locus-tag	class	description
E0W69_000010	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
E0W69_000015	ENOG4105DFU	Cell wall formation (By similarity)
E0W69_000025	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
E0W69_000030	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
E0W69_000035	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
E0W69_000040	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
E0W69_000045	ENOG4107VNI	ribosomal protein l10
E0W69_000050	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
E0W69_000065	ENOG4105DKQ	ROK family
E0W69_000075	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_000100	ENOG4107TUY	Histidine kinase
E0W69_000105	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_000135	ENOG4105CWX	Alpha-1,2-mannosidase
E0W69_000150	ENOG4105CWX	Alpha-1,2-mannosidase
E0W69_000155	ENOG4105CWX	Alpha-1,2-mannosidase
E0W69_000165	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E0W69_000170	ENOG4108NEV	two component transcriptional regulator, LytTR family
E0W69_000215	ENOG4105CD8	aminopeptidase N
E0W69_000230	ENOG4105F0N	pyrophosphate phospho-hydrolase
E0W69_000235	ENOG4107R4J	Chloride channel
E0W69_000245	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
E0W69_000270	ENOG4105CYC	Transferase
E0W69_000280	ENOG4105K70	DNA-binding protein
E0W69_000290	ENOG4105C03	ribonuclease
E0W69_000315	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
E0W69_000330	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
E0W69_000335	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
E0W69_000340	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E0W69_000355	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
E0W69_000370	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
E0W69_000390	ENOG4105CHR	reductase
E0W69_000400	ENOG4105E1F	short-chain dehydrogenase reductase
E0W69_000405	ENOG4108IND	Tetr family transcriptional regulator
E0W69_000415	ENOG4105BZ1	(ABC) transporter
E0W69_000425	ENOG4105KDC	50s ribosomal protein l28
E0W69_000430	ENOG41083ND	50S ribosomal protein L33
E0W69_000445	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
E0W69_000490	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
E0W69_000565	ENOG4107T8J	thymidine kinase
E0W69_000590	ENOG4105RKW	reductase (By
E0W69_000600	ENOG4107W2A	UPF0173 metal-dependent hydrolase
E0W69_000605	ENOG4107QJE	Chromosome Partitioning Protein
E0W69_000610	ENOG4105FA0	parb-like partition protein
E0W69_000620	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
E0W69_000625	ENOG4105CQB	FAD linked oxidase domain protein
E0W69_000650	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
E0W69_000665	ENOG4108JPV	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
E0W69_000680	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
E0W69_000705	ENOG4105EMU	Dehydrogenase
E0W69_000725	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E0W69_000735	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
E0W69_000740	ENOG4108N9J	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
E0W69_000745	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
E0W69_000765	ENOG4107Y2X	deaminase
E0W69_000800	ENOG4105CMR	udp-glucose 4-epimerase
E0W69_000805	ENOG4105CPK	Glycosyl transferase (Group 1
E0W69_000810	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
E0W69_000830	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
E0W69_000855	ENOG4105DFU	Cell wall formation (By similarity)
E0W69_000860	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
E0W69_000865	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
E0W69_000870	ENOG4105EAA	nucleoside
E0W69_000890	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
E0W69_000945	ENOG4108IYU	L-aspartate oxidase
E0W69_000960	ENOG4105US7	Histidine kinase
E0W69_000975	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_000995	ENOG4105E2D	ec 3.2.1.52
E0W69_001005	ENOG4107G87	m6 family metalloprotease domain protein
E0W69_001030	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
E0W69_001055	ENOG4108DT4	serine threonine protein kinase
E0W69_001060	ENOG4105CPF	Cell wall formation (By similarity)
E0W69_001065	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
E0W69_001090	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_001110	ENOG4105CI2	imidazolone-5-propionate hydrolase
E0W69_001120	ENOG4105C5Z	peptidase
E0W69_001125	ENOG4105EGS	Mechanosensitive ion channel
E0W69_001130	ENOG4105CDY	transcriptional regulatory protein
E0W69_001135	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
E0W69_001145	ENOG4105CKI	cobalamin synthesis protein
E0W69_001150	ENOG4107QJT	sodium dicarboxylate symporter
E0W69_001155	ENOG410645S	MarR family Transcriptional regulator
E0W69_001160	ENOG410645S	MarR family Transcriptional regulator
E0W69_001175	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E0W69_001180	ENOG4105CSG	Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps (By similarity)
E0W69_001195	ENOG4105DFH	Transport of potassium into the cell (By similarity)
E0W69_001215	ENOG4105C5Q	Transcriptional regulator
E0W69_001220	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
E0W69_001225	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
E0W69_001245	ENOG4105W5Q	DNA repair protein (RadC
E0W69_001250	ENOG4108UVJ	appr-1-p processing domain protein
E0W69_001290	ENOG4108VBH	Uncharacterized protein conserved in bacteria (DUF2251)
E0W69_001405	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_001455	ENOG4107QP3	malate synthase g
E0W69_001465	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
E0W69_001475	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
E0W69_001495	ENOG4105CFG	Acts as a chaperone (By similarity)
E0W69_001510	ENOG4105CPC	Aldo Keto reductase
E0W69_001530	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
E0W69_001535	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
E0W69_001540	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
E0W69_001555	ENOG4108IUK	alpha amylase, catalytic
E0W69_001580	ENOG4105CCN	Peptidase M56
E0W69_001590	ENOG4105D9R	oxidoreductase
E0W69_001645	ENOG4105HMI	Membrane
E0W69_001650	ENOG4105DUM	transcriptional regulator, lysR family
E0W69_001670	ENOG4105VMP	Transcriptional regulator
E0W69_001690	ENOG4105CYW	agmatinase
E0W69_001700	ENOG4105E0M	Sulfatase
E0W69_001715	ENOG41083J0	(ABC) transporter
E0W69_001720	ENOG4105C4B	ABC transporter, permease
E0W69_001730	ENOG4105C5H	ABC transporter
E0W69_001735	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
E0W69_001745	ENOG4105CMR	udp-glucose 4-epimerase
E0W69_001750	ENOG4108IUS	Transketolase
E0W69_001770	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
E0W69_001775	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
E0W69_001780	ENOG4105DQ4	alcohol dehydrogenase
E0W69_001790	ENOG4105DR4	Methyltransferase
E0W69_001805	ENOG41060VI	Involved in DNA repair and RecF pathway recombination (By similarity)
E0W69_001825	ENOG4105DF6	Fe-S oxidoreductase
E0W69_001830	ENOG4105C2X	Arabinose 5-phosphate isomerase
E0W69_001875	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
E0W69_001880	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
E0W69_001885	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
E0W69_001900	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
E0W69_001910	ENOG4105KUZ	arsenate reductase
E0W69_001920	ENOG4105C28	cystathionine
E0W69_001925	ENOG4105CAQ	asparagine synthetase
E0W69_001955	ENOG4105C37	(CBS) domain
E0W69_001960	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
E0W69_001990	ENOG4105C3M	thioredoxin reductase
E0W69_002015	ENOG4107SVC	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E0W69_002020	ENOG41067QG	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
E0W69_002025	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
E0W69_002090	ENOG4105CEV	competence damage-inducible protein
E0W69_002095	ENOG4106HRJ	d-alanyl-d-alanine carboxypeptidase
E0W69_002115	ENOG41075H3	AraC family transcriptional regulator
E0W69_002135	ENOG4105KVH	Transcriptional regulator
E0W69_002140	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
E0W69_002145	ENOG4105D44	asparaginase
E0W69_002155	ENOG4105D5Q	Arginine ornithine antiporter
E0W69_002160	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
E0W69_002165	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
E0W69_002170	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E0W69_002175	ENOG4108I0Z	Aconitate hydratase
E0W69_002200	ENOG4108UUM	single-stranded DNA-binding protein
E0W69_002210	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
E0W69_002220	ENOG4105CGK	Exodeoxyribonuclease III
E0W69_002230	ENOG4105K70	DNA-binding protein
E0W69_002260	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E0W69_002265	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
E0W69_002285	ENOG4105CFH	Aspartokinase
E0W69_002290	ENOG4107RDY	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
E0W69_002295	ENOG4105D98	threonine synthase
E0W69_002300	ENOG4108IUW	ABC transporter
E0W69_002310	ENOG4107RF4	Phosphodiesterase
E0W69_002330	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
E0W69_002340	ENOG4105CHM	Aminotransferase
E0W69_002355	ENOG4105CUB	amino acid
E0W69_002360	ENOG4105C3G	gtp-binding protein
E0W69_002365	ENOG4105E0M	Sulfatase
E0W69_002370	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
E0W69_002390	ENOG4108VHC	Short-chain dehydrogenase reductase Sdr
E0W69_002405	ENOG4105C28	cystathionine
E0W69_002410	ENOG4105CHM	Aminotransferase
E0W69_002415	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
E0W69_002455	ENOG4105K5M	30s ribosomal protein S16
E0W69_002460	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
E0W69_002470	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E0W69_002485	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E0W69_002490	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
E0W69_002500	ENOG4105W5Q	DNA repair protein (RadC
E0W69_002535	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_002600	ENOG4105W5Q	DNA repair protein (RadC
E0W69_002615	ENOG4107QRI	Phosphoketolase
E0W69_002620	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
E0W69_002650	ENOG4108HRK	Histidine kinase
E0W69_002655	ENOG4105DY9	regulatoR
E0W69_002690	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_002745	ENOG4108JJA	ABC, transporter
E0W69_002820	ENOG4108IG5	Transcriptional regulator
