locus-tag	class	description
D6B99_00035	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
D6B99_00040	ENOG4105C8S	subunit m
D6B99_00045	ENOG4105D65	subunit l
D6B99_00050	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
D6B99_00060	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
D6B99_00065	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
D6B99_00080	ENOG4105GKE	subunit e
D6B99_00095	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
D6B99_00105	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
D6B99_00110	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
D6B99_00115	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
D6B99_00120	ENOG4105C8N	cysteinyl-tRNA synthetase
D6B99_00140	ENOG4105C59	p-type ATPase
D6B99_00150	ENOG4105DCF	alanine dehydrogenase
D6B99_00180	ENOG4105CJN	penicillin-binding protein
D6B99_00185	ENOG4105CNI	cell division protein FtsW
D6B99_00190	ENOG4105D7N	magnesium and cobalt transport protein CorA
D6B99_00195	ENOG4105EJQ	L-serine dehydratase
D6B99_00210	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
D6B99_00215	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
D6B99_00225	ENOG4105E0X	reductase
D6B99_00240	ENOG4105CEU	Arginine dihydrolase
D6B99_00250	ENOG4105CE1	Ferrous iron transport protein b
D6B99_00295	ENOG4105DVT	helicase
D6B99_00300	ENOG4105C0B	DNA polymerase III (alpha subunit)
D6B99_00305	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
D6B99_00330	ENOG4105F8V	Hydrolase, tatD family
D6B99_00335	ENOG4107UGT	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
D6B99_00340	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
D6B99_00355	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
D6B99_00360	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
D6B99_00365	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
D6B99_00380	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D6B99_00395	ENOG4105DY9	regulatoR
D6B99_00400	ENOG4108HRK	Histidine kinase
D6B99_00405	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
D6B99_00410	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
D6B99_00425	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
D6B99_00445	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
D6B99_00450	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
D6B99_00455	ENOG4105BZA	Phosphoglycerate kinase
D6B99_00460	ENOG4108Z9K	Osmotically inducible protein
D6B99_00475	ENOG4107TPS	domain protein
D6B99_00485	ENOG41072GX	Peptidase M22 Glycoprotease
D6B99_00490	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
D6B99_00500	ENOG4107SFQ	iron-sulfur binding
D6B99_00525	ENOG4105Z4T	Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity)
D6B99_00530	ENOG4105BZ9	Cytochrome C oxidase, subunit I
D6B99_00535	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
D6B99_00540	ENOG4105CCU	oxidase (Subunit III)
D6B99_00545	ENOG4105CCU	oxidase (Subunit III)
D6B99_00560	ENOG4108SJC	Membrane
D6B99_00570	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_00585	ENOG4108HRK	Histidine kinase
D6B99_00590	ENOG4108NEV	two component transcriptional regulator, LytTR family
D6B99_00595	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
D6B99_00600	ENOG4107QWK	SAICAR synthetase
D6B99_00605	ENOG4108Z0R	Transferase
D6B99_00610	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
D6B99_00630	ENOG4105DA4	cytochrome c-type biogenesis protein
D6B99_00640	ENOG4105EXU	Membrane
D6B99_00645	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
D6B99_00650	ENOG4105CP2	von willebrand factor, type a
D6B99_00670	ENOG4108VVK	transcriptional Regulator, AsnC
D6B99_00700	ENOG4105R48	this blockage is overcome by subsequent expression of antitoxin HigA. Overexpression causes cleavage of a number of mRNAs in a translation-dependent fashion, suggesting this is an mRNA interferase
D6B99_00710	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
D6B99_00715	ENOG4105CB2	alcohol dehydrogenase
D6B99_00720	ENOG4105CSM	endonuclease III
D6B99_00740	ENOG4105HHA	aminodeoxychorismate lyase
D6B99_00760	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D6B99_00765	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D6B99_00770	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
D6B99_00785	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
D6B99_00790	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
D6B99_00795	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D6B99_00805	ENOG4105VFU	Rna-binding protein
D6B99_00810	ENOG4105E2D	ec 3.2.1.52
D6B99_00815	ENOG4105DFA	alanine racemase domain protein
D6B99_00825	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
D6B99_00830	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
D6B99_00845	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
D6B99_00905	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
D6B99_00910	ENOG4105D7A	ATP-binding protein
D6B99_00920	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
D6B99_00945	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
D6B99_00950	ENOG4105D05	Receptor
D6B99_00955	ENOG4105CUR	5'-nucleotidase, lipoprotein e(p4) family
D6B99_00960	ENOG4105II7	pyrroline-5-carboxylate reductase
D6B99_00965	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
D6B99_00970	ENOG4107RAQ	aminopeptidase
D6B99_00985	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
D6B99_00995	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
D6B99_01015	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
D6B99_01045	ENOG41077A9	carbonic anhydrase
D6B99_01050	ENOG4105CHR	reductase
D6B99_01085	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
D6B99_01090	ENOG4105VEJ	Heat shock protein
D6B99_01105	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
D6B99_01115	ENOG4105CPN	adenine deaminase
D6B99_01170	ENOG4105F2F	Xylan 1,4-beta-xylosidase (EC 3.2.1.37)
D6B99_01180	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
D6B99_01190	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
D6B99_01220	ENOG4105EX0	alpha-galactosidase
D6B99_01225	ENOG4105D28	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
D6B99_01235	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
D6B99_01240	ENOG4105C1G	acyl-Coa dehydrogenase
D6B99_01265	ENOG4105E0M	Sulfatase
D6B99_01445	ENOG4105BZ1	(ABC) transporter
D6B99_01450	ENOG4105F0N	pyrophosphate phospho-hydrolase
D6B99_01460	ENOG4105C0D	helicase
D6B99_01465	ENOG4105CH7	arginosuccinase
D6B99_01470	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
D6B99_01475	ENOG4105CWC	Acetylornithine deacetylase
D6B99_01480	ENOG4107T6X	nag kinase
D6B99_01490	ENOG4107REN	Carbamoyltransferase
D6B99_01500	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
D6B99_01505	ENOG4105CDH	Citrulline--aspartate ligase
D6B99_01520	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
D6B99_01535	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
D6B99_01540	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D6B99_01560	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
D6B99_01575	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
D6B99_01580	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
D6B99_01585	ENOG4105CSA	Coproporphyrinogen iii oxidase
D6B99_01590	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
D6B99_01595	ENOG4105CDU	Replicative dna helicase
D6B99_01595	ENOG4105CDU	Replicative dna helicase
D6B99_01620	ENOG4105DKQ	ROK family
D6B99_01625	ENOG4105EDR	glucose galactose transporter
D6B99_01630	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
D6B99_01635	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
D6B99_01640	ENOG4105C8F	Beta-lactamase domain protein
D6B99_01650	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
D6B99_01660	ENOG4105CBG	Sulfatase
D6B99_01675	ENOG4105F32	YngK protein
D6B99_01690	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
D6B99_01695	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
D6B99_01700	ENOG41061MV	Arylsulfatase
D6B99_01705	ENOG4105ENH	Sulfatase
D6B99_01710	ENOG4105E39	Enoyl-CoA hydratase
D6B99_01715	ENOG4105CR4	methylisocitrate lyase
D6B99_01720	ENOG4105BZN	citrate synthase
D6B99_01725	ENOG4105DXD	2-methylcitrate dehydratase
D6B99_01735	ENOG4105C1G	acyl-Coa dehydrogenase
D6B99_01740	ENOG4105D7V	transposase
D6B99_01760	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_01770	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_01805	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
D6B99_01810	ENOG4108MYR	Secreted protein
D6B99_01875	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
D6B99_01885	ENOG4105C5E	polysaccharide biosynthesis protein
D6B99_01895	ENOG4105KME	endoribonuclease L-psp
D6B99_01945	ENOG4107QX3	carboxylase
D6B99_01955	ENOG4105EIP	mannose-6-phosphate isomerase
D6B99_01965	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D6B99_01970	ENOG4105FQP	Beta-lactamase
D6B99_01975	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
D6B99_01980	ENOG4105CP7	Triose-phosphate isomerase
D6B99_01985	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
D6B99_02010	ENOG4105C7Z	Conserved Protein
D6B99_02015	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
D6B99_02020	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
D6B99_02025	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
D6B99_02030	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
D6B99_02045	ENOG4107RJC	Iron-containing alcohol dehydrogenase
D6B99_02055	ENOG4105NAE	bifunctional deaminase-reductase domain protein
D6B99_02085	ENOG4105W4W	Transcriptional regulator
D6B99_02100	ENOG4105BZ1	(ABC) transporter
D6B99_02105	ENOG4105BZ1	(ABC) transporter
D6B99_02115	ENOG4105C5Q	Transcriptional regulator
D6B99_02120	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
