locus-tag	class	description
DKK66_00010	COG0037	tRNA processing
DKK66_00015	COG0825	malonyl-CoA metabolic process
DKK66_00040	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
DKK66_00050	COG0312	modulator of DNA gyrase
DKK66_00055	COG3028	Belongs to the UPF0307 family
DKK66_00060	COG0521	Mo-molybdopterin cofactor biosynthetic process
DKK66_00065	COG0429	hydrolase of the alpha beta-hydrolase fold
DKK66_00070	COG0134	indole-3-glycerol-phosphate synthase activity
DKK66_00075	COG1752	Esterase of the alpha-beta hydrolase superfamily
DKK66_00085	COG0183	Belongs to the thiolase family
DKK66_00090	COG1250	3-hydroxyacyl-CoA dehydrogenase
DKK66_00090	COG1024	Enoyl-CoA hydratase
DKK66_00105	COG1960	acyl-CoA dehydrogenase activity
DKK66_00125	COG1286	toxin biosynthetic process
DKK66_00130	COG3147	Non-essential cell division protein that could be required for efficient cell constriction
DKK66_00135	COG0285	dihydrofolate synthase activity
DKK66_00155	COG0791	NLP P60 protein
DKK66_00190	COG0542	response to heat
DKK66_00205	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
DKK66_00210	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
DKK66_00210	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DKK66_00220	COG0730	response to heat
DKK66_00235	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
DKK66_00240	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
DKK66_00245	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
DKK66_00250	COG2205	protein histidine kinase activity
DKK66_00255	COG0745	RESPONSE REGULATOR receiver
DKK66_00265	COG1181	Belongs to the D-alanine--D-alanine ligase family
DKK66_00280	COG2356	endonuclease I
DKK66_00285	COG1609	Transcriptional regulator
DKK66_00295	COG2271	Major facilitator Superfamily
DKK66_00305	COG0183	Belongs to the thiolase family
DKK66_00320	COG1349	DNA-binding transcription factor activity
DKK66_00325	COG0583	DNA-binding transcription factor activity
DKK66_00345	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
DKK66_00350	COG0830	nickel cation binding
DKK66_00360	COG0804	urea catabolic process
DKK66_00365	COG0832	Belongs to the urease beta subunit family
DKK66_00370	COG0831	urea catabolic process
DKK66_00385	COG0411	ABC transporter
DKK66_00395	COG0559	Belongs to the binding-protein-dependent transport system permease family
DKK66_00415	COG0789	Transcriptional regulator
DKK66_00420	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DKK66_00430	COG5002	protein histidine kinase activity
DKK66_00430	COG2198	Histidine kinase
DKK66_00430	COG0784	Response regulator, receiver
DKK66_00445	COG2814	Major facilitator Superfamily
DKK66_00450	COG2134	cdp-diacylglycerol pyrophosphatase
DKK66_00475	COG2223	nitrite transmembrane transporter activity
DKK66_00480	COG1012	belongs to the aldehyde dehydrogenase family
DKK66_00485	COG0038	chloride channel
DKK66_00495	COG0501	Belongs to the peptidase M48B family
DKK66_00500	COG0583	DNA-binding transcription factor activity
DKK66_00515	COG0686	Belongs to the AlaDH PNT family
DKK66_00530	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DKK66_00535	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DKK66_00540	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DKK66_00545	COG0006	proline dipeptidase activity
DKK66_00550	COG0217	transcriptional regulatory protein
DKK66_00555	COG1684	flagellar biosynthetic protein fliR
DKK66_00560	COG1987	bacterial-type flagellum assembly
DKK66_00580	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DKK66_00610	COG3842	ATPase activity
DKK66_00620	COG1157	protein secretion by the type III secretion system
DKK66_00630	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
DKK66_00635	COG1766	The M ring may be actively involved in energy transduction
DKK66_00640	COG1677	Flagellar hook-basal body complex protein FliE
DKK66_00645	COG2204	response regulator
DKK66_00650	COG2201	protein-glutamate methylesterase activity
DKK66_00655	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DKK66_00660	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
DKK66_00675	COG0840	transmembrane signaling receptor activity
DKK66_00690	COG0583	DNA-binding transcription factor activity
DKK66_00700	COG0556	nucleotide-excision repair
DKK66_00745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DKK66_00755	COG0531	amino acid
DKK66_00760	COG4303	Ethanolamine ammonia lyase large subunit
DKK66_00765	COG4302	ethanolamine ammonia-lyase activity
DKK66_00780	COG0784	Response regulator, receiver
DKK66_00780	COG0835	chemotaxis
DKK66_00785	COG0784	Response regulator, receiver
DKK66_00785	COG0835	chemotaxis
DKK66_00790	COG0745	RESPONSE REGULATOR receiver
DKK66_00795	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DKK66_00805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DKK66_00815	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DKK66_00820	COG3938	Belongs to the proline racemase family
DKK66_00860	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DKK66_00900	COG1840	ABC-type Fe3 transport system, periplasmic component
DKK66_00910	COG3842	ATPase activity
DKK66_00915	COG1177	transmembrane transport
DKK66_00930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DKK66_00935	COG0583	DNA-binding transcription factor activity
DKK66_00940	COG0473	3-isopropylmalate dehydrogenase activity
DKK66_00960	COG0640	Transcriptional regulator
DKK66_00965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DKK66_01005	COG0446	pyridine nucleotide-disulphide oxidoreductase
DKK66_01030	COG1538	Outer membrane efflux protein
DKK66_01040	COG2902	Dehydrogenase
DKK66_01055	COG4215	(ABC) transporter
DKK66_01075	COG4191	Histidine kinase
DKK66_01105	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DKK66_01130	COG0280	phosphate acetyltransferase
DKK66_01130	COG0281	malic enzyme
DKK66_01140	COG2990	Protein conserved in bacteria
DKK66_01145	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DKK66_01155	COG4178	(ABC) transporter
DKK66_01165	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DKK66_01165	COG1522	sequence-specific DNA binding
DKK66_01170	COG2313	pseudouridylate synthase activity
DKK66_01175	COG1418	mRNA catabolic process
DKK66_01190	COG2011	ABC-type metal ion transport system permease component
DKK66_01195	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DKK66_01215	COG0671	phosphoesterase, PA-phosphatase related
DKK66_01220	COG2059	Chromate
DKK66_01230	COG4566	intracellular signal transduction
DKK66_01235	COG1511	domain protein
DKK66_01235	COG3264	Mechanosensitive ion channel
DKK66_01240	COG1136	(ABC) transporter
DKK66_01255	COG0791	NLP P60 protein
DKK66_01280	COG1595	DNA-templated transcription, initiation
DKK66_01295	COG1028	Short-chain dehydrogenase reductase Sdr
DKK66_01300	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DKK66_01310	COG1562	ergosterol biosynthetic process
DKK66_01345	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
DKK66_01365	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
DKK66_01370	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DKK66_01375	COG1376	ErfK ybiS ycfS ynhG family protein
DKK66_01380	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DKK66_01425	COG4735	regulation of single-species biofilm formation
DKK66_01460	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DKK66_01505	COG1012	belongs to the aldehyde dehydrogenase family
DKK66_01510	COG1177	transmembrane transport
DKK66_01515	COG1176	ABC-type spermidine putrescine transport system, permease component I
DKK66_01520	COG3842	ATPase activity
DKK66_01525	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DKK66_01530	COG0583	DNA-binding transcription factor activity
DKK66_01540	COG1530	ribonuclease E activity
DKK66_01550	COG0546	phosphoglycolate phosphatase activity
DKK66_01565	COG1360	Flagellar Motor Protein
DKK66_01575	COG0167	dihydroorotate dehydrogenase activity
DKK66_01585	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
DKK66_01590	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
DKK66_01600	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
DKK66_01605	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
DKK66_01610	COG4139	cobalamin transport
DKK66_01615	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DKK66_01620	COG2719	SpoVR family
DKK66_01625	COG2718	Belongs to the UPF0229 family
DKK66_01630	COG2766	serine protein kinase
DKK66_01650	COG1960	acyl-CoA dehydrogenase activity
DKK66_01655	COG1012	belongs to the aldehyde dehydrogenase family
DKK66_01675	COG3618	amidohydrolase
DKK66_01680	COG3254	rhamnose metabolic process
DKK66_01685	COG4948	Mandelate Racemase Muconate Lactonizing
DKK66_01695	COG3012	SEC-C Motif Domain Protein
DKK66_01695	COG3318	Belongs to the UPF0149 family
DKK66_01700	COG0318	PFAM AMP-dependent synthetase and ligase
DKK66_01710	COG1960	acyl-CoA dehydrogenase activity
DKK66_01715	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DKK66_01740	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DKK66_01755	COG0254	rRNA binding
DKK66_01760	COG0215	cysteine-tRNA ligase activity
DKK66_01765	COG0205	6-phosphofructokinase activity
DKK66_01770	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DKK66_01780	COG1032	radical SAM domain protein
DKK66_01785	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DKK66_01790	COG0659	secondary active sulfate transmembrane transporter activity
DKK66_01810	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DKK66_01815	COG0840	transmembrane signaling receptor activity
DKK66_01820	COG1620	l-lactate permease
DKK66_01825	COG0246	Mannitol dehydrogenase
DKK66_01830	COG0477	Major facilitator Superfamily
DKK66_01835	COG1063	alcohol dehydrogenase
DKK66_01840	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
DKK66_01850	COG0583	DNA-binding transcription factor activity
DKK66_01855	COG3162	membrane
DKK66_01865	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DKK66_01870	COG3781	membrane
DKK66_01890	COG2878	Part of a membrane complex involved in electron transport
DKK66_01895	COG4656	Part of a membrane complex involved in electron transport
DKK66_01900	COG4658	electron transport chain
DKK66_01905	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
DKK66_01910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DKK66_01915	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
DKK66_01925	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
DKK66_01930	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
DKK66_01935	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
DKK66_01950	COG0617	tRNA 3'-terminal CCA addition
DKK66_01965	COG0534	Mate efflux family protein
DKK66_01970	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DKK66_01995	COG3706	GGDEF domain
DKK66_01995	COG0745	RESPONSE REGULATOR receiver
DKK66_02010	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
DKK66_02020	COG4172	Belongs to the ABC transporter superfamily
DKK66_02025	COG4239	(ABC) transporter, permease
DKK66_02030	COG4174	ABC transporter (Permease)
DKK66_02050	COG1028	Short-chain dehydrogenase reductase Sdr
DKK66_02060	COG1846	Transcriptional regulator
DKK66_02070	COG1113	amino acid transport
DKK66_02085	COG1012	belongs to the aldehyde dehydrogenase family
DKK66_02090	COG2207	Transcriptional regulator
DKK66_02110	COG1012	belongs to the aldehyde dehydrogenase family
DKK66_02115	COG3384	dioxygenase
DKK66_02125	COG2814	Major facilitator Superfamily
DKK66_02135	COG3971	2-oxopent-4-enoate hydratase activity
DKK66_02155	COG1960	acyl-CoA dehydrogenase activity
DKK66_02160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DKK66_02180	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DKK66_02195	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
DKK66_02205	COG2204	response regulator
DKK66_02215	COG2205	protein histidine kinase activity
DKK66_02245	COG0557	exoribonuclease II activity
DKK66_02265	COG0477	Major facilitator Superfamily
DKK66_02275	COG1858	cytochrome C peroxidase
DKK66_02285	COG0673	inositol 2-dehydrogenase activity
DKK66_02290	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
DKK66_02295	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
DKK66_02300	COG0330	HflC and HflK could
DKK66_02305	COG0330	HflC and HflK could
DKK66_02310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DKK66_02315	COG1923	regulation of RNA biosynthetic process
DKK66_02320	COG1160	GTP binding
DKK66_02335	COG0124	histidyl-tRNA synthetase
DKK66_02340	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
DKK66_02345	COG1426	Protein conserved in bacteria
DKK66_02355	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DKK66_02360	COG0105	UTP biosynthetic process
DKK66_02375	COG3718	enzyme involved in inositol metabolism
DKK66_02400	COG1172	Belongs to the binding-protein-dependent transport system permease family
DKK66_02405	COG1129	ABC transporter
DKK66_02420	COG3962	Belongs to the TPP enzyme family
DKK66_02425	COG1609	Transcriptional regulator
DKK66_02430	COG1082	Xylose isomerase domain protein TIM barrel
DKK66_02440	COG0673	inositol 2-dehydrogenase activity
DKK66_02455	COG0673	inositol 2-dehydrogenase activity
DKK66_02460	COG0673	inositol 2-dehydrogenase activity
DKK66_02480	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKK66_02485	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DKK66_02510	COG2974	May be involved in recombination
DKK66_02515	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
DKK66_02520	COG3384	dioxygenase
DKK66_02530	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
DKK66_02540	COG0717	Belongs to the dCTP deaminase family
DKK66_02550	COG3012	SEC-C Motif Domain Protein
DKK66_02565	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DKK66_02570	COG1929	Belongs to the glycerate kinase type-1 family
DKK66_02585	COG1448	Aminotransferase
DKK66_02610	COG3188	usher protein
DKK66_02645	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DKK66_02650	COG0322	excinuclease ABC activity
DKK66_02670	COG0596	Alpha beta hydrolase
DKK66_02680	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
DKK66_02690	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DKK66_02690	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