E0W69_002825	ENOG4108SJC	Membrane
E0W69_002870	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
E0W69_002875	ENOG4105ECQ	AraC Family Transcriptional Regulator
E0W69_002885	ENOG41077A9	carbonic anhydrase
E0W69_002890	ENOG4105CHR	reductase
E0W69_002925	ENOG41076HS	cation diffusion facilitator family transporter
E0W69_002935	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
E0W69_002940	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
E0W69_002945	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E0W69_002955	ENOG4105C9U	ATP-dependent DNA helicase RecQ
E0W69_002960	ENOG4105DVE	abc transporter atp-binding protein
E0W69_002980	ENOG4105C4R	Atp-dependent dna helicase
E0W69_003000	ENOG4105C3J	Cysteine desulfurase
E0W69_003010	ENOG4105CUG	Oligopeptidase b
E0W69_003025	ENOG4105FE9	pseudouridine synthase
E0W69_003030	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
E0W69_003035	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
E0W69_003050	ENOG4105C9A	Phoh family
E0W69_003080	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_003085	ENOG4105TT1	Ragb susd domain-containing protein
E0W69_003090	ENOG4108MYR	Secreted protein
E0W69_003100	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
E0W69_003115	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
E0W69_003135	ENOG4107RJ9	Cell division protein FtsX
E0W69_003140	ENOG4105C8T	Leucyl-tRNA synthetase
E0W69_003155	ENOG4108IG5	Transcriptional regulator
E0W69_003160	ENOG4105DR5	peptidase
E0W69_003175	ENOG4107ZT5	Thiol disulfide interchange protein
E0W69_003185	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E0W69_003200	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
E0W69_003215	ENOG41068JE	domain protein
E0W69_003220	ENOG4105ETE	Transcriptional regulator (LacI family
E0W69_003235	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
E0W69_003250	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
E0W69_003260	ENOG4105C02	permease
E0W69_003280	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
E0W69_003285	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
E0W69_003295	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E0W69_003305	ENOG4105DTQ	mandelate racemase muconate lactonizing
E0W69_003315	ENOG4105UYK	outer membrane protein a
E0W69_003320	ENOG4105CFH	Aspartokinase
E0W69_003340	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
E0W69_003350	ENOG4107R55	ethanolamine transporter
E0W69_003355	ENOG4105CPD	ethanolamine ammonia-lyase
E0W69_003360	ENOG4107FQ9	ethanolamine ammonia-lyase
E0W69_003420	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
E0W69_003425	ENOG41073TP	transcriptional regulator
E0W69_003445	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
E0W69_003460	ENOG4105EEQ	Na H antiporter
E0W69_003465	ENOG4108NEV	two component transcriptional regulator, LytTR family
E0W69_003470	ENOG4108HRK	Histidine kinase
E0W69_003490	ENOG4108HWY	Beta-lactamase
E0W69_003500	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
E0W69_003505	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
E0W69_003510	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
E0W69_003520	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
E0W69_003525	ENOG4105D64	Mechanosensitive ion channel
E0W69_003535	ENOG4105K7K	Transcriptional regulator
E0W69_003545	ENOG4108NEV	two component transcriptional regulator, LytTR family
E0W69_003565	ENOG4105J5G	Transferase hexapeptide repeat containing protein
E0W69_003575	ENOG4105EGS	Mechanosensitive ion channel
E0W69_003580	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
E0W69_003585	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E0W69_003605	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
E0W69_003615	ENOG4105D05	Receptor
E0W69_003650	ENOG4105Q95	Cupin 2, conserved barrel domain protein
E0W69_003655	ENOG4108VPT	UPF0234 protein
E0W69_003675	ENOG4108Z03	MAF-like protein
E0W69_003700	ENOG4105DTQ	mandelate racemase muconate lactonizing
E0W69_003710	ENOG4105F0Z	galactose-1-phosphate uridylyltransferase
E0W69_003715	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
E0W69_003730	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
E0W69_003735	ENOG4105CHR	reductase
E0W69_003740	ENOG4105ETE	Transcriptional regulator (LacI family
E0W69_003760	ENOG4108RAV	Conserved protein
E0W69_003765	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
E0W69_003775	ENOG4105C56	H( )-stimulated, divalent metal cation uptake system (By similarity)
E0W69_003785	ENOG4105CAT	Cytidine monophosphate kinase
E0W69_003795	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_003810	ENOG4105VJV	50s ribosomal protein L35
E0W69_003815	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
E0W69_003820	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
E0W69_003825	ENOG4105CX6	glutaminyL-tRNA synthetase
E0W69_003830	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
E0W69_003835	ENOG4105VFU	Rna-binding protein
E0W69_003840	ENOG4105VEQ	Cold shock protein
E0W69_003850	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
E0W69_003875	ENOG4108Z5K	methylglyoxal synthase
E0W69_003885	ENOG4105DZ0	fad dependent oxidoreductase
E0W69_003895	ENOG4107S1W	4-alpha-glucanotransferase
E0W69_003910	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
E0W69_003915	ENOG4107Z6X	Transcriptional regulator
E0W69_003925	ENOG4107ZT5	Thiol disulfide interchange protein
E0W69_003935	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_003945	ENOG4105VYW	UPF0251 protein
E0W69_003950	ENOG4107RAN	Peptidase, M16
E0W69_003965	ENOG4105ID8	Transcriptional regulator, ARAC family
E0W69_003970	ENOG4105CHR	reductase
E0W69_003990	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
E0W69_003995	ENOG4105F5W	AtP-binding protein
E0W69_004000	ENOG4105D70	Integrase catalytic subunit
E0W69_004015	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
E0W69_004020	ENOG4106UW1	Major Facilitator superfamily
E0W69_004025	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
E0W69_004030	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
E0W69_004040	ENOG4108MCI	Transcriptional regulator, ARAC family
E0W69_004055	ENOG4105CPC	Aldo Keto reductase
E0W69_004100	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
E0W69_004105	ENOG4108ZHJ	Organic hydroperoxide resistance protein
E0W69_004115	ENOG4108RCM	Nitroreductase
E0W69_004120	ENOG4105K56	Transcriptional regulator
E0W69_004145	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
E0W69_004165	ENOG4105C5H	ABC transporter
E0W69_004170	ENOG4107RAJ	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
E0W69_004185	ENOG4108IA2	Sodium pantothenate symporter
E0W69_004200	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
E0W69_004205	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
E0W69_004210	ENOG4105HCZ	
E0W69_004215	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
E0W69_004220	ENOG4105E7U	AraC family transcriptional regulator
E0W69_004245	ENOG4105C75	arginyL-tRNA synthetase
E0W69_004250	ENOG4105ZMH	deoxynucleoside kinase
E0W69_004255	ENOG4105C31	Tryptophanyl-tRNA synthetase
E0W69_004270	ENOG4107R1M	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) (By similarity)
E0W69_004285	ENOG4107RWD	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
E0W69_004290	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
E0W69_004295	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
E0W69_004320	ENOG4105CIN	aminoacyl-histidine dipeptidase
E0W69_004325	ENOG4105C26	Dehydrogenase
E0W69_004345	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
E0W69_004360	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
E0W69_004370	ENOG4105CUZ	uba thif-type nad fad binding protein
E0W69_004380	ENOG41062JF	Transcriptional regulator
E0W69_004390	ENOG4105D3W	isochorismatase
E0W69_004405	ENOG4105KVH	Transcriptional regulator
E0W69_004420	ENOG4108S2Y	peptide Chain Release factor
E0W69_004430	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
E0W69_004435	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
E0W69_004440	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
E0W69_004445	ENOG4108Z4K	mutator MutT protein
E0W69_004450	ENOG4105C1K	alpha-alpha-trehalose-phosphate synthase
E0W69_004455	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
E0W69_004465	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
E0W69_004470	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
E0W69_004480	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
E0W69_004505	ENOG4105H9W	Short-chain dehydrogenase reductase Sdr
E0W69_004510	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
E0W69_004530	ENOG4105CJW	magnesium transporter
E0W69_004535	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
E0W69_004545	ENOG4108Z66	YbaK ebsC protein
E0W69_004550	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
E0W69_004560	ENOG4105CRQ	synthase (Component I)
E0W69_004570	ENOG4105DDQ	anthranilate synthase
E0W69_004575	ENOG4108I0Q	anthranilate phosphoribosyltransferase
E0W69_004585	ENOG4105DK0	Indole-3-glycerol phosphate synthase
E0W69_004590	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
E0W69_004605	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
E0W69_004610	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
E0W69_004615	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
E0W69_004620	ENOG4105E15	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
E0W69_004625	ENOG4105C2N	RNA methyltransferase TrmH family group 3
E0W69_004630	ENOG4107QJT	sodium dicarboxylate symporter
E0W69_004635	ENOG4105DQR	SNARE associated Golgi
E0W69_004640	ENOG4105D3Q	Sugar transferase
E0W69_004650	ENOG4108IAJ	Nad-dependent epimerase dehydratase
E0W69_004680	ENOG4107T8Q	Glycosyl transferase (Group 1
E0W69_004695	ENOG4107UU3	sucrose-phosphate synthase (EC 2.4.1.14)
E0W69_004700	ENOG4108Z90	colanic acid biosynthesis acetyltransferase wcaF
E0W69_004705	ENOG4106WTF	Glycosyl transferase, family 2
E0W69_004720	ENOG4106CD9	glycosyl transferase group 1
E0W69_004735	ENOG4105DR5	peptidase
E0W69_004740	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E0W69_004755	ENOG4108YYH	Nadph-dependent fmn reductase
E0W69_004760	ENOG4108Z4V	iron-sulfur cluster assembly
E0W69_004780	ENOG4105C9B	Cysteine desulfurase
E0W69_004785	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
E0W69_004790	ENOG4105VG1	fes assembly suf system protein
