locus-tag	class	description
Arch_0001	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
Arch_0002	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
Arch_0003	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Arch_0005	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Arch_0006	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Arch_0014	ENOG4105E2R	ROK family
Arch_0015	ENOG4105D6U	Sodium Glutamate Symporter
Arch_0019	ENOG4105DAA	L-lactate
Arch_0020	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
Arch_0021	ENOG4107QR9	Iron-sulfur cluster binding protein
Arch_0022	ENOG41080R8	Conserved Protein
Arch_0028	ENOG4105C94	Transporter
Arch_0037	ENOG4107QKS	N-acylglucosamine 2-epimerase
Arch_0039	ENOG4107QNK	)-transporter
Arch_0041	ENOG4105CJK	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) (By similarity)
Arch_0043	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
Arch_0045	ENOG4105EDK	PfkB domain protein
Arch_0047	ENOG4105DH8	myo-inositol catabolism
Arch_0048	ENOG4108HRG	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG) (By similarity)
Arch_0049	ENOG4105C26	Dehydrogenase
Arch_0051	ENOG4105DKQ	ROK family
Arch_0054	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
Arch_0056	ENOG4105DKQ	ROK family
Arch_0060	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
Arch_0067	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
Arch_0068	ENOG4105EY8	ABC transporter
Arch_0069	ENOG4105MFV	ABC-2 type transporter
Arch_0076	ENOG4105CKK	Glycosyl transferase, family 2
Arch_0081	ENOG4105KPE	licD family
Arch_0082	ENOG4106MCE	EamA-like transporter family
Arch_0084	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
Arch_0089	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
Arch_0092	ENOG4105H63	Glycosyl transferase, family 2
Arch_0094	ENOG4106MCE	EamA-like transporter family
Arch_0098	ENOG4105ZJT	Cell division protein CrgA
Arch_0099	ENOG4108U4N	(sortase) family
Arch_0101	ENOG410836F	Transposase
Arch_0102	ENOG4105D9P	serine threonine protein kinase
Arch_0103	ENOG4105CJN	penicillin-binding protein
Arch_0106	ENOG4105HZM	Fha domain containing protein
Arch_0107	ENOG4105IDI	abc transporter atp-binding protein
Arch_0108	ENOG4105EN6	Membrane
Arch_0110	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Arch_0113	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
Arch_0114	ENOG4106762	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD) (By similarity)
Arch_0116	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
Arch_0117	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
Arch_0124	ENOG4108JEH	abc transporter atp-binding protein
Arch_0125	ENOG4105E5Q	amino acid AbC transporter
Arch_0127	ENOG4105CQ7	ATP-dependent helicase
Arch_0130	ENOG4108TZY	GntR Family Transcriptional Regulator
Arch_0136	ENOG4107T5V	SNARE associated Golgi
Arch_0137	ENOG41082T9	Membrane
Arch_0140	ENOG4105FF2	Type I DHQase
Arch_0141	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
Arch_0142	ENOG4105DSE	periplasmic solute binding protein
Arch_0143	ENOG4105DIK	(ABC) transporter
Arch_0144	ENOG4105CC5	ABC transporter
Arch_0145	ENOG4107RBD	ABC, transporter
Arch_0146	ENOG4107R5H	iron (metal) dependent repressor, dtxr family
Arch_0147	ENOG4105DHP	deoxycytidine triphosphate deaminase
Arch_0148	ENOG4105D65	subunit l
Arch_0149	ENOG4105MKQ	Monovalent cation H antiporter subunit C
Arch_0150	ENOG4108JPZ	Monovalent cation H antiporter subunit D
Arch_0155	ENOG4105C4Y	ABC transporter
Arch_0157	ENOG4108UCS	ABC, transporter
Arch_0159	ENOG4105DRS	transport system, permease
Arch_0161	ENOG4105WEM	extracellular solute-binding protein
Arch_0166	ENOG4108VK3	Cupin 2 Conserved Barrel Domain Protein
Arch_0168	ENOG4105CFG	Acts as a chaperone (By similarity)
Arch_0169	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
Arch_0170	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Arch_0171	ENOG4105KNI	merR family transcriptional Regulator
Arch_0172	ENOG4105P8F	nudix hydrolase
Arch_0175	ENOG4108Z66	YbaK ebsC protein
Arch_0178	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
Arch_0180	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Arch_0181	ENOG4105C85	amino acid
Arch_0182	ENOG4105CZA	synthase
Arch_0185	ENOG4108IXY	short-chain dehydrogenase reductase
Arch_0187	ENOG4105M6F	mutator MutT protein
Arch_0192	ENOG4107RCW	fructose-bisphosphate aldolase
Arch_0195	ENOG4105D56	permease protein
Arch_0200	ENOG4105C0M	Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle (By similarity)
Arch_0201	ENOG4105C8V	SAICAR synthetase
Arch_0202	ENOG4107R37	Glutamate dehydrogenase
Arch_0211	ENOG4105E0X	reductase
Arch_0215	ENOG4107QJG	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
Arch_0218	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
Arch_0219	ENOG4105CJ3	phosphate transporter
Arch_0221	ENOG4105BZG	amino acid carrier protein
Arch_0224	ENOG4108X6U	May play a role in the intracellular transport of hydrophobic ligands
Arch_0225	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
Arch_0226	ENOG4108YYA	Hydrolyzes D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr). Could be a defense mechanism against a harmful effect of D-tyrosine (By similarity)
Arch_0227	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
Arch_0232	ENOG410836F	Transposase
Arch_0238	ENOG4105D3Y	Na H antiporter
Arch_0240	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
Arch_0241	ENOG4105EXC	Acyl-transferase
Arch_0246	ENOG4107SN7	NLP P60 protein
