamily
DLM_3581	COG0583	DNA-binding transcription factor activity
DLM_3582	COG0583	DNA-binding transcription factor activity
DLM_3585	COG1129	ABC transporter
DLM_3588	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_3589	COG0800	Aldolase
DLM_3590	COG4948	Mandelate Racemase Muconate Lactonizing
DLM_3591	COG2017	converts alpha-aldose to the beta-anomer
DLM_3592	COG1063	alcohol dehydrogenase
DLM_3593	COG1172	Belongs to the binding-protein-dependent transport system permease family
DLM_3594	COG1129	ABC transporter
DLM_3595	COG1879	ABC-type sugar transport system periplasmic component
DLM_3604	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DLM_3604	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DLM_3605	COG1611	Belongs to the LOG family
DLM_3607	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DLM_3608	COG0583	DNA-binding transcription factor activity
DLM_3609	COG2855	membrane
DLM_3610	COG2879	small protein
DLM_3611	COG1966	Carbon starvation protein
DLM_3612	COG0745	RESPONSE REGULATOR receiver
DLM_3613	COG2205	protein histidine kinase activity
DLM_3616	COG0408	coproporphyrinogen oxidase activity
DLM_3617	COG3706	GGDEF domain
DLM_3618	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DLM_3619	COG0583	DNA-binding transcription factor activity
DLM_3623	COG0840	transmembrane signaling receptor activity
DLM_3627	COG4566	intracellular signal transduction
DLM_3629	COG0477	Major facilitator Superfamily
DLM_3631	COG0477	Major facilitator Superfamily
DLM_3632	COG0667	Aldo Keto reductase
DLM_3633	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
DLM_3642	COG3501	Rhs element vgr protein
DLM_3647	COG3501	Rhs element vgr protein
DLM_3651	COG1595	DNA-templated transcription, initiation
DLM_3653	COG4771	TonB-dependent receptor
DLM_3654	COG0612	Peptidase, M16
DLM_3655	COG4178	(ABC) transporter
DLM_3656	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DLM_3657	COG1349	DNA-binding transcription factor activity
DLM_3658	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DLM_3659	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DLM_3660	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DLM_3661	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DLM_3662	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DLM_3663	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DLM_3664	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DLM_3666	COG0356	it plays a direct role in the translocation of protons across the membrane
DLM_3669	COG1192	Involved in chromosome partitioning
DLM_3670	COG0357	Ribosomal RNA small subunit methyltransferase G
DLM_3671	COG0445	tRNA wobble uridine modification
DLM_3673	COG1720	tRNA m6t6A37 methyltransferase activity
DLM_3675	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DLM_3676	COG2823	Periplasmic or secreted lipoprotein
DLM_3677	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DLM_3678	COG0792	nuclease activity
DLM_3685	COG0515	serine threonine protein kinase
DLM_3686	COG0515	serine threonine protein kinase
DLM_3686	COG2815	serine threonine protein kinase
DLM_3690	COG0084	hydrolase, TatD family'
DLM_3692	COG1538	Outer membrane efflux protein
DLM_3697	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLM_3701	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DLM_3702	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DLM_3704	COG0140	phosphoribosyl-ATP diphosphatase activity
DLM_3705	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DLM_3706	COG0107	imidazoleglycerol-phosphate synthase activity
DLM_3707	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DLM_3708	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DLM_3709	COG0131	Imidazoleglycerol-phosphate dehydratase
DLM_3710	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DLM_3712	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DLM_3713	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DLM_3714	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DLM_3715	COG1999	signal sequence binding
DLM_3716	COG0109	protoheme IX farnesyltransferase activity
DLM_3717	COG1612	heme a metabolic process
DLM_3724	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DLM_3727	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DLM_3729	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DLM_3730	COG1183	phosphatidylcholine synthase activity
DLM_3731	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DLM_3732	COG0440	acetolactate synthase activity
DLM_3733	COG0028	Belongs to the TPP enzyme family
DLM_3738	COG1846	Transcriptional regulator
DLM_3739	COG1914	H( )-stimulated, divalent metal cation uptake system
DLM_3740	COG0741	lytic transglycosylase activity
DLM_3741	COG0442	prolyl-tRNA aminoacylation
DLM_3742	COG3158	transport of potassium into the cell
DLM_3744	COG3945	hemerythrin HHE cation binding domain
DLM_3745	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DLM_3748	COG0745	RESPONSE REGULATOR receiver
DLM_3749	COG1522	sequence-specific DNA binding
DLM_3750	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DLM_3751	COG2190	(PTS) system
DLM_3751	COG1263	PTS System
