locus-tag	class	description
AF_0004	ENOG4108IPW	abc transporter atp-binding protein
AF_0006	ENOG4108Q52	Methyltransferase cognate corrinoid protein
AF_0009	ENOG4108QZ0	Tetrahydromethanopterin S-methyltransferase (EC 2.1.1.86)
AF_0011	ENOG4108Q52	Methyltransferase cognate corrinoid protein
AF_0017	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AF_0018	ENOG4105CHU	acetyl-coa acetyltransferase
AF_0020	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AF_0021	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AF_0023	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
AF_0027	ENOG41067KJ	GYD family
AF_0033	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AF_0035	ENOG4105EIP	mannose-6-phosphate isomerase
AF_0036	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AF_0037	ENOG410813T	Joins Ado-cobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin) (By similarity)
AF_0038	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AF_0039	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
AF_0041	ENOG4105EY8	ABC transporter
AF_0043	ENOG4105CPK	Glycosyl transferase (Group 1
AF_0044	ENOG4105C0K	Gdp-mannose 4,6-dehydratase
AF_0050	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
AF_0051	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AF_0061	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AF_0062	ENOG41080XQ	Signal transduction protein with cbs domains
AF_0074	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AF_0076	ENOG4108RC0	Electron transport protein
AF_0080	ENOG4105C8Y	Acetylornithine aminotransferase
AF_0086	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AF_0089	ENOG4105CEY	Amp-dependent synthetase and ligase
AF_0092	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AF_0093	ENOG4105E0C	molybdate abc transporter
AF_0094	ENOG41066FR	extracellular solute-binding protein
AF_0106	ENOG4105CXT	aspartate transcarbamylase
AF_0107	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
AF_0108	ENOG41061GT	Aldolase
AF_0110	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AF_0112	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AF_0115	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
AF_0129	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
AF_0130	ENOG4105DGU	Histone deacetylase
AF_0140	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AF_0154	ENOG4107SJW	iron permease, FTR1
AF_0156	ENOG4108R3D	Electron transport complex
AF_0157	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AF_0159	ENOG4105DB1	molybdopterin oxidoreductase
AF_0161	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AF_0164	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AF_0166	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
AF_0167	ENOG4105CNW	domain protein
AF_0175	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AF_0176	ENOG4108JIG	Anaerobic dehydrogenase
AF_0185	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
AF_0186	ENOG4107QI6	Cysteine desulfurase
AF_0188	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
AF_0191	ENOG4105C59	p-type ATPase
AF_0192	ENOG4105C59	p-type ATPase
AF_0196	ENOG4105CEY	Amp-dependent synthetase and ligase
AF_0197	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AF_0198	ENOG4105DXM	phenylacetic acid degradation protein
AF_0200	ENOG4108IQE	Amp-dependent synthetase and ligase
AF_0205	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AF_0208	ENOG4105GR3	Histidine kinase
AF_0209	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
AF_0211	ENOG4105CJW	magnesium transporter
AF_0212	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AF_0216	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AF_0219	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AF_0220	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AF_0221	ENOG4108IV0	ABC, transporter
AF_0222	ENOG4105C0Z	ABC transporter
AF_0224	ENOG4105C32	Amino acid ABC transporter (Permease)
AF_0227	ENOG4105CQC	Prephenate dehydratase
AF_0228	ENOG4105FF2	Type I DHQase
AF_0229	ENOG4106M32	3-dehydroquinate synthase
AF_0230	ENOG41061GT	Aldolase
AF_0232	ENOG4105E5Q	amino acid AbC transporter
AF_0234	ENOG4105D4M	Lactamase_B
AF_0235	ENOG4105D0M	Protease HtpX homolog
AF_0238	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AF_0239	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
AF_0240	ENOG4105CPN	adenine deaminase
AF_0241	ENOG4108R96	Methyltransferase, YaeB family
AF_0242	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AF_0246	ENOG4105CE1	Ferrous iron transport protein b
AF_0252	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AF_0253	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AF_0254	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AF_0262	ENOG4105CEY	Amp-dependent synthetase and ligase
AF_0263	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AF_0270	ENOG4105D3R	alkyl hydroperoxide reductase
AF_0274	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AF_0276	ENOG4108K7V	UPF0284 protein
AF_0280	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AF_0283	ENOG4105CHU	acetyl-coa acetyltransferase
AF_0285	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AF_0287	ENOG4105C10	Electron transfer flavoprotein
AF_0290	ENOG4105EY8	ABC transporter
AF_0302	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AF_0324	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AF_0327	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AF_0328	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