DKK66_02695	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DKK66_02700	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
DKK66_02710	COG0625	glutathione transferase activity
DKK66_02715	COG0129	dihydroxy-acid dehydratase activity
DKK66_02720	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
DKK66_02725	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
DKK66_02735	COG3639	organic phosphonate transmembrane transporter activity
DKK66_02740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKK66_02745	COG0765	amino acid transport
DKK66_02750	COG0765	amino acid transport
DKK66_02770	COG2217	Heavy metal translocating P-type atpase
DKK66_02775	COG0598	Magnesium transport protein CorA
DKK66_02780	COG0248	Ppx GppA phosphatase
DKK66_02785	COG0704	Plays a role in the regulation of phosphate uptake
DKK66_02790	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
DKK66_02795	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
DKK66_02800	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
DKK66_02810	COG0328	RNA-DNA hybrid ribonuclease activity
DKK66_02815	COG2226	methyltransferase
DKK66_02820	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKK66_02825	COG0741	lytic transglycosylase activity
DKK66_02825	COG1388	LysM domain
DKK66_02830	COG1490	D-aminoacyl-tRNA deacylase activity
DKK66_02835	COG0384	phenazine biosynthesis protein PhzF
DKK66_02840	COG3022	response to hydroperoxide
DKK66_02845	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DKK66_02865	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DKK66_02865	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DKK66_02875	COG0489	protein tyrosine kinase activity
DKK66_02890	COG2732	(Barnase) inhibitor
DKK66_02895	COG0436	Aminotransferase
DKK66_02910	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DKK66_02910	COG2169	Transcriptional regulator
DKK66_02915	COG3145	DNA-N1-methyladenine dioxygenase activity
DKK66_02920	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DKK66_02925	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DKK66_02935	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
DKK66_02950	COG0308	aminopeptidase N
DKK66_02960	COG3278	Belongs to the heme-copper respiratory oxidase family
DKK66_02975	COG2010	Cytochrome c
DKK66_02980	COG0348	domain, Protein
DKK66_02995	COG3033	Beta-eliminating lyase
DKK66_03000	COG3104	oligopeptide transport
DKK66_03010	COG0463	Glycosyl transferase, family 2
DKK66_03025	COG0564	pseudouridine synthase activity
DKK66_03030	COG1607	acyl-coa hydrolase
DKK66_03040	COG1346	cytolysis
DKK66_03045	COG1380	Effector of murein hydrolase LrgA
DKK66_03050	COG0583	DNA-binding transcription factor activity
DKK66_03070	COG0045	succinate-CoA ligase (ADP-forming) activity
DKK66_03075	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DKK66_03085	COG0508	dehydrogenase complex catalyzes the overall conversion of
DKK66_03090	COG0567	Dehydrogenase, E1 component
DKK66_03100	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
DKK66_03105	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
DKK66_03110	COG1053	succinate dehydrogenase
DKK66_03120	COG2009	succinate dehydrogenase
DKK66_03130	COG0039	L-malate dehydrogenase activity
DKK66_03140	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DKK66_03150	COG0402	S-adenosylhomocysteine deaminase activity
DKK66_03155	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
DKK66_03170	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
DKK66_03175	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DKK66_03180	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DKK66_03195	COG1191	sigma factor activity
DKK66_03200	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
DKK66_03205	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
DKK66_03205	COG1199	ATP-dependent helicase activity
DKK66_03230	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
DKK66_03235	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DKK66_03245	COG0583	DNA-binding transcription factor activity
DKK66_03260	COG0850	regulation of cytokinetic process
DKK66_03270	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
DKK66_03275	COG0583	DNA-binding transcription factor activity
DKK66_03280	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DKK66_03300	COG1187	pseudouridine synthase activity
DKK66_03305	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DKK66_03315	COG0583	DNA-binding transcription factor activity
DKK66_03330	COG0180	Tryptophanyl-tRNA synthetase
DKK66_03335	COG1994	Peptidase M50
DKK66_03340	COG0009	L-threonylcarbamoyladenylate synthase
DKK66_03345	COG0613	PHP domain protein
DKK66_03365	COG0252	asparaginase activity
DKK66_03380	COG2188	Transcriptional regulator
DKK66_03400	COG3842	ATPase activity
DKK66_03415	COG0861	Integral membrane protein TerC family
DKK66_03420	COG1914	H( )-stimulated, divalent metal cation uptake system
DKK66_03425	COG0330	HflC and HflK could
DKK66_03430	COG0330	HflC and HflK could
DKK66_03445	COG0583	DNA-binding transcription factor activity
DKK66_03480	COG0154	amidase activity
DKK66_03490	COG2957	Belongs to the agmatine deiminase family
DKK66_03515	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
DKK66_03525	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
DKK66_03530	COG1137	ATPase activity
DKK66_03535	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
DKK66_03540	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DKK66_03550	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
DKK66_03555	COG1660	Displays ATPase and GTPase activities
DKK66_03565	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
DKK66_03565	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
DKK66_03575	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKK66_03575	COG4191	Histidine kinase
DKK66_03580	COG3437	response regulator, receiver
DKK66_03580	COG0784	Response regulator, receiver
DKK66_03585	COG1272	protein, Hemolysin III
DKK66_03590	COG0563	adenylate kinase activity
DKK66_03595	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
DKK66_03600	COG2835	tetraacyldisaccharide 4'-kinase activity
DKK66_03605	COG1663	tetraacyldisaccharide 4'-kinase activity
DKK66_03610	COG0848	biopolymer transport protein
DKK66_03615	COG0811	peptide transport
DKK66_03620	COG1570	exodeoxyribonuclease VII activity
DKK66_03630	COG0640	Transcriptional regulator
DKK66_03635	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
DKK66_03640	COG4942	peptidase
DKK66_03645	COG0793	Belongs to the peptidase S41A family
DKK66_03650	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DKK66_03650	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
DKK66_03655	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
DKK66_03670	COG0488	(ABC) transporter
DKK66_03680	COG4942	peptidase
DKK66_03685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DKK66_03715	COG0527	aspartate kinase activity
DKK66_03720	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
DKK66_03725	COG3383	formate dehydrogenase (NAD+) activity
DKK66_03725	COG0243	molybdopterin cofactor binding
DKK66_03730	COG0243	molybdopterin cofactor binding
DKK66_03730	COG3383	formate dehydrogenase (NAD+) activity
DKK66_03735	COG0437	4 iron, 4 sulfur cluster binding
DKK66_03740	COG2864	formate dehydrogenase
DKK66_03760	COG0643	Histidine kinase
DKK66_03760	COG2198	Histidine kinase
DKK66_03780	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DKK66_03785	COG2201	protein-glutamate methylesterase activity
DKK66_03790	COG3706	GGDEF domain
DKK66_03790	COG2203	Gaf domain
DKK66_03790	COG5001	Diguanylate cyclase
DKK66_03790	COG4251	negative regulation of phosphorylation
DKK66_03795	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
DKK66_03805	COG1921	L-seryl-tRNASec selenium transferase activity
DKK66_03820	COG3276	selenocysteine insertion sequence binding
DKK66_03840	COG0247	lactate metabolic process
DKK66_03845	COG1139	Iron-sulfur cluster binding protein
DKK66_03855	COG0513	Belongs to the DEAD box helicase family
DKK66_03860	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DKK66_03895	COG0436	Aminotransferase
DKK66_03905	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DKK66_03915	COG2610	gluconate transmembrane transporter activity
DKK66_03920	COG1028	Short-chain dehydrogenase reductase Sdr
DKK66_03935	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
DKK66_03950	COG2226	methyltransferase
DKK66_03960	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
DKK66_03965	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DKK66_03970	COG0511	ligase activity, forming carbon-carbon bonds
DKK66_03975	COG0439	Biotin carboxylase
DKK66_03980	COG2264	protein methyltransferase activity
DKK66_04000	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
DKK66_04010	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
DKK66_04025	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
DKK66_04030	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
DKK66_04045	COG2059	Chromate
DKK66_04050	COG0583	DNA-binding transcription factor activity
DKK66_04070	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
DKK66_04085	COG0019	diaminopimelate decarboxylase activity
DKK66_04090	COG0583	DNA-binding transcription factor activity
DKK66_04095	COG0840	transmembrane signaling receptor activity
DKK66_04115	COG1301	dicarboxylic acid transport
DKK66_04135	COG0828	Belongs to the bacterial ribosomal protein bS21 family
DKK66_04140	COG2022	thiamine diphosphate biosynthetic process
DKK66_04150	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DKK66_04155	COG1758	RNA polymerase activity
DKK66_04160	COG0194	GDP metabolic process
DKK66_04165	COG2252	PERMEase
DKK66_04170	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
DKK66_04180	COG1695	Transcriptional regulator
DKK66_04195	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DKK66_04200	COG2235	arginine
DKK66_04215	COG0543	2 iron, 2 sulfur cluster binding
DKK66_04215	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DKK66_04225	COG0220	tRNA (guanine-N7-)-methyltransferase activity
DKK66_04230	COG0386	Belongs to the glutathione peroxidase family
DKK66_04240	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
DKK66_04255	COG0586	Pfam SNARE associated Golgi protein
DKK66_04260	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DKK66_04265	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
DKK66_04275	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DKK66_04280	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
DKK66_04285	COG1534	Rna-binding protein
DKK66_04315	COG1960	acyl-CoA dehydrogenase activity
DKK66_04330	COG2030	dehydratase
DKK66_04345	COG0802	atpase or kinase
DKK66_04350	COG0860	N-Acetylmuramoyl-L-alanine amidase
DKK66_04355	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
DKK66_04360	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
DKK66_04365	COG0237	dephospho-CoA kinase activity
DKK66_04370	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
DKK66_04390	COG0415	Belongs to the DNA photolyase family
DKK66_04395	COG1555	photosystem II stabilization
DKK66_04395	COG1596	polysaccharide export
DKK66_04400	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DKK66_04405	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
DKK66_04425	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
DKK66_04445	COG0347	Belongs to the P(II) protein family
DKK66_04450	COG0004	ammonium transporteR
DKK66_04455	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
DKK66_04465	COG1560	Kdo2-lipid A biosynthetic process
DKK66_04475	COG1007	ATP synthesis coupled electron transport
DKK66_04490	COG0713	ATP synthesis coupled electron transport
DKK66_04500	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DKK66_04505	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
DKK66_04510	COG1034	ATP synthesis coupled electron transport
DKK66_04520	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
DKK66_04525	COG0649	NAD binding
DKK66_04530	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DKK66_04535	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DKK66_04540	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
DKK66_04550	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DKK66_04555	COG0149	triose-phosphate isomerase activity
DKK66_04575	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
DKK66_04580	COG0306	phosphate transporter
DKK66_04585	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
DKK66_04610	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
DKK66_04615	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
DKK66_04620	COG0109	protoheme IX farnesyltransferase activity
DKK66_04640	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
DKK66_04645	COG0840	transmembrane signaling receptor activity
DKK66_04650	COG0745	RESPONSE REGULATOR receiver
DKK66_04655	COG2205	protein histidine kinase activity
DKK66_04665	COG3591	Belongs to the peptidase S1B family
DKK66_04670	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
DKK66_04675	COG0631	protein serine/threonine phosphatase activity
DKK66_04680	COG1357	PFAM Pentapeptide repeats (8 copies)
DKK66_04680	COG0515	serine threonine protein kinase
DKK66_04685	COG1561	YicC-like family, N-terminal region
DKK66_04705	COG3813	Protein conserved in bacteria
DKK66_04710	COG2084	Dehydrogenase
DKK66_04715	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
DKK66_04750	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DKK66_04755	COG1216	Glycosyl transferase, family 2
DKK66_04755	COG0438	transferase activity, transferring glycosyl groups
DKK66_04760	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DKK66_04780	COG1012	belongs to the aldehyde dehydrogenase family
DKK66_04785	COG0318	PFAM AMP-dependent synthetase and ligase
DKK66_04805	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
DKK66_04810	COG1678	Uncharacterized ACR, COG1678
DKK66_04820	COG2223	nitrite transmembrane transporter activity
DKK66_04835	COG1210	Utp--glucose-1-phosphate uridylyltransferase
DKK66_04845	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
DKK66_04855	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DKK66_04860	COG1846	Transcriptional regulator