Arch_0247	ENOG4105F0N	pyrophosphate phospho-hydrolase
Arch_0248	ENOG4107RVU	D-Ala-D-Ala carboxypeptidase 3 (S13) family
Arch_0250	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
Arch_0251	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
Arch_0252	ENOG4105EUJ	GTP cyclohydrolase i
Arch_0259	ENOG4107QQT	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
Arch_0260	ENOG4108Z2X	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine (By similarity)
Arch_0261	ENOG4105CRK	lysyL-tRNA synthetase
Arch_0262	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
Arch_0263	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
Arch_0265	ENOG4105CHG	glycolate oxidase (iron-sulfur subunit)
Arch_0266	ENOG4108KJ0	anaerobic glycerol-3-phosphate dehydrogenase, subunit B
Arch_0267	ENOG4107R5Y	anaerobic glycerol-3-phosphate dehydrogenase, subunit A
Arch_0268	ENOG4105DKT	Transcriptional regulator
Arch_0269	ENOG4105CEN	a g-specific adenine glycosylase
Arch_0271	ENOG4105C57	major facilitator superfamily
Arch_0272	ENOG4105CSH	Transporter
Arch_0273	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
Arch_0276	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
Arch_0277	ENOG4107ZYR	domain protein
Arch_0278	ENOG4105CZN	Potassium uptake protein
Arch_0281	ENOG4108RH7	phosphoglycerate mutase
Arch_0285	ENOG4107SIQ	Naphthoate synthase
Arch_0287	ENOG4107TCW	O-succinylbenzoate synthase
Arch_0288	ENOG4105C4A	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) (By similarity)
Arch_0289	ENOG4105C0H	protease
Arch_0291	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
Arch_0292	ENOG4105P52	geranylgeranyl reductase
Arch_0294	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Arch_0295	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
Arch_0296	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Arch_0298	ENOG4107QIZ	NADH dehydrogenase
Arch_0299	ENOG4108IEH	NADH dehydrogenase subunit g
Arch_0300	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
Arch_0301	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Arch_0302	ENOG4105DF2	NADH dehydrogenase subunit j
Arch_0303	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Arch_0306	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
Arch_0308	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
Arch_0309	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
Arch_0319	ENOG4105EYH	Exonuclease
Arch_0320	ENOG4107RH8	nuclease SbcCD subunit D
Arch_0326	ENOG4105E06	May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (By similarity)
Arch_0327	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
Arch_0331	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
Arch_0332	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
Arch_0333	ENOG4105CE4	GlcNAc 6-P deacetylase
Arch_0334	ENOG4105EMN	RNA polymerase sigma factor
Arch_0346	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
Arch_0347	ENOG4105C37	(CBS) domain
Arch_0349	ENOG4105DR5	peptidase
Arch_0350	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
Arch_0351	ENOG4105C75	arginyL-tRNA synthetase
Arch_0355	ENOG4105VFB	Binds the 23S rRNA (By similarity)
Arch_0356	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
Arch_0357	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
Arch_0358	ENOG4107UIY	sua5 ycio yrdc ywlc family protein
Arch_0359	ENOG4105ESV	Glycosyl transferase, family 4
Arch_0361	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
Arch_0362	ENOG4105ZA1	atp synthase
Arch_0363	ENOG4107Z0K	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
Arch_0364	ENOG4108T62	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
Arch_0365	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
Arch_0366	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
Arch_0367	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
Arch_0368	ENOG4105KNM	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
Arch_0370	ENOG4105CYV	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures (By similarity)
Arch_0377	ENOG4105CG3	alpha amylase, catalytic region
Arch_0380	ENOG4105D56	permease protein
Arch_0381	ENOG4105EG2	ABC transporter, permease
Arch_0382	ENOG4108YYH	Nadph-dependent fmn reductase
Arch_0383	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
Arch_0384	ENOG41070F3	Catalyzes the ATP-dependent phosphorylation of maltose to maltose 1-phosphate. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, GlgE and GlgB (By similarity)
Arch_0386	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
Arch_0389	ENOG4105C31	Tryptophanyl-tRNA synthetase
Arch_0396	ENOG41063PX	domain protein
Arch_0398	ENOG4105DJZ	UPF0182 protein
Arch_0400	ENOG4105CZV	ABC transporter
Arch_0401	ENOG4105W8V	TRANSCRIPTIONAl REGULATOR GntR family
Arch_0409	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
Arch_0412	ENOG4105KRM	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
Arch_0415	ENOG4105WH1	Two component transcriptional regulator luxr family
Arch_0417	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
Arch_0418	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
Arch_0419	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Arch_0420	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
Arch_0421	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
Arch_0424	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Arch_0427	ENOG4105D0C	transport protein
Arch_0428	ENOG4108IJ0	Aspartate ammonia-lyase
Arch_0430	ENOG4105C6N	Formate acetyltransferase