E0W69_004810	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
E0W69_004815	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
E0W69_004820	ENOG4105DKQ	ROK family
E0W69_004830	ENOG4105EYH	Exonuclease
E0W69_004835	ENOG4105C9U	ATP-dependent DNA helicase RecQ
E0W69_004845	ENOG41086DT	Membrane protein of unknown function
E0W69_004875	ENOG4107QRI	Phosphoketolase
E0W69_004880	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
E0W69_004900	ENOG4107SUZ	Sodium/hydrogen exchanger family
E0W69_004940	ENOG4105W5Q	DNA repair protein (RadC
E0W69_004980	ENOG4107TCE	N-acetyltransferase
E0W69_004990	ENOG4105D6J	arsenicaL-resistance protein
E0W69_005005	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E0W69_005020	ENOG4108KB1	transcriptional regulator, arac family
E0W69_005035	ENOG4105K70	DNA-binding protein
E0W69_005055	ENOG4105W5Q	DNA repair protein (RadC
E0W69_005090	ENOG4108JJA	ABC, transporter
E0W69_005160	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_005170	ENOG4105W5Q	DNA repair protein (RadC
E0W69_005225	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E0W69_005230	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E0W69_005240	ENOG4108HRK	Histidine kinase
E0W69_005245	ENOG4108VAC	response regulator
E0W69_005280	ENOG4108HRK	Histidine kinase
E0W69_005285	ENOG4108VAC	response regulator
E0W69_005295	ENOG4105DQ6	Transposase
E0W69_005310	ENOG4105DQ6	Transposase
E0W69_005340	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_005360	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
E0W69_005365	ENOG4107T0X	DNA ligase
E0W69_005370	ENOG4107T0X	DNA ligase
E0W69_005385	ENOG4105EKC	
E0W69_005395	ENOG4108QEY	Rhamnogalacturonate lyase
E0W69_005400	ENOG4107TDE	lipolytic protein G-D-S-L family
E0W69_005405	ENOG4105CBG	Sulfatase
E0W69_005415	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_005420	ENOG41061MV	Arylsulfatase
E0W69_005430	ENOG4105C5Q	Transcriptional regulator
E0W69_005440	ENOG41067V3	Antibiotic biosynthesis monooxygenase
E0W69_005470	ENOG4105CHH	sulfate transporter
E0W69_005490	ENOG4106HBX	Transcriptional Regulator AraC Family
E0W69_005495	ENOG4105WH1	Two component transcriptional regulator luxr family
E0W69_005500	ENOG4105GR3	Histidine kinase
E0W69_005520	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
E0W69_005525	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
E0W69_005530	ENOG4105DWF	phosphomethylpyrimidine kinase
E0W69_005540	ENOG4105DIJ	Phosphoethanolamine transferase
E0W69_005545	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
E0W69_005555	ENOG4107RGD	Major Facilitator superfamily
E0W69_005565	ENOG4105CQB	FAD linked oxidase domain protein
E0W69_005570	ENOG4105CHR	reductase
E0W69_005575	ENOG4105ID8	Transcriptional regulator, ARAC family
E0W69_005590	ENOG4105DY9	regulatoR
E0W69_005595	ENOG4108HRK	Histidine kinase
E0W69_005605	ENOG4108S01	response regulator
E0W69_005610	ENOG4108UW5	maltose o-acetyltransferase
E0W69_005655	ENOG4105BZU	Histidine kinase
E0W69_005665	ENOG4108RWN	rrna methyltransferase
E0W69_005670	ENOG4105DSY	exodeoxyribonuclease V, gamma
E0W69_005675	ENOG4105C9M	aspartyl-trna synthetase
E0W69_005700	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
E0W69_005705	ENOG4108IDZ	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
E0W69_005720	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
E0W69_005725	ENOG4105D2N	Aldolase
E0W69_005730	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E0W69_005745	ENOG4105DVY	radical SAM domain protein
E0W69_005750	ENOG4105DY9	regulatoR
E0W69_005755	ENOG4108HRK	Histidine kinase
E0W69_005765	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
E0W69_005770	ENOG4105CNU	cell division protein FtsK
E0W69_005785	ENOG4105NF4	modulator of drug activity
E0W69_005800	ENOG4105CFG	Acts as a chaperone (By similarity)
E0W69_005805	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E0W69_005810	ENOG41080IJ	Diacylglycerol kinase
E0W69_005855	ENOG4105K70	DNA-binding protein
E0W69_005860	ENOG4105CJJ	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress (By similarity)
E0W69_005890	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
E0W69_005915	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
E0W69_005935	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
E0W69_005945	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E0W69_005975	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
E0W69_005985	ENOG4105D1H	recombination factor protein RarA
E0W69_005995	ENOG4108BRW	Activates expression of the rhaSR operon in response to L-rhamnose (By similarity)
E0W69_006070	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
E0W69_006080	ENOG4105EW9	transcriptional regulator AsnC family
E0W69_006090	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
E0W69_006115	ENOG4105CHM	Aminotransferase
E0W69_006120	ENOG4105CKK	Glycosyl transferase, family 2
E0W69_006130	ENOG4105CD3	dihydroorotase
E0W69_006140	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E0W69_006190	ENOG4107ZT5	Thiol disulfide interchange protein
E0W69_006195	ENOG4105K70	DNA-binding protein
E0W69_006200	ENOG4105DFS	Conserved Protein
E0W69_006205	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E0W69_006215	ENOG4107J5P	Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC). Is also able to catalyze the hydrolysis of the thioester bond in palmitoyl-CoA in vitro (By similarity)
E0W69_006245	ENOG4105DY9	regulatoR
E0W69_006275	ENOG4105CX8	fg-gap repeat protein
E0W69_006300	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_006325	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_006335	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
E0W69_006340	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E0W69_006395	ENOG4108ZEY	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
E0W69_006405	ENOG4105EMN	RNA polymerase sigma factor
E0W69_006445	ENOG4105D70	Integrase catalytic subunit
E0W69_006450	ENOG4105F5W	AtP-binding protein
E0W69_006470	ENOG4108Z9K	Osmotically inducible protein
E0W69_006480	ENOG4105QNF	Outer membrane lipoprotein
E0W69_006490	ENOG4105KVH	Transcriptional regulator
E0W69_006515	ENOG4105D74	hydrolase
E0W69_006530	ENOG4105E1F	short-chain dehydrogenase reductase
E0W69_006540	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
E0W69_006560	ENOG4105WAB	arsR family transcriptional regulator
E0W69_006615	ENOG4105ID8	Transcriptional regulator, ARAC family
E0W69_006620	ENOG4105EMU	Dehydrogenase
E0W69_006625	ENOG4105KVH	Transcriptional regulator
E0W69_006640	ENOG4105CPC	Aldo Keto reductase
E0W69_006645	ENOG4105E1F	short-chain dehydrogenase reductase
E0W69_006685	ENOG4105NTD	Inherit from COG: Hydrolase
E0W69_006715	ENOG4105BZU	Histidine kinase
E0W69_006720	ENOG4105C08	Histidine kinase
E0W69_006730	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
E0W69_006745	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E0W69_006760	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E0W69_006770	ENOG4105C8Y	Acetylornithine aminotransferase
E0W69_006775	ENOG4105D01	(LipO)protein
E0W69_006780	ENOG4108UMI	ABC transporter, permease
E0W69_006790	ENOG4105E6M	Sulphatase-modifying factor protein
E0W69_006795	ENOG4105CKI	cobalamin synthesis protein
E0W69_006825	ENOG4106BRA	Membrane
E0W69_006830	ENOG4105EUB	pirin domain protein
E0W69_006845	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
E0W69_006850	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E0W69_006860	ENOG4105D06	uba thif-type nad fad binding protein
E0W69_006870	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
E0W69_006875	ENOG4105E0C	molybdate abc transporter
E0W69_006880	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
E0W69_006885	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
E0W69_006890	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
E0W69_006895	ENOG41080H2	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
E0W69_006915	ENOG4108R6W	Transcriptional regulator, ARAC family
E0W69_006945	ENOG4105DDI	hemolysin-type calcium-binding region
E0W69_006950	ENOG4105CWX	Alpha-1,2-mannosidase
E0W69_006955	ENOG4105ECR	NmrA family
E0W69_006965	ENOG4107SET	aldo keto reductase
E0W69_006970	ENOG4105DQ4	alcohol dehydrogenase
E0W69_006995	ENOG4105DQ4	alcohol dehydrogenase
E0W69_007000	ENOG4108M8W	Monooxygenase
E0W69_007030	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
E0W69_007040	ENOG4105CHR	reductase
E0W69_007065	ENOG4105E1F	short-chain dehydrogenase reductase
E0W69_007085	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
E0W69_007100	ENOG4105C2C	drug resistance transporter, Bcr CflA
E0W69_007105	ENOG4105F0F	Oxalate decarboxylase
E0W69_007130	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E0W69_007135	ENOG4105E0X	reductase
E0W69_007165	ENOG4108HRK	Histidine kinase
E0W69_007170	ENOG4108VAC	response regulator
E0W69_007185	ENOG4107GJV	short-chain dehydrogenase reductase
E0W69_007190	ENOG4105F27	Major Facilitator
E0W69_007205	ENOG4105C5H	ABC transporter
E0W69_007215	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
E0W69_007235	ENOG4105CTD	carboxy-peptidase
E0W69_007240	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
E0W69_007245	ENOG4105SFS	phosphoesterase RecJ domain protein
E0W69_007250	ENOG4108V1T	peptidylprolyl cis-trans isomerase
E0W69_007255	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
E0W69_007260	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
E0W69_007270	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
E0W69_007280	ENOG4105DVT	helicase
E0W69_007290	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
E0W69_007300	ENOG4105DWV	Homoserine O-trans-acetylase
E0W69_007305	ENOG41082T9	Membrane
E0W69_007310	ENOG4105CFH	Aspartokinase
E0W69_007320	ENOG4105CJ1	ABC, transporter
E0W69_007345	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
E0W69_007350	ENOG4107RA9	decarboxylase
E0W69_007370	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E0W69_007415	ENOG4108IND	Tetr family transcriptional regulator
E0W69_007425	ENOG4105KVH	Transcriptional regulator
E0W69_007430	ENOG4108SUT	Major Facilitator Superfamily
E0W69_007445	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E0W69_007455	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
E0W69_007465	ENOG4107SET	aldo keto reductase
E0W69_007470	ENOG4105CHR	reductase
E0W69_007475	ENOG4105W5Q	DNA repair protein (RadC
E0W69_007480	ENOG4105DZR	Type I site-specific deoxyribonuclease