DKK66_04865	COG3038	cytochrome b561
DKK66_04870	COG2353	YceI-like domain
DKK66_04885	COG0477	Major facilitator Superfamily
DKK66_04890	COG1161	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity
DKK66_04925	COG1414	Transcriptional regulator
DKK66_04935	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
DKK66_04950	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DKK66_04955	COG1538	Outer membrane efflux protein
DKK66_04960	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DKK66_05025	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
DKK66_05030	COG0514	ATP-dependent DNA helicase (RecQ)
DKK66_05040	COG1192	Involved in chromosome partitioning
DKK66_05045	COG2205	protein histidine kinase activity
DKK66_05050	COG0745	RESPONSE REGULATOR receiver
DKK66_05050	COG3706	GGDEF domain
DKK66_05060	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
DKK66_05075	COG2900	Belongs to the SlyX family
DKK66_05095	COG2171	N-acyltransferase activity
DKK66_05100	COG1127	ABC transporter
DKK66_05105	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
DKK66_05110	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
DKK66_05125	COG2853	Lipoprotein
DKK66_05130	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DKK66_05140	COG0842	Transport permease protein
DKK66_05145	COG1131	(ABC) transporter
DKK66_05185	COG3047	cAMP biosynthetic process
DKK66_05190	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
DKK66_05195	COG3171	Protein conserved in bacteria
DKK66_05215	COG1027	Aspartate ammonia-lyase
DKK66_05220	COG0406	alpha-ribazole phosphatase activity
DKK66_05225	COG0583	DNA-binding transcription factor activity
DKK66_05230	COG3706	GGDEF domain
DKK66_05240	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DKK66_05245	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
DKK66_05270	COG0297	glycogen (starch) synthase activity
DKK66_05315	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
DKK66_05320	COG0037	tRNA processing
DKK66_05325	COG1028	Short-chain dehydrogenase reductase Sdr
DKK66_05350	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DKK66_05355	COG1187	pseudouridine synthase activity
DKK66_05375	COG1879	ABC-type sugar transport system periplasmic component
DKK66_05380	COG1172	Belongs to the binding-protein-dependent transport system permease family
DKK66_05385	COG1129	ABC transporter
DKK66_05390	COG1869	D-ribose catabolic process
DKK66_05395	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DKK66_05410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DKK66_05425	COG1702	phosphate starvation-inducible protein PhoH
DKK66_05430	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
DKK66_05435	COG4535	Mg2 and Co2 transporter CorC
DKK66_05440	COG0815	Transfers the fatty acyl group on membrane lipoproteins
DKK66_05445	COG0840	transmembrane signaling receptor activity
DKK66_05450	COG3217	Mosc domain protein beta barrel domain protein
DKK66_05450	COG0633	Ferredoxin
DKK66_05455	COG0203	ribosomal protein L17
DKK66_05460	COG0202	RNA polymerase activity
DKK66_05465	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
DKK66_05470	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
DKK66_05475	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
DKK66_05480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
DKK66_05485	COG0201	protein transport
DKK66_05490	COG0200	Binds to the 23S rRNA
DKK66_05495	COG1841	ribosomal large subunit assembly
DKK66_05500	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
DKK66_05505	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
DKK66_05510	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
DKK66_05515	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
DKK66_05520	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
DKK66_05525	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
DKK66_05530	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
DKK66_05535	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
DKK66_05540	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
DKK66_05545	COG0255	Belongs to the universal ribosomal protein uL29 family
DKK66_05550	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
DKK66_05555	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
DKK66_05560	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
DKK66_05565	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
DKK66_05570	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
DKK66_05575	COG0089	rRNA binding
DKK66_05580	COG0088	Forms part of the polypeptide exit tunnel
DKK66_05585	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
DKK66_05590	COG0051	transcription antitermination factor activity, RNA binding
DKK66_05595	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DKK66_05600	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
DKK66_05605	COG0049	tRNA binding
DKK66_05610	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
DKK66_05615	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
DKK66_05620	COG0085	RNA polymerase activity
DKK66_05625	COG0222	ribosome binding
DKK66_05630	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
DKK66_05640	COG0081	regulation of translation
DKK66_05645	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
DKK66_05665	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
DKK66_05685	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
DKK66_05690	COG0742	ribosomal rna small subunit methyltransferase
DKK66_05700	COG0612	Peptidase, M16
DKK66_05710	COG2884	Cell division ATP-binding protein ftsE
DKK66_05720	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DKK66_05725	COG3307	-O-antigen
DKK66_05740	COG4969	Belongs to the N-Me-Phe pilin family
DKK66_05755	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
DKK66_05770	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DKK66_05770	COG0519	Catalyzes the synthesis of GMP from XMP
DKK66_05775	COG2255	four-way junction helicase activity
DKK66_05780	COG0632	four-way junction helicase activity
DKK66_05790	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
DKK66_05795	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DKK66_05805	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
DKK66_05810	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DKK66_05815	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
DKK66_05825	COG0625	glutathione transferase activity
DKK66_05835	COG1253	flavin adenine dinucleotide binding
DKK66_05860	COG0708	Exodeoxyribonuclease III
DKK66_05865	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
DKK66_05900	COG1324	tolerance protein
DKK66_05910	COG1872	DUF167
DKK66_05915	COG0783	Belongs to the Dps family
DKK66_05930	COG0824	Thioesterase
DKK66_05935	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DKK66_05940	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DKK66_05945	COG2204	response regulator
DKK66_05950	COG5000	phosphorelay sensor kinase activity
DKK66_05965	COG0501	Belongs to the peptidase M48B family
DKK66_05970	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DKK66_05975	COG0242	peptide deformylase activity
DKK66_05985	COG0758	DNA mediated transformation
DKK66_05990	COG2922	Belongs to the Smg family
DKK66_06020	COG0189	ligase activity
DKK66_06040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DKK66_06045	COG0446	pyridine nucleotide-disulphide oxidoreductase
DKK66_06045	COG1902	pentaerythritol trinitrate reductase activity
DKK66_06055	COG2267	carboxylic ester hydrolase activity
DKK66_06060	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DKK66_06065	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
DKK66_06070	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DKK66_06085	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
DKK66_06090	COG2885	chlorophyll binding
DKK66_06095	COG0823	Involved in the tonB-independent uptake of proteins
DKK66_06135	COG0210	DNA helicase
DKK66_06150	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DKK66_06170	COG1045	serine acetyltransferase
DKK66_06175	COG1530	ribonuclease E activity
DKK66_06180	COG0424	maF-like protein
DKK66_06185	COG0653	protein targeting
DKK66_06195	COG1116	anion transmembrane transporter activity
DKK66_06210	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
DKK66_06215	COG4208	sulfate ABC transporter
DKK66_06235	COG0840	transmembrane signaling receptor activity
DKK66_06240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
DKK66_06260	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
DKK66_06290	COG0174	glutamine synthetase
DKK66_06295	COG0405	Gamma-glutamyltransferase
DKK66_06305	COG0589	response to stress
DKK66_06315	COG3132	Protein of unknown function, DUF480
DKK66_06335	COG1505	serine-type exopeptidase activity
DKK66_06360	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
DKK66_06365	COG0501	Belongs to the peptidase M48B family
DKK66_06370	COG4608	Belongs to the ABC transporter superfamily
DKK66_06380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DKK66_06385	COG0601	transmembrane transport
DKK66_06390	COG4166	transmembrane transport
DKK66_06395	COG0418	dihydroorotase activity
DKK66_06425	COG0315	cyclic pyranopterin monophosphate synthase activity
DKK66_06435	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
DKK66_06450	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
DKK66_06455	COG1181	Belongs to the D-alanine--D-alanine ligase family
DKK66_06460	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DKK66_06465	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
DKK66_06470	COG0772	Belongs to the SEDS family
DKK66_06475	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
DKK66_06480	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DKK66_06485	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DKK66_06490	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
DKK66_06500	COG3116	cell division
DKK66_06505	COG0275	rRNA processing
DKK66_06510	COG2001	Belongs to the MraZ family
DKK66_06515	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DKK66_06520	COG0154	amidase activity
DKK66_06525	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
DKK66_06530	COG1077	Cell shape determining protein MreB Mrl
DKK66_06535	COG1792	Involved in formation and maintenance of cell shape
DKK66_06540	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
DKK66_06545	COG0768	penicillin binding
DKK66_06550	COG0772	Belongs to the SEDS family
DKK66_06565	COG3791	Glutathione-dependent formaldehyde-activating
DKK66_06580	COG2847	Copper chaperone PCu(A)C
DKK66_06590	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DKK66_06595	COG0625	glutathione transferase activity
DKK66_06600	COG1752	Esterase of the alpha-beta hydrolase superfamily
DKK66_06605	COG2226	methyltransferase
DKK66_06610	COG2267	carboxylic ester hydrolase activity
DKK66_06615	COG5001	Diguanylate cyclase
DKK66_06615	COG3300	MHYT domain
DKK66_06620	COG0156	8-amino-7-oxononanoate synthase activity
DKK66_06625	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
DKK66_06630	COG1040	competence protein
DKK66_06635	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DKK66_06645	COG0218	Necessary for normal cell division and for the maintenance of normal septation
DKK66_06655	COG1333	cytochrome c biogenesis protein
DKK66_06660	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
DKK66_06665	COG1253	flavin adenine dinucleotide binding
DKK66_06680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKK66_06695	COG0166	Belongs to the GPI family
DKK66_06705	COG0837	glucose binding
DKK66_06715	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
DKK66_06720	COG0129	dihydroxy-acid dehydratase activity
DKK66_06725	COG0800	Aldolase
DKK66_06730	COG0745	RESPONSE REGULATOR receiver
DKK66_06735	COG5002	protein histidine kinase activity
DKK66_06750	COG0395	ABC-type sugar transport system, permease component
DKK66_06755	COG3842	ATPase activity
DKK66_06760	COG4989	oxidoreductase activity
DKK66_06770	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
DKK66_06775	COG0745	RESPONSE REGULATOR receiver
DKK66_06775	COG3706	GGDEF domain
DKK66_06785	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
DKK66_06790	COG2200	EAL domain
DKK66_06795	COG0165	Argininosuccinate lyase
DKK66_06810	COG3275	phosphorelay sensor kinase activity
DKK66_06825	COG0446	pyridine nucleotide-disulphide oxidoreductase
DKK66_06825	COG1902	pentaerythritol trinitrate reductase activity
DKK66_06845	COG0028	Belongs to the TPP enzyme family
DKK66_06850	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DKK66_06855	COG0181	hydroxymethylbilane synthase activity
DKK66_06865	COG2959	enzyme of heme biosynthesis
DKK66_06880	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
DKK66_06885	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DKK66_06890	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DKK66_06900	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
DKK66_06905	COG0706	membrane insertase activity
DKK66_06910	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
DKK66_06915	COG0594	ribonuclease P activity
DKK66_06920	COG0230	Belongs to the bacterial ribosomal protein bL34 family
DKK66_06925	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DKK66_06940	COG5002	protein histidine kinase activity
DKK66_06980	COG2197	response regulator
DKK66_06995	COG0438	transferase activity, transferring glycosyl groups
DKK66_07005	COG3177	Filamentation induced by cAMP protein fic
DKK66_07010	COG3177	Filamentation induced by cAMP protein fic
DKK66_07085	COG2066	Belongs to the glutaminase family
DKK66_07105	COG1858	cytochrome C peroxidase
DKK66_07130	COG5001	Diguanylate cyclase
DKK66_07130	COG4251	negative regulation of phosphorylation
DKK66_07130	COG3706	GGDEF domain
DKK66_07130	COG2203	Gaf domain
DKK66_07140	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DKK66_07150	COG0583	DNA-binding transcription factor activity
DKK66_07160	COG1132	(ABC) transporter
DKK66_07210	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DKK66_07215	COG4569	acetaldehyde dehydrogenase (acetylating) activity
DKK66_07220	COG3971	2-oxopent-4-enoate hydratase activity