AF_0339	ENOG4105C0A	alcohol dehydrogenase
AF_0344	ENOG4108YZ8	Superoxide reductase
AF_0356	ENOG4108RVA	ribokinase
AF_0358	ENOG4105CB5	ATP-dependent DNA helicase recG
AF_0364	ENOG4108IUQ	atp-dependent protease
AF_0366	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AF_0370	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AF_0371	ENOG4105GRF	N-glycosylase DNA lyase
AF_0372	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AF_0376	ENOG4105EYX	Acetyl-CoA decarbonylase synthase complex subunit gamma
AF_0377	ENOG4106HYN	CO dehydrogenase acetyl-CoA synthase delta subunit
AF_0378	ENOG41080XS	Cobyrinic acid ac-diamide synthase
AF_0379	ENOG4105E8X	CO dehydrogenase acetyl-CoA synthase complex beta subunit
AF_0386	ENOG4107QV3	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AF_0388	ENOG4105DVY	radical SAM domain protein
AF_0390	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
AF_0394	ENOG4105CQB	FAD linked oxidase domain protein
AF_0395	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AF_0400	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AF_0409	ENOG4105CHM	Aminotransferase
AF_0410	ENOG4105BZU	Histidine kinase
AF_0411	ENOG4105C8N	cysteinyl-tRNA synthetase
AF_0422	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AF_0423	ENOG4105CY1	sulfite reductase, dissimilatory-type alpha subunit
AF_0424	ENOG4105PJW	Sulfite reductase dissimilatory-type beta subunit
AF_0428	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AF_0431	ENOG4105EHG	Permease protein
AF_0434	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AF_0435	ENOG4105E39	Enoyl-CoA hydratase
AF_0436	ENOG4105C1G	acyl-Coa dehydrogenase
AF_0438	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AF_0440	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
AF_0441	ENOG4107WPW	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AF_0442	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AF_0448	ENOG4105BZU	Histidine kinase
AF_0449	ENOG4107YTP	response regulator receiver protein
AF_0450	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AF_0452	ENOG4105DNJ	May play a role in the repair of endogenous alkylation damage (By similarity)
AF_0455	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AF_0458	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AF_0459	ENOG4105EYF	MMPL domain protein
AF_0465	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AF_0468	ENOG4105DQU	oxidoreductase, subunit beta
AF_0469	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
AF_0473	ENOG4105C59	p-type ATPase
AF_0475	ENOG4105D6J	arsenicaL-resistance protein
AF_0477	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AF_0478	ENOG4105E8R	UPF0173 metal-dependent hydrolase
AF_0482	ENOG4105CY0	Metallo-Beta-Lactamase
AF_0484	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AF_0487	ENOG4105CUJ	penicillin amidase
AF_0492	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AF_0493	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AF_0494	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AF_0497	ENOG4105CQ2	DNA polymerase
AF_0499	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AF_0506	ENOG4105DF6	Fe-S oxidoreductase
AF_0508	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
AF_0509	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
AF_0512	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AF_0520	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AF_0522	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
AF_0527	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AF_0528	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
AF_0530	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AF_0531	ENOG4105D06	uba thif-type nad fad binding protein
AF_0535	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AF_0538	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AF_0544	ENOG4107QQM	Cysteine-rich domain
AF_0547	ENOG4107QQM	Cysteine-rich domain
AF_0550	ENOG41080U2	Amidohydrolase family
AF_0551	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
AF_0553	ENOG4105D06	uba thif-type nad fad binding protein
AF_0556	ENOG4107XUC	SirA family
AF_0557	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
AF_0559	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AF_0564	ENOG4107QI6	Cysteine desulfurase
AF_0565	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
AF_0568	ENOG4105CEY	Amp-dependent synthetase and ligase
AF_0570	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AF_0575	ENOG4105C5X	domain protein
AF_0580	ENOG4105CGK	Exodeoxyribonuclease III
AF_0581	ENOG4105CKK	Glycosyl transferase, family 2
AF_0584	ENOG4105EW9	transcriptional regulator AsnC family
AF_0588	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AF_0589	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AF_0590	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AF_0592	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AF_0596	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AF_0607	ENOG4107T8Q	Glycosyl transferase (Group 1
AF_0617	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AF_0621	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AF_0622	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AF_0623	ENOG4107QIM	DNA ligase
AF_0628	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AF_0629	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AF_0632	ENOG41083MR	nifu domain-containing protein