E0W69_007490	ENOG4107UNZ	domain protein
E0W69_007505	ENOG4105CVR	type I restriction-modification system
E0W69_007560	ENOG4108WQI	RNA Polymerase
E0W69_007570	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_007625	ENOG4108NEV	two component transcriptional regulator, LytTR family
E0W69_007770	ENOG4107S5I	aldo keto reductase
E0W69_007830	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_007870	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_007875	ENOG4105ES5	Histidine kinase
E0W69_007880	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
E0W69_007890	ENOG4108HRK	Histidine kinase
E0W69_007895	ENOG4105DY9	regulatoR
E0W69_007905	ENOG4108VAC	response regulator
E0W69_007920	ENOG4105DQ6	Transposase
E0W69_007935	ENOG4105D2H	Uronic isomerase
E0W69_007950	ENOG4105CPQ	Dehydrogenase
E0W69_007965	ENOG4105CNT	hydrolase family 2
E0W69_007985	ENOG4105EE0	oxidoreductase
E0W69_008000	ENOG4105I82	acetyl xylan esterase
E0W69_008060	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_008070	ENOG4105CNT	hydrolase family 2
E0W69_008100	ENOG4105DET	Rhamnulokinase
E0W69_008105	ENOG4105C9F	isomerase
E0W69_008135	ENOG4108Z0Z	intracellular protease Pfpi family
E0W69_008140	ENOG4105CV8	reductase
E0W69_008175	ENOG4105CDU	Replicative dna helicase
E0W69_008190	ENOG4105C26	Dehydrogenase
E0W69_008200	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
E0W69_008210	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E0W69_008220	ENOG4105C0P	Mg chelatase subunit ChlI
E0W69_008240	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
E0W69_008245	ENOG4107PMW	Arabinan endo-1,5-alpha-L-arabinosidase
E0W69_008255	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
E0W69_008265	ENOG4105CGS	Alpha-glucosidase
E0W69_008280	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_008295	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
E0W69_008315	ENOG4105R3P	Inner membrane protein yagU
E0W69_008325	ENOG4105E9K	Isocitrate dehydrogenase
E0W69_008340	ENOG4108V06	Glutathione peroxidase
E0W69_008375	ENOG4105CHR	reductase
E0W69_008405	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_008430	ENOG4105C72	UPF0176 protein
E0W69_008460	ENOG4105ECJ	Glycosyl Transferase
E0W69_008515	ENOG4105W5Q	DNA repair protein (RadC
E0W69_008575	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E0W69_008580	ENOG4105K70	DNA-binding protein
E0W69_008605	ENOG4106P55	Transcriptional regulator
E0W69_008615	ENOG4105DJG	MaoC domain protein dehydratase
E0W69_008620	ENOG4105CYC	Transferase
E0W69_008625	ENOG4109025	Glyoxalase Bleomycin resistance protein (Dioxygenase
E0W69_008635	ENOG4105CHR	reductase
E0W69_008640	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
E0W69_008650	ENOG4107XGZ	Hydrolase
E0W69_008655	ENOG4105F5W	AtP-binding protein
E0W69_008660	ENOG4105D70	Integrase catalytic subunit
E0W69_008685	ENOG4105W5Q	DNA repair protein (RadC
E0W69_008740	ENOG4108JJA	ABC, transporter
E0W69_008750	ENOG4105D70	Integrase catalytic subunit
E0W69_008755	ENOG4105F5W	AtP-binding protein
E0W69_008790	ENOG4105DFS	Conserved Protein
E0W69_008815	ENOG4107ZT5	Thiol disulfide interchange protein
E0W69_008830	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_008860	ENOG4105W5Q	DNA repair protein (RadC
E0W69_008915	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E0W69_008930	ENOG4108KB1	transcriptional regulator, arac family
E0W69_008945	ENOG4105K70	DNA-binding protein
E0W69_008965	ENOG4105W5Q	DNA repair protein (RadC
E0W69_009005	ENOG4108JJA	ABC, transporter
E0W69_009075	ENOG4107TDE	lipolytic protein G-D-S-L family
E0W69_009080	ENOG4105CX8	fg-gap repeat protein
E0W69_009090	ENOG4107TDE	lipolytic protein G-D-S-L family
E0W69_009105	ENOG4105ETE	Transcriptional regulator (LacI family
E0W69_009130	ENOG4105F5H	Glycosyl Hydrolase Family 88
E0W69_009135	ENOG4107QZW	Altronate oxidoreductase
E0W69_009140	ENOG4105CTX	dehydratase
E0W69_009145	ENOG4105D2H	Uronic isomerase
E0W69_009160	ENOG4105DJB	Major Facilitator Superfamily
E0W69_009165	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
E0W69_009190	ENOG41067QW	Transcriptional regulator
E0W69_009265	ENOG4105CFI	type iii restriction protein res subunit
E0W69_009280	ENOG4105CDU	Replicative dna helicase
E0W69_009555	ENOG4105W5Q	DNA repair protein (RadC
E0W69_009560	ENOG4105DZR	Type I site-specific deoxyribonuclease
E0W69_009565	ENOG4105CB5	ATP-dependent DNA helicase recG
E0W69_009580	ENOG4105CVR	type I restriction-modification system
E0W69_009640	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_009655	ENOG4105ID8	Transcriptional regulator, ARAC family
E0W69_009785	ENOG4105ID8	Transcriptional regulator, ARAC family
E0W69_009790	ENOG4108RU0	short-chain dehydrogenase reductase
E0W69_009795	ENOG4105ID8	Transcriptional regulator, ARAC family
E0W69_009800	ENOG4105EMU	Dehydrogenase
E0W69_009840	ENOG4108NEV	two component transcriptional regulator, LytTR family
E0W69_009860	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E0W69_009925	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
E0W69_009935	ENOG4105D06	uba thif-type nad fad binding protein
E0W69_009955	ENOG4105C3J	Cysteine desulfurase
E0W69_009960	ENOG4105CHR	reductase
E0W69_009970	ENOG4105CHR	reductase
E0W69_010025	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
E0W69_010045	ENOG4105BZ1	(ABC) transporter
E0W69_010055	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
E0W69_010060	ENOG4105C5Z	peptidase
E0W69_010065	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
E0W69_010070	ENOG4107R0I	Cell wall formation (By similarity)
E0W69_010075	ENOG41084M5	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
E0W69_010080	ENOG4108KPZ	tonB-dependent Receptor
E0W69_010085	ENOG4105D3R	alkyl hydroperoxide reductase
E0W69_010090	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
E0W69_010105	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
E0W69_010110	ENOG4105EAA	nucleoside
E0W69_010135	ENOG4108Z7F	N-acetyltransferase
E0W69_010145	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E0W69_010160	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_010195	ENOG4106210	phosphatase activity
E0W69_010200	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
E0W69_010210	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
E0W69_010225	ENOG4105EAC	phosphoserine phosphatase
E0W69_010230	ENOG4105DND	Transcriptional regulator
E0W69_010235	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E0W69_010255	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E0W69_010285	ENOG4107FQX	Alpha-acetolactate decarboxylase
E0W69_010290	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
E0W69_010295	ENOG4107QR9	Iron-sulfur cluster binding protein
E0W69_010305	ENOG4105K4T	epimerase
E0W69_010310	ENOG4105EMU	Dehydrogenase
E0W69_010325	ENOG4107QXV	Phosphate transporter
E0W69_010350	ENOG4105K64	Glycosyl transferase, family 2
E0W69_010370	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
E0W69_010380	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
E0W69_010385	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
E0W69_010390	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
E0W69_010395	ENOG4105DQ4	alcohol dehydrogenase
E0W69_010400	ENOG4105XA0	heptosyltransferase ii
E0W69_010425	ENOG4107QKV	phosphomannomutase
E0W69_010430	ENOG4107QI6	Cysteine desulfurase
E0W69_010440	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
E0W69_010445	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
E0W69_010450	ENOG4105D3G	Pseudouridine synthase
E0W69_010460	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
E0W69_010480	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
E0W69_010505	ENOG4107SUZ	Sodium/hydrogen exchanger family
E0W69_010520	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
E0W69_010525	ENOG4105CTX	dehydratase
E0W69_010530	ENOG4105CHR	reductase
E0W69_010540	ENOG4105ERH	Fumarylacetoacetate hydrolase
E0W69_010545	ENOG4108R85	Short chain dehydrogenase
E0W69_010550	ENOG4105QJH	Domain of unknown function (DUF718)
E0W69_010555	ENOG4105EDR	glucose galactose transporter
E0W69_010565	ENOG4105C19	ABC transporter
E0W69_010575	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E0W69_010580	ENOG4107RBB	ABC transporter, permease
E0W69_010590	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E0W69_010595	ENOG4107RBB	ABC transporter, permease
E0W69_010605	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E0W69_010615	ENOG4105C19	ABC transporter
E0W69_010620	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E0W69_010625	ENOG4107RBB	ABC transporter, permease
E0W69_010630	ENOG4107RBB	ABC transporter, permease
E0W69_010650	ENOG4105BZU	Histidine kinase
E0W69_010665	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_010690	ENOG4105CNT	hydrolase family 2
E0W69_010720	ENOG4105CGP	Urocanate hydratase
E0W69_010730	ENOG4105C84	Histidine ammonia-lyase
E0W69_010735	ENOG4107RSM	transcriptional regulator
E0W69_010790	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_010815	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_010835	ENOG4105CNT	hydrolase family 2
E0W69_010850	ENOG4107QMZ	Dehydrogenase
E0W69_010860	ENOG4107R7I	amino acid
E0W69_010865	ENOG4105CTU	Proline racemase
E0W69_010875	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
E0W69_010885	ENOG4105EE6	Alcohol dehydrogenase zinc-binding domain protein
E0W69_010890	ENOG4105E1F	short-chain dehydrogenase reductase
E0W69_010935	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
E0W69_010940	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
E0W69_011005	ENOG4107QTF	adenylosuccinate lyase
E0W69_011015	ENOG4105FBJ	fumarylacetoacetate (faa) hydrolase
E0W69_011025	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
E0W69_011030	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E0W69_011040	ENOG4105DA6	Catalyzes the conversion of 5-methoxyuridine (mo5U) to uridine-5-oxyacetic acid (cmo5U) at position 34 in tRNA. May also participate in the methylation of uridine-5-oxyacetic acid (cmo5U) to uridine-5-oxyacetic acid methyl ester (mcmo5U) (By similarity)
E0W69_011045	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
E0W69_011050	ENOG4105DKW	ABC transporter
E0W69_011055	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
E0W69_011060	ENOG4105C01	Dihydroxy-acid dehydratase
E0W69_011065	ENOG4105C7K	acetolactate synthase
E0W69_011070	ENOG4108ZP8	Acetolactate synthase small subunit