DKK66_07225	COG0583	DNA-binding transcription factor activity
DKK66_07240	COG0583	DNA-binding transcription factor activity
DKK66_07245	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
DKK66_07275	COG0259	pyridoxamine-phosphate oxidase activity
DKK66_07280	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
DKK66_07285	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
DKK66_07290	COG0583	DNA-binding transcription factor activity
DKK66_07300	COG2201	protein-glutamate methylesterase activity
DKK66_07355	COG2153	protein acetylation
DKK66_07365	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
DKK66_07370	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DKK66_07375	COG0126	phosphoglycerate kinase activity
DKK66_07380	COG1280	lysine exporter protein (LysE YggA)
DKK66_07390	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
DKK66_07395	COG0314	molybdopterin synthase activity
DKK66_07400	COG0746	molybdenum cofactor guanylyltransferase activity
DKK66_07405	COG0583	DNA-binding transcription factor activity
DKK66_07415	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DKK66_07420	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
DKK66_07425	COG4654	Cytochrome c, class I
DKK66_07430	COG0762	integral membrane protein
DKK66_07460	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DKK66_07465	COG1126	abc transporter atp-binding protein
DKK66_07470	COG0765	amino acid transport
DKK66_07475	COG0765	amino acid transport
DKK66_07480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKK66_07485	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DKK66_07490	COG1238	metal cluster binding
DKK66_07495	COG1965	Belongs to the frataxin family
DKK66_07500	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DKK66_07515	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
DKK66_07520	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DKK66_07535	COG4783	chaperone-mediated protein folding
DKK66_07540	COG1773	rubredoxin
DKK66_07545	COG0351	phosphomethylpyrimidine kinase
DKK66_07550	COG0352	thiamine-phosphate diphosphorylase activity
DKK66_07565	COG0842	Transport permease protein
DKK66_07570	COG0842	Transport permease protein
DKK66_07575	COG1131	(ABC) transporter
DKK66_07580	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKK66_07590	COG1519	Transferase
DKK66_07595	COG0859	PFAM glycosyl transferase family 9
DKK66_07615	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DKK66_07615	COG4651	solute:proton antiporter activity
DKK66_07620	COG1253	flavin adenine dinucleotide binding
DKK66_07625	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
DKK66_07635	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DKK66_07640	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
DKK66_07655	COG3214	Protein conserved in bacteria
DKK66_07670	COG0826	peptidase U32
DKK66_07700	COG4628	conserved protein (DUF2132)
DKK66_07715	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DKK66_07720	COG0668	transmembrane transport
DKK66_07740	COG0540	Belongs to the ATCase OTCase family
DKK66_07745	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
DKK66_07750	COG1247	-acetyltransferase
DKK66_07815	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DKK66_07825	COG0676	glucose-6-phosphate 1-epimerase activity
DKK66_07830	COG2188	Transcriptional regulator
DKK66_07835	COG1968	undecaprenyl-diphosphatase activity
DKK66_07840	COG1228	amidohydrolase
DKK66_07845	COG0010	Belongs to the arginase family
DKK66_07850	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
DKK66_07855	COG2986	histidine ammonia-lyase
DKK66_07860	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DKK66_07895	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
DKK66_07900	COG2267	carboxylic ester hydrolase activity
DKK66_07910	COG0469	pyruvate kinase activity
DKK66_07915	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
DKK66_07920	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DKK66_07955	COG0579	oxidoreductase
DKK66_07960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DKK66_07965	COG3135	benzoate transporter
DKK66_07975	COG2707	UPF0756 membrane protein
DKK66_07980	COG0006	proline dipeptidase activity
DKK66_07990	COG1522	sequence-specific DNA binding
DKK66_07995	COG0697	spore germination
DKK66_08025	COG3842	ATPase activity
DKK66_08030	COG1176	ABC-type spermidine putrescine transport system, permease component I
DKK66_08035	COG1177	transmembrane transport
DKK66_08040	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DKK66_08050	COG0069	glutamate synthase activity
DKK66_08065	COG2205	protein histidine kinase activity
DKK66_08070	COG0745	RESPONSE REGULATOR receiver
DKK66_08105	COG3150	esterase
DKK66_08115	COG1410	methionine synthase
DKK66_08115	COG0646	methionine synthase
DKK66_08120	COG2203	Gaf domain
DKK66_08120	COG2199	diguanylate cyclase activity
DKK66_08125	COG2841	Protein conserved in bacteria
DKK66_08130	COG1132	(ABC) transporter
DKK66_08135	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
DKK66_08140	COG2199	diguanylate cyclase activity
DKK66_08140	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DKK66_08155	COG1451	nucleotide metabolic process
DKK66_08165	COG1522	sequence-specific DNA binding
DKK66_08175	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DKK66_08185	COG4681	YaeQ
DKK66_08195	COG0513	Belongs to the DEAD box helicase family
DKK66_08210	COG3706	GGDEF domain
DKK66_08215	COG0745	RESPONSE REGULATOR receiver
DKK66_08215	COG3706	GGDEF domain
DKK66_08240	COG0783	Belongs to the Dps family
DKK66_08245	COG0840	transmembrane signaling receptor activity
DKK66_08250	COG0840	transmembrane signaling receptor activity
DKK66_08255	COG3128	pkhd-type hydroxylase
DKK66_08260	COG4774	siderophore transport
DKK66_08280	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
DKK66_08285	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
DKK66_08340	COG4968	Prepilin-type N-terminal cleavage methylation domain
DKK66_08345	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DKK66_08355	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
DKK66_08385	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
DKK66_08395	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
DKK66_08410	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DKK66_08425	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DKK66_08440	COG0495	leucyl-tRNA aminoacylation
DKK66_08450	COG1466	dna polymerase III delta subunit
DKK66_08460	COG1196	nuclear chromosome segregation
DKK66_08460	COG0741	lytic transglycosylase activity
DKK66_08460	COG0739	heme binding
DKK66_08465	COG3753	Protein conserved in bacteria
DKK66_08470	COG0450	alkyl hydroperoxide reductase
DKK66_08490	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
DKK66_08495	COG0799	negative regulation of ribosome biogenesis
DKK66_08500	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DKK66_08505	COG0288	reversible hydration of carbon dioxide
DKK66_08525	COG0640	Transcriptional regulator
DKK66_08530	COG2391	methyltransferase activity
DKK66_08545	COG4783	chaperone-mediated protein folding
DKK66_08555	COG0508	dehydrogenase complex catalyzes the overall conversion of
DKK66_08560	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DKK66_08575	COG1473	amidohydrolase
DKK66_08580	COG1957	nucleoside hydrolase
DKK66_08610	COG0138	bifunctional purine biosynthesis protein purh
DKK66_08630	COG0009	L-threonylcarbamoyladenylate synthase
DKK66_08640	COG0697	spore germination
DKK66_08645	COG2188	Transcriptional regulator
DKK66_08650	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
DKK66_08655	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DKK66_08660	COG2190	(PTS) system
DKK66_08660	COG1263	PTS System
DKK66_08660	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DKK66_08665	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
DKK66_08670	COG1522	sequence-specific DNA binding
DKK66_08675	COG0745	RESPONSE REGULATOR receiver
DKK66_08680	COG5002	protein histidine kinase activity
DKK66_08690	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DKK66_08695	COG3945	hemerythrin HHE cation binding domain
DKK66_08705	COG3158	transport of potassium into the cell
DKK66_08710	COG0442	prolyl-tRNA aminoacylation
DKK66_08715	COG0741	lytic transglycosylase activity
DKK66_08720	COG1914	H( )-stimulated, divalent metal cation uptake system
DKK66_08725	COG1846	Transcriptional regulator
DKK66_08750	COG0028	Belongs to the TPP enzyme family
DKK66_08755	COG0440	acetolactate synthase activity
DKK66_08760	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
DKK66_08765	COG1183	phosphatidylcholine synthase activity
DKK66_08770	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
DKK66_08775	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
DKK66_08790	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
DKK66_08830	COG1999	signal sequence binding
DKK66_08835	COG5581	Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility
DKK66_08840	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
DKK66_08845	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
DKK66_08850	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
DKK66_08855	COG0131	Imidazoleglycerol-phosphate dehydratase
DKK66_08860	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
DKK66_08865	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
DKK66_08870	COG0107	imidazoleglycerol-phosphate synthase activity
DKK66_08875	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
DKK66_08880	COG0140	phosphoribosyl-ATP diphosphatase activity
DKK66_08890	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DKK66_08895	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
DKK66_08915	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKK66_08940	COG1538	Outer membrane efflux protein
DKK66_08950	COG0084	hydrolase, TatD family'
DKK66_08980	COG2856	Zn peptidase
DKK66_09025	COG0582	viral genome integration into host DNA
DKK66_09045	COG0792	nuclease activity
DKK66_09050	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
DKK66_09055	COG2823	Periplasmic or secreted lipoprotein
DKK66_09060	COG4943	cyclic-guanylate-specific phosphodiesterase activity
DKK66_09070	COG1720	tRNA m6t6A37 methyltransferase activity
DKK66_09080	COG0445	tRNA wobble uridine modification
DKK66_09085	COG0357	Ribosomal RNA small subunit methyltransferase G
DKK66_09090	COG1192	Involved in chromosome partitioning
DKK66_09105	COG0356	it plays a direct role in the translocation of protons across the membrane
DKK66_09115	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
DKK66_09120	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
DKK66_09125	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
DKK66_09130	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
DKK66_09135	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
DKK66_09140	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DKK66_09145	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DKK66_09150	COG1349	DNA-binding transcription factor activity
DKK66_09155	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
DKK66_09185	COG0477	Major facilitator Superfamily
DKK66_09210	COG0583	DNA-binding transcription factor activity
DKK66_09215	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
DKK66_09220	COG5002	protein histidine kinase activity
DKK66_09220	COG5001	Diguanylate cyclase
DKK66_09220	COG3447	MASE1 domain protein
DKK66_09225	COG0408	coproporphyrinogen oxidase activity
DKK66_09235	COG2205	protein histidine kinase activity
DKK66_09240	COG0745	RESPONSE REGULATOR receiver
DKK66_09245	COG1966	Carbon starvation protein
DKK66_09250	COG2879	small protein
DKK66_09255	COG2855	membrane
DKK66_09260	COG0583	DNA-binding transcription factor activity
DKK66_09275	COG1611	Belongs to the LOG family
DKK66_09280	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DKK66_09280	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
DKK66_09340	COG2814	Major facilitator Superfamily
DKK66_09345	COG1566	PFAM secretion protein HlyD family protein
DKK66_09350	COG1538	Outer membrane efflux protein
DKK66_09355	COG1846	Transcriptional regulator
DKK66_09360	COG1393	Belongs to the ArsC family
DKK66_09395	COG2329	Antibiotic biosynthesis monooxygenase
DKK66_09405	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
DKK66_09410	COG1242	4 iron, 4 sulfur cluster binding
DKK66_09420	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DKK66_09425	COG2813	Specifically methylates the guanine in position
DKK66_09425	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
DKK66_09430	COG2814	Major facilitator Superfamily
DKK66_09440	COG2223	nitrite transmembrane transporter activity
DKK66_09445	COG2207	Transcriptional regulator
DKK66_09460	COG1959	2 iron, 2 sulfur cluster binding
DKK66_09460	COG1295	ribonuclease BN
DKK66_09475	COG1648	precorrin-2 dehydrogenase activity
DKK66_09475	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DKK66_09485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKK66_09490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DKK66_09495	COG0859	PFAM glycosyl transferase family 9
DKK66_09500	COG0438	transferase activity, transferring glycosyl groups
DKK66_09510	COG0438	transferase activity, transferring glycosyl groups
DKK66_09515	COG1132	(ABC) transporter
DKK66_09525	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
DKK66_09530	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
DKK66_09570	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DKK66_09580	COG1538	Outer membrane efflux protein
DKK66_09585	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
DKK66_09590	COG1283	sodium-dependent phosphate transmembrane transporter activity
DKK66_09595	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DKK66_09595	COG2755	lipolytic protein G-D-S-L family
DKK66_09610	COG0142	geranyltranstransferase activity
DKK66_09615	COG0261	This protein binds to 23S rRNA in the presence of protein L20
DKK66_09620	COG0211	Belongs to the bacterial ribosomal protein bL27 family
DKK66_09625	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
DKK66_09635	COG4215	(ABC) transporter
DKK66_09640	COG4160	amino acid transport
