AF_2430 cd63e5635c26d57c25b50897f14d719e 372 SMART SM00226 255 369 1.8E-40 T 31-10-2018 IPR023485 Phosphotyrosine protein phosphatase I AF_2430 cd63e5635c26d57c25b50897f14d719e 372 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 257 334 1.5E-11 T 31-10-2018 IPR023485 Phosphotyrosine protein phosphatase I AF_2430 cd63e5635c26d57c25b50897f14d719e 372 Pfam PF00149 Calcineurin-like phosphoesterase 1 179 1.8E-16 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AF_2430 cd63e5635c26d57c25b50897f14d719e 372 SUPERFAMILY SSF52788 253 370 1.7E-21 T 31-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily AF_2430 cd63e5635c26d57c25b50897f14d719e 372 Gene3D G3DSA:3.40.50.2300 252 371 1.7E-21 T 31-10-2018 AF_2430 cd63e5635c26d57c25b50897f14d719e 372 SUPERFAMILY SSF56300 1 228 1.7E-46 T 31-10-2018 AF_2430 cd63e5635c26d57c25b50897f14d719e 372 Gene3D G3DSA:3.60.21.10 1 246 5.6E-34 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like AF_1334 80b905da4d39a38cea99b51b0f9e88e0 58 SUPERFAMILY SSF57829 2 55 1.81E-19 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AF_1334 80b905da4d39a38cea99b51b0f9e88e0 58 ProSitePatterns PS01168 Ribosomal protein S27e signature. 9 41 - T 31-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1334 80b905da4d39a38cea99b51b0f9e88e0 58 Pfam PF01667 Ribosomal protein S27 2 55 7.3E-30 T 31-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1334 80b905da4d39a38cea99b51b0f9e88e0 58 Gene3D G3DSA:2.20.25.100 1 58 7.2E-32 T 31-10-2018 IPR023407 Ribosomal protein S27e, zinc-binding domain superfamily AF_1334 80b905da4d39a38cea99b51b0f9e88e0 58 Hamap MF_00371 30S ribosomal protein S27e [rps27e]. 1 54 18.784 T 31-10-2018 IPR000592 Ribosomal protein S27e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0957 14efce871196650443fa68c57e3a6109 489 TIGRFAM TIGR02090 LEU1_arch: isopropylmalate/citramalate/homocitrate synthases 3 366 3.4E-188 T 31-10-2018 IPR011830 Isopropylmalate/citramalate/homocitrate synthase GO:0019752|GO:0046912 AF_0957 14efce871196650443fa68c57e3a6109 489 SUPERFAMILY SSF110921 378 488 5.23E-23 T 31-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AF_0957 14efce871196650443fa68c57e3a6109 489 Gene3D G3DSA:1.10.238.260 268 382 6.6E-35 T 31-10-2018 AF_0957 14efce871196650443fa68c57e3a6109 489 Gene3D G3DSA:3.30.160.270 383 488 1.1E-7 T 31-10-2018 AF_0957 14efce871196650443fa68c57e3a6109 489 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 10 26 - T 31-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AF_0957 14efce871196650443fa68c57e3a6109 489 SMART SM00917 356 489 1.2E-34 T 31-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AF_0957 14efce871196650443fa68c57e3a6109 489 Gene3D G3DSA:3.20.20.70 1 264 7.0E-93 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0957 14efce871196650443fa68c57e3a6109 489 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 190 203 - T 31-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AF_0957 14efce871196650443fa68c57e3a6109 489 Pfam PF08502 LeuA allosteric (dimerisation) domain 357 488 8.8E-38 T 31-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AF_0957 14efce871196650443fa68c57e3a6109 489 SUPERFAMILY SSF51569 3 279 6.41E-87 T 31-10-2018 AF_0957 14efce871196650443fa68c57e3a6109 489 Pfam PF00682 HMGL-like 2 261 1.3E-83 T 31-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AF_0957 14efce871196650443fa68c57e3a6109 489 Hamap MF_01028 Putative (R)-citramalate synthase CimA [cimA]. 10 489 80.173 T 31-10-2018 IPR024890 (R)-citramalate synthase CimA GO:0043714 KEGG: 00290+2.3.1.182|KEGG: 00660+2.3.1.182|MetaCyc: PWY-5101 AF_0076 8c8f6777b48b71d468ff6401e35357e5 136 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 114 125 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0076 8c8f6777b48b71d468ff6401e35357e5 136 Gene3D G3DSA:3.30.70.20 6 117 1.5E-20 T 31-10-2018 AF_0076 8c8f6777b48b71d468ff6401e35357e5 136 Pfam PF13187 4Fe-4S dicluster domain 56 103 7.6E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0076 8c8f6777b48b71d468ff6401e35357e5 136 Gene3D G3DSA:3.30.70.20 62 113 1.5E-20 T 31-10-2018 AF_0076 8c8f6777b48b71d468ff6401e35357e5 136 Pfam PF12800 4Fe-4S binding domain 10 23 0.3 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0076 8c8f6777b48b71d468ff6401e35357e5 136 Pfam PF00037 4Fe-4S binding domain 114 129 1.4E-4 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0076 8c8f6777b48b71d468ff6401e35357e5 136 SUPERFAMILY SSF54862 3 132 5.13E-31 T 31-10-2018 AF_1959 4d2000d18370a1b8e1b7ebd1f7f6b406 251 TIGRFAM TIGR00241 CoA_E_activ: putative CoA-substrate-specific enzyme activase 2 250 1.2E-117 T 31-10-2018 IPR008275 CoA enzyme activase AF_1959 4d2000d18370a1b8e1b7ebd1f7f6b406 251 Gene3D G3DSA:3.30.420.40 5 251 1.5E-88 T 31-10-2018 AF_1959 4d2000d18370a1b8e1b7ebd1f7f6b406 251 Gene3D G3DSA:3.30.420.40 95 234 1.5E-88 T 31-10-2018 AF_1959 4d2000d18370a1b8e1b7ebd1f7f6b406 251 SUPERFAMILY SSF53067 1 251 5.37E-43 T 31-10-2018 AF_1959 4d2000d18370a1b8e1b7ebd1f7f6b406 251 Pfam PF01869 BadF/BadG/BcrA/BcrD ATPase family 5 251 2.6E-80 T 31-10-2018 IPR002731 ATPase, BadF/BadG/BcrA/BcrD type Reactome: R-HSA-446210 AF_1486 c3e9ab105f513d9c23d2a65929fa6729 471 Hamap MF_01904 Phosphoenolpyruvate carboxylase [ppcA]. 1 471 38.424 T 31-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AF_1486 c3e9ab105f513d9c23d2a65929fa6729 471 TIGRFAM TIGR02751 PEPCase_arch: phosphoenolpyruvate carboxylase 2 471 4.1E-193 T 31-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AF_1486 c3e9ab105f513d9c23d2a65929fa6729 471 SUPERFAMILY SSF51621 118 410 3.4E-32 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AF_1486 c3e9ab105f513d9c23d2a65929fa6729 471 PIRSF PIRSF006677 1 471 4.4E-191 T 31-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AF_1486 c3e9ab105f513d9c23d2a65929fa6729 471 Pfam PF14010 Phosphoenolpyruvate carboxylase 2 471 5.0E-184 T 31-10-2018 IPR007566 Phosphoenolpyruvate carboxylase, archaeal-type GO:0006099|GO:0008964|GO:0015977 KEGG: 00620+4.1.1.31|KEGG: 00680+4.1.1.31|KEGG: 00710+4.1.1.31|KEGG: 00720+4.1.1.31|MetaCyc: PWY-1622|MetaCyc: PWY-241|MetaCyc: PWY-5913|MetaCyc: PWY-6142|MetaCyc: PWY-6146|MetaCyc: PWY-6549|MetaCyc: PWY-7115|MetaCyc: PWY-7117|MetaCyc: PWY-7124 AF_2406 00697f9e2aa4e5ab677441668d38bc38 766 SMART SM00490 311 390 4.3E-22 T 31-10-2018 IPR001650 Helicase, C-terminal AF_2406 00697f9e2aa4e5ab677441668d38bc38 766 Gene3D G3DSA:3.40.50.300 63 262 2.6E-41 T 31-10-2018 AF_2406 00697f9e2aa4e5ab677441668d38bc38 766 Pfam PF00271 Helicase conserved C-terminal domain 290 390 4.4E-19 T 31-10-2018 IPR001650 Helicase, C-terminal AF_2406 00697f9e2aa4e5ab677441668d38bc38 766 Gene3D G3DSA:3.40.50.300 275 476 7.9E-30 T 31-10-2018 AF_2406 00697f9e2aa4e5ab677441668d38bc38 766 SMART SM00487 82 280 1.8E-37 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AF_2406 00697f9e2aa4e5ab677441668d38bc38 766 SUPERFAMILY SSF52540 97 399 5.6E-49 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2406 00697f9e2aa4e5ab677441668d38bc38 766 Pfam PF09369 Domain of unknown function (DUF1998) 645 718 2.3E-7 T 31-10-2018 IPR018973 DEAD/DEAH-box helicase, putative AF_2406 00697f9e2aa4e5ab677441668d38bc38 766 Pfam PF00270 DEAD/DEAH box helicase 88 249 1.3E-25 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AF_1020 657bda08dffb502c8cbc53224612f7f3 165 Pfam PF01842 ACT domain 94 157 2.1E-8 T 31-10-2018 IPR002912 ACT domain AF_1020 657bda08dffb502c8cbc53224612f7f3 165 PIRSF PIRSF004897 1 165 1.2E-69 T 31-10-2018 IPR014424 Uncharacterised conserved protein UCP004897, ACT- type AF_1020 657bda08dffb502c8cbc53224612f7f3 165 SUPERFAMILY SSF55021 103 163 3.72E-6 T 31-10-2018 AF_1157 378e8ccc831119921742f34146412bc8 470 SUPERFAMILY SSF51246 387 467 3.14E-18 T 31-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AF_1157 378e8ccc831119921742f34146412bc8 470 TIGRFAM TIGR00877 purD: phosphoribosylamine--glycine ligase 1 469 1.1E-183 T 31-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AF_1157 378e8ccc831119921742f34146412bc8 470 SUPERFAMILY SSF52440 1 108 1.35E-23 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AF_1157 378e8ccc831119921742f34146412bc8 470 SMART SM01209 109 334 8.9E-88 T 31-10-2018 AF_1157 378e8ccc831119921742f34146412bc8 470 SUPERFAMILY SSF56059 110 360 8.31E-42 T 31-10-2018 AF_1157 378e8ccc831119921742f34146412bc8 470 Pfam PF02844 Phosphoribosylglycinamide synthetase, N domain 1 108 8.3E-26 T 31-10-2018 IPR020562 Phosphoribosylglycinamide synthetase, N-terminal GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AF_1157 378e8ccc831119921742f34146412bc8 470 Pfam PF02843 Phosphoribosylglycinamide synthetase, C domain 387 466 1.6E-18 T 31-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AF_1157 378e8ccc831119921742f34146412bc8 470 Gene3D G3DSA:3.40.50.20 2 101 9.1E-27 T 31-10-2018 AF_1157 378e8ccc831119921742f34146412bc8 470 Gene3D G3DSA:3.30.1490.20 127 197 4.1E-29 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AF_1157 378e8ccc831119921742f34146412bc8 470 Hamap MF_00138 Phosphoribosylamine--glycine ligase [purD]. 1 469 37.889 T 31-10-2018 IPR000115 Phosphoribosylglycinamide synthetase GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AF_1157 378e8ccc831119921742f34146412bc8 470 SMART SM01210 368 469 2.0E-26 T 31-10-2018 IPR020560 Phosphoribosylglycinamide synthetase, C-domain GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AF_1157 378e8ccc831119921742f34146412bc8 470 Gene3D G3DSA:3.90.600.10 385 470 9.5E-23 T 31-10-2018 IPR037123 Phosphoribosylglycinamide synthetase, C-domain superfamily GO:0004637|GO:0009113 KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AF_1157 378e8ccc831119921742f34146412bc8 470 Pfam PF01071 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain 109 334 2.2E-84 T 31-10-2018 IPR020561 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain KEGG: 00230+6.3.4.13|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AF_1166 96363a85ddcb060301ebccdd6ff28b15 581 SUPERFAMILY SSF52540 180 440 4.38E-85 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1166 96363a85ddcb060301ebccdd6ff28b15 581 Hamap MF_00309 V-type ATP synthase alpha chain [atpA]. 7 581 52.933 T 31-10-2018 IPR022878 V-type ATP synthase catalytic alpha chain GO:0046034 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AF_1166 96363a85ddcb060301ebccdd6ff28b15 581 SUPERFAMILY SSF47917 447 535 1.28E-23 T 31-10-2018 AF_1166 96363a85ddcb060301ebccdd6ff28b15 581 Gene3D G3DSA:3.40.50.300 78 435 3.5E-180 T 31-10-2018 AF_1166 96363a85ddcb060301ebccdd6ff28b15 581 SUPERFAMILY SSF50615 8 75 7.06E-10 T 31-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AF_1166 96363a85ddcb060301ebccdd6ff28b15 581 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 214 435 6.8E-95 T 31-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AF_1166 96363a85ddcb060301ebccdd6ff28b15 581 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 426 435 - T 31-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AF_1166 96363a85ddcb060301ebccdd6ff28b15 581 TIGRFAM TIGR01043 ATP_syn_A_arch: ATP synthase archaeal, A subunit 9 578 0.0 T 31-10-2018 IPR005726 ATP synthase alpha chain, archaea GO:0015986|GO:0033178|GO:0046961 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AF_1166 96363a85ddcb060301ebccdd6ff28b15 581 Gene3D G3DSA:2.40.30.20 2 76 1.9E-25 T 31-10-2018 IPR023366 ATP synthase subunit alpha, N-terminal domain-like superfamily KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AF_1166 96363a85ddcb060301ebccdd6ff28b15 581 Pfam PF16886 ATPsynthase alpha/beta subunit N-term extension 89 205 8.4E-42 T 31-10-2018 IPR031686 ATPsynthase alpha/beta subunit, N-terminal extension KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980|Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AF_1166 96363a85ddcb060301ebccdd6ff28b15 581 Gene3D G3DSA:1.10.1140.10 436 580 2.6E-46 T 31-10-2018 IPR024034 ATPase, F1/V1 complex, beta/alpha subunit, C-terminal KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AF_1166 96363a85ddcb060301ebccdd6ff28b15 581 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 12 73 4.1E-14 T 31-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AF_1166 96363a85ddcb060301ebccdd6ff28b15 581 Gene3D G3DSA:2.40.50.100 120 187 3.5E-180 T 31-10-2018 AF_1458 d9e59c1dc132fc64c2cd50b45bec1b22 741 Pfam PF12826 Helix-hairpin-helix motif 679 729 5.3E-11 T 31-10-2018 AF_1458 d9e59c1dc132fc64c2cd50b45bec1b22 741 SMART SM00487 12 211 8.7E-33 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AF_1458 d9e59c1dc132fc64c2cd50b45bec1b22 741 Gene3D G3DSA:1.20.1320.20 216 342 3.4E-92 T 31-10-2018 AF_1458 d9e59c1dc132fc64c2cd50b45bec1b22 741 Pfam PF02732 ERCC4 domain 525 645 4.0E-27 T 31-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 AF_1458 d9e59c1dc132fc64c2cd50b45bec1b22 741 Gene3D G3DSA:1.10.150.20 662 733 1.3E-20 T 31-10-2018 AF_1458 d9e59c1dc132fc64c2cd50b45bec1b22 741 SUPERFAMILY SSF47781 660 729 1.11E-13 T 31-10-2018 IPR010994 RuvA domain 2-like AF_1458 d9e59c1dc132fc64c2cd50b45bec1b22 741 Pfam PF00270 DEAD/DEAH box helicase 22 175 2.6E-21 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AF_1458 d9e59c1dc132fc64c2cd50b45bec1b22 741 Gene3D G3DSA:3.40.50.300 8 203 2.2E-68 T 31-10-2018 AF_1458 d9e59c1dc132fc64c2cd50b45bec1b22 741 SMART SM00891 522 603 4.7E-27 T 31-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 AF_1458 d9e59c1dc132fc64c2cd50b45bec1b22 741 SUPERFAMILY SSF52980 520 649 7.78E-35 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AF_1458 d9e59c1dc132fc64c2cd50b45bec1b22 741 Pfam PF00271 Helicase conserved C-terminal domain 347 463 3.9E-22 T 31-10-2018 IPR001650 Helicase, C-terminal AF_1458 d9e59c1dc132fc64c2cd50b45bec1b22 741 SMART SM00490 376 464 7.3E-22 T 31-10-2018 IPR001650 Helicase, C-terminal AF_1458 d9e59c1dc132fc64c2cd50b45bec1b22 741 Gene3D G3DSA:3.40.50.10130 517 659 1.5E-48 T 31-10-2018 AF_1458 d9e59c1dc132fc64c2cd50b45bec1b22 741 Gene3D G3DSA:3.40.50.300 213 481 3.4E-92 T 31-10-2018 AF_1458 d9e59c1dc132fc64c2cd50b45bec1b22 741 SUPERFAMILY SSF52540 58 482 1.66E-54 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0770 af7bac5c42003c355bc7f728c181fa76 531 SUPERFAMILY SSF55785 73 196 8.66E-31 T 31-10-2018 IPR035965 PAS domain superfamily AF_0770 af7bac5c42003c355bc7f728c181fa76 531 SUPERFAMILY SSF55785 195 319 1.05E-28 T 31-10-2018 IPR035965 PAS domain superfamily AF_0770 af7bac5c42003c355bc7f728c181fa76 531 SMART SM00387 426 530 1.4E-24 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_0770 af7bac5c42003c355bc7f728c181fa76 531 SMART SM00091 88 153 5.9E-13 T 31-10-2018 IPR000014 PAS domain AF_0770 af7bac5c42003c355bc7f728c181fa76 531 SMART SM00091 210 275 2.1E-10 T 31-10-2018 IPR000014 PAS domain AF_0770 af7bac5c42003c355bc7f728c181fa76 531 Gene3D G3DSA:1.10.287.130 344 392 4.6E-29 T 31-10-2018 AF_0770 af7bac5c42003c355bc7f728c181fa76 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 516 529 3.3E-8 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_0770 af7bac5c42003c355bc7f728c181fa76 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 462 476 3.3E-8 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_0770 af7bac5c42003c355bc7f728c181fa76 531 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 510 3.3E-8 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_0770 af7bac5c42003c355bc7f728c181fa76 531 Gene3D G3DSA:3.30.450.20 197 319 4.1E-27 T 31-10-2018 AF_0770 af7bac5c42003c355bc7f728c181fa76 531 Gene3D G3DSA:3.30.450.20 72 196 6.2E-31 T 31-10-2018 AF_0770 af7bac5c42003c355bc7f728c181fa76 531 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 429 529 3.2E-19 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_0770 af7bac5c42003c355bc7f728c181fa76 531 Pfam PF08447 PAS fold 234 305 7.0E-15 T 31-10-2018 IPR013655 PAS fold-3 GO:0005515 AF_0770 af7bac5c42003c355bc7f728c181fa76 531 SUPERFAMILY SSF55874 397 529 1.83E-26 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_0770 af7bac5c42003c355bc7f728c181fa76 531 Gene3D G3DSA:3.30.565.10 394 528 4.6E-29 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_0770 af7bac5c42003c355bc7f728c181fa76 531 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 85 205 3.7E-36 T 31-10-2018 IPR000014 PAS domain AF_0770 af7bac5c42003c355bc7f728c181fa76 531 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 206 328 6.3E-33 T 31-10-2018 IPR000014 PAS domain AF_0770 af7bac5c42003c355bc7f728c181fa76 531 SMART SM00086 281 321 0.0045 T 31-10-2018 IPR001610 PAC motif AF_0770 af7bac5c42003c355bc7f728c181fa76 531 SMART SM00086 158 198 0.002 T 31-10-2018 IPR001610 PAC motif AF_0770 af7bac5c42003c355bc7f728c181fa76 531 Pfam PF13426 PAS domain 99 197 6.1E-17 T 31-10-2018 IPR000014 PAS domain AF_0770 af7bac5c42003c355bc7f728c181fa76 531 SMART SM00388 334 395 0.0087 T 31-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AF_0749 985e828d567d614fa43fce0c9ff22064 532 Gene3D G3DSA:3.40.920.10 1 164 5.1E-16 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AF_0749 985e828d567d614fa43fce0c9ff22064 532 SUPERFAMILY SSF53323 2 156 3.27E-18 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AF_0749 985e828d567d614fa43fce0c9ff22064 532 TIGRFAM TIGR03710 OAFO_sf: 2-oxoacid:acceptor oxidoreductase, alpha subunit 2 526 4.9E-152 T 31-10-2018 IPR022367 2-oxoacid:acceptor oxidoreductase, alpha subunit KEGG: 00020+1.2.7.3|KEGG: 00720+1.2.7.3|MetaCyc: PWY-5392|MetaCyc: PWY-6969 AF_0749 985e828d567d614fa43fce0c9ff22064 532 SUPERFAMILY SSF52518 178 422 5.4E-49 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold AF_0749 985e828d567d614fa43fce0c9ff22064 532 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 190 417 4.9E-58 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 AF_0749 985e828d567d614fa43fce0c9ff22064 532 Gene3D G3DSA:3.40.50.920 435 530 1.2E-11 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AF_0749 985e828d567d614fa43fce0c9ff22064 532 SUPERFAMILY SSF52922 435 529 5.38E-8 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AF_0749 985e828d567d614fa43fce0c9ff22064 532 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 9 160 4.5E-21 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AF_0749 985e828d567d614fa43fce0c9ff22064 532 Gene3D G3DSA:3.40.50.970 167 360 1.2E-57 T 31-10-2018 AF_0481 bd713e0884571f4d55d8ac27a7dc7eaf 213 TIGRFAM TIGR03634 arc_protsome_B: proteasome endopeptidase complex, archaeal, beta subunit 11 195 2.8E-83 T 31-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 AF_0481 bd713e0884571f4d55d8ac27a7dc7eaf 213 Gene3D G3DSA:3.60.20.10 1 213 1.7E-69 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AF_0481 bd713e0884571f4d55d8ac27a7dc7eaf 213 ProSitePatterns PS00854 Proteasome beta-type subunits signature. 15 62 - T 31-10-2018 IPR016050 Proteasome beta-type subunit, conserved site GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AF_0481 bd713e0884571f4d55d8ac27a7dc7eaf 213 Pfam PF00227 Proteasome subunit 9 191 9.5E-59 T 31-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AF_0481 bd713e0884571f4d55d8ac27a7dc7eaf 213 PRINTS PR00141 Proteasome component signature 177 188 3.2E-8 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AF_0481 bd713e0884571f4d55d8ac27a7dc7eaf 213 PRINTS PR00141 Proteasome component signature 141 152 3.2E-8 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AF_0481 bd713e0884571f4d55d8ac27a7dc7eaf 213 PRINTS PR00141 Proteasome component signature 19 34 3.2E-8 T 31-10-2018 IPR000243 Peptidase T1A, proteasome beta-subunit GO:0004175|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AF_0481 bd713e0884571f4d55d8ac27a7dc7eaf 213 SUPERFAMILY SSF56235 5 211 7.33E-67 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AF_0481 bd713e0884571f4d55d8ac27a7dc7eaf 213 Hamap MF_02113_A Proteasome subunit beta [prcB]. 7 204 38.671 T 31-10-2018 IPR019983 Peptidase T1A, proteasome beta-subunit, archaeal GO:0004175|GO:0005839|GO:0051603 AF_0346 e99301f67347ee0e8497b833d761bd7d 204 SUPERFAMILY SSF55008 139 201 7.46E-10 T 31-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 AF_0346 e99301f67347ee0e8497b833d761bd7d 204 Pfam PF00403 Heavy-metal-associated domain 142 197 3.2E-8 T 31-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AF_0346 e99301f67347ee0e8497b833d761bd7d 204 ProSitePatterns PS01047 Heavy-metal-associated domain. 144 172 - T 31-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 AF_0346 e99301f67347ee0e8497b833d761bd7d 204 Gene3D G3DSA:2.20.25.270 1 61 8.7E-33 T 31-10-2018 AF_0346 e99301f67347ee0e8497b833d761bd7d 204 Gene3D G3DSA:1.10.10.1100 62 130 9.8E-30 T 31-10-2018 AF_0346 e99301f67347ee0e8497b833d761bd7d 204 Gene3D G3DSA:3.30.70.100 139 202 1.7E-13 T 31-10-2018 AF_2043 b5a2ebdcd7cdae372afd4e9a4e78ee86 61 SUPERFAMILY SSF143560 1 60 1.7E-16 T 31-10-2018 IPR036839 7,8-dihydroneopterin aldolase (MptD) superfamily GO:0004150 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AF_2043 b5a2ebdcd7cdae372afd4e9a4e78ee86 61 Gene3D G3DSA:3.30.1300.20 1 61 1.1E-12 T 31-10-2018 IPR036839 7,8-dihydroneopterin aldolase (MptD) superfamily GO:0004150 KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AF_2043 b5a2ebdcd7cdae372afd4e9a4e78ee86 61 Pfam PF04038 Dihydroneopterin aldolase 2 60 2.0E-12 T 31-10-2018 IPR007181 Dihydroneopterin aldolase MtpD, C-terminal domain KEGG: 00790+4.1.2.25|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 TIGRFAM TIGR01054 rgy: reverse gyrase 217 1053 0.0 T 31-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 Gene3D G3DSA:1.10.460.10 680 1047 1.9E-165 T 31-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 SUPERFAMILY SSF56712 502 1052 3.66E-147 T 31-10-2018 IPR023405 DNA topoisomerase, type IA, core domain AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 Pfam PF00270 DEAD/DEAH box helicase 59 228 7.2E-12 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 SMART SM00487 53 252 3.0E-25 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 Pfam PF01131 DNA topoisomerase 735 1042 9.2E-59 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 Pfam PF01131 DNA topoisomerase 676 732 3.1E-13 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 Gene3D G3DSA:3.40.50.140 505 585 0.0 T 31-10-2018 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 SUPERFAMILY SSF52540 252 498 5.65E-48 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 Gene3D G3DSA:2.20.20.30 1 29 1.2E-7 T 31-10-2018 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 Gene3D G3DSA:2.60.510.20 733 953 1.9E-165 T 31-10-2018 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 Gene3D G3DSA:3.40.50.300 33 245 0.0 T 31-10-2018 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 Gene3D G3DSA:1.10.720.70 353 425 0.0 T 31-10-2018 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 SMART SM00493 506 652 2.4E-40 T 31-10-2018 IPR006171 TOPRIM domain AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 SUPERFAMILY SSF52540 3 241 3.85E-41 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 Gene3D G3DSA:2.20.20.30 32 582 0.0 T 31-10-2018 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 Gene3D G3DSA:3.40.50.300 246 504 0.0 T 31-10-2018 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 Hamap MF_01125 Reverse gyrase [rgy]. 1 1054 60.86 T 31-10-2018 IPR005736 Reverse gyrase GO:0003677|GO:0003916|GO:0006265 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 Pfam PF01751 Toprim domain 508 661 1.4E-23 T 31-10-2018 IPR006171 TOPRIM domain AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 Gene3D G3DSA:1.10.290.10 772 890 1.9E-165 T 31-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 969 983 7.5E-27 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 626 639 7.5E-27 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 879 895 7.5E-27 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 804 813 7.5E-27 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 711 729 7.5E-27 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 SMART SM00436 652 738 1.5E-36 T 31-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 AF_1024 18cff9ce1385adb964f228ed31ea7bb4 1054 SMART SM00437 762 1006 6.2E-103 T 31-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 AF_0646 2512c9397a35f3ce2623e776d2de6a81 275 ProSitePatterns PS01053 Arginase family signature. 199 220 - T 31-10-2018 IPR020855 Ureohydrolase, manganese-binding site GO:0016813|GO:0046872 AF_0646 2512c9397a35f3ce2623e776d2de6a81 275 Pfam PF00491 Arginase family 19 264 3.5E-58 T 31-10-2018 IPR006035 Ureohydrolase GO:0046872 AF_0646 2512c9397a35f3ce2623e776d2de6a81 275 PIRSF PIRSF036979 1 272 2.8E-88 T 31-10-2018 IPR006035 Ureohydrolase GO:0046872 AF_0646 2512c9397a35f3ce2623e776d2de6a81 275 SUPERFAMILY SSF52768 3 268 7.92E-67 T 31-10-2018 IPR023696 Ureohydrolase domain superfamily AF_0646 2512c9397a35f3ce2623e776d2de6a81 275 Gene3D G3DSA:3.40.800.10 2 272 5.4E-73 T 31-10-2018 AF_0646 2512c9397a35f3ce2623e776d2de6a81 275 TIGRFAM TIGR01230 agmatinase: agmatinase 5 266 2.9E-111 T 31-10-2018 IPR005925 Agmatinase-related KEGG: 00330+3.5.3.11|MetaCyc: PWY-40|MetaCyc: PWY-6305|Reactome: R-HSA-351143 AF_0438 7fe80e0eacfd4a15f762ed5059d9df0d 387 Pfam PF02803 Thiolase, C-terminal domain 259 360 7.4E-6 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 AF_0438 7fe80e0eacfd4a15f762ed5059d9df0d 387 SUPERFAMILY SSF53901 228 384 2.27E-27 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0438 7fe80e0eacfd4a15f762ed5059d9df0d 387 PIRSF PIRSF000429 1 385 9.6E-63 T 31-10-2018 IPR002155 Thiolase GO:0016747 AF_0438 7fe80e0eacfd4a15f762ed5059d9df0d 387 Gene3D G3DSA:3.40.47.10 2 387 1.8E-124 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0438 7fe80e0eacfd4a15f762ed5059d9df0d 387 SUPERFAMILY SSF53901 3 229 3.02E-48 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0438 7fe80e0eacfd4a15f762ed5059d9df0d 387 Pfam PF00108 Thiolase, N-terminal domain 14 222 6.1E-28 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 PRINTS PR00980 Alanyl-tRNA synthetase signature 338 354 1.3E-18 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 PRINTS PR00980 Alanyl-tRNA synthetase signature 208 219 1.3E-18 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 PRINTS PR00980 Alanyl-tRNA synthetase signature 242 255 1.3E-18 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 PRINTS PR00980 Alanyl-tRNA synthetase signature 130 141 1.3E-18 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 PRINTS PR00980 Alanyl-tRNA synthetase signature 362 375 1.3E-18 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 Pfam PF02272 DHHA1 domain 769 896 5.8E-18 T 31-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 Gene3D G3DSA:3.30.980.10 598 734 3.2E-47 T 31-10-2018 AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 Pfam PF01411 tRNA synthetases class II (A) 64 591 5.1E-149 T 31-10-2018 IPR018164 Alanyl-tRNA synthetase, class IIc, N-terminal GO:0000166|GO:0004813|GO:0005524|GO:0006419 KEGG: 00970+6.1.1.7 AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 TIGRFAM TIGR00344 alaS: alanine--tRNA ligase 64 883 1.7E-272 T 31-10-2018 IPR002318 Alanine-tRNA ligase, class IIc GO:0000166|GO:0005737 KEGG: 00970+6.1.1.7 AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 SUPERFAMILY SSF50447 502 587 2.08E-17 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 TIGRFAM TIGR03683 A-tRNA_syn_arch: alanine--tRNA ligase 6 901 0.0 T 31-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 SUPERFAMILY SSF55681 61 261 2.15E-55 T 31-10-2018 AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 Pfam PF07973 Threonyl and Alanyl tRNA synthetase second additional domain 691 732 3.0E-14 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 Gene3D G3DSA:3.30.930.10 1 257 7.4E-117 T 31-10-2018 AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 Gene3D G3DSA:2.40.30.130 491 588 8.5E-35 T 31-10-2018 AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 SUPERFAMILY SSF55186 588 745 8.37E-45 T 31-10-2018 IPR018163 Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily GO:0000166 AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 SUPERFAMILY SSF101353 309 517 1.12E-41 T 31-10-2018 IPR018162 Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily GO:0000166|GO:0004813|GO:0005524|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 Gene3D G3DSA:3.30.54.20 660 714 3.2E-47 T 31-10-2018 AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 SMART SM00863 691 733 3.6E-18 T 31-10-2018 IPR012947 Threonyl/alanyl tRNA synthetase, SAD GO:0004812|GO:0005524|GO:0043039 AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 Hamap MF_00036_A Alanine--tRNA ligase [alaS]. 7 898 23.335 T 31-10-2018 IPR022429 Alanine-tRNA ligase, archaea GO:0000166|GO:0005737|GO:0006419 KEGG: 00970+6.1.1.7 AF_2255 af2b1b69d2304279dac1344dd2f0d654 906 Gene3D G3DSA:3.10.310.40 801 906 7.0E-42 T 31-10-2018 AF_0265 f8ee80af23043817b0d38edb51d64ec2 170 SMART SM00852 14 162 2.0E-20 T 31-10-2018 IPR001453 MoaB/Mog domain AF_0265 f8ee80af23043817b0d38edb51d64ec2 170 Pfam PF00994 Probable molybdopterin binding domain 14 161 2.3E-34 T 31-10-2018 IPR001453 MoaB/Mog domain AF_0265 f8ee80af23043817b0d38edb51d64ec2 170 PIRSF PIRSF006443 2 170 1.3E-57 T 31-10-2018 IPR012245 Molybdenum cofactor biosynthesis protein MoaB GO:0006777 AF_0265 f8ee80af23043817b0d38edb51d64ec2 170 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 11 156 4.2E-37 T 31-10-2018 IPR001453 MoaB/Mog domain AF_0265 f8ee80af23043817b0d38edb51d64ec2 170 SUPERFAMILY SSF53218 11 167 7.98E-36 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily AF_0265 f8ee80af23043817b0d38edb51d64ec2 170 Gene3D G3DSA:3.40.980.10 6 170 2.7E-42 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily AF_1639 254cf16be3f15aac08c031ed10e9d009 323 Gene3D G3DSA:3.30.450.20 4 126 7.3E-13 T 31-10-2018 AF_1639 254cf16be3f15aac08c031ed10e9d009 323 SMART SM00388 126 187 5.0E-7 T 31-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AF_1639 254cf16be3f15aac08c031ed10e9d009 323 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 3 119 1.7E-13 T 31-10-2018 IPR000014 PAS domain AF_1639 254cf16be3f15aac08c031ed10e9d009 323 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 221 318 1.9E-21 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_1639 254cf16be3f15aac08c031ed10e9d009 323 SUPERFAMILY SSF47384 113 181 9.61E-6 T 31-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AF_1639 254cf16be3f15aac08c031ed10e9d009 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 253 267 2.0E-12 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1639 254cf16be3f15aac08c031ed10e9d009 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 271 281 2.0E-12 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1639 254cf16be3f15aac08c031ed10e9d009 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 304 317 2.0E-12 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1639 254cf16be3f15aac08c031ed10e9d009 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 281 299 2.0E-12 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1639 254cf16be3f15aac08c031ed10e9d009 323 SUPERFAMILY SSF55785 13 121 2.62E-13 T 31-10-2018 IPR035965 PAS domain superfamily AF_1639 254cf16be3f15aac08c031ed10e9d009 323 SMART SM00387 218 320 1.7E-28 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_1639 254cf16be3f15aac08c031ed10e9d009 323 Pfam PF00989 PAS fold 4 110 4.6E-7 T 31-10-2018 IPR013767 PAS fold GO:0006355 AF_1639 254cf16be3f15aac08c031ed10e9d009 323 Gene3D G3DSA:3.30.565.10 185 317 1.6E-28 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_1639 254cf16be3f15aac08c031ed10e9d009 323 Gene3D G3DSA:1.10.287.130 134 184 1.6E-28 T 31-10-2018 AF_1639 254cf16be3f15aac08c031ed10e9d009 323 SUPERFAMILY SSF55874 187 320 8.25E-25 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_0838 6b859b38b87b3f36960d90187d87c8af 436 Gene3D G3DSA:3.40.50.720 2 133 2.7E-39 T 31-10-2018 AF_0838 6b859b38b87b3f36960d90187d87c8af 436 Pfam PF02080 TrkA-C domain 369 435 1.4E-17 T 31-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AF_0838 6b859b38b87b3f36960d90187d87c8af 436 Pfam PF02080 TrkA-C domain 150 218 1.4E-16 T 31-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AF_0838 6b859b38b87b3f36960d90187d87c8af 436 Gene3D G3DSA:3.30.70.1450 135 219 4.6E-22 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AF_0838 6b859b38b87b3f36960d90187d87c8af 436 SUPERFAMILY SSF116726 365 435 2.09E-15 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AF_0838 6b859b38b87b3f36960d90187d87c8af 436 Pfam PF02254 TrkA-N domain 226 341 8.5E-23 T 31-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AF_0838 6b859b38b87b3f36960d90187d87c8af 436 Pfam PF02254 TrkA-N domain 3 103 2.0E-24 T 31-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AF_0838 6b859b38b87b3f36960d90187d87c8af 436 Gene3D G3DSA:3.40.50.720 223 356 3.4E-33 T 31-10-2018 AF_0838 6b859b38b87b3f36960d90187d87c8af 436 PRINTS PR00335 TrkA potassium uptake protein signature 18 32 2.9E-14 T 31-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 AF_0838 6b859b38b87b3f36960d90187d87c8af 436 PRINTS PR00335 TrkA potassium uptake protein signature 2 16 2.9E-14 T 31-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 AF_0838 6b859b38b87b3f36960d90187d87c8af 436 PRINTS PR00335 TrkA potassium uptake protein signature 58 68 2.9E-14 T 31-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 AF_0838 6b859b38b87b3f36960d90187d87c8af 436 PRINTS PR00335 TrkA potassium uptake protein signature 47 57 2.9E-14 T 31-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 AF_0838 6b859b38b87b3f36960d90187d87c8af 436 PRINTS PR00335 TrkA potassium uptake protein signature 71 85 2.9E-14 T 31-10-2018 IPR006036 Potassium uptake protein TrkA GO:0005886|GO:0006813|GO:0015079 AF_0838 6b859b38b87b3f36960d90187d87c8af 436 SUPERFAMILY SSF51735 222 364 7.46E-28 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0838 6b859b38b87b3f36960d90187d87c8af 436 Gene3D G3DSA:3.30.70.1450 357 436 1.8E-21 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AF_0838 6b859b38b87b3f36960d90187d87c8af 436 SUPERFAMILY SSF116726 131 218 3.14E-18 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AF_0838 6b859b38b87b3f36960d90187d87c8af 436 SUPERFAMILY SSF51735 1 147 1.24E-32 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1938 4657b6c4eb13315d2f2aef19479828a8 673 SUPERFAMILY SSF52210 348 505 2.88E-34 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1938 4657b6c4eb13315d2f2aef19479828a8 673 Pfam PF13549 ATP-grasp domain 2 205 4.9E-63 T 31-10-2018 AF_1938 4657b6c4eb13315d2f2aef19479828a8 673 Pfam PF13380 CoA binding domain 225 350 9.7E-25 T 31-10-2018 IPR003781 CoA-binding GO:0048037 AF_1938 4657b6c4eb13315d2f2aef19479828a8 673 Gene3D G3DSA:3.30.470.20 3 203 3.8E-72 T 31-10-2018 AF_1938 4657b6c4eb13315d2f2aef19479828a8 673 SUPERFAMILY SSF56059 1 208 1.94E-43 T 31-10-2018 AF_1938 4657b6c4eb13315d2f2aef19479828a8 673 Gene3D G3DSA:3.40.50.720 216 345 1.1E-48 T 31-10-2018 AF_1938 4657b6c4eb13315d2f2aef19479828a8 673 SUPERFAMILY SSF52210 511 668 1.83E-22 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1938 4657b6c4eb13315d2f2aef19479828a8 673 SUPERFAMILY SSF51735 215 354 5.03E-40 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1938 4657b6c4eb13315d2f2aef19479828a8 673 Gene3D G3DSA:3.40.50.261 346 508 2.1E-47 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1938 4657b6c4eb13315d2f2aef19479828a8 673 Gene3D G3DSA:3.30.1490.20 21 91 3.8E-72 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AF_1938 4657b6c4eb13315d2f2aef19479828a8 673 Gene3D G3DSA:3.40.50.261 509 672 4.6E-32 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1938 4657b6c4eb13315d2f2aef19479828a8 673 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 368 505 7.5E-46 T 31-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain AF_1938 4657b6c4eb13315d2f2aef19479828a8 673 SMART SM00881 221 316 6.1E-42 T 31-10-2018 IPR003781 CoA-binding GO:0048037 AF_0793 02acb8450b8dc114055fad9707d13b1c 207 Pfam PF04893 Yip1 domain 3 190 7.1E-24 T 31-10-2018 IPR006977 Yip1 domain GO:0016020 AF_1515 383a7f2fd41fa22c0b6190c69d1d8709 338 SMART SM00387 224 326 3.7E-32 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_1515 383a7f2fd41fa22c0b6190c69d1d8709 338 SUPERFAMILY SSF47384 120 187 7.06E-5 T 31-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AF_1515 383a7f2fd41fa22c0b6190c69d1d8709 338 SUPERFAMILY SSF55785 8 113 5.41E-10 T 31-10-2018 IPR035965 PAS domain superfamily AF_1515 383a7f2fd41fa22c0b6190c69d1d8709 338 Gene3D G3DSA:1.10.287.130 139 190 4.1E-33 T 31-10-2018 AF_1515 383a7f2fd41fa22c0b6190c69d1d8709 338 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 227 325 3.5E-23 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_1515 383a7f2fd41fa22c0b6190c69d1d8709 338 SUPERFAMILY SSF55874 220 323 2.1E-28 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_1515 383a7f2fd41fa22c0b6190c69d1d8709 338 Gene3D G3DSA:3.30.565.10 191 323 4.1E-33 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_1515 383a7f2fd41fa22c0b6190c69d1d8709 338 Gene3D G3DSA:3.30.450.20 2 116 1.5E-9 T 31-10-2018 AF_1515 383a7f2fd41fa22c0b6190c69d1d8709 338 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 7 124 1.2E-10 T 31-10-2018 IPR000014 PAS domain AF_1515 383a7f2fd41fa22c0b6190c69d1d8709 338 SMART SM00388 132 193 5.7E-6 T 31-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AF_1515 383a7f2fd41fa22c0b6190c69d1d8709 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 288 306 3.4E-10 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1515 383a7f2fd41fa22c0b6190c69d1d8709 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 260 274 3.4E-10 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1515 383a7f2fd41fa22c0b6190c69d1d8709 338 PRINTS PR00344 Bacterial sensor protein C-terminal signature 278 288 3.4E-10 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1592 eff9bb8c08a871e1ee03256fe653a160 251 SUPERFAMILY SSF75615 144 236 2.51E-6 T 31-10-2018 AF_1592 eff9bb8c08a871e1ee03256fe653a160 251 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 35 62 - T 31-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 AF_1592 eff9bb8c08a871e1ee03256fe653a160 251 TIGRFAM TIGR01470 cysG_Nterm: siroheme synthase, N-terminal domain 24 232 6.3E-19 T 31-10-2018 IPR006367 Sirohaem synthase, N-terminal GO:0006779|GO:0019354|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AF_1592 eff9bb8c08a871e1ee03256fe653a160 251 SUPERFAMILY SSF51735 24 130 1.2E-20 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1592 eff9bb8c08a871e1ee03256fe653a160 251 Gene3D G3DSA:3.40.50.720 24 154 2.3E-24 T 31-10-2018 AF_1592 eff9bb8c08a871e1ee03256fe653a160 251 Pfam PF13241 Putative NAD(P)-binding 26 138 1.8E-20 T 31-10-2018 AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 571 701 4.2E-47 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 234 363 1.3E-50 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 ProSitePatterns PS00674 AAA-protein family signature. 672 690 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 Gene3D G3DSA:1.10.8.60 441 524 9.6E-20 T 31-10-2018 AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 SMART SM01073 8 92 8.6E-40 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 Gene3D G3DSA:3.40.50.300 529 790 3.2E-109 T 31-10-2018 AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 Gene3D G3DSA:2.40.40.20 1 92 1.3E-34 T 31-10-2018 AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 ProSitePatterns PS00674 AAA-protein family signature. 334 352 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 8 91 2.6E-32 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 SUPERFAMILY SSF52540 529 792 8.54E-80 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 SMART SM01072 109 185 8.4E-16 T 31-10-2018 IPR004201 CDC48, domain 2 AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 SUPERFAMILY SSF50692 3 91 1.49E-29 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 Gene3D G3DSA:1.10.8.60 703 775 3.2E-109 T 31-10-2018 AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 Pfam PF09336 Vps4 C terminal oligomerisation domain 756 792 5.0E-5 T 31-10-2018 IPR015415 Vps4 oligomerisation, C-terminal AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 Gene3D G3DSA:1.10.8.60 365 386 3.5E-79 T 31-10-2018 AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 SUPERFAMILY SSF54585 93 199 1.5E-19 T 31-10-2018 IPR029067 CDC48 domain 2-like superfamily AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 Gene3D G3DSA:3.10.330.10 93 179 1.8E-7 T 31-10-2018 AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 7 794 0.0 T 31-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 SUPERFAMILY SSF52540 194 522 4.8E-70 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 SMART SM00382 567 704 1.5E-24 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 SMART SM00382 230 366 4.8E-26 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 110 184 9.2E-17 T 31-10-2018 IPR004201 CDC48, domain 2 AF_2098 522f31d0994705f37e263ddc9e9baa6c 811 Gene3D G3DSA:3.40.50.300 194 364 3.5E-79 T 31-10-2018 AF_0832 30728a50be89595c7ced3512359404c1 188 SUPERFAMILY SSF47240 2 139 1.8E-30 T 31-10-2018 IPR009078 Ferritin-like superfamily AF_0832 30728a50be89595c7ced3512359404c1 188 Gene3D G3DSA:2.20.28.10 143 184 1.2E-12 T 31-10-2018 AF_0832 30728a50be89595c7ced3512359404c1 188 SUPERFAMILY SSF57802 144 182 5.26E-10 T 31-10-2018 AF_0832 30728a50be89595c7ced3512359404c1 188 Gene3D G3DSA:1.20.1260.10 1 142 1.1E-36 T 31-10-2018 IPR012347 Ferritin-like AF_0832 30728a50be89595c7ced3512359404c1 188 Pfam PF02915 Rubrerythrin 5 135 3.4E-30 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 AF_1396 b0f90be3e1502e84d04298d1b1c110f5 162 SUPERFAMILY SSF64288 2 159 7.85E-45 T 31-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AF_1396 b0f90be3e1502e84d04298d1b1c110f5 162 Gene3D G3DSA:3.40.1410.10 1 162 1.3E-56 T 31-10-2018 IPR028978 Chorismate pyruvate-lyase/UbiC transcription regulator-associated domain superfamily AF_1396 b0f90be3e1502e84d04298d1b1c110f5 162 Pfam PF01947 Protein of unknown function (DUF98) 9 160 5.2E-42 T 31-10-2018 IPR002800 Chorismate pyruvate-lyase Rv2949c-like AF_0275 747d4c0a3471ff7ae759caa249a5fbe5 914 Pfam PF10342 Ser-Thr-rich glycosyl-phosphatidyl-inositol-anchored membrane family 259 341 5.1E-11 T 31-10-2018 IPR018466 Kre9/Knh1 family AF_0275 747d4c0a3471ff7ae759caa249a5fbe5 914 Gene3D G3DSA:2.160.20.10 3 172 2.7E-8 T 31-10-2018 IPR012334 Pectin lyase fold AF_0275 747d4c0a3471ff7ae759caa249a5fbe5 914 SMART SM00710 110 131 1700.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_0275 747d4c0a3471ff7ae759caa249a5fbe5 914 SMART SM00710 65 87 1300.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_0275 747d4c0a3471ff7ae759caa249a5fbe5 914 SMART SM00710 144 167 5200.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_0275 747d4c0a3471ff7ae759caa249a5fbe5 914 SMART SM00710 43 64 61.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_0275 747d4c0a3471ff7ae759caa249a5fbe5 914 SMART SM00710 88 109 130.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_0275 747d4c0a3471ff7ae759caa249a5fbe5 914 Pfam PF05048 Periplasmic copper-binding protein (NosD) 44 239 9.5E-27 T 31-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AF_0275 747d4c0a3471ff7ae759caa249a5fbe5 914 TIGRFAM TIGR04126 PGF_CTERM: PGF-CTERM archaeal protein-sorting signal 891 914 6.9E-8 T 31-10-2018 IPR026371 PGF-CTERM archaeal protein-sorting signal AF_0275 747d4c0a3471ff7ae759caa249a5fbe5 914 SUPERFAMILY SSF51126 2 201 2.09E-13 T 31-10-2018 IPR011050 Pectin lyase fold/virulence factor AF_0275 747d4c0a3471ff7ae759caa249a5fbe5 914 SMART SM00722 61 232 3.7E-7 T 31-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain AF_0855 e58ec64bf7cc9f9b1608527191f9c1e6 294 Pfam PF02866 lactate/malate dehydrogenase, alpha/beta C-terminal domain 146 291 2.3E-21 T 31-10-2018 IPR022383 Lactate/malate dehydrogenase, C-terminal GO:0016616|GO:0055114 AF_0855 e58ec64bf7cc9f9b1608527191f9c1e6 294 PIRSF PIRSF000102 1 294 3.6E-94 T 31-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AF_0855 e58ec64bf7cc9f9b1608527191f9c1e6 294 ProSitePatterns PS00064 L-lactate dehydrogenase active site. 169 175 - T 31-10-2018 IPR018177 L-lactate dehydrogenase, active site GO:0004459|GO:0055114 KEGG: 00010+1.1.1.27|KEGG: 00270+1.1.1.27|KEGG: 00620+1.1.1.27|KEGG: 00640+1.1.1.27|MetaCyc: PWY-5481|MetaCyc: PWY-6901|Reactome: R-HSA-70268 AF_0855 e58ec64bf7cc9f9b1608527191f9c1e6 294 Gene3D G3DSA:3.40.50.720 1 142 2.9E-56 T 31-10-2018 AF_0855 e58ec64bf7cc9f9b1608527191f9c1e6 294 PRINTS PR00086 L-lactate dehydrogenase signature 2 26 5.0E-33 T 31-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AF_0855 e58ec64bf7cc9f9b1608527191f9c1e6 294 PRINTS PR00086 L-lactate dehydrogenase signature 115 135 5.0E-33 T 31-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AF_0855 e58ec64bf7cc9f9b1608527191f9c1e6 294 PRINTS PR00086 L-lactate dehydrogenase signature 27 51 5.0E-33 T 31-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AF_0855 e58ec64bf7cc9f9b1608527191f9c1e6 294 PRINTS PR00086 L-lactate dehydrogenase signature 167 180 5.0E-33 T 31-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AF_0855 e58ec64bf7cc9f9b1608527191f9c1e6 294 PRINTS PR00086 L-lactate dehydrogenase signature 139 157 5.0E-33 T 31-10-2018 IPR001557 L-lactate/malate dehydrogenase GO:0016616|GO:0019752|GO:0055114 AF_0855 e58ec64bf7cc9f9b1608527191f9c1e6 294 SUPERFAMILY SSF56327 143 292 1.31E-40 T 31-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 AF_0855 e58ec64bf7cc9f9b1608527191f9c1e6 294 Pfam PF00056 lactate/malate dehydrogenase, NAD binding domain 2 141 3.3E-40 T 31-10-2018 IPR001236 Lactate/malate dehydrogenase, N-terminal GO:0016491|GO:0055114 AF_0855 e58ec64bf7cc9f9b1608527191f9c1e6 294 Gene3D G3DSA:3.90.110.10 143 294 1.7E-43 T 31-10-2018 IPR015955 Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal GO:0003824|GO:0005975|GO:0016616|GO:0055114 AF_0855 e58ec64bf7cc9f9b1608527191f9c1e6 294 SUPERFAMILY SSF51735 1 142 2.79E-46 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0765 7230d0bd211cebb2c2fcae669cadbca7 71 Gene3D G3DSA:2.40.50.140 4 70 1.5E-28 T 31-10-2018 AF_0765 7230d0bd211cebb2c2fcae669cadbca7 71 Pfam PF01200 Ribosomal protein S28e 5 68 2.1E-30 T 31-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0765 7230d0bd211cebb2c2fcae669cadbca7 71 SUPERFAMILY SSF50249 4 69 3.68E-25 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0765 7230d0bd211cebb2c2fcae669cadbca7 71 ProSitePatterns PS00961 Ribosomal protein S28e signature. 60 68 - T 31-10-2018 IPR028626 Ribosomal protein S28e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0765 7230d0bd211cebb2c2fcae669cadbca7 71 Hamap MF_00292 30S ribosomal protein S28e [rps28e]. 1 69 25.085 T 31-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0765 7230d0bd211cebb2c2fcae669cadbca7 71 ProDom PD005541 RIBOSOMAL RIBONUCLEOPROTEIN 40S S28 S28E 30S ACETYLATION S33 S33 CG15527 7 51 1.0E-18 T 31-10-2018 IPR000289 Ribosomal protein S28e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1274 deff0afc9c584452e540efd623f9d934 1076 SUPERFAMILY SSF52440 558 677 1.34E-51 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AF_1274 deff0afc9c584452e540efd623f9d934 1076 Gene3D G3DSA:3.30.470.20 668 937 6.9E-121 T 31-10-2018 AF_1274 deff0afc9c584452e540efd623f9d934 1076 Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain 425 549 3.3E-44 T 31-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_1274 deff0afc9c584452e540efd623f9d934 1076 SMART SM00851 958 1044 5.7E-29 T 31-10-2018 IPR011607 Methylglyoxal synthase-like domain AF_1274 deff0afc9c584452e540efd623f9d934 1076 Gene3D G3DSA:3.30.470.20 120 402 8.7E-129 T 31-10-2018 AF_1274 deff0afc9c584452e540efd623f9d934 1076 ProSitePatterns PS00867 Carbamoyl-phosphate synthase subdomain signature 2. 840 847 - T 31-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AF_1274 deff0afc9c584452e540efd623f9d934 1076 SUPERFAMILY SSF52335 937 1074 3.79E-36 T 31-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AF_1274 deff0afc9c584452e540efd623f9d934 1076 SUPERFAMILY SSF56059 128 400 1.4E-111 T 31-10-2018 AF_1274 deff0afc9c584452e540efd623f9d934 1076 SUPERFAMILY SSF48108 395 555 2.35E-52 T 31-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_1274 deff0afc9c584452e540efd623f9d934 1076 SUPERFAMILY SSF56059 675 935 3.54E-109 T 31-10-2018 AF_1274 deff0afc9c584452e540efd623f9d934 1076 TIGRFAM TIGR01369 CPSaseII_lrg: carbamoyl-phosphate synthase, large subunit 2 1055 0.0 T 31-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_1274 deff0afc9c584452e540efd623f9d934 1076 SMART SM01096 422 549 5.6E-70 T 31-10-2018 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_1274 deff0afc9c584452e540efd623f9d934 1076 Gene3D G3DSA:3.40.50.20 1 116 4.0E-50 T 31-10-2018 AF_1274 deff0afc9c584452e540efd623f9d934 1076 Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. 5 1072 14.993 T 31-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_1274 deff0afc9c584452e540efd623f9d934 1076 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 164 178 - T 31-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AF_1274 deff0afc9c584452e540efd623f9d934 1076 Gene3D G3DSA:3.40.50.1380 938 1076 2.9E-43 T 31-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AF_1274 deff0afc9c584452e540efd623f9d934 1076 SUPERFAMILY SSF52440 1 127 2.45E-50 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AF_1274 deff0afc9c584452e540efd623f9d934 1076 Gene3D G3DSA:3.40.50.20 556 664 5.4E-51 T 31-10-2018 AF_1274 deff0afc9c584452e540efd623f9d934 1076 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 711 725 - T 31-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AF_1274 deff0afc9c584452e540efd623f9d934 1076 Gene3D G3DSA:1.10.1030.10 407 555 8.9E-52 T 31-10-2018 IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_1274 deff0afc9c584452e540efd623f9d934 1076 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 675 877 2.6E-39 T 31-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AF_1274 deff0afc9c584452e540efd623f9d934 1076 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 128 334 2.2E-73 T 31-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AF_1274 deff0afc9c584452e540efd623f9d934 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 168 180 8.7E-67 T 31-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_1274 deff0afc9c584452e540efd623f9d934 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 297 326 8.7E-67 T 31-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_1274 deff0afc9c584452e540efd623f9d934 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 19 33 8.7E-67 T 31-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_1274 deff0afc9c584452e540efd623f9d934 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 239 256 8.7E-67 T 31-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_1274 deff0afc9c584452e540efd623f9d934 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 48 58 8.7E-67 T 31-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_1274 deff0afc9c584452e540efd623f9d934 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 204 223 8.7E-67 T 31-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_1274 deff0afc9c584452e540efd623f9d934 1076 PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature 379 397 8.7E-67 T 31-10-2018 IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_1274 deff0afc9c584452e540efd623f9d934 1076 Pfam PF02142 MGS-like domain 959 1044 4.2E-20 T 31-10-2018 IPR011607 Methylglyoxal synthase-like domain AF_1274 deff0afc9c584452e540efd623f9d934 1076 Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. 1 1065 13.434 T 31-10-2018 IPR006275 Carbamoyl-phosphate synthase, large subunit GO:0006807 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_0767 c0989273457f66761c46b6b8cab8d3b6 151 Pfam PF00334 Nucleoside diphosphate kinase 2 136 1.1E-61 T 31-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AF_0767 c0989273457f66761c46b6b8cab8d3b6 151 ProSitePatterns PS00469 Nucleoside diphosphate kinases active site. 112 120 - T 31-10-2018 IPR023005 Nucleoside diphosphate kinase, active site KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AF_0767 c0989273457f66761c46b6b8cab8d3b6 151 SMART SM00562 1 138 2.5E-98 T 31-10-2018 IPR034907 Nucleoside diphosphate kinase-like domain KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AF_0767 c0989273457f66761c46b6b8cab8d3b6 151 Hamap MF_00451 Nucleoside diphosphate kinase [ndk]. 1 136 39.677 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AF_0767 c0989273457f66761c46b6b8cab8d3b6 151 PRINTS PR01243 Nucleoside diphosphate kinase signature 112 131 5.0E-52 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AF_0767 c0989273457f66761c46b6b8cab8d3b6 151 PRINTS PR01243 Nucleoside diphosphate kinase signature 89 105 5.0E-52 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AF_0767 c0989273457f66761c46b6b8cab8d3b6 151 PRINTS PR01243 Nucleoside diphosphate kinase signature 68 85 5.0E-52 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AF_0767 c0989273457f66761c46b6b8cab8d3b6 151 PRINTS PR01243 Nucleoside diphosphate kinase signature 4 26 5.0E-52 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AF_0767 c0989273457f66761c46b6b8cab8d3b6 151 PRINTS PR01243 Nucleoside diphosphate kinase signature 48 67 5.0E-52 T 31-10-2018 IPR001564 Nucleoside diphosphate kinase GO:0004550|GO:0006165|GO:0006183|GO:0006228|GO:0006241 KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AF_0767 c0989273457f66761c46b6b8cab8d3b6 151 SUPERFAMILY SSF54919 1 149 1.27E-66 T 31-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AF_0767 c0989273457f66761c46b6b8cab8d3b6 151 Gene3D G3DSA:3.30.70.141 1 151 1.1E-70 T 31-10-2018 IPR036850 Nucleoside diphosphate kinase-like domain superfamily KEGG: 00230+2.7.4.6|KEGG: 00240+2.7.4.6|KEGG: 00983+2.7.4.6|MetaCyc: PWY-6545|MetaCyc: PWY-7176|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7205|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7221|MetaCyc: PWY-7222|MetaCyc: PWY-7224|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AF_1344 e541f59055bc2e457556e2b504d9479f 292 Hamap MF_00902 Sec-independent protein translocase protein TatC [tatC]. 2 289 12.251 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AF_1344 e541f59055bc2e457556e2b504d9479f 292 Pfam PF00902 Sec-independent protein translocase protein (TatC) 10 272 2.8E-46 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AF_1344 e541f59055bc2e457556e2b504d9479f 292 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 154 180 7.6E-8 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AF_1344 e541f59055bc2e457556e2b504d9479f 292 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 205 233 7.6E-8 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AF_0269 a122d2359f0c14a4192211f2f2c87057 61 ProDom PD052877 ARCHAEL AF0269 4 44 3.0E-17 T 31-10-2018 AF_1740 5a060a092083fbc6503d50d44e59b29d 179 Hamap MF_01117 CDP-archaeol synthase [carS]. 12 179 27.929 T 31-10-2018 IPR002726 CDP-archaeol synthase, archaea KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 AF_1740 5a060a092083fbc6503d50d44e59b29d 179 Pfam PF01864 CDP-archaeol synthase 1 179 5.1E-88 T 31-10-2018 IPR032690 CDP-archaeol synthase KEGG: 00564+2.7.7.67|MetaCyc: PWY-6349 AF_1242 54a028a64f231388baeaba085a8b100d 289 SUPERFAMILY SSF54782 212 285 1.57E-11 T 31-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AF_1242 54a028a64f231388baeaba085a8b100d 289 Pfam PF01379 Porphobilinogen deaminase, dipyromethane cofactor binding domain 3 207 2.2E-70 T 31-10-2018 IPR022417 Porphobilinogen deaminase, N-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AF_1242 54a028a64f231388baeaba085a8b100d 289 Gene3D G3DSA:3.40.190.10 97 197 9.6E-74 T 31-10-2018 AF_1242 54a028a64f231388baeaba085a8b100d 289 Gene3D G3DSA:3.30.160.40 213 289 3.4E-7 T 31-10-2018 IPR036803 Porphobilinogen deaminase, C-terminal domain superfamily GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AF_1242 54a028a64f231388baeaba085a8b100d 289 PIRSF PIRSF001438 1 288 1.3E-99 T 31-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AF_1242 54a028a64f231388baeaba085a8b100d 289 Pfam PF03900 Porphobilinogen deaminase, C-terminal domain 217 287 7.9E-18 T 31-10-2018 IPR022418 Porphobilinogen deaminase, C-terminal GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AF_1242 54a028a64f231388baeaba085a8b100d 289 ProSitePatterns PS00533 Porphobilinogen deaminase cofactor-binding site. 223 239 - T 31-10-2018 IPR022419 Porphobilinogen deaminase, dipyrromethane cofactor binding site GO:0004418|GO:0018160|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AF_1242 54a028a64f231388baeaba085a8b100d 289 SUPERFAMILY SSF53850 1 211 1.43E-70 T 31-10-2018 AF_1242 54a028a64f231388baeaba085a8b100d 289 Gene3D G3DSA:3.40.190.10 4 205 9.6E-74 T 31-10-2018 AF_1242 54a028a64f231388baeaba085a8b100d 289 TIGRFAM TIGR00212 hemC: hydroxymethylbilane synthase 3 285 1.1E-93 T 31-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AF_1242 54a028a64f231388baeaba085a8b100d 289 PRINTS PR00151 Porphobilinogen deaminase signature 222 239 9.7E-36 T 31-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AF_1242 54a028a64f231388baeaba085a8b100d 289 PRINTS PR00151 Porphobilinogen deaminase signature 137 154 9.7E-36 T 31-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AF_1242 54a028a64f231388baeaba085a8b100d 289 PRINTS PR00151 Porphobilinogen deaminase signature 118 135 9.7E-36 T 31-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AF_1242 54a028a64f231388baeaba085a8b100d 289 PRINTS PR00151 Porphobilinogen deaminase signature 70 89 9.7E-36 T 31-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AF_1242 54a028a64f231388baeaba085a8b100d 289 PRINTS PR00151 Porphobilinogen deaminase signature 39 59 9.7E-36 T 31-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AF_1242 54a028a64f231388baeaba085a8b100d 289 Hamap MF_00260 Porphobilinogen deaminase [hemC]. 2 289 35.515 T 31-10-2018 IPR000860 Porphobilinogen deaminase GO:0004418|GO:0033014 KEGG: 00860+2.5.1.61|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AF_1913 83dfccddb2c2b9108aec588f1d93239e 235 Gene3D G3DSA:2.30.30.30 169 226 1.7E-21 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 AF_1913 83dfccddb2c2b9108aec588f1d93239e 235 PIRSF PIRSF002116 1 234 3.4E-91 T 31-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1913 83dfccddb2c2b9108aec588f1d93239e 235 SUPERFAMILY SSF55174 47 91 1.26E-7 T 31-10-2018 AF_1913 83dfccddb2c2b9108aec588f1d93239e 235 Pfam PF08071 RS4NT (NUC023) domain 5 36 8.8E-13 T 31-10-2018 IPR013843 Ribosomal protein S4e, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1913 83dfccddb2c2b9108aec588f1d93239e 235 SMART SM00739 167 194 0.0019 T 31-10-2018 IPR005824 KOW AF_1913 83dfccddb2c2b9108aec588f1d93239e 235 SMART SM00363 39 102 0.0038 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1913 83dfccddb2c2b9108aec588f1d93239e 235 Pfam PF01479 S4 domain 47 86 3.7E-10 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1913 83dfccddb2c2b9108aec588f1d93239e 235 Gene3D G3DSA:3.10.290.40 2 112 3.5E-40 T 31-10-2018 AF_1913 83dfccddb2c2b9108aec588f1d93239e 235 Pfam PF00900 Ribosomal family S4e 92 162 3.1E-21 T 31-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1913 83dfccddb2c2b9108aec588f1d93239e 235 Gene3D G3DSA:2.40.50.740 116 167 1.8E-19 T 31-10-2018 IPR038237 Ribosomal protein S4e, central domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1913 83dfccddb2c2b9108aec588f1d93239e 235 Hamap MF_00485 30S ribosomal protein S4e [rps4e]. 4 233 40.505 T 31-10-2018 IPR000876 Ribosomal protein S4e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1913 83dfccddb2c2b9108aec588f1d93239e 235 ProDom PD002667 RIBOSOMAL RIBONUCLEOPROTEIN RNA-BINDING 40S S4 S4 S4E 30S ISOFORM X 84 173 1.0E-44 T 31-10-2018 IPR013845 Ribosomal protein S4e, central region Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1913 83dfccddb2c2b9108aec588f1d93239e 235 ProSitePatterns PS00528 Ribosomal protein S4e signature. 5 19 - T 31-10-2018 IPR018199 Ribosomal protein S4e, N-terminal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2224 596c8fd59b31557472c5c83a3285f66d 863 Gene3D G3DSA:3.90.740.10 172 334 4.4E-251 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AF_2224 596c8fd59b31557472c5c83a3285f66d 863 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 31-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_2224 596c8fd59b31557472c5c83a3285f66d 863 SUPERFAMILY SSF47323 569 774 2.06E-55 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_2224 596c8fd59b31557472c5c83a3285f66d 863 Gene3D G3DSA:3.40.50.620 23 518 4.4E-251 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_2224 596c8fd59b31557472c5c83a3285f66d 863 Gene3D G3DSA:1.10.730.10 4 729 4.4E-251 T 31-10-2018 AF_2224 596c8fd59b31557472c5c83a3285f66d 863 SUPERFAMILY SSF50677 192 333 2.75E-46 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AF_2224 596c8fd59b31557472c5c83a3285f66d 863 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 15 553 3.0E-145 T 31-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_2224 596c8fd59b31557472c5c83a3285f66d 863 TIGRFAM TIGR00422 valS: valine--tRNA ligase 4 840 0.0 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AF_2224 596c8fd59b31557472c5c83a3285f66d 863 SUPERFAMILY SSF52374 4 566 1.26E-135 T 31-10-2018 AF_2224 596c8fd59b31557472c5c83a3285f66d 863 Hamap MF_02005 Valine--tRNA ligase [valS]. 3 767 29.843 T 31-10-2018 IPR022874 Valine-tRNA ligase, type 2 GO:0004832 KEGG: 00970+6.1.1.9 AF_2224 596c8fd59b31557472c5c83a3285f66d 863 PRINTS PR00986 Valyl-tRNA synthetase signature 36 47 1.9E-24 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AF_2224 596c8fd59b31557472c5c83a3285f66d 863 PRINTS PR00986 Valyl-tRNA synthetase signature 337 350 1.9E-24 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AF_2224 596c8fd59b31557472c5c83a3285f66d 863 PRINTS PR00986 Valyl-tRNA synthetase signature 469 487 1.9E-24 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AF_2224 596c8fd59b31557472c5c83a3285f66d 863 PRINTS PR00986 Valyl-tRNA synthetase signature 443 464 1.9E-24 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AF_2224 596c8fd59b31557472c5c83a3285f66d 863 PRINTS PR00986 Valyl-tRNA synthetase signature 222 239 1.9E-24 T 31-10-2018 IPR002303 Valine-tRNA ligase GO:0000166|GO:0004832|GO:0005524|GO:0006438 KEGG: 00970+6.1.1.9 AF_2224 596c8fd59b31557472c5c83a3285f66d 863 Pfam PF08264 Anticodon-binding domain of tRNA 598 743 1.9E-43 T 31-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AF_0813 c63e8b20280e914471166b48a5b5cdb8 527 Pfam PF01842 ACT domain 454 517 1.1E-14 T 31-10-2018 IPR002912 ACT domain AF_0813 c63e8b20280e914471166b48a5b5cdb8 527 Gene3D G3DSA:3.40.50.720 92 282 3.6E-127 T 31-10-2018 AF_0813 c63e8b20280e914471166b48a5b5cdb8 527 SUPERFAMILY SSF52283 1 134 3.97E-42 T 31-10-2018 AF_0813 c63e8b20280e914471166b48a5b5cdb8 527 SUPERFAMILY SSF51735 99 281 1.51E-63 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0813 c63e8b20280e914471166b48a5b5cdb8 527 Gene3D G3DSA:3.30.1330.90 321 451 1.7E-33 T 31-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 AF_0813 c63e8b20280e914471166b48a5b5cdb8 527 Gene3D G3DSA:3.30.70.260 452 527 7.7E-16 T 31-10-2018 AF_0813 c63e8b20280e914471166b48a5b5cdb8 527 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 219 235 - T 31-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AF_0813 c63e8b20280e914471166b48a5b5cdb8 527 SUPERFAMILY SSF143548 319 447 8.89E-33 T 31-10-2018 IPR029009 Allosteric substrate binding domain superfamily Reactome: R-HSA-977347 AF_0813 c63e8b20280e914471166b48a5b5cdb8 527 Gene3D G3DSA:3.40.50.720 3 291 3.6E-127 T 31-10-2018 AF_0813 c63e8b20280e914471166b48a5b5cdb8 527 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 105 280 9.4E-68 T 31-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AF_0813 c63e8b20280e914471166b48a5b5cdb8 527 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 449 520 6.0E-6 T 31-10-2018 AF_0813 c63e8b20280e914471166b48a5b5cdb8 527 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 190 212 - T 31-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AF_0813 c63e8b20280e914471166b48a5b5cdb8 527 SUPERFAMILY SSF55021 444 525 3.6E-18 T 31-10-2018 AF_0813 c63e8b20280e914471166b48a5b5cdb8 527 TIGRFAM TIGR01327 PGDH: phosphoglycerate dehydrogenase 2 527 1.1E-233 T 31-10-2018 IPR006236 D-3-phosphoglycerate dehydrogenase GO:0004617|GO:0006564 KEGG: 00260+1.1.1.95|KEGG: 00680+1.1.1.95|Reactome: R-HSA-977347 AF_0813 c63e8b20280e914471166b48a5b5cdb8 527 ProSitePatterns PS00065 D-isomer specific 2-hydroxyacid dehydrogenases NAD-binding signature. 142 169 - T 31-10-2018 IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 AF_0813 c63e8b20280e914471166b48a5b5cdb8 527 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 3 312 2.5E-44 T 31-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 AF_2085 e6181c785d95dc0971b3f1571c51c26f 142 Pfam PF00364 Biotin-requiring enzyme 66 138 1.7E-21 T 31-10-2018 IPR000089 Biotin/lipoyl attachment AF_2085 e6181c785d95dc0971b3f1571c51c26f 142 Gene3D G3DSA:2.40.50.100 65 138 1.1E-24 T 31-10-2018 AF_2085 e6181c785d95dc0971b3f1571c51c26f 142 SUPERFAMILY SSF51230 67 138 3.27E-23 T 31-10-2018 IPR011053 Single hybrid motif AF_1179 92afbe5518ee50cfb2ee6781608c30c7 315 Gene3D G3DSA:3.10.270.10 14 296 7.9E-73 T 31-10-2018 AF_1179 92afbe5518ee50cfb2ee6781608c30c7 315 Pfam PF02649 Type I GTP cyclohydrolase folE2 2 291 3.7E-78 T 31-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 AF_1179 92afbe5518ee50cfb2ee6781608c30c7 315 Hamap MF_01527_A GTP cyclohydrolase FolE2 [folE2]. 1 295 38.482 T 31-10-2018 IPR022840 GTP cyclohydrolase MptA GO:0003933 KEGG: 00790+3.5.4.39|MetaCyc: PWY-6797|MetaCyc: PWY-7853 AF_1179 92afbe5518ee50cfb2ee6781608c30c7 315 TIGRFAM TIGR00294 TIGR00294: GTP cyclohydrolase 4 308 7.1E-151 T 31-10-2018 IPR003801 GTP cyclohydrolase FolE2/MptA GO:0003933 KEGG: 00790+3.5.4.16|MetaCyc: PWY-5663|MetaCyc: PWY-5664|MetaCyc: PWY-6147|MetaCyc: PWY-6703|MetaCyc: PWY-6983|MetaCyc: PWY-7442|MetaCyc: PWY-7852 AF_0091 b2cd24e7654219d353af7f8596f24f96 324 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 108 321 2.8E-63 T 31-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 AF_0091 b2cd24e7654219d353af7f8596f24f96 324 SUPERFAMILY SSF56529 109 322 8.5E-69 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AF_0091 b2cd24e7654219d353af7f8596f24f96 324 Gene3D G3DSA:3.90.850.10 37 315 1.2E-75 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AF_0950 f926f9c3a4cfeebbb59f579e06e9b30f 157 Pfam PF13247 4Fe-4S dicluster domain 66 150 4.0E-18 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0950 f926f9c3a4cfeebbb59f579e06e9b30f 157 Gene3D G3DSA:3.30.70.20 15 150 4.5E-30 T 31-10-2018 AF_0950 f926f9c3a4cfeebbb59f579e06e9b30f 157 Gene3D G3DSA:3.30.70.20 74 126 4.5E-30 T 31-10-2018 AF_0950 f926f9c3a4cfeebbb59f579e06e9b30f 157 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 100 111 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0950 f926f9c3a4cfeebbb59f579e06e9b30f 157 SUPERFAMILY SSF54862 6 151 1.04E-41 T 31-10-2018 AF_0675 aa14bcd66589e2dac2c5634e5ebf32ab 238 Pfam PF12146 Serine aminopeptidase, S33 36 119 4.6E-10 T 31-10-2018 IPR022742 Serine aminopeptidase, S33 AF_0675 aa14bcd66589e2dac2c5634e5ebf32ab 238 Gene3D G3DSA:3.40.50.1820 9 235 4.5E-36 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_0675 aa14bcd66589e2dac2c5634e5ebf32ab 238 SUPERFAMILY SSF53474 19 230 4.5E-34 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_1879 513b52f058d42d0c6dd87be982cd0cdc 281 PIRSF PIRSF009226 6 281 2.5E-110 T 31-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 AF_1879 513b52f058d42d0c6dd87be982cd0cdc 281 TIGRFAM TIGR01896 cas_AF1879: CRISPR-associated protein Cas4/Csa1, subtype I-A/APERN 21 280 4.2E-61 T 31-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 AF_1879 513b52f058d42d0c6dd87be982cd0cdc 281 Pfam PF06023 CRISPR-associated exonuclease Csa1 1 280 2.1E-111 T 31-10-2018 IPR009260 CRISPR-associated exonuclease Csa1 AF_1286 d8e5a18d7c22aeddf30419133883afa8 189 SUPERFAMILY SSF52768 4 188 2.41E-39 T 31-10-2018 IPR023696 Ureohydrolase domain superfamily AF_1286 d8e5a18d7c22aeddf30419133883afa8 189 Pfam PF00850 Histone deacetylase domain 2 69 3.0E-19 T 31-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_1286 d8e5a18d7c22aeddf30419133883afa8 189 Gene3D G3DSA:3.40.800.20 1 189 3.0E-39 T 31-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_1286 d8e5a18d7c22aeddf30419133883afa8 189 PRINTS PR01270 Histone deacetylase superfamily signature 16 39 4.0E-13 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_1286 d8e5a18d7c22aeddf30419133883afa8 189 PRINTS PR01270 Histone deacetylase superfamily signature 50 65 4.0E-13 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_1286 d8e5a18d7c22aeddf30419133883afa8 189 PRINTS PR01270 Histone deacetylase superfamily signature 118 128 4.0E-13 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_1286 d8e5a18d7c22aeddf30419133883afa8 189 Pfam PF00850 Histone deacetylase domain 100 184 4.0E-8 T 31-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_2273 2f49493202f7eca5007834286c64cb0f 668 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 200 294 3.4E-31 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_2273 2f49493202f7eca5007834286c64cb0f 668 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 320 387 2.7E-12 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_2273 2f49493202f7eca5007834286c64cb0f 668 SUPERFAMILY SSF52096 408 668 8.36E-86 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AF_2273 2f49493202f7eca5007834286c64cb0f 668 Pfam PF00378 Enoyl-CoA hydratase/isomerase 419 667 1.2E-59 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AF_2273 2f49493202f7eca5007834286c64cb0f 668 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 508 528 - T 31-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 AF_2273 2f49493202f7eca5007834286c64cb0f 668 Gene3D G3DSA:3.40.50.720 6 201 2.0E-73 T 31-10-2018 AF_2273 2f49493202f7eca5007834286c64cb0f 668 SUPERFAMILY SSF48179 199 312 6.55E-31 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_2273 2f49493202f7eca5007834286c64cb0f 668 SUPERFAMILY SSF51735 16 196 5.76E-62 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_2273 2f49493202f7eca5007834286c64cb0f 668 Gene3D G3DSA:1.10.1040.10 312 398 9.1E-36 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AF_2273 2f49493202f7eca5007834286c64cb0f 668 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 19 197 2.2E-68 T 31-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_2273 2f49493202f7eca5007834286c64cb0f 668 Gene3D G3DSA:1.10.1040.10 202 311 4.4E-32 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AF_2273 2f49493202f7eca5007834286c64cb0f 668 Gene3D G3DSA:3.90.226.10 399 608 1.1E-72 T 31-10-2018 AF_2273 2f49493202f7eca5007834286c64cb0f 668 SUPERFAMILY SSF48179 317 387 1.02E-13 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_2273 2f49493202f7eca5007834286c64cb0f 668 Gene3D G3DSA:1.10.12.10 609 667 3.8E-19 T 31-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AF_1399 d504013f5f521f0bd899b3c25dee0bff 613 Gene3D G3DSA:2.130.10.10 267 386 5.2E-27 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AF_1399 d504013f5f521f0bd899b3c25dee0bff 613 SUPERFAMILY SSF50998 13 275 4.71E-29 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AF_1399 d504013f5f521f0bd899b3c25dee0bff 613 Pfam PF13360 PQQ-like domain 80 204 2.2E-10 T 31-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AF_1399 d504013f5f521f0bd899b3c25dee0bff 613 Pfam PF13360 PQQ-like domain 245 374 2.1E-17 T 31-10-2018 IPR002372 Pyrrolo-quinoline quinone repeat AF_1399 d504013f5f521f0bd899b3c25dee0bff 613 SMART SM00564 188 222 83.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AF_1399 d504013f5f521f0bd899b3c25dee0bff 613 SMART SM00564 355 385 210.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AF_1399 d504013f5f521f0bd899b3c25dee0bff 613 SMART SM00564 268 298 0.65 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AF_1399 d504013f5f521f0bd899b3c25dee0bff 613 SMART SM00564 231 260 5.8 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AF_1399 d504013f5f521f0bd899b3c25dee0bff 613 SMART SM00564 102 133 0.097 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AF_1399 d504013f5f521f0bd899b3c25dee0bff 613 SMART SM00564 307 340 1.4E-6 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AF_1399 d504013f5f521f0bd899b3c25dee0bff 613 SMART SM00564 146 178 4.1E-4 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AF_1399 d504013f5f521f0bd899b3c25dee0bff 613 SMART SM00564 56 94 150.0 T 31-10-2018 IPR018391 Pyrrolo-quinoline quinone beta-propeller repeat AF_1399 d504013f5f521f0bd899b3c25dee0bff 613 SUPERFAMILY SSF50998 218 384 8.79E-30 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AF_1399 d504013f5f521f0bd899b3c25dee0bff 613 Gene3D G3DSA:2.40.128.630 30 137 1.2E-9 T 31-10-2018 AF_1399 d504013f5f521f0bd899b3c25dee0bff 613 Gene3D G3DSA:2.130.10.10 140 266 3.4E-21 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AF_1399 d504013f5f521f0bd899b3c25dee0bff 613 Gene3D G3DSA:3.10.20.490 397 490 2.7E-5 T 31-10-2018 AF_0937 408da73977ed25066fcb5f16d17f6f43 423 TIGRFAM TIGR00483 EF-1_alpha: translation elongation factor EF-1, subunit alpha 1 423 3.1E-256 T 31-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 AF_0937 408da73977ed25066fcb5f16d17f6f43 423 SUPERFAMILY SSF50447 222 312 1.54E-31 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AF_0937 408da73977ed25066fcb5f16d17f6f43 423 Pfam PF03143 Elongation factor Tu C-terminal domain 313 418 3.1E-37 T 31-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal AF_0937 408da73977ed25066fcb5f16d17f6f43 423 Gene3D G3DSA:2.40.30.10 221 313 1.0E-39 T 31-10-2018 AF_0937 408da73977ed25066fcb5f16d17f6f43 423 Gene3D G3DSA:3.40.50.300 1 215 6.0E-90 T 31-10-2018 AF_0937 408da73977ed25066fcb5f16d17f6f43 423 Gene3D G3DSA:2.40.30.10 314 419 6.9E-42 T 31-10-2018 AF_0937 408da73977ed25066fcb5f16d17f6f43 423 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 7 193 6.6E-18 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AF_0937 408da73977ed25066fcb5f16d17f6f43 423 SUPERFAMILY SSF52540 3 240 4.76E-79 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0937 408da73977ed25066fcb5f16d17f6f43 423 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 61 76 - T 31-10-2018 IPR031157 Tr-type G domain, conserved site AF_0937 408da73977ed25066fcb5f16d17f6f43 423 Pfam PF03144 Elongation factor Tu domain 2 239 304 5.5E-18 T 31-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AF_0937 408da73977ed25066fcb5f16d17f6f43 423 Hamap MF_00118_A Elongation factor Tu [tuf]. 2 422 62.323 T 31-10-2018 IPR004539 Translation elongation factor EF1A, eukaryotic/archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 Reactome: R-HSA-156842 AF_0937 408da73977ed25066fcb5f16d17f6f43 423 Pfam PF00009 Elongation factor Tu GTP binding domain 5 213 4.8E-60 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_0937 408da73977ed25066fcb5f16d17f6f43 423 SUPERFAMILY SSF50465 315 419 3.6E-39 T 31-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal AF_0937 408da73977ed25066fcb5f16d17f6f43 423 PRINTS PR00315 GTP-binding elongation factor signature 104 115 2.3E-24 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_0937 408da73977ed25066fcb5f16d17f6f43 423 PRINTS PR00315 GTP-binding elongation factor signature 88 98 2.3E-24 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_0937 408da73977ed25066fcb5f16d17f6f43 423 PRINTS PR00315 GTP-binding elongation factor signature 141 150 2.3E-24 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_0937 408da73977ed25066fcb5f16d17f6f43 423 PRINTS PR00315 GTP-binding elongation factor signature 9 22 2.3E-24 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_0937 408da73977ed25066fcb5f16d17f6f43 423 PRINTS PR00315 GTP-binding elongation factor signature 68 76 2.3E-24 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_2149 2008a6611f23d3ab538d727379c6e7c5 211 SUPERFAMILY SSF109755 16 197 3.49E-6 T 31-10-2018 AF_2149 2008a6611f23d3ab538d727379c6e7c5 211 Pfam PF01865 Protein of unknown function DUF47 7 208 1.6E-67 T 31-10-2018 IPR018445 Putative phosphate transport regulator AF_2149 2008a6611f23d3ab538d727379c6e7c5 211 Gene3D G3DSA:1.20.58.220 9 207 1.0E-28 T 31-10-2018 IPR038078 PhoU-like domain superfamily AF_2149 2008a6611f23d3ab538d727379c6e7c5 211 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 2 211 9.0E-81 T 31-10-2018 IPR002727 Protein of unknown function DUF47 AF_0659 7b16558d2884d9a7e42b2e954715219b 511 Gene3D G3DSA:3.40.50.300 231 511 1.7E-117 T 31-10-2018 AF_0659 7b16558d2884d9a7e42b2e954715219b 511 Pfam PF00437 Type II/IV secretion system protein 134 380 2.5E-50 T 31-10-2018 IPR001482 Type II/IV secretion system protein AF_0659 7b16558d2884d9a7e42b2e954715219b 511 SUPERFAMILY SSF52540 114 492 1.87E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0659 7b16558d2884d9a7e42b2e954715219b 511 Gene3D G3DSA:3.30.450.380 1 230 4.6E-102 T 31-10-2018 AF_0299 0d289b60ecce447eddea72ce7d07550b 102 SUPERFAMILY SSF81301 2 101 1.47E-18 T 31-10-2018 AF_0299 0d289b60ecce447eddea72ce7d07550b 102 Pfam PF01909 Nucleotidyltransferase domain 7 100 2.0E-16 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AF_0299 0d289b60ecce447eddea72ce7d07550b 102 Gene3D G3DSA:3.30.460.10 1 99 2.7E-19 T 31-10-2018 AF_1415 a9b07d6babddc335ab4bc6153037da46 589 Gene3D G3DSA:1.10.3080.10 9 456 1.8E-104 T 31-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 AF_1415 a9b07d6babddc335ab4bc6153037da46 589 Pfam PF00571 CBS domain 467 511 1.2E-6 T 31-10-2018 IPR000644 CBS domain AF_1415 a9b07d6babddc335ab4bc6153037da46 589 Pfam PF00571 CBS domain 524 579 1.7E-16 T 31-10-2018 IPR000644 CBS domain AF_1415 a9b07d6babddc335ab4bc6153037da46 589 Gene3D G3DSA:3.10.580.10 457 586 2.8E-29 T 31-10-2018 AF_1415 a9b07d6babddc335ab4bc6153037da46 589 SMART SM00116 531 581 4.7E-12 T 31-10-2018 IPR000644 CBS domain AF_1415 a9b07d6babddc335ab4bc6153037da46 589 SMART SM00116 469 516 6.2E-6 T 31-10-2018 IPR000644 CBS domain AF_1415 a9b07d6babddc335ab4bc6153037da46 589 SUPERFAMILY SSF81340 11 446 1.15E-104 T 31-10-2018 IPR014743 Chloride channel, core Reactome: R-HSA-2672351 AF_1415 a9b07d6babddc335ab4bc6153037da46 589 SUPERFAMILY SSF54631 448 582 8.46E-31 T 31-10-2018 AF_1415 a9b07d6babddc335ab4bc6153037da46 589 PRINTS PR00762 Chloride channel signature 378 394 3.3E-22 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AF_1415 a9b07d6babddc335ab4bc6153037da46 589 PRINTS PR00762 Chloride channel signature 343 363 3.3E-22 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AF_1415 a9b07d6babddc335ab4bc6153037da46 589 PRINTS PR00762 Chloride channel signature 396 415 3.3E-22 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AF_1415 a9b07d6babddc335ab4bc6153037da46 589 PRINTS PR00762 Chloride channel signature 120 139 3.3E-22 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AF_1415 a9b07d6babddc335ab4bc6153037da46 589 PRINTS PR00762 Chloride channel signature 171 190 3.3E-22 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AF_1415 a9b07d6babddc335ab4bc6153037da46 589 Pfam PF00654 Voltage gated chloride channel 77 428 4.3E-98 T 31-10-2018 IPR001807 Chloride channel, voltage gated GO:0005247|GO:0006821|GO:0016020|GO:0055085 Reactome: R-HSA-2672351 AF_1496 90aeb12a02aba0e9a4bbaf1a0e89bf21 353 Pfam PF05559 Protein of unknown function (DUF763) 5 308 2.9E-119 T 31-10-2018 IPR008482 Protein of unknown function DUF763 AF_0535 be9f6d274f31b859a2dc068050b56f73 368 SMART SM00864 44 235 7.9E-107 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AF_0535 be9f6d274f31b859a2dc068050b56f73 368 SMART SM00865 237 354 1.5E-50 T 31-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 AF_0535 be9f6d274f31b859a2dc068050b56f73 368 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 45 204 6.2E-45 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AF_0535 be9f6d274f31b859a2dc068050b56f73 368 PRINTS PR00423 Cell division protein FtsZ signature 219 241 1.8E-44 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AF_0535 be9f6d274f31b859a2dc068050b56f73 368 PRINTS PR00423 Cell division protein FtsZ signature 242 263 1.8E-44 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AF_0535 be9f6d274f31b859a2dc068050b56f73 368 PRINTS PR00423 Cell division protein FtsZ signature 157 178 1.8E-44 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AF_0535 be9f6d274f31b859a2dc068050b56f73 368 PRINTS PR00423 Cell division protein FtsZ signature 129 149 1.8E-44 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AF_0535 be9f6d274f31b859a2dc068050b56f73 368 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 40 363 38.233 T 31-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 AF_0535 be9f6d274f31b859a2dc068050b56f73 368 ProSitePatterns PS01135 FtsZ protein signature 2. 128 149 - T 31-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 AF_0535 be9f6d274f31b859a2dc068050b56f73 368 Gene3D G3DSA:3.40.50.1440 35 250 6.4E-80 T 31-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AF_0535 be9f6d274f31b859a2dc068050b56f73 368 ProSitePatterns PS01134 FtsZ protein signature 1. 75 109 - T 31-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 AF_0535 be9f6d274f31b859a2dc068050b56f73 368 Pfam PF12327 FtsZ family, C-terminal domain 252 346 7.3E-39 T 31-10-2018 IPR024757 Cell division protein FtsZ, C-terminal AF_0535 be9f6d274f31b859a2dc068050b56f73 368 SUPERFAMILY SSF52490 44 238 7.98E-67 T 31-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AF_0535 be9f6d274f31b859a2dc068050b56f73 368 SUPERFAMILY SSF55307 237 352 3.89E-42 T 31-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 AF_0535 be9f6d274f31b859a2dc068050b56f73 368 Gene3D G3DSA:3.30.1330.20 255 360 6.2E-36 T 31-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 AF_0535 be9f6d274f31b859a2dc068050b56f73 368 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 30 356 1.4E-144 T 31-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 AF_1534 928a525807cac136e8a948f4c07e97f6 116 Pfam PF02036 SCP-2 sterol transfer family 9 108 1.0E-15 T 31-10-2018 IPR003033 SCP2 sterol-binding domain AF_1534 928a525807cac136e8a948f4c07e97f6 116 Gene3D G3DSA:3.30.1050.10 1 116 1.1E-41 T 31-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AF_1534 928a525807cac136e8a948f4c07e97f6 116 SUPERFAMILY SSF55718 5 110 3.77E-23 T 31-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AF_0473 52cd2a79a5051ee4458d27790f16df73 804 Pfam PF00122 E1-E2 ATPase 222 400 2.4E-58 T 31-10-2018 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 Gene3D G3DSA:2.70.150.20 214 326 1.3E-45 T 31-10-2018 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 140 726 9.9E-184 T 31-10-2018 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 SUPERFAMILY SSF55008 14 82 4.71E-20 T 31-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 Gene3D G3DSA:3.40.50.1000 403 668 1.1E-109 T 31-10-2018 IPR023214 HAD superfamily AF_0473 52cd2a79a5051ee4458d27790f16df73 804 Pfam PF00403 Heavy-metal-associated domain 19 79 1.0E-14 T 31-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 Pfam PF00403 Heavy-metal-associated domain 744 799 5.8E-5 T 31-10-2018 IPR006121 Heavy metal-associated domain, HMA GO:0030001|GO:0046872 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 422 436 4.6E-27 T 31-10-2018 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 542 553 4.6E-27 T 31-10-2018 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 564 574 4.6E-27 T 31-10-2018 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 639 651 4.6E-27 T 31-10-2018 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 271 285 4.6E-27 T 31-10-2018 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 616 635 4.6E-27 T 31-10-2018 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 SUPERFAMILY SSF81653 225 321 3.27E-30 T 31-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 Gene3D G3DSA:3.40.1110.10 433 549 1.1E-109 T 31-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 Pfam PF00702 haloacid dehalogenase-like hydrolase 419 630 2.1E-43 T 31-10-2018 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 Gene3D G3DSA:3.30.70.100 15 81 1.6E-21 T 31-10-2018 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 SUPERFAMILY SSF81665 187 689 1.96E-15 T 31-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 SUPERFAMILY SSF55008 741 802 1.83E-9 T 31-10-2018 IPR036163 Heavy metal-associated domain superfamily GO:0030001|GO:0046872 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 SUPERFAMILY SSF56784 421 723 3.79E-58 T 31-10-2018 IPR036412 HAD-like superfamily AF_0473 52cd2a79a5051ee4458d27790f16df73 804 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 194 694 1.2E-100 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 ProSitePatterns PS01047 Heavy-metal-associated domain. 746 774 - T 31-10-2018 IPR017969 Heavy-metal-associated, conserved site GO:0030001|GO:0046872 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 Gene3D G3DSA:3.30.70.100 741 804 7.3E-16 T 31-10-2018 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 TIGRFAM TIGR00003 TIGR00003: copper ion binding protein 19 81 2.8E-18 T 31-10-2018 IPR006122 Heavy metal-associated domain, copper ion-binding GO:0005507 Reactome: R-HSA-936837 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00943 Copper-transporting ATPase signature 405 420 1.0E-9 T 31-10-2018 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00943 Copper-transporting ATPase signature 191 210 1.0E-9 T 31-10-2018 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00943 Copper-transporting ATPase signature 143 162 1.0E-9 T 31-10-2018 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00943 Copper-transporting ATPase signature 594 611 1.0E-9 T 31-10-2018 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00943 Copper-transporting ATPase signature 650 664 1.0E-9 T 31-10-2018 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00943 Copper-transporting ATPase signature 32 46 1.0E-9 T 31-10-2018 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 PRINTS PR00943 Copper-transporting ATPase signature 344 358 1.0E-9 T 31-10-2018 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 424 430 - T 31-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AF_0473 52cd2a79a5051ee4458d27790f16df73 804 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 158 725 1.1E-191 T 31-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AF_1620 4aad37170325efacab79e05c68614953 781 Gene3D G3DSA:3.30.450.20 281 427 2.2E-36 T 31-10-2018 AF_1620 4aad37170325efacab79e05c68614953 781 Pfam PF00989 PAS fold 433 543 1.3E-19 T 31-10-2018 IPR013767 PAS fold GO:0006355 AF_1620 4aad37170325efacab79e05c68614953 781 Pfam PF13426 PAS domain 205 276 0.0036 T 31-10-2018 IPR000014 PAS domain AF_1620 4aad37170325efacab79e05c68614953 781 Pfam PF13426 PAS domain 300 401 3.1E-16 T 31-10-2018 IPR000014 PAS domain AF_1620 4aad37170325efacab79e05c68614953 781 SUPERFAMILY SSF46785 706 779 1.03E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1620 4aad37170325efacab79e05c68614953 781 SUPERFAMILY SSF55785 278 401 5.24E-29 T 31-10-2018 IPR035965 PAS domain superfamily AF_1620 4aad37170325efacab79e05c68614953 781 SMART SM00091 432 498 1.6E-11 T 31-10-2018 IPR000014 PAS domain AF_1620 4aad37170325efacab79e05c68614953 781 SMART SM00091 289 355 4.9E-12 T 31-10-2018 IPR000014 PAS domain AF_1620 4aad37170325efacab79e05c68614953 781 SMART SM00091 189 251 0.075 T 31-10-2018 IPR000014 PAS domain AF_1620 4aad37170325efacab79e05c68614953 781 Pfam PF00672 HAMP domain 132 178 3.9E-11 T 31-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AF_1620 4aad37170325efacab79e05c68614953 781 Gene3D G3DSA:1.20.1480.50 111 184 3.2E-10 T 31-10-2018 AF_1620 4aad37170325efacab79e05c68614953 781 Pfam PF05763 Protein of unknown function (DUF835) 574 696 1.1E-15 T 31-10-2018 IPR008553 Domain of unknown function DUF835 AF_1620 4aad37170325efacab79e05c68614953 781 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 286 410 2.2E-31 T 31-10-2018 IPR000014 PAS domain AF_1620 4aad37170325efacab79e05c68614953 781 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 432 552 4.6E-30 T 31-10-2018 IPR000014 PAS domain AF_1620 4aad37170325efacab79e05c68614953 781 SMART SM00304 131 182 1.9E-9 T 31-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AF_1620 4aad37170325efacab79e05c68614953 781 SUPERFAMILY SSF55785 443 552 5.59E-26 T 31-10-2018 IPR035965 PAS domain superfamily AF_1620 4aad37170325efacab79e05c68614953 781 SMART SM00086 504 546 2.5E-4 T 31-10-2018 IPR001610 PAC motif AF_1620 4aad37170325efacab79e05c68614953 781 SMART SM00086 361 403 6.0E-5 T 31-10-2018 IPR001610 PAC motif AF_1620 4aad37170325efacab79e05c68614953 781 Gene3D G3DSA:3.30.450.20 185 280 8.6E-6 T 31-10-2018 AF_1620 4aad37170325efacab79e05c68614953 781 Gene3D G3DSA:3.30.450.20 428 564 4.8E-31 T 31-10-2018 AF_1620 4aad37170325efacab79e05c68614953 781 SUPERFAMILY SSF158472 132 179 1.57E-6 T 31-10-2018 AF_1620 4aad37170325efacab79e05c68614953 781 SUPERFAMILY SSF55785 174 278 3.35E-9 T 31-10-2018 IPR035965 PAS domain superfamily AF_1620 4aad37170325efacab79e05c68614953 781 Gene3D G3DSA:1.10.10.10 703 781 6.1E-8 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0287 1e0e30d41c1de522fa5fd20c6975bf14 317 SMART SM00893 3 185 1.3E-36 T 31-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AF_0287 1e0e30d41c1de522fa5fd20c6975bf14 317 SUPERFAMILY SSF52402 1 186 2.3E-40 T 31-10-2018 AF_0287 1e0e30d41c1de522fa5fd20c6975bf14 317 Gene3D G3DSA:3.40.50.620 1 184 1.3E-41 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_0287 1e0e30d41c1de522fa5fd20c6975bf14 317 PIRSF PIRSF000089 1 317 1.2E-107 T 31-10-2018 IPR001308 Electron transfer flavoprotein alpha subunit/FixB GO:0009055|GO:0050660 Reactome: R-HSA-611105 AF_0287 1e0e30d41c1de522fa5fd20c6975bf14 317 SUPERFAMILY SSF52467 192 312 8.18E-47 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AF_0287 1e0e30d41c1de522fa5fd20c6975bf14 317 Pfam PF00766 Electron transfer flavoprotein FAD-binding domain 192 275 5.9E-35 T 31-10-2018 IPR014731 Electron transfer flavoprotein, alpha subunit, C-terminal Reactome: R-HSA-611105 AF_0287 1e0e30d41c1de522fa5fd20c6975bf14 317 Gene3D G3DSA:3.40.50.1220 187 317 2.4E-55 T 31-10-2018 AF_0287 1e0e30d41c1de522fa5fd20c6975bf14 317 Pfam PF01012 Electron transfer flavoprotein domain 11 169 9.5E-37 T 31-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AF_0113 9d359e59753109edbca9b8977de3ebaf 359 PIRSF PIRSF004602 2 359 2.7E-154 T 31-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 AF_0113 9d359e59753109edbca9b8977de3ebaf 359 Pfam PF06849 Protein of unknown function (DUF1246) 22 141 6.9E-46 T 31-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 AF_0113 9d359e59753109edbca9b8977de3ebaf 359 Hamap MF_01163 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase [purP]. 20 359 52.576 T 31-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 AF_0113 9d359e59753109edbca9b8977de3ebaf 359 Pfam PF06973 Domain of unknown function (DUF1297) 172 358 8.0E-76 T 31-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 AF_0113 9d359e59753109edbca9b8977de3ebaf 359 Gene3D G3DSA:3.30.1490.20 138 201 1.2E-97 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AF_0113 9d359e59753109edbca9b8977de3ebaf 359 Gene3D G3DSA:3.30.470.20 110 358 1.2E-97 T 31-10-2018 AF_0113 9d359e59753109edbca9b8977de3ebaf 359 SUPERFAMILY SSF56059 125 358 2.95E-77 T 31-10-2018 AF_0113 9d359e59753109edbca9b8977de3ebaf 359 Gene3D G3DSA:3.40.50.20 3 107 3.2E-37 T 31-10-2018 AF_0113 9d359e59753109edbca9b8977de3ebaf 359 SUPERFAMILY SSF52440 5 120 1.73E-41 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AF_1710 096442b708f0d613b63e046955141be0 341 Gene3D G3DSA:1.10.287.1120 80 330 4.8E-95 T 31-10-2018 AF_1710 096442b708f0d613b63e046955141be0 341 SUPERFAMILY SSF116734 129 336 3.6E-53 T 31-10-2018 AF_1710 096442b708f0d613b63e046955141be0 341 Gene3D G3DSA:3.90.220.20 144 287 4.8E-95 T 31-10-2018 AF_1710 096442b708f0d613b63e046955141be0 341 SUPERFAMILY SSF116734 1 130 1.64E-35 T 31-10-2018 AF_1710 096442b708f0d613b63e046955141be0 341 Pfam PF01420 Type I restriction modification DNA specificity domain 140 319 3.6E-40 T 31-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 AF_1710 096442b708f0d613b63e046955141be0 341 Pfam PF01420 Type I restriction modification DNA specificity domain 1 102 5.9E-29 T 31-10-2018 IPR000055 Restriction endonuclease, type I, HsdS GO:0003677|GO:0006304 AF_1710 096442b708f0d613b63e046955141be0 341 Gene3D G3DSA:3.90.220.20 1 334 4.8E-95 T 31-10-2018 AF_0845 5ef575ad955efdb31c3f80075d03301f 381 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 229 375 1.4E-54 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AF_0845 5ef575ad955efdb31c3f80075d03301f 381 PIRSF PIRSF016578 6 378 2.4E-24 T 31-10-2018 AF_0845 5ef575ad955efdb31c3f80075d03301f 381 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 7 117 4.3E-37 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AF_0845 5ef575ad955efdb31c3f80075d03301f 381 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 123 135 - T 31-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AF_0845 5ef575ad955efdb31c3f80075d03301f 381 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 334 353 - T 31-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AF_0845 5ef575ad955efdb31c3f80075d03301f 381 SUPERFAMILY SSF47203 225 378 4.19E-61 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AF_0845 5ef575ad955efdb31c3f80075d03301f 381 Gene3D G3DSA:1.10.540.10 1 117 2.9E-41 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AF_0845 5ef575ad955efdb31c3f80075d03301f 381 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 121 215 3.6E-26 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AF_0845 5ef575ad955efdb31c3f80075d03301f 381 Gene3D G3DSA:2.40.110.10 120 232 3.9E-38 T 31-10-2018 AF_0845 5ef575ad955efdb31c3f80075d03301f 381 SUPERFAMILY SSF56645 1 238 7.07E-82 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AF_0845 5ef575ad955efdb31c3f80075d03301f 381 Gene3D G3DSA:1.20.140.10 233 380 6.7E-59 T 31-10-2018 AF_0044 a5913b0a2ade9b46c5f76c11f6d2c733 255 Gene3D G3DSA:3.40.50.720 15 221 4.9E-66 T 31-10-2018 AF_0044 a5913b0a2ade9b46c5f76c11f6d2c733 255 Pfam PF16363 GDP-mannose 4,6 dehydratase 15 255 8.3E-59 T 31-10-2018 IPR016040 NAD(P)-binding domain AF_0044 a5913b0a2ade9b46c5f76c11f6d2c733 255 SUPERFAMILY SSF51735 6 255 8.6E-50 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0044 a5913b0a2ade9b46c5f76c11f6d2c733 255 Gene3D G3DSA:3.90.25.10 222 255 4.9E-66 T 31-10-2018 AF_1196 5507073a60f657baf2a33c6eeec91fdd 348 Hamap MF_01091 5,10-methylenetetrahydromethanopterin reductase [mer]. 1 348 104.152 T 31-10-2018 IPR019946 5,10-methylenetetrahydromethanopterin reductase GO:0018537|GO:0055114 KEGG: 00680+1.5.98.2|MetaCyc: PWY-7784 AF_1196 5507073a60f657baf2a33c6eeec91fdd 348 SUPERFAMILY SSF51679 1 344 3.79E-72 T 31-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AF_1196 5507073a60f657baf2a33c6eeec91fdd 348 Gene3D G3DSA:3.20.20.30 1 346 1.0E-93 T 31-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AF_1196 5507073a60f657baf2a33c6eeec91fdd 348 Pfam PF00296 Luciferase-like monooxygenase 11 319 1.1E-63 T 31-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AF_1912 c0ec2f1020eff33abc80bdbda6a2d24f 178 ProSitePatterns PS00358 Ribosomal protein L5 signature. 44 60 - T 31-10-2018 IPR020929 Ribosomal protein L5, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1912 c0ec2f1020eff33abc80bdbda6a2d24f 178 SUPERFAMILY SSF55282 14 171 3.06E-51 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1912 c0ec2f1020eff33abc80bdbda6a2d24f 178 PIRSF PIRSF002161 1 175 1.0E-52 T 31-10-2018 IPR002132 Ribosomal protein L5 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1912 c0ec2f1020eff33abc80bdbda6a2d24f 178 Hamap MF_01333_A 50S ribosomal protein L5 [rplE]. 13 178 38.029 T 31-10-2018 IPR022804 Ribosomal protein L5, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1912 c0ec2f1020eff33abc80bdbda6a2d24f 178 Gene3D G3DSA:3.30.1440.10 6 178 2.4E-65 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1912 c0ec2f1020eff33abc80bdbda6a2d24f 178 Pfam PF00281 Ribosomal protein L5 14 67 5.1E-19 T 31-10-2018 IPR031310 Ribosomal protein L5, N-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1912 c0ec2f1020eff33abc80bdbda6a2d24f 178 Pfam PF00673 ribosomal L5P family C-terminus 72 168 1.3E-20 T 31-10-2018 IPR031309 Ribosomal protein L5, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1220 bd1f5e450467dca7e54e86419f3d7951 407 SUPERFAMILY SSF55315 267 403 4.45E-40 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like AF_1220 bd1f5e450467dca7e54e86419f3d7951 407 SUPERFAMILY SSF55481 5 132 5.75E-48 T 31-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1220 bd1f5e450467dca7e54e86419f3d7951 407 Hamap MF_00424 Peptide chain release factor subunit 1 [prf1]. 16 404 45.711 T 31-10-2018 IPR020918 Peptide chain release factor aRF1 GO:0003747|GO:0005737|GO:0006415 AF_1220 bd1f5e450467dca7e54e86419f3d7951 407 Pfam PF03465 eRF1 domain 3 270 402 4.0E-36 T 31-10-2018 IPR005142 eRF1 domain 3 AF_1220 bd1f5e450467dca7e54e86419f3d7951 407 SMART SM01194 1 132 4.0E-45 T 31-10-2018 IPR005140 eRF1 domain 1/Pelota-like AF_1220 bd1f5e450467dca7e54e86419f3d7951 407 TIGRFAM TIGR03676 aRF1/eRF1: peptide chain release factor 1, archaeal and eukaryotic forms 6 402 6.5E-183 T 31-10-2018 IPR004403 Peptide chain release factor eRF1/aRF1 GO:0003747|GO:0005737|GO:0006415 Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1220 bd1f5e450467dca7e54e86419f3d7951 407 Gene3D G3DSA:3.30.960.10 1 133 2.0E-48 T 31-10-2018 IPR024049 Peptide Chain Release Factor eRF1/aRF1, N-terminal Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1220 bd1f5e450467dca7e54e86419f3d7951 407 Pfam PF03463 eRF1 domain 1 15 130 5.1E-14 T 31-10-2018 IPR005140 eRF1 domain 1/Pelota-like AF_1220 bd1f5e450467dca7e54e86419f3d7951 407 SUPERFAMILY SSF53137 135 265 1.53E-44 T 31-10-2018 AF_1220 bd1f5e450467dca7e54e86419f3d7951 407 Gene3D G3DSA:3.30.420.60 134 266 2.4E-50 T 31-10-2018 AF_1220 bd1f5e450467dca7e54e86419f3d7951 407 Gene3D G3DSA:3.30.1330.30 268 406 2.0E-43 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like AF_1220 bd1f5e450467dca7e54e86419f3d7951 407 Pfam PF03464 eRF1 domain 2 137 267 1.6E-47 T 31-10-2018 IPR005141 eRF1 domain 2 AF_0782 8ef9479829189b71d20bf03ff8eba1c6 122 PIRSF PIRSF019313 1 122 7.6E-51 T 31-10-2018 IPR012426 Uncharacterised protein family SepF-related, archaea AF_0782 8ef9479829189b71d20bf03ff8eba1c6 122 Pfam PF04472 Cell division protein SepF 39 112 2.0E-14 T 31-10-2018 IPR007561 Cell division protein SepF/SepF-related GO:0090529 AF_0782 8ef9479829189b71d20bf03ff8eba1c6 122 Gene3D G3DSA:3.30.110.150 37 122 4.2E-29 T 31-10-2018 IPR038594 SepF-like superfamily AF_2414 0d9291763bcd7f83e19dc1956d70f6d2 229 SUPERFAMILY SSF47413 18 70 2.23E-12 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AF_2414 0d9291763bcd7f83e19dc1956d70f6d2 229 Pfam PF01381 Helix-turn-helix 34 71 2.2E-9 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AF_2414 0d9291763bcd7f83e19dc1956d70f6d2 229 Gene3D G3DSA:1.10.260.40 16 74 3.0E-11 T 31-10-2018 AF_2414 0d9291763bcd7f83e19dc1956d70f6d2 229 PIRSF PIRSF037724 1 229 7.6E-101 T 31-10-2018 IPR017271 Transcription regulator HTH, MJ1545, predicted AF_2414 0d9291763bcd7f83e19dc1956d70f6d2 229 SMART SM00530 23 77 7.1E-11 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AF_0035 f2ac2e512032cc3d865f365b70686d9e 299 Gene3D G3DSA:2.60.120.10 217 299 2.6E-56 T 31-10-2018 IPR014710 RmlC-like jelly roll fold AF_0035 f2ac2e512032cc3d865f365b70686d9e 299 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 104 294 5.0E-46 T 31-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 AF_0035 f2ac2e512032cc3d865f365b70686d9e 299 TIGRFAM TIGR00218 manA: mannose-6-phosphate isomerase, class I 4 106 1.9E-35 T 31-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 AF_0035 f2ac2e512032cc3d865f365b70686d9e 299 Pfam PF01238 Phosphomannose isomerase type I 34 111 1.2E-5 T 31-10-2018 IPR001250 Mannose-6-phosphate isomerase, type I GO:0004476|GO:0005975|GO:0008270 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882|Reactome: R-HSA-4043916|Reactome: R-HSA-446205 AF_0035 f2ac2e512032cc3d865f365b70686d9e 299 Gene3D G3DSA:2.60.120.10 1 216 3.4E-73 T 31-10-2018 IPR014710 RmlC-like jelly roll fold AF_0035 f2ac2e512032cc3d865f365b70686d9e 299 SUPERFAMILY SSF51182 4 293 6.06E-57 T 31-10-2018 IPR011051 RmlC-like cupin domain superfamily AF_0035 f2ac2e512032cc3d865f365b70686d9e 299 PIRSF PIRSF036894 6 296 3.7E-32 T 31-10-2018 IPR014628 Mannose-6-phosphate isomerase, Firmicutes type, short form GO:0004476|GO:0005975 KEGG: 00051+5.3.1.8|KEGG: 00520+5.3.1.8|MetaCyc: PWY-3861|MetaCyc: PWY-3881|MetaCyc: PWY-5659|MetaCyc: PWY-6992|MetaCyc: PWY-7456|MetaCyc: PWY-7586|MetaCyc: PWY-882 AF_1849 e4bace5f4e700f6aec76b51c291285b4 622 SUPERFAMILY SSF56821 7 622 1.28E-176 T 31-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 AF_1849 e4bace5f4e700f6aec76b51c291285b4 622 Pfam PF03063 Prismane/CO dehydrogenase family 48 602 9.4E-138 T 31-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 AF_1849 e4bace5f4e700f6aec76b51c291285b4 622 Gene3D G3DSA:3.40.50.2030 407 619 2.8E-75 T 31-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 AF_1849 e4bace5f4e700f6aec76b51c291285b4 622 TIGRFAM TIGR01702 CO_DH_cata: carbon-monoxide dehydrogenase, catalytic subunit 8 622 6.6E-285 T 31-10-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 AF_1849 e4bace5f4e700f6aec76b51c291285b4 622 Gene3D G3DSA:1.20.1270.30 62 232 1.4E-46 T 31-10-2018 IPR016101 CO dehydrogenase, alpha-bundle GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 AF_1849 e4bace5f4e700f6aec76b51c291285b4 622 Gene3D G3DSA:3.40.50.2030 233 406 4.9E-51 T 31-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 AF_1849 e4bace5f4e700f6aec76b51c291285b4 622 PIRSF PIRSF005023 1 622 1.4E-261 T 31-10-2018 IPR010047 Ni-containing CO dehydrogenase GO:0006091|GO:0016151|GO:0018492|GO:0051539|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 AF_0441 74b4f27d8afc0d7a44e03f360a20d70e 225 Pfam PF04055 Radical SAM superfamily 26 172 1.1E-10 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_0441 74b4f27d8afc0d7a44e03f360a20d70e 225 Hamap MF_00917 7-carboxy-7-deazaguanine synthase [queE]. 3 225 38.369 T 31-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 AF_0441 74b4f27d8afc0d7a44e03f360a20d70e 225 SUPERFAMILY SSF102114 25 192 1.7E-11 T 31-10-2018 AF_0441 74b4f27d8afc0d7a44e03f360a20d70e 225 PIRSF PIRSF000370 1 225 2.2E-33 T 31-10-2018 IPR024924 7-carboxy-7-deazaguanine synthase-like KEGG: 00790+4.3.99.3|MetaCyc: PWY-6703 AF_0441 74b4f27d8afc0d7a44e03f360a20d70e 225 Pfam PF13353 4Fe-4S single cluster domain 13 96 1.6E-8 T 31-10-2018 AF_0441 74b4f27d8afc0d7a44e03f360a20d70e 225 Gene3D G3DSA:3.20.20.70 4 225 6.7E-29 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1040 8a1342a9439bf8526020dee095caf92d 656 SMART SM00387 378 521 2.6E-30 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_1040 8a1342a9439bf8526020dee095caf92d 656 SUPERFAMILY SSF47226 5 120 5.76E-31 T 31-10-2018 IPR036641 HPT domain superfamily GO:0000160 AF_1040 8a1342a9439bf8526020dee095caf92d 656 SMART SM00073 5 100 1.3E-38 T 31-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 AF_1040 8a1342a9439bf8526020dee095caf92d 656 Pfam PF07194 P2 response regulator binding domain 146 222 2.4E-20 T 31-10-2018 IPR010808 Chemotaxis protein CheA, P2 response regulator-binding GO:0000155|GO:0000160|GO:0004673|GO:0006928 AF_1040 8a1342a9439bf8526020dee095caf92d 656 Gene3D G3DSA:3.30.70.1110 142 224 3.3E-15 T 31-10-2018 IPR037052 Chemotaxis protein CheA, P2 response regulator-binding domain superfamily AF_1040 8a1342a9439bf8526020dee095caf92d 656 SUPERFAMILY SSF47384 274 334 7.45E-16 T 31-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AF_1040 8a1342a9439bf8526020dee095caf92d 656 Gene3D G3DSA:1.20.120.160 1 139 4.2E-38 T 31-10-2018 IPR036641 HPT domain superfamily GO:0000160 AF_1040 8a1342a9439bf8526020dee095caf92d 656 Pfam PF01627 Hpt domain 8 96 2.0E-20 T 31-10-2018 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain GO:0000160 AF_1040 8a1342a9439bf8526020dee095caf92d 656 Gene3D G3DSA:2.30.30.40 521 646 3.8E-36 T 31-10-2018 AF_1040 8a1342a9439bf8526020dee095caf92d 656 Pfam PF02895 Signal transducing histidine kinase, homodimeric domain 275 333 4.1E-13 T 31-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 AF_1040 8a1342a9439bf8526020dee095caf92d 656 SUPERFAMILY SSF50341 520 650 2.49E-31 T 31-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 AF_1040 8a1342a9439bf8526020dee095caf92d 656 SUPERFAMILY SSF55874 335 518 1.22E-40 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_1040 8a1342a9439bf8526020dee095caf92d 656 SUPERFAMILY SSF55052 145 223 8.11E-18 T 31-10-2018 IPR035891 CheY-binding domain of CheA AF_1040 8a1342a9439bf8526020dee095caf92d 656 SMART SM00260 513 650 6.9E-45 T 31-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AF_1040 8a1342a9439bf8526020dee095caf92d 656 Gene3D G3DSA:2.40.50.180 544 605 3.8E-36 T 31-10-2018 AF_1040 8a1342a9439bf8526020dee095caf92d 656 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 380 520 8.2E-20 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_1040 8a1342a9439bf8526020dee095caf92d 656 Pfam PF01584 CheW-like domain 527 650 4.4E-24 T 31-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AF_1040 8a1342a9439bf8526020dee095caf92d 656 Gene3D G3DSA:1.10.287.560 274 333 4.8E-20 T 31-10-2018 IPR037006 Histidine kinase CheA-like, homodimeric domain superfamily GO:0000155|GO:0006935 AF_1040 8a1342a9439bf8526020dee095caf92d 656 Gene3D G3DSA:3.30.565.10 334 520 1.6E-61 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_1040 8a1342a9439bf8526020dee095caf92d 656 SMART SM01231 273 333 2.7E-19 T 31-10-2018 IPR004105 Histidine kinase CheA-like, homodimeric domain GO:0000155|GO:0000160|GO:0004673|GO:0005737|GO:0006935 AF_1040 8a1342a9439bf8526020dee095caf92d 656 PRINTS PR00344 Bacterial sensor protein C-terminal signature 505 518 9.7E-15 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1040 8a1342a9439bf8526020dee095caf92d 656 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 437 9.7E-15 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1040 8a1342a9439bf8526020dee095caf92d 656 PRINTS PR00344 Bacterial sensor protein C-terminal signature 481 499 9.7E-15 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1040 8a1342a9439bf8526020dee095caf92d 656 PRINTS PR00344 Bacterial sensor protein C-terminal signature 465 475 9.7E-15 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_2254 5717ab02d9dbac9d288f318f3b07d47d 368 Gene3D G3DSA:3.40.50.300 216 368 6.5E-49 T 31-10-2018 AF_2254 5717ab02d9dbac9d288f318f3b07d47d 368 Gene3D G3DSA:3.40.50.300 2 213 3.1E-79 T 31-10-2018 AF_2254 5717ab02d9dbac9d288f318f3b07d47d 368 ProSitePatterns PS00039 DEAD-box subfamily ATP-dependent helicases signature. 155 163 - T 31-10-2018 IPR000629 ATP-dependent RNA helicase DEAD-box, conserved site AF_2254 5717ab02d9dbac9d288f318f3b07d47d 368 Pfam PF00271 Helicase conserved C-terminal domain 232 339 9.3E-29 T 31-10-2018 IPR001650 Helicase, C-terminal AF_2254 5717ab02d9dbac9d288f318f3b07d47d 368 Pfam PF00270 DEAD/DEAH box helicase 31 195 2.4E-50 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AF_2254 5717ab02d9dbac9d288f318f3b07d47d 368 SMART SM00487 26 223 3.6E-67 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AF_2254 5717ab02d9dbac9d288f318f3b07d47d 368 SUPERFAMILY SSF52540 76 360 1.45E-75 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2254 5717ab02d9dbac9d288f318f3b07d47d 368 SMART SM00490 258 339 1.9E-31 T 31-10-2018 IPR001650 Helicase, C-terminal AF_0935 a4e53e3692b34f2d6c1017e242a20c19 326 SUPERFAMILY SSF51735 1 168 8.52E-28 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0935 a4e53e3692b34f2d6c1017e242a20c19 326 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 8 139 3.2E-12 T 31-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 AF_0935 a4e53e3692b34f2d6c1017e242a20c19 326 SUPERFAMILY SSF55347 147 306 9.15E-47 T 31-10-2018 AF_0935 a4e53e3692b34f2d6c1017e242a20c19 326 Pfam PF00742 Homoserine dehydrogenase 147 318 4.5E-58 T 31-10-2018 IPR001342 Homoserine dehydrogenase, catalytic GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AF_0935 a4e53e3692b34f2d6c1017e242a20c19 326 PIRSF PIRSF036497 1 325 1.2E-98 T 31-10-2018 IPR022697 Homoserine dehydrogenase lacking ACT domain GO:0004412 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AF_0935 a4e53e3692b34f2d6c1017e242a20c19 326 Gene3D G3DSA:3.30.360.10 158 302 6.2E-119 T 31-10-2018 AF_0935 a4e53e3692b34f2d6c1017e242a20c19 326 Gene3D G3DSA:3.40.50.720 4 319 6.2E-119 T 31-10-2018 AF_0935 a4e53e3692b34f2d6c1017e242a20c19 326 ProSitePatterns PS01042 Homoserine dehydrogenase signature. 193 215 - T 31-10-2018 IPR019811 Homoserine dehydrogenase, conserved site GO:0006520|GO:0055114 KEGG: 00260+1.1.1.3|KEGG: 00270+1.1.1.3|KEGG: 00300+1.1.1.3 AF_1497 c3748b5e412b549298d1a8d37c539f32 416 SUPERFAMILY SSF55205 3 411 4.25E-101 T 31-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 AF_1497 c3748b5e412b549298d1a8d37c539f32 416 Gene3D G3DSA:3.65.10.10 20 226 2.3E-118 T 31-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AF_1497 c3748b5e412b549298d1a8d37c539f32 416 Hamap MF_00210 3-phosphoshikimate 1-carboxyvinyltransferase [aroA]. 8 412 33.503 T 31-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AF_1497 c3748b5e412b549298d1a8d37c539f32 416 PIRSF PIRSF000505 1 415 1.6E-140 T 31-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AF_1497 c3748b5e412b549298d1a8d37c539f32 416 TIGRFAM TIGR01356 aroA: 3-phosphoshikimate 1-carboxyvinyltransferase 12 411 7.8E-123 T 31-10-2018 IPR006264 3-phosphoshikimate 1-carboxyvinyltransferase GO:0003866|GO:0009073 KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AF_1497 c3748b5e412b549298d1a8d37c539f32 416 ProSitePatterns PS00885 EPSP synthase signature 2. 325 343 - T 31-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AF_1497 c3748b5e412b549298d1a8d37c539f32 416 Gene3D G3DSA:3.65.10.10 12 403 2.3E-118 T 31-10-2018 IPR036968 Enolpyruvate transferase domain superfamily GO:0016765 AF_1497 c3748b5e412b549298d1a8d37c539f32 416 Pfam PF00275 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) 8 406 1.1E-94 T 31-10-2018 IPR001986 Enolpyruvate transferase domain GO:0016765 AF_1497 c3748b5e412b549298d1a8d37c539f32 416 ProSitePatterns PS00104 EPSP synthase signature 1. 82 96 - T 31-10-2018 IPR023193 3-phosphoshikimate 1-carboxyvinyltransferase, conserved site KEGG: 00400+2.5.1.19|MetaCyc: PWY-6163 AF_2338 0551cd691c870d07ae983071e89767fd 336 Gene3D G3DSA:3.40.50.300 69 247 1.7E-5 T 31-10-2018 AF_2338 0551cd691c870d07ae983071e89767fd 336 Pfam PF04465 Protein of unknown function (DUF499) 157 308 1.9E-12 T 31-10-2018 IPR007555 Protein of unknown function DUF499 AF_1492 7da8e5f4f1bf19d195efdaf9e4e15e7f 106 Pfam PF00428 60s Acidic ribosomal protein 16 105 7.6E-22 T 31-10-2018 AF_1492 7da8e5f4f1bf19d195efdaf9e4e15e7f 106 Gene3D G3DSA:1.10.10.1410 1 58 5.1E-31 T 31-10-2018 IPR038716 Ribosomal protein P1/P2, N-terminal domain Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1492 7da8e5f4f1bf19d195efdaf9e4e15e7f 106 Hamap MF_01478 50S ribosomal protein L12 [rpl12]. 1 106 14.701 T 31-10-2018 IPR027534 Ribosomal protein L12 family GO:0003735|GO:0005622|GO:0005840|GO:0006414 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1492 7da8e5f4f1bf19d195efdaf9e4e15e7f 106 TIGRFAM TIGR03685 ribo_P1_arch: 50S ribosomal protein P1 1 106 9.8E-44 T 31-10-2018 IPR022295 Ribosomal protein L12, archaea GO:0003735|GO:0005840|GO:0006414 AF_0543 fe091599631abc1da61a81cf42e48147 538 SUPERFAMILY SSF46548 105 209 8.2E-13 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_0543 fe091599631abc1da61a81cf42e48147 538 Pfam PF02754 Cysteine-rich domain 400 499 9.3E-7 T 31-10-2018 IPR004017 Cysteine-rich domain AF_0543 fe091599631abc1da61a81cf42e48147 538 Pfam PF13183 4Fe-4S dicluster domain 109 197 2.6E-10 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0543 fe091599631abc1da61a81cf42e48147 538 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 183 194 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0543 fe091599631abc1da61a81cf42e48147 538 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 112 123 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1115 06ae0ffd7e598825c53ef8ac87954e8c 186 Pfam PF04019 Protein of unknown function (DUF359) 49 171 4.4E-36 T 31-10-2018 IPR007164 Protein of unknown function DUF359 AF_1115 06ae0ffd7e598825c53ef8ac87954e8c 186 PIRSF PIRSF006533 1 175 5.2E-61 T 31-10-2018 IPR007164 Protein of unknown function DUF359 AF_1115 06ae0ffd7e598825c53ef8ac87954e8c 186 Hamap MF_00590 UPF0218 protein . 6 173 28.141 T 31-10-2018 IPR007164 Protein of unknown function DUF359 AF_0247 2b3bd35c7f9b89e111e6a7bae95840a5 455 Gene3D G3DSA:3.40.720.10 2 455 6.4E-33 T 31-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AF_0247 2b3bd35c7f9b89e111e6a7bae95840a5 455 SUPERFAMILY SSF53649 4 453 2.62E-50 T 31-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AF_0247 2b3bd35c7f9b89e111e6a7bae95840a5 455 Pfam PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase 5 414 4.1E-53 T 31-10-2018 IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase GO:0003824 AF_0795 039b1ad1392bf0634fa56f82878d4b22 289 SUPERFAMILY SSF52540 46 265 6.23E-25 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0795 039b1ad1392bf0634fa56f82878d4b22 289 TIGRFAM TIGR03878 thermo_KaiC_2: KaiC domain protein, AF_0795 family 17 274 1.2E-128 T 31-10-2018 IPR022373 KaiC domain-containing protein AF_0795 039b1ad1392bf0634fa56f82878d4b22 289 Pfam PF06745 KaiC 20 272 5.8E-72 T 31-10-2018 IPR014774 KaiC-like domain AF_0795 039b1ad1392bf0634fa56f82878d4b22 289 Gene3D G3DSA:3.40.50.300 14 271 2.8E-35 T 31-10-2018 AF_1222 a33b12eef49f676e1c09817e522aaccd 479 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 125 150 - T 31-10-2018 IPR018212 Sodium/solute symporter, conserved site AF_1222 a33b12eef49f676e1c09817e522aaccd 479 Pfam PF00474 Sodium:solute symporter family 4 434 1.8E-48 T 31-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AF_1222 a33b12eef49f676e1c09817e522aaccd 479 Gene3D G3DSA:1.20.1730.10 1 478 2.4E-61 T 31-10-2018 IPR038377 Sodium/glucose symporter superfamily AF_0591 bee5b09f9bb0d97b94bdc548c5db8eb7 135 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 14 132 10.499 T 31-10-2018 IPR022907 VapC family GO:0004540 AF_0591 bee5b09f9bb0d97b94bdc548c5db8eb7 135 SUPERFAMILY SSF88723 13 130 2.72E-30 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_0591 bee5b09f9bb0d97b94bdc548c5db8eb7 135 SMART SM00670 12 111 7.7E-13 T 31-10-2018 IPR002716 PIN domain AF_0591 bee5b09f9bb0d97b94bdc548c5db8eb7 135 Gene3D G3DSA:3.40.50.1010 10 135 1.5E-36 T 31-10-2018 AF_1500 49d0f8a55b794ca6a24f714255877409 114 SUPERFAMILY SSF103196 1 110 4.32E-22 T 31-10-2018 AF_1500 49d0f8a55b794ca6a24f714255877409 114 Gene3D G3DSA:3.30.450.30 1 114 1.7E-19 T 31-10-2018 AF_1500 49d0f8a55b794ca6a24f714255877409 114 SMART SM00960 2 90 1.3E-15 T 31-10-2018 IPR004942 Roadblock/LAMTOR2 domain AF_1500 49d0f8a55b794ca6a24f714255877409 114 Pfam PF03259 Roadblock/LC7 domain 2 90 3.6E-19 T 31-10-2018 IPR004942 Roadblock/LAMTOR2 domain AF_1704 bb52f1fa1e8412dd3f29b7864bb6819d 271 Hamap MF_00996 1,4-dihydroxy-6-naphtoate synthase [mqnD]. 2 262 43.191 T 31-10-2018 IPR030869 1,4-dihydroxy-6-naphtoate synthase GO:0009234|GO:0016829 AF_1704 bb52f1fa1e8412dd3f29b7864bb6819d 271 Gene3D G3DSA:3.40.190.10 6 257 1.0E-100 T 31-10-2018 AF_1704 bb52f1fa1e8412dd3f29b7864bb6819d 271 SUPERFAMILY SSF53850 3 261 1.58E-93 T 31-10-2018 AF_1704 bb52f1fa1e8412dd3f29b7864bb6819d 271 Gene3D G3DSA:3.40.190.10 79 170 1.0E-100 T 31-10-2018 AF_1704 bb52f1fa1e8412dd3f29b7864bb6819d 271 Pfam PF02621 Menaquinone biosynthesis 3 256 5.7E-87 T 31-10-2018 IPR003773 Menaquinone biosynthesis enzyme AF_1767 3c353c3bda1cb144ce9b9029c0ec5aa3 520 Gene3D G3DSA:3.10.105.10 434 520 1.1E-16 T 31-10-2018 AF_1767 3c353c3bda1cb144ce9b9029c0ec5aa3 520 Gene3D G3DSA:3.10.105.10 10 164 7.9E-33 T 31-10-2018 AF_1767 3c353c3bda1cb144ce9b9029c0ec5aa3 520 SUPERFAMILY SSF53850 196 518 6.15E-96 T 31-10-2018 AF_1767 3c353c3bda1cb144ce9b9029c0ec5aa3 520 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 241 519 4.8E-80 T 31-10-2018 IPR000914 Solute-binding protein family 5 domain AF_1767 3c353c3bda1cb144ce9b9029c0ec5aa3 520 Pfam PF00496 Bacterial extracellular solute-binding proteins, family 5 Middle 33 116 7.8E-13 T 31-10-2018 IPR000914 Solute-binding protein family 5 domain AF_1767 3c353c3bda1cb144ce9b9029c0ec5aa3 520 Gene3D G3DSA:3.40.190.10 189 433 2.5E-71 T 31-10-2018 AF_1767 3c353c3bda1cb144ce9b9029c0ec5aa3 520 SUPERFAMILY SSF53850 30 193 4.34E-36 T 31-10-2018 AF_1767 3c353c3bda1cb144ce9b9029c0ec5aa3 520 PIRSF PIRSF002741 4 196 4.0E-27 T 31-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 AF_1767 3c353c3bda1cb144ce9b9029c0ec5aa3 520 PIRSF PIRSF002741 191 520 1.3E-71 T 31-10-2018 IPR030678 Peptide/nickel binding protein, MppA-type GO:0043190|GO:0055085 AF_0215 7521fa5d1af14ba088546a923e539897 109 Pfam PF01849 NAC domain 6 63 5.1E-16 T 31-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain AF_0215 7521fa5d1af14ba088546a923e539897 109 Gene3D G3DSA:2.20.70.30 10 67 3.6E-19 T 31-10-2018 IPR038187 NAC A/B domain superfamily AF_0215 7521fa5d1af14ba088546a923e539897 109 SMART SM01407 6 64 1.7E-21 T 31-10-2018 IPR002715 Nascent polypeptide-associated complex NAC domain AF_0215 7521fa5d1af14ba088546a923e539897 109 Hamap MF_00814 Nascent polypeptide-associated complex protein [nac]. 7 108 21.427 T 31-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 AF_0215 7521fa5d1af14ba088546a923e539897 109 Gene3D G3DSA:1.10.8.10 69 108 1.4E-18 T 31-10-2018 AF_0215 7521fa5d1af14ba088546a923e539897 109 TIGRFAM TIGR00264 TIGR00264: alpha-NAC homolog 1 109 1.0E-51 T 31-10-2018 IPR005231 Nascent polypeptide-associated complex (NAC), archaeal GO:0003723 AF_0215 7521fa5d1af14ba088546a923e539897 109 SUPERFAMILY SSF46934 66 108 1.13E-7 T 31-10-2018 IPR009060 UBA-like superfamily GO:0005515 AF_1339 f5fad4cabea74d9fcf84e2ac0fc812aa 174 TIGRFAM TIGR00279 uL16_euk_arch: ribosomal protein uL16 1 171 1.9E-92 T 31-10-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1339 f5fad4cabea74d9fcf84e2ac0fc812aa 174 PIRSF PIRSF005590 1 174 3.3E-75 T 31-10-2018 IPR001197 Ribosomal protein L10e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1339 f5fad4cabea74d9fcf84e2ac0fc812aa 174 SUPERFAMILY SSF54686 4 168 9.81E-62 T 31-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 AF_1339 f5fad4cabea74d9fcf84e2ac0fc812aa 174 ProSitePatterns PS01257 Ribosomal protein L10e signature. 104 125 - T 31-10-2018 IPR018255 Ribosomal protein L10e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1339 f5fad4cabea74d9fcf84e2ac0fc812aa 174 Hamap MF_00448 50S ribosomal protein L10e [rpl10e]. 1 171 41.585 T 31-10-2018 IPR022981 Ribosomal protein L10e, archaea AF_1339 f5fad4cabea74d9fcf84e2ac0fc812aa 174 Pfam PF00252 Ribosomal protein L16p/L10e 14 162 7.3E-37 T 31-10-2018 IPR016180 Ribosomal protein L10e/L16 GO:0003735|GO:0005840|GO:0006412 AF_1339 f5fad4cabea74d9fcf84e2ac0fc812aa 174 Gene3D G3DSA:3.90.1170.10 1 173 1.3E-70 T 31-10-2018 IPR036920 Ribosomal protein L10e/L16 superfamily GO:0003735|GO:0005840|GO:0006412 AF_2029 3f4e04a899848f9e4e1671c53b9ba1d3 473 Gene3D G3DSA:3.90.1640.10 157 336 1.0E-32 T 31-10-2018 AF_2029 3f4e04a899848f9e4e1671c53b9ba1d3 473 SUPERFAMILY SSF64182 158 439 1.31E-62 T 31-10-2018 IPR038763 DHH phosphoesterase superfamily AF_2029 3f4e04a899848f9e4e1671c53b9ba1d3 473 Pfam PF02272 DHHA1 domain 351 455 1.2E-16 T 31-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 AF_2029 3f4e04a899848f9e4e1671c53b9ba1d3 473 SUPERFAMILY SSF51735 8 130 3.13E-19 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_2029 3f4e04a899848f9e4e1671c53b9ba1d3 473 Gene3D G3DSA:3.40.50.720 2 141 7.7E-31 T 31-10-2018 AF_2029 3f4e04a899848f9e4e1671c53b9ba1d3 473 Pfam PF01368 DHH family 161 300 1.3E-11 T 31-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AF_2029 3f4e04a899848f9e4e1671c53b9ba1d3 473 Pfam PF02254 TrkA-N domain 9 121 7.5E-22 T 31-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AF_2256 79470b9b6a2e60da592f115cf6719fef 249 Gene3D G3DSA:3.30.1330.100 6 228 9.2E-100 T 31-10-2018 AF_2256 79470b9b6a2e60da592f115cf6719fef 249 Pfam PF01996 F420-0:Gamma-glutamyl ligase 11 220 4.0E-63 T 31-10-2018 IPR002847 Coenzyme F420:L-glutamate ligase-like domain KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 AF_2256 79470b9b6a2e60da592f115cf6719fef 249 TIGRFAM TIGR01916 F420_cofE: coenzyme F420-0:L-glutamate ligase 3 242 2.8E-111 T 31-10-2018 IPR008225 Coenzyme F420:L-glutamate ligase GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 AF_2256 79470b9b6a2e60da592f115cf6719fef 249 Gene3D G3DSA:3.90.1660.10 50 242 9.2E-100 T 31-10-2018 AF_2256 79470b9b6a2e60da592f115cf6719fef 249 SUPERFAMILY SSF144010 4 247 3.27E-83 T 31-10-2018 AF_2256 79470b9b6a2e60da592f115cf6719fef 249 Hamap MF_01258 Coenzyme F420:L-glutamate ligase [cofE]. 3 242 45.136 T 31-10-2018 IPR023659 Coenzyme F420:L-glutamate ligase, archaeal GO:0043773|GO:0046872|GO:0051188 KEGG: 00680+6.3.2.31+6.3.2.34|MetaCyc: PWY-5199 AF_1209 be39cd6735ef96f44a2fd098a3119b15 213 Gene3D G3DSA:3.40.50.720 1 213 1.9E-52 T 31-10-2018 AF_1209 be39cd6735ef96f44a2fd098a3119b15 213 TIGRFAM TIGR01915 npdG: NADPH-dependent F420 reductase 1 212 1.6E-68 T 31-10-2018 IPR010185 NADPH-dependent F420 reductase GO:0006740|GO:0016651|GO:0050661|GO:0055114|GO:0070967 AF_1209 be39cd6735ef96f44a2fd098a3119b15 213 SUPERFAMILY SSF51735 1 204 1.56E-41 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1209 be39cd6735ef96f44a2fd098a3119b15 213 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 99 1.8E-21 T 31-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal AF_2368 7bda1232f0e66fe66df111d1f2e63aef 562 Gene3D G3DSA:3.40.50.12780 39 454 3.1E-118 T 31-10-2018 AF_2368 7bda1232f0e66fe66df111d1f2e63aef 562 ProSitePatterns PS00455 Putative AMP-binding domain signature. 215 226 - T 31-10-2018 IPR020845 AMP-binding, conserved site AF_2368 7bda1232f0e66fe66df111d1f2e63aef 562 Gene3D G3DSA:3.30.300.310 457 561 1.9E-35 T 31-10-2018 AF_2368 7bda1232f0e66fe66df111d1f2e63aef 562 SUPERFAMILY SSF56801 31 557 3.4E-158 T 31-10-2018 AF_2368 7bda1232f0e66fe66df111d1f2e63aef 562 Pfam PF00501 AMP-binding enzyme 48 460 1.8E-106 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_2368 7bda1232f0e66fe66df111d1f2e63aef 562 Pfam PF13193 AMP-binding enzyme C-terminal domain 470 547 4.7E-22 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AF_0226 c12317ed7134b22e3875078390b27903 172 Pfam PF00881 Nitroreductase family 65 150 3.9E-19 T 31-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 AF_0226 c12317ed7134b22e3875078390b27903 172 Gene3D G3DSA:3.40.109.10 3 172 1.2E-60 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AF_0226 c12317ed7134b22e3875078390b27903 172 SUPERFAMILY SSF55469 1 172 1.31E-58 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AF_0514 c219742e3f885f7f9e3a06dda52f4130 187 Pfam PF01738 Dienelactone hydrolase family 70 160 9.1E-5 T 31-10-2018 IPR002925 Dienelactone hydrolase GO:0016787 AF_0514 c219742e3f885f7f9e3a06dda52f4130 187 Gene3D G3DSA:3.40.50.1820 9 186 3.6E-26 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_0514 c219742e3f885f7f9e3a06dda52f4130 187 SUPERFAMILY SSF53474 20 184 1.59E-23 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_1240 7773338d59e3c3493686f6d65fc7a627 435 TIGRFAM TIGR01415 trpB_rel: pyridoxal-phosphate dependent TrpB-like enzyme 16 430 5.7E-212 T 31-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AF_1240 7773338d59e3c3493686f6d65fc7a627 435 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 24 428 41.902 T 31-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AF_1240 7773338d59e3c3493686f6d65fc7a627 435 PIRSF PIRSF500824 5 435 8.2E-217 T 31-10-2018 IPR006316 Tryptophan synthase, beta chain-like GO:0000162|GO:0004834|GO:0030170 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AF_1240 7773338d59e3c3493686f6d65fc7a627 435 PIRSF PIRSF001413 12 434 3.2E-130 T 31-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AF_1240 7773338d59e3c3493686f6d65fc7a627 435 Gene3D G3DSA:3.40.50.1100 17 241 1.8E-176 T 31-10-2018 AF_1240 7773338d59e3c3493686f6d65fc7a627 435 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 80 415 9.1E-41 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AF_1240 7773338d59e3c3493686f6d65fc7a627 435 SUPERFAMILY SSF53686 30 428 4.06E-113 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AF_1240 7773338d59e3c3493686f6d65fc7a627 435 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 108 122 - T 31-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AF_1240 7773338d59e3c3493686f6d65fc7a627 435 Gene3D G3DSA:3.40.50.1100 16 421 1.8E-176 T 31-10-2018 AF_1930 58d05c0e0fdfa3cc21272a6075fd3d23 563 Gene3D G3DSA:3.20.20.140 433 455 5.7E-10 T 31-10-2018 AF_1930 58d05c0e0fdfa3cc21272a6075fd3d23 563 Gene3D G3DSA:2.30.40.10 4 84 5.1E-13 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AF_1930 58d05c0e0fdfa3cc21272a6075fd3d23 563 TIGRFAM TIGR03121 one_C_dehyd_A: formylmethanofuran dehydrogenase subunit A 6 558 1.2E-252 T 31-10-2018 IPR012027 Formylmethanofuran dehydrogenase, subunit A AF_1930 58d05c0e0fdfa3cc21272a6075fd3d23 563 SUPERFAMILY SSF51338 386 518 3.65E-32 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AF_1930 58d05c0e0fdfa3cc21272a6075fd3d23 563 SUPERFAMILY SSF51338 5 71 3.57E-14 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AF_1930 58d05c0e0fdfa3cc21272a6075fd3d23 563 Pfam PF07969 Amidohydrolase family 46 502 1.2E-94 T 31-10-2018 IPR013108 Amidohydrolase 3 AF_1930 58d05c0e0fdfa3cc21272a6075fd3d23 563 SUPERFAMILY SSF51556 58 455 1.61E-19 T 31-10-2018 IPR032466 Metal-dependent hydrolase AF_1930 58d05c0e0fdfa3cc21272a6075fd3d23 563 Gene3D G3DSA:2.30.40.10 456 510 5.7E-10 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AF_1930 58d05c0e0fdfa3cc21272a6075fd3d23 563 PIRSF PIRSF006453 3 563 3.7E-241 T 31-10-2018 IPR012027 Formylmethanofuran dehydrogenase, subunit A AF_0931 ea6002e329501a326ced352482d0e53f 654 Pfam PF03454 MoeA C-terminal region (domain IV) 338 409 2.1E-18 T 31-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AF_0931 ea6002e329501a326ced352482d0e53f 654 Gene3D G3DSA:2.40.340.10 335 411 5.7E-20 T 31-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AF_0931 ea6002e329501a326ced352482d0e53f 654 SMART SM00852 187 325 3.0E-40 T 31-10-2018 IPR001453 MoaB/Mog domain AF_0931 ea6002e329501a326ced352482d0e53f 654 SUPERFAMILY SSF63867 336 411 7.59E-16 T 31-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AF_0931 ea6002e329501a326ced352482d0e53f 654 Gene3D G3DSA:3.90.105.10 30 181 6.5E-110 T 31-10-2018 AF_0931 ea6002e329501a326ced352482d0e53f 654 SUPERFAMILY SSF53218 184 329 2.09E-39 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily AF_0931 ea6002e329501a326ced352482d0e53f 654 Gene3D G3DSA:2.170.190.11 52 148 6.5E-110 T 31-10-2018 AF_0931 ea6002e329501a326ced352482d0e53f 654 Pfam PF12727 PBP superfamily domain 434 626 1.3E-60 T 31-10-2018 IPR024370 PBP domain AF_0931 ea6002e329501a326ced352482d0e53f 654 Gene3D G3DSA:3.40.980.10 182 324 6.5E-110 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily AF_0931 ea6002e329501a326ced352482d0e53f 654 SUPERFAMILY SSF63882 8 181 1.44E-58 T 31-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AF_0931 ea6002e329501a326ced352482d0e53f 654 Gene3D G3DSA:3.40.190.10 498 606 8.8E-10 T 31-10-2018 AF_0931 ea6002e329501a326ced352482d0e53f 654 SUPERFAMILY SSF53850 435 642 1.65E-21 T 31-10-2018 AF_0931 ea6002e329501a326ced352482d0e53f 654 Pfam PF00994 Probable molybdopterin binding domain 187 324 8.0E-26 T 31-10-2018 IPR001453 MoaB/Mog domain AF_0931 ea6002e329501a326ced352482d0e53f 654 Pfam PF03453 MoeA N-terminal region (domain I and II) 10 174 5.2E-47 T 31-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AF_0931 ea6002e329501a326ced352482d0e53f 654 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 260 294 - T 31-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 AF_0931 ea6002e329501a326ced352482d0e53f 654 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 184 321 1.4E-35 T 31-10-2018 IPR001453 MoaB/Mog domain AF_0508 85e5d0ea39d1922bf4d0712938e8dd67 336 Gene3D G3DSA:3.20.20.70 8 319 1.6E-147 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0508 85e5d0ea39d1922bf4d0712938e8dd67 336 Pfam PF05690 Thiazole biosynthesis protein ThiG 241 298 9.3E-7 T 31-10-2018 IPR033983 Thiazole synthase ThiG KEGG: 00730+2.8.1.10|MetaCyc: PWY-6891|MetaCyc: PWY-6892 AF_0508 85e5d0ea39d1922bf4d0712938e8dd67 336 ProSitePatterns PS01235 PdxS/SNZ family signature. 247 265 - T 31-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AF_0508 85e5d0ea39d1922bf4d0712938e8dd67 336 SUPERFAMILY SSF51366 24 310 4.0E-63 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AF_0508 85e5d0ea39d1922bf4d0712938e8dd67 336 Hamap MF_01824 Pyridoxal 5'-phosphate synthase subunit PdxS [pdxS]. 10 336 53.132 T 31-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AF_0508 85e5d0ea39d1922bf4d0712938e8dd67 336 PIRSF PIRSF029271 1 336 6.8E-154 T 31-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AF_0508 85e5d0ea39d1922bf4d0712938e8dd67 336 Pfam PF01680 SOR/SNZ family 14 215 5.9E-95 T 31-10-2018 IPR033755 PdxS/SNZ N-terminal domain KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AF_0508 85e5d0ea39d1922bf4d0712938e8dd67 336 TIGRFAM TIGR00343 TIGR00343: pyridoxal 5'-phosphate synthase, synthase subunit Pdx1 15 335 9.8E-159 T 31-10-2018 IPR001852 Pyridoxal 5'-phosphate synthase subunit PdxS/SNZ GO:0042819|GO:0042823 KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AF_1975 d3ee8d914a12f28f4b61acb7e308b71f 437 SUPERFAMILY SSF69742 1 146 6.93E-37 T 31-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AF_1975 d3ee8d914a12f28f4b61acb7e308b71f 437 PIRSF PIRSF000445 1 422 3.4E-131 T 31-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AF_1975 d3ee8d914a12f28f4b61acb7e308b71f 437 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 159 293 2.7E-45 T 31-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase AF_1975 d3ee8d914a12f28f4b61acb7e308b71f 437 ProSitePatterns PS00747 Glutamyl-tRNA reductase signature. 