E0W69_011075	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
E0W69_011085	ENOG4105C7B	Threonine dehydratase
E0W69_011090	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
E0W69_011100	ENOG4105E2K	Glycosyl transferase (Group 1
E0W69_011115	ENOG4105CG5	Glycosyl transferase (Group 1
E0W69_011130	ENOG4105EXC	Acyl-transferase
E0W69_011135	ENOG4105K64	Glycosyl transferase, family 2
E0W69_011150	ENOG4107S6X	Glycosyl transferase, family 2
E0W69_011170	ENOG4107YYJ	Glycosyl transferase, family 2
E0W69_011175	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
E0W69_011180	ENOG4105C7K	acetolactate synthase
E0W69_011185	ENOG4108SMP	Nad-dependent epimerase dehydratase
E0W69_011190	ENOG4105FAW	cDP-glucose 4,6-dehydratase
E0W69_011195	ENOG4105EJZ	Glucose-1-phosphate cytidylyltransferase
E0W69_011210	ENOG4107QQG	Dehydrogenase
E0W69_011215	ENOG4105D75	Capsular exopolysaccharide family
E0W69_011225	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
E0W69_011230	ENOG4105KG3	cytidine deaminase
E0W69_011235	ENOG4108Y6J	UPF0403 protein
E0W69_011240	ENOG4105VN1	Heat shock protein
E0W69_011245	ENOG4107QKA	exodeoxyribonuclease V beta
E0W69_011250	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
E0W69_011275	ENOG4105FQP	Beta-lactamase
E0W69_011280	ENOG4105C9K	Endothelin-converting enzyme 1
E0W69_011335	ENOG4105C30	Nad-dependent epimerase dehydratase
E0W69_011355	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E0W69_011365	ENOG4105EMU	Dehydrogenase
E0W69_011370	ENOG4107QSV	RmuC domain protein
E0W69_011390	ENOG4105E33	succinate dehydrogenase
E0W69_011410	ENOG4105BZS	acriflavin resistance protein
E0W69_011440	ENOG4105C3F	Signal peptidase i
E0W69_011445	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
E0W69_011465	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
E0W69_011475	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
E0W69_011480	ENOG4105D49	3-dehydroquinate synthase
E0W69_011485	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
E0W69_011505	ENOG4105CQC	Prephenate dehydratase
E0W69_011515	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
E0W69_011525	ENOG4105C6K	Malic enzyme
E0W69_011530	ENOG4105CH2	amidohydrolase
E0W69_011535	ENOG4105C5W	Aldolase
E0W69_011560	ENOG4105C6E	dna polymerase iii
E0W69_011570	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
E0W69_011585	ENOG4105E05	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E0W69_011595	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
E0W69_011630	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
E0W69_011635	ENOG4105CTQ	phosphohexokinase
E0W69_011640	ENOG4105CA9	Pyruvate kinase
E0W69_011650	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
E0W69_011655	ENOG4107SUZ	Sodium/hydrogen exchanger family
E0W69_011665	ENOG4105CWX	Alpha-1,2-mannosidase
E0W69_011670	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
E0W69_011675	ENOG4105BZU	Histidine kinase
E0W69_011695	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
E0W69_011700	ENOG4105CGH	5'-nucleotidase
E0W69_011705	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
E0W69_011710	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
E0W69_011715	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
E0W69_011725	ENOG4105D5D	udp-galactopyranose mutase
E0W69_011735	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
E0W69_011740	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
E0W69_011755	ENOG4108RT7	Glycosyl transferase, family 2
E0W69_011775	ENOG4105H63	Glycosyl transferase, family 2
E0W69_011790	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
E0W69_011795	ENOG4105D75	Capsular exopolysaccharide family
E0W69_011820	ENOG4107QI1	Mate efflux family protein
E0W69_011825	ENOG4105C25	Primosomal protein n'
E0W69_011830	ENOG4105KA0	thioesterase Superfamily protein
E0W69_011845	ENOG4105CVP	deoxyribo-dipyrimidine photolyase
E0W69_011855	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
E0W69_011860	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
E0W69_011885	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
E0W69_011890	ENOG4105CGZ	zinc metallopeptidase
E0W69_011900	ENOG41083X6	30S ribosomal protein S21
E0W69_011905	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E0W69_011910	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
E0W69_011915	ENOG4105DEU	major facilitator superfamily
E0W69_011920	ENOG41081WG	50s ribosomal protein l31
E0W69_011925	ENOG4108JQ1	Dehydrogenase
E0W69_011985	ENOG4105CEY	Amp-dependent synthetase and ligase
E0W69_011995	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
E0W69_012000	ENOG4106AM8	polysaccharide lyase family 8
E0W69_012005	ENOG4105EP8	Glycosyl Hydrolase Family 88
E0W69_012045	ENOG4105EDR	glucose galactose transporter
E0W69_012060	ENOG4107QYX	exodeoxyribonuclease v alpha
E0W69_012070	ENOG4108KF3	Electron transport protein SCO1 SenC
E0W69_012075	ENOG4107RQ2	Cytochrome c oxidase, subunit I
E0W69_012080	ENOG4107RQ2	Cytochrome c oxidase, subunit I
E0W69_012095	ENOG4105WH1	Two component transcriptional regulator luxr family
E0W69_012110	ENOG4105CN1	protease
E0W69_012115	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
E0W69_012120	ENOG4107SN7	NLP P60 protein
E0W69_012125	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
E0W69_012130	ENOG4105C79	DNA protecting protein DprA
E0W69_012155	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
E0W69_012160	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
E0W69_012175	ENOG4105CPP	Dehydrogenase, E1 component
E0W69_012180	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
E0W69_012195	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
E0W69_012225	ENOG4105C6T	cysteine synthase
E0W69_012230	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
E0W69_012235	ENOG4105DF5	DNA topoisomerase IV, subunit A
E0W69_012240	ENOG4108YZK	glyoxalase bleomycin resistance protein dioxygenase
E0W69_012250	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
E0W69_012275	ENOG4105E2X	shikimate dehydrogenase
E0W69_012290	ENOG4105CHU	acetyl-coa acetyltransferase
E0W69_012295	ENOG4105C1G	acyl-Coa dehydrogenase
E0W69_012300	ENOG4105BZJ	Electron transfer flavoprotein
E0W69_012305	ENOG4105C10	Electron transfer flavoprotein
E0W69_012310	ENOG4108IQE	Amp-dependent synthetase and ligase
E0W69_012360	ENOG4105C26	Dehydrogenase
E0W69_012385	ENOG4105DEN	Luciferase family
E0W69_012400	ENOG4105CT7	inner membrane cred family protein
E0W69_012405	ENOG4105CPP	Dehydrogenase, E1 component
E0W69_012410	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
E0W69_012420	ENOG4105DJV	ribulose-phosphate 3-epimerase
E0W69_012430	ENOG4108IND	Tetr family transcriptional regulator
E0W69_012435	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
E0W69_012440	ENOG4107XZQ	multidrug resistance protein
E0W69_012445	ENOG41067SE	Tetr family transcriptional regulator
E0W69_012505	ENOG4105DA2	glyoxalase bleomycin resistance protein dioxygenase
E0W69_012525	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
E0W69_012530	ENOG4105C0B	DNA polymerase III (alpha subunit)
E0W69_012550	ENOG4105DQ4	alcohol dehydrogenase
E0W69_012570	ENOG4105DEI	Mannitol dehydrogenase
E0W69_012575	ENOG4105W3H	MtN3 and saliva related transmembrane protein
E0W69_012580	ENOG4105DGW	oligopeptidase A
E0W69_012600	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
E0W69_012605	ENOG4105BZA	Phosphoglycerate kinase
E0W69_012615	ENOG4105FJR	Lmbe family
E0W69_012635	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
E0W69_012645	ENOG4105DTN	riboflavin biosynthesis protein ribF
E0W69_012650	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
E0W69_012665	ENOG4105ETE	Transcriptional regulator (LacI family
E0W69_012670	ENOG4108KPW	sugar kinase
E0W69_012675	ENOG4107TTA	Xylose isomerase domain protein TIM barrel
E0W69_012690	ENOG4105DU1	integral membrane protein, terc
E0W69_012730	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
E0W69_012740	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
E0W69_012745	ENOG4105ED7	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling (By similarity)
E0W69_012755	ENOG4105CPN	adenine deaminase
E0W69_012760	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
E0W69_012765	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_012770	ENOG4105TT1	Ragb susd domain-containing protein
E0W69_012785	ENOG4105VEJ	Heat shock protein
E0W69_012810	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
E0W69_012815	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
E0W69_012820	ENOG4105BZ1	(ABC) transporter
E0W69_012825	ENOG4105FQP	Beta-lactamase
E0W69_012830	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
E0W69_012835	ENOG4105CP7	Triose-phosphate isomerase
E0W69_012870	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
E0W69_012880	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
E0W69_012890	ENOG4105EQ0	Major Facilitator superfamily
E0W69_012920	ENOG4105CSA	Coproporphyrinogen iii oxidase
E0W69_012925	ENOG4108UQS	dipeptidase
E0W69_012935	ENOG4105C9X	ppx gppa phosphatase
E0W69_012945	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
E0W69_012950	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
E0W69_012960	ENOG4105CIH	Imidazole acetol-phosphate transaminase
E0W69_012975	ENOG4105VFU	Rna-binding protein
E0W69_012980	ENOG4105E2D	ec 3.2.1.52
E0W69_012990	ENOG4105DFA	alanine racemase domain protein
E0W69_013010	ENOG4105CPC	Aldo Keto reductase
E0W69_013015	ENOG4107RH7	Nicotinate phosphoribosyltransferase
E0W69_013025	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
E0W69_013035	ENOG4108R99	pseudouridine synthase
E0W69_013040	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
E0W69_013045	ENOG4108UJD	30S ribosomal protein S9
E0W69_013050	ENOG4105CE9	30S ribosomal protein S2
E0W69_013055	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
E0W69_013085	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
E0W69_013090	ENOG4105D60	lipoprotein releasing system transmembrane protein
E0W69_013100	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
E0W69_013110	ENOG4107YAY	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
E0W69_013140	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_013160	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
E0W69_013170	ENOG4105D52	delta-aminolevulinic acid dehydratase
E0W69_013175	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