DKK66_09645	COG4598	ABC transporter
DKK66_09675	COG1196	nuclear chromosome segregation
DKK66_09685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
DKK66_09700	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
DKK66_09710	COG0840	transmembrane signaling receptor activity
DKK66_09725	COG3501	Rhs element vgr protein
DKK66_09745	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
DKK66_09750	COG0339	signal peptide processing
DKK66_09760	COG2194	sulfuric ester hydrolase activity
DKK66_09765	COG0708	Exodeoxyribonuclease III
DKK66_09770	COG2226	methyltransferase
DKK66_09785	COG0473	3-isopropylmalate dehydrogenase activity
DKK66_09790	COG0438	transferase activity, transferring glycosyl groups
DKK66_09800	COG0745	RESPONSE REGULATOR receiver
DKK66_09805	COG0642	Histidine kinase
DKK66_09855	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DKK66_09865	COG1012	belongs to the aldehyde dehydrogenase family
DKK66_09870	COG2197	response regulator
DKK66_09875	COG0583	DNA-binding transcription factor activity
DKK66_09900	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
DKK66_09905	COG1074	ATP-dependent DNA helicase activity
DKK66_09920	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DKK66_09935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKK66_09935	COG2205	protein histidine kinase activity
DKK66_09940	COG2193	ferroxidase activity
DKK66_09955	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DKK66_09995	COG3245	cytochrome
DKK66_10005	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
DKK66_10015	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DKK66_10025	COG3017	Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein
DKK66_10030	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
DKK66_10040	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
DKK66_10045	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
DKK66_10050	COG0193	aminoacyl-tRNA hydrolase activity
DKK66_10055	COG0012	GTP binding
DKK66_10080	COG1022	Amp-dependent synthetase and ligase
DKK66_10085	COG0626	cystathionine gamma-synthase activity
DKK66_10095	COG1982	Orn Lys Arg decarboxylase major
DKK66_10105	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DKK66_10110	COG0067	glutamate synthase
DKK66_10110	COG0069	glutamate synthase activity
DKK66_10110	COG0070	glutamate synthase
DKK66_10120	COG0493	'glutamate synthase
DKK66_10130	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DKK66_10130	COG0546	phosphoglycolate phosphatase activity
DKK66_10140	COG1028	Short-chain dehydrogenase reductase Sdr
DKK66_10185	COG1216	Glycosyl transferase, family 2
DKK66_10195	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DKK66_10215	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DKK66_10225	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
DKK66_10240	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DKK66_10250	COG0459	protein refolding
DKK66_10260	COG0723	plastoquinol--plastocyanin reductase activity
DKK66_10265	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
DKK66_10270	COG2857	Cytochrome c1
DKK66_10275	COG0625	glutathione transferase activity
DKK66_10280	COG2969	positive regulation of protein catabolic process
DKK66_10290	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
DKK66_10295	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DKK66_10300	COG5001	Diguanylate cyclase
DKK66_10300	COG4251	negative regulation of phosphorylation
DKK66_10300	COG3706	GGDEF domain
DKK66_10300	COG2203	Gaf domain
DKK66_10305	COG1879	ABC-type sugar transport system periplasmic component
DKK66_10310	COG1522	sequence-specific DNA binding
DKK66_10320	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
DKK66_10330	COG0625	glutathione transferase activity
DKK66_10345	COG0561	phosphatase activity
DKK66_10365	COG0583	DNA-binding transcription factor activity
DKK66_10370	COG1301	dicarboxylic acid transport
DKK66_10380	COG2095	MarC family integral membrane protein
DKK66_10390	COG1194	a g-specific adenine glycosylase
DKK66_10395	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DKK66_10405	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
DKK66_10410	COG0213	The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis
DKK66_10415	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
DKK66_10420	COG0813	purine-nucleoside phosphorylase activity
DKK66_10425	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
DKK66_10430	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
DKK66_10440	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
DKK66_10445	COG0316	Belongs to the HesB IscA family
DKK66_10455	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DKK66_10460	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
DKK66_10480	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
DKK66_10485	COG0123	including yeast histone deacetylase and acetoin utilization protein
DKK66_10490	COG0714	Associated with various cellular activities
DKK66_10505	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DKK66_10510	COG4942	peptidase
DKK66_10510	COG1388	LysM domain
DKK66_10515	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
DKK66_10520	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
DKK66_10525	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DKK66_10530	COG0045	succinate-CoA ligase (ADP-forming) activity
DKK66_10530	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
DKK66_10530	COG1042	CoA-binding domain protein
DKK66_10535	COG0228	four-way junction DNA binding
DKK66_10540	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
DKK66_10545	COG0336	Belongs to the RNA methyltransferase TrmD family
DKK66_10550	COG0335	large ribosomal subunit rRNA binding
DKK66_10555	COG4974	Belongs to the 'phage' integrase family
DKK66_10560	COG0542	response to heat
DKK66_10565	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
DKK66_10570	COG1278	Cold shock
DKK66_10575	COG0477	Major facilitator Superfamily
DKK66_10585	COG0538	isocitrate dehydrogenase activity
DKK66_10600	COG4579	[isocitrate dehydrogenase (NADP+)] phosphatase activity
DKK66_10615	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
DKK66_10625	COG1271	oxidase subunit
DKK66_10630	COG1294	oxidase, subunit
DKK66_10635	COG0584	glycerophosphoryl diester phosphodiesterase
DKK66_10640	COG4095	Psort location CytoplasmicMembrane, score
DKK66_10655	COG2814	Major facilitator Superfamily
DKK66_10665	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
DKK66_10680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DKK66_10685	COG0635	Involved in the biosynthesis of porphyrin-containing compound
DKK66_10690	COG1959	2 iron, 2 sulfur cluster binding
DKK66_10695	COG1017	nitric oxide dioxygenase activity
DKK66_10695	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DKK66_10715	COG1012	belongs to the aldehyde dehydrogenase family
DKK66_10770	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DKK66_10770	COG0446	pyridine nucleotide-disulphide oxidoreductase
DKK66_10780	COG0477	Major facilitator Superfamily
DKK66_10790	COG2113	Glycine betaine
DKK66_10805	COG1902	pentaerythritol trinitrate reductase activity
DKK66_10805	COG0446	pyridine nucleotide-disulphide oxidoreductase
DKK66_10810	COG0247	lactate metabolic process
DKK66_10810	COG2181	nitrate reductase activity
DKK66_10815	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
DKK66_10830	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DKK66_10835	COG4175	Glycine betaine
DKK66_10885	COG3383	formate dehydrogenase (NAD+) activity
DKK66_10920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DKK66_10925	COG0251	oxidation-reduction process
DKK66_10930	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
DKK66_10935	COG2610	gluconate transmembrane transporter activity
DKK66_10945	COG0572	uridine kinase
DKK66_10950	COG0625	glutathione transferase activity
DKK66_10960	COG0633	Ferredoxin
DKK66_10965	COG0443	Heat shock 70 kDa protein
DKK66_10970	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
DKK66_10980	COG0822	iron-sulfur transferase activity
DKK66_10985	COG1104	cysteine desulfurase activity
DKK66_11000	COG0747	negative chemotaxis
DKK66_11005	COG0601	transmembrane transport
DKK66_11010	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DKK66_11015	COG0444	Belongs to the ABC transporter superfamily
DKK66_11020	COG4608	Belongs to the ABC transporter superfamily
DKK66_11025	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
DKK66_11040	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DKK66_11070	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DKK66_11075	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DKK66_11080	COG0174	glutamine synthetase
DKK66_11085	COG0494	nUDIX hydrolase
DKK66_11090	COG0187	DNA topoisomerase II activity
DKK66_11095	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DKK66_11100	COG0564	pseudouridine synthase activity
DKK66_11105	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DKK66_11105	COG2904	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
DKK66_11110	COG0728	peptidoglycan biosynthetic process
DKK66_11115	COG0268	Binds directly to 16S ribosomal RNA
DKK66_11130	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
DKK66_11145	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
DKK66_11150	COG0450	alkyl hydroperoxide reductase
DKK66_11155	COG3706	GGDEF domain
DKK66_11160	COG3706	GGDEF domain
DKK66_11170	COG4181	ATPase activity
DKK66_11175	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
DKK66_11185	COG2807	transmembrane transport
DKK66_11190	COG2186	Transcriptional regulator
DKK66_11200	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
DKK66_11205	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
DKK66_11210	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
DKK66_11215	COG0470	DNA polymerase III
DKK66_11225	COG0084	hydrolase, TatD family'
DKK66_11230	COG0321	lipoyl(octanoyl) transferase activity
DKK66_11230	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
DKK66_11245	COG0156	8-amino-7-oxononanoate synthase activity
DKK66_11280	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DKK66_11285	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
DKK66_11295	COG1216	Glycosyl transferase, family 2
DKK66_11335	COG0300	oxidoreductase activity
DKK66_11340	COG1368	sulfuric ester hydrolase activity
DKK66_11350	COG3045	CreA protein
DKK66_11365	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
DKK66_11375	COG1538	Outer membrane efflux protein
DKK66_11380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKK66_11390	COG2931	calcium- and calmodulin-responsive adenylate cyclase activity
DKK66_11405	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DKK66_11425	COG0288	reversible hydration of carbon dioxide
DKK66_11430	COG1454	alcohol dehydrogenase
DKK66_11430	COG1012	belongs to the aldehyde dehydrogenase family
DKK66_11445	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
DKK66_11455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DKK66_11460	COG2132	Multicopper oxidase
DKK66_11465	COG1937	Protein conserved in bacteria
DKK66_11475	COG0360	Binds together with S18 to 16S ribosomal RNA
DKK66_11485	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
DKK66_11490	COG0359	binds to the 23S rRNA
DKK66_11500	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DKK66_11520	COG1335	isochorismatase
DKK66_11525	COG0247	lactate metabolic process
DKK66_11525	COG0277	FAD linked oxidase domain protein
DKK66_11530	COG0456	acetyltransferase
DKK66_11535	COG0456	acetyltransferase
DKK66_11550	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
DKK66_11555	COG1716	ATPase activity
DKK66_11555	COG5001	Diguanylate cyclase
DKK66_11560	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
DKK66_11570	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
DKK66_11570	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DKK66_11580	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
DKK66_11585	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
DKK66_11590	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
DKK66_11595	COG0560	Phosphoserine phosphatase
DKK66_11605	COG0697	spore germination
DKK66_11610	COG0494	nUDIX hydrolase
DKK66_11620	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
DKK66_11625	COG3161	chorismate lyase activity
DKK66_11635	COG1346	cytolysis
DKK66_11645	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
DKK66_11650	COG0583	DNA-binding transcription factor activity
DKK66_11660	COG3852	Histidine kinase
DKK66_11685	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DKK66_11690	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DKK66_11695	COG2239	Acts as a magnesium transporter
DKK66_11710	COG1047	Peptidyl-prolyl cis-trans
DKK66_11715	COG2850	peptidyl-arginine hydroxylation
DKK66_11725	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
DKK66_11730	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DKK66_11735	COG0488	(ABC) transporter
DKK66_11740	COG1028	Short-chain dehydrogenase reductase Sdr
DKK66_11745	COG0583	DNA-binding transcription factor activity
DKK66_11750	COG0175	sulfate reduction
DKK66_11770	COG0196	riboflavin kinase activity
DKK66_11775	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
DKK66_11780	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
DKK66_11785	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
DKK66_11795	COG3960	tartronate-semialdehyde synthase activity
DKK66_11800	COG3622	Belongs to the hyi family
DKK66_11805	COG2084	Dehydrogenase
DKK66_11825	COG3195	allantoin biosynthetic process
DKK66_11825	COG3648	Uricase
DKK66_11835	COG4266	Belongs to the allantoicase family
DKK66_11840	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
DKK66_11845	COG2233	PERMEase
DKK66_11855	COG0326	Molecular chaperone. Has ATPase activity
DKK66_11870	COG0583	DNA-binding transcription factor activity
DKK66_11875	COG1742	UPF0060 membrane protein
DKK66_11880	COG0625	glutathione transferase activity
DKK66_11905	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
DKK66_11910	COG0583	DNA-binding transcription factor activity
DKK66_11915	COG0531	amino acid
DKK66_11925	COG2224	Isocitrate lyase