Arch_0433	ENOG4105DFA	alanine racemase domain protein
Arch_0435	ENOG4105ETE	Transcriptional regulator (LacI family
Arch_0436	ENOG4105D2H	Uronic isomerase
Arch_0437	ENOG4105D7K	pfkb domain protein
Arch_0438	ENOG4108UHU	Aldolase
Arch_0439	ENOG4105CHZ	Catalyzes the dehydration of D-mannonate (By similarity)
Arch_0448	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
Arch_0450	ENOG4108IJ6	ABC transporter
Arch_0467	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
Arch_0468	ENOG4105C29	acyl-CoA thioesterase
Arch_0472	ENOG4108QTI	)-transporter
Arch_0474	ENOG4105C9K	Endothelin-converting enzyme 1
Arch_0476	ENOG4105D7W	serine acetyltransferase
Arch_0478	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
Arch_0482	ENOG4105CC5	ABC transporter
Arch_0483	ENOG4105DIK	(ABC) transporter
Arch_0486	ENOG4105D22	carbon starvation protein
Arch_0491	ENOG41088X7	deoxyguanosine kinase
Arch_0493	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
Arch_0496	ENOG4105DRS	transport system, permease
Arch_0513	ENOG4105ESF	Peptidoglycan binding domain protein
Arch_0517	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Arch_0521	ENOG4105CAR	Terminase, large subunit
Arch_0523	ENOG4105EFC	phage portal protein HK97 family
Arch_0526	ENOG4105WH1	Two component transcriptional regulator luxr family
Arch_0527	ENOG4105BZU	Histidine kinase
Arch_0529	ENOG4105WH1	Two component transcriptional regulator luxr family
Arch_0531	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
Arch_0536	ENOG41080FR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Arch_0539	ENOG4105W0E	50S ribosomal protein L33
Arch_0540	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
Arch_0541	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Arch_0542	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Arch_0544	ENOG4105FKQ	transcriptional regulator
Arch_0545	ENOG4105CXY	transporter
Arch_0546	ENOG4105ECY	inositol monophosphatase
Arch_0547	ENOG4108IQE	Amp-dependent synthetase and ligase
Arch_0549	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
Arch_0551	ENOG4105BZ1	(ABC) transporter
Arch_0552	ENOG4105BZ1	(ABC) transporter
Arch_0553	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
Arch_0554	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
Arch_0555	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
Arch_0556	ENOG4108UTZ	Dihydroxyacetone kinase
Arch_0559	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
Arch_0568	ENOG4105K5M	30s ribosomal protein S16
Arch_0569	ENOG41082KU	UPF0109 protein
Arch_0570	ENOG4107XUM	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
Arch_0571	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
Arch_0572	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
Arch_0573	ENOG4107QYR	Signal peptidase i
Arch_0574	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
Arch_0576	ENOG41080R2	UPF0102 protein
Arch_0577	ENOG4105C0P	Mg chelatase subunit ChlI
Arch_0579	ENOG4108IYT	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Arch_0580	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
Arch_0583	ENOG4105CE9	30S ribosomal protein S2
Arch_0584	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
Arch_0586	ENOG4105C10	Electron transfer flavoprotein
Arch_0587	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
Arch_0589	ENOG4105C85	amino acid
Arch_0599	ENOG41082I2	s4 domain protein
Arch_0600	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
Arch_0601	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
Arch_0603	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
Arch_0605	ENOG4105CEA	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) (By similarity)
Arch_0606	ENOG4105DZP	Membrane-associated zinc metalloprotease
Arch_0607	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
Arch_0608	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
Arch_0609	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
Arch_0611	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
Arch_0614	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
Arch_0615	ENOG4107ZPY	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
Arch_0616	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
Arch_0625	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
Arch_0627	ENOG4108JJB	ABC transporter
Arch_0630	ENOG4105EHG	Permease protein
Arch_0631	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
Arch_0632	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
Arch_0633	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
Arch_0637	ENOG4105CN5	Metallo-Beta-Lactamase
Arch_0639	ENOG4107RCV	ABC transporter, permease
Arch_0640	ENOG4105C4Y	ABC transporter
Arch_0641	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Arch_0642	ENOG4105BZU	Histidine kinase
Arch_0643	ENOG4105F9U	Dehydrogenase
Arch_0644	ENOG4107QZI	cell division protein FtsK
Arch_0646	ENOG4105CEV	competence damage-inducible protein
Arch_0647	ENOG4105WBV	Transcriptional regulator
Arch_0649	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
Arch_0650	ENOG4105Y3E	Modulates RecA activity (By similarity)
Arch_0651	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
Arch_0652	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
Arch_0653	ENOG4105DQ4	alcohol dehydrogenase
Arch_0654	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
Arch_0656	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
Arch_0658	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