E0W69_013180	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
E0W69_013190	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
E0W69_013195	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
E0W69_013215	ENOG4108Z6B	deaminase
E0W69_013220	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
E0W69_013225	ENOG4105DTQ	mandelate racemase muconate lactonizing
E0W69_013230	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
E0W69_013240	ENOG4108IU3	tonb-dependent siderophore receptor
E0W69_013255	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
E0W69_013285	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
E0W69_013295	ENOG4105EMN	RNA polymerase sigma factor
E0W69_013310	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
E0W69_013325	ENOG4105ECP	epimerase
E0W69_013335	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
E0W69_013350	ENOG4105TT1	Ragb susd domain-containing protein
E0W69_013355	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_013380	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
E0W69_013390	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
E0W69_013400	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
E0W69_013410	ENOG4105SYT	Methylenetetrahydrofolate reductase
E0W69_013430	ENOG4105U5Y	Transcriptional regulator
E0W69_013435	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
E0W69_013440	ENOG4105DXN	mazG family
E0W69_013445	ENOG4108HWS	Histidine kinase
E0W69_013480	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
E0W69_013485	ENOG4105CI2	imidazolone-5-propionate hydrolase
E0W69_013490	ENOG4105VFF	UPF0102 protein
E0W69_013495	ENOG4105EIP	mannose-6-phosphate isomerase
E0W69_013505	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
E0W69_013550	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
E0W69_013555	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
E0W69_013560	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
E0W69_013570	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E0W69_013575	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
E0W69_013595	ENOG4105VTR	Integrase
E0W69_013620	ENOG4105DZR	Type I site-specific deoxyribonuclease
E0W69_013625	ENOG4107R3N	Filamentation induced by cAMP protein fic
E0W69_013635	ENOG4105CB5	ATP-dependent DNA helicase recG
E0W69_013650	ENOG4105CVR	type I restriction-modification system
E0W69_013715	ENOG4105KT5	UmuD protein
E0W69_013740	ENOG4108NEV	two component transcriptional regulator, LytTR family
E0W69_013785	ENOG4105D70	Integrase catalytic subunit
E0W69_013790	ENOG4105F5W	AtP-binding protein
E0W69_013810	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_013855	ENOG4105CUB	amino acid
E0W69_013865	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
E0W69_013870	ENOG4107QP8	phosphohexose isomerase
E0W69_013930	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
E0W69_013950	ENOG41074B2	UPF0747 protein
E0W69_013955	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
E0W69_013980	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_013985	ENOG4105E2R	ROK family
E0W69_013995	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
E0W69_014025	ENOG4105W5Q	DNA repair protein (RadC
E0W69_014035	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E0W69_014040	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
E0W69_014045	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
E0W69_014050	ENOG4105EM2	membrane
E0W69_014065	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
E0W69_014075	ENOG4105C22	threonyL-tRNA synthetase
E0W69_014080	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
E0W69_014090	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
E0W69_014095	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
E0W69_014130	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
E0W69_014140	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
E0W69_014145	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
E0W69_014150	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
E0W69_014155	ENOG4105CHV	Transcription elongation factor NusA
E0W69_014160	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
E0W69_014200	ENOG4105C0B	DNA polymerase III (alpha subunit)
E0W69_014210	ENOG4108QBX	(LipO)protein
E0W69_014220	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
E0W69_014225	ENOG4105T7Q	H transporting two-sector ATPase delta epsilon subunit
E0W69_014230	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
E0W69_014245	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E0W69_014250	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E0W69_014255	ENOG4105DCI	Phosphohydrolase
E0W69_014260	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E0W69_014275	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
E0W69_014285	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
E0W69_014295	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
E0W69_014300	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E0W69_014315	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
E0W69_014320	ENOG4108KNB	n-acetylmuramoyl-l-alanine amidase
E0W69_014345	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
E0W69_014350	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
E0W69_014370	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
E0W69_014375	ENOG4105C7Z	Conserved Protein
E0W69_014385	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
E0W69_014390	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E0W69_014395	ENOG4108KJP	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
E0W69_014405	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
E0W69_014425	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E0W69_014440	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_014460	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_014470	ENOG4105DU6	RNA polymerase
E0W69_014545	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_014585	ENOG4105CNT	hydrolase family 2
E0W69_014590	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
E0W69_014595	ENOG4105EX0	alpha-galactosidase
E0W69_014600	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
E0W69_014610	ENOG4105DFY	n-acylglucosamine 2-epimerase
E0W69_014615	ENOG4105HY2	Glycosidase related protein
E0W69_014620	ENOG4105CT4	transporter
E0W69_014635	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_014650	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_014655	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
E0W69_014675	ENOG4105F8V	Hydrolase, tatD family
E0W69_014715	ENOG4105CPC	Aldo Keto reductase
E0W69_014725	ENOG4105D9R	oxidoreductase
E0W69_014765	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
E0W69_014775	ENOG4105DWF	phosphomethylpyrimidine kinase
E0W69_014805	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
E0W69_014830	ENOG4105DZ2	Transcriptional regulator
E0W69_014855	ENOG4107SUZ	Sodium/hydrogen exchanger family
E0W69_014885	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
E0W69_014895	ENOG4105DEG	Vwa containing coxe family protein
E0W69_014905	ENOG4105DUX	Transporter
E0W69_014910	ENOG4105C12	Phosphoribosylglycinamide synthetase
E0W69_014920	ENOG4105DFF	Rod shape-determining protein mreb
E0W69_014935	ENOG4105CJN	penicillin-binding protein
E0W69_014940	ENOG4105CNI	cell division protein FtsW
E0W69_014945	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
E0W69_014965	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
E0W69_014980	ENOG4107T6X	nag kinase
E0W69_015035	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E0W69_015050	ENOG4105VMP	Transcriptional regulator
E0W69_015065	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E0W69_015075	ENOG4105DVH	amino acid
E0W69_015100	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
E0W69_015105	ENOG4105C34	Pseudouridine synthase
E0W69_015120	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
E0W69_015145	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E0W69_015195	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
E0W69_015200	ENOG4107UUG	Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins (By similarity)
E0W69_015210	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
E0W69_015215	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
E0W69_015225	ENOG4105M08	Membrane
E0W69_015230	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
E0W69_015235	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
E0W69_015245	ENOG4107TPS	domain protein
E0W69_015255	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
E0W69_015260	ENOG4105KME	endoribonuclease L-psp
E0W69_015270	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
E0W69_015280	ENOG4105D05	Receptor
E0W69_015305	ENOG4105CN1	protease
E0W69_015310	ENOG4108S4H	thioesterase Superfamily protein
E0W69_015315	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E0W69_015325	ENOG4105CHR	reductase
E0W69_015345	ENOG4105E1F	short-chain dehydrogenase reductase
E0W69_015350	ENOG4105FTV	AraC Family Transcriptional Regulator
E0W69_015370	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
E0W69_015375	ENOG4105UNS	Pfam:DUF419
E0W69_015380	ENOG4105E5K	Alpha-amylase
E0W69_015395	ENOG4105D6E	homoserine dehydrogenase
E0W69_015400	ENOG4105DWV	Homoserine O-trans-acetylase
E0W69_015405	ENOG4105KCK	Peptidoglycan-associated lipoprotein
E0W69_015415	ENOG4106HB6	Alpha beta hydrolase
E0W69_015425	ENOG4105KTH	gatB Yqey
E0W69_015440	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E0W69_015445	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
E0W69_015460	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
E0W69_015480	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
E0W69_015495	ENOG4105CRK	lysyL-tRNA synthetase
E0W69_015510	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
E0W69_015515	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E0W69_015520	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
E0W69_015525	ENOG4107YB6	acetyltransferase, (GNAT) family
E0W69_015540	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_015555	ENOG4105BZP	glycoside hydrolase 15-related
E0W69_015560	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
E0W69_015565	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
E0W69_015570	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
E0W69_015575	ENOG4105C7S	Dehydrogenase
E0W69_015580	ENOG4107R6T	Involved in the transcription termination process (By similarity)