DKK66_11930	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
DKK66_11935	COG0443	Heat shock 70 kDa protein
DKK66_11940	COG0484	heat shock protein binding
DKK66_11960	COG0583	DNA-binding transcription factor activity
DKK66_11980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
DKK66_11990	COG1063	alcohol dehydrogenase
DKK66_12000	COG0752	glycyl-tRNA synthetase alpha subunit
DKK66_12015	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
DKK66_12040	COG0400	carboxylic ester hydrolase activity
DKK66_12045	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
DKK66_12060	COG0560	Phosphoserine phosphatase
DKK66_12075	COG3220	belongs to the UPF0276 family
DKK66_12090	COG0602	queuosine metabolic process
DKK66_12095	COG0720	synthase
DKK66_12100	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
DKK66_12105	COG1597	lipid kinase activity
DKK66_12115	COG1902	pentaerythritol trinitrate reductase activity
DKK66_12120	COG0778	Nitroreductase
DKK66_12125	COG1309	transcriptional regulator
DKK66_12155	COG4969	Belongs to the N-Me-Phe pilin family
DKK66_12160	COG1454	alcohol dehydrogenase
DKK66_12165	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
DKK66_12175	COG2885	chlorophyll binding
DKK66_12185	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DKK66_12200	COG5002	protein histidine kinase activity
DKK66_12200	COG0784	Response regulator, receiver
DKK66_12200	COG2205	protein histidine kinase activity
DKK66_12210	COG0864	Transcriptional regulator
DKK66_12215	COG1122	ATPase activity
DKK66_12220	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DKK66_12225	COG0310	cobalt ion transport
DKK66_12240	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DKK66_12250	COG0318	PFAM AMP-dependent synthetase and ligase
DKK66_12280	COG0726	polysaccharide deacetylase
DKK66_12285	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DKK66_12300	COG1028	Short-chain dehydrogenase reductase Sdr
DKK66_12305	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DKK66_12310	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DKK66_12315	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DKK66_12330	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DKK66_12330	COG4797	methyltransferase
DKK66_12335	COG0778	Nitroreductase
DKK66_12345	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
DKK66_12365	COG0004	ammonium transporteR
DKK66_12370	COG1252	NADH dehydrogenase
DKK66_12375	COG0583	DNA-binding transcription factor activity
DKK66_12400	COG1335	isochorismatase
DKK66_12415	COG5001	Diguanylate cyclase
DKK66_12415	COG3706	GGDEF domain
DKK66_12415	COG4251	negative regulation of phosphorylation
DKK66_12415	COG2203	Gaf domain
DKK66_12435	COG1671	Belongs to the UPF0178 family
DKK66_12455	COG0590	tRNA wobble adenosine to inosine editing
DKK66_12480	COG0463	Glycosyl transferase, family 2
DKK66_12490	COG0519	Catalyzes the synthesis of GMP from XMP
DKK66_12490	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DKK66_12500	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
DKK66_12505	COG2867	negative regulation of translational initiation
DKK66_12510	COG2914	Belongs to the UPF0125 (RnfH) family
DKK66_12515	COG3706	GGDEF domain
DKK66_12520	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
DKK66_12525	COG0148	phosphopyruvate hydratase activity
DKK66_12530	COG2877	3-deoxy-8-phosphooctulonate synthase activity
DKK66_12535	COG0504	CTP synthase activity
DKK66_12540	COG0227	Belongs to the bacterial ribosomal protein bL28 family
DKK66_12545	COG0267	Belongs to the bacterial ribosomal protein bL33 family
DKK66_12550	COG0519	Catalyzes the synthesis of GMP from XMP
DKK66_12550	COG0518	GMP synthase (glutamine-hydrolyzing) activity
DKK66_12555	COG1573	uracil-dna glycosylase
DKK66_12560	COG0456	acetyltransferase
DKK66_12565	COG1214	PFAM Peptidase M22, glycoprotease
DKK66_12570	COG3434	signal transduction protein containing EAL and modified HD-GYP domains
DKK66_12575	COG2198	Histidine kinase
DKK66_12575	COG0643	Histidine kinase
DKK66_12580	COG3143	Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P)
DKK66_12585	COG0745	RESPONSE REGULATOR receiver
DKK66_12590	COG0784	Response regulator, receiver
DKK66_12590	COG0835	chemotaxis
DKK66_12595	COG0784	Response regulator, receiver
DKK66_12595	COG0835	chemotaxis
DKK66_12600	COG3852	Histidine kinase
DKK66_12610	COG0840	transmembrane signaling receptor activity
DKK66_12615	COG0745	RESPONSE REGULATOR receiver
DKK66_12620	COG0643	Histidine kinase
DKK66_12620	COG2198	Histidine kinase
DKK66_12630	COG0840	transmembrane signaling receptor activity
DKK66_12635	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
DKK66_12640	COG2201	protein-glutamate methylesterase activity
DKK66_12645	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
DKK66_12655	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DKK66_12660	COG0531	amino acid
DKK66_12665	COG2235	arginine
DKK66_12670	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DKK66_12680	COG0404	The glycine cleavage system catalyzes the degradation of glycine
DKK66_12685	COG0509	glycine decarboxylation via glycine cleavage system
DKK66_12695	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DKK66_12695	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
DKK66_12705	COG0747	negative chemotaxis
DKK66_12730	COG1704	LemA family
DKK66_12740	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
DKK66_12750	COG0424	maF-like protein
DKK66_12755	COG1399	metal-binding, possibly nucleic acid-binding protein
DKK66_12760	COG0333	Belongs to the bacterial ribosomal protein bL32 family
DKK66_12765	COG0416	fatty acid biosynthetic process
DKK66_12770	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
DKK66_12775	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DKK66_12780	COG1028	Short-chain dehydrogenase reductase Sdr
DKK66_12785	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
DKK66_12790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
DKK66_12795	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
DKK66_12800	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DKK66_12805	COG2199	diguanylate cyclase activity
DKK66_12805	COG2200	EAL domain
DKK66_12820	COG1028	Short-chain dehydrogenase reductase Sdr
DKK66_12860	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DKK66_12870	COG3501	Rhs element vgr protein
DKK66_12880	COG2885	chlorophyll binding
DKK66_12880	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
DKK66_12930	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DKK66_12940	COG0023	Translation Initiation Factor
DKK66_12950	COG2211	Major facilitator Superfamily
DKK66_12955	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKK66_12955	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DKK66_12960	COG1105	Belongs to the carbohydrate kinase PfkB family
DKK66_12965	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
DKK66_12965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DKK66_12970	COG1609	Transcriptional regulator
DKK66_12975	COG0583	DNA-binding transcription factor activity
DKK66_12980	COG0477	Major facilitator Superfamily
DKK66_12985	COG3038	cytochrome b561
DKK66_12995	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
DKK66_13000	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
DKK66_13010	COG0776	regulation of translation
DKK66_13020	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
DKK66_13025	COG0284	orotidine-5'-phosphate decarboxylase activity
DKK66_13030	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DKK66_13030	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DKK66_13035	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DKK66_13050	COG1028	Short-chain dehydrogenase reductase Sdr
DKK66_13055	COG4689	acetoacetate decarboxylase
DKK66_13060	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
DKK66_13070	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
DKK66_13085	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DKK66_13100	COG0395	ABC-type sugar transport system, permease component
DKK66_13115	COG3842	ATPase activity
DKK66_13120	COG4948	Mandelate Racemase Muconate Lactonizing
DKK66_13125	COG1028	Short-chain dehydrogenase reductase Sdr
DKK66_13140	COG2814	Major facilitator Superfamily
DKK66_13200	COG1648	precorrin-2 dehydrogenase activity
DKK66_13200	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
DKK66_13205	COG2010	Cytochrome c
DKK66_13210	COG3256	nitric oxide reductase
DKK66_13215	COG1845	cytochrome c oxidase, subunit III
DKK66_13225	COG0714	Associated with various cellular activities
DKK66_13290	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DKK66_13295	COG4774	siderophore transport
DKK66_13300	COG3486	L-lysine 6-monooxygenase (NADPH) activity
DKK66_13325	COG1120	ATPase activity
DKK66_13335	COG4594	ABC-type Fe3 -citrate transport system, periplasmic component
DKK66_13340	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
DKK66_13345	COG3706	GGDEF domain
DKK66_13350	COG2197	response regulator
DKK66_13355	COG3850	Histidine kinase
DKK66_13365	COG2223	nitrite transmembrane transporter activity
DKK66_13380	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
DKK66_13385	COG1140	nitrate reductase beta subunit
DKK66_13390	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
DKK66_13395	COG2181	nitrate reductase activity
DKK66_13400	COG3706	GGDEF domain
DKK66_13405	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
DKK66_13425	COG2354	Protein conserved in bacteria
DKK66_13435	COG3186	Phenylalanine-4-hydroxylase
DKK66_13440	COG0745	RESPONSE REGULATOR receiver
DKK66_13440	COG3706	GGDEF domain
DKK66_13450	COG5002	protein histidine kinase activity
DKK66_13450	COG2205	protein histidine kinase activity
DKK66_13450	COG0784	Response regulator, receiver
DKK66_13455	COG0745	RESPONSE REGULATOR receiver
DKK66_13470	COG5001	Diguanylate cyclase
DKK66_13515	COG3842	ATPase activity
DKK66_13520	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DKK66_13530	COG1522	sequence-specific DNA binding
DKK66_13535	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DKK66_13540	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DKK66_13550	COG4566	intracellular signal transduction
DKK66_13565	COG1741	Belongs to the pirin family
DKK66_13575	COG0583	DNA-binding transcription factor activity
DKK66_13580	COG1802	Transcriptional regulator
DKK66_13605	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
DKK66_13610	COG0788	formyltetrahydrofolate deformylase activity
DKK66_13630	COG1968	undecaprenyl-diphosphatase activity
DKK66_13660	COG2308	Evidence 4 Homologs of previously reported genes of
DKK66_13700	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
DKK66_13705	COG2137	regulation of response to DNA damage stimulus
DKK66_13710	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
DKK66_13715	COG1420	regulation of RNA biosynthetic process
DKK66_13720	COG2951	lytic endotransglycosylase activity
DKK66_13725	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DKK66_13730	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
DKK66_13740	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
DKK66_13745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DKK66_13755	COG2095	MarC family integral membrane protein
DKK66_13760	COG2217	Heavy metal translocating P-type atpase
DKK66_13785	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DKK66_13790	COG1393	Belongs to the ArsC family
DKK66_13800	COG0318	PFAM AMP-dependent synthetase and ligase
DKK66_13805	COG0779	Required for maturation of 30S ribosomal subunits
DKK66_13810	COG2251	uridine kinase activity
DKK66_13810	COG0195	Participates in both transcription termination and antitermination
DKK66_13815	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
DKK66_13820	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
DKK66_13825	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
DKK66_13830	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
DKK66_13835	COG1185	polyribonucleotide nucleotidyltransferase activity
DKK66_13840	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
DKK66_13855	COG1012	belongs to the aldehyde dehydrogenase family
DKK66_13860	COG3724	N-succinylarginine dihydrolase activity
DKK66_13865	COG0559	Belongs to the binding-protein-dependent transport system permease family
DKK66_13875	COG0411	ABC transporter
DKK66_13890	COG1546	Belongs to the CinA family
DKK66_13890	COG1058	Belongs to the CinA family
DKK66_13905	COG1024	Enoyl-CoA hydratase
DKK66_13910	COG1024	Enoyl-CoA hydratase
DKK66_13915	COG1960	acyl-CoA dehydrogenase activity
DKK66_13925	COG1250	3-hydroxyacyl-CoA dehydrogenase
DKK66_13930	COG0789	Transcriptional regulator
DKK66_13935	COG0183	Belongs to the thiolase family
DKK66_13940	COG0628	permease
DKK66_13965	COG3174	membrane
DKK66_13970	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
DKK66_13975	COG0142	geranyltranstransferase activity
DKK66_13980	COG1722	exodeoxyribonuclease VII activity
DKK66_13985	COG0300	oxidoreductase activity
DKK66_14010	COG1943	Transposase
DKK66_14020	COG0525	valine-tRNA ligase activity
DKK66_14025	COG3706	GGDEF domain
DKK66_14025	COG0745	RESPONSE REGULATOR receiver
DKK66_14040	COG0583	DNA-binding transcription factor activity
DKK66_14060	COG0625	glutathione transferase activity
DKK66_14070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DKK66_14080	COG3706	GGDEF domain
DKK66_14085	COG0756	dUTP diphosphatase activity
DKK66_14090	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
DKK66_14095	COG2003	Belongs to the UPF0758 family
DKK66_14120	COG0121	glutamine amidotransferase
DKK66_14125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DKK66_14135	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
DKK66_14145	COG1522	sequence-specific DNA binding
DKK66_14150	COG2070	2-Nitropropane dioxygenase
DKK66_14155	COG1335	isochorismatase
DKK66_14170	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
DKK66_14175	COG0833	amino acid
DKK66_14195	COG1454	alcohol dehydrogenase
DKK66_14200	COG0583	DNA-binding transcription factor activity
DKK66_14225	COG2995	paraquat-inducible protein a
DKK66_14230	COG3008	intermembrane lipid transfer
DKK66_14240	COG0697	spore germination