DLM_3751	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DLM_3752	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DLM_3753	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DLM_3754	COG2188	Transcriptional regulator
DLM_3755	COG0697	spore germination
DLM_3757	COG0009	L-threonylcarbamoyladenylate synthase
DLM_3762	COG0138	bifunctional purine biosynthesis protein purh
DLM_3764	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DLM_3767	COG1957	nucleoside hydrolase
DLM_3768	COG1473	amidohydrolase
DLM_3771	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DLM_3772	COG0508	dehydrogenase complex catalyzes the overall conversion of
DLM_3774	COG4783	chaperone-mediated protein folding
DLM_3778	COG0640	Transcriptional regulator
DLM_3782	COG0288	reversible hydration of carbon dioxide
DLM_3783	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DLM_3784	COG0799	negative regulation of ribosome biogenesis
DLM_3785	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DLM_3790	COG0450	alkyl hydroperoxide reductase
DLM_3792	COG0739	heme binding
DLM_3792	COG0741	lytic transglycosylase activity
DLM_3792	COG1196	nuclear chromosome segregation
DLM_3794	COG1466	dna polymerase III delta subunit
DLM_3795	COG2980	Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane
DLM_3796	COG0495	leucyl-tRNA aminoacylation
DLM_3801	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DLM_3805	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DLM_3807	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DLM_3813	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DLM_3815	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DLM_3816	COG4968	Prepilin-type N-terminal cleavage methylation domain
DLM_3828	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DLM_3829	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DLM_3833	COG4774	siderophore transport
DLM_3834	COG3128	pkhd-type hydroxylase
DLM_3835	COG0840	transmembrane signaling receptor activity
DLM_3841	COG0745	RESPONSE REGULATOR receiver
DLM_3841	COG3706	GGDEF domain
DLM_3842	COG5001	Diguanylate cyclase
DLM_3842	COG5002	protein histidine kinase activity
DLM_3842	COG3447	MASE1 domain protein
DLM_3845	COG0513	Belongs to the DEAD box helicase family
DLM_3847	COG4681	YaeQ
DLM_3849	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DLM_3851	COG1522	sequence-specific DNA binding
DLM_3853	COG1451	nucleotide metabolic process
DLM_3857	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DLM_3858	COG1132	(ABC) transporter
DLM_3859	COG2841	Protein conserved in bacteria
DLM_3860	COG3706	GGDEF domain
DLM_3863	COG3150	esterase
DLM_3864	COG0784	Response regulator, receiver
DLM_3864	COG5002	protein histidine kinase activity
DLM_3871	COG0745	RESPONSE REGULATOR receiver
DLM_3875	COG0069	glutamate synthase activity
DLM_3876	COG2963	transposase activity
DLM_3877	COG2801	Transposase and inactivated derivatives
DLM_3879	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DLM_3880	COG1177	transmembrane transport
DLM_3881	COG1176	ABC-type spermidine putrescine transport system, permease component I
DLM_3882	COG3842	ATPase activity
DLM_3888	COG0697	spore germination
DLM_3889	COG1522	sequence-specific DNA binding
DLM_3891	COG0006	proline dipeptidase activity
DLM_3895	COG3135	benzoate transporter
DLM_3896	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DLM_3897	COG0579	oxidoreductase
DLM_3906	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DLM_3908	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DLM_3923	COG1573	uracil-dna glycosylase
DLM_3925	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DLM_3926	COG2986	histidine ammonia-lyase
DLM_3927	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DLM_3928	COG0010	Belongs to the arginase family
DLM_3929	COG1228	amidohydrolase
DLM_3930	COG1968	undecaprenyl-diphosphatase activity
DLM_3931	COG2188	Transcriptional regulator
DLM_3932	COG0676	glucose-6-phosphate 1-epimerase activity
DLM_3934	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DLM_3936	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DLM_3939	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DLM_3948	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
DLM_3949	COG0540	Belongs to the ATCase OTCase family
DLM_3951	COG1280	lysine exporter protein (LysE YggA)
DLM_3955	COG0668	transmembrane transport
DLM_3956	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DLM_3958	COG0625	glutathione transferase activity
DLM_3959	COG4628	conserved protein (DUF2132)
DLM_3965	COG0826	peptidase U32
DLM_3967	COG3214	Protein conserved in bacteria
DLM_3970	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DLM_3971	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DLM_3973	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DLM_3974	COG1253	flavin adenine dinucleotide binding
DLM_3975	COG4651	solute:proton antiporter activity
DLM_3975	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DLM_3981	COG0859	PFAM glycosyl transferase family 9
DLM_3982	COG1519	Transferase
DLM_3984	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DLM_3985	COG1131	(ABC) transporter
DLM_3986	COG0842	Transport permease protein
DLM_3987	COG0842	Transport permease protein
DLM_3990	COG0583	DNA-binding transcription factor activity