E0W69_015590	ENOG4105VIE	preprotein translocase, subunit YajC
E0W69_015595	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
E0W69_015600	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
E0W69_015620	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
E0W69_015625	ENOG410853W	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E0W69_015630	ENOG4105C19	ABC transporter
E0W69_015640	ENOG4105C7K	acetolactate synthase
E0W69_015650	ENOG4105CKW	Inner membrane protein yedI
E0W69_015665	ENOG4105CPQ	Dehydrogenase
E0W69_015670	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
E0W69_015680	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
E0W69_015700	ENOG4105DCG	PHP domain protein
E0W69_015710	ENOG4105CSH	Transporter
E0W69_015715	ENOG4105CSM	endonuclease III
E0W69_015725	ENOG4105EMN	RNA polymerase sigma factor
E0W69_015735	ENOG4105FFC	UPF0187 protein
E0W69_015740	ENOG4105GR3	Histidine kinase
E0W69_015745	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
E0W69_015785	ENOG4105EZR	dyp-type peroxidase family protein
E0W69_015800	ENOG4108Z9K	Osmotically inducible protein
E0W69_015805	ENOG4107SUZ	Sodium/hydrogen exchanger family
E0W69_015830	ENOG4107YBY	Hydrolase
E0W69_015835	ENOG4105E66	phosphoriboisomerase A
E0W69_015840	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
E0W69_015845	ENOG4105KNE	Phosphatidate cytidylyltransferase
E0W69_015855	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
E0W69_015890	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
E0W69_015900	ENOG4105CHJ	isochorismatase hydrolase
E0W69_015915	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
E0W69_015925	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
E0W69_015935	ENOG4108RMU	ferritin dps family protein
E0W69_016005	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
E0W69_016020	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
E0W69_016040	ENOG4105KVH	Transcriptional regulator
E0W69_016045	ENOG4105F27	Major Facilitator
E0W69_016080	ENOG4105EA8	2-Nitropropane dioxygenase
E0W69_016090	ENOG4105DGW	oligopeptidase A
E0W69_016095	ENOG4105C8Y	Acetylornithine aminotransferase
E0W69_016130	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
E0W69_016160	ENOG4105F4G	Membrane
E0W69_016165	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
E0W69_016170	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
E0W69_016245	ENOG4108JA2	transcriptioN-repair coupling factor
E0W69_016265	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
E0W69_016270	ENOG4105EHZ	conserved protein UCP016719
E0W69_016290	ENOG4105CAY	ferredoxin--nadp reductase
E0W69_016295	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
E0W69_016300	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
E0W69_016315	ENOG4105CMG	Carbohydrate kinase
E0W69_016325	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E0W69_016365	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
E0W69_016370	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
E0W69_016375	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
E0W69_016390	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
E0W69_016395	ENOG4108HHA	Transketolase
E0W69_016415	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
E0W69_016450	ENOG4105C9Q	fumarate hydratase class II
E0W69_016460	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
E0W69_016470	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
E0W69_016530	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
E0W69_016535	ENOG4105D7N	magnesium and cobalt transport protein CorA
E0W69_016540	ENOG4107QUV	Domain protein
E0W69_016590	ENOG4105DCF	alanine dehydrogenase
E0W69_016600	ENOG4105C8X	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
E0W69_016605	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
E0W69_016615	ENOG4105C37	(CBS) domain
E0W69_016620	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
E0W69_016630	ENOG4105ECY	inositol monophosphatase
E0W69_016635	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
E0W69_016645	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
E0W69_016660	ENOG4105CJ1	ABC, transporter
E0W69_016675	ENOG4107R3N	Filamentation induced by cAMP protein fic
E0W69_016680	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
E0W69_016700	ENOG4107ZSV	Receptor
E0W69_016715	ENOG4107REN	Carbamoyltransferase
E0W69_016730	ENOG4105C1G	acyl-Coa dehydrogenase
E0W69_016755	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_016765	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E0W69_016770	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E0W69_016775	ENOG4108XC3	NADH ubiquinone oxidoreductase
E0W69_016780	ENOG41080TC	multidrug resistance protein
E0W69_016795	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
E0W69_016805	ENOG4105CPC	Aldo Keto reductase
E0W69_016810	ENOG4105C6Z	Gluconate
E0W69_016840	ENOG4105C5S	asparaginyl-tRNA synthetase
E0W69_016855	ENOG4105M6F	mutator MutT protein
E0W69_016905	ENOG4105FAT	Acyl-transferase
E0W69_016910	ENOG4105C2J	ABC transporter
E0W69_016915	ENOG4108FN7	Aldo keto reductase
E0W69_016940	ENOG4105EEI	dihydropteroate synthase
E0W69_016975	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
E0W69_016980	ENOG4105ESV	Glycosyl transferase, family 4
E0W69_016985	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
E0W69_017015	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
E0W69_017025	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
E0W69_017030	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
E0W69_017035	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
E0W69_017045	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
E0W69_017065	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
E0W69_017100	ENOG4105CD3	dihydroorotase
E0W69_017135	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E0W69_017155	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
E0W69_017160	ENOG4107TCE	N-acetyltransferase
E0W69_017180	ENOG4107ZT5	Thiol disulfide interchange protein
E0W69_017185	ENOG4108NEV	two component transcriptional regulator, LytTR family
E0W69_017190	ENOG4108HRK	Histidine kinase
E0W69_017200	ENOG4105VFU	Rna-binding protein
E0W69_017205	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
E0W69_017215	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
E0W69_017220	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
E0W69_017225	ENOG4105VN1	Heat shock protein
E0W69_017230	ENOG4105CH6	catalase
E0W69_017265	ENOG4105W5Q	DNA repair protein (RadC
E0W69_017340	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_017365	ENOG4105DFS	Conserved Protein
E0W69_017390	ENOG4108R6K	riboflavin synthase, subunit alpha
E0W69_017395	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
E0W69_017420	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
E0W69_017435	ENOG4105C8N	cysteinyl-tRNA synthetase
E0W69_017440	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
E0W69_017445	ENOG4105K6T	rare lipoprotein A
E0W69_017465	ENOG4105CAK	Cell division ATP-binding protein ftsE
E0W69_017470	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
E0W69_017495	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
E0W69_017505	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
E0W69_017510	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
E0W69_017520	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
E0W69_017530	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
E0W69_017535	ENOG4105VQD	rieske 2fe-2S domain-containing protein
E0W69_017555	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_017575	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_017585	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_017600	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
E0W69_017610	ENOG4105DY9	regulatoR
E0W69_017635	ENOG4107URF	beta-phospho-glucomutase
E0W69_017640	ENOG4108IUK	alpha amylase, catalytic
E0W69_017655	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_017660	ENOG4105ETE	Transcriptional regulator (LacI family
E0W69_017680	ENOG4105EGD	dinuclear metal center protein, YbgI family
E0W69_017690	ENOG4105E63	Pfam:DUF178
E0W69_017695	ENOG4107TIF	Phenazine biosynthesis protein, PhzF family
E0W69_017700	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
E0W69_017715	ENOG4105EUJ	GTP cyclohydrolase i
E0W69_017725	ENOG4105C10	Electron transfer flavoprotein
E0W69_017730	ENOG4105TPV	
E0W69_017740	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
E0W69_017755	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
E0W69_017765	ENOG4105NWN	ApaG protein
E0W69_017780	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
E0W69_017785	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
E0W69_017805	ENOG4105EJQ	L-serine dehydratase
E0W69_017840	ENOG4105EN6	Membrane
E0W69_017845	ENOG4105DWT	malate dehydrogenase (quinone)
E0W69_017850	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
E0W69_017855	ENOG410864M	50S ribosomal protein L36
E0W69_017860	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
E0W69_017865	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
E0W69_017870	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
E0W69_017875	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E0W69_017880	ENOG4108ZT0	50S ribosomal protein l17
E0W69_017895	ENOG4105BZ1	(ABC) transporter
E0W69_017905	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
E0W69_017925	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E0W69_017930	ENOG4108WBT	adenosyltransferase
E0W69_017940	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
E0W69_017950	ENOG4107SFQ	iron-sulfur binding
E0W69_017975	ENOG4105Z4T	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
E0W69_017980	ENOG4105BZ9	Cytochrome C oxidase, subunit I
E0W69_017985	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
E0W69_017990	ENOG4105CCU	oxidase (Subunit III)
E0W69_017995	ENOG4107QS1	Cytochrome C Oxidase, Subunit III
E0W69_018025	ENOG4105D9R	oxidoreductase
E0W69_018045	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
E0W69_018050	ENOG4105E98	transcriptional regulator DeoR family
E0W69_018055	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
E0W69_018060	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
E0W69_018075	ENOG4108YYX	Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. Modulates RNA-binding and helicase activities of the degradosome (By similarity)