AF_0633	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AF_0639	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AF_0640	ENOG4105D7T	ABC transporter
AF_0647	ENOG4108HMX	isocitrate dehydrogenase (NADP)
AF_0654	ENOG4107S7U	Sulfide dehydrogenase
AF_0660	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
AF_0662	ENOG4107EFR	Flavocytochrome c
AF_0663	ENOG4105EWK	phytoene
AF_0665	ENOG4105D9P	serine threonine protein kinase
AF_0670	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AF_0671	ENOG4105C1G	acyl-Coa dehydrogenase
AF_0672	ENOG4105CEY	Amp-dependent synthetase and ligase
AF_0676	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AF_0677	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AF_0685	ENOG4105E39	Enoyl-CoA hydratase
AF_0687	ENOG4105CEY	Amp-dependent synthetase and ligase
AF_0691	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
AF_0696	ENOG4107QMS	site-determining protein
AF_0702	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
AF_0707	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AF_0710	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AF_0713	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AF_0723	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
AF_0724	ENOG4105E4R	Precorrin-3B C17-methyltransferase
AF_0726	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
AF_0728	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
AF_0731	ENOG4108JJB	ABC transporter
AF_0733	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AF_0737	ENOG4106C07	ThiamineS Protein
AF_0741	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
AF_0743	ENOG4105MRR	Transcriptional regulator (By similarity)
AF_0745	ENOG4105CS7	Catalyzes the conversion of dihydroorotate to orotate
AF_0747	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AF_0750	ENOG4105DQU	oxidoreductase, subunit beta
AF_0755	ENOG4105DF6	Fe-S oxidoreductase
AF_0756	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AF_0767	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AF_0768	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AF_0770	ENOG4105BZU	Histidine kinase
AF_0776	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AF_0781	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AF_0784	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AF_0786	ENOG4105D7N	magnesium and cobalt transport protein CorA
AF_0788	ENOG4108PCN	EamA-like transporter family
AF_0797	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
AF_0798	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
AF_0800	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AF_0806	ENOG4105DAA	L-lactate
AF_0808	ENOG4105CQB	FAD linked oxidase domain protein
AF_0811	ENOG4107QR9	Iron-sulfur cluster binding protein
AF_0815	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
AF_0818	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
AF_0819	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AF_0822	ENOG4108IV0	ABC, transporter
AF_0823	ENOG4105C0Z	ABC transporter
AF_0825	ENOG4105C32	Amino acid ABC transporter (Permease)
AF_0827	ENOG4105CP9	extracellular ligand-binding receptor
AF_0830	ENOG4105VCQ	rubredoxin
AF_0831	ENOG4108RAC	Rubrerythrin
AF_0833	ENOG4105MAX	Superoxide reductase
AF_0838	ENOG4105C1A	potassium transporter peripheral membrane
AF_0839	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AF_0840	ENOG4105CEY	Amp-dependent synthetase and ligase
AF_0841	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AF_0845	ENOG4105C1G	acyl-Coa dehydrogenase
AF_0847	ENOG4108IJ8	ABC transporter
AF_0848	ENOG41080XP	Cbs domain
AF_0851	ENOG4108DFU	YjeF-related protein N-terminus
AF_0852	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AF_0853	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AF_0855	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AF_0865	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AF_0866	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AF_0868	ENOG4105CQB	FAD linked oxidase domain protein
AF_0869	ENOG4105K8R	UPF0145 protein
AF_0871	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AF_0880	ENOG4105VCQ	rubredoxin
AF_0882	ENOG4105HDK	L-asparaginase
AF_0883	ENOG4105CH7	arginosuccinase
AF_0886	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AF_0887	ENOG4108JQ9	ABC transporter
AF_0888	ENOG4105UIB	(ABC) transporter
AF_0893	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AF_0904	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AF_0907	ENOG4105DJB	Major Facilitator Superfamily
AF_0909	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AF_0910	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AF_0914	ENOG4108ZJT	translation initiation factor, Sui1
AF_0916	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
AF_0917	ENOG4105EIH	LPPG Fo 2-phospho-L-lactate transferase
AF_0920	ENOG4105C5S	asparaginyl-tRNA synthetase
AF_0928	ENOG4107XGZ	Hydrolase
AF_0929	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AF_0930	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AF_0931	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AF_0932	ENOG4105CD5	CoA-binding domain protein
AF_0933	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AF_0935	ENOG4105D6E	homoserine dehydrogenase