DLM_3991	COG0352	thiamine-phosphate diphosphorylase activity
DLM_3992	COG0351	phosphomethylpyrimidine kinase
DLM_3993	COG1773	rubredoxin
DLM_3994	COG4783	chaperone-mediated protein folding
DLM_3998	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DLM_4002	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DLM_4006	COG2378	regulation of single-species biofilm formation
DLM_4010	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DLM_4013	COG1238	metal cluster binding
DLM_4014	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DLM_4015	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_4016	COG0765	amino acid transport
DLM_4017	COG0765	amino acid transport
DLM_4018	COG1126	abc transporter atp-binding protein
DLM_4019	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DLM_4025	COG0762	integral membrane protein
DLM_4026	COG4654	Cytochrome c, class I
DLM_4027	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DLM_4028	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DLM_4030	COG0583	DNA-binding transcription factor activity
DLM_4031	COG0314	molybdopterin synthase activity
DLM_4032	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DLM_4035	COG1280	lysine exporter protein (LysE YggA)
DLM_4036	COG0126	phosphoglycerate kinase activity
DLM_4037	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DLM_4038	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DLM_4040	COG2153	protein acetylation
DLM_4049	COG4753	response regulator
DLM_4049	COG2207	Transcriptional regulator
DLM_4050	COG2201	protein-glutamate methylesterase activity
DLM_4051	COG2205	protein histidine kinase activity
DLM_4051	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DLM_4052	COG0583	DNA-binding transcription factor activity
DLM_4053	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DLM_4054	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DLM_4055	COG0259	pyridoxamine-phosphate oxidase activity
DLM_4056	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DLM_4062	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DLM_4063	COG0583	DNA-binding transcription factor activity
DLM_4069	COG1132	(ABC) transporter
DLM_4071	COG0583	DNA-binding transcription factor activity
DLM_4073	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DLM_4075	COG5001	Diguanylate cyclase
DLM_4075	COG4251	negative regulation of phosphorylation
DLM_4075	COG3706	GGDEF domain
DLM_4075	COG2203	Gaf domain
DLM_4077	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DLM_4078	COG0235	Class ii aldolase
DLM_4083	COG1858	cytochrome C peroxidase
DLM_4087	COG2066	Belongs to the glutaminase family
DLM_4094	COG0864	Transcriptional regulator
DLM_4098	COG2963	transposase activity
DLM_4099	COG2801	Transposase and inactivated derivatives
DLM_4100	COG3012	SEC-C Motif Domain Protein
DLM_4103	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DLM_4104	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DLM_4105	COG0594	ribonuclease P activity
DLM_4106	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DLM_4107	COG0706	membrane insertase activity
DLM_4108	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DLM_4109	COG0582	viral genome integration into host DNA
DLM_4116	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DLM_4117	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DLM_4118	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DLM_4121	COG2959	enzyme of heme biosynthesis
DLM_4123	COG0181	hydroxymethylbilane synthase activity
DLM_4124	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DLM_4127	COG3275	phosphorelay sensor kinase activity
DLM_4130	COG0165	Argininosuccinate lyase
DLM_4131	COG2200	EAL domain
DLM_4134	COG3706	GGDEF domain
DLM_4134	COG0745	RESPONSE REGULATOR receiver
DLM_4135	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
DLM_4137	COG4989	oxidoreductase activity
DLM_4138	COG3842	ATPase activity
DLM_4139	COG0395	ABC-type sugar transport system, permease component
DLM_4142	COG2205	protein histidine kinase activity
DLM_4144	COG0800	Aldolase
DLM_4145	COG0129	dihydroxy-acid dehydratase activity
DLM_4146	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DLM_4148	COG0837	glucose binding
DLM_4150	COG0166	Belongs to the GPI family
DLM_4153	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DLM_4155	COG2827	Endonuclease containing a URI domain
DLM_4156	COG1253	flavin adenine dinucleotide binding
DLM_4157	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DLM_4158	COG1333	cytochrome c biogenesis protein
DLM_4160	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DLM_4162	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DLM_4163	COG1040	competence protein
DLM_4164	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DLM_4165	COG0156	8-amino-7-oxononanoate synthase activity
DLM_4166	COG3300	MHYT domain
DLM_4166	COG5001	Diguanylate cyclase
DLM_4167	COG2267	carboxylic ester hydrolase activity
DLM_4168	COG2226	methyltransferase
DLM_4169	COG1752	Esterase of the alpha-beta hydrolase superfamily
DLM_4170	COG0625	glutathione transferase activity
DLM_4172	COG2847	Copper chaperone PCu(A)C
DLM_4175	COG3791	Glutathione-dependent formaldehyde-activating
DLM_4178	COG0772	Belongs to the SEDS family
DLM_4179	COG0768	penicillin binding