Arch_0659	ENOG4105CEY	Amp-dependent synthetase and ligase
Arch_0663	ENOG4107VJY	DNA polymerase
Arch_0665	ENOG4108V6E	Cell division protein mraZ
Arch_0666	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
Arch_0668	ENOG4105CJN	penicillin-binding protein
Arch_0669	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
Arch_0671	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Arch_0672	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Arch_0674	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
Arch_0675	ENOG4105DFU	Cell wall formation (By similarity)
Arch_0677	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
Arch_0678	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
Arch_0679	ENOG4105VR5	Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA (By similarity)
Arch_0688	ENOG41090R7	Ferric uptake
Arch_0689	ENOG4105CC5	ABC transporter
Arch_0690	ENOG4105DIK	(ABC) transporter
Arch_0691	ENOG4105DSE	periplasmic solute binding protein
Arch_0692	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
Arch_0696	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
Arch_0697	ENOG4105EMA	Periplasmic binding protein LacI transcriptional regulator
Arch_0698	ENOG4105C2J	ABC transporter
Arch_0699	ENOG4107R2W	ABC transporter, permease
Arch_0701	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
Arch_0709	ENOG4105VE1	Phosphatidylcholine synthase
Arch_0714	ENOG4107RTD	sua5 ycio yrdc ywlc family protein
Arch_0718	ENOG4105DAQ	Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) (By similarity)
Arch_0723	ENOG4105EGD	dinuclear metal center protein, YbgI family
Arch_0725	ENOG4107XFJ	UPF0246 protein
Arch_0728	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
Arch_0729	ENOG4105C5F	glutamine synthetase
Arch_0730	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
Arch_0732	ENOG4105C5F	glutamine synthetase
Arch_0738	ENOG4105E0A	ABC, transporter
Arch_0739	ENOG4108U1V	ABC transporter, permease
Arch_0740	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
Arch_0741	ENOG4108HUF	Transporter
Arch_0742	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
Arch_0744	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
Arch_0752	ENOG4107RJF	diphosphate--fructose-6-phosphate 1-phosphotransferase (EC 2.7.1.90)
Arch_0753	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
Arch_0755	ENOG41068KG	domain protein
Arch_0760	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
Arch_0761	ENOG4108JDX	DNA polymerase iii, epsilon subunit
Arch_0763	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Arch_0766	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
Arch_0769	ENOG4107W53	thymidine kinase
Arch_0776	ENOG4107VEG	TrkA-N domain protein
Arch_0780	ENOG4107QMH	DNA methylase
Arch_0781	ENOG4105D8D	Type III
Arch_0782	ENOG4105C0D	helicase
Arch_0791	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
Arch_0796	ENOG4107QM5	aconitate hydratase
Arch_0804	ENOG4105HF0	Membrane
Arch_0809	ENOG4105DSE	periplasmic solute binding protein
Arch_0810	ENOG4105FDK	ABC transporter
Arch_0811	ENOG4105FAV	ABC, transporter
Arch_0812	ENOG4105EJQ	L-serine dehydratase
Arch_0813	ENOG4105C22	threonyL-tRNA synthetase
Arch_0816	ENOG4105E2K	Glycosyl transferase (Group 1
Arch_0819	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
Arch_0820	ENOG4105CDY	transcriptional regulatory protein
Arch_0821	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
Arch_0822	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
Arch_0823	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
Arch_0825	ENOG4107RSV	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Arch_0826	ENOG4107RTU	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA (By similarity)
Arch_0827	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
Arch_0828	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
Arch_0830	ENOG4105C99	atpase involved in dna repair
Arch_0832	ENOG4105CUT	histidyl-tRNA synthetase
Arch_0834	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Arch_0837	ENOG4105C9M	aspartyl-trna synthetase
Arch_0839	ENOG4107R13	MMPL domain protein
Arch_0841	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
Arch_0842	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
Arch_0843	ENOG41080G3	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
Arch_0847	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
Arch_0848	ENOG4105D49	3-dehydroquinate synthase
Arch_0850	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
Arch_0851	ENOG410803B	Involved in the transcription termination process (By similarity)
Arch_0852	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Arch_0853	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
Arch_0854	ENOG4105MTQ	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
Arch_0856	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
Arch_0858	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
Arch_0860	ENOG4105DJV	ribulose-phosphate 3-epimerase
Arch_0861	ENOG4108I05	Binding-protein-dependent transport systems, inner membrane component
Arch_0862	ENOG4107XKF	NMT1 THI5 Like Domain Protein
Arch_0868	ENOG4105Q70	
Arch_0873	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
Arch_0874	ENOG4105CAT	Cytidine monophosphate kinase
Arch_0876	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
Arch_0877	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
Arch_0879	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