AF_0937	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AF_0938	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AF_0939	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AF_0942	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AF_0943	ENOG4105E66	phosphoriboisomerase A
AF_0949	ENOG4105C5F	glutamine synthetase
AF_0950	ENOG4105QAX	Iron-sulfur
AF_0951	ENOG4108IFG	nitrite reductase, (NAD(P)H)
AF_0952	ENOG4105EYU	Glutamine amido-transferase
AF_0953	ENOG4105CBC	glutamate synthase
AF_0957	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AF_0958	ENOG4105DIK	(ABC) transporter
AF_0959	ENOG4108IUZ	ABC transporter
AF_0960	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
AF_0963	ENOG4105E39	Enoyl-CoA hydratase
AF_0969	ENOG4107QN1	sodium solute
AF_0972	ENOG41083X2	DNA polymerase III, epsilon subunit
AF_0973	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AF_0974	ENOG410846T	CoA-transferase family III
AF_0975	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AF_0977	ENOG4105BZU	Histidine kinase
AF_0980	ENOG4105E90	ABC transporter
AF_0981	ENOG4108IJ8	ABC transporter
AF_0982	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
AF_0984	ENOG4108IUW	ABC transporter
AF_0985	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AF_0986	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AF_0997	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AF_1005	ENOG4107QWP	ABC-2 type transporter
AF_1006	ENOG4105CJ1	ABC, transporter
AF_1009	ENOG4108NGU	Transcriptional regulator
AF_1014	ENOG4105C01	Dihydroxy-acid dehydratase
AF_1017	ENOG4107RBB	ABC transporter, permease
AF_1018	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AF_1021	ENOG4105CJ1	ABC, transporter
AF_1022	ENOG4105F4R	Transcriptional regulator mode
AF_1023	ENOG4107QZT	geranylgeranyl reductase
AF_1024	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
AF_1025	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AF_1026	ENOG4105C1G	acyl-Coa dehydrogenase
AF_1028	ENOG4105CHU	acetyl-coa acetyltransferase
AF_1029	ENOG4105CEY	Amp-dependent synthetase and ligase
AF_1032	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AF_1034	ENOG4105C8Q	Methyl-accepting chemotaxis
AF_1037	ENOG4105BZU	Histidine kinase
AF_1038	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
AF_1039	ENOG4107PHP	CheC --inhibitor of MCP methylation
AF_1040	ENOG4105CBS	Chea signal transduction histidine kinase
AF_1041	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AF_1042	ENOG4107YTP	response regulator receiver protein
AF_1044	ENOG4108V3W	Chemotaxis protein, CheW
AF_1045	ENOG4105C8Q	Methyl-accepting chemotaxis
AF_1063	ENOG4107YTP	response regulator receiver protein
AF_1064	ENOG4105FDK	ABC transporter
AF_1069	ENOG4108IA2	Sodium pantothenate symporter
AF_1070	ENOG4105DZS	Phenylacetate-CoA ligase
AF_1112	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AF_1117	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AF_1122	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AF_1125	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
AF_1128	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AF_1129	ENOG4108UJD	30S ribosomal protein S9
AF_1132	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AF_1133	ENOG4105CE9	30S ribosomal protein S2
AF_1142	ENOG4107Z36	nucleotidyl transferase
AF_1145	ENOG4105CYC	Transferase
AF_1146	ENOG4105BZA	Phosphoglycerate kinase
AF_1147	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AF_1148	ENOG4105FKN	transcriptional regulator, AsnC family
AF_1149	ENOG4107QRT	dEAD DEAH box helicase
AF_1157	ENOG4107QNG	Phosphoribosylglycinamide synthetase
AF_1164	ENOG41089ID	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AF_1166	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
AF_1167	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
AF_1169	ENOG4105VKD	bioY protein
AF_1170	ENOG4108JJB	ABC transporter
AF_1175	ENOG4105C1G	acyl-Coa dehydrogenase
AF_1177	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AF_1181	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AF_1184	ENOG4105BZU	Histidine kinase
AF_1186	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AF_1190	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AF_1191	ENOG4108IPT	Naphthoate synthase
AF_1192	ENOG4105CD5	CoA-binding domain protein
AF_1195	ENOG4105D1H	recombination factor protein RarA
AF_1197	ENOG4105CHU	acetyl-coa acetyltransferase
AF_1202	ENOG4105QAX	Iron-sulfur
AF_1206	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
AF_1207	ENOG4105CHR	reductase
AF_1210	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
AF_1211	ENOG4105CD5	CoA-binding domain protein
AF_1215	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AF_1216	ENOG4105DK7	lysyl-tRNA synthetase
AF_1219	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AF_1222	ENOG4107QN1	sodium solute
AF_1224	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
AF_1229	ENOG4105EYF	MMPL domain protein
AF_1232	ENOG4108NGU	Transcriptional regulator
AF_1240	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AF_1241	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AF_1242	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AF_1243	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AF_1245	ENOG4107S91	Sodium hydrogen exchanger
AF_1247	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AF_1248	ENOG4108UQV	Membrane
AF_1252	ENOG4107QSA	Oxaloacetate decarboxylase
AF_1255	ENOG4105DBV	ornithine carbamoyltransferase