D6B99_02130	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
D6B99_02145	ENOG4105CNT	hydrolase family 2
D6B99_02155	ENOG4106KXD	ATP-dependent carboxylate-amine ligase (By similarity)
D6B99_02175	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D6B99_02180	ENOG4108RYK	Nad-dependent epimerase dehydratase
D6B99_02205	ENOG4105CEN	a g-specific adenine glycosylase
D6B99_02215	ENOG4108IUW	ABC transporter
D6B99_02250	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
D6B99_02255	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
D6B99_02265	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
D6B99_02270	ENOG4105DTN	riboflavin biosynthesis protein ribF
D6B99_02275	ENOG4105BZ1	(ABC) transporter
D6B99_02280	ENOG4105H4N	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
D6B99_02285	ENOG4105D60	lipoprotein releasing system transmembrane protein
D6B99_02320	ENOG4105CD3	dihydroorotase
D6B99_02325	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
D6B99_02335	ENOG4105KDC	50s ribosomal protein l28
D6B99_02340	ENOG41083ND	50S ribosomal protein L33
D6B99_02350	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
D6B99_02370	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
D6B99_02395	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
D6B99_02405	ENOG4105E98	transcriptional regulator DeoR family
D6B99_02410	ENOG4108IXY	short-chain dehydrogenase reductase
D6B99_02415	ENOG4105T16	Transcriptional regulator (AraC family)
D6B99_02460	ENOG4105C2I	pirin domain protein
D6B99_02465	ENOG4105CJH	Alcohol dehydrogenase zinc-binding domain protein
D6B99_02475	ENOG4105EMU	Dehydrogenase
D6B99_02490	ENOG4105EQ0	Major Facilitator superfamily
D6B99_02495	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
D6B99_02500	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
D6B99_02510	ENOG4105C5X	domain protein
D6B99_02520	ENOG41090X3	Peptidyl-prolyl cis-trans isomerase
D6B99_02525	ENOG4105C34	Pseudouridine synthase
D6B99_02530	ENOG4105D05	Receptor
D6B99_02550	ENOG4107QTF	adenylosuccinate lyase
D6B99_02570	ENOG4108UKZ	OsmC family
D6B99_02575	ENOG4105C28	cystathionine
D6B99_02590	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
D6B99_02600	ENOG4105C5H	ABC transporter
D6B99_02610	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
D6B99_02620	ENOG4105FCI	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate (By similarity)
D6B99_02630	ENOG4105C6K	Malic enzyme
D6B99_02640	ENOG4105E4T	pyridine nucleotide-disulfide oxidoreductase
D6B99_02645	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
D6B99_02660	ENOG4105C1J	atp-dependent rna helicase
D6B99_02675	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
D6B99_02730	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
D6B99_02740	ENOG4105RA3	Binds directly to 16S ribosomal RNA (By similarity)
D6B99_02750	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
D6B99_02755	ENOG4105C7S	Dehydrogenase
D6B99_02770	ENOG4107R6T	Involved in the transcription termination process (By similarity)
D6B99_02780	ENOG4105VIE	preprotein translocase, subunit YajC
D6B99_02805	ENOG4105DCG	PHP domain protein
D6B99_02810	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
D6B99_02820	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
D6B99_02835	ENOG4105E33	succinate dehydrogenase
D6B99_02845	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D6B99_02850	ENOG41083X6	30S ribosomal protein S21
D6B99_02855	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
D6B99_02860	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
D6B99_02880	ENOG4108V1T	peptidylprolyl cis-trans isomerase
D6B99_02900	ENOG4105C3D	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
D6B99_02915	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D6B99_02925	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
D6B99_02940	ENOG4108Z5K	methylglyoxal synthase
D6B99_02965	ENOG4105CHU	acetyl-coa acetyltransferase
D6B99_02970	ENOG4105EGS	Mechanosensitive ion channel
D6B99_02990	ENOG41074B2	UPF0747 protein
D6B99_02995	ENOG4105CBM	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 (By similarity)
D6B99_03030	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
D6B99_03055	ENOG4105CPP	Dehydrogenase, E1 component
D6B99_03060	ENOG4105EMU	Dehydrogenase
D6B99_03065	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
D6B99_03070	ENOG4105CNT	hydrolase family 2
D6B99_03080	ENOG4105ETE	Transcriptional regulator (LacI family
D6B99_03085	ENOG4105D2H	Uronic isomerase
D6B99_03095	ENOG4105XEP	YhcH YjgK YiaL family protein
D6B99_03100	ENOG4108UHU	Aldolase
D6B99_03115	ENOG4105DMW	Dehydrogenase reductase
D6B99_03120	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
D6B99_03125	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
D6B99_03135	ENOG4105DJV	ribulose-phosphate 3-epimerase
D6B99_03140	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
D6B99_03155	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
D6B99_03160	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
D6B99_03165	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
D6B99_03205	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
D6B99_03210	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
D6B99_03215	ENOG4107XQK	5-formyltetrahydrofolate cyclo-ligase
D6B99_03230	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
D6B99_03235	ENOG4105KUZ	arsenate reductase
D6B99_03245	ENOG4108Z03	MAF-like protein
D6B99_03270	ENOG4105BZ1	(ABC) transporter
D6B99_03285	ENOG4108VPT	UPF0234 protein
D6B99_03305	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
D6B99_03315	ENOG4105QPS	Monooxygenase
D6B99_03320	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
D6B99_03330	ENOG4105ERH	Fumarylacetoacetate hydrolase
D6B99_03335	ENOG4105EW6	flavin reductase domain protein, FMN-binding
D6B99_03345	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
D6B99_03355	ENOG4105CRK	lysyL-tRNA synthetase
D6B99_03370	ENOG4108HRK	Histidine kinase
D6B99_03375	ENOG4108NEV	two component transcriptional regulator, LytTR family
D6B99_03395	ENOG4108RMU	ferritin dps family protein
D6B99_03410	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D6B99_03415	ENOG4105CHM	Aminotransferase
D6B99_03425	ENOG4108DBC	nitroreductase
D6B99_03445	ENOG4108BHK	preprotein translocase subunit SecE
D6B99_03485	ENOG41082J7	Rhodanese domain protein
D6B99_03490	ENOG4105D9P	serine threonine protein kinase
D6B99_03495	ENOG4105CPF	Cell wall formation (By similarity)
D6B99_03500	ENOG4105CGK	Exodeoxyribonuclease III
D6B99_03510	ENOG4105K70	DNA-binding protein
D6B99_03520	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
D6B99_03525	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
D6B99_03535	ENOG4107RGW	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
D6B99_03550	ENOG4105C3G	gtp-binding protein
D6B99_03585	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
D6B99_03590	ENOG4105CMD	Transcriptional regulator, GntR family
D6B99_03605	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
D6B99_03610	ENOG4105C9B	Cysteine desulfurase
D6B99_03620	ENOG4105C3K	feS assembly ATPase SufC
D6B99_03630	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
D6B99_03650	ENOG4105CGZ	zinc metallopeptidase
D6B99_03655	ENOG4105EMU	Dehydrogenase
D6B99_03670	ENOG4105CTQ	phosphohexokinase
D6B99_03685	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
D6B99_03690	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
D6B99_03695	ENOG4108UGJ	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity (By similarity)
D6B99_03700	ENOG4105BZ1	(ABC) transporter
D6B99_03705	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
D6B99_03710	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
D6B99_03715	ENOG4106HK8	GPR1 FUN34 yaaH family protein
D6B99_03725	ENOG4105C5H	ABC transporter
D6B99_03735	ENOG4107RAJ	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
D6B99_03740	ENOG4107YB6	acetyltransferase, (GNAT) family
D6B99_03770	ENOG4105DUM	transcriptional regulator, lysR family
D6B99_03775	ENOG4105HMI	Membrane
D6B99_03785	ENOG4105C84	Histidine ammonia-lyase
D6B99_03795	ENOG4105CI2	imidazolone-5-propionate hydrolase
D6B99_03800	ENOG41088SP	formiminoglutamate hydrolase
D6B99_03805	ENOG4105C9Q	fumarate hydratase class II
D6B99_03815	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
D6B99_03820	ENOG4107T7F	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
D6B99_03830	ENOG4105C26	Dehydrogenase
D6B99_03845	ENOG4107S9R	deoxycytidine triphosphate deaminase
D6B99_03860	ENOG4105KZX	Pterin carbinolamine dehydratase
D6B99_03875	ENOG4105WMR	Protein CrcB homolog
D6B99_03880	ENOG4107R4J	Chloride channel
D6B99_03915	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_03920	ENOG4108MYR	Secreted protein
D6B99_03925	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
D6B99_03945	ENOG4105EMN	RNA polymerase sigma factor
D6B99_03955	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
D6B99_03970	ENOG4105C7B	Threonine dehydratase
D6B99_03985	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
D6B99_03990	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
D6B99_04005	ENOG4108ZP8	Acetolactate synthase small subunit
D6B99_04010	ENOG4105C7K	acetolactate synthase
D6B99_04020	ENOG41089UC	methyltransferase, type 11
D6B99_04025	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
D6B99_04030	ENOG4105DKW	ABC transporter
D6B99_04035	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
D6B99_04040	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D6B99_04045	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
D6B99_04050	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
D6B99_04055	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