DLM_4180	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DLM_4181	COG1792	Involved in formation and maintenance of cell shape
DLM_4182	COG1077	Cell shape determining protein MreB Mrl
DLM_4183	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DLM_4184	COG0154	amidase activity
DLM_4186	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DLM_4187	COG2001	Belongs to the MraZ family
DLM_4188	COG0275	rRNA processing
DLM_4189	COG3116	cell division
DLM_4191	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DLM_4192	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DLM_4193	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DLM_4194	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DLM_4195	COG0772	Belongs to the SEDS family
DLM_4196	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DLM_4197	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DLM_4198	COG1181	Belongs to the D-alanine--D-alanine ligase family
DLM_4199	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DLM_4203	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DLM_4205	COG0315	cyclic pyranopterin monophosphate synthase activity
DLM_4212	COG0418	dihydroorotase activity
DLM_4213	COG4166	transmembrane transport
DLM_4214	COG0601	transmembrane transport
DLM_4215	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DLM_4217	COG0501	Belongs to the peptidase M48B family
DLM_4218	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DLM_4222	COG1505	serine-type exopeptidase activity
DLM_4226	COG3132	Protein of unknown function, DUF480
DLM_4229	COG0589	response to stress
DLM_4231	COG0405	Gamma-glutamyltransferase
DLM_4232	COG0174	glutamine synthetase
DLM_4234	COG0840	transmembrane signaling receptor activity
DLM_4238	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DLM_4242	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DLM_4243	COG0840	transmembrane signaling receptor activity
DLM_4248	COG4208	sulfate ABC transporter
DLM_4249	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DLM_4252	COG1116	anion transmembrane transporter activity
DLM_4255	COG0653	protein targeting
DLM_4256	COG0424	maF-like protein
DLM_4257	COG1530	ribonuclease E activity
DLM_4258	COG1045	serine acetyltransferase
DLM_4262	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DLM_4266	COG0210	DNA helicase
DLM_4275	COG0823	Involved in the tonB-independent uptake of proteins
DLM_4277	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
DLM_4280	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DLM_4281	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DLM_4282	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DLM_4283	COG2267	carboxylic ester hydrolase activity
DLM_4286	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DLM_4293	COG3433	isochorismatase activity
DLM_4293	COG2226	methyltransferase
DLM_4293	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
DLM_4296	COG1902	pentaerythritol trinitrate reductase activity
DLM_4296	COG0446	pyridine nucleotide-disulphide oxidoreductase
DLM_4297	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DLM_4301	COG0189	ligase activity
DLM_4307	COG2922	Belongs to the Smg family
DLM_4308	COG0758	DNA mediated transformation
DLM_4310	COG0242	peptide deformylase activity
DLM_4311	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DLM_4312	COG0501	Belongs to the peptidase M48B family
DLM_4316	COG5000	phosphorelay sensor kinase activity
DLM_4317	COG2204	response regulator
DLM_4319	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DLM_4320	COG0824	Thioesterase
DLM_4323	COG0783	Belongs to the Dps family
DLM_4324	COG1872	DUF167
DLM_4326	COG1324	tolerance protein
DLM_4335	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DLM_4336	COG0708	Exodeoxyribonuclease III
DLM_4341	COG1253	flavin adenine dinucleotide binding
DLM_4346	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DLM_4347	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DLM_4348	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DLM_4351	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DLM_4353	COG0632	four-way junction helicase activity
DLM_4354	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DLM_4355	COG2255	four-way junction helicase activity
DLM_4356	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DLM_4356	COG0519	Catalyzes the synthesis of GMP from XMP
DLM_4359	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DLM_4363	COG3307	-O-antigen
DLM_4364	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DLM_4366	COG2884	Cell division ATP-binding protein ftsE
DLM_4368	COG0612	Peptidase, M16
DLM_4369	COG0612	Peptidase, M16
DLM_4370	COG0742	ribosomal rna small subunit methyltransferase
DLM_4371	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DLM_4375	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DLM_4379	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DLM_4380	COG0081	regulation of translation
DLM_4382	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DLM_4383	COG0222	ribosome binding
DLM_4384	COG0085	RNA polymerase activity
DLM_4385	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DLM_4386	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DLM_4387	COG0049	tRNA binding