87 110 - T 31-10-2018 IPR018214 Glutamyl-tRNA reductase, conserved site GO:0008883|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AF_1975 d3ee8d914a12f28f4b61acb7e308b71f 437 Gene3D G3DSA:3.40.50.720 149 300 1.3E-48 T 31-10-2018 AF_1975 d3ee8d914a12f28f4b61acb7e308b71f 437 SUPERFAMILY SSF51735 148 301 1.11E-37 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1975 d3ee8d914a12f28f4b61acb7e308b71f 437 Gene3D G3DSA:3.30.460.30 1 148 1.0E-37 T 31-10-2018 IPR036343 Glutamyl-tRNA reductase, N-terminal domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AF_1975 d3ee8d914a12f28f4b61acb7e308b71f 437 SUPERFAMILY SSF69075 304 409 6.28E-21 T 31-10-2018 IPR036453 Glutamyl tRNA-reductase dimerization domain superfamily GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AF_1975 d3ee8d914a12f28f4b61acb7e308b71f 437 Pfam PF00745 Glutamyl-tRNAGlu reductase, dimerisation domain 307 407 6.4E-16 T 31-10-2018 IPR015896 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, dimerisation domain GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AF_1975 d3ee8d914a12f28f4b61acb7e308b71f 437 TIGRFAM TIGR01035 hemA: glutamyl-tRNA reductase 3 408 1.6E-159 T 31-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AF_1975 d3ee8d914a12f28f4b61acb7e308b71f 437 Pfam PF05201 Glutamyl-tRNAGlu reductase, N-terminal domain 6 144 7.8E-36 T 31-10-2018 IPR015895 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase, N-terminal GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AF_1975 d3ee8d914a12f28f4b61acb7e308b71f 437 Hamap MF_00087 Glutamyl-tRNA reductase [hemA]. 2 406 27.318 T 31-10-2018 IPR000343 Tetrapyrrole biosynthesis, glutamyl-tRNA reductase GO:0008883|GO:0033014|GO:0050661|GO:0055114 KEGG: 00860+1.2.1.70|MetaCyc: PWY-5188 AF_0423 58b7541d89e4faeb6ea3618fbc45e259 418 SUPERFAMILY SSF55124 3 167 1.94E-73 T 31-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AF_0423 58b7541d89e4faeb6ea3618fbc45e259 418 SUPERFAMILY SSF54862 229 303 1.26E-19 T 31-10-2018 AF_0423 58b7541d89e4faeb6ea3618fbc45e259 418 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 91 155 1.4E-7 T 31-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AF_0423 58b7541d89e4faeb6ea3618fbc45e259 418 SUPERFAMILY SSF56014 167 403 3.6E-60 T 31-10-2018 AF_0423 58b7541d89e4faeb6ea3618fbc45e259 418 Gene3D G3DSA:3.30.70.2500 63 164 1.3E-51 T 31-10-2018 AF_0423 58b7541d89e4faeb6ea3618fbc45e259 418 Gene3D G3DSA:3.30.413.10 165 398 3.1E-115 T 31-10-2018 AF_0423 58b7541d89e4faeb6ea3618fbc45e259 418 TIGRFAM TIGR02064 dsrA: sulfite reductase, dissimilatory-type alpha subunit 7 408 2.0E-212 T 31-10-2018 IPR011806 Sulphite reductase, dissimilatory-type alpha subunit GO:0018551|GO:0020037|GO:0051539|GO:0055114 AF_0423 58b7541d89e4faeb6ea3618fbc45e259 418 Gene3D G3DSA:3.30.70.20 239 306 3.1E-115 T 31-10-2018 AF_0423 58b7541d89e4faeb6ea3618fbc45e259 418 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 166 381 3.1E-45 T 31-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AF_1883 5a6b6ed0110df906780a695594efcc79 251 PRINTS PR00164 ABC-2 type transport system membrane protein signature 22 43 2.2E-11 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AF_1883 5a6b6ed0110df906780a695594efcc79 251 PRINTS PR00164 ABC-2 type transport system membrane protein signature 192 211 2.2E-11 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AF_1883 5a6b6ed0110df906780a695594efcc79 251 PRINTS PR00164 ABC-2 type transport system membrane protein signature 135 159 2.2E-11 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AF_1883 5a6b6ed0110df906780a695594efcc79 251 PRINTS PR00164 ABC-2 type transport system membrane protein signature 172 191 2.2E-11 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AF_1883 5a6b6ed0110df906780a695594efcc79 251 TIGRFAM TIGR01247 drrB: daunorubicin resistance ABC transporter membrane protein 10 245 1.9E-119 T 31-10-2018 IPR005942 Daunorubicin resistance ABC transporter membrane protein AF_1883 5a6b6ed0110df906780a695594efcc79 251 PIRSF PIRSF006648 1 250 4.6E-65 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AF_1883 5a6b6ed0110df906780a695594efcc79 251 Pfam PF01061 ABC-2 type transporter 3 214 1.8E-40 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AF_0972 3e95be567991a40e43c8d9db77b7ce3e 205 SUPERFAMILY SSF53098 5 182 7.21E-39 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily AF_0972 3e95be567991a40e43c8d9db77b7ce3e 205 SMART SM00479 9 180 8.6E-45 T 31-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AF_0972 3e95be567991a40e43c8d9db77b7ce3e 205 TIGRFAM TIGR00573 dnaq: exonuclease, DNA polymerase III, epsilon subunit family 3 203 5.6E-75 T 31-10-2018 IPR006054 DNA polymerase III epsilon subunit, exonuclease domain GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AF_0972 3e95be567991a40e43c8d9db77b7ce3e 205 Pfam PF00929 Exonuclease 12 171 6.5E-35 T 31-10-2018 IPR013520 Exonuclease, RNase T/DNA polymerase III AF_0972 3e95be567991a40e43c8d9db77b7ce3e 205 Gene3D G3DSA:3.30.420.10 4 178 3.7E-36 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AF_0574 e6b5dc63f0068a40f9e54c3a246c11c8 88 SMART SM00888 3 88 3.0E-34 T 31-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 AF_0574 e6b5dc63f0068a40f9e54c3a246c11c8 88 PIRSF PIRSF006521 1 88 5.3E-31 T 31-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 AF_0574 e6b5dc63f0068a40f9e54c3a246c11c8 88 Hamap MF_00043 Elongation factor 1-beta [ef1b]. 1 88 34.669 T 31-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 AF_0574 e6b5dc63f0068a40f9e54c3a246c11c8 88 SUPERFAMILY SSF54984 1 88 1.16E-24 T 31-10-2018 IPR036219 Translation elongation factor eEF-1beta-like superfamily Reactome: R-HSA-156842 AF_0574 e6b5dc63f0068a40f9e54c3a246c11c8 88 Pfam PF00736 EF-1 guanine nucleotide exchange domain 6 86 6.8E-23 T 31-10-2018 IPR014038 Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain GO:0003746|GO:0006414 Reactome: R-HSA-156842 AF_0574 e6b5dc63f0068a40f9e54c3a246c11c8 88 TIGRFAM TIGR00489 aEF-1_beta: translation elongation factor aEF-1 beta 1 88 9.2E-44 T 31-10-2018 IPR004542 Translation elongation factor EF1B, beta chain, archaeal GO:0003746|GO:0006414 AF_0574 e6b5dc63f0068a40f9e54c3a246c11c8 88 Gene3D G3DSA:3.30.70.60 1 88 1.0E-26 T 31-10-2018 IPR014717 Translation elongation factor EF1B/ribosomal protein S6 AF_2178 865ae39cb37341bfeee732e20d2990f6 392 SMART SM00981 87 183 4.4E-21 T 31-10-2018 IPR004114 THUMP domain GO:0003723 AF_2178 865ae39cb37341bfeee732e20d2990f6 392 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 314 320 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AF_2178 865ae39cb37341bfeee732e20d2990f6 392 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 332 356 1.2E-6 T 31-10-2018 AF_2178 865ae39cb37341bfeee732e20d2990f6 392 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 223 237 1.2E-6 T 31-10-2018 AF_2178 865ae39cb37341bfeee732e20d2990f6 392 PRINTS PR00507 N12 class N6 adenine-specific DNA methyltransferase signature 311 323 1.2E-6 T 31-10-2018 AF_2178 865ae39cb37341bfeee732e20d2990f6 392 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 225 236 - T 31-10-2018 IPR000241 Putative RNA methylase domain AF_2178 865ae39cb37341bfeee732e20d2990f6 392 SUPERFAMILY SSF53335 177 353 6.98E-32 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_2178 865ae39cb37341bfeee732e20d2990f6 392 Pfam PF01170 Putative RNA methylase family UPF0020 192 385 7.7E-69 T 31-10-2018 IPR000241 Putative RNA methylase domain AF_2178 865ae39cb37341bfeee732e20d2990f6 392 Gene3D G3DSA:3.40.50.150 191 392 1.6E-43 T 31-10-2018 AF_2178 865ae39cb37341bfeee732e20d2990f6 392 SUPERFAMILY SSF143437 61 183 2.27E-16 T 31-10-2018 AF_2178 865ae39cb37341bfeee732e20d2990f6 392 Pfam PF02926 THUMP domain 48 183 7.5E-28 T 31-10-2018 IPR004114 THUMP domain GO:0003723 AF_2178 865ae39cb37341bfeee732e20d2990f6 392 Gene3D G3DSA:3.30.2130.30 31 190 3.1E-39 T 31-10-2018 AF_1192 e2e6d89e6a971ba046ddd9eb1fd8a930 664 Gene3D G3DSA:3.40.50.261 346 504 4.5E-46 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1192 e2e6d89e6a971ba046ddd9eb1fd8a930 664 Gene3D G3DSA:3.40.50.261 505 664 4.0E-36 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1192 e2e6d89e6a971ba046ddd9eb1fd8a930 664 Gene3D G3DSA:3.30.470.20 3 203 1.2E-72 T 31-10-2018 AF_1192 e2e6d89e6a971ba046ddd9eb1fd8a930 664 SUPERFAMILY SSF52210 507 658 9.81E-28 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1192 e2e6d89e6a971ba046ddd9eb1fd8a930 664 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 368 501 1.0E-43 T 31-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain AF_1192 e2e6d89e6a971ba046ddd9eb1fd8a930 664 SUPERFAMILY SSF56059 1 208 7.6E-43 T 31-10-2018 AF_1192 e2e6d89e6a971ba046ddd9eb1fd8a930 664 Gene3D G3DSA:3.30.1490.20 21 91 1.2E-72 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AF_1192 e2e6d89e6a971ba046ddd9eb1fd8a930 664 SUPERFAMILY SSF51735 213 353 5.44E-41 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1192 e2e6d89e6a971ba046ddd9eb1fd8a930 664 Pfam PF13549 ATP-grasp domain 2 205 1.1E-63 T 31-10-2018 AF_1192 e2e6d89e6a971ba046ddd9eb1fd8a930 664 SMART SM00881 221 316 4.0E-39 T 31-10-2018 IPR003781 CoA-binding GO:0048037 AF_1192 e2e6d89e6a971ba046ddd9eb1fd8a930 664 Gene3D G3DSA:3.40.50.720 215 345 1.9E-47 T 31-10-2018 AF_1192 e2e6d89e6a971ba046ddd9eb1fd8a930 664 Pfam PF13380 CoA binding domain 225 349 1.4E-26 T 31-10-2018 IPR003781 CoA-binding GO:0048037 AF_1192 e2e6d89e6a971ba046ddd9eb1fd8a930 664 SUPERFAMILY SSF52210 347 502 1.13E-32 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_0747 92342f55daf167dfd50f8b82d24367c7 280 Pfam PF01678 Diaminopimelate epimerase 5 127 2.0E-43 T 31-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AF_0747 92342f55daf167dfd50f8b82d24367c7 280 Pfam PF01678 Diaminopimelate epimerase 154 266 5.1E-24 T 31-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AF_0747 92342f55daf167dfd50f8b82d24367c7 280 ProSitePatterns PS01326 Diaminopimelate epimerase signature. 67 81 - T 31-10-2018 IPR018510 Diaminopimelate epimerase, active site GO:0005737|GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AF_0747 92342f55daf167dfd50f8b82d24367c7 280 Gene3D G3DSA:3.10.310.10 123 263 1.4E-88 T 31-10-2018 AF_0747 92342f55daf167dfd50f8b82d24367c7 280 Hamap MF_00197 Diaminopimelate epimerase [dapF]. 3 273 37.534 T 31-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AF_0747 92342f55daf167dfd50f8b82d24367c7 280 TIGRFAM TIGR00652 DapF: diaminopimelate epimerase 3 271 2.1E-99 T 31-10-2018 IPR001653 Diaminopimelate epimerase, DapF GO:0008837|GO:0009089 KEGG: 00300+5.1.1.7|MetaCyc: PWY-2941|MetaCyc: PWY-5097 AF_0747 92342f55daf167dfd50f8b82d24367c7 280 SUPERFAMILY SSF54506 141 271 2.51E-36 T 31-10-2018 AF_0747 92342f55daf167dfd50f8b82d24367c7 280 Gene3D G3DSA:3.10.310.10 5 269 1.4E-88 T 31-10-2018 AF_0747 92342f55daf167dfd50f8b82d24367c7 280 SUPERFAMILY SSF54506 3 133 3.31E-42 T 31-10-2018 AF_0170 9f50af779748019fb2fad69c404165a4 434 Pfam PF01814 Hemerythrin HHE cation binding domain 90 225 1.0E-20 T 31-10-2018 IPR012312 Haemerythrin-like Reactome: R-HSA-390471|Reactome: R-HSA-8951664|Reactome: R-HSA-917937|Reactome: R-HSA-983168 AF_0170 9f50af779748019fb2fad69c404165a4 434 Pfam PF13596 PAS domain 316 419 1.5E-25 T 31-10-2018 AF_0170 9f50af779748019fb2fad69c404165a4 434 SUPERFAMILY SSF55785 351 425 8.37E-7 T 31-10-2018 IPR035965 PAS domain superfamily AF_0170 9f50af779748019fb2fad69c404165a4 434 Gene3D G3DSA:1.20.120.520 83 294 2.5E-46 T 31-10-2018 AF_0170 9f50af779748019fb2fad69c404165a4 434 Gene3D G3DSA:3.30.450.20 297 430 3.0E-45 T 31-10-2018 AF_0170 9f50af779748019fb2fad69c404165a4 434 Pfam PF04282 Family of unknown function (DUF438) 13 78 2.6E-25 T 31-10-2018 IPR007380 Domain of unknown function DUF438 AF_0442 523b1283ac3617086845f9443a40210d 239 Gene3D G3DSA:3.40.50.620 1 216 1.0E-68 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_0442 523b1283ac3617086845f9443a40210d 239 TIGRFAM TIGR00364 TIGR00364: queuosine biosynthesis protein QueC 3 201 2.8E-78 T 31-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AF_0442 523b1283ac3617086845f9443a40210d 239 Pfam PF06508 Queuosine biosynthesis protein QueC 2 207 7.7E-71 T 31-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AF_0442 523b1283ac3617086845f9443a40210d 239 Hamap MF_01633 7-cyano-7-deazaguanine synthase [queC]. 1 214 50.246 T 31-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AF_0442 523b1283ac3617086845f9443a40210d 239 PIRSF PIRSF006293 1 221 1.7E-85 T 31-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AF_0442 523b1283ac3617086845f9443a40210d 239 SUPERFAMILY SSF52402 1 215 2.12E-59 T 31-10-2018 AF_1444 2176bfe3148eda296d5742ba52997684 410 SUPERFAMILY SSF53300 244 403 7.57E-18 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AF_1444 2176bfe3148eda296d5742ba52997684 410 Pfam PF13519 von Willebrand factor type A domain 244 336 1.5E-6 T 31-10-2018 IPR002035 von Willebrand factor, type A AF_1444 2176bfe3148eda296d5742ba52997684 410 Gene3D G3DSA:3.40.50.410 241 408 8.7E-17 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AF_1444 2176bfe3148eda296d5742ba52997684 410 SMART SM00327 240 403 1.4E-5 T 31-10-2018 IPR002035 von Willebrand factor, type A AF_1889 95d8c4c398592ee07d49063e6cabd262 380 Pfam PF04998 RNA polymerase Rpb1, domain 5 52 324 5.4E-59 T 31-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1889 95d8c4c398592ee07d49063e6cabd262 380 SUPERFAMILY SSF64484 26 376 3.89E-104 T 31-10-2018 AF_1889 95d8c4c398592ee07d49063e6cabd262 380 TIGRFAM TIGR02389 RNA_pol_rpoA2: DNA-directed RNA polymerase, subunit A'' 15 374 4.5E-156 T 31-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1889 95d8c4c398592ee07d49063e6cabd262 380 Gene3D G3DSA:1.10.150.390 325 370 2.7E-23 T 31-10-2018 AF_1889 95d8c4c398592ee07d49063e6cabd262 380 Hamap MF_00411 DNA-directed RNA polymerase subunit A'' [rpoA2]. 2 377 40.926 T 31-10-2018 IPR012757 DNA-directed RNA polymerase subunit A'' GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_0976 741128696eaf80fc00a3aec8dace7ce9 551 Gene3D G3DSA:3.30.300.30 447 551 2.5E-26 T 31-10-2018 AF_0976 741128696eaf80fc00a3aec8dace7ce9 551 Gene3D G3DSA:3.40.50.12780 28 444 7.1E-102 T 31-10-2018 AF_0976 741128696eaf80fc00a3aec8dace7ce9 551 Pfam PF13193 AMP-binding enzyme C-terminal domain 460 541 1.3E-19 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AF_0976 741128696eaf80fc00a3aec8dace7ce9 551 Pfam PF00501 AMP-binding enzyme 46 451 2.7E-94 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_0976 741128696eaf80fc00a3aec8dace7ce9 551 SUPERFAMILY SSF56801 29 549 2.75E-135 T 31-10-2018 AF_0976 741128696eaf80fc00a3aec8dace7ce9 551 ProSitePatterns PS00455 Putative AMP-binding domain signature. 196 207 - T 31-10-2018 IPR020845 AMP-binding, conserved site AF_0580 72653590310dec62ff8eadedf3205cc2 257 TIGRFAM TIGR00633 xth: exodeoxyribonuclease III (xth) 2 255 1.6E-88 T 31-10-2018 IPR004808 AP endonuclease 1 GO:0004518|GO:0006281 AF_0580 72653590310dec62ff8eadedf3205cc2 257 Gene3D G3DSA:3.60.10.10 1 257 2.7E-80 T 31-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AF_0580 72653590310dec62ff8eadedf3205cc2 257 Pfam PF03372 Endonuclease/Exonuclease/phosphatase family 5 248 8.5E-17 T 31-10-2018 IPR005135 Endonuclease/exonuclease/phosphatase AF_0580 72653590310dec62ff8eadedf3205cc2 257 ProSitePatterns PS00726 AP endonucleases family 1 signature 1. 28 37 - T 31-10-2018 IPR020847 AP endonuclease 1, binding site GO:0003677|GO:0004519|GO:0005622|GO:0006281 AF_0580 72653590310dec62ff8eadedf3205cc2 257 SUPERFAMILY SSF56219 2 256 6.94E-72 T 31-10-2018 IPR036691 Endonuclease/exonuclease/phosphatase superfamily AF_0580 72653590310dec62ff8eadedf3205cc2 257 TIGRFAM TIGR00195 exoDNase_III: exodeoxyribonuclease III 2 255 4.5E-108 T 31-10-2018 AF_0717 c3b314f2e443541e1983cde5fc1e33d7 214 Gene3D G3DSA:3.40.50.720 2 126 1.2E-26 T 31-10-2018 AF_0717 c3b314f2e443541e1983cde5fc1e33d7 214 Pfam PF02254 TrkA-N domain 3 113 6.5E-24 T 31-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AF_0717 c3b314f2e443541e1983cde5fc1e33d7 214 Gene3D G3DSA:3.30.70.1450 139 209 1.5E-7 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AF_0717 c3b314f2e443541e1983cde5fc1e33d7 214 Pfam PF02080 TrkA-C domain 144 207 3.8E-8 T 31-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AF_0717 c3b314f2e443541e1983cde5fc1e33d7 214 SUPERFAMILY SSF51735 1 138 2.35E-26 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0717 c3b314f2e443541e1983cde5fc1e33d7 214 SUPERFAMILY SSF116726 133 207 1.83E-7 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AF_0286 10281cdb88f8082d4d6010d681ba78af 247 SMART SM00893 23 210 1.4E-44 T 31-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AF_0286 10281cdb88f8082d4d6010d681ba78af 247 ProSitePatterns PS01065 Electron transfer flavoprotein beta-subunit signature. 153 174 - T 31-10-2018 IPR000049 Electron transfer flavoprotein, beta-subunit, conserved site GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 AF_0286 10281cdb88f8082d4d6010d681ba78af 247 Pfam PF01012 Electron transfer flavoprotein domain 30 204 3.0E-45 T 31-10-2018 IPR014730 Electron transfer flavoprotein, alpha/beta-subunit, N-terminal Reactome: R-HSA-611105 AF_0286 10281cdb88f8082d4d6010d681ba78af 247 PIRSF PIRSF000090 1 247 2.9E-74 T 31-10-2018 IPR012255 Electron transfer flavoprotein, beta subunit GO:0009055 Reactome: R-HSA-611105|Reactome: R-HSA-8876725 AF_0286 10281cdb88f8082d4d6010d681ba78af 247 SUPERFAMILY SSF52402 1 242 5.58E-67 T 31-10-2018 AF_0286 10281cdb88f8082d4d6010d681ba78af 247 Gene3D G3DSA:3.40.50.620 1 245 1.8E-75 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_0854 5292e0f0b86c771340852bc94ac8deff 128 Gene3D G3DSA:2.30.130.90 5 127 5.6E-6 T 31-10-2018 AF_0854 5292e0f0b86c771340852bc94ac8deff 128 Pfam PF13636 RNA-binding PUA-like domain of methyltransferase RsmF 82 125 2.6E-12 T 31-10-2018 IPR027391 rRNA small subunit methyltransferase F, RNA-binding PUA-like domain AF_1719 8c69a3c431f83ad4767397995be013b2 159 SUPERFAMILY SSF55021 78 158 5.27E-29 T 31-10-2018 AF_1719 8c69a3c431f83ad4767397995be013b2 159 SUPERFAMILY SSF55021 2 75 1.22E-24 T 31-10-2018 AF_1719 8c69a3c431f83ad4767397995be013b2 159 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 76 1.0E-35 T 31-10-2018 AF_1719 8c69a3c431f83ad4767397995be013b2 159 Gene3D G3DSA:3.30.70.260 1 79 1.1E-37 T 31-10-2018 AF_1719 8c69a3c431f83ad4767397995be013b2 159 TIGRFAM TIGR00119 acolac_sm: acetolactate synthase, small subunit 2 157 3.0E-74 T 31-10-2018 IPR004789 Acetolactate synthase, small subunit GO:0003984|GO:0009082 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AF_1719 8c69a3c431f83ad4767397995be013b2 159 Gene3D G3DSA:3.30.70.1150 82 159 8.1E-33 T 31-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal AF_1719 8c69a3c431f83ad4767397995be013b2 159 Pfam PF13710 ACT domain 12 73 4.0E-19 T 31-10-2018 AF_1719 8c69a3c431f83ad4767397995be013b2 159 Pfam PF10369 Small subunit of acetolactate synthase 83 156 1.4E-31 T 31-10-2018 IPR019455 Acetolactate synthase, small subunit, C-terminal KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AF_1368 412128e1027c37da3cc6f0d50fff43c4 221 Pfam PF02492 CobW/HypB/UreG, nucleotide-binding domain 32 191 7.8E-25 T 31-10-2018 IPR003495 CobW/HypB/UreG, nucleotide-binding domain AF_1368 412128e1027c37da3cc6f0d50fff43c4 221 TIGRFAM TIGR00073 hypB: hydrogenase accessory protein HypB 1 213 6.6E-99 T 31-10-2018 IPR004392 Hydrogenase maturation factor HypB GO:0016151|GO:0051604 AF_1368 412128e1027c37da3cc6f0d50fff43c4 221 Gene3D G3DSA:3.40.50.300 1 221 3.5E-60 T 31-10-2018 AF_1368 412128e1027c37da3cc6f0d50fff43c4 221 PIRSF PIRSF005624 1 221 1.3E-82 T 31-10-2018 IPR012202 [NiFe]-hydrogenase/urease maturation factor, Ni2-binding GTPase GO:0003924|GO:0016151 AF_1368 412128e1027c37da3cc6f0d50fff43c4 221 SUPERFAMILY SSF52540 8 213 3.78E-26 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0949 a29241e898155723a12315f677eba0ff 491 TIGRFAM TIGR00653 GlnA: glutamine synthetase, type I 15 490 3.5E-200 T 31-10-2018 IPR004809 Glutamine synthetase type I GO:0004356|GO:0005737|GO:0009399 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AF_0949 a29241e898155723a12315f677eba0ff 491 SMART SM01230 116 402 3.3E-115 T 31-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AF_0949 a29241e898155723a12315f677eba0ff 491 Gene3D G3DSA:3.30.590.10 119 478 1.8E-118 T 31-10-2018 AF_0949 a29241e898155723a12315f677eba0ff 491 Pfam PF00120 Glutamine synthetase, catalytic domain 117 488 3.9E-132 T 31-10-2018 IPR008146 Glutamine synthetase, catalytic domain GO:0004356|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AF_0949 a29241e898155723a12315f677eba0ff 491 Pfam PF03951 Glutamine synthetase, beta-Grasp domain 24 108 1.1E-21 T 31-10-2018 IPR008147 Glutamine synthetase, beta-Grasp domain GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AF_0949 a29241e898155723a12315f677eba0ff 491 Gene3D G3DSA:3.10.20.70 11 116 1.2E-25 T 31-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AF_0949 a29241e898155723a12315f677eba0ff 491 SUPERFAMILY SSF54368 14 113 2.49E-25 T 31-10-2018 IPR036651 Glutamine synthetase, N-terminal domain superfamily GO:0004356|GO:0006542|GO:0006807 KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964 AF_0949 a29241e898155723a12315f677eba0ff 491 SUPERFAMILY SSF55931 118 490 1.96E-117 T 31-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AF_0949 a29241e898155723a12315f677eba0ff 491 ProSitePatterns PS00181 Glutamine synthetase putative ATP-binding region signature. 276 291 - T 31-10-2018 IPR027303 Glutamine synthetase, glycine-rich site KEGG: 00220+6.3.1.2|KEGG: 00250+6.3.1.2|KEGG: 00630+6.3.1.2|KEGG: 00910+6.3.1.2|MetaCyc: PWY-381|MetaCyc: PWY-5675|MetaCyc: PWY-6549|MetaCyc: PWY-6963|MetaCyc: PWY-6964|Reactome: R-HSA-210455|Reactome: R-HSA-70614 AF_0757 adea62ff4ee1c04dee9b150645007619 177 Gene3D G3DSA:1.10.10.10 6 90 8.6E-20 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0757 adea62ff4ee1c04dee9b150645007619 177 PIRSF PIRSF006373 2 176 2.6E-59 T 31-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 AF_0757 adea62ff4ee1c04dee9b150645007619 177 SMART SM00531 22 160 7.2E-69 T 31-10-2018 IPR002853 Transcription initiation factor IIE subunit alpha, N-terminal GO:0006367 Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 AF_0757 adea62ff4ee1c04dee9b150645007619 177 TIGRFAM TIGR00373 TIGR00373: transcription factor E 10 170 3.4E-79 T 31-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 AF_0757 adea62ff4ee1c04dee9b150645007619 177 SUPERFAMILY SSF46785 14 89 1.14E-17 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0757 adea62ff4ee1c04dee9b150645007619 177 Pfam PF08271 TFIIB zinc-binding 118 159 4.0E-8 T 31-10-2018 IPR013137 Zinc finger, TFIIB-type AF_0757 adea62ff4ee1c04dee9b150645007619 177 Pfam PF02002 TFIIE alpha subunit 11 113 1.0E-37 T 31-10-2018 IPR024550 TFIIEalpha/SarR/Rpc3 HTH domain Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 AF_0757 adea62ff4ee1c04dee9b150645007619 177 Hamap MF_01909 Transcription factor E [tfe]. 7 170 25.111 T 31-10-2018 IPR016481 Transcription factor TFE, archaea GO:0006355 AF_1961 0c186db5da8ab3b7744075cca4b96020 332 Gene3D G3DSA:3.20.20.70 120 331 4.1E-15 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1961 0c186db5da8ab3b7744075cca4b96020 332 PIRSF PIRSF004869 22 332 8.2E-64 T 31-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted AF_1961 0c186db5da8ab3b7744075cca4b96020 332 Pfam PF04055 Radical SAM superfamily 125 268 1.5E-14 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_1961 0c186db5da8ab3b7744075cca4b96020 332 Pfam PF13353 4Fe-4S single cluster domain 124 211 1.1E-5 T 31-10-2018 AF_1961 0c186db5da8ab3b7744075cca4b96020 332 SUPERFAMILY SSF102114 126 326 1.31E-21 T 31-10-2018 AF_0981 4cc5fc2d4aacd97e1fe6d25d8352c02a 361 SMART SM00382 33 227 6.2E-19 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0981 4cc5fc2d4aacd97e1fe6d25d8352c02a 361 Pfam PF00005 ABC transporter 25 169 2.7E-36 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0981 4cc5fc2d4aacd97e1fe6d25d8352c02a 361 Gene3D G3DSA:3.40.50.300 9 285 8.1E-78 T 31-10-2018 AF_0981 4cc5fc2d4aacd97e1fe6d25d8352c02a 361 TIGRFAM TIGR01186 proV: glycine betaine/L-proline transport ATP binding subunit 18 290 4.1E-102 T 31-10-2018 IPR005892 Glycine betaine transport ATP-binding subunit GO:0005524|GO:0016020|GO:0031460 AF_0981 4cc5fc2d4aacd97e1fe6d25d8352c02a 361 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_0981 4cc5fc2d4aacd97e1fe6d25d8352c02a 361 SUPERFAMILY SSF52540 9 245 1.65E-80 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0981 4cc5fc2d4aacd97e1fe6d25d8352c02a 361 SUPERFAMILY SSF54631 254 357 5.11E-6 T 31-10-2018 AF_1262 a2dc1a1129955ac5804b32d5788e0a07 632 SUPERFAMILY SSF51395 2 362 3.67E-105 T 31-10-2018 AF_1262 a2dc1a1129955ac5804b32d5788e0a07 632 Gene3D G3DSA:3.50.50.60 471 588 1.3E-75 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1262 a2dc1a1129955ac5804b32d5788e0a07 632 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 375 600 3.9E-34 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AF_1262 a2dc1a1129955ac5804b32d5788e0a07 632 Gene3D G3DSA:3.40.50.720 376 626 1.3E-75 T 31-10-2018 AF_1262 a2dc1a1129955ac5804b32d5788e0a07 632 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 580 596 1.4E-18 T 31-10-2018 AF_1262 a2dc1a1129955ac5804b32d5788e0a07 632 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 377 396 1.4E-18 T 31-10-2018 AF_1262 a2dc1a1129955ac5804b32d5788e0a07 632 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 459 477 1.4E-18 T 31-10-2018 AF_1262 a2dc1a1129955ac5804b32d5788e0a07 632 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 497 515 1.4E-18 T 31-10-2018 AF_1262 a2dc1a1129955ac5804b32d5788e0a07 632 Gene3D G3DSA:3.20.20.70 1 369 1.9E-124 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1262 a2dc1a1129955ac5804b32d5788e0a07 632 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 2 330 6.0E-69 T 31-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 AF_1262 a2dc1a1129955ac5804b32d5788e0a07 632 SUPERFAMILY SSF51905 354 629 3.75E-50 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0506 7b90b4ca9388263747ab5a36e236f05d 366 SUPERFAMILY SSF46548 5 91 8.37E-18 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_0506 7b90b4ca9388263747ab5a36e236f05d 366 Pfam PF02754 Cysteine-rich domain 133 215 3.6E-19 T 31-10-2018 IPR004017 Cysteine-rich domain AF_0506 7b90b4ca9388263747ab5a36e236f05d 366 Pfam PF02754 Cysteine-rich domain 255 340 2.2E-20 T 31-10-2018 IPR004017 Cysteine-rich domain AF_0506 7b90b4ca9388263747ab5a36e236f05d 366 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 60 71 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0506 7b90b4ca9388263747ab5a36e236f05d 366 Gene3D G3DSA:3.30.70.3270 2 99 2.1E-7 T 31-10-2018 AF_0506 7b90b4ca9388263747ab5a36e236f05d 366 Pfam PF13534 4Fe-4S dicluster domain 9 74 9.6E-11 T 31-10-2018 AF_0232 542e648555b5b87ce99fcedcf5e9d896 224 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 37 218 9.4E-21 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AF_0232 542e648555b5b87ce99fcedcf5e9d896 224 Gene3D G3DSA:1.10.3720.10 6 220 3.0E-58 T 31-10-2018 IPR035906 MetI-like superfamily AF_0232 542e648555b5b87ce99fcedcf5e9d896 224 SUPERFAMILY SSF161098 18 204 5.1E-50 T 31-10-2018 IPR035906 MetI-like superfamily AF_0232 542e648555b5b87ce99fcedcf5e9d896 224 TIGRFAM TIGR01726 HEQRo_perm_3TM: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family 16 113 1.1E-31 T 31-10-2018 IPR010065 Amino acid ABC transporter, permease protein, 3-TM domain GO:0016021|GO:0022857|GO:0043190|GO:0071705 AF_0724 716880ad4c6c488818dc5d81ab73c285 446 SUPERFAMILY SSF53790 7 254 2.62E-51 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AF_0724 716880ad4c6c488818dc5d81ab73c285 446 PIRSF PIRSF004874 1 446 7.6E-242 T 31-10-2018 IPR014422 Cobalamin (vitamin B12) biosynthesis, bifunctional CbiH/CbiC GO:0009236 KEGG: 00860+5.4.99.60|MetaCyc: PWY-7377 AF_0724 716880ad4c6c488818dc5d81ab73c285 446 TIGRFAM TIGR01466 cobJ_cbiH: precorrin-3B C17-methyltransferase 10 243 2.9E-98 T 31-10-2018 IPR006363 Precorrin-3B C17-methyltransferase domain GO:0008168|GO:0009236 AF_0724 716880ad4c6c488818dc5d81ab73c285 446 Gene3D G3DSA:3.40.50.10230 261 446 2.4E-41 T 31-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 AF_0724 716880ad4c6c488818dc5d81ab73c285 446 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 9 214 5.7E-36 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AF_0724 716880ad4c6c488818dc5d81ab73c285 446 Gene3D G3DSA:3.30.950.10 118 245 8.5E-44 T 31-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AF_0724 716880ad4c6c488818dc5d81ab73c285 446 SUPERFAMILY SSF63965 260 441 2.35E-46 T 31-10-2018 IPR036588 Precorrin-8X methylmutase CobH/CbiC superfamily GO:0009236|GO:0016993 AF_0724 716880ad4c6c488818dc5d81ab73c285 446 Gene3D G3DSA:3.40.1010.10 4 117 7.8E-33 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AF_0724 716880ad4c6c488818dc5d81ab73c285 446 Pfam PF02570 Precorrin-8X methylmutase 269 440 7.6E-41 T 31-10-2018 IPR003722 Cobalamin biosynthesis precorrin-8X methylmutase CobH/CbiC GO:0009236|GO:0016993 AF_0241 93c5e13f5ff93a79ce3b18d82178699f 139 Pfam PF01980 Uncharacterised protein family UPF0066 18 129 1.2E-35 T 31-10-2018 IPR023370 YaeB-like, N-terminal domain AF_0241 93c5e13f5ff93a79ce3b18d82178699f 139 Gene3D G3DSA:2.40.30.70 1 139 7.8E-56 T 31-10-2018 IPR036414 YaeB, N-terminal domain superfamily AF_0241 93c5e13f5ff93a79ce3b18d82178699f 139 ProSitePatterns PS01318 TsaA-like domain signature. 77 88 - T 31-10-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site AF_0241 93c5e13f5ff93a79ce3b18d82178699f 139 SUPERFAMILY SSF118196 2 134 1.09E-46 T 31-10-2018 IPR036413 YaeB-like superfamily AF_0241 93c5e13f5ff93a79ce3b18d82178699f 139 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 1 135 5.3E-65 T 31-10-2018 IPR023370 YaeB-like, N-terminal domain AF_1097 c4b91a00624aa49b1726b044c48ffef3 448 SUPERFAMILY SSF53448 1 258 1.1E-64 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_1097 c4b91a00624aa49b1726b044c48ffef3 448 TIGRFAM TIGR01479 GMP_PMI: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase 3 446 1.2E-146 T 31-10-2018 IPR006375 Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase GO:0000271|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 AF_1097 c4b91a00624aa49b1726b044c48ffef3 448 Gene3D G3DSA:3.90.550.10 1 327 2.7E-106 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_1097 c4b91a00624aa49b1726b044c48ffef3 448 Pfam PF01050 Mannose-6-phosphate isomerase 293 443 2.5E-69 T 31-10-2018 IPR001538 Mannose-6-phosphate isomerase, type II, C-terminal GO:0005976|GO:0016779 KEGG: 00051+2.7.7.13|KEGG: 00520+2.7.7.13|MetaCyc: PWY-5659|MetaCyc: PWY-882 AF_1097 c4b91a00624aa49b1726b044c48ffef3 448 SUPERFAMILY SSF51182 180 447 1.3E-60 T 31-10-2018 IPR011051 RmlC-like cupin domain superfamily AF_1097 c4b91a00624aa49b1726b044c48ffef3 448 Pfam PF00483 Nucleotidyl transferase 2 264 2.9E-62 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AF_1097 c4b91a00624aa49b1726b044c48ffef3 448 Gene3D G3DSA:2.60.120.10 328 445 4.0E-19 T 31-10-2018 IPR014710 RmlC-like jelly roll fold AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 TIGRFAM TIGR03804 para_beta_helix: parallel beta-helix repeat 863 906 6.3E-5 T 31-10-2018 IPR022441 Parallel beta-helix repeat-2 Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00060 324 403 7.1E-9 T 31-10-2018 IPR003961 Fibronectin type III GO:0005515 AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00722 28 134 84.0 T 31-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00722 929 1039 0.85 T 31-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00722 386 511 14.0 T 31-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00722 135 290 1.3E-7 T 31-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00722 810 928 0.0029 T 31-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00722 518 689 0.01 T 31-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00710 186 208 3.5 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00710 491 522 620.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00710 163 184 81.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00710 964 986 1300.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00710 663 690 2000.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00710 141 162 4.8 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00710 869 891 710.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00710 892 929 2100.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00710 587 609 3400.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00710 113 135 2.1 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00710 541 561 500.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00710 797 818 630.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00710 842 868 7.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00710 930 963 2100.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00710 616 641 1400.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SMART SM00710 691 712 2300.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 Pfam PF05048 Periplasmic copper-binding protein (NosD) 807 1050 1.3E-48 T 31-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 Pfam PF05048 Periplasmic copper-binding protein (NosD) 72 279 6.3E-30 T 31-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 Pfam PF05048 Periplasmic copper-binding protein (NosD) 442 642 4.3E-6 T 31-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 Gene3D G3DSA:2.60.40.10 319 415 6.0E-10 T 31-10-2018 IPR013783 Immunoglobulin-like fold AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SUPERFAMILY SSF51126 411 739 9.86E-29 T 31-10-2018 IPR011050 Pectin lyase fold/virulence factor AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 Gene3D G3DSA:2.160.20.10 775 917 9.5E-12 T 31-10-2018 IPR012334 Pectin lyase fold AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SUPERFAMILY SSF49265 317 417 9.51E-10 T 31-10-2018 IPR036116 Fibronectin type III superfamily GO:0005515 AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SUPERFAMILY SSF51126 775 1048 6.28E-20 T 31-10-2018 IPR011050 Pectin lyase fold/virulence factor AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 SUPERFAMILY SSF51126 35 277 1.4E-33 T 31-10-2018 IPR011050 Pectin lyase fold/virulence factor AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 Gene3D G3DSA:2.160.20.10 421 774 2.5E-16 T 31-10-2018 IPR012334 Pectin lyase fold AF_1413 2316fde9fbb0db799084f616ce23eeae 2425 Gene3D G3DSA:2.160.20.10 54 278 2.1E-19 T 31-10-2018 IPR012334 Pectin lyase fold AF_0871 d500ae88b944cb8274a054bf20ca979f 335 Hamap MF_00394 Glycerol-3-phosphate dehydrogenase [NAD(P)+] [gpsA]. 1 330 28.342 T 31-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AF_0871 d500ae88b944cb8274a054bf20ca979f 335 SUPERFAMILY SSF48179 181 331 3.91E-37 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_0871 d500ae88b944cb8274a054bf20ca979f 335 Pfam PF07479 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus 181 327 2.3E-35 T 31-10-2018 IPR006109 Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal GO:0004367|GO:0005975|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AF_0871 d500ae88b944cb8274a054bf20ca979f 335 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 174 198 1.6E-16 T 31-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AF_0871 d500ae88b944cb8274a054bf20ca979f 335 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 244 261 1.6E-16 T 31-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AF_0871 d500ae88b944cb8274a054bf20ca979f 335 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 5 22 1.6E-16 T 31-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AF_0871 d500ae88b944cb8274a054bf20ca979f 335 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 134 154 1.6E-16 T 31-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AF_0871 d500ae88b944cb8274a054bf20ca979f 335 SUPERFAMILY SSF51735 1 179 2.01E-45 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0871 d500ae88b944cb8274a054bf20ca979f 335 PIRSF PIRSF000114 1 335 1.4E-81 T 31-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AF_0871 d500ae88b944cb8274a054bf20ca979f 335 Pfam PF01210 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus 3 160 6.9E-20 T 31-10-2018 IPR011128 Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal GO:0016616|GO:0046168|GO:0051287|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AF_0871 d500ae88b944cb8274a054bf20ca979f 335 Gene3D G3DSA:1.10.1040.10 181 335 7.4E-54 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AF_0871 d500ae88b944cb8274a054bf20ca979f 335 Gene3D G3DSA:3.40.50.720 1 180 1.0E-61 T 31-10-2018 AF_0729 f824e029a33562827e11d66f593b3f25 87 TIGRFAM TIGR01165 cbiN: cobalt transport protein 4 80 5.5E-39 T 31-10-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 AF_0729 f824e029a33562827e11d66f593b3f25 87 Pfam PF02553 Cobalt transport protein component CbiN 4 65 7.9E-27 T 31-10-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 AF_0729 f824e029a33562827e11d66f593b3f25 87 Hamap MF_00330 Cobalt transport protein CbiN [cbiN]. 1 87 38.407 T 31-10-2018 IPR003705 Cobalt transport protein CbiN GO:0006824|GO:0009236|GO:0015087|GO:0016020 AF_1724 0565e3805a5cc08cf596b2ea861bb145 305 Pfam PF03747 ADP-ribosylglycohydrolase 8 269 1.0E-69 T 31-10-2018 IPR005502 ADP-ribosylation/Crystallin J1 AF_1724 0565e3805a5cc08cf596b2ea861bb145 305 Gene3D G3DSA:1.10.4080.10 1 303 7.8E-88 T 31-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily AF_1724 0565e3805a5cc08cf596b2ea861bb145 305 SUPERFAMILY SSF101478 2 298 8.89E-81 T 31-10-2018 IPR036705 ADP-ribosylation/Crystallin J1 superfamily AF_1377 83e1edc20265e94354afe8fed9f0dcbc 659 Gene3D G3DSA:3.50.50.60 423 578 5.1E-7 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1377 83e1edc20265e94354afe8fed9f0dcbc 659 Pfam PF12838 4Fe-4S dicluster domain 239 321 7.2E-10 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1377 83e1edc20265e94354afe8fed9f0dcbc 659 Gene3D G3DSA:3.30.70.20 617 657 3.1E-6 T 31-10-2018 AF_1377 83e1edc20265e94354afe8fed9f0dcbc 659 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 240 251 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1377 83e1edc20265e94354afe8fed9f0dcbc 659 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 598 609 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1377 83e1edc20265e94354afe8fed9f0dcbc 659 Gene3D G3DSA:3.50.50.60 130 237 1.1E-12 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1377 83e1edc20265e94354afe8fed9f0dcbc 659 Gene3D G3DSA:3.30.70.20 238 325 1.7E-14 T 31-10-2018 AF_1377 83e1edc20265e94354afe8fed9f0dcbc 659 Pfam PF12831 FAD dependent oxidoreductase 141 176 4.2E-8 T 31-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal AF_1377 83e1edc20265e94354afe8fed9f0dcbc 659 Pfam PF14697 4Fe-4S dicluster domain 591 641 7.5E-9 T 31-10-2018 AF_1377 83e1edc20265e94354afe8fed9f0dcbc 659 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 626 637 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1377 83e1edc20265e94354afe8fed9f0dcbc 659 Gene3D G3DSA:3.30.70.20 579 616 3.4E-8 T 31-10-2018 AF_1377 83e1edc20265e94354afe8fed9f0dcbc 659 SUPERFAMILY SSF54862 232 643 4.49E-25 T 31-10-2018 AF_1377 83e1edc20265e94354afe8fed9f0dcbc 659 SUPERFAMILY SSF51971 140 580 4.59E-28 T 31-10-2018 AF_0768 214af2e7c6c512667aafa4e4eff94b86 595 Pfam PF11987 Translation-initiation factor 2 346 445 1.2E-21 T 31-10-2018 IPR023115 Translation initiation factor IF- 2, domain 3 AF_0768 214af2e7c6c512667aafa4e4eff94b86 595 TIGRFAM TIGR00491 aIF-2: translation initiation factor aIF-2 11 595 2.0E-292 T 31-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 AF_0768 214af2e7c6c512667aafa4e4eff94b86 595 SUPERFAMILY SSF52156 337 453 3.53E-29 T 31-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily AF_0768 214af2e7c6c512667aafa4e4eff94b86 595 PRINTS PR00315 GTP-binding elongation factor signature 130 139 2.1E-10 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_0768 214af2e7c6c512667aafa4e4eff94b86 595 PRINTS PR00315 GTP-binding elongation factor signature 15 28 2.1E-10 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_0768 214af2e7c6c512667aafa4e4eff94b86 595 PRINTS PR00315 GTP-binding elongation factor signature 94 105 2.1E-10 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_0768 214af2e7c6c512667aafa4e4eff94b86 595 PRINTS PR00315 GTP-binding elongation factor signature 78 88 2.1E-10 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_0768 214af2e7c6c512667aafa4e4eff94b86 595 Gene3D G3DSA:3.40.50.300 10 230 1.1E-64 T 31-10-2018 AF_0768 214af2e7c6c512667aafa4e4eff94b86 595 SUPERFAMILY SSF52540 11 295 6.33E-53 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0768 214af2e7c6c512667aafa4e4eff94b86 595 Gene3D G3DSA:3.40.50.10050 353 458 1.3E-31 T 31-10-2018 IPR036925 Translation initiation factor IF-2, domain 3 superfamily AF_0768 214af2e7c6c512667aafa4e4eff94b86 595 Pfam PF00009 Elongation factor Tu GTP binding domain 14 220 9.7E-35 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_0768 214af2e7c6c512667aafa4e4eff94b86 595 Hamap MF_00100_A Translation initiation factor IF-2 [infB]. 9 595 43.201 T 31-10-2018 IPR004544 Translation initiation factor aIF-2, archaea GO:0003743|GO:0005525|GO:0005622|GO:0006413 AF_0768 214af2e7c6c512667aafa4e4eff94b86 595 Pfam PF03144 Elongation factor Tu domain 2 251 326 1.5E-9 T 31-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AF_0768 214af2e7c6c512667aafa4e4eff94b86 595 SUPERFAMILY SSF50447 466 591 1.32E-25 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AF_0768 214af2e7c6c512667aafa4e4eff94b86 595 Gene3D G3DSA:2.40.30.10 467 555 7.4E-31 T 31-10-2018 AF_0768 214af2e7c6c512667aafa4e4eff94b86 595 Pfam PF14578 Elongation factor Tu domain 4 467 552 9.7E-28 T 31-10-2018 IPR029459 Elongation factor Tu-type domain AF_0768 214af2e7c6c512667aafa4e4eff94b86 595 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 14 153 1.7E-19 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AF_0768 214af2e7c6c512667aafa4e4eff94b86 595 Gene3D G3DSA:2.40.30.10 236 352 9.4E-40 T 31-10-2018 AF_0479 73649bec349c12e7fd0817bbe14146b8 355 Gene3D G3DSA:3.30.420.190 146 355 1.2E-64 T 31-10-2018 AF_0479 73649bec349c12e7fd0817bbe14146b8 355 TIGRFAM TIGR03123 one_C_unchar_1: probable H4MPT-linked C1 transfer pathway protein 44 352 3.4E-122 T 31-10-2018 IPR002756 4-[[4-(2-aminoethyl)phenoxy]-methyl]-2-furanmethanamine-glutamate synthase KEGG: 00680+2.5.1.131|MetaCyc: PWY-5254 AF_0479 73649bec349c12e7fd0817bbe14146b8 355 Pfam PF01968 Hydantoinase/oxoprolinase 93 337 2.7E-23 T 31-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 AF_0479 73649bec349c12e7fd0817bbe14146b8 355 Gene3D G3DSA:3.30.420.40 43 145 3.2E-24 T 31-10-2018 AF_1558 fe37a73bd3cb93c9b4a234396510fa9f 1156 TIGRFAM TIGR02169 SMC_prok_A: chromosome segregation protein SMC 2 1154 0.0 T 31-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 AF_1558 fe37a73bd3cb93c9b4a234396510fa9f 1156 SUPERFAMILY SSF75553 475 664 1.19E-50 T 31-10-2018 IPR036277 SMCs flexible hinge superfamily GO:0005515|GO:0005524|GO:0005694|GO:0051276 AF_1558 fe37a73bd3cb93c9b4a234396510fa9f 1156 SMART SM00968 515 632 1.5E-42 T 31-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 AF_1558 fe37a73bd3cb93c9b4a234396510fa9f 1156 Pfam PF02463 RecF/RecN/SMC N terminal domain 2 1147 1.2E-60 T 31-10-2018 IPR003395 RecF/RecN/SMC, N-terminal AF_1558 fe37a73bd3cb93c9b4a234396510fa9f 1156 Gene3D G3DSA:1.20.5.340 669 784 1.4E-5 T 31-10-2018 AF_1558 fe37a73bd3cb93c9b4a234396510fa9f 1156 SUPERFAMILY SSF52540 1 1146 1.01E-44 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1558 fe37a73bd3cb93c9b4a234396510fa9f 1156 Hamap MF_01894 Chromosome partition protein Smc [smc]. 1 1156 19.998 T 31-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 AF_1558 fe37a73bd3cb93c9b4a234396510fa9f 1156 Gene3D G3DSA:3.40.50.300 1003 1156 5.1E-44 T 31-10-2018 AF_1558 fe37a73bd3cb93c9b4a234396510fa9f 1156 Gene3D G3DSA:3.30.70.1620 575 658 1.1E-53 T 31-10-2018 AF_1558 fe37a73bd3cb93c9b4a234396510fa9f 1156 SUPERFAMILY SSF58104 686 894 1.52E-6 T 31-10-2018 AF_1558 fe37a73bd3cb93c9b4a234396510fa9f 1156 Gene3D G3DSA:1.20.1060.20 495 666 1.1E-53 T 31-10-2018 AF_1558 fe37a73bd3cb93c9b4a234396510fa9f 1156 PIRSF PIRSF005719 1 1156 2.4E-277 T 31-10-2018 IPR024704 Structural maintenance of chromosomes protein AF_1558 fe37a73bd3cb93c9b4a234396510fa9f 1156 Gene3D G3DSA:3.40.50.300 1 242 2.7E-47 T 31-10-2018 AF_1558 fe37a73bd3cb93c9b4a234396510fa9f 1156 Pfam PF06470 SMC proteins Flexible Hinge Domain 515 631 2.0E-33 T 31-10-2018 IPR010935 SMCs flexible hinge GO:0005515|GO:0005524|GO:0005694|GO:0051276 AF_1558 fe37a73bd3cb93c9b4a234396510fa9f 1156 TIGRFAM TIGR02168 SMC_prok_B: chromosome segregation protein SMC 3 1154 4.8E-197 T 31-10-2018 IPR011890 Structural maintenance of chromosomes protein, prokaryotic GO:0007062|GO:0030261 AF_1459 e01965a13402b4e507dc35b5844a6e12 90 Pfam PF14947 Winged helix-turn-helix 3 85 1.3E-18 T 31-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain AF_1459 e01965a13402b4e507dc35b5844a6e12 90 SUPERFAMILY SSF46785 4 88 2.3E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1459 e01965a13402b4e507dc35b5844a6e12 90 Gene3D G3DSA:1.10.10.10 1 89 1.2E-24 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1080 e351dde81a1123949c1379a1aa6ee0f1 86 Gene3D G3DSA:3.30.2310.20 6 79 8.0E-7 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AF_1080 e351dde81a1123949c1379a1aa6ee0f1 86 SUPERFAMILY SSF143011 8 70 2.04E-8 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AF_1644 68494e0c8702785f3abeca4ea79f42ee 438 SUPERFAMILY SSF54862 28 330 2.37E-28 T 31-10-2018 AF_1644 68494e0c8702785f3abeca4ea79f42ee 438 Gene3D G3DSA:3.30.70.20 12 57 3.9E-7 T 31-10-2018 AF_1644 68494e0c8702785f3abeca4ea79f42ee 438 Pfam PF12838 4Fe-4S dicluster domain 198 253 5.7E-10 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1644 68494e0c8702785f3abeca4ea79f42ee 438 Pfam PF12838 4Fe-4S dicluster domain 35 88 6.3E-10 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1644 68494e0c8702785f3abeca4ea79f42ee 438 PIRSF PIRSF005658 4 380 6.5E-158 T 31-10-2018 AF_1644 68494e0c8702785f3abeca4ea79f42ee 438 Gene3D G3DSA:3.30.70.20 218 260 1.2E-5 T 31-10-2018 AF_1644 68494e0c8702785f3abeca4ea79f42ee 438 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 117 128 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1644 68494e0c8702785f3abeca4ea79f42ee 438 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 239 250 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1644 68494e0c8702785f3abeca4ea79f42ee 438 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 308 319 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1644 68494e0c8702785f3abeca4ea79f42ee 438 Gene3D G3DSA:3.30.70.20 58 135 1.8E-13 T 31-10-2018 AF_1644 68494e0c8702785f3abeca4ea79f42ee 438 Gene3D G3DSA:3.30.70.20 136 217 4.5E-15 T 31-10-2018 AF_1644 68494e0c8702785f3abeca4ea79f42ee 438 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 74 85 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1644 68494e0c8702785f3abeca4ea79f42ee 438 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 35 46 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1644 68494e0c8702785f3abeca4ea79f42ee 438 Pfam PF00037 4Fe-4S binding domain 302 323 7.8E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1644 68494e0c8702785f3abeca4ea79f42ee 438 Pfam PF13237 4Fe-4S dicluster domain 112 171 4.0E-6 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1644 68494e0c8702785f3abeca4ea79f42ee 438 Gene3D G3DSA:3.30.70.20 269 371 3.2E-9 T 31-10-2018 AF_0528 5de520a5bd656686ccaa738057f28de1 232 Gene3D G3DSA:3.40.50.80 84 190 3.1E-23 T 31-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AF_0528 5de520a5bd656686ccaa738057f28de1 232 PIRSF PIRSF006816 1 232 7.5E-74 T 31-10-2018 IPR012165 Cytochrome-c3 hydrogenase, gamma subunit GO:0006221|GO:0050660|GO:0051537 AF_0528 5de520a5bd656686ccaa738057f28de1 232 Hamap MF_01211 Dihydroorotate dehydrogenase B (NAD(+)), electron transfer subunit [pyrK]. 1 232 33.526 T 31-10-2018 IPR023455 Dihydroorotate dehydrogenase electron transfer subunit AF_0528 5de520a5bd656686ccaa738057f28de1 232 SUPERFAMILY SSF52343 82 230 6.42E-32 T 31-10-2018 IPR039261 Ferredoxin-NADP reductase (FNR), nucleotide-binding domain AF_0528 5de520a5bd656686ccaa738057f28de1 232 Pfam PF10418 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B 197 230 3.2E-13 T 31-10-2018 IPR019480 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain AF_0528 5de520a5bd656686ccaa738057f28de1 232 Gene3D G3DSA:2.40.30.10 1 83 4.0E-7 T 31-10-2018 AF_0528 5de520a5bd656686ccaa738057f28de1 232 SUPERFAMILY SSF63380 2 84 4.12E-15 T 31-10-2018 IPR017938 Riboflavin synthase-like beta-barrel AF_0528 5de520a5bd656686ccaa738057f28de1 232 Gene3D G3DSA:2.10.240.10 197 231 2.9E-9 T 31-10-2018 IPR037117 Dihydroorotate dehydrogenase, electron transfer subunit, Fe-S binding domain superfamily AF_0528 5de520a5bd656686ccaa738057f28de1 232 Pfam PF00175 Oxidoreductase NAD-binding domain 93 179 6.8E-8 T 31-10-2018 IPR001433 Oxidoreductase FAD/NAD(P)-binding GO:0016491|GO:0055114 AF_0159 1e179e4184bf904408f2db2776879cf5 1134 Gene3D G3DSA:3.40.50.740 597 725 2.4E-12 T 31-10-2018 AF_0159 1e179e4184bf904408f2db2776879cf5 1134 SUPERFAMILY SSF50692 925 1017 2.07E-22 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AF_0159 1e179e4184bf904408f2db2776879cf5 1134 SUPERFAMILY SSF53706 47 931 1.48E-112 T 31-10-2018 AF_0159 1e179e4184bf904408f2db2776879cf5 1134 Gene3D G3DSA:2.40.40.20 898 1042 9.4E-20 T 31-10-2018 AF_0159 1e179e4184bf904408f2db2776879cf5 1134 Pfam PF00384 Molybdopterin oxidoreductase 321 710 4.7E-16 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_0159 1e179e4184bf904408f2db2776879cf5 1134 Pfam PF01568 Molydopterin dinucleotide binding domain 951 1011 9.1E-13 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AF_0159 1e179e4184bf904408f2db2776879cf5 1134 Gene3D G3DSA:3.40.50.740 38 202 2.3E-15 T 31-10-2018 AF_0159 1e179e4184bf904408f2db2776879cf5 1134 SMART SM00926 46 131 1.5E-13 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_0547 2540de92c3671edddc666ab93b58a691 477 SUPERFAMILY SSF46548 57 169 7.85E-14 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_0547 2540de92c3671edddc666ab93b58a691 477 Pfam PF13183 4Fe-4S dicluster domain 68 154 2.0E-9 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0547 2540de92c3671edddc666ab93b58a691 477 Pfam PF02754 Cysteine-rich domain 359 451 5.9E-20 T 31-10-2018 IPR004017 Cysteine-rich domain AF_0547 2540de92c3671edddc666ab93b58a691 477 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 141 152 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1545 b831585ff3fdc5951de5b25f59958fac 235 Pfam PF04254 Protein of unknown function (DUF432) 56 178 1.9E-48 T 31-10-2018 IPR007366 Protein of unknown function DUF432 AF_1545 b831585ff3fdc5951de5b25f59958fac 235 PIRSF PIRSF019202 1 235 6.7E-100 T 31-10-2018 IPR007366 Protein of unknown function DUF432 AF_1180 b5f8efc1b27d33c11f723e106f04e459 434 SUPERFAMILY SSF56024 283 404 3.14E-18 T 31-10-2018 AF_1180 b5f8efc1b27d33c11f723e106f04e459 434 Pfam PF13091 PLD-like domain 287 404 6.6E-17 T 31-10-2018 IPR025202 Phospholipase D-like domain Reactome: R-HSA-1483148|Reactome: R-HSA-1483166 AF_1180 b5f8efc1b27d33c11f723e106f04e459 434 Gene3D G3DSA:3.30.870.10 281 405 1.9E-21 T 31-10-2018 AF_1808 9afb13c386169384c30ccb09fe4f456f 75 Pfam PF14947 Winged helix-turn-helix 14 74 3.8E-6 T 31-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain AF_1808 9afb13c386169384c30ccb09fe4f456f 75 SUPERFAMILY SSF46785 10 73 1.31E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1808 9afb13c386169384c30ccb09fe4f456f 75 Gene3D G3DSA:1.10.10.10 2 72 2.0E-8 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0459 80d6882b9364e87db0f12cf81916d25e 736 Pfam PF03176 MMPL family 109 363 2.3E-24 T 31-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AF_0459 80d6882b9364e87db0f12cf81916d25e 736 Pfam PF03176 MMPL family 509 723 2.9E-30 T 31-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AF_0459 80d6882b9364e87db0f12cf81916d25e 736 Gene3D G3DSA:1.20.1640.10 539 729 1.6E-14 T 31-10-2018 AF_0459 80d6882b9364e87db0f12cf81916d25e 736 SUPERFAMILY SSF82866 529 724 3.27E-33 T 31-10-2018 AF_0459 80d6882b9364e87db0f12cf81916d25e 736 SUPERFAMILY SSF82866 150 364 1.12E-31 T 31-10-2018 AF_0459 80d6882b9364e87db0f12cf81916d25e 736 TIGRFAM TIGR00921 2A067: efflux transporter, putative, hydrophobe/amphiphile efflux-3 (HAE3) family 24 723 1.3E-177 T 31-10-2018 IPR004767 Hydrophobe/amphiphile efflux-3 HAE3 AF_0459 80d6882b9364e87db0f12cf81916d25e 736 Gene3D G3DSA:1.20.1640.10 185 372 1.0E-13 T 31-10-2018 AF_0786 e20d82cebb41f8ba84010d610ec54996 351 Gene3D G3DSA:3.30.460.20 18 159 9.8E-51 T 31-10-2018 AF_0786 e20d82cebb41f8ba84010d610ec54996 351 Gene3D G3DSA:1.20.58.340 274 351 1.3E-35 T 31-10-2018 AF_0786 e20d82cebb41f8ba84010d610ec54996 351 Pfam PF01544 CorA-like Mg2+ transporter protein 65 347 1.8E-74 T 31-10-2018 IPR002523 Mg2+ transporter protein, CorA-like/Zinc transport protein ZntB GO:0016020|GO:0030001|GO:0046873|GO:0055085 AF_0786 e20d82cebb41f8ba84010d610ec54996 351 TIGRFAM TIGR00383 corA: magnesium and cobalt transport protein CorA 33 351 1.4E-128 T 31-10-2018 IPR004488 Magnesium/cobalt transport protein CorA GO:0006824|GO:0015087|GO:0015095|GO:0015693|GO:0016020 AF_0786 e20d82cebb41f8ba84010d610ec54996 351 SUPERFAMILY SSF143865 10 285 1.09E-69 T 31-10-2018 AF_0786 e20d82cebb41f8ba84010d610ec54996 351 Gene3D G3DSA:1.20.58.340 160 263 1.9E-37 T 31-10-2018 AF_0786 e20d82cebb41f8ba84010d610ec54996 351 SUPERFAMILY SSF144083 286 349 1.26E-23 T 31-10-2018 AF_1523 2a3f762315fcec1e767f0018b9b5acd4 103 Pfam PF04266 ASCH domain 5 103 1.9E-16 T 31-10-2018 IPR007374 ASCH domain AF_1523 2a3f762315fcec1e767f0018b9b5acd4 103 SUPERFAMILY SSF88697 3 102 3.73E-18 T 31-10-2018 IPR015947 PUA-like superfamily AF_1523 2a3f762315fcec1e767f0018b9b5acd4 103 SMART SM01022 4 103 1.5E-21 T 31-10-2018 IPR007374 ASCH domain AF_2407 983e3d17a1ce339c758377d15c44e2bc 203 SUPERFAMILY SSF56281 2 201 5.55E-39 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_2407 983e3d17a1ce339c758377d15c44e2bc 203 SMART SM00849 19 180 4.5E-28 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_2407 983e3d17a1ce339c758377d15c44e2bc 203 Gene3D G3DSA:3.60.15.10 1 202 2.0E-37 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_2407 983e3d17a1ce339c758377d15c44e2bc 203 Pfam PF00753 Metallo-beta-lactamase superfamily 18 78 2.7E-7 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_2407 983e3d17a1ce339c758377d15c44e2bc 203 Pfam PF00753 Metallo-beta-lactamase superfamily 105 180 9.6E-10 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_0492 e5da07099a34666258e24d777ee6495e 223 Gene3D G3DSA:2.40.50.140 50 136 2.7E-35 T 31-10-2018 AF_0492 e5da07099a34666258e24d777ee6495e 223 SMART SM00322 134 198 2.8E-8 T 31-10-2018 IPR004087 K Homology domain GO:0003676 AF_0492 e5da07099a34666258e24d777ee6495e 223 SUPERFAMILY SSF54791 137 214 2.67E-17 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AF_0492 e5da07099a34666258e24d777ee6495e 223 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 4 36 2.3E-6 T 31-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AF_0492 e5da07099a34666258e24d777ee6495e 223 Pfam PF00575 S1 RNA binding domain 55 126 9.3E-8 T 31-10-2018 IPR003029 S1 domain GO:0003676 AF_0492 e5da07099a34666258e24d777ee6495e 223 SUPERFAMILY SSF110324 2 51 2.15E-12 T 31-10-2018 AF_0492 e5da07099a34666258e24d777ee6495e 223 Pfam PF15985 KH domain 137 182 9.3E-7 T 31-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 AF_0492 e5da07099a34666258e24d777ee6495e 223 Gene3D G3DSA:2.40.50.100 1 49 3.4E-19 T 31-10-2018 AF_0492 e5da07099a34666258e24d777ee6495e 223 SUPERFAMILY SSF50249 51 139 3.21E-22 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0492 e5da07099a34666258e24d777ee6495e 223 Gene3D G3DSA:3.30.1370.10 137 223 1.6E-37 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AF_0492 e5da07099a34666258e24d777ee6495e 223 SMART SM00316 56 127 2.6E-17 T 31-10-2018 IPR022967 RNA-binding domain, S1 AF_0492 e5da07099a34666258e24d777ee6495e 223 Hamap MF_00623 Exosome complex component Rrp4 [rrp4]. 1 219 35.922 T 31-10-2018 IPR023474 Exosome complex component Rrp4 GO:0000178|GO:0008143 AF_2107 d0f5f97f675efab843b3cf2031d80c06 238 Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. 1 230 36.152 T 31-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AF_2107 d0f5f97f675efab843b3cf2031d80c06 238 SUPERFAMILY SSF55821 4 225 6.18E-62 T 31-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AF_2107 d0f5f97f675efab843b3cf2031d80c06 238 TIGRFAM TIGR00506 ribB: 3,4-dihydroxy-2-butanone-4-phosphate synthase 1 226 2.8E-84 T 31-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AF_2107 d0f5f97f675efab843b3cf2031d80c06 238 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 6 224 2.4E-56 T 31-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AF_2107 d0f5f97f675efab843b3cf2031d80c06 238 Gene3D G3DSA:3.90.870.10 4 231 1.6E-70 T 31-10-2018 AF_2211 85fcb93e4a8d75a411bd0b32e69f899e 160 Gene3D G3DSA:3.30.428.10 1 160 2.8E-53 T 31-10-2018 IPR036265 HIT-like superfamily AF_2211 85fcb93e4a8d75a411bd0b32e69f899e 160 SUPERFAMILY SSF54197 1 150 7.58E-42 T 31-10-2018 IPR036265 HIT-like superfamily AF_2211 85fcb93e4a8d75a411bd0b32e69f899e 160 Pfam PF01230 HIT domain 34 125 2.4E-15 T 31-10-2018 IPR001310 Histidine triad (HIT) protein AF_1131 6dfcb592041ec2d84009cedeaa2203b0 75 Hamap MF_00192 DNA-directed RNA polymerase subunit K [rpoK]. 9 63 21.208 T 31-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AF_1131 6dfcb592041ec2d84009cedeaa2203b0 75 PIRSF PIRSF000778 4 68 4.1E-26 T 31-10-2018 IPR006111 Archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AF_1131 6dfcb592041ec2d84009cedeaa2203b0 75 ProSitePatterns PS01111 RNA polymerases K / 14 to 18 Kd subunits signature. 12 26 - T 31-10-2018 IPR020708 DNA-directed RNA polymerase, 14-18kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AF_1131 6dfcb592041ec2d84009cedeaa2203b0 75 Pfam PF01192 RNA polymerase Rpb6 12 57 7.7E-13 T 31-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AF_1131 6dfcb592041ec2d84009cedeaa2203b0 75 SMART SM01409 5 57 3.2E-5 T 31-10-2018 IPR006110 RNA polymerase, subunit omega/K/RPB6 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AF_1131 6dfcb592041ec2d84009cedeaa2203b0 75 SUPERFAMILY SSF63562 10 62 1.14E-21 T 31-10-2018 IPR036161 RPB6/omega subunit-like superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AF_1131 6dfcb592041ec2d84009cedeaa2203b0 75 Gene3D G3DSA:3.90.940.50 9 62 2.6E-26 T 31-10-2018 AF_1987 8f464a2cdbb8a4d52f85532e6fc1b153 216 SUPERFAMILY SSF46785 172 213 1.16E-5 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1987 8f464a2cdbb8a4d52f85532e6fc1b153 216 Gene3D G3DSA:1.10.10.10 133 215 7.7E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1098 9e1c38411f3803e9576b4cefd7082f34 180 Gene3D G3DSA:3.20.130.10 1 180 9.2E-85 T 31-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 AF_1098 9e1c38411f3803e9576b4cefd7082f34 180 TIGRFAM TIGR00723 ttdB_fumA_fumB: hydrolyase, tartrate beta subunit/fumarate domain protein, Fe-S type 15 180 5.3E-78 T 31-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 AF_1098 9e1c38411f3803e9576b4cefd7082f34 180 SUPERFAMILY SSF117457 4 178 1.16E-64 T 31-10-2018 IPR036660 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain superfamily GO:0016836 AF_1098 9e1c38411f3803e9576b4cefd7082f34 180 Pfam PF05683 Fumarase C-terminus 8 179 1.7E-50 T 31-10-2018 IPR004647 Fe-S hydro-lyase, tartrate dehydratase beta-type, catalytic domain GO:0016836 AF_0953 ecd2835d113bf65ded86cf18e9497590 511 PIRSF PIRSF500061 6 511 4.7E-203 T 31-10-2018 AF_0953 ecd2835d113bf65ded86cf18e9497590 511 PIRSF PIRSF006429 8 511 1.1E-144 T 31-10-2018 IPR024188 Glutamate synthase large subunit-like protein AF_0953 ecd2835d113bf65ded86cf18e9497590 511 SUPERFAMILY SSF51395 97 495 1.61E-118 T 31-10-2018 AF_0953 ecd2835d113bf65ded86cf18e9497590 511 SUPERFAMILY SSF54862 13 148 1.13E-17 T 31-10-2018 AF_0953 ecd2835d113bf65ded86cf18e9497590 511 Gene3D G3DSA:3.20.20.70 135 503 2.4E-131 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0953 ecd2835d113bf65ded86cf18e9497590 511 Pfam PF00037 4Fe-4S binding domain 51 70 2.3E-6 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0953 ecd2835d113bf65ded86cf18e9497590 511 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 55 66 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0953 ecd2835d113bf65ded86cf18e9497590 511 Gene3D G3DSA:3.30.70.20 7 89 1.7E-8 T 31-10-2018 AF_0953 ecd2835d113bf65ded86cf18e9497590 511 Pfam PF01645 Conserved region in glutamate synthase 113 479 7.8E-147 T 31-10-2018 IPR002932 Glutamate synthase domain GO:0006537|GO:0015930|GO:0016638|GO:0055114 AF_1437 a837b33b5c73ef6cc315e3a85b3d4393 308 Gene3D G3DSA:3.40.50.1000 2 257 2.4E-101 T 31-10-2018 IPR023214 HAD superfamily AF_1437 a837b33b5c73ef6cc315e3a85b3d4393 308 SUPERFAMILY SSF56784 1 263 1.11E-42 T 31-10-2018 IPR036412 HAD-like superfamily AF_1437 a837b33b5c73ef6cc315e3a85b3d4393 308 Gene3D G3DSA:1.20.5.1100 281 308 6.8E-20 T 31-10-2018 AF_1437 a837b33b5c73ef6cc315e3a85b3d4393 308 PIRSF PIRSF019370 1 308 3.4E-144 T 31-10-2018 IPR024196 [NiFe]-hydrogenase-3-type complex Eha, EhaR AF_1437 a837b33b5c73ef6cc315e3a85b3d4393 308 Gene3D G3DSA:1.10.3870.10 14 182 2.4E-101 T 31-10-2018 AF_0264 a32035d6bb63b74e3c129fe87edfce58 336 TIGRFAM TIGR03674 fen_arch: flap structure-specific endonuclease 1 336 1.7E-158 T 31-10-2018 IPR019973 Flap structure-specific endonuclease, archaea GO:0016788 AF_0264 a32035d6bb63b74e3c129fe87edfce58 336 Gene3D G3DSA:1.10.150.20 220 281 3.7E-23 T 31-10-2018 AF_0264 a32035d6bb63b74e3c129fe87edfce58 336 SUPERFAMILY SSF88723 6 235 5.61E-60 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_0264 a32035d6bb63b74e3c129fe87edfce58 336 SMART SM00279 222 255 1.0E-13 T 31-10-2018 IPR008918 Helix-hairpin-helix motif, class 2 GO:0003677|GO:0003824 AF_0264 a32035d6bb63b74e3c129fe87edfce58 336 SUPERFAMILY SSF47807 220 336 8.82E-30 T 31-10-2018 IPR036279 5'-3' exonuclease, C-terminal domain superfamily AF_0264 a32035d6bb63b74e3c129fe87edfce58 336 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 159 179 1.1E-34 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 AF_0264 a32035d6bb63b74e3c129fe87edfce58 336 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 75 94 1.1E-34 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 AF_0264 a32035d6bb63b74e3c129fe87edfce58 336 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 138 155 1.1E-34 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 AF_0264 a32035d6bb63b74e3c129fe87edfce58 336 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 21 35 1.1E-34 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 AF_0264 a32035d6bb63b74e3c129fe87edfce58 336 PRINTS PR00853 Xeroderma pigmentosum group G/yeast RAD superfamily signature 225 240 1.1E-34 T 31-10-2018 IPR006084 XPG/Rad2 endonuclease GO:0004518|GO:0006281 AF_0264 a32035d6bb63b74e3c129fe87edfce58 336 Pfam PF00752 XPG N-terminal domain 13 101 4.1E-21 T 31-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 AF_0264 a32035d6bb63b74e3c129fe87edfce58 336 Hamap MF_00614 Flap endonuclease 1 [fen]. 1 336 136.65 T 31-10-2018 IPR023426 Flap endonuclease 1 GO:0016788 Reactome: R-HSA-110362|Reactome: R-HSA-162594|Reactome: R-HSA-174437|Reactome: R-HSA-5651801|Reactome: R-HSA-5685939|Reactome: R-HSA-69166 AF_0264 a32035d6bb63b74e3c129fe87edfce58 336 SMART SM00484 139 220 4.2E-36 T 31-10-2018 IPR006086 XPG-I domain GO:0004518 AF_0264 a32035d6bb63b74e3c129fe87edfce58 336 SMART SM00475 22 300 0.0068 T 31-10-2018 IPR002421 5'-3' exonuclease, N-terminal GO:0003677 AF_0264 a32035d6bb63b74e3c129fe87edfce58 336 Pfam PF00867 XPG I-region 140 235 2.1E-27 T 31-10-2018 IPR006086 XPG-I domain GO:0004518 AF_0264 a32035d6bb63b74e3c129fe87edfce58 336 ProSitePatterns PS00841 XPG protein signature 1. 73 87 - T 31-10-2018 IPR019974 XPG conserved site GO:0016788 AF_0264 a32035d6bb63b74e3c129fe87edfce58 336 SMART SM00485 1 101 4.5E-46 T 31-10-2018 IPR006085 XPG N-terminal GO:0004518|GO:0006281 AF_0264 a32035d6bb63b74e3c129fe87edfce58 336 Gene3D G3DSA:3.40.50.1010 1 219 1.8E-84 T 31-10-2018 AF_1472 0ac9a6fdb391711c4a89d76d2155f463 494 Pfam PF13185 GAF domain 327 406 2.5E-8 T 31-10-2018 IPR003018 GAF domain GO:0005515 AF_1472 0ac9a6fdb391711c4a89d76d2155f463 494 Gene3D G3DSA:3.30.450.40 265 416 2.1E-11 T 31-10-2018 IPR029016 GAF-like domain superfamily AF_1472 0ac9a6fdb391711c4a89d76d2155f463 494 SUPERFAMILY SSF55781 254 407 1.9E-14 T 31-10-2018 AF_1472 0ac9a6fdb391711c4a89d76d2155f463 494 SUPERFAMILY SSF55785 134 259 8.2E-28 T 31-10-2018 IPR035965 PAS domain superfamily AF_1472 0ac9a6fdb391711c4a89d76d2155f463 494 SUPERFAMILY SSF52172 8 162 8.4E-27 T 31-10-2018 IPR011006 CheY-like superfamily AF_1472 0ac9a6fdb391711c4a89d76d2155f463 494 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 143 268 1.7E-35 T 31-10-2018 IPR000014 PAS domain AF_1472 0ac9a6fdb391711c4a89d76d2155f463 494 Pfam PF00989 PAS fold 148 258 1.2E-13 T 31-10-2018 IPR013767 PAS fold GO:0006355 AF_1472 0ac9a6fdb391711c4a89d76d2155f463 494 SMART SM00388 424 482 9.8E-7 T 31-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AF_1472 0ac9a6fdb391711c4a89d76d2155f463 494 SMART SM00448 8 122 3.1E-18 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_1472 0ac9a6fdb391711c4a89d76d2155f463 494 SMART SM00086 220 261 4.6E-7 T 31-10-2018 IPR001610 PAC motif AF_1472 0ac9a6fdb391711c4a89d76d2155f463 494 Gene3D G3DSA:3.40.50.2300 6 138 2.7E-22 T 31-10-2018 AF_1472 0ac9a6fdb391711c4a89d76d2155f463 494 Pfam PF00072 Response regulator receiver domain 10 112 3.8E-16 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_1472 0ac9a6fdb391711c4a89d76d2155f463 494 SMART SM00091 147 213 6.8E-12 T 31-10-2018 IPR000014 PAS domain AF_1472 0ac9a6fdb391711c4a89d76d2155f463 494 Gene3D G3DSA:3.30.450.20 139 264 1.2E-27 T 31-10-2018 AF_1919 f4daf7127f7e071b801997b8328a0b36 229 SUPERFAMILY SSF54821 85 185 1.7E-25 T 31-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1919 f4daf7127f7e071b801997b8328a0b36 229 Pfam PF00189 Ribosomal protein S3, C-terminal domain 98 181 3.8E-23 T 31-10-2018 IPR001351 Ribosomal protein S3, C-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1919 f4daf7127f7e071b801997b8328a0b36 229 Gene3D G3DSA:3.30.300.20 1 85 8.2E-23 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta AF_1919 f4daf7127f7e071b801997b8328a0b36 229 Pfam PF07650 KH domain 17 88 1.3E-12 T 31-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1919 f4daf7127f7e071b801997b8328a0b36 229 Hamap MF_01309_A 30S ribosomal protein S3 [rpsC]. 2 196 41.638 T 31-10-2018 IPR027488 Ribosomal protein S3, archaeal GO:0003735|GO:0006412|GO:0015935 AF_1919 f4daf7127f7e071b801997b8328a0b36 229 SMART SM00322 38 103 1.7E-6 T 31-10-2018 IPR004087 K Homology domain GO:0003676 AF_1919 f4daf7127f7e071b801997b8328a0b36 229 Gene3D G3DSA:3.30.1140.32 88 225 6.1E-36 T 31-10-2018 IPR036419 Ribosomal protein S3, C-terminal domain superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1919 f4daf7127f7e071b801997b8328a0b36 229 SUPERFAMILY SSF54814 6 94 1.31E-20 T 31-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AF_1919 f4daf7127f7e071b801997b8328a0b36 229 TIGRFAM TIGR01008 uS3_euk_arch: ribosomal protein uS3 3 196 7.2E-91 T 31-10-2018 IPR005703 Ribosomal protein S3, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1463 e4c3a8bb7aa235e29b651229c8f0865b 575 Pfam PF00890 FAD binding domain 56 151 4.2E-10 T 31-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_1463 e4c3a8bb7aa235e29b651229c8f0865b 575 SUPERFAMILY SSF51905 43 424 8.65E-44 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1463 e4c3a8bb7aa235e29b651229c8f0865b 575 Pfam PF02910 Fumarate reductase flavoprotein C-term 499 565 2.6E-10 T 31-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_1463 e4c3a8bb7aa235e29b651229c8f0865b 575 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 377 384 1.3E-7 T 31-10-2018 AF_1463 e4c3a8bb7aa235e29b651229c8f0865b 575 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 56 78 1.3E-7 T 31-10-2018 AF_1463 e4c3a8bb7aa235e29b651229c8f0865b 575 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 209 218 1.3E-7 T 31-10-2018 AF_1463 e4c3a8bb7aa235e29b651229c8f0865b 575 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 206 224 2.0E-12 T 31-10-2018 AF_1463 e4c3a8bb7aa235e29b651229c8f0865b 575 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 362 384 2.0E-12 T 31-10-2018 AF_1463 e4c3a8bb7aa235e29b651229c8f0865b 575 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 57 76 2.0E-12 T 31-10-2018 AF_1463 e4c3a8bb7aa235e29b651229c8f0865b 575 SUPERFAMILY SSF46977 441 565 5.63E-30 T 31-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_1463 e4c3a8bb7aa235e29b651229c8f0865b 575 Gene3D G3DSA:1.20.58.100 426 539 5.5E-26 T 31-10-2018 AF_1463 e4c3a8bb7aa235e29b651229c8f0865b 575 Gene3D G3DSA:3.50.50.60 44 265 3.6E-38 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1463 e4c3a8bb7aa235e29b651229c8f0865b 575 Gene3D G3DSA:3.50.50.60 351 425 2.9E-6 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1463 e4c3a8bb7aa235e29b651229c8f0865b 575 PIRSF PIRSF000171 45 154 6.3E-10 T 31-10-2018 AF_1463 e4c3a8bb7aa235e29b651229c8f0865b 575 PIRSF PIRSF000171 157 255 7.6E-8 T 31-10-2018 AF_1463 e4c3a8bb7aa235e29b651229c8f0865b 575 PIRSF PIRSF000171 342 568 4.0E-32 T 31-10-2018 AF_0965 0ad92593ef80e7f9f8e89bb15c6cbf4f 154 SUPERFAMILY SSF50249 9 140 5.65E-29 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0965 0ad92593ef80e7f9f8e89bb15c6cbf4f 154 Gene3D G3DSA:1.10.12.20 1 74 1.5E-22 T 31-10-2018 AF_0965 0ad92593ef80e7f9f8e89bb15c6cbf4f 154 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 39 68 4.3E-9 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AF_0965 0ad92593ef80e7f9f8e89bb15c6cbf4f 154 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 72 135 1.3E-9 T 31-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AF_2004 50e16d996c4efa6c4fb8d3448ee6f047 367 TIGRFAM TIGR03812 tyr_de_CO2_Arch: tyrosine decarboxylase MnfA 2 364 1.2E-163 T 31-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AF_2004 50e16d996c4efa6c4fb8d3448ee6f047 367 ProSitePatterns PS00392 DDC / GAD / HDC / TyrDC pyridoxal-phosphate attachment site. 209 230 - T 31-10-2018 IPR021115 Pyridoxal-phosphate binding site GO:0016831 AF_2004 50e16d996c4efa6c4fb8d3448ee6f047 367 SUPERFAMILY SSF53383 15 366 4.03E-99 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AF_2004 50e16d996c4efa6c4fb8d3448ee6f047 367 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 54 315 9.5E-32 T 31-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 AF_2004 50e16d996c4efa6c4fb8d3448ee6f047 367 Hamap MF_01610 Probable L-tyrosine/L-aspartate decarboxylase [mfnA]. 5 365 57.94 T 31-10-2018 IPR020931 Decarboxylase MfnA, archaea GO:0016831 KEGG: 00410+4.1.1.11|KEGG: 00770+4.1.1.11|MetaCyc: PWY-5155 AF_2004 50e16d996c4efa6c4fb8d3448ee6f047 367 Gene3D G3DSA:3.40.640.10 29 273 4.0E-124 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AF_2004 50e16d996c4efa6c4fb8d3448ee6f047 367 Gene3D G3DSA:3.90.1150.10 2 358 4.0E-124 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AF_0905 73e90eb29ecd91f96a1aa548935da8d3 124 Hamap MF_01095 UPF0292 protein . 1 121 33.003 T 31-10-2018 IPR022972 Uncharacterised protein family UPF0292 AF_0905 73e90eb29ecd91f96a1aa548935da8d3 124 Gene3D G3DSA:3.40.1360.10 2 117 9.4E-20 T 31-10-2018 AF_0905 73e90eb29ecd91f96a1aa548935da8d3 124 Pfam PF01751 Toprim domain 23 97 1.2E-5 T 31-10-2018 IPR006171 TOPRIM domain AF_0905 73e90eb29ecd91f96a1aa548935da8d3 124 SUPERFAMILY SSF110455 22 87 1.28E-9 T 31-10-2018 AF_0905 73e90eb29ecd91f96a1aa548935da8d3 124 SMART SM00493 21 88 7.4E-11 T 31-10-2018 IPR006171 TOPRIM domain AF_1026 8536862633da461b85b57e3acf2faad4 397 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 118 4.5E-37 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AF_1026 8536862633da461b85b57e3acf2faad4 397 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 231 381 7.9E-51 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AF_1026 8536862633da461b85b57e3acf2faad4 397 Gene3D G3DSA:1.20.140.10 236 388 7.7E-49 T 31-10-2018 AF_1026 8536862633da461b85b57e3acf2faad4 397 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 339 358 - T 31-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AF_1026 8536862633da461b85b57e3acf2faad4 397 Gene3D G3DSA:1.10.540.10 2 120 2.7E-42 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AF_1026 8536862633da461b85b57e3acf2faad4 397 SUPERFAMILY SSF56645 4 242 1.57E-88 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AF_1026 8536862633da461b85b57e3acf2faad4 397 PIRSF PIRSF016578 4 389 8.7E-19 T 31-10-2018 AF_1026 8536862633da461b85b57e3acf2faad4 397 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 219 3.4E-31 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AF_1026 8536862633da461b85b57e3acf2faad4 397 Gene3D G3DSA:2.40.110.10 121 235 3.3E-48 T 31-10-2018 AF_1026 8536862633da461b85b57e3acf2faad4 397 SUPERFAMILY SSF47203 229 384 2.58E-53 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AF_1951 2a9097a212706197391fef875dd5b7c1 606 Pfam PF00437 Type II/IV secretion system protein 230 389 2.4E-8 T 31-10-2018 IPR001482 Type II/IV secretion system protein AF_1951 2a9097a212706197391fef875dd5b7c1 606 SUPERFAMILY SSF88723 18 149 1.57E-18 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_1951 2a9097a212706197391fef875dd5b7c1 606 Gene3D G3DSA:3.30.1370.10 491 555 8.4E-7 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AF_1951 2a9097a212706197391fef875dd5b7c1 606 SMART SM00382 275 443 1.4E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1951 2a9097a212706197391fef875dd5b7c1 606 SMART SM00670 18 131 7.9E-27 T 31-10-2018 IPR002716 PIN domain AF_1951 2a9097a212706197391fef875dd5b7c1 606 SMART SM00322 489 556 5.8E-5 T 31-10-2018 IPR004087 K Homology domain GO:0003676 AF_1951 2a9097a212706197391fef875dd5b7c1 606 Gene3D G3DSA:3.40.50.1010 16 143 3.2E-34 T 31-10-2018 AF_1951 2a9097a212706197391fef875dd5b7c1 606 SUPERFAMILY SSF54791 493 530 4.67E-7 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AF_1951 2a9097a212706197391fef875dd5b7c1 606 Pfam PF13638 PIN domain 20 140 8.2E-5 T 31-10-2018 IPR002716 PIN domain AF_1951 2a9097a212706197391fef875dd5b7c1 606 SUPERFAMILY SSF52540 148 456 1.28E-32 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1951 2a9097a212706197391fef875dd5b7c1 606 Gene3D G3DSA:3.40.50.300 257 476 2.4E-18 T 31-10-2018 AF_1951 2a9097a212706197391fef875dd5b7c1 606 Pfam PF00013 KH domain 494 546 3.0E-8 T 31-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 AF_1686 9e830f9accad59043d98fba6e75eb950 100 Pfam PF01909 Nucleotidyltransferase domain 7 98 4.1E-16 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AF_1686 9e830f9accad59043d98fba6e75eb950 100 Gene3D G3DSA:3.30.460.10 1 98 2.7E-21 T 31-10-2018 AF_1686 9e830f9accad59043d98fba6e75eb950 100 SUPERFAMILY SSF81301 1 96 2.97E-22 T 31-10-2018 AF_1388 5422993a7d4424946b9c1ff63a67500e 648 Pfam PF13087 AAA domain 416 611 4.0E-59 T 31-10-2018 AF_1388 5422993a7d4424946b9c1ff63a67500e 648 Gene3D G3DSA:2.40.30.270 27 121 2.0E-88 T 31-10-2018 AF_1388 5422993a7d4424946b9c1ff63a67500e 648 Pfam PF13086 AAA domain 169 412 9.9E-54 T 31-10-2018 AF_1388 5422993a7d4424946b9c1ff63a67500e 648 Gene3D G3DSA:3.40.50.300 439 640 4.6E-62 T 31-10-2018 AF_1388 5422993a7d4424946b9c1ff63a67500e 648 TIGRFAM TIGR00376 TIGR00376: putative DNA helicase 13 639 5.5E-296 T 31-10-2018 IPR004483 Helicase SMUBP-2/Hcs1-like GO:0003677|GO:0005524 AF_1388 5422993a7d4424946b9c1ff63a67500e 648 SUPERFAMILY SSF52540 162 617 4.58E-63 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1388 5422993a7d4424946b9c1ff63a67500e 648 Gene3D G3DSA:3.40.50.300 10 424 2.0E-88 T 31-10-2018 AF_1367 b16ce65c0ec797b573284a1a0619c95e 110 PIRSF PIRSF004761 1 110 1.3E-30 T 31-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 AF_1367 b16ce65c0ec797b573284a1a0619c95e 110 Pfam PF01155 Hydrogenase/urease nickel incorporation, metallochaperone, hypA 2 107 4.8E-26 T 31-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 AF_1367 b16ce65c0ec797b573284a1a0619c95e 110 ProSitePatterns PS01249 Hydrogenases expression/synthesis hypA family signature. 34 76 - T 31-10-2018 IPR020538 Hydrogenase nickel incorporation protein HypA/HybF, conserved site AF_1367 b16ce65c0ec797b573284a1a0619c95e 110 Gene3D G3DSA:2.20.28.10 69 98 1.4E-26 T 31-10-2018 AF_1367 b16ce65c0ec797b573284a1a0619c95e 110 Hamap MF_00213 Hydrogenase maturation factor HypA [hypA]. 1 109 20.679 T 31-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 AF_1367 b16ce65c0ec797b573284a1a0619c95e 110 Gene3D G3DSA:3.30.2320.50 2 105 1.4E-26 T 31-10-2018 AF_1367 b16ce65c0ec797b573284a1a0619c95e 110 TIGRFAM TIGR00100 hypA: hydrogenase nickel insertion protein HypA 1 109 1.6E-35 T 31-10-2018 IPR000688 Hydrogenase maturation factor HypA/HybF GO:0016151|GO:0051604 AF_0164 a14e266a71ce7509b71ffe944c780c55 436 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 105 253 3.6E-30 T 31-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AF_0164 a14e266a71ce7509b71ffe944c780c55 436 SUPERFAMILY SSF56014 103 261 2.75E-28 T 31-10-2018 AF_0164 a14e266a71ce7509b71ffe944c780c55 436 Gene3D G3DSA:3.30.413.10 103 264 6.8E-74 T 31-10-2018 AF_0164 a14e266a71ce7509b71ffe944c780c55 436 SUPERFAMILY SSF56014 340 410 2.09E-9 T 31-10-2018 AF_0164 a14e266a71ce7509b71ffe944c780c55 436 ProSitePatterns PS00365 Nitrite and sulfite reductases iron-sulfur/siroheme-binding site. 374 390 - T 31-10-2018 IPR006066 Nitrite/sulphite reductase iron-sulphur/sirohaem-binding site GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AF_0164 a14e266a71ce7509b71ffe944c780c55 436 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 28 87 8.9E-20 T 31-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AF_0164 a14e266a71ce7509b71ffe944c780c55 436 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 272 332 2.2E-13 T 31-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AF_0164 a14e266a71ce7509b71ffe944c780c55 436 SUPERFAMILY SSF55124 10 92 1.74E-21 T 31-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AF_0164 a14e266a71ce7509b71ffe944c780c55 436 SUPERFAMILY SSF55124 272 331 2.43E-10 T 31-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AF_0164 a14e266a71ce7509b71ffe944c780c55 436 Gene3D G3DSA:3.30.413.10 324 430 1.3E-5 T 31-10-2018 AF_0164 a14e266a71ce7509b71ffe944c780c55 436 Gene3D G3DSA:3.90.480.10 31 322 6.8E-74 T 31-10-2018 AF_2170 bfe0061a99630cecf1711d308b71ff79 324 SUPERFAMILY SSF117281 84 305 5.89E-26 T 31-10-2018 IPR015915 Kelch-type beta propeller GO:0005515 AF_2170 bfe0061a99630cecf1711d308b71ff79 324 Pfam PF13854 Kelch motif 264 297 6.7E-6 T 31-10-2018 AF_2170 bfe0061a99630cecf1711d308b71ff79 324 Gene3D G3DSA:2.120.10.80 68 317 3.5E-21 T 31-10-2018 IPR015915 Kelch-type beta propeller GO:0005515 AF_2176 fd83ff754f41023a15a6e79cadd18388 291 Pfam PF01040 UbiA prenyltransferase family 19 268 2.8E-46 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AF_2176 fd83ff754f41023a15a6e79cadd18388 291 TIGRFAM TIGR01475 ubiA_other: putative 4-hydroxybenzoate polyprenyltransferase 3 287 8.4E-116 T 31-10-2018 IPR006371 4-hydroxybenzoate polyprenyltransferase-related AF_2176 fd83ff754f41023a15a6e79cadd18388 291 Gene3D G3DSA:1.10.357.140 10 164 1.4E-52 T 31-10-2018 AF_2176 fd83ff754f41023a15a6e79cadd18388 291 Gene3D G3DSA:1.20.120.1780 165 291 8.9E-31 T 31-10-2018 AF_2322 c1e571b38b69cccbc2cf8668ef7819aa 219 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 7 209 3.8E-78 T 31-10-2018 AF_2322 c1e571b38b69cccbc2cf8668ef7819aa 219 SUPERFAMILY SSF53335 6 208 8.36E-50 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_2322 c1e571b38b69cccbc2cf8668ef7819aa 219 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 4 210 2.8E-79 T 31-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 AF_2322 c1e571b38b69cccbc2cf8668ef7819aa 219 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 134 149 - T 31-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 AF_2322 c1e571b38b69cccbc2cf8668ef7819aa 219 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 4 213 42.978 T 31-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 AF_2322 c1e571b38b69cccbc2cf8668ef7819aa 219 Gene3D G3DSA:3.40.50.150 1 219 9.0E-89 T 31-10-2018 AF_2037 8bcc1f95a2788b4593e407ec68e65060 313 Gene3D G3DSA:1.20.120.420 1 104 2.4E-26 T 31-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AF_2037 8bcc1f95a2788b4593e407ec68e65060 313 TIGRFAM TIGR00511 ribulose_e2b2: ribose-1,5-bisphosphate isomerase, e2b2 family 3 296 4.4E-148 T 31-10-2018 IPR005250 Ribose-1,5-bisphosphate isomerase, e2b2 family MetaCyc: PWY-5532 AF_2037 8bcc1f95a2788b4593e407ec68e65060 313 SUPERFAMILY SSF100950 3 296 4.81E-98 T 31-10-2018 IPR037171 NagB/RpiA transferase-like AF_2037 8bcc1f95a2788b4593e407ec68e65060 313 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 1 284 8.3E-115 T 31-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AF_2037 8bcc1f95a2788b4593e407ec68e65060 313 Pfam PF01008 Initiation factor 2 subunit family 15 284 5.4E-99 T 31-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 AF_2037 8bcc1f95a2788b4593e407ec68e65060 313 Gene3D G3DSA:3.40.50.10470 105 287 3.7E-69 T 31-10-2018 AF_0273 c714804d13ab1a4a9bc480ed1105b976 534 Gene3D G3DSA:3.10.20.440 12 108 9.0E-32 T 31-10-2018 AF_0273 c714804d13ab1a4a9bc480ed1105b976 534 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 172 191 7.2E-20 T 31-10-2018 AF_0273 c714804d13ab1a4a9bc480ed1105b976 534 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 278 296 7.2E-20 T 31-10-2018 AF_0273 c714804d13ab1a4a9bc480ed1105b976 534 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 322 340 7.2E-20 T 31-10-2018 AF_0273 c714804d13ab1a4a9bc480ed1105b976 534 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 412 428 7.2E-20 T 31-10-2018 AF_0273 c714804d13ab1a4a9bc480ed1105b976 534 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 444 466 7.2E-20 T 31-10-2018 AF_0273 c714804d13ab1a4a9bc480ed1105b976 534 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 281 290 2.3E-19 T 31-10-2018 AF_0273 c714804d13ab1a4a9bc480ed1105b976 534 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 459 466 2.3E-19 T 31-10-2018 AF_0273 c714804d13ab1a4a9bc480ed1105b976 534 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 322 347 2.3E-19 T 31-10-2018 AF_0273 c714804d13ab1a4a9bc480ed1105b976 534 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 413 427 2.3E-19 T 31-10-2018 AF_0273 c714804d13ab1a4a9bc480ed1105b976 534 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 171 193 2.3E-19 T 31-10-2018 AF_0273 c714804d13ab1a4a9bc480ed1105b976 534 Pfam PF13510 2Fe-2S iron-sulfur cluster binding domain 21 101 1.1E-31 T 31-10-2018 AF_0273 c714804d13ab1a4a9bc480ed1105b976 534 SUPERFAMILY SSF51905 170 489 8.85E-37 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0273 c714804d13ab1a4a9bc480ed1105b976 534 SUPERFAMILY SSF54292 23 106 1.14E-24 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AF_0273 c714804d13ab1a4a9bc480ed1105b976 534 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 66 74 - T 31-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AF_0273 c714804d13ab1a4a9bc480ed1105b976 534 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 171 478 1.6E-46 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AF_0273 c714804d13ab1a4a9bc480ed1105b976 534 Gene3D G3DSA:3.50.50.60 164 315 2.2E-32 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0273 c714804d13ab1a4a9bc480ed1105b976 534 Gene3D G3DSA:3.50.50.60 323 518 4.2E-19 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1216 c630ed7f50c482a60df101e040aa6943 493 Gene3D G3DSA:1.10.10.770 309 402 1.3E-14 T 31-10-2018 AF_1216 c630ed7f50c482a60df101e040aa6943 493 Gene3D G3DSA:3.40.50.620 3 261 3.1E-95 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_1216 c630ed7f50c482a60df101e040aa6943 493 Gene3D G3DSA:1.10.10.860 262 308 1.4E-6 T 31-10-2018 AF_1216 c630ed7f50c482a60df101e040aa6943 493 TIGRFAM TIGR00467 lysS_arch: lysine--tRNA ligase 1 492 2.1E-255 T 31-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 AF_1216 c630ed7f50c482a60df101e040aa6943 493 Hamap MF_00177 Lysine--tRNA ligase [lysS]. 1 493 37.905 T 31-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 AF_1216 c630ed7f50c482a60df101e040aa6943 493 Gene3D G3DSA:2.30.30.300 162 205 3.1E-95 T 31-10-2018 IPR023386 Lysine-tRNA ligase, insertion domain superfamily GO:0004824 KEGG: 00970+6.1.1.6 AF_1216 c630ed7f50c482a60df101e040aa6943 493 Pfam PF01921 tRNA synthetases class I (K) 1 324 1.3E-126 T 31-10-2018 IPR002904 Lysine-tRNA ligase GO:0000166|GO:0004824|GO:0005524|GO:0005737|GO:0006430 KEGG: 00970+6.1.1.6 AF_1216 c630ed7f50c482a60df101e040aa6943 493 Gene3D G3DSA:1.10.10.350 403 491 5.3E-24 T 31-10-2018 IPR020751 Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AF_1216 c630ed7f50c482a60df101e040aa6943 493 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 26 35 - T 31-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_1216 c630ed7f50c482a60df101e040aa6943 493 SUPERFAMILY SSF48163 331 493 1.03E-38 T 31-10-2018 IPR008925 Aminoacyl-tRNA synthetase, class I, anticodon-binding GO:0000049 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-379726 AF_1216 c630ed7f50c482a60df101e040aa6943 493 SUPERFAMILY SSF52374 3 309 7.51E-61 T 31-10-2018 AF_1603 2cfde8303ddc5a0a810d6dd3da0a12a7 411 TIGRFAM TIGR01820 TrpE-arch: anthranilate synthase component I 9 410 1.3E-156 T 31-10-2018 IPR010116 Anthranilate synthase component I, archaeal type GO:0000162|GO:0004049 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AF_1603 2cfde8303ddc5a0a810d6dd3da0a12a7 411 Pfam PF04715 Anthranilate synthase component I, N terminal region 7 119 2.1E-12 T 31-10-2018 IPR006805 Anthranilate synthase component I, N-terminal GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AF_1603 2cfde8303ddc5a0a810d6dd3da0a12a7 411 Pfam PF00425 chorismate binding enzyme 152 401 9.2E-86 T 31-10-2018 IPR015890 Chorismate-utilising enzyme, C-terminal AF_1603 2cfde8303ddc5a0a810d6dd3da0a12a7 411 Gene3D G3DSA:3.60.120.10 2 411 2.8E-124 T 31-10-2018 IPR005801 ADC synthase GO:0009058 AF_1603 2cfde8303ddc5a0a810d6dd3da0a12a7 411 SUPERFAMILY SSF56322 11 410 6.41E-114 T 31-10-2018 IPR005801 ADC synthase GO:0009058 AF_1603 2cfde8303ddc5a0a810d6dd3da0a12a7 411 PRINTS PR00095 Anthranilate synthase component I signature 345 359 1.7E-17 T 31-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AF_1603 2cfde8303ddc5a0a810d6dd3da0a12a7 411 PRINTS PR00095 Anthranilate synthase component I signature 265 278 1.7E-17 T 31-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AF_1603 2cfde8303ddc5a0a810d6dd3da0a12a7 411 PRINTS PR00095 Anthranilate synthase component I signature 251 264 1.7E-17 T 31-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AF_1603 2cfde8303ddc5a0a810d6dd3da0a12a7 411 PRINTS PR00095 Anthranilate synthase component I signature 359 373 1.7E-17 T 31-10-2018 IPR019999 Anthranilate synthase component I-like GO:0009058 KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AF_1708 8f409d8fdb931ae2aed6a21cb8c1c41e 957 Gene3D G3DSA:3.40.50.300 418 666 1.2E-39 T 31-10-2018 AF_1708 8f409d8fdb931ae2aed6a21cb8c1c41e 957 SUPERFAMILY SSF52540 190 451 2.59E-25 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1708 8f409d8fdb931ae2aed6a21cb8c1c41e 957 Pfam PF04851 Type III restriction enzyme, res subunit 222 394 1.6E-19 T 31-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AF_1708 8f409d8fdb931ae2aed6a21cb8c1c41e 957 TIGRFAM TIGR00348 hsdR: type I site-specific deoxyribonuclease, HsdR family 6 658 1.8E-246 T 31-10-2018 IPR004473 Restriction endonuclease, type I, HsdR GO:0003677|GO:0005524|GO:0009035|GO:0009307 AF_1708 8f409d8fdb931ae2aed6a21cb8c1c41e 957 Gene3D G3DSA:3.90.1570.50 76 170 2.4E-13 T 31-10-2018 AF_1708 8f409d8fdb931ae2aed6a21cb8c1c41e 957 SMART SM00487 218 430 5.1E-12 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AF_1708 8f409d8fdb931ae2aed6a21cb8c1c41e 957 Gene3D G3DSA:3.40.50.300 221 417 3.8E-43 T 31-10-2018 AF_1708 8f409d8fdb931ae2aed6a21cb8c1c41e 957 Pfam PF04313 Type I restriction enzyme R protein N terminus (HSDR_N) 4 179 1.4E-31 T 31-10-2018 IPR007409 Restriction endonuclease, type I, HsdR, N-terminal GO:0003677|GO:0004519|GO:0006304 AF_1708 8f409d8fdb931ae2aed6a21cb8c1c41e 957 SUPERFAMILY SSF52540 249 623 8.69E-5 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2035 ba9abde44d68c0b5ef8be7766faa5cf0 453 Pfam PF02403 Seryl-tRNA synthetase N-terminal domain 5 106 2.3E-23 T 31-10-2018 IPR015866 Serine-tRNA synthetase, type1, N-terminal KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281|Reactome: R-HSA-2408557|Reactome: R-HSA-379716 AF_2035 ba9abde44d68c0b5ef8be7766faa5cf0 453 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 237 418 1.0E-38 T 31-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_2035 ba9abde44d68c0b5ef8be7766faa5cf0 453 SUPERFAMILY SSF46589 6 112 7.85E-27 T 31-10-2018 IPR010978 Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm GO:0000166 AF_2035 ba9abde44d68c0b5ef8be7766faa5cf0 453 Hamap MF_00176 Serine--tRNA ligase [serS]. 2 441 40.167 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AF_2035 ba9abde44d68c0b5ef8be7766faa5cf0 453 Gene3D G3DSA:3.30.930.10 105 446 1.3E-126 T 31-10-2018 AF_2035 ba9abde44d68c0b5ef8be7766faa5cf0 453 PRINTS PR00981 Seryl-tRNA synthetase signature 369 385 2.4E-34 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AF_2035 ba9abde44d68c0b5ef8be7766faa5cf0 453 PRINTS PR00981 Seryl-tRNA synthetase signature 294 307 2.4E-34 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AF_2035 ba9abde44d68c0b5ef8be7766faa5cf0 453 PRINTS PR00981 Seryl-tRNA synthetase signature 351 367 2.4E-34 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AF_2035 ba9abde44d68c0b5ef8be7766faa5cf0 453 PRINTS PR00981 Seryl-tRNA synthetase signature 334 347 2.4E-34 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AF_2035 ba9abde44d68c0b5ef8be7766faa5cf0 453 PRINTS PR00981 Seryl-tRNA synthetase signature 282 294 2.4E-34 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AF_2035 ba9abde44d68c0b5ef8be7766faa5cf0 453 Gene3D G3DSA:1.10.287.40 5 104 4.7E-24 T 31-10-2018 AF_2035 ba9abde44d68c0b5ef8be7766faa5cf0 453 TIGRFAM TIGR00414 serS: serine--tRNA ligase 1 436 5.9E-177 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AF_2035 ba9abde44d68c0b5ef8be7766faa5cf0 453 SUPERFAMILY SSF55681 150 436 2.25E-84 T 31-10-2018 AF_2035 ba9abde44d68c0b5ef8be7766faa5cf0 453 PIRSF PIRSF001529 4 445 8.6E-145 T 31-10-2018 IPR002317 Serine-tRNA ligase, type1 GO:0000166|GO:0004828|GO:0005524|GO:0005737|GO:0006434 KEGG: 00970+6.1.1.11|MetaCyc: PWY-6281 AF_1726 dcb450951f66e4c38b1878caef144be7 286 TIGRFAM TIGR02772 Ku_bact: Ku protein 34 285 1.4E-99 T 31-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type AF_1726 dcb450951f66e4c38b1878caef144be7 286 Gene3D G3DSA:2.40.290.10 35 208 4.8E-24 T 31-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily AF_1726 dcb450951f66e4c38b1878caef144be7 286 SUPERFAMILY SSF100939 34 285 6.67E-53 T 31-10-2018 IPR016194 SPOC-like, C-terminal domain superfamily AF_1726 dcb450951f66e4c38b1878caef144be7 286 Pfam PF02735 Ku70/Ku80 beta-barrel domain 44 223 1.1E-39 T 31-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 AF_1726 dcb450951f66e4c38b1878caef144be7 286 PIRSF PIRSF006493 32 286 1.4E-108 T 31-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type AF_1726 dcb450951f66e4c38b1878caef144be7 286 SMART SM00559 85 213 6.3E-51 T 31-10-2018 IPR006164 Ku70/Ku80 beta-barrel domain GO:0003677|GO:0006303 Reactome: R-HSA-164843|Reactome: R-HSA-1834949|Reactome: R-HSA-3270619|Reactome: R-HSA-5693571|Reactome: R-HSA-6798695 AF_1726 dcb450951f66e4c38b1878caef144be7 286 Hamap MF_01875 Non-homologous end joining protein Ku [ku]. 34 283 32.928 T 31-10-2018 IPR009187 Non-homologous end joining protein Ku, prokaryotic type AF_2420 5992456f8d79938bf34098750ace89d7 547 Gene3D G3DSA:3.30.450.20 191 313 1.8E-31 T 31-10-2018 AF_2420 5992456f8d79938bf34098750ace89d7 547 Gene3D G3DSA:3.30.450.20 69 190 5.2E-18 T 31-10-2018 AF_2420 5992456f8d79938bf34098750ace89d7 547 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 70 189 2.2E-22 T 31-10-2018 IPR000014 PAS domain AF_2420 5992456f8d79938bf34098750ace89d7 547 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 186 310 1.0E-37 T 31-10-2018 IPR000014 PAS domain AF_2420 5992456f8d79938bf34098750ace89d7 547 SMART SM00388 474 530 0.0046 T 31-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AF_2420 5992456f8d79938bf34098750ace89d7 547 Pfam PF00989 PAS fold 190 300 3.7E-16 T 31-10-2018 IPR013767 PAS fold GO:0006355 AF_2420 5992456f8d79938bf34098750ace89d7 547 Pfam PF00989 PAS fold 73 179 6.1E-10 T 31-10-2018 IPR013767 PAS fold GO:0006355 AF_2420 5992456f8d79938bf34098750ace89d7 547 Gene3D G3DSA:3.30.450.40 314 462 9.5E-16 T 31-10-2018 IPR029016 GAF-like domain superfamily AF_2420 5992456f8d79938bf34098750ace89d7 547 SUPERFAMILY SSF55785 186 301 4.54E-26 T 31-10-2018 IPR035965 PAS domain superfamily AF_2420 5992456f8d79938bf34098750ace89d7 547 Pfam PF13185 GAF domain 331 457 4.8E-14 T 31-10-2018 IPR003018 GAF domain GO:0005515 AF_2420 5992456f8d79938bf34098750ace89d7 547 SUPERFAMILY SSF55781 298 457 3.49E-17 T 31-10-2018 AF_2420 5992456f8d79938bf34098750ace89d7 547 SMART SM00065 332 466 0.0053 T 31-10-2018 IPR003018 GAF domain GO:0005515 AF_2420 5992456f8d79938bf34098750ace89d7 547 SUPERFAMILY SSF55785 75 183 3.91E-21 T 31-10-2018 IPR035965 PAS domain superfamily AF_2420 5992456f8d79938bf34098750ace89d7 547 SMART SM00091 72 137 1.0E-10 T 31-10-2018 IPR000014 PAS domain AF_2420 5992456f8d79938bf34098750ace89d7 547 SMART SM00091 189 255 2.4E-12 T 31-10-2018 IPR000014 PAS domain AF_1300 3908b3684b61ef6b9ba4c7b42c6c6396 303 Pfam PF00005 ABC transporter 24 164 1.6E-24 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_1300 3908b3684b61ef6b9ba4c7b42c6c6396 303 SUPERFAMILY SSF52540 4 229 6.82E-56 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1300 3908b3684b61ef6b9ba4c7b42c6c6396 303 SMART SM00382 33 212 1.8E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1300 3908b3684b61ef6b9ba4c7b42c6c6396 303 Gene3D G3DSA:3.40.50.300 1 241 9.2E-58 T 31-10-2018 AF_0511 c55b7611c724acf4621ea04d09cde383 129 ProSitePatterns PS00578 Ribosomal protein S6e signature. 52 63 - T 31-10-2018 IPR018282 Ribosomal protein S6e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0511 c55b7611c724acf4621ea04d09cde383 129 SMART SM01405 3 125 1.3E-56 T 31-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0511 c55b7611c724acf4621ea04d09cde383 129 Pfam PF01092 Ribosomal protein S6e 3 123 1.2E-38 T 31-10-2018 IPR001377 Ribosomal protein S6e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-166208|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0511 c55b7611c724acf4621ea04d09cde383 129 Hamap MF_00512 30S ribosomal protein S6e [rps6e]. 1 114 18.509 T 31-10-2018 IPR020924 Ribosomal protein S6e, archaeal GO:0003735|GO:0005840|GO:0006412 AF_2242 6aa6f9252ea3987a3651d1fe83150c00 444 Pfam PF00206 Lyase 12 293 4.8E-56 T 31-10-2018 IPR022761 Fumarate lyase, N-terminal AF_2242 6aa6f9252ea3987a3651d1fe83150c00 444 TIGRFAM TIGR00928 purB: adenylosuccinate lyase 6 436 2.4E-181 T 31-10-2018 IPR004769 Adenylosuccinate lyase GO:0004018|GO:0009152 KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AF_2242 6aa6f9252ea3987a3651d1fe83150c00 444 PRINTS PR00145 Argininosuccinate lyase family signature 91 113 3.8E-8 T 31-10-2018 AF_2242 6aa6f9252ea3987a3651d1fe83150c00 444 PRINTS PR00145 Argininosuccinate lyase family signature 132 152 3.8E-8 T 31-10-2018 AF_2242 6aa6f9252ea3987a3651d1fe83150c00 444 PRINTS PR00145 Argininosuccinate lyase family signature 223 247 3.8E-8 T 31-10-2018 AF_2242 6aa6f9252ea3987a3651d1fe83150c00 444 PRINTS PR00145 Argininosuccinate lyase family signature 268 284 3.8E-8 T 31-10-2018 AF_2242 6aa6f9252ea3987a3651d1fe83150c00 444 Gene3D G3DSA:1.20.200.10 97 355 1.1E-91 T 31-10-2018 AF_2242 6aa6f9252ea3987a3651d1fe83150c00 444 SMART SM00998 356 436 7.1E-34 T 31-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AF_2242 6aa6f9252ea3987a3651d1fe83150c00 444 PRINTS PR00149 Fumarate lyase superfamily signature 223 250 2.9E-26 T 31-10-2018 IPR000362 Fumarate lyase family AF_2242 6aa6f9252ea3987a3651d1fe83150c00 444 PRINTS PR00149 Fumarate lyase superfamily signature 92 110 2.9E-26 T 31-10-2018 IPR000362 Fumarate lyase family AF_2242 6aa6f9252ea3987a3651d1fe83150c00 444 PRINTS PR00149 Fumarate lyase superfamily signature 137 155 2.9E-26 T 31-10-2018 IPR000362 Fumarate lyase family AF_2242 6aa6f9252ea3987a3651d1fe83150c00 444 PRINTS PR00149 Fumarate lyase superfamily signature 268 284 2.9E-26 T 31-10-2018 IPR000362 Fumarate lyase family AF_2242 6aa6f9252ea3987a3651d1fe83150c00 444 Gene3D G3DSA:1.10.275.10 1 96 3.5E-35 T 31-10-2018 IPR024083 Fumarase/histidase, N-terminal AF_2242 6aa6f9252ea3987a3651d1fe83150c00 444 ProSitePatterns PS00163 Fumarate lyases signature. 268 277 - T 31-10-2018 IPR020557 Fumarate lyase, conserved site GO:0003824 AF_2242 6aa6f9252ea3987a3651d1fe83150c00 444 Gene3D G3DSA:1.10.40.30 356 436 2.9E-25 T 31-10-2018 AF_2242 6aa6f9252ea3987a3651d1fe83150c00 444 Pfam PF10397 Adenylosuccinate lyase C-terminus 357 435 1.8E-22 T 31-10-2018 IPR019468 Adenylosuccinate lyase C-terminal KEGG: 00230+4.3.2.2|KEGG: 00250+4.3.2.2|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7219|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AF_2242 6aa6f9252ea3987a3651d1fe83150c00 444 SUPERFAMILY SSF48557 4 443 3.93E-128 T 31-10-2018 IPR008948 L-Aspartase-like GO:0003824 AF_1035 4f55f910d31ff989ab870e2c79d9f01a 429 Gene3D G3DSA:3.30.450.20 139 258 5.0E-9 T 31-10-2018 AF_1035 4f55f910d31ff989ab870e2c79d9f01a 429 SUPERFAMILY SSF55785 146 246 3.49E-8 T 31-10-2018 IPR035965 PAS domain superfamily AF_1035 4f55f910d31ff989ab870e2c79d9f01a 429 Pfam PF13188 PAS domain 49 92 1.2E-4 T 31-10-2018 IPR000014 PAS domain AF_1035 4f55f910d31ff989ab870e2c79d9f01a 429 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 142 251 1.0E-9 T 31-10-2018 IPR000014 PAS domain AF_1035 4f55f910d31ff989ab870e2c79d9f01a 429 Pfam PF08448 PAS fold 149 249 2.9E-13 T 31-10-2018 IPR013656 PAS fold-4 AF_1035 4f55f910d31ff989ab870e2c79d9f01a 429 SMART SM00388 351 409 3.1E-7 T 31-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AF_1035 4f55f910d31ff989ab870e2c79d9f01a 429 Pfam PF00512 His Kinase A (phospho-acceptor) domain 353 406 4.7E-7 T 31-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AF_1035 4f55f910d31ff989ab870e2c79d9f01a 429 SMART SM00091 143 206 0.021 T 31-10-2018 IPR000014 PAS domain AF_1035 4f55f910d31ff989ab870e2c79d9f01a 429 SMART SM00091 47 109 6.9 T 31-10-2018 IPR000014 PAS domain AF_1035 4f55f910d31ff989ab870e2c79d9f01a 429 Gene3D G3DSA:1.10.287.130 301 402 4.5E-5 T 31-10-2018 AF_1839 4b86f49557d29b436225daebee983006 258 PIRSF PIRSF006250 4 258 3.5E-103 T 31-10-2018 IPR027277 Nicotinate-nucleotide pyrophosphorylase/Putative pyrophosphorylase ModD Reactome: R-HSA-196807 AF_1839 4b86f49557d29b436225daebee983006 258 Gene3D G3DSA:3.20.20.70 102 246 1.6E-87 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1839 4b86f49557d29b436225daebee983006 258 TIGRFAM TIGR00078 nadC: nicotinate-nucleotide diphosphorylase (carboxylating) 5 255 5.4E-91 T 31-10-2018 IPR004393 Nicotinate-nucleotide pyrophosphorylase GO:0004514|GO:0019363 KEGG: 00760+2.4.2.19|MetaCyc: PWY-5316|MetaCyc: PWY-5653|MetaCyc: PWY-7342|Reactome: R-HSA-196807 AF_1839 4b86f49557d29b436225daebee983006 258 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 86 255 1.4E-62 T 31-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 AF_1839 4b86f49557d29b436225daebee983006 258 Gene3D G3DSA:3.90.1170.20 7 254 1.6E-87 T 31-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 AF_1839 4b86f49557d29b436225daebee983006 258 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 2 84 3.7E-21 T 31-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 AF_1839 4b86f49557d29b436225daebee983006 258 SUPERFAMILY SSF54675 3 85 5.0E-19 T 31-10-2018 AF_1839 4b86f49557d29b436225daebee983006 258 SUPERFAMILY SSF51690 86 255 3.81E-54 T 31-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 AF_0227 66b5c27f56b8c8427e93390ecebe98ac 620 Gene3D G3DSA:3.40.190.10 434 516 3.8E-50 T 31-10-2018 AF_0227 66b5c27f56b8c8427e93390ecebe98ac 620 Gene3D G3DSA:1.20.59.10 265 346 6.1E-9 T 31-10-2018 IPR036979 Chorismate mutase domain superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AF_0227 66b5c27f56b8c8427e93390ecebe98ac 620 TIGRFAM TIGR01791 CM_archaeal: chorismate mutase 266 344 1.1E-27 T 31-10-2018 IPR010950 Chorismate mutase, archaeal KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AF_0227 66b5c27f56b8c8427e93390ecebe98ac 620 SUPERFAMILY SSF53850 353 530 1.19E-50 T 31-10-2018 AF_0227 66b5c27f56b8c8427e93390ecebe98ac 620 SUPERFAMILY SSF51735 4 133 2.42E-23 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0227 66b5c27f56b8c8427e93390ecebe98ac 620 SUPERFAMILY SSF55021 527 612 3.0E-19 T 31-10-2018 AF_0227 66b5c27f56b8c8427e93390ecebe98ac 620 Pfam PF01817 Chorismate mutase type II 270 345 2.2E-11 T 31-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AF_0227 66b5c27f56b8c8427e93390ecebe98ac 620 SUPERFAMILY SSF48600 264 341 2.75E-10 T 31-10-2018 IPR036263 Chorismate mutase type II superfamily GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AF_0227 66b5c27f56b8c8427e93390ecebe98ac 620 Gene3D G3DSA:3.40.50.720 3 149 1.8E-25 T 31-10-2018 AF_0227 66b5c27f56b8c8427e93390ecebe98ac 620 SMART SM00830 270 347 4.1E-11 T 31-10-2018 IPR002701 Chorismate mutase II, prokaryotic-type GO:0046417 KEGG: 00400+5.4.99.5|MetaCyc: PWY-3461|MetaCyc: PWY-3462|MetaCyc: PWY-6120|MetaCyc: PWY-6627|MetaCyc: PWY-7626 AF_0227 66b5c27f56b8c8427e93390ecebe98ac 620 Pfam PF02153 Prephenate dehydrogenase 35 237 9.6E-25 T 31-10-2018 IPR003099 Prephenate dehydrogenase GO:0004665|GO:0006571|GO:0008977|GO:0055114 KEGG: 00400+1.3.1.12|KEGG: 00401+1.3.1.12|MetaCyc: PWY-7303 AF_0227 66b5c27f56b8c8427e93390ecebe98ac 620 Gene3D G3DSA:3.40.190.10 357 526 3.8E-50 T 31-10-2018 AF_0227 66b5c27f56b8c8427e93390ecebe98ac 620 Pfam PF00800 Prephenate dehydratase 354 529 1.3E-55 T 31-10-2018 IPR001086 Prephenate dehydratase GO:0004664|GO:0009094 KEGG: 00400+4.2.1.51|MetaCyc: PWY-7432 AF_0227 66b5c27f56b8c8427e93390ecebe98ac 620 Pfam PF01842 ACT domain 538 596 1.3E-10 T 31-10-2018 IPR002912 ACT domain AF_0227 66b5c27f56b8c8427e93390ecebe98ac 620 SUPERFAMILY SSF48179 144 248 7.31E-21 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_0227 66b5c27f56b8c8427e93390ecebe98ac 620 Gene3D G3DSA:3.30.70.260 530 619 1.2E-17 T 31-10-2018 AF_0227 66b5c27f56b8c8427e93390ecebe98ac 620 Gene3D G3DSA:1.10.3660.10 151 264 2.0E-10 T 31-10-2018 AF_1684 fb190c3a4537240f42940e05644eee06 469 SUPERFAMILY SSF102114 181 395 1.16E-37 T 31-10-2018 AF_1684 fb190c3a4537240f42940e05644eee06 469 SMART SM00729 181 385 3.5E-37 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AF_1684 fb190c3a4537240f42940e05644eee06 469 Pfam PF04055 Radical SAM superfamily 186 335 1.6E-17 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_1684 fb190c3a4537240f42940e05644eee06 469 Gene3D G3DSA:3.80.30.20 181 390 6.9E-15 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe AF_2383 3358e2de29800f528c156fe6b693417a 217 Gene3D G3DSA:3.60.15.10 106 217 1.2E-21 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_2383 3358e2de29800f528c156fe6b693417a 217 SUPERFAMILY SSF56281 17 207 1.11E-19 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_2383 3358e2de29800f528c156fe6b693417a 217 Gene3D G3DSA:3.60.15.10 7 105 1.3E-19 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_2383 3358e2de29800f528c156fe6b693417a 217 Pfam PF00753 Metallo-beta-lactamase superfamily 37 98 1.4E-10 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_1214 f8c76a600ca634739f41e2fdae942e03 182 Gene3D G3DSA:3.40.50.1950 1 182 9.3E-68 T 31-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AF_1214 f8c76a600ca634739f41e2fdae942e03 182 Pfam PF02441 Flavoprotein 1 163 2.3E-25 T 31-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AF_1214 f8c76a600ca634739f41e2fdae942e03 182 Hamap MF_01984 Flavin prenyltransferase UbiX [ubiX]. 1 182 33.367 T 31-10-2018 IPR004507 Flavin prenyltransferase UbiX-like AF_1214 f8c76a600ca634739f41e2fdae942e03 182 SUPERFAMILY SSF52507 1 179 3.66E-55 T 31-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AF_1214 f8c76a600ca634739f41e2fdae942e03 182 TIGRFAM TIGR00421 ubiX_pad: polyprenyl P-hydroxybenzoate and phenylacrylic acid decarboxylases 2 181 9.0E-88 T 31-10-2018 IPR004507 Flavin prenyltransferase UbiX-like AF_2290 911e3432d906522203f352e5e0cffe0c 187 PRINTS PR01270 Histone deacetylase superfamily signature 72 87 1.1E-13 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_2290 911e3432d906522203f352e5e0cffe0c 187 PRINTS PR01270 Histone deacetylase superfamily signature 118 128 1.1E-13 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_2290 911e3432d906522203f352e5e0cffe0c 187 PRINTS PR01270 Histone deacetylase superfamily signature 38 61 1.1E-13 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_2290 911e3432d906522203f352e5e0cffe0c 187 Pfam PF00850 Histone deacetylase domain 6 98 5.8E-25 T 31-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_2290 911e3432d906522203f352e5e0cffe0c 187 SUPERFAMILY SSF52768 7 186 5.76E-45 T 31-10-2018 IPR023696 Ureohydrolase domain superfamily AF_2290 911e3432d906522203f352e5e0cffe0c 187 Gene3D G3DSA:3.40.800.20 1 111 5.8E-31 T 31-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_2290 911e3432d906522203f352e5e0cffe0c 187 Gene3D G3DSA:3.40.800.20 112 187 9.1E-14 T 31-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_2290 911e3432d906522203f352e5e0cffe0c 187 Pfam PF00850 Histone deacetylase domain 111 184 3.0E-9 T 31-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_0808 0a07cee2e9b7d21790e2ffdede2ec967 461 Gene3D G3DSA:1.10.45.10 417 461 5.3E-13 T 31-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 AF_0808 0a07cee2e9b7d21790e2ffdede2ec967 461 Pfam PF01565 FAD binding domain 38 174 5.3E-45 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AF_0808 0a07cee2e9b7d21790e2ffdede2ec967 461 SUPERFAMILY SSF56176 3 212 1.36E-68 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AF_0808 0a07cee2e9b7d21790e2ffdede2ec967 461 Pfam PF02913 FAD linked oxidases, C-terminal domain 211 460 2.7E-71 T 31-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AF_0808 0a07cee2e9b7d21790e2ffdede2ec967 461 Gene3D G3DSA:3.30.70.2740 336 416 3.4E-18 T 31-10-2018 AF_0808 0a07cee2e9b7d21790e2ffdede2ec967 461 Gene3D G3DSA:3.30.465.40 1 228 6.9E-69 T 31-10-2018 AF_0808 0a07cee2e9b7d21790e2ffdede2ec967 461 TIGRFAM TIGR00387 glcD: glycolate oxidase, subunit GlcD 40 459 1.5E-179 T 31-10-2018 IPR004490 Glycolate oxidase subunit GlcD GO:0008891|GO:0009339 AF_0808 0a07cee2e9b7d21790e2ffdede2ec967 461 SUPERFAMILY SSF55103 216 461 1.64E-54 T 31-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AF_0739 1c01c7a34688ab24d5d6158bfec18ae1 162 TIGRFAM TIGR01575 rimI: ribosomal-protein-alanine acetyltransferase 26 155 1.1E-41 T 31-10-2018 IPR006464 N-acetyltransferase RimI/Ard1 GO:0006474|GO:0016407 AF_0739 1c01c7a34688ab24d5d6158bfec18ae1 162 SUPERFAMILY SSF55729 17 157 9.0E-32 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase AF_0739 1c01c7a34688ab24d5d6158bfec18ae1 162 Pfam PF00583 Acetyltransferase (GNAT) family 29 136 4.1E-19 T 31-10-2018 IPR000182 GNAT domain AF_0739 1c01c7a34688ab24d5d6158bfec18ae1 162 Gene3D G3DSA:3.40.630.30 13 161 7.0E-37 T 31-10-2018 AF_0753 ce5c8a7f8bd7c8f7d0e6272ecac7ca44 488 PIRSF PIRSF030218 1 478 8.1E-152 T 31-10-2018 IPR016950 Mannosyltransferase, MA4085, predicted AF_0753 ce5c8a7f8bd7c8f7d0e6272ecac7ca44 488 TIGRFAM TIGR03663 TIGR03663: TIGR03663 family protein 6 411 4.1E-132 T 31-10-2018 IPR019962 Conserved hypothetical protein CHP03663 AF_0753 ce5c8a7f8bd7c8f7d0e6272ecac7ca44 488 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 53 212 1.0E-14 T 31-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like AF_0051 079ea83987c9151dcc4e9c27bf118314 369 SUPERFAMILY SSF53187 3 368 2.21E-45 T 31-10-2018 AF_0051 079ea83987c9151dcc4e9c27bf118314 369 Gene3D G3DSA:3.30.70.360 158 288 3.2E-61 T 31-10-2018 AF_0051 079ea83987c9151dcc4e9c27bf118314 369 Gene3D G3DSA:3.40.630.10 7 358 3.2E-61 T 31-10-2018 AF_0051 079ea83987c9151dcc4e9c27bf118314 369 Pfam PF07687 Peptidase dimerisation domain 161 266 4.5E-9 T 31-10-2018 IPR011650 Peptidase M20, dimerisation domain AF_0051 079ea83987c9151dcc4e9c27bf118314 369 Pfam PF01546 Peptidase family M20/M25/M40 62 367 3.4E-30 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 AF_0051 079ea83987c9151dcc4e9c27bf118314 369 ProSitePatterns PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family signature 1. 61 70 - T 31-10-2018 IPR001261 ArgE/DapE/ACY1/CPG2/YscS, conserved site GO:0006508|GO:0008237 AF_0051 079ea83987c9151dcc4e9c27bf118314 369 SUPERFAMILY SSF55031 161 268 1.55E-9 T 31-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain AF_2376 f8fb9fe89791c075634c048e1be9fe1e 190 Pfam PF00963 Cohesin domain 33 155 7.4E-23 T 31-10-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 AF_2376 f8fb9fe89791c075634c048e1be9fe1e 190 Gene3D G3DSA:2.60.40.680 31 161 1.3E-26 T 31-10-2018 AF_2376 f8fb9fe89791c075634c048e1be9fe1e 190 SUPERFAMILY SSF49384 32 168 1.78E-25 T 31-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AF_0183 b749007dac9b80515d2a7ce3f5656816 132 SUPERFAMILY SSF75169 11 123 2.35E-14 T 31-10-2018 IPR027396 DsrEFH-like AF_0183 b749007dac9b80515d2a7ce3f5656816 132 Gene3D G3DSA:3.40.1260.10 5 132 1.2E-22 T 31-10-2018 IPR027396 DsrEFH-like AF_0183 b749007dac9b80515d2a7ce3f5656816 132 Pfam PF13686 DsrE/DsrF/DrsH-like family 11 55 3.0E-6 T 31-10-2018 IPR032836 DsrE2-like family AF_0909 f3269dc5dec0739511798b9199b38547 257 Gene3D G3DSA:3.40.50.720 3 256 8.2E-90 T 31-10-2018 AF_0909 f3269dc5dec0739511798b9199b38547 257 SUPERFAMILY SSF51735 1 257 8.63E-41 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0909 f3269dc5dec0739511798b9199b38547 257 SUPERFAMILY SSF55347 120 227 3.27E-30 T 31-10-2018 AF_0909 f3269dc5dec0739511798b9199b38547 257 PIRSF PIRSF000161 1 257 3.3E-82 T 31-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AF_0909 f3269dc5dec0739511798b9199b38547 257 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 1 118 8.7E-36 T 31-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AF_0909 f3269dc5dec0739511798b9199b38547 257 Pfam PF05173 Dihydrodipicolinate reductase, C-terminus 121 256 9.5E-42 T 31-10-2018 IPR022663 Dihydrodipicolinate reductase, C-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AF_0909 f3269dc5dec0739511798b9199b38547 257 ProSitePatterns PS01298 Dihydrodipicolinate reductase signature. 142 159 - T 31-10-2018 IPR022664 Dihydrodipicolinate reductase, conserved site GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AF_0909 f3269dc5dec0739511798b9199b38547 257 Gene3D G3DSA:3.30.360.10 120 225 8.2E-90 T 31-10-2018 AF_0909 f3269dc5dec0739511798b9199b38547 257 TIGRFAM TIGR00036 dapB: 4-hydroxy-tetrahydrodipicolinate reductase 1 257 7.2E-107 T 31-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AF_0909 f3269dc5dec0739511798b9199b38547 257 Hamap MF_00102 4-hydroxy-tetrahydrodipicolinate reductase [dapB]. 1 257 34.397 T 31-10-2018 IPR023940 Dihydrodipicolinate reductase GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AF_2402 a435080aa3d4e0dbcaeb33480ea90a6d 517 Pfam PF04055 Radical SAM superfamily 77 273 9.7E-23 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_2402 a435080aa3d4e0dbcaeb33480ea90a6d 517 TIGRFAM TIGR01211 ELP3: radical SAM enzyme/protein acetyltransferase, ELP3 family 5 517 1.3E-254 T 31-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 AF_2402 a435080aa3d4e0dbcaeb33480ea90a6d 517 SMART SM00729 70 329 5.0E-53 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AF_2402 a435080aa3d4e0dbcaeb33480ea90a6d 517 PIRSF PIRSF005669 2 517 1.1E-232 T 31-10-2018 IPR034687 Elongator complex protein 3-like Reactome: R-HSA-3214847 AF_2402 a435080aa3d4e0dbcaeb33480ea90a6d 517 Pfam PF00583 Acetyltransferase (GNAT) family 400 506 2.0E-7 T 31-10-2018 IPR000182 GNAT domain AF_2402 a435080aa3d4e0dbcaeb33480ea90a6d 517 Pfam PF16199 Radical_SAM C-terminal domain 290 370 3.1E-25 T 31-10-2018 IPR032432 Radical SAM, C-terminal extension Reactome: R-HSA-3214847 AF_2402 a435080aa3d4e0dbcaeb33480ea90a6d 517 Gene3D G3DSA:3.40.630.30 366 516 2.6E-9 T 31-10-2018 AF_2402 a435080aa3d4e0dbcaeb33480ea90a6d 517 SUPERFAMILY SSF55729 392 512 5.41E-9 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase AF_2402 a435080aa3d4e0dbcaeb33480ea90a6d 517 Gene3D G3DSA:3.80.30.20 140 345 7.2E-16 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe AF_2402 a435080aa3d4e0dbcaeb33480ea90a6d 517 SUPERFAMILY SSF102114 122 336 7.98E-35 T 31-10-2018 AF_1917 c21e4035aadff16ded758372a6fd220c 102 SUPERFAMILY SSF101744 9 94 1.26E-26 T 31-10-2018 IPR023534 Rof/RNase P-like Reactome: R-HSA-6784531 AF_1917 c21e4035aadff16ded758372a6fd220c 102 Gene3D G3DSA:2.30.30.210 1 102 1.5E-40 T 31-10-2018 IPR036980 Ribonuclease P/MRP, subunit p29 superfamily GO:0003723|GO:0004540|GO:0008033|GO:0030677 Reactome: R-HSA-6784531 AF_1917 c21e4035aadff16ded758372a6fd220c 102 Hamap MF_00754 Ribonuclease P protein component 1 [rnp1]. 12 88 17.647 T 31-10-2018 IPR023538 Ribonuclease P protein component 1 GO:0001682|GO:0004526 AF_1917 c21e4035aadff16ded758372a6fd220c 102 SMART SM00538 4 94 1.6E-42 T 31-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 AF_1917 c21e4035aadff16ded758372a6fd220c 102 Pfam PF01868 Domain of unknown function UPF0086 9 89 6.0E-23 T 31-10-2018 IPR002730 Ribonuclease P/MRP, subunit p29 GO:0003723|GO:0004540|GO:0006396|GO:0030677 Reactome: R-HSA-6784531 AF_0454 a18eb72a6f73251a273418580fdfb797 305 Pfam PF00989 PAS fold 4 94 4.3E-5 T 31-10-2018 IPR013767 PAS fold GO:0006355 AF_0454 a18eb72a6f73251a273418580fdfb797 305 SUPERFAMILY SSF55785 3 104 4.57E-7 T 31-10-2018 IPR035965 PAS domain superfamily AF_0454 a18eb72a6f73251a273418580fdfb797 305 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 6 84 1.6E-6 T 31-10-2018 IPR000014 PAS domain AF_0454 a18eb72a6f73251a273418580fdfb797 305 Gene3D G3DSA:3.30.450.20 2 119 1.7E-9 T 31-10-2018 AF_2374 88cf51437950ea8216e79d2af539288b 157 Pfam PF00930 Dipeptidyl peptidase IV (DPP IV) N-terminal region 92 153 1.5E-5 T 31-10-2018 IPR002469 Dipeptidylpeptidase IV, N-terminal domain GO:0006508 AF_2374 88cf51437950ea8216e79d2af539288b 157 Gene3D G3DSA:2.120.10.30 47 156 2.7E-12 T 31-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AF_2374 88cf51437950ea8216e79d2af539288b 157 SUPERFAMILY SSF69304 90 151 4.84E-8 T 31-10-2018 AF_1892 9038c46aea4c308129100283009277b6 144 SUPERFAMILY SSF50249 20 142 1.46E-35 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_1892 9038c46aea4c308129100283009277b6 144 ProSitePatterns PS00055 Ribosomal protein S12 signature. 60 67 - T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1892 9038c46aea4c308129100283009277b6 144 Gene3D G3DSA:2.40.50.140 25 143 1.3E-50 T 31-10-2018 AF_1892 9038c46aea4c308129100283009277b6 144 Hamap MF_00403_A 30S ribosomal protein S12 [rpsL]. 3 144 43.215 T 31-10-2018 IPR022863 Ribosomal protein S12, archaea AF_1892 9038c46aea4c308129100283009277b6 144 PIRSF PIRSF002133 16 144 2.3E-34 T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1892 9038c46aea4c308129100283009277b6 144 Pfam PF00164 Ribosomal protein S12/S23 29 141 1.6E-48 T 31-10-2018 IPR006032 Ribosomal protein S12/S23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1892 9038c46aea4c308129100283009277b6 144 TIGRFAM TIGR00982 uS12_E_A: ribosomal protein uS12 6 144 1.3E-83 T 31-10-2018 IPR005680 Ribosomal protein S23, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0366 08357a1380d549172843f4a9b408dbba 681 Gene3D G3DSA:3.40.50.12780 62 541 5.9E-100 T 31-10-2018 AF_0366 08357a1380d549172843f4a9b408dbba 681 Pfam PF13193 AMP-binding enzyme C-terminal domain 556 635 7.6E-25 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AF_0366 08357a1380d549172843f4a9b408dbba 681 Gene3D G3DSA:3.30.300.30 543 675 3.6E-28 T 31-10-2018 AF_0366 08357a1380d549172843f4a9b408dbba 681 Pfam PF00501 AMP-binding enzyme 95 547 2.0E-94 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_0366 08357a1380d549172843f4a9b408dbba 681 SUPERFAMILY SSF56801 37 662 4.19E-162 T 31-10-2018 AF_0366 08357a1380d549172843f4a9b408dbba 681 ProSitePatterns PS00455 Putative AMP-binding domain signature. 280 291 - T 31-10-2018 IPR020845 AMP-binding, conserved site AF_0366 08357a1380d549172843f4a9b408dbba 681 TIGRFAM TIGR02188 Ac_CoA_lig_AcsA: acetate--CoA ligase 26 667 4.9E-279 T 31-10-2018 IPR011904 Acetate-CoA ligase GO:0003987|GO:0016208|GO:0019427 KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857|Reactome: R-HSA-71384 AF_0366 08357a1380d549172843f4a9b408dbba 681 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 31 88 2.4E-15 T 31-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 AF_2252 b4f0fbdf40519aa779accfd28abef3c6 390 SUPERFAMILY SSF52402 1 199 2.87E-44 T 31-10-2018 AF_2252 b4f0fbdf40519aa779accfd28abef3c6 390 TIGRFAM TIGR00032 argG: argininosuccinate synthase 2 388 9.8E-179 T 31-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AF_2252 b4f0fbdf40519aa779accfd28abef3c6 390 Gene3D G3DSA:3.40.50.620 1 167 3.6E-54 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_2252 b4f0fbdf40519aa779accfd28abef3c6 390 SUPERFAMILY SSF69864 165 388 6.93E-90 T 31-10-2018 AF_2252 b4f0fbdf40519aa779accfd28abef3c6 390 Hamap MF_00005 Argininosuccinate synthase [argG]. 1 390 49.343 T 31-10-2018 IPR023434 Argininosuccinate synthase, type 1 subfamily GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AF_2252 b4f0fbdf40519aa779accfd28abef3c6 390 Gene3D G3DSA:3.90.1260.10 168 389 2.3E-89 T 31-10-2018 IPR024074 Argininosuccinate synthetase, catalytic/multimerisation domain body GO:0004055 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AF_2252 b4f0fbdf40519aa779accfd28abef3c6 390 ProSitePatterns PS00565 Argininosuccinate synthase signature 2. 113 124 - T 31-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AF_2252 b4f0fbdf40519aa779accfd28abef3c6 390 Pfam PF00764 Arginosuccinate synthase 4 385 1.5E-181 T 31-10-2018 IPR001518 Argininosuccinate synthase GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AF_2252 b4f0fbdf40519aa779accfd28abef3c6 390 ProSitePatterns PS00564 Argininosuccinate synthase signature 1. 6 14 - T 31-10-2018 IPR018223 Argininosuccinate synthase, conserved site GO:0004055|GO:0005524|GO:0006526 KEGG: 00220+6.3.4.5|KEGG: 00250+6.3.4.5|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AF_2328 ff9954c87ab9dd0dcabf72a81912b2fb 93 Hamap MF_00122 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C [gatC]. 1 93 25.12 T 31-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AF_2328 ff9954c87ab9dd0dcabf72a81912b2fb 93 SUPERFAMILY SSF141000 1 91 1.96E-26 T 31-10-2018 IPR036113 Glu-tRNAGln amidotransferase superfamily, subunit C GO:0006450 AF_2328 ff9954c87ab9dd0dcabf72a81912b2fb 93 Gene3D G3DSA:1.10.20.60 1 91 1.8E-25 T 31-10-2018 AF_2328 ff9954c87ab9dd0dcabf72a81912b2fb 93 Pfam PF02686 Glu-tRNAGln amidotransferase C subunit 18 87 6.1E-21 T 31-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AF_2328 ff9954c87ab9dd0dcabf72a81912b2fb 93 TIGRFAM TIGR00135 gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit 2 93 1.3E-32 T 31-10-2018 IPR003837 Glu-tRNAGln amidotransferase C subunit GO:0006450 AF_0570 6f18515f9f68649ce4967ef4179ad3e6 392 ProSitePatterns PS01134 FtsZ protein signature 1. 62 96 - T 31-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 AF_0570 6f18515f9f68649ce4967ef4179ad3e6 392 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 31 189 3.0E-36 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AF_0570 6f18515f9f68649ce4967ef4179ad3e6 392 Pfam PF12327 FtsZ family, C-terminal domain 238 332 1.8E-35 T 31-10-2018 IPR024757 Cell division protein FtsZ, C-terminal AF_0570 6f18515f9f68649ce4967ef4179ad3e6 392 SUPERFAMILY SSF55307 223 338 1.28E-33 T 31-10-2018 IPR008280 Tubulin/FtsZ, C-terminal Reactome: R-HSA-380320 AF_0570 6f18515f9f68649ce4967ef4179ad3e6 392 SMART SM00864 31 221 4.1E-82 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AF_0570 6f18515f9f68649ce4967ef4179ad3e6 392 PRINTS PR00423 Cell division protein FtsZ signature 228 249 2.8E-31 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AF_0570 6f18515f9f68649ce4967ef4179ad3e6 392 PRINTS PR00423 Cell division protein FtsZ signature 116 136 2.8E-31 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AF_0570 6f18515f9f68649ce4967ef4179ad3e6 392 PRINTS PR00423 Cell division protein FtsZ signature 144 165 2.8E-31 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AF_0570 6f18515f9f68649ce4967ef4179ad3e6 392 PRINTS PR00423 Cell division protein FtsZ signature 205 227 2.8E-31 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AF_0570 6f18515f9f68649ce4967ef4179ad3e6 392 Gene3D G3DSA:3.40.50.1440 28 332 5.5E-96 T 31-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AF_0570 6f18515f9f68649ce4967ef4179ad3e6 392 Hamap MF_00909 Cell division protein FtsZ [ftsZ]. 27 362 31.503 T 31-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 AF_0570 6f18515f9f68649ce4967ef4179ad3e6 392 ProSitePatterns PS01135 FtsZ protein signature 2. 115 136 - T 31-10-2018 IPR020805 Cell division protein FtsZ, conserved site GO:0005525|GO:0005737 AF_0570 6f18515f9f68649ce4967ef4179ad3e6 392 TIGRFAM TIGR00065 ftsZ: cell division protein FtsZ 14 357 5.6E-136 T 31-10-2018 IPR000158 Cell division protein FtsZ GO:0005525 AF_0570 6f18515f9f68649ce4967ef4179ad3e6 392 SUPERFAMILY SSF52490 30 224 1.15E-56 T 31-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AF_0570 6f18515f9f68649ce4967ef4179ad3e6 392 SMART SM00865 223 340 1.9E-38 T 31-10-2018 IPR018316 Tubulin/FtsZ, 2-layer sandwich domain Reactome: R-HSA-380320 AF_1587 8a35173570c00d8a7562fb6444bee004 437 SUPERFAMILY SSF51649 149 427 2.62E-89 T 31-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AF_1587 8a35173570c00d8a7562fb6444bee004 437 Gene3D G3DSA:3.30.70.150 18 149 1.2E-38 T 31-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AF_1587 8a35173570c00d8a7562fb6444bee004 437 Gene3D G3DSA:3.20.20.110 150 437 3.3E-102 T 31-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AF_1587 8a35173570c00d8a7562fb6444bee004 437 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 155 435 1.1E-55 T 31-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AF_1587 8a35173570c00d8a7562fb6444bee004 437 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 30 145 6.8E-9 T 31-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AF_1587 8a35173570c00d8a7562fb6444bee004 437 SUPERFAMILY SSF54966 23 149 2.09E-35 T 31-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AF_1060 7f54e107a7b7f9822c49650b22809277 505 Pfam PF01935 Domain of unknown function DUF87 119 334 1.3E-42 T 31-10-2018 IPR002789 Helicase HerA, central domain AF_1060 7f54e107a7b7f9822c49650b22809277 505 SUPERFAMILY SSF52540 86 462 1.16E-45 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1060 7f54e107a7b7f9822c49650b22809277 505 Pfam PF09378 HAS barrel domain 5 84 6.2E-14 T 31-10-2018 IPR018538 Helicase HerA, barrel domain AF_1060 7f54e107a7b7f9822c49650b22809277 505 Gene3D G3DSA:3.40.50.300 142 207 3.0E-8 T 31-10-2018 AF_1060 7f54e107a7b7f9822c49650b22809277 505 Gene3D G3DSA:3.40.50.300 245 472 2.1E-49 T 31-10-2018 AF_2142 d3ac2121e076d393b7dbe30bf0b6da70 56 SUPERFAMILY SSF54862 6 54 1.73E-18 T 31-10-2018 AF_2142 d3ac2121e076d393b7dbe30bf0b6da70 56 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 37 48 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_2142 d3ac2121e076d393b7dbe30bf0b6da70 56 Pfam PF13187 4Fe-4S dicluster domain 7 51 1.1E-9 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_2142 d3ac2121e076d393b7dbe30bf0b6da70 56 Gene3D G3DSA:3.30.70.20 5 54 9.8E-15 T 31-10-2018 AF_0837 384b9eea0d7190771f6720fdac9ee312 344 SUPERFAMILY SSF55315 237 342 5.18E-25 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like AF_0837 384b9eea0d7190771f6720fdac9ee312 344 Pfam PF03465 eRF1 domain 3 247 342 1.3E-21 T 31-10-2018 IPR005142 eRF1 domain 3 AF_0837 384b9eea0d7190771f6720fdac9ee312 344 SMART SM01194 1 124 1.1E-41 T 31-10-2018 IPR005140 eRF1 domain 1/Pelota-like AF_0837 384b9eea0d7190771f6720fdac9ee312 344 Pfam PF03464 eRF1 domain 2 181 238 3.1E-7 T 31-10-2018 IPR005141 eRF1 domain 2 AF_0837 384b9eea0d7190771f6720fdac9ee312 344 SUPERFAMILY SSF53137 127 241 9.16E-24 T 31-10-2018 AF_0837 384b9eea0d7190771f6720fdac9ee312 344 Hamap MF_01853 Protein pelota homolog [pelA]. 2 342 34.318 T 31-10-2018 IPR023521 Translation release factor pelota, archaea GO:0070481|GO:0070966|GO:0071025 AF_0837 384b9eea0d7190771f6720fdac9ee312 344 TIGRFAM TIGR00111 pelota: mRNA surveillance protein pelota 1 342 1.2E-150 T 31-10-2018 IPR004405 Translation release factor pelota GO:0070481|GO:0070966|GO:0071025 AF_0837 384b9eea0d7190771f6720fdac9ee312 344 Gene3D G3DSA:3.30.1330.30 246 344 1.9E-37 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like AF_0837 384b9eea0d7190771f6720fdac9ee312 344 Pfam PF03463 eRF1 domain 1 3 122 4.8E-28 T 31-10-2018 IPR005140 eRF1 domain 1/Pelota-like AF_0837 384b9eea0d7190771f6720fdac9ee312 344 Gene3D G3DSA:3.30.420.60 129 245 1.5E-28 T 31-10-2018 AF_0837 384b9eea0d7190771f6720fdac9ee312 344 SUPERFAMILY SSF159065 6 123 7.85E-33 T 31-10-2018 IPR038069 Pelota/DOM34, N-terminal domain AF_0837 384b9eea0d7190771f6720fdac9ee312 344 Gene3D G3DSA:2.30.30.870 1 128 3.4E-46 T 31-10-2018 IPR038069 Pelota/DOM34, N-terminal domain AF_2244 f4223ee0a7359372d941d42256696dd6 402 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 224 3.9E-32 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AF_2244 f4223ee0a7359372d941d42256696dd6 402 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 386 1.0E-50 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AF_2244 f4223ee0a7359372d941d42256696dd6 402 Gene3D G3DSA:1.10.540.10 4 125 8.3E-43 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AF_2244 f4223ee0a7359372d941d42256696dd6 402 SUPERFAMILY SSF47203 234 389 1.55E-52 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AF_2244 f4223ee0a7359372d941d42256696dd6 402 SUPERFAMILY SSF56645 7 247 1.44E-90 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AF_2244 f4223ee0a7359372d941d42256696dd6 402 Gene3D G3DSA:2.40.110.10 126 240 1.8E-49 T 31-10-2018 AF_2244 f4223ee0a7359372d941d42256696dd6 402 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 344 363 - T 31-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AF_2244 f4223ee0a7359372d941d42256696dd6 402 Gene3D G3DSA:1.20.140.10 241 392 1.4E-48 T 31-10-2018 AF_2244 f4223ee0a7359372d941d42256696dd6 402 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 13 123 5.0E-37 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AF_2244 f4223ee0a7359372d941d42256696dd6 402 PIRSF PIRSF016578 7 394 1.1E-18 T 31-10-2018 AF_2425 8cf1443d1113166903c5f455fdee4f45 324 Gene3D G3DSA:1.10.8.300 206 314 2.7E-35 T 31-10-2018 AF_2425 8cf1443d1113166903c5f455fdee4f45 324 Gene3D G3DSA:3.40.50.300 24 189 7.2E-41 T 31-10-2018 AF_2425 8cf1443d1113166903c5f455fdee4f45 324 PIRSF PIRSF002849 2 319 4.0E-130 T 31-10-2018 AF_2425 8cf1443d1113166903c5f455fdee4f45 324 SUPERFAMILY SSF52540 16 289 1.98E-42 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2425 8cf1443d1113166903c5f455fdee4f45 324 Pfam PF07726 ATPase family associated with various cellular activities (AAA) 44 171 4.1E-61 T 31-10-2018 IPR011703 ATPase, AAA-3 GO:0005524|GO:0016887 AF_1712 ba742a574426881fdc911c6140daebcf 71 Gene3D G3DSA:4.10.1150.10 1 71 7.0E-14 T 31-10-2018 IPR024069 AF2212-like domain superfamily AF_1712 ba742a574426881fdc911c6140daebcf 71 Pfam PF01954 Protein of unknown function DUF104 1 53 3.3E-17 T 31-10-2018 IPR008203 Uncharacterised protein family UPF0165 AF_1712 ba742a574426881fdc911c6140daebcf 71 SUPERFAMILY SSF141694 1 45 1.6E-12 T 31-10-2018 AF_1771 2df3bf4143a09c6626f7a1b5fd391274 323 Gene3D G3DSA:3.40.50.300 1 320 6.9E-96 T 31-10-2018 AF_1771 2df3bf4143a09c6626f7a1b5fd391274 323 SUPERFAMILY SSF52540 1 255 1.12E-73 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1771 2df3bf4143a09c6626f7a1b5fd391274 323 SMART SM00382 41 242 6.1E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1771 2df3bf4143a09c6626f7a1b5fd391274 323 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 234 317 6.9E-27 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AF_1771 2df3bf4143a09c6626f7a1b5fd391274 323 ProSitePatterns PS00211 ABC transporters family signature. 157 171 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_1771 2df3bf4143a09c6626f7a1b5fd391274 323 Pfam PF00005 ABC transporter 33 184 1.1E-33 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_1771 2df3bf4143a09c6626f7a1b5fd391274 323 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 236 299 5.9E-19 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AF_1730 2f9d2c1e1c08f6b9c62300c9ff3df332 265 TIGRFAM TIGR00071 hisT_truA: tRNA pseudouridine(38-40) synthase 3 218 1.7E-71 T 31-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AF_1730 2f9d2c1e1c08f6b9c62300c9ff3df332 265 PIRSF PIRSF001430 1 239 6.0E-72 T 31-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AF_1730 2f9d2c1e1c08f6b9c62300c9ff3df332 265 Gene3D G3DSA:3.30.70.660 96 222 1.3E-30 T 31-10-2018 IPR020095 Pseudouridine synthase I, TruA, C-terminal GO:0003723|GO:0009982 AF_1730 2f9d2c1e1c08f6b9c62300c9ff3df332 265 Gene3D G3DSA:3.30.70.580 1 95 5.6E-26 T 31-10-2018 AF_1730 2f9d2c1e1c08f6b9c62300c9ff3df332 265 Pfam PF01416 tRNA pseudouridine synthase 122 224 4.6E-27 T 31-10-2018 IPR020097 Pseudouridine synthase I, TruA, alpha/beta domain GO:0001522|GO:0003723|GO:0009451|GO:0009982 AF_1730 2f9d2c1e1c08f6b9c62300c9ff3df332 265 Hamap MF_00171 tRNA pseudouridine synthase A [truA]. 2 223 31.751 T 31-10-2018 IPR001406 Pseudouridine synthase I, TruA GO:0001522|GO:0003723|GO:0009451|GO:0009982 AF_1730 2f9d2c1e1c08f6b9c62300c9ff3df332 265 SUPERFAMILY SSF55120 2 231 5.18E-71 T 31-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AF_1032 95bd90035ac37f2d171a744a5023e200 886 Pfam PF04423 Rad50 zinc hook motif 417 467 3.0E-15 T 31-10-2018 IPR013134 RAD50, zinc hook Reactome: R-HSA-2559586|Reactome: R-HSA-5685938|Reactome: R-HSA-5685939|Reactome: R-HSA-5685942|Reactome: R-HSA-5693548|Reactome: R-HSA-5693554|Reactome: R-HSA-5693565|Reactome: R-HSA-5693568|Reactome: R-HSA-5693571|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 AF_1032 95bd90035ac37f2d171a744a5023e200 886 SUPERFAMILY SSF52540 4 300 1.06E-17 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1032 95bd90035ac37f2d171a744a5023e200 886 Gene3D G3DSA:1.10.287.510 388 499 5.9E-24 T 31-10-2018 AF_1032 95bd90035ac37f2d171a744a5023e200 886 SUPERFAMILY SSF75712 390 487 6.54E-18 T 31-10-2018 AF_1032 95bd90035ac37f2d171a744a5023e200 886 Gene3D G3DSA:3.40.50.300 676 884 3.9E-39 T 31-10-2018 AF_1032 95bd90035ac37f2d171a744a5023e200 886 Gene3D G3DSA:3.40.50.300 2 229 1.0E-39 T 31-10-2018 AF_1032 95bd90035ac37f2d171a744a5023e200 886 Hamap MF_00449 DNA double-strand break repair Rad50 ATPase [rad50]. 2 882 13.475 T 31-10-2018 IPR022982 DNA double-strand break repair Rad50 ATPase, archaeal type AF_1032 95bd90035ac37f2d171a744a5023e200 886 SUPERFAMILY SSF52540 5 876 2.19E-28 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1032 95bd90035ac37f2d171a744a5023e200 886 Pfam PF13476 AAA domain 6 274 3.6E-18 T 31-10-2018 IPR038729 Rad50/SbcC-type AAA domain AF_2431 096a94b090b869b7e47e59accf43233b 157 Gene3D G3DSA:3.50.20.10 1 156 1.3E-46 T 31-10-2018 IPR016105 Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AF_2431 096a94b090b869b7e47e59accf43233b 157 Pfam PF01862 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) 4 156 4.8E-54 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AF_2431 096a94b090b869b7e47e59accf43233b 157 PIRSF PIRSF005216 1 157 9.9E-59 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AF_2431 096a94b090b869b7e47e59accf43233b 157 TIGRFAM TIGR00286 TIGR00286: arginine decarboxylase, pyruvoyl-dependent 3 157 9.3E-75 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AF_2431 096a94b090b869b7e47e59accf43233b 157 SUPERFAMILY SSF56271 3 156 7.32E-50 T 31-10-2018 IPR016104 Pyruvoyl-dependent histidine/arginine decarboxylase GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AF_2431 096a94b090b869b7e47e59accf43233b 157 Hamap MF_01404 Pyruvoyl-dependent arginine decarboxylase [pdaD]. 1 157 60.844 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AF_2431 096a94b090b869b7e47e59accf43233b 157 ProDom PD010449 DECARBOXYLASE PYRUVOYL-DEPENDENT ARGININE SUBUNIT ALPHA CONTAINS: BETA PVLARGDC LYA DECARBOX 5 139 1.0E-74 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AF_0200 b5246b956adf9dd7a1ee500522e02fe3 601 Pfam PF00501 AMP-binding enzyme 23 452 6.0E-93 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_0200 b5246b956adf9dd7a1ee500522e02fe3 601 Gene3D G3DSA:3.40.50.12780 306 443 1.7E-37 T 31-10-2018 AF_0200 b5246b956adf9dd7a1ee500522e02fe3 601 SUPERFAMILY SSF56801 16 600 6.67E-117 T 31-10-2018 AF_0200 b5246b956adf9dd7a1ee500522e02fe3 601 ProSitePatterns PS00455 Putative AMP-binding domain signature. 169 180 - T 31-10-2018 IPR020845 AMP-binding, conserved site AF_0200 b5246b956adf9dd7a1ee500522e02fe3 601 Gene3D G3DSA:3.40.50.12780 3 290 1.1E-51 T 31-10-2018 AF_1841 65d37aeb7a819ae4ac8cfe1f5d199fd8 238 Pfam PF00005 ABC transporter 25 170 3.8E-35 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_1841 65d37aeb7a819ae4ac8cfe1f5d199fd8 238 Gene3D G3DSA:3.40.50.300 5 237 4.7E-66 T 31-10-2018 AF_1841 65d37aeb7a819ae4ac8cfe1f5d199fd8 238 SUPERFAMILY SSF52540 7 230 2.66E-55 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1841 65d37aeb7a819ae4ac8cfe1f5d199fd8 238 ProSitePatterns PS00211 ABC transporters family signature. 142 156 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_1841 65d37aeb7a819ae4ac8cfe1f5d199fd8 238 SMART SM00382 33 214 8.9E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0677 bd8ae29c812ef439e76c95b08ca83ad7 643 Pfam PF13193 AMP-binding enzyme C-terminal domain 525 603 2.0E-27 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AF_0677 bd8ae29c812ef439e76c95b08ca83ad7 643 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 5 61 3.8E-18 T 31-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 AF_0677 bd8ae29c812ef439e76c95b08ca83ad7 643 Gene3D G3DSA:3.40.50.12780 36 510 3.2E-88 T 31-10-2018 AF_0677 bd8ae29c812ef439e76c95b08ca83ad7 643 SUPERFAMILY SSF56801 4 635 6.67E-153 T 31-10-2018 AF_0677 bd8ae29c812ef439e76c95b08ca83ad7 643 Gene3D G3DSA:3.30.300.30 512 642 8.2E-30 T 31-10-2018 AF_0677 bd8ae29c812ef439e76c95b08ca83ad7 643 Pfam PF00501 AMP-binding enzyme 64 516 2.1E-82 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_1736 dc3913a0225fafe1330c5f84428bbcad 436 Gene3D G3DSA:1.10.8.660 385 436 3.8E-18 T 31-10-2018 AF_1736 dc3913a0225fafe1330c5f84428bbcad 436 SUPERFAMILY SSF55035 127 233 7.06E-33 T 31-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AF_1736 dc3913a0225fafe1330c5f84428bbcad 436 Pfam PF00368 Hydroxymethylglutaryl-coenzyme A reductase 31 395 8.1E-116 T 31-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AF_1736 dc3913a0225fafe1330c5f84428bbcad 436 Gene3D G3DSA:3.30.70.420 126 235 4.9E-134 T 31-10-2018 IPR009023 Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily GO:0050662 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AF_1736 dc3913a0225fafe1330c5f84428bbcad 436 ProSitePatterns PS00318 Hydroxymethylglutaryl-coenzyme A reductases signature 2. 334 341 - T 31-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AF_1736 dc3913a0225fafe1330c5f84428bbcad 436 Gene3D G3DSA:3.90.770.10 31 381 4.9E-134 T 31-10-2018 IPR023074 Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AF_1736 dc3913a0225fafe1330c5f84428bbcad 436 ProSitePatterns PS01192 Hydroxymethylglutaryl-coenzyme A reductases signature 3. 380 393 - T 31-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AF_1736 dc3913a0225fafe1330c5f84428bbcad 436 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 66 87 3.9E-8 T 31-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AF_1736 dc3913a0225fafe1330c5f84428bbcad 436 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 93 113 3.9E-8 T 31-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AF_1736 dc3913a0225fafe1330c5f84428bbcad 436 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 189 207 3.9E-8 T 31-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AF_1736 dc3913a0225fafe1330c5f84428bbcad 436 PRINTS PR00071 Hydroxymethylglutaryl-coenzyme A reductase signature 322 343 3.9E-8 T 31-10-2018 IPR002202 Hydroxymethylglutaryl-CoA reductase, class I/II GO:0004420|GO:0015936|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AF_1736 dc3913a0225fafe1330c5f84428bbcad 436 ProSitePatterns PS00066 Hydroxymethylglutaryl-coenzyme A reductases signature 1. 191 205 - T 31-10-2018 IPR023076 Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site GO:0004420|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AF_1736 dc3913a0225fafe1330c5f84428bbcad 436 TIGRFAM TIGR00532 HMG_CoA_R_NAD: hydroxymethylglutaryl-CoA reductase, degradative 1 395 2.2E-230 T 31-10-2018 IPR004553 Hydroxymethylglutaryl-CoA reductase, bacterial-type GO:0015936|GO:0016616|GO:0050662 AF_1736 dc3913a0225fafe1330c5f84428bbcad 436 SUPERFAMILY SSF56542 23 435 1.83E-106 T 31-10-2018 IPR009029 Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily GO:0015936|GO:0016616|GO:0050662|GO:0055114 KEGG: 00900+1.1.1.34|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-1989781|Reactome: R-HSA-2426168 AF_1389 348a639685dae9e2fca70079b8a41cbd 236 SMART SM00382 26 219 4.1E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1389 348a639685dae9e2fca70079b8a41cbd 236 Pfam PF00005 ABC transporter 19 162 9.7E-32 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_1389 348a639685dae9e2fca70079b8a41cbd 236 SUPERFAMILY SSF52540 3 226 4.97E-57 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1389 348a639685dae9e2fca70079b8a41cbd 236 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_1389 348a639685dae9e2fca70079b8a41cbd 236 Gene3D G3DSA:3.40.50.300 1 235 4.1E-62 T 31-10-2018 AF_1152 b9ebce20adf4bb5e6d174d13c55db713 357 Gene3D G3DSA:3.30.70.3190 250 357 8.1E-29 T 31-10-2018 AF_1152 b9ebce20adf4bb5e6d174d13c55db713 357 SUPERFAMILY SSF55120 246 356 1.76E-15 T 31-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AF_1152 b9ebce20adf4bb5e6d174d13c55db713 357 TIGRFAM TIGR01213 pseudo_Pus10arc: tRNA pseudouridine(54/55) synthase 17 356 3.6E-103 T 31-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 AF_1152 b9ebce20adf4bb5e6d174d13c55db713 357 Gene3D G3DSA:3.30.70.2510 118 249 6.2E-38 T 31-10-2018 AF_1152 b9ebce20adf4bb5e6d174d13c55db713 357 Hamap MF_01893 tRNA pseudouridine synthase Pus10 [pus10]. 2 357 52.531 T 31-10-2018 IPR005912 tRNA pseudouridine synthase, Pus10 GO:0000049|GO:0001522|GO:0006400|GO:0009982 AF_1152 b9ebce20adf4bb5e6d174d13c55db713 357 Pfam PF02926 THUMP domain 18 118 2.5E-18 T 31-10-2018 IPR004114 THUMP domain GO:0003723 AF_1826 81532c97b8ae9ad23202601f544750b6 649 Pfam PF00662 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus 82 130 1.4E-6 T 31-10-2018 IPR001516 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1826 81532c97b8ae9ad23202601f544750b6 649 Pfam PF00361 Proton-conducting membrane transporter 202 443 2.9E-34 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1826 81532c97b8ae9ad23202601f544750b6 649 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 95 120 5.9E-19 T 31-10-2018 AF_1826 81532c97b8ae9ad23202601f544750b6 649 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 257 278 5.9E-19 T 31-10-2018 AF_1826 81532c97b8ae9ad23202601f544750b6 649 PRINTS PR01434 NADH-ubiquinone oxidoreductase chain 5 signature 279 305 5.9E-19 T 31-10-2018 AF_2294 8261a8824124af7ecf04c2e2137b6a0a 388 SUPERFAMILY SSF103473 5 381 6.15E-31 T 31-10-2018 IPR036259 MFS transporter superfamily AF_2294 8261a8824124af7ecf04c2e2137b6a0a 388 TIGRFAM TIGR00903 2A0129: major facilitator 4 family protein 17 379 1.6E-204 T 31-10-2018 IPR005277 Uncharacterised protein family, Major Facilitator Superfamily MSF4 AF_2294 8261a8824124af7ecf04c2e2137b6a0a 388 Pfam PF07690 Major Facilitator Superfamily 13 343 2.4E-23 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AF_2294 8261a8824124af7ecf04c2e2137b6a0a 388 Gene3D G3DSA:1.20.1250.20 3 376 1.6E-21 T 31-10-2018 AF_2358 112178659f06af1f1a41c4943ca9bacd 392 Gene3D G3DSA:1.10.443.10 208 380 2.9E-7 T 31-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AF_2358 112178659f06af1f1a41c4943ca9bacd 392 Pfam PF00589 Phage integrase family 219 365 2.8E-5 T 31-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AF_2358 112178659f06af1f1a41c4943ca9bacd 392 SUPERFAMILY SSF56349 78 375 2.09E-10 T 31-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AF_2421 9d10512b8b78cea5f1dbd58a96c2635b 932 SUPERFAMILY SSF52374 3 676 1.1E-102 T 31-10-2018 AF_2421 9d10512b8b78cea5f1dbd58a96c2635b 932 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 392 669 2.3E-19 T 31-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_2421 9d10512b8b78cea5f1dbd58a96c2635b 932 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 10 319 8.3E-45 T 31-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_2421 9d10512b8b78cea5f1dbd58a96c2635b 932 Gene3D G3DSA:1.10.10.720 832 883 9.4E-32 T 31-10-2018 AF_2421 9d10512b8b78cea5f1dbd58a96c2635b 932 SUPERFAMILY SSF47323 679 869 1.78E-33 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_2421 9d10512b8b78cea5f1dbd58a96c2635b 932 Gene3D G3DSA:3.40.50.620 7 668 8.0E-285 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_2421 9d10512b8b78cea5f1dbd58a96c2635b 932 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 38 49 - T 31-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_2421 9d10512b8b78cea5f1dbd58a96c2635b 932 Hamap MF_00049_A Leucine--tRNA ligase [leuS]. 4 932 18.054 T 31-10-2018 IPR020791 Leucine-tRNA ligase, archaeal GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4 AF_2421 9d10512b8b78cea5f1dbd58a96c2635b 932 Gene3D G3DSA:1.10.730.10 670 777 3.7E-24 T 31-10-2018 AF_2421 9d10512b8b78cea5f1dbd58a96c2635b 932 TIGRFAM TIGR00395 leuS_arch: leucine--tRNA ligase 6 931 0.0 T 31-10-2018 IPR004493 Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic GO:0000166|GO:0004823|GO:0005524|GO:0005737|GO:0006429 KEGG: 00970+6.1.1.4|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AF_2421 9d10512b8b78cea5f1dbd58a96c2635b 932 Pfam PF08264 Anticodon-binding domain of tRNA 703 819 6.8E-23 T 31-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AF_2421 9d10512b8b78cea5f1dbd58a96c2635b 932 Gene3D G3DSA:3.90.740.10 198 438 8.0E-285 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AF_2421 9d10512b8b78cea5f1dbd58a96c2635b 932 Gene3D G3DSA:3.30.2320.20 804 931 9.4E-32 T 31-10-2018 AF_2421 9d10512b8b78cea5f1dbd58a96c2635b 932 SUPERFAMILY SSF50677 203 430 1.22E-33 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AF_0335 f91fa4a5a3b46f304517c5cffe83c5a2 245 SUPERFAMILY SSF55979 123 243 4.52E-28 T 31-10-2018 AF_0335 f91fa4a5a3b46f304517c5cffe83c5a2 245 Pfam PF02747 Proliferating cell nuclear antigen, C-terminal domain 122 231 4.1E-9 T 31-10-2018 IPR022649 Proliferating cell nuclear antigen, PCNA, C-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 AF_0335 f91fa4a5a3b46f304517c5cffe83c5a2 245 Pfam PF00705 Proliferating cell nuclear antigen, N-terminal domain 6 95 1.7E-11 T 31-10-2018 IPR022648 Proliferating cell nuclear antigen, PCNA, N-terminal GO:0003677|GO:0006275 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 AF_0335 f91fa4a5a3b46f304517c5cffe83c5a2 245 Hamap MF_00317 DNA polymerase sliding clamp [pcn]. 1 242 26.921 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 AF_0335 f91fa4a5a3b46f304517c5cffe83c5a2 245 Gene3D G3DSA:3.70.10.10 1 245 5.7E-89 T 31-10-2018 AF_0335 f91fa4a5a3b46f304517c5cffe83c5a2 245 ProSitePatterns PS01251 Proliferating cell nuclear antigen signature 1. 33 56 - T 31-10-2018 IPR022659 Proliferating cell nuclear antigen, PCNA, conserved site Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 AF_0335 f91fa4a5a3b46f304517c5cffe83c5a2 245 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 9 28 2.1E-12 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 AF_0335 f91fa4a5a3b46f304517c5cffe83c5a2 245 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 33 51 2.1E-12 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 AF_0335 f91fa4a5a3b46f304517c5cffe83c5a2 245 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 55 79 2.1E-12 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 AF_0335 f91fa4a5a3b46f304517c5cffe83c5a2 245 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 228 245 2.1E-12 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 AF_0335 f91fa4a5a3b46f304517c5cffe83c5a2 245 PRINTS PR00339 Proliferating cell nuclear antigen (cyclin) signature 189 203 2.1E-12 T 31-10-2018 IPR000730 Proliferating cell nuclear antigen, PCNA GO:0003677|GO:0006275|GO:0030337 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1362277|Reactome: R-HSA-174411|Reactome: R-HSA-174414|Reactome: R-HSA-174417|Reactome: R-HSA-174437|Reactome: R-HSA-4615885|Reactome: R-HSA-5358565|Reactome: R-HSA-5358606|Reactome: R-HSA-539107|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804114|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183|Reactome: R-HSA-8866654 AF_0335 f91fa4a5a3b46f304517c5cffe83c5a2 245 SUPERFAMILY SSF55979 1 122 1.16E-27 T 31-10-2018 AF_1698 f7dcaa497958eb4b742656b5040c6d57 287 Pfam PF01161 Phosphatidylethanolamine-binding protein 150 283 1.7E-29 T 31-10-2018 IPR008914 Phosphatidylethanolamine-binding protein AF_1698 f7dcaa497958eb4b742656b5040c6d57 287 SUPERFAMILY SSF49777 143 283 1.83E-40 T 31-10-2018 IPR036610 PEBP-like superfamily AF_1698 f7dcaa497958eb4b742656b5040c6d57 287 TIGRFAM TIGR00481 TIGR00481: Raf kinase inhibitor-like protein, YbhB/YbcL family 144 283 1.9E-53 T 31-10-2018 IPR005247 YbhB/YbcL AF_1698 f7dcaa497958eb4b742656b5040c6d57 287 Gene3D G3DSA:3.90.280.10 138 286 4.6E-48 T 31-10-2018 IPR036610 PEBP-like superfamily AF_1190 b1a9460704e6299bcbd9f71703be9b5f 295 Gene3D G3DSA:3.40.50.720 1 190 7.8E-72 T 31-10-2018 AF_1190 b1a9460704e6299bcbd9f71703be9b5f 295 SUPERFAMILY SSF51735 6 190 1.26E-59 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1190 b1a9460704e6299bcbd9f71703be9b5f 295 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 9 189 3.1E-69 T 31-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_1190 b1a9460704e6299bcbd9f71703be9b5f 295 SUPERFAMILY SSF48179 191 291 3.57E-25 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_1190 b1a9460704e6299bcbd9f71703be9b5f 295 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 192 290 6.0E-28 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_1190 b1a9460704e6299bcbd9f71703be9b5f 295 Gene3D G3DSA:1.10.1040.10 192 295 4.9E-27 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AF_1190 b1a9460704e6299bcbd9f71703be9b5f 295 PIRSF PIRSF000105 1 295 4.1E-85 T 31-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 AF_0800 595274936e48cf325f55ca45effb4533 419 PRINTS PR01181 Diaminopimelate decarboxylase signature 71 88 6.2E-26 T 31-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AF_0800 595274936e48cf325f55ca45effb4533 419 PRINTS PR01181 Diaminopimelate decarboxylase signature 159 168 6.2E-26 T 31-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AF_0800 595274936e48cf325f55ca45effb4533 419 PRINTS PR01181 Diaminopimelate decarboxylase signature 298 316 6.2E-26 T 31-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AF_0800 595274936e48cf325f55ca45effb4533 419 PRINTS PR01181 Diaminopimelate decarboxylase signature 380 402 6.2E-26 T 31-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AF_0800 595274936e48cf325f55ca45effb4533 419 ProSitePatterns PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2. 223 236 - T 31-10-2018 IPR022657 Orn/DAP/Arg decarboxylase 2, conserved site AF_0800 595274936e48cf325f55ca45effb4533 419 SUPERFAMILY SSF51419 24 282 3.34E-75 T 31-10-2018 IPR029066 PLP-binding barrel AF_0800 595274936e48cf325f55ca45effb4533 419 TIGRFAM TIGR01048 lysA: diaminopimelate decarboxylase 4 412 2.2E-169 T 31-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AF_0800 595274936e48cf325f55ca45effb4533 419 Gene3D G3DSA:2.40.37.10 11 409 1.8E-149 T 31-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AF_0800 595274936e48cf325f55ca45effb4533 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 53 71 5.9E-23 T 31-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AF_0800 595274936e48cf325f55ca45effb4533 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 185 198 5.9E-23 T 31-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AF_0800 595274936e48cf325f55ca45effb4533 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 73 85 5.9E-23 T 31-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AF_0800 595274936e48cf325f55ca45effb4533 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 370 383 5.9E-23 T 31-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AF_0800 595274936e48cf325f55ca45effb4533 419 PRINTS PR01179 Ornithine/diaminopimelate/arginine (ODA) decarboxylase family signature 271 290 5.9E-23 T 31-10-2018 IPR000183 Ornithine/DAP/Arg decarboxylase GO:0003824 AF_0800 595274936e48cf325f55ca45effb4533 419 ProSitePatterns PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site. 53 71 - T 31-10-2018 IPR022653 Orn/DAP/Arg decarboxylase 2, pyridoxal-phosphate binding site AF_0800 595274936e48cf325f55ca45effb4533 419 Gene3D G3DSA:3.20.20.10 32 276 1.8E-149 T 31-10-2018 IPR029066 PLP-binding barrel AF_0800 595274936e48cf325f55ca45effb4533 419 SUPERFAMILY SSF50621 265 415 3.98E-55 T 31-10-2018 IPR009006 Alanine racemase/group IV decarboxylase, C-terminal GO:0003824 AF_0800 595274936e48cf325f55ca45effb4533 419 Pfam PF00278 Pyridoxal-dependent decarboxylase, C-terminal sheet domain 282 370 2.5E-27 T 31-10-2018 IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal GO:0003824 AF_0800 595274936e48cf325f55ca45effb4533 419 Pfam PF02784 Pyridoxal-dependent decarboxylase, pyridoxal binding domain 34 281 3.4E-55 T 31-10-2018 IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal GO:0003824 AF_0800 595274936e48cf325f55ca45effb4533 419 Hamap MF_02120 Diaminopimelate decarboxylase [lysA]. 13 413 41.889 T 31-10-2018 IPR002986 Diaminopimelate decarboxylase, LysA GO:0008836|GO:0009089 KEGG: 00300+4.1.1.20|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AF_1436 c935ec91e3d757b3facaaf2886b55136 220 Pfam PF03358 NADPH-dependent FMN reductase 1 146 8.9E-26 T 31-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AF_1436 c935ec91e3d757b3facaaf2886b55136 220 SUPERFAMILY SSF52218 1 177 2.79E-47 T 31-10-2018 IPR029039 Flavoprotein-like superfamily AF_1436 c935ec91e3d757b3facaaf2886b55136 220 Gene3D G3DSA:3.40.50.360 2 220 3.0E-62 T 31-10-2018 IPR029039 Flavoprotein-like superfamily AF_0971 4e33e20baf0eb3839bae417e81803577 600 Pfam PF03445 Putative nucleotidyltransferase DUF294 290 421 4.0E-35 T 31-10-2018 IPR005105 Protein-PII uridylyltransferase, N-terminal GO:0008773 AF_0971 4e33e20baf0eb3839bae417e81803577 600 Gene3D G3DSA:3.10.580.10 137 304 8.5E-30 T 31-10-2018 AF_0971 4e33e20baf0eb3839bae417e81803577 600 SMART SM00116 152 200 5.1E-5 T 31-10-2018 IPR000644 CBS domain AF_0971 4e33e20baf0eb3839bae417e81803577 600 SMART SM00116 216 263 5.0E-6 T 31-10-2018 IPR000644 CBS domain AF_0971 4e33e20baf0eb3839bae417e81803577 600 SUPERFAMILY SSF51206 5 117 2.36E-22 T 31-10-2018 IPR018490 Cyclic nucleotide-binding-like AF_0971 4e33e20baf0eb3839bae417e81803577 600 Gene3D G3DSA:1.20.120.330 498 596 2.9E-5 T 31-10-2018 AF_0971 4e33e20baf0eb3839bae417e81803577 600 Pfam PF00571 CBS domain 145 199 6.0E-10 T 31-10-2018 IPR000644 CBS domain AF_0971 4e33e20baf0eb3839bae417e81803577 600 Pfam PF00571 CBS domain 209 260 1.9E-10 T 31-10-2018 IPR000644 CBS domain AF_0971 4e33e20baf0eb3839bae417e81803577 600 Pfam PF00027 Cyclic nucleotide-binding domain 33 109 5.0E-11 T 31-10-2018 IPR000595 Cyclic nucleotide-binding domain AF_0971 4e33e20baf0eb3839bae417e81803577 600 SMART SM00100 13 124 1.3E-8 T 31-10-2018 IPR000595 Cyclic nucleotide-binding domain AF_0971 4e33e20baf0eb3839bae417e81803577 600 Gene3D G3DSA:2.60.120.10 5 124 4.9E-20 T 31-10-2018 IPR014710 RmlC-like jelly roll fold AF_0971 4e33e20baf0eb3839bae417e81803577 600 Pfam PF10335 Putative nucleotidyltransferase substrate binding domain 457 594 2.6E-40 T 31-10-2018 IPR018821 Domain of unknown function DUF294, putative nucleotidyltransferase substrate-binding AF_0971 4e33e20baf0eb3839bae417e81803577 600 SUPERFAMILY SSF54631 143 262 4.67E-29 T 31-10-2018 AF_0285 4df1ff3c5f1c4c90772a09def80fce0f 658 Gene3D G3DSA:3.40.50.720 3 189 3.0E-77 T 31-10-2018 AF_0285 4df1ff3c5f1c4c90772a09def80fce0f 658 SUPERFAMILY SSF52096 400 657 9.52E-90 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AF_0285 4df1ff3c5f1c4c90772a09def80fce0f 658 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 278 4.8E-28 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_0285 4df1ff3c5f1c4c90772a09def80fce0f 658 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 297 388 3.7E-22 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_0285 4df1ff3c5f1c4c90772a09def80fce0f 658 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 499 519 - T 31-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 AF_0285 4df1ff3c5f1c4c90772a09def80fce0f 658 ProSitePatterns PS00067 3-hydroxyacyl-CoA dehydrogenase signature. 185 210 - T 31-10-2018 IPR006180 3-hydroxyacyl-CoA dehydrogenase, conserved site GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_0285 4df1ff3c5f1c4c90772a09def80fce0f 658 Gene3D G3DSA:1.10.1040.10 190 296 1.5E-27 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AF_0285 4df1ff3c5f1c4c90772a09def80fce0f 658 Gene3D G3DSA:3.90.226.10 387 600 2.5E-74 T 31-10-2018 AF_0285 4df1ff3c5f1c4c90772a09def80fce0f 658 SUPERFAMILY SSF48179 297 401 1.11E-25 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_0285 4df1ff3c5f1c4c90772a09def80fce0f 658 SUPERFAMILY SSF48179 188 286 2.3E-26 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_0285 4df1ff3c5f1c4c90772a09def80fce0f 658 Gene3D G3DSA:1.10.1040.10 299 384 2.3E-27 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AF_0285 4df1ff3c5f1c4c90772a09def80fce0f 658 SUPERFAMILY SSF51735 1 184 1.58E-66 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0285 4df1ff3c5f1c4c90772a09def80fce0f 658 Gene3D G3DSA:1.10.12.10 601 658 6.2E-16 T 31-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AF_0285 4df1ff3c5f1c4c90772a09def80fce0f 658 Pfam PF00378 Enoyl-CoA hydratase/isomerase 404 657 2.4E-66 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AF_0285 4df1ff3c5f1c4c90772a09def80fce0f 658 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 185 1.0E-71 T 31-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_2332 d0f46e0a15a91d56dd6ea20ff0dc4466 148 Gene3D G3DSA:3.40.50.360 1 146 9.8E-6 T 31-10-2018 IPR029039 Flavoprotein-like superfamily AF_2332 d0f46e0a15a91d56dd6ea20ff0dc4466 148 SUPERFAMILY SSF52218 1 143 2.62E-9 T 31-10-2018 IPR029039 Flavoprotein-like superfamily AF_0313 8a268324fdb971f490fced19053b547d 150 SMART SM00670 1 141 3.1E-26 T 31-10-2018 IPR002716 PIN domain AF_0313 8a268324fdb971f490fced19053b547d 150 SUPERFAMILY SSF88723 1 144 8.69E-21 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_0313 8a268324fdb971f490fced19053b547d 150 Gene3D G3DSA:3.40.50.1010 2 149 9.8E-15 T 31-10-2018 AF_0313 8a268324fdb971f490fced19053b547d 150 Pfam PF01850 PIN domain 3 145 2.0E-33 T 31-10-2018 IPR002716 PIN domain AF_2248 cc5ac273bba053cb5b95a2fd13cf1efc 77 Pfam PF13192 Thioredoxin domain 1 76 8.2E-24 T 31-10-2018 IPR012336 Thioredoxin-like fold AF_2248 cc5ac273bba053cb5b95a2fd13cf1efc 77 Gene3D G3DSA:3.40.30.10 1 75 2.6E-25 T 31-10-2018 AF_2248 cc5ac273bba053cb5b95a2fd13cf1efc 77 SUPERFAMILY SSF52833 1 76 6.81E-18 T 31-10-2018 IPR036249 Thioredoxin-like superfamily AF_2248 cc5ac273bba053cb5b95a2fd13cf1efc 77 PIRSF PIRSF037031 1 77 1.4E-30 T 31-10-2018 IPR005243 Redox-active disulphide protein 2 AF_2248 cc5ac273bba053cb5b95a2fd13cf1efc 77 TIGRFAM TIGR00412 redox_disulf_2: redox-active disulfide protein 2 1 77 5.3E-41 T 31-10-2018 IPR005243 Redox-active disulphide protein 2 AF_0587 c45d34ba4b6fca5adf90c565e5b7fffa 528 SUPERFAMILY SSF88697 465 525 8.7E-14 T 31-10-2018 IPR015947 PUA-like superfamily AF_0587 c45d34ba4b6fca5adf90c565e5b7fffa 528 SUPERFAMILY SSF88802 394 459 1.11E-29 T 31-10-2018 AF_0587 c45d34ba4b6fca5adf90c565e5b7fffa 528 Gene3D G3DSA:2.30.130.10 460 528 3.5E-31 T 31-10-2018 IPR036974 PUA domain superfamily GO:0003723 AF_0587 c45d34ba4b6fca5adf90c565e5b7fffa 528 Gene3D G3DSA:3.20.20.105 69 222 7.3E-16 T 31-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AF_0587 c45d34ba4b6fca5adf90c565e5b7fffa 528 Gene3D G3DSA:3.40.50.10630 230 394 2.8E-63 T 31-10-2018 AF_0587 c45d34ba4b6fca5adf90c565e5b7fffa 528 Pfam PF01472 PUA domain 472 524 7.1E-11 T 31-10-2018 IPR002478 PUA domain GO:0003723 AF_0587 c45d34ba4b6fca5adf90c565e5b7fffa 528 SUPERFAMILY SSF52141 245 390 7.85E-48 T 31-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AF_0587 c45d34ba4b6fca5adf90c565e5b7fffa 528 SMART SM00359 460 527 6.6E-9 T 31-10-2018 IPR002478 PUA domain GO:0003723 AF_0587 c45d34ba4b6fca5adf90c565e5b7fffa 528 Pfam PF01702 Queuine tRNA-ribosyltransferase 77 197 3.2E-6 T 31-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AF_0587 c45d34ba4b6fca5adf90c565e5b7fffa 528 SUPERFAMILY SSF51713 1 215 6.8E-27 T 31-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AF_0587 c45d34ba4b6fca5adf90c565e5b7fffa 528 Gene3D G3DSA:3.10.450.90 395 459 2.2E-38 T 31-10-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 AF_1125 e340050b5e84ffbadf2d874181080218 377 Pfam PF04055 Radical SAM superfamily 45 212 5.1E-18 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_1125 e340050b5e84ffbadf2d874181080218 377 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 288 352 2.6E-7 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain AF_1125 e340050b5e84ffbadf2d874181080218 377 PIRSF PIRSF037420 24 377 6.7E-128 T 31-10-2018 IPR017200 Coenzyme PQQ synthesis protein E AF_1125 e340050b5e84ffbadf2d874181080218 377 SUPERFAMILY SSF102114 41 351 1.12E-62 T 31-10-2018 AF_1125 e340050b5e84ffbadf2d874181080218 377 Pfam PF13186 Iron-sulfur cluster-binding domain 286 344 8.4E-7 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain AF_1125 e340050b5e84ffbadf2d874181080218 377 Gene3D G3DSA:3.20.20.70 38 350 1.4E-48 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1125 e340050b5e84ffbadf2d874181080218 377 Pfam PF13353 4Fe-4S single cluster domain 42 147 6.3E-11 T 31-10-2018 AF_1609 727e1fa1af8d774058d466b61423719a 575 SUPERFAMILY SSF55681 111 376 7.17E-80 T 31-10-2018 AF_1609 727e1fa1af8d774058d466b61423719a 575 Gene3D G3DSA:3.30.930.10 112 382 2.2E-87 T 31-10-2018 AF_1609 727e1fa1af8d774058d466b61423719a 575 Hamap MF_01571 Proline--tRNA ligase [proS]. 106 575 38.658 T 31-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 AF_1609 727e1fa1af8d774058d466b61423719a 575 SUPERFAMILY SSF52954 378 496 1.8E-27 T 31-10-2018 AF_1609 727e1fa1af8d774058d466b61423719a 575 SMART SM00946 499 575 6.7E-10 T 31-10-2018 IPR016061 Proline-tRNA ligase, class II, C-terminal GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 AF_1609 727e1fa1af8d774058d466b61423719a 575 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 202 372 1.3E-26 T 31-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_1609 727e1fa1af8d774058d466b61423719a 575 Gene3D G3DSA:3.40.50.800 384 500 1.8E-28 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily AF_1609 727e1fa1af8d774058d466b61423719a 575 TIGRFAM TIGR00408 proS_fam_I: proline--tRNA ligase 108 575 8.4E-209 T 31-10-2018 IPR004499 Proline-tRNA ligase, class IIa, archaeal-type GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 AF_1609 727e1fa1af8d774058d466b61423719a 575 Pfam PF03129 Anticodon binding domain 389 475 2.3E-17 T 31-10-2018 IPR004154 Anticodon-binding AF_1609 727e1fa1af8d774058d466b61423719a 575 SUPERFAMILY SSF64586 506 575 1.22E-9 T 31-10-2018 IPR017449 Prolyl-tRNA synthetase, class II GO:0000166|GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 AF_1609 727e1fa1af8d774058d466b61423719a 575 PRINTS PR01046 Prolyl-tRNA synthetase signature 205 216 7.5E-12 T 31-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AF_1609 727e1fa1af8d774058d466b61423719a 575 PRINTS PR01046 Prolyl-tRNA synthetase signature 245 256 7.5E-12 T 31-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AF_1609 727e1fa1af8d774058d466b61423719a 575 PRINTS PR01046 Prolyl-tRNA synthetase signature 164 182 7.5E-12 T 31-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AF_1609 727e1fa1af8d774058d466b61423719a 575 PRINTS PR01046 Prolyl-tRNA synthetase signature 235 243 7.5E-12 T 31-10-2018 IPR002316 Proline-tRNA ligase, class IIa GO:0004827|GO:0005524|GO:0005737|GO:0006433 KEGG: 00970+6.1.1.15|Reactome: R-HSA-379726 AF_1854 50165ec9661c70609b661b73d91083c2 474 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 3 199 1.2E-81 T 31-10-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 AF_1854 50165ec9661c70609b661b73d91083c2 474 Gene3D G3DSA:3.30.750.70 201 306 5.4E-37 T 31-10-2018 AF_1854 50165ec9661c70609b661b73d91083c2 474 Gene3D G3DSA:3.40.1080.10 1 193 1.1E-40 T 31-10-2018 AF_1854 50165ec9661c70609b661b73d91083c2 474 SUPERFAMILY SSF100950 4 237 4.79E-23 T 31-10-2018 IPR037171 NagB/RpiA transferase-like AF_1854 50165ec9661c70609b661b73d91083c2 474 SUPERFAMILY SSF100950 202 469 2.51E-57 T 31-10-2018 IPR037171 NagB/RpiA transferase-like AF_1854 50165ec9661c70609b661b73d91083c2 474 Gene3D G3DSA:3.40.1080.20 307 459 7.6E-49 T 31-10-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily AF_1854 50165ec9661c70609b661b73d91083c2 474 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 289 449 3.7E-55 T 31-10-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain AF_2148 cb0a7da2667d8a1f9fd557dcae3d85fd 290 SUPERFAMILY SSF56281 8 276 3.25E-35 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_2148 cb0a7da2667d8a1f9fd557dcae3d85fd 290 Gene3D G3DSA:3.60.15.10 1 225 2.2E-38 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_2148 cb0a7da2667d8a1f9fd557dcae3d85fd 290 SMART SM00849 17 198 1.9E-18 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_2148 cb0a7da2667d8a1f9fd557dcae3d85fd 290 Pfam PF00753 Metallo-beta-lactamase superfamily 15 198 6.3E-18 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_1806 8db5220d43ba7915de12ce7292a6437a 663 SMART SM00437 261 510 4.9E-98 T 31-10-2018 IPR003602 DNA topoisomerase, type IA, DNA-binding domain GO:0003677|GO:0003916|GO:0006265 AF_1806 8db5220d43ba7915de12ce7292a6437a 663 Pfam PF01751 Toprim domain 6 137 3.9E-16 T 31-10-2018 IPR006171 TOPRIM domain AF_1806 8db5220d43ba7915de12ce7292a6437a 663 SUPERFAMILY SSF56712 3 593 9.68E-153 T 31-10-2018 IPR023405 DNA topoisomerase, type IA, core domain AF_1806 8db5220d43ba7915de12ce7292a6437a 663 Gene3D G3DSA:3.40.50.140 1 152 1.4E-36 T 31-10-2018 AF_1806 8db5220d43ba7915de12ce7292a6437a 663 SMART SM00493 4 127 7.1E-32 T 31-10-2018 IPR006171 TOPRIM domain AF_1806 8db5220d43ba7915de12ce7292a6437a 663 Gene3D G3DSA:1.10.290.10 269 391 4.8E-115 T 31-10-2018 IPR013826 DNA topoisomerase, type IA, central region, subdomain 3 AF_1806 8db5220d43ba7915de12ce7292a6437a 663 Pfam PF01131 DNA topoisomerase 154 547 1.8E-123 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AF_1806 8db5220d43ba7915de12ce7292a6437a 663 ProSitePatterns PS00396 Prokaryotic DNA topoisomerase I active site. 296 310 - T 31-10-2018 IPR023406 DNA topoisomerase, type IA, active site GO:0003917 AF_1806 8db5220d43ba7915de12ce7292a6437a 663 Gene3D G3DSA:2.70.20.10 216 459 4.8E-115 T 31-10-2018 IPR013825 DNA topoisomerase, type IA, central region, subdomain 2 AF_1806 8db5220d43ba7915de12ce7292a6437a 663 SMART SM00436 130 222 6.9E-44 T 31-10-2018 IPR003601 DNA topoisomerase, type IA, domain 2 GO:0003677|GO:0003916|GO:0006265 AF_1806 8db5220d43ba7915de12ce7292a6437a 663 Hamap MF_00952 DNA topoisomerase 1 [topA]. 4 651 49.393 T 31-10-2018 IPR028612 DNA topoisomerase I, type IA GO:0003677|GO:0003916|GO:0006265 AF_1806 8db5220d43ba7915de12ce7292a6437a 663 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 101 114 1.4E-26 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AF_1806 8db5220d43ba7915de12ce7292a6437a 663 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 192 210 1.4E-26 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AF_1806 8db5220d43ba7915de12ce7292a6437a 663 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 377 393 1.4E-26 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AF_1806 8db5220d43ba7915de12ce7292a6437a 663 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 301 310 1.4E-26 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AF_1806 8db5220d43ba7915de12ce7292a6437a 663 PRINTS PR00417 Prokaryotic DNA topoisomerase I signature 475 489 1.4E-26 T 31-10-2018 IPR013497 DNA topoisomerase, type IA, central GO:0003677|GO:0003916|GO:0006265 AF_1806 8db5220d43ba7915de12ce7292a6437a 663 Pfam PF01396 Topoisomerase DNA binding C4 zinc finger 580 619 1.0E-17 T 31-10-2018 IPR013498 DNA topoisomerase, type IA, zn finger GO:0003677|GO:0003916|GO:0005694|GO:0006265 Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-6804756|Reactome: R-HSA-69473|Reactome: R-HSA-912446 AF_1806 8db5220d43ba7915de12ce7292a6437a 663 SUPERFAMILY SSF57783 582 619 8.33E-8 T 31-10-2018 AF_1806 8db5220d43ba7915de12ce7292a6437a 663 Gene3D G3DSA:1.10.460.10 161 558 4.8E-115 T 31-10-2018 IPR013824 DNA topoisomerase, type IA, central region, subdomain 1 AF_1337 748ad10842975cb00182504ba037b966 692 SUPERFAMILY SSF57938 2 73 1.31E-5 T 31-10-2018 IPR036410 Heat shock protein DnaJ, cysteine-rich domain superfamily AF_1337 748ad10842975cb00182504ba037b966 692 Gene3D G3DSA:2.40.50.140 181 283 4.2E-7 T 31-10-2018 AF_1337 748ad10842975cb00182504ba037b966 692 Pfam PF01336 OB-fold nucleic acid binding domain 207 277 2.1E-10 T 31-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AF_1337 748ad10842975cb00182504ba037b966 692 Gene3D G3DSA:2.40.50.140 114 180 8.2E-7 T 31-10-2018 AF_1337 748ad10842975cb00182504ba037b966 692 SMART SM00316 114 177 8.6E-9 T 31-10-2018 IPR022967 RNA-binding domain, S1 AF_1337 748ad10842975cb00182504ba037b966 692 SUPERFAMILY SSF50249 110 167 6.47E-8 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_1337 748ad10842975cb00182504ba037b966 692 Gene3D G3DSA:3.90.1640.30 311 504 2.3E-12 T 31-10-2018 AF_1337 748ad10842975cb00182504ba037b966 692 SUPERFAMILY SSF64182 315 690 2.09E-44 T 31-10-2018 IPR038763 DHH phosphoesterase superfamily AF_1337 748ad10842975cb00182504ba037b966 692 SUPERFAMILY SSF50249 205 273 4.21E-7 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_1337 748ad10842975cb00182504ba037b966 692 Pfam PF00575 S1 RNA binding domain 114 160 5.5E-5 T 31-10-2018 IPR003029 S1 domain GO:0003676 AF_1672 b3f36c904670fc3309feb9d4a154d1db 137 Pfam PF01842 ACT domain 70 128 2.2E-13 T 31-10-2018 IPR002912 ACT domain AF_1672 b3f36c904670fc3309feb9d4a154d1db 137 Pfam PF01842 ACT domain 4 60 1.8E-10 T 31-10-2018 IPR002912 ACT domain AF_1672 b3f36c904670fc3309feb9d4a154d1db 137 ProDom PD002844 SMALL SUBUNIT ACETOLACTATE SYNTHASE SYNTHASE TRANSFERASE ACID BIOSYNTHESIS III LYASE 1 71 0.001 T 31-10-2018 AF_1672 b3f36c904670fc3309feb9d4a154d1db 137 SUPERFAMILY SSF55021 1 68 1.07E-18 T 31-10-2018 AF_1672 b3f36c904670fc3309feb9d4a154d1db 137 SUPERFAMILY SSF55021 70 129 1.33E-15 T 31-10-2018 AF_1672 b3f36c904670fc3309feb9d4a154d1db 137 Gene3D G3DSA:3.30.2130.10 1 136 2.1E-56 T 31-10-2018 AF_2412 699143aabfc603e7851cd8cf4af43faf 425 Gene3D G3DSA:3.20.20.540 44 358 4.7E-141 T 31-10-2018 IPR038521 ThiC/Bza superfamily KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AF_2412 699143aabfc603e7851cd8cf4af43faf 425 TIGRFAM TIGR00190 thiC: phosphomethylpyrimidine synthase 1 422 2.7E-215 T 31-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AF_2412 699143aabfc603e7851cd8cf4af43faf 425 Pfam PF01964 Radical SAM ThiC family 2 419 4.9E-185 T 31-10-2018 IPR002817 Phosphomethylpyrimidine synthase ThiC/5-hydroxybenzimidazole synthase BzaA/B GO:0009228|GO:0051536 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AF_2412 699143aabfc603e7851cd8cf4af43faf 425 Hamap MF_00089 Phosphomethylpyrimidine synthase [thiC]. 1 424 84.68 T 31-10-2018 IPR037509 Phosphomethylpyrimidine synthase GO:0009228|GO:0016830 KEGG: 00730+4.1.99.17|MetaCyc: PWY-6890 AF_1273 2945f0d04cde413cecc349f1787d169d 358 SMART SM01097 1 131 3.3E-89 T 31-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_1273 2945f0d04cde413cecc349f1787d169d 358 Pfam PF00117 Glutamine amidotransferase class-I 176 352 1.5E-50 T 31-10-2018 IPR017926 Glutamine amidotransferase AF_1273 2945f0d04cde413cecc349f1787d169d 358 PRINTS PR00097 Anthranilate synthase component II signature 329 342 2.2E-5 T 31-10-2018 AF_1273 2945f0d04cde413cecc349f1787d169d 358 PRINTS PR00097 Anthranilate synthase component II signature 244 255 2.2E-5 T 31-10-2018 AF_1273 2945f0d04cde413cecc349f1787d169d 358 PRINTS PR00097 Anthranilate synthase component II signature 217 226 2.2E-5 T 31-10-2018 AF_1273 2945f0d04cde413cecc349f1787d169d 358 PRINTS PR00096 Glutamine amidotransferase superfamily signature 217 226 9.7E-11 T 31-10-2018 AF_1273 2945f0d04cde413cecc349f1787d169d 358 PRINTS PR00096 Glutamine amidotransferase superfamily signature 244 255 9.7E-11 T 31-10-2018 AF_1273 2945f0d04cde413cecc349f1787d169d 358 PRINTS PR00096 Glutamine amidotransferase superfamily signature 329 342 9.7E-11 T 31-10-2018 AF_1273 2945f0d04cde413cecc349f1787d169d 358 Gene3D G3DSA:3.40.50.880 149 358 3.9E-67 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_1273 2945f0d04cde413cecc349f1787d169d 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 286 297 1.3E-37 T 31-10-2018 AF_1273 2945f0d04cde413cecc349f1787d169d 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 175 189 1.3E-37 T 31-10-2018 AF_1273 2945f0d04cde413cecc349f1787d169d 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 244 260 1.3E-37 T 31-10-2018 AF_1273 2945f0d04cde413cecc349f1787d169d 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 214 228 1.3E-37 T 31-10-2018 AF_1273 2945f0d04cde413cecc349f1787d169d 358 PRINTS PR00099 Carbamoyl-phosphate synthase protein GATase domain signature 261 278 1.3E-37 T 31-10-2018 AF_1273 2945f0d04cde413cecc349f1787d169d 358 TIGRFAM TIGR01368 CPSaseIIsmall: carbamoyl-phosphate synthase, small subunit 3 355 1.2E-156 T 31-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_1273 2945f0d04cde413cecc349f1787d169d 358 Gene3D G3DSA:3.50.30.20 1 148 1.7E-58 T 31-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_1273 2945f0d04cde413cecc349f1787d169d 358 SUPERFAMILY SSF52021 1 143 1.7E-55 T 31-10-2018 IPR036480 Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_1273 2945f0d04cde413cecc349f1787d169d 358 Hamap MF_01209 Carbamoyl-phosphate synthase small chain [carA]. 1 358 48.962 T 31-10-2018 IPR006274 Carbamoyl-phosphate synthase, small subunit GO:0004088|GO:0006207|GO:0006541 KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_1273 2945f0d04cde413cecc349f1787d169d 358 Pfam PF00988 Carbamoyl-phosphate synthase small chain, CPSase domain 3 130 7.4E-53 T 31-10-2018 IPR002474 Carbamoyl-phosphate synthase small subunit, N-terminal domain KEGG: 00240+6.3.5.5|KEGG: 00250+6.3.5.5|MetaCyc: PWY-5154|MetaCyc: PWY-5686|MetaCyc: PWY-7400|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_1273 2945f0d04cde413cecc349f1787d169d 358 SUPERFAMILY SSF52317 152 357 3.85E-58 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_1329 291340abeaf7a12fc9ce1a879f619af8 233 SUPERFAMILY SSF51905 2 206 5.05E-13 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1329 291340abeaf7a12fc9ce1a879f619af8 233 Gene3D G3DSA:3.50.50.60 1 86 5.1E-5 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1329 291340abeaf7a12fc9ce1a879f619af8 233 Gene3D G3DSA:3.50.50.60 198 207 6.2E-7 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1329 291340abeaf7a12fc9ce1a879f619af8 233 Gene3D G3DSA:3.50.50.60 102 197 6.2E-7 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_2363 2f5f1013bad03f7edad53220ee410b8b 440 SUPERFAMILY SSF55326 59 220 3.29E-21 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AF_2363 2f5f1013bad03f7edad53220ee410b8b 440 Pfam PF00586 AIR synthase related protein, N-terminal domain 105 216 2.7E-9 T 31-10-2018 IPR016188 PurM-like, N-terminal domain AF_2363 2f5f1013bad03f7edad53220ee410b8b 440 SUPERFAMILY SSF56042 224 387 1.36E-22 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AF_2363 2f5f1013bad03f7edad53220ee410b8b 440 Gene3D G3DSA:3.90.650.10 224 396 1.6E-18 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AF_2363 2f5f1013bad03f7edad53220ee410b8b 440 Pfam PF02769 AIR synthase related protein, C-terminal domain 228 380 3.8E-17 T 31-10-2018 IPR010918 PurM-like, C-terminal domain AF_2363 2f5f1013bad03f7edad53220ee410b8b 440 PIRSF PIRSF006346 1 440 1.1E-219 T 31-10-2018 IPR009186 Predicted nickel metalloenzyme maturation factor, AIR synthase-related AF_2363 2f5f1013bad03f7edad53220ee410b8b 440 Gene3D G3DSA:3.30.1330.10 68 221 2.2E-17 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AF_1760 2d74e11ec071fb31edecaa09f70a2f8b 270 Gene3D G3DSA:3.40.50.620 142 270 7.2E-49 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_1760 2d74e11ec071fb31edecaa09f70a2f8b 270 PRINTS PR01438 Universal stress protein signature 243 265 1.0E-15 T 31-10-2018 IPR006015 Universal stress protein A AF_1760 2d74e11ec071fb31edecaa09f70a2f8b 270 PRINTS PR01438 Universal stress protein signature 146 164 1.0E-15 T 31-10-2018 IPR006015 Universal stress protein A AF_1760 2d74e11ec071fb31edecaa09f70a2f8b 270 PRINTS PR01438 Universal stress protein signature 225 237 1.0E-15 T 31-10-2018 IPR006015 Universal stress protein A AF_1760 2d74e11ec071fb31edecaa09f70a2f8b 270 Pfam PF00582 Universal stress protein family 1 137 2.9E-15 T 31-10-2018 IPR006016 UspA AF_1760 2d74e11ec071fb31edecaa09f70a2f8b 270 Pfam PF00582 Universal stress protein family 195 265 2.6E-15 T 31-10-2018 IPR006016 UspA AF_1760 2d74e11ec071fb31edecaa09f70a2f8b 270 Pfam PF00582 Universal stress protein family 146 191 9.7E-7 T 31-10-2018 IPR006016 UspA AF_1760 2d74e11ec071fb31edecaa09f70a2f8b 270 SUPERFAMILY SSF52402 2 139 3.93E-24 T 31-10-2018 AF_1760 2d74e11ec071fb31edecaa09f70a2f8b 270 SUPERFAMILY SSF52402 146 268 7.96E-30 T 31-10-2018 AF_1760 2d74e11ec071fb31edecaa09f70a2f8b 270 Gene3D G3DSA:3.40.50.620 1 141 6.2E-38 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_0533 f5cda22d7f1df5cd6e05e014b909c7da 206 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 192 3.9E-19 T 31-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 AF_0533 f5cda22d7f1df5cd6e05e014b909c7da 206 SUPERFAMILY SSF56300 1 204 1.97E-57 T 31-10-2018 AF_0533 f5cda22d7f1df5cd6e05e014b909c7da 206 Gene3D G3DSA:3.60.21.10 1 206 4.4E-24 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like AF_0373 211afc241e0eb2c9f28169674a2f90d0 183 Hamap MF_00408 TATA-box-binding protein [tbp]. 2 183 41.561 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 AF_0373 211afc241e0eb2c9f28169674a2f90d0 183 Gene3D G3DSA:3.30.310.10 8 173 3.3E-67 T 31-10-2018 IPR012295 TBP domain superfamily AF_0373 211afc241e0eb2c9f28169674a2f90d0 183 Gene3D G3DSA:3.30.310.10 13 99 3.3E-67 T 31-10-2018 IPR012295 TBP domain superfamily AF_0373 211afc241e0eb2c9f28169674a2f90d0 183 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 97 178 1.6E-30 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 AF_0373 211afc241e0eb2c9f28169674a2f90d0 183 Pfam PF00352 Transcription factor TFIID (or TATA-binding protein, TBP) 5 86 1.3E-29 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 AF_0373 211afc241e0eb2c9f28169674a2f90d0 183 PRINTS PR00686 Transcription initiation factor TFIID signature 51 69 3.8E-44 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 AF_0373 211afc241e0eb2c9f28169674a2f90d0 183 PRINTS PR00686 Transcription initiation factor TFIID signature 32 51 3.8E-44 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 AF_0373 211afc241e0eb2c9f28169674a2f90d0 183 PRINTS PR00686 Transcription initiation factor TFIID signature 8 23 3.8E-44 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 AF_0373 211afc241e0eb2c9f28169674a2f90d0 183 PRINTS PR00686 Transcription initiation factor TFIID signature 143 159 3.8E-44 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 AF_0373 211afc241e0eb2c9f28169674a2f90d0 183 PRINTS PR00686 Transcription initiation factor TFIID signature 124 139 3.8E-44 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 AF_0373 211afc241e0eb2c9f28169674a2f90d0 183 PRINTS PR00686 Transcription initiation factor TFIID signature 99 115 3.8E-44 T 31-10-2018 IPR000814 TATA-box binding protein GO:0003677|GO:0006352 AF_0373 211afc241e0eb2c9f28169674a2f90d0 183 SUPERFAMILY SSF55945 3 91 1.0E-29 T 31-10-2018 AF_0373 211afc241e0eb2c9f28169674a2f90d0 183 ProSitePatterns PS00351 Transcription factor TFIID repeat signature. 128 177 - T 31-10-2018 IPR030491 TATA-box binding protein, conserved site AF_0373 211afc241e0eb2c9f28169674a2f90d0 183 SUPERFAMILY SSF55945 92 181 1.13E-30 T 31-10-2018 AF_0906 ae73079d24017790fd861296865eee94 494 SUPERFAMILY SSF53067 1 393 5.1E-14 T 31-10-2018 AF_0906 ae73079d24017790fd861296865eee94 494 Pfam PF01968 Hydantoinase/oxoprolinase 164 345 6.2E-21 T 31-10-2018 IPR002821 Hydantoinase A/oxoprolinase GO:0016787 Reactome: R-HSA-174403|Reactome: R-HSA-5578998 AF_0906 ae73079d24017790fd861296865eee94 494 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 81 144 2.0E-4 T 31-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 AF_0906 ae73079d24017790fd861296865eee94 494 Pfam PF05378 Hydantoinase/oxoprolinase N-terminal region 3 42 2.7E-5 T 31-10-2018 IPR008040 Hydantoinaseoxoprolinase, N-terminal Reactome: R-HSA-174403|Reactome: R-HSA-5578998 AF_1028 009c97fe696341c0fdd7490b62c83cbc 396 PIRSF PIRSF000429 1 396 4.7E-121 T 31-10-2018 IPR002155 Thiolase GO:0016747 AF_1028 009c97fe696341c0fdd7490b62c83cbc 396 ProSitePatterns PS00099 Thiolases active site. 377 390 - T 31-10-2018 IPR020610 Thiolase, active site GO:0016747 AF_1028 009c97fe696341c0fdd7490b62c83cbc 396 Gene3D G3DSA:3.40.47.10 1 396 6.6E-127 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_1028 009c97fe696341c0fdd7490b62c83cbc 396 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 394 7.9E-122 T 31-10-2018 IPR002155 Thiolase GO:0016747 AF_1028 009c97fe696341c0fdd7490b62c83cbc 396 Pfam PF02803 Thiolase, C-terminal domain 274 395 5.3E-46 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 AF_1028 009c97fe696341c0fdd7490b62c83cbc 396 ProSitePatterns PS00737 Thiolases signature 2. 342 358 - T 31-10-2018 IPR020613 Thiolase, conserved site GO:0016747 AF_1028 009c97fe696341c0fdd7490b62c83cbc 396 SUPERFAMILY SSF53901 3 273 2.88E-56 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_1028 009c97fe696341c0fdd7490b62c83cbc 396 Pfam PF00108 Thiolase, N-terminal domain 4 265 1.6E-51 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AF_1028 009c97fe696341c0fdd7490b62c83cbc 396 SUPERFAMILY SSF53901 274 395 1.83E-44 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0522 146704a40f63e7770f814f7cf0c95227 316 Pfam PF01546 Peptidase family M20/M25/M40 51 311 4.1E-20 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 AF_0522 146704a40f63e7770f814f7cf0c95227 316 Pfam PF07687 Peptidase dimerisation domain 138 221 2.1E-17 T 31-10-2018 IPR011650 Peptidase M20, dimerisation domain AF_0522 146704a40f63e7770f814f7cf0c95227 316 Gene3D G3DSA:3.30.70.360 139 234 3.8E-57 T 31-10-2018 AF_0522 146704a40f63e7770f814f7cf0c95227 316 Gene3D G3DSA:3.40.630.10 2 306 3.8E-57 T 31-10-2018 AF_0522 146704a40f63e7770f814f7cf0c95227 316 SUPERFAMILY SSF55031 143 221 2.62E-13 T 31-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain AF_0522 146704a40f63e7770f814f7cf0c95227 316 SUPERFAMILY SSF53187 2 311 2.73E-36 T 31-10-2018 AF_1034 3c0c93123867665d7d2e2a914303e83e 677 Gene3D G3DSA:3.30.450.20 22 160 1.9E-16 T 31-10-2018 AF_1034 3c0c93123867665d7d2e2a914303e83e 677 SUPERFAMILY SSF58104 315 431 2.09E-9 T 31-10-2018 AF_1034 3c0c93123867665d7d2e2a914303e83e 677 SMART SM00086 117 157 420.0 T 31-10-2018 IPR001610 PAC motif AF_1034 3c0c93123867665d7d2e2a914303e83e 677 SMART SM00086 242 283 0.0079 T 31-10-2018 IPR001610 PAC motif AF_1034 3c0c93123867665d7d2e2a914303e83e 677 SMART SM00283 376 637 5.5E-78 T 31-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AF_1034 3c0c93123867665d7d2e2a914303e83e 677 Gene3D G3DSA:3.30.450.20 161 293 2.1E-20 T 31-10-2018 AF_1034 3c0c93123867665d7d2e2a914303e83e 677 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 47 163 1.1E-10 T 31-10-2018 IPR000014 PAS domain AF_1034 3c0c93123867665d7d2e2a914303e83e 677 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 183 289 3.1E-12 T 31-10-2018 IPR000014 PAS domain AF_1034 3c0c93123867665d7d2e2a914303e83e 677 SMART SM00304 295 347 6.9E-10 T 31-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AF_1034 3c0c93123867665d7d2e2a914303e83e 677 SMART SM00091 169 238 0.63 T 31-10-2018 IPR000014 PAS domain AF_1034 3c0c93123867665d7d2e2a914303e83e 677 SMART SM00091 35 105 0.27 T 31-10-2018 IPR000014 PAS domain AF_1034 3c0c93123867665d7d2e2a914303e83e 677 Gene3D G3DSA:1.10.287.950 325 652 9.9E-65 T 31-10-2018 AF_1034 3c0c93123867665d7d2e2a914303e83e 677 SUPERFAMILY SSF55785 22 155 1.92E-12 T 31-10-2018 IPR035965 PAS domain superfamily AF_1034 3c0c93123867665d7d2e2a914303e83e 677 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 448 603 1.6E-39 T 31-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AF_1034 3c0c93123867665d7d2e2a914303e83e 677 SUPERFAMILY SSF58104 409 641 5.36E-59 T 31-10-2018 AF_1034 3c0c93123867665d7d2e2a914303e83e 677 Pfam PF13426 PAS domain 184 282 5.2E-15 T 31-10-2018 IPR000014 PAS domain AF_1034 3c0c93123867665d7d2e2a914303e83e 677 Pfam PF13426 PAS domain 50 155 3.2E-9 T 31-10-2018 IPR000014 PAS domain AF_1034 3c0c93123867665d7d2e2a914303e83e 677 SUPERFAMILY SSF55785 154 281 3.49E-18 T 31-10-2018 IPR035965 PAS domain superfamily AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 Gene3D G3DSA:3.30.565.10 760 908 1.1E-37 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 SUPERFAMILY SSF55785 543 666 1.73E-24 T 31-10-2018 IPR035965 PAS domain superfamily AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 Pfam PF00512 His Kinase A (phospho-acceptor) domain 692 753 4.9E-10 T 31-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 Gene3D G3DSA:3.30.450.20 110 245 1.2E-15 T 31-10-2018 AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 SMART SM00065 263 406 8.2E-6 T 31-10-2018 IPR003018 GAF domain GO:0005515 AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 548 675 4.9E-33 T 31-10-2018 IPR000014 PAS domain AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 406 529 9.4E-29 T 31-10-2018 IPR000014 PAS domain AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 SUPERFAMILY SSF55874 745 905 1.01E-37 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 Pfam PF08447 PAS fold 432 503 1.3E-14 T 31-10-2018 IPR013655 PAS fold-3 GO:0005515 AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 PRINTS PR00344 Bacterial sensor protein C-terminal signature 893 906 6.2E-13 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 PRINTS PR00344 Bacterial sensor protein C-terminal signature 836 850 6.2E-13 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 PRINTS PR00344 Bacterial sensor protein C-terminal signature 869 887 6.2E-13 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 Gene3D G3DSA:3.30.450.20 553 680 2.5E-26 T 31-10-2018 AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 Gene3D G3DSA:3.30.450.20 415 552 6.1E-27 T 31-10-2018 AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 SMART SM00388 688 756 4.3E-11 T 31-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 SMART SM00387 797 908 5.1E-28 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 SUPERFAMILY SSF55785 114 232 8.9E-11 T 31-10-2018 IPR035965 PAS domain superfamily AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 Gene3D G3DSA:1.10.287.130 681 756 1.1E-12 T 31-10-2018 AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 SUPERFAMILY SSF55785 400 520 2.58E-26 T 31-10-2018 IPR035965 PAS domain superfamily AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 797 906 2.0E-21 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 SMART SM00091 410 475 4.5E-12 T 31-10-2018 IPR000014 PAS domain AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 SMART SM00091 125 192 0.011 T 31-10-2018 IPR000014 PAS domain AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 SMART SM00091 552 619 1.0E-9 T 31-10-2018 IPR000014 PAS domain AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 Pfam PF13426 PAS domain 137 233 4.9E-5 T 31-10-2018 IPR000014 PAS domain AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 Pfam PF13426 PAS domain 564 667 1.1E-14 T 31-10-2018 IPR000014 PAS domain AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 SUPERFAMILY SSF55781 264 409 1.72E-15 T 31-10-2018 AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 Gene3D G3DSA:3.30.450.40 249 409 1.9E-18 T 31-10-2018 IPR029016 GAF-like domain superfamily AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 SUPERFAMILY SSF47384 674 754 4.51E-16 T 31-10-2018 IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily GO:0000155|GO:0007165 AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 SMART SM00086 482 522 4.6 T 31-10-2018 IPR001610 PAC motif AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 SMART SM00086 626 668 1.4E-7 T 31-10-2018 IPR001610 PAC motif AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 Pfam PF13185 GAF domain 263 396 4.4E-7 T 31-10-2018 IPR003018 GAF domain GO:0005515 AF_1483 964e6264b9d59a54aa9edf0aa6667868 908 SUPERFAMILY SSF52172 17 121 2.78E-7 T 31-10-2018 IPR011006 CheY-like superfamily AF_0709 a357c0108a2c1710d37b2039f830376f 133 Gene3D G3DSA:2.160.10.10 6 131 7.4E-6 T 31-10-2018 AF_2034 4837b33a559042b4c73cf82e6dd8f4de 363 Gene3D G3DSA:3.40.350.10 1 133 1.6E-7 T 31-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal AF_2034 4837b33a559042b4c73cf82e6dd8f4de 363 SUPERFAMILY SSF55920 138 358 1.96E-43 T 31-10-2018 IPR036005 Creatinase/aminopeptidase-like AF_2034 4837b33a559042b4c73cf82e6dd8f4de 363 ProSitePatterns PS00491 Aminopeptidase P and proline dipeptidase signature. 294 306 - T 31-10-2018 IPR001131 Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site AF_2034 4837b33a559042b4c73cf82e6dd8f4de 363 Gene3D G3DSA:3.90.230.10 138 360 1.2E-50 T 31-10-2018 AF_2034 4837b33a559042b4c73cf82e6dd8f4de 363 Pfam PF00557 Metallopeptidase family M24 176 346 4.4E-39 T 31-10-2018 IPR000994 Peptidase M24 AF_2034 4837b33a559042b4c73cf82e6dd8f4de 363 Pfam PF01321 Creatinase/Prolidase N-terminal domain 3 122 1.1E-6 T 31-10-2018 IPR000587 Creatinase, N-terminal GO:0016787 AF_2034 4837b33a559042b4c73cf82e6dd8f4de 363 SUPERFAMILY SSF53092 3 119 4.53E-6 T 31-10-2018 IPR029149 Creatinase/Aminopeptidase P/Spt16, N-terminal AF_1324 738102621fe3c43f7415256ffc8473c6 505 Gene3D G3DSA:3.30.420.40 2 256 3.4E-59 T 31-10-2018 AF_1324 738102621fe3c43f7415256ffc8473c6 505 SUPERFAMILY SSF53067 258 497 2.36E-47 T 31-10-2018 AF_1324 738102621fe3c43f7415256ffc8473c6 505 PIRSF PIRSF000538 1 502 2.5E-99 T 31-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AF_1324 738102621fe3c43f7415256ffc8473c6 505 SUPERFAMILY SSF53067 4 259 6.39E-47 T 31-10-2018 AF_1324 738102621fe3c43f7415256ffc8473c6 505 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 269 450 1.5E-21 T 31-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 AF_1324 738102621fe3c43f7415256ffc8473c6 505 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 4 256 4.7E-40 T 31-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 AF_1324 738102621fe3c43f7415256ffc8473c6 505 Gene3D G3DSA:3.30.420.40 258 505 2.0E-58 T 31-10-2018 AF_1406 785b029c681efa3c3b7b809f298b3b43 775 Pfam PF04851 Type III restriction enzyme, res subunit 126 278 8.2E-17 T 31-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AF_1406 785b029c681efa3c3b7b809f298b3b43 775 Gene3D G3DSA:3.40.50.300 119 305 4.4E-13 T 31-10-2018 AF_1406 785b029c681efa3c3b7b809f298b3b43 775 SUPERFAMILY SSF52540 73 292 3.69E-16 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1406 785b029c681efa3c3b7b809f298b3b43 775 SMART SM00487 113 317 3.4E-8 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AF_0431 7f0a69d9ee477053bdf3e73ca7fa15b9 334 SUPERFAMILY SSF81345 4 331 1.31E-83 T 31-10-2018 IPR037294 ABC transporter, BtuC-like AF_0431 7f0a69d9ee477053bdf3e73ca7fa15b9 334 Pfam PF01032 FecCD transport family 18 331 9.5E-96 T 31-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AF_0431 7f0a69d9ee477053bdf3e73ca7fa15b9 334 Gene3D G3DSA:1.10.3470.10 1 333 4.8E-101 T 31-10-2018 IPR037294 ABC transporter, BtuC-like AF_1099 75c6caca914929b61b990a11368ad7bc 272 Pfam PF05681 Fumarate hydratase (Fumerase) 8 269 2.0E-99 T 31-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 AF_1099 75c6caca914929b61b990a11368ad7bc 272 TIGRFAM TIGR00722 ttdA_fumA_fumB: hydrolyase, tartrate alpha subunit/fumarate domain protein, Fe-S type 6 270 1.9E-128 T 31-10-2018 IPR004646 Fe-S hydro-lyase, tartrate dehydratase alpha-type, catalytic domain GO:0016829 AF_0987 6e46698a3e625b024f1d2a26a9eb468f 130 PRINTS PR01438 Universal stress protein signature 108 130 7.6E-7 T 31-10-2018 IPR006015 Universal stress protein A AF_0987 6e46698a3e625b024f1d2a26a9eb468f 130 PRINTS PR01438 Universal stress protein signature 90 102 7.6E-7 T 31-10-2018 IPR006015 Universal stress protein A AF_0987 6e46698a3e625b024f1d2a26a9eb468f 130 SUPERFAMILY SSF52402 3 130 1.42E-26 T 31-10-2018 AF_0987 6e46698a3e625b024f1d2a26a9eb468f 130 Pfam PF00582 Universal stress protein family 3 130 2.9E-26 T 31-10-2018 IPR006016 UspA AF_0987 6e46698a3e625b024f1d2a26a9eb468f 130 Gene3D G3DSA:3.40.50.620 1 130 5.4E-31 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_0598 6c91a77984aa55463752564c3b6c9f15 150 Pfam PF11848 Domain of unknown function (DUF3368) 102 147 1.9E-17 T 31-10-2018 IPR021799 Protein of unknown function DUF3368 AF_1807 f514c6bf9e858b2f5c1c5eaadf6abfaa 102 SUPERFAMILY SSF46785 31 99 2.14E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1807 f514c6bf9e858b2f5c1c5eaadf6abfaa 102 SMART SM00418 19 95 0.0024 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_1807 f514c6bf9e858b2f5c1c5eaadf6abfaa 102 Pfam PF01022 Bacterial regulatory protein, arsR family 28 72 1.6E-14 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_1807 f514c6bf9e858b2f5c1c5eaadf6abfaa 102 Gene3D G3DSA:1.10.10.10 1 92 6.1E-15 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1380 c2d2b9d52fe9b5ad9a60991fc4427625 569 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 557 566 - T 31-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 AF_1380 c2d2b9d52fe9b5ad9a60991fc4427625 569 Gene3D G3DSA:1.10.645.10 1 501 1.5E-137 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1380 c2d2b9d52fe9b5ad9a60991fc4427625 569 Pfam PF00374 Nickel-dependent hydrogenase 49 121 7.2E-27 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 AF_1380 c2d2b9d52fe9b5ad9a60991fc4427625 569 Pfam PF00374 Nickel-dependent hydrogenase 152 495 5.2E-68 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 AF_1380 c2d2b9d52fe9b5ad9a60991fc4427625 569 Gene3D G3DSA:1.10.645.10 531 569 1.5E-5 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1380 c2d2b9d52fe9b5ad9a60991fc4427625 569 SUPERFAMILY SSF56762 6 493 3.01E-114 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1435 e2fe77cd4bb138ab28713afbfeab6474 328 Pfam PF01137 RNA 3'-terminal phosphate cyclase 9 318 3.8E-84 T 31-10-2018 IPR023797 RNA 3'-terminal phosphate cyclase domain AF_1435 e2fe77cd4bb138ab28713afbfeab6474 328 Hamap MF_00200 RNA 3'-terminal phosphate cyclase [rtcA]. 1 328 40.946 T 31-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 AF_1435 e2fe77cd4bb138ab28713afbfeab6474 328 ProSitePatterns PS01287 RNA 3'-terminal phosphate cyclase signature. 154 164 - T 31-10-2018 IPR020719 RNA 3'-terminal phosphate cyclase-like, conserved site AF_1435 e2fe77cd4bb138ab28713afbfeab6474 328 Pfam PF05189 RNA 3'-terminal phosphate cyclase (RTC), insert domain 185 267 4.6E-16 T 31-10-2018 IPR013791 RNA 3'-terminal phosphate cyclase, insert domain AF_1435 e2fe77cd4bb138ab28713afbfeab6474 328 Gene3D G3DSA:3.30.360.20 178 268 3.0E-121 T 31-10-2018 IPR036553 RNA 3'-terminal phosphate cyclase, insert domain superfamily AF_1435 e2fe77cd4bb138ab28713afbfeab6474 328 TIGRFAM TIGR03399 RNA_3prim_cycl: RNA 3'-phosphate cyclase 2 318 2.6E-137 T 31-10-2018 IPR017770 RNA 3'-terminal phosphate cyclase type 1 GO:0003963|GO:0006396 AF_1435 e2fe77cd4bb138ab28713afbfeab6474 328 SUPERFAMILY SSF55205 1 224 7.19E-71 T 31-10-2018 IPR013792 RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta GO:0003824 AF_1435 e2fe77cd4bb138ab28713afbfeab6474 328 Gene3D G3DSA:3.65.10.20 3 315 3.0E-121 T 31-10-2018 IPR037136 RNA 3'-terminal phosphate cyclase domain superfamily AF_1435 e2fe77cd4bb138ab28713afbfeab6474 328 PIRSF PIRSF005378 1 326 3.1E-113 T 31-10-2018 IPR000228 RNA 3'-terminal phosphate cyclase GO:0006396 AF_1365 174c9bf98a01e098f860e1645cb852cf 344 SUPERFAMILY SSF56042 170 337 5.53E-39 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AF_1365 174c9bf98a01e098f860e1645cb852cf 344 Pfam PF00586 AIR synthase related protein, N-terminal domain 49 145 1.1E-12 T 31-10-2018 IPR016188 PurM-like, N-terminal domain AF_1365 174c9bf98a01e098f860e1645cb852cf 344 Pfam PF02769 AIR synthase related protein, C-terminal domain 175 317 1.7E-28 T 31-10-2018 IPR010918 PurM-like, C-terminal domain AF_1365 174c9bf98a01e098f860e1645cb852cf 344 Gene3D G3DSA:3.30.1330.10 5 151 2.1E-33 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AF_1365 174c9bf98a01e098f860e1645cb852cf 344 TIGRFAM TIGR02124 hypE: hydrogenase expression/formation protein HypE 8 344 1.0E-95 T 31-10-2018 IPR011854 Carbamoyl dehydratase HypE AF_1365 174c9bf98a01e098f860e1645cb852cf 344 SUPERFAMILY SSF55326 49 147 2.44E-20 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AF_1365 174c9bf98a01e098f860e1645cb852cf 344 Gene3D G3DSA:3.90.650.10 169 344 1.0E-49 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AF_1365 174c9bf98a01e098f860e1645cb852cf 344 PIRSF PIRSF005644 1 344 1.1E-120 T 31-10-2018 IPR011854 Carbamoyl dehydratase HypE AF_1450 af32e1662b788bf41b6a7886d27caf9d 302 Pfam PF13353 4Fe-4S single cluster domain 18 166 1.4E-13 T 31-10-2018 AF_1450 af32e1662b788bf41b6a7886d27caf9d 302 ProSitePatterns PS01087 Radical activating enzymes signature. 19 40 - T 31-10-2018 IPR001989 Radical-activating enzyme, conserved site GO:0016491|GO:0051539|GO:0055114 AF_1450 af32e1662b788bf41b6a7886d27caf9d 302 PIRSF PIRSF000371 1 300 3.1E-126 T 31-10-2018 IPR012839 Organic radical enzyme activase GO:0016491|GO:0055114 AF_1450 af32e1662b788bf41b6a7886d27caf9d 302 Gene3D G3DSA:3.30.70.20 79 123 5.0E-6 T 31-10-2018 AF_1450 af32e1662b788bf41b6a7886d27caf9d 302 Gene3D G3DSA:3.80.30.10 124 300 4.5E-55 T 31-10-2018 AF_1450 af32e1662b788bf41b6a7886d27caf9d 302 SUPERFAMILY SSF54862 6 147 7.6E-24 T 31-10-2018 AF_1450 af32e1662b788bf41b6a7886d27caf9d 302 TIGRFAM TIGR02494 PFLE_PFLC: glycyl-radical enzyme activating protein 8 292 5.6E-118 T 31-10-2018 AF_1450 af32e1662b788bf41b6a7886d27caf9d 302 Gene3D G3DSA:3.20.20.70 4 78 1.5E-18 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1450 af32e1662b788bf41b6a7886d27caf9d 302 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 85 96 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1450 af32e1662b788bf41b6a7886d27caf9d 302 Pfam PF04055 Radical SAM superfamily 26 234 8.4E-31 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_1450 af32e1662b788bf41b6a7886d27caf9d 302 SUPERFAMILY SSF102114 122 259 4.12E-19 T 31-10-2018 AF_0062 e9356c1e71443d01898fcbb0014c4bbb 296 SUPERFAMILY SSF54631 138 295 9.47E-23 T 31-10-2018 AF_0062 e9356c1e71443d01898fcbb0014c4bbb 296 Gene3D G3DSA:3.10.580.10 140 296 5.6E-20 T 31-10-2018 AF_0062 e9356c1e71443d01898fcbb0014c4bbb 296 Gene3D G3DSA:3.10.580.10 76 138 4.7E-16 T 31-10-2018 AF_0062 e9356c1e71443d01898fcbb0014c4bbb 296 SMART SM00116 27 74 7.8E-7 T 31-10-2018 IPR000644 CBS domain AF_0062 e9356c1e71443d01898fcbb0014c4bbb 296 SMART SM00116 85 132 2.2E-14 T 31-10-2018 IPR000644 CBS domain AF_0062 e9356c1e71443d01898fcbb0014c4bbb 296 SMART SM00116 246 294 9.9E-5 T 31-10-2018 IPR000644 CBS domain AF_0062 e9356c1e71443d01898fcbb0014c4bbb 296 SUPERFAMILY SSF54631 14 134 1.52E-32 T 31-10-2018 AF_0062 e9356c1e71443d01898fcbb0014c4bbb 296 Pfam PF00571 CBS domain 81 132 4.0E-15 T 31-10-2018 IPR000644 CBS domain AF_0062 e9356c1e71443d01898fcbb0014c4bbb 296 Pfam PF00571 CBS domain 140 187 0.0024 T 31-10-2018 IPR000644 CBS domain AF_0062 e9356c1e71443d01898fcbb0014c4bbb 296 Pfam PF00571 CBS domain 21 74 7.0E-12 T 31-10-2018 IPR000644 CBS domain AF_0062 e9356c1e71443d01898fcbb0014c4bbb 296 Pfam PF00571 CBS domain 240 294 4.5E-10 T 31-10-2018 IPR000644 CBS domain AF_0062 e9356c1e71443d01898fcbb0014c4bbb 296 Gene3D G3DSA:3.10.580.10 4 75 1.1E-12 T 31-10-2018 AF_0895 628656ee7b273edb752ffc81265e9d5d 93 Pfam PF13610 DDE domain 1 63 3.3E-10 T 31-10-2018 IPR032874 DDE domain AF_0006 b7572390e23e8f289262464fa0f91a26 210 SMART SM01018 2 84 7.2E-24 T 31-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AF_0006 b7572390e23e8f289262464fa0f91a26 210 SUPERFAMILY SSF52242 70 208 4.71E-41 T 31-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 AF_0006 b7572390e23e8f289262464fa0f91a26 210 Pfam PF02607 B12 binding domain 5 76 8.3E-13 T 31-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AF_0006 b7572390e23e8f289262464fa0f91a26 210 SUPERFAMILY SSF47644 4 83 1.14E-16 T 31-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AF_0006 b7572390e23e8f289262464fa0f91a26 210 Gene3D G3DSA:3.40.50.280 79 209 2.6E-44 T 31-10-2018 AF_0006 b7572390e23e8f289262464fa0f91a26 210 Pfam PF02310 B12 binding domain 90 196 2.7E-26 T 31-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AF_0006 b7572390e23e8f289262464fa0f91a26 210 Gene3D G3DSA:1.10.1240.10 3 78 5.5E-24 T 31-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AF_1803 444ac52ed4b3ea987f958dacd856c7c1 310 PIRSF PIRSF004967 5 310 2.4E-72 T 31-10-2018 IPR035435 Diphthamide synthesis DHP1/DPH2, eukaryotes and archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 AF_1803 444ac52ed4b3ea987f958dacd856c7c1 310 TIGRFAM TIGR00322 diphth2_R: diphthamide biosynthesis enzyme Dph1/Dph2 domain 12 297 3.3E-78 T 31-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 AF_1803 444ac52ed4b3ea987f958dacd856c7c1 310 Gene3D G3DSA:3.40.50.11860 197 297 4.2E-28 T 31-10-2018 AF_1803 444ac52ed4b3ea987f958dacd856c7c1 310 TIGRFAM TIGR03682 arCOG04112: diphthamide biosynthesis enzyme Dph2 13 308 2.2E-108 T 31-10-2018 IPR022428 Diphthamide synthesis Dph2, archaea GO:0017183 MetaCyc: PWY-6482|MetaCyc: PWY-7546 AF_1803 444ac52ed4b3ea987f958dacd856c7c1 310 Pfam PF01866 Putative diphthamide synthesis protein 21 301 3.2E-69 T 31-10-2018 IPR016435 Diphthamide synthesis DPH1/DPH2 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 AF_1803 444ac52ed4b3ea987f958dacd856c7c1 310 Gene3D G3DSA:3.40.50.11850 91 193 3.5E-31 T 31-10-2018 AF_1803 444ac52ed4b3ea987f958dacd856c7c1 310 Gene3D G3DSA:3.40.50.11840 7 90 2.4E-18 T 31-10-2018 AF_0731 8a43079ba5c27cfc90363f6f692022db 326 TIGRFAM TIGR01166 cbiO: cobalt ABC transporter, ATP-binding protein 46 232 1.2E-90 T 31-10-2018 IPR005876 Cobalt transport protein ATP-binding subunit GO:0006824 AF_0731 8a43079ba5c27cfc90363f6f692022db 326 SMART SM00382 59 246 4.2E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0731 8a43079ba5c27cfc90363f6f692022db 326 ProSitePatterns PS00211 ABC transporters family signature. 170 184 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_0731 8a43079ba5c27cfc90363f6f692022db 326 SUPERFAMILY SSF52540 35 251 2.77E-60 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0731 8a43079ba5c27cfc90363f6f692022db 326 Pfam PF00005 ABC transporter 50 198 2.9E-31 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0731 8a43079ba5c27cfc90363f6f692022db 326 Gene3D G3DSA:3.40.50.300 31 268 7.8E-66 T 31-10-2018 AF_1371 1843d71de5ebeec569e0b4cf79767ac3 130 Pfam PF01750 Hydrogenase maturation protease 35 109 7.1E-5 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AF_1371 1843d71de5ebeec569e0b4cf79767ac3 130 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 1 107 2.2E-13 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AF_1371 1843d71de5ebeec569e0b4cf79767ac3 130 SUPERFAMILY SSF53163 1 110 2.88E-16 T 31-10-2018 IPR023430 Peptidase HybD-like domain superfamily AF_1371 1843d71de5ebeec569e0b4cf79767ac3 130 Gene3D G3DSA:3.40.50.1450 1 126 1.0E-14 T 31-10-2018 IPR023430 Peptidase HybD-like domain superfamily AF_1903 d0c713061dccc0d8a771b60af5b85b20 179 Pfam PF00828 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A 29 177 5.2E-22 T 31-10-2018 IPR021131 Ribosomal protein L18e/L15P AF_1903 d0c713061dccc0d8a771b60af5b85b20 179 Hamap MF_01341 50S ribosomal protein L15 [rplO]. 2 179 13.284 T 31-10-2018 IPR030878 Ribosomal protein L15 GO:0003735|GO:0006412|GO:0015934 AF_1903 d0c713061dccc0d8a771b60af5b85b20 179 SUPERFAMILY SSF52080 6 78 4.14E-11 T 31-10-2018 IPR036227 Ribosomal L18e/L15P superfamily AF_1903 d0c713061dccc0d8a771b60af5b85b20 179 Gene3D G3DSA:4.10.990.10 5 55 7.9E-22 T 31-10-2018 IPR027386 50S ribosomal protein L15, N-terminal AF_1903 d0c713061dccc0d8a771b60af5b85b20 179 ProSitePatterns PS00475 Ribosomal protein L15 signature. 143 173 - T 31-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1903 d0c713061dccc0d8a771b60af5b85b20 179 SUPERFAMILY SSF52080 102 177 7.06E-17 T 31-10-2018 IPR036227 Ribosomal L18e/L15P superfamily AF_1903 d0c713061dccc0d8a771b60af5b85b20 179 Gene3D G3DSA:3.100.10.10 99 179 3.0E-19 T 31-10-2018 AF_2360 b66fd357835e453c6f69af3a1eea9ef6 134 SMART SM00670 1 123 6.8E-20 T 31-10-2018 IPR002716 PIN domain AF_2360 b66fd357835e453c6f69af3a1eea9ef6 134 Pfam PF01850 PIN domain 4 125 1.4E-17 T 31-10-2018 IPR002716 PIN domain AF_2360 b66fd357835e453c6f69af3a1eea9ef6 134 Gene3D G3DSA:3.40.50.1010 1 134 2.3E-18 T 31-10-2018 AF_2360 b66fd357835e453c6f69af3a1eea9ef6 134 SUPERFAMILY SSF88723 1 133 1.63E-22 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_0260 643f19c5689e27278939949935c9b202 551 TIGRFAM TIGR00463 gltX_arch: glutamate--tRNA ligase 1 551 1.1E-270 T 31-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 AF_0260 643f19c5689e27278939949935c9b202 551 Gene3D G3DSA:3.40.50.620 56 404 3.2E-108 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_0260 643f19c5689e27278939949935c9b202 551 SUPERFAMILY SSF52374 93 408 1.45E-83 T 31-10-2018 AF_0260 643f19c5689e27278939949935c9b202 551 Gene3D G3DSA:2.40.240.10 412 499 1.4E-34 T 31-10-2018 IPR020056 Ribosomal protein L25/Gln-tRNA synthetase, N-terminal Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AF_0260 643f19c5689e27278939949935c9b202 551 Pfam PF00749 tRNA synthetases class I (E and Q), catalytic domain 93 399 1.4E-74 T 31-10-2018 IPR020058 Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain GO:0004812|GO:0005524|GO:0043039 AF_0260 643f19c5689e27278939949935c9b202 551 Gene3D G3DSA:2.40.240.100 405 550 1.4E-34 T 31-10-2018 AF_0260 643f19c5689e27278939949935c9b202 551 Pfam PF03950 tRNA synthetases class I (E and Q), anti-codon binding domain 403 537 1.6E-21 T 31-10-2018 IPR020059 Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0006418 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AF_0260 643f19c5689e27278939949935c9b202 551 Hamap MF_02076 Glutamate--tRNA ligase [gltX]. 5 549 36.558 T 31-10-2018 IPR004526 Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic GO:0000166|GO:0004818|GO:0005524|GO:0005737|GO:0006424 KEGG: 00860+6.1.1.17|KEGG: 00970+6.1.1.17|MetaCyc: PWY-5188|Reactome: R-HSA-2408517|Reactome: R-HSA-379716|Reactome: R-HSA-6782315 AF_0260 643f19c5689e27278939949935c9b202 551 PRINTS PR00987 Glutamyl-tRNA synthetase signature 126 139 2.6E-14 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AF_0260 643f19c5689e27278939949935c9b202 551 PRINTS PR00987 Glutamyl-tRNA synthetase signature 111 122 2.6E-14 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AF_0260 643f19c5689e27278939949935c9b202 551 PRINTS PR00987 Glutamyl-tRNA synthetase signature 289 297 2.6E-14 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AF_0260 643f19c5689e27278939949935c9b202 551 PRINTS PR00987 Glutamyl-tRNA synthetase signature 273 283 2.6E-14 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AF_0260 643f19c5689e27278939949935c9b202 551 PRINTS PR00987 Glutamyl-tRNA synthetase signature 97 109 2.6E-14 T 31-10-2018 IPR000924 Glutamyl/glutaminyl-tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0005737|GO:0043039 AF_0260 643f19c5689e27278939949935c9b202 551 SUPERFAMILY SSF50715 403 541 1.62E-17 T 31-10-2018 IPR011035 Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily GO:0006412 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AF_0700 f328f56e258b630b6ab5b4f72680905e 462 Gene3D G3DSA:3.30.2130.10 385 461 1.2E-25 T 31-10-2018 AF_0700 f328f56e258b630b6ab5b4f72680905e 462 Pfam PF01842 ACT domain 404 455 5.0E-10 T 31-10-2018 IPR002912 ACT domain AF_0700 f328f56e258b630b6ab5b4f72680905e 462 Pfam PF01842 ACT domain 335 383 3.5E-8 T 31-10-2018 IPR002912 ACT domain AF_0700 f328f56e258b630b6ab5b4f72680905e 462 Pfam PF00696 Amino acid kinase family 1 290 2.3E-56 T 31-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AF_0700 f328f56e258b630b6ab5b4f72680905e 462 Gene3D G3DSA:3.30.70.260 306 384 3.5E-12 T 31-10-2018 AF_0700 f328f56e258b630b6ab5b4f72680905e 462 SUPERFAMILY SSF55021 389 461 3.05E-24 T 31-10-2018 AF_0700 f328f56e258b630b6ab5b4f72680905e 462 SUPERFAMILY SSF53633 2 303 1.2E-86 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AF_0700 f328f56e258b630b6ab5b4f72680905e 462 TIGRFAM TIGR00657 asp_kinases: aspartate kinase 1 459 1.1E-162 T 31-10-2018 IPR001341 Aspartate kinase GO:0004072|GO:0008652 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AF_0700 f328f56e258b630b6ab5b4f72680905e 462 Gene3D G3DSA:3.40.1160.10 1 303 5.0E-108 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AF_0700 f328f56e258b630b6ab5b4f72680905e 462 TIGRFAM TIGR00656 asp_kin_monofn: aspartate kinase, monofunctional class 3 458 4.4E-130 T 31-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AF_0700 f328f56e258b630b6ab5b4f72680905e 462 SUPERFAMILY SSF55021 311 382 6.36E-14 T 31-10-2018 AF_0700 f328f56e258b630b6ab5b4f72680905e 462 PIRSF PIRSF000726 1 462 9.5E-130 T 31-10-2018 IPR005260 Aspartate kinase, monofunctional class GO:0004072|GO:0009089 KEGG: 00260+2.7.2.4|KEGG: 00261+2.7.2.4|KEGG: 00270+2.7.2.4|KEGG: 00300+2.7.2.4|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AF_0672 0d30cc9236d9bda0374ec392148d5c80 504 Pfam PF13193 AMP-binding enzyme C-terminal domain 412 491 7.0E-14 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AF_0672 0d30cc9236d9bda0374ec392148d5c80 504 Gene3D G3DSA:3.30.300.310 398 503 4.5E-25 T 31-10-2018 AF_0672 0d30cc9236d9bda0374ec392148d5c80 504 Gene3D G3DSA:3.40.50.12780 6 397 6.4E-86 T 31-10-2018 AF_0672 0d30cc9236d9bda0374ec392148d5c80 504 ProSitePatterns PS00455 Putative AMP-binding domain signature. 154 165 - T 31-10-2018 IPR020845 AMP-binding, conserved site AF_0672 0d30cc9236d9bda0374ec392148d5c80 504 SUPERFAMILY SSF56801 5 503 1.31E-114 T 31-10-2018 AF_0672 0d30cc9236d9bda0374ec392148d5c80 504 Pfam PF00501 AMP-binding enzyme 18 402 1.4E-76 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_2284 b37e25e1339866389dfd0f978f7fdba9 172 Gene3D G3DSA:3.10.290.10 108 170 4.7E-18 T 31-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AF_2284 b37e25e1339866389dfd0f978f7fdba9 172 Pfam PF01479 S4 domain 109 153 5.7E-17 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2284 b37e25e1339866389dfd0f978f7fdba9 172 TIGRFAM TIGR01018 uS4_arch: ribosomal protein uS4 1 166 3.5E-79 T 31-10-2018 IPR005710 Ribosomal protein S4/S9, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2284 b37e25e1339866389dfd0f978f7fdba9 172 Hamap MF_01306_A 30S ribosomal protein S4 [rpsD]. 1 162 35.211 T 31-10-2018 IPR022802 Ribosomal protein S4, archaeal GO:0006412|GO:0019843 AF_2284 b37e25e1339866389dfd0f978f7fdba9 172 SMART SM00363 109 171 4.3E-12 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2284 b37e25e1339866389dfd0f978f7fdba9 172 SUPERFAMILY SSF55174 9 166 5.89E-33 T 31-10-2018 AF_2284 b37e25e1339866389dfd0f978f7fdba9 172 ProSitePatterns PS00632 Ribosomal protein S4 signature. 107 131 - T 31-10-2018 IPR018079 Ribosomal protein S4, conserved site GO:0005622|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2284 b37e25e1339866389dfd0f978f7fdba9 172 SMART SM01390 5 108 4.1E-13 T 31-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 AF_2284 b37e25e1339866389dfd0f978f7fdba9 172 Pfam PF00163 Ribosomal protein S4/S9 N-terminal domain 4 60 1.6E-6 T 31-10-2018 IPR001912 Ribosomal protein S4/S9, N-terminal GO:0005622|GO:0019843 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 AF_2321 db047dda9209839545fd17e8efe64459 181 SUPERFAMILY SSF53448 2 176 5.01E-17 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_2321 db047dda9209839545fd17e8efe64459 181 TIGRFAM TIGR00454 TIGR00454: TIGR00454 family protein 1 168 5.3E-76 T 31-10-2018 IPR005245 Conserved hypothetical protein CHP00454 KEGG: 00860+2.7.7.62|MetaCyc: PWY-6269|MetaCyc: PWY-7962|MetaCyc: PWY-7971|MetaCyc: PWY-7972 AF_2321 db047dda9209839545fd17e8efe64459 181 Pfam PF12804 MobA-like NTP transferase domain 4 101 2.2E-11 T 31-10-2018 IPR025877 MobA-like NTP transferase AF_2321 db047dda9209839545fd17e8efe64459 181 Gene3D G3DSA:3.90.550.10 3 171 2.1E-27 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_1023 f7e9b823f1703b5391ad49742689b8b2 364 Gene3D G3DSA:3.30.9.10 67 323 2.9E-62 T 31-10-2018 AF_1023 f7e9b823f1703b5391ad49742689b8b2 364 SUPERFAMILY SSF51905 2 324 4.31E-27 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1023 f7e9b823f1703b5391ad49742689b8b2 364 Pfam PF13450 NAD(P)-binding Rossmann-like domain 5 36 1.2E-4 T 31-10-2018 AF_1023 f7e9b823f1703b5391ad49742689b8b2 364 Gene3D G3DSA:3.50.50.60 2 307 2.9E-62 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1023 f7e9b823f1703b5391ad49742689b8b2 364 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 4.1E-11 T 31-10-2018 AF_1023 f7e9b823f1703b5391ad49742689b8b2 364 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 129 144 4.1E-11 T 31-10-2018 AF_1023 f7e9b823f1703b5391ad49742689b8b2 364 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 244 259 4.1E-11 T 31-10-2018 AF_1023 f7e9b823f1703b5391ad49742689b8b2 364 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 2 273 1.4E-47 T 31-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 AF_0115 84f5d2f81a2e7ad961d98240b0217325 257 Gene3D G3DSA:3.60.110.10 1 257 5.2E-79 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AF_0115 84f5d2f81a2e7ad961d98240b0217325 257 SUPERFAMILY SSF56317 4 253 1.15E-72 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AF_0115 84f5d2f81a2e7ad961d98240b0217325 257 Pfam PF00795 Carbon-nitrogen hydrolase 8 244 4.4E-62 T 31-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 AF_1252 b352f099c84c785e26baaafb4754a4c8 458 TIGRFAM TIGR01108 oadA: oxaloacetate decarboxylase alpha subunit 1 457 3.2E-236 T 31-10-2018 IPR005776 Oxaloacetate decarboxylase, alpha subunit GO:0006814|GO:0008948 AF_1252 b352f099c84c785e26baaafb4754a4c8 458 SUPERFAMILY SSF89000 276 425 7.85E-54 T 31-10-2018 AF_1252 b352f099c84c785e26baaafb4754a4c8 458 Pfam PF00682 HMGL-like 1 247 8.3E-40 T 31-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AF_1252 b352f099c84c785e26baaafb4754a4c8 458 SUPERFAMILY SSF51569 1 279 3.48E-81 T 31-10-2018 AF_1252 b352f099c84c785e26baaafb4754a4c8 458 Gene3D G3DSA:3.20.20.70 1 432 1.3E-160 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1252 b352f099c84c785e26baaafb4754a4c8 458 Pfam PF02436 Conserved carboxylase domain 271 452 1.3E-57 T 31-10-2018 IPR003379 Carboxylase, conserved domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599|Reactome: R-HSA-70263 AF_0450 fc1f51c5589cb2bd2f251088f209afe1 329 Pfam PF00989 PAS fold 8 110 2.9E-15 T 31-10-2018 IPR013767 PAS fold GO:0006355 AF_0450 fc1f51c5589cb2bd2f251088f209afe1 329 SUPERFAMILY SSF55874 191 323 6.94E-28 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_0450 fc1f51c5589cb2bd2f251088f209afe1 329 Gene3D G3DSA:3.30.565.10 188 323 8.4E-31 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_0450 fc1f51c5589cb2bd2f251088f209afe1 329 SMART SM00091 6 72 5.3E-12 T 31-10-2018 IPR000014 PAS domain AF_0450 fc1f51c5589cb2bd2f251088f209afe1 329 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 5 121 2.3E-20 T 31-10-2018 IPR000014 PAS domain AF_0450 fc1f51c5589cb2bd2f251088f209afe1 329 Gene3D G3DSA:3.30.450.20 3 127 1.9E-18 T 31-10-2018 AF_0450 fc1f51c5589cb2bd2f251088f209afe1 329 Gene3D G3DSA:1.10.287.130 132 186 8.4E-31 T 31-10-2018 AF_0450 fc1f51c5589cb2bd2f251088f209afe1 329 SUPERFAMILY SSF55785 8 111 9.99E-21 T 31-10-2018 IPR035965 PAS domain superfamily AF_0450 fc1f51c5589cb2bd2f251088f209afe1 329 PRINTS PR00344 Bacterial sensor protein C-terminal signature 287 305 1.1E-7 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_0450 fc1f51c5589cb2bd2f251088f209afe1 329 PRINTS PR00344 Bacterial sensor protein C-terminal signature 257 271 1.1E-7 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_0450 fc1f51c5589cb2bd2f251088f209afe1 329 PRINTS PR00344 Bacterial sensor protein C-terminal signature 311 324 1.1E-7 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_0450 fc1f51c5589cb2bd2f251088f209afe1 329 SMART SM00387 221 327 5.7E-28 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_0450 fc1f51c5589cb2bd2f251088f209afe1 329 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 224 324 4.4E-19 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_1595 da36c12b2c492f134bc0555cb82125f5 304 Pfam PF01171 PP-loop family 51 239 1.8E-10 T 31-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 AF_1595 da36c12b2c492f134bc0555cb82125f5 304 TIGRFAM TIGR00269 TIGR00269: TIGR00269 family protein 197 300 8.1E-49 T 31-10-2018 IPR000541 Cytoplasmic tRNA 2-thiolation protein 1 GO:0000049|GO:0002098|GO:0034227 Reactome: R-HSA-6782315 AF_1595 da36c12b2c492f134bc0555cb82125f5 304 SUPERFAMILY SSF52402 26 250 5.29E-51 T 31-10-2018 AF_1595 da36c12b2c492f134bc0555cb82125f5 304 PIRSF PIRSF004976 1 304 1.0E-107 T 31-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 AF_1595 da36c12b2c492f134bc0555cb82125f5 304 Gene3D G3DSA:3.40.50.620 2 304 1.1E-80 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_1595 da36c12b2c492f134bc0555cb82125f5 304 ProSitePatterns PS01263 Uncharacterized protein family UPF0021 signature. 23 60 - T 31-10-2018 IPR020554 Uncharacterised protein family UPF0021, conserved site AF_0839 2d6769ee46eaf919a3dfe1778305dbef 478 PIRSF PIRSF006247 1 476 4.7E-177 T 31-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 AF_0839 2d6769ee46eaf919a3dfe1778305dbef 478 TIGRFAM TIGR00933 2a38: potassium uptake protein, TrkH family 85 459 3.1E-116 T 31-10-2018 IPR004772 TrkH potassium transport family GO:0015379|GO:0016021|GO:0071805 AF_0839 2d6769ee46eaf919a3dfe1778305dbef 478 Pfam PF02386 Cation transport protein 45 470 5.7E-63 T 31-10-2018 IPR003445 Cation transporter GO:0006812|GO:0008324|GO:0055085 AF_0766 b5dc6a1a4abcb677ae5f88f5cb7e8097 58 SMART SM00746 6 44 3.3E-14 T 31-10-2018 IPR011017 TRASH domain AF_0766 b5dc6a1a4abcb677ae5f88f5cb7e8097 58 Gene3D G3DSA:2.30.170.20 4 57 1.7E-27 T 31-10-2018 IPR038630 Ribosomal protein L24e/L24 superfamily AF_0766 b5dc6a1a4abcb677ae5f88f5cb7e8097 58 Pfam PF01246 Ribosomal protein L24e 1 57 9.8E-26 T 31-10-2018 IPR000988 Ribosomal protein L24e-related AF_0766 b5dc6a1a4abcb677ae5f88f5cb7e8097 58 Hamap MF_00773 50S ribosomal protein L24e [rpl24e]. 1 55 28.597 T 31-10-2018 IPR023438 Ribosomal protein L24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_0766 b5dc6a1a4abcb677ae5f88f5cb7e8097 58 SUPERFAMILY SSF57716 4 56 7.98E-21 T 31-10-2018 AF_0766 b5dc6a1a4abcb677ae5f88f5cb7e8097 58 ProSitePatterns PS01073 Ribosomal protein L24e signature. 8 25 - T 31-10-2018 IPR023442 Ribosomal protein L24e, conserved site AF_2429 c6f8852972518d80b436fce6c471f08c 243 SUPERFAMILY SSF52096 4 232 3.22E-60 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AF_2429 c6f8852972518d80b436fce6c471f08c 243 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 229 2.7E-44 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AF_2429 c6f8852972518d80b436fce6c471f08c 243 Gene3D G3DSA:3.90.226.10 3 242 3.8E-64 T 31-10-2018 AF_2104 46a30dc83e50969e0341d69bfff47ef7 379 Gene3D G3DSA:3.20.20.70 1 325 1.6E-20 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_2104 46a30dc83e50969e0341d69bfff47ef7 379 Pfam PF04055 Radical SAM superfamily 8 127 4.0E-11 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_2104 46a30dc83e50969e0341d69bfff47ef7 379 SUPERFAMILY SSF102114 5 347 1.04E-23 T 31-10-2018 AF_0161 0f6e66e646f199125b4e6e9742c1af79 400 ProSitePatterns PS01079 Molybdenum cofactor biosynthesis proteins signature 2. 248 281 - T 31-10-2018 IPR008284 Molybdenum cofactor biosynthesis, conserved site GO:0006777 Reactome: R-HSA-947581 AF_0161 0f6e66e646f199125b4e6e9742c1af79 400 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 179 303 2.2E-36 T 31-10-2018 IPR001453 MoaB/Mog domain AF_0161 0f6e66e646f199125b4e6e9742c1af79 400 Pfam PF03453 MoeA N-terminal region (domain I and II) 23 169 4.6E-38 T 31-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AF_0161 0f6e66e646f199125b4e6e9742c1af79 400 SMART SM00852 182 312 3.6E-31 T 31-10-2018 IPR001453 MoaB/Mog domain AF_0161 0f6e66e646f199125b4e6e9742c1af79 400 Gene3D G3DSA:3.40.980.10 29 305 3.6E-92 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily AF_0161 0f6e66e646f199125b4e6e9742c1af79 400 Gene3D G3DSA:2.170.190.11 54 143 3.6E-92 T 31-10-2018 AF_0161 0f6e66e646f199125b4e6e9742c1af79 400 SUPERFAMILY SSF63882 5 178 4.71E-48 T 31-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AF_0161 0f6e66e646f199125b4e6e9742c1af79 400 Gene3D G3DSA:3.90.105.10 30 176 3.6E-92 T 31-10-2018 AF_0161 0f6e66e646f199125b4e6e9742c1af79 400 Pfam PF00994 Probable molybdopterin binding domain 182 302 3.1E-27 T 31-10-2018 IPR001453 MoaB/Mog domain AF_0161 0f6e66e646f199125b4e6e9742c1af79 400 SUPERFAMILY SSF53218 179 303 9.55E-36 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily AF_1655 52f61cc446b566c1debb7fe5db5e010f 290 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 86 97 1.7E-5 T 31-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 AF_1655 52f61cc446b566c1debb7fe5db5e010f 290 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 32 47 1.7E-5 T 31-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 AF_1655 52f61cc446b566c1debb7fe5db5e010f 290 Pfam PF00717 Peptidase S24-like 32 100 1.6E-11 T 31-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AF_1655 52f61cc446b566c1debb7fe5db5e010f 290 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 7 143 3.7E-23 T 31-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 AF_1655 52f61cc446b566c1debb7fe5db5e010f 290 SUPERFAMILY SSF51306 29 100 8.11E-11 T 31-10-2018 IPR036286 LexA/Signal peptidase-like superfamily AF_1304 93de374c42f51cc163bc72cc283684e7 223 ProSitePatterns PS00171 Triosephosphate isomerase active site. 140 150 - T 31-10-2018 IPR020861 Triosephosphate isomerase, active site GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1304 93de374c42f51cc163bc72cc283684e7 223 TIGRFAM TIGR00419 tim: triose-phosphate isomerase 6 210 2.0E-86 T 31-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1304 93de374c42f51cc163bc72cc283684e7 223 SUPERFAMILY SSF51351 6 220 3.8E-45 T 31-10-2018 IPR035990 Triosephosphate isomerase superfamily GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1304 93de374c42f51cc163bc72cc283684e7 223 Gene3D G3DSA:3.20.20.70 3 223 3.0E-78 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1304 93de374c42f51cc163bc72cc283684e7 223 Hamap MF_00147_A Triosephosphate isomerase [tpiA]. 4 223 40.607 T 31-10-2018 IPR022891 Triosephosphate isomerase, archaeal GO:0004807|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003 AF_1304 93de374c42f51cc163bc72cc283684e7 223 Pfam PF00121 Triosephosphate isomerase 6 123 1.8E-11 T 31-10-2018 IPR000652 Triosephosphate isomerase GO:0004807 KEGG: 00010+5.3.1.1|KEGG: 00051+5.3.1.1|KEGG: 00562+5.3.1.1|KEGG: 00710+5.3.1.1|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_2157 dec86c7b4774019232d921f37909a0cd 176 SUPERFAMILY SSF55144 1 175 1.29E-46 T 31-10-2018 IPR009097 Cyclic phosphodiesterase AF_2157 dec86c7b4774019232d921f37909a0cd 176 TIGRFAM TIGR02258 2_5_ligase: 2'-5' RNA ligase 1 175 5.3E-59 T 31-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 AF_2157 dec86c7b4774019232d921f37909a0cd 176 Gene3D G3DSA:3.90.1140.10 1 176 6.8E-56 T 31-10-2018 AF_2157 dec86c7b4774019232d921f37909a0cd 176 Pfam PF02834 LigT like Phosphoesterase 92 169 1.2E-12 T 31-10-2018 IPR014051 Phosphoesterase, HXTX AF_2157 dec86c7b4774019232d921f37909a0cd 176 Pfam PF02834 LigT like Phosphoesterase 7 88 3.3E-19 T 31-10-2018 IPR014051 Phosphoesterase, HXTX AF_2157 dec86c7b4774019232d921f37909a0cd 176 Hamap MF_01940 RNA 2',3'-cyclic phosphodiesterase [thpR]. 1 176 24.846 T 31-10-2018 IPR004175 RNA 2',3'-cyclic phosphodiesterase GO:0004113|GO:0008664 AF_0254 bebbf9cc83aeab95e4d2509be092d1cb 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 377 392 2.9E-22 T 31-10-2018 AF_0254 bebbf9cc83aeab95e4d2509be092d1cb 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 2.9E-22 T 31-10-2018 AF_0254 bebbf9cc83aeab95e4d2509be092d1cb 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 2.9E-22 T 31-10-2018 AF_0254 bebbf9cc83aeab95e4d2509be092d1cb 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 276 2.9E-22 T 31-10-2018 AF_0254 bebbf9cc83aeab95e4d2509be092d1cb 439 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 229 243 2.9E-22 T 31-10-2018 AF_0254 bebbf9cc83aeab95e4d2509be092d1cb 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 228 244 1.3E-26 T 31-10-2018 AF_0254 bebbf9cc83aeab95e4d2509be092d1cb 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 276 1.3E-26 T 31-10-2018 AF_0254 bebbf9cc83aeab95e4d2509be092d1cb 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 1.3E-26 T 31-10-2018 AF_0254 bebbf9cc83aeab95e4d2509be092d1cb 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.3E-26 T 31-10-2018 AF_0254 bebbf9cc83aeab95e4d2509be092d1cb 439 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 101 119 1.3E-26 T 31-10-2018 AF_0254 bebbf9cc83aeab95e4d2509be092d1cb 439 Gene3D G3DSA:3.50.50.60 2 332 3.1E-130 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0254 bebbf9cc83aeab95e4d2509be092d1cb 439 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 299 9.3E-58 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AF_0254 bebbf9cc83aeab95e4d2509be092d1cb 439 SUPERFAMILY SSF55424 321 435 6.87E-22 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AF_0254 bebbf9cc83aeab95e4d2509be092d1cb 439 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 324 421 7.5E-15 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AF_0254 bebbf9cc83aeab95e4d2509be092d1cb 439 SUPERFAMILY SSF51905 2 308 4.86E-44 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0254 bebbf9cc83aeab95e4d2509be092d1cb 439 Gene3D G3DSA:3.50.50.60 110 429 3.1E-130 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_2251 e7417dd501df768b806c0d4f57b81333 229 Hamap MF_00226_A Putative competence-damage inducible protein [cinA]. 1 229 39.167 T 31-10-2018 IPR023055 Putative competence-damage inducible protein, Archaea AF_2251 e7417dd501df768b806c0d4f57b81333 229 Pfam PF00994 Probable molybdopterin binding domain 5 157 4.8E-36 T 31-10-2018 IPR001453 MoaB/Mog domain AF_2251 e7417dd501df768b806c0d4f57b81333 229 Gene3D G3DSA:3.40.980.10 2 159 2.4E-48 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily AF_2251 e7417dd501df768b806c0d4f57b81333 229 SUPERFAMILY SSF53218 3 189 1.7E-37 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily AF_2251 e7417dd501df768b806c0d4f57b81333 229 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 1 155 5.3E-39 T 31-10-2018 IPR001453 MoaB/Mog domain AF_2251 e7417dd501df768b806c0d4f57b81333 229 SMART SM00852 4 161 1.5E-34 T 31-10-2018 IPR001453 MoaB/Mog domain AF_0746 3aedbe9fda62e0fca0ca41eb88f6cae1 249 TIGRFAM TIGR00736 nifR3_rel_arch: putative TIM-barrel protein 12 229 1.4E-102 T 31-10-2018 IPR005270 tRNA-dihydrouridine synthase, TIM-barrel, NifR3-related AF_0746 3aedbe9fda62e0fca0ca41eb88f6cae1 249 SUPERFAMILY SSF51395 5 232 2.04E-21 T 31-10-2018 AF_0746 3aedbe9fda62e0fca0ca41eb88f6cae1 249 Gene3D G3DSA:3.20.20.70 3 233 7.1E-15 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0358 324ede3c9f34e7c70b041c9ecef881c1 452 Gene3D G3DSA:3.40.50.300 61 237 1.8E-51 T 31-10-2018 AF_0358 324ede3c9f34e7c70b041c9ecef881c1 452 Gene3D G3DSA:3.40.1170.30 4 60 3.7E-32 T 31-10-2018 AF_0358 324ede3c9f34e7c70b041c9ecef881c1 452 Gene3D G3DSA:3.40.50.300 238 436 9.4E-53 T 31-10-2018 AF_0358 324ede3c9f34e7c70b041c9ecef881c1 452 SUPERFAMILY SSF52540 90 421 3.33E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0358 324ede3c9f34e7c70b041c9ecef881c1 452 Pfam PF16203 ERCC3/RAD25/XPB C-terminal helicase 314 445 1.9E-21 T 31-10-2018 IPR032438 ERCC3/RAD25/XPB helicase, C-terminal domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167246|Reactome: R-HSA-427413|Reactome: R-HSA-5696395|Reactome: R-HSA-5696400|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-72086|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73863|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-77075 AF_0358 324ede3c9f34e7c70b041c9ecef881c1 452 SMART SM00490 340 419 1.9E-15 T 31-10-2018 IPR001650 Helicase, C-terminal AF_0358 324ede3c9f34e7c70b041c9ecef881c1 452 SMART SM00487 70 233 5.7E-25 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AF_0358 324ede3c9f34e7c70b041c9ecef881c1 452 Pfam PF04851 Type III restriction enzyme, res subunit 72 210 1.0E-27 T 31-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AF_0317 560ed8aac9baf8a776ed95e15a8e5677 149 SUPERFAMILY SSF88723 2 143 1.49E-17 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_0317 560ed8aac9baf8a776ed95e15a8e5677 149 Pfam PF01850 PIN domain 2 144 2.2E-32 T 31-10-2018 IPR002716 PIN domain AF_0317 560ed8aac9baf8a776ed95e15a8e5677 149 Gene3D G3DSA:3.40.50.1010 2 147 1.4E-14 T 31-10-2018 AF_0317 560ed8aac9baf8a776ed95e15a8e5677 149 SMART SM00670 1 140 1.6E-9 T 31-10-2018 IPR002716 PIN domain AF_1875 48f00f3c9a5d03c02e8ba5fccecb0ab9 241 Gene3D G3DSA:1.10.3210.30 1 210 4.3E-22 T 31-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily AF_1875 48f00f3c9a5d03c02e8ba5fccecb0ab9 241 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 16 217 2.3E-14 T 31-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain AF_0469 32f8d044482378de32aa4c69c0c8c75c 346 Gene3D G3DSA:3.40.50.970 1 191 9.1E-76 T 31-10-2018 AF_0469 32f8d044482378de32aa4c69c0c8c75c 346 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 249 329 2.4E-16 T 31-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II AF_0469 32f8d044482378de32aa4c69c0c8c75c 346 SUPERFAMILY SSF52518 3 234 1.02E-69 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold AF_0469 32f8d044482378de32aa4c69c0c8c75c 346 SUPERFAMILY SSF52922 247 342 7.98E-18 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AF_0469 32f8d044482378de32aa4c69c0c8c75c 346 Gene3D G3DSA:3.40.50.920 240 344 7.6E-17 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AF_0469 32f8d044482378de32aa4c69c0c8c75c 346 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 15 195 7.8E-70 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 AF_1915 d579c46c8e902499a0d9b22824cb4c16 132 SUPERFAMILY SSF50193 2 132 3.66E-46 T 31-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 AF_1915 d579c46c8e902499a0d9b22824cb4c16 132 ProSitePatterns PS00049 Ribosomal protein L14 signature. 71 97 - T 31-10-2018 IPR019972 Ribosomal protein L14P, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1915 d579c46c8e902499a0d9b22824cb4c16 132 Pfam PF00238 Ribosomal protein L14p/L23e 14 131 4.0E-37 T 31-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AF_1915 d579c46c8e902499a0d9b22824cb4c16 132 Hamap MF_01367 50S ribosomal protein L14 [rplN]. 11 132 20.628 T 31-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AF_1915 d579c46c8e902499a0d9b22824cb4c16 132 Gene3D G3DSA:2.40.150.20 1 132 3.6E-52 T 31-10-2018 IPR036853 Ribosomal protein L14 superfamily GO:0003735|GO:0005840|GO:0006412 AF_1915 d579c46c8e902499a0d9b22824cb4c16 132 TIGRFAM TIGR03673 uL14_arch: 50S ribosomal protein uL14 2 132 3.5E-65 T 31-10-2018 IPR019971 Ribosomal protein L14P, archaeal AF_1915 d579c46c8e902499a0d9b22824cb4c16 132 SMART SM01374 11 132 3.4E-61 T 31-10-2018 IPR000218 Ribosomal protein L14P GO:0003735|GO:0005840|GO:0006412 AF_0690 ade563eb21fe849746727fc35a0f1935 252 SUPERFAMILY SSF52768 4 199 3.6E-20 T 31-10-2018 IPR023696 Ureohydrolase domain superfamily AF_0690 ade563eb21fe849746727fc35a0f1935 252 Gene3D G3DSA:3.40.800.20 12 237 2.4E-15 T 31-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_0690 ade563eb21fe849746727fc35a0f1935 252 Pfam PF00850 Histone deacetylase domain 68 134 1.1E-9 T 31-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_0690 ade563eb21fe849746727fc35a0f1935 252 PRINTS PR01270 Histone deacetylase superfamily signature 122 137 5.9E-8 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_0690 ade563eb21fe849746727fc35a0f1935 252 PRINTS PR01270 Histone deacetylase superfamily signature 91 114 5.9E-8 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_0690 ade563eb21fe849746727fc35a0f1935 252 PRINTS PR01270 Histone deacetylase superfamily signature 187 197 5.9E-8 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_2410 2e6a72df6c5efb613b09d1f43dee5da9 153 Pfam PF10061 Uncharacterized conserved protein (DUF2299) 2 137 1.5E-49 T 31-10-2018 IPR018747 Protein of unknown function DUF2299 AF_2410 2e6a72df6c5efb613b09d1f43dee5da9 153 Gene3D G3DSA:3.30.1460.10 1 142 5.8E-53 T 31-10-2018 AF_0487 da5b1e8c15191e21d7617eeda6ce1ba6 777 Gene3D G3DSA:2.30.120.10 314 379 6.6E-135 T 31-10-2018 AF_0487 da5b1e8c15191e21d7617eeda6ce1ba6 777 PIRSF PIRSF001227 8 769 2.2E-171 T 31-10-2018 IPR014395 Penicillin/GL-7-ACA/AHL acylase GO:0016811 AF_0487 da5b1e8c15191e21d7617eeda6ce1ba6 777 Gene3D G3DSA:3.60.20.10 242 756 6.6E-135 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AF_0487 da5b1e8c15191e21d7617eeda6ce1ba6 777 Gene3D G3DSA:1.10.439.10 29 182 2.1E-46 T 31-10-2018 IPR023343 Penicillin amidase type, domain 1 GO:0016811 AF_0487 da5b1e8c15191e21d7617eeda6ce1ba6 777 Gene3D G3DSA:1.10.1400.10 546 671 6.6E-135 T 31-10-2018 AF_0487 da5b1e8c15191e21d7617eeda6ce1ba6 777 SUPERFAMILY SSF56235 50 764 1.39E-191 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AF_0487 da5b1e8c15191e21d7617eeda6ce1ba6 777 Pfam PF01804 Penicillin amidase 50 764 3.8E-201 T 31-10-2018 IPR002692 Penicillin/GL-7-ACA/AHL/aculeacin-A acylase GO:0016787|GO:0017000 AF_1145 fb8cd0b83500ef43b51c87fbed9d4a0d 482 SUPERFAMILY SSF100950 204 472 1.05E-57 T 31-10-2018 IPR037171 NagB/RpiA transferase-like AF_1145 fb8cd0b83500ef43b51c87fbed9d4a0d 482 Gene3D G3DSA:3.40.1080.20 315 466 1.2E-52 T 31-10-2018 IPR038460 Acetyl-CoA hydrolase/transferase, C-terminal domain superfamily AF_1145 fb8cd0b83500ef43b51c87fbed9d4a0d 482 Pfam PF13336 Acetyl-CoA hydrolase/transferase C-terminal domain 297 457 1.1E-55 T 31-10-2018 IPR026888 Acetyl-CoA hydrolase/transferase C-terminal domain AF_1145 fb8cd0b83500ef43b51c87fbed9d4a0d 482 Gene3D G3DSA:3.30.750.70 205 314 1.7E-32 T 31-10-2018 AF_1145 fb8cd0b83500ef43b51c87fbed9d4a0d 482 SUPERFAMILY SSF100950 9 246 1.22E-26 T 31-10-2018 IPR037171 NagB/RpiA transferase-like AF_1145 fb8cd0b83500ef43b51c87fbed9d4a0d 482 Gene3D G3DSA:3.40.1080.10 5 196 1.6E-46 T 31-10-2018 AF_1145 fb8cd0b83500ef43b51c87fbed9d4a0d 482 Pfam PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain 9 201 6.7E-84 T 31-10-2018 IPR003702 Acetyl-CoA hydrolase/transferase GO:0003824|GO:0006084 AF_0948 6d6d9e53698467ebc1121fe6eb9de0e9 147 Gene3D G3DSA:3.30.460.10 5 120 5.5E-11 T 31-10-2018 AF_0948 6d6d9e53698467ebc1121fe6eb9de0e9 147 Pfam PF01909 Nucleotidyltransferase domain 14 96 3.8E-8 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AF_0948 6d6d9e53698467ebc1121fe6eb9de0e9 147 SUPERFAMILY SSF81301 11 107 2.18E-17 T 31-10-2018 AF_1750 1b3fb3999d94fabd083ee870fcaa0c7d 120 Pfam PF00543 Nitrogen regulatory protein P-II 15 116 6.5E-38 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AF_1750 1b3fb3999d94fabd083ee870fcaa0c7d 120 SUPERFAMILY SSF54913 12 118 3.81E-39 T 31-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta AF_1750 1b3fb3999d94fabd083ee870fcaa0c7d 120 PRINTS PR00340 P-II protein signature 34 52 3.8E-39 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AF_1750 1b3fb3999d94fabd083ee870fcaa0c7d 120 PRINTS PR00340 P-II protein signature 13 28 3.8E-39 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AF_1750 1b3fb3999d94fabd083ee870fcaa0c7d 120 PRINTS PR00340 P-II protein signature 63 86 3.8E-39 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AF_1750 1b3fb3999d94fabd083ee870fcaa0c7d 120 PRINTS PR00340 P-II protein signature 94 114 3.8E-39 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AF_1750 1b3fb3999d94fabd083ee870fcaa0c7d 120 Gene3D G3DSA:3.30.70.120 12 120 5.7E-45 T 31-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AF_1750 1b3fb3999d94fabd083ee870fcaa0c7d 120 SMART SM00938 15 116 7.4E-56 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AF_1750 1b3fb3999d94fabd083ee870fcaa0c7d 120 ProSitePatterns PS00638 P-II protein C-terminal region signature. 94 107 - T 31-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 AF_2006 2effad4654e5020e1218d9dfeab2ecdb 296 Gene3D G3DSA:3.20.20.70 1 295 1.6E-73 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_2006 2effad4654e5020e1218d9dfeab2ecdb 296 TIGRFAM TIGR02668 moaA_archaeal: probable molybdenum cofactor biosynthesis protein A 2 295 8.6E-122 T 31-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 AF_2006 2effad4654e5020e1218d9dfeab2ecdb 296 Pfam PF04055 Radical SAM superfamily 17 170 3.1E-33 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_2006 2effad4654e5020e1218d9dfeab2ecdb 296 SMART SM00729 11 212 1.2E-14 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AF_2006 2effad4654e5020e1218d9dfeab2ecdb 296 Pfam PF06463 Molybdenum Cofactor Synthesis C 201 294 4.9E-18 T 31-10-2018 IPR010505 Molybdenum cofactor synthesis C-terminal GO:0006777|GO:0019008|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AF_2006 2effad4654e5020e1218d9dfeab2ecdb 296 Hamap MF_01225_A GTP 3',8-cyclase [moaA]. 2 295 43.854 T 31-10-2018 IPR013485 Molybdenum cofactor biosynthesis protein A, archaea GO:0006777|GO:0046872 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823 AF_2006 2effad4654e5020e1218d9dfeab2ecdb 296 SUPERFAMILY SSF102114 3 269 2.75E-66 T 31-10-2018 AF_2006 2effad4654e5020e1218d9dfeab2ecdb 296 Pfam PF13353 4Fe-4S single cluster domain 18 113 6.8E-7 T 31-10-2018 AF_2006 2effad4654e5020e1218d9dfeab2ecdb 296 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 17 28 - T 31-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AF_0270 2eef4e815b0333235b759f515642b84d 195 Hamap MF_00401 Peroxiredoxin. 1 195 47.649 T 31-10-2018 IPR022915 Peroxiredoxin, TDXH subfamily GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AF_0270 2eef4e815b0333235b759f515642b84d 195 PIRSF PIRSF000239 1 194 1.5E-70 T 31-10-2018 IPR024706 Peroxiredoxin, AhpC-type KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AF_0270 2eef4e815b0333235b759f515642b84d 195 Pfam PF00578 AhpC/TSA family 6 114 6.9E-29 T 31-10-2018 IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant GO:0016209|GO:0016491|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AF_0270 2eef4e815b0333235b759f515642b84d 195 Pfam PF10417 C-terminal domain of 1-Cys peroxiredoxin 135 177 6.9E-12 T 31-10-2018 IPR019479 Peroxiredoxin, C-terminal GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15|Reactome: R-HSA-3299685 AF_0270 2eef4e815b0333235b759f515642b84d 195 Gene3D G3DSA:3.40.30.10 1 124 4.2E-40 T 31-10-2018 AF_0270 2eef4e815b0333235b759f515642b84d 195 Gene3D G3DSA:3.30.1020.10 125 195 6.9E-33 T 31-10-2018 AF_0270 2eef4e815b0333235b759f515642b84d 195 SUPERFAMILY SSF52833 3 195 5.47E-64 T 31-10-2018 IPR036249 Thioredoxin-like superfamily AF_0382 58ad6488e9449d65ba831929da7b0acf 236 SUPERFAMILY SSF50249 151 230 1.22E-7 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0382 58ad6488e9449d65ba831929da7b0acf 236 Gene3D G3DSA:2.40.50.140 150 236 1.1E-6 T 31-10-2018 AF_0382 58ad6488e9449d65ba831929da7b0acf 236 SUPERFAMILY SSF50249 45 148 6.28E-11 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0382 58ad6488e9449d65ba831929da7b0acf 236 Gene3D G3DSA:2.40.50.140 54 148 2.4E-13 T 31-10-2018 AF_2282 00815dc52ad390fbd6e93a60886d4fde 264 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 173 184 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_2282 00815dc52ad390fbd6e93a60886d4fde 264 Pfam PF13187 4Fe-4S dicluster domain 172 218 2.1E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_2282 00815dc52ad390fbd6e93a60886d4fde 264 ProSitePatterns PS00446 RNA polymerases D / 30 to 40 Kd subunits signature. 28 68 - T 31-10-2018 IPR001514 DNA-directed RNA polymerase, 30-40kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 AF_2282 00815dc52ad390fbd6e93a60886d4fde 264 Pfam PF01193 RNA polymerase Rpb3/Rpb11 dimerisation domain 16 252 1.0E-14 T 31-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_2282 00815dc52ad390fbd6e93a60886d4fde 264 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 203 214 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_2282 00815dc52ad390fbd6e93a60886d4fde 264 SUPERFAMILY SSF56553 39 155 7.85E-30 T 31-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_2282 00815dc52ad390fbd6e93a60886d4fde 264 Pfam PF01000 RNA polymerase Rpb3/RpoA insert domain 46 154 3.0E-27 T 31-10-2018 IPR011262 DNA-directed RNA polymerase, insert domain GO:0003899|GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_2282 00815dc52ad390fbd6e93a60886d4fde 264 SMART SM00662 14 259 3.4E-102 T 31-10-2018 IPR011263 DNA-directed RNA polymerase, RpoA/D/Rpb3-type GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_2282 00815dc52ad390fbd6e93a60886d4fde 264 Gene3D G3DSA:3.30.70.3110 164 223 8.5E-86 T 31-10-2018 AF_2282 00815dc52ad390fbd6e93a60886d4fde 264 Hamap MF_00320 DNA-directed RNA polymerase subunit D [rpoD]. 3 262 36.804 T 31-10-2018 IPR022842 DNA-directed RNA polymerase subunit D (Rpo3) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_2282 00815dc52ad390fbd6e93a60886d4fde 264 Gene3D G3DSA:2.170.120.12 40 153 8.5E-86 T 31-10-2018 IPR036643 DNA-directed RNA polymerase, insert domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_2282 00815dc52ad390fbd6e93a60886d4fde 264 Gene3D G3DSA:3.30.1360.10 6 256 8.5E-86 T 31-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_2282 00815dc52ad390fbd6e93a60886d4fde 264 SUPERFAMILY SSF55257 3 262 5.81E-29 T 31-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_0538 81ac2b59947e24971386361ad25f1cd4 157 SUPERFAMILY SSF46906 64 136 6.28E-23 T 31-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily AF_0538 81ac2b59947e24971386361ad25f1cd4 157 Gene3D G3DSA:2.10.260.30 1 67 5.9E-30 T 31-10-2018 AF_0538 81ac2b59947e24971386361ad25f1cd4 157 SUPERFAMILY SSF54747 2 80 2.88E-27 T 31-10-2018 IPR036796 Ribosomal protein L11/L12, N-terminal domain superfamily AF_0538 81ac2b59947e24971386361ad25f1cd4 157 ProDom PD001367 RIBOSOMAL RIBONUCLEOPROTEIN L11 RRNA-BINDING RNA-BINDING METHYLATION 50S L11 BACTERIAL CHLOROPLAST 38 69 0.004 T 31-10-2018 AF_0538 81ac2b59947e24971386361ad25f1cd4 157 ProSitePatterns PS00359 Ribosomal protein L11 signature. 122 137 - T 31-10-2018 IPR020785 Ribosomal protein L11, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0538 81ac2b59947e24971386361ad25f1cd4 157 Gene3D G3DSA:1.10.10.250 71 156 1.2E-31 T 31-10-2018 IPR036769 Ribosomal protein L11, C-terminal domain superfamily AF_0538 81ac2b59947e24971386361ad25f1cd4 157 Pfam PF03946 Ribosomal protein L11, N-terminal domain 5 62 8.6E-26 T 31-10-2018 IPR020784 Ribosomal protein L11, N-terminal AF_0538 81ac2b59947e24971386361ad25f1cd4 157 Pfam PF00298 Ribosomal protein L11, RNA binding domain 69 135 2.6E-24 T 31-10-2018 IPR020783 Ribosomal protein L11, C-terminal GO:0003735|GO:0005840|GO:0006412 AF_0538 81ac2b59947e24971386361ad25f1cd4 157 SMART SM00649 5 136 4.0E-73 T 31-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 AF_0538 81ac2b59947e24971386361ad25f1cd4 157 Hamap MF_00736 50S ribosomal protein L11 [rplK]. 1 137 29.828 T 31-10-2018 IPR000911 Ribosomal protein L11/L12 GO:0003735|GO:0005840|GO:0006412 AF_1223 b669485060dbffb0c8478086f17fcde7 275 SUPERFAMILY SSF103481 35 128 8.11E-11 T 31-10-2018 AF_1223 b669485060dbffb0c8478086f17fcde7 275 SUPERFAMILY SSF103481 172 270 2.48E-7 T 31-10-2018 AF_1223 b669485060dbffb0c8478086f17fcde7 275 Pfam PF00892 EamA-like transporter family 134 267 3.3E-9 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AF_1223 b669485060dbffb0c8478086f17fcde7 275 Pfam PF00892 EamA-like transporter family 4 125 2.6E-8 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AF_2289 344e23b61ead935b3aafb7806328efd8 284 Hamap MF_00217 Mevalonate kinase [mvk]. 1 280 52.586 T 31-10-2018 IPR022937 Mevalonate kinase, archaeal GO:0004496 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922 AF_2289 344e23b61ead935b3aafb7806328efd8 284 SUPERFAMILY SSF55060 161 267 2.67E-24 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily AF_2289 344e23b61ead935b3aafb7806328efd8 284 PRINTS PR00959 Mevalonate kinase family signature 5 29 8.8E-28 T 31-10-2018 AF_2289 344e23b61ead935b3aafb7806328efd8 284 PRINTS PR00959 Mevalonate kinase family signature 83 105 8.8E-28 T 31-10-2018 AF_2289 344e23b61ead935b3aafb7806328efd8 284 PRINTS PR00959 Mevalonate kinase family signature 126 145 8.8E-28 T 31-10-2018 AF_2289 344e23b61ead935b3aafb7806328efd8 284 PRINTS PR00959 Mevalonate kinase family signature 246 263 8.8E-28 T 31-10-2018 AF_2289 344e23b61ead935b3aafb7806328efd8 284 TIGRFAM TIGR00549 mevalon_kin: mevalonate kinase 5 260 4.0E-81 T 31-10-2018 IPR006205 Mevalonate kinase GO:0004496|GO:0005524|GO:0005737|GO:0008299 KEGG: 00900+2.7.1.36|MetaCyc: PWY-6174|MetaCyc: PWY-7391|MetaCyc: PWY-922|Reactome: R-HSA-191273|Reactome: R-HSA-2426168 AF_2289 344e23b61ead935b3aafb7806328efd8 284 Gene3D G3DSA:3.30.70.890 160 281 9.8E-30 T 31-10-2018 IPR036554 GHMP kinase, C-terminal domain superfamily AF_2289 344e23b61ead935b3aafb7806328efd8 284 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 85 96 - T 31-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 AF_2289 344e23b61ead935b3aafb7806328efd8 284 Pfam PF08544 GHMP kinases C terminal 203 264 1.6E-13 T 31-10-2018 IPR013750 GHMP kinase, C-terminal domain AF_2289 344e23b61ead935b3aafb7806328efd8 284 SUPERFAMILY SSF54211 1 168 3.57E-41 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AF_2289 344e23b61ead935b3aafb7806328efd8 284 Pfam PF00288 GHMP kinases N terminal domain 79 145 1.1E-18 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 AF_2289 344e23b61ead935b3aafb7806328efd8 284 Gene3D G3DSA:3.30.230.10 1 159 6.0E-53 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AF_2426 08d22c7458badbca148fd6739d421804 282 Gene3D G3DSA:3.30.200.20 91 184 1.6E-30 T 31-10-2018 AF_2426 08d22c7458badbca148fd6739d421804 282 Pfam PF01163 RIO1 family 106 272 7.4E-46 T 31-10-2018 AF_2426 08d22c7458badbca148fd6739d421804 282 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 214 226 - T 31-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 AF_2426 08d22c7458badbca148fd6739d421804 282 Gene3D G3DSA:1.10.10.10 1 90 5.4E-43 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_2426 08d22c7458badbca148fd6739d421804 282 Pfam PF09202 Rio2, N-terminal 10 86 1.4E-8 T 31-10-2018 IPR015285 RIO2 kinase winged helix domain, N-terminal GO:0004674|GO:0005524|GO:0006468 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 AF_2426 08d22c7458badbca148fd6739d421804 282 Gene3D G3DSA:1.10.510.10 185 282 5.1E-29 T 31-10-2018 AF_2426 08d22c7458badbca148fd6739d421804 282 SUPERFAMILY SSF46785 2 89 5.58E-22 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_2426 08d22c7458badbca148fd6739d421804 282 SMART SM00090 49 281 8.0E-94 T 31-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 AF_2426 08d22c7458badbca148fd6739d421804 282 SUPERFAMILY SSF56112 94 277 4.32E-34 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily AF_2400 538352b9c33d1c23ce49226bb39f3276 836 Gene3D G3DSA:3.10.620.30 177 338 2.6E-20 T 31-10-2018 AF_2400 538352b9c33d1c23ce49226bb39f3276 836 SUPERFAMILY SSF54001 200 412 1.14E-23 T 31-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AF_2400 538352b9c33d1c23ce49226bb39f3276 836 SMART SM00460 248 315 9.5E-21 T 31-10-2018 IPR002931 Transglutaminase-like AF_2400 538352b9c33d1c23ce49226bb39f3276 836 Pfam PF01841 Transglutaminase-like superfamily 206 313 8.2E-25 T 31-10-2018 IPR002931 Transglutaminase-like AF_1663 672860b8b1f1d5b48be7b625ce71fb5e 96 Pfam PF14947 Winged helix-turn-helix 5 82 1.9E-23 T 31-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain AF_1663 672860b8b1f1d5b48be7b625ce71fb5e 96 Gene3D G3DSA:1.10.10.10 1 95 1.3E-27 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1663 672860b8b1f1d5b48be7b625ce71fb5e 96 SUPERFAMILY SSF46785 6 92 1.76E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_2385 f0832e8e86c0a6ca0b7a81ff02a94ad0 182 SUPERFAMILY SSF54862 1 180 6.07E-73 T 31-10-2018 AF_2385 f0832e8e86c0a6ca0b7a81ff02a94ad0 182 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 91 102 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_2385 f0832e8e86c0a6ca0b7a81ff02a94ad0 182 Pfam PF13247 4Fe-4S dicluster domain 51 146 3.0E-24 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_2385 f0832e8e86c0a6ca0b7a81ff02a94ad0 182 Gene3D G3DSA:3.30.70.20 32 182 5.2E-66 T 31-10-2018 AF_2385 f0832e8e86c0a6ca0b7a81ff02a94ad0 182 Gene3D G3DSA:3.30.70.20 1 31 2.5E-6 T 31-10-2018 AF_0581 04af1677bf893a2a74f77270a21ae577 581 Pfam PF00535 Glycosyl transferase family 2 57 221 1.2E-33 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AF_0581 04af1677bf893a2a74f77270a21ae577 581 Gene3D G3DSA:3.90.550.10 38 297 5.8E-53 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0581 04af1677bf893a2a74f77270a21ae577 581 SUPERFAMILY SSF53448 52 300 5.94E-48 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0581 04af1677bf893a2a74f77270a21ae577 581 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 294 437 5.7E-12 T 31-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AF_0581 04af1677bf893a2a74f77270a21ae577 581 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 459 574 1.5E-13 T 31-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AF_0581 04af1677bf893a2a74f77270a21ae577 581 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 294 564 4.6E-42 T 31-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AF_1101 459f4bec347e4cf99eddbc1cef44cfef 184 SUPERFAMILY SSF52467 28 184 8.51E-49 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AF_1101 459f4bec347e4cf99eddbc1cef44cfef 184 Pfam PF02552 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit 8 181 5.5E-68 T 31-10-2018 IPR003704 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GO:0019385 AF_1101 459f4bec347e4cf99eddbc1cef44cfef 184 PIRSF PIRSF006035 8 184 3.8E-77 T 31-10-2018 IPR003704 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GO:0019385 AF_1101 459f4bec347e4cf99eddbc1cef44cfef 184 Gene3D G3DSA:3.40.50.1220 23 184 2.0E-56 T 31-10-2018 AF_1101 459f4bec347e4cf99eddbc1cef44cfef 184 TIGRFAM TIGR00315 cdhB: CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit 18 183 1.2E-76 T 31-10-2018 IPR003704 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GO:0019385 AF_1101 459f4bec347e4cf99eddbc1cef44cfef 184 Hamap MF_01134 Acetyl-CoA decarbonylase/synthase complex subunit epsilon [cdhB]. 11 183 38.221 T 31-10-2018 IPR003704 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GO:0019385 AF_0682 85a0807a1624f54d1635a5206eee9b69 236 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 142 153 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0682 85a0807a1624f54d1635a5206eee9b69 236 Pfam PF13183 4Fe-4S dicluster domain 141 212 1.4E-10 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0682 85a0807a1624f54d1635a5206eee9b69 236 ProSitePatterns PS00197 2Fe-2S ferredoxin-type iron-sulfur binding region signature. 50 58 - T 31-10-2018 IPR006058 2Fe-2S ferredoxin, iron-sulphur binding site GO:0051537 AF_0682 85a0807a1624f54d1635a5206eee9b69 236 SUPERFAMILY SSF54292 2 96 1.97E-28 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AF_0682 85a0807a1624f54d1635a5206eee9b69 236 Pfam PF13085 2Fe-2S iron-sulfur cluster binding domain 4 103 9.2E-34 T 31-10-2018 IPR025192 Succinate dehydogenase/fumarate reductase N-terminal GO:0009055|GO:0051536 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_0682 85a0807a1624f54d1635a5206eee9b69 236 SUPERFAMILY SSF46548 101 225 3.49E-31 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_0682 85a0807a1624f54d1635a5206eee9b69 236 TIGRFAM TIGR00384 dhsB: succinate dehydrogenase and fumarate reductase iron-sulfur protein 6 222 8.9E-92 T 31-10-2018 IPR004489 Succinate dehydrogenase/fumarate reductase iron-sulphur protein GO:0006099|GO:0016491|GO:0055114 KEGG: 00020+1.3.5.1|KEGG: 00190+1.3.5.1|KEGG: 00650+1.3.5.1|KEGG: 00720+1.3.5.1|MetaCyc: PWY-3781|MetaCyc: PWY-4302|MetaCyc: PWY-561|MetaCyc: PWY-5690|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7254|MetaCyc: PWY-7279|Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_0682 85a0807a1624f54d1635a5206eee9b69 236 Gene3D G3DSA:1.10.1060.10 99 231 2.4E-43 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_0682 85a0807a1624f54d1635a5206eee9b69 236 Gene3D G3DSA:3.10.20.30 1 98 1.4E-36 T 31-10-2018 IPR012675 Beta-grasp domain superfamily AF_2227 d9d2f897fb5fda310a4e428091543e2c 322 Gene3D G3DSA:1.10.10.10 5 82 1.8E-10 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_2227 d9d2f897fb5fda310a4e428091543e2c 322 Gene3D G3DSA:3.30.70.1360 98 318 5.3E-48 T 31-10-2018 IPR036984 NrpR domain superfamily AF_2227 d9d2f897fb5fda310a4e428091543e2c 322 SUPERFAMILY SSF46785 7 76 1.72E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_2227 d9d2f897fb5fda310a4e428091543e2c 322 Pfam PF08461 Ribonuclease R winged-helix domain 10 74 7.1E-24 T 31-10-2018 IPR013668 Ribonuclease R winged-helix domain AF_2227 d9d2f897fb5fda310a4e428091543e2c 322 Pfam PF01995 Domain of unknown function DUF128 84 320 3.0E-62 T 31-10-2018 IPR002846 NrpR regulatory domain AF_2227 d9d2f897fb5fda310a4e428091543e2c 322 Gene3D G3DSA:3.30.70.1360 166 291 5.3E-48 T 31-10-2018 IPR036984 NrpR domain superfamily AF_1021 d4b15235d771d8a8645f2fe7a397286e 275 Gene3D G3DSA:3.40.50.300 1 232 1.2E-64 T 31-10-2018 AF_1021 d4b15235d771d8a8645f2fe7a397286e 275 Pfam PF00005 ABC transporter 18 149 1.3E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_1021 d4b15235d771d8a8645f2fe7a397286e 275 SMART SM00382 26 206 2.5E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1021 d4b15235d771d8a8645f2fe7a397286e 275 ProSitePatterns PS00211 ABC transporters family signature. 122 136 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_1021 d4b15235d771d8a8645f2fe7a397286e 275 SUPERFAMILY SSF52540 1 221 2.83E-62 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0882 798092cd85843bfc70e921cd36e73bf9 418 TIGRFAM TIGR00519 asnASE_I: L-asparaginase, type I 80 414 1.0E-165 T 31-10-2018 IPR006033 L-asparaginase, type I GO:0004067|GO:0006520 Reactome: R-HSA-70614 AF_0882 798092cd85843bfc70e921cd36e73bf9 418 Pfam PF00710 Asparaginase, N-terminal 83 272 2.0E-62 T 31-10-2018 IPR027474 L-asparaginase, N-terminal Reactome: R-HSA-70614 AF_0882 798092cd85843bfc70e921cd36e73bf9 418 Gene3D G3DSA:3.40.50.1170 74 286 8.7E-76 T 31-10-2018 IPR037152 L-asparaginase, N-terminal domain superfamily Reactome: R-HSA-70614 AF_0882 798092cd85843bfc70e921cd36e73bf9 418 SUPERFAMILY SSF141300 2 64 5.36E-15 T 31-10-2018 IPR037222 GatD, N-terminal AF_0882 798092cd85843bfc70e921cd36e73bf9 418 Gene3D G3DSA:2.30.30.520 9 73 4.3E-8 T 31-10-2018 IPR037222 GatD, N-terminal AF_0882 798092cd85843bfc70e921cd36e73bf9 418 SMART SM00870 82 401 1.2E-146 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AF_0882 798092cd85843bfc70e921cd36e73bf9 418 PIRSF PIRSF001220 77 412 3.4E-102 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AF_0882 798092cd85843bfc70e921cd36e73bf9 418 PIRSF PIRSF500175 14 418 7.0E-180 T 31-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 AF_0882 798092cd85843bfc70e921cd36e73bf9 418 ProSitePatterns PS00917 Asparaginase / glutaminase active site signature 2. 159 169 - T 31-10-2018 IPR027475 Asparaginase/glutaminase, active site 2 Reactome: R-HSA-70614 AF_0882 798092cd85843bfc70e921cd36e73bf9 418 TIGRFAM TIGR02153 gatD_arch: glutamyl-tRNA(Gln) amidotransferase, subunit D 28 417 4.8E-184 T 31-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 AF_0882 798092cd85843bfc70e921cd36e73bf9 418 SUPERFAMILY SSF53774 75 415 1.1E-109 T 31-10-2018 IPR036152 Asparaginase/glutaminase-like superfamily Reactome: R-HSA-70614 AF_0882 798092cd85843bfc70e921cd36e73bf9 418 ProSitePatterns PS00144 Asparaginase / glutaminase active site signature 1. 85 93 - T 31-10-2018 IPR020827 Asparaginase/glutaminase, active site 1 GO:0006520 AF_0882 798092cd85843bfc70e921cd36e73bf9 418 PRINTS PR00139 Asparaginase/glutaminase family signature 83 94 2.2E-14 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AF_0882 798092cd85843bfc70e921cd36e73bf9 418 PRINTS PR00139 Asparaginase/glutaminase family signature 158 176 2.2E-14 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AF_0882 798092cd85843bfc70e921cd36e73bf9 418 PRINTS PR00139 Asparaginase/glutaminase family signature 339 357 2.2E-14 T 31-10-2018 IPR006034 Asparaginase/glutaminase-like Reactome: R-HSA-70614 AF_0882 798092cd85843bfc70e921cd36e73bf9 418 Hamap MF_00586 Glutamyl-tRNA(Gln) amidotransferase subunit D [gatD]. 20 417 47.625 T 31-10-2018 IPR011878 Glutamyl-tRNA(Gln) amidotransferase subunit D GO:0006450 AF_0882 798092cd85843bfc70e921cd36e73bf9 418 Gene3D G3DSA:3.40.50.40 288 418 5.3E-44 T 31-10-2018 IPR027473 L-asparaginase, C-terminal Reactome: R-HSA-70614 AF_2243 f7c2466c93a85380f64d0af5f095665b 414 Pfam PF02803 Thiolase, C-terminal domain 290 410 2.8E-43 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 AF_2243 f7c2466c93a85380f64d0af5f095665b 414 ProSitePatterns PS00737 Thiolases signature 2. 358 374 - T 31-10-2018 IPR020613 Thiolase, conserved site GO:0016747 AF_2243 f7c2466c93a85380f64d0af5f095665b 414 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 6 410 7.3E-118 T 31-10-2018 IPR002155 Thiolase GO:0016747 AF_2243 f7c2466c93a85380f64d0af5f095665b 414 Pfam PF00108 Thiolase, N-terminal domain 4 281 3.2E-54 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AF_2243 f7c2466c93a85380f64d0af5f095665b 414 SUPERFAMILY SSF53901 290 410 1.44E-39 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_2243 f7c2466c93a85380f64d0af5f095665b 414 Gene3D G3DSA:3.40.47.10 1 412 1.1E-119 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_2243 f7c2466c93a85380f64d0af5f095665b 414 PIRSF PIRSF000429 1 413 8.3E-113 T 31-10-2018 IPR002155 Thiolase GO:0016747 AF_2243 f7c2466c93a85380f64d0af5f095665b 414 SUPERFAMILY SSF53901 1 287 3.4E-54 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_2060 9ca5b19c909e221d64578afcd06320ba 319 Pfam PF08542 Replication factor C C-terminal domain 227 311 2.1E-25 T 31-10-2018 IPR013748 Replication factor C, C-terminal Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-176187|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685938|Reactome: R-HSA-5685942|Reactome: R-HSA-5693607|Reactome: R-HSA-5693616|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6804756|Reactome: R-HSA-69091|Reactome: R-HSA-69473 AF_2060 9ca5b19c909e221d64578afcd06320ba 319 Gene3D G3DSA:1.20.272.10 227 319 1.2E-37 T 31-10-2018 AF_2060 9ca5b19c909e221d64578afcd06320ba 319 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 41 158 3.4E-18 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AF_2060 9ca5b19c909e221d64578afcd06320ba 319 Gene3D G3DSA:3.40.50.300 1 160 1.3E-60 T 31-10-2018 AF_2060 9ca5b19c909e221d64578afcd06320ba 319 Gene3D G3DSA:1.10.8.60 161 226 1.2E-29 T 31-10-2018 AF_2060 9ca5b19c909e221d64578afcd06320ba 319 Hamap MF_01509 Replication factor C small subunit [rfcS]. 3 317 52.829 T 31-10-2018 IPR023748 Replication factor C small subunit, archaeal GO:0003689|GO:0005524|GO:0005663|GO:0006260 AF_2060 9ca5b19c909e221d64578afcd06320ba 319 SUPERFAMILY SSF48019 227 316 3.7E-25 T 31-10-2018 IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal GO:0003677|GO:0006260 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-174411|Reactome: R-HSA-5651801|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5685942|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-69091 AF_2060 9ca5b19c909e221d64578afcd06320ba 319 SMART SM00382 37 162 5.5E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_2060 9ca5b19c909e221d64578afcd06320ba 319 SUPERFAMILY SSF52540 6 221 1.2E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2287 de1d43e930a2dbef9992297bc21c956e 317 Gene3D G3DSA:3.20.20.70 1 317 6.1E-116 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_2287 de1d43e930a2dbef9992297bc21c956e 317 SUPERFAMILY SSF51395 1 315 1.31E-79 T 31-10-2018 AF_2287 de1d43e930a2dbef9992297bc21c956e 317 Pfam PF01070 FMN-dependent dehydrogenase 143 299 2.8E-16 T 31-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 AF_2287 de1d43e930a2dbef9992297bc21c956e 317 Hamap MF_00354 Isopentenyl-diphosphate delta-isomerase [fni]. 1 307 36.598 T 31-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 AF_2287 de1d43e930a2dbef9992297bc21c956e 317 TIGRFAM TIGR02151 IPP_isom_2: isopentenyl-diphosphate delta-isomerase, type 2 2 306 9.2E-117 T 31-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 AF_2287 de1d43e930a2dbef9992297bc21c956e 317 PIRSF PIRSF003314 1 317 3.1E-119 T 31-10-2018 IPR011179 Isopentenyl-diphosphate delta-isomerase, FMN-dependent GO:0004452|GO:0005737|GO:0008299|GO:0010181 KEGG: 00900+5.3.3.2|MetaCyc: PWY-5123|MetaCyc: PWY-6174|MetaCyc: PWY-6383|MetaCyc: PWY-6859|MetaCyc: PWY-7102|MetaCyc: PWY-7391|MetaCyc: PWY-7524|MetaCyc: PWY-7560|MetaCyc: PWY-922 AF_2287 de1d43e930a2dbef9992297bc21c956e 317 SMART SM01240 6 309 0.0028 T 31-10-2018 AF_2100 78588caddb1cbb6cd8a149a2986a3368 575 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 436 455 - T 31-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 AF_2100 78588caddb1cbb6cd8a149a2986a3368 575 Gene3D G3DSA:3.40.50.1220 198 366 7.0E-48 T 31-10-2018 AF_2100 78588caddb1cbb6cd8a149a2986a3368 575 Gene3D G3DSA:3.40.50.970 367 564 1.2E-60 T 31-10-2018 AF_2100 78588caddb1cbb6cd8a149a2986a3368 575 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 399 546 1.3E-39 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AF_2100 78588caddb1cbb6cd8a149a2986a3368 575 Gene3D G3DSA:3.40.50.970 1 184 3.7E-63 T 31-10-2018 AF_2100 78588caddb1cbb6cd8a149a2986a3368 575 SUPERFAMILY SSF52518 1 177 1.09E-51 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold AF_2100 78588caddb1cbb6cd8a149a2986a3368 575 SUPERFAMILY SSF52518 373 556 1.07E-57 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold AF_2100 78588caddb1cbb6cd8a149a2986a3368 575 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 5 172 8.5E-54 T 31-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AF_2100 78588caddb1cbb6cd8a149a2986a3368 575 SUPERFAMILY SSF52467 194 383 1.26E-45 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AF_2100 78588caddb1cbb6cd8a149a2986a3368 575 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 201 335 2.8E-35 T 31-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AF_1846 4470274c76aa851b25b0b6469bfa1677 136 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 23 97 9.6E-18 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal AF_1846 4470274c76aa851b25b0b6469bfa1677 136 Gene3D G3DSA:1.10.10.10 8 126 3.5E-34 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1846 4470274c76aa851b25b0b6469bfa1677 136 SUPERFAMILY SSF46785 27 116 3.74E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1129 b3236b71b24d1fb5d951af8360b79c8f 135 Gene3D G3DSA:3.30.230.10 1 135 8.5E-48 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AF_1129 b3236b71b24d1fb5d951af8360b79c8f 135 ProSitePatterns PS00360 Ribosomal protein S9 signature. 70 88 - T 31-10-2018 IPR020574 Ribosomal protein S9, conserved site GO:0003735|GO:0005840|GO:0006412 AF_1129 b3236b71b24d1fb5d951af8360b79c8f 135 TIGRFAM TIGR03627 uS9_arch: ribosomal protein uS9 6 135 1.8E-63 T 31-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1129 b3236b71b24d1fb5d951af8360b79c8f 135 Pfam PF00380 Ribosomal protein S9/S16 11 135 3.7E-30 T 31-10-2018 IPR000754 Ribosomal protein S9 GO:0003735|GO:0005840|GO:0006412 AF_1129 b3236b71b24d1fb5d951af8360b79c8f 135 SUPERFAMILY SSF54211 6 135 7.59E-35 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AF_1129 b3236b71b24d1fb5d951af8360b79c8f 135 Hamap MF_00532_A 30S ribosomal protein S9 [rpsI]. 6 135 35.704 T 31-10-2018 IPR019958 Ribosomal protein S9, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_0669 2df377dfdf89aa42c2751d1969295ba0 63 Gene3D G3DSA:3.30.429.10 2 63 1.5E-20 T 31-10-2018 IPR014347 Tautomerase/MIF superfamily AF_0669 2df377dfdf89aa42c2751d1969295ba0 63 TIGRFAM TIGR00013 taut: 4-oxalocrotonate tautomerase family enzyme 1 62 4.1E-23 T 31-10-2018 IPR018191 4-oxalocrotonate tautomerase, Pseudomonas-type GO:0006725|GO:0016853 AF_0669 2df377dfdf89aa42c2751d1969295ba0 63 Pfam PF01361 Tautomerase enzyme 2 60 1.4E-15 T 31-10-2018 IPR004370 4-oxalocrotonate tautomerase GO:0006725|GO:0016853 AF_0669 2df377dfdf89aa42c2751d1969295ba0 63 SUPERFAMILY SSF55331 5 60 2.26E-10 T 31-10-2018 IPR014347 Tautomerase/MIF superfamily AF_0988 c352ec4904bf32aa576a11e7969c3dc4 347 Gene3D G3DSA:3.40.190.10 127 263 8.5E-30 T 31-10-2018 AF_0988 c352ec4904bf32aa576a11e7969c3dc4 347 SUPERFAMILY SSF53850 38 337 8.93E-31 T 31-10-2018 AF_0988 c352ec4904bf32aa576a11e7969c3dc4 347 Gene3D G3DSA:3.40.190.10 46 335 8.5E-30 T 31-10-2018 AF_0988 c352ec4904bf32aa576a11e7969c3dc4 347 Pfam PF16868 NMT1-like family 75 335 7.8E-18 T 31-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family AF_1988 edfd6736f56db88591e9f90a6d9f8866 175 SUPERFAMILY SSF55154 1 165 5.89E-38 T 31-10-2018 IPR033469 CYTH-like domain superfamily Reactome: R-HSA-196819 AF_1988 edfd6736f56db88591e9f90a6d9f8866 175 Pfam PF01928 CYTH domain 2 161 4.1E-34 T 31-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 AF_1988 edfd6736f56db88591e9f90a6d9f8866 175 ProDom PD009560 CYCLASE ADENYLATE CYCLASE ADENYLYL CYAB LYASE CLASS CYAB-TYPE THERMOPHILIC MJ0240 2 142 1.0E-74 T 31-10-2018 AF_1988 edfd6736f56db88591e9f90a6d9f8866 175 SMART SM01118 1 167 2.4E-25 T 31-10-2018 IPR023577 CYTH domain Reactome: R-HSA-196819 AF_1988 edfd6736f56db88591e9f90a6d9f8866 175 TIGRFAM TIGR00318 cyaB: putative adenylyl cyclase CyaB 1 166 1.5E-71 T 31-10-2018 IPR008173 Adenylyl cyclase CyaB KEGG: 00230+4.6.1.1 AF_1988 edfd6736f56db88591e9f90a6d9f8866 175 Gene3D G3DSA:2.40.320.10 1 173 3.2E-46 T 31-10-2018 AF_1748 737cb5d6b78486c4dee2396ed850df24 236 SMART SM00849 20 199 7.3E-32 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_1748 737cb5d6b78486c4dee2396ed850df24 236 Pfam PF00753 Metallo-beta-lactamase superfamily 17 199 9.4E-38 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_1748 737cb5d6b78486c4dee2396ed850df24 236 Gene3D G3DSA:3.60.15.10 2 231 6.3E-49 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_1748 737cb5d6b78486c4dee2396ed850df24 236 SUPERFAMILY SSF56281 4 217 1.27E-47 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_0932 230380802fe496db55b42fac12ffacdc 666 Gene3D G3DSA:3.30.470.20 4 204 3.9E-73 T 31-10-2018 AF_0932 230380802fe496db55b42fac12ffacdc 666 SUPERFAMILY SSF51735 213 352 1.25E-38 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0932 230380802fe496db55b42fac12ffacdc 666 Gene3D G3DSA:3.40.50.261 347 507 9.5E-46 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_0932 230380802fe496db55b42fac12ffacdc 666 Pfam PF13380 CoA binding domain 226 350 2.1E-27 T 31-10-2018 IPR003781 CoA-binding GO:0048037 AF_0932 230380802fe496db55b42fac12ffacdc 666 SUPERFAMILY SSF52210 511 661 4.45E-23 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_0932 230380802fe496db55b42fac12ffacdc 666 SUPERFAMILY SSF52210 348 506 1.7E-36 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_0932 230380802fe496db55b42fac12ffacdc 666 Pfam PF13549 ATP-grasp domain 2 206 3.3E-64 T 31-10-2018 AF_0932 230380802fe496db55b42fac12ffacdc 666 Gene3D G3DSA:3.40.50.720 219 346 5.0E-44 T 31-10-2018 AF_0932 230380802fe496db55b42fac12ffacdc 666 SUPERFAMILY SSF56059 4 209 2.65E-43 T 31-10-2018 AF_0932 230380802fe496db55b42fac12ffacdc 666 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 370 502 7.8E-44 T 31-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain AF_0932 230380802fe496db55b42fac12ffacdc 666 Gene3D G3DSA:3.30.1490.20 22 92 3.9E-73 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AF_0932 230380802fe496db55b42fac12ffacdc 666 Gene3D G3DSA:3.40.50.261 510 665 6.3E-24 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_0932 230380802fe496db55b42fac12ffacdc 666 SMART SM00881 222 316 5.5E-37 T 31-10-2018 IPR003781 CoA-binding GO:0048037 AF_0713 2d3b7dae295c5bd7dc72bc624a158e7e 223 Gene3D G3DSA:3.20.20.70 1 220 1.7E-26 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0713 2d3b7dae295c5bd7dc72bc624a158e7e 223 SUPERFAMILY SSF51366 1 219 8.01E-22 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AF_0713 2d3b7dae295c5bd7dc72bc624a158e7e 223 Pfam PF00977 Histidine biosynthesis protein 3 213 1.7E-15 T 31-10-2018 IPR006062 Histidine biosynthesis GO:0000105 AF_0713 2d3b7dae295c5bd7dc72bc624a158e7e 223 TIGRFAM TIGR00734 hisAF_rel: hisA/hisF family protein 1 213 3.9E-99 T 31-10-2018 IPR004650 HisA/HisF-like protein AF_0861 283db15aa6a4591277ba714e66d936e5 432 SUPERFAMILY SSF51366 1 212 2.95E-42 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AF_0861 283db15aa6a4591277ba714e66d936e5 432 SMART SM00934 5 206 2.5E-37 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AF_0861 283db15aa6a4591277ba714e66d936e5 432 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 6 205 5.9E-23 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AF_0861 283db15aa6a4591277ba714e66d936e5 432 Gene3D G3DSA:3.20.20.70 5 211 1.3E-68 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0861 283db15aa6a4591277ba714e66d936e5 432 SUPERFAMILY SSF89562 235 396 1.44E-45 T 31-10-2018 IPR036704 Ribonuclease E inhibitor RraA/RraA-like superfamily AF_0861 283db15aa6a4591277ba714e66d936e5 432 PIRSF PIRSF037137 1 432 3.2E-241 T 31-10-2018 IPR017120 Bifunctional 3-hexulose-6-phosphate synthase/demethylmenaquinone methyltransferase, predicted KEGG: 00030+4.1.2.43|KEGG: 00680+4.1.2.43|MetaCyc: PWY-1861|MetaCyc: PWY-7796 AF_0861 283db15aa6a4591277ba714e66d936e5 432 Pfam PF03737 Aldolase/RraA 239 385 1.3E-43 T 31-10-2018 IPR005493 Ribonuclease E inhibitor RraA/RraA-like protein AF_0861 283db15aa6a4591277ba714e66d936e5 432 Gene3D G3DSA:3.50.30.40 235 394 1.2E-46 T 31-10-2018 AF_0025 94165a845838f516d1eefaffad0e29ea 393 Gene3D G3DSA:1.20.1250.20 1 192 1.2E-25 T 31-10-2018 AF_0025 94165a845838f516d1eefaffad0e29ea 393 Gene3D G3DSA:1.20.1250.20 198 391 3.4E-17 T 31-10-2018 AF_0025 94165a845838f516d1eefaffad0e29ea 393 Pfam PF07690 Major Facilitator Superfamily 19 353 2.0E-35 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AF_0025 94165a845838f516d1eefaffad0e29ea 393 SUPERFAMILY SSF103473 4 390 1.1E-47 T 31-10-2018 IPR036259 MFS transporter superfamily AF_1586 5a04413729ac43343648c2d610140816 109 Pfam PF01909 Nucleotidyltransferase domain 23 98 1.8E-10 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AF_1586 5a04413729ac43343648c2d610140816 109 Gene3D G3DSA:3.30.460.10 19 109 1.9E-17 T 31-10-2018 AF_1586 5a04413729ac43343648c2d610140816 109 SUPERFAMILY SSF81301 23 106 8.88E-16 T 31-10-2018 AF_1165 e441e8767b09eb4d2a3949c686aa727b 101 Pfam PF01990 ATP synthase (F/14-kDa) subunit 5 93 1.3E-17 T 31-10-2018 IPR008218 ATPase, V1 complex, subunit F GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AF_1165 e441e8767b09eb4d2a3949c686aa727b 101 Gene3D G3DSA:3.40.50.10580 1 94 1.2E-28 T 31-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AF_1165 e441e8767b09eb4d2a3949c686aa727b 101 SUPERFAMILY SSF159468 4 100 9.42E-23 T 31-10-2018 IPR036906 ATPase, V1 complex, subunit F superfamily GO:0034220 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AF_1165 e441e8767b09eb4d2a3949c686aa727b 101 Hamap MF_00312 V-type ATP synthase subunit F [atpF]. 2 100 26.068 T 31-10-2018 IPR022944 ATPase, V1 complex, subunit F, bacterial/archaeal AF_1255 c7062aaff3711cea89c9214fdfb5e12b 307 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 148 297 6.5E-59 T 31-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 AF_1255 c7062aaff3711cea89c9214fdfb5e12b 307 TIGRFAM TIGR00658 orni_carb_tr: ornithine carbamoyltransferase 2 300 3.5E-146 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AF_1255 c7062aaff3711cea89c9214fdfb5e12b 307 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 2 142 7.5E-53 T 31-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 AF_1255 c7062aaff3711cea89c9214fdfb5e12b 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 265 288 5.1E-29 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AF_1255 c7062aaff3711cea89c9214fdfb5e12b 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 253 262 5.1E-29 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AF_1255 c7062aaff3711cea89c9214fdfb5e12b 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 47 66 5.1E-29 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AF_1255 c7062aaff3711cea89c9214fdfb5e12b 307 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 129 140 5.1E-29 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AF_1255 c7062aaff3711cea89c9214fdfb5e12b 307 Gene3D G3DSA:3.40.50.1370 132 296 8.5E-128 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AF_1255 c7062aaff3711cea89c9214fdfb5e12b 307 Gene3D G3DSA:3.40.50.1370 2 131 8.5E-128 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AF_1255 c7062aaff3711cea89c9214fdfb5e12b 307 Hamap MF_01109 Ornithine carbamoyltransferase, catabolic [argI]. 1 301 84.296 T 31-10-2018 IPR024904 Ornithine carbamoyltransferase GO:0004585|GO:0006591 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400 AF_1255 c7062aaff3711cea89c9214fdfb5e12b 307 SUPERFAMILY SSF53671 1 302 7.07E-114 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AF_1255 c7062aaff3711cea89c9214fdfb5e12b 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 279 290 2.3E-30 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AF_1255 c7062aaff3711cea89c9214fdfb5e12b 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 217 227 2.3E-30 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AF_1255 c7062aaff3711cea89c9214fdfb5e12b 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 45 59 2.3E-30 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AF_1255 c7062aaff3711cea89c9214fdfb5e12b 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 118 132 2.3E-30 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AF_1255 c7062aaff3711cea89c9214fdfb5e12b 307 PRINTS PR00102 Ornithine carbamoyltransferase signature 78 91 2.3E-30 T 31-10-2018 IPR002292 Ornithine/putrescine carbamoyltransferase GO:0016743 KEGG: 00220+2.1.3.3|MetaCyc: PWY-4981|MetaCyc: PWY-4984|MetaCyc: PWY-7400|Reactome: R-HSA-1268020|Reactome: R-HSA-70635 AF_0457 a329634dd38edb5bd4f966be6363cbff 199 SUPERFAMILY SSF55718 95 187 3.3E-6 T 31-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AF_0457 a329634dd38edb5bd4f966be6363cbff 199 Gene3D G3DSA:3.30.1050.10 93 199 1.0E-8 T 31-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AF_0457 a329634dd38edb5bd4f966be6363cbff 199 Pfam PF02036 SCP-2 sterol transfer family 99 198 1.4E-12 T 31-10-2018 IPR003033 SCP2 sterol-binding domain AF_1737 d5fcd7cf50b0b64a770c6aaaa48b28cd 642 Gene3D G3DSA:3.40.30.10 2 171 1.3E-74 T 31-10-2018 AF_1737 d5fcd7cf50b0b64a770c6aaaa48b28cd 642 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 426 506 0.048 T 31-10-2018 AF_1737 d5fcd7cf50b0b64a770c6aaaa48b28cd 642 Pfam PF07221 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) 205 315 0.069 T 31-10-2018 AF_1737 d5fcd7cf50b0b64a770c6aaaa48b28cd 642 SUPERFAMILY SSF52833 3 129 5.3E-36 T 31-10-2018 IPR036249 Thioredoxin-like superfamily AF_1737 d5fcd7cf50b0b64a770c6aaaa48b28cd 642 PIRSF PIRSF006402 1 620 6.7E-232 T 31-10-2018 IPR024705 Spermatogenesis-associated protein 20 AF_1737 d5fcd7cf50b0b64a770c6aaaa48b28cd 642 Pfam PF03190 Protein of unknown function, DUF255 3 163 2.2E-75 T 31-10-2018 IPR004879 Domain of unknown function DUF255 AF_1737 d5fcd7cf50b0b64a770c6aaaa48b28cd 642 SUPERFAMILY SSF48208 187 525 1.13E-59 T 31-10-2018 IPR008928 Six-hairpin glycosidase superfamily GO:0003824 AF_1737 d5fcd7cf50b0b64a770c6aaaa48b28cd 642 Gene3D G3DSA:1.50.10.20 398 514 2.5E-6 T 31-10-2018 AF_1737 d5fcd7cf50b0b64a770c6aaaa48b28cd 642 Gene3D G3DSA:1.50.10.10 233 327 8.0E-6 T 31-10-2018 IPR012341 Six-hairpin glycosidase-like superfamily GO:0003824 AF_0282 81d87efdb30732a7e0be40a368ff159e 113 ProDom PD020367 UPF0212 RRNAC1165 RRNAC0441 AF0282 VNG1264C MJ0068 PYRAB08340 PH1312 MA1372 TK1194 1 101 2.0E-53 T 31-10-2018 IPR007564 Uncharacterised protein family UPF0212 AF_0282 81d87efdb30732a7e0be40a368ff159e 113 Hamap MF_01223 UPF0212 protein . 1 111 33.955 T 31-10-2018 IPR007564 Uncharacterised protein family UPF0212 AF_0282 81d87efdb30732a7e0be40a368ff159e 113 Pfam PF04475 Protein of unknown function (DUF555) 3 103 1.4E-46 T 31-10-2018 IPR007564 Uncharacterised protein family UPF0212 AF_0282 81d87efdb30732a7e0be40a368ff159e 113 PIRSF PIRSF016934 1 113 4.3E-55 T 31-10-2018 IPR007564 Uncharacterised protein family UPF0212 AF_1305 204a3343b3a9ef95259f0e3835dd39af 394 Pfam PF08714 Formaldehyde-activating enzyme (Fae) 5 162 5.1E-70 T 31-10-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 AF_1305 204a3343b3a9ef95259f0e3835dd39af 394 Gene3D G3DSA:3.30.230.60 1 165 2.4E-69 T 31-10-2018 IPR037075 Formaldehyde-activating enzyme superfamily GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 AF_1305 204a3343b3a9ef95259f0e3835dd39af 394 SUPERFAMILY SSF51366 97 382 1.74E-47 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AF_1305 204a3343b3a9ef95259f0e3835dd39af 394 Gene3D G3DSA:3.20.20.70 175 383 1.5E-58 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1305 204a3343b3a9ef95259f0e3835dd39af 394 SUPERFAMILY SSF54211 2 164 1.14E-67 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AF_1305 204a3343b3a9ef95259f0e3835dd39af 394 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 175 376 3.7E-23 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AF_1305 204a3343b3a9ef95259f0e3835dd39af 394 SMART SM00934 175 377 2.0E-36 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AF_1305 204a3343b3a9ef95259f0e3835dd39af 394 Hamap MF_01268 Bifunctional enzyme Fae/Hps [fae-hps]. 1 394 208.634 T 31-10-2018 IPR020868 Bifunctional enzyme Fae/Hps GO:0016051|GO:0016832|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 AF_1305 204a3343b3a9ef95259f0e3835dd39af 394 TIGRFAM TIGR03126 one_C_fae: formaldehyde-activating enzyme 3 162 4.4E-81 T 31-10-2018 IPR014826 Formaldehyde-activating enzyme GO:0016051|GO:0016840 KEGG: 00030+4.1.2.43|KEGG: 00680+4.2.1.147+4.1.2.43|MetaCyc: PWY-1723|MetaCyc: PWY-1861|MetaCyc: PWY-7796 AF_2195 a9afc388ad597e8fbb6c2c7581396607 301 Pfam PF01916 Deoxyhypusine synthase 16 293 6.2E-97 T 31-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 AF_2195 a9afc388ad597e8fbb6c2c7581396607 301 Hamap MF_00153 Probable deoxyhypusine synthase [dys]. 14 295 42.788 T 31-10-2018 IPR022899 Deoxyhypusine synthase, putative, archaeal GO:0034038 AF_2195 a9afc388ad597e8fbb6c2c7581396607 301 SUPERFAMILY SSF52467 3 298 9.81E-101 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AF_2195 a9afc388ad597e8fbb6c2c7581396607 301 TIGRFAM TIGR00321 dhys: deoxyhypusine synthase 2 296 2.4E-132 T 31-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 AF_2195 a9afc388ad597e8fbb6c2c7581396607 301 Gene3D G3DSA:3.40.910.10 1 301 8.2E-97 T 31-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 AF_0388 1b50d18aa7e803642bc41152e85c12af 306 Pfam PF04055 Radical SAM superfamily 10 163 2.0E-15 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_0388 1b50d18aa7e803642bc41152e85c12af 306 SUPERFAMILY SSF102114 7 267 5.23E-43 T 31-10-2018 AF_0388 1b50d18aa7e803642bc41152e85c12af 306 Gene3D G3DSA:3.20.20.70 2 301 5.8E-49 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0388 1b50d18aa7e803642bc41152e85c12af 306 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 1 302 4.0E-138 T 31-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 AF_0388 1b50d18aa7e803642bc41152e85c12af 306 PIRSF PIRSF004762 1 306 9.4E-101 T 31-10-2018 AF_1350 672763c6d0b7f47007f006df104af773 265 Gene3D G3DSA:3.60.15.10 7 221 1.3E-29 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_1350 672763c6d0b7f47007f006df104af773 265 SUPERFAMILY SSF56281 34 243 3.93E-33 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_1350 672763c6d0b7f47007f006df104af773 265 Pfam PF00753 Metallo-beta-lactamase superfamily 34 163 5.2E-18 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_1350 672763c6d0b7f47007f006df104af773 265 SMART SM00849 24 192 2.0E-24 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_1744 aa40065b87886ae39fc2766c30ae1bee 172 Pfam PF01066 CDP-alcohol phosphatidyltransferase 12 74 7.2E-15 T 31-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AF_1744 aa40065b87886ae39fc2766c30ae1bee 172 Gene3D G3DSA:1.20.120.1760 1 171 5.7E-47 T 31-10-2018 AF_1744 aa40065b87886ae39fc2766c30ae1bee 172 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 52 74 - T 31-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AF_1866 453d86ebc04c8e79038111c74aeb7180 341 Gene3D G3DSA:3.30.70.2940 1 86 5.2E-22 T 31-10-2018 AF_1866 453d86ebc04c8e79038111c74aeb7180 341 Gene3D G3DSA:3.30.70.2950 232 341 1.7E-32 T 31-10-2018 AF_1866 453d86ebc04c8e79038111c74aeb7180 341 TIGRFAM TIGR01888 cas_cmr3: CRISPR type III-B/RAMP module-associated protein Cmr3 4 341 1.6E-105 T 31-10-2018 IPR010165 CRISPR-associated protein, TM1793 AF_1866 453d86ebc04c8e79038111c74aeb7180 341 Pfam PF09700 CRISPR-associated protein (Cas_Cmr3) 4 341 6.9E-86 T 31-10-2018 IPR019117 CRISPR-associated protein, Cmr3 AF_0879 8f8c186fc83d635cc921c7d6b52eb8d2 374 SUPERFAMILY SSF52402 164 361 8.82E-49 T 31-10-2018 AF_0879 8f8c186fc83d635cc921c7d6b52eb8d2 374 SMART SM00981 66 153 1.2E-25 T 31-10-2018 IPR004114 THUMP domain GO:0003723 AF_0879 8f8c186fc83d635cc921c7d6b52eb8d2 374 Pfam PF02926 THUMP domain 32 151 2.6E-26 T 31-10-2018 IPR004114 THUMP domain GO:0003723 AF_0879 8f8c186fc83d635cc921c7d6b52eb8d2 374 Pfam PF02568 Thiamine biosynthesis protein (ThiI) 163 358 4.0E-89 T 31-10-2018 IPR020536 Thil, AANH domain GO:0004810 KEGG: 00730+2.8.1.4 AF_0879 8f8c186fc83d635cc921c7d6b52eb8d2 374 TIGRFAM TIGR00342 TIGR00342: tRNA sulfurtransferase ThiI 7 365 9.6E-157 T 31-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 AF_0879 8f8c186fc83d635cc921c7d6b52eb8d2 374 SUPERFAMILY SSF143437 4 161 5.76E-43 T 31-10-2018 AF_0879 8f8c186fc83d635cc921c7d6b52eb8d2 374 Hamap MF_00021 tRNA sulfurtransferase [thiI]. 1 374 132.651 T 31-10-2018 IPR003720 tRNA sulfurtransferase ThiI GO:0005737|GO:0016783|GO:0034227 KEGG: 00730+2.8.1.4 AF_0879 8f8c186fc83d635cc921c7d6b52eb8d2 374 Gene3D G3DSA:3.30.2130.30 2 162 6.5E-53 T 31-10-2018 AF_0879 8f8c186fc83d635cc921c7d6b52eb8d2 374 Gene3D G3DSA:3.40.50.620 163 372 2.5E-70 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_0156 c084b0bc867bc65f3b928057d75ac51e 95 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 13 24 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0156 c084b0bc867bc65f3b928057d75ac51e 95 Gene3D G3DSA:3.30.70.20 24 78 1.2E-6 T 31-10-2018 AF_0156 c084b0bc867bc65f3b928057d75ac51e 95 Gene3D G3DSA:3.30.70.20 1 23 4.0E-6 T 31-10-2018 AF_0156 c084b0bc867bc65f3b928057d75ac51e 95 Pfam PF13237 4Fe-4S dicluster domain 6 54 7.7E-11 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0156 c084b0bc867bc65f3b928057d75ac51e 95 SUPERFAMILY SSF54862 4 63 2.21E-22 T 31-10-2018 AF_0821 b99b0a1f30710472d586e7cd1005e712 381 Gene3D G3DSA:3.20.20.70 100 289 2.9E-62 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0821 b99b0a1f30710472d586e7cd1005e712 381 SUPERFAMILY SSF51690 104 370 1.3E-71 T 31-10-2018 IPR036068 Nicotinate phosphoribosyltransferase-like, C-terminal GO:0004514|GO:0009435 KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381 AF_0821 b99b0a1f30710472d586e7cd1005e712 381 Gene3D G3DSA:3.90.1170.20 1 99 1.3E-35 T 31-10-2018 IPR037128 Quinolinate phosphoribosyl transferase, N-terminal domain superfamily GO:0016763 Reactome: R-HSA-196807 AF_0821 b99b0a1f30710472d586e7cd1005e712 381 PIRSF PIRSF000484 61 374 4.4E-49 T 31-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 AF_0821 b99b0a1f30710472d586e7cd1005e712 381 PIRSF PIRSF000484 1 65 3.6 T 31-10-2018 IPR007229 Nicotinate phosphoribosyltransferase family KEGG: 00760+6.3.4.21|MetaCyc: PWY-5381|Reactome: R-HSA-197264 AF_0821 b99b0a1f30710472d586e7cd1005e712 381 Pfam PF02749 Quinolinate phosphoribosyl transferase, N-terminal domain 37 106 1.0E-5 T 31-10-2018 IPR022412 Quinolinate phosphoribosyl transferase, N-terminal GO:0016763 Reactome: R-HSA-196807 AF_0821 b99b0a1f30710472d586e7cd1005e712 381 SUPERFAMILY SSF54675 2 108 2.75E-32 T 31-10-2018 AF_0821 b99b0a1f30710472d586e7cd1005e712 381 Pfam PF01729 Quinolinate phosphoribosyl transferase, C-terminal domain 108 295 1.4E-47 T 31-10-2018 IPR002638 Quinolinate phosphoribosyl transferase, C-terminal GO:0004514|GO:0009435 Reactome: R-HSA-196807 AF_2295 2017e9c3bda6d3dc49353d1d80a843c3 414 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 70 315 2.9E-18 T 31-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 AF_2295 2017e9c3bda6d3dc49353d1d80a843c3 414 Gene3D G3DSA:3.90.1150.10 4 384 1.7E-100 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AF_2295 2017e9c3bda6d3dc49353d1d80a843c3 414 SUPERFAMILY SSF53383 1 392 4.87E-92 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AF_2295 2017e9c3bda6d3dc49353d1d80a843c3 414 Gene3D G3DSA:3.40.640.10 38 292 1.7E-100 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AF_0756 23a23d84063440ffbd82b54673007db8 322 Pfam PF02833 DHHA2 domain 195 318 2.6E-23 T 31-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AF_0756 23a23d84063440ffbd82b54673007db8 322 Gene3D G3DSA:3.10.310.20 202 322 1.2E-41 T 31-10-2018 IPR038222 DHHA2 domain superfamily KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AF_0756 23a23d84063440ffbd82b54673007db8 322 Hamap MF_00207 Probable manganese-dependent inorganic pyrophosphatase [ppaC]. 4 321 45.326 T 31-10-2018 IPR022934 Manganese-dependent inorganic pyrophosphatase, probable GO:0004427 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AF_0756 23a23d84063440ffbd82b54673007db8 322 SUPERFAMILY SSF64182 5 319 2.88E-75 T 31-10-2018 IPR038763 DHH phosphoesterase superfamily AF_0756 23a23d84063440ffbd82b54673007db8 322 Pfam PF01368 DHH family 5 157 1.9E-27 T 31-10-2018 IPR001667 DDH domain KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AF_0756 23a23d84063440ffbd82b54673007db8 322 SMART SM01131 193 319 8.7E-57 T 31-10-2018 IPR004097 DHHA2 domain GO:0005737|GO:0016462 KEGG: 00190+3.6.1.1|MetaCyc: PWY-7805|MetaCyc: PWY-7807 AF_0756 23a23d84063440ffbd82b54673007db8 322 Gene3D G3DSA:3.90.1640.10 3 200 2.4E-72 T 31-10-2018 AF_0071 6317fd4705be6c29d18290e6e35e50f8 759 SMART SM00487 10 219 2.5E-24 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AF_0071 6317fd4705be6c29d18290e6e35e50f8 759 SMART SM00490 254 339 1.8E-9 T 31-10-2018 IPR001650 Helicase, C-terminal AF_0071 6317fd4705be6c29d18290e6e35e50f8 759 TIGRFAM TIGR01596 cas3_HD: CRISPR-associated endonuclease Cas3-HD 563 748 1.0E-22 T 31-10-2018 IPR006483 CRISPR-associated Cas3-type HD domain AF_0071 6317fd4705be6c29d18290e6e35e50f8 759 Gene3D G3DSA:3.40.50.300 210 453 2.4E-14 T 31-10-2018 AF_0071 6317fd4705be6c29d18290e6e35e50f8 759 Pfam PF01966 HD domain 582 748 2.4E-15 T 31-10-2018 IPR006674 HD domain AF_0071 6317fd4705be6c29d18290e6e35e50f8 759 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 31 373 2.4E-58 T 31-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core AF_0071 6317fd4705be6c29d18290e6e35e50f8 759 Gene3D G3DSA:1.10.3210.30 550 737 4.5E-16 T 31-10-2018 IPR038257 CRISPR-associated Cas3-type HD domain superfamily AF_0071 6317fd4705be6c29d18290e6e35e50f8 759 Pfam PF00271 Helicase conserved C-terminal domain 233 338 1.1E-8 T 31-10-2018 IPR001650 Helicase, C-terminal AF_0071 6317fd4705be6c29d18290e6e35e50f8 759 SUPERFAMILY SSF52540 24 347 2.94E-29 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0071 6317fd4705be6c29d18290e6e35e50f8 759 Gene3D G3DSA:3.40.50.300 2 200 3.4E-24 T 31-10-2018 AF_0071 6317fd4705be6c29d18290e6e35e50f8 759 Pfam PF00270 DEAD/DEAH box helicase 16 182 1.4E-18 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AF_0592 92c4414100f8d51127d1940df7b3bffe 424 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 25 213 8.1E-13 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AF_0592 92c4414100f8d51127d1940df7b3bffe 424 Pfam PF09173 Initiation factor eIF2 gamma, C terminal 339 423 7.3E-33 T 31-10-2018 IPR015256 Translation initiation factor 2, gamma subunit, C-terminal AF_0592 92c4414100f8d51127d1940df7b3bffe 424 Gene3D G3DSA:2.40.30.10 334 424 2.6E-31 T 31-10-2018 AF_0592 92c4414100f8d51127d1940df7b3bffe 424 Pfam PF03144 Elongation factor Tu domain 2 249 327 1.6E-9 T 31-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AF_0592 92c4414100f8d51127d1940df7b3bffe 424 TIGRFAM TIGR03680 eif2g_arch: translation initiation factor 2, gamma subunit 23 424 1.3E-205 T 31-10-2018 IPR022424 Translation initiation factor 2, gamma subunit AF_0592 92c4414100f8d51127d1940df7b3bffe 424 Gene3D G3DSA:2.40.30.10 222 333 2.2E-40 T 31-10-2018 AF_0592 92c4414100f8d51127d1940df7b3bffe 424 Gene3D G3DSA:3.40.50.300 23 221 3.9E-60 T 31-10-2018 AF_0592 92c4414100f8d51127d1940df7b3bffe 424 SUPERFAMILY SSF50465 332 424 3.96E-33 T 31-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal AF_0592 92c4414100f8d51127d1940df7b3bffe 424 SUPERFAMILY SSF50447 221 331 7.28E-35 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AF_0592 92c4414100f8d51127d1940df7b3bffe 424 Hamap MF_00119 Translation initiation factor 2 subunit gamma [eif2g]. 18 424 64.35 T 31-10-2018 IPR022424 Translation initiation factor 2, gamma subunit AF_0592 92c4414100f8d51127d1940df7b3bffe 424 Pfam PF00009 Elongation factor Tu GTP binding domain 26 217 1.6E-28 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_0592 92c4414100f8d51127d1940df7b3bffe 424 SUPERFAMILY SSF52540 7 229 7.66E-48 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0592 92c4414100f8d51127d1940df7b3bffe 424 PRINTS PR00315 GTP-binding elongation factor signature 104 114 2.0E-13 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_0592 92c4414100f8d51127d1940df7b3bffe 424 PRINTS PR00315 GTP-binding elongation factor signature 120 131 2.0E-13 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_0592 92c4414100f8d51127d1940df7b3bffe 424 PRINTS PR00315 GTP-binding elongation factor signature 158 167 2.0E-13 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_0592 92c4414100f8d51127d1940df7b3bffe 424 PRINTS PR00315 GTP-binding elongation factor signature 27 40 2.0E-13 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_2068 fe2131708b4bea3f86963f9c074fa0e0 111 Gene3D G3DSA:1.10.8.140 32 111 1.3E-27 T 31-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 AF_2068 fe2131708b4bea3f86963f9c074fa0e0 111 Pfam PF01984 Double-stranded DNA-binding domain 10 109 2.3E-26 T 31-10-2018 IPR002836 PDCD5-like GO:0003677 AF_2068 fe2131708b4bea3f86963f9c074fa0e0 111 SUPERFAMILY SSF46950 10 110 9.68E-28 T 31-10-2018 IPR036883 PDCD5-like superfamily GO:0003677 AF_2068 fe2131708b4bea3f86963f9c074fa0e0 111 Hamap MF_00026 DNA-binding protein . 5 110 16.795 T 31-10-2018 IPR022889 DNA-binding protein, archaeal AF_2068 fe2131708b4bea3f86963f9c074fa0e0 111 PIRSF PIRSF015730 2 111 2.8E-33 T 31-10-2018 IPR002836 PDCD5-like GO:0003677 AF_2054 b647630214a1f55a6adc69264e818110 82 Gene3D G3DSA:3.30.70.20 3 82 9.6E-13 T 31-10-2018 AF_2054 b647630214a1f55a6adc69264e818110 82 SUPERFAMILY SSF54862 14 81 1.27E-18 T 31-10-2018 AF_2054 b647630214a1f55a6adc69264e818110 82 Pfam PF13187 4Fe-4S dicluster domain 32 76 1.3E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_2054 b647630214a1f55a6adc69264e818110 82 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 33 44 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_2054 b647630214a1f55a6adc69264e818110 82 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 8 82 2.4E-31 T 31-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 AF_1044 861d35fa7423dbcc3223c32e98d54c09 160 Pfam PF01584 CheW-like domain 17 153 2.4E-40 T 31-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AF_1044 861d35fa7423dbcc3223c32e98d54c09 160 Gene3D G3DSA:2.40.50.180 36 146 5.2E-45 T 31-10-2018 AF_1044 861d35fa7423dbcc3223c32e98d54c09 160 Gene3D G3DSA:2.30.30.40 19 145 5.2E-45 T 31-10-2018 AF_1044 861d35fa7423dbcc3223c32e98d54c09 160 SMART SM00260 13 151 1.0E-50 T 31-10-2018 IPR002545 CheW-like domain GO:0006935|GO:0007165 AF_1044 861d35fa7423dbcc3223c32e98d54c09 160 SUPERFAMILY SSF50341 13 155 1.31E-40 T 31-10-2018 IPR036061 CheW-like domain superfamily GO:0006935|GO:0007165 AF_1272 ea04e4c2318c99f82eb11fe1cdeca985 331 Gene3D G3DSA:3.30.200.20 1 100 7.6E-12 T 31-10-2018 AF_1272 ea04e4c2318c99f82eb11fe1cdeca985 331 Hamap MF_00137 Phosphoribosylaminoimidazole-succinocarboxamide synthase [purC]. 1 310 22.369 T 31-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AF_1272 ea04e4c2318c99f82eb11fe1cdeca985 331 Gene3D G3DSA:3.30.470.20 115 264 2.7E-20 T 31-10-2018 AF_1272 ea04e4c2318c99f82eb11fe1cdeca985 331 TIGRFAM TIGR00081 purC: phosphoribosylaminoimidazolesuccinocarboxamide synthase 2 316 4.7E-110 T 31-10-2018 IPR001636 Phosphoribosylaminoimidazole-succinocarboxamide synthase GO:0004639|GO:0006164 KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234 AF_1272 ea04e4c2318c99f82eb11fe1cdeca985 331 SUPERFAMILY SSF56104 2 313 2.16E-49 T 31-10-2018 AF_1272 ea04e4c2318c99f82eb11fe1cdeca985 331 Pfam PF01259 SAICAR synthetase 22 269 1.7E-24 T 31-10-2018 IPR028923 SAICAR synthetase/ADE2, N-terminal KEGG: 00230+6.3.2.6|MetaCyc: PWY-6123|MetaCyc: PWY-6124|MetaCyc: PWY-7234|Reactome: R-HSA-73817 AF_1079 8278916c9c42841952875dbb04f49991 28 Pfam PF01954 Protein of unknown function DUF104 1 27 7.1E-16 T 31-10-2018 IPR008203 Uncharacterised protein family UPF0165 AF_1079 8278916c9c42841952875dbb04f49991 28 Gene3D G3DSA:4.10.1150.10 1 27 1.1E-15 T 31-10-2018 IPR024069 AF2212-like domain superfamily AF_1079 8278916c9c42841952875dbb04f49991 28 SUPERFAMILY SSF141694 1 27 8.63E-13 T 31-10-2018 AF_0548 270ad5ad1c26288fc287b20dfd5b6052 619 Pfam PF03129 Anticodon binding domain 502 596 1.1E-23 T 31-10-2018 IPR004154 Anticodon-binding AF_0548 270ad5ad1c26288fc287b20dfd5b6052 619 PRINTS PR01047 Threonyl-tRNA synthetase signature 317 340 1.4E-31 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AF_0548 270ad5ad1c26288fc287b20dfd5b6052 619 PRINTS PR01047 Threonyl-tRNA synthetase signature 283 311 1.4E-31 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AF_0548 270ad5ad1c26288fc287b20dfd5b6052 619 PRINTS PR01047 Threonyl-tRNA synthetase signature 460 473 1.4E-31 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AF_0548 270ad5ad1c26288fc287b20dfd5b6052 619 PRINTS PR01047 Threonyl-tRNA synthetase signature 495 507 1.4E-31 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AF_0548 270ad5ad1c26288fc287b20dfd5b6052 619 PRINTS PR01047 Threonyl-tRNA synthetase signature 417 445 1.4E-31 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AF_0548 270ad5ad1c26288fc287b20dfd5b6052 619 Gene3D G3DSA:3.30.930.10 191 483 3.1E-60 T 31-10-2018 AF_0548 270ad5ad1c26288fc287b20dfd5b6052 619 SUPERFAMILY SSF52954 493 600 3.17E-27 T 31-10-2018 AF_0548 270ad5ad1c26288fc287b20dfd5b6052 619 Gene3D G3DSA:3.40.50.800 493 602 4.5E-30 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily AF_0548 270ad5ad1c26288fc287b20dfd5b6052 619 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 277 481 8.1E-19 T 31-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_0548 270ad5ad1c26288fc287b20dfd5b6052 619 Pfam PF08915 Archaea-specific editing domain of threonyl-tRNA synthetase 1 131 2.6E-50 T 31-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 AF_0548 270ad5ad1c26288fc287b20dfd5b6052 619 ProDom PD016189 SYNTHETASE LIGASE THREONYL-TRNA AMINOACYL-TRNA NUCLEOTIDE-BINDING BIOSYNTHESIS ATP-BINDING ZINC METAL-BINDING THRRS 1 131 2.0E-70 T 31-10-2018 IPR015011 Threonyl-tRNA synthetase, editing domain, archaea GO:0004829|GO:0005524|GO:0005737|GO:0008270 KEGG: 00970+6.1.1.3 AF_0548 270ad5ad1c26288fc287b20dfd5b6052 619 Hamap MF_00184 Threonine--tRNA ligase [thrS]. 32 596 28.92 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AF_0548 270ad5ad1c26288fc287b20dfd5b6052 619 TIGRFAM TIGR00418 thrS: threonine--tRNA ligase 18 598 2.1E-198 T 31-10-2018 IPR002320 Threonine-tRNA ligase, class IIa GO:0004829|GO:0005524|GO:0005737|GO:0006435 KEGG: 00970+6.1.1.3 AF_0548 270ad5ad1c26288fc287b20dfd5b6052 619 Gene3D G3DSA:3.50.80.10 1 131 4.1E-50 T 31-10-2018 IPR023509 D-aminoacyl-tRNA deacylase-like superfamily AF_0548 270ad5ad1c26288fc287b20dfd5b6052 619 SUPERFAMILY SSF55681 186 509 2.31E-56 T 31-10-2018 AF_0594 18e2eea27cb722316fe50aee09511c6a 85 SUPERFAMILY SSF81301 3 80 3.27E-17 T 31-10-2018 AF_0594 18e2eea27cb722316fe50aee09511c6a 85 Pfam PF01909 Nucleotidyltransferase domain 4 63 2.8E-9 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AF_0594 18e2eea27cb722316fe50aee09511c6a 85 Gene3D G3DSA:3.30.460.10 1 84 2.1E-19 T 31-10-2018 AF_1270 85066415278f9bd89aee8b67d36a89d8 92 Pfam PF01022 Bacterial regulatory protein, arsR family 15 58 7.6E-10 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_1270 85066415278f9bd89aee8b67d36a89d8 92 SMART SM00418 5 84 1.2E-21 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_1270 85066415278f9bd89aee8b67d36a89d8 92 SUPERFAMILY SSF46785 2 89 9.26E-19 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1270 85066415278f9bd89aee8b67d36a89d8 92 Gene3D G3DSA:1.10.10.10 4 91 3.9E-17 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1642 5cb825fcb961bb635ee15cefcaac72b0 409 Gene3D G3DSA:3.30.930.10 1 318 2.3E-100 T 31-10-2018 AF_1642 5cb825fcb961bb635ee15cefcaac72b0 409 Hamap MF_00125 ATP phosphoribosyltransferase regulatory subunit [hisZ]. 15 362 24.716 T 31-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 AF_1642 5cb825fcb961bb635ee15cefcaac72b0 409 PIRSF PIRSF001549 1 409 1.1E-126 T 31-10-2018 IPR004516 Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit GO:0005737 AF_1642 5cb825fcb961bb635ee15cefcaac72b0 409 Pfam PF13393 Histidyl-tRNA synthetase 8 309 4.6E-71 T 31-10-2018 AF_1642 5cb825fcb961bb635ee15cefcaac72b0 409 TIGRFAM TIGR00443 hisZ_biosyn_reg: ATP phosphoribosyltransferase, regulatory subunit 10 313 1.1E-81 T 31-10-2018 IPR004517 ATP phosphoribosyltransferase regulatory subunit GO:0000105|GO:0005737 AF_1642 5cb825fcb961bb635ee15cefcaac72b0 409 SUPERFAMILY SSF55681 3 311 5.77E-85 T 31-10-2018 AF_1642 5cb825fcb961bb635ee15cefcaac72b0 409 Pfam PF03129 Anticodon binding domain 323 409 3.6E-14 T 31-10-2018 IPR004154 Anticodon-binding AF_1642 5cb825fcb961bb635ee15cefcaac72b0 409 Hamap MF_00127 Histidine--tRNA ligase [hisS]. 1 409 30.439 T 31-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 AF_1642 5cb825fcb961bb635ee15cefcaac72b0 409 Gene3D G3DSA:3.40.50.800 320 406 2.0E-21 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily AF_1642 5cb825fcb961bb635ee15cefcaac72b0 409 SUPERFAMILY SSF52954 322 408 7.69E-21 T 31-10-2018 AF_1642 5cb825fcb961bb635ee15cefcaac72b0 409 TIGRFAM TIGR00442 hisS: histidine--tRNA ligase 5 399 2.1E-123 T 31-10-2018 IPR015807 Histidine-tRNA ligase GO:0004821|GO:0005524|GO:0006427 KEGG: 00970+6.1.1.21 AF_2000 c1d5529db0766d2dc455b8756a27ee14 405 SMART SM00997 173 333 2.6E-109 T 31-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AF_2000 c1d5529db0766d2dc455b8756a27ee14 405 Hamap MF_00563 Adenosylhomocysteinase [ahcY]. 1 405 47.753 T 31-10-2018 IPR034373 Adenosylhomocysteinase GO:0004013|GO:0019510|GO:0051287 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041|Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-2408508|Reactome: R-HSA-5578997 AF_2000 c1d5529db0766d2dc455b8756a27ee14 405 SMART SM00996 3 402 7.7E-132 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AF_2000 c1d5529db0766d2dc455b8756a27ee14 405 ProSitePatterns PS00738 S-adenosyl-L-homocysteine hydrolase signature 1. 63 77 - T 31-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AF_2000 c1d5529db0766d2dc455b8756a27ee14 405 PIRSF PIRSF001109 1 405 9.0E-189 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AF_2000 c1d5529db0766d2dc455b8756a27ee14 405 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 195 211 - T 31-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AF_2000 c1d5529db0766d2dc455b8756a27ee14 405 Gene3D G3DSA:3.40.50.1480 2 394 1.0E-174 T 31-10-2018 AF_2000 c1d5529db0766d2dc455b8756a27ee14 405 TIGRFAM TIGR00936 ahcY: adenosylhomocysteinase 2 405 2.0E-208 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AF_2000 c1d5529db0766d2dc455b8756a27ee14 405 Gene3D G3DSA:3.40.50.720 175 333 1.0E-174 T 31-10-2018 AF_2000 c1d5529db0766d2dc455b8756a27ee14 405 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 173 332 3.1E-53 T 31-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AF_2000 c1d5529db0766d2dc455b8756a27ee14 405 SUPERFAMILY SSF52283 3 405 3.0E-97 T 31-10-2018 AF_2000 c1d5529db0766d2dc455b8756a27ee14 405 SUPERFAMILY SSF51735 173 334 4.16E-66 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_2000 c1d5529db0766d2dc455b8756a27ee14 405 Pfam PF05221 S-adenosyl-L-homocysteine hydrolase 126 398 3.1E-31 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AF_1580 9014d87ddc6338d6e67ca3f6fe2dcd40 166 Pfam PF04079 Segregation and condensation complex subunit ScpB 6 151 1.4E-43 T 31-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 AF_1580 9014d87ddc6338d6e67ca3f6fe2dcd40 166 Gene3D G3DSA:1.10.10.10 1 74 1.5E-17 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1580 9014d87ddc6338d6e67ca3f6fe2dcd40 166 SUPERFAMILY SSF46785 79 147 5.89E-18 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1580 9014d87ddc6338d6e67ca3f6fe2dcd40 166 Gene3D G3DSA:1.10.10.10 75 161 6.3E-19 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1580 9014d87ddc6338d6e67ca3f6fe2dcd40 166 PIRSF PIRSF019345 1 165 4.7E-46 T 31-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 AF_1580 9014d87ddc6338d6e67ca3f6fe2dcd40 166 TIGRFAM TIGR00281 TIGR00281: segregation and condensation protein B 2 166 6.3E-64 T 31-10-2018 IPR005234 Chromosome segregation/condensation protein ScpB GO:0051304 AF_1580 9014d87ddc6338d6e67ca3f6fe2dcd40 166 SUPERFAMILY SSF46785 1 76 4.9E-17 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0885 040641c865007a50d8a618c6e1aa437c 461 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 273 459 1.3E-41 T 31-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal AF_0885 040641c865007a50d8a618c6e1aa437c 461 Gene3D G3DSA:1.10.3140.10 1 137 1.5E-35 T 31-10-2018 AF_0885 040641c865007a50d8a618c6e1aa437c 461 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 6 265 8.0E-80 T 31-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal AF_0885 040641c865007a50d8a618c6e1aa437c 461 SUPERFAMILY SSF47203 256 460 1.07E-46 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AF_0885 040641c865007a50d8a618c6e1aa437c 461 Gene3D G3DSA:2.40.110.10 139 266 4.8E-38 T 31-10-2018 AF_0885 040641c865007a50d8a618c6e1aa437c 461 Gene3D G3DSA:1.20.140.10 270 461 2.5E-44 T 31-10-2018 AF_0885 040641c865007a50d8a618c6e1aa437c 461 PIRSF PIRSF000331 1 461 9.7E-144 T 31-10-2018 IPR004925 HpaB/PvcC/4-BUDH AF_0885 040641c865007a50d8a618c6e1aa437c 461 SUPERFAMILY SSF56645 1 265 3.66E-66 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AF_0340 ff616794041709ba51b1d58f41c46544 598 SMART SM00790 4 207 2.7E-118 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 AF_0340 ff616794041709ba51b1d58f41c46544 598 Gene3D G3DSA:3.60.9.10 1 208 2.6E-80 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily AF_0340 ff616794041709ba51b1d58f41c46544 598 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 226 594 4.9E-107 T 31-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 AF_0340 ff616794041709ba51b1d58f41c46544 598 SUPERFAMILY SSF56228 1 207 6.93E-72 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily AF_0340 ff616794041709ba51b1d58f41c46544 598 SUPERFAMILY SSF48310 217 597 7.06E-110 T 31-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 AF_0340 ff616794041709ba51b1d58f41c46544 598 Gene3D G3DSA:1.10.569.10 245 422 5.4E-107 T 31-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 AF_0340 ff616794041709ba51b1d58f41c46544 598 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 203 1.4E-74 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 AF_0340 ff616794041709ba51b1d58f41c46544 598 Gene3D G3DSA:1.10.599.10 243 594 5.4E-107 T 31-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 AF_2351 fcd57e4e6964a7babc40748d78530ddb 139 Pfam PF04033 Domain of unknown function (DUF365) 41 138 3.8E-47 T 31-10-2018 IPR007176 Protein of unknown function DUF365 AF_2351 fcd57e4e6964a7babc40748d78530ddb 139 ProDom PD020174 PH0907 MJECS03 PLASMID PF0569 AF2351 41 139 1.0E-51 T 31-10-2018 IPR007176 Protein of unknown function DUF365 AF_2351 fcd57e4e6964a7babc40748d78530ddb 139 PIRSF PIRSF006031 2 139 8.1E-73 T 31-10-2018 IPR007176 Protein of unknown function DUF365 AF_2351 fcd57e4e6964a7babc40748d78530ddb 139 Gene3D G3DSA:2.30.130.30 1 139 9.5E-70 T 31-10-2018 AF_0211 37868df33502c898831ad9aecf3a185f 393 SUPERFAMILY SSF69754 278 388 8.5E-12 T 31-10-2018 IPR036567 Ribosome hibernation promotion factor-like AF_0211 37868df33502c898831ad9aecf3a185f 393 SMART SM00116 144 192 4.2E-9 T 31-10-2018 IPR000644 CBS domain AF_0211 37868df33502c898831ad9aecf3a185f 393 SMART SM00116 222 269 1.5E-4 T 31-10-2018 IPR000644 CBS domain AF_0211 37868df33502c898831ad9aecf3a185f 393 SMART SM00116 16 66 8.3 T 31-10-2018 IPR000644 CBS domain AF_0211 37868df33502c898831ad9aecf3a185f 393 Pfam PF00571 CBS domain 215 269 6.1E-11 T 31-10-2018 IPR000644 CBS domain AF_0211 37868df33502c898831ad9aecf3a185f 393 Pfam PF00571 CBS domain 137 190 2.5E-11 T 31-10-2018 IPR000644 CBS domain AF_0211 37868df33502c898831ad9aecf3a185f 393 Pfam PF00571 CBS domain 10 63 3.9E-5 T 31-10-2018 IPR000644 CBS domain AF_0211 37868df33502c898831ad9aecf3a185f 393 PIRSF PIRSF036983 5 393 2.5E-129 T 31-10-2018 IPR014651 Uncharacterised conserved protein, 2xCBS, MJ1404 type AF_0211 37868df33502c898831ad9aecf3a185f 393 Gene3D G3DSA:3.10.580.10 87 191 1.8E-20 T 31-10-2018 AF_0211 37868df33502c898831ad9aecf3a185f 393 Gene3D G3DSA:3.10.580.10 5 85 1.3E-5 T 31-10-2018 AF_0211 37868df33502c898831ad9aecf3a185f 393 SUPERFAMILY SSF54631 130 269 3.07E-30 T 31-10-2018 AF_0211 37868df33502c898831ad9aecf3a185f 393 SUPERFAMILY SSF54631 5 134 4.3E-11 T 31-10-2018 AF_0211 37868df33502c898831ad9aecf3a185f 393 Gene3D G3DSA:3.10.580.10 196 285 9.3E-13 T 31-10-2018 AF_0448 770cb818a97b91ee3b104b33412461c3 771 Gene3D G3DSA:3.30.450.20 419 546 1.3E-18 T 31-10-2018 AF_0448 770cb818a97b91ee3b104b33412461c3 771 SMART SM00388 699 757 8.4E-6 T 31-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AF_0448 770cb818a97b91ee3b104b33412461c3 771 SUPERFAMILY SSF55781 122 288 6.54E-25 T 31-10-2018 AF_0448 770cb818a97b91ee3b104b33412461c3 771 Pfam PF13426 PAS domain 432 533 2.8E-11 T 31-10-2018 IPR000014 PAS domain AF_0448 770cb818a97b91ee3b104b33412461c3 771 SUPERFAMILY SSF55781 546 702 9.16E-10 T 31-10-2018 AF_0448 770cb818a97b91ee3b104b33412461c3 771 Gene3D G3DSA:3.30.450.20 286 418 2.2E-24 T 31-10-2018 AF_0448 770cb818a97b91ee3b104b33412461c3 771 SMART SM00091 421 489 2.1E-12 T 31-10-2018 IPR000014 PAS domain AF_0448 770cb818a97b91ee3b104b33412461c3 771 SMART SM00091 298 363 5.6E-12 T 31-10-2018 IPR000014 PAS domain AF_0448 770cb818a97b91ee3b104b33412461c3 771 SMART SM00065 143 294 1.6E-6 T 31-10-2018 IPR003018 GAF domain GO:0005515 AF_0448 770cb818a97b91ee3b104b33412461c3 771 SMART SM00065 563 691 5.4E-4 T 31-10-2018 IPR003018 GAF domain GO:0005515 AF_0448 770cb818a97b91ee3b104b33412461c3 771 Pfam PF00989 PAS fold 299 393 7.2E-14 T 31-10-2018 IPR013767 PAS fold GO:0006355 AF_0448 770cb818a97b91ee3b104b33412461c3 771 SUPERFAMILY SSF55785 315 418 2.09E-19 T 31-10-2018 IPR035965 PAS domain superfamily AF_0448 770cb818a97b91ee3b104b33412461c3 771 Gene3D G3DSA:3.30.450.40 128 285 2.8E-30 T 31-10-2018 IPR029016 GAF-like domain superfamily AF_0448 770cb818a97b91ee3b104b33412461c3 771 Gene3D G3DSA:3.30.450.40 547 691 1.2E-9 T 31-10-2018 IPR029016 GAF-like domain superfamily AF_0448 770cb818a97b91ee3b104b33412461c3 771 Pfam PF13185 GAF domain 141 285 5.5E-22 T 31-10-2018 IPR003018 GAF domain GO:0005515 AF_0448 770cb818a97b91ee3b104b33412461c3 771 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 297 416 4.0E-25 T 31-10-2018 IPR000014 PAS domain AF_0448 770cb818a97b91ee3b104b33412461c3 771 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 417 541 2.4E-19 T 31-10-2018 IPR000014 PAS domain AF_0448 770cb818a97b91ee3b104b33412461c3 771 SUPERFAMILY SSF55785 405 491 1.33E-20 T 31-10-2018 IPR035965 PAS domain superfamily AF_0455 863fca798af520abcb463fcbd2249e94 632 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 2 330 7.5E-71 T 31-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 AF_0455 863fca798af520abcb463fcbd2249e94 632 Gene3D G3DSA:3.50.50.60 471 588 1.3E-75 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0455 863fca798af520abcb463fcbd2249e94 632 Gene3D G3DSA:3.20.20.70 1 369 8.7E-127 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0455 863fca798af520abcb463fcbd2249e94 632 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 375 600 3.9E-34 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AF_0455 863fca798af520abcb463fcbd2249e94 632 Gene3D G3DSA:3.40.50.720 376 626 1.3E-75 T 31-10-2018 AF_0455 863fca798af520abcb463fcbd2249e94 632 SUPERFAMILY SSF51905 354 629 9.06E-50 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0455 863fca798af520abcb463fcbd2249e94 632 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 580 596 1.4E-18 T 31-10-2018 AF_0455 863fca798af520abcb463fcbd2249e94 632 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 377 396 1.4E-18 T 31-10-2018 AF_0455 863fca798af520abcb463fcbd2249e94 632 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 459 477 1.4E-18 T 31-10-2018 AF_0455 863fca798af520abcb463fcbd2249e94 632 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 497 515 1.4E-18 T 31-10-2018 AF_0455 863fca798af520abcb463fcbd2249e94 632 SUPERFAMILY SSF51395 2 362 1.15E-107 T 31-10-2018 AF_0439 629100e154055165852092a753e46e88 165 SUPERFAMILY SSF46785 5 59 6.56E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0439 629100e154055165852092a753e46e88 165 ProSitePatterns PS00519 AsnC-type HTH domain signature. 22 48 - T 31-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site AF_0439 629100e154055165852092a753e46e88 165 Gene3D G3DSA:3.30.70.920 60 161 1.1E-7 T 31-10-2018 AF_0439 629100e154055165852092a753e46e88 165 SMART SM00344 6 117 1.3E-33 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AF_0439 629100e154055165852092a753e46e88 165 Pfam PF13412 Winged helix-turn-helix DNA-binding 6 50 4.0E-9 T 31-10-2018 AF_0439 629100e154055165852092a753e46e88 165 Gene3D G3DSA:1.10.10.10 6 52 3.1E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1701 7d99c6862d2f434aeaf562dd3985ffe7 391 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 262 357 8.7E-29 T 31-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II AF_1701 7d99c6862d2f434aeaf562dd3985ffe7 391 Gene3D G3DSA:3.40.50.970 1 250 6.6E-97 T 31-10-2018 AF_1701 7d99c6862d2f434aeaf562dd3985ffe7 391 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 15 238 9.6E-80 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 AF_1701 7d99c6862d2f434aeaf562dd3985ffe7 391 Gene3D G3DSA:3.40.50.920 254 381 5.1E-36 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AF_1701 7d99c6862d2f434aeaf562dd3985ffe7 391 SUPERFAMILY SSF52922 257 372 1.57E-31 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AF_1701 7d99c6862d2f434aeaf562dd3985ffe7 391 SUPERFAMILY SSF52518 3 248 6.73E-66 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold AF_2186 2900ed318f2cc734076929252d156fb1 380 Gene3D G3DSA:3.30.470.20 1 225 6.7E-78 T 31-10-2018 AF_2186 2900ed318f2cc734076929252d156fb1 380 SUPERFAMILY SSF52210 230 377 4.58E-47 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_2186 2900ed318f2cc734076929252d156fb1 380 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 248 273 - T 31-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_2186 2900ed318f2cc734076929252d156fb1 380 Pfam PF08442 ATP-grasp domain 2 195 2.1E-71 T 31-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AF_2186 2900ed318f2cc734076929252d156fb1 380 Pfam PF00549 CoA-ligase 254 348 4.5E-17 T 31-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_2186 2900ed318f2cc734076929252d156fb1 380 SUPERFAMILY SSF56059 1 228 2.3E-67 T 31-10-2018 AF_2186 2900ed318f2cc734076929252d156fb1 380 Gene3D G3DSA:3.30.1490.20 21 96 6.7E-78 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AF_2186 2900ed318f2cc734076929252d156fb1 380 Gene3D G3DSA:3.40.50.261 231 380 5.2E-49 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_2186 2900ed318f2cc734076929252d156fb1 380 PIRSF PIRSF001554 1 380 7.1E-143 T 31-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AF_2186 2900ed318f2cc734076929252d156fb1 380 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 1 377 3.3E-167 T 31-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AF_2186 2900ed318f2cc734076929252d156fb1 380 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 1 378 40.301 T 31-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AF_1695 244ff1c7bf175470b26a98ffe1d6bd23 294 SUPERFAMILY SSF51735 6 148 5.93E-16 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1695 244ff1c7bf175470b26a98ffe1d6bd23 294 TIGRFAM TIGR00745 apbA_panE: 2-dehydropantoate 2-reductase 5 292 2.7E-90 T 31-10-2018 IPR003710 Ketopantoate reductase ApbA/PanE GO:0005737|GO:0008677|GO:0015940 KEGG: 00770+1.1.1.169|MetaCyc: PWY-6654 AF_1695 244ff1c7bf175470b26a98ffe1d6bd23 294 Pfam PF02558 Ketopantoate reductase PanE/ApbA 7 144 2.4E-32 T 31-10-2018 IPR013332 Ketopantoate reductase, N-terminal domain AF_1695 244ff1c7bf175470b26a98ffe1d6bd23 294 Pfam PF08546 Ketopantoate reductase PanE/ApbA C terminal 171 291 2.2E-36 T 31-10-2018 IPR013752 Ketopantoate reductase, C-terminal domain AF_1695 244ff1c7bf175470b26a98ffe1d6bd23 294 Gene3D G3DSA:1.10.1040.10 171 292 8.3E-41 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AF_1695 244ff1c7bf175470b26a98ffe1d6bd23 294 Gene3D G3DSA:3.40.50.720 5 169 9.2E-43 T 31-10-2018 AF_1695 244ff1c7bf175470b26a98ffe1d6bd23 294 SUPERFAMILY SSF48179 170 291 7.14E-33 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_1694 650660a936abcc30f07c55b16ad7f503 420 SUPERFAMILY SSF52374 2 411 2.59E-77 T 31-10-2018 AF_1694 650660a936abcc30f07c55b16ad7f503 420 Hamap MF_00140_A Tryptophan--tRNA ligase [trpS]. 2 419 47.785 T 31-10-2018 IPR020653 Tryptophan-tRNA ligase, archaea GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AF_1694 650660a936abcc30f07c55b16ad7f503 420 Gene3D G3DSA:1.10.240.10 309 419 4.5E-42 T 31-10-2018 AF_1694 650660a936abcc30f07c55b16ad7f503 420 Pfam PF00579 tRNA synthetases class I (W and Y) 281 402 1.3E-15 T 31-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_1694 650660a936abcc30f07c55b16ad7f503 420 Pfam PF00579 tRNA synthetases class I (W and Y) 60 226 3.2E-22 T 31-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_1694 650660a936abcc30f07c55b16ad7f503 420 Gene3D G3DSA:3.40.50.620 1 233 6.8E-60 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_1694 650660a936abcc30f07c55b16ad7f503 420 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 127 146 1.9E-11 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AF_1694 650660a936abcc30f07c55b16ad7f503 420 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 308 318 1.9E-11 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AF_1694 650660a936abcc30f07c55b16ad7f503 420 PRINTS PR01039 Tryptophanyl-tRNA synthetase signature 203 224 1.9E-11 T 31-10-2018 IPR002306 Tryptophan-tRNA ligase GO:0000166|GO:0004830|GO:0005524|GO:0005737|GO:0006436 KEGG: 00970+6.1.1.2 AF_1298 1831b50ee3fd5366f38729f98a85e456 233 SUPERFAMILY SSF46785 166 232 8.91E-7 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1298 1831b50ee3fd5366f38729f98a85e456 233 Gene3D G3DSA:1.10.10.10 12 107 3.3E-22 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1298 1831b50ee3fd5366f38729f98a85e456 233 Gene3D G3DSA:1.10.10.10 176 233 8.5E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1298 1831b50ee3fd5366f38729f98a85e456 233 SUPERFAMILY SSF46785 11 130 2.52E-23 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1298 1831b50ee3fd5366f38729f98a85e456 233 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 66 81 4.1E-5 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_1298 1831b50ee3fd5366f38729f98a85e456 233 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 51 66 4.1E-5 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_1298 1831b50ee3fd5366f38729f98a85e456 233 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 19 34 4.1E-5 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_1298 1831b50ee3fd5366f38729f98a85e456 233 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 185 225 3.9E-7 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal AF_1298 1831b50ee3fd5366f38729f98a85e456 233 Pfam PF01022 Bacterial regulatory protein, arsR family 25 70 1.0E-14 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_1298 1831b50ee3fd5366f38729f98a85e456 233 SMART SM00418 17 90 2.3E-15 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_1173 5359837bed7e8276f29ed01f80017c46 197 ProDom PD695862 AF1173 AF0136 AF2020 5 182 2.0E-91 T 31-10-2018 AF_2163 90e416d35ba940fe53d0603c44ccf7aa 192 Pfam PF06742 Protein of unknown function (DUF1214) 73 172 1.2E-23 T 31-10-2018 IPR010621 Domain of unknown function DUF1214 AF_2163 90e416d35ba940fe53d0603c44ccf7aa 192 PIRSF PIRSF009471 2 192 9.7E-83 T 31-10-2018 IPR012038 Uncharacterised conserved protein UCP009471 AF_2163 90e416d35ba940fe53d0603c44ccf7aa 192 SUPERFAMILY SSF160935 15 175 1.83E-30 T 31-10-2018 AF_2163 90e416d35ba940fe53d0603c44ccf7aa 192 Gene3D G3DSA:2.60.120.600 28 186 3.9E-16 T 31-10-2018 IPR037049 Domain of unknown function DUF1214, C-terminal domain superfamily AF_0196 825fc9dd870bf90e05a042eaca38556d 540 ProSitePatterns PS00455 Putative AMP-binding domain signature. 171 182 - T 31-10-2018 IPR020845 AMP-binding, conserved site AF_0196 825fc9dd870bf90e05a042eaca38556d 540 SUPERFAMILY SSF56801 8 537 9.16E-126 T 31-10-2018 AF_0196 825fc9dd870bf90e05a042eaca38556d 540 Pfam PF00501 AMP-binding enzyme 18 434 3.1E-88 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_0196 825fc9dd870bf90e05a042eaca38556d 540 Pfam PF13193 AMP-binding enzyme C-terminal domain 444 524 5.8E-16 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AF_0196 825fc9dd870bf90e05a042eaca38556d 540 Gene3D G3DSA:3.40.50.12780 2 429 1.9E-101 T 31-10-2018 AF_0196 825fc9dd870bf90e05a042eaca38556d 540 Gene3D G3DSA:3.30.300.310 430 538 2.7E-32 T 31-10-2018 AF_1424 26a29522e18cdf31281268d5093c2a2e 547 SMART SM00873 93 250 3.2E-26 T 31-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 AF_1424 26a29522e18cdf31281268d5093c2a2e 547 Pfam PF03483 B3/4 domain 95 233 1.5E-13 T 31-10-2018 IPR005146 B3/B4 tRNA-binding domain GO:0003723|GO:0004826 KEGG: 00970+6.1.1.20 AF_1424 26a29522e18cdf31281268d5093c2a2e 547 Gene3D G3DSA:3.50.40.10 74 269 1.6E-68 T 31-10-2018 IPR020825 Phenylalanyl-tRNA synthetase, B3/B4 KEGG: 00970+6.1.1.20 AF_1424 26a29522e18cdf31281268d5093c2a2e 547 SUPERFAMILY SSF55681 336 540 2.68E-46 T 31-10-2018 AF_1424 26a29522e18cdf31281268d5093c2a2e 547 Gene3D G3DSA:3.30.930.10 356 541 1.2E-50 T 31-10-2018 AF_1424 26a29522e18cdf31281268d5093c2a2e 547 Pfam PF03484 tRNA synthetase B5 domain 274 339 5.4E-20 T 31-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AF_1424 26a29522e18cdf31281268d5093c2a2e 547 SMART SM00874 271 339 2.0E-26 T 31-10-2018 IPR005147 tRNA synthetase, B5-domain GO:0000287|GO:0003723|GO:0005524|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AF_1424 26a29522e18cdf31281268d5093c2a2e 547 Hamap MF_00284 Phenylalanine--tRNA ligase beta subunit [pheT]. 1 538 37.819 T 31-10-2018 IPR022918 Phenylalanine-tRNA ligase beta chain 2, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 AF_1424 26a29522e18cdf31281268d5093c2a2e 547 TIGRFAM TIGR00471 pheT_arch: phenylalanine--tRNA ligase, beta subunit 1 541 1.0E-252 T 31-10-2018 IPR004531 Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archae/euk cytosolic GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AF_1424 26a29522e18cdf31281268d5093c2a2e 547 Gene3D G3DSA:3.30.56.10 272 339 9.5E-28 T 31-10-2018 AF_1424 26a29522e18cdf31281268d5093c2a2e 547 SUPERFAMILY SSF46955 7 72 2.47E-9 T 31-10-2018 IPR009061 Putative DNA-binding domain superfamily AF_1424 26a29522e18cdf31281268d5093c2a2e 547 Gene3D G3DSA:3.30.56.10 1 73 3.7E-15 T 31-10-2018 AF_1424 26a29522e18cdf31281268d5093c2a2e 547 SUPERFAMILY SSF46955 271 343 2.11E-19 T 31-10-2018 IPR009061 Putative DNA-binding domain superfamily AF_0345 5b22b89e7b47d23caa0c39b1bec94d30 164 Gene3D G3DSA:3.40.630.30 1 94 6.0E-12 T 31-10-2018 AF_0345 5b22b89e7b47d23caa0c39b1bec94d30 164 SUPERFAMILY SSF55729 9 86 5.89E-10 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase AF_0345 5b22b89e7b47d23caa0c39b1bec94d30 164 Pfam PF14542 GCN5-related N-acetyl-transferase 11 80 5.3E-12 T 31-10-2018 IPR031165 Yjdj-type Gcn5-related N-acetyltransferase AF_0266 0de7c813c4b1a44987458f8cddd719b0 276 SUPERFAMILY SSF103481 36 134 1.07E-16 T 31-10-2018 AF_0266 0de7c813c4b1a44987458f8cddd719b0 276 Pfam PF00892 EamA-like transporter family 3 132 3.2E-25 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AF_0266 0de7c813c4b1a44987458f8cddd719b0 276 Pfam PF00892 EamA-like transporter family 140 273 8.5E-27 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AF_0266 0de7c813c4b1a44987458f8cddd719b0 276 SUPERFAMILY SSF103481 176 275 1.31E-13 T 31-10-2018 AF_0031 94c3be49b8f77f4d9fc45efe6155518e 339 Gene3D G3DSA:3.40.1280.30 87 255 2.9E-5 T 31-10-2018 IPR038459 tRNA methyltransferase TRM10-type domain superfamily AF_0031 94c3be49b8f77f4d9fc45efe6155518e 339 PIRSF PIRSF018978 1 339 2.4E-150 T 31-10-2018 IPR016742 tRNA methyltransferase, archaea GO:0008175|GO:0030488 AF_1611 db7f1552efd25ae53b2a809a440e640b 371 Gene3D G3DSA:1.10.10.10 31 103 3.0E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1611 db7f1552efd25ae53b2a809a440e640b 371 Pfam PF01861 Protein of unknown function DUF43 123 367 1.3E-111 T 31-10-2018 IPR002723 N(4)-bis(aminopropyl)spermidine synthase, C-terminal AF_1611 db7f1552efd25ae53b2a809a440e640b 371 Hamap MF_01947 N(4)-bis(aminopropyl)spermidine synthase [bpsA]. 31 369 42.036 T 31-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 AF_1611 db7f1552efd25ae53b2a809a440e640b 371 Gene3D G3DSA:3.40.50.150 119 343 2.7E-70 T 31-10-2018 AF_1611 db7f1552efd25ae53b2a809a440e640b 371 SUPERFAMILY SSF46785 37 97 1.64E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1611 db7f1552efd25ae53b2a809a440e640b 371 PIRSF PIRSF005895 2 371 4.0E-148 T 31-10-2018 IPR014435 N(4)-bis(aminopropyl)spermidine synthase GO:0006596|GO:0016765 AF_1611 db7f1552efd25ae53b2a809a440e640b 371 SUPERFAMILY SSF53335 178 261 1.16E-7 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_0086 97cb4a08bd3d6504c8469eed7b3c70e0 244 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 72 239 1.3E-21 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AF_0086 97cb4a08bd3d6504c8469eed7b3c70e0 244 Gene3D G3DSA:1.10.3720.10 42 242 6.4E-23 T 31-10-2018 IPR035906 MetI-like superfamily AF_0086 97cb4a08bd3d6504c8469eed7b3c70e0 244 SUPERFAMILY SSF161098 49 229 3.14E-27 T 31-10-2018 IPR035906 MetI-like superfamily AF_0702 1063ebca368b8c2f16c2b604a4c0aad8 260 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 167 185 1.6E-6 T 31-10-2018 AF_0702 1063ebca368b8c2f16c2b604a4c0aad8 260 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 33 52 1.6E-6 T 31-10-2018 AF_0702 1063ebca368b8c2f16c2b604a4c0aad8 260 Hamap MF_00304 Thiamine thiazole synthase [thi4]. 8 259 43.935 T 31-10-2018 IPR022828 Thiazole biosynthetic enzyme, prokaryotic AF_0702 1063ebca368b8c2f16c2b604a4c0aad8 260 SUPERFAMILY SSF51905 4 257 5.77E-44 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0702 1063ebca368b8c2f16c2b604a4c0aad8 260 Pfam PF01946 Thi4 family 14 240 2.9E-94 T 31-10-2018 AF_0702 1063ebca368b8c2f16c2b604a4c0aad8 260 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 170 179 1.6E-6 T 31-10-2018 AF_0702 1063ebca368b8c2f16c2b604a4c0aad8 260 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 32 54 1.6E-6 T 31-10-2018 AF_0702 1063ebca368b8c2f16c2b604a4c0aad8 260 Gene3D G3DSA:3.50.50.60 5 260 2.3E-92 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0702 1063ebca368b8c2f16c2b604a4c0aad8 260 TIGRFAM TIGR00292 TIGR00292: thiazole biosynthesis enzyme 10 259 2.8E-123 T 31-10-2018 IPR002922 Thiazole biosynthetic enzyme Thi4 family AF_0876 2680673c4e3a8a7d249b22c2ca384901 584 Gene3D G3DSA:3.60.21.10 19 299 9.2E-75 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like AF_0876 2680673c4e3a8a7d249b22c2ca384901 584 ProSitePatterns PS00785 5'-nucleotidase signature 1. 24 36 - T 31-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AF_0876 2680673c4e3a8a7d249b22c2ca384901 584 Pfam PF02872 5'-nucleotidase, C-terminal domain 319 483 3.7E-22 T 31-10-2018 IPR008334 5'-Nucleotidase, C-terminal GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AF_0876 2680673c4e3a8a7d249b22c2ca384901 584 PRINTS PR01607 Apyrase family signature 22 40 1.2E-17 T 31-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AF_0876 2680673c4e3a8a7d249b22c2ca384901 584 PRINTS PR01607 Apyrase family signature 191 208 1.2E-17 T 31-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AF_0876 2680673c4e3a8a7d249b22c2ca384901 584 PRINTS PR01607 Apyrase family signature 210 233 1.2E-17 T 31-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AF_0876 2680673c4e3a8a7d249b22c2ca384901 584 PRINTS PR01607 Apyrase family signature 239 259 1.2E-17 T 31-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AF_0876 2680673c4e3a8a7d249b22c2ca384901 584 PRINTS PR01607 Apyrase family signature 467 486 1.2E-17 T 31-10-2018 IPR006179 5'-Nucleotidase/apyrase GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AF_0876 2680673c4e3a8a7d249b22c2ca384901 584 SUPERFAMILY SSF55816 313 541 3.79E-19 T 31-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AF_0876 2680673c4e3a8a7d249b22c2ca384901 584 Gene3D G3DSA:3.90.780.10 308 486 3.4E-19 T 31-10-2018 IPR036907 5'-Nucleotidase, C-terminal domain superfamily GO:0009166|GO:0016787 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AF_0876 2680673c4e3a8a7d249b22c2ca384901 584 ProSitePatterns PS00786 5'-nucleotidase signature 2. 96 107 - T 31-10-2018 IPR006146 5'-Nucleotidase, conserved site GO:0000166|GO:0016788|GO:0046872 Reactome: R-HSA-196807|Reactome: R-HSA-73621|Reactome: R-HSA-74259 AF_0876 2680673c4e3a8a7d249b22c2ca384901 584 SUPERFAMILY SSF56300 20 298 8.54E-70 T 31-10-2018 AF_0876 2680673c4e3a8a7d249b22c2ca384901 584 Pfam PF00149 Calcineurin-like phosphoesterase 25 227 4.3E-16 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AF_2315 00a4e383cdb8fe505b7828b27d3d24de 174 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 174 90.481 T 31-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 AF_2315 00a4e383cdb8fe505b7828b27d3d24de 174 TIGRFAM TIGR01527 arch_NMN_Atrans: nicotinamide-nucleotide adenylyltransferase 2 170 6.3E-94 T 31-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 AF_2315 00a4e383cdb8fe505b7828b27d3d24de 174 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 2 60 8.8E-17 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AF_2315 00a4e383cdb8fe505b7828b27d3d24de 174 Pfam PF01467 Cytidylyltransferase-like 4 137 1.4E-19 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AF_2315 00a4e383cdb8fe505b7828b27d3d24de 174 Gene3D G3DSA:3.40.50.620 1 173 3.9E-51 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_2315 00a4e383cdb8fe505b7828b27d3d24de 174 SUPERFAMILY SSF52374 1 167 3.75E-33 T 31-10-2018 AF_1405 09c72b6585f02a81dc6b3dd1178fb640 154 Gene3D G3DSA:2.30.130.10 68 153 5.8E-31 T 31-10-2018 IPR036974 PUA domain superfamily GO:0003723 AF_1405 09c72b6585f02a81dc6b3dd1178fb640 154 Pfam PF01472 PUA domain 72 144 8.9E-21 T 31-10-2018 IPR002478 PUA domain GO:0003723 AF_1405 09c72b6585f02a81dc6b3dd1178fb640 154 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 41 146 7.2E-46 T 31-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 AF_1405 09c72b6585f02a81dc6b3dd1178fb640 154 PIRSF PIRSF005067 1 153 6.7E-44 T 31-10-2018 IPR016437 MCT-1/Tma20 AF_1405 09c72b6585f02a81dc6b3dd1178fb640 154 SUPERFAMILY SSF88697 71 150 1.99E-21 T 31-10-2018 IPR015947 PUA-like superfamily AF_1405 09c72b6585f02a81dc6b3dd1178fb640 154 SMART SM00359 71 145 4.9E-23 T 31-10-2018 IPR002478 PUA domain GO:0003723 AF_1405 09c72b6585f02a81dc6b3dd1178fb640 154 TIGRFAM TIGR03684 arCOG00985: arCOG04150 universal archaeal PUA-domain protein 3 150 1.6E-53 T 31-10-2018 IPR022430 Conserved hypothetical protein CHP03684 AF_2057 83c368930cb7b216da3b84b11ce73596 409 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 363 382 - T 31-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AF_2057 83c368930cb7b216da3b84b11ce73596 409 PIRSF PIRSF016578 26 407 1.0E-20 T 31-10-2018 AF_2057 83c368930cb7b216da3b84b11ce73596 409 Gene3D G3DSA:1.10.540.10 22 145 4.0E-38 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AF_2057 83c368930cb7b216da3b84b11ce73596 409 SUPERFAMILY SSF47203 255 408 1.37E-59 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AF_2057 83c368930cb7b216da3b84b11ce73596 409 Gene3D G3DSA:1.20.140.10 263 408 1.7E-57 T 31-10-2018 AF_2057 83c368930cb7b216da3b84b11ce73596 409 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 149 244 4.0E-29 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AF_2057 83c368930cb7b216da3b84b11ce73596 409 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 31 142 1.0E-31 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AF_2057 83c368930cb7b216da3b84b11ce73596 409 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 256 404 5.5E-56 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AF_2057 83c368930cb7b216da3b84b11ce73596 409 SUPERFAMILY SSF56645 25 267 1.16E-78 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AF_2057 83c368930cb7b216da3b84b11ce73596 409 Gene3D G3DSA:2.40.110.10 146 262 2.2E-43 T 31-10-2018 AF_0553 099fa50360c9063c701777ef25bd5fb8 267 Gene3D G3DSA:3.40.50.720 2 252 4.2E-86 T 31-10-2018 AF_0553 099fa50360c9063c701777ef25bd5fb8 267 SUPERFAMILY SSF69572 4 247 3.79E-91 T 31-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 AF_0553 099fa50360c9063c701777ef25bd5fb8 267 Pfam PF00899 ThiF family 10 243 1.1E-67 T 31-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 AF_1543 4f1b205e031227811c12e18ae55a641d 271 Gene3D G3DSA:1.50.10.20 1 66 4.0E-7 T 31-10-2018 AF_1543 4f1b205e031227811c12e18ae55a641d 271 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 5 47 7.5E-5 T 31-10-2018 IPR001330 PFTB repeat GO:0003824 AF_1543 4f1b205e031227811c12e18ae55a641d 271 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 231 265 0.047 T 31-10-2018 IPR001330 PFTB repeat GO:0003824 AF_1543 4f1b205e031227811c12e18ae55a641d 271 Pfam PF00432 Prenyltransferase and squalene oxidase repeat 194 221 1.6 T 31-10-2018 IPR001330 PFTB repeat GO:0003824 AF_1543 4f1b205e031227811c12e18ae55a641d 271 PIRSF PIRSF016175 1 271 3.2E-123 T 31-10-2018 IPR016648 Uncharacterised conserved protein UCP016175, prenyltransferase beta-subunit-related AF_1543 4f1b205e031227811c12e18ae55a641d 271 Gene3D G3DSA:1.50.10.20 67 269 5.3E-10 T 31-10-2018 AF_1543 4f1b205e031227811c12e18ae55a641d 271 SUPERFAMILY SSF48239 3 225 7.39E-21 T 31-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid AF_1341 f2750facb57ac799d152d499ddbffaf5 504 Gene3D G3DSA:3.90.1170.30 412 492 2.2E-23 T 31-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1341 f2750facb57ac799d152d499ddbffaf5 504 TIGRFAM TIGR03327 AMP_phos: AMP phosphorylase 3 498 8.1E-241 T 31-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 AF_1341 f2750facb57ac799d152d499ddbffaf5 504 SUPERFAMILY SSF50692 13 56 1.63E-6 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AF_1341 f2750facb57ac799d152d499ddbffaf5 504 Hamap MF_02132 AMP phosphorylase. 1 502 49.002 T 31-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 AF_1341 f2750facb57ac799d152d499ddbffaf5 504 SMART SM00941 423 490 1.4E-20 T 31-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1341 f2750facb57ac799d152d499ddbffaf5 504 Pfam PF00591 Glycosyl transferase family, a/b domain 160 232 8.5E-11 T 31-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1341 f2750facb57ac799d152d499ddbffaf5 504 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 424 487 1.9E-15 T 31-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1341 f2750facb57ac799d152d499ddbffaf5 504 SUPERFAMILY SSF52418 156 403 9.68E-67 T 31-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1341 f2750facb57ac799d152d499ddbffaf5 504 SUPERFAMILY SSF47648 87 154 4.19E-17 T 31-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1341 f2750facb57ac799d152d499ddbffaf5 504 SUPERFAMILY SSF54680 410 485 2.88E-16 T 31-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1341 f2750facb57ac799d152d499ddbffaf5 504 Gene3D G3DSA:2.40.40.20 1 84 5.5E-11 T 31-10-2018 AF_1341 f2750facb57ac799d152d499ddbffaf5 504 Gene3D G3DSA:3.40.1030.10 153 411 8.8E-94 T 31-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1341 f2750facb57ac799d152d499ddbffaf5 504 Pfam PF01568 Molydopterin dinucleotide binding domain 16 58 1.6E-5 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AF_1341 f2750facb57ac799d152d499ddbffaf5 504 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 8 493 5.4E-192 T 31-10-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 AF_1341 f2750facb57ac799d152d499ddbffaf5 504 Pfam PF02885 Glycosyl transferase family, helical bundle domain 90 151 2.5E-13 T 31-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1341 f2750facb57ac799d152d499ddbffaf5 504 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 194 209 - T 31-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1341 f2750facb57ac799d152d499ddbffaf5 504 Gene3D G3DSA:1.20.970.10 85 152 8.6E-22 T 31-10-2018 AF_1341 f2750facb57ac799d152d499ddbffaf5 504 PIRSF PIRSF000478 85 498 6.3E-126 T 31-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1027 a8dd764244ccdc117182f6f52c083290 480 Gene3D G3DSA:2.40.110.10 141 268 8.1E-49 T 31-10-2018 AF_1027 a8dd764244ccdc117182f6f52c083290 480 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 3 266 2.0E-97 T 31-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal AF_1027 a8dd764244ccdc117182f6f52c083290 480 PIRSF PIRSF000331 1 480 7.8E-165 T 31-10-2018 IPR004925 HpaB/PvcC/4-BUDH AF_1027 a8dd764244ccdc117182f6f52c083290 480 Gene3D G3DSA:1.10.3140.10 1 140 1.5E-51 T 31-10-2018 AF_1027 a8dd764244ccdc117182f6f52c083290 480 Gene3D G3DSA:1.20.140.10 270 474 8.6E-70 T 31-10-2018 AF_1027 a8dd764244ccdc117182f6f52c083290 480 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 276 470 1.2E-62 T 31-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal AF_1027 a8dd764244ccdc117182f6f52c083290 480 SUPERFAMILY SSF56645 1 267 3.93E-78 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AF_1027 a8dd764244ccdc117182f6f52c083290 480 SUPERFAMILY SSF47203 257 473 1.46E-62 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AF_1732 2700a81d709efeb1e3c49aaccd6c6679 340 Gene3D G3DSA:3.40.50.720 5 335 3.1E-141 T 31-10-2018 AF_1732 2700a81d709efeb1e3c49aaccd6c6679 340 PIRSF PIRSF000149 2 322 7.2E-92 T 31-10-2018 IPR020831 Glyceraldehyde/Erythrose phosphate dehydrogenase family GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1732 2700a81d709efeb1e3c49aaccd6c6679 340 SUPERFAMILY SSF51735 4 159 2.19E-47 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1732 2700a81d709efeb1e3c49aaccd6c6679 340 TIGRFAM TIGR01546 GAPDH-II_archae: glyceraldehyde-3-phosphate dehydrogenase, type II 6 336 1.5E-144 T 31-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 AF_1732 2700a81d709efeb1e3c49aaccd6c6679 340 Gene3D G3DSA:3.30.360.10 142 307 3.1E-141 T 31-10-2018 AF_1732 2700a81d709efeb1e3c49aaccd6c6679 340 SMART SM00846 4 142 1.2E-21 T 31-10-2018 IPR020828 Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1732 2700a81d709efeb1e3c49aaccd6c6679 340 Pfam PF01113 Dihydrodipicolinate reductase, N-terminus 4 109 3.5E-10 T 31-10-2018 IPR000846 Dihydrodipicolinate reductase, N-terminal GO:0008839|GO:0009089|GO:0055114 KEGG: 00261+1.17.1.8|KEGG: 00300+1.17.1.8|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AF_1732 2700a81d709efeb1e3c49aaccd6c6679 340 Pfam PF02800 Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain 147 300 1.1E-30 T 31-10-2018 IPR020829 Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1732 2700a81d709efeb1e3c49aaccd6c6679 340 SUPERFAMILY SSF55347 142 302 9.0E-51 T 31-10-2018 AF_1732 2700a81d709efeb1e3c49aaccd6c6679 340 Hamap MF_00559 Glyceraldehyde-3-phosphate dehydrogenase [gap]. 1 340 183.77 T 31-10-2018 IPR006436 Glyceraldehyde-3-phosphate dehydrogenase, type II GO:0005737|GO:0006096|GO:0016620|GO:0050661|GO:0051287|GO:0055114 KEGG: 00010+1.2.1.59|KEGG: 00710+1.2.1.59 AF_1732 2700a81d709efeb1e3c49aaccd6c6679 340 ProSitePatterns PS00071 Glyceraldehyde 3-phosphate dehydrogenase active site. 140 147 - T 31-10-2018 IPR020830 Glyceraldehyde 3-phosphate dehydrogenase, active site GO:0016620|GO:0055114 Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_0661 de3616661f3e5c0d32370752adec247c 379 Gene3D G3DSA:1.10.1060.10 14 98 1.1E-5 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_0661 de3616661f3e5c0d32370752adec247c 379 SUPERFAMILY SSF103501 216 372 4.71E-22 T 31-10-2018 IPR036197 NarG-like superfamily AF_0661 de3616661f3e5c0d32370752adec247c 379 SUPERFAMILY SSF46548 19 95 5.58E-15 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_0661 de3616661f3e5c0d32370752adec247c 379 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 66 77 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0661 de3616661f3e5c0d32370752adec247c 379 Pfam PF13534 4Fe-4S dicluster domain 21 79 4.7E-7 T 31-10-2018 AF_0252 756ace707f73a15204829f58ca222f7c 532 Pfam PF06418 CTP synthase N-terminus 2 265 2.5E-125 T 31-10-2018 IPR017456 CTP synthase, N-terminal GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AF_0252 756ace707f73a15204829f58ca222f7c 532 TIGRFAM TIGR00337 PyrG: CTP synthase 1 522 2.0E-260 T 31-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AF_0252 756ace707f73a15204829f58ca222f7c 532 Gene3D G3DSA:3.40.50.880 284 532 3.4E-108 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_0252 756ace707f73a15204829f58ca222f7c 532 SUPERFAMILY SSF52317 287 529 4.14E-83 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_0252 756ace707f73a15204829f58ca222f7c 532 Pfam PF00117 Glutamine amidotransferase class-I 299 521 5.3E-62 T 31-10-2018 IPR017926 Glutamine amidotransferase AF_0252 756ace707f73a15204829f58ca222f7c 532 SUPERFAMILY SSF52540 1 265 4.11E-116 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0252 756ace707f73a15204829f58ca222f7c 532 Hamap MF_01227 CTP synthase [pyrG]. 1 527 51.43 T 31-10-2018 IPR004468 CTP synthase GO:0003883|GO:0006221 KEGG: 00240+6.3.4.2|MetaCyc: PWY-7176|MetaCyc: PWY-7177|MetaCyc: PWY-7185|Reactome: R-HSA-499943 AF_0252 756ace707f73a15204829f58ca222f7c 532 Gene3D G3DSA:3.40.50.300 1 283 1.6E-136 T 31-10-2018 AF_2264 194cc61e9060df924dc9b9ce57292d59 154 TIGRFAM TIGR02286 PaaD: phenylacetic acid degradation protein PaaD 36 146 1.3E-35 T 31-10-2018 IPR011973 Phenylacetic acid degradation protein PaaD GO:0016790 AF_2264 194cc61e9060df924dc9b9ce57292d59 154 SUPERFAMILY SSF54637 18 149 2.44E-28 T 31-10-2018 IPR029069 HotDog domain superfamily AF_2264 194cc61e9060df924dc9b9ce57292d59 154 Pfam PF03061 Thioesterase superfamily 63 136 2.6E-14 T 31-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AF_2264 194cc61e9060df924dc9b9ce57292d59 154 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 32 144 8.2E-39 T 31-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 AF_2264 194cc61e9060df924dc9b9ce57292d59 154 Gene3D G3DSA:3.10.129.10 15 152 2.1E-43 T 31-10-2018 AF_0498 da5e27cc94b4b4a08d5ad13a405c1836 576 Gene3D G3DSA:1.10.540.10 21 132 3.6E-39 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AF_0498 da5e27cc94b4b4a08d5ad13a405c1836 576 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 249 396 5.6E-17 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AF_0498 da5e27cc94b4b4a08d5ad13a405c1836 576 SUPERFAMILY SSF47203 248 403 5.32E-27 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AF_0498 da5e27cc94b4b4a08d5ad13a405c1836 576 Gene3D G3DSA:2.40.110.10 133 245 3.6E-39 T 31-10-2018 AF_0498 da5e27cc94b4b4a08d5ad13a405c1836 576 Gene3D G3DSA:1.20.140.10 246 394 3.6E-39 T 31-10-2018 AF_0498 da5e27cc94b4b4a08d5ad13a405c1836 576 SUPERFAMILY SSF56645 14 214 2.96E-21 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AF_2301 95f1fc1887b880d309bc3cedf08b3cac 186 TIGRFAM TIGR00286 TIGR00286: arginine decarboxylase, pyruvoyl-dependent 30 186 1.7E-76 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AF_2301 95f1fc1887b880d309bc3cedf08b3cac 186 Gene3D G3DSA:3.50.20.10 24 185 2.0E-47 T 31-10-2018 IPR016105 Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AF_2301 95f1fc1887b880d309bc3cedf08b3cac 186 ProDom PD010449 DECARBOXYLASE PYRUVOYL-DEPENDENT ARGININE SUBUNIT ALPHA CONTAINS: BETA PVLARGDC LYA DECARBOX 31 169 3.0E-78 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AF_2301 95f1fc1887b880d309bc3cedf08b3cac 186 Pfam PF01862 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) 32 185 8.2E-56 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AF_2301 95f1fc1887b880d309bc3cedf08b3cac 186 Hamap MF_01404 Pyruvoyl-dependent arginine decarboxylase [pdaD]. 1 186 65.902 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AF_2301 95f1fc1887b880d309bc3cedf08b3cac 186 SUPERFAMILY SSF56271 28 185 1.91E-51 T 31-10-2018 IPR016104 Pyruvoyl-dependent histidine/arginine decarboxylase GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AF_2301 95f1fc1887b880d309bc3cedf08b3cac 186 PIRSF PIRSF005216 28 186 1.2E-60 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AF_1126 22644f9cd2920d925b68d93c035d90a3 151 TIGRFAM TIGR00725 TIGR00725: TIGR00725 family protein 3 146 7.0E-58 T 31-10-2018 IPR005268 Conserved hypothetical protein CHP00725 AF_1126 22644f9cd2920d925b68d93c035d90a3 151 Pfam PF03641 Possible lysine decarboxylase 45 133 4.8E-7 T 31-10-2018 IPR031100 LOG family AF_1126 22644f9cd2920d925b68d93c035d90a3 151 SUPERFAMILY SSF102405 3 145 3.36E-33 T 31-10-2018 AF_1126 22644f9cd2920d925b68d93c035d90a3 151 Gene3D G3DSA:3.40.50.450 2 148 3.3E-36 T 31-10-2018 AF_0689 de3c533587e232082573eea12481a236 190 Pfam PF09851 Short C-terminal domain 160 187 9.6E-11 T 31-10-2018 IPR018649 SHOCT domain AF_0689 de3c533587e232082573eea12481a236 190 Pfam PF14470 Bacterial PH domain 15 108 5.5E-24 T 31-10-2018 IPR039519 YokE-like, PH domain AF_2185 8183036d2a631bd4ff261f4250d2b482 287 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 152 181 - T 31-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site AF_2185 8183036d2a631bd4ff261f4250d2b482 287 SUPERFAMILY SSF52210 123 285 1.13E-49 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_2185 8183036d2a631bd4ff261f4250d2b482 287 Pfam PF00549 CoA-ligase 151 270 1.7E-17 T 31-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_2185 8183036d2a631bd4ff261f4250d2b482 287 Gene3D G3DSA:3.40.50.720 1 123 1.1E-51 T 31-10-2018 AF_2185 8183036d2a631bd4ff261f4250d2b482 287 SUPERFAMILY SSF51735 1 122 1.28E-44 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_2185 8183036d2a631bd4ff261f4250d2b482 287 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 1 287 43.565 T 31-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AF_2185 8183036d2a631bd4ff261f4250d2b482 287 Gene3D G3DSA:3.40.50.261 124 287 6.8E-69 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_2185 8183036d2a631bd4ff261f4250d2b482 287 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 235 248 - T 31-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site AF_2185 8183036d2a631bd4ff261f4250d2b482 287 SMART SM00881 4 100 2.7E-38 T 31-10-2018 IPR003781 CoA-binding GO:0048037 AF_2185 8183036d2a631bd4ff261f4250d2b482 287 PRINTS PR01798 Succinyl-CoA synthase signature 177 195 3.3E-35 T 31-10-2018 AF_2185 8183036d2a631bd4ff261f4250d2b482 287 PRINTS PR01798 Succinyl-CoA synthase signature 239 256 3.3E-35 T 31-10-2018 AF_2185 8183036d2a631bd4ff261f4250d2b482 287 PRINTS PR01798 Succinyl-CoA synthase signature 208 221 3.3E-35 T 31-10-2018 AF_2185 8183036d2a631bd4ff261f4250d2b482 287 PRINTS PR01798 Succinyl-CoA synthase signature 82 99 3.3E-35 T 31-10-2018 AF_2185 8183036d2a631bd4ff261f4250d2b482 287 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 3 287 7.1E-146 T 31-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AF_2185 8183036d2a631bd4ff261f4250d2b482 287 PIRSF PIRSF001553 1 287 3.5E-132 T 31-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AF_2185 8183036d2a631bd4ff261f4250d2b482 287 Pfam PF02629 CoA binding domain 6 99 5.7E-34 T 31-10-2018 IPR003781 CoA-binding GO:0048037 AF_1900 d4345c37017c887dd4541f66416c78d0 180 Gene3D G3DSA:3.40.50.300 1 177 4.8E-45 T 31-10-2018 AF_1900 d4345c37017c887dd4541f66416c78d0 180 Hamap MF_00239 Cytidylate kinase [cmk]. 1 174 48.011 T 31-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 AF_1900 d4345c37017c887dd4541f66416c78d0 180 Pfam PF13238 AAA domain 3 114 3.0E-17 T 31-10-2018 AF_1900 d4345c37017c887dd4541f66416c78d0 180 TIGRFAM TIGR02173 cyt_kin_arch: putative cytidylate kinase 1 171 3.1E-71 T 31-10-2018 IPR011892 Cytidylate kinase, putative GO:0004127|GO:0005524|GO:0006139 KEGG: 00240+2.7.4.25|MetaCyc: PWY-7205 AF_1900 d4345c37017c887dd4541f66416c78d0 180 SUPERFAMILY SSF52540 1 170 2.79E-27 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 SMART SM00388 407 464 0.006 T 31-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 SUPERFAMILY SSF55785 52 160 1.66E-20 T 31-10-2018 IPR035965 PAS domain superfamily AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 Gene3D G3DSA:3.30.450.20 150 274 3.2E-24 T 31-10-2018 AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 Gene3D G3DSA:3.30.450.20 275 392 7.0E-18 T 31-10-2018 AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 Gene3D G3DSA:3.30.450.20 37 149 1.8E-18 T 31-10-2018 AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 SMART SM00086 111 151 5.3 T 31-10-2018 IPR001610 PAC motif AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 SMART SM00086 354 394 17.0 T 31-10-2018 IPR001610 PAC motif AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 SMART SM00086 236 276 12.0 T 31-10-2018 IPR001610 PAC motif AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 SUPERFAMILY SSF55785 275 392 7.25E-17 T 31-10-2018 IPR035965 PAS domain superfamily AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 502 601 2.7E-21 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 PRINTS PR00344 Bacterial sensor protein C-terminal signature 587 600 6.6E-12 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 PRINTS PR00344 Bacterial sensor protein C-terminal signature 535 549 6.6E-12 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 PRINTS PR00344 Bacterial sensor protein C-terminal signature 563 581 6.6E-12 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 Pfam PF08447 PAS fold 185 263 3.3E-14 T 31-10-2018 IPR013655 PAS fold-3 GO:0005515 AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 Pfam PF08447 PAS fold 302 383 3.1E-12 T 31-10-2018 IPR013655 PAS fold-3 GO:0005515 AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 SUPERFAMILY SSF55785 148 274 2.58E-25 T 31-10-2018 IPR035965 PAS domain superfamily AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 277 395 2.4E-20 T 31-10-2018 IPR000014 PAS domain AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 159 281 5.2E-34 T 31-10-2018 IPR000014 PAS domain AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 41 158 3.0E-20 T 31-10-2018 IPR000014 PAS domain AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 Gene3D G3DSA:3.30.565.10 462 600 2.7E-33 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 SMART SM00387 497 603 9.3E-30 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 Gene3D G3DSA:1.10.287.130 415 461 2.7E-33 T 31-10-2018 AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 Pfam PF13426 PAS domain 51 150 3.1E-8 T 31-10-2018 IPR000014 PAS domain AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 SMART SM00091 40 106 7.0E-8 T 31-10-2018 IPR000014 PAS domain AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 SMART SM00091 163 229 6.7E-12 T 31-10-2018 IPR000014 PAS domain AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 SMART SM00091 281 347 4.2E-7 T 31-10-2018 IPR000014 PAS domain AF_2109 e43bc9060e568968ee0762193f7ffbd4 608 SUPERFAMILY SSF55874 463 601 4.85E-30 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_1615 56d37ac4d93d396677fc63f39505684f 321 Gene3D G3DSA:3.20.20.70 3 262 1.6E-31 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1615 56d37ac4d93d396677fc63f39505684f 321 Pfam PF04055 Radical SAM superfamily 9 161 7.2E-12 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_1615 56d37ac4d93d396677fc63f39505684f 321 SUPERFAMILY SSF102114 6 315 3.92E-30 T 31-10-2018 AF_0827 6bf915c90f0ad0134232ca4c7e0f08a2 461 Gene3D G3DSA:3.40.50.2300 30 175 1.0E-22 T 31-10-2018 AF_0827 6bf915c90f0ad0134232ca4c7e0f08a2 461 SUPERFAMILY SSF53822 43 400 1.5E-52 T 31-10-2018 IPR028082 Periplasmic binding protein-like I AF_0827 6bf915c90f0ad0134232ca4c7e0f08a2 461 Gene3D G3DSA:3.40.50.2300 307 403 1.2E-7 T 31-10-2018 AF_0827 6bf915c90f0ad0134232ca4c7e0f08a2 461 Pfam PF13458 Periplasmic binding protein 44 268 4.4E-36 T 31-10-2018 IPR028081 Leucine-binding protein domain AF_0827 6bf915c90f0ad0134232ca4c7e0f08a2 461 Gene3D G3DSA:3.40.50.2300 176 286 2.3E-20 T 31-10-2018 AF_0764 3d5f9b3ad28bf8e10f7130c47a87428c 119 TIGRFAM TIGR03677 eL8_ribo: ribosomal protein eL8 2 118 2.1E-57 T 31-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_0764 3d5f9b3ad28bf8e10f7130c47a87428c 119 SUPERFAMILY SSF55315 1 116 6.77E-40 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like AF_0764 3d5f9b3ad28bf8e10f7130c47a87428c 119 ProSitePatterns PS01082 Ribosomal protein L7Ae signature. 66 83 - T 31-10-2018 IPR004037 Ribosomal protein L7Ae conserved site GO:0042254|GO:1990904 Reactome: R-HSA-6791226 AF_0764 3d5f9b3ad28bf8e10f7130c47a87428c 119 Gene3D G3DSA:3.30.1330.30 1 119 7.8E-43 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like AF_0764 3d5f9b3ad28bf8e10f7130c47a87428c 119 PRINTS PR00884 Ribosomal protein HS6 signature 36 46 8.6E-30 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_0764 3d5f9b3ad28bf8e10f7130c47a87428c 119 PRINTS PR00884 Ribosomal protein HS6 signature 46 57 8.6E-30 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_0764 3d5f9b3ad28bf8e10f7130c47a87428c 119 PRINTS PR00884 Ribosomal protein HS6 signature 2 13 8.6E-30 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_0764 3d5f9b3ad28bf8e10f7130c47a87428c 119 PRINTS PR00884 Ribosomal protein HS6 signature 87 103 8.6E-30 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_0764 3d5f9b3ad28bf8e10f7130c47a87428c 119 PRINTS PR00884 Ribosomal protein HS6 signature 73 83 8.6E-30 T 31-10-2018 IPR000948 Ribosomal protein L7Ae, prokaryotes GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_0764 3d5f9b3ad28bf8e10f7130c47a87428c 119 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 16 104 9.9E-31 T 31-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 AF_0764 3d5f9b3ad28bf8e10f7130c47a87428c 119 Hamap MF_00326 50S ribosomal protein L7Ae [rpl7ae]. 1 118 32.443 T 31-10-2018 IPR022481 Ribosomal protein L7Ae, archaea GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_0764 3d5f9b3ad28bf8e10f7130c47a87428c 119 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 28 42 2.2E-23 T 31-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family AF_0764 3d5f9b3ad28bf8e10f7130c47a87428c 119 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 47 60 2.2E-23 T 31-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family AF_0764 3d5f9b3ad28bf8e10f7130c47a87428c 119 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 73 87 2.2E-23 T 31-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family AF_0764 3d5f9b3ad28bf8e10f7130c47a87428c 119 PRINTS PR00881 Ribosomal protein L7A/RS6 family signature 63 73 2.2E-23 T 31-10-2018 IPR018492 Ribosomal protein L7Ae/L8/Nhp2 family AF_0922 ec9efcdde961cb2aabab1208f380f94b 138 Pfam PF02812 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain 2 54 1.3E-9 T 31-10-2018 IPR006097 Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain GO:0006520|GO:0016491|GO:0055114 Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AF_0922 ec9efcdde961cb2aabab1208f380f94b 138 Gene3D G3DSA:3.40.50.10860 1 70 8.7E-12 T 31-10-2018 AF_0922 ec9efcdde961cb2aabab1208f380f94b 138 SUPERFAMILY SSF53223 1 104 3.52E-16 T 31-10-2018 AF_0922 ec9efcdde961cb2aabab1208f380f94b 138 ProSitePatterns PS00074 Glu / Leu / Phe / Val dehydrogenases active site. 26 39 - T 31-10-2018 IPR033524 Leu/Phe/Val dehydrogenases active site Reactome: R-HSA-2151201|Reactome: R-HSA-70614 AF_2316 e6b8824b2064445386d620b7e7577c2c 518 Pfam PF04055 Radical SAM superfamily 104 262 3.1E-25 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_2316 e6b8824b2064445386d620b7e7577c2c 518 Pfam PF13394 4Fe-4S single cluster domain 105 188 8.6E-7 T 31-10-2018 AF_2316 e6b8824b2064445386d620b7e7577c2c 518 SUPERFAMILY SSF102114 89 377 1.7E-50 T 31-10-2018 AF_2316 e6b8824b2064445386d620b7e7577c2c 518 Gene3D G3DSA:3.20.20.70 88 316 1.3E-37 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_2436 d0f68fe1dbce8dba69b6b31cb36dbe93 167 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 11 165 1.1E-26 T 31-10-2018 IPR013343 CRISPR-associated protein Cas4 AF_2436 d0f68fe1dbce8dba69b6b31cb36dbe93 167 Gene3D G3DSA:3.90.320.10 10 167 1.5E-5 T 31-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal AF_2436 d0f68fe1dbce8dba69b6b31cb36dbe93 167 Pfam PF01930 Domain of unknown function DUF83 11 166 7.7E-54 T 31-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 AF_0281 57efc1bf6f399cf9e692162c531c3b8c 99 Gene3D G3DSA:1.10.10.10 4 93 8.0E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0281 57efc1bf6f399cf9e692162c531c3b8c 99 SUPERFAMILY SSF46785 13 78 1.77E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0114 fc35223b37ce01bfd8da0e7df1df3dc7 89 Gene3D G3DSA:1.10.10.10 1 89 6.9E-30 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0114 fc35223b37ce01bfd8da0e7df1df3dc7 89 SUPERFAMILY SSF46785 10 79 8.74E-15 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0114 fc35223b37ce01bfd8da0e7df1df3dc7 89 ProSitePatterns PS00414 Profilin signature. 1 9 - T 31-10-2018 IPR027310 Profilin conserved site GO:0003779 Reactome: R-HSA-376176|Reactome: R-HSA-5663220 AF_0114 fc35223b37ce01bfd8da0e7df1df3dc7 89 Pfam PF12840 Helix-turn-helix domain 20 71 2.0E-11 T 31-10-2018 AF_1175 59ed2e3521b33841ef1b349aadf536bf 437 SUPERFAMILY SSF56645 12 258 7.46E-45 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AF_1175 59ed2e3521b33841ef1b349aadf536bf 437 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 14 125 2.7E-14 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AF_1175 59ed2e3521b33841ef1b349aadf536bf 437 Gene3D G3DSA:1.10.540.10 11 134 5.1E-20 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AF_1175 59ed2e3521b33841ef1b349aadf536bf 437 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 140 250 8.2E-13 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AF_1175 59ed2e3521b33841ef1b349aadf536bf 437 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 280 416 4.9E-27 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AF_1175 59ed2e3521b33841ef1b349aadf536bf 437 Gene3D G3DSA:1.20.140.10 268 431 1.2E-34 T 31-10-2018 AF_1175 59ed2e3521b33841ef1b349aadf536bf 437 Gene3D G3DSA:2.40.110.10 139 266 2.2E-24 T 31-10-2018 AF_1175 59ed2e3521b33841ef1b349aadf536bf 437 SUPERFAMILY SSF47203 277 422 5.96E-34 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AF_1087 44cad1f41221add361eb04a696f8b3c4 65 Gene3D G3DSA:4.10.1150.10 6 64 3.9E-19 T 31-10-2018 IPR024069 AF2212-like domain superfamily AF_1087 44cad1f41221add361eb04a696f8b3c4 65 Pfam PF01954 Protein of unknown function DUF104 6 61 4.4E-22 T 31-10-2018 IPR008203 Uncharacterised protein family UPF0165 AF_1087 44cad1f41221add361eb04a696f8b3c4 65 SUPERFAMILY SSF141694 6 63 2.22E-16 T 31-10-2018 AF_0923 77fca90fc8c186e5baaf24ac772f374e 58 Gene3D G3DSA:3.30.70.20 28 58 1.5E-10 T 31-10-2018 AF_0923 77fca90fc8c186e5baaf24ac772f374e 58 Pfam PF00037 4Fe-4S binding domain 33 55 2.9E-10 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0923 77fca90fc8c186e5baaf24ac772f374e 58 Pfam PF00037 4Fe-4S binding domain 4 25 4.8E-6 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0923 77fca90fc8c186e5baaf24ac772f374e 58 Gene3D G3DSA:3.30.70.20 2 27 9.7E-6 T 31-10-2018 AF_0923 77fca90fc8c186e5baaf24ac772f374e 58 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 39 50 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0923 77fca90fc8c186e5baaf24ac772f374e 58 SUPERFAMILY SSF54862 3 57 1.61E-17 T 31-10-2018 AF_1254 539846e633d3cb2f8095dd5f76323b8f 179 Gene3D G3DSA:3.40.630.30 19 179 7.1E-30 T 31-10-2018 AF_1254 539846e633d3cb2f8095dd5f76323b8f 179 SUPERFAMILY SSF55729 25 165 4.8E-31 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase AF_1254 539846e633d3cb2f8095dd5f76323b8f 179 Pfam PF00583 Acetyltransferase (GNAT) family 63 158 4.4E-18 T 31-10-2018 IPR000182 GNAT domain AF_1373 c9b93fd78d92e58deeaa1df60eef0de1 293 Gene3D G3DSA:3.40.50.700 2 174 1.3E-31 T 31-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily AF_1373 c9b93fd78d92e58deeaa1df60eef0de1 293 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 12 156 5.6E-26 T 31-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1373 c9b93fd78d92e58deeaa1df60eef0de1 293 SUPERFAMILY SSF56770 3 231 8.77E-47 T 31-10-2018 AF_0033 7a308bdce2faa9e7540376b769064b46 467 SUPERFAMILY SSF53901 150 288 2.46E-12 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0033 7a308bdce2faa9e7540376b769064b46 467 SUPERFAMILY SSF53901 13 163 2.07E-24 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0033 7a308bdce2faa9e7540376b769064b46 467 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 344 375 1.5E-7 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AF_0033 7a308bdce2faa9e7540376b769064b46 467 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 379 448 3.1E-10 T 31-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AF_0033 7a308bdce2faa9e7540376b769064b46 467 Pfam PF08545 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III 103 175 1.3E-10 T 31-10-2018 IPR013751 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III GO:0004315|GO:0006633 KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AF_0033 7a308bdce2faa9e7540376b769064b46 467 Gene3D G3DSA:3.40.47.10 178 295 8.0E-6 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0033 7a308bdce2faa9e7540376b769064b46 467 Gene3D G3DSA:3.40.47.10 14 177 2.3E-29 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0033 7a308bdce2faa9e7540376b769064b46 467 SUPERFAMILY SSF50249 317 448 6.68E-20 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0482 5ed5ad6ab425b0e02dad07aa273b7d04 632 Gene3D G3DSA:3.60.15.10 183 607 1.9E-152 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_0482 5ed5ad6ab425b0e02dad07aa273b7d04 632 Gene3D G3DSA:3.40.50.10890 385 572 1.9E-152 T 31-10-2018 AF_0482 5ed5ad6ab425b0e02dad07aa273b7d04 632 Gene3D G3DSA:3.30.300.20 64 134 2.6E-60 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta AF_0482 5ed5ad6ab425b0e02dad07aa273b7d04 632 SMART SM00849 190 386 1.0E-29 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_0482 5ed5ad6ab425b0e02dad07aa273b7d04 632 Pfam PF10996 Beta-Casp domain 418 542 3.9E-26 T 31-10-2018 IPR022712 Beta-Casp domain AF_0482 5ed5ad6ab425b0e02dad07aa273b7d04 632 SUPERFAMILY SSF54814 86 132 5.62E-5 T 31-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AF_0482 5ed5ad6ab425b0e02dad07aa273b7d04 632 SMART SM01027 417 542 6.3E-57 T 31-10-2018 IPR022712 Beta-Casp domain AF_0482 5ed5ad6ab425b0e02dad07aa273b7d04 632 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 560 623 1.6E-15 T 31-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain AF_0482 5ed5ad6ab425b0e02dad07aa273b7d04 632 SMART SM00322 94 164 1.1E-5 T 31-10-2018 IPR004087 K Homology domain GO:0003676 AF_0482 5ed5ad6ab425b0e02dad07aa273b7d04 632 Pfam PF16661 Metallo-beta-lactamase superfamily domain 195 361 2.5E-12 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_0482 5ed5ad6ab425b0e02dad07aa273b7d04 632 Pfam PF17214 KH domain 3 68 7.4E-25 T 31-10-2018 IPR033769 KH domain, archaeal AF_0482 5ed5ad6ab425b0e02dad07aa273b7d04 632 Gene3D G3DSA:3.30.300.230 10 168 2.6E-60 T 31-10-2018 AF_0482 5ed5ad6ab425b0e02dad07aa273b7d04 632 SUPERFAMILY SSF56281 177 631 2.54E-138 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_0482 5ed5ad6ab425b0e02dad07aa273b7d04 632 TIGRFAM TIGR03675 arCOG00543: arCOG00543 universal archaeal KH-domain/beta-lactamase-domain protein 6 631 0.0 T 31-10-2018 IPR019975 KH-domain/beta-lactamase-domain protein, archaea AF_1910 cd751768ffd1d6fcd9e8d668e0853da3 131 SUPERFAMILY SSF56047 3 131 1.57E-38 T 31-10-2018 IPR035987 Ribosomal protein S8 superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1910 cd751768ffd1d6fcd9e8d668e0853da3 131 ProSitePatterns PS00053 Ribosomal protein S8 signature. 101 118 - T 31-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1910 cd751768ffd1d6fcd9e8d668e0853da3 131 Gene3D G3DSA:3.30.1490.10 71 129 3.2E-26 T 31-10-2018 AF_1910 cd751768ffd1d6fcd9e8d668e0853da3 131 Hamap MF_01302_A 30S ribosomal protein S8 [rpsH]. 3 131 37.423 T 31-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1910 cd751768ffd1d6fcd9e8d668e0853da3 131 Gene3D G3DSA:3.30.1370.30 2 70 4.7E-29 T 31-10-2018 AF_1910 cd751768ffd1d6fcd9e8d668e0853da3 131 Pfam PF00410 Ribosomal protein S8 6 131 1.2E-29 T 31-10-2018 IPR000630 Ribosomal protein S8 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1498 677d5fdc422b3822781286f9e0ccb274 276 SMART SM00849 20 187 9.1E-17 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_1498 677d5fdc422b3822781286f9e0ccb274 276 SUPERFAMILY SSF56281 2 274 4.76E-25 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_1498 677d5fdc422b3822781286f9e0ccb274 276 Gene3D G3DSA:3.60.15.10 1 218 4.2E-20 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_1261 e78fb452fdaa12e5bc13f18c98b68b7c 233 Pfam PF00501 AMP-binding enzyme 71 130 2.4E-17 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_1261 e78fb452fdaa12e5bc13f18c98b68b7c 233 Gene3D G3DSA:3.30.300.310 131 229 3.7E-36 T 31-10-2018 AF_1261 e78fb452fdaa12e5bc13f18c98b68b7c 233 Pfam PF13193 AMP-binding enzyme C-terminal domain 140 214 6.2E-21 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AF_1261 e78fb452fdaa12e5bc13f18c98b68b7c 233 SUPERFAMILY SSF56801 67 226 1.23E-56 T 31-10-2018 AF_1261 e78fb452fdaa12e5bc13f18c98b68b7c 233 Gene3D G3DSA:2.30.38.10 63 130 4.8E-16 T 31-10-2018 AF_0472 a3c419d9166d769e64e4dd2bfecd3b6f 320 SUPERFAMILY SSF89447 11 50 3.66E-6 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily AF_0472 a3c419d9166d769e64e4dd2bfecd3b6f 320 SMART SM00966 8 53 6.6E-10 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AF_0472 a3c419d9166d769e64e4dd2bfecd3b6f 320 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 10 47 2.6E-10 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AF_0472 a3c419d9166d769e64e4dd2bfecd3b6f 320 SUPERFAMILY SSF109755 121 307 1.19E-7 T 31-10-2018 AF_0472 a3c419d9166d769e64e4dd2bfecd3b6f 320 Pfam PF01895 PhoU domain 134 224 5.5E-10 T 31-10-2018 IPR026022 PhoU domain AF_0584 0a5054e5a4c9c7fd834d80f264457b4e 145 SUPERFAMILY SSF54909 62 142 7.37E-11 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel AF_0584 0a5054e5a4c9c7fd834d80f264457b4e 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.6E-13 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_0584 0a5054e5a4c9c7fd834d80f264457b4e 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.6E-13 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_0584 0a5054e5a4c9c7fd834d80f264457b4e 145 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.6E-13 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_0584 0a5054e5a4c9c7fd834d80f264457b4e 145 SUPERFAMILY SSF46785 1 57 1.22E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0584 0a5054e5a4c9c7fd834d80f264457b4e 145 Pfam PF01037 Lrp/AsnC ligand binding domain 72 132 2.6E-9 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AF_0584 0a5054e5a4c9c7fd834d80f264457b4e 145 SMART SM00344 1 104 8.4E-44 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AF_0584 0a5054e5a4c9c7fd834d80f264457b4e 145 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 48 5.9E-15 T 31-10-2018 AF_0584 0a5054e5a4c9c7fd834d80f264457b4e 145 Gene3D G3DSA:1.10.10.10 1 53 1.1E-18 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0584 0a5054e5a4c9c7fd834d80f264457b4e 145 Gene3D G3DSA:3.30.70.920 54 142 2.6E-13 T 31-10-2018 AF_0461 a6b6336db6d4d4f68d849dcd6d130803 251 Gene3D G3DSA:3.40.50.10790 1 153 1.2E-55 T 31-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal AF_0461 a6b6336db6d4d4f68d849dcd6d130803 251 Pfam PF01887 S-adenosyl-l-methionine hydroxide adenosyltransferase 4 242 8.7E-77 T 31-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase AF_0461 a6b6336db6d4d4f68d849dcd6d130803 251 Gene3D G3DSA:2.40.30.90 162 245 3.0E-22 T 31-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal AF_0461 a6b6336db6d4d4f68d849dcd6d130803 251 SUPERFAMILY SSF101852 160 245 1.31E-21 T 31-10-2018 IPR023227 S-adenosyl-l-methionine hydroxide adenosyltransferase, C-terminal AF_0461 a6b6336db6d4d4f68d849dcd6d130803 251 PIRSF PIRSF006779 1 251 1.9E-90 T 31-10-2018 IPR002747 SAM-dependent chlorinase/fluorinase AF_0461 a6b6336db6d4d4f68d849dcd6d130803 251 SUPERFAMILY SSF102522 1 152 1.14E-51 T 31-10-2018 IPR023228 S-adenosyl-l-methionine hydroxide adenosyltransferase, N-terminal AF_1258 82ea5ef3862e506db77c992ec96c1cb7 104 Gene3D G3DSA:3.30.56.30 1 104 5.1E-41 T 31-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AF_1258 82ea5ef3862e506db77c992ec96c1cb7 104 SUPERFAMILY SSF69695 2 102 2.75E-29 T 31-10-2018 IPR036521 Signal recognition particle, subunit SRP19-like superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AF_1258 82ea5ef3862e506db77c992ec96c1cb7 104 Hamap MF_00305 Signal recognition particle 19 kDa protein [srp19]. 5 87 28.784 T 31-10-2018 IPR022938 Signal recognition particle, SRP19 subunit, archaeal-type AF_1258 82ea5ef3862e506db77c992ec96c1cb7 104 Pfam PF01922 SRP19 protein 5 87 1.6E-21 T 31-10-2018 IPR002778 Signal recognition particle, SRP19 subunit GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AF_2095 99d0f97b00a89ba5f809a39b48177f8b 115 TIGRFAM TIGR00283 arch_pth2: peptidyl-tRNA hydrolase 3 114 5.8E-52 T 31-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 AF_2095 99d0f97b00a89ba5f809a39b48177f8b 115 Gene3D G3DSA:3.40.1490.10 1 115 1.7E-47 T 31-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 AF_2095 99d0f97b00a89ba5f809a39b48177f8b 115 Hamap MF_00628 Peptidyl-tRNA hydrolase [pth]. 3 115 31.166 T 31-10-2018 IPR034759 Peptidyl-tRNA hydrolase, archaea GO:0004045 MetaCyc: PWY-6308 AF_2095 99d0f97b00a89ba5f809a39b48177f8b 115 SUPERFAMILY SSF102462 3 114 4.88E-39 T 31-10-2018 IPR023476 Peptidyl-tRNA hydrolase II domain superfamily MetaCyc: PWY-6308 AF_2095 99d0f97b00a89ba5f809a39b48177f8b 115 Pfam PF01981 Peptidyl-tRNA hydrolase PTH2 3 114 3.2E-36 T 31-10-2018 IPR002833 Peptidyl-tRNA hydrolase, PTH2 GO:0004045 MetaCyc: PWY-6308 AF_0652 ff1a6a4263d47699ab72868c68d9ee73 602 Gene3D G3DSA:1.10.10.1960 462 500 9.2E-8 T 31-10-2018 AF_0652 ff1a6a4263d47699ab72868c68d9ee73 602 SMART SM00387 25 146 1.6E-9 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_0652 ff1a6a4263d47699ab72868c68d9ee73 602 Gene3D G3DSA:1.10.8.50 226 301 1.7E-25 T 31-10-2018 AF_0652 ff1a6a4263d47699ab72868c68d9ee73 602 Gene3D G3DSA:3.30.230.10 303 461 7.4E-64 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AF_0652 ff1a6a4263d47699ab72868c68d9ee73 602 SUPERFAMILY SSF46946 226 298 9.06E-8 T 31-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AF_0652 ff1a6a4263d47699ab72868c68d9ee73 602 Gene3D G3DSA:2.60.40.2960 501 601 1.7E-11 T 31-10-2018 AF_0652 ff1a6a4263d47699ab72868c68d9ee73 602 SUPERFAMILY SSF54211 302 466 1.74E-62 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AF_0652 ff1a6a4263d47699ab72868c68d9ee73 602 ProDom PD013790 TOPOISOMERASE ISOMERASE SUBUNIT DNA B VI TYPE II NUCLEOTIDE-BINDING ATP-BINDING 303 484 7.0E-92 T 31-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 AF_0652 ff1a6a4263d47699ab72868c68d9ee73 602 Gene3D G3DSA:3.30.565.10 1 225 2.1E-79 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_0652 ff1a6a4263d47699ab72868c68d9ee73 602 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 29 127 1.8E-13 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_0652 ff1a6a4263d47699ab72868c68d9ee73 602 SUPERFAMILY SSF55874 12 223 9.04E-32 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_0652 ff1a6a4263d47699ab72868c68d9ee73 602 PIRSF PIRSF006553 1 563 7.6E-230 T 31-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AF_0652 ff1a6a4263d47699ab72868c68d9ee73 602 Pfam PF09239 Topoisomerase VI B subunit, transducer 303 465 1.1E-65 T 31-10-2018 IPR015320 DNA topoisomerase VI, subunit B, transducer GO:0003677|GO:0003918|GO:0006265 AF_0652 ff1a6a4263d47699ab72868c68d9ee73 602 Hamap MF_00322 Type 2 DNA topoisomerase 6 subunit B [top6B]. 2 508 32.459 T 31-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AF_0652 ff1a6a4263d47699ab72868c68d9ee73 602 TIGRFAM TIGR01052 top6b: DNA topoisomerase VI, B subunit 3 487 1.2E-230 T 31-10-2018 IPR005734 DNA topoisomerase VI, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AF_0393 b62d7ee7ed07dc89bb32e87a22495fdd 241 Gene3D G3DSA:3.40.50.300 1 237 1.2E-53 T 31-10-2018 AF_0393 b62d7ee7ed07dc89bb32e87a22495fdd 241 SUPERFAMILY SSF52540 1 218 6.63E-53 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0393 b62d7ee7ed07dc89bb32e87a22495fdd 241 SMART SM00382 26 204 3.8E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0393 b62d7ee7ed07dc89bb32e87a22495fdd 241 Pfam PF00005 ABC transporter 18 157 6.6E-27 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_2036 d2aa973b406e19f52e848a05078eae7c 281 Hamap MF_00154 Protoheme IX farnesyltransferase [cyoE]. 3 280 16.592 T 31-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 AF_2036 d2aa973b406e19f52e848a05078eae7c 281 Gene3D G3DSA:1.10.357.140 10 175 2.4E-16 T 31-10-2018 AF_2036 d2aa973b406e19f52e848a05078eae7c 281 TIGRFAM TIGR01473 cyoE_ctaB: protoheme IX farnesyltransferase 5 277 8.7E-87 T 31-10-2018 IPR006369 Protohaem IX farnesyltransferase GO:0008495|GO:0016021|GO:0048034 Reactome: R-HSA-189451 AF_2036 d2aa973b406e19f52e848a05078eae7c 281 Pfam PF01040 UbiA prenyltransferase family 20 265 2.9E-51 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AF_2036 d2aa973b406e19f52e848a05078eae7c 281 ProSitePatterns PS00943 UbiA prenyltransferase family signature. 56 78 - T 31-10-2018 IPR030470 UbiA prenyltransferase conserved site AF_1224 a51eeb9d888e3e8a6ef5625cd9580372 182 TIGRFAM TIGR00295 TIGR00295: TIGR00295 family protein 7 178 2.0E-87 T 31-10-2018 IPR004454 HD-related protein AF_1224 a51eeb9d888e3e8a6ef5625cd9580372 182 Gene3D G3DSA:1.10.3210.10 2 176 1.1E-16 T 31-10-2018 AF_1224 a51eeb9d888e3e8a6ef5625cd9580372 182 Pfam PF01966 HD domain 22 132 1.0E-18 T 31-10-2018 IPR006674 HD domain AF_1224 a51eeb9d888e3e8a6ef5625cd9580372 182 TIGRFAM TIGR00277 HDIG: HDIG domain 17 96 3.7E-21 T 31-10-2018 IPR006675 HDIG domain AF_1224 a51eeb9d888e3e8a6ef5625cd9580372 182 SUPERFAMILY SSF109604 16 169 5.16E-23 T 31-10-2018 AF_1224 a51eeb9d888e3e8a6ef5625cd9580372 182 SMART SM00471 16 142 7.1E-15 T 31-10-2018 IPR003607 HD/PDEase domain AF_1548 3265ea7fe084afd2cb168c8beeea6354 174 Gene3D G3DSA:1.10.150.20 118 174 4.4E-36 T 31-10-2018 AF_1548 3265ea7fe084afd2cb168c8beeea6354 174 Gene3D G3DSA:3.40.1350.10 1 117 6.0E-43 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 AF_1548 3265ea7fe084afd2cb168c8beeea6354 174 Pfam PF04471 Restriction endonuclease 1 92 4.7E-8 T 31-10-2018 IPR007560 Restriction endonuclease type IV, Mrr GO:0003677|GO:0004519|GO:0009307 AF_1548 3265ea7fe084afd2cb168c8beeea6354 174 SUPERFAMILY SSF47794 118 174 5.89E-31 T 31-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 AF_1548 3265ea7fe084afd2cb168c8beeea6354 174 SUPERFAMILY SSF52980 1 110 4.51E-29 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AF_2303 0657f2612f1eb115ebebeea796cd36c4 286 Pfam PF08443 RimK-like ATP-grasp domain 89 283 4.3E-14 T 31-10-2018 IPR013651 ATP-grasp fold, RimK-type Reactome: R-HSA-70614 AF_2303 0657f2612f1eb115ebebeea796cd36c4 286 Gene3D G3DSA:3.30.470.20 173 285 1.8E-21 T 31-10-2018 AF_2303 0657f2612f1eb115ebebeea796cd36c4 286 Gene3D G3DSA:3.40.50.20 9 105 2.2E-5 T 31-10-2018 AF_2303 0657f2612f1eb115ebebeea796cd36c4 286 SUPERFAMILY SSF56059 81 285 6.01E-37 T 31-10-2018 AF_2303 0657f2612f1eb115ebebeea796cd36c4 286 Gene3D G3DSA:3.30.1490.20 106 171 3.8E-7 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AF_0816 d13b272d8f44d199cb7f75f7c3591537 418 Pfam PF03283 Pectinacetylesterase 69 302 5.8E-10 T 31-10-2018 IPR004963 Pectinacetylesterase/NOTUM GO:0016787 Reactome: R-HSA-381426|Reactome: R-HSA-5362798|Reactome: R-HSA-8957275 AF_0816 d13b272d8f44d199cb7f75f7c3591537 418 SUPERFAMILY SSF53474 130 332 7.94E-9 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_2229 feac206680913fe338ae16e69ba9ebaa 458 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 254 443 5.4E-44 T 31-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 AF_2229 feac206680913fe338ae16e69ba9ebaa 458 Gene3D G3DSA:3.40.50.300 11 46 7.3E-7 T 31-10-2018 AF_2229 feac206680913fe338ae16e69ba9ebaa 458 Hamap MF_00027 Hydrogenobyrinate a,c-diamide synthase [cobB]. 8 444 44.497 T 31-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 AF_2229 feac206680913fe338ae16e69ba9ebaa 458 SUPERFAMILY SSF52540 6 201 1.35E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2229 feac206680913fe338ae16e69ba9ebaa 458 Gene3D G3DSA:3.40.50.880 249 458 3.2E-11 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_2229 feac206680913fe338ae16e69ba9ebaa 458 SUPERFAMILY SSF52317 251 452 7.53E-33 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_2229 feac206680913fe338ae16e69ba9ebaa 458 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 11 188 7.2E-20 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AF_2229 feac206680913fe338ae16e69ba9ebaa 458 Gene3D G3DSA:3.40.50.300 48 199 4.4E-19 T 31-10-2018 AF_2229 feac206680913fe338ae16e69ba9ebaa 458 TIGRFAM TIGR00379 cobB: cobyrinic acid a,c-diamide synthase 10 456 1.2E-226 T 31-10-2018 IPR004484 Cobyrinic acid a,c-diamide synthase CbiA GO:0009236|GO:0042242 AF_0572 b242750c8395859b8d48edb80698d815 202 Gene3D G3DSA:3.40.1160.10 1 198 1.7E-14 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AF_0572 b242750c8395859b8d48edb80698d815 202 SUPERFAMILY SSF53633 1 200 2.51E-15 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AF_0572 b242750c8395859b8d48edb80698d815 202 PIRSF PIRSF004857 1 200 6.0E-76 T 31-10-2018 IPR011375 MfnE family KEGG: 00680+2.7.4.31|MetaCyc: PWY-5254 AF_0491 43c6c75452a8ef514a1af11a60c4cf97 234 SUPERFAMILY SSF89895 2 86 1.96E-24 T 31-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily AF_0491 43c6c75452a8ef514a1af11a60c4cf97 234 Pfam PF01172 Shwachman-Bodian-Diamond syndrome (SBDS) protein 7 93 4.3E-22 T 31-10-2018 IPR019783 Ribosome maturation protein SBDS, N-terminal AF_0491 43c6c75452a8ef514a1af11a60c4cf97 234 SUPERFAMILY SSF109728 82 154 9.16E-27 T 31-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily AF_0491 43c6c75452a8ef514a1af11a60c4cf97 234 SUPERFAMILY SSF54980 156 227 3.45E-23 T 31-10-2018 IPR035647 EF-G domain III/V-like AF_0491 43c6c75452a8ef514a1af11a60c4cf97 234 ProSitePatterns PS01267 Uncharacterized protein family UPF0023 signature. 36 55 - T 31-10-2018 IPR018023 Ribosome maturation protein SBDS, conserved site AF_0491 43c6c75452a8ef514a1af11a60c4cf97 234 TIGRFAM TIGR00291 RNA_SBDS: rRNA metabolism protein, SBDS family 1 231 1.2E-120 T 31-10-2018 IPR002140 Ribosome maturation protein Sdo1/SBDS GO:0042256 AF_0491 43c6c75452a8ef514a1af11a60c4cf97 234 Gene3D G3DSA:3.30.70.240 162 234 1.0E-30 T 31-10-2018 AF_0491 43c6c75452a8ef514a1af11a60c4cf97 234 Gene3D G3DSA:1.10.10.900 87 161 3.3E-35 T 31-10-2018 IPR037188 Ribosome maturation protein Sdo1/SBDS, central domain superfamily AF_0491 43c6c75452a8ef514a1af11a60c4cf97 234 Pfam PF09377 SBDS protein C-terminal domain 100 217 1.1E-23 T 31-10-2018 IPR018978 Ribosome maturation protein SBDS, C-terminal GO:0042254 AF_0491 43c6c75452a8ef514a1af11a60c4cf97 234 Gene3D G3DSA:3.30.1250.10 7 86 7.1E-31 T 31-10-2018 IPR036786 Ribosome maturation protein SBDS, N-terminal domain superfamily AF_0305 f9045abcebdf932243ac4ca98c051769 47 Pfam PF09853 Putative transposon-encoded protein (DUF2080) 2 47 1.5E-17 T 31-10-2018 IPR019205 Protein of unknown function DUF2080, transposon-encoded AF_0857 f9045abcebdf932243ac4ca98c051769 47 Pfam PF09853 Putative transposon-encoded protein (DUF2080) 2 47 1.5E-17 T 31-10-2018 IPR019205 Protein of unknown function DUF2080, transposon-encoded AF_0278 f9045abcebdf932243ac4ca98c051769 47 Pfam PF09853 Putative transposon-encoded protein (DUF2080) 2 47 1.5E-17 T 31-10-2018 IPR019205 Protein of unknown function DUF2080, transposon-encoded AF_1673 94a5aface0a450ee56b4a0d3c26829b6 314 Gene3D G3DSA:1.10.287.70 8 85 1.7E-19 T 31-10-2018 AF_1673 94a5aface0a450ee56b4a0d3c26829b6 314 Pfam PF02080 TrkA-C domain 254 309 1.4E-16 T 31-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AF_1673 94a5aface0a450ee56b4a0d3c26829b6 314 Gene3D G3DSA:3.30.70.1450 240 314 1.2E-15 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AF_1673 94a5aface0a450ee56b4a0d3c26829b6 314 Pfam PF07885 Ion channel 13 86 3.0E-18 T 31-10-2018 IPR013099 Potassium channel domain AF_1673 94a5aface0a450ee56b4a0d3c26829b6 314 Pfam PF02254 TrkA-N domain 106 218 1.9E-30 T 31-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AF_1673 94a5aface0a450ee56b4a0d3c26829b6 314 Gene3D G3DSA:3.40.50.720 97 239 3.3E-35 T 31-10-2018 AF_1673 94a5aface0a450ee56b4a0d3c26829b6 314 SUPERFAMILY SSF81324 6 127 3.14E-28 T 31-10-2018 AF_1673 94a5aface0a450ee56b4a0d3c26829b6 314 SUPERFAMILY SSF51735 101 239 2.28E-30 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1673 94a5aface0a450ee56b4a0d3c26829b6 314 SUPERFAMILY SSF116726 249 310 1.57E-15 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AF_0160 536676e52210ffcee5cb484488586321 174 Pfam PF02613 Nitrate reductase delta subunit 71 134 2.7E-11 T 31-10-2018 IPR020945 DMSO/Nitrate reductase chaperone AF_0160 536676e52210ffcee5cb484488586321 174 SUPERFAMILY SSF89155 3 159 1.96E-30 T 31-10-2018 IPR036411 TorD-like superfamily AF_0160 536676e52210ffcee5cb484488586321 174 Gene3D G3DSA:1.10.3480.10 1 174 2.4E-106 T 31-10-2018 AF_0670 647f57cc2647135720999b60695b92a2 360 PIRSF PIRSF001456 1 358 1.4E-154 T 31-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AF_0670 647f57cc2647135720999b60695b92a2 360 Pfam PF01264 Chorismate synthase 8 350 3.2E-146 T 31-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AF_0670 647f57cc2647135720999b60695b92a2 360 ProSitePatterns PS00789 Chorismate synthase signature 3. 324 340 - T 31-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AF_0670 647f57cc2647135720999b60695b92a2 360 ProSitePatterns PS00788 Chorismate synthase signature 2. 121 137 - T 31-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AF_0670 647f57cc2647135720999b60695b92a2 360 Gene3D G3DSA:3.60.150.10 1 359 1.0E-152 T 31-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AF_0670 647f57cc2647135720999b60695b92a2 360 TIGRFAM TIGR00033 aroC: chorismate synthase 8 352 3.0E-147 T 31-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AF_0670 647f57cc2647135720999b60695b92a2 360 SUPERFAMILY SSF103263 1 353 5.76E-143 T 31-10-2018 IPR035904 Chorismate synthase AroC superfamily KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AF_0670 647f57cc2647135720999b60695b92a2 360 Hamap MF_00300 Chorismate synthase [aroC]. 8 357 39.328 T 31-10-2018 IPR000453 Chorismate synthase GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AF_0670 647f57cc2647135720999b60695b92a2 360 ProSitePatterns PS00787 Chorismate synthase signature 1. 14 29 - T 31-10-2018 IPR020541 Chorismate synthase, conserved site GO:0004107|GO:0009073 KEGG: 00400+4.2.3.5|MetaCyc: PWY-6163 AF_0274 cacb259344a745be6e283b9ad5b0267a 354 Gene3D G3DSA:3.30.9.10 81 301 9.0E-91 T 31-10-2018 AF_0274 cacb259344a745be6e283b9ad5b0267a 354 SUPERFAMILY SSF51905 1 346 2.33E-50 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0274 cacb259344a745be6e283b9ad5b0267a 354 Pfam PF01266 FAD dependent oxidoreductase 2 340 1.7E-61 T 31-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AF_0274 cacb259344a745be6e283b9ad5b0267a 354 Gene3D G3DSA:3.50.50.60 3 344 9.0E-91 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0274 cacb259344a745be6e283b9ad5b0267a 354 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 187 202 5.2E-6 T 31-10-2018 AF_0274 cacb259344a745be6e283b9ad5b0267a 354 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 2 24 5.2E-6 T 31-10-2018 AF_1440 425390ec2122cf234af48c42a23ed2a8 613 SUPERFAMILY SSF55931 2 438 3.99E-101 T 31-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AF_1440 425390ec2122cf234af48c42a23ed2a8 613 TIGRFAM TIGR00134 gatE_arch: glutamyl-tRNA(Gln) amidotransferase, subunit E 1 611 0.0 T 31-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 AF_1440 425390ec2122cf234af48c42a23ed2a8 613 SMART SM00845 471 607 3.2E-16 T 31-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 AF_1440 425390ec2122cf234af48c42a23ed2a8 613 ProDom PD609240 SUBUNIT E AMIDOTRANSFERASE 6.3.5.- LIGASE GLUTAMYL-TRNAGLN GLU-ADT BIOSYNTHESIS TRANSFERASE B 280 398 1.0E-49 T 31-10-2018 AF_1440 425390ec2122cf234af48c42a23ed2a8 613 Pfam PF02934 GatB/GatE catalytic domain 10 437 1.4E-71 T 31-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 AF_1440 425390ec2122cf234af48c42a23ed2a8 613 SUPERFAMILY SSF89095 471 607 1.36E-12 T 31-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 AF_1440 425390ec2122cf234af48c42a23ed2a8 613 Pfam PF02637 GatB domain 472 607 1.1E-16 T 31-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 AF_1440 425390ec2122cf234af48c42a23ed2a8 613 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 176 190 - T 31-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 AF_1440 425390ec2122cf234af48c42a23ed2a8 613 Gene3D G3DSA:3.30.1360.30 273 396 1.3E-42 T 31-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 AF_1440 425390ec2122cf234af48c42a23ed2a8 613 Pfam PF02938 GAD domain 293 382 2.8E-20 T 31-10-2018 IPR029351 GAD domain Reactome: R-HSA-379726 AF_1440 425390ec2122cf234af48c42a23ed2a8 613 SUPERFAMILY SSF55261 273 396 2.29E-42 T 31-10-2018 IPR004115 GAD-like domain superfamily GO:0004812|GO:0005524|GO:0005737 Reactome: R-HSA-379726 AF_1440 425390ec2122cf234af48c42a23ed2a8 613 Hamap MF_00588 Glutamyl-tRNA(Gln) amidotransferase subunit E [gatE]. 1 613 304.373 T 31-10-2018 IPR004414 Glutamyl-tRNA(Gln) amidotransferase subunit E GO:0016884 AF_1440 425390ec2122cf234af48c42a23ed2a8 613 Gene3D G3DSA:1.10.150.380 442 532 2.8E-13 T 31-10-2018 AF_1211 f9c0db76404d06b69ece8b9a2bb4c928 685 Gene3D G3DSA:3.30.1490.20 489 565 1.3E-83 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AF_1211 f9c0db76404d06b69ece8b9a2bb4c928 685 SUPERFAMILY SSF52210 291 436 2.62E-35 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1211 f9c0db76404d06b69ece8b9a2bb4c928 685 Gene3D G3DSA:3.30.470.20 474 678 1.3E-83 T 31-10-2018 AF_1211 f9c0db76404d06b69ece8b9a2bb4c928 685 SUPERFAMILY SSF56059 479 683 3.71E-46 T 31-10-2018 AF_1211 f9c0db76404d06b69ece8b9a2bb4c928 685 SUPERFAMILY SSF52210 126 290 3.27E-48 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1211 f9c0db76404d06b69ece8b9a2bb4c928 685 Pfam PF13380 CoA binding domain 8 132 7.2E-27 T 31-10-2018 IPR003781 CoA-binding GO:0048037 AF_1211 f9c0db76404d06b69ece8b9a2bb4c928 685 TIGRFAM TIGR02717 AcCoA-syn-alpha: acetyl coenzyme A synthetase (ADP forming), alpha domain 1 435 1.5E-191 T 31-10-2018 IPR014089 Acetate-CoA ligase [ADP-forming], alpha domain KEGG: 00010+6.2.1.13|KEGG: 00620+6.2.1.13|KEGG: 00640+6.2.1.13|MetaCyc: PWY-5483|MetaCyc: PWY-5535 AF_1211 f9c0db76404d06b69ece8b9a2bb4c928 685 Gene3D G3DSA:3.40.50.720 1 126 1.9E-45 T 31-10-2018 AF_1211 f9c0db76404d06b69ece8b9a2bb4c928 685 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 148 284 1.1E-58 T 31-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain AF_1211 f9c0db76404d06b69ece8b9a2bb4c928 685 Gene3D G3DSA:3.40.50.261 127 288 4.9E-66 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1211 f9c0db76404d06b69ece8b9a2bb4c928 685 Pfam PF13549 ATP-grasp domain 473 681 2.6E-77 T 31-10-2018 AF_1211 f9c0db76404d06b69ece8b9a2bb4c928 685 SUPERFAMILY SSF51735 2 127 2.16E-40 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1211 f9c0db76404d06b69ece8b9a2bb4c928 685 Gene3D G3DSA:3.40.50.261 289 445 3.5E-43 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1211 f9c0db76404d06b69ece8b9a2bb4c928 685 SMART SM00881 4 97 2.7E-40 T 31-10-2018 IPR003781 CoA-binding GO:0048037 AF_0175 961373dcf135c2b7fb45c2145fd80c87 251 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 97 108 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0175 961373dcf135c2b7fb45c2145fd80c87 251 Pfam PF13247 4Fe-4S dicluster domain 163 197 3.5E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0175 961373dcf135c2b7fb45c2145fd80c87 251 Pfam PF13247 4Fe-4S dicluster domain 59 119 1.0E-15 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0175 961373dcf135c2b7fb45c2145fd80c87 251 Gene3D G3DSA:3.30.70.20 1 45 6.3E-10 T 31-10-2018 AF_0175 961373dcf135c2b7fb45c2145fd80c87 251 Pfam PF12800 4Fe-4S binding domain 11 24 0.0029 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0175 961373dcf135c2b7fb45c2145fd80c87 251 SUPERFAMILY SSF54862 1 233 9.63E-71 T 31-10-2018 AF_0133 03fd64a99b74dfb5098de8314ff33c27 411 Gene3D G3DSA:3.40.47.10 1 408 2.6E-87 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0133 03fd64a99b74dfb5098de8314ff33c27 411 SUPERFAMILY SSF53901 243 406 3.87E-16 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0133 03fd64a99b74dfb5098de8314ff33c27 411 PIRSF PIRSF000429 1 403 1.8E-27 T 31-10-2018 IPR002155 Thiolase GO:0016747 AF_0133 03fd64a99b74dfb5098de8314ff33c27 411 SUPERFAMILY SSF53901 4 244 7.2E-27 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0133 03fd64a99b74dfb5098de8314ff33c27 411 Pfam PF00108 Thiolase, N-terminal domain 11 195 1.9E-8 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AF_1929 b25cc0aaf32fafce4ba1ba9f9533db63 421 Gene3D G3DSA:3.40.50.740 53 105 3.1E-19 T 31-10-2018 AF_1929 b25cc0aaf32fafce4ba1ba9f9533db63 421 SUPERFAMILY SSF53706 4 419 8.9E-68 T 31-10-2018 AF_1929 b25cc0aaf32fafce4ba1ba9f9533db63 421 Gene3D G3DSA:3.40.228.10 217 287 1.9E-11 T 31-10-2018 AF_1929 b25cc0aaf32fafce4ba1ba9f9533db63 421 Gene3D G3DSA:3.40.50.740 288 413 1.9E-11 T 31-10-2018 AF_1929 b25cc0aaf32fafce4ba1ba9f9533db63 421 Pfam PF00384 Molybdopterin oxidoreductase 44 402 2.7E-11 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1929 b25cc0aaf32fafce4ba1ba9f9533db63 421 TIGRFAM TIGR03129 one_C_dehyd_B: formylmethanofuran dehydrogenase subunit B 6 416 4.2E-180 T 31-10-2018 IPR016457 Formylmethanofuran dehydrogenase, subunit B GO:0015948|GO:0018493 KEGG: 00680+1.2.7.12|MetaCyc: PWY-5209|MetaCyc: PWY-7784 AF_1929 b25cc0aaf32fafce4ba1ba9f9533db63 421 Gene3D G3DSA:3.40.228.10 106 205 3.1E-19 T 31-10-2018 AF_1929 b25cc0aaf32fafce4ba1ba9f9533db63 421 PIRSF PIRSF005646 1 421 1.6E-191 T 31-10-2018 IPR016457 Formylmethanofuran dehydrogenase, subunit B GO:0015948|GO:0018493 KEGG: 00680+1.2.7.12|MetaCyc: PWY-5209|MetaCyc: PWY-7784 AF_0497 ad198b84e3f82922f9e89c00adf3d915 781 Gene3D G3DSA:1.10.132.60 606 781 1.0E-47 T 31-10-2018 AF_0497 ad198b84e3f82922f9e89c00adf3d915 781 Pfam PF03104 DNA polymerase family B, exonuclease domain 197 291 1.3E-16 T 31-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AF_0497 ad198b84e3f82922f9e89c00adf3d915 781 Pfam PF03104 DNA polymerase family B, exonuclease domain 29 194 3.0E-15 T 31-10-2018 IPR006133 DNA-directed DNA polymerase, family B, exonuclease domain KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AF_0497 ad198b84e3f82922f9e89c00adf3d915 781 Gene3D G3DSA:3.30.420.10 136 360 2.1E-114 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AF_0497 ad198b84e3f82922f9e89c00adf3d915 781 SMART SM00486 160 555 7.6E-128 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AF_0497 ad198b84e3f82922f9e89c00adf3d915 781 TIGRFAM TIGR00592 pol2: DNA polymerase (pol2) 390 759 2.2E-84 T 31-10-2018 AF_0497 ad198b84e3f82922f9e89c00adf3d915 781 SUPERFAMILY SSF56672 361 771 3.23E-115 T 31-10-2018 AF_0497 ad198b84e3f82922f9e89c00adf3d915 781 Gene3D G3DSA:3.30.342.10 9 377 2.1E-114 T 31-10-2018 AF_0497 ad198b84e3f82922f9e89c00adf3d915 781 Gene3D G3DSA:3.90.1600.10 391 594 8.1E-65 T 31-10-2018 IPR023211 DNA polymerase, palm domain superfamily KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AF_0497 ad198b84e3f82922f9e89c00adf3d915 781 Gene3D G3DSA:1.10.287.690 452 505 8.1E-65 T 31-10-2018 AF_0497 ad198b84e3f82922f9e89c00adf3d915 781 SUPERFAMILY SSF53098 5 382 2.12E-75 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily AF_0497 ad198b84e3f82922f9e89c00adf3d915 781 Pfam PF00136 DNA polymerase family B 348 759 1.6E-74 T 31-10-2018 IPR006134 DNA-directed DNA polymerase, family B, multifunctional domain GO:0000166|GO:0003677 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AF_0497 ad198b84e3f82922f9e89c00adf3d915 781 ProSitePatterns PS00116 DNA polymerase family B signature. 543 551 - T 31-10-2018 IPR017964 DNA-directed DNA polymerase, family B, conserved site GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AF_0497 ad198b84e3f82922f9e89c00adf3d915 781 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 489 501 2.2E-10 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AF_0497 ad198b84e3f82922f9e89c00adf3d915 781 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 541 549 2.2E-10 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AF_0497 ad198b84e3f82922f9e89c00adf3d915 781 PRINTS PR00106 DNA-directed DNA-polymerase family B signature 407 420 2.2E-10 T 31-10-2018 IPR006172 DNA-directed DNA polymerase, family B GO:0000166|GO:0003676|GO:0003887 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AF_2238 d53f4eb75cf6b96fb596c8db103c5688 545 Gene3D G3DSA:3.50.7.10 218 369 7.6E-212 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily AF_2238 d53f4eb75cf6b96fb596c8db103c5688 545 Pfam PF00118 TCP-1/cpn60 chaperonin family 35 525 1.3E-189 T 31-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 AF_2238 d53f4eb75cf6b96fb596c8db103c5688 545 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 89 97 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AF_2238 d53f4eb75cf6b96fb596c8db103c5688 545 SUPERFAMILY SSF52029 212 378 8.63E-62 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily AF_2238 d53f4eb75cf6b96fb596c8db103c5688 545 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AF_2238 d53f4eb75cf6b96fb596c8db103c5688 545 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 8 525 4.6E-261 T 31-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 AF_2238 d53f4eb75cf6b96fb596c8db103c5688 545 Gene3D G3DSA:1.10.560.10 28 522 7.6E-212 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily AF_2238 d53f4eb75cf6b96fb596c8db103c5688 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 407 419 1.8E-37 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AF_2238 d53f4eb75cf6b96fb596c8db103c5688 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 89 108 1.8E-37 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AF_2238 d53f4eb75cf6b96fb596c8db103c5688 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 59 77 1.8E-37 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AF_2238 d53f4eb75cf6b96fb596c8db103c5688 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 1.8E-37 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AF_2238 d53f4eb75cf6b96fb596c8db103c5688 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 373 395 1.8E-37 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AF_2238 d53f4eb75cf6b96fb596c8db103c5688 545 SUPERFAMILY SSF48592 17 524 4.32E-97 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily AF_2238 d53f4eb75cf6b96fb596c8db103c5688 545 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 61 77 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AF_2238 d53f4eb75cf6b96fb596c8db103c5688 545 Gene3D G3DSA:3.30.260.10 147 405 7.6E-212 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily AF_2238 d53f4eb75cf6b96fb596c8db103c5688 545 SUPERFAMILY SSF54849 147 404 2.75E-29 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily AF_2053 c973ad3dc713781a5141a2513929d11f 366 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 26 240 6.3E-73 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 AF_2053 c973ad3dc713781a5141a2513929d11f 366 Gene3D G3DSA:3.40.50.970 12 246 1.1E-80 T 31-10-2018 AF_2053 c973ad3dc713781a5141a2513929d11f 366 SUPERFAMILY SSF52922 244 360 7.85E-23 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AF_2053 c973ad3dc713781a5141a2513929d11f 366 Gene3D G3DSA:3.40.50.920 247 365 2.5E-21 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AF_2053 c973ad3dc713781a5141a2513929d11f 366 Pfam PF17147 Pyruvate:ferredoxin oxidoreductase core domain II 254 347 1.5E-25 T 31-10-2018 IPR033412 Pyruvate:ferredoxin oxidoreductase, core domain II AF_2053 c973ad3dc713781a5141a2513929d11f 366 SUPERFAMILY SSF52518 14 214 4.51E-60 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold AF_0447 464f02e9658fa2baff3b419c0c5298de 182 Gene3D G3DSA:2.60.40.10 32 161 3.5E-42 T 31-10-2018 IPR013783 Immunoglobulin-like fold AF_0447 464f02e9658fa2baff3b419c0c5298de 182 SMART SM00769 33 150 4.4E-32 T 31-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 AF_0447 464f02e9658fa2baff3b419c0c5298de 182 Pfam PF03168 Late embryogenesis abundant protein 53 146 9.6E-16 T 31-10-2018 IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup AF_0447 464f02e9658fa2baff3b419c0c5298de 182 SUPERFAMILY SSF117070 13 151 1.57E-18 T 31-10-2018 AF_0537 faf2ac3fc1c5cfbf49d4442685688933 150 Pfam PF00467 KOW motif 93 124 5.0E-8 T 31-10-2018 IPR005824 KOW AF_0537 faf2ac3fc1c5cfbf49d4442685688933 150 Gene3D G3DSA:2.30.30.30 90 149 2.3E-26 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 AF_0537 faf2ac3fc1c5cfbf49d4442685688933 150 Gene3D G3DSA:3.30.70.940 3 89 3.1E-32 T 31-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AF_0537 faf2ac3fc1c5cfbf49d4442685688933 150 SUPERFAMILY SSF82679 3 75 7.06E-5 T 31-10-2018 IPR036735 NusG, N-terminal domain superfamily GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AF_0537 faf2ac3fc1c5cfbf49d4442685688933 150 SMART SM00738 1 85 2.2E-26 T 31-10-2018 IPR006645 NusG, N-terminal GO:0006355 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AF_0537 faf2ac3fc1c5cfbf49d4442685688933 150 ProSitePatterns PS01108 Ribosomal protein L24 signature. 94 111 - T 31-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_0537 faf2ac3fc1c5cfbf49d4442685688933 150 SUPERFAMILY SSF50104 58 147 1.89E-18 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily AF_0537 faf2ac3fc1c5cfbf49d4442685688933 150 Hamap MF_00950 Transcription elongation factor Spt5 [spt5]. 3 146 40.025 T 31-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 AF_0537 faf2ac3fc1c5cfbf49d4442685688933 150 Pfam PF03439 Early transcription elongation factor of RNA pol II, NGN section 3 82 2.9E-25 T 31-10-2018 IPR005100 NGN domain Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-75955|Reactome: R-HSA-77075 AF_0537 faf2ac3fc1c5cfbf49d4442685688933 150 SMART SM00739 90 117 2.0E-6 T 31-10-2018 IPR005824 KOW AF_0537 faf2ac3fc1c5cfbf49d4442685688933 150 TIGRFAM TIGR00405 KOW_elon_Spt5: transcription elongation factor Spt5 5 149 1.9E-76 T 31-10-2018 IPR011590 Transcription elongation factor Spt5, archaeal GO:0003746 AF_1488 ea65465c83e062cffcc43a401e9b7d5c 174 Hamap MF_00243 Nicotinamide-nucleotide adenylyltransferase. 1 174 73.121 T 31-10-2018 IPR006418 Nicotinamide-nucleotide adenylyltransferase, archaeal type GO:0000309|GO:0005737|GO:0009435 KEGG: 00760+2.7.7.1 AF_1488 ea65465c83e062cffcc43a401e9b7d5c 174 SUPERFAMILY SSF52374 6 167 1.66E-29 T 31-10-2018 AF_1488 ea65465c83e062cffcc43a401e9b7d5c 174 Pfam PF01467 Cytidylyltransferase-like 9 138 5.5E-16 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AF_1488 ea65465c83e062cffcc43a401e9b7d5c 174 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 6 67 3.3E-17 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AF_1488 ea65465c83e062cffcc43a401e9b7d5c 174 Gene3D G3DSA:3.40.50.620 5 174 5.3E-40 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_1042 cb9ca0ac4353c940c2b86bbc22222468 121 SUPERFAMILY SSF52172 1 118 7.83E-38 T 31-10-2018 IPR011006 CheY-like superfamily AF_1042 cb9ca0ac4353c940c2b86bbc22222468 121 SMART SM00448 2 114 8.1E-37 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_1042 cb9ca0ac4353c940c2b86bbc22222468 121 Pfam PF00072 Response regulator receiver domain 4 114 1.1E-32 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_1042 cb9ca0ac4353c940c2b86bbc22222468 121 Gene3D G3DSA:3.40.50.12740 3 121 4.2E-38 T 31-10-2018 AF_0463 cdca774e90139ddced6e2d2131963a54 200 Gene3D G3DSA:3.30.70.20 59 130 2.3E-11 T 31-10-2018 AF_0463 cdca774e90139ddced6e2d2131963a54 200 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 142 153 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0463 cdca774e90139ddced6e2d2131963a54 200 SUPERFAMILY SSF54862 136 197 4.81E-12 T 31-10-2018 AF_0463 cdca774e90139ddced6e2d2131963a54 200 Gene3D G3DSA:3.30.70.3270 3 58 1.5E-6 T 31-10-2018 AF_0463 cdca774e90139ddced6e2d2131963a54 200 Pfam PF13237 4Fe-4S dicluster domain 140 187 7.4E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0463 cdca774e90139ddced6e2d2131963a54 200 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 176 187 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0463 cdca774e90139ddced6e2d2131963a54 200 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 32 43 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0463 cdca774e90139ddced6e2d2131963a54 200 Gene3D G3DSA:3.30.70.20 131 200 1.5E-11 T 31-10-2018 AF_0463 cdca774e90139ddced6e2d2131963a54 200 Pfam PF12800 4Fe-4S binding domain 61 77 0.044 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0463 cdca774e90139ddced6e2d2131963a54 200 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 96 107 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0463 cdca774e90139ddced6e2d2131963a54 200 SUPERFAMILY SSF54862 24 156 7.09E-25 T 31-10-2018 AF_0463 cdca774e90139ddced6e2d2131963a54 200 Pfam PF00037 4Fe-4S binding domain 90 112 6.9E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0463 cdca774e90139ddced6e2d2131963a54 200 Pfam PF00037 4Fe-4S binding domain 25 48 1.9E-6 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1885 f49ad33a8c7596e134ec0015502bb6a6 76 ProSitePatterns PS01110 RNA polymerases H / 23 Kd subunits signature. 8 21 - T 31-10-2018 IPR020608 RNA polymerase, subunit H/Rpb5, conserved site Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AF_1885 f49ad33a8c7596e134ec0015502bb6a6 76 Hamap MF_00025 DNA-directed RNA polymerase subunit H [rpoH]. 3 76 24.313 T 31-10-2018 IPR020609 Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AF_1885 f49ad33a8c7596e134ec0015502bb6a6 76 SUPERFAMILY SSF55287 2 76 2.22E-27 T 31-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AF_1885 f49ad33a8c7596e134ec0015502bb6a6 76 Gene3D G3DSA:3.90.940.20 1 76 8.3E-33 T 31-10-2018 IPR035913 RPB5-like RNA polymerase subunit superfamily Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AF_1885 f49ad33a8c7596e134ec0015502bb6a6 76 ProDom PD005155 RNA POLYMERASE DNA-DIRECTED SUBUNIT NUCLEOTIDYLTRANSFERASE TRANSFERASE TRANSCRIPTION II H POLYPEPTIDE 10 75 5.0E-30 T 31-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AF_1885 f49ad33a8c7596e134ec0015502bb6a6 76 Pfam PF01191 RNA polymerase Rpb5, C-terminal domain 4 75 4.9E-32 T 31-10-2018 IPR000783 RNA polymerase, subunit H/Rpb5 C-terminal GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AF_1851 d1d605e66a020732c7fdcbd53c0ecb6c 334 Pfam PF02754 Cysteine-rich domain 222 307 4.8E-11 T 31-10-2018 IPR004017 Cysteine-rich domain AF_1851 d1d605e66a020732c7fdcbd53c0ecb6c 334 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1851 d1d605e66a020732c7fdcbd53c0ecb6c 334 SUPERFAMILY SSF54862 5 70 6.45E-5 T 31-10-2018 AF_1781 94591738212dcd7746003c6afcd8528c 444 SUPERFAMILY SSF52096 26 192 1.58E-26 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AF_1781 94591738212dcd7746003c6afcd8528c 444 Pfam PF01957 NfeD-like C-terminal, partner-binding 290 427 2.0E-34 T 31-10-2018 IPR002810 NfeD-like, C-terminal domain AF_1781 94591738212dcd7746003c6afcd8528c 444 Gene3D G3DSA:2.40.50.140 361 435 5.6E-16 T 31-10-2018 AF_1781 94591738212dcd7746003c6afcd8528c 444 Pfam PF00574 Clp protease 63 192 1.2E-4 T 31-10-2018 IPR023562 Clp protease proteolytic subunit /Translocation-enhancing protein TepA AF_1781 94591738212dcd7746003c6afcd8528c 444 Gene3D G3DSA:3.90.226.10 25 240 8.4E-47 T 31-10-2018 AF_1781 94591738212dcd7746003c6afcd8528c 444 SUPERFAMILY SSF141322 366 429 1.57E-17 T 31-10-2018 AF_1516 a5436b7141009a12e3671593c4497744 219 Pfam PF03749 Sugar fermentation stimulation protein 15 200 3.2E-42 T 31-10-2018 IPR005224 Sugar fermentation stimulation protein AF_1516 a5436b7141009a12e3671593c4497744 219 TIGRFAM TIGR00230 sfsA: sugar fermentation stimulation protein 1 219 2.5E-89 T 31-10-2018 IPR005224 Sugar fermentation stimulation protein AF_1516 a5436b7141009a12e3671593c4497744 219 Gene3D G3DSA:3.40.1350.60 79 217 4.6E-24 T 31-10-2018 AF_1516 a5436b7141009a12e3671593c4497744 219 Hamap MF_00095 Sugar fermentation stimulation protein A [sfsA]. 3 218 37.37 T 31-10-2018 IPR005224 Sugar fermentation stimulation protein AF_1516 a5436b7141009a12e3671593c4497744 219 Gene3D G3DSA:2.40.50.580 1 78 4.3E-30 T 31-10-2018 AF_1946 c04786895659dfa7cbb22a8ee49d39a5 1088 Gene3D G3DSA:3.90.70.10 585 815 1.0E-48 T 31-10-2018 AF_1946 c04786895659dfa7cbb22a8ee49d39a5 1088 ProSitePatterns PS00139 Eukaryotic thiol (cysteine) proteases cysteine active site. 612 623 - T 31-10-2018 IPR000169 Cysteine peptidase, cysteine active site AF_1946 c04786895659dfa7cbb22a8ee49d39a5 1088 SMART SM00645 594 815 4.9E-30 T 31-10-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 AF_1946 c04786895659dfa7cbb22a8ee49d39a5 1088 TIGRFAM TIGR01451 B_ant_repeat: conserved repeat domain 47 72 5.4E-4 T 31-10-2018 IPR001434 Domain of unknown function DUF11 AF_1946 c04786895659dfa7cbb22a8ee49d39a5 1088 SUPERFAMILY SSF54001 586 819 4.56E-45 T 31-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AF_1946 c04786895659dfa7cbb22a8ee49d39a5 1088 Gene3D G3DSA:2.60.40.10 233 346 3.4E-17 T 31-10-2018 IPR013783 Immunoglobulin-like fold AF_1946 c04786895659dfa7cbb22a8ee49d39a5 1088 Gene3D G3DSA:2.60.40.10 453 564 7.9E-16 T 31-10-2018 IPR013783 Immunoglobulin-like fold AF_1946 c04786895659dfa7cbb22a8ee49d39a5 1088 SUPERFAMILY SSF69318 820 1075 4.05E-31 T 31-10-2018 AF_1946 c04786895659dfa7cbb22a8ee49d39a5 1088 Pfam PF00112 Papain family cysteine protease 594 813 3.4E-37 T 31-10-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 AF_1946 c04786895659dfa7cbb22a8ee49d39a5 1088 Gene3D G3DSA:2.60.40.10 350 452 2.2E-10 T 31-10-2018 IPR013783 Immunoglobulin-like fold AF_1946 c04786895659dfa7cbb22a8ee49d39a5 1088 Pfam PF07705 CARDB 459 556 7.0E-20 T 31-10-2018 IPR011635 CARDB domain AF_1946 c04786895659dfa7cbb22a8ee49d39a5 1088 Pfam PF07705 CARDB 350 447 8.0E-16 T 31-10-2018 IPR011635 CARDB domain AF_1946 c04786895659dfa7cbb22a8ee49d39a5 1088 Pfam PF07705 CARDB 235 338 3.4E-21 T 31-10-2018 IPR011635 CARDB domain AF_1946 c04786895659dfa7cbb22a8ee49d39a5 1088 PRINTS PR00705 Papain cysteine protease (C1) family signature 771 777 2.7E-5 T 31-10-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 AF_1946 c04786895659dfa7cbb22a8ee49d39a5 1088 PRINTS PR00705 Papain cysteine protease (C1) family signature 748 758 2.7E-5 T 31-10-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 AF_1946 c04786895659dfa7cbb22a8ee49d39a5 1088 PRINTS PR00705 Papain cysteine protease (C1) family signature 612 627 2.7E-5 T 31-10-2018 IPR000668 Peptidase C1A, papain C-terminal GO:0006508|GO:0008234 AF_2139 8657ca3ed864de16bd00f4dea2c82eef 182 Gene3D G3DSA:3.30.420.470 2 172 5.0E-23 T 31-10-2018 AF_2139 8657ca3ed864de16bd00f4dea2c82eef 182 Pfam PF13358 DDE superfamily endonuclease 12 148 4.7E-28 T 31-10-2018 IPR038717 Tc1-like transposase, DDE domain AF_2139 8657ca3ed864de16bd00f4dea2c82eef 182 SUPERFAMILY SSF53098 56 149 5.5E-7 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily AF_1352 8657ca3ed864de16bd00f4dea2c82eef 182 Gene3D G3DSA:3.30.420.470 2 172 5.0E-23 T 31-10-2018 AF_1352 8657ca3ed864de16bd00f4dea2c82eef 182 Pfam PF13358 DDE superfamily endonuclease 12 148 4.7E-28 T 31-10-2018 IPR038717 Tc1-like transposase, DDE domain AF_1352 8657ca3ed864de16bd00f4dea2c82eef 182 SUPERFAMILY SSF53098 56 149 5.5E-7 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily AF_1941 0e9dbc0a4144670e8922169aa1ff79a5 80 SUPERFAMILY SSF82697 3 76 2.44E-24 T 31-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AF_1941 0e9dbc0a4144670e8922169aa1ff79a5 80 Hamap MF_01926 Phosphoribosylformylglycinamidine synthase subunit PurS [purS]. 1 78 20.177 T 31-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AF_1941 0e9dbc0a4144670e8922169aa1ff79a5 80 Gene3D G3DSA:3.30.1280.10 1 80 9.1E-29 T 31-10-2018 IPR036604 Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AF_1941 0e9dbc0a4144670e8922169aa1ff79a5 80 Pfam PF02700 Phosphoribosylformylglycinamidine (FGAM) synthase 3 77 4.2E-29 T 31-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AF_1941 0e9dbc0a4144670e8922169aa1ff79a5 80 ProDom PD010362 PHOSPHORIBOSYLFORMYLGLYCINAMIDINE PURS SYNTHETASE SYNTHASE COMPONENT SYNTHASE LIGASE FGAM UPF0062 I 9 76 8.0E-20 T 31-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AF_1941 0e9dbc0a4144670e8922169aa1ff79a5 80 TIGRFAM TIGR00302 TIGR00302: phosphoribosylformylglycinamidine synthase, purS protein 1 80 1.3E-37 T 31-10-2018 IPR003850 Phosphoribosylformylglycinamidine synthase subunit PurS KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AF_1638 b5a84527f8dc5b81d21c90f4487cdfb5 441 Gene3D G3DSA:3.30.70.150 3 133 1.1E-42 T 31-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AF_1638 b5a84527f8dc5b81d21c90f4487cdfb5 441 Pfam PF02788 Ribulose bisphosphate carboxylase large chain, N-terminal domain 9 129 3.9E-47 T 31-10-2018 IPR017443 Ribulose bisphosphate carboxylase, large subunit, ferrodoxin-like N-terminal GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AF_1638 b5a84527f8dc5b81d21c90f4487cdfb5 441 Hamap MF_01133 Ribulose bisphosphate carboxylase [rbcL]. 8 436 52.679 T 31-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AF_1638 b5a84527f8dc5b81d21c90f4487cdfb5 441 TIGRFAM TIGR03326 rubisco_III: ribulose bisphosphate carboxylase, type III 9 435 5.3E-229 T 31-10-2018 IPR017712 Ribulose bisphosphate carboxylase, type III GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AF_1638 b5a84527f8dc5b81d21c90f4487cdfb5 441 SUPERFAMILY SSF54966 7 134 4.45E-40 T 31-10-2018 IPR036422 RuBisCO large subunit, N-terminal domain superfamily GO:0015977|GO:0016984 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AF_1638 b5a84527f8dc5b81d21c90f4487cdfb5 441 Gene3D G3DSA:3.20.20.110 134 435 2.6E-120 T 31-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AF_1638 b5a84527f8dc5b81d21c90f4487cdfb5 441 SUPERFAMILY SSF51649 133 438 1.83E-106 T 31-10-2018 IPR036376 Ribulose bisphosphate carboxylase, large subunit, C-terminal domain superfamily GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AF_1638 b5a84527f8dc5b81d21c90f4487cdfb5 441 Pfam PF00016 Ribulose bisphosphate carboxylase large chain, catalytic domain 143 435 6.6E-97 T 31-10-2018 IPR000685 Ribulose bisphosphate carboxylase, large subunit, C-terminal GO:0000287 KEGG: 00630+4.1.1.39|KEGG: 00710+4.1.1.39|MetaCyc: PWY-5532|MetaCyc: PWY-5723 AF_0507 16e3873972dd22388eb960818139869b 342 SUPERFAMILY SSF55103 201 326 2.13E-6 T 31-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AF_0507 16e3873972dd22388eb960818139869b 342 Gene3D G3DSA:3.30.465.40 1 165 1.3E-31 T 31-10-2018 AF_0507 16e3873972dd22388eb960818139869b 342 Pfam PF01565 FAD binding domain 1 112 1.6E-25 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AF_0507 16e3873972dd22388eb960818139869b 342 SUPERFAMILY SSF56176 1 145 7.94E-29 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AF_0296 03c6aa621c6d2420bfbc3179c3360f20 157 SUPERFAMILY SSF88723 3 118 2.55E-7 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_0296 03c6aa621c6d2420bfbc3179c3360f20 157 TIGRFAM TIGR00305 TIGR00305: putative toxin-antitoxin system toxin component, PIN family 3 116 8.0E-48 T 31-10-2018 IPR002850 PIN family, putative toxin-antitoxin system toxin component AF_0296 03c6aa621c6d2420bfbc3179c3360f20 157 SMART SM00670 2 115 7.1E-15 T 31-10-2018 IPR002716 PIN domain AF_0296 03c6aa621c6d2420bfbc3179c3360f20 157 Pfam PF13470 PIN domain 3 111 2.9E-17 T 31-10-2018 IPR002716 PIN domain AF_0024 ec78f28e0cfc52a06be5e8222f240c5b 416 SUPERFAMILY SSF56796 32 414 3.01E-102 T 31-10-2018 AF_0024 ec78f28e0cfc52a06be5e8222f240c5b 416 Pfam PF00465 Iron-containing alcohol dehydrogenase 37 403 1.3E-100 T 31-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 AF_0024 ec78f28e0cfc52a06be5e8222f240c5b 416 Gene3D G3DSA:3.40.50.1970 30 212 5.2E-47 T 31-10-2018 AF_0024 ec78f28e0cfc52a06be5e8222f240c5b 416 Gene3D G3DSA:1.20.1090.10 214 415 8.6E-59 T 31-10-2018 AF_0024 ec78f28e0cfc52a06be5e8222f240c5b 416 ProSitePatterns PS00060 Iron-containing alcohol dehydrogenases signature 2. 288 308 - T 31-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 AF_0627 c88aa1437affc12c8157ea5d9cbe3738 340 SUPERFAMILY SSF54862 237 330 2.42E-17 T 31-10-2018 AF_0627 c88aa1437affc12c8157ea5d9cbe3738 340 Gene3D G3DSA:3.30.70.20 265 302 1.1E-7 T 31-10-2018 AF_0627 c88aa1437affc12c8157ea5d9cbe3738 340 Pfam PF00037 4Fe-4S binding domain 306 328 5.7E-5 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0627 c88aa1437affc12c8157ea5d9cbe3738 340 Pfam PF00037 4Fe-4S binding domain 278 300 2.1E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0627 c88aa1437affc12c8157ea5d9cbe3738 340 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 284 295 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0627 c88aa1437affc12c8157ea5d9cbe3738 340 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 312 323 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0627 c88aa1437affc12c8157ea5d9cbe3738 340 Gene3D G3DSA:3.30.70.20 303 337 2.2E-5 T 31-10-2018 AF_1983 5df09ca3848fe8670e314e849bc88c70 322 Gene3D G3DSA:3.40.50.1980 29 178 1.2E-26 T 31-10-2018 AF_1983 5df09ca3848fe8670e314e849bc88c70 322 Pfam PF01297 Zinc-uptake complex component A periplasmic 33 285 6.0E-31 T 31-10-2018 IPR006127 Periplasmic solute binding protein, ZnuA-like GO:0030001|GO:0046872 AF_1983 5df09ca3848fe8670e314e849bc88c70 322 SUPERFAMILY SSF53807 23 286 2.21E-44 T 31-10-2018 AF_2094 f239766a42aede201616e3863a2e2b40 90 Gene3D G3DSA:2.30.30.580 1 90 2.8E-48 T 31-10-2018 AF_1893 a7abe2b50f3ea3925ba3c13b88855948 194 TIGRFAM TIGR01028 uS7_euk_arch: ribosomal protein uS7 9 194 2.8E-96 T 31-10-2018 IPR005716 Ribosomal protein S5/S7, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1893 a7abe2b50f3ea3925ba3c13b88855948 194 Pfam PF00177 Ribosomal protein S7p/S5e 50 194 1.9E-41 T 31-10-2018 IPR023798 Ribosomal protein S7 domain AF_1893 a7abe2b50f3ea3925ba3c13b88855948 194 Hamap MF_00480_A 30S ribosomal protein S7 [rpsG]. 10 194 41.036 T 31-10-2018 IPR026018 Ribosomal protein S7, archaeal AF_1893 a7abe2b50f3ea3925ba3c13b88855948 194 ProSitePatterns PS00052 Ribosomal protein S7 signature. 60 86 - T 31-10-2018 IPR020606 Ribosomal protein S7, conserved site GO:0003723|GO:0003735|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1893 a7abe2b50f3ea3925ba3c13b88855948 194 PIRSF PIRSF002122 2 194 1.6E-47 T 31-10-2018 IPR000235 Ribosomal protein S5/S7 GO:0006412 AF_1893 a7abe2b50f3ea3925ba3c13b88855948 194 SUPERFAMILY SSF47973 12 194 2.62E-63 T 31-10-2018 IPR036823 Ribosomal protein S7 domain superfamily AF_1893 a7abe2b50f3ea3925ba3c13b88855948 194 Gene3D G3DSA:1.10.455.10 2 194 1.1E-81 T 31-10-2018 IPR036823 Ribosomal protein S7 domain superfamily AF_0072 569ca95b521bb804382fa3660359cd12 241 Pfam PF01881 CRISPR associated protein Cas6 96 240 9.5E-39 T 31-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 AF_0072 569ca95b521bb804382fa3660359cd12 241 Gene3D G3DSA:3.30.70.1900 124 241 4.7E-38 T 31-10-2018 AF_0072 569ca95b521bb804382fa3660359cd12 241 Gene3D G3DSA:3.30.70.1890 1 123 1.1E-31 T 31-10-2018 AF_0072 569ca95b521bb804382fa3660359cd12 241 PIRSF PIRSF005054 1 241 4.7E-68 T 31-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 AF_0072 569ca95b521bb804382fa3660359cd12 241 TIGRFAM TIGR01877 cas_cas6: CRISPR-associated endoribonuclease Cas6 42 239 6.5E-53 T 31-10-2018 IPR010156 CRISPR-associated protein, Cas6 GO:0016788 AF_0811 6c4f27de651e86d5cd4e5cb3885be4fc 364 SUPERFAMILY SSF46548 281 362 3.01E-14 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_0811 6c4f27de651e86d5cd4e5cb3885be4fc 364 TIGRFAM TIGR00273 TIGR00273: iron-sulfur cluster-binding protein 12 358 3.7E-163 T 31-10-2018 IPR004452 4Fe-4S binding protein GO:0019516 AF_0811 6c4f27de651e86d5cd4e5cb3885be4fc 364 Pfam PF13183 4Fe-4S dicluster domain 284 347 3.3E-10 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0811 6c4f27de651e86d5cd4e5cb3885be4fc 364 SUPERFAMILY SSF100950 54 256 2.18E-24 T 31-10-2018 IPR037171 NagB/RpiA transferase-like AF_0811 6c4f27de651e86d5cd4e5cb3885be4fc 364 Gene3D G3DSA:3.40.50.10420 109 245 3.7E-7 T 31-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily AF_0811 6c4f27de651e86d5cd4e5cb3885be4fc 364 Pfam PF02589 LUD domain 59 237 4.6E-34 T 31-10-2018 IPR003741 LUD domain AF_0811 6c4f27de651e86d5cd4e5cb3885be4fc 364 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 286 297 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1147 5f67b3f2fafda81b3eb26e5806360972 379 SUPERFAMILY SSF56266 11 376 8.37E-118 T 31-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AF_1147 5f67b3f2fafda81b3eb26e5806360972 379 Gene3D G3DSA:3.60.70.12 5 248 9.0E-81 T 31-10-2018 IPR016117 ArgJ-like domain superfamily KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AF_1147 5f67b3f2fafda81b3eb26e5806360972 379 TIGRFAM TIGR00120 ArgJ: glutamate N-acetyltransferase/amino-acid acetyltransferase 1 379 3.5E-170 T 31-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AF_1147 5f67b3f2fafda81b3eb26e5806360972 379 Hamap MF_01106 Arginine biosynthesis bifunctional protein ArgJ [argJ]. 1 379 115.487 T 31-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AF_1147 5f67b3f2fafda81b3eb26e5806360972 379 Gene3D G3DSA:3.10.20.340 249 379 1.0E-40 T 31-10-2018 AF_1147 5f67b3f2fafda81b3eb26e5806360972 379 Pfam PF01960 ArgJ family 11 379 3.0E-128 T 31-10-2018 IPR002813 Arginine biosynthesis protein ArgJ GO:0004358|GO:0006526 KEGG: 00220+2.3.1.35+2.3.1.1|MetaCyc: PWY-5154 AF_1147 5f67b3f2fafda81b3eb26e5806360972 379 ProDom PD004193 ACETYLTRANSFERASE ORNITHINE ARGININE BIOSYNTHESIS ARGJ GLUTAMATE N-ACETYLTRANSFERASE TRANSFERASE ACYLTRANSFERASE BIFUNCTIONAL 30 379 0.0 T 31-10-2018 AF_1665 cc60e348a1ea3da3523bfcecf89fff29 322 PIRSF PIRSF001439 1 320 8.0E-91 T 31-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 AF_1665 cc60e348a1ea3da3523bfcecf89fff29 322 Pfam PF02423 Ornithine cyclodeaminase/mu-crystallin family 2 311 3.0E-135 T 31-10-2018 IPR003462 Ornithine cyclodeaminase/mu-crystallin Reactome: R-HSA-71064 AF_1665 cc60e348a1ea3da3523bfcecf89fff29 322 Gene3D G3DSA:3.40.50.720 122 292 3.5E-137 T 31-10-2018 AF_1665 cc60e348a1ea3da3523bfcecf89fff29 322 SUPERFAMILY SSF51735 1 320 1.1E-107 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1665 cc60e348a1ea3da3523bfcecf89fff29 322 Gene3D G3DSA:3.30.1780.10 6 314 3.5E-137 T 31-10-2018 IPR023401 Ornithine cyclodeaminase, N-terminal Reactome: R-HSA-71064 AF_1665 cc60e348a1ea3da3523bfcecf89fff29 322 TIGRFAM TIGR02371 ala_DH_arch: alanine dehydrogenase 2 320 2.8E-181 T 31-10-2018 IPR012742 Alanine dehydrogenase, Archaeoglobus-type GO:0000286|GO:0006522|GO:0051287 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 AF_1665 cc60e348a1ea3da3523bfcecf89fff29 322 Hamap MF_00935 Alanine dehydrogenase [ala]. 3 318 50.372 T 31-10-2018 IPR028609 Alanine dehydrogenase, archaeal-type GO:0000286|GO:0006522|GO:0051287 KEGG: 00250+1.4.1.1|KEGG: 00430+1.4.1.1 AF_1716 7045be5d64bacd8d1d30bc490d0d21ed 311 SUPERFAMILY SSF53474 38 308 1.5E-73 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_1716 7045be5d64bacd8d1d30bc490d0d21ed 311 Gene3D G3DSA:3.40.50.1820 1 311 6.8E-115 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_1716 7045be5d64bacd8d1d30bc490d0d21ed 311 Pfam PF07859 alpha/beta hydrolase fold 82 288 1.2E-74 T 31-10-2018 IPR013094 Alpha/beta hydrolase fold-3 GO:0016787 AF_0458 ebc4690b2ac866954e605a7eb4e9f93b 446 SUPERFAMILY SSF53738 8 177 1.33E-39 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AF_0458 ebc4690b2ac866954e605a7eb4e9f93b 446 Gene3D G3DSA:3.40.120.10 253 359 1.2E-68 T 31-10-2018 AF_0458 ebc4690b2ac866954e605a7eb4e9f93b 446 Pfam PF02880 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III 257 364 1.1E-24 T 31-10-2018 IPR005846 Alpha-D-phosphohexomutase, alpha/beta/alpha domain III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AF_0458 ebc4690b2ac866954e605a7eb4e9f93b 446 Gene3D G3DSA:3.40.120.10 169 354 1.2E-68 T 31-10-2018 AF_0458 ebc4690b2ac866954e605a7eb4e9f93b 446 TIGRFAM TIGR03990 Arch_GlmM: phosphoglucosamine mutase 8 438 4.7E-176 T 31-10-2018 IPR024086 Phosphoglucosamine mutase, archaeal type GO:0008966 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AF_0458 ebc4690b2ac866954e605a7eb4e9f93b 446 SUPERFAMILY SSF53738 256 362 1.77E-27 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AF_0458 ebc4690b2ac866954e605a7eb4e9f93b 446 Pfam PF00408 Phosphoglucomutase/phosphomannomutase, C-terminal domain 373 433 1.8E-14 T 31-10-2018 IPR005843 Alpha-D-phosphohexomutase, C-terminal GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AF_0458 ebc4690b2ac866954e605a7eb4e9f93b 446 SUPERFAMILY SSF53738 155 255 9.03E-31 T 31-10-2018 IPR016055 Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AF_0458 ebc4690b2ac866954e605a7eb4e9f93b 446 Pfam PF02879 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II 156 252 3.8E-26 T 31-10-2018 IPR005845 Alpha-D-phosphohexomutase, alpha/beta/alpha domain II GO:0005975 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AF_0458 ebc4690b2ac866954e605a7eb4e9f93b 446 SUPERFAMILY SSF55957 355 446 2.09E-22 T 31-10-2018 IPR036900 Alpha-D-phosphohexomutase, C-terminal domain superfamily GO:0016868|GO:0071704 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AF_0458 ebc4690b2ac866954e605a7eb4e9f93b 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 204 217 9.8E-20 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AF_0458 ebc4690b2ac866954e605a7eb4e9f93b 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 232 247 9.8E-20 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AF_0458 ebc4690b2ac866954e605a7eb4e9f93b 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 93 107 9.8E-20 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AF_0458 ebc4690b2ac866954e605a7eb4e9f93b 446 PRINTS PR00509 Phosphoglucomutase/phosphomannomutase family signature 170 189 9.8E-20 T 31-10-2018 IPR005841 Alpha-D-phosphohexomutase superfamily GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AF_0458 ebc4690b2ac866954e605a7eb4e9f93b 446 Gene3D G3DSA:3.40.120.10 7 151 5.5E-46 T 31-10-2018 AF_0458 ebc4690b2ac866954e605a7eb4e9f93b 446 ProSitePatterns PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. 94 103 - T 31-10-2018 IPR016066 Alpha-D-phosphohexomutase, conserved site GO:0000287 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AF_0458 ebc4690b2ac866954e605a7eb4e9f93b 446 Gene3D G3DSA:3.30.310.50 367 446 2.7E-22 T 31-10-2018 AF_0458 ebc4690b2ac866954e605a7eb4e9f93b 446 Pfam PF02878 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I 8 131 2.3E-38 T 31-10-2018 IPR005844 Alpha-D-phosphohexomutase, alpha/beta/alpha domain I GO:0005975|GO:0016868 KEGG: 00520+5.4.2.10|MetaCyc: PWY-6749 AF_0374 e7636e2db5339c55d7586c6d2e396f72 265 Gene3D G3DSA:3.40.50.1000 85 182 2.1E-94 T 31-10-2018 IPR023214 HAD superfamily AF_0374 e7636e2db5339c55d7586c6d2e396f72 265 Pfam PF13344 Haloacid dehalogenase-like hydrolase 9 108 9.5E-22 T 31-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA AF_0374 e7636e2db5339c55d7586c6d2e396f72 265 SUPERFAMILY SSF56784 5 260 1.11E-62 T 31-10-2018 IPR036412 HAD-like superfamily AF_0374 e7636e2db5339c55d7586c6d2e396f72 265 PIRSF PIRSF000915 4 265 2.2E-54 T 31-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA AF_0374 e7636e2db5339c55d7586c6d2e396f72 265 Gene3D G3DSA:3.40.50.1000 8 256 2.1E-94 T 31-10-2018 IPR023214 HAD superfamily AF_0374 e7636e2db5339c55d7586c6d2e396f72 265 Pfam PF13242 HAD-hyrolase-like 182 258 7.2E-18 T 31-10-2018 AF_0374 e7636e2db5339c55d7586c6d2e396f72 265 TIGRFAM TIGR01460 HAD-SF-IIA: HAD hydrolase, family IIA 9 231 1.8E-40 T 31-10-2018 IPR006357 HAD-superfamily hydrolase, subfamily IIA AF_0517 4795ecdb97942ca63182015b487a51e6 586 Gene3D G3DSA:2.40.50.140 2 125 3.0E-39 T 31-10-2018 AF_0517 4795ecdb97942ca63182015b487a51e6 586 SMART SM00350 3 494 1.6E-185 T 31-10-2018 IPR031327 Mini-chromosome maintenance protein AF_0517 4795ecdb97942ca63182015b487a51e6 586 Gene3D G3DSA:1.10.10.10 499 583 4.8E-27 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0517 4795ecdb97942ca63182015b487a51e6 586 Gene3D G3DSA:3.40.50.300 148 498 6.2E-138 T 31-10-2018 AF_0517 4795ecdb97942ca63182015b487a51e6 586 Pfam PF17207 MCM OB domain 2 114 2.2E-28 T 31-10-2018 IPR033762 MCM OB domain Reactome: R-HSA-176187|Reactome: R-HSA-176974|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 AF_0517 4795ecdb97942ca63182015b487a51e6 586 Gene3D G3DSA:2.20.28.10 16 64 3.0E-39 T 31-10-2018 AF_0517 4795ecdb97942ca63182015b487a51e6 586 SMART SM00382 206 358 9.0E-5 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0517 4795ecdb97942ca63182015b487a51e6 586 SUPERFAMILY SSF50249 2 132 1.4E-38 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0517 4795ecdb97942ca63182015b487a51e6 586 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 317 329 5.5E-31 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 AF_0517 4795ecdb97942ca63182015b487a51e6 586 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 293 306 5.5E-31 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 AF_0517 4795ecdb97942ca63182015b487a51e6 586 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 265 279 5.5E-31 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 AF_0517 4795ecdb97942ca63182015b487a51e6 586 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 344 352 5.5E-31 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 AF_0517 4795ecdb97942ca63182015b487a51e6 586 PRINTS PR01657 Mini-chromosome maintenance (MCM) protein family signature 205 220 5.5E-31 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 AF_0517 4795ecdb97942ca63182015b487a51e6 586 Pfam PF00493 MCM2/3/5 family 152 493 1.4E-140 T 31-10-2018 IPR001208 MCM domain GO:0003677|GO:0005524|GO:0006270 AF_0517 4795ecdb97942ca63182015b487a51e6 586 SUPERFAMILY SSF52540 174 507 1.06E-46 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1259 7099eff44e35f67bb691ce5e4143737e 259 Pfam PF02195 ParB-like nuclease domain 114 224 3.2E-14 T 31-10-2018 IPR003115 ParB/Sulfiredoxin AF_1259 7099eff44e35f67bb691ce5e4143737e 259 Gene3D G3DSA:3.10.580.10 1 58 1.5E-16 T 31-10-2018 AF_1259 7099eff44e35f67bb691ce5e4143737e 259 SMART SM00470 147 229 5.4E-15 T 31-10-2018 IPR003115 ParB/Sulfiredoxin AF_1259 7099eff44e35f67bb691ce5e4143737e 259 Gene3D G3DSA:3.10.580.10 59 122 8.0E-15 T 31-10-2018 AF_1259 7099eff44e35f67bb691ce5e4143737e 259 SUPERFAMILY SSF110849 146 227 2.35E-18 T 31-10-2018 IPR036086 ParB/Sulfiredoxin superfamily AF_1259 7099eff44e35f67bb691ce5e4143737e 259 SMART SM00116 12 60 3.8E-9 T 31-10-2018 IPR000644 CBS domain AF_1259 7099eff44e35f67bb691ce5e4143737e 259 SMART SM00116 71 119 8.3E-10 T 31-10-2018 IPR000644 CBS domain AF_1259 7099eff44e35f67bb691ce5e4143737e 259 SUPERFAMILY SSF54631 3 120 1.52E-35 T 31-10-2018 AF_1259 7099eff44e35f67bb691ce5e4143737e 259 PIRSF PIRSF004699 1 259 4.1E-125 T 31-10-2018 IPR016427 Uncharacterised conserved protein UCP004699, CBS/ParB-like AF_1259 7099eff44e35f67bb691ce5e4143737e 259 Pfam PF00571 CBS domain 64 117 8.6E-12 T 31-10-2018 IPR000644 CBS domain AF_1259 7099eff44e35f67bb691ce5e4143737e 259 Pfam PF00571 CBS domain 5 58 2.8E-14 T 31-10-2018 IPR000644 CBS domain AF_1259 7099eff44e35f67bb691ce5e4143737e 259 Gene3D G3DSA:3.90.1530.10 126 230 1.7E-8 T 31-10-2018 AF_1840 0f227c23b9207a0445523666869831b2 291 Hamap MF_01975 Methionine aminopeptidase [map]. 6 290 46.982 T 31-10-2018 IPR028595 Methionine aminopeptidase, archaeal GO:0004177|GO:0006508 MetaCyc: PWY-7799|MetaCyc: PWY-7800 AF_1840 0f227c23b9207a0445523666869831b2 291 Gene3D G3DSA:3.90.230.10 11 281 3.4E-93 T 31-10-2018 AF_1840 0f227c23b9207a0445523666869831b2 291 SUPERFAMILY SSF46785 196 266 4.22E-15 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1840 0f227c23b9207a0445523666869831b2 291 PRINTS PR00599 Methionine aminopeptidase-1 signature 55 68 1.2E-17 T 31-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AF_1840 0f227c23b9207a0445523666869831b2 291 PRINTS PR00599 Methionine aminopeptidase-1 signature 177 189 1.2E-17 T 31-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AF_1840 0f227c23b9207a0445523666869831b2 291 PRINTS PR00599 Methionine aminopeptidase-1 signature 146 158 1.2E-17 T 31-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AF_1840 0f227c23b9207a0445523666869831b2 291 PRINTS PR00599 Methionine aminopeptidase-1 signature 80 96 1.2E-17 T 31-10-2018 IPR001714 Peptidase M24, methionine aminopeptidase MetaCyc: PWY-7799|MetaCyc: PWY-7800 AF_1840 0f227c23b9207a0445523666869831b2 291 Gene3D G3DSA:1.10.10.10 196 267 3.4E-93 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1840 0f227c23b9207a0445523666869831b2 291 SUPERFAMILY SSF55920 2 290 8.77E-65 T 31-10-2018 IPR036005 Creatinase/aminopeptidase-like AF_1840 0f227c23b9207a0445523666869831b2 291 ProSitePatterns PS01202 Methionine aminopeptidase subfamily 2 signature. 80 96 - T 31-10-2018 IPR018349 Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site MetaCyc: PWY-7799|MetaCyc: PWY-7800 AF_1840 0f227c23b9207a0445523666869831b2 291 TIGRFAM TIGR00501 met_pdase_II: methionine aminopeptidase, type II 2 291 7.8E-142 T 31-10-2018 IPR002468 Peptidase M24A, methionine aminopeptidase, subfamily 2 GO:0004177|GO:0006508|GO:0008235 MetaCyc: PWY-7799|MetaCyc: PWY-7800|Reactome: R-HSA-2514859 AF_1840 0f227c23b9207a0445523666869831b2 291 Pfam PF00557 Metallopeptidase family M24 8 282 3.7E-46 T 31-10-2018 IPR000994 Peptidase M24 AF_2424 f54723138528ce030160daa45ed2597e 406 Pfam PF01882 Protein of unknown function DUF58 186 271 1.0E-26 T 31-10-2018 IPR002881 Domain of unknown function DUF58 AF_1664 e2749140456ae9e8223a61171372f74f 752 TIGRFAM TIGR02504 NrdJ_Z: ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent 8 560 9.5E-238 T 31-10-2018 IPR013344 Ribonucleotide reductase, adenosylcobalamin-dependent GO:0000166|GO:0004748|GO:0031419|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227 AF_1664 e2749140456ae9e8223a61171372f74f 752 PRINTS PR01183 Ribonucleotide reductase large chain signature 402 429 1.8E-33 T 31-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AF_1664 e2749140456ae9e8223a61171372f74f 752 PRINTS PR01183 Ribonucleotide reductase large chain signature 296 319 1.8E-33 T 31-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AF_1664 e2749140456ae9e8223a61171372f74f 752 PRINTS PR01183 Ribonucleotide reductase large chain signature 159 178 1.8E-33 T 31-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AF_1664 e2749140456ae9e8223a61171372f74f 752 PRINTS PR01183 Ribonucleotide reductase large chain signature 362 385 1.8E-33 T 31-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AF_1664 e2749140456ae9e8223a61171372f74f 752 PRINTS PR01183 Ribonucleotide reductase large chain signature 334 356 1.8E-33 T 31-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AF_1664 e2749140456ae9e8223a61171372f74f 752 Pfam PF02867 Ribonucleotide reductase, barrel domain 84 550 1.2E-172 T 31-10-2018 IPR000788 Ribonucleotide reductase large subunit, C-terminal GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AF_1664 e2749140456ae9e8223a61171372f74f 752 Gene3D G3DSA:3.20.70.20 1 565 6.8E-254 T 31-10-2018 AF_1664 e2749140456ae9e8223a61171372f74f 752 SUPERFAMILY SSF51998 83 561 7.32E-166 T 31-10-2018 AF_1664 e2749140456ae9e8223a61171372f74f 752 Pfam PF00317 Ribonucleotide reductase, all-alpha domain 3 80 1.4E-28 T 31-10-2018 IPR013509 Ribonucleotide reductase large subunit, N-terminal GO:0004748|GO:0005524|GO:0006260|GO:0055114 KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AF_1664 e2749140456ae9e8223a61171372f74f 752 SUPERFAMILY SSF48168 7 82 7.59E-17 T 31-10-2018 IPR008926 Ribonucleotide reductase R1 subunit, N-terminal KEGG: 00230+1.17.4.1|KEGG: 00240+1.17.4.1|KEGG: 00480+1.17.4.1|KEGG: 00983+1.17.4.1|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210|MetaCyc: PWY-7220|MetaCyc: PWY-7222|MetaCyc: PWY-7226|MetaCyc: PWY-7227|Reactome: R-HSA-499943 AF_1664 e2749140456ae9e8223a61171372f74f 752 Pfam PF12637 TSCPD domain 597 685 6.7E-8 T 31-10-2018 IPR024434 TSCPD domain AF_0396 b41e041c124f3936f9df4a2aa9ddca6d 260 Gene3D G3DSA:1.10.10.10 4 77 5.7E-9 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0396 b41e041c124f3936f9df4a2aa9ddca6d 260 SUPERFAMILY SSF46785 6 155 6.09E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0396 b41e041c124f3936f9df4a2aa9ddca6d 260 Pfam PF01022 Bacterial regulatory protein, arsR family 6 50 3.7E-13 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_0396 b41e041c124f3936f9df4a2aa9ddca6d 260 PIRSF PIRSF006692 1 249 1.3E-67 T 31-10-2018 IPR016490 Transcriptional regulator, HTH, AF0396-type AF_0396 b41e041c124f3936f9df4a2aa9ddca6d 260 Pfam PF08350 Domain of unknown function (DUF1724) 188 240 2.4E-10 T 31-10-2018 IPR013561 Domain of unknown function DUF1724 AF_1989 56843664c7b50df907a4473dc6ad5f4d 253 SUPERFAMILY SSF54534 2 145 1.46E-37 T 31-10-2018 AF_1989 56843664c7b50df907a4473dc6ad5f4d 253 Gene3D G3DSA:2.40.10.330 89 129 8.9E-47 T 31-10-2018 AF_1989 56843664c7b50df907a4473dc6ad5f4d 253 Pfam PF00254 FKBP-type peptidyl-prolyl cis-trans isomerase 3 89 9.1E-12 T 31-10-2018 IPR001179 FKBP-type peptidyl-prolyl cis-trans isomerase domain AF_1989 56843664c7b50df907a4473dc6ad5f4d 253 Gene3D G3DSA:3.10.50.40 5 143 8.9E-47 T 31-10-2018 AF_0815 ade1eeb2d455e856e0183f9dd5d941a5 349 TIGRFAM TIGR00308 TRM1: N2,N2-dimethylguanosine tRNA methyltransferase 3 348 3.9E-151 T 31-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 AF_0815 ade1eeb2d455e856e0183f9dd5d941a5 349 Pfam PF02005 N2,N2-dimethylguanosine tRNA methyltransferase 12 344 1.9E-122 T 31-10-2018 IPR002905 tRNA methyltransferase, Trm1 GO:0003723|GO:0004809|GO:0008033 MetaCyc: PWY-6829 AF_0815 ade1eeb2d455e856e0183f9dd5d941a5 349 Gene3D G3DSA:3.30.56.70 287 346 3.7E-15 T 31-10-2018 AF_0815 ade1eeb2d455e856e0183f9dd5d941a5 349 Gene3D G3DSA:3.40.50.150 1 286 6.2E-81 T 31-10-2018 AF_0815 ade1eeb2d455e856e0183f9dd5d941a5 349 SUPERFAMILY SSF53335 2 344 2.73E-92 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_0815 ade1eeb2d455e856e0183f9dd5d941a5 349 Hamap MF_00290 tRNA (guanine(26)-N(2))-dimethyltransferase [trm1]. 1 345 39.824 T 31-10-2018 IPR022923 tRNA (guanine(26)-N(2))-dimethyltransferase, archaeal and bacterial GO:0004809 MetaCyc: PWY-6829 AF_0710 b4b296ffb7fc0e20227f69277a671a8a 753 ProSitePatterns PS00370 PEP-utilizing enzymes phosphorylation site signature. 393 404 - T 31-10-2018 IPR018274 PEP-utilising enzyme, active site GO:0016310|GO:0016772 AF_0710 b4b296ffb7fc0e20227f69277a671a8a 753 Pfam PF02896 PEP-utilising enzyme, TIM barrel domain 457 742 7.5E-86 T 31-10-2018 IPR000121 PEP-utilising enzyme, C-terminal GO:0016310|GO:0016772 AF_0710 b4b296ffb7fc0e20227f69277a671a8a 753 SUPERFAMILY SSF56059 3 362 8.0E-109 T 31-10-2018 AF_0710 b4b296ffb7fc0e20227f69277a671a8a 753 Pfam PF00391 PEP-utilising enzyme, mobile domain 362 434 2.3E-27 T 31-10-2018 IPR008279 PEP-utilising enzyme, mobile domain GO:0016310|GO:0016772 AF_0710 b4b296ffb7fc0e20227f69277a671a8a 753 PIRSF PIRSF000854 1 747 9.3E-200 T 31-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 AF_0710 b4b296ffb7fc0e20227f69277a671a8a 753 Gene3D G3DSA:3.30.1490.20 2 186 2.9E-79 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AF_0710 b4b296ffb7fc0e20227f69277a671a8a 753 ProSitePatterns PS00742 PEP-utilizing enzymes signature 2. 648 666 - T 31-10-2018 IPR023151 PEP-utilising enzyme, conserved site GO:0016772 AF_0710 b4b296ffb7fc0e20227f69277a671a8a 753 Gene3D G3DSA:3.50.30.10 335 441 3.5E-43 T 31-10-2018 AF_0710 b4b296ffb7fc0e20227f69277a671a8a 753 SUPERFAMILY SSF52009 329 441 1.27E-36 T 31-10-2018 IPR036637 Phosphohistidine domain superfamily GO:0016310|GO:0016772 AF_0710 b4b296ffb7fc0e20227f69277a671a8a 753 TIGRFAM TIGR01418 PEP_synth: phosphoenolpyruvate synthase 3 743 0.0 T 31-10-2018 IPR006319 Phosphoenolpyruvate synthase GO:0006090|GO:0008986 KEGG: 00620+2.7.9.2|KEGG: 00680+2.7.9.2|KEGG: 00720+2.7.9.2|MetaCyc: PWY-5484|MetaCyc: PWY-6142 AF_0710 b4b296ffb7fc0e20227f69277a671a8a 753 SUPERFAMILY SSF51621 450 747 2.07E-89 T 31-10-2018 IPR015813 Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily GO:0003824 AF_0710 b4b296ffb7fc0e20227f69277a671a8a 753 Pfam PF01326 Pyruvate phosphate dikinase, PEP/pyruvate binding domain 15 329 3.3E-120 T 31-10-2018 IPR002192 Pyruvate phosphate dikinase, PEP/pyruvate-binding GO:0005524|GO:0016301|GO:0016310 AF_0710 b4b296ffb7fc0e20227f69277a671a8a 753 Gene3D G3DSA:3.30.470.20 187 334 4.5E-46 T 31-10-2018 AF_0710 b4b296ffb7fc0e20227f69277a671a8a 753 Gene3D G3DSA:3.20.20.60 442 753 1.9E-97 T 31-10-2018 AF_0710 b4b296ffb7fc0e20227f69277a671a8a 753 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 648 663 9.8E-14 T 31-10-2018 AF_0710 b4b296ffb7fc0e20227f69277a671a8a 753 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 485 504 9.8E-14 T 31-10-2018 AF_0710 b4b296ffb7fc0e20227f69277a671a8a 753 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 665 680 9.8E-14 T 31-10-2018 AF_0710 b4b296ffb7fc0e20227f69277a671a8a 753 PRINTS PR01736 Phosphoenolpyruvate-protein phosphotransferase signature 701 713 9.8E-14 T 31-10-2018 AF_0620 1c490d551d5de367cb92811bae268912 297 Pfam PF00535 Glycosyl transferase family 2 4 166 9.2E-27 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AF_0620 1c490d551d5de367cb92811bae268912 297 SUPERFAMILY SSF53448 1 257 1.41E-39 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0620 1c490d551d5de367cb92811bae268912 297 Gene3D G3DSA:3.90.550.10 1 222 8.7E-38 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_2375 a76cfe3c5a8adb9d3dac8d1a101ffa92 506 Pfam PF00404 Dockerin type I repeat 437 451 1.7E-4 T 31-10-2018 IPR002105 Dockerin type I repeat GO:0000272|GO:0004553 AF_2375 a76cfe3c5a8adb9d3dac8d1a101ffa92 506 SUPERFAMILY SSF49384 280 374 1.13E-14 T 31-10-2018 IPR008965 CBM2/CBM3, carbohydrate-binding domain superfamily GO:0030246 AF_2375 a76cfe3c5a8adb9d3dac8d1a101ffa92 506 Gene3D G3DSA:2.60.40.680 277 434 3.6E-52 T 31-10-2018 AF_2375 a76cfe3c5a8adb9d3dac8d1a101ffa92 506 SUPERFAMILY SSF63446 435 489 1.47E-9 T 31-10-2018 IPR036439 Dockerin domain superfamily GO:0000272 AF_2375 a76cfe3c5a8adb9d3dac8d1a101ffa92 506 Pfam PF00963 Cohesin domain 280 418 2.8E-24 T 31-10-2018 IPR002102 Cellulosome anchoring protein, cohesin domain GO:0000272|GO:0030246 AF_2375 a76cfe3c5a8adb9d3dac8d1a101ffa92 506 Pfam PF07676 WD40-like Beta Propeller Repeat 92 111 0.031 T 31-10-2018 IPR011659 WD40-like Beta Propeller AF_2375 a76cfe3c5a8adb9d3dac8d1a101ffa92 506 SUPERFAMILY SSF69304 74 250 1.83E-11 T 31-10-2018 AF_2375 a76cfe3c5a8adb9d3dac8d1a101ffa92 506 Gene3D G3DSA:1.10.1330.10 435 496 3.5E-10 T 31-10-2018 AF_2375 a76cfe3c5a8adb9d3dac8d1a101ffa92 506 Gene3D G3DSA:2.120.10.30 9 259 5.1E-8 T 31-10-2018 IPR011042 Six-bladed beta-propeller, TolB-like AF_0502 4698d19a445ae192d0ee2d8909150e9e 555 Pfam PF13183 4Fe-4S dicluster domain 89 174 1.7E-9 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0502 4698d19a445ae192d0ee2d8909150e9e 555 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 160 171 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0502 4698d19a445ae192d0ee2d8909150e9e 555 SUPERFAMILY SSF46548 80 189 1.1E-15 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_0502 4698d19a445ae192d0ee2d8909150e9e 555 Pfam PF02754 Cysteine-rich domain 412 498 2.8E-5 T 31-10-2018 IPR004017 Cysteine-rich domain AF_0633 179669de2d8f732b737439f5d44218ec 1018 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 386 401 9.4E-32 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AF_0633 179669de2d8f732b737439f5d44218ec 1018 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 36 47 9.4E-32 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AF_0633 179669de2d8f732b737439f5d44218ec 1018 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 214 237 9.4E-32 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AF_0633 179669de2d8f732b737439f5d44218ec 1018 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 545 554 9.4E-32 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AF_0633 179669de2d8f732b737439f5d44218ec 1018 PRINTS PR00984 Isoleucyl-tRNA synthetase signature 506 519 9.4E-32 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AF_0633 179669de2d8f732b737439f5d44218ec 1018 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 43 54 - T 31-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_0633 179669de2d8f732b737439f5d44218ec 1018 Pfam PF00133 tRNA synthetases class I (I, L, M and V) 15 625 4.2E-198 T 31-10-2018 IPR002300 Aminoacyl-tRNA synthetase, class Ia GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_0633 179669de2d8f732b737439f5d44218ec 1018 SUPERFAMILY SSF52374 3 633 1.71E-141 T 31-10-2018 AF_0633 179669de2d8f732b737439f5d44218ec 1018 SUPERFAMILY SSF50677 192 388 1.05E-53 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AF_0633 179669de2d8f732b737439f5d44218ec 1018 Gene3D G3DSA:3.90.740.10 190 392 4.3E-242 T 31-10-2018 IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain GO:0002161|GO:0006418 AF_0633 179669de2d8f732b737439f5d44218ec 1018 Gene3D G3DSA:1.10.730.10 629 809 1.2E-47 T 31-10-2018 AF_0633 179669de2d8f732b737439f5d44218ec 1018 Gene3D G3DSA:3.40.50.620 12 612 4.3E-242 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_0633 179669de2d8f732b737439f5d44218ec 1018 Pfam PF08264 Anticodon-binding domain of tRNA 667 817 1.6E-35 T 31-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AF_0633 179669de2d8f732b737439f5d44218ec 1018 SUPERFAMILY SSF47323 637 865 1.05E-53 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_0633 179669de2d8f732b737439f5d44218ec 1018 TIGRFAM TIGR00392 ileS: isoleucine--tRNA ligase 3 833 0.0 T 31-10-2018 IPR002301 Isoleucine-tRNA ligase GO:0000166|GO:0004822|GO:0005524|GO:0005737|GO:0006428 KEGG: 00970+6.1.1.5 AF_0633 179669de2d8f732b737439f5d44218ec 1018 Hamap MF_02003 Isoleucine--tRNA ligase [ileS]. 2 1010 13.421 T 31-10-2018 IPR023586 Isoleucine-tRNA ligase, type 2 GO:0004822 KEGG: 00970+6.1.1.5|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AF_1765 fd8272fdcf5400064e833a3f4e2344fe 250 Gene3D G3DSA:3.20.20.140 1 249 6.6E-59 T 31-10-2018 AF_1765 fd8272fdcf5400064e833a3f4e2344fe 250 SUPERFAMILY SSF51556 1 247 1.84E-31 T 31-10-2018 IPR032466 Metal-dependent hydrolase AF_1765 fd8272fdcf5400064e833a3f4e2344fe 250 Pfam PF01026 TatD related DNase 3 246 1.5E-18 T 31-10-2018 IPR001130 TatD family GO:0016788 AF_1765 fd8272fdcf5400064e833a3f4e2344fe 250 PIRSF PIRSF005295 1 250 3.7E-99 T 31-10-2018 IPR012022 Protein of unknown function UCP005295 AF_1906 bc6b49388bbd17790ac3f0c85ea402c2 189 SUPERFAMILY SSF53137 4 185 5.76E-61 T 31-10-2018 AF_1906 bc6b49388bbd17790ac3f0c85ea402c2 189 Hamap MF_01337_A 50S ribosomal protein L18 [rplR]. 7 185 43.474 T 31-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1906 bc6b49388bbd17790ac3f0c85ea402c2 189 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 102 135 2.7E-9 T 31-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1906 bc6b49388bbd17790ac3f0c85ea402c2 189 Pfam PF17144 Ribosomal large subunit proteins 60S L5, and 50S L18 8 98 4.0E-23 T 31-10-2018 IPR005485 Ribosomal protein L5 eukaryotic/L18 archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412|GO:0008097 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1906 bc6b49388bbd17790ac3f0c85ea402c2 189 Gene3D G3DSA:3.30.420.100 3 188 1.7E-69 T 31-10-2018 AF_0734 fd083acd0dbf9a047e65fbf264501fa8 219 Gene3D G3DSA:3.40.1280.10 1 219 2.2E-93 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AF_0734 fd083acd0dbf9a047e65fbf264501fa8 219 Hamap MF_00554 Ribosomal RNA small subunit methyltransferase Nep1 [nep1]. 3 212 38.367 T 31-10-2018 IPR023503 Ribosome biogenesis methyltransferase NEP1, archaea GO:0008168 AF_0734 fd083acd0dbf9a047e65fbf264501fa8 219 Pfam PF03587 EMG1/NEP1 methyltransferase 6 211 4.7E-44 T 31-10-2018 IPR005304 Ribosomal biogenesis, methyltransferase, EMG1/NEP1 GO:0008168 Reactome: R-HSA-6790901|Reactome: R-HSA-6791226 AF_0734 fd083acd0dbf9a047e65fbf264501fa8 219 SUPERFAMILY SSF75217 5 211 2.49E-54 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases AF_0985 2d35aa819f726b820ec9c5ac91c0d144 178 Hamap MF_00076 Imidazoleglycerol-phosphate dehydratase [hisB]. 2 177 30.127 T 31-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AF_0985 2d35aa819f726b820ec9c5ac91c0d144 178 SUPERFAMILY SSF54211 3 70 5.69E-20 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AF_0985 2d35aa819f726b820ec9c5ac91c0d144 178 Pfam PF00475 Imidazoleglycerol-phosphate dehydratase 25 159 9.8E-43 T 31-10-2018 IPR000807 Imidazoleglycerol-phosphate dehydratase GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AF_0985 2d35aa819f726b820ec9c5ac91c0d144 178 Gene3D G3DSA:3.30.230.40 79 177 3.1E-24 T 31-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 AF_0985 2d35aa819f726b820ec9c5ac91c0d144 178 Gene3D G3DSA:3.30.230.40 4 75 1.8E-26 T 31-10-2018 IPR038494 Imidazole glycerol phosphate dehydratase domain superfamily KEGG: 00340+4.2.1.19 AF_0985 2d35aa819f726b820ec9c5ac91c0d144 178 SUPERFAMILY SSF54211 76 163 7.71E-22 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AF_0985 2d35aa819f726b820ec9c5ac91c0d144 178 ProSitePatterns PS00955 Imidazoleglycerol-phosphate dehydratase signature 2. 141 153 - T 31-10-2018 IPR020565 Imidazoleglycerol-phosphate dehydratase, conserved site GO:0000105|GO:0004424 KEGG: 00340+4.2.1.19 AF_1752 fe4d39929a03411a04ebf0202b89b66e 493 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 262 444 1.3E-35 T 31-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 AF_1752 fe4d39929a03411a04ebf0202b89b66e 493 PIRSF PIRSF000538 8 492 7.1E-144 T 31-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AF_1752 fe4d39929a03411a04ebf0202b89b66e 493 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 358 378 - T 31-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AF_1752 fe4d39929a03411a04ebf0202b89b66e 493 Gene3D G3DSA:3.30.420.40 249 492 4.8E-70 T 31-10-2018 AF_1752 fe4d39929a03411a04ebf0202b89b66e 493 Gene3D G3DSA:3.30.420.40 8 248 1.6E-91 T 31-10-2018 AF_1752 fe4d39929a03411a04ebf0202b89b66e 493 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 11 251 1.3E-71 T 31-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 AF_1752 fe4d39929a03411a04ebf0202b89b66e 493 TIGRFAM TIGR01312 XylB: xylulokinase 11 486 7.3E-115 T 31-10-2018 IPR006000 Xylulokinase GO:0004856|GO:0005997 KEGG: 00040+2.7.1.17 AF_1752 fe4d39929a03411a04ebf0202b89b66e 493 SUPERFAMILY SSF53067 9 255 2.41E-83 T 31-10-2018 AF_1752 fe4d39929a03411a04ebf0202b89b66e 493 SUPERFAMILY SSF53067 254 489 5.99E-61 T 31-10-2018 AF_2138 4182aa9a0b1956508dfdd8d977ce1e09 344 TIGRFAM TIGR00338 serB: phosphoserine phosphatase SerB 116 334 7.0E-96 T 31-10-2018 AF_2138 4182aa9a0b1956508dfdd8d977ce1e09 344 Pfam PF12710 haloacid dehalogenase-like hydrolase 132 298 2.5E-24 T 31-10-2018 AF_2138 4182aa9a0b1956508dfdd8d977ce1e09 344 Gene3D G3DSA:1.10.150.210 141 201 6.9E-78 T 31-10-2018 IPR023190 Phosphoserine phosphatase, domain 2 GO:0004647|GO:0006564 KEGG: 00260+3.1.3.3|KEGG: 00680+3.1.3.3|Reactome: R-HSA-977347 AF_2138 4182aa9a0b1956508dfdd8d977ce1e09 344 Gene3D G3DSA:3.30.70.260 43 124 2.1E-17 T 31-10-2018 AF_2138 4182aa9a0b1956508dfdd8d977ce1e09 344 Gene3D G3DSA:3.40.50.1000 130 322 6.9E-78 T 31-10-2018 IPR023214 HAD superfamily AF_2138 4182aa9a0b1956508dfdd8d977ce1e09 344 Pfam PF13740 ACT domain 48 120 2.4E-10 T 31-10-2018 AF_2138 4182aa9a0b1956508dfdd8d977ce1e09 344 SUPERFAMILY SSF56784 126 335 4.94E-55 T 31-10-2018 IPR036412 HAD-like superfamily AF_2138 4182aa9a0b1956508dfdd8d977ce1e09 344 SUPERFAMILY SSF55021 44 126 1.86E-15 T 31-10-2018 AF_2138 4182aa9a0b1956508dfdd8d977ce1e09 344 TIGRFAM TIGR01488 HAD-SF-IB: HAD phosphoserine phosphatase-like hydrolase, family IB 131 302 4.5E-39 T 31-10-2018 AF_1075 4f5a2d7e3dde4c8ab50835d6c8fc8096 92 Gene3D G3DSA:3.30.2310.20 3 92 5.1E-18 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AF_1075 4f5a2d7e3dde4c8ab50835d6c8fc8096 92 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 5 85 3.4E-7 T 31-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family AF_1075 4f5a2d7e3dde4c8ab50835d6c8fc8096 92 SUPERFAMILY SSF143011 1 91 2.62E-17 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AF_1674 df223f7a131167b7e26bdd927a055a6a 351 Pfam PF13685 Iron-containing alcohol dehydrogenase 13 268 3.4E-72 T 31-10-2018 IPR032837 Glycerol-1-phosphate dehydrogenase KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 AF_1674 df223f7a131167b7e26bdd927a055a6a 351 Gene3D G3DSA:3.40.50.1970 1 155 3.4E-33 T 31-10-2018 AF_1674 df223f7a131167b7e26bdd927a055a6a 351 Gene3D G3DSA:1.20.1090.10 156 350 2.8E-51 T 31-10-2018 AF_1674 df223f7a131167b7e26bdd927a055a6a 351 Hamap MF_00497_A Glycerol-1-phosphate dehydrogenase [NAD(P)+] [egsA]. 5 351 40.027 T 31-10-2018 IPR023002 Glycerol-1-phosphate dehydrogenase, archaea GO:0050492|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 AF_1674 df223f7a131167b7e26bdd927a055a6a 351 SUPERFAMILY SSF56796 3 336 2.88E-63 T 31-10-2018 AF_1674 df223f7a131167b7e26bdd927a055a6a 351 PIRSF PIRSF000112 2 347 1.6E-61 T 31-10-2018 IPR016205 Glycerol dehydrogenase GO:0016614|GO:0046872|GO:0055114 KEGG: 00564+1.1.1.261|MetaCyc: PWY-6349 AF_1484 f61c73a54d3f49ef8b1a4893fe3f9b87 53 Pfam PF06745 KaiC 3 50 1.3E-15 T 31-10-2018 IPR014774 KaiC-like domain AF_1484 f61c73a54d3f49ef8b1a4893fe3f9b87 53 Gene3D G3DSA:3.40.50.300 1 52 1.5E-15 T 31-10-2018 AF_1484 f61c73a54d3f49ef8b1a4893fe3f9b87 53 SUPERFAMILY SSF52540 2 45 8.46E-13 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1804 c0ea308a7037bb597c2ecacf853f2b87 258 Gene3D G3DSA:1.10.510.10 157 258 1.3E-28 T 31-10-2018 AF_1804 c0ea308a7037bb597c2ecacf853f2b87 258 ProSitePatterns PS01245 RIO1/ZK632.3/MJ0444 family signature. 192 203 - T 31-10-2018 IPR018935 RIO kinase, conserved site GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 AF_1804 c0ea308a7037bb597c2ecacf853f2b87 258 Pfam PF01163 RIO1 family 62 250 2.0E-64 T 31-10-2018 AF_1804 c0ea308a7037bb597c2ecacf853f2b87 258 SUPERFAMILY SSF56112 52 240 1.5E-22 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily AF_1804 c0ea308a7037bb597c2ecacf853f2b87 258 Gene3D G3DSA:3.30.200.20 48 151 2.9E-11 T 31-10-2018 AF_1804 c0ea308a7037bb597c2ecacf853f2b87 258 SMART SM00090 20 257 5.7E-135 T 31-10-2018 IPR000687 RIO kinase GO:0004674|GO:0005524 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6791226 AF_0554 5a2f71e5775d998eb878bb835ce22b50 88 SUPERFAMILY SSF64307 8 87 5.89E-25 T 31-10-2018 IPR036868 TusA-like domain superfamily AF_0554 5a2f71e5775d998eb878bb835ce22b50 88 Pfam PF01206 Sulfurtransferase TusA 18 87 1.6E-24 T 31-10-2018 IPR001455 TusA-like domain AF_0554 5a2f71e5775d998eb878bb835ce22b50 88 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 19 43 - T 31-10-2018 IPR001455 TusA-like domain AF_0554 5a2f71e5775d998eb878bb835ce22b50 88 Gene3D G3DSA:3.30.110.40 15 87 1.1E-25 T 31-10-2018 IPR036868 TusA-like domain superfamily AF_1130 4d09546082fd7478a5dd29c6ec43b0b9 76 Gene3D G3DSA:1.10.10.60 12 73 1.2E-27 T 31-10-2018 AF_1130 4d09546082fd7478a5dd29c6ec43b0b9 76 ProSitePatterns PS01112 RNA polymerases N / 8 Kd subunits signature. 11 20 - T 31-10-2018 IPR020789 RNA polymerases, subunit N, zinc binding site GO:0003677|GO:0003899|GO:0006351|GO:0008270 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AF_1130 4d09546082fd7478a5dd29c6ec43b0b9 76 SUPERFAMILY SSF46924 12 71 5.49E-24 T 31-10-2018 IPR023580 RNA polymerase subunit RPB10 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AF_1130 4d09546082fd7478a5dd29c6ec43b0b9 76 PIRSF PIRSF005653 10 76 4.3E-32 T 31-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AF_1130 4d09546082fd7478a5dd29c6ec43b0b9 76 Hamap MF_00250 DNA-directed RNA polymerase subunit N [rpoN]. 10 72 25.426 T 31-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AF_1130 4d09546082fd7478a5dd29c6ec43b0b9 76 ProDom PD006539 RNA POLYMERASE DNA-DIRECTED SUBUNIT TRANSFERASE NUCLEOTIDYLTRANSFERASE METAL-BINDING ZINC TRANSCRIPTION N 18 57 5.0E-17 T 31-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AF_1130 4d09546082fd7478a5dd29c6ec43b0b9 76 Pfam PF01194 RNA polymerases N / 8 kDa subunit 12 68 3.4E-27 T 31-10-2018 IPR000268 DNA-directed RNA polymerase, subunit N/Rpb10 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AF_0061 4aecb4eb2b73f44bfa4848c584bf0da1 196 Gene3D G3DSA:3.40.50.300 1 192 1.1E-61 T 31-10-2018 AF_0061 4aecb4eb2b73f44bfa4848c584bf0da1 196 Hamap MF_00165 Thymidylate kinase [tmk]. 1 189 24.595 T 31-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AF_0061 4aecb4eb2b73f44bfa4848c584bf0da1 196 SUPERFAMILY SSF52540 1 192 2.06E-46 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0061 4aecb4eb2b73f44bfa4848c584bf0da1 196 TIGRFAM TIGR00041 DTMP_kinase: dTMP kinase 1 181 1.4E-61 T 31-10-2018 IPR018094 Thymidylate kinase GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AF_0061 4aecb4eb2b73f44bfa4848c584bf0da1 196 ProSitePatterns PS01331 Thymidylate kinase signature. 85 97 - T 31-10-2018 IPR018095 Thymidylate kinase, conserved site GO:0004798|GO:0005524|GO:0006233 KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AF_0061 4aecb4eb2b73f44bfa4848c584bf0da1 196 Pfam PF02223 Thymidylate kinase 5 181 7.3E-57 T 31-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 AF_2331 9798c501ba170c88f1a280f29ae52baa 92 SUPERFAMILY SSF143995 1 92 2.09E-58 T 31-10-2018 IPR036842 AF2331-like superfamily AF_2331 9798c501ba170c88f1a280f29ae52baa 92 Gene3D G3DSA:3.30.1970.10 1 92 1.2E-49 T 31-10-2018 IPR036842 AF2331-like superfamily AF_2331 9798c501ba170c88f1a280f29ae52baa 92 Pfam PF14556 AF2331-like 1 90 1.6E-45 T 31-10-2018 IPR028986 AF2331-like domain AF_0387 f3fcbfb32966ef733b2d2ab3ec369017 305 SUPERFAMILY SSF53448 1 251 2.42E-42 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0387 f3fcbfb32966ef733b2d2ab3ec369017 305 Gene3D G3DSA:3.90.550.10 1 225 4.3E-51 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0387 f3fcbfb32966ef733b2d2ab3ec369017 305 Pfam PF00535 Glycosyl transferase family 2 4 156 4.2E-24 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AF_0387 f3fcbfb32966ef733b2d2ab3ec369017 305 TIGRFAM TIGR04182 glyco_TIGR04182: glycosyltransferase, TIGR04182 family 2 290 4.9E-124 T 31-10-2018 IPR026456 Glycosyltransferase AglJ GO:0016757 AF_1354 0607e97481242135ce08a9e072a59944 305 Pfam PF13462 Thioredoxin 130 299 1.4E-34 T 31-10-2018 IPR012336 Thioredoxin-like fold AF_1354 0607e97481242135ce08a9e072a59944 305 Gene3D G3DSA:3.40.30.10 114 304 8.2E-57 T 31-10-2018 AF_1354 0607e97481242135ce08a9e072a59944 305 SUPERFAMILY SSF52833 127 301 1.11E-44 T 31-10-2018 IPR036249 Thioredoxin-like superfamily AF_2204 3aef932a1b34fdbe5f634278bf965ccb 412 Gene3D G3DSA:3.20.20.70 52 391 7.3E-59 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_2204 3aef932a1b34fdbe5f634278bf965ccb 412 SMART SM00729 54 247 0.0018 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AF_2204 3aef932a1b34fdbe5f634278bf965ccb 412 PIRSF PIRSF037420 42 388 5.5E-32 T 31-10-2018 IPR017200 Coenzyme PQQ synthesis protein E AF_2204 3aef932a1b34fdbe5f634278bf965ccb 412 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 287 375 1.3E-12 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain AF_2204 3aef932a1b34fdbe5f634278bf965ccb 412 Pfam PF13353 4Fe-4S single cluster domain 62 119 1.0E-4 T 31-10-2018 AF_2204 3aef932a1b34fdbe5f634278bf965ccb 412 SUPERFAMILY SSF102114 53 357 1.19E-47 T 31-10-2018 AF_2204 3aef932a1b34fdbe5f634278bf965ccb 412 TIGRFAM TIGR04163 rSAM_cobopep: peptide-modifying radical SAM enzyme CbpB 2 398 5.8E-188 T 31-10-2018 IPR026423 Peptide-modifying radical SAM enzyme CbpB AF_2204 3aef932a1b34fdbe5f634278bf965ccb 412 Pfam PF04055 Radical SAM superfamily 58 211 9.5E-20 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_1340 2935a9c70112f2f6f5ba5164479e6c06 372 PIRSF PIRSF001369 1 372 9.7E-138 T 31-10-2018 IPR024176 Citrate synthase, bacterial-type AF_1340 2935a9c70112f2f6f5ba5164479e6c06 372 SUPERFAMILY SSF48256 3 372 7.72E-129 T 31-10-2018 IPR036969 Citrate synthase superfamily GO:0046912 AF_1340 2935a9c70112f2f6f5ba5164479e6c06 372 Gene3D G3DSA:1.10.230.10 221 319 4.0E-125 T 31-10-2018 IPR016143 Citrate synthase-like, small alpha subdomain AF_1340 2935a9c70112f2f6f5ba5164479e6c06 372 Gene3D G3DSA:1.10.580.10 27 352 4.0E-125 T 31-10-2018 IPR016142 Citrate synthase-like, large alpha subdomain Reactome: R-HSA-1268020|Reactome: R-HSA-71403 AF_1340 2935a9c70112f2f6f5ba5164479e6c06 372 Pfam PF00285 Citrate synthase, C-terminal domain 4 355 1.1E-124 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 AF_1340 2935a9c70112f2f6f5ba5164479e6c06 372 TIGRFAM TIGR01800 cit_synth_II: 2-methylcitrate synthase/citrate synthase II 3 372 4.4E-171 T 31-10-2018 IPR011278 2-methylcitrate synthase/citrate synthase type I GO:0005737|GO:0046912 AF_1340 2935a9c70112f2f6f5ba5164479e6c06 372 PRINTS PR00143 Citrate synthase signature 325 339 2.0E-38 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 AF_1340 2935a9c70112f2f6f5ba5164479e6c06 372 PRINTS PR00143 Citrate synthase signature 195 223 2.0E-38 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 AF_1340 2935a9c70112f2f6f5ba5164479e6c06 372 PRINTS PR00143 Citrate synthase signature 124 137 2.0E-38 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 AF_1340 2935a9c70112f2f6f5ba5164479e6c06 372 PRINTS PR00143 Citrate synthase signature 173 188 2.0E-38 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 AF_1340 2935a9c70112f2f6f5ba5164479e6c06 372 PRINTS PR00143 Citrate synthase signature 248 268 2.0E-38 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 AF_1340 2935a9c70112f2f6f5ba5164479e6c06 372 PRINTS PR00143 Citrate synthase signature 305 321 2.0E-38 T 31-10-2018 IPR002020 Citrate synthase GO:0046912 AF_0220 dd44e007e4683c95569b1670574efd1e 506 SMART SM00878 334 439 8.7E-64 T 31-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AF_0220 dd44e007e4683c95569b1670574efd1e 506 SUPERFAMILY SSF52440 1 111 1.29E-49 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AF_0220 dd44e007e4683c95569b1670574efd1e 506 SUPERFAMILY SSF56059 83 350 1.24E-72 T 31-10-2018 AF_0220 dd44e007e4683c95569b1670574efd1e 506 Pfam PF00289 Biotin carboxylase, N-terminal domain 1 110 1.7E-46 T 31-10-2018 IPR005481 Biotin carboxylase-like, N-terminal domain Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AF_0220 dd44e007e4683c95569b1670574efd1e 506 ProSitePatterns PS00866 Carbamoyl-phosphate synthase subdomain signature 1. 152 166 - T 31-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AF_0220 dd44e007e4683c95569b1670574efd1e 506 Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain 116 321 3.5E-75 T 31-10-2018 IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain GO:0005524 AF_0220 dd44e007e4683c95569b1670574efd1e 506 TIGRFAM TIGR00514 accC: acetyl-CoA carboxylase, biotin carboxylase subunit 1 442 3.6E-197 T 31-10-2018 IPR004549 Acetyl-CoA carboxylase, biotin carboxylase GO:0016874 AF_0220 dd44e007e4683c95569b1670574efd1e 506 Pfam PF02785 Biotin carboxylase C-terminal domain 334 440 4.1E-40 T 31-10-2018 IPR005482 Biotin carboxylase, C-terminal Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AF_0220 dd44e007e4683c95569b1670574efd1e 506 SUPERFAMILY SSF51246 329 441 1.2E-43 T 31-10-2018 IPR011054 Rudiment single hybrid motif Reactome: R-HSA-196780 AF_0220 dd44e007e4683c95569b1670574efd1e 506 Gene3D G3DSA:3.30.470.130 1 446 4.1E-192 T 31-10-2018 AF_1600 226721f87a2ddd7b1dfc1bdf2811c2e8 397 Gene3D G3DSA:3.40.50.1100 17 212 3.4E-188 T 31-10-2018 AF_1600 226721f87a2ddd7b1dfc1bdf2811c2e8 397 Hamap MF_00133 Tryptophan synthase beta chain [trpB]. 5 396 53.406 T 31-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AF_1600 226721f87a2ddd7b1dfc1bdf2811c2e8 397 Gene3D G3DSA:3.40.50.1100 61 389 3.4E-188 T 31-10-2018 AF_1600 226721f87a2ddd7b1dfc1bdf2811c2e8 397 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 59 383 4.0E-49 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AF_1600 226721f87a2ddd7b1dfc1bdf2811c2e8 397 PIRSF PIRSF001413 7 397 6.3E-166 T 31-10-2018 IPR023026 Tryptophan synthase beta chain/beta chain-like GO:0000162|GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AF_1600 226721f87a2ddd7b1dfc1bdf2811c2e8 397 SUPERFAMILY SSF53686 15 393 1.44E-148 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AF_1600 226721f87a2ddd7b1dfc1bdf2811c2e8 397 TIGRFAM TIGR00263 trpB: tryptophan synthase, beta subunit 15 394 4.8E-194 T 31-10-2018 IPR006654 Tryptophan synthase, beta chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AF_1600 226721f87a2ddd7b1dfc1bdf2811c2e8 397 ProSitePatterns PS00168 Tryptophan synthase beta chain pyridoxal-phosphate attachment site. 87 101 - T 31-10-2018 IPR006653 Tryptophan synthase, beta chain, conserved site GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AF_0687 0a56dea0b937051802366e76b0dee9c1 549 ProSitePatterns PS00455 Putative AMP-binding domain signature. 199 210 - T 31-10-2018 IPR020845 AMP-binding, conserved site AF_0687 0a56dea0b937051802366e76b0dee9c1 549 Gene3D G3DSA:3.40.50.12780 13 443 8.3E-100 T 31-10-2018 AF_0687 0a56dea0b937051802366e76b0dee9c1 549 Gene3D G3DSA:3.30.300.310 444 549 2.0E-34 T 31-10-2018 AF_0687 0a56dea0b937051802366e76b0dee9c1 549 SUPERFAMILY SSF56801 22 546 4.45E-148 T 31-10-2018 AF_0687 0a56dea0b937051802366e76b0dee9c1 549 Pfam PF13193 AMP-binding enzyme C-terminal domain 456 533 3.1E-21 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AF_0687 0a56dea0b937051802366e76b0dee9c1 549 Pfam PF00501 AMP-binding enzyme 35 447 1.2E-100 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_0748 f52d30584a129dccc6b8355116935a21 299 SUPERFAMILY SSF111331 2 294 3.66E-18 T 31-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily AF_0748 f52d30584a129dccc6b8355116935a21 299 Pfam PF01513 ATP-NAD kinase 2 118 6.7E-8 T 31-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AF_0748 f52d30584a129dccc6b8355116935a21 299 Gene3D G3DSA:3.40.50.10330 1 110 1.3E-8 T 31-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 AF_2075 a222234d3cd70aea9d4d8faec2df425d 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 164 181 6.2E-40 T 31-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AF_2075 a222234d3cd70aea9d4d8faec2df425d 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 35 56 6.2E-40 T 31-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AF_2075 a222234d3cd70aea9d4d8faec2df425d 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 22 29 6.2E-40 T 31-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AF_2075 a222234d3cd70aea9d4d8faec2df425d 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 92 109 6.2E-40 T 31-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AF_2075 a222234d3cd70aea9d4d8faec2df425d 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 122 136 6.2E-40 T 31-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AF_2075 a222234d3cd70aea9d4d8faec2df425d 268 PRINTS PR01099 Hydroxyethylthiazole kinase family signature 66 74 6.2E-40 T 31-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AF_2075 a222234d3cd70aea9d4d8faec2df425d 268 PIRSF PIRSF000513 2 267 2.0E-100 T 31-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AF_2075 a222234d3cd70aea9d4d8faec2df425d 268 Pfam PF02110 Hydroxyethylthiazole kinase family 14 256 6.2E-98 T 31-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AF_2075 a222234d3cd70aea9d4d8faec2df425d 268 Gene3D G3DSA:3.40.1190.20 2 266 2.2E-88 T 31-10-2018 IPR029056 Ribokinase-like AF_2075 a222234d3cd70aea9d4d8faec2df425d 268 TIGRFAM TIGR00694 thiM: hydroxyethylthiazole kinase 14 258 2.0E-101 T 31-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AF_2075 a222234d3cd70aea9d4d8faec2df425d 268 SUPERFAMILY SSF53613 12 264 4.37E-57 T 31-10-2018 IPR029056 Ribokinase-like AF_2075 a222234d3cd70aea9d4d8faec2df425d 268 Hamap MF_00228 Hydroxyethylthiazole kinase [thiM]. 16 259 30.124 T 31-10-2018 IPR000417 Hydroxyethylthiazole kinase GO:0004417|GO:0009228 KEGG: 00730+2.7.1.50|MetaCyc: PWY-6897|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AF_0324 4214e02f78b7b81c4daa017bae8c41bd 332 Pfam PF16363 GDP-mannose 4,6 dehydratase 4 303 1.7E-85 T 31-10-2018 IPR016040 NAD(P)-binding domain AF_0324 4214e02f78b7b81c4daa017bae8c41bd 332 TIGRFAM TIGR01181 dTDP_gluc_dehyt: dTDP-glucose 4,6-dehydratase 2 317 5.0E-163 T 31-10-2018 IPR005888 dTDP-glucose 4,6-dehydratase GO:0008460|GO:0009225 KEGG: 00521+4.2.1.46|KEGG: 00523+4.2.1.46|KEGG: 00525+4.2.1.46|MetaCyc: PWY-3221|MetaCyc: PWY-6808|MetaCyc: PWY-6942|MetaCyc: PWY-6953|MetaCyc: PWY-6973|MetaCyc: PWY-6974|MetaCyc: PWY-6976|MetaCyc: PWY-7104|MetaCyc: PWY-7301|MetaCyc: PWY-7312|MetaCyc: PWY-7315|MetaCyc: PWY-7316|MetaCyc: PWY-7318|MetaCyc: PWY-7413|MetaCyc: PWY-7414|MetaCyc: PWY-7440|MetaCyc: PWY-7657|MetaCyc: PWY-7688|MetaCyc: PWY-7814 AF_0324 4214e02f78b7b81c4daa017bae8c41bd 332 SUPERFAMILY SSF51735 1 319 3.95E-99 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0324 4214e02f78b7b81c4daa017bae8c41bd 332 Gene3D G3DSA:3.90.25.10 176 308 1.0E-131 T 31-10-2018 AF_0324 4214e02f78b7b81c4daa017bae8c41bd 332 Gene3D G3DSA:3.40.50.720 4 293 1.0E-131 T 31-10-2018 AF_0271 1e55a6eaf7f06c444fb27aa42ef99489 271 Pfam PF00037 4Fe-4S binding domain 10 31 1.5E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0271 1e55a6eaf7f06c444fb27aa42ef99489 271 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 16 27 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0271 1e55a6eaf7f06c444fb27aa42ef99489 271 Gene3D G3DSA:3.30.70.20 4 68 1.3E-9 T 31-10-2018 AF_0271 1e55a6eaf7f06c444fb27aa42ef99489 271 SUPERFAMILY SSF54862 5 64 7.3E-14 T 31-10-2018 AF_0271 1e55a6eaf7f06c444fb27aa42ef99489 271 Pfam PF02754 Cysteine-rich domain 123 214 2.4E-18 T 31-10-2018 IPR004017 Cysteine-rich domain AF_1602 e5c858e7c9f5bc0e2687938e8948373c 178 TIGRFAM TIGR00566 trpG_papA: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase 1 173 6.5E-42 T 31-10-2018 IPR006221 Anthranilate synthase/para-aminobenzoate synthase like domain KEGG: 00400+4.1.3.27|KEGG: 00405+4.1.3.27|MetaCyc: PWY-5958|MetaCyc: PWY-6660|MetaCyc: PWY-6661 AF_1602 e5c858e7c9f5bc0e2687938e8948373c 178 Gene3D G3DSA:3.40.50.880 1 177 1.1E-54 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_1602 e5c858e7c9f5bc0e2687938e8948373c 178 PRINTS PR00097 Anthranilate synthase component II signature 90 98 2.6E-31 T 31-10-2018 AF_1602 e5c858e7c9f5bc0e2687938e8948373c 178 PRINTS PR00097 Anthranilate synthase component II signature 151 164 2.6E-31 T 31-10-2018 AF_1602 e5c858e7c9f5bc0e2687938e8948373c 178 PRINTS PR00097 Anthranilate synthase component II signature 110 122 2.6E-31 T 31-10-2018 AF_1602 e5c858e7c9f5bc0e2687938e8948373c 178 PRINTS PR00097 Anthranilate synthase component II signature 44 53 2.6E-31 T 31-10-2018 AF_1602 e5c858e7c9f5bc0e2687938e8948373c 178 PRINTS PR00097 Anthranilate synthase component II signature 2 16 2.6E-31 T 31-10-2018 AF_1602 e5c858e7c9f5bc0e2687938e8948373c 178 PRINTS PR00097 Anthranilate synthase component II signature 66 77 2.6E-31 T 31-10-2018 AF_1602 e5c858e7c9f5bc0e2687938e8948373c 178 PRINTS PR00096 Glutamine amidotransferase superfamily signature 151 164 1.5E-14 T 31-10-2018 AF_1602 e5c858e7c9f5bc0e2687938e8948373c 178 PRINTS PR00096 Glutamine amidotransferase superfamily signature 44 53 1.5E-14 T 31-10-2018 AF_1602 e5c858e7c9f5bc0e2687938e8948373c 178 PRINTS PR00096 Glutamine amidotransferase superfamily signature 66 77 1.5E-14 T 31-10-2018 AF_1602 e5c858e7c9f5bc0e2687938e8948373c 178 SUPERFAMILY SSF52317 1 176 4.76E-47 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_1602 e5c858e7c9f5bc0e2687938e8948373c 178 Pfam PF00117 Glutamine amidotransferase class-I 3 172 2.5E-39 T 31-10-2018 IPR017926 Glutamine amidotransferase AF_0355 5db052d81652335867e052604d9f7ea0 69 Gene3D G3DSA:3.30.70.20 42 69 5.5E-9 T 31-10-2018 AF_0355 5db052d81652335867e052604d9f7ea0 69 Gene3D G3DSA:3.30.70.20 11 41 3.9E-8 T 31-10-2018 AF_0355 5db052d81652335867e052604d9f7ea0 69 SUPERFAMILY SSF54862 12 68 1.26E-20 T 31-10-2018 AF_0355 5db052d81652335867e052604d9f7ea0 69 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 51 62 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0355 5db052d81652335867e052604d9f7ea0 69 Pfam PF12838 4Fe-4S dicluster domain 23 65 3.1E-10 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0425 ecf5b91c3658452c355b8a037e91c2ce 77 SUPERFAMILY SSF46785 5 71 5.17E-17 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0425 ecf5b91c3658452c355b8a037e91c2ce 77 Gene3D G3DSA:1.10.10.10 5 76 9.4E-10 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0425 ecf5b91c3658452c355b8a037e91c2ce 77 Pfam PF08679 Dissimilatory sulfite reductase D (DsrD) 9 64 7.4E-10 T 31-10-2018 IPR014793 Dissimilatory sulphite reductase D AF_1891 492eb4f934e669e22dc6ffa386afe74d 139 Pfam PF07650 KH domain 14 90 2.9E-16 T 31-10-2018 IPR004044 K Homology domain, type 2 GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1891 492eb4f934e669e22dc6ffa386afe74d 139 SUPERFAMILY SSF54814 72 135 5.3E-13 T 31-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AF_1891 492eb4f934e669e22dc6ffa386afe74d 139 Hamap MF_00945_A Transcription termination/antitermination protein NusA [nusA]. 1 139 28.598 T 31-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal AF_1891 492eb4f934e669e22dc6ffa386afe74d 139 SUPERFAMILY SSF54814 13 72 1.7E-11 T 31-10-2018 IPR009019 K homology domain superfamily, prokaryotic type GO:0003723 AF_1891 492eb4f934e669e22dc6ffa386afe74d 139 TIGRFAM TIGR01952 nusA_arch: NusA family KH domain protein, archaeal 1 138 1.2E-61 T 31-10-2018 IPR010212 Probable transcription termination protein NusA, archaeal AF_1891 492eb4f934e669e22dc6ffa386afe74d 139 Gene3D G3DSA:3.30.300.20 72 139 5.4E-24 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta AF_1891 492eb4f934e669e22dc6ffa386afe74d 139 Gene3D G3DSA:3.30.300.20 1 71 8.9E-25 T 31-10-2018 IPR015946 K homology domain-like, alpha/beta AF_1891 492eb4f934e669e22dc6ffa386afe74d 139 SMART SM00322 30 97 2.8E-4 T 31-10-2018 IPR004087 K Homology domain GO:0003676 AF_1046 e427c0a7f9b45d955d1ecb1036f2863a 223 SMART SM00388 153 209 0.0051 T 31-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AF_1046 e427c0a7f9b45d955d1ecb1036f2863a 223 Gene3D G3DSA:1.10.287.130 107 207 4.8E-5 T 31-10-2018 AF_0997 ae4c6cfc1b8af4afc6ba147d82035da4 416 SUPERFAMILY SSF51338 3 412 7.48E-18 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AF_0997 ae4c6cfc1b8af4afc6ba147d82035da4 416 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 3 414 42.256 T 31-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 AF_0997 ae4c6cfc1b8af4afc6ba147d82035da4 416 Gene3D G3DSA:3.20.20.140 53 338 7.5E-125 T 31-10-2018 AF_0997 ae4c6cfc1b8af4afc6ba147d82035da4 416 Gene3D G3DSA:2.30.40.10 20 406 7.5E-125 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AF_0997 ae4c6cfc1b8af4afc6ba147d82035da4 416 SUPERFAMILY SSF51556 52 341 5.79E-96 T 31-10-2018 IPR032466 Metal-dependent hydrolase AF_0997 ae4c6cfc1b8af4afc6ba147d82035da4 416 Pfam PF01979 Amidohydrolase family 49 363 1.7E-74 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AF_1533 53b9401ec31c854bf6b64e4b7e1f1cbd 278 SUPERFAMILY SSF103481 37 138 3.79E-11 T 31-10-2018 AF_1533 53b9401ec31c854bf6b64e4b7e1f1cbd 278 Pfam PF00892 EamA-like transporter family 144 273 1.0E-17 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AF_1533 53b9401ec31c854bf6b64e4b7e1f1cbd 278 Pfam PF00892 EamA-like transporter family 4 135 4.8E-24 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AF_1533 53b9401ec31c854bf6b64e4b7e1f1cbd 278 SUPERFAMILY SSF103481 183 276 5.1E-12 T 31-10-2018 AF_1426 a6158933543b00e6f124b7a6bc22b587 246 Gene3D G3DSA:1.20.1080.10 1 246 2.0E-96 T 31-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 AF_1426 a6158933543b00e6f124b7a6bc22b587 246 ProSitePatterns PS00221 MIP family signature. 81 89 - T 31-10-2018 IPR022357 Major intrinsic protein, conserved site Reactome: R-HSA-432047 AF_1426 a6158933543b00e6f124b7a6bc22b587 246 Pfam PF00230 Major intrinsic protein 3 240 1.8E-48 T 31-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AF_1426 a6158933543b00e6f124b7a6bc22b587 246 SUPERFAMILY SSF81338 5 243 2.62E-61 T 31-10-2018 IPR023271 Aquaporin-like Reactome: R-HSA-432047 AF_1426 a6158933543b00e6f124b7a6bc22b587 246 TIGRFAM TIGR00861 MIP: MIP family channel proteins 11 240 4.4E-64 T 31-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AF_1426 a6158933543b00e6f124b7a6bc22b587 246 PRINTS PR00783 Major intrinsic protein family signature 100 119 3.8E-46 T 31-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AF_1426 a6158933543b00e6f124b7a6bc22b587 246 PRINTS PR00783 Major intrinsic protein family signature 7 26 3.8E-46 T 31-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AF_1426 a6158933543b00e6f124b7a6bc22b587 246 PRINTS PR00783 Major intrinsic protein family signature 63 87 3.8E-46 T 31-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AF_1426 a6158933543b00e6f124b7a6bc22b587 246 PRINTS PR00783 Major intrinsic protein family signature 150 168 3.8E-46 T 31-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AF_1426 a6158933543b00e6f124b7a6bc22b587 246 PRINTS PR00783 Major intrinsic protein family signature 181 203 3.8E-46 T 31-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AF_1426 a6158933543b00e6f124b7a6bc22b587 246 PRINTS PR00783 Major intrinsic protein family signature 223 243 3.8E-46 T 31-10-2018 IPR000425 Major intrinsic protein GO:0015267|GO:0016020|GO:0055085 Reactome: R-HSA-432047 AF_0622 90898d8f1e42ad22597ea12ed0088b53 433 Hamap MF_00306 Signal recognition particle 54 kDa protein [srp54]. 2 432 35.522 T 31-10-2018 IPR022941 Signal recognition particle, SRP54 subunit GO:0003924|GO:0005525|GO:0006614|GO:0048500 Reactome: R-HSA-1799339 AF_0622 90898d8f1e42ad22597ea12ed0088b53 433 Pfam PF02978 Signal peptide binding domain 315 415 1.8E-29 T 31-10-2018 IPR004125 Signal recognition particle, SRP54 subunit, M-domain GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AF_0622 90898d8f1e42ad22597ea12ed0088b53 433 Pfam PF00448 SRP54-type protein, GTPase domain 95 286 2.0E-75 T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AF_0622 90898d8f1e42ad22597ea12ed0088b53 433 SUPERFAMILY SSF47446 288 419 3.14E-37 T 31-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AF_0622 90898d8f1e42ad22597ea12ed0088b53 433 SUPERFAMILY SSF47364 4 85 2.09E-19 T 31-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 AF_0622 90898d8f1e42ad22597ea12ed0088b53 433 SMART SM00962 93 286 1.3E-99 T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AF_0622 90898d8f1e42ad22597ea12ed0088b53 433 SUPERFAMILY SSF52540 94 288 1.45E-49 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0622 90898d8f1e42ad22597ea12ed0088b53 433 ProSitePatterns PS00300 SRP54-type proteins GTP-binding domain signature. 259 272 - T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AF_0622 90898d8f1e42ad22597ea12ed0088b53 433 Gene3D G3DSA:1.10.260.30 308 425 2.1E-44 T 31-10-2018 IPR036891 Signal recognition particle, SRP54 subunit, M-domain superfamily GO:0006614|GO:0008312|GO:0048500 Reactome: R-HSA-1799339 AF_0622 90898d8f1e42ad22597ea12ed0088b53 433 SMART SM00382 92 276 4.0E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0622 90898d8f1e42ad22597ea12ed0088b53 433 Pfam PF02881 SRP54-type protein, helical bundle domain 4 79 2.1E-17 T 31-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AF_0622 90898d8f1e42ad22597ea12ed0088b53 433 Gene3D G3DSA:1.20.120.140 5 296 5.0E-109 T 31-10-2018 AF_0622 90898d8f1e42ad22597ea12ed0088b53 433 Gene3D G3DSA:3.40.50.300 86 275 5.0E-109 T 31-10-2018 AF_0622 90898d8f1e42ad22597ea12ed0088b53 433 SMART SM00963 2 83 1.4E-14 T 31-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AF_2253 b7ba3c760bc873a7cc7d787558c5bcf5 159 Gene3D G3DSA:3.40.50.300 1 159 1.3E-64 T 31-10-2018 AF_2253 b7ba3c760bc873a7cc7d787558c5bcf5 159 SUPERFAMILY SSF52540 2 116 2.31E-14 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2253 b7ba3c760bc873a7cc7d787558c5bcf5 159 TIGRFAM TIGR00176 mobB: molybdopterin-guanine dinucleotide biosynthesis protein B 2 156 2.5E-36 T 31-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 AF_2253 b7ba3c760bc873a7cc7d787558c5bcf5 159 Pfam PF03205 Molybdopterin guanine dinucleotide synthesis protein B 2 133 5.4E-35 T 31-10-2018 IPR004435 Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB) domain GO:0005525|GO:0006777 AF_0873 4d29f8e526278e3046f950b0da5141bb 457 PIRSF PIRSF000485 1 456 1.4E-179 T 31-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AF_0873 4d29f8e526278e3046f950b0da5141bb 457 TIGRFAM TIGR01134 purF: amidophosphoribosyltransferase 2 447 2.8E-171 T 31-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AF_0873 4d29f8e526278e3046f950b0da5141bb 457 SUPERFAMILY SSF53271 239 453 1.78E-72 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like AF_0873 4d29f8e526278e3046f950b0da5141bb 457 Pfam PF00156 Phosphoribosyl transferase domain 275 373 3.0E-7 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AF_0873 4d29f8e526278e3046f950b0da5141bb 457 SUPERFAMILY SSF56235 2 239 1.03E-64 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AF_0873 4d29f8e526278e3046f950b0da5141bb 457 Gene3D G3DSA:3.40.50.2020 263 427 1.4E-158 T 31-10-2018 AF_0873 4d29f8e526278e3046f950b0da5141bb 457 Pfam PF13537 Glutamine amidotransferase domain 83 202 2.7E-20 T 31-10-2018 IPR017932 Glutamine amidotransferase type 2 domain AF_0873 4d29f8e526278e3046f950b0da5141bb 457 Hamap MF_01931 Amidophosphoribosyltransferase [purF]. 1 446 48.41 T 31-10-2018 IPR005854 Amidophosphoribosyltransferase GO:0004044|GO:0009113 KEGG: 00230+2.4.2.14|KEGG: 00250+2.4.2.14|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|MetaCyc: PWY-7282|Reactome: R-HSA-73817 AF_0873 4d29f8e526278e3046f950b0da5141bb 457 Gene3D G3DSA:3.60.20.10 2 448 1.4E-158 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AF_2049 9d5ab5da6dd462e3d593c73749f5cbbf 378 SUPERFAMILY SSF52540 65 102 1.41E-5 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2049 9d5ab5da6dd462e3d593c73749f5cbbf 378 Gene3D G3DSA:3.40.50.300 64 246 1.3E-10 T 31-10-2018 AF_2049 9d5ab5da6dd462e3d593c73749f5cbbf 378 Pfam PF16575 mRNA cleavage and polyadenylation factor CLP1 P-loop 80 238 1.3E-22 T 31-10-2018 IPR032319 Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain AF_2049 9d5ab5da6dd462e3d593c73749f5cbbf 378 SUPERFAMILY SSF52540 75 271 8.62E-5 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0781 941682d6d1c00ba57bc90214dc36dba1 309 Gene3D G3DSA:3.40.50.11030 214 309 1.4E-13 T 31-10-2018 IPR038385 Threonylcarbamoyl-AMP synthase, C-terminal domain superfamily AF_0781 941682d6d1c00ba57bc90214dc36dba1 309 PIRSF PIRSF004930 2 309 8.0E-95 T 31-10-2018 IPR010923 tRNA threonylcarbamoyladenosine biosynthesis protein SUA5 AF_0781 941682d6d1c00ba57bc90214dc36dba1 309 TIGRFAM TIGR00057 TIGR00057: tRNA threonylcarbamoyl adenosine modification protein, Sua5/YciO/YrdC/YwlC family 4 200 4.5E-78 T 31-10-2018 IPR006070 YrdC-like domain GO:0003725 AF_0781 941682d6d1c00ba57bc90214dc36dba1 309 SUPERFAMILY SSF55821 5 196 1.92E-60 T 31-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AF_0781 941682d6d1c00ba57bc90214dc36dba1 309 Gene3D G3DSA:3.90.870.10 2 205 2.1E-69 T 31-10-2018 AF_0781 941682d6d1c00ba57bc90214dc36dba1 309 Pfam PF01300 Telomere recombination 18 190 8.6E-55 T 31-10-2018 IPR006070 YrdC-like domain GO:0003725 AF_0781 941682d6d1c00ba57bc90214dc36dba1 309 Pfam PF03481 Putative GTP-binding controlling metal-binding 209 302 5.8E-8 T 31-10-2018 IPR005145 Putative GTP-binding controlling metal-binding domain AF_0045 32fb6b9c774f3d9f1d793656a4705429 1213 Pfam PF00534 Glycosyl transferases group 1 218 374 2.6E-32 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 AF_0045 32fb6b9c774f3d9f1d793656a4705429 1213 Pfam PF00534 Glycosyl transferases group 1 601 769 2.9E-12 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 AF_0045 32fb6b9c774f3d9f1d793656a4705429 1213 Pfam PF00534 Glycosyl transferases group 1 1038 1182 1.1E-23 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 AF_0045 32fb6b9c774f3d9f1d793656a4705429 1213 SUPERFAMILY SSF53756 16 393 1.31E-62 T 31-10-2018 AF_0045 32fb6b9c774f3d9f1d793656a4705429 1213 SUPERFAMILY SSF53756 846 1208 5.08E-49 T 31-10-2018 AF_0045 32fb6b9c774f3d9f1d793656a4705429 1213 Gene3D G3DSA:3.40.50.2000 17 389 2.5E-46 T 31-10-2018 AF_0045 32fb6b9c774f3d9f1d793656a4705429 1213 Gene3D G3DSA:3.40.50.2000 417 784 3.5E-28 T 31-10-2018 AF_0045 32fb6b9c774f3d9f1d793656a4705429 1213 Gene3D G3DSA:3.40.50.2000 591 771 3.5E-28 T 31-10-2018 AF_0045 32fb6b9c774f3d9f1d793656a4705429 1213 Gene3D G3DSA:3.40.50.2000 196 375 2.5E-46 T 31-10-2018 AF_0045 32fb6b9c774f3d9f1d793656a4705429 1213 SUPERFAMILY SSF53756 415 791 2.83E-36 T 31-10-2018 AF_0045 32fb6b9c774f3d9f1d793656a4705429 1213 Gene3D G3DSA:3.40.50.2000 1012 1194 6.2E-29 T 31-10-2018 AF_0261 8d4548f5f2b840d243980e751dafddf6 405 Pfam PF04165 Protein of unknown function (DUF401) 17 405 1.4E-207 T 31-10-2018 IPR007294 Protein of unknown function DUF401 AF_0261 8d4548f5f2b840d243980e751dafddf6 405 TIGRFAM TIGR00529 AF0261: integral membrane protein, TIGR00529 family 17 405 9.0E-177 T 31-10-2018 IPR005253 Conserved hypothetical protein CHP00529 AF_1521 7c8ce86502a546c1a7e3c1d602d661da 199 SMART SM00506 20 163 3.3E-52 T 31-10-2018 IPR002589 Macro domain AF_1521 7c8ce86502a546c1a7e3c1d602d661da 199 Gene3D G3DSA:3.40.220.10 1 199 8.3E-63 T 31-10-2018 AF_1521 7c8ce86502a546c1a7e3c1d602d661da 199 SUPERFAMILY SSF52949 11 196 2.69E-50 T 31-10-2018 AF_1521 7c8ce86502a546c1a7e3c1d602d661da 199 Pfam PF01661 Macro domain 37 162 6.3E-31 T 31-10-2018 IPR002589 Macro domain AF_1608 6598f240ff1aec2f4a7451ead80e2832 345 Gene3D G3DSA:3.40.50.300 3 242 1.2E-77 T 31-10-2018 AF_1608 6598f240ff1aec2f4a7451ead80e2832 345 Gene3D G3DSA:2.40.50.140 276 334 2.8E-5 T 31-10-2018 AF_1608 6598f240ff1aec2f4a7451ead80e2832 345 SMART SM00382 30 214 4.1E-18 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1608 6598f240ff1aec2f4a7451ead80e2832 345 SUPERFAMILY SSF50331 240 344 7.14E-18 T 31-10-2018 IPR008995 Molybdate/tungstate binding, C-terminal AF_1608 6598f240ff1aec2f4a7451ead80e2832 345 ProSitePatterns PS00211 ABC transporters family signature. 138 152 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_1608 6598f240ff1aec2f4a7451ead80e2832 345 SUPERFAMILY SSF52540 6 248 2.79E-86 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1608 6598f240ff1aec2f4a7451ead80e2832 345 Pfam PF00005 ABC transporter 21 165 1.9E-35 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_1608 6598f240ff1aec2f4a7451ead80e2832 345 Pfam PF08402 TOBE domain 273 343 3.2E-13 T 31-10-2018 IPR013611 Transport-associated OB, type 2 GO:0005524|GO:0022857|GO:0043190|GO:0055085 AF_1904 2c12bceb92bac08eaab611267abf2caf 152 Gene3D G3DSA:3.30.1390.20 3 140 6.7E-55 T 31-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily AF_1904 2c12bceb92bac08eaab611267abf2caf 152 Hamap MF_01371_A 50S ribosomal protein L30 [rpmD]. 1 152 82.095 T 31-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 AF_1904 2c12bceb92bac08eaab611267abf2caf 152 Gene3D G3DSA:1.10.15.30 58 113 6.7E-55 T 31-10-2018 IPR023106 Ribosomal protein L30, central domain, archaeal type AF_1904 2c12bceb92bac08eaab611267abf2caf 152 SUPERFAMILY SSF55129 1 152 4.32E-49 T 31-10-2018 IPR036919 Ribosomal protein L30, ferredoxin-like fold domain superfamily AF_1904 2c12bceb92bac08eaab611267abf2caf 152 Pfam PF00327 Ribosomal protein L30p/L7e 3 52 6.4E-18 T 31-10-2018 IPR016082 Ribosomal protein L30, ferredoxin-like fold domain AF_1904 2c12bceb92bac08eaab611267abf2caf 152 ProSitePatterns PS00634 Ribosomal protein L30 signature. 20 52 - T 31-10-2018 IPR018038 Ribosomal protein L30, conserved site AF_1904 2c12bceb92bac08eaab611267abf2caf 152 TIGRFAM TIGR01309 uL30_arch: ribosomal protein uL30 2 152 1.7E-70 T 31-10-2018 IPR005997 Ribosomal protein L30, archaeal GO:0003735|GO:0006412|GO:0015934 AF_2097 b6a807ce116c8021122a3c695164398b 395 Hamap MF_01074 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide nickel insertion protein [larC]. 1 387 34.414 T 31-10-2018 IPR002822 Nickel insertion protein AF_2097 b6a807ce116c8021122a3c695164398b 395 Pfam PF01969 Protein of unknown function DUF111 5 377 1.4E-108 T 31-10-2018 IPR002822 Nickel insertion protein AF_2097 b6a807ce116c8021122a3c695164398b 395 Gene3D G3DSA:3.30.70.1380 231 324 1.2E-27 T 31-10-2018 AF_2097 b6a807ce116c8021122a3c695164398b 395 TIGRFAM TIGR00299 TIGR00299: TIGR00299 family protein 3 377 3.0E-171 T 31-10-2018 IPR002822 Nickel insertion protein AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 TIGRFAM TIGR01511 ATPase-IB1_Cu: copper-translocating P-type ATPase 108 690 1.5E-205 T 31-10-2018 AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 SUPERFAMILY SSF81665 125 656 3.66E-11 T 31-10-2018 IPR023298 P-type ATPase, transmembrane domain superfamily Reactome: R-HSA-936837 AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 TIGRFAM TIGR01512 ATPase-IB2_Cd: cadmium-translocating P-type ATPase 155 687 2.2E-122 T 31-10-2018 AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 Gene3D G3DSA:2.70.150.20 180 292 2.6E-40 T 31-10-2018 AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 Gene3D G3DSA:3.40.1110.10 398 514 4.0E-107 T 31-10-2018 IPR023299 P-type ATPase, cytoplasmic domain N GO:0000166 Reactome: R-HSA-936837 AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 Pfam PF00702 haloacid dehalogenase-like hydrolase 384 595 3.8E-47 T 31-10-2018 AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 TIGRFAM TIGR01525 ATPase-IB_hvy: heavy metal translocating P-type ATPase 126 688 1.1E-199 T 31-10-2018 IPR027256 P-type ATPase, subfamily IB GO:0006812|GO:0016021|GO:0019829 Reactome: R-HSA-936837 AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 Gene3D G3DSA:3.40.50.1000 381 631 4.0E-107 T 31-10-2018 IPR023214 HAD superfamily AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 TIGRFAM TIGR01494 ATPase_P-type: HAD ATPase, P-type, family IC 163 663 3.2E-101 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 Pfam PF00122 E1-E2 ATPase 188 366 2.3E-54 T 31-10-2018 AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 SUPERFAMILY SSF81653 190 287 4.18E-30 T 31-10-2018 IPR008250 P-type ATPase, A domain superfamily Reactome: R-HSA-936837 AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 SUPERFAMILY SSF56784 386 686 2.64E-63 T 31-10-2018 IPR036412 HAD-like superfamily AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 ProSitePatterns PS00154 E1-E2 ATPases phosphorylation site. 389 395 - T 31-10-2018 IPR018303 P-type ATPase, phosphorylation site Reactome: R-HSA-936837 AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 554 570 2.0E-10 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 581 597 2.0E-10 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 PRINTS PR00120 H+-transporting ATPase (proton pump) signature 612 637 2.0E-10 T 31-10-2018 IPR001757 P-type ATPase GO:0016021 Reactome: R-HSA-936837 AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 387 401 3.2E-30 T 31-10-2018 AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 604 616 3.2E-30 T 31-10-2018 AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 237 251 3.2E-30 T 31-10-2018 AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 507 518 3.2E-30 T 31-10-2018 AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 529 539 3.2E-30 T 31-10-2018 AF_0152 da9f9f79f0345aa0913c0d1a4d7319d1 690 PRINTS PR00119 P-type cation-transporting ATPase superfamily signature 581 600 3.2E-30 T 31-10-2018 AF_1379 db901cf83983d26ad76f7c2a413649b9 231 SUPERFAMILY SSF81342 10 217 2.9E-22 T 31-10-2018 IPR016174 Di-haem cytochrome, transmembrane GO:0016020|GO:0022904 Reactome: R-HSA-611105 AF_1379 db901cf83983d26ad76f7c2a413649b9 231 Gene3D G3DSA:1.20.950.20 7 221 1.5E-13 T 31-10-2018 AF_1379 db901cf83983d26ad76f7c2a413649b9 231 Pfam PF01292 Prokaryotic cytochrome b561 13 211 1.1E-24 T 31-10-2018 IPR011577 Cytochrome b561, bacterial/Ni-hydrogenase GO:0009055|GO:0016021 AF_0890 da086ee43576ff3977898a47dbe3e77c 397 Gene3D G3DSA:3.40.50.2300 65 318 1.5E-144 T 31-10-2018 AF_0890 da086ee43576ff3977898a47dbe3e77c 397 Gene3D G3DSA:3.40.50.2300 165 384 1.5E-144 T 31-10-2018 AF_0890 da086ee43576ff3977898a47dbe3e77c 397 Pfam PF02608 ABC transporter substrate-binding protein PnrA-like 63 362 1.0E-97 T 31-10-2018 IPR003760 ABC transporter substrate-binding protein PnrA-like GO:0005886 AF_0623 64e00fc5920fec6f86328161f27b6bb2 556 SUPERFAMILY SSF56091 221 420 9.59E-55 T 31-10-2018 AF_0623 64e00fc5920fec6f86328161f27b6bb2 556 TIGRFAM TIGR00574 dnl1: DNA ligase I, ATP-dependent (dnl1) 59 548 2.5E-142 T 31-10-2018 IPR000977 DNA ligase, ATP-dependent GO:0003910|GO:0005524|GO:0006281|GO:0006310|GO:0071897 AF_0623 64e00fc5920fec6f86328161f27b6bb2 556 Gene3D G3DSA:3.30.470.30 223 419 4.3E-77 T 31-10-2018 AF_0623 64e00fc5920fec6f86328161f27b6bb2 556 Gene3D G3DSA:2.40.50.140 420 556 1.1E-51 T 31-10-2018 AF_0623 64e00fc5920fec6f86328161f27b6bb2 556 Pfam PF04679 ATP dependent DNA ligase C terminal region 440 532 8.7E-21 T 31-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 AF_0623 64e00fc5920fec6f86328161f27b6bb2 556 Hamap MF_00407 DNA ligase [lig]. 2 548 33.328 T 31-10-2018 IPR022865 DNA ligase, ATP-dependent, bacterial/archaeal GO:0003910 AF_0623 64e00fc5920fec6f86328161f27b6bb2 556 SUPERFAMILY SSF50249 423 550 8.4E-39 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0623 64e00fc5920fec6f86328161f27b6bb2 556 ProSitePatterns PS00333 ATP-dependent DNA ligase signature 2. 396 420 - T 31-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 AF_0623 64e00fc5920fec6f86328161f27b6bb2 556 ProSitePatterns PS00697 ATP-dependent DNA ligase AMP-binding site. 248 256 - T 31-10-2018 IPR016059 DNA ligase, ATP-dependent, conserved site GO:0003909|GO:0051103 AF_0623 64e00fc5920fec6f86328161f27b6bb2 556 SUPERFAMILY SSF117018 2 243 1.22E-68 T 31-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 AF_0623 64e00fc5920fec6f86328161f27b6bb2 556 Pfam PF01068 ATP dependent DNA ligase domain 227 420 5.4E-63 T 31-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 AF_0623 64e00fc5920fec6f86328161f27b6bb2 556 Gene3D G3DSA:1.10.3260.10 1 222 1.1E-80 T 31-10-2018 IPR036599 DNA ligase, ATP-dependent, N-terminal domain superfamily GO:0003677|GO:0003910|GO:0006281|GO:0006310 AF_0623 64e00fc5920fec6f86328161f27b6bb2 556 Pfam PF04675 DNA ligase N terminus 4 178 1.4E-38 T 31-10-2018 IPR012308 DNA ligase, ATP-dependent, N-terminal GO:0003677|GO:0003910|GO:0006281|GO:0006310 AF_1390 cce6ae58934fb9e909530ae0a851a64d 274 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 243 264 1.1E-7 T 31-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AF_1390 cce6ae58934fb9e909530ae0a851a64d 274 Gene3D G3DSA:3.40.50.300 15 265 1.7E-65 T 31-10-2018 AF_1390 cce6ae58934fb9e909530ae0a851a64d 274 Pfam PF00005 ABC transporter 36 194 5.0E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_1390 cce6ae58934fb9e909530ae0a851a64d 274 SUPERFAMILY SSF52540 20 265 9.99E-61 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1390 cce6ae58934fb9e909530ae0a851a64d 274 ProSitePatterns PS00211 ABC transporters family signature. 166 180 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_1390 cce6ae58934fb9e909530ae0a851a64d 274 SMART SM00382 45 242 1.1E-6 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1635 28f3c6c0b7b85bcf0c3b9b10bea501cc 132 Gene3D G3DSA:3.20.20.70 18 131 1.8E-9 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1635 28f3c6c0b7b85bcf0c3b9b10bea501cc 132 SUPERFAMILY SSF102114 6 129 3.79E-17 T 31-10-2018 AF_1635 28f3c6c0b7b85bcf0c3b9b10bea501cc 132 Pfam PF04055 Radical SAM superfamily 22 129 2.5E-12 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_0674 075db5993c4efc7445958fd65515b734 125 PIRSF PIRSF037373 1 123 4.5E-50 T 31-10-2018 IPR017185 Uncharacterised conserved protein UCP037373, transcriptional regulator, AF0674 AF_0674 075db5993c4efc7445958fd65515b734 125 SUPERFAMILY SSF46785 17 115 1.62E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0674 075db5993c4efc7445958fd65515b734 125 Gene3D G3DSA:1.10.10.10 9 120 2.0E-13 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1783 afd09fefbfe8ece01a242a626333174b 244 ProSitePatterns PS01131 Ribosomal RNA adenine dimethylases signature. 33 59 - T 31-10-2018 IPR020596 Ribosomal RNA adenine methylase transferase, conserved site GO:0000154|GO:0000179|GO:0008649 AF_1783 afd09fefbfe8ece01a242a626333174b 244 SMART SM00650 17 178 4.2E-76 T 31-10-2018 IPR020598 Ribosomal RNA adenine methylase transferase, N-terminal GO:0000154|GO:0000179|GO:0008649 AF_1783 afd09fefbfe8ece01a242a626333174b 244 SUPERFAMILY SSF53335 2 240 1.07E-60 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_1783 afd09fefbfe8ece01a242a626333174b 244 Pfam PF00398 Ribosomal RNA adenine dimethylase 2 208 1.5E-46 T 31-10-2018 IPR001737 Ribosomal RNA adenine methyltransferase KsgA/Erm AF_1783 afd09fefbfe8ece01a242a626333174b 244 TIGRFAM TIGR00755 ksgA: ribosomal RNA small subunit methyltransferase A 2 241 1.1E-74 T 31-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 AF_1783 afd09fefbfe8ece01a242a626333174b 244 Hamap MF_00607 Ribosomal RNA small subunit methyltransferase A [rsmA]. 1 243 44.726 T 31-10-2018 IPR011530 Ribosomal RNA adenine dimethylase GO:0000179|GO:0006364 AF_1783 afd09fefbfe8ece01a242a626333174b 244 Gene3D G3DSA:3.40.50.150 3 179 3.4E-56 T 31-10-2018 AF_2409 09bc36b72b454f1962978b04a5fdf2ca 234 Pfam PF13484 4Fe-4S double cluster binding domain 161 225 3.8E-8 T 31-10-2018 AF_2409 09bc36b72b454f1962978b04a5fdf2ca 234 SUPERFAMILY SSF54862 156 225 8.97E-8 T 31-10-2018 AF_0004 b41f8bd8b583a72e7c665632b2eac9ac 586 Pfam PF00005 ABC transporter 357 478 6.4E-17 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0004 b41f8bd8b583a72e7c665632b2eac9ac 586 SUPERFAMILY SSF52540 333 525 1.33E-35 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0004 b41f8bd8b583a72e7c665632b2eac9ac 586 ProSitePatterns PS00211 ABC transporters family signature. 209 223 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_0004 b41f8bd8b583a72e7c665632b2eac9ac 586 ProSitePatterns PS00211 ABC transporters family signature. 450 464 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_0004 b41f8bd8b583a72e7c665632b2eac9ac 586 Gene3D G3DSA:3.40.50.300 327 585 3.4E-53 T 31-10-2018 AF_0004 b41f8bd8b583a72e7c665632b2eac9ac 586 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 49 60 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0004 b41f8bd8b583a72e7c665632b2eac9ac 586 SUPERFAMILY SSF52540 87 279 4.23E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0004 b41f8bd8b583a72e7c665632b2eac9ac 586 Pfam PF00037 4Fe-4S binding domain 43 64 3.6E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0004 b41f8bd8b583a72e7c665632b2eac9ac 586 SMART SM00382 96 285 2.5E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0004 b41f8bd8b583a72e7c665632b2eac9ac 586 SMART SM00382 360 528 1.8E-5 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0004 b41f8bd8b583a72e7c665632b2eac9ac 586 Gene3D G3DSA:3.40.50.300 1 323 2.8E-78 T 31-10-2018 AF_0004 b41f8bd8b583a72e7c665632b2eac9ac 586 PRINTS PR01868 ABC transporter family E signature 101 126 4.1E-55 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 AF_0004 b41f8bd8b583a72e7c665632b2eac9ac 586 PRINTS PR01868 ABC transporter family E signature 73 93 4.1E-55 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 AF_0004 b41f8bd8b583a72e7c665632b2eac9ac 586 PRINTS PR01868 ABC transporter family E signature 132 148 4.1E-55 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 AF_0004 b41f8bd8b583a72e7c665632b2eac9ac 586 PRINTS PR01868 ABC transporter family E signature 148 174 4.1E-55 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 AF_0004 b41f8bd8b583a72e7c665632b2eac9ac 586 PRINTS PR01868 ABC transporter family E signature 21 36 4.1E-55 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 AF_0004 b41f8bd8b583a72e7c665632b2eac9ac 586 PRINTS PR01868 ABC transporter family E signature 46 70 4.1E-55 T 31-10-2018 IPR013283 RLI1 Reactome: R-HSA-909733 AF_0004 b41f8bd8b583a72e7c665632b2eac9ac 586 Pfam PF04068 Possible Fer4-like domain in RNase L inhibitor, RLI 4 34 9.0E-13 T 31-10-2018 IPR007209 RNase L inhibitor RLI, possible metal-binding domain AF_0004 b41f8bd8b583a72e7c665632b2eac9ac 586 Pfam PF00005 ABC transporter 96 237 1.2E-17 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0004 b41f8bd8b583a72e7c665632b2eac9ac 586 SUPERFAMILY SSF54862 6 123 1.41E-20 T 31-10-2018 AF_2117 730faf3b07c0e3526f826f30f28989bc 295 SUPERFAMILY SSF48150 116 285 6.6E-36 T 31-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AF_2117 730faf3b07c0e3526f826f30f28989bc 295 Gene3D G3DSA:1.10.340.30 114 233 2.6E-34 T 31-10-2018 AF_2117 730faf3b07c0e3526f826f30f28989bc 295 SMART SM00478 127 283 1.6E-44 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AF_2117 730faf3b07c0e3526f826f30f28989bc 295 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 124 270 6.7E-20 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AF_2117 730faf3b07c0e3526f826f30f28989bc 295 Gene3D G3DSA:1.10.1670.10 234 295 6.0E-37 T 31-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AF_2117 730faf3b07c0e3526f826f30f28989bc 295 Gene3D G3DSA:3.30.310.20 1 113 2.3E-62 T 31-10-2018 IPR037046 DNA-3-methyladenine glycosylase AlkA, N-terminal domain superfamily AF_0519 d8c830f49f6b4767c588599fc35132ea 149 PIRSF PIRSF022062 1 146 5.8E-66 T 31-10-2018 IPR016799 Uncharacterised conserved protein UCP022062 AF_0519 d8c830f49f6b4767c588599fc35132ea 149 Pfam PF08617 Kinase binding protein CGI-121 18 115 1.6E-10 T 31-10-2018 IPR013926 CGI121/TPRKB Reactome: R-HSA-6782315 AF_0519 d8c830f49f6b4767c588599fc35132ea 149 SUPERFAMILY SSF143870 20 120 1.27E-21 T 31-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 AF_0519 d8c830f49f6b4767c588599fc35132ea 149 Gene3D G3DSA:3.30.2380.10 3 126 3.2E-19 T 31-10-2018 IPR036504 CGI121/TPRKB superfamily Reactome: R-HSA-6782315 AF_2012 2b8e05c6883391c210ef4db591a5dd23 137 SUPERFAMILY SSF88723 7 134 2.47E-19 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_2012 2b8e05c6883391c210ef4db591a5dd23 137 SMART SM00670 5 128 1.5E-19 T 31-10-2018 IPR002716 PIN domain AF_2012 2b8e05c6883391c210ef4db591a5dd23 137 Gene3D G3DSA:3.40.50.1010 6 135 1.1E-15 T 31-10-2018 AF_2012 2b8e05c6883391c210ef4db591a5dd23 137 Pfam PF01850 PIN domain 8 131 4.7E-22 T 31-10-2018 IPR002716 PIN domain AF_2260 d023866d888b1abbe13acb923c9da48f 196 Gene3D G3DSA:1.20.58.2140 1 196 1.7E-76 T 31-10-2018 AF_2260 d023866d888b1abbe13acb923c9da48f 196 SUPERFAMILY SSF74784 4 179 2.35E-25 T 31-10-2018 IPR036081 Translin superfamily GO:0043565 Reactome: R-HSA-426486 AF_2260 d023866d888b1abbe13acb923c9da48f 196 Pfam PF01997 Translin family 17 175 1.4E-9 T 31-10-2018 IPR002848 Translin family GO:0043565 Reactome: R-HSA-426486 AF_2182 797db6229adf6d7a7dc9e13891610592 92 Gene3D G3DSA:2.20.28.10 1 92 6.6E-24 T 31-10-2018 AF_2182 797db6229adf6d7a7dc9e13891610592 92 SUPERFAMILY SSF46785 5 91 8.98E-25 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1366 16f5a7abba9202588c88ce6c4fb29d48 740 Gene3D G3DSA:3.30.110.120 240 353 5.3E-125 T 31-10-2018 AF_1366 16f5a7abba9202588c88ce6c4fb29d48 740 SUPERFAMILY SSF55821 169 375 3.97E-40 T 31-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AF_1366 16f5a7abba9202588c88ce6c4fb29d48 740 SUPERFAMILY SSF54975 3 84 1.88E-20 T 31-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AF_1366 16f5a7abba9202588c88ce6c4fb29d48 740 PIRSF PIRSF006256 1 740 1.7E-254 T 31-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 AF_1366 16f5a7abba9202588c88ce6c4fb29d48 740 ProSitePatterns PS00150 Acylphosphatase signature 1. 6 16 - T 31-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AF_1366 16f5a7abba9202588c88ce6c4fb29d48 740 TIGRFAM TIGR00143 hypF: carbamoyltransferase HypF 4 735 0.0 T 31-10-2018 IPR004421 Carbamoyltransferase, HypF-type GO:0016743|GO:0046872|GO:0046944 AF_1366 16f5a7abba9202588c88ce6c4fb29d48 740 Gene3D G3DSA:3.90.870.50 4 344 5.3E-125 T 31-10-2018 AF_1366 16f5a7abba9202588c88ce6c4fb29d48 740 SUPERFAMILY SSF53067 400 721 8.42E-6 T 31-10-2018 AF_1366 16f5a7abba9202588c88ce6c4fb29d48 740 Pfam PF01300 Telomere recombination 198 365 3.5E-44 T 31-10-2018 IPR006070 YrdC-like domain GO:0003725 AF_1366 16f5a7abba9202588c88ce6c4fb29d48 740 Gene3D G3DSA:3.30.420.360 365 733 9.8E-87 T 31-10-2018 AF_1366 16f5a7abba9202588c88ce6c4fb29d48 740 Gene3D G3DSA:3.30.420.350 469 721 9.8E-87 T 31-10-2018 AF_1366 16f5a7abba9202588c88ce6c4fb29d48 740 Pfam PF07503 HypF finger 101 133 1.8E-15 T 31-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 AF_1366 16f5a7abba9202588c88ce6c4fb29d48 740 Pfam PF07503 HypF finger 151 183 7.5E-15 T 31-10-2018 IPR011125 Zinc finger, HypF-type GO:0008270 AF_1366 16f5a7abba9202588c88ce6c4fb29d48 740 Pfam PF00708 Acylphosphatase 3 83 2.0E-19 T 31-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AF_0106 1f05d88fadd6d8af9595cf0c9b15c4ed 299 Pfam PF02729 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain 3 144 8.7E-54 T 31-10-2018 IPR006132 Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding GO:0006520|GO:0016743 AF_0106 1f05d88fadd6d8af9595cf0c9b15c4ed 299 Gene3D G3DSA:3.40.50.1370 132 285 1.7E-121 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AF_0106 1f05d88fadd6d8af9595cf0c9b15c4ed 299 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 253 262 8.2E-23 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AF_0106 1f05d88fadd6d8af9595cf0c9b15c4ed 299 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 132 143 8.2E-23 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AF_0106 1f05d88fadd6d8af9595cf0c9b15c4ed 299 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 263 286 8.2E-23 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AF_0106 1f05d88fadd6d8af9595cf0c9b15c4ed 299 PRINTS PR00100 Aspartate/ornithine carbamoyltransferase superfamily signature 48 67 8.2E-23 T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AF_0106 1f05d88fadd6d8af9595cf0c9b15c4ed 299 PRINTS PR00101 Aspartate carbamoyltransferase signature 38 60 7.4E-39 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AF_0106 1f05d88fadd6d8af9595cf0c9b15c4ed 299 PRINTS PR00101 Aspartate carbamoyltransferase signature 218 227 7.4E-39 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AF_0106 1f05d88fadd6d8af9595cf0c9b15c4ed 299 PRINTS PR00101 Aspartate carbamoyltransferase signature 257 262 7.4E-39 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AF_0106 1f05d88fadd6d8af9595cf0c9b15c4ed 299 PRINTS PR00101 Aspartate carbamoyltransferase signature 77 86 7.4E-39 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AF_0106 1f05d88fadd6d8af9595cf0c9b15c4ed 299 PRINTS PR00101 Aspartate carbamoyltransferase signature 279 293 7.4E-39 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AF_0106 1f05d88fadd6d8af9595cf0c9b15c4ed 299 PRINTS PR00101 Aspartate carbamoyltransferase signature 131 148 7.4E-39 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AF_0106 1f05d88fadd6d8af9595cf0c9b15c4ed 299 SUPERFAMILY SSF53671 2 297 3.8E-101 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AF_0106 1f05d88fadd6d8af9595cf0c9b15c4ed 299 Gene3D G3DSA:3.40.50.1370 4 294 1.7E-121 T 31-10-2018 IPR036901 Aspartate/ornithine carbamoyltransferase superfamily GO:0006520|GO:0016597|GO:0016743 AF_0106 1f05d88fadd6d8af9595cf0c9b15c4ed 299 Pfam PF00185 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain 151 295 1.4E-30 T 31-10-2018 IPR006131 Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain GO:0006520|GO:0016597|GO:0016743 AF_0106 1f05d88fadd6d8af9595cf0c9b15c4ed 299 Hamap MF_00001 Aspartate carbamoyltransferase [pyrB]. 2 299 39.423 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AF_0106 1f05d88fadd6d8af9595cf0c9b15c4ed 299 TIGRFAM TIGR00670 asp_carb_tr: aspartate carbamoyltransferase 3 298 3.1E-137 T 31-10-2018 IPR002082 Aspartate carbamoyltransferase GO:0004070|GO:0006207 KEGG: 00240+2.1.3.2|KEGG: 00250+2.1.3.2|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AF_0106 1f05d88fadd6d8af9595cf0c9b15c4ed 299 ProSitePatterns PS00097 Aspartate and ornithine carbamoyltransferases signature. 48 55 - T 31-10-2018 IPR006130 Aspartate/ornithine carbamoyltransferase GO:0006520|GO:0016597|GO:0016743 AF_1177 179b7ef4cb8af1b00bd4856b0c1ac8ab 312 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 181 277 2.2E-22 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_1177 179b7ef4cb8af1b00bd4856b0c1ac8ab 312 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 178 3.0E-49 T 31-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_1177 179b7ef4cb8af1b00bd4856b0c1ac8ab 312 SUPERFAMILY SSF51735 5 178 4.47E-42 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1177 179b7ef4cb8af1b00bd4856b0c1ac8ab 312 Gene3D G3DSA:3.40.50.720 1 181 9.9E-51 T 31-10-2018 AF_1177 179b7ef4cb8af1b00bd4856b0c1ac8ab 312 Gene3D G3DSA:1.10.1040.10 182 298 1.0E-21 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AF_1177 179b7ef4cb8af1b00bd4856b0c1ac8ab 312 SUPERFAMILY SSF48179 181 284 3.4E-20 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_1177 179b7ef4cb8af1b00bd4856b0c1ac8ab 312 PIRSF PIRSF000105 1 300 4.1E-95 T 31-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 AF_2399 643eec8a499a928bf0911a5572a97897 224 Pfam PF00588 SpoU rRNA Methylase family 78 217 5.2E-37 T 31-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AF_2399 643eec8a499a928bf0911a5572a97897 224 SUPERFAMILY SSF75217 71 223 1.83E-40 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases AF_2399 643eec8a499a928bf0911a5572a97897 224 Gene3D G3DSA:3.40.1280.10 60 224 7.0E-47 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AF_2399 643eec8a499a928bf0911a5572a97897 224 TIGRFAM TIGR00186 rRNA_methyl_3: RNA methyltransferase, TrmH family, group 3 3 223 6.9E-73 T 31-10-2018 IPR004441 RNA methyltransferase TrmH family GO:0006396|GO:0008173 Reactome: R-HSA-6793080 AF_0680 6c37794013e282419bb2681260ef9126 242 SUPERFAMILY SSF52540 4 237 2.92E-84 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0680 6c37794013e282419bb2681260ef9126 242 Pfam PF00005 ABC transporter 19 167 4.2E-39 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0680 6c37794013e282419bb2681260ef9126 242 SMART SM00382 28 215 7.9E-19 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0680 6c37794013e282419bb2681260ef9126 242 PIRSF PIRSF039085 1 242 6.3E-121 T 31-10-2018 IPR030679 ABC-type amino acid transport system, ATPase component, HisP-type GO:0003333|GO:0015424 AF_0680 6c37794013e282419bb2681260ef9126 242 Gene3D G3DSA:3.40.50.300 4 242 1.5E-85 T 31-10-2018 AF_0680 6c37794013e282419bb2681260ef9126 242 ProSitePatterns PS00211 ABC transporters family signature. 139 153 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_1448 c0667bb2826ab9a95c4b64aa4f0d4882 187 Gene3D G3DSA:1.10.10.10 1 47 8.1E-14 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1448 c0667bb2826ab9a95c4b64aa4f0d4882 187 Pfam PF13412 Winged helix-turn-helix DNA-binding 1 43 1.6E-12 T 31-10-2018 AF_1448 c0667bb2826ab9a95c4b64aa4f0d4882 187 Gene3D G3DSA:3.30.70.920 52 146 1.7E-8 T 31-10-2018 AF_1448 c0667bb2826ab9a95c4b64aa4f0d4882 187 SUPERFAMILY SSF46785 1 46 1.87E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1448 c0667bb2826ab9a95c4b64aa4f0d4882 187 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 6.2E-8 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_1448 c0667bb2826ab9a95c4b64aa4f0d4882 187 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 6.2E-8 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_1448 c0667bb2826ab9a95c4b64aa4f0d4882 187 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 6.2E-8 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_1448 c0667bb2826ab9a95c4b64aa4f0d4882 187 SMART SM00344 1 105 7.8E-35 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AF_1448 c0667bb2826ab9a95c4b64aa4f0d4882 187 Pfam PF01037 Lrp/AsnC ligand binding domain 66 137 5.0E-11 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AF_1448 c0667bb2826ab9a95c4b64aa4f0d4882 187 SUPERFAMILY SSF54909 60 135 5.9E-8 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel AF_0020 e01e4cef9a98a9e6ff42eae2c2e73ea8 420 Gene3D G3DSA:3.40.50.10540 11 412 5.5E-104 T 31-10-2018 IPR023606 CoA-transferase family III domain superfamily AF_0020 e01e4cef9a98a9e6ff42eae2c2e73ea8 420 SUPERFAMILY SSF89796 6 418 1.44E-100 T 31-10-2018 IPR023606 CoA-transferase family III domain superfamily AF_0020 e01e4cef9a98a9e6ff42eae2c2e73ea8 420 Pfam PF02515 CoA-transferase family III 12 394 1.3E-110 T 31-10-2018 IPR003673 CoA-transferase family III GO:0003824 AF_0020 e01e4cef9a98a9e6ff42eae2c2e73ea8 420 Gene3D G3DSA:3.30.1540.10 241 345 5.5E-104 T 31-10-2018 AF_1050 0b78e180c8f05d0ea4ea1c2571dd0f02 244 Pfam PF06745 KaiC 22 238 1.1E-28 T 31-10-2018 IPR014774 KaiC-like domain AF_1050 0b78e180c8f05d0ea4ea1c2571dd0f02 244 Gene3D G3DSA:3.40.50.300 12 241 1.7E-53 T 31-10-2018 AF_1050 0b78e180c8f05d0ea4ea1c2571dd0f02 244 SUPERFAMILY SSF52540 12 236 9.03E-35 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2413 f2febc86fa72911779a2c76572966e10 375 SUPERFAMILY SSF102114 4 348 1.01E-70 T 31-10-2018 AF_2413 f2febc86fa72911779a2c76572966e10 375 SMART SM00729 5 205 2.1E-7 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AF_2413 f2febc86fa72911779a2c76572966e10 375 Pfam PF13353 4Fe-4S single cluster domain 12 125 3.4E-9 T 31-10-2018 AF_2413 f2febc86fa72911779a2c76572966e10 375 Pfam PF13186 Iron-sulfur cluster-binding domain 284 341 1.5E-5 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain AF_2413 f2febc86fa72911779a2c76572966e10 375 Pfam PF04055 Radical SAM superfamily 11 168 2.0E-24 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_2413 f2febc86fa72911779a2c76572966e10 375 PIRSF PIRSF037420 1 375 6.5E-135 T 31-10-2018 IPR017200 Coenzyme PQQ synthesis protein E AF_2413 f2febc86fa72911779a2c76572966e10 375 TIGRFAM TIGR04053 sam_11: radical SAM protein, BA_1875 family 2 371 8.8E-141 T 31-10-2018 IPR027634 Radical SAM protein, BA_1875 family AF_2413 f2febc86fa72911779a2c76572966e10 375 Gene3D G3DSA:3.20.20.70 6 322 1.3E-47 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0867 1950c2b1bf3cf20e0319f9df1821c75b 328 SUPERFAMILY SSF46548 24 102 2.79E-10 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_0867 1950c2b1bf3cf20e0319f9df1821c75b 328 Pfam PF13183 4Fe-4S dicluster domain 35 95 1.5E-6 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0867 1950c2b1bf3cf20e0319f9df1821c75b 328 Pfam PF02754 Cysteine-rich domain 233 316 4.2E-10 T 31-10-2018 IPR004017 Cysteine-rich domain AF_0867 1950c2b1bf3cf20e0319f9df1821c75b 328 Pfam PF02754 Cysteine-rich domain 134 210 4.0E-5 T 31-10-2018 IPR004017 Cysteine-rich domain AF_0198 6aef2bc7c09e8d43e8e7de46a2c35984 146 SUPERFAMILY SSF54637 2 145 3.03E-46 T 31-10-2018 IPR029069 HotDog domain superfamily AF_0198 6aef2bc7c09e8d43e8e7de46a2c35984 146 Pfam PF01575 MaoC like domain 11 123 1.8E-37 T 31-10-2018 IPR002539 MaoC-like dehydratase domain AF_0198 6aef2bc7c09e8d43e8e7de46a2c35984 146 Gene3D G3DSA:3.10.129.10 1 145 1.5E-51 T 31-10-2018 AF_0557 3b97991276f56f2f1a673964976c769b 380 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 291 1.9E-23 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AF_0557 3b97991276f56f2f1a673964976c769b 380 SUPERFAMILY SSF51905 195 362 1.52E-11 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0557 3b97991276f56f2f1a673964976c769b 380 SUPERFAMILY SSF51905 118 250 5.5E-34 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0557 3b97991276f56f2f1a673964976c769b 380 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 7.2E-5 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AF_0557 3b97991276f56f2f1a673964976c769b 380 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 103 111 7.2E-5 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AF_0557 3b97991276f56f2f1a673964976c769b 380 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 279 297 7.2E-5 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AF_0557 3b97991276f56f2f1a673964976c769b 380 Gene3D G3DSA:3.50.50.100 1 379 5.6E-95 T 31-10-2018 AF_0557 3b97991276f56f2f1a673964976c769b 380 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 5.2E-5 T 31-10-2018 AF_0557 3b97991276f56f2f1a673964976c769b 380 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 102 120 5.2E-5 T 31-10-2018 AF_0557 3b97991276f56f2f1a673964976c769b 380 SUPERFAMILY SSF51905 1 151 3.42E-24 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1331 3bf05ef93ab916ae8946da8774c14238 330 SUPERFAMILY SSF54197 21 168 8.29E-14 T 31-10-2018 IPR036265 HIT-like superfamily AF_1331 3bf05ef93ab916ae8946da8774c14238 330 Gene3D G3DSA:3.30.428.10 137 327 5.6E-15 T 31-10-2018 IPR036265 HIT-like superfamily AF_1561 961cfd5ac6eba93233fa6efba50da669 285 Pfam PF01925 Sulfite exporter TauE/SafE 15 275 8.2E-36 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AF_0197 a3530546ce6e051403a52669c6602972 662 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 47 103 4.3E-13 T 31-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 AF_0197 a3530546ce6e051403a52669c6602972 662 Pfam PF00501 AMP-binding enzyme 111 533 1.1E-49 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_0197 a3530546ce6e051403a52669c6602972 662 Gene3D G3DSA:3.40.50.12780 67 527 4.8E-59 T 31-10-2018 AF_0197 a3530546ce6e051403a52669c6602972 662 ProSitePatterns PS00455 Putative AMP-binding domain signature. 276 287 - T 31-10-2018 IPR020845 AMP-binding, conserved site AF_0197 a3530546ce6e051403a52669c6602972 662 SUPERFAMILY SSF56801 33 628 6.41E-118 T 31-10-2018 AF_0197 a3530546ce6e051403a52669c6602972 662 Gene3D G3DSA:3.30.300.30 530 649 1.5E-7 T 31-10-2018 AF_0197 a3530546ce6e051403a52669c6602972 662 TIGRFAM TIGR01217 ac_ac_CoA_syn: acetoacetate-CoA ligase 3 645 6.6E-217 T 31-10-2018 IPR005914 Acetoacetyl-CoA synthase GO:0006629|GO:0030729 KEGG: 00280+6.2.1.16|KEGG: 00650+6.2.1.16|Reactome: R-HSA-77111 AF_2434 cd93e67bf2a921f4f508598667d3daf2 92 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 5 92 16.035 T 31-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 AF_2434 cd93e67bf2a921f4f508598667d3daf2 92 SUPERFAMILY SSF143430 6 85 1.7E-24 T 31-10-2018 AF_2434 cd93e67bf2a921f4f508598667d3daf2 92 Gene3D G3DSA:3.30.70.240 2 70 4.6E-28 T 31-10-2018 AF_2434 cd93e67bf2a921f4f508598667d3daf2 92 Pfam PF09827 CRISPR associated protein Cas2 6 75 3.1E-20 T 31-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 AF_2434 cd93e67bf2a921f4f508598667d3daf2 92 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 6 81 5.8E-12 T 31-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 AF_1243 114ae125b1ccd55430f6d61a0840c5d1 244 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 31-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AF_1243 114ae125b1ccd55430f6d61a0840c5d1 244 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 212 1.5E-52 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AF_1243 114ae125b1ccd55430f6d61a0840c5d1 244 SUPERFAMILY SSF53790 1 236 2.22E-73 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AF_1243 114ae125b1ccd55430f6d61a0840c5d1 244 Gene3D G3DSA:3.40.1010.10 1 118 1.7E-45 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AF_1243 114ae125b1ccd55430f6d61a0840c5d1 244 Gene3D G3DSA:3.30.950.10 119 243 3.6E-41 T 31-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AF_1243 114ae125b1ccd55430f6d61a0840c5d1 244 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 3 235 5.5E-97 T 31-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AF_0424 af1d0c95974f0f013324715ab4f6585b 368 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 243 254 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0424 af1d0c95974f0f013324715ab4f6585b 368 Pfam PF01077 Nitrite and sulphite reductase 4Fe-4S domain 130 345 1.5E-39 T 31-10-2018 IPR006067 Nitrite/sulphite reductase 4Fe-4S domain GO:0016491|GO:0020037|GO:0051536|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AF_0424 af1d0c95974f0f013324715ab4f6585b 368 SUPERFAMILY SSF55124 5 124 1.01E-45 T 31-10-2018 IPR036136 Nitrite/Sulfite reductase ferredoxin-like domain superfamily GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AF_0424 af1d0c95974f0f013324715ab4f6585b 368 Gene3D G3DSA:3.30.413.10 132 352 3.6E-108 T 31-10-2018 AF_0424 af1d0c95974f0f013324715ab4f6585b 368 Pfam PF03460 Nitrite/Sulfite reductase ferredoxin-like half domain 48 111 1.8E-11 T 31-10-2018 IPR005117 Nitrite/Sulfite reductase ferredoxin-like domain GO:0016491|GO:0055114 KEGG: 00920+1.8.1.2|MetaCyc: PWY-6683 AF_0424 af1d0c95974f0f013324715ab4f6585b 368 TIGRFAM TIGR02066 dsrB: sulfite reductase, dissimilatory-type beta subunit 24 368 2.8E-187 T 31-10-2018 IPR011808 Sulphite reductase, dissimilatory-type beta subunit GO:0006790|GO:0009055|GO:0018551|GO:0051539 KEGG: 00633+1.8.99.5|KEGG: 00920+1.8.99.5|MetaCyc: PWY-5306|MetaCyc: PWY-5360 AF_0424 af1d0c95974f0f013324715ab4f6585b 368 Gene3D G3DSA:3.30.70.3340 3 118 4.3E-54 T 31-10-2018 AF_0424 af1d0c95974f0f013324715ab4f6585b 368 SUPERFAMILY SSF56014 130 359 2.13E-45 T 31-10-2018 AF_0424 af1d0c95974f0f013324715ab4f6585b 368 SUPERFAMILY SSF54862 212 254 6.75E-10 T 31-10-2018 AF_0424 af1d0c95974f0f013324715ab4f6585b 368 Pfam PF00037 4Fe-4S binding domain 236 254 4.3E-5 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0424 af1d0c95974f0f013324715ab4f6585b 368 Gene3D G3DSA:3.30.70.20 200 258 3.6E-108 T 31-10-2018 AF_1202 a956ac6dafd55daadc4f5e4b73abc74c 165 SUPERFAMILY SSF54862 6 161 9.1E-46 T 31-10-2018 AF_1202 a956ac6dafd55daadc4f5e4b73abc74c 165 Gene3D G3DSA:3.30.70.20 43 164 9.6E-34 T 31-10-2018 AF_1202 a956ac6dafd55daadc4f5e4b73abc74c 165 Gene3D G3DSA:3.30.70.20 2 42 2.3E-5 T 31-10-2018 AF_1202 a956ac6dafd55daadc4f5e4b73abc74c 165 Pfam PF00037 4Fe-4S binding domain 10 28 1.5E-4 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1202 a956ac6dafd55daadc4f5e4b73abc74c 165 Pfam PF13247 4Fe-4S dicluster domain 58 149 7.8E-17 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1202 a956ac6dafd55daadc4f5e4b73abc74c 165 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 96 107 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1137 010b7ec563ba6b00783d7d0cf2844c95 297 Pfam PF12679 ABC-2 family transporter protein 4 297 1.3E-65 T 31-10-2018 IPR032688 ABC-2 family transporter protein GO:0055085 AF_1933 b63feae87606ac4dd82e7a077f4b776f 161 SUPERFAMILY SSF54637 11 157 3.12E-43 T 31-10-2018 IPR029069 HotDog domain superfamily AF_1933 b63feae87606ac4dd82e7a077f4b776f 161 Pfam PF01575 MaoC like domain 19 137 2.6E-35 T 31-10-2018 IPR002539 MaoC-like dehydratase domain AF_1933 b63feae87606ac4dd82e7a077f4b776f 161 Gene3D G3DSA:3.10.129.10 1 161 2.2E-54 T 31-10-2018 AF_1982 2caa04001ac786589d781c220a509ff8 253 Pfam PF00005 ABC transporter 19 163 5.8E-31 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_1982 2caa04001ac786589d781c220a509ff8 253 SUPERFAMILY SSF52540 3 226 3.12E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1982 2caa04001ac786589d781c220a509ff8 253 ProSitePatterns PS00211 ABC transporters family signature. 135 149 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_1982 2caa04001ac786589d781c220a509ff8 253 Gene3D G3DSA:3.40.50.300 1 241 3.1E-65 T 31-10-2018 AF_1982 2caa04001ac786589d781c220a509ff8 253 SMART SM00382 28 218 7.2E-15 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1888 4d5a145411ec33ad7d68d3e9e38a6e97 867 Gene3D G3DSA:2.20.25.410 813 865 9.1E-22 T 31-10-2018 AF_1888 4d5a145411ec33ad7d68d3e9e38a6e97 867 Gene3D G3DSA:2.40.40.20 300 469 4.6E-74 T 31-10-2018 AF_1888 4d5a145411ec33ad7d68d3e9e38a6e97 867 Gene3D G3DSA:1.10.274.100 480 626 1.2E-89 T 31-10-2018 AF_1888 4d5a145411ec33ad7d68d3e9e38a6e97 867 Pfam PF04997 RNA polymerase Rpb1, domain 1 4 308 3.3E-104 T 31-10-2018 IPR007080 RNA polymerase Rpb1, domain 1 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1888 4d5a145411ec33ad7d68d3e9e38a6e97 867 Pfam PF04998 RNA polymerase Rpb1, domain 5 774 840 7.3E-26 T 31-10-2018 IPR007081 RNA polymerase Rpb1, domain 5 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1888 4d5a145411ec33ad7d68d3e9e38a6e97 867 Gene3D G3DSA:3.30.1490.180 343 405 4.6E-74 T 31-10-2018 AF_1888 4d5a145411ec33ad7d68d3e9e38a6e97 867 SMART SM00663 200 502 3.3E-196 T 31-10-2018 IPR006592 RNA polymerase, N-terminal GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1888 4d5a145411ec33ad7d68d3e9e38a6e97 867 Gene3D G3DSA:1.10.132.30 627 775 1.2E-89 T 31-10-2018 IPR038120 RNA polymerase Rpb1, funnel domain superfamily KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1888 4d5a145411ec33ad7d68d3e9e38a6e97 867 Pfam PF00623 RNA polymerase Rpb1, domain 2 310 474 1.8E-66 T 31-10-2018 IPR000722 RNA polymerase, alpha subunit GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1888 4d5a145411ec33ad7d68d3e9e38a6e97 867 SUPERFAMILY SSF64484 2 847 0.0 T 31-10-2018 AF_1888 4d5a145411ec33ad7d68d3e9e38a6e97 867 TIGRFAM TIGR02390 RNA_pol_rpoA1: DNA-directed RNA polymerase subunit A' 4 858 0.0 T 31-10-2018 IPR012758 DNA-directed RNA polymerase subunit A' (Rpo1N) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1888 4d5a145411ec33ad7d68d3e9e38a6e97 867 Gene3D G3DSA:1.20.120.1280 223 273 2.2E-11 T 31-10-2018 AF_1888 4d5a145411ec33ad7d68d3e9e38a6e97 867 Gene3D G3DSA:1.20.120.1280 1 107 6.9E-31 T 31-10-2018 AF_1888 4d5a145411ec33ad7d68d3e9e38a6e97 867 Pfam PF04983 RNA polymerase Rpb1, domain 3 477 633 4.0E-35 T 31-10-2018 IPR007066 RNA polymerase Rpb1, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1888 4d5a145411ec33ad7d68d3e9e38a6e97 867 Pfam PF05000 RNA polymerase Rpb1, domain 4 659 767 2.6E-31 T 31-10-2018 IPR007083 RNA polymerase Rpb1, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_2327 4ac0ae5530c14e2c9c77793d69cbd354 269 TIGRFAM TIGR00507 aroE: shikimate dehydrogenase 3 267 1.6E-105 T 31-10-2018 IPR011342 Shikimate dehydrogenase GO:0004764|GO:0019632|GO:0050661|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AF_2327 4ac0ae5530c14e2c9c77793d69cbd354 269 Gene3D G3DSA:3.40.50.720 97 233 5.7E-81 T 31-10-2018 AF_2327 4ac0ae5530c14e2c9c77793d69cbd354 269 SUPERFAMILY SSF51735 98 267 2.11E-46 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_2327 4ac0ae5530c14e2c9c77793d69cbd354 269 Gene3D G3DSA:3.40.50.10860 4 256 5.7E-81 T 31-10-2018 AF_2327 4ac0ae5530c14e2c9c77793d69cbd354 269 Hamap MF_00222 Shikimate dehydrogenase (NADP(+)) [aroE]. 1 265 33.943 T 31-10-2018 IPR022893 Shikimate dehydrogenase family GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AF_2327 4ac0ae5530c14e2c9c77793d69cbd354 269 SUPERFAMILY SSF53223 2 97 4.09E-25 T 31-10-2018 AF_2327 4ac0ae5530c14e2c9c77793d69cbd354 269 Pfam PF08501 Shikimate dehydrogenase substrate binding domain 6 87 2.0E-28 T 31-10-2018 IPR013708 Shikimate dehydrogenase substrate binding, N-terminal GO:0004764|GO:0055114 KEGG: 00400+1.1.1.25|MetaCyc: PWY-6163 AF_2327 4ac0ae5530c14e2c9c77793d69cbd354 269 Pfam PF01488 Shikimate / quinate 5-dehydrogenase 110 184 4.8E-9 T 31-10-2018 IPR006151 Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase AF_1931 cf1426cd8b2c870437fa3f693af9ace7 237 TIGRFAM TIGR03122 one_C_dehyd_C: formylmethanofuran dehydrogenase subunit C 5 220 5.2E-83 T 31-10-2018 IPR017550 Formylmethanofuran dehydrogenase subunit C GO:0015948|GO:0018493|GO:0046914|GO:0055114 KEGG: 00680+1.2.7.12|MetaCyc: PWY-5209|MetaCyc: PWY-7784 AF_1931 cf1426cd8b2c870437fa3f693af9ace7 237 SUPERFAMILY SSF69336 34 216 8.37E-40 T 31-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 AF_1931 cf1426cd8b2c870437fa3f693af9ace7 237 Gene3D G3DSA:2.160.20.60 82 219 1.7E-11 T 31-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 AF_1931 cf1426cd8b2c870437fa3f693af9ace7 237 Pfam PF01493 GXGXG motif 82 202 1.6E-12 T 31-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 AF_2196 1ce47d510a4b7dfe18ad49fc8553734b 235 Hamap MF_00681 (5-formylfuran-3-yl)methyl phosphate synthase [mfnB]. 1 233 46.348 T 31-10-2018 IPR035081 (5-formylfuran-3-yl)methyl phosphate synthase, archaea GO:0016830|GO:2001120 KEGG: 00680+4.2.3.153|MetaCyc: PWY-5254 AF_2196 1ce47d510a4b7dfe18ad49fc8553734b 235 SUPERFAMILY SSF51569 8 122 1.5E-11 T 31-10-2018 AF_2196 1ce47d510a4b7dfe18ad49fc8553734b 235 SUPERFAMILY SSF51366 80 215 3.45E-5 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AF_2196 1ce47d510a4b7dfe18ad49fc8553734b 235 Pfam PF04476 4-HFC-P synthase 3 229 2.9E-89 T 31-10-2018 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|MetaCyc: PWY-5254 AF_2196 1ce47d510a4b7dfe18ad49fc8553734b 235 PIRSF PIRSF015957 1 235 1.4E-122 T 31-10-2018 IPR007565 (5-formylfuran-3-yl)methyl phosphate synthase KEGG: 00680+4.2.3.153|MetaCyc: PWY-5254 AF_1233 04f2fb6b89254d036f89cb825f28fefa 211 Pfam PF02811 PHP domain 3 81 7.3E-10 T 31-10-2018 IPR004013 PHP domain GO:0003824 AF_1233 04f2fb6b89254d036f89cb825f28fefa 211 Gene3D G3DSA:3.20.20.140 1 209 1.2E-50 T 31-10-2018 AF_1233 04f2fb6b89254d036f89cb825f28fefa 211 SUPERFAMILY SSF89550 1 201 3.14E-41 T 31-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AF_1233 04f2fb6b89254d036f89cb825f28fefa 211 SMART SM00481 2 78 2.6E-25 T 31-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal AF_0596 5f68177b631f314e3b48d2d102c9a488 465 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 43 448 5.3E-149 T 31-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AF_0596 5f68177b631f314e3b48d2d102c9a488 465 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 43 230 1.0E-69 T 31-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AF_0596 5f68177b631f314e3b48d2d102c9a488 465 SUPERFAMILY SSF52413 345 451 2.09E-33 T 31-10-2018 IPR036220 UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily Reactome: R-HSA-173599 AF_0596 5f68177b631f314e3b48d2d102c9a488 465 SUPERFAMILY SSF51735 43 234 2.16E-54 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0596 5f68177b631f314e3b48d2d102c9a488 465 SUPERFAMILY SSF48179 244 338 5.78E-33 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_0596 5f68177b631f314e3b48d2d102c9a488 465 PIRSF PIRSF000124 43 465 2.7E-142 T 31-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AF_0596 5f68177b631f314e3b48d2d102c9a488 465 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 244 336 1.0E-38 T 31-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AF_0596 5f68177b631f314e3b48d2d102c9a488 465 PIRSF PIRSF500134 43 461 2.7E-151 T 31-10-2018 IPR028357 UDP-glucose 6-dehydrogenase, bacterial type GO:0000271|GO:0003979 KEGG: 00040+1.1.1.22|KEGG: 00053+1.1.1.22|KEGG: 00520+1.1.1.22|MetaCyc: PWY-7346|MetaCyc: PWY-7820 AF_0596 5f68177b631f314e3b48d2d102c9a488 465 Gene3D G3DSA:3.40.50.720 259 465 1.2E-80 T 31-10-2018 AF_0596 5f68177b631f314e3b48d2d102c9a488 465 Gene3D G3DSA:3.40.50.720 43 258 1.8E-77 T 31-10-2018 AF_0596 5f68177b631f314e3b48d2d102c9a488 465 SMART SM00984 359 453 2.6E-42 T 31-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AF_0596 5f68177b631f314e3b48d2d102c9a488 465 Pfam PF03720 UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain 360 450 1.9E-27 T 31-10-2018 IPR014027 UDP-glucose/GDP-mannose dehydrogenase, C-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AF_0376 f537ba734237e7a42e33f25e9cd62429 470 SUPERFAMILY SSF51717 132 320 4.87E-14 T 31-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AF_0376 f537ba734237e7a42e33f25e9cd62429 470 PIRSF PIRSF000376 1 470 1.1E-222 T 31-10-2018 IPR016218 Acetyl-CoA decarbonylase/synthase complex, gamma subunit GO:0005506|GO:0008168|GO:0046356 AF_0376 f537ba734237e7a42e33f25e9cd62429 470 Hamap MF_01136 Acetyl-CoA decarbonylase/synthase complex subunit gamma [cdhE]. 2 468 53.188 T 31-10-2018 IPR023427 Acetyl-CoA decarbonylase/synthase complex, gamma subunit, archaea GO:0006084|GO:0008168 AF_0376 f537ba734237e7a42e33f25e9cd62429 470 Pfam PF04060 Putative Fe-S cluster 13 45 1.8E-11 T 31-10-2018 IPR007202 4Fe-4S domain GO:0051536 AF_0376 f537ba734237e7a42e33f25e9cd62429 470 Gene3D G3DSA:3.20.20.20 69 338 7.4E-82 T 31-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AF_0376 f537ba734237e7a42e33f25e9cd62429 470 Gene3D G3DSA:1.10.15.40 4 59 4.5E-15 T 31-10-2018 AF_0376 f537ba734237e7a42e33f25e9cd62429 470 Gene3D G3DSA:3.40.50.11600 339 467 1.2E-47 T 31-10-2018 AF_0376 f537ba734237e7a42e33f25e9cd62429 470 Pfam PF03599 CO dehydrogenase/acetyl-CoA synthase delta subunit 73 462 7.0E-165 T 31-10-2018 IPR016041 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel AF_1897 2e60306f453f2b62a437b66d2e1c5d8d 355 Pfam PF00535 Glycosyl transferase family 2 9 90 2.1E-9 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AF_1897 2e60306f453f2b62a437b66d2e1c5d8d 355 Gene3D G3DSA:3.90.550.10 7 193 3.6E-18 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_1897 2e60306f453f2b62a437b66d2e1c5d8d 355 SUPERFAMILY SSF53448 9 267 2.88E-29 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_1897 2e60306f453f2b62a437b66d2e1c5d8d 355 Pfam PF13632 Glycosyl transferase family group 2 109 263 6.6E-14 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AF_2329 7b71fb97d44adc06b1cda664c41df797 457 ProSitePatterns PS00571 Amidases signature. 139 170 - T 31-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 AF_2329 7b71fb97d44adc06b1cda664c41df797 457 Gene3D G3DSA:3.90.1300.10 2 454 3.7E-173 T 31-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AF_2329 7b71fb97d44adc06b1cda664c41df797 457 Pfam PF01425 Amidase 18 443 1.1E-158 T 31-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AF_2329 7b71fb97d44adc06b1cda664c41df797 457 TIGRFAM TIGR00132 gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit 4 453 1.3E-198 T 31-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AF_2329 7b71fb97d44adc06b1cda664c41df797 457 Hamap MF_00120 Glutamyl-tRNA(Gln) amidotransferase subunit A [gatA]. 6 454 91.126 T 31-10-2018 IPR004412 Glutamyl-tRNA(Gln) amidotransferase A subunit GO:0006412|GO:0030956|GO:0050567 KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AF_2329 7b71fb97d44adc06b1cda664c41df797 457 SUPERFAMILY SSF75304 15 452 2.88E-147 T 31-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AF_0704 18b016208acbf0ad59f9e3f3cf3087cc 273 Gene3D G3DSA:3.30.300.110 1 80 6.0E-22 T 31-10-2018 AF_0704 18b016208acbf0ad59f9e3f3cf3087cc 273 Gene3D G3DSA:3.40.50.150 82 273 7.5E-49 T 31-10-2018 AF_0704 18b016208acbf0ad59f9e3f3cf3087cc 273 Pfam PF02475 Met-10+ like-protein 22 221 1.0E-72 T 31-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 AF_0704 18b016208acbf0ad59f9e3f3cf3087cc 273 SUPERFAMILY SSF53335 13 272 2.37E-63 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_1336 82e06472a5d9bb66a7f8a884cbd93076 290 Hamap MF_00024 Cobalamin biosynthesis protein CbiB [cbiB]. 1 288 65.317 T 31-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 AF_1336 82e06472a5d9bb66a7f8a884cbd93076 290 TIGRFAM TIGR00380 cobD: cobalamin biosynthesis protein CobD 3 284 7.4E-124 T 31-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 AF_1336 82e06472a5d9bb66a7f8a884cbd93076 290 Pfam PF03186 CobD/Cbib protein 9 261 7.0E-75 T 31-10-2018 IPR004485 Cobalamin biosynthesis CobD/CbiB GO:0009236|GO:0016021|GO:0048472 AF_1186 95421804d11424a89ee70db562351f12 491 Pfam PF00571 CBS domain 375 428 7.1E-14 T 31-10-2018 IPR000644 CBS domain AF_1186 95421804d11424a89ee70db562351f12 491 Pfam PF00571 CBS domain 435 489 2.7E-15 T 31-10-2018 IPR000644 CBS domain AF_1186 95421804d11424a89ee70db562351f12 491 SMART SM00116 442 490 6.8E-13 T 31-10-2018 IPR000644 CBS domain AF_1186 95421804d11424a89ee70db562351f12 491 SMART SM00116 381 428 2.1E-13 T 31-10-2018 IPR000644 CBS domain AF_1186 95421804d11424a89ee70db562351f12 491 PIRSF PIRSF004698 1 491 5.6E-267 T 31-10-2018 IPR016426 Uncharacterised conserved protein UCP004698, CBS-type AF_1186 95421804d11424a89ee70db562351f12 491 ProDom PD011569 METAL-BINDING IRON IRON-SULFUR 4FE-4S FERREDOXIN OXIDOREDUCTASE DOMAIN ELECTRON METHANOGENESIS A 14 269 7.0E-151 T 31-10-2018 IPR002708 Homocysteine biosynthesis enzyme, sulfur-incorporation AF_1186 95421804d11424a89ee70db562351f12 491 Gene3D G3DSA:3.10.580.10 429 491 7.1E-17 T 31-10-2018 AF_1186 95421804d11424a89ee70db562351f12 491 Gene3D G3DSA:3.10.580.10 335 428 1.3E-16 T 31-10-2018 AF_1186 95421804d11424a89ee70db562351f12 491 Pfam PF01837 Homocysteine biosynthesis enzyme, sulfur-incorporation 17 351 1.4E-144 T 31-10-2018 IPR002708 Homocysteine biosynthesis enzyme, sulfur-incorporation AF_1186 95421804d11424a89ee70db562351f12 491 SUPERFAMILY SSF54631 372 490 2.99E-32 T 31-10-2018 AF_0776 4ffe640d57cdd0889aee5e0aefe39b97 323 SUPERFAMILY SSF52374 2 319 5.63E-82 T 31-10-2018 AF_0776 4ffe640d57cdd0889aee5e0aefe39b97 323 Pfam PF00579 tRNA synthetases class I (W and Y) 30 312 6.2E-61 T 31-10-2018 IPR002305 Aminoacyl-tRNA synthetase, class Ic GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_0776 4ffe640d57cdd0889aee5e0aefe39b97 323 ProSitePatterns PS00178 Aminoacyl-transfer RNA synthetases class-I signature. 41 50 - T 31-10-2018 IPR001412 Aminoacyl-tRNA synthetase, class I, conserved site GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_0776 4ffe640d57cdd0889aee5e0aefe39b97 323 Hamap MF_02008 Tyrosine--tRNA ligase [tyrS]. 4 320 55.195 T 31-10-2018 IPR023684 Tyrosine-tRNA ligase, type 3 GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AF_0776 4ffe640d57cdd0889aee5e0aefe39b97 323 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 167 189 4.3E-20 T 31-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AF_0776 4ffe640d57cdd0889aee5e0aefe39b97 323 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 200 212 4.3E-20 T 31-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AF_0776 4ffe640d57cdd0889aee5e0aefe39b97 323 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 150 165 4.3E-20 T 31-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AF_0776 4ffe640d57cdd0889aee5e0aefe39b97 323 PRINTS PR01040 Tyrosyl-tRNA synthetase signature 44 66 4.3E-20 T 31-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AF_0776 4ffe640d57cdd0889aee5e0aefe39b97 323 PIRSF PIRSF006588 1 322 6.9E-130 T 31-10-2018 IPR023617 Tyrosine-tRNA ligase, archaeal/eukaryotic-type GO:0004831 KEGG: 00970+6.1.1.1 AF_0776 4ffe640d57cdd0889aee5e0aefe39b97 323 Gene3D G3DSA:3.40.50.620 1 205 2.2E-84 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_0776 4ffe640d57cdd0889aee5e0aefe39b97 323 Gene3D G3DSA:1.10.240.10 206 322 5.0E-41 T 31-10-2018 AF_0776 4ffe640d57cdd0889aee5e0aefe39b97 323 TIGRFAM TIGR00234 tyrS: tyrosine--tRNA ligase 2 318 2.1E-81 T 31-10-2018 IPR002307 Tyrosine-tRNA ligase GO:0000166|GO:0004831|GO:0005524|GO:0005737|GO:0006437 KEGG: 00970+6.1.1.1 AF_0978 74bc75da19788be5e1f627b1b2ae4cbd 120 Gene3D G3DSA:3.30.70.120 12 120 2.2E-45 T 31-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AF_0978 74bc75da19788be5e1f627b1b2ae4cbd 120 Pfam PF00543 Nitrogen regulatory protein P-II 15 116 6.5E-38 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AF_0978 74bc75da19788be5e1f627b1b2ae4cbd 120 PRINTS PR00340 P-II protein signature 34 52 3.8E-39 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AF_0978 74bc75da19788be5e1f627b1b2ae4cbd 120 PRINTS PR00340 P-II protein signature 13 28 3.8E-39 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AF_0978 74bc75da19788be5e1f627b1b2ae4cbd 120 PRINTS PR00340 P-II protein signature 63 86 3.8E-39 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AF_0978 74bc75da19788be5e1f627b1b2ae4cbd 120 PRINTS PR00340 P-II protein signature 94 114 3.8E-39 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AF_0978 74bc75da19788be5e1f627b1b2ae4cbd 120 SUPERFAMILY SSF54913 12 118 1.75E-39 T 31-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta AF_0978 74bc75da19788be5e1f627b1b2ae4cbd 120 SMART SM00938 15 116 7.4E-56 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AF_0978 74bc75da19788be5e1f627b1b2ae4cbd 120 ProSitePatterns PS00638 P-II protein C-terminal region signature. 94 107 - T 31-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 AF_1564 1f6c808824db7aabe727ff24af561f9f 215 Gene3D G3DSA:1.10.10.10 156 212 5.3E-11 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1564 1f6c808824db7aabe727ff24af561f9f 215 Gene3D G3DSA:1.10.10.10 84 146 2.6E-13 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1564 1f6c808824db7aabe727ff24af561f9f 215 SUPERFAMILY SSF46785 153 214 2.23E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1564 1f6c808824db7aabe727ff24af561f9f 215 SMART SM00418 78 170 6.9E-4 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_1564 1f6c808824db7aabe727ff24af561f9f 215 Pfam PF01022 Bacterial regulatory protein, arsR family 86 132 3.0E-13 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_1564 1f6c808824db7aabe727ff24af561f9f 215 SUPERFAMILY SSF46785 79 149 2.98E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1564 1f6c808824db7aabe727ff24af561f9f 215 Pfam PF13412 Winged helix-turn-helix DNA-binding 158 200 1.1E-13 T 31-10-2018 AF_1167 1a18d3a0715e9365d4cbb337c5acf389 472 SUPERFAMILY SSF52540 79 353 1.02E-84 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1167 1a18d3a0715e9365d4cbb337c5acf389 472 PIRSF PIRSF039114 1 464 2.5E-254 T 31-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AF_1167 1a18d3a0715e9365d4cbb337c5acf389 472 SUPERFAMILY SSF50615 2 77 4.97E-7 T 31-10-2018 IPR036121 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AF_1167 1a18d3a0715e9365d4cbb337c5acf389 472 TIGRFAM TIGR01041 ATP_syn_B_arch: ATP synthase archaeal, B subunit 5 460 8.1E-270 T 31-10-2018 IPR005724 ATPase, A1 complex, beta subunit GO:0015986|GO:0033178|GO:0046933 AF_1167 1a18d3a0715e9365d4cbb337c5acf389 472 Hamap MF_00310 V-type ATP synthase beta chain [atpB]. 3 458 61.876 T 31-10-2018 IPR022879 V-type ATP synthase regulatory subunit B/beta Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AF_1167 1a18d3a0715e9365d4cbb337c5acf389 472 Pfam PF00006 ATP synthase alpha/beta family, nucleotide-binding domain 131 349 4.4E-67 T 31-10-2018 IPR000194 ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AF_1167 1a18d3a0715e9365d4cbb337c5acf389 472 SUPERFAMILY SSF47917 360 422 9.94E-9 T 31-10-2018 AF_1167 1a18d3a0715e9365d4cbb337c5acf389 472 Gene3D G3DSA:3.40.50.12240 14 461 3.1E-186 T 31-10-2018 AF_1167 1a18d3a0715e9365d4cbb337c5acf389 472 ProSitePatterns PS00152 ATP synthase alpha and beta subunits signature. 340 349 - T 31-10-2018 IPR020003 ATPase, alpha/beta subunit, nucleotide-binding domain, active site GO:0005524 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AF_1167 1a18d3a0715e9365d4cbb337c5acf389 472 Pfam PF02874 ATP synthase alpha/beta family, beta-barrel domain 9 74 1.7E-15 T 31-10-2018 IPR004100 ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain GO:0046034|GO:1902600 KEGG: 00190+3.6.3.14|KEGG: 00195+3.6.3.14|MetaCyc: PWY-7980 AF_0231 4c88206be59aab8e7f6539b575dae03b 264 SMART SM00079 39 264 8.1E-6 T 31-10-2018 IPR001320 Ionotropic glutamate receptor GO:0004970|GO:0016020 AF_0231 4c88206be59aab8e7f6539b575dae03b 264 Gene3D G3DSA:3.40.190.10 124 227 2.6E-82 T 31-10-2018 AF_0231 4c88206be59aab8e7f6539b575dae03b 264 ProSitePatterns PS01039 Bacterial extracellular solute-binding proteins, family 3 signature. 63 76 - T 31-10-2018 IPR018313 Solute-binding protein family 3, conserved site AF_0231 4c88206be59aab8e7f6539b575dae03b 264 SMART SM00062 39 264 3.6E-97 T 31-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AF_0231 4c88206be59aab8e7f6539b575dae03b 264 SUPERFAMILY SSF53850 1 263 1.82E-82 T 31-10-2018 AF_0231 4c88206be59aab8e7f6539b575dae03b 264 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 40 264 1.1E-78 T 31-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AF_0231 4c88206be59aab8e7f6539b575dae03b 264 Gene3D G3DSA:3.40.190.10 38 262 2.6E-82 T 31-10-2018 AF_0050 ec59a97424e802e89e3b6f185479fbd5 399 Gene3D G3DSA:3.30.300.280 12 392 2.6E-160 T 31-10-2018 AF_0050 ec59a97424e802e89e3b6f185479fbd5 399 Gene3D G3DSA:3.30.300.340 14 280 2.6E-160 T 31-10-2018 AF_0050 ec59a97424e802e89e3b6f185479fbd5 399 ProDom PD011777 SYNTHETASE TRANSFERASE METHIONINE ADENOSYLTRANSFERASE S-ADENOSYLMETHIONINE NUCLEOTIDE-BINDING METABOLISM ATP-BINDING MAGNESIUM ONE-CARBON 20 384 0.0 T 31-10-2018 AF_0050 ec59a97424e802e89e3b6f185479fbd5 399 Hamap MF_00136 S-adenosylmethionine synthase [mat]. 1 399 52.27 T 31-10-2018 IPR002795 S-adenosylmethionine synthetase, archaea GO:0004478|GO:0005524|GO:0006730 KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 AF_0050 ec59a97424e802e89e3b6f185479fbd5 399 Pfam PF01941 S-adenosylmethionine synthetase (AdoMet synthetase) 3 395 1.0E-178 T 31-10-2018 IPR027790 S-adenosylmethionine synthase KEGG: 00270+2.5.1.6|MetaCyc: PWY-5041|MetaCyc: PWY-5912 AF_0050 ec59a97424e802e89e3b6f185479fbd5 399 Gene3D G3DSA:3.30.300.10 26 152 2.6E-160 T 31-10-2018 AF_1772 bf700eca59e67f23aab1c36844f38fda 569 Gene3D G3DSA:3.30.300.310 463 567 4.9E-37 T 31-10-2018 AF_1772 bf700eca59e67f23aab1c36844f38fda 569 Pfam PF13193 AMP-binding enzyme C-terminal domain 476 553 6.6E-23 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AF_1772 bf700eca59e67f23aab1c36844f38fda 569 ProSitePatterns PS00455 Putative AMP-binding domain signature. 220 231 - T 31-10-2018 IPR020845 AMP-binding, conserved site AF_1772 bf700eca59e67f23aab1c36844f38fda 569 Gene3D G3DSA:3.40.50.12780 35 460 1.6E-125 T 31-10-2018 AF_1772 bf700eca59e67f23aab1c36844f38fda 569 SUPERFAMILY SSF56801 25 563 7.98E-170 T 31-10-2018 AF_1772 bf700eca59e67f23aab1c36844f38fda 569 Pfam PF00501 AMP-binding enzyme 44 466 8.5E-119 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_0894 f6633e3828c96e948108c4c1c177c888 549 Pfam PF05746 DALR anticodon binding domain 433 549 3.6E-33 T 31-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 AF_0894 f6633e3828c96e948108c4c1c177c888 549 Hamap MF_00123 Arginine--tRNA ligase [argS]. 3 549 28.59 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AF_0894 f6633e3828c96e948108c4c1c177c888 549 Gene3D G3DSA:1.10.730.10 433 549 2.6E-32 T 31-10-2018 AF_0894 f6633e3828c96e948108c4c1c177c888 549 Gene3D G3DSA:3.40.50.620 104 432 2.8E-100 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_0894 f6633e3828c96e948108c4c1c177c888 549 SUPERFAMILY SSF47323 429 549 2.03E-32 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_0894 f6633e3828c96e948108c4c1c177c888 549 SUPERFAMILY SSF55190 8 98 5.75E-17 T 31-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 AF_0894 f6633e3828c96e948108c4c1c177c888 549 Pfam PF03485 Arginyl tRNA synthetase N terminal domain 23 77 2.3E-13 T 31-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AF_0894 f6633e3828c96e948108c4c1c177c888 549 Gene3D G3DSA:3.30.1360.70 3 102 5.6E-22 T 31-10-2018 IPR036695 Arginyl tRNA synthetase N-terminal domain superfamily GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19 AF_0894 f6633e3828c96e948108c4c1c177c888 549 SMART SM00836 433 549 4.9E-38 T 31-10-2018 IPR008909 DALR anticodon binding GO:0004814|GO:0005524|GO:0006420 AF_0894 f6633e3828c96e948108c4c1c177c888 549 TIGRFAM TIGR00456 argS: arginine--tRNA ligase 24 549 3.4E-206 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AF_0894 f6633e3828c96e948108c4c1c177c888 549 SMART SM01016 3 78 1.1E-17 T 31-10-2018 IPR005148 Arginyl tRNA synthetase N-terminal domain GO:0000166|GO:0004814|GO:0005524|GO:0005737|GO:0006420 KEGG: 00970+6.1.1.19|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AF_0894 f6633e3828c96e948108c4c1c177c888 549 SUPERFAMILY SSF52374 104 426 2.76E-81 T 31-10-2018 AF_0894 f6633e3828c96e948108c4c1c177c888 549 Pfam PF00750 tRNA synthetases class I (R) 87 419 2.2E-36 T 31-10-2018 IPR035684 Arginyl-tRNA synthetase, catalytic core domain KEGG: 00970+6.1.1.19 AF_0894 f6633e3828c96e948108c4c1c177c888 549 PRINTS PR01038 Arginyl-tRNA synthetase signature 120 136 1.8E-23 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AF_0894 f6633e3828c96e948108c4c1c177c888 549 PRINTS PR01038 Arginyl-tRNA synthetase signature 285 306 1.8E-23 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AF_0894 f6633e3828c96e948108c4c1c177c888 549 PRINTS PR01038 Arginyl-tRNA synthetase signature 105 120 1.8E-23 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AF_0894 f6633e3828c96e948108c4c1c177c888 549 PRINTS PR01038 Arginyl-tRNA synthetase signature 144 157 1.8E-23 T 31-10-2018 IPR001278 Arginine-tRNA ligase GO:0004814|GO:0005524|GO:0006420 KEGG: 00970+6.1.1.19 AF_1776 07ca9e1f88ee67388779403d736f3103 40 Pfam PF03911 Sec61beta family 1 36 9.6E-14 T 31-10-2018 IPR016482 Protein transport protein SecG/Sec61-beta/Sbh Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AF_1776 07ca9e1f88ee67388779403d736f3103 40 ProDom PD048325 SUBUNIT PREPROTEIN TRANSLOCASE SECG HOMOLOG TRANSLOCATION MEMBRANE SEC61 TRANSMEMBRANE BETA 1 34 4.0E-12 T 31-10-2018 AF_0333 2866e464b6d303b980595d3de001b401 500 SUPERFAMILY SSF47203 267 479 1.59E-72 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AF_0333 2866e464b6d303b980595d3de001b401 500 Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal 7 276 1.0E-109 T 31-10-2018 IPR024674 HpaB/PvcC/4-BUDH N-terminal AF_0333 2866e464b6d303b980595d3de001b401 500 Gene3D G3DSA:2.40.110.10 147 278 3.3E-48 T 31-10-2018 AF_0333 2866e464b6d303b980595d3de001b401 500 SUPERFAMILY SSF56645 4 277 8.51E-92 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AF_0333 2866e464b6d303b980595d3de001b401 500 Gene3D G3DSA:1.20.140.10 280 479 1.2E-82 T 31-10-2018 AF_0333 2866e464b6d303b980595d3de001b401 500 Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal 284 478 4.2E-71 T 31-10-2018 IPR024719 HpaB/PvcC/4-BUDH C-terminal AF_0333 2866e464b6d303b980595d3de001b401 500 Gene3D G3DSA:1.10.3140.10 4 145 4.4E-62 T 31-10-2018 AF_0333 2866e464b6d303b980595d3de001b401 500 PIRSF PIRSF000331 2 489 3.5E-186 T 31-10-2018 IPR004925 HpaB/PvcC/4-BUDH AF_1041 e0b981856f6d3d46274ac5e1e9ce3912 349 SUPERFAMILY SSF52172 1 122 1.99E-32 T 31-10-2018 IPR011006 CheY-like superfamily AF_1041 e0b981856f6d3d46274ac5e1e9ce3912 349 Gene3D G3DSA:3.40.50.2300 1 135 6.4E-36 T 31-10-2018 AF_1041 e0b981856f6d3d46274ac5e1e9ce3912 349 PIRSF PIRSF000876 1 346 3.5E-131 T 31-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AF_1041 e0b981856f6d3d46274ac5e1e9ce3912 349 Hamap MF_00099 Chemotaxis response regulator protein-glutamate methylesterase [cheB]. 1 343 40.554 T 31-10-2018 IPR008248 Signal transduction response regulator, chemotaxis, CheB GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AF_1041 e0b981856f6d3d46274ac5e1e9ce3912 349 Pfam PF01339 CheB methylesterase 159 338 3.7E-61 T 31-10-2018 IPR000673 Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase GO:0000156|GO:0000160|GO:0005737|GO:0006935|GO:0008984 AF_1041 e0b981856f6d3d46274ac5e1e9ce3912 349 SUPERFAMILY SSF52738 158 342 4.32E-66 T 31-10-2018 IPR035909 Methylesterase CheB, C-terminal AF_1041 e0b981856f6d3d46274ac5e1e9ce3912 349 SMART SM00448 1 115 8.5E-34 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_1041 e0b981856f6d3d46274ac5e1e9ce3912 349 Pfam PF00072 Response regulator receiver domain 3 104 3.3E-27 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_1041 e0b981856f6d3d46274ac5e1e9ce3912 349 Gene3D G3DSA:3.40.50.180 151 346 6.8E-70 T 31-10-2018 IPR035909 Methylesterase CheB, C-terminal AF_0475 ca4e12aa373e8e9266e13f9b2f7e49ba 370 Gene3D G3DSA:1.20.1530.20 24 362 1.7E-22 T 31-10-2018 IPR038770 Sodium/solute symporter superfamily AF_0475 ca4e12aa373e8e9266e13f9b2f7e49ba 370 TIGRFAM TIGR00832 acr3: arsenical-resistance protein 30 360 5.8E-137 T 31-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 AF_0475 ca4e12aa373e8e9266e13f9b2f7e49ba 370 Pfam PF01758 Sodium Bile acid symporter family 75 272 1.7E-67 T 31-10-2018 IPR002657 Bile acid:sodium symporter/arsenical resistance protein Acr3 GO:0016020 AF_0475 ca4e12aa373e8e9266e13f9b2f7e49ba 370 PIRSF PIRSF005508 13 370 2.0E-133 T 31-10-2018 IPR004706 Arsenical-resistance protein Acr3 GO:0015103|GO:0015297|GO:0016021 AF_1511 ee195f02079a7018db801b14c07a07a0 881 Gene3D G3DSA:3.30.1490.20 693 762 5.3E-65 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AF_1511 ee195f02079a7018db801b14c07a07a0 881 TIGRFAM TIGR02717 AcCoA-syn-alpha: acetyl coenzyme A synthetase (ADP forming), alpha domain 191 640 2.3E-181 T 31-10-2018 IPR014089 Acetate-CoA ligase [ADP-forming], alpha domain KEGG: 00010+6.2.1.13|KEGG: 00620+6.2.1.13|KEGG: 00640+6.2.1.13|MetaCyc: PWY-5483|MetaCyc: PWY-5535 AF_1511 ee195f02079a7018db801b14c07a07a0 881 SUPERFAMILY SSF52210 486 645 1.11E-33 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1511 ee195f02079a7018db801b14c07a07a0 881 SUPERFAMILY SSF51735 187 325 1.24E-33 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1511 ee195f02079a7018db801b14c07a07a0 881 Pfam PF13607 Succinyl-CoA ligase like flavodoxin domain 343 480 8.6E-49 T 31-10-2018 IPR032875 Succinyl-CoA synthetase-like, flavodoxin domain AF_1511 ee195f02079a7018db801b14c07a07a0 881 SUPERFAMILY SSF56059 679 880 1.24E-35 T 31-10-2018 AF_1511 ee195f02079a7018db801b14c07a07a0 881 Gene3D G3DSA:3.40.50.261 483 647 8.8E-47 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1511 ee195f02079a7018db801b14c07a07a0 881 SMART SM00881 194 289 5.2E-33 T 31-10-2018 IPR003781 CoA-binding GO:0048037 AF_1511 ee195f02079a7018db801b14c07a07a0 881 Gene3D G3DSA:3.40.630.30 12 189 1.5E-31 T 31-10-2018 AF_1511 ee195f02079a7018db801b14c07a07a0 881 Gene3D G3DSA:3.40.50.720 190 318 5.4E-41 T 31-10-2018 AF_1511 ee195f02079a7018db801b14c07a07a0 881 Pfam PF00583 Acetyltransferase (GNAT) family 67 152 2.6E-14 T 31-10-2018 IPR000182 GNAT domain AF_1511 ee195f02079a7018db801b14c07a07a0 881 Gene3D G3DSA:3.30.470.20 675 875 5.3E-65 T 31-10-2018 AF_1511 ee195f02079a7018db801b14c07a07a0 881 SUPERFAMILY SSF52210 318 487 1.26E-40 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1511 ee195f02079a7018db801b14c07a07a0 881 Pfam PF13549 ATP-grasp domain 671 877 2.1E-63 T 31-10-2018 AF_1511 ee195f02079a7018db801b14c07a07a0 881 Gene3D G3DSA:3.40.50.261 320 482 8.1E-55 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1511 ee195f02079a7018db801b14c07a07a0 881 Pfam PF13380 CoA binding domain 199 324 3.0E-19 T 31-10-2018 IPR003781 CoA-binding GO:0048037 AF_1511 ee195f02079a7018db801b14c07a07a0 881 SUPERFAMILY SSF55729 20 155 2.44E-23 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase AF_0866 6734e12f6d0b4b6672b7f8e33ba00940 492 ProSitePatterns PS00445 FGGY family of carbohydrate kinases signature 2. 363 383 - T 31-10-2018 IPR018483 Carbohydrate kinase, FGGY, conserved site GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AF_0866 6734e12f6d0b4b6672b7f8e33ba00940 492 SUPERFAMILY SSF53067 258 482 7.03E-45 T 31-10-2018 AF_0866 6734e12f6d0b4b6672b7f8e33ba00940 492 SUPERFAMILY SSF53067 4 259 8.74E-50 T 31-10-2018 AF_0866 6734e12f6d0b4b6672b7f8e33ba00940 492 PIRSF PIRSF000538 1 491 1.3E-96 T 31-10-2018 IPR000577 Carbohydrate kinase, FGGY GO:0005975|GO:0016773 KEGG: 00561+2.7.1.30|MetaCyc: PWY-4261 AF_0866 6734e12f6d0b4b6672b7f8e33ba00940 492 Pfam PF02782 FGGY family of carbohydrate kinases, C-terminal domain 266 451 1.4E-25 T 31-10-2018 IPR018485 Carbohydrate kinase, FGGY, C-terminal GO:0005975|GO:0016773 AF_0866 6734e12f6d0b4b6672b7f8e33ba00940 492 Gene3D G3DSA:3.30.420.40 1 256 6.6E-61 T 31-10-2018 AF_0866 6734e12f6d0b4b6672b7f8e33ba00940 492 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 1 110 1.4E-17 T 31-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 AF_0866 6734e12f6d0b4b6672b7f8e33ba00940 492 Pfam PF00370 FGGY family of carbohydrate kinases, N-terminal domain 131 240 4.2E-21 T 31-10-2018 IPR018484 Carbohydrate kinase, FGGY, N-terminal GO:0005975|GO:0016773 AF_0866 6734e12f6d0b4b6672b7f8e33ba00940 492 Gene3D G3DSA:3.30.420.40 258 492 5.7E-53 T 31-10-2018 AF_0185 d6c165e74b20b5528b713aeab8ee6436 153 Gene3D G3DSA:3.90.1010.10 1 153 9.1E-73 T 31-10-2018 AF_0185 d6c165e74b20b5528b713aeab8ee6436 153 Pfam PF01592 NifU-like N terminal domain 1 122 2.1E-52 T 31-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 AF_0185 d6c165e74b20b5528b713aeab8ee6436 153 SUPERFAMILY SSF82649 4 125 4.45E-47 T 31-10-2018 AF_0185 d6c165e74b20b5528b713aeab8ee6436 153 TIGRFAM TIGR03419 NifU_clost: FeS cluster assembly scaffold protein NifU 2 121 3.1E-63 T 31-10-2018 IPR017787 NIF system FeS cluster assembly, NifU-like AF_0565 d6c165e74b20b5528b713aeab8ee6436 153 Gene3D G3DSA:3.90.1010.10 1 153 9.1E-73 T 31-10-2018 AF_0565 d6c165e74b20b5528b713aeab8ee6436 153 Pfam PF01592 NifU-like N terminal domain 1 122 2.1E-52 T 31-10-2018 IPR002871 NIF system FeS cluster assembly, NifU, N-terminal GO:0005506|GO:0016226|GO:0051536 Reactome: R-HSA-1362409 AF_0565 d6c165e74b20b5528b713aeab8ee6436 153 SUPERFAMILY SSF82649 4 125 4.45E-47 T 31-10-2018 AF_0565 d6c165e74b20b5528b713aeab8ee6436 153 TIGRFAM TIGR03419 NifU_clost: FeS cluster assembly scaffold protein NifU 2 121 3.1E-63 T 31-10-2018 IPR017787 NIF system FeS cluster assembly, NifU-like AF_1985 b31718ab1034c661ecc172ed45ae6a3d 332 SUPERFAMILY SSF51735 3 184 2.25E-71 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1985 b31718ab1034c661ecc172ed45ae6a3d 332 Hamap MF_00435 Ketol-acid reductoisomerase (NADP(+)) [ilvC]. 2 330 43.184 T 31-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AF_1985 b31718ab1034c661ecc172ed45ae6a3d 332 Gene3D G3DSA:1.10.3730.40 184 332 4.2E-70 T 31-10-2018 AF_1985 b31718ab1034c661ecc172ed45ae6a3d 332 TIGRFAM TIGR00465 ilvC: ketol-acid reductoisomerase 15 330 5.3E-152 T 31-10-2018 IPR013023 Ketol-acid reductoisomerase GO:0009082|GO:0016491|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AF_1985 b31718ab1034c661ecc172ed45ae6a3d 332 Gene3D G3DSA:3.40.50.720 2 183 6.5E-77 T 31-10-2018 AF_1985 b31718ab1034c661ecc172ed45ae6a3d 332 SUPERFAMILY SSF48179 185 330 2.04E-67 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_1985 b31718ab1034c661ecc172ed45ae6a3d 332 Pfam PF07991 Acetohydroxy acid isomeroreductase, NADPH-binding domain 15 179 1.5E-75 T 31-10-2018 IPR013116 Ketol-acid reductoisomerase, N-terminal KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AF_1985 b31718ab1034c661ecc172ed45ae6a3d 332 Pfam PF01450 Acetohydroxy acid isomeroreductase, catalytic domain 185 328 2.1E-63 T 31-10-2018 IPR000506 Ketol-acid reductoisomerase, C-terminal GO:0004455|GO:0009082|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AF_1985 b31718ab1034c661ecc172ed45ae6a3d 332 PIRSF PIRSF000116 204 331 5.0E-17 T 31-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AF_1985 b31718ab1034c661ecc172ed45ae6a3d 332 PIRSF PIRSF000116 4 207 8.5E-41 T 31-10-2018 IPR014359 Ketol-acid reductoisomerase, prokaryotic GO:0004455|GO:0009082|GO:0050661|GO:0055114 KEGG: 00290+1.1.1.86|KEGG: 00770+1.1.1.86|MetaCyc: PWY-5103|MetaCyc: PWY-7111 AF_0563 a9356ea7d95160fa0af5e96693dd898f 94 Gene3D G3DSA:3.40.1260.10 1 94 4.5E-25 T 31-10-2018 IPR027396 DsrEFH-like AF_0563 a9356ea7d95160fa0af5e96693dd898f 94 SUPERFAMILY SSF75169 2 94 2.19E-17 T 31-10-2018 IPR027396 DsrEFH-like AF_0563 a9356ea7d95160fa0af5e96693dd898f 94 Pfam PF02635 DsrE/DsrF-like family 3 94 3.2E-14 T 31-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein AF_1338 161264b8a90f40a937a88db2441db87f 464 Gene3D G3DSA:3.40.50.880 247 412 1.2E-13 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_1338 161264b8a90f40a937a88db2441db87f 464 Pfam PF07685 CobB/CobQ-like glutamine amidotransferase domain 247 426 2.4E-47 T 31-10-2018 IPR011698 CobB/CobQ-like glutamine amidotransferase GO:0003824|GO:0009236 AF_1338 161264b8a90f40a937a88db2441db87f 464 SUPERFAMILY SSF52317 191 420 2.62E-24 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_1338 161264b8a90f40a937a88db2441db87f 464 TIGRFAM TIGR00313 cobQ: cobyric acid synthase CobQ 4 462 3.5E-219 T 31-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 AF_1338 161264b8a90f40a937a88db2441db87f 464 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 228 5.7E-22 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AF_1338 161264b8a90f40a937a88db2441db87f 464 SUPERFAMILY SSF52540 1 229 9.35E-50 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1338 161264b8a90f40a937a88db2441db87f 464 Hamap MF_00028 Cobyric acid synthase [cobQ]. 1 464 141.549 T 31-10-2018 IPR004459 Cobyric acid synthase CobQ GO:0003824|GO:0009236 AF_1338 161264b8a90f40a937a88db2441db87f 464 Gene3D G3DSA:3.40.50.300 3 238 2.5E-49 T 31-10-2018 AF_2016 4cba0ade6a65c1c8eb170cbe7370faa9 307 Pfam PF01370 NAD dependent epimerase/dehydratase family 3 224 3.5E-29 T 31-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AF_2016 4cba0ade6a65c1c8eb170cbe7370faa9 307 Gene3D G3DSA:3.40.50.720 1 304 2.9E-65 T 31-10-2018 AF_2016 4cba0ade6a65c1c8eb170cbe7370faa9 307 SUPERFAMILY SSF51735 1 302 1.43E-53 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_2415 cb7441f3db4535e5a0b6aa2992f25c5c 303 Gene3D G3DSA:3.40.47.10 1 295 2.0E-73 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_2415 cb7441f3db4535e5a0b6aa2992f25c5c 303 TIGRFAM TIGR00748 HMG_CoA_syn_Arc: putative hydroxymethylglutaryl-CoA synthase 1 292 3.8E-146 T 31-10-2018 IPR004656 Putative condensing enzyme FabH-related AF_2415 cb7441f3db4535e5a0b6aa2992f25c5c 303 SUPERFAMILY SSF53901 2 167 3.92E-40 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_2415 cb7441f3db4535e5a0b6aa2992f25c5c 303 Pfam PF08541 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal 217 293 4.0E-6 T 31-10-2018 IPR013747 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III, C-terminal KEGG: 00061+2.3.1.180|MetaCyc: PWY-4381 AF_2415 cb7441f3db4535e5a0b6aa2992f25c5c 303 SUPERFAMILY SSF53901 168 292 6.62E-34 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_1176 39869aede6ee693df5927be2d685b0db 248 SUPERFAMILY SSF160104 5 248 7.19E-40 T 31-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 AF_1176 39869aede6ee693df5927be2d685b0db 248 Gene3D G3DSA:2.40.400.10 6 248 4.8E-45 T 31-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 AF_1176 39869aede6ee693df5927be2d685b0db 248 Pfam PF06314 Acetoacetate decarboxylase (ADC) 15 248 3.1E-51 T 31-10-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 AF_2428 e62f92f86aa8bef8846619430dcda9f3 262 Pfam PF01261 Xylose isomerase-like TIM barrel 21 209 6.0E-14 T 31-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AF_2428 e62f92f86aa8bef8846619430dcda9f3 262 Gene3D G3DSA:3.20.20.150 1 258 1.8E-35 T 31-10-2018 AF_2428 e62f92f86aa8bef8846619430dcda9f3 262 SUPERFAMILY SSF51658 1 236 1.37E-32 T 31-10-2018 IPR036237 Xylose isomerase-like superfamily AF_2225 dc7c112d5ee14cd98b6982a9f9086ef3 250 Pfam PF01557 Fumarylacetoacetate (FAA) hydrolase family 45 238 1.5E-70 T 31-10-2018 IPR011234 Fumarylacetoacetase-like, C-terminal GO:0003824 AF_2225 dc7c112d5ee14cd98b6982a9f9086ef3 250 Gene3D G3DSA:3.90.850.10 23 242 3.0E-87 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AF_2225 dc7c112d5ee14cd98b6982a9f9086ef3 250 SUPERFAMILY SSF56529 38 240 1.22E-81 T 31-10-2018 IPR036663 Fumarylacetoacetase-like, C-terminal domain superfamily GO:0003824 AF_0384 7ea9f63bee5d29a69153089e2212bd88 313 Pfam PF04473 Transglutaminase-like domain 51 198 1.4E-52 T 31-10-2018 IPR007562 Transglutaminase-like domain AF_0384 7ea9f63bee5d29a69153089e2212bd88 313 Gene3D G3DSA:3.10.620.30 41 176 7.5E-8 T 31-10-2018 AF_0384 7ea9f63bee5d29a69153089e2212bd88 313 SUPERFAMILY SSF54001 105 171 1.0E-4 T 31-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AF_1362 c863c02775a0cdf0c1bbd09c7fa1c1e0 340 Gene3D G3DSA:2.160.10.10 2 119 7.7E-10 T 31-10-2018 AF_1362 c863c02775a0cdf0c1bbd09c7fa1c1e0 340 SUPERFAMILY SSF51161 16 105 3.01E-11 T 31-10-2018 IPR011004 Trimeric LpxA-like superfamily AF_1596 4327fa2e8b2886b37a5065bb80695e13 95 Gene3D G3DSA:1.10.10.10 24 94 1.2E-11 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1596 4327fa2e8b2886b37a5065bb80695e13 95 SUPERFAMILY SSF46785 34 88 2.2E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1596 4327fa2e8b2886b37a5065bb80695e13 95 Pfam PF13601 Winged helix DNA-binding domain 38 88 3.1E-7 T 31-10-2018 IPR027395 Winged helix DNA-binding domain AF_0914 d3e2368576fe294a856ef1e26708f96f 101 SUPERFAMILY SSF55159 2 98 2.88E-29 T 31-10-2018 IPR036877 SUI1 domain superfamily GO:0003743|GO:0006413 AF_0914 d3e2368576fe294a856ef1e26708f96f 101 TIGRFAM TIGR01158 SUI1_rel: putative translation initiation factor SUI1 3 100 4.0E-39 T 31-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 AF_0914 d3e2368576fe294a856ef1e26708f96f 101 Gene3D G3DSA:3.30.780.10 24 101 2.6E-28 T 31-10-2018 AF_0914 d3e2368576fe294a856ef1e26708f96f 101 Pfam PF01253 Translation initiation factor SUI1 24 94 2.2E-21 T 31-10-2018 IPR001950 SUI1 domain GO:0003743|GO:0006413 AF_0914 d3e2368576fe294a856ef1e26708f96f 101 Hamap MF_00604 Protein translation factor SUI1 homolog. 6 97 29.761 T 31-10-2018 IPR022851 Translation factor SUI1 homolog, archaea AF_0914 d3e2368576fe294a856ef1e26708f96f 101 PIRSF PIRSF037511 1 101 8.3E-30 T 31-10-2018 IPR005872 Archaeal/bacterial translation initiation factor SUI1 GO:0003743 AF_1794 0e5853aad869a37b8a5c7bf5495c6865 392 Gene3D G3DSA:3.40.50.720 4 381 2.7E-157 T 31-10-2018 AF_1794 0e5853aad869a37b8a5c7bf5495c6865 392 SUPERFAMILY SSF51735 1 389 6.22E-70 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1794 0e5853aad869a37b8a5c7bf5495c6865 392 Pfam PF01658 Myo-inositol-1-phosphate synthase 229 332 2.6E-24 T 31-10-2018 IPR013021 Myo-inositol-1-phosphate synthase, GAPDH-like KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 AF_1794 0e5853aad869a37b8a5c7bf5495c6865 392 PIRSF PIRSF015578 1 392 8.7E-117 T 31-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 AF_1794 0e5853aad869a37b8a5c7bf5495c6865 392 Gene3D G3DSA:3.30.360.10 229 329 2.7E-157 T 31-10-2018 AF_1794 0e5853aad869a37b8a5c7bf5495c6865 392 SUPERFAMILY SSF55347 228 332 4.45E-32 T 31-10-2018 AF_1794 0e5853aad869a37b8a5c7bf5495c6865 392 Pfam PF07994 Myo-inositol-1-phosphate synthase 1 381 5.7E-44 T 31-10-2018 IPR002587 Myo-inositol-1-phosphate synthase GO:0004512|GO:0006021|GO:0008654 KEGG: 00521+5.5.1.4|KEGG: 00562+5.5.1.4|MetaCyc: PWY-2301|MetaCyc: PWY-4661|MetaCyc: PWY-6372|MetaCyc: PWY-6580|MetaCyc: PWY-6664|Reactome: R-HSA-1855183 AF_0057 c41fbbbbacdd9897084d1a31cb4f364b 83 Pfam PF01780 Ribosomal L37ae protein family 3 82 6.6E-32 T 31-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_0057 c41fbbbbacdd9897084d1a31cb4f364b 83 TIGRFAM TIGR00280 eL43_euk_arch: ribosomal protein eL43 1 82 1.6E-41 T 31-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_0057 c41fbbbbacdd9897084d1a31cb4f364b 83 Gene3D G3DSA:2.20.25.30 9 83 1.5E-29 T 31-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_0057 c41fbbbbacdd9897084d1a31cb4f364b 83 SUPERFAMILY SSF57829 10 80 8.55E-27 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AF_0057 c41fbbbbacdd9897084d1a31cb4f364b 83 Hamap MF_00327 50S ribosomal protein L37Ae [rpl37ae]. 3 71 23.013 T 31-10-2018 IPR002674 Ribosomal protein L37ae GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_0229 ac09cb84c1e0e129ab3c6cc0a669f3ef 323 PIRSF PIRSF006655 53 323 6.5E-120 T 31-10-2018 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 AF_0229 ac09cb84c1e0e129ab3c6cc0a669f3ef 323 PIRSF PIRSF006655 1 66 3.1E-5 T 31-10-2018 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 AF_0229 ac09cb84c1e0e129ab3c6cc0a669f3ef 323 Hamap MF_01244 3-dehydroquinate synthase [aroB']. 1 323 38.181 T 31-10-2018 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 AF_0229 ac09cb84c1e0e129ab3c6cc0a669f3ef 323 ProDom PD017907 3-DEHYDROQUINATE UPF0245 SYNTHASE LYASE PREDICTED SYNTHASE-LIKE ALTERNATIVE T19N8 MM1272 MK1408 16 322 1.0E-166 T 31-10-2018 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 AF_0229 ac09cb84c1e0e129ab3c6cc0a669f3ef 323 Pfam PF01959 3-dehydroquinate synthase (EC 4.6.1.3) 55 323 2.0E-113 T 31-10-2018 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 AF_0229 ac09cb84c1e0e129ab3c6cc0a669f3ef 323 Pfam PF01959 3-dehydroquinate synthase (EC 4.6.1.3) 2 70 2.0E-6 T 31-10-2018 IPR002812 3-dehydroquinate synthase GO:0003856|GO:0009073|GO:0016491|GO:0055114 KEGG: 00400+1.4.1.24|MetaCyc: PWY-6160 AF_0641 116ce00edd11a29a0ea9bd9397a9c35a 52 Pfam PF09853 Putative transposon-encoded protein (DUF2080) 4 52 2.3E-18 T 31-10-2018 IPR019205 Protein of unknown function DUF2080, transposon-encoded AF_2091 116ce00edd11a29a0ea9bd9397a9c35a 52 Pfam PF09853 Putative transposon-encoded protein (DUF2080) 4 52 2.3E-18 T 31-10-2018 IPR019205 Protein of unknown function DUF2080, transposon-encoded AF_0564 8a264c6c010e5a031eeddd6ba94343d5 382 PIRSF PIRSF005572 1 377 5.6E-128 T 31-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 AF_0564 8a264c6c010e5a031eeddd6ba94343d5 382 Gene3D G3DSA:3.40.640.10 13 253 8.0E-154 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AF_0564 8a264c6c010e5a031eeddd6ba94343d5 382 Pfam PF00266 Aminotransferase class-V 3 362 4.8E-80 T 31-10-2018 IPR000192 Aminotransferase class V domain AF_0564 8a264c6c010e5a031eeddd6ba94343d5 382 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 1 382 49.58 T 31-10-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 AF_0564 8a264c6c010e5a031eeddd6ba94343d5 382 SUPERFAMILY SSF53383 2 372 2.92E-99 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AF_0564 8a264c6c010e5a031eeddd6ba94343d5 382 Gene3D G3DSA:3.90.1150.10 3 363 8.0E-154 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AF_0544 3e3ef6dbccc5fd10a27043adf3e36fc3 521 Pfam PF02754 Cysteine-rich domain 384 483 8.4E-7 T 31-10-2018 IPR004017 Cysteine-rich domain AF_0544 3e3ef6dbccc5fd10a27043adf3e36fc3 521 SUPERFAMILY SSF46548 100 195 1.12E-14 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_0544 3e3ef6dbccc5fd10a27043adf3e36fc3 521 Gene3D G3DSA:1.10.1060.10 86 204 2.9E-9 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_0544 3e3ef6dbccc5fd10a27043adf3e36fc3 521 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 107 118 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0544 3e3ef6dbccc5fd10a27043adf3e36fc3 521 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 169 180 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0544 3e3ef6dbccc5fd10a27043adf3e36fc3 521 Pfam PF13183 4Fe-4S dicluster domain 104 183 8.2E-10 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0928 2423c5f1c7ca23c0dd45cdf2e80a2c73 210 Gene3D G3DSA:1.10.260.80 32 82 1.2E-37 T 31-10-2018 AF_0928 2423c5f1c7ca23c0dd45cdf2e80a2c73 210 TIGRFAM TIGR01549 HAD-SF-IA-v1: HAD hydrolase, family IA, variant 1 22 170 8.9E-12 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AF_0928 2423c5f1c7ca23c0dd45cdf2e80a2c73 210 SUPERFAMILY SSF56784 19 206 5.7E-35 T 31-10-2018 IPR036412 HAD-like superfamily AF_0928 2423c5f1c7ca23c0dd45cdf2e80a2c73 210 Pfam PF13419 Haloacid dehalogenase-like hydrolase 38 175 3.0E-15 T 31-10-2018 AF_0928 2423c5f1c7ca23c0dd45cdf2e80a2c73 210 TIGRFAM TIGR01509 HAD-SF-IA-v3: HAD hydrolase, family IA, variant 3 22 175 3.3E-10 T 31-10-2018 IPR006439 HAD hydrolase, subfamily IA GO:0016787 AF_0928 2423c5f1c7ca23c0dd45cdf2e80a2c73 210 Gene3D G3DSA:3.40.50.1000 23 182 1.2E-37 T 31-10-2018 IPR023214 HAD superfamily AF_1791 e0ed9e6acd43305c0bd52438ae6d0602 189 Pfam PF00717 Peptidase S24-like 41 104 1.4E-5 T 31-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AF_1791 e0ed9e6acd43305c0bd52438ae6d0602 189 SUPERFAMILY SSF51306 34 186 1.73E-17 T 31-10-2018 IPR036286 LexA/Signal peptidase-like superfamily AF_1071 8c4068acdf12b695d568038047488249 92 Gene3D G3DSA:3.30.420.10 5 42 2.4E-5 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AF_1551 f6a1f0878a3ab9f1fa6fd4565686736b 292 Gene3D G3DSA:1.10.600.10 1 291 3.4E-81 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily AF_1551 f6a1f0878a3ab9f1fa6fd4565686736b 292 SUPERFAMILY SSF48576 13 278 2.88E-59 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily AF_1551 f6a1f0878a3ab9f1fa6fd4565686736b 292 Pfam PF00348 Polyprenyl synthetase 28 211 6.6E-47 T 31-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 AF_0400 af2cf596367e67b4d6a871673ef845a4 551 Gene3D G3DSA:3.40.250.10 455 551 8.6E-24 T 31-10-2018 IPR036873 Rhodanese-like domain superfamily AF_0400 af2cf596367e67b4d6a871673ef845a4 551 SUPERFAMILY SSF52821 448 550 7.33E-24 T 31-10-2018 IPR036873 Rhodanese-like domain superfamily AF_0400 af2cf596367e67b4d6a871673ef845a4 551 SMART SM00450 459 551 3.5E-19 T 31-10-2018 IPR001763 Rhodanese-like domain AF_0400 af2cf596367e67b4d6a871673ef845a4 551 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 240 256 5.3E-28 T 31-10-2018 AF_0400 af2cf596367e67b4d6a871673ef845a4 551 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 5.3E-28 T 31-10-2018 AF_0400 af2cf596367e67b4d6a871673ef845a4 551 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 109 127 5.3E-28 T 31-10-2018 AF_0400 af2cf596367e67b4d6a871673ef845a4 551 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 155 173 5.3E-28 T 31-10-2018 AF_0400 af2cf596367e67b4d6a871673ef845a4 551 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 267 289 5.3E-28 T 31-10-2018 AF_0400 af2cf596367e67b4d6a871673ef845a4 551 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 334 438 5.5E-18 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AF_0400 af2cf596367e67b4d6a871673ef845a4 551 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 5.5E-19 T 31-10-2018 AF_0400 af2cf596367e67b4d6a871673ef845a4 551 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 241 255 5.5E-19 T 31-10-2018 AF_0400 af2cf596367e67b4d6a871673ef845a4 551 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 282 289 5.5E-19 T 31-10-2018 AF_0400 af2cf596367e67b4d6a871673ef845a4 551 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 155 180 5.5E-19 T 31-10-2018 AF_0400 af2cf596367e67b4d6a871673ef845a4 551 Gene3D G3DSA:3.50.50.60 118 444 1.8E-167 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0400 af2cf596367e67b4d6a871673ef845a4 551 Gene3D G3DSA:3.50.50.60 3 345 1.8E-167 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0400 af2cf596367e67b4d6a871673ef845a4 551 SUPERFAMILY SSF51905 1 320 4.04E-51 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0400 af2cf596367e67b4d6a871673ef845a4 551 Pfam PF00581 Rhodanese-like domain 463 550 2.7E-13 T 31-10-2018 IPR001763 Rhodanese-like domain AF_0400 af2cf596367e67b4d6a871673ef845a4 551 SUPERFAMILY SSF55424 328 452 6.01E-34 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AF_0400 af2cf596367e67b4d6a871673ef845a4 551 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 289 6.3E-67 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AF_2067 8319bc9debafad7443421e15e4447e70 50 Gene3D G3DSA:1.10.1620.10 1 49 1.2E-18 T 31-10-2018 IPR023626 Ribosomal protein L39e domain superfamily AF_2067 8319bc9debafad7443421e15e4447e70 50 Pfam PF00832 Ribosomal L39 protein 8 49 1.2E-19 T 31-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_2067 8319bc9debafad7443421e15e4447e70 50 SUPERFAMILY SSF48662 2 50 6.67E-19 T 31-10-2018 IPR023626 Ribosomal protein L39e domain superfamily AF_2067 8319bc9debafad7443421e15e4447e70 50 Hamap MF_00629 50S ribosomal protein L39e [rpl39e]. 1 50 16.58 T 31-10-2018 IPR000077 Ribosomal protein L39e GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_2067 8319bc9debafad7443421e15e4447e70 50 ProSitePatterns PS00051 Ribosomal protein L39e signature. 29 45 - T 31-10-2018 IPR020083 Ribosomal protein L39e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0246 8dc0fbba0cfedf40bb4f764a712a3176 639 SUPERFAMILY SSF52540 16 172 1.48E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0246 8dc0fbba0cfedf40bb4f764a712a3176 639 Gene3D G3DSA:3.40.50.300 13 192 4.4E-40 T 31-10-2018 AF_0246 8dc0fbba0cfedf40bb4f764a712a3176 639 Pfam PF02421 Ferrous iron transport protein B 16 164 1.6E-48 T 31-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 AF_0246 8dc0fbba0cfedf40bb4f764a712a3176 639 Pfam PF07670 Nucleoside recognition 357 447 5.3E-11 T 31-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 AF_0246 8dc0fbba0cfedf40bb4f764a712a3176 639 Pfam PF07670 Nucleoside recognition 511 611 1.7E-9 T 31-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 AF_0246 8dc0fbba0cfedf40bb4f764a712a3176 639 Pfam PF07664 Ferrous iron transport protein B C terminus 454 505 6.3E-10 T 31-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 AF_0246 8dc0fbba0cfedf40bb4f764a712a3176 639 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 17 37 1.9E-6 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 AF_0246 8dc0fbba0cfedf40bb4f764a712a3176 639 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 38 56 1.9E-6 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 AF_0246 8dc0fbba0cfedf40bb4f764a712a3176 639 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 13 127 3.4E-15 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AF_0246 8dc0fbba0cfedf40bb4f764a712a3176 639 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 21 608 5.0E-179 T 31-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 AF_1146 0940787aa342b3b4cfbc188ccaea990d 407 PRINTS PR00477 Phosphoglycerate kinase family signature 374 391 4.7E-59 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1146 0940787aa342b3b4cfbc188ccaea990d 407 PRINTS PR00477 Phosphoglycerate kinase family signature 13 29 4.7E-59 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1146 0940787aa342b3b4cfbc188ccaea990d 407 PRINTS PR00477 Phosphoglycerate kinase family signature 319 344 4.7E-59 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1146 0940787aa342b3b4cfbc188ccaea990d 407 PRINTS PR00477 Phosphoglycerate kinase family signature 108 123 4.7E-59 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1146 0940787aa342b3b4cfbc188ccaea990d 407 PRINTS PR00477 Phosphoglycerate kinase family signature 351 362 4.7E-59 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1146 0940787aa342b3b4cfbc188ccaea990d 407 PRINTS PR00477 Phosphoglycerate kinase family signature 34 56 4.7E-59 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1146 0940787aa342b3b4cfbc188ccaea990d 407 PRINTS PR00477 Phosphoglycerate kinase family signature 195 214 4.7E-59 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1146 0940787aa342b3b4cfbc188ccaea990d 407 PRINTS PR00477 Phosphoglycerate kinase family signature 143 165 4.7E-59 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1146 0940787aa342b3b4cfbc188ccaea990d 407 PRINTS PR00477 Phosphoglycerate kinase family signature 173 195 4.7E-59 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1146 0940787aa342b3b4cfbc188ccaea990d 407 PIRSF PIRSF000724 1 405 4.3E-129 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1146 0940787aa342b3b4cfbc188ccaea990d 407 SUPERFAMILY SSF53748 5 397 1.77E-108 T 31-10-2018 IPR036043 Phosphoglycerate kinase superfamily GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1146 0940787aa342b3b4cfbc188ccaea990d 407 Hamap MF_00145 Phosphoglycerate kinase [pgk]. 8 398 33.877 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1146 0940787aa342b3b4cfbc188ccaea990d 407 ProSitePatterns PS00111 Phosphoglycerate kinase signature. 18 28 - T 31-10-2018 IPR015911 Phosphoglycerate kinase, conserved site GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1146 0940787aa342b3b4cfbc188ccaea990d 407 Gene3D G3DSA:3.40.50.1260 15 394 5.4E-114 T 31-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1146 0940787aa342b3b4cfbc188ccaea990d 407 Pfam PF00162 Phosphoglycerate kinase 10 387 1.4E-104 T 31-10-2018 IPR001576 Phosphoglycerate kinase GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1146 0940787aa342b3b4cfbc188ccaea990d 407 Gene3D G3DSA:3.40.50.1260 191 388 5.4E-114 T 31-10-2018 IPR015824 Phosphoglycerate kinase, N-terminal GO:0004618|GO:0006096 KEGG: 00010+2.7.2.3|KEGG: 00710+2.7.2.3|MetaCyc: PWY-1042|MetaCyc: PWY-5484|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_0942 ad6c561a4841035f29e7a2db137daf61 261 SUPERFAMILY SSF64167 1 258 5.62E-80 T 31-10-2018 AF_0942 ad6c561a4841035f29e7a2db137daf61 261 Gene3D G3DSA:3.40.1210.10 1 256 8.3E-86 T 31-10-2018 IPR036523 SurE-like phosphatase/nucleotidase superfamily GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 AF_0942 ad6c561a4841035f29e7a2db137daf61 261 Hamap MF_00060 5'/3'-nucleotidase SurE [surE]. 1 259 37.137 T 31-10-2018 IPR030048 Survival protein SurE GO:0008252 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 AF_0942 ad6c561a4841035f29e7a2db137daf61 261 TIGRFAM TIGR00087 surE: 5'/3'-nucleotidase SurE 1 242 3.8E-90 T 31-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 AF_0942 ad6c561a4841035f29e7a2db137daf61 261 Pfam PF01975 Survival protein SurE 3 193 2.7E-52 T 31-10-2018 IPR002828 Survival protein SurE-like phosphatase/nucleotidase GO:0016787 KEGG: 00230+3.1.3.5|KEGG: 00240+3.1.3.5|KEGG: 00760+3.1.3.5|MetaCyc: PWY-5381|MetaCyc: PWY-5695|MetaCyc: PWY-6596|MetaCyc: PWY-6606|MetaCyc: PWY-6607|MetaCyc: PWY-6608|MetaCyc: PWY-7185|MetaCyc: PWY-7821 AF_1818 c16ad24c570de6be914d47de26eb3cd8 478 Gene3D G3DSA:2.60.40.10 345 449 5.1E-7 T 31-10-2018 IPR013783 Immunoglobulin-like fold AF_1818 c16ad24c570de6be914d47de26eb3cd8 478 Pfam PF07705 CARDB 351 427 7.1E-6 T 31-10-2018 IPR011635 CARDB domain AF_1970 45417fff0f0d40109079aa92c3a6b755 313 Pfam PF13424 Tetratricopeptide repeat 225 299 1.7E-12 T 31-10-2018 AF_1970 45417fff0f0d40109079aa92c3a6b755 313 Pfam PF13424 Tetratricopeptide repeat 141 213 3.0E-13 T 31-10-2018 AF_1970 45417fff0f0d40109079aa92c3a6b755 313 SMART SM00028 141 174 0.25 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AF_1970 45417fff0f0d40109079aa92c3a6b755 313 SMART SM00028 226 259 0.054 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AF_1970 45417fff0f0d40109079aa92c3a6b755 313 SMART SM00028 271 304 0.019 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AF_1970 45417fff0f0d40109079aa92c3a6b755 313 SMART SM00028 181 214 0.041 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AF_1970 45417fff0f0d40109079aa92c3a6b755 313 SMART SM00028 101 134 28.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AF_1970 45417fff0f0d40109079aa92c3a6b755 313 Gene3D G3DSA:1.25.40.10 219 312 1.1E-14 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AF_1970 45417fff0f0d40109079aa92c3a6b755 313 SUPERFAMILY SSF48452 105 309 1.71E-25 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AF_1970 45417fff0f0d40109079aa92c3a6b755 313 Gene3D G3DSA:1.25.40.10 83 218 1.6E-20 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AF_1509 3140efc1dcdb69df9ad07bc38808b10f 262 SMART SM00849 32 225 4.2E-21 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_1509 3140efc1dcdb69df9ad07bc38808b10f 262 SUPERFAMILY SSF56281 12 256 6.42E-34 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_1509 3140efc1dcdb69df9ad07bc38808b10f 262 Gene3D G3DSA:3.60.15.10 1 215 2.7E-50 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_1509 3140efc1dcdb69df9ad07bc38808b10f 262 Pfam PF00753 Metallo-beta-lactamase superfamily 31 235 4.6E-24 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 SMART SM01072 109 171 4.2E-20 T 31-10-2018 IPR004201 CDC48, domain 2 AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 ProSitePatterns PS00674 AAA-protein family signature. 319 337 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 10 93 4.6E-31 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 SMART SM00382 488 625 1.4E-24 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 SMART SM00382 215 351 1.3E-25 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 SUPERFAMILY SSF54585 95 184 4.9E-21 T 31-10-2018 IPR029067 CDC48 domain 2-like superfamily AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 Gene3D G3DSA:1.10.8.60 350 445 1.4E-35 T 31-10-2018 AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 SMART SM01073 10 94 2.0E-40 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 Gene3D G3DSA:3.40.50.300 450 722 9.5E-113 T 31-10-2018 AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 Gene3D G3DSA:3.10.330.10 114 181 1.8E-6 T 31-10-2018 AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 Pfam PF02933 Cell division protein 48 (CDC48), domain 2 112 171 3.5E-18 T 31-10-2018 IPR004201 CDC48, domain 2 AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 SUPERFAMILY SSF52540 177 444 1.54E-78 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 TIGRFAM TIGR01243 CDC48: AAA family ATPase, CDC48 subfamily 9 730 0.0 T 31-10-2018 IPR005938 AAA ATPase, CDC48 family GO:0016787 Reactome: R-HSA-110320|Reactome: R-HSA-3371511|Reactome: R-HSA-382556|Reactome: R-HSA-532668|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5678895|Reactome: R-HSA-5689877|Reactome: R-HSA-5689896|Reactome: R-HSA-6798695|Reactome: R-HSA-8866654|Reactome: R-HSA-8876725 AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 Gene3D G3DSA:3.40.50.300 182 348 2.0E-69 T 31-10-2018 AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 219 348 1.1E-50 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 492 622 8.6E-50 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 Gene3D G3DSA:2.40.40.20 3 94 4.7E-35 T 31-10-2018 AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 Pfam PF09336 Vps4 C terminal oligomerisation domain 690 728 3.4E-6 T 31-10-2018 IPR015415 Vps4 oligomerisation, C-terminal AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 ProSitePatterns PS00674 AAA-protein family signature. 593 611 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 SUPERFAMILY SSF50692 5 92 3.25E-30 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 SUPERFAMILY SSF52540 450 726 7.65E-82 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1297 5b6a074a838cf56c09e052fc8550ddda 733 Gene3D G3DSA:1.10.8.60 624 709 9.5E-113 T 31-10-2018 AF_1219 e2942551262ab38c8f77667e94e07213 251 TIGRFAM TIGR00055 uppS: di-trans,poly-cis-decaprenylcistransferase 20 247 1.0E-80 T 31-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AF_1219 e2942551262ab38c8f77667e94e07213 251 SUPERFAMILY SSF64005 18 246 3.53E-80 T 31-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 AF_1219 e2942551262ab38c8f77667e94e07213 251 Hamap MF_01139 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) [uppS]. 20 251 37.388 T 31-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AF_1219 e2942551262ab38c8f77667e94e07213 251 Gene3D G3DSA:3.40.1180.10 3 245 2.9E-92 T 31-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 AF_1219 e2942551262ab38c8f77667e94e07213 251 ProSitePatterns PS01066 Undecaprenyl pyrophosphate synthase family signature. 196 213 - T 31-10-2018 IPR018520 Di-trans-poly-cis-decaprenylcistransferase-like, conserved site GO:0016765 Reactome: R-HSA-446199|Reactome: R-HSA-4755609 AF_1219 e2942551262ab38c8f77667e94e07213 251 Pfam PF01255 Putative undecaprenyl diphosphate synthase 27 246 6.2E-78 T 31-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AF_0219 ab59da1b1b7a65af0cb728e437c49521 503 Pfam PF00682 HMGL-like 8 265 1.8E-89 T 31-10-2018 IPR000891 Pyruvate carboxyltransferase GO:0003824 AF_0219 ab59da1b1b7a65af0cb728e437c49521 503 ProSitePatterns PS00816 Alpha-isopropylmalate and homocitrate synthases signature 2. 194 207 - T 31-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AF_0219 ab59da1b1b7a65af0cb728e437c49521 503 ProSitePatterns PS00815 Alpha-isopropylmalate and homocitrate synthases signature 1. 15 31 - T 31-10-2018 IPR002034 Alpha-isopropylmalate/homocitrate synthase, conserved site GO:0019752|GO:0046912 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AF_0219 ab59da1b1b7a65af0cb728e437c49521 503 SMART SM00917 362 496 4.5E-29 T 31-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AF_0219 ab59da1b1b7a65af0cb728e437c49521 503 Gene3D G3DSA:3.20.20.70 4 268 2.0E-99 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0219 ab59da1b1b7a65af0cb728e437c49521 503 SUPERFAMILY SSF110921 391 495 2.75E-21 T 31-10-2018 IPR036230 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain superfamily KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AF_0219 ab59da1b1b7a65af0cb728e437c49521 503 TIGRFAM TIGR02090 LEU1_arch: isopropylmalate/citramalate/homocitrate synthases 8 371 1.6E-155 T 31-10-2018 IPR011830 Isopropylmalate/citramalate/homocitrate synthase GO:0019752|GO:0046912 AF_0219 ab59da1b1b7a65af0cb728e437c49521 503 SUPERFAMILY SSF51569 4 283 2.56E-97 T 31-10-2018 AF_0219 ab59da1b1b7a65af0cb728e437c49521 503 Gene3D G3DSA:1.10.238.260 272 389 1.6E-33 T 31-10-2018 AF_0219 ab59da1b1b7a65af0cb728e437c49521 503 Pfam PF08502 LeuA allosteric (dimerisation) domain 363 496 2.2E-34 T 31-10-2018 IPR013709 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain GO:0003852|GO:0009098 KEGG: 00290+2.3.3.13|KEGG: 00620+2.3.3.13|MetaCyc: PWY-6871 AF_0219 ab59da1b1b7a65af0cb728e437c49521 503 Gene3D G3DSA:3.30.160.270 390 497 4.6E-12 T 31-10-2018 AF_0958 7ce8e7f8b2561828cc761005e5833fa4 221 ProSitePatterns PS00211 ABC transporters family signature. 126 140 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_0958 7ce8e7f8b2561828cc761005e5833fa4 221 SMART SM00382 29 202 2.5E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0958 7ce8e7f8b2561828cc761005e5833fa4 221 Pfam PF00005 ABC transporter 20 153 1.6E-26 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0958 7ce8e7f8b2561828cc761005e5833fa4 221 SUPERFAMILY SSF52540 4 210 1.3E-46 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0958 7ce8e7f8b2561828cc761005e5833fa4 221 Gene3D G3DSA:3.40.50.300 1 219 1.6E-46 T 31-10-2018 AF_1894 e1e389bd2735c53969945da704207718 728 Pfam PF03144 Elongation factor Tu domain 2 304 370 4.7E-15 T 31-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AF_1894 e1e389bd2735c53969945da704207718 728 Gene3D G3DSA:3.40.50.300 5 219 1.2E-74 T 31-10-2018 AF_1894 e1e389bd2735c53969945da704207718 728 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 21 157 2.1E-24 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AF_1894 e1e389bd2735c53969945da704207718 728 Pfam PF03764 Elongation factor G, domain IV 508 616 2.3E-28 T 31-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AF_1894 e1e389bd2735c53969945da704207718 728 Pfam PF00009 Elongation factor Tu GTP binding domain 20 256 6.5E-66 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_1894 e1e389bd2735c53969945da704207718 728 SUPERFAMILY SSF54980 621 716 1.26E-24 T 31-10-2018 IPR035647 EF-G domain III/V-like AF_1894 e1e389bd2735c53969945da704207718 728 Pfam PF00679 Elongation factor G C-terminus 619 703 6.5E-24 T 31-10-2018 IPR000640 Elongation factor EFG, domain V-like AF_1894 e1e389bd2735c53969945da704207718 728 Hamap MF_00054_A Elongation factor G [fusA]. 1 722 43.298 T 31-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 AF_1894 e1e389bd2735c53969945da704207718 728 SUPERFAMILY SSF54980 386 462 1.33E-23 T 31-10-2018 IPR035647 EF-G domain III/V-like AF_1894 e1e389bd2735c53969945da704207718 728 Gene3D G3DSA:3.30.230.10 471 718 5.9E-78 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AF_1894 e1e389bd2735c53969945da704207718 728 Gene3D G3DSA:3.30.70.240 465 715 5.9E-78 T 31-10-2018 AF_1894 e1e389bd2735c53969945da704207718 728 Pfam PF14492 Elongation Factor G, domain II 386 458 8.9E-27 T 31-10-2018 AF_1894 e1e389bd2735c53969945da704207718 728 SUPERFAMILY SSF52540 7 260 4.53E-73 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1894 e1e389bd2735c53969945da704207718 728 ProSitePatterns PS00301 Translational (tr)-type guanine nucleotide-binding (G) domain signature. 59 74 - T 31-10-2018 IPR031157 Tr-type G domain, conserved site AF_1894 e1e389bd2735c53969945da704207718 728 Gene3D G3DSA:2.40.30.10 257 385 2.1E-28 T 31-10-2018 AF_1894 e1e389bd2735c53969945da704207718 728 SMART SM00889 504 616 1.9E-21 T 31-10-2018 IPR005517 Translation elongation factor EFG/EF2, domain IV GO:0005525 AF_1894 e1e389bd2735c53969945da704207718 728 PRINTS PR00315 GTP-binding elongation factor signature 22 35 2.1E-16 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_1894 e1e389bd2735c53969945da704207718 728 PRINTS PR00315 GTP-binding elongation factor signature 142 151 2.1E-16 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_1894 e1e389bd2735c53969945da704207718 728 PRINTS PR00315 GTP-binding elongation factor signature 66 74 2.1E-16 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_1894 e1e389bd2735c53969945da704207718 728 PRINTS PR00315 GTP-binding elongation factor signature 90 100 2.1E-16 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_1894 e1e389bd2735c53969945da704207718 728 PRINTS PR00315 GTP-binding elongation factor signature 106 117 2.1E-16 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_1894 e1e389bd2735c53969945da704207718 728 SUPERFAMILY SSF50447 256 382 2.01E-32 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AF_1894 e1e389bd2735c53969945da704207718 728 SMART SM00838 618 705 9.3E-47 T 31-10-2018 IPR000640 Elongation factor EFG, domain V-like AF_1894 e1e389bd2735c53969945da704207718 728 Gene3D G3DSA:3.30.70.870 387 462 5.1E-27 T 31-10-2018 AF_1894 e1e389bd2735c53969945da704207718 728 TIGRFAM TIGR00490 aEF-2: translation elongation factor aEF-2 2 718 0.0 T 31-10-2018 IPR004543 Translation elongation factor EFG/EF2, archaeal GO:0003746|GO:0005525|GO:0005737|GO:0006414 AF_1894 e1e389bd2735c53969945da704207718 728 SUPERFAMILY SSF54211 462 620 1.64E-48 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AF_1232 5f66f5f7d8e92358815d157ef8c2905d 231 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 6 71 1.8E-22 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal AF_1232 5f66f5f7d8e92358815d157ef8c2905d 231 Gene3D G3DSA:1.10.10.10 1 98 2.3E-25 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1232 5f66f5f7d8e92358815d157ef8c2905d 231 SUPERFAMILY SSF46785 2 93 2.27E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1162 aa9f35934db2aa7228432357b2c7c56a 75 Gene3D G3DSA:1.20.120.610 2 74 3.4E-15 T 31-10-2018 AF_1162 aa9f35934db2aa7228432357b2c7c56a 75 SUPERFAMILY SSF81333 5 74 5.62E-14 T 31-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily AF_1162 aa9f35934db2aa7228432357b2c7c56a 75 Pfam PF00137 ATP synthase subunit C 13 71 8.3E-14 T 31-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 AF_1160 aa9f35934db2aa7228432357b2c7c56a 75 Gene3D G3DSA:1.20.120.610 2 74 3.4E-15 T 31-10-2018 AF_1160 aa9f35934db2aa7228432357b2c7c56a 75 SUPERFAMILY SSF81333 5 74 5.62E-14 T 31-10-2018 IPR035921 F/V-ATP synthase subunit C superfamily AF_1160 aa9f35934db2aa7228432357b2c7c56a 75 Pfam PF00137 ATP synthase subunit C 13 71 8.3E-14 T 31-10-2018 IPR002379 V-ATPase proteolipid subunit C-like domain GO:0015078|GO:0015991|GO:0033177 AF_0647 4a215462b44fdc1e9ca0bd4ef6a4de96 412 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 30 405 1.7E-110 T 31-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AF_0647 4a215462b44fdc1e9ca0bd4ef6a4de96 412 Gene3D G3DSA:3.40.718.10 1 412 3.5E-189 T 31-10-2018 AF_0647 4a215462b44fdc1e9ca0bd4ef6a4de96 412 SUPERFAMILY SSF53659 3 409 3.26E-143 T 31-10-2018 AF_0647 4a215462b44fdc1e9ca0bd4ef6a4de96 412 TIGRFAM TIGR00183 prok_nadp_idh: isocitrate dehydrogenase, NADP-dependent 2 410 3.5E-218 T 31-10-2018 IPR004439 Isocitrate dehydrogenase NADP-dependent, dimeric, prokaryotic GO:0004450|GO:0006099|GO:0055114 KEGG: 00020+1.1.1.42|KEGG: 00480+1.1.1.42|KEGG: 00720+1.1.1.42|MetaCyc: PWY-5913|MetaCyc: PWY-6549|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7124|MetaCyc: PWY-7254|MetaCyc: PWY-7268 AF_0647 4a215462b44fdc1e9ca0bd4ef6a4de96 412 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 297 316 - T 31-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 AF_0647 4a215462b44fdc1e9ca0bd4ef6a4de96 412 SMART SM01329 29 405 3.4E-185 T 31-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AF_0878 0adab6b11537bd6a9682f6bca7e81f2b 197 Pfam PF01973 Protein of unknown function DUF115 64 169 9.1E-14 T 31-10-2018 IPR002826 6-hydroxymethylpterin diphosphokinase MptE-like AF_0878 0adab6b11537bd6a9682f6bca7e81f2b 197 Hamap MF_02131 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase [mptE]. 1 193 32.531 T 31-10-2018 IPR027510 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, MptE GO:0003848|GO:0005524 KEGG: 00790+2.7.6.3|MetaCyc: PWY-6147|MetaCyc: PWY-6148|MetaCyc: PWY-6797|MetaCyc: PWY-7539|MetaCyc: PWY-7852|MetaCyc: PWY-7853 AF_2377 e1d354ee31665bc235351ade709f0c55 107 SUPERFAMILY SSF53146 2 107 1.83E-32 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily AF_2377 e1d354ee31665bc235351ade709f0c55 107 Gene3D G3DSA:3.30.420.130 1 100 1.9E-28 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily AF_2377 e1d354ee31665bc235351ade709f0c55 107 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 2 89 5.6E-25 T 31-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis AF_1029 d3f42f12db00d8b65a093b7da4736af4 593 ProSitePatterns PS00455 Putative AMP-binding domain signature. 199 210 - T 31-10-2018 IPR020845 AMP-binding, conserved site AF_1029 d3f42f12db00d8b65a093b7da4736af4 593 Gene3D G3DSA:2.30.38.10 403 484 1.0E-66 T 31-10-2018 AF_1029 d3f42f12db00d8b65a093b7da4736af4 593 Gene3D G3DSA:3.40.50.980 274 402 1.0E-66 T 31-10-2018 AF_1029 d3f42f12db00d8b65a093b7da4736af4 593 SUPERFAMILY SSF56801 25 587 1.83E-149 T 31-10-2018 AF_1029 d3f42f12db00d8b65a093b7da4736af4 593 Pfam PF13193 AMP-binding enzyme C-terminal domain 500 577 2.7E-21 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AF_1029 d3f42f12db00d8b65a093b7da4736af4 593 Pfam PF00501 AMP-binding enzyme 40 491 1.9E-104 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_1029 d3f42f12db00d8b65a093b7da4736af4 593 Gene3D G3DSA:3.40.50.12780 19 242 4.3E-54 T 31-10-2018 AF_1029 d3f42f12db00d8b65a093b7da4736af4 593 Gene3D G3DSA:3.30.300.310 487 592 1.8E-31 T 31-10-2018 AF_2233 3323f411f6d5a31de790c9229f970142 741 ProSitePatterns PS00435 Peroxidases proximal heme-ligand signature. 241 251 - T 31-10-2018 IPR019793 Peroxidases heam-ligand binding site Reactome: R-HSA-2408557 AF_2233 3323f411f6d5a31de790c9229f970142 741 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 16 38 2.5E-43 T 31-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AF_2233 3323f411f6d5a31de790c9229f970142 741 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 40 53 2.5E-43 T 31-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AF_2233 3323f411f6d5a31de790c9229f970142 741 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 249 272 2.5E-43 T 31-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AF_2233 3323f411f6d5a31de790c9229f970142 741 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 55 80 2.5E-43 T 31-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AF_2233 3323f411f6d5a31de790c9229f970142 741 PRINTS PR00460 Bacterial haem catalase-peroxidase signature 462 488 2.5E-43 T 31-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AF_2233 3323f411f6d5a31de790c9229f970142 741 PRINTS PR00458 Haem peroxidase superfamily signature 138 155 1.4E-15 T 31-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AF_2233 3323f411f6d5a31de790c9229f970142 741 PRINTS PR00458 Haem peroxidase superfamily signature 156 168 1.4E-15 T 31-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AF_2233 3323f411f6d5a31de790c9229f970142 741 PRINTS PR00458 Haem peroxidase superfamily signature 300 315 1.4E-15 T 31-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AF_2233 3323f411f6d5a31de790c9229f970142 741 PRINTS PR00458 Haem peroxidase superfamily signature 78 92 1.4E-15 T 31-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AF_2233 3323f411f6d5a31de790c9229f970142 741 PRINTS PR00458 Haem peroxidase superfamily signature 241 256 1.4E-15 T 31-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AF_2233 3323f411f6d5a31de790c9229f970142 741 Gene3D G3DSA:1.10.420.20 179 379 3.7E-188 T 31-10-2018 AF_2233 3323f411f6d5a31de790c9229f970142 741 Gene3D G3DSA:1.10.520.10 16 412 3.7E-188 T 31-10-2018 AF_2233 3323f411f6d5a31de790c9229f970142 741 SUPERFAMILY SSF48113 12 411 6.78E-137 T 31-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 AF_2233 3323f411f6d5a31de790c9229f970142 741 TIGRFAM TIGR00198 cat_per_HPI: catalase/peroxidase HPI 2 728 0.0 T 31-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AF_2233 3323f411f6d5a31de790c9229f970142 741 SUPERFAMILY SSF48113 412 725 5.75E-101 T 31-10-2018 IPR010255 Haem peroxidase GO:0004601|GO:0006979|GO:0020037|GO:0055114 AF_2233 3323f411f6d5a31de790c9229f970142 741 ProSitePatterns PS00436 Peroxidases active site signature. 78 89 - T 31-10-2018 IPR019794 Peroxidase, active site GO:0004601|GO:0055114 AF_2233 3323f411f6d5a31de790c9229f970142 741 Pfam PF00141 Peroxidase 72 377 7.4E-44 T 31-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AF_2233 3323f411f6d5a31de790c9229f970142 741 Pfam PF00141 Peroxidase 385 698 4.7E-32 T 31-10-2018 IPR002016 Haem peroxidase, plant/fungal/bacterial GO:0004601|GO:0006979|GO:0020037|GO:0055114 AF_2233 3323f411f6d5a31de790c9229f970142 741 Hamap MF_01961 Catalase-peroxidase [katG]. 2 726 38.871 T 31-10-2018 IPR000763 Catalase-peroxidase haem GO:0004096|GO:0004601|GO:0006979|GO:0020037|GO:0055114 KEGG: 00360+1.11.1.21|KEGG: 00380+1.11.1.21|KEGG: 00940+1.11.1.21|KEGG: 00983+1.11.1.21|MetaCyc: PWY-5506 AF_2233 3323f411f6d5a31de790c9229f970142 741 Gene3D G3DSA:1.10.420.10 571 701 9.0E-132 T 31-10-2018 AF_2233 3323f411f6d5a31de790c9229f970142 741 Gene3D G3DSA:1.10.520.10 415 725 9.0E-132 T 31-10-2018 AF_1974 394242135802dc04e57a6117dbdee279 322 SUPERFAMILY SSF51569 4 321 5.71E-135 T 31-10-2018 AF_1974 394242135802dc04e57a6117dbdee279 322 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 151 170 1.1E-60 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AF_1974 394242135802dc04e57a6117dbdee279 322 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 241 257 1.1E-60 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AF_1974 394242135802dc04e57a6117dbdee279 322 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 266 281 1.1E-60 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AF_1974 394242135802dc04e57a6117dbdee279 322 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 189 208 1.1E-60 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AF_1974 394242135802dc04e57a6117dbdee279 322 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 121 135 1.1E-60 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AF_1974 394242135802dc04e57a6117dbdee279 322 PRINTS PR00144 Delta-aminolevulinic acid dehydratase signature 295 314 1.1E-60 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AF_1974 394242135802dc04e57a6117dbdee279 322 SMART SM01004 4 321 2.0E-228 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AF_1974 394242135802dc04e57a6117dbdee279 322 Gene3D G3DSA:3.20.20.70 4 322 6.0E-145 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1974 394242135802dc04e57a6117dbdee279 322 Pfam PF00490 Delta-aminolevulinic acid dehydratase 7 319 2.2E-145 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AF_1974 394242135802dc04e57a6117dbdee279 322 PIRSF PIRSF001415 1 322 7.1E-148 T 31-10-2018 IPR001731 Delta-aminolevulinic acid dehydratase GO:0004655|GO:0033014|GO:0046872 KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AF_1974 394242135802dc04e57a6117dbdee279 322 ProSitePatterns PS00169 Delta-aminolevulinic acid dehydratase active site. 241 253 - T 31-10-2018 IPR030656 Delta-aminolevulinic acid dehydratase, active site KEGG: 00860+4.2.1.24|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451|Reactome: R-HSA-6798695 AF_2088 17e325e53727b6759273a94963238074 261 Pfam PF01798 snoRNA binding domain, fibrillarin 103 256 1.7E-38 T 31-10-2018 IPR002687 Nop domain AF_2088 17e325e53727b6759273a94963238074 261 Gene3D G3DSA:3.30.2150.10 4 74 9.6E-45 T 31-10-2018 AF_2088 17e325e53727b6759273a94963238074 261 Gene3D G3DSA:1.10.246.90 142 261 1.1E-43 T 31-10-2018 AF_2088 17e325e53727b6759273a94963238074 261 Gene3D G3DSA:1.10.287.660 75 141 1.6E-37 T 31-10-2018 IPR029012 Helix hairpin bin domain superfamily AF_2088 17e325e53727b6759273a94963238074 261 SUPERFAMILY SSF89124 5 257 6.15E-60 T 31-10-2018 IPR036070 Nop domain superfamily AF_0951 00e4f2ccb1cc1e59e125ef9cec9ea16e 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 4 26 1.2E-14 T 31-10-2018 AF_0951 00e4f2ccb1cc1e59e125ef9cec9ea16e 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 271 278 1.2E-14 T 31-10-2018 AF_0951 00e4f2ccb1cc1e59e125ef9cec9ea16e 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 1.2E-14 T 31-10-2018 AF_0951 00e4f2ccb1cc1e59e125ef9cec9ea16e 429 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 232 246 1.2E-14 T 31-10-2018 AF_0951 00e4f2ccb1cc1e59e125ef9cec9ea16e 429 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 3 299 2.1E-56 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AF_0951 00e4f2ccb1cc1e59e125ef9cec9ea16e 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 3.7E-20 T 31-10-2018 AF_0951 00e4f2ccb1cc1e59e125ef9cec9ea16e 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 256 278 3.7E-20 T 31-10-2018 AF_0951 00e4f2ccb1cc1e59e125ef9cec9ea16e 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 3.7E-20 T 31-10-2018 AF_0951 00e4f2ccb1cc1e59e125ef9cec9ea16e 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 3.7E-20 T 31-10-2018 AF_0951 00e4f2ccb1cc1e59e125ef9cec9ea16e 429 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 3.7E-20 T 31-10-2018 AF_0951 00e4f2ccb1cc1e59e125ef9cec9ea16e 429 Gene3D G3DSA:3.50.50.60 5 310 2.6E-93 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0951 00e4f2ccb1cc1e59e125ef9cec9ea16e 429 Gene3D G3DSA:3.50.50.60 36 240 2.6E-93 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0951 00e4f2ccb1cc1e59e125ef9cec9ea16e 429 SUPERFAMILY SSF51905 145 310 2.24E-33 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0951 00e4f2ccb1cc1e59e125ef9cec9ea16e 429 SUPERFAMILY SSF51905 1 190 2.16E-42 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1290 e95e4ada7f9ce3c67e2d50e0a4fe3978 162 SUPERFAMILY SSF89028 5 153 3.27E-35 T 31-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 AF_1290 e95e4ada7f9ce3c67e2d50e0a4fe3978 162 Gene3D G3DSA:1.20.1200.10 8 158 1.0E-32 T 31-10-2018 IPR036451 Cobalamin adenosyltransferase-like superfamily KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 AF_1290 e95e4ada7f9ce3c67e2d50e0a4fe3978 162 Pfam PF01923 Cobalamin adenosyltransferase 5 151 2.0E-31 T 31-10-2018 IPR016030 Cobalamin adenosyltransferase-like KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 AF_1290 e95e4ada7f9ce3c67e2d50e0a4fe3978 162 ProDom PD007457 TRANSFERASE ADENOSYLTRANSFERASE COBALAMIN ATP:COBIALAMIN ADENOSYLTRANSFERASE PDUO TYPE RELATED ACIDURIA YVQK 14 110 1.0E-50 T 31-10-2018 IPR029499 ATP:cob(I)alamin adenosyltransferase, PduO-type KEGG: 00860+2.5.1.17|Reactome: R-HSA-196741|Reactome: R-HSA-3359471 AF_1425 c797d5322ff32ddbcda2e39f81a52c3c 380 TIGRFAM TIGR02535 hyp_Hser_kinase: proposed homoserine kinase 1 379 3.9E-167 T 31-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AF_1425 c797d5322ff32ddbcda2e39f81a52c3c 380 PIRSF PIRSF006392 1 380 8.3E-127 T 31-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AF_1425 c797d5322ff32ddbcda2e39f81a52c3c 380 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 1 380 39.757 T 31-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AF_1425 c797d5322ff32ddbcda2e39f81a52c3c 380 SUPERFAMILY SSF53649 1 349 5.45E-33 T 31-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AF_1425 c797d5322ff32ddbcda2e39f81a52c3c 380 Gene3D G3DSA:3.30.70.2130 78 210 2.0E-115 T 31-10-2018 AF_1425 c797d5322ff32ddbcda2e39f81a52c3c 380 Gene3D G3DSA:3.40.720.10 4 375 2.0E-115 T 31-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AF_1425 c797d5322ff32ddbcda2e39f81a52c3c 380 Pfam PF01676 Metalloenzyme superfamily 1 379 8.4E-50 T 31-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 AF_1425 c797d5322ff32ddbcda2e39f81a52c3c 380 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 37 193 1.1E-48 T 31-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AF_1425 c797d5322ff32ddbcda2e39f81a52c3c 380 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 4 379 2.6E-157 T 31-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AF_0886 f62ce06ea1dda6503bb839486aa3a4de 326 SUPERFAMILY SSF52283 16 317 5.27E-9 T 31-10-2018 AF_0886 f62ce06ea1dda6503bb839486aa3a4de 326 Gene3D G3DSA:3.40.50.720 133 279 2.2E-48 T 31-10-2018 AF_0886 f62ce06ea1dda6503bb839486aa3a4de 326 ProSitePatterns PS00739 S-adenosyl-L-homocysteine hydrolase signature 2. 152 168 - T 31-10-2018 IPR020082 S-adenosyl-L-homocysteine hydrolase, conserved site GO:0004013 KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AF_0886 f62ce06ea1dda6503bb839486aa3a4de 326 Gene3D G3DSA:3.40.50.1480 10 320 2.2E-48 T 31-10-2018 AF_0886 f62ce06ea1dda6503bb839486aa3a4de 326 Pfam PF00670 S-adenosyl-L-homocysteine hydrolase, NAD binding domain 133 241 1.7E-18 T 31-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AF_0886 f62ce06ea1dda6503bb839486aa3a4de 326 SMART SM00996 1 326 5.5E-4 T 31-10-2018 IPR000043 Adenosylhomocysteinase-like KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AF_0886 f62ce06ea1dda6503bb839486aa3a4de 326 SMART SM00997 131 279 4.3E-38 T 31-10-2018 IPR015878 S-adenosyl-L-homocysteine hydrolase, NAD binding domain KEGG: 00270+3.3.1.1|MetaCyc: PWY-5041 AF_0886 f62ce06ea1dda6503bb839486aa3a4de 326 SUPERFAMILY SSF51735 131 279 2.16E-23 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0525 febd9aff9a024317a341fbd47cca79fb 259 SUPERFAMILY SSF159659 11 248 1.83E-51 T 31-10-2018 AF_0525 febd9aff9a024317a341fbd47cca79fb 259 Pfam PF09754 PAC2 family 23 237 2.1E-53 T 31-10-2018 IPR019151 Proteasome assembly chaperone 2 AF_0525 febd9aff9a024317a341fbd47cca79fb 259 TIGRFAM TIGR00162 TIGR00162: TIGR00162 family protein 1 259 1.0E-142 T 31-10-2018 IPR004426 Conserved hypothetical protein CHP00062 AF_0525 febd9aff9a024317a341fbd47cca79fb 259 Gene3D G3DSA:3.40.50.10900 7 257 2.1E-69 T 31-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily AF_1014 8f47f99016d5f67b64f047f6e13c50ed 547 Gene3D G3DSA:3.50.30.80 369 519 6.4E-58 T 31-10-2018 AF_1014 8f47f99016d5f67b64f047f6e13c50ed 547 ProSitePatterns PS00887 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 2. 456 467 - T 31-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AF_1014 8f47f99016d5f67b64f047f6e13c50ed 547 Hamap MF_00012 Dihydroxy-acid dehydratase [ilvD]. 1 547 44.654 T 31-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AF_1014 8f47f99016d5f67b64f047f6e13c50ed 547 ProSitePatterns PS00886 Dihydroxy-acid and 6-phosphogluconate dehydratases signature 1. 119 129 - T 31-10-2018 IPR020558 Dihydroxy-acid/6-phosphogluconate dehydratase, conserved site GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AF_1014 8f47f99016d5f67b64f047f6e13c50ed 547 TIGRFAM TIGR00110 ilvD: dihydroxy-acid dehydratase 14 546 7.4E-261 T 31-10-2018 IPR004404 Dihydroxy-acid dehydratase GO:0004160|GO:0009082 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AF_1014 8f47f99016d5f67b64f047f6e13c50ed 547 Pfam PF00920 Dehydratase family 31 544 9.0E-209 T 31-10-2018 IPR000581 Dihydroxy-acid/6-phosphogluconate dehydratase GO:0003824 KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AF_1014 8f47f99016d5f67b64f047f6e13c50ed 547 SUPERFAMILY SSF143975 1 368 6.41E-124 T 31-10-2018 IPR037237 IlvD/EDD, N-terminal domain KEGG: 00290+4.2.1.9|KEGG: 00770+4.2.1.9|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-7111 AF_1014 8f47f99016d5f67b64f047f6e13c50ed 547 SUPERFAMILY SSF52016 369 546 1.33E-61 T 31-10-2018 AF_0157 abfda00907d05aef5be3bb683a2d0d95 180 SUPERFAMILY SSF54862 1 174 9.21E-56 T 31-10-2018 AF_0157 abfda00907d05aef5be3bb683a2d0d95 180 Pfam PF13247 4Fe-4S dicluster domain 50 143 1.2E-24 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0157 abfda00907d05aef5be3bb683a2d0d95 180 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 89 100 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0157 abfda00907d05aef5be3bb683a2d0d95 180 Gene3D G3DSA:3.30.70.20 7 174 6.5E-54 T 31-10-2018 AF_0157 abfda00907d05aef5be3bb683a2d0d95 180 Gene3D G3DSA:3.30.70.20 63 115 6.5E-54 T 31-10-2018 AF_0245 83ae5b87930973a64aea23398ef6725e 192 SUPERFAMILY SSF50037 123 188 4.81E-9 T 31-10-2018 IPR008988 Transcriptional repressor, C-terminal AF_0245 83ae5b87930973a64aea23398ef6725e 192 SMART SM00899 121 190 7.8E-12 T 31-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 AF_0245 83ae5b87930973a64aea23398ef6725e 192 Gene3D G3DSA:2.30.30.90 121 191 2.0E-10 T 31-10-2018 IPR038157 Ferrous iron transporter, core domain AF_0245 83ae5b87930973a64aea23398ef6725e 192 Gene3D G3DSA:1.10.10.10 3 107 3.6E-31 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0245 83ae5b87930973a64aea23398ef6725e 192 SMART SM00529 1 96 1.1E-34 T 31-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 AF_0245 83ae5b87930973a64aea23398ef6725e 192 Pfam PF04023 FeoA domain 122 188 3.6E-9 T 31-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 AF_0245 83ae5b87930973a64aea23398ef6725e 192 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 38 104 7.9E-26 T 31-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 AF_0245 83ae5b87930973a64aea23398ef6725e 192 SUPERFAMILY SSF47979 38 112 1.7E-23 T 31-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 AF_0590 6364ef3aca1aad8d5301a71795373fdb 281 Pfam PF01634 ATP phosphoribosyltransferase 2 174 1.8E-31 T 31-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 AF_0590 6364ef3aca1aad8d5301a71795373fdb 281 TIGRFAM TIGR00070 hisG: ATP phosphoribosyltransferase 1 144 3.3E-23 T 31-10-2018 IPR013820 ATP phosphoribosyltransferase, catalytic domain GO:0000105|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 AF_0590 6364ef3aca1aad8d5301a71795373fdb 281 SUPERFAMILY SSF53850 1 179 4.34E-25 T 31-10-2018 AF_0590 6364ef3aca1aad8d5301a71795373fdb 281 TIGRFAM TIGR03455 HisG_C-term: ATP phosphoribosyltransferase, C-terminal domain 153 252 2.0E-23 T 31-10-2018 IPR013115 Histidine biosynthesis HisG, C-terminal GO:0000105|GO:0000287|GO:0003879|GO:0005737 KEGG: 00340+2.4.2.17 AF_0590 6364ef3aca1aad8d5301a71795373fdb 281 Gene3D G3DSA:3.40.190.10 48 145 2.7E-17 T 31-10-2018 AF_0531 1836d0a4f5e7f5fdcfe49c251daf720a 243 Pfam PF00899 ThiF family 2 218 2.0E-57 T 31-10-2018 IPR000594 THIF-type NAD/FAD binding fold GO:0008641 AF_0531 1836d0a4f5e7f5fdcfe49c251daf720a 243 Gene3D G3DSA:3.40.50.720 1 226 2.4E-73 T 31-10-2018 AF_0531 1836d0a4f5e7f5fdcfe49c251daf720a 243 SUPERFAMILY SSF69572 2 224 3.27E-78 T 31-10-2018 IPR035985 Ubiquitin-activating enzyme GO:0008641 AF_0887 0d759d27f9db592fb1aa32966a136bb8 495 Gene3D G3DSA:3.40.50.300 1 232 5.1E-56 T 31-10-2018 AF_0887 0d759d27f9db592fb1aa32966a136bb8 495 Pfam PF00005 ABC transporter 15 163 9.3E-33 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0887 0d759d27f9db592fb1aa32966a136bb8 495 SUPERFAMILY SSF52540 2 215 5.21E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0887 0d759d27f9db592fb1aa32966a136bb8 495 SUPERFAMILY SSF52540 250 474 1.88E-44 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0887 0d759d27f9db592fb1aa32966a136bb8 495 Gene3D G3DSA:3.40.50.300 248 482 7.2E-44 T 31-10-2018 AF_0887 0d759d27f9db592fb1aa32966a136bb8 495 SMART SM00382 23 211 1.8E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0887 0d759d27f9db592fb1aa32966a136bb8 495 Pfam PF00005 ABC transporter 268 419 6.0E-18 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0887 0d759d27f9db592fb1aa32966a136bb8 495 ProSitePatterns PS00211 ABC transporters family signature. 392 406 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_1540 3777164513514a30d3e859b8b228d879 383 ProSitePatterns PS01217 ATP-citrate lyase / succinyl-CoA ligases family signature 3. 249 274 - T 31-10-2018 IPR017866 Succinyl-CoA synthetase, beta subunit, conserved site KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1540 3777164513514a30d3e859b8b228d879 383 Gene3D G3DSA:3.30.1490.20 22 97 6.2E-85 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AF_1540 3777164513514a30d3e859b8b228d879 383 Hamap MF_00558 Succinate--CoA ligase [ADP-forming] subunit beta [sucC]. 2 383 39.468 T 31-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AF_1540 3777164513514a30d3e859b8b228d879 383 Gene3D G3DSA:3.40.50.261 232 383 4.6E-46 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1540 3777164513514a30d3e859b8b228d879 383 TIGRFAM TIGR01016 sucCoAbeta: succinate-CoA ligase, beta subunit 2 382 2.5E-143 T 31-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AF_1540 3777164513514a30d3e859b8b228d879 383 Pfam PF00549 CoA-ligase 255 357 3.1E-16 T 31-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1540 3777164513514a30d3e859b8b228d879 383 PIRSF PIRSF001554 2 383 4.5E-142 T 31-10-2018 IPR005809 Succinate--CoA synthetase, beta subunit GO:0006099 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AF_1540 3777164513514a30d3e859b8b228d879 383 SUPERFAMILY SSF56059 2 230 1.29E-73 T 31-10-2018 AF_1540 3777164513514a30d3e859b8b228d879 383 SUPERFAMILY SSF52210 231 381 1.96E-42 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1540 3777164513514a30d3e859b8b228d879 383 Gene3D G3DSA:3.30.470.20 2 226 6.2E-85 T 31-10-2018 AF_1540 3777164513514a30d3e859b8b228d879 383 Pfam PF08442 ATP-grasp domain 3 195 1.1E-75 T 31-10-2018 IPR013650 ATP-grasp fold, succinyl-CoA synthetase-type KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AF_0683 3e08b3d4a952b355304cc6387d37fe37 124 Gene3D G3DSA:1.20.1300.10 11 121 1.0E-14 T 31-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_0683 3e08b3d4a952b355304cc6387d37fe37 124 SUPERFAMILY SSF81343 16 119 9.16E-18 T 31-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_0683 3e08b3d4a952b355304cc6387d37fe37 124 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 14 112 9.2E-12 T 31-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_1630 03cb7125e8c0f45cbdd8dc635139ba73 82 TIGRFAM TIGR00286 TIGR00286: arginine decarboxylase, pyruvoyl-dependent 3 82 2.7E-34 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AF_1630 03cb7125e8c0f45cbdd8dc635139ba73 82 Hamap MF_01404 Pyruvoyl-dependent arginine decarboxylase [pdaD]. 1 82 42.27 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AF_1630 03cb7125e8c0f45cbdd8dc635139ba73 82 Pfam PF01862 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) 4 81 8.6E-33 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AF_1630 03cb7125e8c0f45cbdd8dc635139ba73 82 SUPERFAMILY SSF56271 3 81 9.94E-29 T 31-10-2018 IPR016104 Pyruvoyl-dependent histidine/arginine decarboxylase GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AF_1630 03cb7125e8c0f45cbdd8dc635139ba73 82 Gene3D G3DSA:3.50.20.10 1 82 7.6E-27 T 31-10-2018 IPR016105 Pyruvoyl-dependent histidine/arginine decarboxylase, 3-layer sandwich domain GO:0006520|GO:0016831 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AF_1630 03cb7125e8c0f45cbdd8dc635139ba73 82 ProDom PD010449 DECARBOXYLASE PYRUVOYL-DEPENDENT ARGININE SUBUNIT ALPHA CONTAINS: BETA PVLARGDC LYA DECARBOX 5 82 6.0E-32 T 31-10-2018 IPR002724 Pyruvoyl-dependent arginine decarboxylase GO:0006527|GO:0008792 KEGG: 00330+4.1.1.19|MetaCyc: PWY-40|MetaCyc: PWY-43|MetaCyc: PWY-6305|MetaCyc: PWY-6834 AF_1312 cab4cd2f4ff0929788930fd38589c889 338 Pfam PF17131 Outer membrane lipoprotein-sorting protein 92 181 6.6E-9 T 31-10-2018 IPR033399 Putative outer membrane lipoprotein-sorting protein AF_1312 cab4cd2f4ff0929788930fd38589c889 338 Gene3D G3DSA:2.50.20.10 31 223 6.7E-38 T 31-10-2018 AF_1312 cab4cd2f4ff0929788930fd38589c889 338 SUPERFAMILY SSF89392 37 220 6.28E-31 T 31-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX AF_1312 cab4cd2f4ff0929788930fd38589c889 338 Pfam PF14285 Domain of unknown function (DUF4367) 252 337 2.7E-12 T 31-10-2018 IPR025377 Domain of unknown function DUF4367 AF_0975 b0f2fd7c961240d141cdb05f17da2dbd 642 SUPERFAMILY SSF56801 26 637 2.88E-167 T 31-10-2018 AF_0975 b0f2fd7c961240d141cdb05f17da2dbd 642 Pfam PF16177 Acetyl-coenzyme A synthetase N-terminus 32 89 2.4E-12 T 31-10-2018 IPR032387 Acetyl-coenzyme A synthetase, N-terminal domain KEGG: 00010+6.2.1.1|KEGG: 00620+6.2.1.1|KEGG: 00630+6.2.1.1|KEGG: 00640+6.2.1.1|KEGG: 00680+6.2.1.1|KEGG: 00720+6.2.1.1|MetaCyc: PWY-5108|MetaCyc: PWY-5132|MetaCyc: PWY-5133|MetaCyc: PWY-6672|MetaCyc: PWY-7118|MetaCyc: PWY-7857 AF_0975 b0f2fd7c961240d141cdb05f17da2dbd 642 Gene3D G3DSA:3.40.50.12780 73 516 1.0E-96 T 31-10-2018 AF_0975 b0f2fd7c961240d141cdb05f17da2dbd 642 Gene3D G3DSA:3.30.300.30 517 641 1.2E-26 T 31-10-2018 AF_0975 b0f2fd7c961240d141cdb05f17da2dbd 642 ProSitePatterns PS00455 Putative AMP-binding domain signature. 262 273 - T 31-10-2018 IPR020845 AMP-binding, conserved site AF_0975 b0f2fd7c961240d141cdb05f17da2dbd 642 Pfam PF13193 AMP-binding enzyme C-terminal domain 529 607 9.2E-23 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AF_0975 b0f2fd7c961240d141cdb05f17da2dbd 642 Pfam PF00501 AMP-binding enzyme 93 520 3.2E-85 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_1622 36f050e3ed64e0d176199334a5028599 163 SUPERFAMILY SSF54909 66 147 4.29E-17 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel AF_1622 36f050e3ed64e0d176199334a5028599 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 1.2E-5 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_1622 36f050e3ed64e0d176199334a5028599 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 1.2E-5 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_1622 36f050e3ed64e0d176199334a5028599 163 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 1.2E-5 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_1622 36f050e3ed64e0d176199334a5028599 163 Gene3D G3DSA:3.30.70.920 53 150 6.9E-21 T 31-10-2018 AF_1622 36f050e3ed64e0d176199334a5028599 163 Pfam PF01037 Lrp/AsnC ligand binding domain 70 142 7.8E-16 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AF_1622 36f050e3ed64e0d176199334a5028599 163 Pfam PF13412 Winged helix-turn-helix DNA-binding 5 47 6.0E-9 T 31-10-2018 AF_1622 36f050e3ed64e0d176199334a5028599 163 SMART SM00344 3 111 2.1E-11 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AF_1622 36f050e3ed64e0d176199334a5028599 163 Gene3D G3DSA:1.10.10.10 2 52 2.6E-10 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1622 36f050e3ed64e0d176199334a5028599 163 SUPERFAMILY SSF46785 3 59 7.23E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1798 ef92333c6640e39f42caa30781cda1d9 333 Pfam PF01384 Phosphate transporter family 19 321 4.1E-104 T 31-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 AF_0367 9b921021c14ede02c6bbe31bc6d6a43a 397 SUPERFAMILY SSF103473 4 396 4.45E-67 T 31-10-2018 IPR036259 MFS transporter superfamily AF_0367 9b921021c14ede02c6bbe31bc6d6a43a 397 Gene3D G3DSA:1.20.1250.20 1 397 3.8E-68 T 31-10-2018 AF_0367 9b921021c14ede02c6bbe31bc6d6a43a 397 Pfam PF07690 Major Facilitator Superfamily 11 349 6.7E-44 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AF_0929 4d5f30888ffc3c95e44c875ec64791b1 241 Gene3D G3DSA:3.20.20.70 31 241 1.0E-64 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0929 4d5f30888ffc3c95e44c875ec64791b1 241 SUPERFAMILY SSF51366 29 237 1.07E-52 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AF_0929 4d5f30888ffc3c95e44c875ec64791b1 241 Hamap MF_01200_A Orotidine 5'-phosphate decarboxylase [pyrF]. 36 241 37.074 T 31-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AF_0929 4d5f30888ffc3c95e44c875ec64791b1 241 SMART SM00934 35 235 1.3E-51 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AF_0929 4d5f30888ffc3c95e44c875ec64791b1 241 Pfam PF00215 Orotidine 5'-phosphate decarboxylase / HUMPS family 35 234 1.4E-37 T 31-10-2018 IPR001754 Orotidine 5'-phosphate decarboxylase domain GO:0004590|GO:0006207 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AF_0929 4d5f30888ffc3c95e44c875ec64791b1 241 TIGRFAM TIGR01740 pyrF: orotidine 5'-phosphate decarboxylase 36 236 7.8E-59 T 31-10-2018 IPR014732 Orotidine 5'-phosphate decarboxylase GO:0004590|GO:0044205 KEGG: 00240+4.1.1.23|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AF_0430 1f2c9fbb94f35bdb3cefc1cb9e8dab99 248 Pfam PF00005 ABC transporter 18 162 2.7E-30 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0430 1f2c9fbb94f35bdb3cefc1cb9e8dab99 248 SUPERFAMILY SSF52540 2 222 4.62E-60 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0430 1f2c9fbb94f35bdb3cefc1cb9e8dab99 248 SMART SM00382 26 211 9.0E-19 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0430 1f2c9fbb94f35bdb3cefc1cb9e8dab99 248 ProSitePatterns PS00211 ABC transporters family signature. 134 148 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_0430 1f2c9fbb94f35bdb3cefc1cb9e8dab99 248 Gene3D G3DSA:3.40.50.300 1 245 2.9E-68 T 31-10-2018 AF_2395 c569953204a6e068c1f20810ebe9018c 148 Gene3D G3DSA:1.10.10.10 3 67 1.7E-24 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_2395 c569953204a6e068c1f20810ebe9018c 148 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 1 60 9.8E-27 T 31-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 AF_2395 c569953204a6e068c1f20810ebe9018c 148 SMART SM00529 24 122 1.2E-43 T 31-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 AF_2395 c569953204a6e068c1f20810ebe9018c 148 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 63 130 1.4E-15 T 31-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 AF_2395 c569953204a6e068c1f20810ebe9018c 148 SUPERFAMILY SSF46785 4 62 2.41E-15 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_2395 c569953204a6e068c1f20810ebe9018c 148 SUPERFAMILY SSF47979 63 140 1.44E-17 T 31-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 AF_2395 c569953204a6e068c1f20810ebe9018c 148 Gene3D G3DSA:1.10.60.10 68 121 2.3E-18 T 31-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 AF_2064 f9b3f32266169ba6ea14a0f161e4eca4 57 Pfam PF01775 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A 9 55 9.8E-12 T 31-10-2018 IPR023573 Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2064 f9b3f32266169ba6ea14a0f161e4eca4 57 SUPERFAMILY SSF160374 3 56 1.83E-18 T 31-10-2018 AF_2064 f9b3f32266169ba6ea14a0f161e4eca4 57 Hamap MF_00273 50S ribosomal protein L18Ae [rpl18a]. 1 55 18.947 T 31-10-2018 IPR028877 50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2064 f9b3f32266169ba6ea14a0f161e4eca4 57 Gene3D G3DSA:3.10.20.10 1 55 5.2E-25 T 31-10-2018 AF_2064 f9b3f32266169ba6ea14a0f161e4eca4 57 ProDom PD010302 RIBOSOMAL LX 50S RIBONUCLEOPROTEIN HL32 DIRECT SEQUENCING LXA LSU 3 54 3.0E-23 T 31-10-2018 IPR002768 50S ribosomal protein L18Ae, archaea GO:0003735|GO:0005840|GO:0006412 AF_2373 2c4faa0bbe8e26ea1e8f9605845785f2 249 Pfam PF01513 ATP-NAD kinase 38 231 6.3E-41 T 31-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AF_2373 2c4faa0bbe8e26ea1e8f9605845785f2 249 SUPERFAMILY SSF111331 5 232 8.37E-58 T 31-10-2018 IPR016064 NAD kinase/diacylglycerol kinase-like domain superfamily AF_2373 2c4faa0bbe8e26ea1e8f9605845785f2 249 Gene3D G3DSA:2.60.200.30 102 226 1.7E-88 T 31-10-2018 IPR017437 ATP-NAD kinase, PpnK-type, C-terminal GO:0003951|GO:0019674 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AF_2373 2c4faa0bbe8e26ea1e8f9605845785f2 249 Hamap MF_00361 NAD kinase [nadK]. 1 247 23.387 T 31-10-2018 IPR002504 NAD kinase GO:0003951|GO:0006741 KEGG: 00760+2.7.1.23|MetaCyc: PWY-5083|MetaCyc: PWY-7268|MetaCyc: PWY-7269|Reactome: R-HSA-196807 AF_2373 2c4faa0bbe8e26ea1e8f9605845785f2 249 Gene3D G3DSA:3.40.50.10330 15 238 1.7E-88 T 31-10-2018 IPR017438 Inorganic polyphosphate/ATP-NAD kinase, N-terminal GO:0003951 AF_2009 eccf42dd586fea1267ad74db5dfec01f 468 TIGRFAM TIGR04085 rSAM_more_4Fe4S: radical SAM additional 4Fe4S-binding SPASM domain 366 451 7.3E-15 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain AF_2009 eccf42dd586fea1267ad74db5dfec01f 468 SMART SM00729 114 312 2.3E-10 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AF_2009 eccf42dd586fea1267ad74db5dfec01f 468 Pfam PF04055 Radical SAM superfamily 121 272 6.1E-25 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_2009 eccf42dd586fea1267ad74db5dfec01f 468 SUPERFAMILY SSF102114 113 432 6.93E-76 T 31-10-2018 AF_2009 eccf42dd586fea1267ad74db5dfec01f 468 Pfam PF13186 Iron-sulfur cluster-binding domain 366 424 1.1E-8 T 31-10-2018 IPR023885 4Fe4S-binding SPASM domain AF_2009 eccf42dd586fea1267ad74db5dfec01f 468 Gene3D G3DSA:3.20.20.70 113 414 2.2E-65 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_2009 eccf42dd586fea1267ad74db5dfec01f 468 Pfam PF13353 4Fe-4S single cluster domain 118 226 3.7E-10 T 31-10-2018 AF_1627 6e91565c4ee4e3714b91ab3f9a303f9a 71 SUPERFAMILY SSF47413 3 64 1.61E-19 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AF_1627 6e91565c4ee4e3714b91ab3f9a303f9a 71 SMART SM00530 4 59 3.4E-17 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AF_1627 6e91565c4ee4e3714b91ab3f9a303f9a 71 Gene3D G3DSA:1.10.260.40 1 65 6.7E-28 T 31-10-2018 AF_1627 6e91565c4ee4e3714b91ab3f9a303f9a 71 Pfam PF01381 Helix-turn-helix 5 58 8.2E-17 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AF_0665 b4824608a965290947ac654f05710111 195 Pfam PF01163 RIO1 family 10 126 1.5E-10 T 31-10-2018 AF_0665 b4824608a965290947ac654f05710111 195 Gene3D G3DSA:1.10.510.10 76 190 2.5E-23 T 31-10-2018 AF_0665 b4824608a965290947ac654f05710111 195 SUPERFAMILY SSF56112 15 176 5.26E-23 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily AF_0665 b4824608a965290947ac654f05710111 195 Gene3D G3DSA:3.30.200.20 9 74 6.8E-19 T 31-10-2018 AF_0665 b4824608a965290947ac654f05710111 195 ProSitePatterns PS00109 Tyrosine protein kinases specific active-site signature. 103 115 - T 31-10-2018 IPR008266 Tyrosine-protein kinase, active site GO:0004672|GO:0006468 AF_0665 b4824608a965290947ac654f05710111 195 TIGRFAM TIGR03724 arch_bud32: Kae1-associated kinase Bud32 5 189 2.8E-66 T 31-10-2018 IPR022495 Serine/threonine-protein kinase Bud32 GO:0004674 KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1|Reactome: R-HSA-6782315|Reactome: R-HSA-6804756 AF_1370 40a8fec16ada20692a4ea38254ef4901 371 PIRSF PIRSF005622 9 371 9.0E-145 T 31-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 AF_1370 40a8fec16ada20692a4ea38254ef4901 371 Gene3D G3DSA:3.40.50.11750 24 258 2.5E-103 T 31-10-2018 AF_1370 40a8fec16ada20692a4ea38254ef4901 371 Gene3D G3DSA:1.10.10.2140 317 367 4.3E-23 T 31-10-2018 AF_1370 40a8fec16ada20692a4ea38254ef4901 371 Gene3D G3DSA:3.40.50.11740 68 298 2.5E-103 T 31-10-2018 AF_1370 40a8fec16ada20692a4ea38254ef4901 371 Pfam PF01924 Hydrogenase formation hypA family 22 364 8.8E-135 T 31-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 AF_1370 40a8fec16ada20692a4ea38254ef4901 371 TIGRFAM TIGR00075 hypD: hydrogenase expression/formation protein HypD 1 370 1.4E-170 T 31-10-2018 IPR002780 Hydrogenase formation HypD protein GO:0046872 AF_1256 5f9ed19bfe31b9aae4a0b15948dd6c2a 128 SUPERFAMILY SSF52172 9 125 6.83E-33 T 31-10-2018 IPR011006 CheY-like superfamily AF_1256 5f9ed19bfe31b9aae4a0b15948dd6c2a 128 Gene3D G3DSA:3.40.50.2300 4 128 9.9E-34 T 31-10-2018 AF_1256 5f9ed19bfe31b9aae4a0b15948dd6c2a 128 Pfam PF00072 Response regulator receiver domain 12 119 1.8E-24 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_1256 5f9ed19bfe31b9aae4a0b15948dd6c2a 128 SMART SM00448 10 119 1.8E-27 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_0349 2777f5651b9e8abde7f029cc76179aad 84 Pfam PF00582 Universal stress protein family 21 84 1.5E-12 T 31-10-2018 IPR006016 UspA AF_0349 2777f5651b9e8abde7f029cc76179aad 84 Gene3D G3DSA:3.40.50.620 17 84 1.7E-17 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_0349 2777f5651b9e8abde7f029cc76179aad 84 SUPERFAMILY SSF52402 2 84 7.12E-15 T 31-10-2018 AF_2144 a04e2f5f49d1662a49ee0d660e538872 105 Gene3D G3DSA:3.40.30.10 1 104 1.2E-34 T 31-10-2018 AF_2144 a04e2f5f49d1662a49ee0d660e538872 105 PRINTS PR00421 Thioredoxin family signature 19 27 1.0E-7 T 31-10-2018 AF_2144 a04e2f5f49d1662a49ee0d660e538872 105 PRINTS PR00421 Thioredoxin family signature 67 78 1.0E-7 T 31-10-2018 AF_2144 a04e2f5f49d1662a49ee0d660e538872 105 PRINTS PR00421 Thioredoxin family signature 27 36 1.0E-7 T 31-10-2018 AF_2144 a04e2f5f49d1662a49ee0d660e538872 105 SUPERFAMILY SSF52833 4 103 2.5E-37 T 31-10-2018 IPR036249 Thioredoxin-like superfamily AF_2144 a04e2f5f49d1662a49ee0d660e538872 105 PIRSF PIRSF000077 1 103 4.0E-35 T 31-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AF_2144 a04e2f5f49d1662a49ee0d660e538872 105 TIGRFAM TIGR01068 thioredoxin: thioredoxin 5 102 2.4E-39 T 31-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AF_2144 a04e2f5f49d1662a49ee0d660e538872 105 Pfam PF00085 Thioredoxin 3 101 2.7E-29 T 31-10-2018 IPR013766 Thioredoxin domain GO:0045454 AF_0654 7aee18d6f45159874008f1569d3694d6 466 SUPERFAMILY SSF51905 1 461 2.25E-29 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0654 7aee18d6f45159874008f1569d3694d6 466 Gene3D G3DSA:3.50.50.60 1 84 2.0E-18 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0654 7aee18d6f45159874008f1569d3694d6 466 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 155 231 1.5E-7 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AF_0654 7aee18d6f45159874008f1569d3694d6 466 PIRSF PIRSF038984 123 465 3.9E-27 T 31-10-2018 IPR028348 FAD dependent protein AF_0654 7aee18d6f45159874008f1569d3694d6 466 PIRSF PIRSF038984 1 79 1.7E-11 T 31-10-2018 IPR028348 FAD dependent protein AF_0654 7aee18d6f45159874008f1569d3694d6 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 417 439 3.1E-10 T 31-10-2018 AF_0654 7aee18d6f45159874008f1569d3694d6 466 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 3.1E-10 T 31-10-2018 AF_0654 7aee18d6f45159874008f1569d3694d6 466 Gene3D G3DSA:3.50.50.100 140 237 1.1E-10 T 31-10-2018 AF_0654 7aee18d6f45159874008f1569d3694d6 466 Gene3D G3DSA:3.50.50.60 404 461 5.0E-6 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1749 03b7f015b725aa25192d95270c7707ed 388 Gene3D G3DSA:1.10.3430.10 1 388 1.1E-150 T 31-10-2018 IPR029020 Ammonium/urea transporter AF_1749 03b7f015b725aa25192d95270c7707ed 388 TIGRFAM TIGR00836 amt: ammonium transporter 5 387 7.0E-142 T 31-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 AF_1749 03b7f015b725aa25192d95270c7707ed 388 Pfam PF00909 Ammonium Transporter Family 8 387 2.5E-135 T 31-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 AF_1749 03b7f015b725aa25192d95270c7707ed 388 ProSitePatterns PS01219 Ammonium transporters signature. 149 174 - T 31-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 AF_1749 03b7f015b725aa25192d95270c7707ed 388 SUPERFAMILY SSF111352 2 368 7.98E-119 T 31-10-2018 AF_1400 44c03ddd4bec13896e751538816ddbe3 188 Pfam PF01955 Adenosylcobinamide amidohydrolase 23 181 4.7E-40 T 31-10-2018 IPR002808 Adenosylcobinamide amidohydrolase, CbiZ AF_1763 343687f7617b978de678aa61165d7050 474 Gene3D G3DSA:3.40.50.1820 21 237 3.2E-73 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_1763 343687f7617b978de678aa61165d7050 474 Pfam PF00561 alpha/beta hydrolase fold 24 157 3.9E-6 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_1763 343687f7617b978de678aa61165d7050 474 SUPERFAMILY SSF53474 23 172 6.61E-19 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_1763 343687f7617b978de678aa61165d7050 474 Gene3D G3DSA:2.60.40.2200 332 474 1.5E-69 T 31-10-2018 AF_1763 343687f7617b978de678aa61165d7050 474 Gene3D G3DSA:2.60.40.2190 238 331 1.1E-63 T 31-10-2018 AF_0394 ef92a0fb320b8640f71ed600c4919117 443 Gene3D G3DSA:3.30.70.2740 324 400 1.2E-9 T 31-10-2018 AF_0394 ef92a0fb320b8640f71ed600c4919117 443 Pfam PF01565 FAD binding domain 38 172 4.9E-40 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AF_0394 ef92a0fb320b8640f71ed600c4919117 443 SUPERFAMILY SSF56176 37 208 7.36E-63 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AF_0394 ef92a0fb320b8640f71ed600c4919117 443 Gene3D G3DSA:1.10.45.10 401 440 2.0E-11 T 31-10-2018 IPR016171 Vanillyl-alcohol oxidase, C-terminal subdomain 2 AF_0394 ef92a0fb320b8640f71ed600c4919117 443 Gene3D G3DSA:3.30.465.40 5 227 5.9E-67 T 31-10-2018 AF_0394 ef92a0fb320b8640f71ed600c4919117 443 SUPERFAMILY SSF55103 183 439 7.85E-47 T 31-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AF_0394 ef92a0fb320b8640f71ed600c4919117 443 Pfam PF02913 FAD linked oxidases, C-terminal domain 212 439 5.9E-58 T 31-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AF_2118 fec3007163cc83c82443f5c69378c9bf 183 Pfam PF00571 CBS domain 130 181 6.6E-9 T 31-10-2018 IPR000644 CBS domain AF_2118 fec3007163cc83c82443f5c69378c9bf 183 Pfam PF00571 CBS domain 68 119 9.5E-13 T 31-10-2018 IPR000644 CBS domain AF_2118 fec3007163cc83c82443f5c69378c9bf 183 SUPERFAMILY SSF54631 65 182 4.42E-26 T 31-10-2018 AF_2118 fec3007163cc83c82443f5c69378c9bf 183 Gene3D G3DSA:1.10.260.40 4 64 8.7E-14 T 31-10-2018 AF_2118 fec3007163cc83c82443f5c69378c9bf 183 SMART SM00116 72 119 8.6E-10 T 31-10-2018 IPR000644 CBS domain AF_2118 fec3007163cc83c82443f5c69378c9bf 183 SMART SM00116 137 182 1.0E-5 T 31-10-2018 IPR000644 CBS domain AF_2118 fec3007163cc83c82443f5c69378c9bf 183 PIRSF PIRSF037253 1 183 1.8E-81 T 31-10-2018 IPR017158 Transcription regulator, CBS domain-containing, predicted AF_2118 fec3007163cc83c82443f5c69378c9bf 183 SMART SM00530 7 58 1.4E-12 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AF_2118 fec3007163cc83c82443f5c69378c9bf 183 SUPERFAMILY SSF47413 6 56 1.07E-12 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AF_2118 fec3007163cc83c82443f5c69378c9bf 183 Gene3D G3DSA:3.10.580.10 65 183 1.5E-29 T 31-10-2018 AF_2118 fec3007163cc83c82443f5c69378c9bf 183 Pfam PF01381 Helix-turn-helix 8 55 4.0E-14 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AF_0840 291322968259fa6fd6dc95844c991ff3 577 ProSitePatterns PS00455 Putative AMP-binding domain signature. 227 238 - T 31-10-2018 IPR020845 AMP-binding, conserved site AF_0840 291322968259fa6fd6dc95844c991ff3 577 Pfam PF13193 AMP-binding enzyme C-terminal domain 482 559 2.0E-22 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AF_0840 291322968259fa6fd6dc95844c991ff3 577 SUPERFAMILY SSF56801 25 571 7.2E-157 T 31-10-2018 AF_0840 291322968259fa6fd6dc95844c991ff3 577 Pfam PF00501 AMP-binding enzyme 46 472 5.6E-106 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_0840 291322968259fa6fd6dc95844c991ff3 577 Gene3D G3DSA:3.40.50.980 63 389 6.8E-118 T 31-10-2018 AF_0840 291322968259fa6fd6dc95844c991ff3 577 Gene3D G3DSA:2.30.38.10 390 466 6.8E-118 T 31-10-2018 AF_0840 291322968259fa6fd6dc95844c991ff3 577 Gene3D G3DSA:3.40.50.980 68 243 6.8E-118 T 31-10-2018 AF_0840 291322968259fa6fd6dc95844c991ff3 577 Gene3D G3DSA:3.30.300.310 469 574 8.3E-36 T 31-10-2018 AF_1235 35c0b0852157b98de04dee3b519dc793 103 ProSitePatterns PS00466 Zinc finger TFIIS-type signature. 64 99 - T 31-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 AF_1235 35c0b0852157b98de04dee3b519dc793 103 PIRSF PIRSF005586 1 103 1.9E-32 T 31-10-2018 IPR012164 DNA-directed RNA polymerase subunit/transcription factor S GO:0006351 AF_1235 35c0b0852157b98de04dee3b519dc793 103 Gene3D G3DSA:2.20.25.10 3 35 9.5E-6 T 31-10-2018 AF_1235 35c0b0852157b98de04dee3b519dc793 103 Pfam PF01096 Transcription factor S-II (TFIIS) 63 100 1.2E-17 T 31-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 AF_1235 35c0b0852157b98de04dee3b519dc793 103 TIGRFAM TIGR01384 TFS_arch: transcription factor S 2 103 1.4E-32 T 31-10-2018 IPR006288 Transcription factor S GO:0006355 AF_1235 35c0b0852157b98de04dee3b519dc793 103 ProSitePatterns PS01030 RNA polymerases M / 15 Kd subunits signature. 3 23 - T 31-10-2018 IPR019761 DNA-directed RNA polymerase M, 15kDa subunit, conserved site AF_1235 35c0b0852157b98de04dee3b519dc793 103 Pfam PF02150 RNA polymerases M/15 Kd subunit 2 31 7.2E-14 T 31-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 AF_1235 35c0b0852157b98de04dee3b519dc793 103 SUPERFAMILY SSF57783 40 103 5.21E-22 T 31-10-2018 AF_1235 35c0b0852157b98de04dee3b519dc793 103 SMART SM00440 62 101 4.7E-18 T 31-10-2018 IPR001222 Zinc finger, TFIIS-type GO:0003676|GO:0006351|GO:0008270 AF_1235 35c0b0852157b98de04dee3b519dc793 103 SMART SM00661 2 49 6.1E-19 T 31-10-2018 IPR001529 DNA-directed RNA polymerase, M/15kDa subunit GO:0006351 AF_1235 35c0b0852157b98de04dee3b519dc793 103 Gene3D G3DSA:2.20.25.10 49 103 2.7E-23 T 31-10-2018 AF_0465 85b7198e89290240317ba386ee98ac0e 786 Pfam PF00521 DNA gyrase/topoisomerase IV, subunit A 26 457 5.0E-165 T 31-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AF_0465 85b7198e89290240317ba386ee98ac0e 786 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 639 682 1.2E-13 T 31-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AF_0465 85b7198e89290240317ba386ee98ac0e 786 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 604 639 2.0 T 31-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AF_0465 85b7198e89290240317ba386ee98ac0e 786 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 688 736 1.5E-11 T 31-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AF_0465 85b7198e89290240317ba386ee98ac0e 786 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 541 588 2.4E-9 T 31-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AF_0465 85b7198e89290240317ba386ee98ac0e 786 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 494 532 1.8E-10 T 31-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AF_0465 85b7198e89290240317ba386ee98ac0e 786 Pfam PF03989 DNA gyrase C-terminal domain, beta-propeller 739 769 2.1E-5 T 31-10-2018 IPR006691 DNA gyrase/topoisomerase IV, subunit A, C-terminal repeat GO:0003677|GO:0003916|GO:0005524|GO:0005694|GO:0006265 AF_0465 85b7198e89290240317ba386ee98ac0e 786 Gene3D G3DSA:3.90.199.10 26 473 2.2E-211 T 31-10-2018 IPR013758 DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-beta GO:0003677|GO:0003918|GO:0005524|GO:0006259|GO:0006265 Reactome: R-HSA-4615885 AF_0465 85b7198e89290240317ba386ee98ac0e 786 SMART SM00434 5 452 5.3E-285 T 31-10-2018 IPR002205 DNA topoisomerase, type IIA, subunit A/C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AF_0465 85b7198e89290240317ba386ee98ac0e 786 Gene3D G3DSA:2.120.10.90 484 782 2.1E-80 T 31-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal AF_0465 85b7198e89290240317ba386ee98ac0e 786 SUPERFAMILY SSF56719 24 475 2.35E-177 T 31-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AF_0465 85b7198e89290240317ba386ee98ac0e 786 SUPERFAMILY SSF101904 486 771 2.75E-71 T 31-10-2018 IPR035516 DNA gyrase/topoisomerase IV, subunit A, C-terminal AF_0465 85b7198e89290240317ba386ee98ac0e 786 Gene3D G3DSA:1.10.268.10 357 446 2.2E-211 T 31-10-2018 IPR013757 Type IIA DNA topoisomerase subunit A, alpha-helical domain superfamily GO:0003677|GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AF_0465 85b7198e89290240317ba386ee98ac0e 786 Gene3D G3DSA:3.30.1360.40 230 320 2.2E-211 T 31-10-2018 AF_0465 85b7198e89290240317ba386ee98ac0e 786 TIGRFAM TIGR01063 gyrA: DNA gyrase, A subunit 6 771 0.0 T 31-10-2018 AF_2219 07970d0f9fa617772ddc91c028a3a245 144 TIGRFAM TIGR00640 acid_CoA_mut_C: methylmalonyl-CoA mutase C-terminal domain 10 143 3.3E-62 T 31-10-2018 IPR006159 Methylmalonyl-CoA mutase, C-terminal GO:0016853 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AF_2219 07970d0f9fa617772ddc91c028a3a245 144 Pfam PF02310 B12 binding domain 12 126 9.1E-24 T 31-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AF_2219 07970d0f9fa617772ddc91c028a3a245 144 Gene3D G3DSA:3.40.50.280 2 144 2.8E-60 T 31-10-2018 AF_2219 07970d0f9fa617772ddc91c028a3a245 144 SUPERFAMILY SSF52242 5 138 6.28E-51 T 31-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 AF_2015 34eac3a00a9824521366108ff4eb69d5 543 Gene3D G3DSA:3.40.50.1220 185 337 6.3E-34 T 31-10-2018 AF_2015 34eac3a00a9824521366108ff4eb69d5 543 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 192 311 9.1E-27 T 31-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AF_2015 34eac3a00a9824521366108ff4eb69d5 543 SUPERFAMILY SSF52467 187 359 7.12E-37 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AF_2015 34eac3a00a9824521366108ff4eb69d5 543 SUPERFAMILY SSF52518 352 534 5.14E-42 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold AF_2015 34eac3a00a9824521366108ff4eb69d5 543 SUPERFAMILY SSF52518 1 173 1.64E-44 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold AF_2015 34eac3a00a9824521366108ff4eb69d5 543 Gene3D G3DSA:3.40.50.970 338 534 9.1E-48 T 31-10-2018 AF_2015 34eac3a00a9824521366108ff4eb69d5 543 Gene3D G3DSA:3.40.50.970 1 175 6.7E-53 T 31-10-2018 AF_2015 34eac3a00a9824521366108ff4eb69d5 543 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 375 524 2.3E-28 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AF_2015 34eac3a00a9824521366108ff4eb69d5 543 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 167 2.4E-50 T 31-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AF_2015 34eac3a00a9824521366108ff4eb69d5 543 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 410 429 - T 31-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 AF_0822 9240d5b0a4fba36cb5b976e31c4b241d 238 SMART SM00382 30 232 9.9E-10 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0822 9240d5b0a4fba36cb5b976e31c4b241d 238 Pfam PF00005 ABC transporter 21 167 1.4E-32 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0822 9240d5b0a4fba36cb5b976e31c4b241d 238 SUPERFAMILY SSF52540 5 236 1.81E-61 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0822 9240d5b0a4fba36cb5b976e31c4b241d 238 Gene3D G3DSA:3.40.50.300 2 238 2.4E-64 T 31-10-2018 AF_0822 9240d5b0a4fba36cb5b976e31c4b241d 238 ProSitePatterns PS00211 ABC transporters family signature. 140 154 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_0822 9240d5b0a4fba36cb5b976e31c4b241d 238 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 219 237 1.4E-5 T 31-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AF_0470 80b6cbdc40950abb6c7f94b40a15460d 67 Pfam PF00037 4Fe-4S binding domain 4 25 3.5E-6 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0470 80b6cbdc40950abb6c7f94b40a15460d 67 Pfam PF00037 4Fe-4S binding domain 37 54 1.4E-4 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0470 80b6cbdc40950abb6c7f94b40a15460d 67 SUPERFAMILY SSF54862 3 55 3.72E-13 T 31-10-2018 AF_0470 80b6cbdc40950abb6c7f94b40a15460d 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 38 49 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0470 80b6cbdc40950abb6c7f94b40a15460d 67 Gene3D G3DSA:3.30.70.20 6 53 4.6E-9 T 31-10-2018 AF_0470 80b6cbdc40950abb6c7f94b40a15460d 67 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 11 22 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0817 2190349f7e1be9fa9ebd1b533e6b5c98 619 PIRSF PIRSF006425 1 619 0.0 T 31-10-2018 IPR014441 Uncharacterised conserved protein UCP006425, beta-propeller-type AF_0817 2190349f7e1be9fa9ebd1b533e6b5c98 619 SUPERFAMILY SSF50998 167 616 1.12E-12 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AF_0817 2190349f7e1be9fa9ebd1b533e6b5c98 619 Pfam PF09826 Beta propeller domain 95 608 2.3E-108 T 31-10-2018 IPR019198 Beta propeller domain-containing family AF_0919 3404bd3384d03ad44c2866403dce300c 151 Gene3D G3DSA:3.60.21.10 1 149 1.0E-32 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like AF_0919 3404bd3384d03ad44c2866403dce300c 151 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 1 149 1.7E-40 T 31-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 AF_0919 3404bd3384d03ad44c2866403dce300c 151 SUPERFAMILY SSF56300 1 143 1.12E-24 T 31-10-2018 AF_0919 3404bd3384d03ad44c2866403dce300c 151 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 1 142 4.3E-24 T 31-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 AF_0192 d3288b273f5f4f545adde8f1ae121136 75 SUPERFAMILY SSF56784 10 59 8.14E-5 T 31-10-2018 IPR036412 HAD-like superfamily AF_0192 d3288b273f5f4f545adde8f1ae121136 75 Gene3D G3DSA:3.40.50.1000 8 67 2.3E-9 T 31-10-2018 IPR023214 HAD superfamily AF_0192 d3288b273f5f4f545adde8f1ae121136 75 Pfam PF00702 haloacid dehalogenase-like hydrolase 11 61 3.7E-7 T 31-10-2018 AF_1358 0436a4c603be657fd9ecb89db3f0aab2 283 SUPERFAMILY SSF161098 12 275 9.55E-33 T 31-10-2018 IPR035906 MetI-like superfamily AF_1358 0436a4c603be657fd9ecb89db3f0aab2 283 TIGRFAM TIGR00974 3a0107s02c: phosphate ABC transporter, permease protein PstA 10 279 1.5E-76 T 31-10-2018 IPR005672 Phosphate transport system permease protein PstA GO:0005315|GO:0005887|GO:0035435 AF_1358 0436a4c603be657fd9ecb89db3f0aab2 283 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 81 282 6.0E-22 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AF_1358 0436a4c603be657fd9ecb89db3f0aab2 283 Gene3D G3DSA:1.10.3720.10 55 281 7.1E-31 T 31-10-2018 IPR035906 MetI-like superfamily AF_0017 1db99aefd939142feb7f34b1733e4283 661 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 8 187 2.7E-65 T 31-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_0017 1db99aefd939142feb7f34b1733e4283 661 Gene3D G3DSA:1.10.1040.10 192 300 1.1E-29 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AF_0017 1db99aefd939142feb7f34b1733e4283 661 SUPERFAMILY SSF51735 5 186 1.27E-57 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0017 1db99aefd939142feb7f34b1733e4283 661 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 502 522 - T 31-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 AF_0017 1db99aefd939142feb7f34b1733e4283 661 SUPERFAMILY SSF52096 404 661 9.19E-85 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AF_0017 1db99aefd939142feb7f34b1733e4283 661 Gene3D G3DSA:1.10.1040.10 310 401 1.3E-25 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AF_0017 1db99aefd939142feb7f34b1733e4283 661 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 11 28 2.4E-7 T 31-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AF_0017 1db99aefd939142feb7f34b1733e4283 661 PRINTS PR00077 NAD-dependent glycerol-3-phosphate dehydrogenase signature 70 97 2.4E-7 T 31-10-2018 IPR006168 Glycerol-3-phosphate dehydrogenase, NAD-dependent GO:0004367|GO:0006072|GO:0009331|GO:0055114 KEGG: 00564+1.1.1.94|MetaCyc: PWY-5667|MetaCyc: PWY-5981|MetaCyc: PWY-7902|Reactome: R-HSA-1483166 AF_0017 1db99aefd939142feb7f34b1733e4283 661 Gene3D G3DSA:3.90.226.10 402 661 1.8E-86 T 31-10-2018 AF_0017 1db99aefd939142feb7f34b1733e4283 661 SUPERFAMILY SSF48179 189 295 3.32E-27 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_0017 1db99aefd939142feb7f34b1733e4283 661 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 190 288 6.1E-29 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_0017 1db99aefd939142feb7f34b1733e4283 661 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 308 400 7.5E-22 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_0017 1db99aefd939142feb7f34b1733e4283 661 Gene3D G3DSA:3.40.50.720 2 191 4.5E-69 T 31-10-2018 AF_0017 1db99aefd939142feb7f34b1733e4283 661 Pfam PF00378 Enoyl-CoA hydratase/isomerase 412 660 3.6E-62 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AF_0017 1db99aefd939142feb7f34b1733e4283 661 SUPERFAMILY SSF48179 304 413 7.23E-28 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_2154 1cfca7ac65ce5017b9a9a390cca52f23 163 Pfam PF03684 Uncharacterised protein family (UPF0179) 19 156 4.4E-50 T 31-10-2018 IPR005369 Uncharacterised protein family UPF0179 AF_2154 1cfca7ac65ce5017b9a9a390cca52f23 163 ProDom PD016182 UPF0179 TK0790 TV1250 PAE0681 PF1381 AF2154 MA3685 VNG1401C MJ1627 PH1477 18 142 1.0E-66 T 31-10-2018 IPR005369 Uncharacterised protein family UPF0179 AF_2154 1cfca7ac65ce5017b9a9a390cca52f23 163 Hamap MF_00498 UPF0179 protein . 17 160 26.577 T 31-10-2018 IPR005369 Uncharacterised protein family UPF0179 AF_2154 1cfca7ac65ce5017b9a9a390cca52f23 163 PIRSF PIRSF006595 16 163 2.2E-54 T 31-10-2018 IPR005369 Uncharacterised protein family UPF0179 AF_0536 a07fd9d060393dae4a81a53fb10311cb 66 TIGRFAM TIGR00327 secE_euk_arch: protein translocase SEC61 complex gamma subunit, archaeal and eukaryotic 6 66 8.4E-32 T 31-10-2018 IPR008158 Protein translocase SEC61 complex, gamma subunit GO:0015031|GO:0015450|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AF_0536 a07fd9d060393dae4a81a53fb10311cb 66 Hamap MF_00422 Protein translocase subunit SecE [secE]. 9 64 11.987 T 31-10-2018 IPR001901 Protein translocase complex, SecE/Sec61-gamma subunit GO:0006605|GO:0006886|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AF_0536 a07fd9d060393dae4a81a53fb10311cb 66 Gene3D G3DSA:1.20.5.820 3 66 9.4E-17 T 31-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AF_0536 a07fd9d060393dae4a81a53fb10311cb 66 SUPERFAMILY SSF103456 7 62 9.42E-15 T 31-10-2018 IPR023391 Protein translocase SecE domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AF_1467 4a51fc8413b70c800a8a88a92fafcda4 222 SMART SM00387 113 219 7.1E-28 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_1467 4a51fc8413b70c800a8a88a92fafcda4 222 PRINTS PR00344 Bacterial sensor protein C-terminal signature 179 197 1.8E-11 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1467 4a51fc8413b70c800a8a88a92fafcda4 222 PRINTS PR00344 Bacterial sensor protein C-terminal signature 149 163 1.8E-11 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1467 4a51fc8413b70c800a8a88a92fafcda4 222 PRINTS PR00344 Bacterial sensor protein C-terminal signature 203 216 1.8E-11 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1467 4a51fc8413b70c800a8a88a92fafcda4 222 PRINTS PR00344 Bacterial sensor protein C-terminal signature 167 177 1.8E-11 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1467 4a51fc8413b70c800a8a88a92fafcda4 222 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 115 216 8.8E-18 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_1467 4a51fc8413b70c800a8a88a92fafcda4 222 Gene3D G3DSA:3.30.565.10 86 219 1.2E-29 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_1467 4a51fc8413b70c800a8a88a92fafcda4 222 SUPERFAMILY SSF55874 90 216 1.7E-29 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_2040 eaa08bc7314499aa784e08dc6545612f 396 Pfam PF01970 Tripartite tricarboxylate transporter TctA family 5 381 1.8E-51 T 31-10-2018 IPR002823 Protein of unknown function DUF112, transmembrane AF_1117 63343d383543fe25d62b2a4aa295da52 189 TIGRFAM TIGR00448 rpoE: DNA-directed RNA polymerase 1 179 3.5E-91 T 31-10-2018 IPR004519 DNA-directed RNA polymerase, subunit E/RPC8 GO:0003677|GO:0003899|GO:0006351 Reactome: R-HSA-1834949|Reactome: R-HSA-73780|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071 AF_1117 63343d383543fe25d62b2a4aa295da52 189 Pfam PF03876 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 8 77 6.9E-19 T 31-10-2018 IPR005576 RNA polymerase Rpb7, N-terminal GO:0003899|GO:0006351 AF_1117 63343d383543fe25d62b2a4aa295da52 189 SUPERFAMILY SSF50249 83 180 9.29E-24 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_1117 63343d383543fe25d62b2a4aa295da52 189 Pfam PF00575 S1 RNA binding domain 83 147 1.1E-13 T 31-10-2018 IPR003029 S1 domain GO:0003676 AF_1117 63343d383543fe25d62b2a4aa295da52 189 Gene3D G3DSA:2.40.50.140 82 188 3.6E-28 T 31-10-2018 AF_1117 63343d383543fe25d62b2a4aa295da52 189 SMART SM00316 80 166 3.5E-14 T 31-10-2018 IPR022967 RNA-binding domain, S1 AF_1117 63343d383543fe25d62b2a4aa295da52 189 SUPERFAMILY SSF88798 1 78 3.92E-22 T 31-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 AF_1117 63343d383543fe25d62b2a4aa295da52 189 Gene3D G3DSA:3.30.1490.120 1 80 2.2E-28 T 31-10-2018 IPR036898 RNA polymerase Rpb7-like, N-terminal domain superfamily GO:0003899|GO:0006351 AF_0263 35227a224a16e6f09c1668b641c3c36c 490 Gene3D G3DSA:3.90.550.10 55 286 1.7E-70 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0263 35227a224a16e6f09c1668b641c3c36c 490 Pfam PF12804 MobA-like NTP transferase domain 75 180 3.6E-17 T 31-10-2018 IPR025877 MobA-like NTP transferase AF_0263 35227a224a16e6f09c1668b641c3c36c 490 SUPERFAMILY SSF53448 73 288 2.7E-33 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0263 35227a224a16e6f09c1668b641c3c36c 490 Gene3D G3DSA:1.20.120.1760 295 489 1.5E-79 T 31-10-2018 AF_0263 35227a224a16e6f09c1668b641c3c36c 490 Pfam PF01066 CDP-alcohol phosphatidyltransferase 321 382 4.1E-8 T 31-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AF_0263 35227a224a16e6f09c1668b641c3c36c 490 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 360 382 - T 31-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AF_1747 475fd1d3bf7a1a6119ad176dc8a4b1dd 112 Gene3D G3DSA:3.30.70.120 1 112 9.1E-48 T 31-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AF_1747 475fd1d3bf7a1a6119ad176dc8a4b1dd 112 Pfam PF00543 Nitrogen regulatory protein P-II 4 105 2.7E-37 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AF_1747 475fd1d3bf7a1a6119ad176dc8a4b1dd 112 PRINTS PR00340 P-II protein signature 2 17 2.4E-36 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AF_1747 475fd1d3bf7a1a6119ad176dc8a4b1dd 112 PRINTS PR00340 P-II protein signature 83 103 2.4E-36 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AF_1747 475fd1d3bf7a1a6119ad176dc8a4b1dd 112 PRINTS PR00340 P-II protein signature 23 41 2.4E-36 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AF_1747 475fd1d3bf7a1a6119ad176dc8a4b1dd 112 PRINTS PR00340 P-II protein signature 52 75 2.4E-36 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AF_1747 475fd1d3bf7a1a6119ad176dc8a4b1dd 112 SMART SM00938 4 105 1.5E-53 T 31-10-2018 IPR002187 Nitrogen regulatory protein PII GO:0006808|GO:0030234 AF_1747 475fd1d3bf7a1a6119ad176dc8a4b1dd 112 SUPERFAMILY SSF54913 1 112 4.13E-41 T 31-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta AF_1747 475fd1d3bf7a1a6119ad176dc8a4b1dd 112 ProSitePatterns PS00638 P-II protein C-terminal region signature. 83 96 - T 31-10-2018 IPR017918 Nitrogen regulatory protein PII, conserved site GO:0006808|GO:0030234 AF_1349 ca54220d492a1d0cdb2daaaaf9c0309f 73 Gene3D G3DSA:2.20.28.10 20 73 7.6E-30 T 31-10-2018 AF_1349 ca54220d492a1d0cdb2daaaaf9c0309f 73 ProSitePatterns PS00202 Rubredoxin signature. 52 62 - T 31-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 AF_1349 ca54220d492a1d0cdb2daaaaf9c0309f 73 PRINTS PR00163 Rubredoxin signature 52 68 9.0E-14 T 31-10-2018 IPR024935 Rubredoxin domain GO:0005506 AF_1349 ca54220d492a1d0cdb2daaaaf9c0309f 73 PRINTS PR00163 Rubredoxin signature 22 38 9.0E-14 T 31-10-2018 IPR024935 Rubredoxin domain GO:0005506 AF_1349 ca54220d492a1d0cdb2daaaaf9c0309f 73 Pfam PF00301 Rubredoxin 22 68 2.1E-26 T 31-10-2018 IPR024935 Rubredoxin domain GO:0005506 AF_1349 ca54220d492a1d0cdb2daaaaf9c0309f 73 PIRSF PIRSF000071 19 73 2.0E-29 T 31-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 AF_1349 ca54220d492a1d0cdb2daaaaf9c0309f 73 SUPERFAMILY SSF57802 19 72 5.89E-25 T 31-10-2018 AF_1451 14bf0ccdc943cf68e6c95529cae1a207 545 ProSitePatterns PS00995 Chaperonins TCP-1 signature 3. 89 97 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AF_1451 14bf0ccdc943cf68e6c95529cae1a207 545 SUPERFAMILY SSF54849 150 405 4.27E-28 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily AF_1451 14bf0ccdc943cf68e6c95529cae1a207 545 SUPERFAMILY SSF52029 212 378 7.74E-62 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily AF_1451 14bf0ccdc943cf68e6c95529cae1a207 545 Gene3D G3DSA:1.10.560.10 28 522 2.1E-211 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily AF_1451 14bf0ccdc943cf68e6c95529cae1a207 545 ProSitePatterns PS00750 Chaperonins TCP-1 signature 1. 40 52 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AF_1451 14bf0ccdc943cf68e6c95529cae1a207 545 Gene3D G3DSA:3.50.7.10 218 369 2.1E-211 T 31-10-2018 IPR027409 GroEL-like apical domain superfamily AF_1451 14bf0ccdc943cf68e6c95529cae1a207 545 Gene3D G3DSA:3.30.260.10 147 405 2.1E-211 T 31-10-2018 IPR027410 TCP-1-like chaperonin intermediate domain superfamily AF_1451 14bf0ccdc943cf68e6c95529cae1a207 545 ProSitePatterns PS00751 Chaperonins TCP-1 signature 2. 61 77 - T 31-10-2018 IPR002194 Chaperonin TCP-1, conserved site GO:0005524|GO:0006457|GO:0051082 Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AF_1451 14bf0ccdc943cf68e6c95529cae1a207 545 SUPERFAMILY SSF48592 17 524 2.88E-97 T 31-10-2018 IPR027413 GroEL-like equatorial domain superfamily AF_1451 14bf0ccdc943cf68e6c95529cae1a207 545 Pfam PF00118 TCP-1/cpn60 chaperonin family 35 525 3.8E-188 T 31-10-2018 IPR002423 Chaperonin Cpn60/TCP-1 family GO:0005524 AF_1451 14bf0ccdc943cf68e6c95529cae1a207 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 37 53 1.7E-35 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AF_1451 14bf0ccdc943cf68e6c95529cae1a207 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 373 395 1.7E-35 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AF_1451 14bf0ccdc943cf68e6c95529cae1a207 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 89 108 1.7E-35 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AF_1451 14bf0ccdc943cf68e6c95529cae1a207 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 407 419 1.7E-35 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AF_1451 14bf0ccdc943cf68e6c95529cae1a207 545 PRINTS PR00304 Tailless complex polypeptide 1 (chaperone) signature 59 77 1.7E-35 T 31-10-2018 IPR017998 Chaperone tailless complex polypeptide 1 (TCP-1) Reactome: R-HSA-389957|Reactome: R-HSA-389960|Reactome: R-HSA-390450|Reactome: R-HSA-390471|Reactome: R-HSA-6814122 AF_1451 14bf0ccdc943cf68e6c95529cae1a207 545 TIGRFAM TIGR02339 thermosome_arch: thermosome, various subunits, archaeal 8 525 5.9E-249 T 31-10-2018 IPR012714 Thermosome, archaeal GO:0005524|GO:0006457|GO:0051082 AF_2042 f3a10215442befad3e4e4bc952cbfe54 219 Gene3D G3DSA:3.40.1160.10 1 219 1.2E-66 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AF_2042 f3a10215442befad3e4e4bc952cbfe54 219 TIGRFAM TIGR02076 pyrH_arch: putative uridylate kinase 3 218 2.3E-91 T 31-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 AF_2042 f3a10215442befad3e4e4bc952cbfe54 219 PIRSF PIRSF005650 1 219 1.3E-59 T 31-10-2018 IPR011817 Uridylate kinase GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 AF_2042 f3a10215442befad3e4e4bc952cbfe54 219 Pfam PF00696 Amino acid kinase family 1 198 7.6E-30 T 31-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AF_2042 f3a10215442befad3e4e4bc952cbfe54 219 Hamap MF_01220_A Uridylate kinase [pyrH]. 1 219 34.453 T 31-10-2018 IPR011818 Uridylate kinase, archaeal/spirochete, putative GO:0006221|GO:0009041 KEGG: 00240+2.7.4.22 AF_2042 f3a10215442befad3e4e4bc952cbfe54 219 SUPERFAMILY SSF53633 1 218 7.72E-42 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AF_1967 64ac4232be263be99afb79aeb21ed9d7 334 SUPERFAMILY SSF81301 77 149 8.88E-5 T 31-10-2018 AF_1967 64ac4232be263be99afb79aeb21ed9d7 334 Pfam PF01909 Nucleotidyltransferase domain 102 190 3.4E-7 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AF_1890 11f8f0a6902c9691db5950bd7bc83fc8 86 SUPERFAMILY SSF55315 4 84 6.06E-23 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like AF_1890 11f8f0a6902c9691db5950bd7bc83fc8 86 Gene3D G3DSA:3.30.1330.30 1 86 2.8E-28 T 31-10-2018 IPR029064 50S ribosomal protein L30e-like AF_1890 11f8f0a6902c9691db5950bd7bc83fc8 86 ProSitePatterns PS00709 Ribosomal protein L30e signature 1. 14 38 - T 31-10-2018 IPR022991 Ribosomal protein L30e, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1890 11f8f0a6902c9691db5950bd7bc83fc8 86 Pfam PF01248 Ribosomal protein L7Ae/L30e/S12e/Gadd45 family 3 85 4.3E-17 T 31-10-2018 IPR004038 Ribosomal protein L7Ae/L30e/S12e/Gadd45 AF_1890 11f8f0a6902c9691db5950bd7bc83fc8 86 Hamap MF_00481 50S ribosomal protein L30e [rpl30e]. 2 85 21.148 T 31-10-2018 IPR000231 Ribosomal protein L30e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0038 e154c782236592e4e41abcc55f755494 361 SUPERFAMILY SSF53756 1 351 2.78E-65 T 31-10-2018 AF_0038 e154c782236592e4e41abcc55f755494 361 Pfam PF00534 Glycosyl transferases group 1 185 334 9.9E-34 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 AF_0038 e154c782236592e4e41abcc55f755494 361 Gene3D G3DSA:3.40.50.2000 186 341 1.4E-33 T 31-10-2018 AF_0038 e154c782236592e4e41abcc55f755494 361 Gene3D G3DSA:3.40.50.2000 1 185 7.8E-19 T 31-10-2018 AF_0038 e154c782236592e4e41abcc55f755494 361 Pfam PF13439 Glycosyltransferase Family 4 16 175 1.7E-17 T 31-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AF_2024 2a75d8226ccc04fdf10d02128a275a23 342 Gene3D G3DSA:3.90.1150.10 25 340 3.1E-100 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AF_2024 2a75d8226ccc04fdf10d02128a275a23 342 SUPERFAMILY SSF53383 21 342 1.28E-80 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AF_2024 2a75d8226ccc04fdf10d02128a275a23 342 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 2 342 5.7E-119 T 31-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AF_2024 2a75d8226ccc04fdf10d02128a275a23 342 Gene3D G3DSA:3.40.640.10 37 251 3.1E-100 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AF_2024 2a75d8226ccc04fdf10d02128a275a23 342 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 1 342 52.829 T 31-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AF_2024 2a75d8226ccc04fdf10d02128a275a23 342 Pfam PF00155 Aminotransferase class I and II 24 339 1.6E-49 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AF_2024 2a75d8226ccc04fdf10d02128a275a23 342 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 203 216 - T 31-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AF_1345 affe3bcf80b85c46ae16d602c5763ae5 102 SUPERFAMILY SSF102891 3 102 1.7E-33 T 31-10-2018 IPR036493 Hypothetical protein YunC superfamily AF_1345 affe3bcf80b85c46ae16d602c5763ae5 102 Gene3D G3DSA:3.30.1980.10 2 102 1.1E-31 T 31-10-2018 IPR036493 Hypothetical protein YunC superfamily AF_1345 affe3bcf80b85c46ae16d602c5763ae5 102 Pfam PF08827 Domain of unknown function (DUF1805) 44 102 1.1E-20 T 31-10-2018 IPR014931 Protein of unknown function DUF1805 AF_0474 33f515ba36d04cd7189a692139e36c36 180 ProSitePatterns PS00519 AsnC-type HTH domain signature. 21 47 - T 31-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site AF_0474 33f515ba36d04cd7189a692139e36c36 180 Pfam PF08394 Archaeal TRASH domain 141 176 7.4E-19 T 31-10-2018 IPR013603 TRASH transcription regulator C-terminal, archaeal AF_0474 33f515ba36d04cd7189a692139e36c36 180 SUPERFAMILY SSF46785 2 56 2.26E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0474 33f515ba36d04cd7189a692139e36c36 180 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 19 30 2.1E-14 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_0474 33f515ba36d04cd7189a692139e36c36 180 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 30 49 2.1E-14 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_0474 33f515ba36d04cd7189a692139e36c36 180 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 3 19 2.1E-14 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_0474 33f515ba36d04cd7189a692139e36c36 180 SMART SM00746 141 177 6.2E-8 T 31-10-2018 IPR011017 TRASH domain AF_0474 33f515ba36d04cd7189a692139e36c36 180 Gene3D G3DSA:1.10.10.10 1 54 4.7E-22 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0474 33f515ba36d04cd7189a692139e36c36 180 Pfam PF13412 Winged helix-turn-helix DNA-binding 3 50 3.7E-17 T 31-10-2018 AF_0474 33f515ba36d04cd7189a692139e36c36 180 SMART SM00344 3 110 9.3E-31 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AF_2019 d823f1ee37a9d26d1cd30fefbb40b7f6 371 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 153 181 - T 31-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 AF_2019 d823f1ee37a9d26d1cd30fefbb40b7f6 371 SUPERFAMILY SSF56796 2 364 3.53E-102 T 31-10-2018 AF_2019 d823f1ee37a9d26d1cd30fefbb40b7f6 371 Pfam PF00465 Iron-containing alcohol dehydrogenase 2 354 6.8E-103 T 31-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 AF_2019 d823f1ee37a9d26d1cd30fefbb40b7f6 371 Gene3D G3DSA:3.40.50.1970 1 164 6.3E-42 T 31-10-2018 AF_2019 d823f1ee37a9d26d1cd30fefbb40b7f6 371 Gene3D G3DSA:1.20.1090.10 165 362 1.6E-61 T 31-10-2018 AF_2272 258c6774a3456a5c51268d1434b2e5cf 240 Gene3D G3DSA:3.50.50.60 106 202 8.8E-16 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_2272 258c6774a3456a5c51268d1434b2e5cf 240 Gene3D G3DSA:3.50.50.60 5 207 8.8E-16 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_2272 258c6774a3456a5c51268d1434b2e5cf 240 SUPERFAMILY SSF51905 5 210 5.18E-19 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_2272 258c6774a3456a5c51268d1434b2e5cf 240 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 5 129 1.8E-9 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AF_0109 1c9cfce9d4f44e63303e4995e5e550a9 107 Hamap MF_00757 Ribonuclease P protein component 4 [rnp4]. 5 100 23.372 T 31-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 AF_0109 1c9cfce9d4f44e63303e4995e5e550a9 107 PIRSF PIRSF004878 2 107 6.3E-35 T 31-10-2018 IPR016432 Ribonuclease P, protein component 4 GO:0001682|GO:0004526 AF_0109 1c9cfce9d4f44e63303e4995e5e550a9 107 Gene3D G3DSA:1.20.5.420 2 58 2.4E-17 T 31-10-2018 AF_0109 1c9cfce9d4f44e63303e4995e5e550a9 107 Gene3D G3DSA:2.20.25.200 59 107 1.6E-7 T 31-10-2018 AF_0109 1c9cfce9d4f44e63303e4995e5e550a9 107 Pfam PF04032 RNAse P Rpr2/Rpp21/SNM1 subunit domain 19 91 5.0E-9 T 31-10-2018 IPR007175 RNAse P, Rpr2/Rpp21 subunit Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AF_2065 359622d7fcf7243f3f19191ba28c4912 215 Pfam PF01912 eIF-6 family 2 195 7.0E-61 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 AF_2065 359622d7fcf7243f3f19191ba28c4912 215 SMART SM00654 1 195 1.8E-95 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 AF_2065 359622d7fcf7243f3f19191ba28c4912 215 Hamap MF_00032 Translation initiation factor 6 [eif6]. 1 215 70.904 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 AF_2065 359622d7fcf7243f3f19191ba28c4912 215 SUPERFAMILY SSF55909 2 213 3.24E-61 T 31-10-2018 AF_2065 359622d7fcf7243f3f19191ba28c4912 215 Gene3D G3DSA:3.75.10.10 1 214 7.9E-65 T 31-10-2018 AF_2065 359622d7fcf7243f3f19191ba28c4912 215 TIGRFAM TIGR00323 eIF-6: putative translation initiation factor eIF-6 2 214 1.9E-97 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 AF_2065 359622d7fcf7243f3f19191ba28c4912 215 PIRSF PIRSF006413 1 215 2.2E-73 T 31-10-2018 IPR002769 Translation initiation factor IF6 GO:0042256|GO:0043022 AF_1462 7699165ca256ec3b354e6bb42817a2cd 183 Pfam PF01794 Ferric reductase like transmembrane component 3 124 4.4E-12 T 31-10-2018 IPR013130 Ferric reductase transmembrane component-like domain AF_1116 7e9dee0f0a14669945413927372ca630 62 ProDom PD019197 RNA DNA-DIRECTED POLYMERASE SUBUNIT E'' POLYMERASE RPOE2 TRANSFERASE NUCLEOTIDYLTRANSFERASE E 15 62 8.0E-22 T 31-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 AF_1116 7e9dee0f0a14669945413927372ca630 62 Gene3D G3DSA:2.20.28.90 1 62 4.8E-25 T 31-10-2018 IPR038589 Archaeal transcription elongation factor Spt4 superfamily AF_1116 7e9dee0f0a14669945413927372ca630 62 SMART SM01389 3 62 1.5E-26 T 31-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 AF_1116 7e9dee0f0a14669945413927372ca630 62 SUPERFAMILY SSF63393 4 61 1.33E-20 T 31-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 AF_1116 7e9dee0f0a14669945413927372ca630 62 Pfam PF06093 Spt4/RpoE2 zinc finger 4 61 1.9E-16 T 31-10-2018 IPR022800 Spt4/RpoE2 zinc finger Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 AF_1116 7e9dee0f0a14669945413927372ca630 62 Hamap MF_00949 Transcription elongation factor Spt4 [spt4]. 5 62 27.104 T 31-10-2018 IPR007178 Archaeal transcription elongation factor Spt4 GO:0006355 AF_1111 994e5a36a001697653f2123e1fe83009 103 Gene3D G3DSA:3.30.310.190 1 98 1.1E-29 T 31-10-2018 AF_1111 994e5a36a001697653f2123e1fe83009 103 PIRSF PIRSF022080 1 102 8.4E-42 T 31-10-2018 IPR016800 Uncharacterised conserved protein UCP022080 AF_2326 9259b72780f490161ef8925415e96902 137 Hamap MF_00232 Translation initiation factor 2 subunit beta [eif2b]. 3 137 32.986 T 31-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 AF_2326 9259b72780f490161ef8925415e96902 137 Pfam PF01873 Domain found in IF2B/IF5 22 131 5.9E-38 T 31-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 AF_2326 9259b72780f490161ef8925415e96902 137 TIGRFAM TIGR00311 aIF-2beta: putative translation initiation factor aIF-2, beta subunit 4 137 1.3E-72 T 31-10-2018 IPR004458 Translation initiation factor 2, beta subunit GO:0003743|GO:0006413 AF_2326 9259b72780f490161ef8925415e96902 137 Gene3D G3DSA:3.30.70.3150 35 125 4.2E-30 T 31-10-2018 AF_2326 9259b72780f490161ef8925415e96902 137 SMART SM00653 24 131 3.4E-58 T 31-10-2018 IPR002735 Translation initiation factor IF2/IF5 GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 AF_2326 9259b72780f490161ef8925415e96902 137 SUPERFAMILY SSF75689 101 137 9.29E-12 T 31-10-2018 IPR016190 Translation initiation factor IF2/IF5, zinc-binding GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 AF_2326 9259b72780f490161ef8925415e96902 137 SUPERFAMILY SSF100966 3 104 5.89E-28 T 31-10-2018 IPR016189 Translation initiation factor IF2/IF5, N-terminal GO:0003743|GO:0006413 Reactome: R-HSA-72702|Reactome: R-HSA-72706 AF_1960 39e6df67ebac39fc539003dd0b11b62a 453 Pfam PF13086 AAA domain 63 147 6.0E-11 T 31-10-2018 AF_1960 39e6df67ebac39fc539003dd0b11b62a 453 Pfam PF13086 AAA domain 158 232 2.0E-12 T 31-10-2018 AF_1960 39e6df67ebac39fc539003dd0b11b62a 453 SUPERFAMILY SSF52540 50 439 3.93E-50 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1960 39e6df67ebac39fc539003dd0b11b62a 453 Gene3D G3DSA:3.40.50.300 3 256 2.2E-36 T 31-10-2018 AF_1960 39e6df67ebac39fc539003dd0b11b62a 453 SMART SM00382 66 296 2.9E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1960 39e6df67ebac39fc539003dd0b11b62a 453 Gene3D G3DSA:3.40.50.300 263 451 4.9E-42 T 31-10-2018 AF_1960 39e6df67ebac39fc539003dd0b11b62a 453 Pfam PF13087 AAA domain 255 426 5.3E-34 T 31-10-2018 AF_2151 d74b13239a20e762b6fa5aa2f341dea4 175 Pfam PF00857 Isochorismatase family 3 170 6.6E-51 T 31-10-2018 IPR000868 Isochorismatase-like GO:0003824 AF_2151 d74b13239a20e762b6fa5aa2f341dea4 175 SUPERFAMILY SSF52499 3 174 2.22E-63 T 31-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AF_2151 d74b13239a20e762b6fa5aa2f341dea4 175 Gene3D G3DSA:3.40.50.850 1 175 3.2E-64 T 31-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AF_0716 634be99b147363704e90518fac5fbb3b 147 SUPERFAMILY SSF116726 74 136 7.06E-5 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AF_0344 4c4646333b383f253f86afdd2dea72b9 125 SUPERFAMILY SSF49367 3 121 2.88E-41 T 31-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 AF_0344 4c4646333b383f253f86afdd2dea72b9 125 Gene3D G3DSA:2.60.40.730 1 125 9.7E-51 T 31-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 AF_0344 4c4646333b383f253f86afdd2dea72b9 125 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 5 125 6.2E-51 T 31-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 AF_0344 4c4646333b383f253f86afdd2dea72b9 125 Pfam PF01880 Desulfoferrodoxin 7 118 1.0E-31 T 31-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 AF_1031 c45fe713d244fe6c8cfc64de6b7e7da0 443 Gene3D G3DSA:3.30.110.80 225 315 2.2E-92 T 31-10-2018 AF_1031 c45fe713d244fe6c8cfc64de6b7e7da0 443 SUPERFAMILY SSF56300 1 325 2.34E-56 T 31-10-2018 AF_1031 c45fe713d244fe6c8cfc64de6b7e7da0 443 Hamap MF_02044 DNA double-strand break repair protein Mre11 [mre11]. 1 402 24.402 T 31-10-2018 IPR032885 DNA double-strand break repair protein Mre11, archaea-type GO:0006302 AF_1031 c45fe713d244fe6c8cfc64de6b7e7da0 443 Gene3D G3DSA:3.60.21.10 1 266 2.2E-92 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like AF_1031 c45fe713d244fe6c8cfc64de6b7e7da0 443 Pfam PF00149 Calcineurin-like phosphoesterase 1 204 1.4E-16 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AF_2350 e223a1796f9903475dce1a29e46353f0 943 Gene3D G3DSA:3.40.50.10810 30 280 7.2E-47 T 31-10-2018 IPR038718 SNF2-like, N-terminal domain superfamily AF_2350 e223a1796f9903475dce1a29e46353f0 943 SUPERFAMILY SSF52540 149 530 1.89E-46 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2350 e223a1796f9903475dce1a29e46353f0 943 Gene3D G3DSA:3.40.50.300 318 525 5.9E-39 T 31-10-2018 AF_2350 e223a1796f9903475dce1a29e46353f0 943 SMART SM00490 412 494 1.1E-23 T 31-10-2018 IPR001650 Helicase, C-terminal AF_2350 e223a1796f9903475dce1a29e46353f0 943 SUPERFAMILY SSF52540 22 224 2.0E-31 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2350 e223a1796f9903475dce1a29e46353f0 943 Pfam PF04851 Type III restriction enzyme, res subunit 31 190 5.0E-15 T 31-10-2018 IPR006935 Helicase/UvrB, N-terminal GO:0003677|GO:0005524|GO:0016787 AF_2350 e223a1796f9903475dce1a29e46353f0 943 SMART SM00487 30 223 6.5E-21 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AF_2350 e223a1796f9903475dce1a29e46353f0 943 Pfam PF13020 Domain of unknown function (DUF3883) 890 938 3.1E-6 T 31-10-2018 IPR024975 Domain of unknown function DUF3883 AF_2350 e223a1796f9903475dce1a29e46353f0 943 Pfam PF00271 Helicase conserved C-terminal domain 383 494 1.7E-21 T 31-10-2018 IPR001650 Helicase, C-terminal AF_2084 28b798e23dbb7ef40d2ee8ff172a7d59 354 TIGRFAM TIGR01109 Na_pump_decarbB: sodium ion-translocating decarboxylase, beta subunit 3 348 4.6E-175 T 31-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 AF_2084 28b798e23dbb7ef40d2ee8ff172a7d59 354 Pfam PF03977 Na+-transporting oxaloacetate decarboxylase beta subunit 4 352 4.5E-156 T 31-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 AF_2084 28b798e23dbb7ef40d2ee8ff172a7d59 354 PIRSF PIRSF015658 1 354 1.4E-168 T 31-10-2018 IPR005661 Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit GO:0006814|GO:0016829 KEGG: 00620+4.1.1.3 AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 SMART SM00385 143 224 5.2E-14 T 31-10-2018 IPR013763 Cyclin-like AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 SMART SM00385 237 318 4.8E-14 T 31-10-2018 IPR013763 Cyclin-like AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 Gene3D G3DSA:1.10.472.170 29 226 6.6E-73 T 31-10-2018 AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 SUPERFAMILY SSF57783 27 73 1.42E-17 T 31-10-2018 AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 SUPERFAMILY SSF47954 234 324 3.61E-33 T 31-10-2018 IPR036915 Cyclin-like superfamily AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 Gene3D G3DSA:1.10.472.10 234 326 1.3E-29 T 31-10-2018 AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 177 192 - T 31-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 SUPERFAMILY SSF47954 137 231 2.75E-29 T 31-10-2018 IPR036915 Cyclin-like superfamily AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 Hamap MF_00383 Transcription initiation factor IIB [tfb]. 24 324 48.068 T 31-10-2018 IPR023484 Transcription initiation factor TFIIB, archaea AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 Pfam PF08271 TFIIB zinc-binding 29 70 2.7E-20 T 31-10-2018 IPR013137 Zinc finger, TFIIB-type AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 ProSitePatterns PS00782 Transcription factor TFIIB repeat signature. 271 286 - T 31-10-2018 IPR023486 Transcription factor TFIIB, conserved site Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-674695|Reactome: R-HSA-6807505|Reactome: R-HSA-73776|Reactome: R-HSA-73779|Reactome: R-HSA-75953|Reactome: R-HSA-76042 AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 PRINTS PR00685 Transcription initiation factor IIB signature 42 62 8.1E-69 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 PRINTS PR00685 Transcription initiation factor IIB signature 77 98 8.1E-69 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 PRINTS PR00685 Transcription initiation factor IIB signature 64 77 8.1E-69 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 PRINTS PR00685 Transcription initiation factor IIB signature 211 226 8.1E-69 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 PRINTS PR00685 Transcription initiation factor IIB signature 272 288 8.1E-69 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 PRINTS PR00685 Transcription initiation factor IIB signature 304 318 8.1E-69 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 PRINTS PR00685 Transcription initiation factor IIB signature 185 204 8.1E-69 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 PRINTS PR00685 Transcription initiation factor IIB signature 238 256 8.1E-69 T 31-10-2018 IPR000812 Transcription factor TFIIB GO:0006355|GO:0070897 AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 Pfam PF00382 Transcription factor TFIIB repeat 239 309 7.1E-22 T 31-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 AF_1299 bb61989bb36a358ea82f0eaebd71d888 326 Pfam PF00382 Transcription factor TFIIB repeat 146 215 1.0E-20 T 31-10-2018 IPR013150 Transcription factor TFIIB, cyclin-like domain GO:0017025 AF_1449 837aa5ef9657e93d21ddf54ed38810e5 776 Pfam PF01228 Glycine radical 656 758 1.3E-24 T 31-10-2018 IPR001150 Glycine radical domain GO:0003824 AF_1449 837aa5ef9657e93d21ddf54ed38810e5 776 Pfam PF02901 Pyruvate formate lyase-like 4 639 5.2E-201 T 31-10-2018 IPR004184 Pyruvate formate lyase domain GO:0003824 AF_1449 837aa5ef9657e93d21ddf54ed38810e5 776 Gene3D G3DSA:3.20.70.20 1 776 0.0 T 31-10-2018 AF_1449 837aa5ef9657e93d21ddf54ed38810e5 776 TIGRFAM TIGR01774 PFL2-3: glycyl radical enzyme, PFL2/glycerol dehydratase family 1 776 0.0 T 31-10-2018 IPR010098 Glycyl radical enzyme, PFL2/glycerol dehydratase family KEGG: 00620+2.3.1.54|KEGG: 00640+2.3.1.54|KEGG: 00650+2.3.1.54|MetaCyc: PWY-5480|MetaCyc: PWY-5485|MetaCyc: PWY-5493 AF_1449 837aa5ef9657e93d21ddf54ed38810e5 776 SUPERFAMILY SSF51998 15 773 1.46E-205 T 31-10-2018 AF_1417 b5a211284d6f28a1e8461aa2f7f7c39d 372 Gene3D G3DSA:3.90.1150.10 7 353 6.4E-128 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AF_1417 b5a211284d6f28a1e8461aa2f7f7c39d 372 ProSitePatterns PS00595 Aminotransferases class-V pyridoxal-phosphate attachment site. 174 194 - T 31-10-2018 IPR020578 Aminotransferase class-V, pyridoxal-phosphate binding site AF_1417 b5a211284d6f28a1e8461aa2f7f7c39d 372 PIRSF PIRSF000524 1 367 5.6E-128 T 31-10-2018 IPR024169 Serine-pyruvate aminotransferase/2-aminoethylphosphonate-pyruvate transaminase KEGG: 00440+2.6.1.37|MetaCyc: PWY-6832|Reactome: R-HSA-389661|Reactome: R-HSA-9033241 AF_1417 b5a211284d6f28a1e8461aa2f7f7c39d 372 Gene3D G3DSA:3.40.640.10 12 248 6.4E-128 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AF_1417 b5a211284d6f28a1e8461aa2f7f7c39d 372 SUPERFAMILY SSF53383 2 351 4.68E-99 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AF_1417 b5a211284d6f28a1e8461aa2f7f7c39d 372 Pfam PF00266 Aminotransferase class-V 3 341 2.2E-37 T 31-10-2018 IPR000192 Aminotransferase class V domain AF_2416 47e123da65ef1dabf0b8a498d2414cf7 384 Pfam PF02803 Thiolase, C-terminal domain 259 377 1.3E-9 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 AF_2416 47e123da65ef1dabf0b8a498d2414cf7 384 PIRSF PIRSF000429 1 383 2.7E-68 T 31-10-2018 IPR002155 Thiolase GO:0016747 AF_2416 47e123da65ef1dabf0b8a498d2414cf7 384 Gene3D G3DSA:3.40.47.10 3 384 6.2E-127 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_2416 47e123da65ef1dabf0b8a498d2414cf7 384 Pfam PF00108 Thiolase, N-terminal domain 4 224 7.4E-24 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AF_2416 47e123da65ef1dabf0b8a498d2414cf7 384 SUPERFAMILY SSF53901 231 381 2.5E-29 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_2416 47e123da65ef1dabf0b8a498d2414cf7 384 SUPERFAMILY SSF53901 4 228 9.2E-44 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0515 db73466c18a8430b751a413f234d01a8 294 SUPERFAMILY SSF52833 83 166 2.48E-15 T 31-10-2018 IPR036249 Thioredoxin-like superfamily AF_0515 db73466c18a8430b751a413f234d01a8 294 Gene3D G3DSA:3.40.30.80 3 156 1.6E-15 T 31-10-2018 AF_0515 db73466c18a8430b751a413f234d01a8 294 Pfam PF13192 Thioredoxin domain 95 163 1.5E-11 T 31-10-2018 IPR012336 Thioredoxin-like fold AF_0515 db73466c18a8430b751a413f234d01a8 294 SUPERFAMILY SSF48371 193 274 1.9E-6 T 31-10-2018 IPR016024 Armadillo-type fold AF_0515 db73466c18a8430b751a413f234d01a8 294 Gene3D G3DSA:1.25.10.10 157 293 9.7E-7 T 31-10-2018 IPR011989 Armadillo-like helical AF_0743 d101238435066619bbd6aaceae3fe42d 138 SUPERFAMILY SSF55021 55 132 6.64E-25 T 31-10-2018 AF_0743 d101238435066619bbd6aaceae3fe42d 138 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 45 4.4E-10 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 AF_0743 d101238435066619bbd6aaceae3fe42d 138 Hamap MF_00476 Nickel-responsive regulator [nikR]. 5 136 29.115 T 31-10-2018 IPR022988 Nickel-responsive transcriptional regulator NikR GO:0003677|GO:0006355|GO:0010045|GO:0016151 AF_0743 d101238435066619bbd6aaceae3fe42d 138 Pfam PF08753 NikR C terminal nickel binding domain 58 132 4.9E-29 T 31-10-2018 IPR014864 Transcription factor, NikR, nickel binding C-terminal AF_0743 d101238435066619bbd6aaceae3fe42d 138 Gene3D G3DSA:1.10.1220.10 12 48 9.2E-19 T 31-10-2018 IPR013321 Arc-type ribbon-helix-helix GO:0006355 AF_0743 d101238435066619bbd6aaceae3fe42d 138 SUPERFAMILY SSF47598 5 51 1.93E-14 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 AF_0743 d101238435066619bbd6aaceae3fe42d 138 Gene3D G3DSA:3.30.70.1150 49 137 3.1E-29 T 31-10-2018 IPR027271 Acetolactate synthase/Transcription factor NikR, C-terminal AF_0841 255a323d915c8c924256ac98f9886293 337 SUPERFAMILY SSF52540 2 332 1.59E-103 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0841 255a323d915c8c924256ac98f9886293 337 ProSitePatterns PS01266 Adenylosuccinate synthetase GTP-binding site. 10 17 - T 31-10-2018 IPR018220 Adenylosuccinate synthase, GTP-binding site GO:0005525 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AF_0841 255a323d915c8c924256ac98f9886293 337 Gene3D G3DSA:3.40.440.10 1 336 2.9E-127 T 31-10-2018 AF_0841 255a323d915c8c924256ac98f9886293 337 SMART SM00788 3 331 8.8E-158 T 31-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AF_0841 255a323d915c8c924256ac98f9886293 337 Hamap MF_00011 Adenylosuccinate synthetase [purA]. 1 337 96.352 T 31-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AF_0841 255a323d915c8c924256ac98f9886293 337 Pfam PF00709 Adenylosuccinate synthetase 289 330 1.7E-5 T 31-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AF_0841 255a323d915c8c924256ac98f9886293 337 Pfam PF00709 Adenylosuccinate synthetase 4 146 1.0E-35 T 31-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AF_0841 255a323d915c8c924256ac98f9886293 337 Pfam PF00709 Adenylosuccinate synthetase 148 287 9.1E-41 T 31-10-2018 IPR001114 Adenylosuccinate synthetase GO:0004019|GO:0005525|GO:0006164 KEGG: 00230+6.3.4.4|KEGG: 00250+6.3.4.4|MetaCyc: PWY-7219|Reactome: R-HSA-73817 AF_1770 5fc86d8f1e1ee07971006a31ccf98cac 313 ProSitePatterns PS00211 ABC transporters family signature. 152 166 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_1770 5fc86d8f1e1ee07971006a31ccf98cac 313 Pfam PF00005 ABC transporter 23 179 2.1E-31 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_1770 5fc86d8f1e1ee07971006a31ccf98cac 313 SUPERFAMILY SSF52540 3 249 6.41E-71 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1770 5fc86d8f1e1ee07971006a31ccf98cac 313 Pfam PF08352 Oligopeptide/dipeptide transporter, C-terminal region 230 293 2.1E-18 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AF_1770 5fc86d8f1e1ee07971006a31ccf98cac 313 SMART SM00382 32 228 2.5E-17 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1770 5fc86d8f1e1ee07971006a31ccf98cac 313 TIGRFAM TIGR01727 oligo_HPY: oligopeptide/dipeptide ABC transporter, ATP-binding protein, C-terminal domain 229 311 6.8E-24 T 31-10-2018 IPR013563 Oligopeptide/dipeptide ABC transporter, C-terminal GO:0000166|GO:0005524|GO:0015833 AF_1770 5fc86d8f1e1ee07971006a31ccf98cac 313 Gene3D G3DSA:3.40.50.300 1 313 3.8E-98 T 31-10-2018 AF_1055 3933f067ede8342f3ba2045196798083 207 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 13 34 9.1E-6 T 31-10-2018 IPR013373 Flagellin/pilin, N-terminal AF_1055 3933f067ede8342f3ba2045196798083 207 Pfam PF01917 Archaebacterial flagellin 14 194 4.7E-47 T 31-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 AF_0467 c1834bf1a3d83ac8e051a65b128fc179 355 Gene3D G3DSA:3.40.190.10 147 283 6.4E-89 T 31-10-2018 AF_0467 c1834bf1a3d83ac8e051a65b128fc179 355 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 17 346 4.8E-78 T 31-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family AF_0467 c1834bf1a3d83ac8e051a65b128fc179 355 Gene3D G3DSA:3.40.190.10 64 346 6.4E-89 T 31-10-2018 AF_0467 c1834bf1a3d83ac8e051a65b128fc179 355 SUPERFAMILY SSF53850 60 347 2.26E-65 T 31-10-2018 AF_0467 c1834bf1a3d83ac8e051a65b128fc179 355 Pfam PF16868 NMT1-like family 63 346 3.9E-65 T 31-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family AF_1433 d0b9f393f2d74ba2d1c1d32a1a4928d7 181 PIRSF PIRSF006380 1 181 3.0E-66 T 31-10-2018 IPR002802 Protein of unknown function DUF99 AF_1433 d0b9f393f2d74ba2d1c1d32a1a4928d7 181 Gene3D G3DSA:3.30.2170.10 1 181 6.8E-76 T 31-10-2018 AF_1433 d0b9f393f2d74ba2d1c1d32a1a4928d7 181 Hamap MF_00582 UPF0215 protein . 4 174 32.592 T 31-10-2018 IPR002802 Protein of unknown function DUF99 AF_1433 d0b9f393f2d74ba2d1c1d32a1a4928d7 181 ProDom PD016744 UPF0215 ST0304 TK2033 MA4269 PAE0952 SSO0256 NEQ431 MK0057 PTO0905 TV0037 52 176 9.0E-68 T 31-10-2018 IPR002802 Protein of unknown function DUF99 AF_1433 d0b9f393f2d74ba2d1c1d32a1a4928d7 181 Pfam PF01949 Protein of unknown function DUF99 3 172 5.8E-58 T 31-10-2018 IPR002802 Protein of unknown function DUF99 AF_0165 eca7547354f2f345c2dd65ba1862af77 77 Pfam PF01206 Sulfurtransferase TusA 12 76 7.7E-19 T 31-10-2018 IPR001455 TusA-like domain AF_0165 eca7547354f2f345c2dd65ba1862af77 77 SUPERFAMILY SSF64307 10 77 2.75E-17 T 31-10-2018 IPR036868 TusA-like domain superfamily AF_0165 eca7547354f2f345c2dd65ba1862af77 77 Gene3D G3DSA:3.30.110.40 12 77 5.4E-15 T 31-10-2018 IPR036868 TusA-like domain superfamily AF_1741 88544432e6220d4e5ca0f6855a05ef0f 178 Hamap MF_01208 Orotate phosphoribosyltransferase [pyrE]. 1 178 24.348 T 31-10-2018 IPR023031 Orotate phosphoribosyltransferase GO:0004588|GO:0006221 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AF_1741 88544432e6220d4e5ca0f6855a05ef0f 178 Gene3D G3DSA:3.40.50.2020 3 172 3.5E-50 T 31-10-2018 AF_1741 88544432e6220d4e5ca0f6855a05ef0f 178 Pfam PF00156 Phosphoribosyl transferase domain 52 155 1.8E-15 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AF_1741 88544432e6220d4e5ca0f6855a05ef0f 178 TIGRFAM TIGR00336 pyrE: orotate phosphoribosyltransferase 10 171 5.9E-62 T 31-10-2018 IPR004467 Orotate phosphoribosyl transferase domain GO:0004588 KEGG: 00240+2.4.2.10|KEGG: 00983+2.4.2.10|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791|Reactome: R-HSA-500753 AF_1741 88544432e6220d4e5ca0f6855a05ef0f 178 SUPERFAMILY SSF53271 6 166 2.36E-40 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like AF_1546 b8726bf73d193a0f18479421f072669d 283 SUPERFAMILY SSF82689 173 268 1.57E-33 T 31-10-2018 IPR011066 Mechanosensitive ion channel MscS, C-terminal GO:0016020 AF_1546 b8726bf73d193a0f18479421f072669d 283 SUPERFAMILY SSF50182 103 167 1.18E-17 T 31-10-2018 IPR010920 LSM domain superfamily AF_1546 b8726bf73d193a0f18479421f072669d 283 SUPERFAMILY SSF82861 19 101 1.7E-11 T 31-10-2018 IPR011014 Mechanosensitive ion channel MscS, transmembrane-2 GO:0016020 AF_1546 b8726bf73d193a0f18479421f072669d 283 Gene3D G3DSA:3.30.70.100 170 261 1.9E-29 T 31-10-2018 AF_1546 b8726bf73d193a0f18479421f072669d 283 Gene3D G3DSA:2.30.30.60 118 167 3.7E-15 T 31-10-2018 IPR023408 Mechanosensitive ion channel MscS domain superfamily AF_1546 b8726bf73d193a0f18479421f072669d 283 Pfam PF00924 Mechanosensitive ion channel 60 257 1.0E-62 T 31-10-2018 IPR006685 Mechanosensitive ion channel MscS GO:0016020|GO:0055085 AF_1546 b8726bf73d193a0f18479421f072669d 283 ProSitePatterns PS01246 Uncharacterized protein family UPF0003 signature. 132 166 - T 31-10-2018 IPR006686 Mechanosensitive ion channel MscS, conserved site GO:0016020 AF_0401 565aa905c35ac74762fdf7aac9007036 284 SUPERFAMILY SSF53613 8 267 2.03E-54 T 31-10-2018 IPR029056 Ribokinase-like AF_0401 565aa905c35ac74762fdf7aac9007036 284 Gene3D G3DSA:3.40.1190.20 6 282 1.6E-61 T 31-10-2018 IPR029056 Ribokinase-like AF_0401 565aa905c35ac74762fdf7aac9007036 284 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 224 237 - T 31-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AF_0401 565aa905c35ac74762fdf7aac9007036 284 Pfam PF00294 pfkB family carbohydrate kinase 29 268 2.3E-40 T 31-10-2018 IPR011611 Carbohydrate kinase PfkB AF_0401 565aa905c35ac74762fdf7aac9007036 284 ProSitePatterns PS00583 pfkB family of carbohydrate kinases signature 1. 36 60 - T 31-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AF_0520 f77ddb044af35476be13c708de577e03 280 Hamap MF_00370 Shikimate kinase [aroK]. 1 280 90.836 T 31-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AF_0520 f77ddb044af35476be13c708de577e03 280 ProSitePatterns PS00627 GHMP kinases putative ATP-binding domain. 73 84 - T 31-10-2018 IPR006203 GHMP kinase, ATP-binding, conserved site GO:0005524 AF_0520 f77ddb044af35476be13c708de577e03 280 Gene3D G3DSA:3.30.230.10 19 149 7.6E-17 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AF_0520 f77ddb044af35476be13c708de577e03 280 PIRSF PIRSF005758 1 270 4.0E-100 T 31-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AF_0520 f77ddb044af35476be13c708de577e03 280 Pfam PF00288 GHMP kinases N terminal domain 67 135 1.3E-10 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 AF_0520 f77ddb044af35476be13c708de577e03 280 SUPERFAMILY SSF54211 2 145 1.97E-18 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AF_0520 f77ddb044af35476be13c708de577e03 280 TIGRFAM TIGR01920 Shik_kin_archae: shikimate kinase 6 257 1.5E-98 T 31-10-2018 IPR010189 Shikimate kinase, archaea GO:0004765|GO:0005737|GO:0009073 KEGG: 00400+2.7.1.71|MetaCyc: PWY-6163 AF_1699 995465403fcff0ac7f132fa8ff1e3910 191 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 5 187 2.1E-76 T 31-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 AF_1699 995465403fcff0ac7f132fa8ff1e3910 191 SUPERFAMILY SSF53323 6 189 1.44E-52 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AF_1699 995465403fcff0ac7f132fa8ff1e3910 191 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 14 183 3.7E-42 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AF_1699 995465403fcff0ac7f132fa8ff1e3910 191 Gene3D G3DSA:3.40.920.10 3 188 4.2E-60 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AF_0865 76e4e3005588262dcb0d2b25a0c34768 266 Pfam PF00561 alpha/beta hydrolase fold 20 244 1.2E-27 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_0865 76e4e3005588262dcb0d2b25a0c34768 266 Gene3D G3DSA:3.40.50.1820 3 259 6.7E-61 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_0865 76e4e3005588262dcb0d2b25a0c34768 266 SUPERFAMILY SSF53474 6 256 1.18E-62 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_0865 76e4e3005588262dcb0d2b25a0c34768 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 105 118 1.3E-13 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_0865 76e4e3005588262dcb0d2b25a0c34768 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 91 104 1.3E-13 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_0865 76e4e3005588262dcb0d2b25a0c34768 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 202 216 1.3E-13 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_0865 76e4e3005588262dcb0d2b25a0c34768 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 45 60 1.3E-13 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_1877 64be3ef27fc1e164ee5cea0e7fb55ed2 189 Gene3D G3DSA:3.90.320.10 3 189 1.5E-15 T 31-10-2018 IPR011604 Exonuclease, phage-type/RecB, C-terminal AF_1877 64be3ef27fc1e164ee5cea0e7fb55ed2 189 Pfam PF01930 Domain of unknown function DUF83 12 189 2.6E-34 T 31-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 AF_1877 64be3ef27fc1e164ee5cea0e7fb55ed2 189 TIGRFAM TIGR00372 cas4: CRISPR-associated protein Cas4 10 189 1.1E-52 T 31-10-2018 IPR013343 CRISPR-associated protein Cas4 AF_1697 11f55c024f8e5fa9f733697a7cb1db3b 157 Pfam PF01022 Bacterial regulatory protein, arsR family 7 51 6.0E-17 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_1697 11f55c024f8e5fa9f733697a7cb1db3b 157 SMART SM00418 3 82 8.7E-22 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_1697 11f55c024f8e5fa9f733697a7cb1db3b 157 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 48 63 1.5E-8 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_1697 11f55c024f8e5fa9f733697a7cb1db3b 157 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 1 16 1.5E-8 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_1697 11f55c024f8e5fa9f733697a7cb1db3b 157 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 33 48 1.5E-8 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_1697 11f55c024f8e5fa9f733697a7cb1db3b 157 SUPERFAMILY SSF46785 7 71 1.67E-22 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1697 11f55c024f8e5fa9f733697a7cb1db3b 157 Gene3D G3DSA:1.10.10.10 4 86 9.8E-20 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1969 379ae80792b6144cb29b5c0e17c9b418 202 Gene3D G3DSA:3.30.700.20 5 191 2.2E-71 T 31-10-2018 IPR027485 AMMECR1, N-terminal AF_1969 379ae80792b6144cb29b5c0e17c9b418 202 Gene3D G3DSA:3.30.1490.150 107 179 2.2E-71 T 31-10-2018 AF_1969 379ae80792b6144cb29b5c0e17c9b418 202 Hamap MF_00645 Protein . 6 181 39.557 T 31-10-2018 IPR023472 Uncharacterised protein family MJ0810 AF_1969 379ae80792b6144cb29b5c0e17c9b418 202 TIGRFAM TIGR00296 TIGR00296: uncharacterized protein, PH0010 family 3 195 2.3E-92 T 31-10-2018 IPR023473 AMMECR1 AF_1969 379ae80792b6144cb29b5c0e17c9b418 202 TIGRFAM TIGR04335 AmmeMemoSam_A: AmmeMemoRadiSam system protein A 13 183 4.6E-57 T 31-10-2018 IPR027623 AmmeMemoRadiSam system protein A AF_1969 379ae80792b6144cb29b5c0e17c9b418 202 SUPERFAMILY SSF143447 3 196 1.7E-67 T 31-10-2018 IPR036071 AMMECR1 domain superfamily AF_1969 379ae80792b6144cb29b5c0e17c9b418 202 Pfam PF01871 AMMECR1 14 183 4.5E-52 T 31-10-2018 IPR002733 AMMECR1 domain AF_2267 be5b53c368a49461c1821c6dc2d58667 174 Gene3D G3DSA:3.40.109.10 1 174 1.0E-54 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AF_2267 be5b53c368a49461c1821c6dc2d58667 174 Pfam PF00881 Nitroreductase family 73 150 2.8E-11 T 31-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 AF_2267 be5b53c368a49461c1821c6dc2d58667 174 Pfam PF00881 Nitroreductase family 8 64 2.9E-18 T 31-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 AF_2267 be5b53c368a49461c1821c6dc2d58667 174 SUPERFAMILY SSF55469 1 172 1.96E-52 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AF_2267 be5b53c368a49461c1821c6dc2d58667 174 PIRSF PIRSF000232 1 174 8.3E-45 T 31-10-2018 IPR026021 Putative NAD(P)H nitroreductase YdjA-like AF_0104 7872dd5b317396948dda7af66e180304 138 Pfam PF03479 Domain of unknown function (DUF296) 12 118 2.5E-21 T 31-10-2018 IPR005175 PPC domain AF_0104 7872dd5b317396948dda7af66e180304 138 Gene3D G3DSA:3.30.1330.80 1 138 3.2E-58 T 31-10-2018 AF_0104 7872dd5b317396948dda7af66e180304 138 SUPERFAMILY SSF117856 1 138 9.16E-41 T 31-10-2018 AF_0104 7872dd5b317396948dda7af66e180304 138 PIRSF PIRSF016702 1 138 4.2E-50 T 31-10-2018 IPR025707 Predicted DNA-binding protein with PD1-like DNA-binding motif AF_0140 e554a8fce375a58d375b091384db1178 261 SUPERFAMILY SSF53335 24 220 1.03E-41 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_0140 e554a8fce375a58d375b091384db1178 261 Gene3D G3DSA:3.40.50.150 29 219 8.6E-42 T 31-10-2018 AF_0140 e554a8fce375a58d375b091384db1178 261 Pfam PF08241 Methyltransferase domain 65 157 4.5E-25 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AF_1093 00d11e19bcd2a3614d004947478ad786 85 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 6 84 3.6E-10 T 31-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family AF_1093 00d11e19bcd2a3614d004947478ad786 85 TIGRFAM TIGR02385 RelE_StbE: addiction module toxin, RelE/StbE family 6 84 1.2E-12 T 31-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family AF_1093 00d11e19bcd2a3614d004947478ad786 85 TIGRFAM TIGR00053 TIGR00053: addiction module toxin component, YafQ family 2 85 2.3E-27 T 31-10-2018 IPR004386 Toxin-antitoxin system, YafQ-like toxin AF_1093 00d11e19bcd2a3614d004947478ad786 85 Gene3D G3DSA:3.30.2310.20 2 85 2.8E-11 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AF_1093 00d11e19bcd2a3614d004947478ad786 85 SUPERFAMILY SSF143011 1 84 2.49E-15 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AF_0910 8422cc69a2a67d51504d77e91aace588 289 TIGRFAM TIGR00674 dapA: 4-hydroxy-tetrahydrodipicolinate synthase 4 284 9.2E-122 T 31-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AF_0910 8422cc69a2a67d51504d77e91aace588 289 Gene3D G3DSA:3.20.20.70 1 288 2.8E-113 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0910 8422cc69a2a67d51504d77e91aace588 289 SUPERFAMILY SSF51569 2 285 1.36E-102 T 31-10-2018 AF_0910 8422cc69a2a67d51504d77e91aace588 289 PIRSF PIRSF001365 1 288 7.4E-95 T 31-10-2018 IPR002220 DapA-like GO:0016829 AF_0910 8422cc69a2a67d51504d77e91aace588 289 SMART SM01130 1 286 3.1E-143 T 31-10-2018 IPR002220 DapA-like GO:0016829 AF_0910 8422cc69a2a67d51504d77e91aace588 289 ProSitePatterns PS00665 Dihydrodipicolinate synthase signature 1. 37 54 - T 31-10-2018 IPR020624 Schiff base-forming aldolase, conserved site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AF_0910 8422cc69a2a67d51504d77e91aace588 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 34 55 3.1E-34 T 31-10-2018 IPR002220 DapA-like GO:0016829 AF_0910 8422cc69a2a67d51504d77e91aace588 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 100 116 3.1E-34 T 31-10-2018 IPR002220 DapA-like GO:0016829 AF_0910 8422cc69a2a67d51504d77e91aace588 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 68 86 3.1E-34 T 31-10-2018 IPR002220 DapA-like GO:0016829 AF_0910 8422cc69a2a67d51504d77e91aace588 289 PRINTS PR00146 Dihydrodipicolinate synthase signature 125 142 3.1E-34 T 31-10-2018 IPR002220 DapA-like GO:0016829 AF_0910 8422cc69a2a67d51504d77e91aace588 289 ProSitePatterns PS00666 Dihydrodipicolinate synthase signature 2. 130 160 - T 31-10-2018 IPR020625 Schiff base-forming aldolase, active site GO:0016829 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|Reactome: R-HSA-389661 AF_0910 8422cc69a2a67d51504d77e91aace588 289 Hamap MF_00418 4-hydroxy-tetrahydrodipicolinate synthase [dapA]. 1 284 64.868 T 31-10-2018 IPR005263 4-hydroxy-tetrahydrodipicolinate synthase, DapA GO:0008840|GO:0009089 KEGG: 00261+4.3.3.7|KEGG: 00300+4.3.3.7|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097 AF_0910 8422cc69a2a67d51504d77e91aace588 289 Pfam PF00701 Dihydrodipicolinate synthetase family 2 284 1.2E-98 T 31-10-2018 IPR002220 DapA-like GO:0016829 AF_0329 84adae024a12d754108ff5b44f2f6c63 591 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 9 483 4.7E-16 T 31-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 AF_0329 84adae024a12d754108ff5b44f2f6c63 591 Gene3D G3DSA:3.40.50.12610 429 591 1.2E-54 T 31-10-2018 AF_2127 8ffc89a6f0f6f0cadfe3b574cef53e84 324 Gene3D G3DSA:3.40.190.10 115 296 1.2E-25 T 31-10-2018 AF_2127 8ffc89a6f0f6f0cadfe3b574cef53e84 324 Gene3D G3DSA:3.40.190.10 171 275 1.2E-25 T 31-10-2018 AF_2127 8ffc89a6f0f6f0cadfe3b574cef53e84 324 Pfam PF03466 LysR substrate binding domain 104 302 1.2E-33 T 31-10-2018 IPR005119 LysR, substrate-binding AF_2127 8ffc89a6f0f6f0cadfe3b574cef53e84 324 SUPERFAMILY SSF53850 104 308 1.09E-30 T 31-10-2018 AF_2127 8ffc89a6f0f6f0cadfe3b574cef53e84 324 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 12 69 1.8E-16 T 31-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AF_2127 8ffc89a6f0f6f0cadfe3b574cef53e84 324 Gene3D G3DSA:1.10.10.10 8 94 7.1E-21 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_2127 8ffc89a6f0f6f0cadfe3b574cef53e84 324 SUPERFAMILY SSF46785 6 93 7.78E-19 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_2191 1f794960c4bd493c902d1fde1ea8ec32 125 SUPERFAMILY SSF82093 38 123 2.49E-10 T 31-10-2018 IPR036127 CcmE-like superfamily GO:0005886|GO:0017003|GO:0017004 AF_2191 1f794960c4bd493c902d1fde1ea8ec32 125 Pfam PF03100 CcmE 23 123 2.2E-10 T 31-10-2018 IPR004329 CcmE/CycJ protein GO:0005886|GO:0017003|GO:0017004|GO:0020037 AF_2191 1f794960c4bd493c902d1fde1ea8ec32 125 Gene3D G3DSA:2.40.50.140 38 124 3.0E-8 T 31-10-2018 AF_1287 db15799b395c8d8dca22287ee6f637c9 586 SUPERFAMILY SSF56801 30 563 3.14E-128 T 31-10-2018 AF_1287 db15799b395c8d8dca22287ee6f637c9 586 Gene3D G3DSA:3.40.50.12780 16 458 5.8E-102 T 31-10-2018 AF_1287 db15799b395c8d8dca22287ee6f637c9 586 Gene3D G3DSA:3.30.300.30 460 578 8.0E-28 T 31-10-2018 AF_1287 db15799b395c8d8dca22287ee6f637c9 586 Pfam PF00501 AMP-binding enzyme 55 464 9.4E-69 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_1287 db15799b395c8d8dca22287ee6f637c9 586 Pfam PF13193 AMP-binding enzyme C-terminal domain 473 551 6.8E-23 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AF_1110 4fb734770402dc19a516d0b215ddcbb4 183 PIRSF PIRSF022079 1 183 5.4E-86 T 31-10-2018 IPR014518 Uncharacterised conserved protein UCP022079 AF_1110 4fb734770402dc19a516d0b215ddcbb4 183 Pfam PF09920 Uncharacterized protein conserved in archaea (DUF2150) 2 177 6.2E-52 T 31-10-2018 IPR014518 Uncharacterised conserved protein UCP022079 AF_2197 89b8529032230b49726092489b5b386f 395 Gene3D G3DSA:3.30.70.1450 110 190 2.9E-20 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AF_2197 89b8529032230b49726092489b5b386f 395 Gene3D G3DSA:3.30.70.1450 313 392 2.6E-18 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AF_2197 89b8529032230b49726092489b5b386f 395 SUPERFAMILY SSF116726 304 388 1.83E-18 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AF_2197 89b8529032230b49726092489b5b386f 395 Gene3D G3DSA:1.20.58.220 201 312 2.0E-13 T 31-10-2018 IPR038078 PhoU-like domain superfamily AF_2197 89b8529032230b49726092489b5b386f 395 Gene3D G3DSA:1.20.58.220 2 105 3.8E-14 T 31-10-2018 IPR038078 PhoU-like domain superfamily AF_2197 89b8529032230b49726092489b5b386f 395 Pfam PF02080 TrkA-C domain 320 387 2.3E-13 T 31-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AF_2197 89b8529032230b49726092489b5b386f 395 Pfam PF02080 TrkA-C domain 115 184 4.3E-16 T 31-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AF_2197 89b8529032230b49726092489b5b386f 395 SUPERFAMILY SSF109755 4 115 5.89E-12 T 31-10-2018 AF_2197 89b8529032230b49726092489b5b386f 395 Pfam PF01895 PhoU domain 10 91 6.1E-7 T 31-10-2018 IPR026022 PhoU domain AF_2197 89b8529032230b49726092489b5b386f 395 Pfam PF01895 PhoU domain 212 296 2.7E-12 T 31-10-2018 IPR026022 PhoU domain AF_2197 89b8529032230b49726092489b5b386f 395 SUPERFAMILY SSF116726 101 184 3.4E-19 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AF_2197 89b8529032230b49726092489b5b386f 395 SUPERFAMILY SSF109755 202 312 4.97E-13 T 31-10-2018 AF_1257 df7f9dd68223b36c97695d707fb622fb 320 SUPERFAMILY SSF53335 132 286 6.75E-29 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_1257 df7f9dd68223b36c97695d707fb622fb 320 SUPERFAMILY SSF143437 48 134 6.28E-7 T 31-10-2018 AF_1257 df7f9dd68223b36c97695d707fb622fb 320 TIGRFAM TIGR01177 TIGR01177: putative methyltransferase, TIGR01177 family 3 317 9.3E-123 T 31-10-2018 IPR005885 tRNA guanine(10)-N2-dimethyltransferase GO:0004809|GO:0030488 AF_1257 df7f9dd68223b36c97695d707fb622fb 320 Pfam PF02926 THUMP domain 17 134 4.9E-9 T 31-10-2018 IPR004114 THUMP domain GO:0003723 AF_1257 df7f9dd68223b36c97695d707fb622fb 320 Gene3D G3DSA:3.40.50.150 149 320 1.4E-34 T 31-10-2018 AF_1257 df7f9dd68223b36c97695d707fb622fb 320 Pfam PF01170 Putative RNA methylase family UPF0020 149 314 1.1E-45 T 31-10-2018 IPR000241 Putative RNA methylase domain AF_1257 df7f9dd68223b36c97695d707fb622fb 320 ProSitePatterns PS01261 Uncharacterized protein family UPF0020 signature. 182 193 - T 31-10-2018 IPR000241 Putative RNA methylase domain AF_1764 573b008547a29a0e6a1c7efdf461b6a3 157 ProSitePatterns PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. 78 113 - T 31-10-2018 IPR016192 APOBEC/CMP deaminase, zinc-binding GO:0008270|GO:0016787 AF_1764 573b008547a29a0e6a1c7efdf461b6a3 157 Pfam PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region 6 124 1.2E-31 T 31-10-2018 IPR002125 Cytidine and deoxycytidylate deaminase domain AF_1764 573b008547a29a0e6a1c7efdf461b6a3 157 PIRSF PIRSF006019 1 157 4.5E-58 T 31-10-2018 IPR016473 Deoxycytidylate deaminase GO:0004132|GO:0006220|GO:0008270 KEGG: 00240+3.5.4.12|MetaCyc: PWY-7210|Reactome: R-HSA-499943 AF_1764 573b008547a29a0e6a1c7efdf461b6a3 157 Gene3D G3DSA:3.40.140.10 1 157 5.4E-54 T 31-10-2018 AF_1764 573b008547a29a0e6a1c7efdf461b6a3 157 SUPERFAMILY SSF53927 7 151 1.24E-46 T 31-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 AF_1563 72d538b4b61dd0269899be300cce9abd 294 Pfam PF12697 Alpha/beta hydrolase family 41 272 1.4E-10 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_1563 72d538b4b61dd0269899be300cce9abd 294 SUPERFAMILY SSF53474 19 292 1.39E-40 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_1563 72d538b4b61dd0269899be300cce9abd 294 Gene3D G3DSA:1.10.10.800 142 223 2.2E-37 T 31-10-2018 AF_1563 72d538b4b61dd0269899be300cce9abd 294 Gene3D G3DSA:3.40.50.1820 36 274 2.2E-37 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_0142 0dd5d3daa0746ea194402fad56702900 153 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 81 134 - T 31-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AF_0142 0dd5d3daa0746ea194402fad56702900 153 SUPERFAMILY SSF49503 33 142 8.98E-17 T 31-10-2018 IPR008972 Cupredoxin AF_0142 0dd5d3daa0746ea194402fad56702900 153 Pfam PF00116 Cytochrome C oxidase subunit II, periplasmic domain 67 138 8.1E-5 T 31-10-2018 IPR002429 Cytochrome c oxidase subunit II-like C-terminal GO:0004129|GO:0005507|GO:0016020 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AF_0142 0dd5d3daa0746ea194402fad56702900 153 Gene3D G3DSA:2.60.40.420 24 141 8.2E-20 T 31-10-2018 IPR008972 Cupredoxin AF_0883 d5db57bc38522462208b1f8c34fdf777 483 Pfam PF14698 Argininosuccinate lyase C-terminal 355 425 8.9E-17 T 31-10-2018 IPR029419 Argininosuccinate lyase, C-terminal KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AF_0883 d5db57bc38522462208b1f8c34fdf777 483 PRINTS PR00149 Fumarate lyase superfamily signature 140 158 4.7E-22 T 31-10-2018 IPR000362 Fumarate lyase family AF_0883 d5db57bc38522462208b1f8c34fdf777 483 PRINTS PR00149 Fumarate lyase superfamily signature 224 251 4.7E-22 T 31-10-2018 IPR000362 Fumarate lyase family AF_0883 d5db57bc38522462208b1f8c34fdf777 483 PRINTS PR00149 Fumarate lyase superfamily signature 267 283 4.7E-22 T 31-10-2018 IPR000362 Fumarate lyase family AF_0883 d5db57bc38522462208b1f8c34fdf777 483 PRINTS PR00149 Fumarate lyase superfamily signature 96 114 4.7E-22 T 31-10-2018 IPR000362 Fumarate lyase family AF_0883 d5db57bc38522462208b1f8c34fdf777 483 PRINTS PR00145 Argininosuccinate lyase family signature 95 117 5.1E-46 T 31-10-2018 AF_0883 d5db57bc38522462208b1f8c34fdf777 483 PRINTS PR00145 Argininosuccinate lyase family signature 186 202 5.1E-46 T 31-10-2018 AF_0883 d5db57bc38522462208b1f8c34fdf777 483 PRINTS PR00145 Argininosuccinate lyase family signature 267 283 5.1E-46 T 31-10-2018 AF_0883 d5db57bc38522462208b1f8c34fdf777 483 PRINTS PR00145 Argininosuccinate lyase family signature 302 321 5.1E-46 T 31-10-2018 AF_0883 d5db57bc38522462208b1f8c34fdf777 483 PRINTS PR00145 Argininosuccinate lyase family signature 224 248 5.1E-46 T 31-10-2018 AF_0883 d5db57bc38522462208b1f8c34fdf777 483 PRINTS PR00145 Argininosuccinate lyase family signature 135 155 5.1E-46 T 31-10-2018 AF_0883 d5db57bc38522462208b1f8c34fdf777 483 Gene3D G3DSA:1.10.275.10 27 222 4.5E-142 T 31-10-2018 IPR024083 Fumarase/histidase, N-terminal AF_0883 d5db57bc38522462208b1f8c34fdf777 483 Hamap MF_00006 Argininosuccinate lyase [argH]. 1 447 38.632 T 31-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AF_0883 d5db57bc38522462208b1f8c34fdf777 483 TIGRFAM TIGR00838 argH: argininosuccinate lyase 2 449 6.7E-185 T 31-10-2018 IPR009049 Argininosuccinate lyase GO:0004056|GO:0042450 KEGG: 00220+4.3.2.1|KEGG: 00250+4.3.2.1|MetaCyc: PWY-4983|MetaCyc: PWY-4984|MetaCyc: PWY-5|MetaCyc: PWY-5154|MetaCyc: PWY-7400|Reactome: R-HSA-70635 AF_0883 d5db57bc38522462208b1f8c34fdf777 483 Gene3D G3DSA:1.10.40.30 352 426 4.5E-142 T 31-10-2018 AF_0883 d5db57bc38522462208b1f8c34fdf777 483 Gene3D G3DSA:1.20.200.10 113 442 4.5E-142 T 31-10-2018 AF_0883 d5db57bc38522462208b1f8c34fdf777 483 Pfam PF00206 Lyase 32 292 3.4E-51 T 31-10-2018 IPR022761 Fumarate lyase, N-terminal AF_0883 d5db57bc38522462208b1f8c34fdf777 483 SUPERFAMILY SSF48557 6 451 2.04E-111 T 31-10-2018 IPR008948 L-Aspartase-like GO:0003824 AF_0938 154c2ed84bc6aede84382aaabf4b22b8 106 SMART SM01403 9 103 3.4E-41 T 31-10-2018 IPR027486 Ribosomal protein S10 domain AF_0938 154c2ed84bc6aede84382aaabf4b22b8 106 Pfam PF00338 Ribosomal protein S10p/S20e 9 102 6.5E-27 T 31-10-2018 IPR027486 Ribosomal protein S10 domain AF_0938 154c2ed84bc6aede84382aaabf4b22b8 106 ProSitePatterns PS00361 Ribosomal protein S10 signature. 31 46 - T 31-10-2018 IPR018268 Ribosomal protein S10, conserved site GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0938 154c2ed84bc6aede84382aaabf4b22b8 106 SUPERFAMILY SSF54999 7 103 1.57E-29 T 31-10-2018 IPR036838 Ribosomal protein S10 domain superfamily AF_0938 154c2ed84bc6aede84382aaabf4b22b8 106 PRINTS PR00971 Ribosomal protein S10 family signature 64 78 7.3E-16 T 31-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0938 154c2ed84bc6aede84382aaabf4b22b8 106 PRINTS PR00971 Ribosomal protein S10 family signature 42 57 7.3E-16 T 31-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0938 154c2ed84bc6aede84382aaabf4b22b8 106 PRINTS PR00971 Ribosomal protein S10 family signature 7 20 7.3E-16 T 31-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0938 154c2ed84bc6aede84382aaabf4b22b8 106 TIGRFAM TIGR01046 uS10_euk_arch: ribosomal protein uS10 7 103 9.4E-52 T 31-10-2018 IPR005729 Ribosomal protein S10, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0938 154c2ed84bc6aede84382aaabf4b22b8 106 Gene3D G3DSA:3.30.70.600 3 104 1.6E-33 T 31-10-2018 IPR036838 Ribosomal protein S10 domain superfamily AF_0938 154c2ed84bc6aede84382aaabf4b22b8 106 Hamap MF_00508 30S ribosomal protein S10 [rpsJ]. 5 104 24.939 T 31-10-2018 IPR001848 Ribosomal protein S10 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0930 6d04ee897fb83ba1dda793d9c7cb7192 414 Pfam PF03453 MoeA N-terminal region (domain I and II) 13 175 3.0E-46 T 31-10-2018 IPR005110 MoeA, N-terminal and linker domain GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AF_0930 6d04ee897fb83ba1dda793d9c7cb7192 414 SUPERFAMILY SSF63867 337 406 6.41E-17 T 31-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AF_0930 6d04ee897fb83ba1dda793d9c7cb7192 414 SUPERFAMILY SSF53218 185 328 7.46E-40 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily AF_0930 6d04ee897fb83ba1dda793d9c7cb7192 414 Pfam PF03454 MoeA C-terminal region (domain IV) 340 406 1.1E-17 T 31-10-2018 IPR005111 MoeA, C-terminal, domain IV GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AF_0930 6d04ee897fb83ba1dda793d9c7cb7192 414 SUPERFAMILY SSF63882 12 184 1.57E-56 T 31-10-2018 IPR036135 MoeA, N-terminal and linker domain superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AF_0930 6d04ee897fb83ba1dda793d9c7cb7192 414 SMART SM00852 188 324 6.7E-42 T 31-10-2018 IPR001453 MoaB/Mog domain AF_0930 6d04ee897fb83ba1dda793d9c7cb7192 414 Gene3D G3DSA:2.170.190.11 53 149 1.7E-107 T 31-10-2018 AF_0930 6d04ee897fb83ba1dda793d9c7cb7192 414 Gene3D G3DSA:3.40.980.10 183 323 1.7E-107 T 31-10-2018 IPR036425 MoaB/Mog-like domain superfamily AF_0930 6d04ee897fb83ba1dda793d9c7cb7192 414 Pfam PF00994 Probable molybdopterin binding domain 188 322 2.1E-28 T 31-10-2018 IPR001453 MoaB/Mog domain AF_0930 6d04ee897fb83ba1dda793d9c7cb7192 414 Gene3D G3DSA:3.90.105.10 31 182 1.7E-107 T 31-10-2018 AF_0930 6d04ee897fb83ba1dda793d9c7cb7192 414 TIGRFAM TIGR00177 molyb_syn: molybdenum cofactor synthesis domain 184 320 2.8E-35 T 31-10-2018 IPR001453 MoaB/Mog domain AF_0930 6d04ee897fb83ba1dda793d9c7cb7192 414 Gene3D G3DSA:2.40.340.10 334 405 4.8E-21 T 31-10-2018 IPR036688 MoeA, C-terminal, domain IV superfamily GO:0032324 KEGG: 00790+2.10.1.1|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AF_1112 5aef84061c4a22343de26f8ce7e2f446 323 Gene3D G3DSA:3.30.420.40 3 299 8.8E-103 T 31-10-2018 AF_1112 5aef84061c4a22343de26f8ce7e2f446 323 Hamap MF_01446 tRNA N6-adenosine threonylcarbamoyltransferase [kae1]. 1 323 37.539 T 31-10-2018 IPR034680 tRNA N6-adenosine threonylcarbamoyltransferase Kae1/OSGEP GO:0000408|GO:0002949 Reactome: R-HSA-6782315 AF_1112 5aef84061c4a22343de26f8ce7e2f446 323 Gene3D G3DSA:3.30.420.40 121 276 8.8E-103 T 31-10-2018 AF_1112 5aef84061c4a22343de26f8ce7e2f446 323 TIGRFAM TIGR03722 arch_KAE1: universal archaeal protein Kae1 4 322 1.4E-156 T 31-10-2018 IPR022449 tRNA N6-adenosine threonylcarbamoyltransferase Kae1, archaea GO:0000408|GO:0002949 AF_1112 5aef84061c4a22343de26f8ce7e2f446 323 SUPERFAMILY SSF53067 1 290 1.28E-34 T 31-10-2018 AF_1112 5aef84061c4a22343de26f8ce7e2f446 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 91 110 3.7E-40 T 31-10-2018 IPR017861 Kae1/TsaD family AF_1112 5aef84061c4a22343de26f8ce7e2f446 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 145 166 3.7E-40 T 31-10-2018 IPR017861 Kae1/TsaD family AF_1112 5aef84061c4a22343de26f8ce7e2f446 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 70 90 3.7E-40 T 31-10-2018 IPR017861 Kae1/TsaD family AF_1112 5aef84061c4a22343de26f8ce7e2f446 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 123 135 3.7E-40 T 31-10-2018 IPR017861 Kae1/TsaD family AF_1112 5aef84061c4a22343de26f8ce7e2f446 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 246 255 3.7E-40 T 31-10-2018 IPR017861 Kae1/TsaD family AF_1112 5aef84061c4a22343de26f8ce7e2f446 323 PRINTS PR00789 O-sialoglycoprotein endopeptidase (M22) metallo-protease family signature 4 17 3.7E-40 T 31-10-2018 IPR017861 Kae1/TsaD family AF_1112 5aef84061c4a22343de26f8ce7e2f446 323 TIGRFAM TIGR00329 gcp_kae1: metallohydrolase, glycoprotease/Kae1 family 4 289 1.3E-109 T 31-10-2018 IPR017861 Kae1/TsaD family AF_1112 5aef84061c4a22343de26f8ce7e2f446 323 Pfam PF00814 Glycoprotease family 28 290 7.8E-91 T 31-10-2018 IPR000905 Gcp-like domain AF_0534 9094b318ce6edca51458a7687e77373c 319 Gene3D G3DSA:1.10.10.10 254 318 2.9E-7 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0534 9094b318ce6edca51458a7687e77373c 319 SMART SM00849 23 225 4.9E-40 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_0534 9094b318ce6edca51458a7687e77373c 319 SUPERFAMILY SSF56281 3 315 1.23E-61 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_0534 9094b318ce6edca51458a7687e77373c 319 Gene3D G3DSA:3.60.15.10 2 253 1.6E-62 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_0534 9094b318ce6edca51458a7687e77373c 319 Pfam PF00753 Metallo-beta-lactamase superfamily 22 225 1.5E-24 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_1506 20950654e8b3fe4ea2a5d0487e74ed86 343 Gene3D G3DSA:3.30.360.10 149 320 3.7E-142 T 31-10-2018 AF_1506 20950654e8b3fe4ea2a5d0487e74ed86 343 Gene3D G3DSA:3.40.50.720 5 338 3.7E-142 T 31-10-2018 AF_1506 20950654e8b3fe4ea2a5d0487e74ed86 343 SUPERFAMILY SSF51735 3 174 3.33E-47 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1506 20950654e8b3fe4ea2a5d0487e74ed86 343 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 157 323 1.9E-45 T 31-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AF_1506 20950654e8b3fe4ea2a5d0487e74ed86 343 PIRSF PIRSF000148 2 343 7.7E-110 T 31-10-2018 AF_1506 20950654e8b3fe4ea2a5d0487e74ed86 343 SMART SM00859 4 129 4.5E-41 T 31-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AF_1506 20950654e8b3fe4ea2a5d0487e74ed86 343 ProSitePatterns PS01103 Aspartate-semialdehyde dehydrogenase signature. 227 241 - T 31-10-2018 IPR000319 Aspartate-semialdehyde dehydrogenase, conserved site GO:0004073|GO:0006520|GO:0050661|GO:0055114 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AF_1506 20950654e8b3fe4ea2a5d0487e74ed86 343 Hamap MF_02121 Aspartate-semialdehyde dehydrogenase [asd]. 2 338 35.305 T 31-10-2018 IPR012080 Aspartate-semialdehyde dehydrogenase GO:0004073|GO:0009086|GO:0009088|GO:0009089|GO:0009097|GO:0050661 KEGG: 00260+1.2.1.11|KEGG: 00261+1.2.1.11|KEGG: 00270+1.2.1.11|KEGG: 00300+1.2.1.11|MetaCyc: PWY-2941|MetaCyc: PWY-2942|MetaCyc: PWY-5097|MetaCyc: PWY-6160|MetaCyc: PWY-6559|MetaCyc: PWY-6562|MetaCyc: PWY-7153|MetaCyc: PWY-7977 AF_1506 20950654e8b3fe4ea2a5d0487e74ed86 343 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 5 126 7.1E-36 T 31-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AF_1506 20950654e8b3fe4ea2a5d0487e74ed86 343 TIGRFAM TIGR00978 asd_EA: aspartate-semialdehyde dehydrogenase 5 338 2.7E-146 T 31-10-2018 IPR005676 Aspartate-semialdehyde dehydrogenase, peptidoglycan lacking GO:0050661|GO:0055114 AF_1506 20950654e8b3fe4ea2a5d0487e74ed86 343 SUPERFAMILY SSF55347 146 325 3.82E-46 T 31-10-2018 AF_1585 90420be5897991c58a65f2c9cda0c5ed 112 SUPERFAMILY SSF81593 3 111 2.08E-22 T 31-10-2018 AF_1585 90420be5897991c58a65f2c9cda0c5ed 112 SMART SM00748 5 108 1.1E-31 T 31-10-2018 IPR007842 HEPN domain AF_1585 90420be5897991c58a65f2c9cda0c5ed 112 Pfam PF05168 HEPN domain 1 111 4.2E-26 T 31-10-2018 IPR007842 HEPN domain AF_1585 90420be5897991c58a65f2c9cda0c5ed 112 Gene3D G3DSA:1.20.120.330 1 112 8.9E-20 T 31-10-2018 AF_1746 42c129e0c0867aa9edc15115390b0f86 468 Gene3D G3DSA:1.10.3430.10 17 459 5.4E-146 T 31-10-2018 IPR029020 Ammonium/urea transporter AF_1746 42c129e0c0867aa9edc15115390b0f86 468 Pfam PF00909 Ammonium Transporter Family 40 448 4.4E-140 T 31-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 AF_1746 42c129e0c0867aa9edc15115390b0f86 468 TIGRFAM TIGR00836 amt: ammonium transporter 38 448 3.7E-147 T 31-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 AF_1746 42c129e0c0867aa9edc15115390b0f86 468 SUPERFAMILY SSF111352 37 429 7.19E-115 T 31-10-2018 AF_1746 42c129e0c0867aa9edc15115390b0f86 468 PRINTS PR00342 Rhesus blood group protein signature 237 255 5.9E-10 T 31-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 AF_1746 42c129e0c0867aa9edc15115390b0f86 468 PRINTS PR00342 Rhesus blood group protein signature 142 158 5.9E-10 T 31-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 AF_1746 42c129e0c0867aa9edc15115390b0f86 468 PRINTS PR00342 Rhesus blood group protein signature 324 342 5.9E-10 T 31-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 AF_1746 42c129e0c0867aa9edc15115390b0f86 468 PRINTS PR00342 Rhesus blood group protein signature 200 215 5.9E-10 T 31-10-2018 IPR002229 Blood group Rhesus C/E/D polypeptide GO:0016020 AF_1746 42c129e0c0867aa9edc15115390b0f86 468 ProSitePatterns PS01219 Ammonium transporters signature. 193 218 - T 31-10-2018 IPR018047 Ammonium transporter, conserved site GO:0008519|GO:0016020|GO:0072488 AF_0632 7050872c9d7cfdbca08ebd61db82a689 77 ProDom PD002830 NIFU NIFU NITROGEN-FIXING C-TERMINAL FIXATION NITROGEN NIFU-LIKE DOMAIN CLUSTER HESB/YADR/YFHF:NITROGEN-FIXING 14 66 8.0E-25 T 31-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 AF_0632 7050872c9d7cfdbca08ebd61db82a689 77 SUPERFAMILY SSF117916 2 77 1.96E-23 T 31-10-2018 IPR034904 Fe-S cluster assembly domain superfamily AF_0632 7050872c9d7cfdbca08ebd61db82a689 77 Pfam PF01106 NifU-like domain 7 75 2.1E-27 T 31-10-2018 IPR001075 NIF system FeS cluster assembly, NifU, C-terminal GO:0005506|GO:0016226|GO:0051536 AF_0632 7050872c9d7cfdbca08ebd61db82a689 77 Gene3D G3DSA:3.30.300.130 1 77 3.0E-27 T 31-10-2018 IPR034904 Fe-S cluster assembly domain superfamily AF_1376 4c3b336d94fcf022a74b02603380f804 160 Pfam PF13534 4Fe-4S dicluster domain 26 86 4.0E-9 T 31-10-2018 AF_1376 4c3b336d94fcf022a74b02603380f804 160 Gene3D G3DSA:3.30.70.3270 8 146 4.0E-9 T 31-10-2018 AF_1376 4c3b336d94fcf022a74b02603380f804 160 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 27 38 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1376 4c3b336d94fcf022a74b02603380f804 160 SUPERFAMILY SSF46548 23 101 7.32E-17 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_1666 acabc9abd768cce1a8dd0f195d368e8c 222 PIRSF PIRSF039123 1 222 7.5E-82 T 31-10-2018 IPR030662 Diphthine--ammonia ligase/Uncharacterised protein MJ0570 MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 AF_1666 acabc9abd768cce1a8dd0f195d368e8c 222 Gene3D G3DSA:3.40.50.620 1 121 6.8E-37 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_1666 acabc9abd768cce1a8dd0f195d368e8c 222 SUPERFAMILY SSF52402 1 217 4.19E-67 T 31-10-2018 AF_1666 acabc9abd768cce1a8dd0f195d368e8c 222 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 1 222 4.1E-102 T 31-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 AF_1666 acabc9abd768cce1a8dd0f195d368e8c 222 Pfam PF01902 Diphthamide synthase 1 217 5.6E-107 T 31-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 AF_1666 acabc9abd768cce1a8dd0f195d368e8c 222 TIGRFAM TIGR03679 arCOG00187: arCOG00187 universal archaeal metal-binding-domain/4Fe-4S-binding-domain containing ABC transporter, ATP-binding protein 4 215 5.2E-84 T 31-10-2018 IPR022427 Uncharacterised protein MJ0570, ATP-binding AF_1666 acabc9abd768cce1a8dd0f195d368e8c 222 TIGRFAM TIGR00289 TIGR00289: TIGR00289 family protein 1 222 2.1E-119 T 31-10-2018 IPR005237 Uncharacterised protein MJ0570 AF_1666 acabc9abd768cce1a8dd0f195d368e8c 222 Gene3D G3DSA:3.90.1490.10 122 220 2.5E-31 T 31-10-2018 AF_2277 d7783b4aedae8f53ec8cdf0364d47aa2 199 SMART SM00986 28 182 5.4E-38 T 31-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AF_2277 d7783b4aedae8f53ec8cdf0364d47aa2 199 SMART SM00987 28 182 5.4E-38 T 31-10-2018 AF_2277 d7783b4aedae8f53ec8cdf0364d47aa2 199 SUPERFAMILY SSF52141 2 186 5.23E-60 T 31-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AF_2277 d7783b4aedae8f53ec8cdf0364d47aa2 199 TIGRFAM TIGR00758 UDG_fam4: uracil-DNA glycosylase, family 4 14 189 6.3E-84 T 31-10-2018 IPR005273 Uracil-DNA glycosylase family 4 AF_2277 d7783b4aedae8f53ec8cdf0364d47aa2 199 Gene3D G3DSA:3.40.470.10 1 190 5.6E-70 T 31-10-2018 IPR036895 Uracil-DNA glycosylase-like domain superfamily Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AF_2277 d7783b4aedae8f53ec8cdf0364d47aa2 199 Pfam PF03167 Uracil DNA glycosylase superfamily 28 177 3.6E-44 T 31-10-2018 IPR005122 Uracil-DNA glycosylase-like Reactome: R-HSA-110328|Reactome: R-HSA-110329|Reactome: R-HSA-110357 AF_1453 1549db4fcd913c177e42ab4ede8da229 658 SUPERFAMILY SSF50249 557 657 6.86E-34 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_1453 1549db4fcd913c177e42ab4ede8da229 658 TIGRFAM TIGR00399 metG_C_term: methionine--tRNA ligase, beta subunit 528 658 1.1E-51 T 31-10-2018 IPR004495 Methionyl-tRNA synthetase, beta subunit, C-terminal GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AF_1453 1549db4fcd913c177e42ab4ede8da229 658 Pfam PF08264 Anticodon-binding domain of tRNA 404 538 7.9E-10 T 31-10-2018 IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding GO:0004812|GO:0006418 AF_1453 1549db4fcd913c177e42ab4ede8da229 658 Hamap MF_00098 Methionine--tRNA ligase [metG]. 1 536 39.389 T 31-10-2018 IPR023458 Methionine-tRNA ligase, type 1 GO:0004825 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AF_1453 1549db4fcd913c177e42ab4ede8da229 658 PRINTS PR01041 Methionyl-tRNA synthetase signature 36 50 5.9E-26 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AF_1453 1549db4fcd913c177e42ab4ede8da229 658 PRINTS PR01041 Methionyl-tRNA synthetase signature 375 386 5.9E-26 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AF_1453 1549db4fcd913c177e42ab4ede8da229 658 PRINTS PR01041 Methionyl-tRNA synthetase signature 281 296 5.9E-26 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AF_1453 1549db4fcd913c177e42ab4ede8da229 658 PRINTS PR01041 Methionyl-tRNA synthetase signature 4 17 5.9E-26 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AF_1453 1549db4fcd913c177e42ab4ede8da229 658 PRINTS PR01041 Methionyl-tRNA synthetase signature 243 254 5.9E-26 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AF_1453 1549db4fcd913c177e42ab4ede8da229 658 PRINTS PR01041 Methionyl-tRNA synthetase signature 84 95 5.9E-26 T 31-10-2018 IPR033911 Methioninyl-tRNA synthetase core domain GO:0004825|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AF_1453 1549db4fcd913c177e42ab4ede8da229 658 Gene3D G3DSA:3.40.50.620 3 370 1.7E-144 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_1453 1549db4fcd913c177e42ab4ede8da229 658 TIGRFAM TIGR00398 metG: methionine--tRNA ligase 3 526 5.1E-202 T 31-10-2018 IPR014758 Methionyl-tRNA synthetase GO:0000166|GO:0004825|GO:0005524|GO:0005737|GO:0006431 KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10 AF_1453 1549db4fcd913c177e42ab4ede8da229 658 Pfam PF09334 tRNA synthetases class I (M) 3 388 2.1E-152 T 31-10-2018 IPR015413 Methionyl/Leucyl tRNA synthetase GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_1453 1549db4fcd913c177e42ab4ede8da229 658 SUPERFAMILY SSF52374 3 374 2.56E-107 T 31-10-2018 AF_1453 1549db4fcd913c177e42ab4ede8da229 658 Gene3D G3DSA:2.40.50.140 547 658 1.9E-40 T 31-10-2018 AF_1453 1549db4fcd913c177e42ab4ede8da229 658 Gene3D G3DSA:1.10.730.10 371 538 1.1E-31 T 31-10-2018 AF_1453 1549db4fcd913c177e42ab4ede8da229 658 Gene3D G3DSA:2.20.28.20 136 170 1.7E-144 T 31-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AF_1453 1549db4fcd913c177e42ab4ede8da229 658 SUPERFAMILY SSF57770 136 170 1.31E-5 T 31-10-2018 IPR029038 Methionyl-tRNA synthetase, Zn-domain KEGG: 00450+6.1.1.10|KEGG: 00970+6.1.1.10|Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AF_1453 1549db4fcd913c177e42ab4ede8da229 658 SUPERFAMILY SSF47323 379 571 8.22E-34 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_1453 1549db4fcd913c177e42ab4ede8da229 658 Pfam PF01588 Putative tRNA binding domain 564 656 4.1E-31 T 31-10-2018 IPR002547 tRNA-binding domain GO:0000049 Reactome: R-HSA-379716 AF_0996 2448a4530faa13905e428359088c1607 569 SUPERFAMILY SSF52540 169 498 9.55E-61 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0996 2448a4530faa13905e428359088c1607 569 Pfam PF00437 Type II/IV secretion system protein 193 436 8.6E-51 T 31-10-2018 IPR001482 Type II/IV secretion system protein AF_0996 2448a4530faa13905e428359088c1607 569 Gene3D G3DSA:3.30.450.380 62 286 3.5E-70 T 31-10-2018 AF_0996 2448a4530faa13905e428359088c1607 569 Gene3D G3DSA:3.40.50.300 288 569 3.5E-106 T 31-10-2018 AF_1197 a21ec206629b82776be176a45dd0dcb4 424 Pfam PF02803 Thiolase, C-terminal domain 302 423 4.9E-49 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 AF_1197 a21ec206629b82776be176a45dd0dcb4 424 ProSitePatterns PS00099 Thiolases active site. 405 418 - T 31-10-2018 IPR020610 Thiolase, active site GO:0016747 AF_1197 a21ec206629b82776be176a45dd0dcb4 424 SUPERFAMILY SSF53901 302 423 2.54E-45 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_1197 a21ec206629b82776be176a45dd0dcb4 424 SUPERFAMILY SSF53901 76 301 4.26E-79 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_1197 a21ec206629b82776be176a45dd0dcb4 424 ProSitePatterns PS00098 Thiolases acyl-enzyme intermediate signature. 113 131 - T 31-10-2018 IPR020615 Thiolase, acyl-enzyme intermediate active site GO:0016747 AF_1197 a21ec206629b82776be176a45dd0dcb4 424 PIRSF PIRSF000429 72 424 7.0E-130 T 31-10-2018 IPR002155 Thiolase GO:0016747 AF_1197 a21ec206629b82776be176a45dd0dcb4 424 PIRSF PIRSF000429 1 50 1.9E-7 T 31-10-2018 IPR002155 Thiolase GO:0016747 AF_1197 a21ec206629b82776be176a45dd0dcb4 424 Pfam PF00108 Thiolase, N-terminal domain 3 44 2.1E-8 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AF_1197 a21ec206629b82776be176a45dd0dcb4 424 Pfam PF00108 Thiolase, N-terminal domain 76 293 2.9E-88 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AF_1197 a21ec206629b82776be176a45dd0dcb4 424 SUPERFAMILY SSF53901 2 44 3.84E-7 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_1197 a21ec206629b82776be176a45dd0dcb4 424 TIGRFAM TIGR01930 AcCoA-C-Actrans: acetyl-CoA C-acyltransferase 75 422 7.7E-141 T 31-10-2018 IPR002155 Thiolase GO:0016747 AF_0681 6612d2284d2b35b28dde9583c082974e 563 SUPERFAMILY SSF46977 430 563 9.29E-53 T 31-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_0681 6612d2284d2b35b28dde9583c082974e 563 Gene3D G3DSA:3.50.50.60 4 395 1.0E-157 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0681 6612d2284d2b35b28dde9583c082974e 563 Pfam PF00890 FAD binding domain 4 382 2.0E-116 T 31-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_0681 6612d2284d2b35b28dde9583c082974e 563 Pfam PF02910 Fumarate reductase flavoprotein C-term 438 563 1.3E-44 T 31-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_0681 6612d2284d2b35b28dde9583c082974e 563 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 346 368 8.9E-9 T 31-10-2018 AF_0681 6612d2284d2b35b28dde9583c082974e 563 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 8.9E-9 T 31-10-2018 AF_0681 6612d2284d2b35b28dde9583c082974e 563 Gene3D G3DSA:4.10.80.40 526 559 2.8E-10 T 31-10-2018 AF_0681 6612d2284d2b35b28dde9583c082974e 563 TIGRFAM TIGR01812 sdhA_frdA_Gneg: succinate dehydrogenase or fumarate reductase, flavoprotein subunit 4 563 2.6E-265 T 31-10-2018 IPR014006 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit GO:0016627|GO:0022900|GO:0050660|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_0681 6612d2284d2b35b28dde9583c082974e 563 SUPERFAMILY SSF56425 224 344 2.24E-44 T 31-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_0681 6612d2284d2b35b28dde9583c082974e 563 PIRSF PIRSF000171 1 558 4.8E-52 T 31-10-2018 AF_0681 6612d2284d2b35b28dde9583c082974e 563 Gene3D G3DSA:1.20.58.100 408 525 1.8E-39 T 31-10-2018 AF_0681 6612d2284d2b35b28dde9583c082974e 563 SUPERFAMILY SSF51905 2 405 2.97E-79 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0681 6612d2284d2b35b28dde9583c082974e 563 Gene3D G3DSA:3.90.700.10 234 349 1.0E-157 T 31-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_0617 5a803e376fd6c0a8f3d6be35607c5f51 358 Gene3D G3DSA:3.40.50.2000 189 343 4.5E-31 T 31-10-2018 AF_0617 5a803e376fd6c0a8f3d6be35607c5f51 358 Gene3D G3DSA:3.40.50.2000 1 188 2.1E-37 T 31-10-2018 AF_0617 5a803e376fd6c0a8f3d6be35607c5f51 358 SUPERFAMILY SSF53756 3 355 1.75E-72 T 31-10-2018 AF_0617 5a803e376fd6c0a8f3d6be35607c5f51 358 Pfam PF00534 Glycosyl transferases group 1 184 330 6.6E-29 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 AF_0617 5a803e376fd6c0a8f3d6be35607c5f51 358 Pfam PF13439 Glycosyltransferase Family 4 14 179 1.4E-33 T 31-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AF_0899 6ff2e6027ed8498edda724e72aea3085 274 ProDom PD038341 HYDROLASE COFACTOR MOLYBDENUM BIOSYNTHESIS METAL-DEPENDENT DEOXYRIBONUCLEASE PREDICTED TATD-RELATED TVG0313409 A 101 273 7.0E-97 T 31-10-2018 AF_0899 6ff2e6027ed8498edda724e72aea3085 274 Pfam PF01026 TatD related DNase 5 268 7.5E-29 T 31-10-2018 IPR001130 TatD family GO:0016788 AF_0899 6ff2e6027ed8498edda724e72aea3085 274 PIRSF PIRSF004961 1 274 3.2E-114 T 31-10-2018 IPR011589 Protein of unknown function UCP004961 AF_0899 6ff2e6027ed8498edda724e72aea3085 274 SUPERFAMILY SSF51556 2 270 3.12E-24 T 31-10-2018 IPR032466 Metal-dependent hydrolase AF_0899 6ff2e6027ed8498edda724e72aea3085 274 Gene3D G3DSA:3.20.20.140 3 273 1.6E-20 T 31-10-2018 AF_1691 de8093e216a636506006b2d32a9e8f40 267 SUPERFAMILY SSF103481 35 132 1.09E-11 T 31-10-2018 AF_1691 de8093e216a636506006b2d32a9e8f40 267 Pfam PF00892 EamA-like transporter family 3 128 6.7E-8 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AF_1691 de8093e216a636506006b2d32a9e8f40 267 Pfam PF00892 EamA-like transporter family 137 265 1.2E-13 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AF_1691 de8093e216a636506006b2d32a9e8f40 267 SUPERFAMILY SSF103481 172 264 5.75E-11 T 31-10-2018 AF_0253 b345ce1f9af7c9770640c65f3c50eac5 303 Gene3D G3DSA:3.30.300.10 189 303 4.4E-43 T 31-10-2018 AF_0253 b345ce1f9af7c9770640c65f3c50eac5 303 SUPERFAMILY SSF54810 188 303 3.4E-40 T 31-10-2018 AF_0253 b345ce1f9af7c9770640c65f3c50eac5 303 Pfam PF02540 NAD synthase 10 185 1.7E-10 T 31-10-2018 IPR022310 NAD/GMP synthase AF_0253 b345ce1f9af7c9770640c65f3c50eac5 303 Gene3D G3DSA:3.40.50.620 1 188 3.0E-72 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_0253 b345ce1f9af7c9770640c65f3c50eac5 303 Pfam PF00958 GMP synthase C terminal domain 219 302 2.1E-30 T 31-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AF_0253 b345ce1f9af7c9770640c65f3c50eac5 303 TIGRFAM TIGR00884 guaA_Cterm: GMP synthase (glutamine-hydrolyzing), C-terminal domain 5 303 7.4E-141 T 31-10-2018 IPR001674 GMP synthase, C-terminal GO:0003922|GO:0005524|GO:0006164|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AF_0253 b345ce1f9af7c9770640c65f3c50eac5 303 Hamap MF_00345 GMP synthase [glutamine-hydrolyzing] subunit B [guaAB]. 1 303 48.207 T 31-10-2018 IPR026598 GMP synthase subunit B KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 AF_0253 b345ce1f9af7c9770640c65f3c50eac5 303 SUPERFAMILY SSF52402 2 218 1.1E-52 T 31-10-2018 AF_0834 62875a8b99300e32da6e2da3d2d96183 173 SUPERFAMILY SSF47240 4 161 9.45E-62 T 31-10-2018 IPR009078 Ferritin-like superfamily AF_0834 62875a8b99300e32da6e2da3d2d96183 173 Pfam PF00210 Ferritin-like domain 10 145 9.8E-44 T 31-10-2018 IPR008331 Ferritin/DPS protein domain GO:0006879|GO:0008199 AF_0834 62875a8b99300e32da6e2da3d2d96183 173 Gene3D G3DSA:1.20.1260.10 1 173 1.4E-60 T 31-10-2018 IPR012347 Ferritin-like AF_0372 54d3db477aa8957a2c1e7799869ec039 227 PIRSF PIRSF015626 3 221 9.9E-57 T 31-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AF_0372 54d3db477aa8957a2c1e7799869ec039 227 TIGRFAM TIGR00129 fdhD_narQ: formate dehydrogenase family accessory protein FdhD 8 225 9.5E-84 T 31-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AF_0372 54d3db477aa8957a2c1e7799869ec039 227 Pfam PF02634 FdhD/NarQ family 14 217 1.3E-45 T 31-10-2018 IPR003786 Sulfur carrier protein FdhD GO:0016783 AF_0372 54d3db477aa8957a2c1e7799869ec039 227 Gene3D G3DSA:3.10.20.10 14 87 4.0E-11 T 31-10-2018 AF_0372 54d3db477aa8957a2c1e7799869ec039 227 SUPERFAMILY SSF53927 10 216 5.72E-44 T 31-10-2018 IPR016193 Cytidine deaminase-like GO:0003824 AF_0372 54d3db477aa8957a2c1e7799869ec039 227 Gene3D G3DSA:3.40.140.10 90 221 3.7E-29 T 31-10-2018 AF_1677 ac756a63c3b3195285ce54c5279bed39 411 TIGRFAM TIGR00094 tRNA_TruD_broad: tRNA pseudouridine synthase, TruD family 1 410 2.5E-154 T 31-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AF_1677 ac756a63c3b3195285ce54c5279bed39 411 SUPERFAMILY SSF55120 3 408 7.77E-88 T 31-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AF_1677 ac756a63c3b3195285ce54c5279bed39 411 Hamap MF_01082 tRNA pseudouridine synthase D [truD]. 6 410 30.485 T 31-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AF_1677 ac756a63c3b3195285ce54c5279bed39 411 ProSitePatterns PS01268 Uncharacterized protein family UPF0024 signature. 78 91 - T 31-10-2018 IPR020119 Pseudouridine synthase TruD, conserved site GO:0001522|GO:0003723|GO:0009451|GO:0009982 Reactome: R-HSA-6782315 AF_1677 ac756a63c3b3195285ce54c5279bed39 411 Gene3D G3DSA:3.30.70.3160 39 124 2.9E-118 T 31-10-2018 AF_1677 ac756a63c3b3195285ce54c5279bed39 411 Gene3D G3DSA:3.30.2350.20 125 404 2.9E-118 T 31-10-2018 AF_1677 ac756a63c3b3195285ce54c5279bed39 411 PIRSF PIRSF037016 385 411 7.1E-4 T 31-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AF_1677 ac756a63c3b3195285ce54c5279bed39 411 PIRSF PIRSF037016 1 41 11.0 T 31-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AF_1677 ac756a63c3b3195285ce54c5279bed39 411 PIRSF PIRSF037016 34 384 1.4E-74 T 31-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AF_1677 ac756a63c3b3195285ce54c5279bed39 411 Gene3D G3DSA:1.10.1510.30 167 254 2.9E-118 T 31-10-2018 AF_1677 ac756a63c3b3195285ce54c5279bed39 411 Pfam PF01142 tRNA pseudouridine synthase D (TruD) 5 405 1.1E-140 T 31-10-2018 IPR001656 Pseudouridine synthase, TruD GO:0001522|GO:0003723|GO:0009451|GO:0009982 AF_2013 1f05b31d1567d799a40f023781c68043 440 Pfam PF00501 AMP-binding enzyme 86 340 1.3E-19 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_2013 1f05b31d1567d799a40f023781c68043 440 SUPERFAMILY SSF56801 33 406 1.27E-67 T 31-10-2018 AF_2013 1f05b31d1567d799a40f023781c68043 440 PIRSF PIRSF006444 5 439 1.9E-211 T 31-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 AF_2013 1f05b31d1567d799a40f023781c68043 440 Gene3D G3DSA:3.30.300.30 333 439 8.7E-36 T 31-10-2018 AF_2013 1f05b31d1567d799a40f023781c68043 440 Gene3D G3DSA:3.40.50.12780 2 332 1.2E-129 T 31-10-2018 AF_2013 1f05b31d1567d799a40f023781c68043 440 Pfam PF14535 AMP-binding enzyme C-terminal domain 341 437 2.6E-32 T 31-10-2018 IPR028154 AMP-dependent ligase, C-terminal AF_2314 8b0b353479949a7202f7bfaa81825674 147 ProSitePatterns PS00374 Methylated-DNA--protein-cysteine methyltransferase active site. 110 116 - T 31-10-2018 IPR001497 Methylated-DNA-[protein]-cysteine S-methyltransferase, active site GO:0003908|GO:0006281 Reactome: R-HSA-5657655 AF_2314 8b0b353479949a7202f7bfaa81825674 147 Pfam PF01035 6-O-methylguanine DNA methyltransferase, DNA binding domain 64 146 9.2E-25 T 31-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AF_2314 8b0b353479949a7202f7bfaa81825674 147 TIGRFAM TIGR00589 ogt: methylated-DNA--[protein]-cysteine S-methyltransferase 63 144 2.7E-24 T 31-10-2018 IPR014048 Methylated-DNA-[protein]-cysteine S-methyltransferase, DNA binding GO:0003824|GO:0006281 Reactome: R-HSA-5657655 AF_2314 8b0b353479949a7202f7bfaa81825674 147 SUPERFAMILY SSF46767 62 146 7.85E-23 T 31-10-2018 IPR036217 Methylated DNA-protein cysteine methyltransferase, DNA binding domain Reactome: R-HSA-5657655 AF_2314 8b0b353479949a7202f7bfaa81825674 147 Gene3D G3DSA:1.10.10.10 60 147 2.2E-29 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_2314 8b0b353479949a7202f7bfaa81825674 147 Hamap MF_00772 Methylated-DNA--protein-cysteine methyltransferase [ogt]. 2 145 36.905 T 31-10-2018 IPR023546 Methylated-DNA--protein-cysteine methyltransferase GO:0003824|GO:0006281 AF_1182 70233d3ad0d91779b6660ea1ff71cf35 118 PIRSF PIRSF004977 4 118 1.4E-53 T 31-10-2018 IPR012017 Uncharacterised conserved protein UCP004977 AF_1182 70233d3ad0d91779b6660ea1ff71cf35 118 Pfam PF09846 Uncharacterized protein conserved in archaea (DUF2073) 17 116 6.5E-42 T 31-10-2018 IPR012017 Uncharacterised conserved protein UCP004977 AF_1690 053d3158a1a55158dfeaa5e0384aaa95 136 Pfam PF01850 PIN domain 2 122 3.4E-17 T 31-10-2018 IPR002716 PIN domain AF_1690 053d3158a1a55158dfeaa5e0384aaa95 136 SUPERFAMILY SSF88723 2 124 8.13E-23 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_1690 053d3158a1a55158dfeaa5e0384aaa95 136 Gene3D G3DSA:3.40.50.1010 1 132 2.5E-25 T 31-10-2018 AF_0993 bb0068bececf2fecf2285c266fbc190d 337 Gene3D G3DSA:3.40.50.300 73 337 2.7E-81 T 31-10-2018 AF_0993 bb0068bececf2fecf2285c266fbc190d 337 Pfam PF14520 Helix-hairpin-helix domain 13 67 5.0E-13 T 31-10-2018 AF_0993 bb0068bececf2fecf2285c266fbc190d 337 TIGRFAM TIGR02236 recomb_radA: DNA repair and recombination protein RadA 13 326 1.3E-169 T 31-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 AF_0993 bb0068bececf2fecf2285c266fbc190d 337 SMART SM00382 107 296 4.6E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0993 bb0068bececf2fecf2285c266fbc190d 337 PIRSF PIRSF005856 2 330 9.8E-134 T 31-10-2018 IPR016467 DNA recombination and repair protein, RecA-like Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 AF_0993 bb0068bececf2fecf2285c266fbc190d 337 Hamap MF_00348 DNA repair and recombination protein RadA [radA]. 11 326 80.476 T 31-10-2018 IPR011938 DNA recombination/repair protein RadA GO:0003684|GO:0005524|GO:0006281|GO:0006310|GO:0008094 AF_0993 bb0068bececf2fecf2285c266fbc190d 337 SUPERFAMILY SSF47794 6 70 1.32E-14 T 31-10-2018 IPR010995 DNA repair Rad51/transcription factor NusA, alpha-helical GO:0000166 Reactome: R-HSA-912446 AF_0993 bb0068bececf2fecf2285c266fbc190d 337 SUPERFAMILY SSF52540 87 326 2.36E-57 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0993 bb0068bececf2fecf2285c266fbc190d 337 SMART SM00278 45 64 2400.0 T 31-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AF_0993 bb0068bececf2fecf2285c266fbc190d 337 SMART SM00278 12 31 0.0046 T 31-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AF_0993 bb0068bececf2fecf2285c266fbc190d 337 Gene3D G3DSA:1.10.150.20 1 71 1.5E-23 T 31-10-2018 AF_0993 bb0068bececf2fecf2285c266fbc190d 337 Pfam PF08423 Rad51 73 327 7.2E-92 T 31-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 AF_2312 836ea5f43c94cfbe5a93823ebbe0d090 171 SUPERFAMILY SSF47240 12 132 7.93E-35 T 31-10-2018 IPR009078 Ferritin-like superfamily AF_2312 836ea5f43c94cfbe5a93823ebbe0d090 171 SUPERFAMILY SSF57802 139 170 1.09E-10 T 31-10-2018 AF_2312 836ea5f43c94cfbe5a93823ebbe0d090 171 Gene3D G3DSA:1.20.1260.10 9 135 8.8E-42 T 31-10-2018 IPR012347 Ferritin-like AF_2312 836ea5f43c94cfbe5a93823ebbe0d090 171 Pfam PF02915 Rubrerythrin 15 129 4.6E-25 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 AF_2312 836ea5f43c94cfbe5a93823ebbe0d090 171 Gene3D G3DSA:2.20.28.10 137 171 4.6E-16 T 31-10-2018 AF_1025 2ddd34849fd25b3153cfde81bd40bef0 373 Gene3D G3DSA:3.40.50.720 1 187 3.4E-73 T 31-10-2018 AF_1025 2ddd34849fd25b3153cfde81bd40bef0 373 SUPERFAMILY SSF48179 301 371 2.98E-13 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_1025 2ddd34849fd25b3153cfde81bd40bef0 373 PIRSF PIRSF000105 1 303 8.1E-91 T 31-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 AF_1025 2ddd34849fd25b3153cfde81bd40bef0 373 PIRSF PIRSF000105 283 371 1.4E-6 T 31-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 AF_1025 2ddd34849fd25b3153cfde81bd40bef0 373 SUPERFAMILY SSF48179 185 286 9.35E-30 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_1025 2ddd34849fd25b3153cfde81bd40bef0 373 Gene3D G3DSA:1.10.1040.10 188 297 9.7E-30 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AF_1025 2ddd34849fd25b3153cfde81bd40bef0 373 SUPERFAMILY SSF51735 1 182 6.77E-63 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1025 2ddd34849fd25b3153cfde81bd40bef0 373 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 280 7.9E-29 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_1025 2ddd34849fd25b3153cfde81bd40bef0 373 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 303 371 4.1E-11 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_1025 2ddd34849fd25b3153cfde81bd40bef0 373 Gene3D G3DSA:1.10.1040.10 298 373 2.8E-26 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AF_1025 2ddd34849fd25b3153cfde81bd40bef0 373 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 5 183 6.4E-69 T 31-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_0651 d74b60f57f16e9a9041ed3b8bded63e9 76 Gene3D G3DSA:3.30.70.920 4 72 3.7E-19 T 31-10-2018 AF_0651 d74b60f57f16e9a9041ed3b8bded63e9 76 SUPERFAMILY SSF54909 2 72 2.91E-14 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel AF_0651 d74b60f57f16e9a9041ed3b8bded63e9 76 Pfam PF01037 Lrp/AsnC ligand binding domain 7 72 1.1E-12 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AF_0427 ff791711561b16c32e5d5fc57ffd03c9 63 SUPERFAMILY SSF54862 4 59 1.44E-16 T 31-10-2018 AF_0427 ff791711561b16c32e5d5fc57ffd03c9 63 PRINTS PR00352 3Fe-4S ferredoxin signature 45 57 8.9E-5 T 31-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AF_0427 ff791711561b16c32e5d5fc57ffd03c9 63 PRINTS PR00352 3Fe-4S ferredoxin signature 17 27 8.9E-5 T 31-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AF_0427 ff791711561b16c32e5d5fc57ffd03c9 63 PRINTS PR00352 3Fe-4S ferredoxin signature 6 17 8.9E-5 T 31-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AF_0427 ff791711561b16c32e5d5fc57ffd03c9 63 Pfam PF13237 4Fe-4S dicluster domain 4 53 3.2E-9 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0427 ff791711561b16c32e5d5fc57ffd03c9 63 Gene3D G3DSA:3.30.70.20 3 60 2.4E-19 T 31-10-2018 AF_1218 fa03d9b62d4aa5f20c25db81f579db23 97 Pfam PF10826 Protein of unknown function (DUF2551) 9 89 7.2E-31 T 31-10-2018 IPR020501 Uncharacterised protein family AF1218 AF_1218 fa03d9b62d4aa5f20c25db81f579db23 97 ProDom PD066267 AF1218 MA3722 MA2389 11 96 3.0E-35 T 31-10-2018 IPR020501 Uncharacterised protein family AF1218 AF_0204 5f897b034fade066dad34ee44f87244c 196 Pfam PF01976 Protein of unknown function DUF116 22 177 8.8E-44 T 31-10-2018 IPR002829 Protein of unknown function DUF116 AF_0204 5f897b034fade066dad34ee44f87244c 196 PIRSF PIRSF006594 1 184 1.4E-69 T 31-10-2018 IPR002829 Protein of unknown function DUF116 AF_1000 87cb225455da831db01efceb046192b3 247 Hamap MF_00193 NH(3)-dependent NAD(+) synthetase [nadE]. 2 241 54.218 T 31-10-2018 IPR022926 NH(3)-dependent NAD(+) synthetase GO:0008795|GO:0009435 KEGG: 00760+6.3.1.5 AF_1000 87cb225455da831db01efceb046192b3 247 Gene3D G3DSA:3.40.50.620 1 243 1.1E-87 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_1000 87cb225455da831db01efceb046192b3 247 Pfam PF02540 NAD synthase 7 238 3.9E-99 T 31-10-2018 IPR022310 NAD/GMP synthase AF_1000 87cb225455da831db01efceb046192b3 247 SUPERFAMILY SSF52402 2 240 2.19E-77 T 31-10-2018 AF_1000 87cb225455da831db01efceb046192b3 247 TIGRFAM TIGR00552 nadE: NAD+ synthetase 3 243 8.8E-103 T 31-10-2018 IPR003694 NAD(+) synthetase GO:0003952|GO:0005524|GO:0009435 KEGG: 00760+6.3.1.5|Reactome: R-HSA-196807 AF_2356 7504836c578656e6a50161fe76e4e83c 147 Pfam PF01878 EVE domain 2 144 1.7E-26 T 31-10-2018 IPR002740 EVE domain AF_2356 7504836c578656e6a50161fe76e4e83c 147 Hamap MF_00771 UPF0310 protein . 1 146 26.73 T 31-10-2018 IPR022996 Uncharacterised protein family UPF0310 AF_2356 7504836c578656e6a50161fe76e4e83c 147 Gene3D G3DSA:3.10.590.10 1 145 3.3E-56 T 31-10-2018 AF_2356 7504836c578656e6a50161fe76e4e83c 147 SUPERFAMILY SSF88697 1 145 1.49E-41 T 31-10-2018 IPR015947 PUA-like superfamily AF_1649 93b76cd19cbcb93a30c583870541e9cd 156 Pfam PF00037 4Fe-4S binding domain 74 93 9.9E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1649 93b76cd19cbcb93a30c583870541e9cd 156 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 80 91 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1649 93b76cd19cbcb93a30c583870541e9cd 156 Pfam PF04060 Putative Fe-S cluster 12 44 2.7E-14 T 31-10-2018 IPR007202 4Fe-4S domain GO:0051536 AF_1649 93b76cd19cbcb93a30c583870541e9cd 156 SUPERFAMILY SSF54862 9 153 5.76E-12 T 31-10-2018 AF_1649 93b76cd19cbcb93a30c583870541e9cd 156 Gene3D G3DSA:3.30.70.20 73 153 3.5E-9 T 31-10-2018 AF_1649 93b76cd19cbcb93a30c583870541e9cd 156 Gene3D G3DSA:1.10.15.40 2 57 2.3E-21 T 31-10-2018 AF_0636 45faea59e55941cd602103c109dd885c 679 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 128 599 3.2E-123 T 31-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AF_0636 45faea59e55941cd602103c109dd885c 679 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 29 674 9.5E-241 T 31-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ AF_1869 db856fa89d996a76ff4fda8c8fd7f64f 213 TIGRFAM TIGR01884 cas_HTH: CRISPR locus-related DNA-binding protein 5 208 1.8E-67 T 31-10-2018 IPR010163 CRISPR locus-related putative DNA-binding protein Csa3 AF_1869 db856fa89d996a76ff4fda8c8fd7f64f 213 Gene3D G3DSA:3.40.50.11700 1 128 3.9E-10 T 31-10-2018 AF_1869 db856fa89d996a76ff4fda8c8fd7f64f 213 SUPERFAMILY SSF46785 139 198 2.63E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1869 db856fa89d996a76ff4fda8c8fd7f64f 213 Gene3D G3DSA:1.10.10.10 139 209 2.3E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1869 db856fa89d996a76ff4fda8c8fd7f64f 213 Pfam PF01022 Bacterial regulatory protein, arsR family 151 193 9.5E-12 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_0435 496d691d977797325d9d353d1cc820f9 256 Gene3D G3DSA:3.90.226.10 2 198 4.1E-73 T 31-10-2018 AF_0435 496d691d977797325d9d353d1cc820f9 256 SUPERFAMILY SSF52096 2 256 1.24E-91 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AF_0435 496d691d977797325d9d353d1cc820f9 256 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 97 117 - T 31-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 AF_0435 496d691d977797325d9d353d1cc820f9 256 Pfam PF00378 Enoyl-CoA hydratase/isomerase 11 255 8.6E-76 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AF_0435 496d691d977797325d9d353d1cc820f9 256 Gene3D G3DSA:1.10.12.10 199 256 3.2E-26 T 31-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AF_2269 b0106eacb388a0511f182010e923c2db 254 Hamap MF_02040 Iron-sulfur cluster carrier protein. 12 249 34.34 T 31-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein AF_2269 b0106eacb388a0511f182010e923c2db 254 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 20 240 6.3E-90 T 31-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 AF_2269 b0106eacb388a0511f182010e923c2db 254 Gene3D G3DSA:3.40.50.300 1 252 3.2E-88 T 31-10-2018 AF_2269 b0106eacb388a0511f182010e923c2db 254 SUPERFAMILY SSF52540 8 240 4.36E-55 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2269 b0106eacb388a0511f182010e923c2db 254 ProSitePatterns PS01215 Mrp family signature. 126 142 - T 31-10-2018 IPR000808 Mrp, conserved site GO:0005524 AF_1067 ccd317a05892671b80d0cdd856486e72 89 Gene3D G3DSA:3.30.110.20 1 88 1.1E-36 T 31-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 AF_1067 ccd317a05892671b80d0cdd856486e72 89 SUPERFAMILY SSF82704 2 88 1.02E-25 T 31-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 AF_1067 ccd317a05892671b80d0cdd856486e72 89 Pfam PF01918 Alba 4 67 5.3E-21 T 31-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 AF_1067 ccd317a05892671b80d0cdd856486e72 89 PIRSF PIRSF028732 1 89 1.8E-40 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 AF_1067 ccd317a05892671b80d0cdd856486e72 89 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 8 89 2.0E-40 T 31-10-2018 AF_1067 ccd317a05892671b80d0cdd856486e72 89 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 3 88 6.1E-49 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 AF_1067 ccd317a05892671b80d0cdd856486e72 89 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 88 26.377 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 AF_0662 9909df11f5c4d450fb93832f2b89d9a9 747 Pfam PF02662 Methyl-viologen-reducing hydrogenase, delta subunit 616 740 1.9E-39 T 31-10-2018 IPR003813 F420-non-reducing hydrogenase iron-sulfur subunit D GO:0055114 AF_0662 9909df11f5c4d450fb93832f2b89d9a9 747 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 130 249 4.0E-9 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AF_0662 9909df11f5c4d450fb93832f2b89d9a9 747 Pfam PF13187 4Fe-4S dicluster domain 535 580 7.5E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0662 9909df11f5c4d450fb93832f2b89d9a9 747 Gene3D G3DSA:3.30.70.20 531 599 7.5E-11 T 31-10-2018 AF_0662 9909df11f5c4d450fb93832f2b89d9a9 747 Gene3D G3DSA:3.50.50.60 124 278 1.4E-16 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0662 9909df11f5c4d450fb93832f2b89d9a9 747 SUPERFAMILY SSF54862 529 591 4.89E-16 T 31-10-2018 AF_0662 9909df11f5c4d450fb93832f2b89d9a9 747 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 235 253 4.4E-6 T 31-10-2018 AF_0662 9909df11f5c4d450fb93832f2b89d9a9 747 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 132 151 4.4E-6 T 31-10-2018 AF_0662 9909df11f5c4d450fb93832f2b89d9a9 747 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 390 406 4.4E-6 T 31-10-2018 AF_0662 9909df11f5c4d450fb93832f2b89d9a9 747 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 536 547 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0662 9909df11f5c4d450fb93832f2b89d9a9 747 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 480 487 5.7E-5 T 31-10-2018 AF_0662 9909df11f5c4d450fb93832f2b89d9a9 747 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 131 153 5.7E-5 T 31-10-2018 AF_0662 9909df11f5c4d450fb93832f2b89d9a9 747 SUPERFAMILY SSF51971 129 509 1.11E-29 T 31-10-2018 AF_0662 9909df11f5c4d450fb93832f2b89d9a9 747 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 566 577 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1489 a04b0c0091bbbc005e19f622ddba7018 623 Pfam PF00037 4Fe-4S binding domain 596 618 1.8E-6 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1489 a04b0c0091bbbc005e19f622ddba7018 623 SUPERFAMILY SSF52518 370 577 9.26E-32 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold AF_1489 a04b0c0091bbbc005e19f622ddba7018 623 Pfam PF01855 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg 25 193 5.6E-15 T 31-10-2018 IPR002880 Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0055114 AF_1489 a04b0c0091bbbc005e19f622ddba7018 623 SUPERFAMILY SSF52518 11 248 1.95E-57 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold AF_1489 a04b0c0091bbbc005e19f622ddba7018 623 SUPERFAMILY SSF52922 233 347 7.2E-13 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AF_1489 a04b0c0091bbbc005e19f622ddba7018 623 Gene3D G3DSA:3.40.50.970 383 567 1.0E-18 T 31-10-2018 AF_1489 a04b0c0091bbbc005e19f622ddba7018 623 TIGRFAM TIGR03336 IOR_alpha: indolepyruvate ferredoxin oxidoreductase, alpha subunit 13 617 8.0E-234 T 31-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 AF_1489 a04b0c0091bbbc005e19f622ddba7018 623 Gene3D G3DSA:3.30.70.20 568 621 4.4E-8 T 31-10-2018 AF_1489 a04b0c0091bbbc005e19f622ddba7018 623 Gene3D G3DSA:3.40.50.970 2 196 8.9E-55 T 31-10-2018 AF_1489 a04b0c0091bbbc005e19f622ddba7018 623 SUPERFAMILY SSF54862 558 618 1.04E-10 T 31-10-2018 AF_1489 a04b0c0091bbbc005e19f622ddba7018 623 PIRSF PIRSF006439 2 623 7.1E-272 T 31-10-2018 IPR017721 Indolepyruvate ferredoxin oxidoreductase, alpha subunit GO:0043805|GO:0055114 AF_1489 a04b0c0091bbbc005e19f622ddba7018 623 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 602 613 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1489 a04b0c0091bbbc005e19f622ddba7018 623 Gene3D G3DSA:3.40.50.920 235 333 7.7E-8 T 31-10-2018 IPR009014 Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II GO:0003824 AF_1489 a04b0c0091bbbc005e19f622ddba7018 623 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 404 545 5.5E-28 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AF_0943 d2365861542f49ac0d89a2a91b1c4740 225 Gene3D G3DSA:3.30.70.260 126 204 7.2E-74 T 31-10-2018 AF_0943 d2365861542f49ac0d89a2a91b1c4740 225 Gene3D G3DSA:3.40.50.1360 7 219 7.2E-74 T 31-10-2018 AF_0943 d2365861542f49ac0d89a2a91b1c4740 225 TIGRFAM TIGR00021 rpiA: ribose 5-phosphate isomerase A 6 219 7.1E-69 T 31-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 AF_0943 d2365861542f49ac0d89a2a91b1c4740 225 SUPERFAMILY SSF75445 129 206 2.49E-21 T 31-10-2018 AF_0943 d2365861542f49ac0d89a2a91b1c4740 225 SUPERFAMILY SSF100950 6 176 1.62E-39 T 31-10-2018 IPR037171 NagB/RpiA transferase-like AF_0943 d2365861542f49ac0d89a2a91b1c4740 225 Pfam PF06026 Ribose 5-phosphate isomerase A (phosphoriboisomerase A) 51 219 6.1E-59 T 31-10-2018 IPR004788 Ribose 5-phosphate isomerase, type A GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 AF_0943 d2365861542f49ac0d89a2a91b1c4740 225 Hamap MF_00170 Ribose-5-phosphate isomerase A [rpiA]. 2 225 33.72 T 31-10-2018 IPR020672 Ribose-5-phosphate isomerase, type A, subgroup GO:0004751|GO:0009052 KEGG: 00030+5.3.1.6|KEGG: 00051+5.3.1.6|KEGG: 00710+5.3.1.6|MetaCyc: PWY-1861|MetaCyc: PWY-5723|Reactome: R-HSA-5659996|Reactome: R-HSA-6791461|Reactome: R-HSA-71336 AF_0903 290c6053bee021e8e64158b35a429ed2 165 Gene3D G3DSA:1.10.10.10 11 104 4.4E-23 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0903 290c6053bee021e8e64158b35a429ed2 165 SUPERFAMILY SSF46785 25 102 8.19E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1381 8aba17257b0a8a8c22585629ca8cee47 353 Gene3D G3DSA:4.10.480.10 228 336 1.5E-27 T 31-10-2018 IPR037148 [NiFe]-hydrogenase, small subunit, C-terminal domain superfamily AF_1381 8aba17257b0a8a8c22585629ca8cee47 353 TIGRFAM TIGR00391 hydA: hydrogenase (NiFe) small subunit (hydA) 5 344 1.6E-67 T 31-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 AF_1381 8aba17257b0a8a8c22585629ca8cee47 353 PIRSF PIRSF000310 1 352 2.4E-118 T 31-10-2018 IPR001821 [NiFe]-hydrogenase, small subunit GO:0008901|GO:0009375|GO:0051536|GO:0055114 AF_1381 8aba17257b0a8a8c22585629ca8cee47 353 SUPERFAMILY SSF56770 41 306 4.71E-66 T 31-10-2018 AF_1381 8aba17257b0a8a8c22585629ca8cee47 353 Gene3D G3DSA:3.40.50.700 28 224 4.4E-55 T 31-10-2018 IPR037024 [NiFe]-hydrogenase, small subunit, N-terminal domain superfamily AF_1381 8aba17257b0a8a8c22585629ca8cee47 353 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 51 206 6.1E-30 T 31-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1381 8aba17257b0a8a8c22585629ca8cee47 353 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 5 33 3.0E-5 T 31-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal AF_1381 8aba17257b0a8a8c22585629ca8cee47 353 Pfam PF14720 NiFe/NiFeSe hydrogenase small subunit C-terminal 225 305 1.1E-28 T 31-10-2018 IPR027394 Cytochrome-c3 hydrogenase, C-terminal AF_1381 8aba17257b0a8a8c22585629ca8cee47 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 279 292 7.7E-25 T 31-10-2018 AF_1381 8aba17257b0a8a8c22585629ca8cee47 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 36 58 7.7E-25 T 31-10-2018 AF_1381 8aba17257b0a8a8c22585629ca8cee47 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 154 178 7.7E-25 T 31-10-2018 AF_1381 8aba17257b0a8a8c22585629ca8cee47 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 187 210 7.7E-25 T 31-10-2018 AF_1381 8aba17257b0a8a8c22585629ca8cee47 353 PRINTS PR00614 Ni-Fe hydrogenase small subunit signature 251 277 7.7E-25 T 31-10-2018 AF_1114 a011e40d976bfda1611f31651aa0e939 110 ProDom PD006052 RIBOSOMAL S24 40S RIBONUCLEOPROTEIN S24E 30S S24 CDNA RIKEN ACETYLATION 14 82 2.0E-34 T 31-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1114 a011e40d976bfda1611f31651aa0e939 110 ProSitePatterns PS00529 Ribosomal protein S24e signature. 62 84 - T 31-10-2018 IPR018098 Ribosomal S24e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1114 a011e40d976bfda1611f31651aa0e939 110 Pfam PF01282 Ribosomal protein S24e 27 99 1.2E-25 T 31-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1114 a011e40d976bfda1611f31651aa0e939 110 Hamap MF_00545 30S ribosomal protein S24e [rps24e]. 4 102 20.571 T 31-10-2018 IPR001976 Ribosomal protein S24e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1114 a011e40d976bfda1611f31651aa0e939 110 SUPERFAMILY SSF54189 4 104 8.63E-31 T 31-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1114 a011e40d976bfda1611f31651aa0e939 110 Gene3D G3DSA:3.30.70.330 4 104 6.7E-34 T 31-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily AF_0750 b1b45460113220ce91788493dc7837a9 245 SUPERFAMILY SSF52518 4 207 1.11E-63 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold AF_0750 b1b45460113220ce91788493dc7837a9 245 Gene3D G3DSA:3.40.50.970 17 212 2.2E-20 T 31-10-2018 AF_0750 b1b45460113220ce91788493dc7837a9 245 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 39 186 8.8E-29 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AF_0484 37ca63619c74f819077e145fab7364dd 378 Gene3D G3DSA:3.40.50.10990 185 354 5.0E-66 T 31-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AF_0484 37ca63619c74f819077e145fab7364dd 378 PIRSF PIRSF001259 1 378 1.4E-106 T 31-10-2018 AF_0484 37ca63619c74f819077e145fab7364dd 378 Hamap MF_00179 GTP cyclohydrolase-2 [ribA]. 183 376 36.821 T 31-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AF_0484 37ca63619c74f819077e145fab7364dd 378 Pfam PF00925 GTP cyclohydrolase II 187 348 2.1E-65 T 31-10-2018 IPR032677 GTP cyclohydrolase II KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AF_0484 37ca63619c74f819077e145fab7364dd 378 SUPERFAMILY SSF55821 2 185 1.99E-36 T 31-10-2018 IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily AF_0484 37ca63619c74f819077e145fab7364dd 378 Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase 3 176 8.2E-33 T 31-10-2018 IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB GO:0008686|GO:0009231 KEGG: 00740+4.1.99.12|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AF_0484 37ca63619c74f819077e145fab7364dd 378 SUPERFAMILY SSF142695 183 348 5.23E-58 T 31-10-2018 IPR036144 RibA-like superfamily KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AF_0484 37ca63619c74f819077e145fab7364dd 378 TIGRFAM TIGR00505 ribA: GTP cyclohydrolase II 186 374 1.2E-85 T 31-10-2018 IPR000926 GTP cyclohydrolase II, RibA GO:0003935|GO:0009231 KEGG: 00740+3.5.4.25|KEGG: 00790+3.5.4.25|MetaCyc: PWY-6168|MetaCyc: PWY-7539|MetaCyc: PWY-7991 AF_0484 37ca63619c74f819077e145fab7364dd 378 Gene3D G3DSA:3.90.870.10 1 184 1.0E-30 T 31-10-2018 AF_0785 e662c59c52544b0dcff6aeeca3fb3f72 342 TIGRFAM TIGR00341 TIGR00341: TIGR00341 family protein 13 341 4.6E-148 T 31-10-2018 AF_0785 e662c59c52544b0dcff6aeeca3fb3f72 342 TIGRFAM TIGR00271 TIGR00271: uncharacterized hydrophobic domain 124 299 2.0E-54 T 31-10-2018 AF_0785 e662c59c52544b0dcff6aeeca3fb3f72 342 Pfam PF04087 Domain of unknown function (DUF389) 157 293 1.6E-29 T 31-10-2018 IPR005240 Protein of unknown function DUF389 AF_0034 b3195bd60874003991837fb9c236f928 417 Pfam PF00108 Thiolase, N-terminal domain 38 248 2.2E-18 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AF_0034 b3195bd60874003991837fb9c236f928 417 Gene3D G3DSA:3.40.47.10 37 416 1.2E-113 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0034 b3195bd60874003991837fb9c236f928 417 Pfam PF02803 Thiolase, C-terminal domain 290 383 2.0E-6 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 AF_0034 b3195bd60874003991837fb9c236f928 417 SUPERFAMILY SSF53901 278 404 6.17E-25 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0034 b3195bd60874003991837fb9c236f928 417 PIRSF PIRSF000429 32 416 2.6E-85 T 31-10-2018 IPR002155 Thiolase GO:0016747 AF_0034 b3195bd60874003991837fb9c236f928 417 SUPERFAMILY SSF53901 34 254 3.06E-42 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0893 282deafe261e02147cde4202806a7384 334 SUPERFAMILY SSF55874 201 331 1.17E-26 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_0893 282deafe261e02147cde4202806a7384 334 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 17 128 1.7E-18 T 31-10-2018 IPR000014 PAS domain AF_0893 282deafe261e02147cde4202806a7384 334 Gene3D G3DSA:3.30.450.20 10 136 2.4E-20 T 31-10-2018 AF_0893 282deafe261e02147cde4202806a7384 334 Pfam PF13426 PAS domain 19 121 7.2E-14 T 31-10-2018 IPR000014 PAS domain AF_0893 282deafe261e02147cde4202806a7384 334 Gene3D G3DSA:3.30.565.10 199 334 2.5E-28 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_0893 282deafe261e02147cde4202806a7384 334 SMART SM00091 7 73 7.5E-4 T 31-10-2018 IPR000014 PAS domain AF_0893 282deafe261e02147cde4202806a7384 334 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 232 332 1.8E-21 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_0893 282deafe261e02147cde4202806a7384 334 SUPERFAMILY SSF55785 12 121 9.77E-18 T 31-10-2018 IPR035965 PAS domain superfamily AF_0893 282deafe261e02147cde4202806a7384 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 317 330 1.7E-11 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_0893 282deafe261e02147cde4202806a7384 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 293 311 1.7E-11 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_0893 282deafe261e02147cde4202806a7384 334 PRINTS PR00344 Bacterial sensor protein C-terminal signature 265 279 1.7E-11 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_0893 282deafe261e02147cde4202806a7384 334 SMART SM00086 82 122 0.0076 T 31-10-2018 IPR001610 PAC motif AF_0893 282deafe261e02147cde4202806a7384 334 SMART SM00387 229 333 6.1E-25 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_0302 c94efdcd1c8928197d077c1bc92ba1e2 324 Gene3D G3DSA:1.20.5.100 200 231 5.9E-17 T 31-10-2018 AF_0302 c94efdcd1c8928197d077c1bc92ba1e2 324 Gene3D G3DSA:3.40.50.720 1 198 5.7E-70 T 31-10-2018 AF_0302 c94efdcd1c8928197d077c1bc92ba1e2 324 Pfam PF00984 UDP-glucose/GDP-mannose dehydrogenase family, central domain 201 293 4.5E-40 T 31-10-2018 IPR014026 UDP-glucose/GDP-mannose dehydrogenase, dimerisation GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AF_0302 c94efdcd1c8928197d077c1bc92ba1e2 324 Gene3D G3DSA:3.40.50.720 232 323 3.3E-26 T 31-10-2018 AF_0302 c94efdcd1c8928197d077c1bc92ba1e2 324 SUPERFAMILY SSF51735 2 191 2.66E-48 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0302 c94efdcd1c8928197d077c1bc92ba1e2 324 SUPERFAMILY SSF48179 201 295 4.76E-34 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_0302 c94efdcd1c8928197d077c1bc92ba1e2 324 Pfam PF03721 UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain 2 187 1.1E-63 T 31-10-2018 IPR001732 UDP-glucose/GDP-mannose dehydrogenase, N-terminal GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-173599 AF_0302 c94efdcd1c8928197d077c1bc92ba1e2 324 TIGRFAM TIGR03026 NDP-sugDHase: nucleotide sugar dehydrogenase 2 312 4.3E-115 T 31-10-2018 IPR017476 UDP-glucose/GDP-mannose dehydrogenase GO:0016616|GO:0055114 Reactome: R-HSA-173599 AF_0251 3d9dcc0e4baffb6e04a41cfab4621fa6 394 Gene3D G3DSA:1.20.58.1130 42 241 1.8E-17 T 31-10-2018 AF_0251 3d9dcc0e4baffb6e04a41cfab4621fa6 394 Gene3D G3DSA:1.20.1420.30 61 349 1.8E-17 T 31-10-2018 AF_0251 3d9dcc0e4baffb6e04a41cfab4621fa6 394 Pfam PF01699 Sodium/calcium exchanger protein 209 354 9.1E-15 T 31-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 AF_0251 3d9dcc0e4baffb6e04a41cfab4621fa6 394 Pfam PF01699 Sodium/calcium exchanger protein 39 181 5.3E-22 T 31-10-2018 IPR004837 Sodium/calcium exchanger membrane region GO:0016021|GO:0055085 Reactome: R-HSA-425561 AF_2228 df5288626c58f7f94cd9d1da55b6056a 115 Gene3D G3DSA:3.30.1420.10 1 45 1.7E-27 T 31-10-2018 AF_2228 df5288626c58f7f94cd9d1da55b6056a 115 Pfam PF04358 DsrC like protein 5 115 3.6E-42 T 31-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE AF_2228 df5288626c58f7f94cd9d1da55b6056a 115 PIRSF PIRSF006223 4 115 3.1E-40 T 31-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE AF_2228 df5288626c58f7f94cd9d1da55b6056a 115 SUPERFAMILY SSF69721 2 115 1.1E-39 T 31-10-2018 IPR025526 DsrC-like domain superfamily AF_2228 df5288626c58f7f94cd9d1da55b6056a 115 Gene3D G3DSA:1.10.10.370 46 115 2.2E-33 T 31-10-2018 AF_2228 df5288626c58f7f94cd9d1da55b6056a 115 TIGRFAM TIGR03342 dsrC_tusE_dsvC: sulfur relay protein, TusE/DsrC/DsvC family 4 115 3.1E-46 T 31-10-2018 IPR007453 Sulphur transfer protein DsrC/TusE AF_0290 1e7d6301077e36767021c2acf2a96355 243 Pfam PF00005 ABC transporter 43 174 2.2E-23 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0290 1e7d6301077e36767021c2acf2a96355 243 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_0290 1e7d6301077e36767021c2acf2a96355 243 Gene3D G3DSA:3.40.50.300 19 243 2.4E-49 T 31-10-2018 AF_0290 1e7d6301077e36767021c2acf2a96355 243 SMART SM00382 52 241 2.5E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0290 1e7d6301077e36767021c2acf2a96355 243 SUPERFAMILY SSF52540 29 235 3.04E-48 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2087 08de159db34a91eeec5d43f1f1f42533 210 Gene3D G3DSA:3.40.50.150 37 210 1.1E-69 T 31-10-2018 AF_2087 08de159db34a91eeec5d43f1f1f42533 210 Gene3D G3DSA:3.30.200.20 1 36 1.4E-28 T 31-10-2018 AF_2087 08de159db34a91eeec5d43f1f1f42533 210 PRINTS PR00052 Fibrillarin signature 82 99 2.4E-36 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 AF_2087 08de159db34a91eeec5d43f1f1f42533 210 PRINTS PR00052 Fibrillarin signature 188 209 2.4E-36 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 AF_2087 08de159db34a91eeec5d43f1f1f42533 210 PRINTS PR00052 Fibrillarin signature 32 51 2.4E-36 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 AF_2087 08de159db34a91eeec5d43f1f1f42533 210 PRINTS PR00052 Fibrillarin signature 107 136 2.4E-36 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 AF_2087 08de159db34a91eeec5d43f1f1f42533 210 PRINTS PR00052 Fibrillarin signature 137 166 2.4E-36 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 AF_2087 08de159db34a91eeec5d43f1f1f42533 210 SUPERFAMILY SSF53335 9 206 1.66E-39 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_2087 08de159db34a91eeec5d43f1f1f42533 210 Hamap MF_00351 Fibrillarin-like rRNA/tRNA 2'-O-methyltransferase [flpA]. 7 210 39.375 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 AF_2087 08de159db34a91eeec5d43f1f1f42533 210 PIRSF PIRSF006540 2 210 1.4E-81 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 AF_2087 08de159db34a91eeec5d43f1f1f42533 210 Pfam PF01269 Fibrillarin 4 207 2.5E-68 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 AF_2087 08de159db34a91eeec5d43f1f1f42533 210 SMART SM01206 1 210 5.7E-110 T 31-10-2018 IPR000692 Fibrillarin GO:0003723|GO:0006364|GO:0008168 AF_2087 08de159db34a91eeec5d43f1f1f42533 210 ProSitePatterns PS00566 Fibrillarin signature. 82 95 - T 31-10-2018 IPR020813 Fibrillarin, conserved site GO:0003723|GO:0006364|GO:0008168 AF_0645 7e645c693337ecadf914bc0a1ae6da1a 128 Pfam PF01287 Eukaryotic elongation factor 5A hypusine, DNA-binding OB fold 68 124 2.1E-8 T 31-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 AF_0645 7e645c693337ecadf914bc0a1ae6da1a 128 TIGRFAM TIGR00037 eIF_5A: translation elongation factor IF5A 1 127 2.4E-64 T 31-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 AF_0645 7e645c693337ecadf914bc0a1ae6da1a 128 ProSitePatterns PS00302 Eukaryotic initiation factor 5A hypusine signature. 33 40 - T 31-10-2018 IPR019769 Translation elongation factor, IF5A, hypusine site GO:0003723|GO:0003746|GO:0043022|GO:0045901|GO:0045905 AF_0645 7e645c693337ecadf914bc0a1ae6da1a 128 SUPERFAMILY SSF50104 4 76 4.41E-21 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily AF_0645 7e645c693337ecadf914bc0a1ae6da1a 128 Gene3D G3DSA:2.30.30.30 1 68 4.4E-28 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 AF_0645 7e645c693337ecadf914bc0a1ae6da1a 128 SMART SM01376 68 128 2.4E-19 T 31-10-2018 IPR020189 Translation elongation factor, IF5A C-terminal GO:0003723|GO:0003746|GO:0006452|GO:0043022|GO:0045901|GO:0045905 AF_0645 7e645c693337ecadf914bc0a1ae6da1a 128 Hamap MF_00085 Translation initiation factor 5A [eif5a]. 1 127 37.085 T 31-10-2018 IPR022847 Translation elongation factor IF5A, archaeal AF_0645 7e645c693337ecadf914bc0a1ae6da1a 128 PIRSF PIRSF003025 1 128 1.8E-49 T 31-10-2018 IPR001884 Translation elongation factor IF5A-like GO:0003723|GO:0003746|GO:0043022|GO:0045901 AF_0645 7e645c693337ecadf914bc0a1ae6da1a 128 SUPERFAMILY SSF50249 68 124 4.24E-12 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0645 7e645c693337ecadf914bc0a1ae6da1a 128 Gene3D G3DSA:2.40.50.140 69 128 1.0E-24 T 31-10-2018 AF_0927 a1470877cfda352eb32f654c70fb51df 188 ProDom PD016827 ARCHAEA ST0532 APE1937 VNG0250C MM2281 PAE3406 AF0927 UNCHARACTERIZED C3_0043 MJ0209 1 184 5.0E-101 T 31-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase AF_0927 a1470877cfda352eb32f654c70fb51df 188 Pfam PF02006 Phosphopantothenate/pantothenate synthetase 1 173 7.3E-74 T 31-10-2018 IPR002855 Phosphopantoate/pantothenate synthetase AF_0927 a1470877cfda352eb32f654c70fb51df 188 Gene3D G3DSA:3.40.50.12640 1 187 2.9E-74 T 31-10-2018 IPR038138 Phosphopantoate/pantothenate synthetase superfamily AF_0671 93050124ade18a461b597ded00898589 414 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 120 9.4E-21 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AF_0671 93050124ade18a461b597ded00898589 414 SUPERFAMILY SSF56645 5 230 6.15E-61 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AF_0671 93050124ade18a461b597ded00898589 414 Gene3D G3DSA:1.10.540.10 1 123 1.4E-24 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AF_0671 93050124ade18a461b597ded00898589 414 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 233 382 1.3E-37 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AF_0671 93050124ade18a461b597ded00898589 414 Gene3D G3DSA:1.20.140.10 237 403 8.5E-49 T 31-10-2018 AF_0671 93050124ade18a461b597ded00898589 414 Gene3D G3DSA:2.40.110.10 125 236 1.3E-31 T 31-10-2018 AF_0671 93050124ade18a461b597ded00898589 414 SUPERFAMILY SSF47203 231 387 1.27E-45 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AF_0671 93050124ade18a461b597ded00898589 414 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 220 9.5E-21 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AF_0671 93050124ade18a461b597ded00898589 414 ProSitePatterns PS00072 Acyl-CoA dehydrogenases signature 1. 127 139 - T 31-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AF_0176 a7444238d8c747758dd60b4c1dd0133d 896 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 39 95 2.2E-10 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_0176 a7444238d8c747758dd60b4c1dd0133d 896 Gene3D G3DSA:3.40.50.740 33 893 5.6E-234 T 31-10-2018 AF_0176 a7444238d8c747758dd60b4c1dd0133d 896 SMART SM00926 39 96 1.1E-4 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_0176 a7444238d8c747758dd60b4c1dd0133d 896 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 3 25 3.2E-4 T 31-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal AF_0176 a7444238d8c747758dd60b4c1dd0133d 896 ProSitePatterns PS00551 Prokaryotic molybdopterin oxidoreductases signature 1. 44 62 - T 31-10-2018 IPR027467 Molybdopterin oxidoreductase, molybdopterin cofactor binding site GO:0051539 AF_0176 a7444238d8c747758dd60b4c1dd0133d 896 SUPERFAMILY SSF53706 38 600 7.46E-150 T 31-10-2018 AF_0176 a7444238d8c747758dd60b4c1dd0133d 896 SUPERFAMILY SSF50692 761 894 6.1E-33 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AF_0176 a7444238d8c747758dd60b4c1dd0133d 896 Pfam PF01568 Molydopterin dinucleotide binding domain 770 869 9.9E-25 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AF_0176 a7444238d8c747758dd60b4c1dd0133d 896 Pfam PF00384 Molybdopterin oxidoreductase 99 606 7.0E-73 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1512 a3c47dc30b782f35e917ed3f6f74a11d 250 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 150 178 6.8E-30 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AF_1512 a3c47dc30b782f35e917ed3f6f74a11d 250 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 84 102 6.8E-30 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AF_1512 a3c47dc30b782f35e917ed3f6f74a11d 250 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 102 128 6.8E-30 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AF_1512 a3c47dc30b782f35e917ed3f6f74a11d 250 PRINTS PR01840 Bacterial Sec-independent translocation TatC protein family signature 11 38 6.8E-30 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AF_1512 a3c47dc30b782f35e917ed3f6f74a11d 250 TIGRFAM TIGR00945 tatC: twin arginine-targeting protein translocase TatC 12 223 5.7E-58 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AF_1512 a3c47dc30b782f35e917ed3f6f74a11d 250 Pfam PF00902 Sec-independent protein translocase protein (TatC) 14 214 2.0E-40 T 31-10-2018 IPR002033 Sec-independent periplasmic protein translocase TatC GO:0016021 AF_2125 2aba6f68690ed93809fc26f215f34076 325 Pfam PF01925 Sulfite exporter TauE/SafE 7 312 5.1E-29 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AF_2418 0a5ca9fe282f532d6e354dfbf4fb8749 208 SUPERFAMILY SSF47781 149 208 2.1E-17 T 31-10-2018 IPR010994 RuvA domain 2-like AF_2418 0a5ca9fe282f532d6e354dfbf4fb8749 208 Pfam PF02732 ERCC4 domain 4 107 1.9E-13 T 31-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 AF_2418 0a5ca9fe282f532d6e354dfbf4fb8749 208 Gene3D G3DSA:1.10.150.20 141 208 1.6E-21 T 31-10-2018 AF_2418 0a5ca9fe282f532d6e354dfbf4fb8749 208 Gene3D G3DSA:3.40.50.10130 1 139 1.5E-26 T 31-10-2018 AF_2418 0a5ca9fe282f532d6e354dfbf4fb8749 208 SMART SM00278 155 174 0.0028 T 31-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AF_2418 0a5ca9fe282f532d6e354dfbf4fb8749 208 SMART SM00278 187 206 0.076 T 31-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AF_2418 0a5ca9fe282f532d6e354dfbf4fb8749 208 SMART SM00891 1 84 4.7E-17 T 31-10-2018 IPR006166 ERCC4 domain GO:0003677|GO:0004518 Reactome: R-HSA-6783310 AF_2418 0a5ca9fe282f532d6e354dfbf4fb8749 208 SUPERFAMILY SSF52980 2 107 2.6E-19 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AF_2418 0a5ca9fe282f532d6e354dfbf4fb8749 208 Pfam PF12826 Helix-hairpin-helix motif 159 208 2.4E-13 T 31-10-2018 AF_1375 5c03e4f2cbfec725ed602b276f3028c4 294 Pfam PF02754 Cysteine-rich domain 5 87 1.5E-11 T 31-10-2018 IPR004017 Cysteine-rich domain AF_1375 5c03e4f2cbfec725ed602b276f3028c4 294 Pfam PF02754 Cysteine-rich domain 147 238 9.4E-20 T 31-10-2018 IPR004017 Cysteine-rich domain AF_1100 dae99c3eb8dc4db0ed46b787d29aa48e 802 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 444 455 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1100 dae99c3eb8dc4db0ed46b787d29aa48e 802 SUPERFAMILY SSF56821 13 734 1.01E-165 T 31-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 AF_1100 dae99c3eb8dc4db0ed46b787d29aa48e 802 Gene3D G3DSA:1.10.1060.10 400 480 0.0 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_1100 dae99c3eb8dc4db0ed46b787d29aa48e 802 Hamap MF_01137 Acetyl-CoA decarbonylase/synthase complex subunit alpha [cdhA]. 2 789 45.132 T 31-10-2018 IPR004460 Acetyl-CoA decarbonylase/synthase complex subunit alpha GO:0006084|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 AF_1100 dae99c3eb8dc4db0ed46b787d29aa48e 802 Pfam PF03063 Prismane/CO dehydrogenase family 66 123 6.4E-16 T 31-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 AF_1100 dae99c3eb8dc4db0ed46b787d29aa48e 802 SUPERFAMILY SSF46548 391 467 3.14E-12 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_1100 dae99c3eb8dc4db0ed46b787d29aa48e 802 Pfam PF03063 Prismane/CO dehydrogenase family 143 681 2.3E-81 T 31-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 AF_1100 dae99c3eb8dc4db0ed46b787d29aa48e 802 TIGRFAM TIGR00314 cdhA: CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit 3 789 0.0 T 31-10-2018 IPR004460 Acetyl-CoA decarbonylase/synthase complex subunit alpha GO:0006084|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 AF_1100 dae99c3eb8dc4db0ed46b787d29aa48e 802 Gene3D G3DSA:3.40.50.2030 36 765 0.0 T 31-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 AF_1100 dae99c3eb8dc4db0ed46b787d29aa48e 802 Gene3D G3DSA:3.40.50.2030 213 491 0.0 T 31-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 AF_1100 dae99c3eb8dc4db0ed46b787d29aa48e 802 Pfam PF13183 4Fe-4S dicluster domain 402 458 4.2E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1720 600d63bdca548e3cc13f969716320d96 552 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 379 527 1.4E-51 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AF_1720 600d63bdca548e3cc13f969716320d96 552 SUPERFAMILY SSF52518 356 549 2.64E-67 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold AF_1720 600d63bdca548e3cc13f969716320d96 552 Gene3D G3DSA:3.40.50.970 1 180 7.7E-72 T 31-10-2018 AF_1720 600d63bdca548e3cc13f969716320d96 552 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 190 325 3.1E-53 T 31-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AF_1720 600d63bdca548e3cc13f969716320d96 552 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 167 9.7E-58 T 31-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AF_1720 600d63bdca548e3cc13f969716320d96 552 Gene3D G3DSA:3.40.50.1220 184 348 9.6E-68 T 31-10-2018 AF_1720 600d63bdca548e3cc13f969716320d96 552 SUPERFAMILY SSF52518 1 179 1.58E-62 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold AF_1720 600d63bdca548e3cc13f969716320d96 552 ProSitePatterns PS00187 Thiamine pyrophosphate enzymes signature. 415 434 - T 31-10-2018 IPR000399 TPP-binding enzyme, conserved site GO:0000287|GO:0030976 AF_1720 600d63bdca548e3cc13f969716320d96 552 Gene3D G3DSA:3.40.50.970 349 552 1.3E-67 T 31-10-2018 AF_1720 600d63bdca548e3cc13f969716320d96 552 SUPERFAMILY SSF52467 183 350 2.52E-62 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AF_1720 600d63bdca548e3cc13f969716320d96 552 TIGRFAM TIGR00118 acolac_lg: acetolactate synthase, large subunit, biosynthetic type 1 551 2.5E-283 T 31-10-2018 IPR012846 Acetolactate synthase, large subunit, biosynthetic GO:0000287|GO:0003984|GO:0009082|GO:0030976|GO:0050660 KEGG: 00290+2.2.1.6|KEGG: 00650+2.2.1.6|KEGG: 00660+2.2.1.6|KEGG: 00770+2.2.1.6|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5938|MetaCyc: PWY-5939|MetaCyc: PWY-6389|MetaCyc: PWY-7111 AF_1907 499f60d03ee4e5c1b21ab3b36f7cb1ae 149 SMART SM01416 5 148 5.0E-89 T 31-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1907 499f60d03ee4e5c1b21ab3b36f7cb1ae 149 SUPERFAMILY SSF48140 4 145 1.2E-56 T 31-10-2018 IPR035970 Ribosomal protein L19/L19e superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1907 499f60d03ee4e5c1b21ab3b36f7cb1ae 149 Pfam PF01280 Ribosomal protein L19e 5 148 1.4E-58 T 31-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1907 499f60d03ee4e5c1b21ab3b36f7cb1ae 149 Gene3D G3DSA:1.10.1650.10 3 58 1.7E-25 T 31-10-2018 IPR015972 Ribosomal protein L19/L19e, domain 1 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1907 499f60d03ee4e5c1b21ab3b36f7cb1ae 149 Hamap MF_01475 50S ribosomal protein L19e [rpl19e]. 5 148 26.335 T 31-10-2018 IPR000196 Ribosomal protein L19/L19e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1907 499f60d03ee4e5c1b21ab3b36f7cb1ae 149 ProSitePatterns PS00526 Ribosomal protein L19e signature. 9 28 - T 31-10-2018 IPR023638 Ribosomal protein L19/L19e conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1907 499f60d03ee4e5c1b21ab3b36f7cb1ae 149 Gene3D G3DSA:1.10.1200.240 60 149 1.9E-27 T 31-10-2018 AF_1385 e2e7733a9b36137cbb06efaed7a9688b 149 Gene3D G3DSA:3.40.50.1010 4 122 1.6E-11 T 31-10-2018 AF_1385 e2e7733a9b36137cbb06efaed7a9688b 149 SUPERFAMILY SSF88723 4 121 8.41E-16 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_1385 e2e7733a9b36137cbb06efaed7a9688b 149 Pfam PF01850 PIN domain 5 120 2.9E-19 T 31-10-2018 IPR002716 PIN domain AF_1193 a2fe75c5d688abcdb783011b75edca25 193 TIGRFAM TIGR00024 SbcD_rel_arch: putative phosphoesterase 1 193 1.3E-73 T 31-10-2018 IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like AF_1193 a2fe75c5d688abcdb783011b75edca25 193 Pfam PF00149 Calcineurin-like phosphoesterase 14 118 6.3E-8 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AF_1193 a2fe75c5d688abcdb783011b75edca25 193 SUPERFAMILY SSF56300 14 127 2.59E-14 T 31-10-2018 AF_1193 a2fe75c5d688abcdb783011b75edca25 193 Gene3D G3DSA:3.60.21.10 11 178 4.7E-10 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like AF_2202 4f3e14925c6d94cd3686a7eb7ee42f88 228 PIRSF PIRSF038959 3 101 4.1E-12 T 31-10-2018 IPR026272 Immunity protein SdpI AF_2202 4f3e14925c6d94cd3686a7eb7ee42f88 228 PIRSF PIRSF038959 117 224 7.2E-7 T 31-10-2018 IPR026272 Immunity protein SdpI AF_2202 4f3e14925c6d94cd3686a7eb7ee42f88 228 Pfam PF07853 Protein of unknown function (DUF1648) 130 175 6.9E-15 T 31-10-2018 IPR012867 Domain of unknown function DUF1648 AF_2202 4f3e14925c6d94cd3686a7eb7ee42f88 228 Pfam PF13630 SdpI/YhfL protein family 25 91 9.6E-13 T 31-10-2018 IPR025962 SdpI/YhfL protein family AF_2226 8150c7ee0fc48976eb54ddebd3fb0a0c 352 Pfam PF14419 AF2226-like SPOUT RNA Methylase fused to THUMP 168 341 6.3E-79 T 31-10-2018 IPR025849 AF2226-like SPOUT RNA methylase fused to THUMP AF_2226 8150c7ee0fc48976eb54ddebd3fb0a0c 352 Gene3D G3DSA:3.30.2130.30 1 148 4.0E-22 T 31-10-2018 AF_2226 8150c7ee0fc48976eb54ddebd3fb0a0c 352 SUPERFAMILY SSF143437 9 145 4.71E-25 T 31-10-2018 AF_2226 8150c7ee0fc48976eb54ddebd3fb0a0c 352 SMART SM00981 58 147 1.6E-20 T 31-10-2018 IPR004114 THUMP domain GO:0003723 AF_2226 8150c7ee0fc48976eb54ddebd3fb0a0c 352 SUPERFAMILY SSF75217 186 335 1.92E-20 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases AF_2226 8150c7ee0fc48976eb54ddebd3fb0a0c 352 Pfam PF02926 THUMP domain 21 145 6.8E-30 T 31-10-2018 IPR004114 THUMP domain GO:0003723 AF_2119 2f07f41427189ae0c5bbf1a7787485e6 741 SUPERFAMILY SSF49373 205 260 1.14E-6 T 31-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments AF_2207 7ff6c7515ee5a6a7a214867c9d4dd201 297 PIRSF PIRSF006414 1 297 3.0E-149 T 31-10-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 AF_2207 7ff6c7515ee5a6a7a214867c9d4dd201 297 Hamap MF_00579 Formylmethanofuran--tetrahydromethanopterin formyltransferase [ftr]. 1 297 45.51 T 31-10-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 AF_2207 7ff6c7515ee5a6a7a214867c9d4dd201 297 TIGRFAM TIGR03119 one_C_fhcD: formylmethanofuran--tetrahydromethanopterin N-formyltransferase 8 296 1.2E-145 T 31-10-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 AF_2207 7ff6c7515ee5a6a7a214867c9d4dd201 297 Pfam PF01913 Formylmethanofuran-tetrahydromethanopterin formyltransferase 1 144 6.4E-61 T 31-10-2018 IPR022667 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, N-terminal GO:0006730|GO:0016740 AF_2207 7ff6c7515ee5a6a7a214867c9d4dd201 297 Gene3D G3DSA:3.30.70.520 3 296 3.5E-137 T 31-10-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily AF_2207 7ff6c7515ee5a6a7a214867c9d4dd201 297 SUPERFAMILY SSF55112 146 297 6.54E-62 T 31-10-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily AF_2207 7ff6c7515ee5a6a7a214867c9d4dd201 297 Pfam PF02741 FTR, proximal lobe 147 296 1.4E-65 T 31-10-2018 IPR002770 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, C-terminal GO:0006730|GO:0016740 AF_2207 7ff6c7515ee5a6a7a214867c9d4dd201 297 SUPERFAMILY SSF55112 1 145 1.39E-60 T 31-10-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily AF_2207 7ff6c7515ee5a6a7a214867c9d4dd201 297 Gene3D G3DSA:3.30.70.520 17 162 3.5E-137 T 31-10-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily AF_2366 e15d05b2662ef74e101275b0928c96bc 373 Gene3D G3DSA:3.90.1150.10 24 363 1.1E-106 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AF_2366 e15d05b2662ef74e101275b0928c96bc 373 Pfam PF00155 Aminotransferase class I and II 31 365 4.4E-64 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AF_2366 e15d05b2662ef74e101275b0928c96bc 373 Gene3D G3DSA:3.40.640.10 62 271 1.1E-106 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AF_2366 e15d05b2662ef74e101275b0928c96bc 373 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 221 234 - T 31-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AF_2366 e15d05b2662ef74e101275b0928c96bc 373 SUPERFAMILY SSF53383 4 368 1.45E-102 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AF_2136 ed42fa8e06383c0a357c8a27609dad9d 179 SMART SM00418 16 96 3.7E-23 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_2136 ed42fa8e06383c0a357c8a27609dad9d 179 Gene3D G3DSA:1.10.10.10 11 92 2.3E-20 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_2136 ed42fa8e06383c0a357c8a27609dad9d 179 SUPERFAMILY SSF46785 16 89 3.55E-24 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_2136 ed42fa8e06383c0a357c8a27609dad9d 179 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 65 80 1.5E-9 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_2136 ed42fa8e06383c0a357c8a27609dad9d 179 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 50 65 1.5E-9 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_2136 ed42fa8e06383c0a357c8a27609dad9d 179 PRINTS PR00778 Bacterial regulatory protein ArsR family signature 18 33 1.5E-9 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_2136 ed42fa8e06383c0a357c8a27609dad9d 179 Pfam PF01022 Bacterial regulatory protein, arsR family 23 69 3.0E-17 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_1751 ba1af87983f9afe1cd07e316b94bf522 408 PIRSF PIRSF006392 1 404 1.7E-160 T 31-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AF_1751 ba1af87983f9afe1cd07e316b94bf522 408 SUPERFAMILY SSF53649 2 403 6.35E-38 T 31-10-2018 IPR017850 Alkaline-phosphatase-like, core domain superfamily GO:0003824 AF_1751 ba1af87983f9afe1cd07e316b94bf522 408 TIGRFAM TIGR00306 apgM: phosphoglycerate mutase (2,3-diphosphoglycerate-independent), archaeal form 4 398 4.7E-180 T 31-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AF_1751 ba1af87983f9afe1cd07e316b94bf522 408 Pfam PF01676 Metalloenzyme superfamily 2 397 3.7E-50 T 31-10-2018 IPR006124 Metalloenzyme GO:0003824|GO:0046872 AF_1751 ba1af87983f9afe1cd07e316b94bf522 408 Hamap MF_01402_A 2,3-bisphosphoglycerate-independent phosphoglycerate mutase [apgM]. 