D6B99_04065	ENOG4105CBC	glutamate synthase
D6B99_04070	ENOG4105C7K	acetolactate synthase
D6B99_04075	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
D6B99_04085	ENOG4105CFH	Aspartokinase
D6B99_04090	ENOG4105CJ1	ABC, transporter
D6B99_04100	ENOG4108YZ4	nudix hydrolase
D6B99_04110	ENOG4107R7I	amino acid
D6B99_04120	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
D6B99_04125	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D6B99_04140	ENOG4105DJ1	Phosphoenolpyruvate Carboxylase
D6B99_04145	ENOG4108JQ1	Dehydrogenase
D6B99_04155	ENOG4105D7V	transposase
D6B99_04165	ENOG4105C9X	ppx gppa phosphatase
D6B99_04170	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
D6B99_04175	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
D6B99_04180	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
D6B99_04185	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
D6B99_04200	ENOG4107QXV	Phosphate transporter
D6B99_04205	ENOG4105CMR	udp-glucose 4-epimerase
D6B99_04210	ENOG4108IUS	Transketolase
D6B99_04215	ENOG4105EMN	RNA polymerase sigma factor
D6B99_04235	ENOG4108RWN	rrna methyltransferase
D6B99_04245	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
D6B99_04250	ENOG4108IDZ	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
D6B99_04255	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
D6B99_04260	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
D6B99_04270	ENOG4108SAY	Involved in DNA repair and RecF pathway recombination (By similarity)
D6B99_04295	ENOG4107SCJ	type I restriction enzyme EcoKI subunit R
D6B99_04300	ENOG4105CVR	type I restriction-modification system
D6B99_04345	ENOG4105CHR	reductase
D6B99_04355	ENOG4105CFH	Aspartokinase
D6B99_04365	ENOG4105CJW	magnesium transporter
D6B99_04385	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
D6B99_04390	ENOG4105C8U	phosphate abc transporter
D6B99_04395	ENOG4105E2Z	phosphate ABC transporter (Permease
D6B99_04400	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
D6B99_04405	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
D6B99_04415	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
D6B99_04420	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
D6B99_04430	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
D6B99_04450	ENOG4105D7V	transposase
D6B99_04465	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D6B99_04475	ENOG4107R3N	Filamentation induced by cAMP protein fic
D6B99_04500	ENOG4105D5U	fad dependent oxidoreductase
D6B99_04520	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
D6B99_04525	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
D6B99_04530	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
D6B99_04535	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
D6B99_04545	ENOG41067S9	phage shock protein C, PspC
D6B99_04550	ENOG4105K7K	Transcriptional regulator
D6B99_04560	ENOG4105CUT	histidyl-tRNA synthetase
D6B99_04570	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
D6B99_04575	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
D6B99_04585	ENOG4107R0V	Pyruvate dehydrogenase
D6B99_04595	ENOG4107T8J	thymidine kinase
D6B99_04610	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
D6B99_04635	ENOG4105W5Q	DNA repair protein (RadC
D6B99_04640	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
D6B99_04645	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
D6B99_04660	ENOG4105DNX	Dna topoisomerase iv (Subunit b)
D6B99_04670	ENOG4105DF5	DNA topoisomerase IV, subunit A
D6B99_04675	ENOG4105CDV	Ompa motb domain protein
D6B99_04680	ENOG41080B9	Binds together with S18 to 16S ribosomal RNA (By similarity)
D6B99_04685	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
D6B99_04690	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
D6B99_04700	ENOG4105CNM	Receptor
D6B99_04715	ENOG4105CN1	protease
D6B99_04730	ENOG4105CNU	cell division protein FtsK
D6B99_04740	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
D6B99_04745	ENOG4108HRK	Histidine kinase
D6B99_04750	ENOG4105DY9	regulatoR
D6B99_04785	ENOG4105EKQ	RNA-directed DNA polymerase
D6B99_04795	ENOG4105CHM	Aminotransferase
D6B99_04805	ENOG4105C1J	atp-dependent rna helicase
D6B99_04810	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
D6B99_04815	ENOG4105D49	3-dehydroquinate synthase
D6B99_04820	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
D6B99_04825	ENOG4105EIE	fructose-bisphosphate aldolase
D6B99_04835	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
D6B99_04840	ENOG4107Y2X	deaminase
D6B99_04845	ENOG4105C9K	Endothelin-converting enzyme 1
D6B99_04860	ENOG4105CUB	amino acid
D6B99_04865	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
D6B99_04870	ENOG4107R0I	Cell wall formation (By similarity)
D6B99_04880	ENOG4105CEP	NADH dehydrogenase
D6B99_04905	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
D6B99_04910	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
D6B99_04920	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
D6B99_04930	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
D6B99_04950	ENOG4105DFS	Conserved Protein
D6B99_04960	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
D6B99_04970	ENOG4105TCD	Broad-specificity glycosaminoglycan lyase (By similarity)
D6B99_04975	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
D6B99_04990	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
D6B99_05000	ENOG4108IYU	L-aspartate oxidase
D6B99_05005	ENOG4105CUB	amino acid
D6B99_05010	ENOG4105CK2	sodium dicarboxylate symporter
D6B99_05015	ENOG4105DQR	SNARE associated Golgi
D6B99_05020	ENOG4105C31	Tryptophanyl-tRNA synthetase
D6B99_05025	ENOG4105ZMH	deoxynucleoside kinase
D6B99_05035	ENOG4105DTQ	mandelate racemase muconate lactonizing
D6B99_05040	ENOG4105ETE	Transcriptional regulator (LacI family
D6B99_05050	ENOG4105CHR	reductase
D6B99_05055	ENOG4105D50	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate (By similarity)
D6B99_05070	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
D6B99_05095	ENOG4107QN2	dihydrolipoyl dehydrogenase
D6B99_05100	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
D6B99_05105	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
D6B99_05135	ENOG4105W4W	Transcriptional regulator
D6B99_05175	ENOG4106CKV	Pap2 superfamily protein
D6B99_05200	ENOG4105GR3	Histidine kinase
D6B99_05205	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
D6B99_05225	ENOG4105C22	threonyL-tRNA synthetase
D6B99_05230	ENOG4108V1J	Has antioxidant activity. Could remove peroxides or H(2)O(2) (By similarity)
D6B99_05240	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
D6B99_05255	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
D6B99_05265	ENOG4108N9J	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
D6B99_05270	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
D6B99_05275	ENOG41081WG	50s ribosomal protein l31
D6B99_05285	ENOG4105CW7	secretion protein, HlyD family
D6B99_05300	ENOG4105CMQ	Chloride channel
D6B99_05305	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
D6B99_05310	ENOG4105CPC	Aldo Keto reductase
D6B99_05315	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
D6B99_05320	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
D6B99_05330	ENOG4107QWR	cellulase (EC 3.2.1.4)
D6B99_05335	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_05340	ENOG4105TT1	Ragb susd domain-containing protein
D6B99_05350	ENOG4105D3P	Mannan endo-1,4-beta-mannosidase
D6B99_05365	ENOG4105HY2	Glycosidase related protein
D6B99_05370	ENOG4105DFY	n-acylglucosamine 2-epimerase
D6B99_05380	ENOG4105EX0	alpha-galactosidase
D6B99_05400	ENOG4105EBR	Carboxylesterase
D6B99_05410	ENOG4105CUK	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
D6B99_05420	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
D6B99_05425	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_05450	ENOG4105CNT	hydrolase family 2
D6B99_05455	ENOG4105D3R	alkyl hydroperoxide reductase
D6B99_05460	ENOG4108KPZ	tonB-dependent Receptor
D6B99_05470	ENOG4105KPV	Transcriptional regulator
D6B99_05475	ENOG4105EUH	cytochrome C oxidase, cbb3-type, subunit i
D6B99_05480	ENOG41067HZ	cytochrome C, class I
D6B99_05495	ENOG4105VIG	Sec-independent protein translocase protein TatC
D6B99_05505	ENOG4105FJH	Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions (By similarity)
D6B99_05510	ENOG4105K78	MarR family Transcriptional regulator
D6B99_05520	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
D6B99_05525	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
D6B99_05530	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D6B99_05535	ENOG4105C9M	aspartyl-trna synthetase
D6B99_05540	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
D6B99_05545	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
D6B99_05550	ENOG4105CIH	Imidazole acetol-phosphate transaminase
D6B99_05555	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
D6B99_05560	ENOG4105CFG	Acts as a chaperone (By similarity)
D6B99_05575	ENOG4105EMU	Dehydrogenase
D6B99_05580	ENOG4105DHJ	ABC, transporter
D6B99_05585	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
D6B99_05595	ENOG4108Z7F	N-acetyltransferase
D6B99_05600	ENOG4105EQ6	Hydrolyzes dipeptides containing N-terminal aspartate residues. May play a role in allowing the cell to use peptide aspartate to spare carbon otherwise required for the synthesis of the aspartate family of amino acids (By similarity)
D6B99_05610	ENOG4105C9A	Phoh family
D6B99_05620	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
D6B99_05635	ENOG410624X	efflux transporter, rnd family, mfp subunit
D6B99_05665	ENOG4105HCZ	
D6B99_05670	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
D6B99_05700	ENOG4107R3N	Filamentation induced by cAMP protein fic