AF_1256	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AF_1259	ENOG4108IJ8	ABC transporter
AF_1260	ENOG4108DGI	Phosphoribosylformylglycinamidine synthase I
AF_1261	ENOG4105CEY	Amp-dependent synthetase and ligase
AF_1262	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AF_1265	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
AF_1271	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AF_1272	ENOG4105C8V	SAICAR synthetase
AF_1273	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AF_1274	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AF_1275	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
AF_1277	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AF_1280	ENOG4105CAS	nag kinase
AF_1281	ENOG4108Z0Z	intracellular protease Pfpi family
AF_1285	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AF_1286	ENOG4105DGU	Histone deacetylase
AF_1287	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AF_1293	ENOG4105C1G	acyl-Coa dehydrogenase
AF_1296	ENOG4105MYT	Heat shock protein
AF_1297	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AF_1300	ENOG4105DA5	(ABC) transporter
AF_1304	ENOG4105CP7	Triose-phosphate isomerase
AF_1305	ENOG4108P4C	Formaldehyde-activating enzyme
AF_1308	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AF_1311	ENOG4105CSA	Coproporphyrinogen iii oxidase
AF_1315	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AF_1320	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AF_1321	ENOG4107R56	PP-loop domain protein
AF_1326	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AF_1328	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AF_1336	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AF_1338	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AF_1339	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AF_1340	ENOG4105BZN	citrate synthase
AF_1343	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AF_1344	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AF_1349	ENOG4105VCQ	rubredoxin
AF_1350	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AF_1354	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AF_1357	ENOG4105C8U	phosphate abc transporter
AF_1358	ENOG4105E2Z	phosphate ABC transporter (Permease
AF_1359	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AF_1360	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AF_1364	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AF_1367	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
AF_1368	ENOG4107RSS	Hydrogenase accessory protein HypB
AF_1370	ENOG4105CQS	hydrogenase expression formation protein HypD
AF_1378	ENOG4108USZ	hydrogenase
AF_1380	ENOG4105DPX	Hydrogenase, large subunit
AF_1381	ENOG4105E3S	small subunit
AF_1389	ENOG4108IV0	ABC, transporter
AF_1390	ENOG4105C0Z	ABC transporter
AF_1398	ENOG4105EWU	Squalene--hopene cyclase
AF_1399	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AF_1401	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
AF_1402	ENOG4105EHG	Permease protein
AF_1409	ENOG4107QMH	DNA methylase
AF_1414	ENOG4105FIK	Inherit from COG: dihydropteroate synthase
AF_1417	ENOG4105C5R	Aminotransferase
AF_1418	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AF_1420	ENOG4107QX8	SPFH domain, Band 7 family protein
AF_1421	ENOG4105DJZ	UPF0182 protein
AF_1423	ENOG4105DCI	Phosphohydrolase
AF_1425	ENOG4105E3H	phosphoglycerate mutase
AF_1426	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AF_1433	ENOG4108UUC	Protein of unknown function DUF99
AF_1435	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
AF_1440	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AF_1442	ENOG4107NFR	Fructose-1,6-bisphosphatase
AF_1443	ENOG4105EHU	Circadian clock protein KaiC
AF_1448	ENOG4105F7P	transcriptional regulator AsnC family
AF_1449	ENOG4105C6N	Formate acetyltransferase
AF_1450	ENOG4105F1A	Pyruvate formate-lyase
AF_1451	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AF_1452	ENOG4105BZU	Histidine kinase
AF_1453	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AF_1458	ENOG4108JA2	transcriptioN-repair coupling factor
AF_1463	ENOG4108IYU	L-aspartate oxidase
AF_1469	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AF_1470	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AF_1472	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AF_1475	ENOG4105KAV	tspo and mbr like protein
AF_1476	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
AF_1483	ENOG4105BZU	Histidine kinase
AF_1485	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AF_1486	ENOG4108MYP	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AF_1490	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AF_1491	ENOG4108VZM	50s ribosomal protein L10
AF_1506	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
AF_1510	ENOG4105CEY	Amp-dependent synthetase and ligase
AF_1511	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AF_1512	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AF_1516	ENOG4105PW4	Sugar fermentation stimulation protein homolog
AF_1520	ENOG4105CNW	domain protein
AF_1522	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
AF_1537	ENOG41081E8	Alpha beta hydrolase
AF_1538	ENOG4105CRW	Short chain fatty acid transporter
AF_1539	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AF_1540	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AF_1542	ENOG4105VUN	Transcriptional regulator
AF_1553	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
AF_1554	ENOG4105C3M	thioredoxin reductase