Arch_0882	ENOG4105CP7	Triose-phosphate isomerase
Arch_0883	ENOG4105BZA	Phosphoglycerate kinase
Arch_0884	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
Arch_0885	ENOG4105CIE	May be required for sporulation (By similarity)
Arch_0887	ENOG4105C21	Displays ATPase and GTPase activities (By similarity)
Arch_0889	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
Arch_0892	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
Arch_0893	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
Arch_0894	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
Arch_0899	ENOG4105CA9	Pyruvate kinase
Arch_0900	ENOG4107TBN	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
Arch_0902	ENOG4105DVV	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine (By similarity)
Arch_0903	ENOG4105WFD	Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation (By similarity)
Arch_0904	ENOG4105E5F	proteasome
Arch_0905	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
Arch_0909	ENOG4105DWR	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin (By similarity)
Arch_0910	ENOG4105CPC	Aldo Keto reductase
Arch_0913	ENOG4105E2X	shikimate dehydrogenase
Arch_0914	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Arch_0921	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
Arch_0926	ENOG4105DKW	ABC transporter
Arch_0927	ENOG4107QPH	glycogen) synthase
Arch_0929	ENOG4105C5H	ABC transporter
Arch_0931	ENOG4105VG1	fes assembly suf system protein
Arch_0932	ENOG4108UNV	SUF system FeS assembly protein, NifU family
Arch_0933	ENOG4105C9B	Cysteine desulfurase
Arch_0934	ENOG4105C3K	feS assembly ATPase SufC
Arch_0936	ENOG4105JRK	feS assembly protein SufD
Arch_0940	ENOG4105CJR	Integral membrane protein (MviN
Arch_0948	ENOG4105DSU	hydrolase
Arch_0950	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
Arch_0951	ENOG4108K88	Membrane
Arch_0952	ENOG4108DBC	nitroreductase
Arch_0954	ENOG4105C8Y	Acetylornithine aminotransferase
Arch_0956	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
Arch_0957	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
Arch_0960	ENOG4108JQ7	(ABC) transporter
Arch_0961	ENOG4105C3U	ABC transporter
Arch_0964	ENOG4108RWN	rrna methyltransferase
Arch_0965	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
Arch_0966	ENOG41084BS	50S ribosomal protein L35
Arch_0971	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Arch_0972	ENOG4106DBE	Involved in DNA repair and RecF pathway recombination (By similarity)
Arch_0973	ENOG4105CWT	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism (By similarity)
Arch_0975	ENOG4107VNR	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
Arch_0977	ENOG4107TVK	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
Arch_0978	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
Arch_0979	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
Arch_0987	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
Arch_0988	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
Arch_0992	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
Arch_0993	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
Arch_0994	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
Arch_0997	ENOG4105KQC	Competence protein
Arch_0998	ENOG4105D7A	ATP-binding protein
Arch_1000	ENOG4105C8T	Leucyl-tRNA synthetase
Arch_1005	ENOG4105D3A	purine nucleoside phosphorylase DeoD-type
Arch_1006	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
Arch_1007	ENOG4108UMI	ABC transporter, permease
Arch_1008	ENOG4105D01	(LipO)protein
Arch_1010	ENOG4105CK7	Sodium proline symporter
Arch_1011	ENOG4105CG6	trap dicarboxylate transporter dctm subunit
Arch_1012	ENOG41069H7	transport system small permease component
Arch_1013	ENOG4105DR6	Trap dicarboxylate transporter, dctp subunit
Arch_1014	ENOG4108KN7	Removes 5-oxoproline from various penultimate amino acid residues except L-proline (By similarity)
Arch_1018	ENOG4105CRK	lysyL-tRNA synthetase
Arch_1019	ENOG4105CXT	aspartate transcarbamylase
Arch_1020	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
Arch_1022	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
Arch_1023	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
Arch_1025	ENOG4105CD3	dihydroorotase
Arch_1028	ENOG4107S6Z	Na H antiporter
Arch_1029	ENOG4105NRA	50s ribosomal protein l31 type b
Arch_1031	ENOG4105C57	major facilitator superfamily
Arch_1033	ENOG4108680	CrcB-like protein
Arch_1034	ENOG4105WMR	Protein CrcB homolog
Arch_1036	ENOG4105CHH	sulfate transporter
Arch_1041	ENOG410836F	Transposase
Arch_1052	ENOG4107QTH	restriction modification system DNA specificity domain
Arch_1059	ENOG41089UC	methyltransferase, type 11
Arch_1062	ENOG4105E5P	Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation
Arch_1063	ENOG4105CVJ	phosphoglycerate mutase
Arch_1066	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
Arch_1067	ENOG41080RH	Thioredoxin
Arch_1069	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
Arch_1070	ENOG4105K46	50S ribosomal protein l27
Arch_1071	ENOG410826X	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
Arch_1072	ENOG4105C03	ribonuclease
Arch_1073	ENOG4105C4M	(Ubiquinol oxidase) subunit I
Arch_1074	ENOG4105CFY	cytochrome d ubiquinol oxidase, subunit ii
Arch_1075	ENOG4108JJ9	ABC, transporter
Arch_1076	ENOG4108JJ8	(ABC) transporter
Arch_1079	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
Arch_1080	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
Arch_1083	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
Arch_1084	ENOG4106H78	methyltransferase
Arch_1085	ENOG4105CB5	ATP-dependent DNA helicase recG
Arch_1086	ENOG4105VB9	50S ribosomal protein l28
Arch_1087	ENOG4108IPW	abc transporter atp-binding protein
Arch_1088	ENOG4105CM4	permease protein
Arch_1092	ENOG4105CPF	Cell wall formation (By similarity)
Arch_1093	ENOG4105PSQ	Acyl-transferase
Arch_1094	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
Arch_1096	ENOG4105JNK	Glycosyl transferase (Group 1
Arch_1097	ENOG4105DGW	oligopeptidase A
Arch_1099	ENOG4106KRW	Has sphingomyelinase and hemolytic activity. Thought to act as a virulence factor
Arch_1100	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
Arch_1109	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
Arch_1110	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
Arch_1111	ENOG4107R3N	Filamentation induced by cAMP protein fic
Arch_1113	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
Arch_1115	ENOG4105KEN	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
Arch_1119	ENOG4108426	dNA-binding protein
Arch_1120	ENOG4107WGA	YidE YbjL
Arch_1121	ENOG4108SEA	Esterase
Arch_1122	ENOG4105VDH	Dihydroxyacetone kinase
Arch_1123	ENOG4105CMT	Dihydroxyacetone kinase
Arch_1125	ENOG4107RA1	nh(3)-dependent nad( ) synthetase
Arch_1127	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
Arch_1128	ENOG4105C4Y	ABC transporter
Arch_1129	ENOG4105CXY	transporter
Arch_1130	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Arch_1131	ENOG4108TQ9	Histidine kinase
Arch_1132	ENOG4107QT5	Catalyzes the ferrous insertion into protoporphyrin IX (By similarity)
Arch_1140	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
Arch_1141	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
Arch_1143	ENOG4105CC5	ABC transporter
Arch_1144	ENOG4105DIK	(ABC) transporter
Arch_1150	ENOG4105CZV	ABC transporter
Arch_1152	ENOG4105CDA	abc transporter atp-binding protein
Arch_1153	ENOG4105DRP	amino acid AbC transporter
Arch_1154	ENOG4105EAB	amino acid AbC transporter
Arch_1156	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
Arch_1157	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
Arch_1158	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
Arch_1159	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Arch_1160	ENOG4105KT7	mgtC SapB transporter
Arch_1164	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
Arch_1171	ENOG4105CEP	NADH dehydrogenase
Arch_1174	ENOG4105CDH	Citrulline--aspartate ligase
Arch_1175	ENOG4105CH7	arginosuccinase
Arch_1177	ENOG4105C83	adenylosuccinate lyase
Arch_1178	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
Arch_1183	ENOG4108JJB	ABC transporter
Arch_1187	ENOG4107TXC	Transcriptional regulator
Arch_1193	ENOG4105DZW	Dipeptidase
Arch_1217	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
Arch_1218	ENOG4105DR5	peptidase
Arch_1219	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
Arch_1220	ENOG4105CAK	Cell division ATP-binding protein ftsE
Arch_1221	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
Arch_1232	ENOG4105CKW	Inner membrane protein yedI
Arch_1234	ENOG4105C1J	atp-dependent rna helicase
Arch_1235	ENOG41081FY	multiple antibiotic resistance (MarC)-related
Arch_1237	ENOG4107T6F	Xaa-Pro aminopeptidase
Arch_1242	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
Arch_1243	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
Arch_1246	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Arch_1249	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
Arch_1251	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
Arch_1255	ENOG4105QAX	Iron-sulfur
Arch_1256	ENOG4107QY8	reductase
Arch_1263	ENOG4107QSU	Phosphoglucomutase phosphomannomutase alpha beta alpha domain
Arch_1269	ENOG4105UIB	(ABC) transporter
Arch_1270	ENOG4108JQ9	ABC transporter
Arch_1271	ENOG4105DIH	basic membrane
Arch_1272	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
Arch_1275	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
Arch_1276	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
Arch_1278	ENOG4105DWF	phosphomethylpyrimidine kinase
Arch_1279	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
Arch_1281	ENOG4108UW5	maltose o-acetyltransferase
Arch_1286	ENOG4105K5B	UPF0225 protein
Arch_1287	ENOG4105D9Z	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Arch_1289	ENOG4107QP8	phosphohexose isomerase
Arch_1291	ENOG4105CTQ	phosphohexokinase
Arch_1292	ENOG4105CNT	hydrolase family 2
Arch_1296	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
Arch_1297	ENOG4105EXC	Acyl-transferase
Arch_1300	ENOG4108UMN	azlc family
Arch_1307	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
Arch_1310	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
Arch_1314	ENOG4105C34	Pseudouridine synthase
Arch_1315	ENOG4105C6K	Malic enzyme
Arch_1316	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
Arch_1319	ENOG4105C9Q	fumarate hydratase class II
Arch_1320	ENOG4107QVP	Dehydrogenase
Arch_1322	ENOG4108JU3	Alkyl hydroperoxide reductase
Arch_1323	ENOG4105D3R	alkyl hydroperoxide reductase
Arch_1325	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
Arch_1327	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
Arch_1329	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
Arch_1330	ENOG4105E33	succinate dehydrogenase
Arch_1336	ENOG4108097	ATP-binding protein
Arch_1337	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
Arch_1338	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