D6B99_05710	ENOG4105CPC	Aldo Keto reductase
D6B99_05720	ENOG4107TT5	NLP P60 protein
D6B99_05735	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
D6B99_05740	ENOG4105C08	Histidine kinase
D6B99_05745	ENOG4105EEX	Two component transcriptional regulator (Winged helix family
D6B99_05750	ENOG4105DFH	Transport of potassium into the cell (By similarity)
D6B99_05760	ENOG4107QR9	Iron-sulfur cluster binding protein
D6B99_05785	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
D6B99_05790	ENOG4107RIV	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
D6B99_05795	ENOG41062IR	nudix hydrolase
D6B99_05805	ENOG4105XA0	heptosyltransferase ii
D6B99_05815	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
D6B99_05825	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
D6B99_05835	ENOG4108JQC	penicillin-binding protein 1A
D6B99_05870	ENOG4105C34	Pseudouridine synthase
D6B99_05875	ENOG4105FE9	pseudouridine synthase
D6B99_05880	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
D6B99_05890	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
D6B99_05905	ENOG4105C25	Primosomal protein n'
D6B99_05910	ENOG4105VMP	Transcriptional regulator
D6B99_05945	ENOG4105E2D	ec 3.2.1.52
D6B99_05965	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
D6B99_05985	ENOG4107QJZ	Glycosyl transferase, family 2
D6B99_06020	ENOG4105CYW	agmatinase
D6B99_06040	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
D6B99_06045	ENOG4105EXW	epimerase dehydratase
D6B99_06065	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
D6B99_06070	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
D6B99_06075	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
D6B99_06080	ENOG4107S2Z	UPF0761 membrane protein
D6B99_06085	ENOG4105DVT	helicase
D6B99_06095	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
D6B99_06105	ENOG4108V1T	peptidylprolyl cis-trans isomerase
D6B99_06110	ENOG4105EYW	Ion transport protein
D6B99_06120	ENOG4105CN1	protease
D6B99_06130	ENOG4108I0Z	Aconitate hydratase
D6B99_06140	ENOG4105C26	Dehydrogenase
D6B99_06175	ENOG4107R76	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity)
D6B99_06180	ENOG4105C03	ribonuclease
D6B99_06190	ENOG4105K70	DNA-binding protein
D6B99_06230	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
D6B99_06235	ENOG4105MA4	psp1 domain protein
D6B99_06240	ENOG4105FA2	dna polymerase iii
D6B99_06250	ENOG4108V06	Glutathione peroxidase
D6B99_06255	ENOG4105C2M	dna polymerase I
D6B99_06260	ENOG41068WN	
D6B99_06275	ENOG4108S4H	thioesterase Superfamily protein
D6B99_06280	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
D6B99_06285	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D6B99_06295	ENOG4105C2N	RNA methyltransferase TrmH family group 3
D6B99_06305	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
D6B99_06310	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
D6B99_06320	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
D6B99_06330	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
D6B99_06335	ENOG4105DK0	Indole-3-glycerol phosphate synthase
D6B99_06345	ENOG4107RI6	Anthranilate phosphoribosyltransferase
D6B99_06355	ENOG4105DDQ	anthranilate synthase
D6B99_06360	ENOG4105CRQ	synthase (Component I)
D6B99_06370	ENOG4107ZXU	DSBA oxidoreductase
D6B99_06375	ENOG4105FFC	UPF0187 protein
D6B99_06400	ENOG4105K5D	4fe-4S ferredoxin iroN-sulfur binding
D6B99_06415	ENOG4105EUB	pirin domain protein
D6B99_06420	ENOG4105EUB	pirin domain protein
D6B99_06430	ENOG4105C9K	Endothelin-converting enzyme 1
D6B99_06435	ENOG4108ZJ4	polysaccharide deacetylase
D6B99_06445	ENOG4105C3M	thioredoxin reductase
D6B99_06480	ENOG4105F2F	Xylan 1,4-beta-xylosidase (EC 3.2.1.37)
D6B99_06485	ENOG4108K2F	hydrolase Family 5
D6B99_06500	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_06520	ENOG4108K2F	hydrolase Family 5
D6B99_06525	ENOG4105CNT	hydrolase family 2
D6B99_06530	ENOG4105ETE	Transcriptional regulator (LacI family
D6B99_06545	ENOG4107TDE	lipolytic protein G-D-S-L family
D6B99_06570	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_06580	ENOG4107XII	Glycosyl Hydrolase Family 88
D6B99_06595	ENOG4105E4I	Glycoside hydrolase family 28
D6B99_06630	ENOG4108MHR	Repressor involved in choline regulation of the bet genes (By similarity)
D6B99_06670	ENOG4105D7V	transposase
D6B99_06705	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_06745	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_06765	ENOG41073TP	transcriptional regulator
D6B99_06770	ENOG4105C0H	protease
D6B99_06795	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_06815	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
D6B99_06820	ENOG4105CBZ	Short-chain dehydrogenase reductase Sdr
D6B99_06830	ENOG4105KVH	Transcriptional regulator
D6B99_06840	ENOG4105D29	Helix-turn-helix type 11 domain protein
D6B99_06845	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D6B99_06855	ENOG4105C8E	extradiol ring-cleavage dioxygenase class IIi protein subunit b
D6B99_06860	ENOG4108YYC	ycei family
D6B99_06865	ENOG4105KVH	Transcriptional regulator
D6B99_06880	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D6B99_06885	ENOG4108IG5	Transcriptional regulator
D6B99_06890	ENOG4105EGI	Transcriptional regulator
D6B99_06900	ENOG4105C5H	ABC transporter
D6B99_06930	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D6B99_06950	ENOG4105VN1	Heat shock protein
D6B99_06955	ENOG4105C0B	DNA polymerase III (alpha subunit)
D6B99_07000	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D6B99_07040	ENOG4105BZU	Histidine kinase
D6B99_07080	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D6B99_07115	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_07155	ENOG4105F1Y	L-lysine 6-monooxygenase (NADPH)
D6B99_07330	ENOG4107RAN	Peptidase, M16
D6B99_07345	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
D6B99_07350	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
D6B99_07360	ENOG4105DA5	(ABC) transporter
D6B99_07370	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_07400	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_07450	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
D6B99_07465	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
D6B99_07470	ENOG4107RAN	Peptidase, M16
D6B99_07490	ENOG4105C6T	cysteine synthase
D6B99_07495	ENOG4108ZRZ	Transcriptional regulator (AsnC family)
D6B99_07505	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D6B99_07510	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D6B99_07520	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_07550	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_07600	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
D6B99_07620	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
D6B99_07645	ENOG4105D1H	recombination factor protein RarA
D6B99_07650	ENOG4105EX0	alpha-galactosidase
D6B99_07665	ENOG4105CWX	Alpha-1,2-mannosidase
D6B99_07670	ENOG4105CWX	Alpha-1,2-mannosidase
D6B99_07700	ENOG4107UWA	esterase
D6B99_07710	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_07750	ENOG4105EDR	glucose galactose transporter
D6B99_07800	ENOG4105CNT	hydrolase family 2
D6B99_07805	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
D6B99_07825	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
D6B99_07835	ENOG4106HB6	Alpha beta hydrolase
D6B99_07840	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
D6B99_07845	ENOG4105D8V	Glucose sorbosone dehydrogenase
D6B99_07855	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
D6B99_07865	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
D6B99_07870	ENOG4105IIU	Aminopeptidase
D6B99_07890	ENOG4105D7V	transposase
D6B99_07925	ENOG4105NAE	bifunctional deaminase-reductase domain protein
D6B99_07935	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
D6B99_07940	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
D6B99_07960	ENOG4105DYS	nad(p)h dehydrogenase (quinone)
D6B99_08030	ENOG4107R55	ethanolamine transporter
D6B99_08035	ENOG4108ZX5	transcriptional regulator
D6B99_08055	ENOG4107R91	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
D6B99_08060	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
D6B99_08065	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
D6B99_08075	ENOG4105CEV	competence damage-inducible protein
D6B99_08080	ENOG4107RGD	Major Facilitator superfamily
D6B99_08085	ENOG4105C8Y	Acetylornithine aminotransferase
D6B99_08090	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
D6B99_08115	ENOG4107QP7	CoA-transferase subunit A
D6B99_08130	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
D6B99_08135	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
D6B99_08140	ENOG4108UK1	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant (By similarity)
D6B99_08145	ENOG4108V1T	peptidylprolyl cis-trans isomerase
D6B99_08150	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
D6B99_08155	ENOG4105CZ9	Domain of unknown function (DU1801)
D6B99_08160	ENOG4105CB1	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate (By similarity)
D6B99_08180	ENOG4105BZ1	(ABC) transporter
D6B99_08185	ENOG4108JQ6	ABC transporter
D6B99_08200	ENOG4105E6M	Sulphatase-modifying factor protein
D6B99_08205	ENOG4105C5H	ABC transporter
D6B99_08215	ENOG4105CBG	Sulfatase
D6B99_08235	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_08275	ENOG4105VYA	Uncharacterized conserved protein (DUF2132)
D6B99_08285	ENOG4105VXP	Protein of unknown function DUF86
D6B99_08310	ENOG4105EM2	membrane
D6B99_08315	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
D6B99_08325	ENOG4108UUM	single-stranded DNA-binding protein
D6B99_08330	ENOG4105K64	Glycosyl transferase, family 2
D6B99_08345	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