AF_1556	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AF_1580	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AF_1587	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
AF_1595	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AF_1599	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AF_1600	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AF_1601	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AF_1602	ENOG4105DDQ	anthranilate synthase
AF_1603	ENOG4105CRQ	synthase (Component I)
AF_1606	ENOG4105D38	putrescine abc transporter
AF_1607	ENOG4105F38	ABC transporter, permease
AF_1608	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AF_1609	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AF_1610	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
AF_1611	ENOG4108JVH	Protein of unknown function DUF43
AF_1612	ENOG4105C85	amino acid
AF_1618	ENOG4105D63	family UPF0324
AF_1619	ENOG4105D63	family UPF0324
AF_1621	ENOG4105HMI	Membrane
AF_1623	ENOG4105CHM	Aminotransferase
AF_1624	ENOG4105M00	molybdopterin converting factor, subunit 1
AF_1630	ENOG4108JEJ	Pyruvoyl-dependent arginine decarboxylase
AF_1638	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
AF_1639	ENOG4105BZU	Histidine kinase
AF_1640	ENOG4108RAC	Rubrerythrin
AF_1641	ENOG4105E39	Enoyl-CoA hydratase
AF_1642	ENOG4105CUT	histidyl-tRNA synthetase
AF_1643	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
AF_1645	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AF_1652	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AF_1653	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AF_1671	ENOG4105DZS	Phenylacetate-CoA ligase
AF_1674	ENOG4108MDK	Dehydrogenase
AF_1676	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AF_1677	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AF_1685	ENOG41080XS	Cobyrinic acid ac-diamide synthase
AF_1692	ENOG4105CSM	endonuclease III
AF_1693	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AF_1695	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AF_1698	ENOG4108V1U	phospholipid-binding protein
AF_1701	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
AF_1702	ENOG4105DDK	oxidoreductase, beta subunit
AF_1704	ENOG4105E63	Pfam:DUF178
AF_1706	ENOG4108MXF	Alpha Beta Hydrolase
AF_1708	ENOG4105DZR	Type I site-specific deoxyribonuclease
AF_1710	ENOG4105EKX	Restriction modification system DNA (Specificity
AF_1720	ENOG4105C7K	acetolactate synthase
AF_1721	ENOG41062D9	Histidine kinase
AF_1726	ENOG4105FDF	Could be involved in DNA repair (By similarity)
AF_1727	ENOG4105C6K	Malic enzyme
AF_1728	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AF_1730	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AF_1737	ENOG4105C7Z	Conserved Protein
AF_1741	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AF_1744	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
AF_1747	ENOG4108YZA	Nitrogen regulatory protein pii
AF_1748	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AF_1749	ENOG4105BZU	Histidine kinase
AF_1751	ENOG4105E3H	phosphoglycerate mutase
AF_1752	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AF_1755	ENOG4108UMN	azlc family
AF_1761	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AF_1764	ENOG4108UK2	deaminase
AF_1765	ENOG4105EYA	deoxyribonuclease
AF_1767	ENOG4105DEF	Extracellular solute-binding protein, family 5
AF_1768	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AF_1769	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AF_1771	ENOG4108JQ7	(ABC) transporter
AF_1772	ENOG4105CEY	Amp-dependent synthetase and ligase
AF_1773	ENOG4105DF6	Fe-S oxidoreductase
AF_1774	ENOG4107RY6	amino acid
AF_1777	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
AF_1778	ENOG4105K4W	Could be involved in septation (By similarity)
AF_1779	ENOG4105C5I	Dehydrogenase
AF_1780	ENOG4105C7K	acetolactate synthase
AF_1783	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AF_1787	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
AF_1788	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
AF_1795	ENOG4105CN9	Peptidase m42 family protein
AF_1797	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AF_1798	ENOG4107QXV	Phosphate transporter
AF_1801	ENOG4106FVC	RNA methyltransferase
AF_1811	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AF_1817	ENOG41067SE	Tetr family transcriptional regulator
AF_1819	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AF_1825	ENOG4105D65	subunit l
AF_1826	ENOG4105D65	subunit l
AF_1827	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AF_1829	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AF_1839	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AF_1840	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AF_1841	ENOG4108JJB	ABC transporter
AF_1843	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
AF_1849	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
AF_1854	ENOG4105CYC	Transferase
AF_1855	ENOG4105CEY	Amp-dependent synthetase and ligase
AF_1858	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AF_1884	ENOG4105CJ1	ABC, transporter
AF_1886	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AF_1887	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AF_1889	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AF_1891	ENOG4105CHV	Transcription elongation factor NusA
AF_1894	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AF_1896	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AF_1898	ENOG4107YTP	response regulator receiver protein