DKK66_14245	COG1187	pseudouridine synthase activity
DKK66_14275	COG0183	Belongs to the thiolase family
DKK66_14280	COG3243	poly(R)-hydroxyalkanoic acid synthase
DKK66_14285	COG0179	Fumarylacetoacetate (FAA) hydrolase
DKK66_14290	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
DKK66_14295	COG2814	Major facilitator Superfamily
DKK66_14305	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
DKK66_14315	COG0066	3-isopropylmalate dehydratase activity
DKK66_14320	COG2226	methyltransferase
DKK66_14325	COG0473	3-isopropylmalate dehydrogenase activity
DKK66_14350	COG0101	tRNA pseudouridine synthase activity
DKK66_14360	COG0133	tryptophan synthase activity
DKK66_14365	COG0159	tryptophan synthase activity
DKK66_14370	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
DKK66_14375	COG0277	FAD linked oxidase domain protein
DKK66_14380	COG0488	(ABC) transporter
DKK66_14385	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
DKK66_14390	COG1765	OsmC-like protein
DKK66_14395	COG1815	bacterial-type flagellum-dependent cell motility
DKK66_14400	COG1558	bacterial-type flagellum-dependent cell motility
DKK66_14405	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
DKK66_14410	COG1749	Flagellar hook protein flgE
DKK66_14415	COG4787	bacterial-type flagellum-dependent cell motility
DKK66_14420	COG4786	Flagellar basal body rod
DKK66_14425	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
DKK66_14430	COG1706	bacterial-type flagellum-dependent cell motility
DKK66_14435	COG1705	Flagellar rod assembly protein muramidase FlgJ
DKK66_14435	COG3951	Flagellar rod assembly protein muramidase FlgJ
DKK66_14440	COG1256	bacterial-type flagellum assembly
DKK66_14450	COG2988	succinylglutamate desuccinylase activity
DKK66_14455	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
DKK66_14465	COG2200	EAL domain
DKK66_14470	COG3842	ATPase activity
DKK66_14475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DKK66_14480	COG1166	arginine decarboxylase activity
DKK66_14485	COG0531	amino acid
DKK66_14500	COG0482	sulfurtransferase activity
DKK66_14535	COG1914	H( )-stimulated, divalent metal cation uptake system
DKK66_14545	COG0251	oxidation-reduction process
DKK66_14550	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
DKK66_14555	COG2925	Exonuclease
DKK66_14560	COG1435	thymidine kinase activity
DKK66_14570	COG0586	Pfam SNARE associated Golgi protein
DKK66_14575	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DKK66_14580	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
DKK66_14585	COG1862	Preprotein translocase
DKK66_14590	COG0343	queuine tRNA-ribosyltransferase activity
DKK66_14600	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
DKK66_14605	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DKK66_14610	COG0291	Belongs to the bacterial ribosomal protein bL35 family
DKK66_14615	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
DKK66_14620	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
DKK66_14625	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
DKK66_14625	COG0072	phenylalanine-tRNA ligase activity
DKK66_14630	COG0776	regulation of translation
DKK66_14660	COG2205	protein histidine kinase activity
DKK66_14660	COG2198	Histidine kinase
DKK66_14660	COG0784	Response regulator, receiver
DKK66_14665	COG1012	belongs to the aldehyde dehydrogenase family
DKK66_14695	COG1970	mechanosensitive ion channel activity
DKK66_14730	COG2866	Carboxypeptidase
DKK66_14760	COG4977	sequence-specific DNA binding
DKK66_14760	COG1917	Cupin 2, conserved barrel domain protein
DKK66_14765	COG1764	response to oxidative stress
DKK66_14775	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
DKK66_14780	COG4191	Histidine kinase
DKK66_14785	COG2318	DinB family
DKK66_14805	COG2204	response regulator
DKK66_14825	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
DKK66_14845	COG1773	rubredoxin
DKK66_14855	COG1773	rubredoxin
DKK66_14860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
DKK66_14910	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
DKK66_14915	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
DKK66_14935	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DKK66_14940	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DKK66_14950	COG2350	Protein conserved in bacteria
DKK66_14955	COG2917	probably involved in intracellular septation
DKK66_14970	COG1739	Uncharacterized protein family UPF0029
DKK66_14980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DKK66_14990	COG0516	GMP reductase activity
DKK66_14995	COG0840	transmembrane signaling receptor activity
DKK66_15005	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DKK66_15020	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
DKK66_15035	COG2096	Adenosyltransferase
DKK66_15045	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
DKK66_15050	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
DKK66_15060	COG0492	ferredoxin-NADP+ reductase activity
DKK66_15080	COG1309	transcriptional regulator
DKK66_15085	COG0859	PFAM glycosyl transferase family 9
DKK66_15100	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
DKK66_15110	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DKK66_15115	COG0312	modulator of DNA gyrase
DKK66_15135	COG0745	RESPONSE REGULATOR receiver
DKK66_15160	COG3706	GGDEF domain
DKK66_15160	COG0745	RESPONSE REGULATOR receiver
DKK66_15165	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DKK66_15200	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
DKK66_15225	COG1278	Cold shock
DKK66_15240	COG0412	Dienelactone hydrolase
DKK66_15255	COG3123	guanosine phosphorylase activity
DKK66_15260	COG2200	EAL domain
DKK66_15260	COG2771	luxR family
DKK66_15265	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
DKK66_15280	COG1289	transmembrane transporter activity
DKK66_15300	COG3706	GGDEF domain
DKK66_15315	COG0511	ligase activity, forming carbon-carbon bonds
DKK66_15325	COG3501	Rhs element vgr protein
DKK66_15340	COG0583	DNA-binding transcription factor activity
DKK66_15345	COG0778	Nitroreductase
DKK66_15350	COG1797	cobyrinic acid a,c-diamide synthase activity
DKK66_15380	COG2875	Belongs to the precorrin methyltransferase family
DKK66_15390	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
DKK66_15420	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
DKK66_15430	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
DKK66_15435	COG1492	cobalamin metabolic process
DKK66_15440	COG3437	response regulator, receiver
DKK66_15440	COG3850	Histidine kinase
DKK66_15440	COG2205	protein histidine kinase activity
DKK66_15440	COG4999	Histidine kinase
DKK66_15450	COG2072	flavoprotein involved in K transport
DKK66_15470	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DKK66_15475	COG0436	Aminotransferase
DKK66_15480	COG0583	DNA-binding transcription factor activity
DKK66_15490	COG2814	Major facilitator Superfamily
DKK66_15530	COG0583	DNA-binding transcription factor activity
DKK66_15535	COG2814	Major facilitator Superfamily
DKK66_15540	COG1760	l-serine dehydratase
DKK66_15555	COG2040	homocysteine
DKK66_15560	COG0840	transmembrane signaling receptor activity
DKK66_15565	COG4521	taurine ABC transporter
DKK66_15570	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
DKK66_15575	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DKK66_15580	COG2175	clavaminate synthase activity
DKK66_15585	COG0513	Belongs to the DEAD box helicase family
DKK66_15590	COG0840	transmembrane signaling receptor activity
DKK66_15595	COG2081	HI0933 family
DKK66_15605	COG0583	DNA-binding transcription factor activity
DKK66_15610	COG0019	diaminopimelate decarboxylase activity
DKK66_15615	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKK66_15630	COG0688	phosphatidylethanolamine metabolic process
DKK66_15635	COG3706	GGDEF domain
DKK66_15675	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
DKK66_15685	COG0481	GTPase activity
DKK66_15690	COG0681	Belongs to the peptidase S26 family
DKK66_15700	COG0571	ribonuclease III activity
DKK66_15705	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
DKK66_15715	COG1381	Involved in DNA repair and RecF pathway recombination
DKK66_15720	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
DKK66_15725	COG1988	membrane-bound metal-dependent
DKK66_15730	COG0736	holo-[acyl-carrier-protein] synthase activity
DKK66_15735	COG1472	Belongs to the glycosyl hydrolase 3 family
DKK66_15750	COG1643	Atp-dependent helicase
DKK66_15780	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
DKK66_15825	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
DKK66_15860	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
DKK66_15875	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
DKK66_15885	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DKK66_15945	COG1619	proteins homologs of microcin C7 resistance protein MccF
DKK66_15955	COG0175	sulfate reduction
DKK66_15960	COG2895	sulfate adenylyltransferase (ATP) activity
DKK66_15970	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
DKK66_15975	COG0564	pseudouridine synthase activity
DKK66_16045	COG1294	oxidase, subunit
DKK66_16065	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
DKK66_16070	COG0583	DNA-binding transcription factor activity
DKK66_16075	COG4221	oxidoreductase activity
DKK66_16085	COG0667	Aldo Keto reductase
DKK66_16100	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKK66_16110	COG1538	Outer membrane efflux protein
DKK66_16125	COG1621	beta-fructofuranosidase activity
DKK66_16135	COG1609	Transcriptional regulator
DKK66_16140	COG0583	DNA-binding transcription factor activity
DKK66_16150	COG1028	Short-chain dehydrogenase reductase Sdr
DKK66_16155	COG0583	DNA-binding transcription factor activity
DKK66_16175	COG3243	poly(R)-hydroxyalkanoic acid synthase
DKK66_16180	COG2431	L-lysine efflux transmembrane transporter activity
DKK66_16190	COG2814	Major facilitator Superfamily
DKK66_16195	COG0583	DNA-binding transcription factor activity
DKK66_16205	COG0625	glutathione transferase activity
DKK66_16210	COG2378	regulation of single-species biofilm formation
DKK66_16215	COG0583	DNA-binding transcription factor activity
DKK66_16240	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DKK66_16265	COG0497	DNA recombination
DKK66_16270	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
DKK66_16285	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
DKK66_16290	COG0123	including yeast histone deacetylase and acetoin utilization protein
DKK66_16320	COG1012	belongs to the aldehyde dehydrogenase family
DKK66_16330	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
DKK66_16350	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DKK66_16355	COG0583	DNA-binding transcription factor activity
DKK66_16365	COG2119	membrane
DKK66_16375	COG1345	Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end
DKK66_16380	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
DKK66_16400	COG2824	Alkylphosphonate utilization operon protein PhnA
DKK66_16405	COG0534	Mate efflux family protein
DKK66_16435	COG0415	Belongs to the DNA photolyase family
DKK66_16440	COG3380	Catalyzes the oxidation of the 1,2-dihydro- and 1,6- dihydro- isomeric forms of beta-NAD(P) back to beta-NAD(P) . May serve to protect primary metabolism dehydrogenases from inhibition by the 1,2-dihydro- and 1,6-dihydro-beta-NAD(P) isomers
DKK66_16455	COG3046	protein related to deoxyribodipyrimidine photolyase
DKK66_16460	COG0415	Belongs to the DNA photolyase family
DKK66_16475	COG4221	oxidoreductase activity
DKK66_16485	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DKK66_16495	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
DKK66_16500	COG1309	transcriptional regulator
DKK66_16505	COG0765	amino acid transport
DKK66_16510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DKK66_16555	COG0583	DNA-binding transcription factor activity
DKK66_16570	COG0583	DNA-binding transcription factor activity
DKK66_16575	COG2200	EAL domain
DKK66_16575	COG3287	FIST C domain
DKK66_16575	COG2199	diguanylate cyclase activity
DKK66_16580	COG0009	L-threonylcarbamoyladenylate synthase
DKK66_16585	COG3002	Belongs to the UPF0753 family
DKK66_16590	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
DKK66_16595	COG0583	DNA-binding transcription factor activity
DKK66_16605	COG3284	Transcriptional regulator
DKK66_16610	COG0145	ligase activity
DKK66_16615	COG0146	N-methylhydantoinase B acetone carboxylase alpha subunit
DKK66_16620	COG4647	ligase activity
DKK66_16625	COG3707	response regulator
DKK66_16630	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DKK66_16630	COG1116	anion transmembrane transporter activity
DKK66_16635	COG2223	nitrite transmembrane transporter activity
DKK66_16640	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
DKK66_16650	COG0243	molybdopterin cofactor binding
DKK66_16670	COG0583	DNA-binding transcription factor activity
DKK66_16680	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DKK66_16690	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DKK66_16790	COG4983	Phage plasmid primase, P4 family domain protein
DKK66_16845	COG0582	viral genome integration into host DNA
DKK66_16870	COG3550	peptidyl-serine autophosphorylation
DKK66_16910	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DKK66_16925	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DKK66_16925	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DKK66_16950	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DKK66_16950	COG0047	phosphoribosylformylglycinamidine synthase activity
DKK66_16970	COG1741	Belongs to the pirin family
DKK66_16980	COG1028	Short-chain dehydrogenase reductase Sdr
DKK66_16985	COG1335	isochorismatase
DKK66_16990	COG1335	isochorismatase
DKK66_17015	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DKK66_17030	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DKK66_17070	COG0346	lactoylglutathione lyase activity
DKK66_17085	COG2217	Heavy metal translocating P-type atpase
DKK66_17105	COG0747	negative chemotaxis
DKK66_17115	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
DKK66_17120	COG1538	Outer membrane efflux protein
DKK66_17125	COG1309	transcriptional regulator