D6B99_08355	ENOG4108N5B	2-phosphosulfolactate phosphatase
D6B99_08370	ENOG4105US7	Histidine kinase
D6B99_08385	ENOG4105VDW	Csbd family
D6B99_08395	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
D6B99_08410	ENOG4105CAC	Catalyzes the conversion of L-arabinose to L-ribulose (By similarity)
D6B99_08420	ENOG4105EF1	ribulokinase
D6B99_08425	ENOG4105EMN	RNA polymerase sigma factor
D6B99_08435	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_08465	ENOG4107YRA	Uptake of L-rhamnose across the boundary membrane with the concomitant transport of protons into the cell (symport system) (By similarity)
D6B99_08475	ENOG4105C9F	isomerase
D6B99_08505	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
D6B99_08540	ENOG4105FTV	AraC Family Transcriptional Regulator
D6B99_08545	ENOG4105CNT	hydrolase family 2
D6B99_08575	ENOG4108M26	parallel beta-helix repeat protein
D6B99_08660	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_08670	ENOG4105CNT	hydrolase family 2
D6B99_08690	ENOG4105CNT	hydrolase family 2
D6B99_08700	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
D6B99_08705	ENOG4107QZF	nitrite reductase NADPH large subunit
D6B99_08730	ENOG4107QIW	Catalytic subunit of the periplasmic nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC, thus allowing electron flow between membrane and periplasm. Essential function for nitrate assimilation and may have a role in anaerobic metabolism (By similarity)
D6B99_08735	ENOG4105VCQ	rubredoxin
D6B99_08750	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
D6B99_08775	ENOG4108ZAF	Molybdopterin
D6B99_08780	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
D6B99_08805	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
D6B99_08810	ENOG4105E2Z	phosphate ABC transporter (Permease
D6B99_08835	ENOG4105EE1	crotonyl-CoA reductase
D6B99_08845	ENOG41089BK	Glutamine amido-transferase
D6B99_08860	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
D6B99_08870	ENOG4105DWF	phosphomethylpyrimidine kinase
D6B99_08875	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
D6B99_08880	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
D6B99_08885	ENOG4105D41	biosynthesis protein thiH
D6B99_08915	ENOG4105CWX	Alpha-1,2-mannosidase
D6B99_08940	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_08970	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_08975	ENOG4105ETE	Transcriptional regulator (LacI family
D6B99_08980	ENOG4107SET	aldo keto reductase
D6B99_08985	ENOG4105ID8	Transcriptional regulator, ARAC family
D6B99_08990	ENOG4108ETT	Dehydrogenase
D6B99_09040	ENOG4105E4I	Glycoside hydrolase family 28
D6B99_09045	ENOG4105DFK	Polyphosphate glucokinase
D6B99_09070	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_09075	ENOG4105ETE	Transcriptional regulator (LacI family
D6B99_09080	ENOG4105ETE	Transcriptional regulator (LacI family
D6B99_09090	ENOG4107R3N	Filamentation induced by cAMP protein fic
D6B99_09100	ENOG4105CHR	reductase
D6B99_09105	ENOG4105CB2	alcohol dehydrogenase
D6B99_09110	ENOG4105CHR	reductase
D6B99_09115	ENOG4105CIS	alcohol dehydrogenase
D6B99_09125	ENOG4107QMZ	Dehydrogenase
D6B99_09135	ENOG4105D5Q	Arginine ornithine antiporter
D6B99_09140	ENOG4105CTU	Proline racemase
D6B99_09145	ENOG4105CZJ	Aldehyde dehydrogenase
D6B99_09165	ENOG4105EX0	alpha-galactosidase
D6B99_09215	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_09235	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
D6B99_09240	ENOG4105CJQ	hydrolase, family 31
D6B99_09245	ENOG4105E6M	Sulphatase-modifying factor protein
D6B99_09280	ENOG4105ENN	converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity)
D6B99_09290	ENOG4105BZU	Histidine kinase
D6B99_09295	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D6B99_09305	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_09315	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
D6B99_09320	ENOG4105ENH	Sulfatase
D6B99_09335	ENOG4107QRH	Arylsulfatase (Ec 3.1.6.1)
D6B99_09345	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D6B99_09355	ENOG4105D7V	transposase
D6B99_09420	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
D6B99_09470	ENOG4105CPK	Glycosyl transferase (Group 1
D6B99_09480	ENOG4105WG6	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
D6B99_09485	ENOG4105VG0	50S ribosomal protein l34
D6B99_09500	ENOG41061P3	phosphosulfolactate synthase
D6B99_09505	ENOG4105E2X	shikimate dehydrogenase
D6B99_09520	ENOG4105E78	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring (By similarity)
D6B99_09525	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D6B99_09550	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
D6B99_09610	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
D6B99_09625	ENOG4105DQ4	alcohol dehydrogenase
D6B99_09650	ENOG4105IJY	hydroxylase
D6B99_09675	ENOG4105EWK	phytoene
D6B99_09695	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D6B99_09700	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
D6B99_09705	ENOG4105CXT	aspartate transcarbamylase
D6B99_09710	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D6B99_09730	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
D6B99_09745	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
D6B99_09750	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
D6B99_09755	ENOG4105D2N	Aldolase
D6B99_09765	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
D6B99_09800	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
D6B99_09815	ENOG4105BZU	Histidine kinase
D6B99_09820	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D6B99_09835	ENOG4105DF6	Fe-S oxidoreductase
D6B99_09840	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
D6B99_09860	ENOG4105CXW	Synthesizes alpha-1,4-glucan chains using ADP-glucose (By similarity)
D6B99_09865	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
D6B99_09870	ENOG4105CTX	dehydratase
D6B99_09875	ENOG4107QZW	Altronate oxidoreductase
D6B99_09880	ENOG4105F5H	Glycosyl Hydrolase Family 88
D6B99_09905	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_09915	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_09930	ENOG4105E4I	Glycoside hydrolase family 28
D6B99_09950	ENOG4107TDE	lipolytic protein G-D-S-L family
D6B99_09955	ENOG4107TDE	lipolytic protein G-D-S-L family
D6B99_09960	ENOG4105ETE	Transcriptional regulator (LacI family
D6B99_09980	ENOG4105EAA	nucleoside
D6B99_09990	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D6B99_09995	ENOG4105C2X	Arabinose 5-phosphate isomerase
D6B99_10005	ENOG4105DFS	Conserved Protein
D6B99_10015	ENOG4105DC1	bifunctional purine biosynthesis protein purh
D6B99_10030	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
D6B99_10035	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
D6B99_10040	ENOG4105CM2	brancheD-chain amino acid aminotransferase
D6B99_10055	ENOG4105NQN	cytochrome C
D6B99_10075	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D6B99_10085	ENOG4105CPP	Dehydrogenase, E1 component
D6B99_10090	ENOG4105C26	Dehydrogenase
D6B99_10100	ENOG4105DRY	peptidase s9 prolyl oligopeptidase active site domain protein
D6B99_10105	ENOG4107RQD	Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid (By similarity)
D6B99_10115	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
D6B99_10145	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
D6B99_10175	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
D6B99_10185	ENOG4105C1J	atp-dependent rna helicase
D6B99_10190	ENOG4107S1W	4-alpha-glucanotransferase
D6B99_10205	ENOG4105C28	cystathionine
D6B99_10240	ENOG4105DZ0	fad dependent oxidoreductase
D6B99_10270	ENOG4105CN9	Peptidase m42 family protein
D6B99_10335	ENOG4107THF	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
D6B99_10370	ENOG4105C72	UPF0176 protein
D6B99_10380	ENOG4105VJV	50s ribosomal protein L35
D6B99_10385	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
D6B99_10390	ENOG4105DP5	Catalyzes the biosynthesis of agmatine from arginine (By similarity)
D6B99_10395	ENOG4105CX6	glutaminyL-tRNA synthetase
D6B99_10415	ENOG4105D7V	transposase
D6B99_10425	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
D6B99_10445	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_10460	ENOG4105DW3	Response regulator receiver modulated metal dependent phosphohydrolase
D6B99_10485	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
D6B99_10490	ENOG4105C30	Nad-dependent epimerase dehydratase
D6B99_10495	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
D6B99_10540	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
D6B99_10545	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
D6B99_10555	ENOG4107QQG	Dehydrogenase
D6B99_10605	ENOG4105D0H	Alpha-glucuronidase (EC 3.2.1.139)
D6B99_10610	ENOG4105DT9	hydrolase family 43
D6B99_10615	ENOG4105CGS	Alpha-glucosidase
D6B99_10620	ENOG4105E4I	Glycoside hydrolase family 28
D6B99_10645	ENOG4108MYR	Secreted protein
D6B99_10660	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_10685	ENOG4105D7V	transposase
D6B99_10700	ENOG4105DYC	esterase
D6B99_10705	ENOG4105DYC	esterase
D6B99_10715	ENOG4105EK5	Glycoside hydrolase family 8
D6B99_10725	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
D6B99_10735	ENOG4107SYN	Glycosyl hydrolases family 43
D6B99_10765	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_10775	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
D6B99_10780	ENOG4107QNK	)-transporter
D6B99_10785	ENOG4105C93	Xylose Isomerase
D6B99_10790	ENOG4105CMG	Carbohydrate kinase
D6B99_10795	ENOG4105ETE	Transcriptional regulator (LacI family
D6B99_10805	ENOG4105D9F	endo-1,4-beta-xylanase (EC 3.2.1.8)
D6B99_10840	ENOG4105C98	muts2 protein
D6B99_10845	ENOG4107T6Z	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
D6B99_10865	ENOG4105CN1	protease