E0W69_018080	ENOG4108VVK	transcriptional Regulator, AsnC
E0W69_018090	ENOG4105DA4	cytochrome c-type biogenesis protein
E0W69_018110	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
E0W69_018120	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_018145	ENOG4107TE5	Lipid kinase
E0W69_018160	ENOG4105W2Z	cytochrome C, class I
E0W69_018165	ENOG4105CHM	Aminotransferase
E0W69_018180	ENOG4105E0X	reductase
E0W69_018195	ENOG4105CEU	Arginine dihydrolase
E0W69_018205	ENOG4105CE1	Ferrous iron transport protein b
E0W69_018215	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
E0W69_018220	ENOG4108Z7F	N-acetyltransferase
E0W69_018235	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E0W69_018270	ENOG4105IRK	Glycosyl transferase (Group 1
E0W69_018295	ENOG4105BZ1	(ABC) transporter
E0W69_018325	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
E0W69_018340	ENOG4107USA	Thioredoxin
E0W69_018355	ENOG4105EIE	fructose-bisphosphate aldolase
E0W69_018365	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
E0W69_018370	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
E0W69_018375	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
E0W69_018380	ENOG41082S5	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
E0W69_018385	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
E0W69_018390	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
E0W69_018395	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
E0W69_018400	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
E0W69_018405	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
E0W69_018410	ENOG4108628	50s ribosomal protein l29
E0W69_018415	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
E0W69_018420	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
E0W69_018425	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
E0W69_018430	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
E0W69_018435	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
E0W69_018440	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
E0W69_018445	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
E0W69_018450	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
E0W69_018455	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
E0W69_018460	ENOG41084HK	50S ribosomal protein L30
E0W69_018465	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
E0W69_018470	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
E0W69_018480	ENOG4105CBX	hi0933 family
E0W69_018500	ENOG4105DFK	Polyphosphate glucokinase
E0W69_018505	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
E0W69_018510	ENOG4105K46	50S ribosomal protein l27
E0W69_018525	ENOG41076PI	Short-chain dehydrogenase reductase Sdr
E0W69_018530	ENOG4108IUZ	ABC transporter
E0W69_018535	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
E0W69_018540	ENOG4105DZP	Membrane-associated zinc metalloprotease
E0W69_018565	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
E0W69_018570	ENOG4105IIU	Aminopeptidase
E0W69_018575	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
E0W69_018590	ENOG4106N3A	copper homeostasis protein cutc
E0W69_018595	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
E0W69_018610	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
E0W69_018625	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
E0W69_018630	ENOG4105C2M	dna polymerase I
E0W69_018635	ENOG4105CIY	formyltetrahydrofolate deformylase
E0W69_018655	ENOG41081UC	Inherit from COG: Competence protein
E0W69_018665	ENOG4108V06	Glutathione peroxidase
E0W69_018670	ENOG4105FA2	dna polymerase iii
E0W69_018675	ENOG4105MA4	psp1 domain protein
E0W69_018690	ENOG4108HRK	Histidine kinase
E0W69_018695	ENOG4105DY9	regulatoR
E0W69_018700	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
E0W69_018735	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
E0W69_018740	ENOG4105CUI	Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose (By similarity)
E0W69_018745	ENOG4105II7	pyrroline-5-carboxylate reductase
E0W69_018750	ENOG4105CJ1	ABC, transporter
E0W69_018775	ENOG4105C5X	domain protein
E0W69_018790	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
E0W69_018805	ENOG4105D64	Mechanosensitive ion channel
E0W69_018810	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
E0W69_018820	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
E0W69_018825	ENOG41090A1	ferritin
E0W69_018830	ENOG41083MR	nifu domain-containing protein
E0W69_018835	ENOG4107QXG	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
E0W69_018850	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
E0W69_018855	ENOG4105CBC	glutamate synthase
E0W69_018875	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
E0W69_018880	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
E0W69_018900	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_018935	ENOG4108V0P	LemA family
E0W69_018940	ENOG4105D3R	alkyl hydroperoxide reductase
E0W69_018945	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
E0W69_018960	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
E0W69_018965	ENOG4105C9K	Endothelin-converting enzyme 1
E0W69_018975	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
E0W69_018980	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
E0W69_018985	ENOG4105DU6	RNA polymerase
E0W69_018990	ENOG4105D17	glycoside hydrolase, family 3 domain protein
E0W69_019000	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
E0W69_019025	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
E0W69_019040	ENOG4105CEN	a g-specific adenine glycosylase
E0W69_019055	ENOG4105E6M	Sulphatase-modifying factor protein
E0W69_019100	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
E0W69_019135	ENOG4105DY9	regulatoR
E0W69_019140	ENOG4108HRK	Histidine kinase
E0W69_019145	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
E0W69_019155	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
E0W69_019170	ENOG4105CZ9	Domain of unknown function (DU1801)
E0W69_019190	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
E0W69_019195	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
E0W69_019200	ENOG4105CJQ	hydrolase, family 31
E0W69_019230	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_019240	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
E0W69_019265	ENOG41075SV	phosphoribosyltransferase
E0W69_019275	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
E0W69_019290	ENOG410756H	nucleotidyltransferase
E0W69_019335	ENOG4105E6M	Sulphatase-modifying factor protein
E0W69_019360	ENOG4105F32	YngK protein
E0W69_019390	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
E0W69_019420	ENOG4107SYZ	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
E0W69_019445	ENOG4108UJU	UPF0301 protein
E0W69_019480	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
E0W69_019485	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
E0W69_019495	ENOG4105HHA	aminodeoxychorismate lyase
E0W69_019520	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
E0W69_019530	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
E0W69_019540	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
E0W69_019560	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
E0W69_019565	ENOG4105D7A	ATP-binding protein
E0W69_019570	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
E0W69_019590	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
E0W69_019610	ENOG4105M8K	biopolymer transport protein
E0W69_019615	ENOG4109015	Biopolymer transport protein exbD tolR
E0W69_019620	ENOG4108UUM	single-stranded DNA-binding protein
E0W69_019625	ENOG4105C37	(CBS) domain
E0W69_019640	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
E0W69_019645	ENOG4108IUX	(ABC) transporter
E0W69_019650	ENOG4105RHA	ABC transporter, permease
E0W69_019660	ENOG4108RWI	nicotinamidase
E0W69_019665	ENOG4105C98	muts2 protein
E0W69_019685	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
E0W69_019700	ENOG4105C27	TonB-dependent Receptor Plug
E0W69_019710	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
E0W69_019715	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
E0W69_019720	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
E0W69_019725	ENOG4107V8H	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
E0W69_019760	ENOG4105CN1	protease
E0W69_019795	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
E0W69_019810	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
E0W69_019815	ENOG4105VG0	50S ribosomal protein l34
E0W69_019835	ENOG4105E2X	shikimate dehydrogenase
E0W69_019840	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
E0W69_019850	ENOG4105CM2	brancheD-chain amino acid aminotransferase
E0W69_019855	ENOG4107ZT5	Thiol disulfide interchange protein
E0W69_019860	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
E0W69_019865	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
E0W69_019870	ENOG4105EGY	DNA internalization-related competence protein ComEC Rec2
E0W69_019875	ENOG4105DC1	bifunctional purine biosynthesis protein purh
E0W69_019895	ENOG4105E3B	Multicopper oxidase
E0W69_019920	ENOG4105D6A	Electron transport complex
E0W69_019950	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
E0W69_019955	ENOG4105CXT	aspartate transcarbamylase
E0W69_019960	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
E0W69_019970	ENOG4105C5I	Dehydrogenase
E0W69_019980	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
E0W69_020015	ENOG410635A	Membrane
E0W69_020020	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
E0W69_020035	ENOG4105C11	sulfate adenylyltransferase), subunit 2
E0W69_020050	ENOG4108HRK	Histidine kinase
E0W69_020055	ENOG4105DY9	regulatoR
E0W69_020100	ENOG4105KJF	protein tyrosine phosphatase
E0W69_020115	ENOG4107RAQ	aminopeptidase
E0W69_020135	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
E0W69_020170	ENOG4105F27	Major Facilitator
E0W69_020180	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
E0W69_020185	ENOG4107QWK	SAICAR synthetase
E0W69_020190	ENOG4107YM1	mraZ protein
E0W69_020195	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
E0W69_020205	ENOG4105CJN	penicillin-binding protein
E0W69_020210	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
E0W69_020215	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
E0W69_020220	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
E0W69_020240	ENOG4108C33	Resolvase
E0W69_020280	ENOG4107QJE	Chromosome Partitioning Protein