AF_1899	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AF_1902	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AF_1903	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AF_1905	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AF_1906	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AF_1909	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AF_1910	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AF_1912	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AF_1914	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AF_1915	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AF_1916	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AF_1918	ENOG41082SA	50s ribosomal protein l29
AF_1919	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AF_1920	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AF_1921	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AF_1922	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AF_1923	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AF_1925	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AF_1930	ENOG4105DCC	Formylmethanofuran dehydrogenase subunit A
AF_1932	ENOG4105CEY	Amp-dependent synthetase and ligase
AF_1935	ENOG41068T5	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT (By similarity)
AF_1936	ENOG4108T9Q	UPF0278 protein
AF_1938	ENOG4105CD5	CoA-binding domain protein
AF_1940	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AF_1941	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
AF_1950	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AF_1951	ENOG4105CTP	PilT protein domain protein
AF_1954	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AF_1955	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AF_1957	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
AF_1958	ENOG4105CMH	dehydratase
AF_1959	ENOG4105CIZ	coA-substrate-specific enzyme activase
AF_1960	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AF_1963	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AF_1968	ENOG4105E2R	ROK family
AF_1969	ENOG4105NBF	ammecr1 domain protein
AF_1971	ENOG4105VN1	Heat shock protein
AF_1974	ENOG4105D52	delta-aminolevulinic acid dehydratase
AF_1975	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AF_1976	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AF_1980	ENOG41060IM	Heme exporter protein
AF_1981	ENOG4105FAV	ABC, transporter
AF_1982	ENOG4105DIK	(ABC) transporter
AF_1983	ENOG4107XSR	periplasmic solute binding protein
AF_1985	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AF_1989	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AF_1995	ENOG4105C8J	)-transporter
AF_1998	ENOG4105DF6	Fe-S oxidoreductase
AF_2000	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AF_2002	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AF_2004	ENOG4107SJ9	decarboxylase
AF_2005	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AF_2006	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AF_2007	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AF_2009	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
AF_2013	ENOG4105DZS	Phenylacetate-CoA ligase
AF_2015	ENOG4105C7K	acetolactate synthase
AF_2017	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AF_2019	ENOG4105C0A	alcohol dehydrogenase
AF_2024	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AF_2032	ENOG4105BZU	Histidine kinase
AF_2033	ENOG4105CEY	Amp-dependent synthetase and ligase
AF_2034	ENOG4105DC7	peptidase M24
AF_2035	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AF_2036	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AF_2037	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AF_2038	ENOG4105F23	Fibronectin-binding protein
AF_2039	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AF_2042	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AF_2044	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AF_2045	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
AF_2047	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AF_2050	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
AF_2051	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AF_2052	ENOG4105DDK	oxidoreductase, beta subunit
AF_2053	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
AF_2054	ENOG4105WGB	oxidoreductase, delta subunit
AF_2057	ENOG4105C1G	acyl-Coa dehydrogenase
AF_2062	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AF_2071	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
AF_2073	ENOG4105FIE	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) (By similarity)
AF_2074	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AF_2075	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
AF_2084	ENOG4105D9Q	decarboxylase (Beta subunit)
AF_2085	ENOG4107QSA	Oxaloacetate decarboxylase
AF_2089	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AF_2097	ENOG4105C8M	UPF0272 protein
AF_2098	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AF_2099	ENOG4105DIA	mandelate racemase muconate lactonizing
AF_2100	ENOG4105C7K	acetolactate synthase
AF_2101	ENOG4105CPQ	Dehydrogenase
AF_2109	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AF_2111	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
AF_2116	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AF_2127	ENOG410811B	TRANSCRIPTIONal