D6B99_10885	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
D6B99_10890	ENOG4107T8Q	Glycosyl transferase (Group 1
D6B99_10895	ENOG4105EAG	UDP-N-acetylglucosamine 2-epimerase
D6B99_10900	ENOG4107S6X	Glycosyl transferase, family 2
D6B99_10905	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
D6B99_10915	ENOG4105CCF	Lysine exporter protein (Lyse ygga)
D6B99_10930	ENOG4108KSB	HipA-like N-terminal domain
D6B99_10935	ENOG4105CAF	HipA N-terminal domain protein
D6B99_10950	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
D6B99_10955	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
D6B99_10960	ENOG4105DR4	Methyltransferase
D6B99_10975	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
D6B99_10980	ENOG4107XPB	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D6B99_10985	ENOG4105CAY	ferredoxin--nadp reductase
D6B99_10995	ENOG4105E0X	reductase
D6B99_11010	ENOG4105D7V	transposase
D6B99_11025	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
D6B99_11030	ENOG4108R6K	riboflavin synthase, subunit alpha
D6B99_11040	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
D6B99_11045	ENOG4105ENJ	RND efflux system, outer membrane lipoprotein
D6B99_11055	ENOG4105ENT	Efflux transporter rnd family, mfp subunit
D6B99_11080	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_11100	ENOG4105C37	(CBS) domain
D6B99_11110	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
D6B99_11140	ENOG4106BRA	Membrane
D6B99_11145	ENOG4105KVH	Transcriptional regulator
D6B99_11180	ENOG41082BM	Transcriptional regulator, arsr family
D6B99_11205	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
D6B99_11220	ENOG4105U5Y	Transcriptional regulator
D6B99_11225	ENOG4105DXN	mazG family
D6B99_11230	ENOG4105ES5	Histidine kinase
D6B99_11235	ENOG4105NWN	ApaG protein
D6B99_11245	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
D6B99_11270	ENOG4105D7V	transposase
D6B99_11275	ENOG4105EAY	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
D6B99_11290	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
D6B99_11295	ENOG4107ZNS	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
D6B99_11300	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
D6B99_11305	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D6B99_11315	ENOG4105D9R	oxidoreductase
D6B99_11325	ENOG4105C75	arginyL-tRNA synthetase
D6B99_11375	ENOG4105D7V	transposase
D6B99_11430	ENOG4105CNN	ABC, transporter
D6B99_11435	ENOG4105C2J	ABC transporter
D6B99_11445	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
D6B99_11450	ENOG4108IUS	Transketolase
D6B99_11455	ENOG4108HHA	Transketolase
D6B99_11465	ENOG4105E98	transcriptional regulator DeoR family
D6B99_11475	ENOG4105CHR	reductase
D6B99_11480	ENOG4107S5I	aldo keto reductase
D6B99_11500	ENOG4107YXA	Transcriptional regulator, BadM Rrf2 family
D6B99_11505	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
D6B99_11525	ENOG4107W2A	UPF0173 metal-dependent hydrolase
D6B99_11530	ENOG4107QJE	Chromosome Partitioning Protein
D6B99_11535	ENOG4105FA0	parb-like partition protein
D6B99_11545	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
D6B99_11550	ENOG4105CQB	FAD linked oxidase domain protein
D6B99_11560	ENOG4108URH	decarboxylase
D6B99_11565	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
D6B99_11590	ENOG4105D7V	transposase
D6B99_11620	ENOG4107H6E	
D6B99_11725	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
D6B99_11840	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
D6B99_11875	ENOG4105MHT	Transcriptional regulator, ARSR family
D6B99_11895	ENOG4108IA2	Sodium pantothenate symporter
D6B99_11935	ENOG4105CNT	hydrolase family 2
D6B99_11950	ENOG4105CZZ	Alpha-N-arabinofuranosidase (EC 3.2.1.55)
D6B99_11980	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_11990	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_12005	ENOG4105BZU	Histidine kinase
D6B99_12025	ENOG4108HRK	Histidine kinase
D6B99_12030	ENOG4105DY9	regulatoR
D6B99_12050	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
D6B99_12065	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D6B99_12080	ENOG4105D9K	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions (By similarity)
D6B99_12090	ENOG4108R80	One of the components of the high-affinity ATP-driven potassium transport (or KDP) system, which catalyzes the hydrolysis of ATP coupled with the exchange of hydrogen and potassium ions. The C subunit may be involved in assembly of the KDP complex (By similarity)
D6B99_12155	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_12175	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_12185	ENOG4105CNT	hydrolase family 2
D6B99_12200	ENOG4105CNT	hydrolase family 2
D6B99_12205	ENOG4105CX8	fg-gap repeat protein
D6B99_12215	ENOG4107TDE	lipolytic protein G-D-S-L family
D6B99_12240	ENOG41061MV	Arylsulfatase
D6B99_12245	ENOG4107TDE	lipolytic protein G-D-S-L family
D6B99_12250	ENOG4105TT1	Ragb susd domain-containing protein
D6B99_12255	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_12260	ENOG4105D7V	transposase
D6B99_12265	ENOG4105D7V	transposase
D6B99_12315	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_12370	ENOG4108YYC	ycei family
D6B99_12390	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D6B99_12400	ENOG4105ID8	Transcriptional regulator, ARAC family
D6B99_12405	ENOG4108JA1	polyketide synthase
D6B99_12445	ENOG4105FTV	AraC Family Transcriptional Regulator
D6B99_12485	ENOG4107RQ5	Methylates ribosomal protein L11 (By similarity)
D6B99_12510	ENOG4105DEU	major facilitator superfamily
D6B99_12515	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
D6B99_12520	ENOG4105C6E	dna polymerase iii
D6B99_12540	ENOG4105D17	glycoside hydrolase, family 3 domain protein
D6B99_12545	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
D6B99_12555	ENOG4105M10	Involved in the anomeric conversion of L-rhamnose (By similarity)
D6B99_12565	ENOG4105EKQ	RNA-directed DNA polymerase
D6B99_12575	ENOG4107P8H	Protein of unknown function (DUF1328)
D6B99_12585	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
D6B99_12590	ENOG4105CDZ	Carboxymethylenebutenolidase (EC 3.1.1.45)
D6B99_12595	ENOG4105C0B	DNA polymerase III (alpha subunit)
D6B99_12600	ENOG4105CPC	Aldo Keto reductase
D6B99_12605	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D6B99_12610	ENOG4105E2D	ec 3.2.1.52
D6B99_12615	ENOG4105CE4	GlcNAc 6-P deacetylase
D6B99_12650	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
D6B99_12660	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_12665	ENOG4105JXH	GntR family transcriptional regulator
D6B99_12670	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
D6B99_12675	ENOG4105CH2	amidohydrolase
D6B99_12695	ENOG4105DG4	malate L-lactate dehydrogenase
D6B99_12705	ENOG4107YH6	single-stranded DNA-binding protein
D6B99_12715	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
D6B99_12720	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
D6B99_12735	ENOG4105C0H	protease
D6B99_12740	ENOG4108IUX	(ABC) transporter
D6B99_12755	ENOG4105D6J	arsenicaL-resistance protein
D6B99_12800	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
D6B99_12850	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)
D6B99_12855	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
D6B99_12875	ENOG4107SET	aldo keto reductase
D6B99_12880	ENOG4105DQ4	alcohol dehydrogenase
D6B99_12895	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
D6B99_12920	ENOG4105E2D	ec 3.2.1.52
D6B99_12930	ENOG4105CNT	hydrolase family 2
D6B99_12950	ENOG4106AM8	polysaccharide lyase family 8
D6B99_12975	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_12980	ENOG4105TT1	Ragb susd domain-containing protein
D6B99_12985	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_13000	ENOG4105CAT	Cytidine monophosphate kinase
D6B99_13010	ENOG4105CTX	dehydratase
D6B99_13015	ENOG4105CHR	reductase
D6B99_13025	ENOG4105ERH	Fumarylacetoacetate hydrolase
D6B99_13030	ENOG41061TZ	Short-chain dehydrogenase reductase Sdr
D6B99_13040	ENOG4105QJH	Domain of unknown function (DUF718)
D6B99_13045	ENOG4105EDR	glucose galactose transporter
D6B99_13075	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
D6B99_13085	ENOG4105C3F	Signal peptidase i
D6B99_13105	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
D6B99_13135	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_13150	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
D6B99_13155	ENOG4105CWX	Alpha-1,2-mannosidase
D6B99_13160	ENOG4107RDT	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
D6B99_13205	ENOG4105DVY	radical SAM domain protein
D6B99_13210	ENOG4108IFH	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
D6B99_13225	ENOG4105W2Z	cytochrome C, class I
D6B99_13230	ENOG4108Z6B	deaminase
D6B99_13235	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
D6B99_13245	ENOG4108Y6J	UPF0403 protein
D6B99_13250	ENOG4105VN1	Heat shock protein
D6B99_13255	ENOG4105C0H	protease
D6B99_13265	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
D6B99_13270	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
D6B99_13280	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
D6B99_13325	ENOG4108HKT	sucrose-6-phosphate hydrolase
D6B99_13330	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
D6B99_13335	ENOG4105VG1	fes assembly suf system protein
D6B99_13360	ENOG4105DSS	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation (By similarity)
D6B99_13370	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
D6B99_13390	ENOG4105C37	(CBS) domain
D6B99_13395	ENOG4109015	Biopolymer transport protein exbD tolR
D6B99_13435	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_13465	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
D6B99_13470	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