DKK66_17135	COG0667	Aldo Keto reductase
DKK66_17150	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DKK66_17160	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
DKK66_17170	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
DKK66_17175	COG1674	ftsk spoiiie
DKK66_17180	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
DKK66_17195	COG1024	Enoyl-CoA hydratase
DKK66_17210	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DKK66_17225	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
DKK66_17255	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DKK66_17300	COG1215	transferase activity, transferring glycosyl groups
DKK66_17305	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
DKK66_17315	COG0840	transmembrane signaling receptor activity
DKK66_17320	COG0436	Aminotransferase
DKK66_17325	COG1522	sequence-specific DNA binding
DKK66_17335	COG2390	Transcriptional regulator
DKK66_17350	COG1175	transmembrane transport
DKK66_17365	COG3842	ATPase activity
DKK66_17370	COG0246	Mannitol dehydrogenase
DKK66_17375	COG1070	Carbohydrate kinase
DKK66_17380	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DKK66_17390	COG0725	ABC transporter, periplasmic molybdate-binding protein
DKK66_17395	COG4149	molybdate abc transporter
DKK66_17400	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
DKK66_17415	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DKK66_17420	COG0513	Belongs to the DEAD box helicase family
DKK66_17430	COG3437	response regulator, receiver
DKK66_17435	COG0840	transmembrane signaling receptor activity
DKK66_17445	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DKK66_17480	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
DKK66_17500	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
DKK66_17505	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
DKK66_17510	COG0174	glutamine synthetase
DKK66_17525	COG1538	Outer membrane efflux protein
DKK66_17530	COG1566	PFAM secretion protein HlyD family protein
DKK66_17535	COG2814	Major facilitator Superfamily
DKK66_17540	COG1538	Outer membrane efflux protein
DKK66_17545	COG0577	efflux transmembrane transporter activity
DKK66_17545	COG1136	(ABC) transporter
DKK66_17550	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKK66_17560	COG2197	response regulator
DKK66_17565	COG0820	rRNA (adenine-C2-)-methyltransferase activity
DKK66_17590	COG0419	ATPase involved in DNA repair
DKK66_17595	COG0420	3'-5' exonuclease activity
DKK66_17605	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
DKK66_17615	COG1278	Cold shock
DKK66_17640	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
DKK66_17645	COG0321	lipoyl(octanoyl) transferase activity
DKK66_17650	COG2921	Belongs to the UPF0250 family
DKK66_17655	COG1686	Belongs to the peptidase S11 family
DKK66_17660	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DKK66_17710	COG3052	prosthetic group binding
DKK66_17730	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DKK66_17745	COG1028	Short-chain dehydrogenase reductase Sdr
DKK66_17750	COG1802	Transcriptional regulator
DKK66_17760	COG0679	Auxin Efflux Carrier
DKK66_17770	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DKK66_17780	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DKK66_17800	COG0577	efflux transmembrane transporter activity
DKK66_17800	COG1136	(ABC) transporter
DKK66_17815	COG0004	ammonium transporteR
DKK66_17845	COG4191	Histidine kinase
DKK66_17945	COG2205	protein histidine kinase activity
DKK66_17945	COG2198	Histidine kinase
DKK66_17945	COG0784	Response regulator, receiver
DKK66_17955	COG2831	hemolysin activation secretion protein
DKK66_17960	COG2197	response regulator
DKK66_17970	COG3842	ATPase activity
DKK66_17980	COG1176	ABC-type spermidine putrescine transport system, permease component I
DKK66_17985	COG1177	transmembrane transport
DKK66_17995	COG3706	GGDEF domain
DKK66_18010	COG1763	Mo-molybdopterin cofactor biosynthetic process
DKK66_18030	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DKK66_18035	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DKK66_18040	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DKK66_18045	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
DKK66_18050	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
DKK66_18070	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
DKK66_18080	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
DKK66_18085	COG0233	cytoplasmic translational termination
DKK66_18090	COG0528	UMP kinase activity
DKK66_18095	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
DKK66_18100	COG0052	Belongs to the universal ribosomal protein uS2 family
DKK66_18115	COG0477	Major facilitator Superfamily
DKK66_18125	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
DKK66_18130	COG2816	NAD+ diphosphatase activity
DKK66_18140	COG0166	Belongs to the GPI family
DKK66_18145	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
DKK66_18150	COG0501	Belongs to the peptidase M48B family
DKK66_18155	COG2154	pterin-4-alpha-carbinolamine dehydratase
DKK66_18165	COG1028	Short-chain dehydrogenase reductase Sdr
DKK66_18170	COG1956	GAF domain-containing protein
DKK66_18190	COG4974	Belongs to the 'phage' integrase family
DKK66_18195	COG0443	Heat shock 70 kDa protein
DKK66_18205	COG2321	neutral zinc metallopeptidase
DKK66_18210	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
DKK66_18220	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
DKK66_18225	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
DKK66_18235	COG0307	riboflavin synthase, alpha
DKK66_18240	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
DKK66_18255	COG0842	Transport permease protein
DKK66_18260	COG1129	ABC transporter
DKK66_18260	COG0842	Transport permease protein
DKK66_18265	COG1131	(ABC) transporter
DKK66_18270	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
DKK66_18300	COG5001	Diguanylate cyclase
DKK66_18300	COG5002	protein histidine kinase activity
DKK66_18300	COG3447	MASE1 domain protein
DKK66_18315	COG0583	DNA-binding transcription factor activity
DKK66_18325	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
DKK66_18330	COG0745	RESPONSE REGULATOR receiver
DKK66_18345	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DKK66_18350	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DKK66_18355	COG1045	serine acetyltransferase
DKK66_18370	COG2011	ABC-type metal ion transport system permease component
DKK66_18375	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DKK66_18385	COG1116	anion transmembrane transporter activity
DKK66_18390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DKK66_18395	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DKK66_18400	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DKK66_18405	COG0431	NADPH-dependent FMN reductase
DKK66_18415	COG1113	amino acid transport
DKK66_18420	COG4191	Histidine kinase
DKK66_18435	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DKK66_18440	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DKK66_18455	COG2822	iron ion transport
DKK66_18475	COG2199	diguanylate cyclase activity
DKK66_18475	COG2203	Gaf domain
DKK66_18480	COG2372	response to copper ion
DKK66_18485	COG1276	copper resistance
DKK66_18500	COG2249	NAD(P)H dehydrogenase (quinone) activity
DKK66_18510	COG1979	alcohol dehydrogenase
DKK66_18520	COG2207	Transcriptional regulator
DKK66_18525	COG0348	domain, Protein
DKK66_18545	COG0450	alkyl hydroperoxide reductase
DKK66_18550	COG2175	clavaminate synthase activity
DKK66_18555	COG0679	Auxin Efflux Carrier
DKK66_18565	COG0477	Major facilitator Superfamily
DKK66_18580	COG2814	Major facilitator Superfamily
DKK66_18600	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DKK66_18620	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DKK66_18630	COG1082	Xylose isomerase domain protein TIM barrel
DKK66_18635	COG0583	DNA-binding transcription factor activity
DKK66_18650	COG0667	Aldo Keto reductase
DKK66_18685	COG2159	amidohydrolase
DKK66_18690	COG2828	Protein conserved in bacteria
DKK66_18700	COG3290	protein histidine kinase activity
DKK66_18700	COG0840	transmembrane signaling receptor activity
DKK66_18705	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DKK66_18710	COG3501	Rhs element vgr protein
DKK66_18765	COG1473	amidohydrolase
DKK66_18770	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DKK66_18775	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
DKK66_18805	COG2198	Histidine kinase
DKK66_18805	COG0784	Response regulator, receiver
DKK66_18805	COG2205	protein histidine kinase activity
DKK66_18810	COG3300	MHYT domain
DKK66_18810	COG5001	Diguanylate cyclase
DKK66_18820	COG0281	malic enzyme
DKK66_18820	COG0280	phosphate acetyltransferase
DKK66_18825	COG0840	transmembrane signaling receptor activity
DKK66_18830	COG3706	GGDEF domain
DKK66_18835	COG0583	DNA-binding transcription factor activity
DKK66_18850	COG3706	GGDEF domain
DKK66_18850	COG0745	RESPONSE REGULATOR receiver
DKK66_18895	COG0488	(ABC) transporter
DKK66_18940	COG1858	cytochrome C peroxidase
DKK66_18960	COG1595	DNA-templated transcription, initiation
DKK66_18965	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
DKK66_18975	COG1294	oxidase, subunit
DKK66_18995	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
DKK66_19000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
DKK66_19005	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
DKK66_19020	COG2188	Transcriptional regulator
DKK66_19030	COG0765	amino acid transport
DKK66_19040	COG1126	abc transporter atp-binding protein
DKK66_19045	COG4266	Belongs to the allantoicase family
DKK66_19050	COG3194	Catalyzes the catabolism of the allantoin degradation intermediate (S)-ureidoglycolate, generating urea and glyoxylate. Involved in the utilization of allantoin as nitrogen source
DKK66_19060	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DKK66_19065	COG0798	PFAM Bile acid sodium symporter
DKK66_19080	COG2169	Transcriptional regulator
DKK66_19080	COG1917	Cupin 2, conserved barrel domain protein
DKK66_19115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
DKK66_19155	COG0803	Belongs to the bacterial solute-binding protein 9 family
DKK66_19165	COG0523	cobalamin synthesis protein
DKK66_19190	COG1960	acyl-CoA dehydrogenase activity
DKK66_19220	COG0270	DNA (cytosine-5-)-methyltransferase activity
DKK66_19255	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
DKK66_19255	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DKK66_19265	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
DKK66_19275	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
DKK66_19280	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
DKK66_19285	COG3023	N-Acetylmuramoyl-L-alanine amidase
DKK66_19290	COG1024	Enoyl-CoA hydratase
DKK66_19300	COG0803	Belongs to the bacterial solute-binding protein 9 family
DKK66_19305	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DKK66_19310	COG1121	(ABC) transporter
DKK66_19315	COG0523	cobalamin synthesis protein
DKK66_19320	COG0735	belongs to the Fur family
DKK66_19340	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
DKK66_19350	COG3622	Belongs to the hyi family
DKK66_19355	COG0513	Belongs to the DEAD box helicase family
DKK66_19360	COG0006	proline dipeptidase activity
DKK66_19365	COG0018	arginyl-trna synthetase
DKK66_19375	COG1177	transmembrane transport
DKK66_19380	COG1176	ABC-type spermidine putrescine transport system, permease component I
DKK66_19405	COG2833	Protein of unknown function (DUF455)
DKK66_19410	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
DKK66_19415	COG2818	Glycosylase
DKK66_19425	COG0733	neurotransmitter:sodium symporter activity
DKK66_19430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DKK66_19460	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DKK66_19465	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DKK66_19470	COG2195	Cleaves the N-terminal amino acid of tripeptides
DKK66_19480	COG5002	protein histidine kinase activity
DKK66_19480	COG5001	Diguanylate cyclase
DKK66_19485	COG5265	(ABC) transporter
DKK66_19490	COG2967	ApaG domain
DKK66_19495	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DKK66_19500	COG1028	Short-chain dehydrogenase reductase Sdr
DKK66_19505	COG0546	phosphoglycolate phosphatase activity
DKK66_19525	COG1196	nuclear chromosome segregation
DKK66_19525	COG0739	heme binding
DKK66_19525	COG0741	lytic transglycosylase activity
DKK66_19535	COG0617	tRNA 3'-terminal CCA addition
DKK66_19550	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DKK66_19565	COG1360	Flagellar Motor Protein
DKK66_19580	COG0174	glutamine synthetase
DKK66_19585	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DKK66_19590	COG1917	Cupin 2, conserved barrel domain protein
DKK66_19590	COG1396	sequence-specific DNA binding
DKK66_19595	COG1012	belongs to the aldehyde dehydrogenase family
DKK66_19600	COG0840	transmembrane signaling receptor activity
DKK66_19605	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
DKK66_19610	COG1666	GTP binding
DKK66_19615	COG1280	lysine exporter protein (LysE YggA)
DKK66_19625	COG0137	argininosuccinate synthase activity
DKK66_19630	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
DKK66_19640	COG1199	ATP-dependent helicase activity
DKK66_19655	COG0024	Methionine aminopeptidase
DKK66_19660	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
DKK66_19665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DKK66_19675	COG3411	Ferredoxin
DKK66_19680	COG0305	Participates in initiation and elongation during chromosome replication
DKK66_19685	COG2081	HI0933 family
DKK66_19690	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
DKK66_19695	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
DKK66_19715	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
DKK66_19720	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
DKK66_19725	COG0740	serine-type endopeptidase activity
DKK66_19730	COG0544	peptidyl-prolyl cis-trans isomerase activity
DKK66_19780	COG3831	ATPase activity
DKK66_19785	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
DKK66_20010	COG0305	Participates in initiation and elongation during chromosome replication