DLM_4388	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DLM_4389	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DLM_4390	COG0051	transcription antitermination factor activity, RNA binding
DLM_4391	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DLM_4392	COG0088	Forms part of the polypeptide exit tunnel
DLM_4393	COG0089	rRNA binding
DLM_4394	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DLM_4395	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DLM_4396	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DLM_4397	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DLM_4398	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DLM_4399	COG0255	Belongs to the universal ribosomal protein uL29 family
DLM_4400	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DLM_4402	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DLM_4403	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DLM_4404	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DLM_4405	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DLM_4406	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DLM_4407	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DLM_4408	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DLM_4409	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DLM_4410	COG1841	ribosomal large subunit assembly
DLM_4411	COG0200	Binds to the 23S rRNA
DLM_4412	COG0201	protein transport
DLM_4413	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DLM_4414	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DLM_4415	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DLM_4417	COG0202	RNA polymerase activity
DLM_4418	COG0203	ribosomal protein L17
DLM_4419	COG3217	Mosc domain protein beta barrel domain protein
DLM_4419	COG0633	Ferredoxin
DLM_4420	COG0840	transmembrane signaling receptor activity
DLM_4421	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DLM_4422	COG4535	Mg2 and Co2 transporter CorC
DLM_4423	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DLM_4424	COG1702	phosphate starvation-inducible protein PhoH
DLM_4427	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DLM_4429	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DLM_4430	COG1869	D-ribose catabolic process
DLM_4431	COG1129	ABC transporter
DLM_4432	COG1172	Belongs to the binding-protein-dependent transport system permease family
DLM_4433	COG1879	ABC-type sugar transport system periplasmic component
DLM_4437	COG1187	pseudouridine synthase activity
DLM_4438	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DLM_4442	COG1028	Short-chain dehydrogenase reductase Sdr
DLM_4443	COG0037	tRNA processing
DLM_4444	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DLM_4453	COG0297	glycogen (starch) synthase activity
DLM_4458	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DLM_4459	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DLM_4461	COG3706	GGDEF domain
DLM_4462	COG0583	DNA-binding transcription factor activity
DLM_4463	COG0406	alpha-ribazole phosphatase activity
DLM_4464	COG1027	Aspartate ammonia-lyase
DLM_4468	COG3171	Protein conserved in bacteria
DLM_4469	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DLM_4470	COG3047	cAMP biosynthetic process
DLM_4478	COG1131	(ABC) transporter
DLM_4479	COG0842	Transport permease protein
DLM_4481	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DLM_4482	COG0840	transmembrane signaling receptor activity
DLM_4484	COG2853	Lipoprotein
DLM_4487	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DLM_4488	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DLM_4489	COG1127	ABC transporter
DLM_4490	COG2171	N-acyltransferase activity
DLM_4494	COG2900	Belongs to the SlyX family
DLM_4497	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DLM_4499	COG0745	RESPONSE REGULATOR receiver
DLM_4499	COG3706	GGDEF domain
DLM_4500	COG2205	protein histidine kinase activity
DLM_4501	COG1192	Involved in chromosome partitioning
DLM_4503	COG0514	ATP-dependent DNA helicase (RecQ)
DLM_4504	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DLM_4517	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DLM_4519	COG1538	Outer membrane efflux protein
DLM_4520	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DLM_4523	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DLM_4525	COG1414	Transcriptional regulator
DLM_4527	COG1804	L-carnitine dehydratase bile acid-inducible protein F
DLM_4532	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DLM_4536	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DLM_4538	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DLM_4540	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DLM_4541	COG1846	Transcriptional regulator
DLM_4542	COG3038	cytochrome b561
DLM_4543	COG2353	YceI-like domain
DLM_4545	COG2223	nitrite transmembrane transporter activity
DLM_4547	COG1678	Uncharacterized ACR, COG1678
DLM_4548	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DLM_4553	COG1215	transferase activity, transferring glycosyl groups
DLM_4554	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DLM_4556	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
DLM_4558	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate