locus-tag	class	description
NG665_00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
NG665_00010	COG0592	DNA-directed DNA polymerase activity
NG665_00015	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
NG665_00025	COG0187	DNA topoisomerase II activity
NG665_00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NG665_00055	COG3250	beta-galactosidase activity
NG665_00065	COG1309	transcriptional regulator
NG665_00070	COG1511	domain protein
NG665_00080	COG1620	l-lactate permease
NG665_00085	COG0247	lactate metabolic process
NG665_00090	COG1139	Iron-sulfur cluster binding protein
NG665_00095	COG1556	Lactate utilization protein
NG665_00100	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NG665_00140	COG0601	transmembrane transport
NG665_00145	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NG665_00180	COG0584	glycerophosphoryl diester phosphodiesterase
NG665_00185	COG1088	dTDP-glucose 4,6-dehydratase activity
NG665_00210	COG3754	Rhamnan synthesis protein F
NG665_00235	COG0463	Glycosyl transferase, family 2
NG665_00245	COG2244	polysaccharide biosynthetic process
NG665_00255	COG3475	LICD family
NG665_00260	COG4750	Nucleotidyl transferase
NG665_00270	COG1091	dTDP-4-dehydrorhamnose reductase activity
NG665_00280	COG1216	Glycosyl transferase, family 2
NG665_00280	COG1442	glycosyl transferase family 8
NG665_00285	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
NG665_00310	COG0705	Rhomboid family
NG665_00320	COG3764	Sortase (surface protein transpeptidase)
NG665_00335	COG0768	penicillin binding
NG665_00345	COG0631	protein serine/threonine phosphatase activity
NG665_00345	COG3266	domain, Protein
NG665_00350	COG1716	ATPase activity
NG665_00355	COG1716	ATPase activity
NG665_00355	COG0842	Transport permease protein
NG665_00355	COG1131	(ABC) transporter
NG665_00375	COG3764	Sortase (surface protein transpeptidase)
NG665_00380	COG2860	membrane
NG665_00390	COG0328	RNA-DNA hybrid ribonuclease activity
NG665_00400	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
NG665_00405	COG1854	S-ribosylhomocysteine lyase activity
NG665_00415	COG1780	Probably involved in ribonucleotide reductase function
NG665_00420	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NG665_00430	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NG665_00435	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NG665_00460	COG0765	amino acid transport
NG665_00470	COG1643	Atp-dependent helicase
NG665_00525	COG2188	Transcriptional regulator
NG665_00555	COG0586	Pfam SNARE associated Golgi protein
NG665_00560	COG1950	PFAM Membrane protein of
NG665_00580	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
NG665_00585	COG0803	Belongs to the bacterial solute-binding protein 9 family
NG665_00590	COG1121	(ABC) transporter
NG665_00595	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NG665_00600	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NG665_00605	COG1321	iron dependent repressor
NG665_00610	COG0717	Belongs to the dCTP deaminase family
NG665_00615	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
NG665_00615	COG2111	Na H antiporter
NG665_00620	COG1006	Multisubunit Na H antiporter MnhC subunit
NG665_00625	COG0651	ATP synthesis coupled electron transport
NG665_00630	COG1863	multisubunit Na H antiporter MnhE subunit
NG665_00640	COG1320	monovalent cation:proton antiporter activity
NG665_00655	COG4149	molybdate abc transporter
NG665_00660	COG3842	ATPase activity
NG665_00685	COG1505	serine-type exopeptidase activity
NG665_00690	COG0443	Heat shock 70 kDa protein
NG665_00695	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
NG665_00700	COG0484	heat shock protein binding
NG665_00710	COG0494	nUDIX hydrolase
NG665_00740	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NG665_00755	COG1113	amino acid transport
NG665_00760	COG1260	myo-inositol-1-phosphate synthase
NG665_00775	COG0300	oxidoreductase activity
NG665_00780	COG0494	nUDIX hydrolase
NG665_00810	COG0191	fructose-bisphosphate aldolase activity
NG665_00855	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
NG665_00860	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
NG665_00865	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NG665_00935	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NG665_00955	COG0306	phosphate transporter
NG665_00965	COG1115	amino acid carrier protein
NG665_00975	COG4044	May play a role in the intracellular transport of hydrophobic ligands
NG665_00985	COG1490	D-aminoacyl-tRNA deacylase activity
NG665_00995	COG0133	tryptophan synthase activity
NG665_01000	COG2056	Na+-H+ antiporter family
NG665_01005	COG0574	Belongs to the PEP-utilizing enzyme family
NG665_01005	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NG665_01010	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
NG665_01010	COG2755	lipolytic protein G-D-S-L family
NG665_01035	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NG665_01040	COG2027	D-alanyl-D-alanine carboxypeptidase
NG665_01050	COG0037	tRNA processing
NG665_01055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NG665_01060	COG0302	gtp cyclohydrolase
NG665_01065	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
NG665_01070	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NG665_01095	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
NG665_01105	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NG665_01115	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
NG665_01120	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NG665_01130	COG0247	lactate metabolic process
NG665_01140	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
NG665_01150	COG1194	a g-specific adenine glycosylase
NG665_01165	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
NG665_01170	COG0569	domain protein
NG665_01175	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NG665_01195	COG0406	alpha-ribazole phosphatase activity
NG665_01205	COG1575	Belongs to the MenA family. Type 1 subfamily
NG665_01215	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
NG665_01220	COG4948	Mandelate Racemase Muconate Lactonizing
NG665_01225	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NG665_01230	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
NG665_01235	COG1169	isochorismate synthase
NG665_01240	COG2226	methyltransferase
NG665_01245	COG0644	oxidoreductase
NG665_01255	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NG665_01260	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
NG665_01265	COG0649	NAD binding
NG665_01275	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
NG665_01280	COG1034	ATP synthesis coupled electron transport
NG665_01285	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
NG665_01295	COG0839	Belongs to the complex I subunit 6 family
NG665_01300	COG0713	ATP synthesis coupled electron transport
NG665_01315	COG1007	ATP synthesis coupled electron transport
NG665_01320	COG0142	geranyltranstransferase activity
NG665_01325	COG0653	protein targeting
NG665_01365	COG0419	ATPase involved in DNA repair
NG665_01370	COG0420	3'-5' exonuclease activity
NG665_01390	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NG665_01405	COG1162	GTPase activity
NG665_01410	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
NG665_01420	COG2188	Transcriptional regulator
NG665_01430	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NG665_01435	COG0363	glucosamine-6-phosphate deaminase activity
NG665_01440	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
NG665_01445	COG1595	DNA-templated transcription, initiation
NG665_01505	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
NG665_01510	COG1120	ATPase activity
NG665_01525	COG1253	flavin adenine dinucleotide binding
NG665_01535	COG0739	heme binding
NG665_01540	COG0584	glycerophosphoryl diester phosphodiesterase
NG665_01575	COG0018	arginyl-trna synthetase
NG665_01590	COG0254	rRNA binding
NG665_01595	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
NG665_01600	COG2890	protein-(glutamine-N5) methyltransferase activity
NG665_01620	COG0356	it plays a direct role in the translocation of protons across the membrane
NG665_01625	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NG665_01630	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
NG665_01635	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
NG665_01640	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
NG665_01645	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
NG665_01650	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
NG665_01665	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
NG665_01710	COG1175	transmembrane transport
NG665_01715	COG3833	ABC-type maltose transport systems, permease component
NG665_01720	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
NG665_01730	COG0366	Alpha amylase catalytic
NG665_01735	COG0366	Alpha amylase catalytic
NG665_01745	COG0058	SHG alpha-glucan phosphorylase activity
NG665_01750	COG0180	Tryptophanyl-tRNA synthetase
NG665_01755	COG0577	efflux transmembrane transporter activity
NG665_01755	COG1136	(ABC) transporter
NG665_01835	COG2816	NAD+ diphosphatase activity
NG665_01855	COG3480	Lon protease (S16) C-terminal proteolytic domain
NG665_01865	COG1615	UPF0182 protein
NG665_01875	COG1131	(ABC) transporter
NG665_01880	COG2188	Transcriptional regulator
NG665_01900	COG3619	membrane
NG665_01915	COG1136	(ABC) transporter
NG665_01935	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
NG665_01960	COG1136	(ABC) transporter
NG665_01960	COG0577	efflux transmembrane transporter activity
NG665_01965	COG2197	response regulator
NG665_01975	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
NG665_01980	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NG665_01985	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NG665_01990	COG0154	amidase activity
NG665_01995	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
NG665_02030	COG2985	domain, Protein
NG665_02030	COG0569	domain protein
NG665_02040	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NG665_02045	COG1882	Formate acetyltransferase
NG665_02075	COG0577	efflux transmembrane transporter activity
NG665_02075	COG1136	(ABC) transporter
NG665_02080	COG0577	efflux transmembrane transporter activity
NG665_02125	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
NG665_02140	COG1160	GTP binding
NG665_02175	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NG665_02180	COG2116	formate transmembrane transporter activity
NG665_02195	COG3590	peptidase
NG665_02205	COG1045	serine acetyltransferase
NG665_02215	COG1739	Uncharacterized protein family UPF0029
NG665_02235	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NG665_02240	COG1121	(ABC) transporter
NG665_02255	COG1966	Carbon starvation protein
NG665_02280	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NG665_02285	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
NG665_02290	COG0471	metal ion transport
NG665_02300	COG1428	Deoxynucleoside kinase
NG665_02305	COG2217	Heavy metal translocating P-type atpase
NG665_02325	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NG665_02335	COG3409	Peptidoglycan-binding domain 1 protein
NG665_02415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NG665_02415	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
NG665_02425	COG3617	BRO family, N-terminal domain
NG665_02475	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NG665_02500	COG1802	Transcriptional regulator
NG665_02500	COG4626	Terminase
NG665_02510	COG4695	Portal protein
NG665_02515	COG0740	serine-type endopeptidase activity
NG665_02635	COG1136	(ABC) transporter
NG665_02645	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
NG665_02660	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NG665_02665	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NG665_02670	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NG665_02675	COG0267	Belongs to the bacterial ribosomal protein bL33 family
NG665_02700	COG0544	peptidyl-prolyl cis-trans isomerase activity
NG665_02705	COG0740	serine-type endopeptidase activity
NG665_02710	COG0740	serine-type endopeptidase activity
NG665_02715	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
NG665_02720	COG1022	Amp-dependent synthetase and ligase
NG665_02730	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NG665_02740	COG1132	(ABC) transporter
NG665_02745	COG1132	(ABC) transporter
NG665_02755	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
NG665_02760	COG0285	dihydrofolate synthase activity
NG665_02770	COG1461	Dihydroxyacetone kinase
NG665_02775	COG1196	nuclear chromosome segregation
NG665_02810	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
NG665_02820	COG1837	Belongs to the UPF0109 family
NG665_02825	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
NG665_02830	COG0336	Belongs to the RNA methyltransferase TrmD family
NG665_02835	COG0335	large ribosomal subunit rRNA binding
NG665_02845	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NG665_02870	COG4974	Belongs to the 'phage' integrase family
NG665_02880	COG0052	Belongs to the universal ribosomal protein uS2 family
NG665_02885	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
NG665_02890	COG1609	Transcriptional regulator
NG665_02920	COG4626	Terminase
NG665_02920	COG1802	Transcriptional regulator
NG665_02965	COG0644	oxidoreductase
NG665_02975	COG0477	Major facilitator Superfamily
NG665_02990	COG0233	cytoplasmic translational termination
NG665_02995	COG0575	Belongs to the CDS family
NG665_03000	COG0820	rRNA (adenine-C2-)-methyltransferase activity
NG665_03015	COG0750	zinc metalloprotease
NG665_03020	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
NG665_03030	COG0442	prolyl-tRNA aminoacylation
NG665_03040	COG0779	Required for maturation of 30S ribosomal subunits
NG665_03055	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
NG665_03060	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
NG665_03065	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
NG665_03110	COG1136	(ABC) transporter
NG665_03110	COG0577	efflux transmembrane transporter activity
NG665_03115	COG1136	(ABC) transporter
NG665_03115	COG0577	efflux transmembrane transporter activity
NG665_03130	COG1131	(ABC) transporter
NG665_03140	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
NG665_03145	COG1185	polyribonucleotide nucleotidyltransferase activity
NG665_03155	COG0612	Peptidase, M16
NG665_03170	COG3842	ATPase activity
NG665_03195	COG1116	anion transmembrane transporter activity
NG665_03230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NG665_03235	COG1674	ftsk spoiiie
NG665_03245	COG1058	Belongs to the CinA family
NG665_03245	COG1546	Belongs to the CinA family
NG665_03250	COG1396	sequence-specific DNA binding
NG665_03270	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
NG665_03275	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
NG665_03285	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NG665_03295	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
NG665_03305	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NG665_03310	COG0318	PFAM AMP-dependent synthetase and ligase
NG665_03330	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NG665_03340	COG2001	Belongs to the MraZ family
NG665_03345	COG0275	rRNA processing
NG665_03355	COG0768	penicillin binding
NG665_03360	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NG665_03370	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NG665_03375	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
NG665_03380	COG0772	Belongs to the SEDS family
NG665_03390	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
NG665_03400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NG665_03410	COG1799	cell septum assembly
NG665_03460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NG665_03465	COG1121	(ABC) transporter
NG665_03470	COG0803	Belongs to the bacterial solute-binding protein 9 family
NG665_03470	COG3443	Belongs to the bacterial solute-binding protein 9 family
NG665_03475	COG0423	glycine-tRNA ligase activity
NG665_03495	COG1879	ABC-type sugar transport system periplasmic component
NG665_03500	COG1129	ABC transporter
NG665_03505	COG4211	Belongs to the binding-protein-dependent transport system permease family
NG665_03525	COG0358	DNA primase activity
NG665_03605	COG0009	L-threonylcarbamoyladenylate synthase
NG665_03625	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
NG665_03650	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
NG665_03655	COG2353	YceI-like domain
NG665_03670	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NG665_03680	COG3022	response to hydroperoxide
NG665_03705	COG0174	glutamine synthetase
NG665_03710	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
NG665_03720	COG0174	glutamine synthetase
NG665_03740	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NG665_03750	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
NG665_03800	COG0205	6-phosphofructokinase activity
NG665_03805	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
NG665_03810	COG0515	serine threonine protein kinase
NG665_03810	COG2815	serine threonine protein kinase
NG665_03835	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NG665_03840	COG2176	DNA-directed DNA polymerase activity
NG665_03850	COG0187	DNA topoisomerase II activity
NG665_03865	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NG665_03880	COG1435	thymidine kinase activity
NG665_03915	COG0569	domain protein
NG665_03925	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NG665_03930	COG0300	oxidoreductase activity
NG665_03935	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NG665_03945	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
NG665_03950	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
NG665_03955	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
NG665_03965	COG0138	bifunctional purine biosynthesis protein purh
NG665_03970	COG0151	Belongs to the GarS family
NG665_03975	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NG665_03980	COG2759	Belongs to the formate--tetrahydrofolate ligase family
NG665_03990	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
NG665_04060	COG1760	l-serine dehydratase
NG665_04065	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
NG665_04070	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NG665_04075	COG1560	Kdo2-lipid A biosynthetic process
NG665_04095	COG1051	belongs to the nudix hydrolase family
NG665_04100	COG0217	transcriptional regulatory protein
NG665_04105	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
NG665_04110	COG0632	four-way junction helicase activity
NG665_04115	COG2255	four-way junction helicase activity
NG665_04125	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NG665_04130	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
NG665_04135	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
NG665_04140	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NG665_04150	COG1196	nuclear chromosome segregation
NG665_04160	COG0124	histidyl-tRNA synthetase
NG665_04170	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NG665_04185	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
NG665_04190	COG1376	ErfK ybiS ycfS ynhG family protein
NG665_04200	COG2409	Drug exporters of the RND superfamily
NG665_04210	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
NG665_04215	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
NG665_04220	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
NG665_04240	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
NG665_04250	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
NG665_04255	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
NG665_04260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
NG665_04265	COG0194	GDP metabolic process
NG665_04270	COG1758	RNA polymerase activity
NG665_04280	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
NG665_04290	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
NG665_04300	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NG665_04305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NG665_04310	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
NG665_04355	COG1716	ATPase activity
NG665_04385	COG1160	GTP binding
NG665_04390	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
NG665_04400	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NG665_04405	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NG665_04425	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NG665_04430	COG0149	triose-phosphate isomerase activity
NG665_04435	COG0126	phosphoglycerate kinase activity
NG665_04440	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
NG665_04445	COG1481	regulation of sporulation
NG665_04450	COG1660	Displays ATPase and GTPase activities
NG665_04455	COG0322	excinuclease ABC activity
NG665_04480	COG0556	nucleotide-excision repair
NG665_04485	COG2814	Major facilitator Superfamily
NG665_04490	COG0237	dephospho-CoA kinase activity
NG665_04490	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
NG665_04495	COG0539	negative regulation of cytoplasmic translation
NG665_04500	COG2226	methyltransferase
NG665_04525	COG0469	pyruvate kinase activity
NG665_04530	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
NG665_04540	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
NG665_04550	COG4122	O-methyltransferase activity
NG665_04555	COG1222	aaa ATPase
NG665_04575	COG1968	undecaprenyl-diphosphatase activity
NG665_04580	COG0667	Aldo Keto reductase
NG665_04590	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NG665_04615	COG0587	DNA-directed DNA polymerase activity
NG665_04630	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NG665_04655	COG1119	ATPase activity
NG665_04660	COG0297	glycogen (starch) synthase activity
NG665_04675	COG0488	(ABC) transporter
NG665_04680	COG2151	metal-sulfur cluster biosynthetic enzyme
NG665_04685	COG0822	iron-sulfur transferase activity
NG665_04695	COG0396	ATPase activity
NG665_04705	COG0719	Fe-S assembly protein
NG665_04720	COG0494	nUDIX hydrolase
NG665_04745	COG0497	DNA recombination
NG665_04750	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
NG665_04765	COG0647	UMP catabolic process
NG665_04805	COG1022	Amp-dependent synthetase and ligase
NG665_04810	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
NG665_04815	COG3949	Membrane
NG665_04820	COG0778	Nitroreductase
NG665_04825	COG1438	arginine binding
NG665_04830	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
NG665_04835	COG0300	oxidoreductase activity
NG665_04855	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NG665_04860	COG4608	Belongs to the ABC transporter superfamily
NG665_04865	COG0444	Belongs to the ABC transporter superfamily
NG665_04880	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NG665_04885	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
NG665_04890	COG0291	Belongs to the bacterial ribosomal protein bL35 family
NG665_04915	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NG665_04920	COG1381	Involved in DNA repair and RecF pathway recombination
NG665_04925	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
NG665_04935	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
NG665_04945	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NG665_04950	COG0484	heat shock protein binding
NG665_04955	COG1420	regulation of RNA biosynthetic process
NG665_04975	COG0220	tRNA (guanine-N7-)-methyltransferase activity
NG665_04980	COG0481	GTPase activity
NG665_05000	COG0268	Binds directly to 16S ribosomal RNA
NG665_05015	COG1555	photosystem II stabilization
NG665_05015	COG1596	polysaccharide export
NG665_05020	COG0433	COG0433 Predicted ATPase
NG665_05035	COG0495	leucyl-tRNA aminoacylation
NG665_05040	COG0537	adenosine 5'-monophosphoramidase activity
NG665_05060	COG0813	purine-nucleoside phosphorylase activity
NG665_05065	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
NG665_05070	COG2011	ABC-type metal ion transport system permease component
NG665_05080	COG1012	belongs to the aldehyde dehydrogenase family
NG665_05085	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NG665_05090	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NG665_05120	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
NG665_05125	COG0284	orotidine-5'-phosphate decarboxylase activity
NG665_05130	COG0167	dihydroorotate dehydrogenase activity
NG665_05135	COG0543	2 iron, 2 sulfur cluster binding
NG665_05145	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NG665_05155	COG1757	Na H antiporter
NG665_05160	COG0254	rRNA binding
NG665_05170	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NG665_05175	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
NG665_05220	COG1125	glycine betaine transport
NG665_05220	COG0517	IMP dehydrogenase activity
NG665_05225	COG1732	Glycine betaine
NG665_05230	COG0659	secondary active sulfate transmembrane transporter activity
NG665_05240	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NG665_05245	COG0765	amino acid transport
NG665_05255	COG1126	abc transporter atp-binding protein
NG665_05265	COG1162	GTPase activity
NG665_05270	COG4695	Portal protein
NG665_05370	COG0799	negative regulation of ribosome biogenesis
NG665_05380	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NG665_05385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
NG665_05395	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
NG665_05400	COG0211	Belongs to the bacterial ribosomal protein bL27 family
NG665_05405	COG0261	This protein binds to 23S rRNA in the presence of protein L20
NG665_05410	COG1530	ribonuclease E activity
NG665_05415	COG1271	oxidase subunit
NG665_05420	COG1294	oxidase, subunit
NG665_05425	COG4988	ABC transporter
NG665_05430	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
NG665_05450	COG0571	ribonuclease III activity
NG665_05465	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
NG665_05470	COG0742	ribosomal rna small subunit methyltransferase
NG665_05475	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
NG665_05480	COG0227	Belongs to the bacterial ribosomal protein bL28 family
NG665_05490	COG1181	Belongs to the D-alanine--D-alanine ligase family
NG665_05495	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NG665_05505	COG0438	transferase activity, transferring glycosyl groups
NG665_05510	COG0339	signal peptide processing
NG665_05530	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
NG665_05585	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
NG665_05590	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
NG665_05615	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
NG665_05625	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
NG665_05650	COG0569	domain protein
NG665_05650	COG2985	domain, Protein
NG665_05655	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NG665_05665	COG2376	Dihydroxyacetone kinase
NG665_05695	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
NG665_05700	COG0028	Belongs to the TPP enzyme family
NG665_05715	COG1619	proteins homologs of microcin C7 resistance protein MccF
NG665_05735	COG1595	DNA-templated transcription, initiation
NG665_05760	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
NG665_05770	COG1418	mRNA catabolic process
NG665_05775	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NG665_05780	COG1121	(ABC) transporter
NG665_05795	COG1725	Transcriptional regulator
NG665_05800	COG1131	(ABC) transporter
NG665_05810	COG1126	abc transporter atp-binding protein
NG665_05815	COG0765	amino acid transport
NG665_05820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NG665_05825	COG1114	Component of the transport system for branched-chain amino acids
NG665_05840	COG1131	(ABC) transporter
NG665_05845	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NG665_05855	COG0730	response to heat
NG665_05865	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NG665_05870	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
NG665_05875	COG0516	GMP reductase activity
NG665_05875	COG0517	IMP dehydrogenase activity
NG665_05890	COG1230	cation diffusion facilitator family transporter
NG665_05900	COG0789	Transcriptional regulator
NG665_05915	COG1132	(ABC) transporter
NG665_05920	COG2375	cellular response to nickel ion
NG665_05920	COG1132	(ABC) transporter
NG665_05925	COG1129	ABC transporter
NG665_05940	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
NG665_05960	COG0745	RESPONSE REGULATOR receiver
NG665_05965	COG5002	protein histidine kinase activity
NG665_05970	COG0704	Plays a role in the regulation of phosphate uptake
NG665_05975	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NG665_05985	COG1397	ADP-ribosylglycohydrolase
NG665_05990	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NG665_06030	COG0739	heme binding
NG665_06035	COG2177	Part of the ABC transporter FtsEX involved in
NG665_06040	COG2884	Cell division ATP-binding protein ftsE
NG665_06045	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NG665_06100	COG2354	Protein conserved in bacteria
NG665_06115	COG2095	MarC family integral membrane protein
NG665_06125	COG0006	proline dipeptidase activity
NG665_06160	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
NG665_06185	COG1079	Belongs to the binding-protein-dependent transport system permease family
NG665_06190	COG4603	Belongs to the binding-protein-dependent transport system permease family
NG665_06195	COG3845	ABC transporter
NG665_06200	COG1744	ABC transporter substrate-binding protein PnrA-like
NG665_06220	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
NG665_06225	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
NG665_06230	COG0110	maltose O-acetyltransferase activity
NG665_06240	COG2197	response regulator
NG665_06260	COG0039	L-malate dehydrogenase activity
NG665_06265	COG0166	Belongs to the GPI family
NG665_06275	COG0205	6-phosphofructokinase activity
NG665_06300	COG0045	succinate-CoA ligase (ADP-forming) activity
NG665_06320	COG0789	Transcriptional regulator
NG665_06325	COG2814	Major facilitator Superfamily
NG665_06380	COG0395	ABC-type sugar transport system, permease component
NG665_06385	COG1175	transmembrane transport
NG665_06395	COG1501	Belongs to the glycosyl hydrolase 31 family
NG665_06400	COG2115	Belongs to the xylose isomerase family
NG665_06405	COG1070	Carbohydrate kinase
NG665_06420	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
NG665_06420	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
NG665_06445	COG2801	Transposase and inactivated derivatives
NG665_06460	COG2801	Transposase and inactivated derivatives
NG665_06485	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NG665_06495	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NG665_06500	COG0518	GMP synthase (glutamine-hydrolyzing) activity
NG665_06500	COG0519	Catalyzes the synthesis of GMP from XMP
NG665_06515	COG0280	phosphate acetyltransferase
NG665_06515	COG0857	belongs to the CobB CobQ family
NG665_06520	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NG665_06535	COG0114	fumarate hydratase activity
NG665_06540	COG0516	GMP reductase activity
NG665_06560	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
NG665_06575	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
NG665_06580	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
NG665_06585	COG1053	succinate dehydrogenase
NG665_06595	COG0456	acetyltransferase
NG665_06600	COG0456	acetyltransferase
NG665_06600	COG1214	PFAM Peptidase M22, glycoprotease
NG665_06610	COG0802	atpase or kinase
NG665_06615	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NG665_06620	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
NG665_06620	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
NG665_06625	COG1072	(Pantothenic acid kinase))
NG665_06635	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
NG665_06640	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
NG665_06645	COG0101	tRNA pseudouridine synthase activity
NG665_06650	COG1940	carbohydrate kinase activity
NG665_06655	COG0203	ribosomal protein L17
NG665_06660	COG0202	RNA polymerase activity
NG665_06670	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
NG665_06675	COG0257	Belongs to the bacterial ribosomal protein bL36 family
NG665_06680	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
NG665_06685	COG0024	Methionine aminopeptidase
NG665_06690	COG0563	adenylate kinase activity
NG665_06695	COG0201	protein transport
NG665_06700	COG0200	Binds to the 23S rRNA
NG665_06705	COG1841	ribosomal large subunit assembly
NG665_06710	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
NG665_06720	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
NG665_06725	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
NG665_06730	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
NG665_06735	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
NG665_06740	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
NG665_06745	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
NG665_06760	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
NG665_06765	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
NG665_06770	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
NG665_06775	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
NG665_06780	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
NG665_06785	COG0089	rRNA binding
NG665_06790	COG0088	Forms part of the polypeptide exit tunnel
NG665_06795	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
NG665_06800	COG0051	transcription antitermination factor activity, RNA binding
NG665_06805	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
NG665_06810	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
NG665_06815	COG0049	tRNA binding
NG665_06820	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
NG665_06825	COG0840	transmembrane signaling receptor activity
NG665_06830	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
NG665_06835	COG0085	RNA polymerase activity
NG665_06840	COG0222	ribosome binding
NG665_06845	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
NG665_06850	COG0572	uridine kinase
NG665_06855	COG0081	regulation of translation
NG665_06860	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
NG665_06880	COG0436	Aminotransferase
NG665_06895	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
NG665_06910	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NG665_06940	COG1666	GTP binding
NG665_06955	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NG665_06970	COG5002	protein histidine kinase activity
NG665_06975	COG0745	RESPONSE REGULATOR receiver
NG665_07010	COG1316	TRANSCRIPTIONal
NG665_07015	COG1316	TRANSCRIPTIONal
NG665_07020	COG0642	Histidine kinase
NG665_07040	COG0424	maF-like protein
NG665_07065	COG1217	gtp-binding protein TYPA
NG665_07075	COG1132	(ABC) transporter
NG665_07080	COG1132	(ABC) transporter
NG665_07105	COG0321	lipoyl(octanoyl) transferase activity
NG665_07110	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
NG665_07115	COG0318	PFAM AMP-dependent synthetase and ligase
NG665_07120	COG1362	aminopeptidase activity
NG665_07135	COG2838	Isocitrate dehydrogenase
NG665_07145	COG0039	L-malate dehydrogenase activity
NG665_07150	COG3971	2-oxopent-4-enoate hydratase activity
NG665_07165	COG2195	Cleaves the N-terminal amino acid of tripeptides
NG665_07185	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NG665_07190	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
NG665_07210	COG0431	NADPH-dependent FMN reductase
NG665_07220	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NG665_07240	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
NG665_07260	COG2357	RelA SpoT domain protein
NG665_07275	COG3177	Filamentation induced by cAMP protein fic
NG665_07295	COG0733	neurotransmitter:sodium symporter activity
NG665_07310	COG0366	Alpha amylase catalytic
NG665_07345	COG4115	mRNA cleavage
NG665_07350	COG2161	toxin-antitoxin pair type II binding
NG665_07355	COG0012	GTP binding
NG665_07360	COG1322	Protein conserved in bacteria
NG665_07365	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
NG665_07375	COG1722	exodeoxyribonuclease VII activity
NG665_07385	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
NG665_07395	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NG665_07400	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
NG665_07415	COG1131	(ABC) transporter
NG665_07430	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NG665_07450	COG0148	phosphopyruvate hydratase activity
NG665_07460	COG0193	aminoacyl-tRNA hydrolase activity
NG665_07465	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
NG665_07475	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NG665_07485	COG1309	transcriptional regulator
NG665_07490	COG4152	abc transporter atp-binding protein
NG665_07495	COG1668	transmembrane transport
NG665_07510	COG0488	(ABC) transporter
NG665_07515	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
NG665_07520	COG2190	(PTS) system
NG665_07525	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NG665_07525	COG1263	PTS System
NG665_07530	COG3711	transcriptional antiterminator
NG665_07535	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
NG665_07545	COG0084	hydrolase, TatD family'
NG665_07550	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
NG665_07555	COG1335	isochorismatase
NG665_07560	COG2409	Drug exporters of the RND superfamily
NG665_07575	COG1131	(ABC) transporter
NG665_07585	COG4585	Histidine kinase
NG665_07590	COG2197	response regulator
NG665_07620	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NG665_07630	COG1970	mechanosensitive ion channel activity
NG665_07645	COG1054	Belongs to the UPF0176 family
NG665_07660	COG0791	NLP P60 protein
NG665_07660	COG1388	LysM domain
NG665_07660	COG3103	Sh3 type 3 domain protein
NG665_07670	COG2252	PERMEase
NG665_07675	COG1482	cell wall glycoprotein biosynthetic process
NG665_07685	COG1278	Cold shock
NG665_07695	COG1842	Phage shock protein A
NG665_07705	COG0745	RESPONSE REGULATOR receiver
NG665_07710	COG2205	protein histidine kinase activity
NG665_07720	COG4221	oxidoreductase activity
NG665_07740	COG0459	protein refolding
NG665_07755	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
NG665_07765	COG0156	8-amino-7-oxononanoate synthase activity
NG665_07770	COG1063	alcohol dehydrogenase
NG665_07775	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
NG665_07785	COG1115	amino acid carrier protein
NG665_07805	COG0515	serine threonine protein kinase
NG665_07805	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
NG665_07810	COG3842	ATPase activity
NG665_07820	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
NG665_07860	COG2233	PERMEase
NG665_07880	COG0215	cysteine-tRNA ligase activity
NG665_07890	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
NG665_07895	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
NG665_07900	COG1329	Transcriptional regulator
NG665_07905	COG0588	phosphoglycerate mutase activity
NG665_07920	COG0446	pyridine nucleotide-disulphide oxidoreductase
NG665_08010	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NG665_08010	COG1754	DNA topoisomerase type I activity
NG665_08015	COG2890	protein-(glutamine-N5) methyltransferase activity
NG665_08030	COG1111	helicase
NG665_08030	COG1205	dead DEAH box helicase
NG665_08075	COG0596	Alpha beta hydrolase
NG665_08085	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NG665_08105	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
NG665_08120	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
NG665_08130	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NG665_08135	COG4868	Belongs to the UPF0371 family
NG665_08140	COG0242	peptide deformylase activity
NG665_08170	COG0326	Molecular chaperone. Has ATPase activity
NG665_08185	COG0590	tRNA wobble adenosine to inosine editing
NG665_08190	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
NG665_08220	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
NG665_08225	COG0561	phosphatase activity
NG665_08275	COG1940	carbohydrate kinase activity
NG665_08275	COG1846	Transcriptional regulator
NG665_08340	COG0189	ligase activity
NG665_08340	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
NG665_08450	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
NG665_08460	COG1643	Atp-dependent helicase
NG665_08475	COG0343	queuine tRNA-ribosyltransferase activity
NG665_08495	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
NG665_08495	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NG665_08515	COG0305	Participates in initiation and elongation during chromosome replication
NG665_08535	COG0359	binds to the 23S rRNA
NG665_08540	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
NG665_08550	COG0360	Binds together with S18 to 16S ribosomal RNA
NG665_08555	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NG665_08560	COG0628	permease
NG665_08570	COG0617	tRNA 3'-terminal CCA addition
NG665_08590	COG0492	ferredoxin-NADP+ reductase activity
NG665_08600	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NG665_08605	COG1475	DNA binding
NG665_08615	COG0357	Ribosomal RNA small subunit methyltransferase G
NG665_08620	COG1847	R3H domain protein
NG665_08625	COG0706	membrane insertase activity
NG665_08630	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
NG665_08635	COG0594	ribonuclease P activity
NG665_08640	COG0230	Belongs to the bacterial ribosomal protein bL34 family