Arch_1339	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
Arch_1340	ENOG4105CS9	pantothenic acid kinase
Arch_1342	ENOG4108UJD	30S ribosomal protein S9
Arch_1343	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
Arch_1344	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
Arch_1347	ENOG4108ZT0	50S ribosomal protein l17
Arch_1348	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Arch_1350	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
Arch_1351	ENOG41067V7	50S ribosomal protein L36
Arch_1352	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
Arch_1354	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
Arch_1358	ENOG4105C5X	domain protein
Arch_1359	ENOG4105C54	Major Facilitator superfamily
Arch_1361	ENOG4105CEY	Amp-dependent synthetase and ligase
Arch_1363	ENOG4105C1G	acyl-Coa dehydrogenase
Arch_1366	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
Arch_1367	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
Arch_1368	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
Arch_1369	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
Arch_1370	ENOG410849U	50S ribosomal protein L30
Arch_1371	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
Arch_1373	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
Arch_1374	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
Arch_1375	ENOG41082QR	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
Arch_1376	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
Arch_1377	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
Arch_1378	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
Arch_1379	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
Arch_1381	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
Arch_1382	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
Arch_1383	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
Arch_1384	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
Arch_1385	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
Arch_1386	ENOG4105KZR	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
Arch_1387	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
Arch_1388	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
Arch_1389	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
Arch_1390	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
Arch_1391	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
Arch_1392	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
Arch_1393	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
Arch_1395	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Arch_1396	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
Arch_1397	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
Arch_1398	ENOG4108VZM	50s ribosomal protein L10
Arch_1400	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
Arch_1401	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
Arch_1406	ENOG410836F	Transposase
Arch_1411	ENOG4107R4N	Cell wall formation (By similarity)
Arch_1412	ENOG4105WDJ	50S ribosomal protein L33
Arch_1413	ENOG4108VPT	UPF0234 protein
Arch_1415	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
Arch_1418	ENOG4105BZU	Histidine kinase
Arch_1419	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Arch_1424	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
Arch_1426	ENOG4108KGH	TRANSCRIPTIONal
Arch_1427	ENOG4108KGH	TRANSCRIPTIONal
Arch_1429	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Arch_1432	ENOG4107WR6	Maf-like protein
Arch_1434	ENOG4108Z4U	Ferredoxin
Arch_1437	ENOG4105CI3	gtp-binding protein typa
Arch_1439	ENOG4105BZ1	(ABC) transporter
Arch_1440	ENOG4105BZ1	(ABC) transporter
Arch_1445	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
Arch_1446	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
Arch_1447	ENOG4105CEY	Amp-dependent synthetase and ligase
Arch_1448	ENOG4105DFM	M18 family aminopeptidase
Arch_1451	ENOG4105E9K	Isocitrate dehydrogenase
Arch_1453	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
Arch_1457	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
Arch_1459	ENOG4105CID	antiterminator
Arch_1460	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
Arch_1461	ENOG410849S	phosphocarrier protein (HPr)
Arch_1462	ENOG4108YYH	Nadph-dependent fmn reductase
Arch_1469	ENOG4105KJP	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
Arch_1470	ENOG4105CRE	cytochrome C
Arch_1471	ENOG4105EBH	Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment (By similarity)
Arch_1472	ENOG4107QIV	Cytochrome c biogenesis protein
Arch_1474	ENOG4105EAU	Plays a role in nitrite reduction (By similarity)
Arch_1476	ENOG4107YVI	ribose 5-phosphate isomerase
Arch_1477	ENOG4107R0P	L-ribulose-5-phosphate 4-epimerase
Arch_1478	ENOG4105ETE	Transcriptional regulator (LacI family
Arch_1480	ENOG4108VCA	G U mismatch-specific DNA glycosylase
Arch_1485	ENOG4105C8J	)-transporter
Arch_1486	ENOG4105CJ1	ABC, transporter
Arch_1487	ENOG4105CBG	Sulfatase
Arch_1488	ENOG4105WBN	Transcriptional regulator (LacI family
Arch_1489	ENOG4105C54	Major Facilitator superfamily
Arch_1490	ENOG4105C4X	radical SAM domain protein
Arch_1494	ENOG4105C3G	gtp-binding protein
Arch_1499	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
Arch_1501	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
Arch_1502	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
Arch_1503	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