D6B99_13475	ENOG4107Z65	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
D6B99_13480	ENOG4105VHG	atp synthase
D6B99_13485	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
D6B99_13500	ENOG4105CGM	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis (By similarity)
D6B99_13515	ENOG4107RCQ	(CBS) domain
D6B99_13525	ENOG4107RJ9	Cell division protein FtsX
D6B99_13530	ENOG4105C8T	Leucyl-tRNA synthetase
D6B99_13545	ENOG4105K5M	30s ribosomal protein S16
D6B99_13550	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
D6B99_13580	ENOG4107EES	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide the precursor of murein (By similarity)
D6B99_13590	ENOG4105CJI	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
D6B99_13600	ENOG4107QJZ	Glycosyl transferase, family 2
D6B99_13610	ENOG4107R51	Glycosyl transferase, family 2
D6B99_13615	ENOG4107R7I	amino acid
D6B99_13625	ENOG4105CFB	Gamma-glutamyltranspeptidase (EC 2.3.2.2)
D6B99_13635	ENOG4108X7C	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
D6B99_13640	ENOG4105D3R	alkyl hydroperoxide reductase
D6B99_13650	ENOG4108ZT0	50S ribosomal protein l17
D6B99_13655	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D6B99_13660	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
D6B99_13665	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
D6B99_13670	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D6B99_13675	ENOG410864M	50S ribosomal protein L36
D6B99_13680	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
D6B99_13700	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
D6B99_13705	ENOG4105D7V	transposase
D6B99_13720	ENOG4105ESV	Glycosyl transferase, family 4
D6B99_13725	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
D6B99_13735	ENOG41085FR	LemA family
D6B99_13750	ENOG410635A	Membrane
D6B99_13760	ENOG4107EER	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component (By similarity)
D6B99_13765	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
D6B99_13775	ENOG4105C11	sulfate adenylyltransferase), subunit 2
D6B99_13785	ENOG4105BZU	Histidine kinase
D6B99_13790	ENOG4105MDS	4-oxalocrotonate tautomerase
D6B99_13800	ENOG4105DY9	regulatoR
D6B99_13805	ENOG4105C2F	Histidine kinase
D6B99_13810	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
D6B99_13815	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
D6B99_13845	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D6B99_13855	ENOG4105DTQ	mandelate racemase muconate lactonizing
D6B99_13860	ENOG4105C10	Electron transfer flavoprotein
D6B99_13865	ENOG4105BZJ	Electron transfer flavoprotein
D6B99_13905	ENOG4105CJ1	ABC, transporter
D6B99_13915	ENOG4105F10	Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP (By similarity)
D6B99_13940	ENOG4105CPE	K01197 hyaluronoglucosaminidase EC 3.2.1.35
D6B99_13950	ENOG4105C3R	Methionine synthase
D6B99_13955	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
D6B99_13970	ENOG4105C4R	Atp-dependent dna helicase
D6B99_14000	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
D6B99_14010	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
D6B99_14040	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
D6B99_14045	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
D6B99_14050	ENOG4105SFS	phosphoesterase RecJ domain protein
D6B99_14060	ENOG4105CTD	carboxy-peptidase
D6B99_14070	ENOG4107QKV	phosphomannomutase
D6B99_14075	ENOG4107QI6	Cysteine desulfurase
D6B99_14080	ENOG4105CD3	dihydroorotase
D6B99_14090	ENOG4105CKK	Glycosyl transferase, family 2
D6B99_14095	ENOG4105CHM	Aminotransferase
D6B99_14100	ENOG4106M28	alanine racemase domain protein
D6B99_14110	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
D6B99_14125	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
D6B99_14130	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D6B99_14145	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
D6B99_14150	ENOG4105C3J	Cysteine desulfurase
D6B99_14155	ENOG4105DU1	integral membrane protein, terc
D6B99_14165	ENOG4105DFH	Transport of potassium into the cell (By similarity)
D6B99_14175	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
D6B99_14190	ENOG4105CBG	Sulfatase
D6B99_14195	ENOG4105E2D	ec 3.2.1.52
D6B99_14230	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
D6B99_14245	ENOG4105CWX	Alpha-1,2-mannosidase
D6B99_14285	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_14300	ENOG4105CWX	Alpha-1,2-mannosidase
D6B99_14315	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_14320	ENOG4105E98	transcriptional regulator DeoR family
D6B99_14355	ENOG4105C4R	Atp-dependent dna helicase
D6B99_14360	ENOG4105ETE	Transcriptional regulator (LacI family
D6B99_14370	ENOG4105EBE	Peptidase U61, LD-carboxypeptidase A
D6B99_14380	ENOG4105D7V	transposase
D6B99_14400	ENOG4105HHQ	6-phosphogluconolactonase (EC 3.1.1.31)
D6B99_14410	ENOG4105CBC	glutamate synthase
D6B99_14415	ENOG4105EEQ	Na H antiporter
D6B99_14420	ENOG4105DGW	oligopeptidase A
D6B99_14425	ENOG4107RF4	Phosphodiesterase
D6B99_14440	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
D6B99_14445	ENOG4108YYV	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity)
D6B99_14455	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_14460	ENOG4108S0S	Nucleotidyl transferase
D6B99_14470	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
D6B99_14475	ENOG4107ZHV	Transcriptional regulator
D6B99_14480	ENOG4105BZU	Histidine kinase
D6B99_14520	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
D6B99_14525	ENOG4106AM8	polysaccharide lyase family 8
D6B99_14530	ENOG4105DCI	Phosphohydrolase
D6B99_14535	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D6B99_14540	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
D6B99_14560	ENOG4105E2D	ec 3.2.1.52
D6B99_14565	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
D6B99_14575	ENOG4105D7W	serine acetyltransferase
D6B99_14580	ENOG4105C6T	cysteine synthase
D6B99_14585	ENOG4105DDQ	anthranilate synthase
D6B99_14590	ENOG4105CRQ	synthase (Component I)
D6B99_14600	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D6B99_14615	ENOG4105FJR	Lmbe family
D6B99_14625	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
D6B99_14630	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
D6B99_14715	ENOG4107RBB	ABC transporter, permease
D6B99_14720	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
D6B99_14730	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
D6B99_14735	ENOG4105EIZ	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
D6B99_14740	ENOG4105FBN	Acid phosphatase
D6B99_14750	ENOG41090A1	ferritin
D6B99_14755	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
D6B99_14760	ENOG4105CE9	30S ribosomal protein S2
D6B99_14765	ENOG4108UJD	30S ribosomal protein S9
D6B99_14770	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
D6B99_14775	ENOG4108UJU	UPF0301 protein
D6B99_14780	ENOG4108R99	pseudouridine synthase
D6B99_14790	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
D6B99_14805	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
D6B99_14810	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
D6B99_14840	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_14860	ENOG4105FE8	tRNA (Guanosine-2'-O-)-methyltransferase
D6B99_14865	ENOG4105CFH	Aspartokinase
D6B99_14870	ENOG4107RDY	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
D6B99_14880	ENOG4105K64	Glycosyl transferase, family 2
D6B99_14885	ENOG4107QUV	Domain protein
D6B99_14890	ENOG4105CFX	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
D6B99_14920	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D6B99_14940	ENOG4105KTH	gatB Yqey
D6B99_14960	ENOG4105F37	PsaA and PsaB bind P700, the primary electron donor of photosystem I (PSI), as well as the electron acceptors A0, A1 and FX. PSI is a plastocyanin cytochrome c6-ferredoxin oxidoreductase, converting photonic excitation into a charge separation, which transfers an electron from the donor P700 chlorophyll pair to the spectroscopically characterized acceptors A0, A1, FX, FA and FB in turn. Oxidized P700 is reduced on the lumenal side of the thylakoid membrane by plastocyanin or cytochrome c6
D6B99_14970	ENOG4105DWV	Homoserine O-trans-acetylase
D6B99_14975	ENOG4105D6E	homoserine dehydrogenase
D6B99_14980	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
D6B99_15015	ENOG4105DGM	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
D6B99_15020	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
D6B99_15045	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
D6B99_15060	ENOG4107QSV	RmuC domain protein
D6B99_15085	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
D6B99_15090	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
D6B99_15105	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
D6B99_15110	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
D6B99_15150	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
D6B99_15155	ENOG4108IUK	alpha amylase, catalytic
D6B99_15175	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_15180	ENOG4105ETE	Transcriptional regulator (LacI family
D6B99_15195	ENOG4108RCS	geranylgeranylglyceryl phosphate synthase
D6B99_15200	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
D6B99_15205	ENOG4108V6E	Cell division protein mraZ
D6B99_15210	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
D6B99_15220	ENOG4105CJN	penicillin-binding protein
D6B99_15225	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
D6B99_15230	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
D6B99_15235	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
D6B99_15240	ENOG4105CNI	cell division protein FtsW
D6B99_15245	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
D6B99_15250	ENOG4105DFU	Cell wall formation (By similarity)