AF_2128	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AF_2129	ENOG4105CHM	Aminotransferase
AF_2136	ENOG41082BM	Transcriptional regulator, arsr family
AF_2138	ENOG4105EAC	phosphoserine phosphatase
AF_2146	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AF_2148	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AF_2150	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AF_2151	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
AF_2155	ENOG4105CY0	Metallo-Beta-Lactamase
AF_2157	ENOG4105M7V	2'-5' rna ligase
AF_2173	ENOG4105EA8	2-Nitropropane dioxygenase
AF_2178	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AF_2179	ENOG4108ZAF	Molybdopterin
AF_2184	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AF_2185	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AF_2186	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AF_2192	ENOG4108QKW	cytochrome c-type biogenesis protein
AF_2194	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AF_2195	ENOG4105E0R	Deoxyhypusine synthase
AF_2196	ENOG4105I9Z	UPF0264 protein
AF_2199	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AF_2200	ENOG4105PTV	Nudix Hydrolase
AF_2207	ENOG4105FIE	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) (By similarity)
AF_2208	ENOG4105DWF	phosphomethylpyrimidine kinase
AF_2216	ENOG4107QSA	Oxaloacetate decarboxylase
AF_2217	ENOG4107QX3	carboxylase
AF_2218	ENOG4108ZVT	methylmalonyl-coA epimerase
AF_2224	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AF_2226	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
AF_2229	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AF_2232	ENOG4105N80	Ferric uptake regulator, Fur family
AF_2233	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AF_2237	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AF_2238	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AF_2242	ENOG4105C83	adenylosuccinate lyase
AF_2243	ENOG4105CHU	acetyl-coa acetyltransferase
AF_2244	ENOG4105C1G	acyl-Coa dehydrogenase
AF_2249	ENOG4107YTP	response regulator receiver protein
AF_2250	ENOG4105CD3	dihydroorotase
AF_2251	ENOG4105CEV	competence damage-inducible protein
AF_2252	ENOG4105CDH	Citrulline--aspartate ligase
AF_2253	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
AF_2254	ENOG4105C1J	atp-dependent rna helicase
AF_2255	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AF_2257	ENOG4105CPF	Cell wall formation (By similarity)
AF_2258	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AF_2264	ENOG4107YAU	phenylacetic acid degradation protein
AF_2265	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AF_2266	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AF_2267	ENOG4108RCM	Nitroreductase
AF_2269	ENOG4105D1F	ATP-binding protein
AF_2273	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AF_2277	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
AF_2281	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
AF_2283	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AF_2284	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AF_2285	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AF_2286	ENOG4105EAH	synthase
AF_2287	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
AF_2288	ENOG4105CAS	nag kinase
AF_2289	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AF_2290	ENOG4105DGU	Histone deacetylase
AF_2299	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AF_2301	ENOG4108JEJ	Pyruvoyl-dependent arginine decarboxylase
AF_2310	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
AF_2313	ENOG4105DXM	phenylacetic acid degradation protein
AF_2314	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AF_2322	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AF_2327	ENOG4105E2X	shikimate dehydrogenase
AF_2328	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AF_2329	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AF_2334	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AF_2336	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
AF_2350	ENOG4105C0D	helicase
AF_2363	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
AF_2365	ENOG4105DIW	FeS assembly protein SUFB
AF_2366	ENOG4105CHM	Aminotransferase
AF_2367	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
AF_2368	ENOG4105CEY	Amp-dependent synthetase and ligase
AF_2372	ENOG4107TK4	histidinol-phosphate phosphatase
AF_2373	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AF_2380	ENOG4105D1F	ATP-binding protein
AF_2382	ENOG4105D1F	ATP-binding protein
AF_2384	ENOG4108J2R	molybdopterin oxidoreductase
AF_2385	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AF_2389-C	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AF_2395	ENOG4105KST	dependent repressor
AF_2399	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AF_2406	ENOG4108I5C	dEAD DEAH box helicase
AF_2407	ENOG4105C5X	domain protein
AF_2409	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AF_2412	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AF_2413	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
AF_2419	ENOG4108UXN	response regulator
AF_2420	ENOG4105BZU	Histidine kinase
AF_2421	ENOG4105C8T	Leucyl-tRNA synthetase
AF_2425	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AF_2429	ENOG4105E39	Enoyl-CoA hydratase
AF_2431	ENOG4108JEJ	Pyruvoyl-dependent arginine decarboxylase
AF_2434	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
AF_2435	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)