Arch_1505	ENOG4107YD5	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
Arch_1506	ENOG4108HW8	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
Arch_1507	ENOG4108V1T	peptidylprolyl cis-trans isomerase
Arch_1516	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
Arch_1518	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
Arch_1519	ENOG4107XT7	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
Arch_1520	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
Arch_1521	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
Arch_1522	ENOG4108XG4	DNA-binding transcriptional regulator
Arch_1523	ENOG4108IUX	(ABC) transporter
Arch_1524	ENOG4105RHA	ABC transporter, permease
Arch_1549	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
Arch_1550	ENOG4105EFC	phage portal protein HK97 family
Arch_1551	ENOG4105KBH	arsR family transcriptional regulator
Arch_1575	ENOG4108JJB	ABC transporter
Arch_1582	ENOG4107QMH	DNA methylase
Arch_1586	ENOG4105C5H	ABC transporter
Arch_1587	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
Arch_1588	ENOG4105CI1	PTS System
Arch_1591	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
Arch_1593	ENOG4105F8V	Hydrolase, tatD family
Arch_1594	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
Arch_1595	ENOG4108RWI	nicotinamidase
Arch_1596	ENOG4108ZMX	Domain of unknown function (DU1801)
Arch_1601	ENOG4108M15	ABC transporter
Arch_1603	ENOG4105BZU	Histidine kinase
Arch_1604	ENOG4108S01	response regulator
Arch_1605	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
Arch_1610	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
Arch_1612	ENOG41080FJ	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
Arch_1615	ENOG4105C72	UPF0176 protein
Arch_1619	ENOG4105C7N	Xanthine uracil vitamin C permease
Arch_1620	ENOG4105EIP	mannose-6-phosphate isomerase
Arch_1622	ENOG4105VEQ	Cold shock protein
Arch_1624	ENOG41087YS	Phage shock protein A
Arch_1626	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Arch_1627	ENOG4105BZU	Histidine kinase
Arch_1631	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
Arch_1634	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
Arch_1636	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
Arch_1637	ENOG4105CPQ	Dehydrogenase
Arch_1638	ENOG4105CZN	Potassium uptake protein
Arch_1643	ENOG4108IJ9	(ABC) transporter
Arch_1645	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
Arch_1655	ENOG4105C2W	permease
Arch_1659	ENOG4105C8N	cysteinyl-tRNA synthetase
Arch_1661	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
Arch_1662	ENOG4105CE5	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) (By similarity)
Arch_1663	ENOG4108VJ1	Transcriptional regulator (CarD family
Arch_1664	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
Arch_1667	ENOG4107RPC	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
Arch_1670	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
Arch_1675	ENOG4105KBH	arsR family transcriptional regulator
Arch_1679	ENOG4107QJE	Chromosome Partitioning Protein
Arch_1685	ENOG4105MU5	relaxase mobilization nuclease domain protein
Arch_1693	ENOG4105E4C	Lytic transglycosylase catalytic
Arch_1703	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
Arch_1704	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
Arch_1705	ENOG4105C76	Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue (By similarity)
Arch_1708	ENOG4108I5C	dEAD DEAH box helicase
Arch_1719	ENOG4105D74	hydrolase
Arch_1722	ENOG4105IJJ	transcriptional regulator, crp fnr family
Arch_1727	ENOG4105BZ4	penicillin-binding protein
Arch_1729	ENOG4108RVA	ribokinase
Arch_1731	ENOG4105EDR	glucose galactose transporter
Arch_1739	ENOG4105DPH	UPF0371 protein
Arch_1744	ENOG4108Z6B	deaminase
Arch_1745	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
Arch_1748	ENOG4105C3Q	Glycosyl transferase, family 2
Arch_1752	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
Arch_1753	ENOG410667J	hydrolase
Arch_1756	ENOG4108VWQ	crispr-associated protein
Arch_1770	ENOG4105CXY	transporter
Arch_1771	ENOG4105C8P	)-transporter
Arch_1772	ENOG4105ESP	cell wall surface anchor family protein
Arch_1774	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
Arch_1775	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
Arch_1776	ENOG4107SFS	Catalyzes the formation of 5-methyl-uridine at position 747 (m5U747) in 23S rRNA (By similarity)
Arch_1783	ENOG4105CQ7	ATP-dependent helicase
Arch_1786	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
Arch_1790	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
Arch_1794	ENOG4105CDU	Replicative dna helicase
Arch_1799	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
Arch_1800	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
Arch_1801	ENOG4107YH6	single-stranded DNA-binding protein
Arch_1802	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
Arch_1803	ENOG4105BZ4	penicillin-binding protein
Arch_1804	ENOG4105DSF	transport protein
Arch_1806	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
Arch_1810	ENOG4105C3M	thioredoxin reductase
Arch_1814	ENOG4107QJE	Chromosome Partitioning Protein
Arch_1815	ENOG4107XUG	Specifically methylates the N7 position of a guanine in 16S rRNA (By similarity)
Arch_1816	ENOG410836F	Transposase
Arch_1818	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
Arch_1819	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
Arch_1820	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
Arch_1821	ENOG41084CH	50S ribosomal protein l34