D6B99_15260	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
D6B99_15265	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
D6B99_15275	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
D6B99_15300	ENOG4107QJZ	Glycosyl transferase, family 2
D6B99_15310	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
D6B99_15315	ENOG4105BZU	Histidine kinase
D6B99_15320	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D6B99_15335	ENOG4105BZU	Histidine kinase
D6B99_15340	ENOG4105BZU	Histidine kinase
D6B99_15350	ENOG4105BZU	Histidine kinase
D6B99_15375	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
D6B99_15380	ENOG4105DZP	Membrane-associated zinc metalloprotease
D6B99_15395	ENOG4105F55	Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate (By similarity)
D6B99_15410	ENOG41083DV	d,d-heptose 1,7-bisphosphate phosphatase
D6B99_15415	ENOG4105BZU	Histidine kinase
D6B99_15420	ENOG4108JA2	transcriptioN-repair coupling factor
D6B99_15435	ENOG4106AM8	polysaccharide lyase family 8
D6B99_15445	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D6B99_15450	ENOG4108WBT	adenosyltransferase
D6B99_15455	ENOG4105C19	ABC transporter
D6B99_15460	ENOG410853W	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
D6B99_15465	ENOG4107S47	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) (By similarity)
D6B99_15480	ENOG4105CB5	ATP-dependent DNA helicase recG
D6B99_15525	ENOG4105I7Z	Short-chain dehydrogenase reductase Sdr
D6B99_15530	ENOG4105ECQ	AraC Family Transcriptional Regulator
D6B99_15540	ENOG4107R3N	Filamentation induced by cAMP protein fic
D6B99_15555	ENOG4105E3B	Multicopper oxidase
D6B99_15570	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
D6B99_15580	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
D6B99_15585	ENOG4105K46	50S ribosomal protein l27
D6B99_15605	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D6B99_15625	ENOG4105PGZ	NB-ARC domain
D6B99_15630	ENOG4105CBX	hi0933 family
D6B99_15640	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
D6B99_15645	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
D6B99_15650	ENOG41084HK	50S ribosomal protein L30
D6B99_15655	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
D6B99_15660	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
D6B99_15665	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
D6B99_15670	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
D6B99_15675	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
D6B99_15680	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
D6B99_15685	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
D6B99_15690	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
D6B99_15695	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
D6B99_15700	ENOG4108628	50s ribosomal protein l29
D6B99_15705	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
D6B99_15710	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
D6B99_15720	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
D6B99_15725	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
D6B99_15730	ENOG41082S5	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
D6B99_15735	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
D6B99_15740	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
D6B99_15745	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
D6B99_15755	ENOG4105CNT	hydrolase family 2
D6B99_15775	ENOG4105E2V	Glycosyltransferase 36
D6B99_15780	ENOG4107RAQ	aminopeptidase
D6B99_15785	ENOG4108IUZ	ABC transporter
D6B99_15805	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
D6B99_15835	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
D6B99_15840	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
D6B99_15845	ENOG4105CHV	Transcription elongation factor NusA
D6B99_15850	ENOG41090IP	Required for maturation of 30S ribosomal subunits (By similarity)
D6B99_15855	ENOG4105ENH	Sulfatase
D6B99_15865	ENOG4105C5S	asparaginyl-tRNA synthetase
D6B99_15890	ENOG4107QI1	Mate efflux family protein
D6B99_15895	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
D6B99_15905	ENOG4105CHH	sulfate transporter
D6B99_15920	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
D6B99_15930	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
D6B99_15935	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
D6B99_15940	ENOG4105CSR	polyphosphate kinase 2
D6B99_15950	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
D6B99_15955	ENOG4105DVP	Adenine-specific
D6B99_15965	ENOG4105ZMH	deoxynucleoside kinase
D6B99_15975	ENOG4108ZJ4	polysaccharide deacetylase
D6B99_16000	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
D6B99_16015	ENOG4105EHZ	conserved protein UCP016719
D6B99_16020	ENOG4105C0D	helicase
D6B99_16025	ENOG4108S4H	thioesterase Superfamily protein
D6B99_16030	ENOG4105PGM	cation diffusion facilitator family transporter
D6B99_16035	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
D6B99_16040	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
D6B99_16045	ENOG4107VNI	ribosomal protein l10
D6B99_16050	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
D6B99_16055	ENOG4106N3A	copper homeostasis protein cutc
D6B99_16085	ENOG41083MR	nifu domain-containing protein
D6B99_16090	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
D6B99_16095	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
D6B99_16100	ENOG4105DFU	Cell wall formation (By similarity)
D6B99_16125	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_16155	ENOG4105ETE	Transcriptional regulator (LacI family
D6B99_16160	ENOG4105E4P	ATPase (AAA
D6B99_16215	ENOG4107QMH	DNA methylase
D6B99_16225	ENOG4108IYS	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D6B99_16235	ENOG4107ZT5	Thiol disulfide interchange protein
D6B99_16330	ENOG4105D5D	udp-galactopyranose mutase
D6B99_16345	ENOG4108JJA	ABC, transporter
D6B99_16350	ENOG4105C42	Type I secretion membrane fusion protein (HlyD
D6B99_16465	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_16545	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
D6B99_16555	ENOG4105KNE	Phosphatidate cytidylyltransferase
D6B99_16560	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
D6B99_16565	ENOG4105E66	phosphoriboisomerase A
D6B99_16580	ENOG4105CPQ	Dehydrogenase
D6B99_16585	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
D6B99_16595	ENOG4105DUX	Transporter
D6B99_16605	ENOG4105DWT	malate dehydrogenase (quinone)
D6B99_16645	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
D6B99_16650	ENOG4108M3J	Dehydrogenase
D6B99_16655	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
D6B99_16670	ENOG4107R8N	Glycosyl transferase, family 2
D6B99_16690	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
D6B99_16700	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
D6B99_16710	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
D6B99_16715	ENOG4105CJX	Molecular chaperone. Has ATPase activity (By similarity)
D6B99_16735	ENOG4105MSB	protein, conserved in bacteria
D6B99_16740	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
D6B99_16745	ENOG4105CIY	formyltetrahydrofolate deformylase
D6B99_16765	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
D6B99_16770	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
D6B99_16775	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
D6B99_16795	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
D6B99_16800	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D6B99_16805	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
D6B99_16840	ENOG4105EUJ	GTP cyclohydrolase i
D6B99_16845	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
D6B99_16850	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
D6B99_16855	ENOG4105M08	Membrane
D6B99_16860	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
D6B99_16865	ENOG4105E2D	ec 3.2.1.52
D6B99_16870	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
D6B99_16880	ENOG4105SYT	Methylenetetrahydrofolate reductase
D6B99_16935	ENOG4108IQE	Amp-dependent synthetase and ligase
D6B99_16945	ENOG4105C12	Phosphoribosylglycinamide synthetase
D6B99_16975	ENOG4107TE5	Lipid kinase
D6B99_16985	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
D6B99_16995	ENOG41080AX	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
D6B99_17000	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
D6B99_17010	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
D6B99_17015	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
D6B99_17035	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
D6B99_17065	ENOG4105C27	TonB-dependent Receptor Plug
D6B99_17085	ENOG4105CAK	Cell division ATP-binding protein ftsE
D6B99_17095	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
D6B99_17100	ENOG4105D52	delta-aminolevulinic acid dehydratase
D6B99_17105	ENOG4105DBS	Key enzyme in heme biosynthesis. Catalyzes the oxidative decarboxylation of propionic acid side chains of rings A and B of coproporphyrinogen III (By similarity)
D6B99_17120	ENOG4105CFZ	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III (By similarity)
D6B99_17130	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
D6B99_17135	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
D6B99_17140	ENOG4105E2R	ROK family
D6B99_17165	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
D6B99_17175	ENOG4105EGD	dinuclear metal center protein, YbgI family
D6B99_17180	ENOG4105E63	Pfam:DUF178
D6B99_17190	ENOG4108YYC	ycei family
D6B99_17200	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
D6B99_17205	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
D6B99_17220	ENOG4105KIR	Thiol-disulfide oxidoreductase dcc
D6B99_17235	ENOG4105EEI	dihydropteroate synthase
D6B99_17240	ENOG4105VXP	Protein of unknown function DUF86