1 399 48.292 T 31-10-2018 IPR023665 2,3-bisphosphoglycerate-independent phosphoglycerate mutase, prokaryotes GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AF_1751 ba1af87983f9afe1cd07e316b94bf522 408 Gene3D G3DSA:3.30.70.2130 75 229 6.8E-139 T 31-10-2018 AF_1751 ba1af87983f9afe1cd07e316b94bf522 408 Pfam PF10143 2,3-bisphosphoglycerate-independent phosphoglycerate mutase 34 207 8.8E-59 T 31-10-2018 IPR004456 2,3-bisphosphoglycerate-independent phosphoglycerate mutase GO:0003824|GO:0046537 KEGG: 00010+5.4.2.12|KEGG: 00260+5.4.2.12|KEGG: 00680+5.4.2.12|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AF_1751 ba1af87983f9afe1cd07e316b94bf522 408 Gene3D G3DSA:3.40.720.10 4 394 6.8E-139 T 31-10-2018 IPR017849 Alkaline phosphatase-like, alpha/beta/alpha GO:0003824 AF_0530 d8ae9065902ce6a363311d1225822ae3 507 SUPERFAMILY SSF56719 272 500 9.15E-88 T 31-10-2018 IPR013760 DNA topoisomerase, type IIA-like domain superfamily GO:0003918|GO:0005524 Reactome: R-HSA-4615885 AF_0530 d8ae9065902ce6a363311d1225822ae3 507 PRINTS PR00418 DNA topoisomerase II family signature 148 161 9.4E-46 T 31-10-2018 AF_0530 d8ae9065902ce6a363311d1225822ae3 507 PRINTS PR00418 DNA topoisomerase II family signature 296 310 9.4E-46 T 31-10-2018 AF_0530 d8ae9065902ce6a363311d1225822ae3 507 PRINTS PR00418 DNA topoisomerase II family signature 400 412 9.4E-46 T 31-10-2018 AF_0530 d8ae9065902ce6a363311d1225822ae3 507 PRINTS PR00418 DNA topoisomerase II family signature 380 397 9.4E-46 T 31-10-2018 AF_0530 d8ae9065902ce6a363311d1225822ae3 507 PRINTS PR00418 DNA topoisomerase II family signature 439 455 9.4E-46 T 31-10-2018 AF_0530 d8ae9065902ce6a363311d1225822ae3 507 PRINTS PR00418 DNA topoisomerase II family signature 362 378 9.4E-46 T 31-10-2018 AF_0530 d8ae9065902ce6a363311d1225822ae3 507 Gene3D G3DSA:3.30.230.10 102 275 2.0E-64 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AF_0530 d8ae9065902ce6a363311d1225822ae3 507 Pfam PF01751 Toprim domain 295 405 6.0E-18 T 31-10-2018 IPR006171 TOPRIM domain AF_0530 d8ae9065902ce6a363311d1225822ae3 507 PRINTS PR01159 DNA gyrase subunit B signature 346 355 4.7E-61 T 31-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AF_0530 d8ae9065902ce6a363311d1225822ae3 507 PRINTS PR01159 DNA gyrase subunit B signature 460 472 4.7E-61 T 31-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AF_0530 d8ae9065902ce6a363311d1225822ae3 507 PRINTS PR01159 DNA gyrase subunit B signature 237 251 4.7E-61 T 31-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AF_0530 d8ae9065902ce6a363311d1225822ae3 507 PRINTS PR01159 DNA gyrase subunit B signature 77 90 4.7E-61 T 31-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AF_0530 d8ae9065902ce6a363311d1225822ae3 507 PRINTS PR01159 DNA gyrase subunit B signature 122 140 4.7E-61 T 31-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AF_0530 d8ae9065902ce6a363311d1225822ae3 507 PRINTS PR01159 DNA gyrase subunit B signature 476 492 4.7E-61 T 31-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AF_0530 d8ae9065902ce6a363311d1225822ae3 507 PRINTS PR01159 DNA gyrase subunit B signature 62 77 4.7E-61 T 31-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AF_0530 d8ae9065902ce6a363311d1225822ae3 507 PRINTS PR01159 DNA gyrase subunit B signature 189 205 4.7E-61 T 31-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AF_0530 d8ae9065902ce6a363311d1225822ae3 507 PRINTS PR01159 DNA gyrase subunit B signature 251 271 4.7E-61 T 31-10-2018 IPR000565 DNA topoisomerase, type IIA, subunit B GO:0003677|GO:0003918|GO:0005524|GO:0006265 AF_0530 d8ae9065902ce6a363311d1225822ae3 507 Gene3D G3DSA:3.30.565.10 18 101 3.8E-23 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_0530 d8ae9065902ce6a363311d1225822ae3 507 SUPERFAMILY SSF54211 102 268 8.35E-50 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AF_0530 d8ae9065902ce6a363311d1225822ae3 507 Gene3D G3DSA:3.40.50.670 276 507 1.2E-107 T 31-10-2018 IPR013759 DNA topoisomerase, type IIA, subunit B, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AF_0530 d8ae9065902ce6a363311d1225822ae3 507 Pfam PF00204 DNA gyrase B 102 267 9.2E-54 T 31-10-2018 IPR013506 DNA topoisomerase, type IIA, subunit B, domain 2 GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AF_0530 d8ae9065902ce6a363311d1225822ae3 507 SUPERFAMILY SSF55874 35 100 4.01E-16 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_0530 d8ae9065902ce6a363311d1225822ae3 507 SMART SM00433 16 500 4.4E-211 T 31-10-2018 IPR001241 DNA topoisomerase, type IIA GO:0003677|GO:0003918|GO:0005524|GO:0006265 Reactome: R-HSA-4615885 AF_0530 d8ae9065902ce6a363311d1225822ae3 507 Pfam PF00986 DNA gyrase B subunit, carboxyl terminus 438 495 1.3E-29 T 31-10-2018 IPR002288 DNA gyrase B subunit, C-terminal GO:0003677|GO:0003918|GO:0005524|GO:0006265 AF_1676 ac7b13b391b7b2b2b3b2df2f12431212 245 Gene3D G3DSA:3.30.1600.10 29 162 4.2E-103 T 31-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily AF_1676 ac7b13b391b7b2b2b3b2df2f12431212 245 Gene3D G3DSA:3.40.50.1220 11 236 4.2E-103 T 31-10-2018 AF_1676 ac7b13b391b7b2b2b3b2df2f12431212 245 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 13 242 60.452 T 31-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 AF_1676 ac7b13b391b7b2b2b3b2df2f12431212 245 Pfam PF02146 Sir2 family 20 192 3.0E-61 T 31-10-2018 IPR003000 Sirtuin family GO:0070403 AF_1676 ac7b13b391b7b2b2b3b2df2f12431212 245 SUPERFAMILY SSF52467 3 240 8.39E-91 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AF_2101 518f799fc0e48ef5817b89e6dfe3fcf4 402 Pfam PF00107 Zinc-binding dehydrogenase 215 348 1.0E-28 T 31-10-2018 IPR013149 Alcohol dehydrogenase, C-terminal GO:0055114 AF_2101 518f799fc0e48ef5817b89e6dfe3fcf4 402 ProSitePatterns PS00059 Zinc-containing alcohol dehydrogenases signature. 87 101 - T 31-10-2018 IPR002328 Alcohol dehydrogenase, zinc-type, conserved site GO:0008270|GO:0016491|GO:0055114 Reactome: R-HSA-71384 AF_2101 518f799fc0e48ef5817b89e6dfe3fcf4 402 SUPERFAMILY SSF51735 181 344 3.54E-28 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_2101 518f799fc0e48ef5817b89e6dfe3fcf4 402 Gene3D G3DSA:3.90.180.10 43 381 2.4E-85 T 31-10-2018 AF_2101 518f799fc0e48ef5817b89e6dfe3fcf4 402 Gene3D G3DSA:3.40.50.720 192 337 2.4E-85 T 31-10-2018 AF_2101 518f799fc0e48ef5817b89e6dfe3fcf4 402 SUPERFAMILY SSF50129 35 213 3.98E-37 T 31-10-2018 IPR011032 GroES-like superfamily AF_2101 518f799fc0e48ef5817b89e6dfe3fcf4 402 Pfam PF08240 Alcohol dehydrogenase GroES-like domain 49 174 5.4E-25 T 31-10-2018 IPR013154 Alcohol dehydrogenase, N-terminal GO:0055114 AF_0315 a5ece8991dffc8790785a1795eb988f1 143 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 5 142 10.263 T 31-10-2018 IPR022907 VapC family GO:0004540 AF_0315 a5ece8991dffc8790785a1795eb988f1 143 SMART SM00670 3 134 8.9E-29 T 31-10-2018 IPR002716 PIN domain AF_0315 a5ece8991dffc8790785a1795eb988f1 143 Pfam PF01850 PIN domain 5 138 9.7E-29 T 31-10-2018 IPR002716 PIN domain AF_0315 a5ece8991dffc8790785a1795eb988f1 143 SUPERFAMILY SSF88723 1 137 1.04E-21 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_0315 a5ece8991dffc8790785a1795eb988f1 143 Gene3D G3DSA:3.40.50.1010 4 142 4.0E-15 T 31-10-2018 AF_0429 c71f6ddc9063380baaa5435aa5b4ab48 270 Pfam PF00891 O-methyltransferase 68 166 6.7E-17 T 31-10-2018 IPR001077 O-methyltransferase, family 2 GO:0008171 AF_0429 c71f6ddc9063380baaa5435aa5b4ab48 270 SUPERFAMILY SSF53335 39 259 2.71E-26 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_0429 c71f6ddc9063380baaa5435aa5b4ab48 270 Gene3D G3DSA:3.40.50.150 29 270 2.2E-24 T 31-10-2018 AF_1828 b45048f0cfa89bef6222a9898b4db6fb 124 Gene3D G3DSA:1.20.58.1610 2 119 2.1E-9 T 31-10-2018 IPR038430 NADH:ubiquinone oxidoreductase, subunit 3 superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1828 b45048f0cfa89bef6222a9898b4db6fb 124 Pfam PF00507 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 23 114 5.9E-8 T 31-10-2018 IPR000440 NADH:ubiquinone/plastoquinone oxidoreductase, chain 3 GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1206 46560342c5587e4bdaad4086c07fad42 315 Gene3D G3DSA:3.40.50.720 1 188 3.7E-61 T 31-10-2018 AF_1206 46560342c5587e4bdaad4086c07fad42 315 Gene3D G3DSA:1.10.1040.10 189 313 3.6E-30 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AF_1206 46560342c5587e4bdaad4086c07fad42 315 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 185 6.7E-60 T 31-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_1206 46560342c5587e4bdaad4086c07fad42 315 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 188 274 1.9E-17 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_1206 46560342c5587e4bdaad4086c07fad42 315 SUPERFAMILY SSF51735 4 184 3.07E-50 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1206 46560342c5587e4bdaad4086c07fad42 315 PIRSF PIRSF000105 2 313 5.1E-72 T 31-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 AF_1206 46560342c5587e4bdaad4086c07fad42 315 SUPERFAMILY SSF48179 188 257 9.35E-12 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_1203 c1915b84656af367ee2ee642800946e6 741 SMART SM00926 38 91 6.7E-13 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1203 c1915b84656af367ee2ee642800946e6 741 Pfam PF00384 Molybdopterin oxidoreductase 94 364 3.1E-43 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1203 c1915b84656af367ee2ee642800946e6 741 Pfam PF00384 Molybdopterin oxidoreductase 417 514 1.4E-17 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1203 c1915b84656af367ee2ee642800946e6 741 SUPERFAMILY SSF53706 40 616 7.33E-157 T 31-10-2018 AF_1203 c1915b84656af367ee2ee642800946e6 741 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 39 91 4.5E-13 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1203 c1915b84656af367ee2ee642800946e6 741 SUPERFAMILY SSF50692 568 736 2.28E-42 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AF_1203 c1915b84656af367ee2ee642800946e6 741 Gene3D G3DSA:2.40.40.20 585 737 8.4E-52 T 31-10-2018 AF_1203 c1915b84656af367ee2ee642800946e6 741 Gene3D G3DSA:3.40.50.740 96 544 1.9E-145 T 31-10-2018 AF_1203 c1915b84656af367ee2ee642800946e6 741 Pfam PF01568 Molydopterin dinucleotide binding domain 618 729 3.5E-30 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AF_1203 c1915b84656af367ee2ee642800946e6 741 Gene3D G3DSA:2.20.25.90 33 95 1.1E-17 T 31-10-2018 AF_1203 c1915b84656af367ee2ee642800946e6 741 Gene3D G3DSA:3.40.228.10 178 372 1.9E-145 T 31-10-2018 AF_1864 c26a275ee5a7ab30f894c85927755c46 104 TIGRFAM TIGR02579 cas_csx3: CRISPR-associated protein, Csx3 family 11 91 4.3E-43 T 31-10-2018 IPR013409 CRISPR-associated protein Csx3 AF_1864 c26a275ee5a7ab30f894c85927755c46 104 Pfam PF09620 CRISPR-associated protein (Cas_csx3) 15 90 4.3E-33 T 31-10-2018 IPR013409 CRISPR-associated protein Csx3 AF_0818 fe43a54fa29ce9f0c43fad556d708952 89 Gene3D G3DSA:3.30.70.100 1 89 5.9E-30 T 31-10-2018 AF_0818 fe43a54fa29ce9f0c43fad556d708952 89 ProSitePatterns PS00150 Acylphosphatase signature 1. 8 18 - T 31-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AF_0818 fe43a54fa29ce9f0c43fad556d708952 89 Pfam PF00708 Acylphosphatase 5 86 3.2E-27 T 31-10-2018 IPR001792 Acylphosphatase-like domain KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AF_0818 fe43a54fa29ce9f0c43fad556d708952 89 SUPERFAMILY SSF54975 1 88 1.09E-28 T 31-10-2018 IPR036046 Acylphosphatase-like domain superfamily KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AF_0818 fe43a54fa29ce9f0c43fad556d708952 89 ProSitePatterns PS00151 Acylphosphatase signature 2. 32 48 - T 31-10-2018 IPR017968 Acylphosphatase, conserved site KEGG: 00620+3.6.1.7|KEGG: 00627+3.6.1.7 AF_0012 5c3058ecf43847b6c17d2b89cea0815b 416 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 204 413 2.7E-17 T 31-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AF_0012 5c3058ecf43847b6c17d2b89cea0815b 416 Gene3D G3DSA:3.20.20.210 4 413 3.6E-45 T 31-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AF_0012 5c3058ecf43847b6c17d2b89cea0815b 416 SUPERFAMILY SSF51726 7 416 6.63E-41 T 31-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AF_1916 077de560915e53e5388ddf5e27e9ff4d 111 ProSitePatterns PS00056 Ribosomal protein S17 signature. 81 93 - T 31-10-2018 IPR019979 Ribosomal protein S17, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1916 077de560915e53e5388ddf5e27e9ff4d 111 Pfam PF00366 Ribosomal protein S17 35 102 3.1E-22 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1916 077de560915e53e5388ddf5e27e9ff4d 111 ProDom PD001295 RIBOSOMAL S17 30S RIBONUCLEOPROTEIN RRNA-BINDING RNA-BINDING 40S S11 S17P S11 33 100 7.0E-33 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1916 077de560915e53e5388ddf5e27e9ff4d 111 SUPERFAMILY SSF50249 29 108 8.14E-23 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_1916 077de560915e53e5388ddf5e27e9ff4d 111 TIGRFAM TIGR03630 uS17_arch: ribosomal protein uS17 4 103 4.8E-46 T 31-10-2018 IPR028333 Ribosomal protein S17, archaeal/eukaryotic Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1916 077de560915e53e5388ddf5e27e9ff4d 111 Hamap MF_01345_A 30S ribosomal protein S17 [rpsQ]. 2 105 33.387 T 31-10-2018 IPR019978 Ribosomal protein S17, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1916 077de560915e53e5388ddf5e27e9ff4d 111 PRINTS PR00973 Ribosomal protein S17 family signature 81 91 6.2E-12 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1916 077de560915e53e5388ddf5e27e9ff4d 111 PRINTS PR00973 Ribosomal protein S17 family signature 91 98 6.2E-12 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1916 077de560915e53e5388ddf5e27e9ff4d 111 PRINTS PR00973 Ribosomal protein S17 family signature 48 71 6.2E-12 T 31-10-2018 IPR000266 Ribosomal protein S17/S11 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1916 077de560915e53e5388ddf5e27e9ff4d 111 Gene3D G3DSA:2.40.50.1000 1 111 9.0E-37 T 31-10-2018 AF_0607 975f596f70381009d40fb4e2278ccc05 346 Gene3D G3DSA:3.40.50.2000 142 266 2.4E-25 T 31-10-2018 AF_0607 975f596f70381009d40fb4e2278ccc05 346 Pfam PF13692 Glycosyl transferases group 1 160 266 4.5E-19 T 31-10-2018 AF_0607 975f596f70381009d40fb4e2278ccc05 346 SUPERFAMILY SSF53756 39 333 3.93E-30 T 31-10-2018 AF_0607 975f596f70381009d40fb4e2278ccc05 346 Gene3D G3DSA:3.40.50.2000 7 141 2.4E-25 T 31-10-2018 AF_2237 ced54331347e61b52ee351df7807b0da 181 TIGRFAM TIGR00042 TIGR00042: non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family 1 176 1.3E-72 T 31-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 AF_2237 ced54331347e61b52ee351df7807b0da 181 SUPERFAMILY SSF52972 2 178 7.06E-60 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AF_2237 ced54331347e61b52ee351df7807b0da 181 Hamap MF_01405 dITP/XTP pyrophosphatase. 1 178 40.79 T 31-10-2018 IPR020922 dITP/XTP pyrophosphatase GO:0009143|GO:0017111 KEGG: 00230+3.6.1.66 AF_2237 ced54331347e61b52ee351df7807b0da 181 Gene3D G3DSA:3.90.950.10 1 181 1.7E-66 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AF_2237 ced54331347e61b52ee351df7807b0da 181 Pfam PF01725 Ham1 family 2 175 3.8E-51 T 31-10-2018 IPR002637 Ham1-like protein GO:0009143|GO:0047429 KEGG: 00230+3.6.1.66|Reactome: R-HSA-74259 AF_0066 0309802dcf455ef01c5b6b1f6409c494 62 SUPERFAMILY SSF89447 1 43 3.66E-8 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily AF_0066 0309802dcf455ef01c5b6b1f6409c494 62 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 1 31 4.3E-8 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AF_0066 0309802dcf455ef01c5b6b1f6409c494 62 Gene3D G3DSA:2.10.260.10 1 30 4.7E-7 T 31-10-2018 AF_0777 470a848242c80646a3eb08c5bc5c8c8b 88 Hamap MF_00216 Translation initiation factor 1A [eif1a]. 1 87 27.324 T 31-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 AF_0777 470a848242c80646a3eb08c5bc5c8c8b 88 SMART SM00652 5 87 9.1E-49 T 31-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 AF_0777 470a848242c80646a3eb08c5bc5c8c8b 88 Gene3D G3DSA:2.40.50.140 1 87 1.7E-35 T 31-10-2018 AF_0777 470a848242c80646a3eb08c5bc5c8c8b 88 ProDom PD005579 INITIATION FACTOR TRANSLATION 1A BIOSYNTHESIS EUKARYOTIC EIF-1A AIF-1A EIF-4C 1A 30 87 4.0E-27 T 31-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 AF_0777 470a848242c80646a3eb08c5bc5c8c8b 88 ProSitePatterns PS01262 Eukaryotic initiation factor 1A signature. 18 40 - T 31-10-2018 IPR018104 Translation initiation factor 1A (eIF-1A), conserved site GO:0003743|GO:0006413 AF_0777 470a848242c80646a3eb08c5bc5c8c8b 88 Pfam PF01176 Translation initiation factor 1A / IF-1 10 71 1.0E-25 T 31-10-2018 IPR006196 RNA-binding domain, S1, IF1 type GO:0003723|GO:0003743|GO:0006413 AF_0777 470a848242c80646a3eb08c5bc5c8c8b 88 TIGRFAM TIGR00523 eIF-1A: translation initiation factor eIF-1A 1 88 7.5E-48 T 31-10-2018 IPR001253 Translation initiation factor 1A (eIF-1A) GO:0003743|GO:0006413 AF_0777 470a848242c80646a3eb08c5bc5c8c8b 88 SUPERFAMILY SSF50249 2 86 4.0E-35 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_1774 3fd432ef9f8facd5917133074adc99e4 531 SUPERFAMILY SSF81301 433 498 6.54E-10 T 31-10-2018 AF_1774 3fd432ef9f8facd5917133074adc99e4 531 PIRSF PIRSF006060 2 433 1.2E-51 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AF_1774 3fd432ef9f8facd5917133074adc99e4 531 Gene3D G3DSA:1.20.1740.10 2 429 6.4E-91 T 31-10-2018 AF_1774 3fd432ef9f8facd5917133074adc99e4 531 Gene3D G3DSA:3.30.460.10 430 527 3.3E-8 T 31-10-2018 AF_1774 3fd432ef9f8facd5917133074adc99e4 531 Pfam PF13520 Amino acid permease 5 382 4.4E-31 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AF_1774 3fd432ef9f8facd5917133074adc99e4 531 Pfam PF01909 Nucleotidyltransferase domain 444 529 2.5E-12 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AF_1402 72eb81d3806de9aa649d7a00960b583d 328 Pfam PF01032 FecCD transport family 21 325 7.1E-86 T 31-10-2018 IPR000522 ABC transporter, permease protein, BtuC-like GO:0005215|GO:0016020 AF_1402 72eb81d3806de9aa649d7a00960b583d 328 SUPERFAMILY SSF81345 10 326 7.19E-73 T 31-10-2018 IPR037294 ABC transporter, BtuC-like AF_1402 72eb81d3806de9aa649d7a00960b583d 328 Gene3D G3DSA:1.10.3470.10 6 328 4.5E-92 T 31-10-2018 IPR037294 ABC transporter, BtuC-like AF_1285 809c7dcffa5ca9cb7e2de8fc51f40116 352 ProSitePatterns PS00674 AAA-protein family signature. 239 258 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AF_1285 809c7dcffa5ca9cb7e2de8fc51f40116 352 SUPERFAMILY SSF52540 96 338 9.81E-58 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1285 809c7dcffa5ca9cb7e2de8fc51f40116 352 SMART SM00382 134 269 2.1E-18 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1285 809c7dcffa5ca9cb7e2de8fc51f40116 352 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 138 266 4.0E-37 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AF_1285 809c7dcffa5ca9cb7e2de8fc51f40116 352 Gene3D G3DSA:1.10.8.60 269 349 8.6E-11 T 31-10-2018 AF_1285 809c7dcffa5ca9cb7e2de8fc51f40116 352 Gene3D G3DSA:3.40.50.300 93 268 3.1E-50 T 31-10-2018 AF_1018 041add887d1b7f7c632ab9030c3d84a1 228 SUPERFAMILY SSF52540 3 226 1.33E-78 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1018 041add887d1b7f7c632ab9030c3d84a1 228 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_1018 041add887d1b7f7c632ab9030c3d84a1 228 Pfam PF00005 ABC transporter 23 171 9.6E-38 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_1018 041add887d1b7f7c632ab9030c3d84a1 228 Gene3D G3DSA:3.40.50.300 1 227 5.7E-76 T 31-10-2018 AF_1018 041add887d1b7f7c632ab9030c3d84a1 228 SMART SM00382 32 220 3.6E-19 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0493 4a7804ed0070e3e73202bb7565208eb6 258 SUPERFAMILY SSF54211 11 180 1.32E-45 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AF_0493 4a7804ed0070e3e73202bb7565208eb6 258 Pfam PF03725 3' exoribonuclease family, domain 2 158 225 1.6E-15 T 31-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AF_0493 4a7804ed0070e3e73202bb7565208eb6 258 Pfam PF01138 3' exoribonuclease family, domain 1 25 154 1.6E-35 T 31-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AF_0493 4a7804ed0070e3e73202bb7565208eb6 258 TIGRFAM TIGR02065 ECX1: exosome complex exonuclease 1 11 241 6.2E-106 T 31-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 AF_0493 4a7804ed0070e3e73202bb7565208eb6 258 SUPERFAMILY SSF55666 154 244 1.44E-23 T 31-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AF_0493 4a7804ed0070e3e73202bb7565208eb6 258 Hamap MF_00591 Exosome complex component Rrp41 [rrp41]. 7 245 56.919 T 31-10-2018 IPR011807 Exosome complex component Rrp41 GO:0000178|GO:0006401|GO:0016896 AF_0493 4a7804ed0070e3e73202bb7565208eb6 258 Gene3D G3DSA:3.30.230.70 24 258 9.6E-82 T 31-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AF_2212 9e3a814a85c781c8add99916b2b39b9d 61 Pfam PF01954 Protein of unknown function DUF104 1 34 1.9E-17 T 31-10-2018 IPR008203 Uncharacterised protein family UPF0165 AF_2212 9e3a814a85c781c8add99916b2b39b9d 61 Gene3D G3DSA:4.10.1150.10 1 61 1.1E-30 T 31-10-2018 IPR024069 AF2212-like domain superfamily AF_2212 9e3a814a85c781c8add99916b2b39b9d 61 SUPERFAMILY SSF141694 1 59 2.04E-17 T 31-10-2018 AF_1766 0ae6591a41193b45f6803f85da60d6e3 595 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 282 401 2.1E-13 T 31-10-2018 IPR000014 PAS domain AF_1766 0ae6591a41193b45f6803f85da60d6e3 595 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 405 520 1.1E-18 T 31-10-2018 IPR000014 PAS domain AF_1766 0ae6591a41193b45f6803f85da60d6e3 595 SUPERFAMILY SSF55785 391 516 9.77E-25 T 31-10-2018 IPR035965 PAS domain superfamily AF_1766 0ae6591a41193b45f6803f85da60d6e3 595 SUPERFAMILY SSF53850 24 240 4.35E-34 T 31-10-2018 AF_1766 0ae6591a41193b45f6803f85da60d6e3 595 SMART SM00062 23 241 5.8E-46 T 31-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AF_1766 0ae6591a41193b45f6803f85da60d6e3 595 Gene3D G3DSA:3.30.450.20 406 520 4.2E-21 T 31-10-2018 AF_1766 0ae6591a41193b45f6803f85da60d6e3 595 Pfam PF08448 PAS fold 292 396 1.0E-8 T 31-10-2018 IPR013656 PAS fold-4 AF_1766 0ae6591a41193b45f6803f85da60d6e3 595 Pfam PF08448 PAS fold 412 519 1.6E-13 T 31-10-2018 IPR013656 PAS fold-4 AF_1766 0ae6591a41193b45f6803f85da60d6e3 595 Gene3D G3DSA:3.30.450.20 275 405 4.9E-23 T 31-10-2018 AF_1766 0ae6591a41193b45f6803f85da60d6e3 595 SUPERFAMILY SSF55785 277 392 1.47E-16 T 31-10-2018 IPR035965 PAS domain superfamily AF_1766 0ae6591a41193b45f6803f85da60d6e3 595 Gene3D G3DSA:3.40.190.10 30 226 4.9E-29 T 31-10-2018 AF_1766 0ae6591a41193b45f6803f85da60d6e3 595 SMART SM00388 527 586 1.9E-5 T 31-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AF_1766 0ae6591a41193b45f6803f85da60d6e3 595 Pfam PF00497 Bacterial extracellular solute-binding proteins, family 3 24 239 1.5E-27 T 31-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AF_1766 0ae6591a41193b45f6803f85da60d6e3 595 Gene3D G3DSA:3.40.190.10 106 199 4.9E-29 T 31-10-2018 AF_1766 0ae6591a41193b45f6803f85da60d6e3 595 SMART SM00091 286 348 5.5E-4 T 31-10-2018 IPR000014 PAS domain AF_1766 0ae6591a41193b45f6803f85da60d6e3 595 SMART SM00091 406 470 4.9E-6 T 31-10-2018 IPR000014 PAS domain AF_1766 0ae6591a41193b45f6803f85da60d6e3 595 SMART SM00086 477 518 4.2E-4 T 31-10-2018 IPR001610 PAC motif AF_2014 784962c82d41ee14dc725e0f891a7516 401 SUPERFAMILY SSF103473 9 400 1.06E-66 T 31-10-2018 IPR036259 MFS transporter superfamily AF_2014 784962c82d41ee14dc725e0f891a7516 401 Gene3D G3DSA:1.20.1250.20 9 401 1.5E-63 T 31-10-2018 AF_2014 784962c82d41ee14dc725e0f891a7516 401 Pfam PF07690 Major Facilitator Superfamily 27 354 1.0E-39 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AF_1212 7dfe0caf9d0cd0c46e1432956103c32d 352 Gene3D G3DSA:3.40.1390.20 204 338 3.6E-50 T 31-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily AF_1212 7dfe0caf9d0cd0c46e1432956103c32d 352 Pfam PF13500 AAA domain 4 204 8.9E-17 T 31-10-2018 AF_1212 7dfe0caf9d0cd0c46e1432956103c32d 352 SUPERFAMILY SSF75138 207 322 1.27E-30 T 31-10-2018 IPR028979 HPr(Ser) kinase/phosphorylase-like, N-terminal domain superfamily AF_1212 7dfe0caf9d0cd0c46e1432956103c32d 352 Pfam PF07085 DRTGG domain 211 316 6.4E-26 T 31-10-2018 IPR010766 DRTGG KEGG: 00430+2.3.1.8|KEGG: 00620+2.3.1.8|KEGG: 00640+2.3.1.8|KEGG: 00680+2.3.1.8|KEGG: 00720+2.3.1.8|MetaCyc: PWY-1281|MetaCyc: PWY-5482|MetaCyc: PWY-5485|MetaCyc: PWY-5497|MetaCyc: PWY-6637 AF_1212 7dfe0caf9d0cd0c46e1432956103c32d 352 SUPERFAMILY SSF52540 2 210 1.06E-21 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1212 7dfe0caf9d0cd0c46e1432956103c32d 352 Gene3D G3DSA:3.40.50.300 3 203 2.1E-18 T 31-10-2018 AF_1132 5d3260b437b66a17d702d2d3719af16a 366 SMART SM01193 1 87 3.9E-13 T 31-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AF_1132 5d3260b437b66a17d702d2d3719af16a 366 Gene3D G3DSA:3.20.20.120 82 364 4.4E-99 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AF_1132 5d3260b437b66a17d702d2d3719af16a 366 SUPERFAMILY SSF51604 94 361 3.01E-95 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AF_1132 5d3260b437b66a17d702d2d3719af16a 366 SUPERFAMILY SSF54826 1 91 1.35E-23 T 31-10-2018 AF_1132 5d3260b437b66a17d702d2d3719af16a 366 Hamap MF_00318 Enolase [eno]. 1 358 32.702 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AF_1132 5d3260b437b66a17d702d2d3719af16a 366 Pfam PF03952 Enolase, N-terminal domain 2 87 6.7E-20 T 31-10-2018 IPR020811 Enolase, N-terminal KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AF_1132 5d3260b437b66a17d702d2d3719af16a 366 PRINTS PR00148 Enolase signature 259 270 1.2E-33 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AF_1132 5d3260b437b66a17d702d2d3719af16a 366 PRINTS PR00148 Enolase signature 2 16 1.2E-33 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AF_1132 5d3260b437b66a17d702d2d3719af16a 366 PRINTS PR00148 Enolase signature 114 127 1.2E-33 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AF_1132 5d3260b437b66a17d702d2d3719af16a 366 PRINTS PR00148 Enolase signature 311 328 1.2E-33 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AF_1132 5d3260b437b66a17d702d2d3719af16a 366 PRINTS PR00148 Enolase signature 60 76 1.2E-33 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AF_1132 5d3260b437b66a17d702d2d3719af16a 366 PRINTS PR00148 Enolase signature 282 296 1.2E-33 T 31-10-2018 IPR000941 Enolase GO:0000015|GO:0000287|GO:0004634|GO:0006096 KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AF_1132 5d3260b437b66a17d702d2d3719af16a 366 ProSitePatterns PS00164 Enolase signature. 282 295 - T 31-10-2018 IPR020809 Enolase, conserved site KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218|Reactome: R-HSA-70171|Reactome: R-HSA-70263 AF_1132 5d3260b437b66a17d702d2d3719af16a 366 SMART SM01192 92 362 4.3E-135 T 31-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AF_1132 5d3260b437b66a17d702d2d3719af16a 366 Pfam PF00113 Enolase, C-terminal TIM barrel domain 94 358 1.3E-73 T 31-10-2018 IPR020810 Enolase, C-terminal TIM barrel domain KEGG: 00010+4.2.1.11|KEGG: 00680+4.2.1.11|MetaCyc: PWY-1042|MetaCyc: PWY-1622|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7124|MetaCyc: PWY-7218 AF_1132 5d3260b437b66a17d702d2d3719af16a 366 Gene3D G3DSA:3.30.390.10 1 80 1.1E-17 T 31-10-2018 IPR029017 Enolase-like, N-terminal AF_0676 69ed690df37776271be520599a3f6765 217 Gene3D G3DSA:3.40.50.300 1 217 9.9E-94 T 31-10-2018 AF_0676 69ed690df37776271be520599a3f6765 217 PRINTS PR00094 Adenylate kinase signature 32 46 1.7E-37 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AF_0676 69ed690df37776271be520599a3f6765 217 PRINTS PR00094 Adenylate kinase signature 160 175 1.7E-37 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AF_0676 69ed690df37776271be520599a3f6765 217 PRINTS PR00094 Adenylate kinase signature 4 17 1.7E-37 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AF_0676 69ed690df37776271be520599a3f6765 217 PRINTS PR00094 Adenylate kinase signature 177 191 1.7E-37 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AF_0676 69ed690df37776271be520599a3f6765 217 PRINTS PR00094 Adenylate kinase signature 81 97 1.7E-37 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AF_0676 69ed690df37776271be520599a3f6765 217 Hamap MF_00235 Adenylate kinase [adk]. 1 213 56.357 T 31-10-2018 IPR000850 Adenylate kinase/UMP-CMP kinase GO:0005524|GO:0006139|GO:0019205 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AF_0676 69ed690df37776271be520599a3f6765 217 Pfam PF00406 Adenylate kinase 6 190 9.1E-64 T 31-10-2018 AF_0676 69ed690df37776271be520599a3f6765 217 Pfam PF05191 Adenylate kinase, active site lid 127 162 1.7E-17 T 31-10-2018 IPR007862 Adenylate kinase, active site lid domain GO:0004017 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 AF_0676 69ed690df37776271be520599a3f6765 217 SUPERFAMILY SSF52540 1 214 7.54E-53 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0676 69ed690df37776271be520599a3f6765 217 TIGRFAM TIGR01351 adk: adenylate kinase 2 212 1.1E-90 T 31-10-2018 IPR006259 Adenylate kinase subfamily GO:0004017|GO:0005524|GO:0016776 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219 AF_0676 69ed690df37776271be520599a3f6765 217 ProSitePatterns PS00113 Adenylate kinase signature. 81 92 - T 31-10-2018 IPR033690 Adenylate kinase, conserved site KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AF_1310 94981eb6830806c7476b4300ab22c3a9 299 SUPERFAMILY SSF46689 4 109 8.51E-14 T 31-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AF_1310 94981eb6830806c7476b4300ab22c3a9 299 SUPERFAMILY SSF53098 125 270 1.01E-28 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily AF_1310 94981eb6830806c7476b4300ab22c3a9 299 Pfam PF13518 Helix-turn-helix domain 12 58 2.2E-8 T 31-10-2018 AF_1310 94981eb6830806c7476b4300ab22c3a9 299 Gene3D G3DSA:3.30.420.10 124 290 8.5E-23 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AF_1310 94981eb6830806c7476b4300ab22c3a9 299 Pfam PF00665 Integrase core domain 129 245 1.5E-25 T 31-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AF_1761 475da9cfc9e306276399580518bf9d88 165 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 5 159 1.1E-66 T 31-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 AF_1761 475da9cfc9e306276399580518bf9d88 165 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 3 162 40.624 T 31-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 AF_1761 475da9cfc9e306276399580518bf9d88 165 SUPERFAMILY SSF52016 3 161 1.86E-52 T 31-10-2018 AF_1761 475da9cfc9e306276399580518bf9d88 165 Gene3D G3DSA:3.20.19.10 1 163 9.8E-58 T 31-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 AF_1761 475da9cfc9e306276399580518bf9d88 165 Pfam PF00694 Aconitase C-terminal domain 42 101 1.4E-20 T 31-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 AF_1104 f8adbf5f9072fbd2f416eca8f92cb77a 288 PIRSF PIRSF006593 1 288 3.3E-100 T 31-10-2018 IPR014444 Uncharacterised conserved protein UCP006593 AF_1104 f8adbf5f9072fbd2f416eca8f92cb77a 288 Gene3D G3DSA:1.10.285.20 69 139 2.3E-29 T 31-10-2018 AF_1104 f8adbf5f9072fbd2f416eca8f92cb77a 288 SUPERFAMILY SSF111321 7 285 1.44E-83 T 31-10-2018 IPR036075 AF1104-like superfamily AF_1104 f8adbf5f9072fbd2f416eca8f92cb77a 288 Gene3D G3DSA:1.10.8.380 7 68 6.2E-33 T 31-10-2018 AF_1104 f8adbf5f9072fbd2f416eca8f92cb77a 288 Pfam PF01937 Protein of unknown function DUF89 6 282 2.1E-57 T 31-10-2018 IPR002791 Domain of unknown function DUF89 AF_1104 f8adbf5f9072fbd2f416eca8f92cb77a 288 Gene3D G3DSA:3.40.50.10880 140 288 2.5E-57 T 31-10-2018 AF_0221 a01f4adc163ffe786a434c4f072183ce 224 SMART SM00382 28 213 9.0E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0221 a01f4adc163ffe786a434c4f072183ce 224 SUPERFAMILY SSF52540 2 215 3.26E-57 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0221 a01f4adc163ffe786a434c4f072183ce 224 Gene3D G3DSA:3.40.50.300 2 224 1.4E-56 T 31-10-2018 AF_0221 a01f4adc163ffe786a434c4f072183ce 224 Pfam PF00005 ABC transporter 19 155 2.5E-31 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0221 a01f4adc163ffe786a434c4f072183ce 224 ProSitePatterns PS00211 ABC transporters family signature. 128 142 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_0918 c9bc9c4f0d83e7fabdf9c23b25207054 283 SUPERFAMILY SSF102114 40 208 3.4E-29 T 31-10-2018 AF_0918 c9bc9c4f0d83e7fabdf9c23b25207054 283 ProSitePatterns PS01305 moaA / nifB / pqqE family signature. 42 53 - T 31-10-2018 IPR000385 MoaA/nifB/pqqE, iron-sulphur binding, conserved site GO:0003824|GO:0046872|GO:0051539 KEGG: 00790+4.1.99.22|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AF_0918 c9bc9c4f0d83e7fabdf9c23b25207054 283 Gene3D G3DSA:3.20.20.70 27 255 2.9E-32 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0918 c9bc9c4f0d83e7fabdf9c23b25207054 283 SMART SM00729 36 228 0.0011 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AF_0918 c9bc9c4f0d83e7fabdf9c23b25207054 283 Pfam PF04055 Radical SAM superfamily 41 188 4.5E-14 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_0023 ae16aabf8e066b1f3d94410a30f43b19 592 Gene3D G3DSA:3.60.9.10 1 208 1.6E-81 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily AF_0023 ae16aabf8e066b1f3d94410a30f43b19 592 SMART SM00790 4 205 4.2E-118 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 AF_0023 ae16aabf8e066b1f3d94410a30f43b19 592 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 224 588 1.8E-104 T 31-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 AF_0023 ae16aabf8e066b1f3d94410a30f43b19 592 SUPERFAMILY SSF48310 212 591 1.83E-110 T 31-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 AF_0023 ae16aabf8e066b1f3d94410a30f43b19 592 Gene3D G3DSA:1.10.569.10 240 412 2.4E-107 T 31-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 AF_0023 ae16aabf8e066b1f3d94410a30f43b19 592 Gene3D G3DSA:1.10.599.10 238 588 2.4E-107 T 31-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 AF_0023 ae16aabf8e066b1f3d94410a30f43b19 592 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 6 203 1.9E-75 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 AF_0023 ae16aabf8e066b1f3d94410a30f43b19 592 SUPERFAMILY SSF56228 1 205 4.97E-73 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily AF_0588 32c8fe4a118292df19b76aef9d92aeaf 481 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 4 336 2.1E-110 T 31-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AF_0588 32c8fe4a118292df19b76aef9d92aeaf 481 Hamap MF_01634 tRNA-guanine(15) transglycosylase [tgtA]. 4 481 45.252 T 31-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 AF_0588 32c8fe4a118292df19b76aef9d92aeaf 481 SUPERFAMILY SSF51713 2 353 1.96E-105 T 31-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AF_0588 32c8fe4a118292df19b76aef9d92aeaf 481 TIGRFAM TIGR00432 arcsn_tRNA_tgt: tRNA-guanine(15) transglycosylase 4 481 3.0E-258 T 31-10-2018 IPR004804 tRNA-guanine(15) transglycosylase GO:0006400|GO:0016763 MetaCyc: PWY-6711|MetaCyc: PWY-7923 AF_0588 32c8fe4a118292df19b76aef9d92aeaf 481 Pfam PF01702 Queuine tRNA-ribosyltransferase 105 328 1.5E-38 T 31-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AF_0588 32c8fe4a118292df19b76aef9d92aeaf 481 Gene3D G3DSA:3.20.20.105 1 354 5.3E-105 T 31-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AF_0588 32c8fe4a118292df19b76aef9d92aeaf 481 SUPERFAMILY SSF88802 358 435 4.25E-10 T 31-10-2018 AF_1935 b297b5c5ecad8de7cdfb877ac26a98dc 316 Pfam PF02289 Cyclohydrolase (MCH) 3 310 1.5E-137 T 31-10-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 AF_1935 b297b5c5ecad8de7cdfb877ac26a98dc 316 Hamap MF_00486 Methenyltetrahydromethanopterin cyclohydrolase [mch]. 1 314 156.477 T 31-10-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 AF_1935 b297b5c5ecad8de7cdfb877ac26a98dc 316 Gene3D G3DSA:3.10.340.11 2 169 2.1E-141 T 31-10-2018 AF_1935 b297b5c5ecad8de7cdfb877ac26a98dc 316 TIGRFAM TIGR03120 one_C_mch: methenyltetrahydromethanopterin cyclohydrolase 3 311 4.0E-149 T 31-10-2018 IPR003209 Methenyltetrahydromethanopterin cyclohydrolase GO:0006730|GO:0018759 KEGG: 00680+3.5.4.27|MetaCyc: PWY-1723|MetaCyc: PWY-7784 AF_1935 b297b5c5ecad8de7cdfb877ac26a98dc 316 Gene3D G3DSA:3.30.1030.10 45 306 2.1E-141 T 31-10-2018 AF_1935 b297b5c5ecad8de7cdfb877ac26a98dc 316 SUPERFAMILY SSF56199 1 311 6.15E-132 T 31-10-2018 AF_1952 8ed4cecdd76b5554b4d78053106e148f 238 SMART SM00730 15 238 2.0E-55 T 31-10-2018 IPR006639 Presenilin/signal peptide peptidase GO:0004190|GO:0016021 AF_1952 8ed4cecdd76b5554b4d78053106e148f 238 Pfam PF06550 Signal-peptide peptidase, presenilin aspartyl protease 5 237 9.6E-48 T 31-10-2018 IPR010545 Signal-peptide peptidase, presenilin aspartyl protease AF_0452 4af88b0c6c2df01a22beab156898d28d 443 Pfam PF06745 KaiC 241 431 2.8E-20 T 31-10-2018 IPR014774 KaiC-like domain AF_0452 4af88b0c6c2df01a22beab156898d28d 443 Pfam PF06745 KaiC 4 225 6.3E-67 T 31-10-2018 IPR014774 KaiC-like domain AF_0452 4af88b0c6c2df01a22beab156898d28d 443 Gene3D G3DSA:3.40.50.300 1 229 4.2E-51 T 31-10-2018 AF_0452 4af88b0c6c2df01a22beab156898d28d 443 SMART SM00382 20 185 0.0088 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0452 4af88b0c6c2df01a22beab156898d28d 443 SMART SM00382 257 408 0.0087 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0452 4af88b0c6c2df01a22beab156898d28d 443 SUPERFAMILY SSF52540 238 431 7.89E-28 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0452 4af88b0c6c2df01a22beab156898d28d 443 PIRSF PIRSF039117 1 442 5.3E-129 T 31-10-2018 IPR030665 Circadian clock protein kinase KaiC KEGG: 04150+2.7.11.1|KEGG: 04151+2.7.11.1|KEGG: 04714+2.7.11.1|KEGG: 04926+2.7.11.1|KEGG: 05163+2.7.11.1|KEGG: 05165+2.7.11.1|KEGG: 05170+2.7.11.1 AF_0452 4af88b0c6c2df01a22beab156898d28d 443 Gene3D G3DSA:3.40.50.300 230 441 4.2E-36 T 31-10-2018 AF_0452 4af88b0c6c2df01a22beab156898d28d 443 PRINTS PR01874 DNA repair protein radA signature 249 277 8.5E-7 T 31-10-2018 AF_0452 4af88b0c6c2df01a22beab156898d28d 443 PRINTS PR01874 DNA repair protein radA signature 291 308 8.5E-7 T 31-10-2018 AF_0452 4af88b0c6c2df01a22beab156898d28d 443 SUPERFAMILY SSF52540 2 217 8.57E-37 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 Pfam PF00015 Methyl-accepting chemotaxis protein (MCP) signalling domain 604 760 1.7E-40 T 31-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 Gene3D G3DSA:1.10.287.950 487 809 8.7E-66 T 31-10-2018 AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 SMART SM00304 452 504 6.9E-10 T 31-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 SUPERFAMILY SSF58104 472 798 5.93E-64 T 31-10-2018 AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 308 446 7.9E-14 T 31-10-2018 IPR000014 PAS domain AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 75 183 6.0E-9 T 31-10-2018 IPR000014 PAS domain AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 192 311 2.6E-12 T 31-10-2018 IPR000014 PAS domain AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 SUPERFAMILY SSF55785 301 432 7.68E-16 T 31-10-2018 IPR035965 PAS domain superfamily AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 SMART SM00086 398 440 0.012 T 31-10-2018 IPR001610 PAC motif AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 SMART SM00086 136 177 5.8 T 31-10-2018 IPR001610 PAC motif AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 SMART SM00086 264 305 0.01 T 31-10-2018 IPR001610 PAC motif AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 SUPERFAMILY SSF55785 174 303 2.62E-20 T 31-10-2018 IPR035965 PAS domain superfamily AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 Gene3D G3DSA:3.30.450.20 186 312 6.2E-17 T 31-10-2018 AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 SMART SM00283 533 794 6.7E-81 T 31-10-2018 IPR004089 Methyl-accepting chemotaxis protein (MCP) signalling domain GO:0007165|GO:0016020 AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 Pfam PF00989 PAS fold 311 431 1.2E-13 T 31-10-2018 IPR013767 PAS fold GO:0006355 AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 Gene3D G3DSA:3.30.450.20 49 184 9.7E-17 T 31-10-2018 AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 SUPERFAMILY SSF55785 77 183 1.64E-13 T 31-10-2018 IPR035965 PAS domain superfamily AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 Gene3D G3DSA:3.30.450.20 313 452 2.6E-22 T 31-10-2018 AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 Pfam PF13426 PAS domain 202 304 1.4E-11 T 31-10-2018 IPR000014 PAS domain AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 Pfam PF13426 PAS domain 76 176 1.1E-8 T 31-10-2018 IPR000014 PAS domain AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 SMART SM00091 310 377 1.7E-5 T 31-10-2018 IPR000014 PAS domain AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 SMART SM00091 62 129 11.0 T 31-10-2018 IPR000014 PAS domain AF_1045 06c0606469db2a0d0496e0cd32fa9804 834 SMART SM00091 189 258 0.8 T 31-10-2018 IPR000014 PAS domain AF_1291 5e347e705933bee850309cf6776cc23d 392 PIRSF PIRSF000429 1 387 1.8E-59 T 31-10-2018 IPR002155 Thiolase GO:0016747 AF_1291 5e347e705933bee850309cf6776cc23d 392 Pfam PF02803 Thiolase, C-terminal domain 266 359 1.0E-10 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 AF_1291 5e347e705933bee850309cf6776cc23d 392 SUPERFAMILY SSF53901 4 356 1.7E-39 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_1291 5e347e705933bee850309cf6776cc23d 392 Pfam PF00108 Thiolase, N-terminal domain 1 226 4.3E-16 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AF_1291 5e347e705933bee850309cf6776cc23d 392 Gene3D G3DSA:3.40.47.10 1 390 1.0E-111 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0018 3a4f823dea099e1a5c18aae7d0b6e1bb 391 ProSitePatterns PS00737 Thiolases signature 2. 319 335 - T 31-10-2018 IPR020613 Thiolase, conserved site GO:0016747 AF_0018 3a4f823dea099e1a5c18aae7d0b6e1bb 391 PIRSF PIRSF000429 1 371 4.5E-53 T 31-10-2018 IPR002155 Thiolase GO:0016747 AF_0018 3a4f823dea099e1a5c18aae7d0b6e1bb 391 Gene3D G3DSA:3.40.47.10 1 382 4.1E-113 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0018 3a4f823dea099e1a5c18aae7d0b6e1bb 391 SUPERFAMILY SSF53901 228 379 3.45E-27 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0018 3a4f823dea099e1a5c18aae7d0b6e1bb 391 Pfam PF02803 Thiolase, C-terminal domain 260 347 1.5E-9 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 AF_0018 3a4f823dea099e1a5c18aae7d0b6e1bb 391 SUPERFAMILY SSF53901 1 224 1.01E-38 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0018 3a4f823dea099e1a5c18aae7d0b6e1bb 391 Pfam PF00108 Thiolase, N-terminal domain 1 219 1.6E-19 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AF_0868 e963cd798a8726802f16941470094712 447 Gene3D G3DSA:3.40.462.40 261 402 7.2E-21 T 31-10-2018 AF_0868 e963cd798a8726802f16941470094712 447 SUPERFAMILY SSF55103 227 447 1.21E-22 T 31-10-2018 IPR016164 FAD-linked oxidase-like, C-terminal GO:0003824|GO:0050660 AF_0868 e963cd798a8726802f16941470094712 447 Gene3D G3DSA:3.30.465.40 22 237 7.0E-64 T 31-10-2018 AF_0868 e963cd798a8726802f16941470094712 447 SUPERFAMILY SSF56176 18 222 4.67E-53 T 31-10-2018 IPR036318 FAD-binding, type PCMH-like superfamily GO:0050660 AF_0868 e963cd798a8726802f16941470094712 447 Pfam PF01565 FAD binding domain 49 185 1.8E-39 T 31-10-2018 IPR006094 FAD linked oxidase, N-terminal GO:0016491|GO:0050660|GO:0055114 AF_0868 e963cd798a8726802f16941470094712 447 Pfam PF02913 FAD linked oxidases, C-terminal domain 222 444 1.0E-21 T 31-10-2018 IPR004113 FAD-linked oxidase, C-terminal GO:0003824|GO:0050660 AF_0663 8f5e0a74fd527f3fcf93532ea8c9f89f 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 5 24 4.6E-7 T 31-10-2018 AF_0663 8f5e0a74fd527f3fcf93532ea8c9f89f 404 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 339 355 4.6E-7 T 31-10-2018 AF_0663 8f5e0a74fd527f3fcf93532ea8c9f89f 404 Pfam PF12831 FAD dependent oxidoreductase 5 42 1.3E-9 T 31-10-2018 IPR039649 Digeranylgeranylglycerophospholipid reductase, N-terminal AF_0663 8f5e0a74fd527f3fcf93532ea8c9f89f 404 Gene3D G3DSA:3.50.50.60 260 403 2.0E-5 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0663 8f5e0a74fd527f3fcf93532ea8c9f89f 404 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 104 115 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0663 8f5e0a74fd527f3fcf93532ea8c9f89f 404 Gene3D G3DSA:3.40.50.720 2 101 2.3E-11 T 31-10-2018 AF_0663 8f5e0a74fd527f3fcf93532ea8c9f89f 404 SUPERFAMILY SSF51905 5 398 5.44E-30 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0663 8f5e0a74fd527f3fcf93532ea8c9f89f 404 Pfam PF00037 4Fe-4S binding domain 144 167 1.2E-5 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0663 8f5e0a74fd527f3fcf93532ea8c9f89f 404 Pfam PF00037 4Fe-4S binding domain 99 119 9.3E-5 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0663 8f5e0a74fd527f3fcf93532ea8c9f89f 404 Gene3D G3DSA:3.30.70.20 102 197 1.3E-11 T 31-10-2018 AF_1972 58a636c95e8979c81ba3173e7e2a5524 349 Pfam PF04981 NMD3 family 25 242 7.3E-46 T 31-10-2018 IPR007064 Nmd3, N-terminal AF_2002 ee06afa692a04f61e79a13d59602e3fe 319 Pfam PF00155 Aminotransferase class I and II 1 313 3.1E-56 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AF_2002 ee06afa692a04f61e79a13d59602e3fe 319 Hamap MF_01023 Histidinol-phosphate aminotransferase [hisC]. 2 317 52.041 T 31-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AF_2002 ee06afa692a04f61e79a13d59602e3fe 319 Gene3D G3DSA:3.90.1150.10 2 313 1.2E-92 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AF_2002 ee06afa692a04f61e79a13d59602e3fe 319 TIGRFAM TIGR01141 hisC: histidinol-phosphate transaminase 1 316 1.6E-92 T 31-10-2018 IPR005861 Histidinol-phosphate aminotransferase family GO:0000105|GO:0004400 KEGG: 00340+2.6.1.9|KEGG: 00350+2.6.1.9|KEGG: 00360+2.6.1.9|KEGG: 00400+2.6.1.9|KEGG: 00401+2.6.1.9|KEGG: 00960+2.6.1.9 AF_2002 ee06afa692a04f61e79a13d59602e3fe 319 SUPERFAMILY SSF53383 1 314 1.02E-76 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AF_2002 ee06afa692a04f61e79a13d59602e3fe 319 Gene3D G3DSA:3.40.640.10 24 229 1.2E-92 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AF_1328 44180ecb58314835111b380f3ae7eceb 453 Gene3D G3DSA:3.50.50.60 3 342 3.2E-89 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1328 44180ecb58314835111b380f3ae7eceb 453 Pfam PF04324 BFD-like [2Fe-2S] binding domain 389 437 4.6E-8 T 31-10-2018 IPR007419 BFD-like [2Fe-2S]-binding domain AF_1328 44180ecb58314835111b380f3ae7eceb 453 SUPERFAMILY SSF51905 2 352 4.1E-45 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1328 44180ecb58314835111b380f3ae7eceb 453 Pfam PF01266 FAD dependent oxidoreductase 3 347 3.2E-55 T 31-10-2018 IPR006076 FAD dependent oxidoreductase GO:0016491|GO:0055114 AF_1328 44180ecb58314835111b380f3ae7eceb 453 Gene3D G3DSA:1.10.10.1100 389 442 2.7E-8 T 31-10-2018 AF_1328 44180ecb58314835111b380f3ae7eceb 453 Gene3D G3DSA:3.30.9.10 85 310 3.2E-89 T 31-10-2018 AF_2156 8757bcbfe5226fc7b614f70a44106085 437 Hamap MF_01264 CCA-adding enzyme [cca]. 1 437 157.981 T 31-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 AF_2156 8757bcbfe5226fc7b614f70a44106085 437 SUPERFAMILY SSF81301 1 141 8.72E-43 T 31-10-2018 AF_2156 8757bcbfe5226fc7b614f70a44106085 437 Gene3D G3DSA:1.10.1410.30 9 255 4.0E-100 T 31-10-2018 AF_2156 8757bcbfe5226fc7b614f70a44106085 437 Gene3D G3DSA:3.30.70.1550 340 383 2.3E-58 T 31-10-2018 AF_2156 8757bcbfe5226fc7b614f70a44106085 437 SUPERFAMILY SSF55003 241 434 3.77E-51 T 31-10-2018 IPR011068 Nucleotidyltransferase, class I-like, C-terminal GO:0003723|GO:0016779|GO:0031123 AF_2156 8757bcbfe5226fc7b614f70a44106085 437 TIGRFAM TIGR03671 cca_archaeal: CCA-adding enzyme 7 403 1.8E-144 T 31-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 AF_2156 8757bcbfe5226fc7b614f70a44106085 437 SUPERFAMILY SSF81631 144 256 1.31E-35 T 31-10-2018 AF_2156 8757bcbfe5226fc7b614f70a44106085 437 Pfam PF01909 Nucleotidyltransferase domain 27 132 1.7E-18 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AF_2156 8757bcbfe5226fc7b614f70a44106085 437 PIRSF PIRSF005335 1 437 8.3E-158 T 31-10-2018 IPR008229 tRNA nucleotidyltransferase, archaea GO:0001680|GO:0003723|GO:0004810 AF_2156 8757bcbfe5226fc7b614f70a44106085 437 Pfam PF09249 tRNA nucleotidyltransferase, second domain 146 254 2.3E-40 T 31-10-2018 IPR015329 tRNA nucleotidyltransferase, substrate binding GO:0004810|GO:0016437 AF_2156 8757bcbfe5226fc7b614f70a44106085 437 Gene3D G3DSA:3.30.460.10 16 143 4.0E-100 T 31-10-2018 AF_2156 8757bcbfe5226fc7b614f70a44106085 437 Gene3D G3DSA:3.30.70.590 265 420 2.3E-58 T 31-10-2018 AF_1239 3bd3a5bc819edf60d7fd5cc3a459da40 74 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 54 65 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1239 3bd3a5bc819edf60d7fd5cc3a459da40 74 Gene3D G3DSA:3.30.70.20 2 73 8.7E-11 T 31-10-2018 AF_1239 3bd3a5bc819edf60d7fd5cc3a459da40 74 SUPERFAMILY SSF54862 3 72 1.57E-12 T 31-10-2018 AF_1239 3bd3a5bc819edf60d7fd5cc3a459da40 74 Pfam PF12838 4Fe-4S dicluster domain 11 67 1.3E-6 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1950 ea30dc7342aa79d60c4da88fe02cb8b6 108 ProDom PD002610 PHOSPHORIBOSYL-AMP BIOSYNTHESIS CYCLOHYDROLASE HYDROLASE HISTIDINE AMINO-ACID PRA-CH PHOSPHORIBOSYL-ATP BIFUNCTIONAL INCLUDES: 48 101 2.0E-26 T 31-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AF_1950 ea30dc7342aa79d60c4da88fe02cb8b6 108 Hamap MF_01021 Phosphoribosyl-AMP cyclohydrolase [hisI]. 1 102 31.917 T 31-10-2018 IPR026660 Phosphoribosyl-AMP cyclohydrolase GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AF_1950 ea30dc7342aa79d60c4da88fe02cb8b6 108 Pfam PF01502 Phosphoribosyl-AMP cyclohydrolase 25 98 4.6E-37 T 31-10-2018 IPR002496 Phosphoribosyl-AMP cyclohydrolase domain GO:0000105|GO:0004635 KEGG: 00340+3.5.4.19 AF_1950 ea30dc7342aa79d60c4da88fe02cb8b6 108 SUPERFAMILY SSF141734 3 105 8.24E-50 T 31-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 AF_1950 ea30dc7342aa79d60c4da88fe02cb8b6 108 Gene3D G3DSA:3.10.20.400 1 89 1.3E-42 T 31-10-2018 IPR038019 Phosphoribosyl-AMP cyclohydrolase domain superfamily KEGG: 00340+3.5.4.19 AF_0806 0634eaff3ca9ee29db3187049d5d1b96 544 TIGRFAM TIGR00795 lctP: transporter, lactate permease (LctP) family 2 537 3.5E-191 T 31-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 AF_0806 0634eaff3ca9ee29db3187049d5d1b96 544 Pfam PF02652 L-lactate permease 1 534 2.2E-191 T 31-10-2018 IPR003804 L-lactate permease GO:0005887|GO:0015129|GO:0015727 AF_1343 ad5fa7d2e0f4d633b7d79c1c1fbf1ad3 307 SUPERFAMILY SSF56281 2 242 1.05E-41 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_1343 ad5fa7d2e0f4d633b7d79c1c1fbf1ad3 307 Pfam PF00753 Metallo-beta-lactamase superfamily 26 216 1.3E-21 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_1343 ad5fa7d2e0f4d633b7d79c1c1fbf1ad3 307 SMART SM00849 25 216 1.2E-32 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_1343 ad5fa7d2e0f4d633b7d79c1c1fbf1ad3 307 Gene3D G3DSA:3.60.15.10 7 264 3.9E-56 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_0327 822f7ca12e285b7c953b27e56fef1424 357 Gene3D G3DSA:3.40.50.2000 2 193 1.4E-19 T 31-10-2018 AF_0327 822f7ca12e285b7c953b27e56fef1424 357 Pfam PF13439 Glycosyltransferase Family 4 16 179 4.2E-18 T 31-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AF_0327 822f7ca12e285b7c953b27e56fef1424 357 SUPERFAMILY SSF53756 6 352 3.4E-70 T 31-10-2018 AF_0327 822f7ca12e285b7c953b27e56fef1424 357 Gene3D G3DSA:3.40.50.2000 194 343 1.1E-32 T 31-10-2018 AF_0327 822f7ca12e285b7c953b27e56fef1424 357 Pfam PF00534 Glycosyl transferases group 1 182 336 1.8E-36 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 AF_1927 0a0242ffa4e012a7948b1be0f6e29485 206 SUPERFAMILY SSF89392 33 202 1.8E-11 T 31-10-2018 IPR029046 Lipoprotein localisation LolA/LolB/LppX AF_1927 0a0242ffa4e012a7948b1be0f6e29485 206 Gene3D G3DSA:2.50.20.10 26 204 9.6E-14 T 31-10-2018 AF_1062 d3a9b22df7731e4be24f460ad04c6c47 177 Pfam PF01936 NYN domain 27 158 1.5E-24 T 31-10-2018 IPR021139 NYN domain, limkain-b1-type AF_1062 d3a9b22df7731e4be24f460ad04c6c47 177 ProDom PD010896 FAMILY DUF88 ARCHAEBACTERIAL PROTEIN MJ0482 PH0073 PF2040 VNG1608C MA3857 PF2039 28 100 9.0E-36 T 31-10-2018 AF_1062 d3a9b22df7731e4be24f460ad04c6c47 177 Gene3D G3DSA:3.40.50.1010 18 162 4.3E-16 T 31-10-2018 AF_1062 d3a9b22df7731e4be24f460ad04c6c47 177 TIGRFAM TIGR00288 TIGR00288: TIGR00288 family protein 6 162 1.2E-86 T 31-10-2018 IPR002790 Conserved hypothetical protein CHP00288 AF_1248 6baa18e2a125412c2964da0de4de5139 228 Pfam PF04474 Protein of unknown function (DUF554) 3 220 1.3E-76 T 31-10-2018 IPR007563 Protein of unknown function DUF554 AF_2380 37126eb06706f5e5bd51b49b12a69159 262 SUPERFAMILY SSF52540 1 252 9.3E-26 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2380 37126eb06706f5e5bd51b49b12a69159 262 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 91 102 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_2380 37126eb06706f5e5bd51b49b12a69159 262 Gene3D G3DSA:3.40.50.300 1 49 3.1E-7 T 31-10-2018 AF_2380 37126eb06706f5e5bd51b49b12a69159 262 Gene3D G3DSA:3.30.70.20 58 106 1.0E-8 T 31-10-2018 AF_2380 37126eb06706f5e5bd51b49b12a69159 262 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 246 5.0E-20 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AF_2380 37126eb06706f5e5bd51b49b12a69159 262 Gene3D G3DSA:3.40.50.300 107 262 1.3E-15 T 31-10-2018 AF_0602 950a1fc1ee27a36e871814c190d7df2c 396 SUPERFAMILY SSF53756 103 394 1.67E-31 T 31-10-2018 AF_0602 950a1fc1ee27a36e871814c190d7df2c 396 Gene3D G3DSA:3.40.50.2000 111 231 2.3E-26 T 31-10-2018 AF_0602 950a1fc1ee27a36e871814c190d7df2c 396 Pfam PF00534 Glycosyl transferases group 1 255 375 2.3E-22 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 AF_0602 950a1fc1ee27a36e871814c190d7df2c 396 Gene3D G3DSA:3.40.50.2000 232 376 2.3E-26 T 31-10-2018 AF_1022 2ea57ab5b6f2ebe3e626c217e284f4e8 127 TIGRFAM TIGR00637 ModE_repress: ModE molybdate transport repressor domain 17 113 2.3E-37 T 31-10-2018 IPR003725 Molybdenum-binding protein ModE, N-terminal AF_1022 2ea57ab5b6f2ebe3e626c217e284f4e8 127 SUPERFAMILY SSF46785 1 99 3.22E-22 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1022 2ea57ab5b6f2ebe3e626c217e284f4e8 127 Pfam PF00126 Bacterial regulatory helix-turn-helix protein, lysR family 23 82 7.4E-11 T 31-10-2018 IPR000847 Transcription regulator HTH, LysR GO:0003700|GO:0006355 AF_1022 2ea57ab5b6f2ebe3e626c217e284f4e8 127 Gene3D G3DSA:1.10.10.10 1 119 1.1E-32 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1729 d89ae46d44920acea981e7f71cf7bb30 310 Gene3D G3DSA:3.30.1330.20 200 308 8.1E-21 T 31-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 AF_1357 f67557f87509d3bf898f4cb309629016 297 Gene3D G3DSA:1.10.3720.10 55 295 3.0E-33 T 31-10-2018 IPR035906 MetI-like superfamily AF_1357 f67557f87509d3bf898f4cb309629016 297 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 83 288 1.8E-19 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AF_1357 f67557f87509d3bf898f4cb309629016 297 SUPERFAMILY SSF161098 8 285 7.06E-32 T 31-10-2018 IPR035906 MetI-like superfamily AF_1357 f67557f87509d3bf898f4cb309629016 297 TIGRFAM TIGR02138 phosphate_pstC: phosphate ABC transporter, permease protein PstC 6 292 8.8E-90 T 31-10-2018 IPR011864 Phosphate ABC transporter, permease protein PstC GO:0005315|GO:0006817|GO:0016021 AF_0325 50d4cebae0fa8ec9437df61f0efe88f5 352 TIGRFAM TIGR01208 rmlA_long: glucose-1-phosphate thymidylyltransferase 2 352 2.3E-171 T 31-10-2018 IPR005908 Glucose-1-phosphate thymidylyltransferase, long form AF_0325 50d4cebae0fa8ec9437df61f0efe88f5 352 SUPERFAMILY SSF53448 2 301 2.48E-76 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0325 50d4cebae0fa8ec9437df61f0efe88f5 352 Gene3D G3DSA:3.90.550.10 1 244 8.4E-72 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0325 50d4cebae0fa8ec9437df61f0efe88f5 352 Gene3D G3DSA:2.160.10.10 245 351 2.6E-7 T 31-10-2018 AF_0325 50d4cebae0fa8ec9437df61f0efe88f5 352 Pfam PF00483 Nucleotidyl transferase 2 236 1.7E-60 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AF_0381 f1a6a17d2936e064c673f0f6330c8180 251 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 208 5.2E-25 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AF_0381 f1a6a17d2936e064c673f0f6330c8180 251 Gene3D G3DSA:3.30.950.10 112 251 8.1E-56 T 31-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AF_0381 f1a6a17d2936e064c673f0f6330c8180 251 PIRSF PIRSF036432 1 246 5.3E-85 T 31-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 AF_0381 f1a6a17d2936e064c673f0f6330c8180 251 TIGRFAM TIGR00522 dph5: diphthine synthase 1 243 4.9E-115 T 31-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 AF_0381 f1a6a17d2936e064c673f0f6330c8180 251 Hamap MF_01084 Diphthine synthase [dphB]. 1 242 32.115 T 31-10-2018 IPR004551 Diphthine synthase GO:0004164|GO:0017183 Reactome: R-HSA-5358493 AF_0381 f1a6a17d2936e064c673f0f6330c8180 251 SUPERFAMILY SSF53790 1 246 1.15E-50 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AF_0381 f1a6a17d2936e064c673f0f6330c8180 251 Gene3D G3DSA:3.40.1010.10 1 111 1.5E-35 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AF_1909 07d6f16280bc6722c9843eefbe19525e 196 SUPERFAMILY SSF56053 20 103 2.62E-15 T 31-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1909 07d6f16280bc6722c9843eefbe19525e 196 Gene3D G3DSA:3.90.930.12 20 103 5.2E-20 T 31-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1909 07d6f16280bc6722c9843eefbe19525e 196 Gene3D G3DSA:3.90.930.12 104 196 2.9E-36 T 31-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1909 07d6f16280bc6722c9843eefbe19525e 196 TIGRFAM TIGR03653 uL6_arch: ribosomal protein uL6 22 195 1.2E-68 T 31-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 AF_1909 07d6f16280bc6722c9843eefbe19525e 196 Hamap MF_01365_A 50S ribosomal protein L6 [rplF]. 15 196 37.463 T 31-10-2018 IPR019907 Ribosomal protein L6P, archaea GO:0003735|GO:0005840|GO:0006412|GO:0019843 AF_1909 07d6f16280bc6722c9843eefbe19525e 196 ProSitePatterns PS00700 Ribosomal protein L6 signature 2. 174 195 - T 31-10-2018 IPR002359 Ribosomal protein L6, conserved site-2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1909 07d6f16280bc6722c9843eefbe19525e 196 SUPERFAMILY SSF56053 104 195 2.66E-29 T 31-10-2018 IPR036789 Ribosomal protein L6, alpha-beta domain superfamily GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1909 07d6f16280bc6722c9843eefbe19525e 196 PIRSF PIRSF002162 17 196 1.9E-32 T 31-10-2018 IPR000702 Ribosomal protein L6 GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1909 07d6f16280bc6722c9843eefbe19525e 196 Pfam PF00347 Ribosomal protein L6 26 103 2.5E-15 T 31-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1909 07d6f16280bc6722c9843eefbe19525e 196 Pfam PF00347 Ribosomal protein L6 115 189 7.7E-13 T 31-10-2018 IPR020040 Ribosomal protein L6, alpha-beta domain GO:0003735|GO:0005840|GO:0006412|GO:0019843 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0892 e09b01bbfb068ca63d5e2b3aa151024f 212 TIGRFAM TIGR01915 npdG: NADPH-dependent F420 reductase 1 211 4.8E-67 T 31-10-2018 IPR010185 NADPH-dependent F420 reductase GO:0006740|GO:0016651|GO:0050661|GO:0055114|GO:0070967 AF_0892 e09b01bbfb068ca63d5e2b3aa151024f 212 Pfam PF03807 NADP oxidoreductase coenzyme F420-dependent 2 99 2.5E-23 T 31-10-2018 IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal AF_0892 e09b01bbfb068ca63d5e2b3aa151024f 212 SUPERFAMILY SSF51735 1 207 6.71E-53 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0892 e09b01bbfb068ca63d5e2b3aa151024f 212 Gene3D G3DSA:3.40.50.720 1 212 9.3E-67 T 31-10-2018 AF_0075 857624aaf5b2354bebcee85f0c4825d6 413 Gene3D G3DSA:3.90.1640.30 9 245 3.9E-11 T 31-10-2018 AF_0075 857624aaf5b2354bebcee85f0c4825d6 413 SUPERFAMILY SSF64182 7 408 9.52E-40 T 31-10-2018 IPR038763 DHH phosphoesterase superfamily AF_1280 fb89d810fda132ddff68ea222336bd10 290 Hamap MF_00082 Acetylglutamate kinase [argB]. 19 283 49.817 T 31-10-2018 IPR037528 Acetylglutamate kinase ArgB GO:0003991|GO:0006526 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AF_1280 fb89d810fda132ddff68ea222336bd10 290 Gene3D G3DSA:3.40.1160.10 1 290 4.2E-100 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AF_1280 fb89d810fda132ddff68ea222336bd10 290 TIGRFAM TIGR00761 argB: acetylglutamate kinase 21 265 2.7E-90 T 31-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AF_1280 fb89d810fda132ddff68ea222336bd10 290 SUPERFAMILY SSF53633 2 289 3.14E-89 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AF_1280 fb89d810fda132ddff68ea222336bd10 290 Pfam PF00696 Amino acid kinase family 21 267 2.9E-48 T 31-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AF_1280 fb89d810fda132ddff68ea222336bd10 290 PIRSF PIRSF000728 5 290 5.6E-109 T 31-10-2018 IPR004662 Acetylglutamate kinase family GO:0005737 KEGG: 00220+2.7.2.8|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AF_0851 2997e4944146256fc7149eafb6bbb71f 464 SUPERFAMILY SSF53613 210 458 4.03E-56 T 31-10-2018 IPR029056 Ribokinase-like AF_0851 2997e4944146256fc7149eafb6bbb71f 464 Hamap MF_01965 ADP-dependent (S)-NAD(P)H-hydrate dehydratase [nnrD]. 203 463 20.796 T 31-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AF_0851 2997e4944146256fc7149eafb6bbb71f 464 Pfam PF03853 YjeF-related protein N-terminus 26 177 1.9E-43 T 31-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AF_0851 2997e4944146256fc7149eafb6bbb71f 464 Hamap MF_01966 NAD(P)H-hydrate epimerase [nnrE]. 4 196 23.967 T 31-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AF_0851 2997e4944146256fc7149eafb6bbb71f 464 PIRSF PIRSF017184 1 462 8.0E-102 T 31-10-2018 IPR030677 Bifunctional NAD(P)H-hydrate repair enzyme Nnr GO:0052855 MetaCyc: PWY-6938 AF_0851 2997e4944146256fc7149eafb6bbb71f 464 Gene3D G3DSA:3.40.50.10260 2 202 3.7E-61 T 31-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 AF_0851 2997e4944146256fc7149eafb6bbb71f 464 TIGRFAM TIGR00196 yjeF_cterm: YjeF family C-terminal domain 200 458 1.8E-95 T 31-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AF_0851 2997e4944146256fc7149eafb6bbb71f 464 TIGRFAM TIGR00197 yjeF_nterm: YjeF family N-terminal domain 3 197 1.3E-78 T 31-10-2018 IPR004443 YjeF N-terminal domain MetaCyc: PWY-6938 AF_0851 2997e4944146256fc7149eafb6bbb71f 464 Pfam PF01256 Carbohydrate kinase 226 455 5.7E-47 T 31-10-2018 IPR000631 ATP-dependent (S)-NAD(P)H-hydrate dehydratase GO:0052855 Reactome: R-HSA-197264 AF_0851 2997e4944146256fc7149eafb6bbb71f 464 Gene3D G3DSA:3.40.1190.20 209 463 6.3E-68 T 31-10-2018 IPR029056 Ribokinase-like AF_0851 2997e4944146256fc7149eafb6bbb71f 464 SUPERFAMILY SSF64153 1 224 1.83E-60 T 31-10-2018 IPR036652 YjeF N-terminal domain superfamily MetaCyc: PWY-6938 AF_1360 d70f02fcb36e56ab307cdd1abd416561 196 Gene3D G3DSA:1.20.58.220 1 103 2.2E-20 T 31-10-2018 IPR038078 PhoU-like domain superfamily AF_1360 d70f02fcb36e56ab307cdd1abd416561 196 Pfam PF01895 PhoU domain 15 99 5.9E-14 T 31-10-2018 IPR026022 PhoU domain AF_1360 d70f02fcb36e56ab307cdd1abd416561 196 Pfam PF01895 PhoU domain 115 182 3.1E-6 T 31-10-2018 IPR026022 PhoU domain AF_1360 d70f02fcb36e56ab307cdd1abd416561 196 TIGRFAM TIGR02135 phoU_full: phosphate transport system regulatory protein PhoU 2 192 8.8E-46 T 31-10-2018 IPR028366 Phosphate transport system protein PhoU GO:0005737|GO:0030643|GO:0045936 AF_1360 d70f02fcb36e56ab307cdd1abd416561 196 SUPERFAMILY SSF109755 2 193 4.6E-34 T 31-10-2018 AF_1360 d70f02fcb36e56ab307cdd1abd416561 196 Gene3D G3DSA:1.20.58.220 104 194 4.5E-7 T 31-10-2018 IPR038078 PhoU-like domain superfamily AF_0913 0294b52e5e68e6dc262876c36adb8094 112 SUPERFAMILY SSF75169 1 112 4.32E-30 T 31-10-2018 IPR027396 DsrEFH-like AF_0913 0294b52e5e68e6dc262876c36adb8094 112 Pfam PF02635 DsrE/DsrF-like family 2 112 4.0E-18 T 31-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein AF_0913 0294b52e5e68e6dc262876c36adb8094 112 Gene3D G3DSA:3.40.1260.10 1 112 8.9E-34 T 31-10-2018 IPR027396 DsrEFH-like AF_1874 acaa45feda00458ee63279fe89935e4a 546 TIGRFAM TIGR01587 cas3_core: CRISPR-associated helicase Cas3 40 405 1.1E-120 T 31-10-2018 IPR006474 Helicase Cas3, CRISPR-associated, core AF_1874 acaa45feda00458ee63279fe89935e4a 546 Pfam PF00271 Helicase conserved C-terminal domain 253 361 4.4E-8 T 31-10-2018 IPR001650 Helicase, C-terminal AF_1874 acaa45feda00458ee63279fe89935e4a 546 Gene3D G3DSA:3.40.50.300 20 222 1.8E-14 T 31-10-2018 AF_1874 acaa45feda00458ee63279fe89935e4a 546 Gene3D G3DSA:3.40.50.300 223 410 2.2E-15 T 31-10-2018 AF_1874 acaa45feda00458ee63279fe89935e4a 546 SMART SM00490 278 361 2.9E-6 T 31-10-2018 IPR001650 Helicase, C-terminal AF_1874 acaa45feda00458ee63279fe89935e4a 546 SMART SM00487 17 232 2.3E-18 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AF_1874 acaa45feda00458ee63279fe89935e4a 546 Pfam PF00270 DEAD/DEAH box helicase 39 206 4.5E-11 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AF_1874 acaa45feda00458ee63279fe89935e4a 546 SUPERFAMILY SSF52540 37 373 2.0E-29 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0962 d93a9def35c0f34953d850ac423ed03f 390 SUPERFAMILY SSF53822 35 387 7.66E-50 T 31-10-2018 IPR028082 Periplasmic binding protein-like I AF_0962 d93a9def35c0f34953d850ac423ed03f 390 Gene3D G3DSA:3.40.50.2300 35 353 3.1E-49 T 31-10-2018 AF_0962 d93a9def35c0f34953d850ac423ed03f 390 Pfam PF13458 Periplasmic binding protein 34 354 7.4E-39 T 31-10-2018 IPR028081 Leucine-binding protein domain AF_0962 d93a9def35c0f34953d850ac423ed03f 390 Gene3D G3DSA:3.40.50.2300 147 283 3.1E-49 T 31-10-2018 AF_0343 2285854d8fd0694333f714564ab78740 191 SUPERFAMILY SSF52218 1 190 1.27E-50 T 31-10-2018 IPR029039 Flavoprotein-like superfamily AF_0343 2285854d8fd0694333f714564ab78740 191 TIGRFAM TIGR01755 flav_wrbA: NAD(P)H:quinone oxidoreductase, type IV 3 190 5.6E-52 T 31-10-2018 IPR010089 Flavoprotein WrbA-like GO:0003955|GO:0010181 KEGG: 00130+1.6.5.2|MetaCyc: PWY-7731 AF_0343 2285854d8fd0694333f714564ab78740 191 ProSitePatterns PS00201 Flavodoxin signature. 6 22 - T 31-10-2018 IPR001226 Flavodoxin, conserved site GO:0009055|GO:0010181 AF_0343 2285854d8fd0694333f714564ab78740 191 Gene3D G3DSA:3.40.50.360 1 191 2.4E-64 T 31-10-2018 IPR029039 Flavoprotein-like superfamily AF_0343 2285854d8fd0694333f714564ab78740 191 Pfam PF03358 NADPH-dependent FMN reductase 3 145 2.7E-14 T 31-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AF_0499 bdfa4496a0f156b7f819019639bdcc5d 269 Pfam PF13247 4Fe-4S dicluster domain 112 166 1.2E-10 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0499 bdfa4496a0f156b7f819019639bdcc5d 269 Gene3D G3DSA:3.30.70.20 58 268 1.5E-50 T 31-10-2018 AF_0499 bdfa4496a0f156b7f819019639bdcc5d 269 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 150 161 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0499 bdfa4496a0f156b7f819019639bdcc5d 269 SUPERFAMILY SSF54862 39 264 1.36E-49 T 31-10-2018 AF_1780 2762369ed313fb490caf380e692e6065 545 Gene3D G3DSA:3.40.50.970 353 539 1.6E-45 T 31-10-2018 AF_1780 2762369ed313fb490caf380e692e6065 545 Gene3D G3DSA:3.40.50.970 1 178 5.8E-52 T 31-10-2018 AF_1780 2762369ed313fb490caf380e692e6065 545 SUPERFAMILY SSF52467 178 348 4.43E-38 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AF_1780 2762369ed313fb490caf380e692e6065 545 Pfam PF02776 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain 1 169 6.3E-48 T 31-10-2018 IPR012001 Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain GO:0030976 AF_1780 2762369ed313fb490caf380e692e6065 545 Gene3D G3DSA:3.40.50.1220 179 351 1.3E-39 T 31-10-2018 AF_1780 2762369ed313fb490caf380e692e6065 545 SUPERFAMILY SSF52518 1 169 2.99E-44 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold AF_1780 2762369ed313fb490caf380e692e6065 545 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 384 526 2.2E-34 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AF_1780 2762369ed313fb490caf380e692e6065 545 SUPERFAMILY SSF52518 361 536 2.16E-46 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold AF_1780 2762369ed313fb490caf380e692e6065 545 Pfam PF00205 Thiamine pyrophosphate enzyme, central domain 186 320 8.3E-30 T 31-10-2018 IPR012000 Thiamine pyrophosphate enzyme, central domain GO:0000287|GO:0030976 AF_0082 3734c081b33900f779d9a594043ecb0d 282 Pfam PF00589 Phage integrase family 87 207 8.3E-11 T 31-10-2018 IPR002104 Integrase, catalytic domain GO:0003677|GO:0006310|GO:0015074 AF_0082 3734c081b33900f779d9a594043ecb0d 282 SUPERFAMILY SSF56349 19 227 1.03E-20 T 31-10-2018 IPR011010 DNA breaking-rejoining enzyme, catalytic core GO:0003677 AF_0082 3734c081b33900f779d9a594043ecb0d 282 Gene3D G3DSA:1.10.443.10 74 223 1.4E-14 T 31-10-2018 IPR013762 Integrase-like, catalytic domain superfamily GO:0003677|GO:0006310|GO:0015074 AF_1554 b49d62456e2249e7e86dc67ef5671c48 300 Gene3D G3DSA:3.50.50.60 2 292 2.6E-104 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1554 b49d62456e2249e7e86dc67ef5671c48 300 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 287 2.1E-51 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AF_1554 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 99 117 7.4E-36 T 31-10-2018 AF_1554 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 224 240 7.4E-36 T 31-10-2018 AF_1554 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 141 159 7.4E-36 T 31-10-2018 AF_1554 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 4 23 7.4E-36 T 31-10-2018 AF_1554 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 251 273 7.4E-36 T 31-10-2018 AF_1554 b49d62456e2249e7e86dc67ef5671c48 300 TIGRFAM TIGR01292 TRX_reduct: thioredoxin-disulfide reductase 2 298 5.1E-117 T 31-10-2018 IPR005982 Thioredoxin reductase GO:0004791|GO:0005737|GO:0019430|GO:0055114 KEGG: 00450+1.8.1.9 AF_1554 b49d62456e2249e7e86dc67ef5671c48 300 Gene3D G3DSA:3.50.50.60 111 232 2.6E-104 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1554 b49d62456e2249e7e86dc67ef5671c48 300 SUPERFAMILY SSF51905 1 298 3.58E-54 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1554 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 188 204 4.3E-60 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AF_1554 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 36 51 4.3E-60 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AF_1554 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 100 108 4.3E-60 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AF_1554 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 226 247 4.3E-60 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AF_1554 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 55 65 4.3E-60 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AF_1554 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 3 25 4.3E-60 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AF_1554 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 261 279 4.3E-60 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AF_1554 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 122 134 4.3E-60 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AF_1554 b49d62456e2249e7e86dc67ef5671c48 300 PRINTS PR00469 Pyridine nucleotide disulphide reductase class-II signature 137 161 4.3E-60 T 31-10-2018 IPR000103 Pyridine nucleotide-disulphide oxidoreductase, class-II GO:0016491|GO:0055114 AF_2285 21db322ddf9606002cecf257aa65af1b 146 Hamap MF_01315 30S ribosomal protein S13 [rpsM]. 6 145 24.585 T 31-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2285 21db322ddf9606002cecf257aa65af1b 146 PIRSF PIRSF002134 1 146 7.5E-43 T 31-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2285 21db322ddf9606002cecf257aa65af1b 146 SUPERFAMILY SSF46946 7 141 7.06E-32 T 31-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AF_2285 21db322ddf9606002cecf257aa65af1b 146 Gene3D G3DSA:1.10.8.50 1 73 2.6E-23 T 31-10-2018 AF_2285 21db322ddf9606002cecf257aa65af1b 146 Pfam PF00416 Ribosomal protein S13/S18 8 135 2.3E-41 T 31-10-2018 IPR001892 Ribosomal protein S13 GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2285 21db322ddf9606002cecf257aa65af1b 146 TIGRFAM TIGR03629 uS13_arch: ribosomal protein uS13 3 145 1.9E-63 T 31-10-2018 IPR019977 Ribosomal protein S13, archaeal GO:0003723|GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_2285 21db322ddf9606002cecf257aa65af1b 146 Gene3D G3DSA:4.10.910.10 85 135 1.3E-18 T 31-10-2018 IPR027437 30s ribosomal protein S13, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2285 21db322ddf9606002cecf257aa65af1b 146 ProSitePatterns PS00646 Ribosomal protein S13 signature. 114 127 - T 31-10-2018 IPR018269 Ribosomal protein S13, conserved site GO:0003723|GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1902 4d069e73201feacf54534eff8b528cd2 493 Hamap MF_01465 Protein translocase subunit SecY [secY]. 18 486 22.206 T 31-10-2018 IPR026593 Protein translocase subunit SecY AF_1902 4d069e73201feacf54534eff8b528cd2 493 Pfam PF00344 SecY translocase 73 470 2.0E-71 T 31-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AF_1902 4d069e73201feacf54534eff8b528cd2 493 ProSitePatterns PS00755 Protein secY signature 1. 73 92 - T 31-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AF_1902 4d069e73201feacf54534eff8b528cd2 493 TIGRFAM TIGR00967 3a0501s007: preprotein translocase, SecY subunit 28 479 7.0E-87 T 31-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AF_1902 4d069e73201feacf54534eff8b528cd2 493 PIRSF PIRSF004557 5 493 1.9E-113 T 31-10-2018 IPR002208 SecY/SEC61-alpha family GO:0015031|GO:0016020 Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AF_1902 4d069e73201feacf54534eff8b528cd2 493 Pfam PF10559 Plug domain of Sec61p 39 72 1.9E-11 T 31-10-2018 IPR019561 Translocon Sec61/SecY, plug domain Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AF_1902 4d069e73201feacf54534eff8b528cd2 493 SUPERFAMILY SSF103491 8 476 1.44E-102 T 31-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AF_1902 4d069e73201feacf54534eff8b528cd2 493 PRINTS PR00303 Preprotein translocase SecY subunit signature 177 200 4.3E-7 T 31-10-2018 AF_1902 4d069e73201feacf54534eff8b528cd2 493 PRINTS PR00303 Preprotein translocase SecY subunit signature 31 49 4.3E-7 T 31-10-2018 AF_1902 4d069e73201feacf54534eff8b528cd2 493 PRINTS PR00303 Preprotein translocase SecY subunit signature 151 176 4.3E-7 T 31-10-2018 AF_1902 4d069e73201feacf54534eff8b528cd2 493 Gene3D G3DSA:1.10.3370.10 5 491 4.0E-149 T 31-10-2018 IPR023201 SecY domain superfamily Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AF_1902 4d069e73201feacf54534eff8b528cd2 493 ProSitePatterns PS00756 Protein secY signature 2. 170 187 - T 31-10-2018 IPR030659 SecY conserved site Reactome: R-HSA-1236974|Reactome: R-HSA-1799339|Reactome: R-HSA-381038 AF_2417 9e2a0fa98b256ba0cacacb8b6c8353e7 122 Gene3D G3DSA:1.10.12.20 4 46 6.5E-6 T 31-10-2018 AF_2417 9e2a0fa98b256ba0cacacb8b6c8353e7 122 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 8 40 4.3E-10 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AF_2417 9e2a0fa98b256ba0cacacb8b6c8353e7 122 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 46 101 1.4E-15 T 31-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AF_2417 9e2a0fa98b256ba0cacacb8b6c8353e7 122 SUPERFAMILY SSF50249 4 106 1.25E-26 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0869 da1203e67e6ffaa81ee9e5801d09ea36 108 Gene3D G3DSA:3.30.110.70 5 108 3.0E-34 T 31-10-2018 AF_0869 da1203e67e6ffaa81ee9e5801d09ea36 108 Hamap MF_00338 UPF0145 protein YbjQ [ybjQ]. 5 107 25.937 T 31-10-2018 IPR002765 Uncharacterised protein family UPF0145 AF_0869 da1203e67e6ffaa81ee9e5801d09ea36 108 Pfam PF01906 Putative heavy-metal-binding 5 106 2.0E-39 T 31-10-2018 IPR002765 Uncharacterised protein family UPF0145 AF_0869 da1203e67e6ffaa81ee9e5801d09ea36 108 SUPERFAMILY SSF117782 5 107 1.44E-37 T 31-10-2018 IPR035439 UPF0145 domain superfamily AF_0799 8bda5cb7838ebe7c3af06b6026b080eb 178 SUPERFAMILY SSF56300 2 176 2.53E-42 T 31-10-2018 AF_0799 8bda5cb7838ebe7c3af06b6026b080eb 178 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 4 156 2.2E-20 T 31-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 AF_0799 8bda5cb7838ebe7c3af06b6026b080eb 178 Gene3D G3DSA:3.60.21.10 1 178 2.1E-50 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like AF_0799 8bda5cb7838ebe7c3af06b6026b080eb 178 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 4 160 3.9E-54 T 31-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 AF_1033 155e9938f1700b1ca141de92f0fd1076 371 Pfam PF09376 NurA domain 44 338 3.5E-50 T 31-10-2018 IPR018977 NurA domain AF_1033 155e9938f1700b1ca141de92f0fd1076 371 PIRSF PIRSF018871 193 370 3.8E-71 T 31-10-2018 IPR016738 DNA double-strand break repair nuclease NurA-like AF_1033 155e9938f1700b1ca141de92f0fd1076 371 PIRSF PIRSF018871 1 196 2.1E-74 T 31-10-2018 IPR016738 DNA double-strand break repair nuclease NurA-like AF_1033 155e9938f1700b1ca141de92f0fd1076 371 SMART SM00933 43 338 1.9E-36 T 31-10-2018 IPR018977 NurA domain AF_0862 345e491d91c9c4ce50ce2992b74f7b55 482 Pfam PF01139 tRNA-splicing ligase RtcB 48 482 4.9E-174 T 31-10-2018 IPR001233 tRNA-splicing ligase, RtcB GO:0006396|GO:0008452 Reactome: R-HSA-6784531 AF_0862 345e491d91c9c4ce50ce2992b74f7b55 482 SUPERFAMILY SSF103365 6 482 3.66E-178 T 31-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 AF_0862 345e491d91c9c4ce50ce2992b74f7b55 482 Gene3D G3DSA:3.90.1860.10 4 482 2.7E-207 T 31-10-2018 IPR036025 tRNA-splicing ligase RtcB-like superfamily GO:0006396|GO:0008452 Reactome: R-HSA-6784531 AF_1648 0c4e3c6ba7a56ef9ec631224a15a3899 303 Pfam PF01040 UbiA prenyltransferase family 30 261 3.8E-28 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AF_1648 0c4e3c6ba7a56ef9ec631224a15a3899 303 Gene3D G3DSA:1.20.120.1780 176 302 7.5E-8 T 31-10-2018 AF_1648 0c4e3c6ba7a56ef9ec631224a15a3899 303 Gene3D G3DSA:1.10.357.140 24 175 1.0E-11 T 31-10-2018 AF_1976 04d47899da85b387418b42ade690b54c 398 Hamap MF_00553 Proteasome-activating nucleotidase [pan]. 1 397 49.929 T 31-10-2018 IPR023501 Proteasome-activating nucleotidase PAN AF_1976 04d47899da85b387418b42ade690b54c 398 SMART SM00382 174 313 1.0E-24 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1976 04d47899da85b387418b42ade690b54c 398 Gene3D G3DSA:1.10.8.60 312 383 4.9E-29 T 31-10-2018 AF_1976 04d47899da85b387418b42ade690b54c 398 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 178 311 2.4E-45 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AF_1976 04d47899da85b387418b42ade690b54c 398 TIGRFAM TIGR01242 26Sp45: 26S proteasome subunit P45 family 21 383 1.6E-210 T 31-10-2018 IPR005937 26S proteasome regulatory subunit P45-like GO:0005737|GO:0016787|GO:0030163 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AF_1976 04d47899da85b387418b42ade690b54c 398 SUPERFAMILY SSF52540 136 385 2.52E-72 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1976 04d47899da85b387418b42ade690b54c 398 Gene3D G3DSA:3.40.50.300 131 311 2.0E-70 T 31-10-2018 AF_1976 04d47899da85b387418b42ade690b54c 398 Gene3D G3DSA:2.40.50.140 26 130 2.0E-32 T 31-10-2018 AF_1976 04d47899da85b387418b42ade690b54c 398 ProSitePatterns PS00674 AAA-protein family signature. 281 299 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AF_1445 e2dec2235fce373b9453d77885a84550 495 Pfam PF07728 AAA domain (dynein-related subfamily) 165 280 1.3E-8 T 31-10-2018 IPR011704 ATPase, dynein-related, AAA domain GO:0005524|GO:0016887 AF_1445 e2dec2235fce373b9453d77885a84550 495 SUPERFAMILY SSF52540 80 397 2.54E-27 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1445 e2dec2235fce373b9453d77885a84550 495 Gene3D G3DSA:3.40.50.300 77 285 7.2E-33 T 31-10-2018 AF_1445 e2dec2235fce373b9453d77885a84550 495 Pfam PF01078 Magnesium chelatase, subunit ChlI 81 127 6.2E-5 T 31-10-2018 IPR000523 Magnesium chelatase ChlI domain AF_2216 f27b1e7eefc619ebb6c4caaf6f9fdf97 140 SUPERFAMILY SSF51230 66 139 9.03E-24 T 31-10-2018 IPR011053 Single hybrid motif AF_2216 f27b1e7eefc619ebb6c4caaf6f9fdf97 140 ProSitePatterns PS00188 Biotin-requiring enzymes attachment site. 96 113 - T 31-10-2018 IPR001882 Biotin-binding site Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AF_2216 f27b1e7eefc619ebb6c4caaf6f9fdf97 140 Pfam PF00364 Biotin-requiring enzyme 73 139 9.5E-22 T 31-10-2018 IPR000089 Biotin/lipoyl attachment AF_2216 f27b1e7eefc619ebb6c4caaf6f9fdf97 140 Gene3D G3DSA:2.40.50.100 63 140 1.8E-26 T 31-10-2018 AF_1164 8bff5edb33dc6e1a9919665bedf872a0 342 SUPERFAMILY SSF103486 13 341 3.01E-78 T 31-10-2018 IPR036079 V-type ATP synthase subunit C-like Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AF_1164 8bff5edb33dc6e1a9919665bedf872a0 342 Hamap MF_00314 V-type ATP synthase subunit C [atpC]. 9 341 27.323 T 31-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 AF_1164 8bff5edb33dc6e1a9919665bedf872a0 342 Gene3D G3DSA:1.20.1690.10 91 189 8.9E-87 T 31-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AF_1164 8bff5edb33dc6e1a9919665bedf872a0 342 Gene3D G3DSA:1.10.132.50 13 334 8.9E-87 T 31-10-2018 AF_1164 8bff5edb33dc6e1a9919665bedf872a0 342 Pfam PF01992 ATP synthase (C/AC39) subunit 16 337 1.4E-68 T 31-10-2018 IPR002843 ATPase, V0 complex, c/d subunit Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AF_1164 8bff5edb33dc6e1a9919665bedf872a0 342 Gene3D G3DSA:1.20.1690.10 198 300 8.9E-87 T 31-10-2018 IPR035067 V-type ATPase subunit c Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AF_1164 8bff5edb33dc6e1a9919665bedf872a0 342 TIGRFAM TIGR02923 AhaC: ATP synthase A1, C subunit 10 340 3.2E-140 T 31-10-2018 IPR014272 ATPase, V0 complex, c subunit GO:0033179|GO:0046961 AF_1470 22b2f6abb412678ae1e5dfed9e2de7d3 409 Pfam PF02687 FtsX-like permease family 310 402 8.8E-12 T 31-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AF_1470 22b2f6abb412678ae1e5dfed9e2de7d3 409 Pfam PF12704 MacB-like periplasmic core domain 51 249 3.4E-26 T 31-10-2018 IPR025857 MacB-like periplasmic core domain AF_1921 a4ad626dd1f7ac4a6315995a5ac1209c 133 SUPERFAMILY SSF54570 52 117 3.53E-25 T 31-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1921 a4ad626dd1f7ac4a6315995a5ac1209c 133 Gene3D G3DSA:3.30.860.20 2 133 3.2E-49 T 31-10-2018 IPR023575 Ribosomal protein S19, superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1921 a4ad626dd1f7ac4a6315995a5ac1209c 133 Hamap MF_00531 30S ribosomal protein S19 [rpsS]. 39 122 23.47 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1921 a4ad626dd1f7ac4a6315995a5ac1209c 133 PRINTS PR00975 Ribosomal protein S19 family signature 66 85 1.8E-17 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1921 a4ad626dd1f7ac4a6315995a5ac1209c 133 PRINTS PR00975 Ribosomal protein S19 family signature 86 98 1.8E-17 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1921 a4ad626dd1f7ac4a6315995a5ac1209c 133 PRINTS PR00975 Ribosomal protein S19 family signature 98 113 1.8E-17 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1921 a4ad626dd1f7ac4a6315995a5ac1209c 133 PIRSF PIRSF002144 2 133 2.3E-37 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1921 a4ad626dd1f7ac4a6315995a5ac1209c 133 Pfam PF00203 Ribosomal protein S19 41 116 1.4E-28 T 31-10-2018 IPR002222 Ribosomal protein S19/S15 GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1921 a4ad626dd1f7ac4a6315995a5ac1209c 133 TIGRFAM TIGR01025 uS19_arch: ribosomal protein uS19 10 133 8.7E-64 T 31-10-2018 IPR005713 Ribosomal protein S19A/S15e GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1921 a4ad626dd1f7ac4a6315995a5ac1209c 133 ProSitePatterns PS00323 Ribosomal protein S19 signature. 86 110 - T 31-10-2018 IPR020934 Ribosomal protein S19 conserved site GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1785 5cd4cfd4352fd99f8309d2bcd43ff0a3 191 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 62 125 5.5E-18 T 31-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 AF_1785 5cd4cfd4352fd99f8309d2bcd43ff0a3 191 Gene3D G3DSA:1.10.10.10 1 65 9.5E-22 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1785 5cd4cfd4352fd99f8309d2bcd43ff0a3 191 SMART SM00529 23 123 1.3E-45 T 31-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 AF_1785 5cd4cfd4352fd99f8309d2bcd43ff0a3 191 SUPERFAMILY SSF46785 2 60 2.33E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1785 5cd4cfd4352fd99f8309d2bcd43ff0a3 191 Gene3D G3DSA:1.10.60.10 66 120 2.8E-9 T 31-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 AF_1785 5cd4cfd4352fd99f8309d2bcd43ff0a3 191 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 1 59 7.7E-27 T 31-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 AF_1785 5cd4cfd4352fd99f8309d2bcd43ff0a3 191 SUPERFAMILY SSF47979 62 131 3.66E-11 T 31-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 AF_2180 e759ba89de757e0e0a4fee075d845708 175 TIGRFAM TIGR00040 yfcE: phosphodiesterase, MJ0936 family 3 153 9.3E-47 T 31-10-2018 IPR000979 Phosphodiesterase MJ0936/Vps29 Reactome: R-HSA-3238698 AF_2180 e759ba89de757e0e0a4fee075d845708 175 SUPERFAMILY SSF56300 1 156 4.52E-33 T 31-10-2018 AF_2180 e759ba89de757e0e0a4fee075d845708 175 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 3 139 1.1E-23 T 31-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 AF_2180 e759ba89de757e0e0a4fee075d845708 175 Gene3D G3DSA:3.60.21.10 1 157 5.2E-36 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like AF_1133 e1232da74392d68e9ae63466a2dcfa51 197 SUPERFAMILY SSF52313 8 193 2.75E-58 T 31-10-2018 IPR023591 Ribosomal protein S2, flavodoxin-like domain superfamily AF_1133 e1232da74392d68e9ae63466a2dcfa51 197 Hamap MF_00291_B 30S ribosomal protein S2 [rpsB]. 8 184 9.641 T 31-10-2018 IPR005706 Ribosomal protein S2, bacteria/mitochondria/plastid GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-5368286|Reactome: R-HSA-5389840|Reactome: R-HSA-5419276 AF_1133 e1232da74392d68e9ae63466a2dcfa51 197 PRINTS PR00395 Ribosomal protein S2 signature 12 30 8.2E-26 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1133 e1232da74392d68e9ae63466a2dcfa51 197 PRINTS PR00395 Ribosomal protein S2 signature 90 107 8.2E-26 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1133 e1232da74392d68e9ae63466a2dcfa51 197 PRINTS PR00395 Ribosomal protein S2 signature 42 51 8.2E-26 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1133 e1232da74392d68e9ae63466a2dcfa51 197 PRINTS PR00395 Ribosomal protein S2 signature 153 167 8.2E-26 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1133 e1232da74392d68e9ae63466a2dcfa51 197 PRINTS PR00395 Ribosomal protein S2 signature 115 132 8.2E-26 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1133 e1232da74392d68e9ae63466a2dcfa51 197 PRINTS PR00395 Ribosomal protein S2 signature 132 143 8.2E-26 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1133 e1232da74392d68e9ae63466a2dcfa51 197 ProSitePatterns PS00963 Ribosomal protein S2 signature 2. 115 139 - T 31-10-2018 IPR018130 Ribosomal protein S2, conserved site GO:0003735|GO:0005840|GO:0006412 AF_1133 e1232da74392d68e9ae63466a2dcfa51 197 Gene3D G3DSA:3.40.50.10490 11 197 1.3E-77 T 31-10-2018 AF_1133 e1232da74392d68e9ae63466a2dcfa51 197 TIGRFAM TIGR01012 uS2_euk_arch: ribosomal protein uS2 7 196 3.0E-95 T 31-10-2018 IPR005707 Ribosomal protein S2, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1133 e1232da74392d68e9ae63466a2dcfa51 197 Pfam PF00318 Ribosomal protein S2 16 106 6.2E-13 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1133 e1232da74392d68e9ae63466a2dcfa51 197 Pfam PF00318 Ribosomal protein S2 113 179 7.9E-15 T 31-10-2018 IPR001865 Ribosomal protein S2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1133 e1232da74392d68e9ae63466a2dcfa51 197 Hamap MF_00291_A 30S ribosomal protein S2 [rpsB]. 4 197 48.909 T 31-10-2018 IPR023454 Ribosomal protein S2, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_2432 11a256164863313b6a6e1d447cbb93e2 147 SUPERFAMILY SSF81301 6 116 7.27E-15 T 31-10-2018 AF_2432 11a256164863313b6a6e1d447cbb93e2 147 Gene3D G3DSA:3.30.460.10 1 102 6.6E-13 T 31-10-2018 AF_2432 11a256164863313b6a6e1d447cbb93e2 147 Pfam PF01909 Nucleotidyltransferase domain 9 89 1.5E-12 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AF_1264 ac005326a11562d1e72cbe901d151096 256 Pfam PF12840 Helix-turn-helix domain 171 225 2.6E-9 T 31-10-2018 AF_1264 ac005326a11562d1e72cbe901d151096 256 SMART SM00418 168 246 1.0E-16 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_1264 ac005326a11562d1e72cbe901d151096 256 SUPERFAMILY SSF46785 153 233 1.02E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1264 ac005326a11562d1e72cbe901d151096 256 PIRSF PIRSF018357 1 252 3.3E-86 T 31-10-2018 IPR016723 Transcription regulator, ArsR, predicted AF_1264 ac005326a11562d1e72cbe901d151096 256 Gene3D G3DSA:1.10.10.10 148 241 6.6E-16 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1333 c707e64471163c2a1b1cd13f55ba63ce 93 Gene3D G3DSA:3.10.450.80 1 92 1.4E-32 T 31-10-2018 AF_1333 c707e64471163c2a1b1cd13f55ba63ce 93 SUPERFAMILY SSF57829 1 91 2.75E-33 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AF_1333 c707e64471163c2a1b1cd13f55ba63ce 93 Hamap MF_01476 50S ribosomal protein L44e [rpl44e]. 1 91 22.568 T 31-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1333 c707e64471163c2a1b1cd13f55ba63ce 93 Pfam PF00935 Ribosomal protein L44 16 90 1.3E-25 T 31-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1333 c707e64471163c2a1b1cd13f55ba63ce 93 ProDom PD002841 RIBOSOMAL RIBONUCLEOPROTEIN 60S L44 L44E L41 RESISTANCE 50S ANTIBIOTIC CYCLOHEXIMIDE 9 92 1.0E-43 T 31-10-2018 IPR000552 Ribosomal protein L44e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0673 350c1248a614e71add2003cc9ca08b62 130 SMART SM00422 7 75 2.5E-31 T 31-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AF_0673 350c1248a614e71add2003cc9ca08b62 130 Gene3D G3DSA:1.10.1660.10 1 127 1.8E-31 T 31-10-2018 AF_0673 350c1248a614e71add2003cc9ca08b62 130 SUPERFAMILY SSF46955 7 117 9.16E-29 T 31-10-2018 IPR009061 Putative DNA-binding domain superfamily AF_0673 350c1248a614e71add2003cc9ca08b62 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 19 32 1.6E-6 T 31-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AF_0673 350c1248a614e71add2003cc9ca08b62 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 42 62 1.6E-6 T 31-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AF_0673 350c1248a614e71add2003cc9ca08b62 130 PRINTS PR00040 MerR bacterial regulatory protein HTH signature 8 19 1.6E-6 T 31-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AF_0673 350c1248a614e71add2003cc9ca08b62 130 Pfam PF13411 MerR HTH family regulatory protein 7 73 9.2E-20 T 31-10-2018 IPR000551 MerR-type HTH domain GO:0003677|GO:0006355 AF_0577 829f4868b06ae5b656be2a09ee2763ad 343 Gene3D G3DSA:3.20.20.70 3 323 2.9E-33 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0577 829f4868b06ae5b656be2a09ee2763ad 343 SUPERFAMILY SSF102114 7 288 3.66E-33 T 31-10-2018 AF_0577 829f4868b06ae5b656be2a09ee2763ad 343 Pfam PF04055 Radical SAM superfamily 9 139 4.1E-10 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_0577 829f4868b06ae5b656be2a09ee2763ad 343 TIGRFAM TIGR04084 rSAM_AF0577: putative peptide-modifying radical SAM enzyme, AF0577 family 8 343 6.1E-103 T 31-10-2018 IPR023819 Peptide-modifying radical SAM enzyme putative, AF0577 AF_0778 397634bbe747891da298b7d6d73c8506 306 PIRSF PIRSF029122 7 306 3.2E-119 T 31-10-2018 IPR010581 Protein of unknown function DUF1152 AF_0778 397634bbe747891da298b7d6d73c8506 306 Pfam PF06626 Protein of unknown function (DUF1152) 16 302 9.0E-101 T 31-10-2018 IPR010581 Protein of unknown function DUF1152 AF_0510 505e152f37460efb98775928f29600f0 289 SUPERFAMILY SSF103481 184 286 1.44E-18 T 31-10-2018 AF_0510 505e152f37460efb98775928f29600f0 289 Pfam PF00892 EamA-like transporter family 6 135 4.1E-26 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AF_0510 505e152f37460efb98775928f29600f0 289 Pfam PF00892 EamA-like transporter family 149 284 1.2E-29 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AF_0510 505e152f37460efb98775928f29600f0 289 SUPERFAMILY SSF103481 38 138 3.14E-14 T 31-10-2018 AF_1348 e7508441e59bdc20506f5528678be50d 85 Gene3D G3DSA:1.10.10.10 2 84 4.6E-13 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1348 e7508441e59bdc20506f5528678be50d 85 SUPERFAMILY SSF46785 5 71 8.17E-6 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0218 fccc6e15811660fb3ba13abcf8cfa8c3 389 Pfam PF02080 TrkA-C domain 123 175 4.2E-9 T 31-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AF_0218 fccc6e15811660fb3ba13abcf8cfa8c3 389 Gene3D G3DSA:3.40.50.720 2 118 5.2E-12 T 31-10-2018 AF_0218 fccc6e15811660fb3ba13abcf8cfa8c3 389 Gene3D G3DSA:3.30.70.1450 119 184 9.0E-8 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AF_0218 fccc6e15811660fb3ba13abcf8cfa8c3 389 Pfam PF02254 TrkA-N domain 3 105 5.0E-13 T 31-10-2018 IPR003148 Regulator of K+ conductance, N-terminal GO:0006813 AF_0218 fccc6e15811660fb3ba13abcf8cfa8c3 389 SUPERFAMILY SSF51735 10 101 9.74E-10 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0218 fccc6e15811660fb3ba13abcf8cfa8c3 389 SUPERFAMILY SSF116726 121 178 3.01E-9 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AF_1409 3bdc04d6c2e0c1aca616ce659a424b75 969 Pfam PF01555 DNA methylase 448 761 7.6E-41 T 31-10-2018 IPR002941 DNA methylase N-4/N-6 GO:0003677|GO:0006306|GO:0008170 AF_1409 3bdc04d6c2e0c1aca616ce659a424b75 969 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 448 460 1.2E-14 T 31-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 AF_1409 3bdc04d6c2e0c1aca616ce659a424b75 969 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 483 502 1.2E-14 T 31-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 AF_1409 3bdc04d6c2e0c1aca616ce659a424b75 969 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 731 745 1.2E-14 T 31-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 AF_1409 3bdc04d6c2e0c1aca616ce659a424b75 969 PRINTS PR00506 D21 class N6 adenine-specific DNA methyltransferase signature 708 730 1.2E-14 T 31-10-2018 IPR002295 N6 adenine-specific DNA methyltransferase, D21 class GO:0003677|GO:0006306|GO:0008170 AF_1409 3bdc04d6c2e0c1aca616ce659a424b75 969 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 451 457 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AF_1409 3bdc04d6c2e0c1aca616ce659a424b75 969 SUPERFAMILY SSF53335 416 779 4.46E-51 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_1241 959d8612aa64ff845d212e4a28dbb47d 418 Gene3D G3DSA:3.90.1150.10 9 413 3.5E-169 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AF_1241 959d8612aa64ff845d212e4a28dbb47d 418 SUPERFAMILY SSF53383 2 417 6.67E-122 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AF_1241 959d8612aa64ff845d212e4a28dbb47d 418 TIGRFAM TIGR00713 hemL: glutamate-1-semialdehyde-2,1-aminomutase 5 417 7.6E-192 T 31-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 AF_1241 959d8612aa64ff845d212e4a28dbb47d 418 Hamap MF_00375 Glutamate-1-semialdehyde 2,1-aminomutase [hemL]. 5 418 93.271 T 31-10-2018 IPR004639 Tetrapyrrole biosynthesis, glutamate-1-semialdehyde aminotransferase GO:0033014|GO:0042286 KEGG: 00860+5.4.3.8|MetaCyc: PWY-5188 AF_1241 959d8612aa64ff845d212e4a28dbb47d 418 Pfam PF00202 Aminotransferase class-III 32 413 3.5E-66 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AF_1241 959d8612aa64ff845d212e4a28dbb47d 418 Gene3D G3DSA:3.40.640.10 68 314 3.5E-169 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AF_1241 959d8612aa64ff845d212e4a28dbb47d 418 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 231 267 - T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AF_0216 624389511aeb235e07676edbb3bd4e77 247 SUPERFAMILY SSF53335 15 245 2.13E-53 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_0216 624389511aeb235e07676edbb3bd4e77 247 Gene3D G3DSA:3.10.330.20 5 56 5.8E-12 T 31-10-2018 AF_0216 624389511aeb235e07676edbb3bd4e77 247 Gene3D G3DSA:3.40.50.150 62 247 1.1E-40 T 31-10-2018 AF_0216 624389511aeb235e07676edbb3bd4e77 247 PIRSF PIRSF017269 1 247 3.5E-67 T 31-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 AF_0216 624389511aeb235e07676edbb3bd4e77 247 Pfam PF08704 tRNA methyltransferase complex GCD14 subunit 75 227 1.2E-12 T 31-10-2018 IPR014816 tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 GO:0016429|GO:0030488|GO:0031515 MetaCyc: PWY-6829 AF_0283 445a043dee59abdde35ac38bae668aad 396 SUPERFAMILY SSF53901 6 232 1.49E-42 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0283 445a043dee59abdde35ac38bae668aad 396 Pfam PF02803 Thiolase, C-terminal domain 261 360 8.0E-6 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 AF_0283 445a043dee59abdde35ac38bae668aad 396 Pfam PF00108 Thiolase, N-terminal domain 8 225 3.7E-22 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AF_0283 445a043dee59abdde35ac38bae668aad 396 Gene3D G3DSA:3.40.47.10 5 394 2.0E-114 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0283 445a043dee59abdde35ac38bae668aad 396 PIRSF PIRSF000429 2 391 3.2E-59 T 31-10-2018 IPR002155 Thiolase GO:0016747 AF_0283 445a043dee59abdde35ac38bae668aad 396 SUPERFAMILY SSF53901 235 390 1.38E-24 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_1438 b69cf4c92938f79adf463bbfb82e9fc2 127 Pfam PF03692 Putative zinc- or iron-chelating domain 11 96 6.1E-20 T 31-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein AF_2153 187f0bdfb43a76afb5f0dff217c5c1e7 208 SUPERFAMILY SSF56281 11 200 9.21E-28 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_2153 187f0bdfb43a76afb5f0dff217c5c1e7 208 Gene3D G3DSA:3.60.15.10 10 206 3.7E-56 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_2153 187f0bdfb43a76afb5f0dff217c5c1e7 208 Pfam PF13483 Beta-lactamase superfamily domain 12 180 1.3E-33 T 31-10-2018 AF_0077 8d4002edd6e15f644211c5df9f0c714c 578 Gene3D G3DSA:3.60.9.10 1 206 2.5E-57 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily AF_0077 8d4002edd6e15f644211c5df9f0c714c 578 Gene3D G3DSA:1.10.569.10 238 431 5.0E-54 T 31-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 AF_0077 8d4002edd6e15f644211c5df9f0c714c 578 SUPERFAMILY SSF56228 2 205 1.44E-58 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily AF_0077 8d4002edd6e15f644211c5df9f0c714c 578 SMART SM00790 1 204 1.5E-94 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 AF_0077 8d4002edd6e15f644211c5df9f0c714c 578 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 218 571 2.3E-60 T 31-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 AF_0077 8d4002edd6e15f644211c5df9f0c714c 578 Gene3D G3DSA:1.10.599.10 237 562 5.0E-54 T 31-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 AF_0077 8d4002edd6e15f644211c5df9f0c714c 578 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 5 202 4.3E-63 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 AF_0077 8d4002edd6e15f644211c5df9f0c714c 578 SUPERFAMILY SSF48310 208 573 5.62E-92 T 31-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 AF_1265 7c322e731b19665da39daff4c5dd485d 231 Gene3D G3DSA:3.60.15.10 1 229 5.0E-79 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_1265 7c322e731b19665da39daff4c5dd485d 231 Pfam PF13483 Beta-lactamase superfamily domain 2 191 5.5E-30 T 31-10-2018 AF_1265 7c322e731b19665da39daff4c5dd485d 231 SUPERFAMILY SSF56281 1 229 1.83E-38 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_1265 7c322e731b19665da39daff4c5dd485d 231 Hamap MF_00457 UPF0173 metal-dependent hydrolase . 1 229 40.722 T 31-10-2018 IPR022877 Protein of unknown funcion UPF0173 AF_1265 7c322e731b19665da39daff4c5dd485d 231 SMART SM00849 7 191 2.2E-11 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_0518 d80bd43493918e22bf18e781430c4409 236 Pfam PF06745 KaiC 4 229 1.2E-24 T 31-10-2018 IPR014774 KaiC-like domain AF_0518 d80bd43493918e22bf18e781430c4409 236 SUPERFAMILY SSF52540 3 229 3.49E-22 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0518 d80bd43493918e22bf18e781430c4409 236 Gene3D G3DSA:3.40.50.300 1 233 2.1E-36 T 31-10-2018 AF_1918 41807dd3430ed0d3db5a62f25d43d142 68 TIGRFAM TIGR00012 L29: ribosomal protein uL29 8 64 1.4E-19 T 31-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1918 41807dd3430ed0d3db5a62f25d43d142 68 SUPERFAMILY SSF46561 4 63 3.79E-15 T 31-10-2018 IPR036049 Ribosomal protein L29/L35 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1918 41807dd3430ed0d3db5a62f25d43d142 68 ProSitePatterns PS00579 Ribosomal protein L29 signature. 43 57 - T 31-10-2018 IPR018254 Ribosomal protein L29, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1918 41807dd3430ed0d3db5a62f25d43d142 68 Gene3D G3DSA:1.10.287.310 2 67 2.1E-21 T 31-10-2018 AF_1918 41807dd3430ed0d3db5a62f25d43d142 68 Pfam PF00831 Ribosomal L29 protein 7 63 1.2E-14 T 31-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1918 41807dd3430ed0d3db5a62f25d43d142 68 Hamap MF_00374 50S ribosomal protein L29 [rpmC]. 4 64 14.517 T 31-10-2018 IPR001854 Ribosomal protein L29/L35 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1140 75564a86b44df98448646ab44214fbe0 439 Pfam PF09847 Membrane protein of 12 TMs 31 435 5.4E-115 T 31-10-2018 IPR018646 Membrane protein of 12 TMs AF_1140 75564a86b44df98448646ab44214fbe0 439 PIRSF PIRSF018875 1 436 5.4E-128 T 31-10-2018 IPR018646 Membrane protein of 12 TMs AF_0328 c41b7cb6d9e4920dc0815e873b60f489 371 Gene3D G3DSA:3.90.550.10 1 218 8.0E-46 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0328 c41b7cb6d9e4920dc0815e873b60f489 371 Pfam PF00535 Glycosyl transferase family 2 3 158 3.3E-31 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AF_0328 c41b7cb6d9e4920dc0815e873b60f489 371 SUPERFAMILY SSF53448 1 233 4.07E-39 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0099 e7bcca505acebe8470de75c14f81977d 154 SUPERFAMILY SSF88723 1 114 9.25E-12 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_0099 e7bcca505acebe8470de75c14f81977d 154 Pfam PF11848 Domain of unknown function (DUF3368) 110 154 7.7E-8 T 31-10-2018 IPR021799 Protein of unknown function DUF3368 AF_2184 17982f6953e53b95030beab3c391a6a7 208 Gene3D G3DSA:3.10.290.10 1 52 1.9E-17 T 31-10-2018 IPR036986 RNA-binding S4 domain superfamily GO:0003723 AF_2184 17982f6953e53b95030beab3c391a6a7 208 SMART SM00363 1 61 5.3E-17 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2184 17982f6953e53b95030beab3c391a6a7 208 Pfam PF01479 S4 domain 1 48 1.9E-15 T 31-10-2018 IPR002942 RNA-binding S4 domain GO:0003723 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2184 17982f6953e53b95030beab3c391a6a7 208 TIGRFAM TIGR00478 tly: TlyA family rRNA methyltransferase/putative hemolysin 2 200 2.7E-66 T 31-10-2018 IPR004538 Haemolysin A /rRNA methyltransferase TlyA GO:0003723 AF_2184 17982f6953e53b95030beab3c391a6a7 208 Pfam PF01728 FtsJ-like methyltransferase 55 148 8.1E-9 T 31-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 AF_2184 17982f6953e53b95030beab3c391a6a7 208 SUPERFAMILY SSF53335 2 188 2.52E-23 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_2184 17982f6953e53b95030beab3c391a6a7 208 Gene3D G3DSA:3.40.50.150 53 203 1.0E-16 T 31-10-2018 AF_1278 07bd9aabb6b91cfbba0a14dbd3761248 407 Gene3D G3DSA:3.30.70.2690 2 97 3.9E-32 T 31-10-2018 AF_1278 07bd9aabb6b91cfbba0a14dbd3761248 407 TIGRFAM TIGR00300 TIGR00300: TIGR00300 family protein 1 403 1.6E-222 T 31-10-2018 IPR005239 Conserved hypothetical protein CHP00300 AF_1278 07bd9aabb6b91cfbba0a14dbd3761248 407 Pfam PF04455 LOR/SDH bifunctional enzyme conserved region 4 102 3.0E-37 T 31-10-2018 IPR007545 LOR/SDH bifunctional enzyme, conserved domain AF_1278 07bd9aabb6b91cfbba0a14dbd3761248 407 Gene3D G3DSA:3.40.50.10690 171 407 5.7E-104 T 31-10-2018 AF_1320 d22eb428181a83b12e8798e3902d0ea5 183 Hamap MF_01510 GMP synthase [glutamine-hydrolyzing] subunit A [guaAA]. 2 183 45.237 T 31-10-2018 IPR023686 GMP synthase (glutamine-hydrolyzing) subunit A GO:0003922 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221 AF_1320 d22eb428181a83b12e8798e3902d0ea5 183 TIGRFAM TIGR00888 guaA_Nterm: GMP synthase (glutamine-hydrolyzing), N-terminal domain 3 182 7.9E-76 T 31-10-2018 IPR004739 GMP synthase, glutamine amidotransferase GO:0003922|GO:0005524|GO:0006177 KEGG: 00230+6.3.5.2|KEGG: 00983+6.3.5.2|MetaCyc: PWY-7221|Reactome: R-HSA-73817 AF_1320 d22eb428181a83b12e8798e3902d0ea5 183 Gene3D G3DSA:3.40.50.880 1 183 1.9E-55 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_1320 d22eb428181a83b12e8798e3902d0ea5 183 SUPERFAMILY SSF52317 1 182 1.19E-51 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_1320 d22eb428181a83b12e8798e3902d0ea5 183 PRINTS PR00096 Glutamine amidotransferase superfamily signature 69 80 1.1E-7 T 31-10-2018 AF_1320 d22eb428181a83b12e8798e3902d0ea5 183 PRINTS PR00096 Glutamine amidotransferase superfamily signature 157 170 1.1E-7 T 31-10-2018 AF_1320 d22eb428181a83b12e8798e3902d0ea5 183 PRINTS PR00096 Glutamine amidotransferase superfamily signature 45 54 1.1E-7 T 31-10-2018 AF_1320 d22eb428181a83b12e8798e3902d0ea5 183 Pfam PF00117 Glutamine amidotransferase class-I 5 178 1.9E-40 T 31-10-2018 IPR017926 Glutamine amidotransferase AF_1320 d22eb428181a83b12e8798e3902d0ea5 183 PRINTS PR00097 Anthranilate synthase component II signature 157 170 2.6E-8 T 31-10-2018 AF_1320 d22eb428181a83b12e8798e3902d0ea5 183 PRINTS PR00097 Anthranilate synthase component II signature 3 17 2.6E-8 T 31-10-2018 AF_1320 d22eb428181a83b12e8798e3902d0ea5 183 PRINTS PR00097 Anthranilate synthase component II signature 69 80 2.6E-8 T 31-10-2018 AF_1320 d22eb428181a83b12e8798e3902d0ea5 183 PRINTS PR00097 Anthranilate synthase component II signature 45 54 2.6E-8 T 31-10-2018 AF_1391 38345eec58dc768ec55814cf1822bcae 425 Pfam PF13458 Periplasmic binding protein 37 404 1.9E-36 T 31-10-2018 IPR028081 Leucine-binding protein domain AF_1391 38345eec58dc768ec55814cf1822bcae 425 Gene3D G3DSA:3.40.50.2300 162 304 1.0E-49 T 31-10-2018 AF_1391 38345eec58dc768ec55814cf1822bcae 425 SUPERFAMILY SSF53822 37 411 6.06E-54 T 31-10-2018 IPR028082 Periplasmic binding protein-like I AF_1391 38345eec58dc768ec55814cf1822bcae 425 Gene3D G3DSA:3.40.50.2300 44 367 1.0E-49 T 31-10-2018 AF_1650 574e7c8c74a2d3d471f2c5417d42b5b2 399 Gene3D G3DSA:3.40.50.740 236 397 5.3E-7 T 31-10-2018 AF_1650 574e7c8c74a2d3d471f2c5417d42b5b2 399 PIRSF PIRSF005646 1 399 1.2E-149 T 31-10-2018 IPR016457 Formylmethanofuran dehydrogenase, subunit B GO:0015948|GO:0018493 KEGG: 00680+1.2.7.12|MetaCyc: PWY-5209|MetaCyc: PWY-7784 AF_1650 574e7c8c74a2d3d471f2c5417d42b5b2 399 Gene3D G3DSA:3.40.228.10 105 215 6.3E-7 T 31-10-2018 AF_1650 574e7c8c74a2d3d471f2c5417d42b5b2 399 SUPERFAMILY SSF53706 4 380 1.19E-30 T 31-10-2018 AF_1650 574e7c8c74a2d3d471f2c5417d42b5b2 399 TIGRFAM TIGR03129 one_C_dehyd_B: formylmethanofuran dehydrogenase subunit B 3 398 2.4E-140 T 31-10-2018 IPR016457 Formylmethanofuran dehydrogenase, subunit B GO:0015948|GO:0018493 KEGG: 00680+1.2.7.12|MetaCyc: PWY-5209|MetaCyc: PWY-7784 AF_2235 a95ae51b2d14c579f4602124471ec5e1 329 Pfam PF04015 Domain of unknown function (DUF362) 71 271 2.1E-39 T 31-10-2018 IPR007160 Domain of unknown function DUF362 AF_2324 32df74d1ece1df041d58a61082eed8b7 437 SUPERFAMILY SSF53335 136 435 7.5E-56 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_2324 32df74d1ece1df041d58a61082eed8b7 437 Gene3D G3DSA:3.40.50.150 144 435 3.7E-67 T 31-10-2018 AF_2324 32df74d1ece1df041d58a61082eed8b7 437 SUPERFAMILY SSF48013 13 151 1.7E-22 T 31-10-2018 IPR035926 NusB-like superfamily AF_2324 32df74d1ece1df041d58a61082eed8b7 437 Gene3D G3DSA:1.10.940.10 11 143 6.5E-17 T 31-10-2018 IPR035926 NusB-like superfamily AF_2324 32df74d1ece1df041d58a61082eed8b7 437 Pfam PF01189 16S rRNA methyltransferase RsmB/F 244 433 2.3E-40 T 31-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 AF_2324 32df74d1ece1df041d58a61082eed8b7 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 364 380 7.8E-20 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AF_2324 32df74d1ece1df041d58a61082eed8b7 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 225 239 7.8E-20 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AF_2324 32df74d1ece1df041d58a61082eed8b7 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 317 329 7.8E-20 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AF_2324 32df74d1ece1df041d58a61082eed8b7 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 418 435 7.8E-20 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AF_2324 32df74d1ece1df041d58a61082eed8b7 437 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 254 264 7.8E-20 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AF_2324 32df74d1ece1df041d58a61082eed8b7 437 Pfam PF01029 NusB family 13 129 1.3E-15 T 31-10-2018 IPR006027 NusB/RsmB/TIM44 GO:0003723|GO:0006355 AF_1122 ddd0f1c9eb8915e6e80698b023605a6f 650 Gene3D G3DSA:1.10.1040.10 295 381 2.1E-24 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AF_1122 ddd0f1c9eb8915e6e80698b023605a6f 650 Gene3D G3DSA:1.10.12.10 593 650 3.7E-13 T 31-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AF_1122 ddd0f1c9eb8915e6e80698b023605a6f 650 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 183 276 1.2E-26 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_1122 ddd0f1c9eb8915e6e80698b023605a6f 650 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 298 388 1.0E-19 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_1122 ddd0f1c9eb8915e6e80698b023605a6f 650 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2 180 3.0E-64 T 31-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_1122 ddd0f1c9eb8915e6e80698b023605a6f 650 Gene3D G3DSA:1.10.1040.10 185 294 6.3E-29 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AF_1122 ddd0f1c9eb8915e6e80698b023605a6f 650 Gene3D G3DSA:3.90.226.10 382 590 1.7E-53 T 31-10-2018 AF_1122 ddd0f1c9eb8915e6e80698b023605a6f 650 SUPERFAMILY SSF52096 388 650 2.49E-70 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AF_1122 ddd0f1c9eb8915e6e80698b023605a6f 650 Pfam PF00378 Enoyl-CoA hydratase/isomerase 403 649 5.1E-51 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AF_1122 ddd0f1c9eb8915e6e80698b023605a6f 650 Gene3D G3DSA:3.40.50.720 1 184 4.5E-67 T 31-10-2018 AF_1122 ddd0f1c9eb8915e6e80698b023605a6f 650 SUPERFAMILY SSF51735 2 178 2.69E-55 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1122 ddd0f1c9eb8915e6e80698b023605a6f 650 SUPERFAMILY SSF48179 298 390 5.87E-22 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_1122 ddd0f1c9eb8915e6e80698b023605a6f 650 SUPERFAMILY SSF48179 182 278 1.19E-26 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_1689 a3254788b456ab913e8af5b097fc5ab5 73 ProDom PD188822 UPF0330 AF1997 ST1125.1 AF1689 AF1478 C1_0043 PYRAB04040 PF1222 MM2475 MA1514 1 54 3.0E-23 T 31-10-2018 IPR003847 Putative antitoxin AF_1689 a3254788b456ab913e8af5b097fc5ab5 73 Pfam PF02697 Putative antitoxin 2 67 6.5E-22 T 31-10-2018 IPR003847 Putative antitoxin AF_1689 a3254788b456ab913e8af5b097fc5ab5 73 Hamap MF_00794 Putative antitoxin . 1 71 16.098 T 31-10-2018 IPR003847 Putative antitoxin AF_1862 a11c408f4faf3f9feb19bca300b65152 155 Pfam PF09701 CRISPR-associated protein (Cas_Cmr5) 6 150 1.9E-35 T 31-10-2018 IPR010160 CRISPR-associated protein, Cmr5 AF_1862 a11c408f4faf3f9feb19bca300b65152 155 Gene3D G3DSA:1.10.520.30 1 155 3.7E-57 T 31-10-2018 IPR023101 AF1862-like domain superfamily AF_1862 a11c408f4faf3f9feb19bca300b65152 155 SUPERFAMILY SSF158568 4 152 9.55E-43 T 31-10-2018 IPR023101 AF1862-like domain superfamily AF_1862 a11c408f4faf3f9feb19bca300b65152 155 TIGRFAM TIGR01881 cas_Cmr5: CRISPR type III-B/RAMP module-associated protein Cmr5 4 154 4.1E-52 T 31-10-2018 IPR010160 CRISPR-associated protein, Cmr5 AF_1416 77c897d84bd6fff31ad080f16f274074 153 Gene3D G3DSA:3.40.50.960 1 153 1.6E-54 T 31-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AF_1416 77c897d84bd6fff31ad080f16f274074 153 SUPERFAMILY SSF52121 1 134 3.4E-27 T 31-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AF_1416 77c897d84bd6fff31ad080f16f274074 153 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 2 127 2.8E-12 T 31-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AF_1416 77c897d84bd6fff31ad080f16f274074 153 TIGRFAM TIGR01506 ribC_arch: riboflavin synthase 2 151 5.0E-85 T 31-10-2018 IPR006399 Riboflavin synthase, archaeal GO:0004746|GO:0009231 KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AF_1416 77c897d84bd6fff31ad080f16f274074 153 PIRSF PIRSF015750 1 153 1.6E-76 T 31-10-2018 IPR006399 Riboflavin synthase, archaeal GO:0004746|GO:0009231 KEGG: 00740+2.5.1.9|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AF_0208 1fa6517fa5acbe70be5179c2134a04cc 481 SUPERFAMILY SSF55890 280 320 8.76E-7 T 31-10-2018 IPR016120 Signal transduction histidine kinase, sporulation regulator SpoOB GO:0000155|GO:0000160|GO:0016772 AF_0208 1fa6517fa5acbe70be5179c2134a04cc 481 Gene3D G3DSA:1.10.287.130 255 324 4.3E-8 T 31-10-2018 AF_0208 1fa6517fa5acbe70be5179c2134a04cc 481 Gene3D G3DSA:3.30.565.10 325 479 3.2E-31 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_0208 1fa6517fa5acbe70be5179c2134a04cc 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 405 419 5.5E-11 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_0208 1fa6517fa5acbe70be5179c2134a04cc 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 435 453 5.5E-11 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_0208 1fa6517fa5acbe70be5179c2134a04cc 481 PRINTS PR00344 Bacterial sensor protein C-terminal signature 459 472 5.5E-11 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_0208 1fa6517fa5acbe70be5179c2134a04cc 481 SMART SM00387 369 475 2.2E-30 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_0208 1fa6517fa5acbe70be5179c2134a04cc 481 Pfam PF14689 Sensor_kinase_SpoOB-type, alpha-helical domain 265 321 1.0E-16 T 31-10-2018 IPR039506 SpoOB, alpha-helical domain AF_0208 1fa6517fa5acbe70be5179c2134a04cc 481 SUPERFAMILY SSF55874 339 471 2.62E-30 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_0208 1fa6517fa5acbe70be5179c2134a04cc 481 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 373 473 4.3E-22 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_1454 f78603b2a078c6493264447beebdf529 286 Pfam PF01428 AN1-like Zinc finger 224 260 7.1E-10 T 31-10-2018 IPR000058 Zinc finger, AN1-type GO:0008270 AF_1454 f78603b2a078c6493264447beebdf529 286 SMART SM00154 224 261 1.1E-15 T 31-10-2018 IPR000058 Zinc finger, AN1-type GO:0008270 AF_1454 f78603b2a078c6493264447beebdf529 286 SUPERFAMILY SSF118310 217 274 3.92E-15 T 31-10-2018 IPR035896 AN1-like Zinc finger AF_1454 f78603b2a078c6493264447beebdf529 286 Gene3D G3DSA:4.10.1110.10 205 268 7.3E-11 T 31-10-2018 IPR035896 AN1-like Zinc finger AF_1671 159fbcecfe5fbf730f0daab646db5d62 433 Gene3D G3DSA:3.40.50.12780 2 325 1.2E-126 T 31-10-2018 AF_1671 159fbcecfe5fbf730f0daab646db5d62 433 Pfam PF14535 AMP-binding enzyme C-terminal domain 334 431 8.7E-32 T 31-10-2018 IPR028154 AMP-dependent ligase, C-terminal AF_1671 159fbcecfe5fbf730f0daab646db5d62 433 Pfam PF00501 AMP-binding enzyme 90 333 9.7E-19 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_1671 159fbcecfe5fbf730f0daab646db5d62 433 PIRSF PIRSF006444 1 433 6.4E-207 T 31-10-2018 IPR011880 Phenylacetate-CoA ligase GO:0010124|GO:0047475 KEGG: 00360+6.2.1.30|MetaCyc: PWY-1341|MetaCyc: PWY-6318|MetaCyc: PWY-7716 AF_1671 159fbcecfe5fbf730f0daab646db5d62 433 SUPERFAMILY SSF56801 30 388 8.9E-67 T 31-10-2018 AF_1671 159fbcecfe5fbf730f0daab646db5d62 433 Gene3D G3DSA:3.30.300.30 326 433 2.0E-34 T 31-10-2018 AF_2268 42732983741cbf2d6fb1c4475539ecc5 240 SUPERFAMILY SSF160104 14 232 5.75E-32 T 31-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 AF_2268 42732983741cbf2d6fb1c4475539ecc5 240 Gene3D G3DSA:2.40.400.10 2 240 7.4E-44 T 31-10-2018 IPR023375 Acetoacetate decarboxylase domain superfamily KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 AF_2268 42732983741cbf2d6fb1c4475539ecc5 240 Pfam PF06314 Acetoacetate decarboxylase (ADC) 6 238 9.2E-41 T 31-10-2018 IPR010451 Acetoacetate decarboxylase GO:0016829 KEGG: 00072+4.1.1.4|KEGG: 00640+4.1.1.4|MetaCyc: PWY-5451|MetaCyc: PWY-6588|MetaCyc: PWY-6876|MetaCyc: PWY-7466 AF_2106 a0ac312b71c866c661604399f77be3b2 233 Hamap MF_01285 Riboflavin kinase [ribK]. 105 231 27.797 T 31-10-2018 IPR023470 Riboflavin kinase, archaeal GO:0008531|GO:0009231 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 AF_2106 a0ac312b71c866c661604399f77be3b2 233 SMART SM00419 30 82 6.2E-9 T 31-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AF_2106 a0ac312b71c866c661604399f77be3b2 233 Gene3D G3DSA:2.40.30.30 102 233 6.0E-54 T 31-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 AF_2106 a0ac312b71c866c661604399f77be3b2 233 Gene3D G3DSA:1.10.10.10 17 100 3.9E-20 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_2106 a0ac312b71c866c661604399f77be3b2 233 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 36 52 5.6E-5 T 31-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AF_2106 a0ac312b71c866c661604399f77be3b2 233 PRINTS PR00034 CRP bacterial regulatory protein HTH signature 52 67 5.6E-5 T 31-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AF_2106 a0ac312b71c866c661604399f77be3b2 233 Pfam PF13412 Winged helix-turn-helix DNA-binding 38 67 7.6E-7 T 31-10-2018 AF_2106 a0ac312b71c866c661604399f77be3b2 233 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 37 48 5.6E-5 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_2106 a0ac312b71c866c661604399f77be3b2 233 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 48 67 5.6E-5 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_2106 a0ac312b71c866c661604399f77be3b2 233 SUPERFAMILY SSF82114 104 231 2.06E-49 T 31-10-2018 IPR023465 Riboflavin kinase domain superfamily GO:0008531|GO:0009231 Reactome: R-HSA-196843 AF_2106 a0ac312b71c866c661604399f77be3b2 233 SUPERFAMILY SSF46785 23 95 1.49E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_2106 a0ac312b71c866c661604399f77be3b2 233 Pfam PF01982 Domain of unknown function DUF120 111 231 7.3E-49 T 31-10-2018 IPR023602 Riboflavin kinase domain, CTP-dependent GO:0016773 KEGG: 00740+2.7.1.161|MetaCyc: PWY-6167 AF_0955 faaa7d36d09ed5797688334cfdd304e1 359 Pfam PF13374 Tetratricopeptide repeat 44 75 4.2E-4 T 31-10-2018 AF_0955 faaa7d36d09ed5797688334cfdd304e1 359 Pfam PF13374 Tetratricopeptide repeat 85 112 0.0067 T 31-10-2018 AF_0955 faaa7d36d09ed5797688334cfdd304e1 359 SMART SM00028 84 117 0.019 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AF_0955 faaa7d36d09ed5797688334cfdd304e1 359 SMART SM00028 39 72 0.13 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AF_0955 faaa7d36d09ed5797688334cfdd304e1 359 SMART SM00028 163 196 38.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AF_0955 faaa7d36d09ed5797688334cfdd304e1 359 SMART SM00028 123 156 160.0 T 31-10-2018 IPR019734 Tetratricopeptide repeat GO:0005515 AF_0955 faaa7d36d09ed5797688334cfdd304e1 359 SUPERFAMILY SSF48452 85 208 5.96E-14 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AF_0955 faaa7d36d09ed5797688334cfdd304e1 359 Pfam PF13424 Tetratricopeptide repeat 122 194 1.5E-7 T 31-10-2018 AF_0955 faaa7d36d09ed5797688334cfdd304e1 359 Gene3D G3DSA:1.25.40.10 124 215 6.2E-10 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AF_0955 faaa7d36d09ed5797688334cfdd304e1 359 Gene3D G3DSA:1.25.40.10 2 123 9.1E-14 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AF_1293 5ce42f10919b924a64bf305bda0732de 384 PIRSF PIRSF016578 3 383 1.7E-15 T 31-10-2018 AF_1293 5ce42f10919b924a64bf305bda0732de 384 Gene3D G3DSA:1.20.140.10 236 383 7.2E-58 T 31-10-2018 AF_1293 5ce42f10919b924a64bf305bda0732de 384 SUPERFAMILY SSF56645 3 241 6.68E-85 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AF_1293 5ce42f10919b924a64bf305bda0732de 384 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 378 7.5E-55 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AF_1293 5ce42f10919b924a64bf305bda0732de 384 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 9 118 2.4E-35 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AF_1293 5ce42f10919b924a64bf305bda0732de 384 SUPERFAMILY SSF47203 228 382 1.34E-62 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AF_1293 5ce42f10919b924a64bf305bda0732de 384 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 123 218 1.6E-24 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AF_1293 5ce42f10919b924a64bf305bda0732de 384 Gene3D G3DSA:2.40.110.10 123 235 1.4E-41 T 31-10-2018 AF_1293 5ce42f10919b924a64bf305bda0732de 384 Gene3D G3DSA:1.10.540.10 1 118 7.3E-42 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AF_1293 5ce42f10919b924a64bf305bda0732de 384 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 31-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AF_0371 de365c3eda7bd626092e292d1d0be140 198 SMART SM00478 46 193 7.7E-17 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AF_0371 de365c3eda7bd626092e292d1d0be140 198 Gene3D G3DSA:1.10.340.30 34 134 1.9E-49 T 31-10-2018 AF_0371 de365c3eda7bd626092e292d1d0be140 198 SUPERFAMILY SSF48150 31 179 7.33E-20 T 31-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AF_0371 de365c3eda7bd626092e292d1d0be140 198 Hamap MF_00241 Probable N-glycosylase/DNA lyase [ogg]. 6 198 29.336 T 31-10-2018 IPR012092 8-oxoguanine DNA glycosylase/DNA lyase, thermostable GO:0003906|GO:0006281|GO:0016799 AF_0371 de365c3eda7bd626092e292d1d0be140 198 PIRSF PIRSF005954 1 198 5.4E-74 T 31-10-2018 IPR012092 8-oxoguanine DNA glycosylase/DNA lyase, thermostable GO:0003906|GO:0006281|GO:0016799 AF_0371 de365c3eda7bd626092e292d1d0be140 198 Gene3D G3DSA:1.10.1670.10 135 198 1.9E-49 T 31-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AF_1144 d912402e21f0d97b398d2775a351df8e 451 Gene3D G3DSA:1.20.1720.10 8 233 5.3E-43 T 31-10-2018 AF_1144 d912402e21f0d97b398d2775a351df8e 451 Pfam PF07690 Major Facilitator Superfamily 14 395 5.0E-53 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AF_1144 d912402e21f0d97b398d2775a351df8e 451 SUPERFAMILY SSF103473 6 447 2.49E-66 T 31-10-2018 IPR036259 MFS transporter superfamily AF_1144 d912402e21f0d97b398d2775a351df8e 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 288 312 7.6E-7 T 31-10-2018 AF_1144 d912402e21f0d97b398d2775a351df8e 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 218 236 7.6E-7 T 31-10-2018 AF_1144 d912402e21f0d97b398d2775a351df8e 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 131 155 7.6E-7 T 31-10-2018 AF_1144 d912402e21f0d97b398d2775a351df8e 451 PRINTS PR01036 Tetracycline resistance protein TetB signature 70 92 7.6E-7 T 31-10-2018 AF_1144 d912402e21f0d97b398d2775a351df8e 451 Gene3D G3DSA:1.20.1250.20 241 447 9.0E-24 T 31-10-2018 AF_2319 2ed09918bd47a7199fb997184121a6ee 194 Pfam PF00827 Ribosomal L15 3 188 2.4E-81 T 31-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2319 2ed09918bd47a7199fb997184121a6ee 194 Gene3D G3DSA:3.40.1120.10 1 192 4.3E-81 T 31-10-2018 IPR024794 Ribosomal protein L15e core domain superfamily GO:0003735|GO:0005840 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2319 2ed09918bd47a7199fb997184121a6ee 194 ProSitePatterns PS01194 Ribosomal protein L15e signature. 47 70 - T 31-10-2018 IPR020925 Ribosomal protein L15e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2319 2ed09918bd47a7199fb997184121a6ee 194 SUPERFAMILY SSF54189 2 193 2.49E-80 T 31-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_2319 2ed09918bd47a7199fb997184121a6ee 194 SMART SM01384 3 190 4.6E-117 T 31-10-2018 IPR000439 Ribosomal protein L15e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2319 2ed09918bd47a7199fb997184121a6ee 194 Hamap MF_00256 50S ribosomal protein L15e [rpl15e]. 2 192 42.938 T 31-10-2018 IPR020926 Ribosomal protein L15e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1127 fe0e91c78f0c1f1534d274d64130875c 92 ProSitePatterns PS00475 Ribosomal protein L15 signature. 39 69 - T 31-10-2018 IPR001196 Ribosomal protein L15, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1127 fe0e91c78f0c1f1534d274d64130875c 92 Pfam PF17135 Ribosomal protein 60S L18 and 50S L18e 3 91 5.3E-11 T 31-10-2018 IPR021131 Ribosomal protein L18e/L15P AF_1127 fe0e91c78f0c1f1534d274d64130875c 92 Gene3D G3DSA:3.100.10.10 1 92 4.7E-34 T 31-10-2018 AF_1127 fe0e91c78f0c1f1534d274d64130875c 92 SUPERFAMILY SSF52080 2 91 3.14E-26 T 31-10-2018 IPR036227 Ribosomal L18e/L15P superfamily AF_1973 431d79b3105f657365801b4bc630247c 336 SUPERFAMILY SSF53335 86 335 9.98E-66 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_1973 431d79b3105f657365801b4bc630247c 336 Gene3D G3DSA:3.30.300.110 69 147 3.2E-16 T 31-10-2018 AF_1973 431d79b3105f657365801b4bc630247c 336 Gene3D G3DSA:3.40.50.150 150 336 5.1E-57 T 31-10-2018 AF_1973 431d79b3105f657365801b4bc630247c 336 Pfam PF02475 Met-10+ like-protein 91 284 1.9E-78 T 31-10-2018 IPR030382 SAM-dependent methyltransferase TRM5/TYW2-type Reactome: R-HSA-6782861 AF_1973 431d79b3105f657365801b4bc630247c 336 Hamap MF_01922 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase [taw2]. 88 336 43.582 T 31-10-2018 IPR030867 tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase GO:0006400|GO:0016765 MetaCyc: PWY-7286 AF_0446 38ba2390c7d9e713420b45df4f151a1f 126 Pfam PF03168 Late embryogenesis abundant protein 23 114 9.9E-12 T 31-10-2018 IPR004864 Late embryogenesis abundant protein, LEA_2 subgroup AF_0446 38ba2390c7d9e713420b45df4f151a1f 126 SUPERFAMILY SSF117070 13 114 1.96E-11 T 31-10-2018 AF_0446 38ba2390c7d9e713420b45df4f151a1f 126 Gene3D G3DSA:2.60.40.10 1 126 2.5E-49 T 31-10-2018 IPR013783 Immunoglobulin-like fold AF_0446 38ba2390c7d9e713420b45df4f151a1f 126 SMART SM00769 1 119 2.4E-34 T 31-10-2018 IPR013990 Water stress and hypersensitive response domain GO:0009269 AF_1281 cd50e3f01b2c38aba66f11f513315392 168 TIGRFAM TIGR01382 PfpI: intracellular protease, PfpI family 3 166 1.9E-56 T 31-10-2018 IPR006286 Deglycase PfpI AF_1281 cd50e3f01b2c38aba66f11f513315392 168 Pfam PF01965 DJ-1/PfpI family 1 163 4.0E-58 T 31-10-2018 IPR002818 DJ-1/PfpI Reactome: R-HSA-3899300 AF_1281 cd50e3f01b2c38aba66f11f513315392 168 SUPERFAMILY SSF52317 1 165 8.6E-48 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_1281 cd50e3f01b2c38aba66f11f513315392 168 Gene3D G3DSA:3.40.50.880 1 167 2.1E-49 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_2286 f655addc66dfdc0c2cc1bd68b5fe0a23 326 SUPERFAMILY SSF48576 14 325 9.93E-89 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily AF_2286 f655addc66dfdc0c2cc1bd68b5fe0a23 326 Pfam PF00348 Polyprenyl synthetase 38 255 6.5E-67 T 31-10-2018 IPR000092 Polyprenyl synthetase GO:0008299 AF_2286 f655addc66dfdc0c2cc1bd68b5fe0a23 326 Gene3D G3DSA:1.10.600.10 7 326 3.8E-104 T 31-10-2018 IPR008949 Isoprenoid synthase domain superfamily AF_2286 f655addc66dfdc0c2cc1bd68b5fe0a23 326 ProSitePatterns PS00723 Polyprenyl synthases signature 1. 87 101 - T 31-10-2018 IPR033749 Polyprenyl synthetase, conserved site AF_1838 38e949e0c45069a1bbd64f94be46e1e5 236 SUPERFAMILY SSF51735 3 116 1.65E-24 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1838 38e949e0c45069a1bbd64f94be46e1e5 236 Gene3D G3DSA:3.30.360.10 111 211 8.3E-95 T 31-10-2018 AF_1838 38e949e0c45069a1bbd64f94be46e1e5 236 TIGRFAM TIGR03855 NAD_NadX: aspartate dehydrogenase 24 236 3.3E-92 T 31-10-2018 IPR022487 L-aspartate dehydrogenase, archaeal GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 AF_1838 38e949e0c45069a1bbd64f94be46e1e5 236 SUPERFAMILY SSF55347 111 206 1.31E-23 T 31-10-2018 AF_1838 38e949e0c45069a1bbd64f94be46e1e5 236 Pfam PF01958 Domain of unknown function DUF108 142 223 5.3E-30 T 31-10-2018 IPR002811 Aspartate dehydrogenase GO:0006742|GO:0016491|GO:0019363|GO:0055114 KEGG: 00760+1.4.1.21 AF_1838 38e949e0c45069a1bbd64f94be46e1e5 236 PIRSF PIRSF005227 1 236 5.6E-87 T 31-10-2018 IPR011182 L-aspartate dehydrogenase GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 AF_1838 38e949e0c45069a1bbd64f94be46e1e5 236 Hamap MF_01265 Probable L-aspartate dehydrogenase [nadX]. 1 236 31.584 T 31-10-2018 IPR020626 L-aspartate dehydrogenase, prokaryotic GO:0009435|GO:0033735|GO:0055114 KEGG: 00760+1.4.1.21 AF_1838 38e949e0c45069a1bbd64f94be46e1e5 236 Pfam PF03447 Homoserine dehydrogenase, NAD binding domain 7 107 4.0E-14 T 31-10-2018 IPR005106 Aspartate/homoserine dehydrogenase, NAD-binding GO:0016491|GO:0050661|GO:0055114 AF_1838 38e949e0c45069a1bbd64f94be46e1e5 236 Gene3D G3DSA:3.40.50.720 3 229 8.3E-95 T 31-10-2018 AF_0814 f02f6310e1cc9d5b0023520b6adea67c 165 Pfam PF03266 NTPase 2 159 5.4E-53 T 31-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 AF_0814 f02f6310e1cc9d5b0023520b6adea67c 165 Hamap MF_00796 Nucleoside-triphosphatase . 1 163 26.685 T 31-10-2018 IPR004948 Nucleoside-triphosphatase, THEP1 type GO:0098519 KEGG: 00230+3.6.1.15|KEGG: 00730+3.6.1.15|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7198|MetaCyc: PWY-7210 AF_0814 f02f6310e1cc9d5b0023520b6adea67c 165 SUPERFAMILY SSF52540 3 163 6.25E-17 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0814 f02f6310e1cc9d5b0023520b6adea67c 165 SMART SM00382 1 148 2.0E-4 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0814 f02f6310e1cc9d5b0023520b6adea67c 165 Gene3D G3DSA:3.40.50.300 1 164 1.7E-45 T 31-10-2018 AF_0966 d715cb37c4675e23981a15d84e959547 176 Gene3D G3DSA:1.10.12.20 21 92 9.3E-26 T 31-10-2018 AF_0966 d715cb37c4675e23981a15d84e959547 176 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 53 82 5.7E-8 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AF_0966 d715cb37c4675e23981a15d84e959547 176 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 89 156 1.3E-14 T 31-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AF_0966 d715cb37c4675e23981a15d84e959547 176 SUPERFAMILY SSF50249 27 160 1.2E-34 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_1709 20fbcf1aa4907e20c3934711ae9be101 304 Gene3D G3DSA:1.20.120.330 45 191 3.2E-12 T 31-10-2018 AF_1709 20fbcf1aa4907e20c3934711ae9be101 304 SMART SM00748 56 138 0.0051 T 31-10-2018 IPR007842 HEPN domain AF_1709 20fbcf1aa4907e20c3934711ae9be101 304 Pfam PF05168 HEPN domain 53 103 1.4E-9 T 31-10-2018 IPR007842 HEPN domain AF_1709 20fbcf1aa4907e20c3934711ae9be101 304 SUPERFAMILY SSF81593 55 103 2.79E-8 T 31-10-2018 AF_0775 e2c28cea20f812dee93946473cebc67e 253 Gene3D G3DSA:3.40.50.300 1 211 1.3E-37 T 31-10-2018 AF_0775 e2c28cea20f812dee93946473cebc67e 253 SUPERFAMILY SSF52540 2 207 6.15E-32 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0775 e2c28cea20f812dee93946473cebc67e 253 Pfam PF06745 KaiC 5 210 1.5E-32 T 31-10-2018 IPR014774 KaiC-like domain AF_1159 740c7c1f7f88569426286436be2f0d63 676 Gene3D G3DSA:1.20.1460.20 44 270 1.4E-14 T 31-10-2018 AF_1159 740c7c1f7f88569426286436be2f0d63 676 Gene3D G3DSA:3.30.70.2170 7 291 1.4E-14 T 31-10-2018 AF_1159 740c7c1f7f88569426286436be2f0d63 676 Gene3D G3DSA:3.30.70.2750 125 205 1.4E-14 T 31-10-2018 AF_1159 740c7c1f7f88569426286436be2f0d63 676 Pfam PF01496 V-type ATPase 116kDa subunit family 160 406 8.2E-21 T 31-10-2018 IPR002490 V-type ATPase, V0 complex, 116kDa subunit family GO:0015078|GO:0015991|GO:0033179 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AF_1063 e1578a2b59da2edf0f4ab3a5f5e088bb 134 Pfam PF00072 Response regulator receiver domain 20 125 3.4E-22 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_1063 e1578a2b59da2edf0f4ab3a5f5e088bb 134 SMART SM00448 18 126 1.3E-26 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_1063 e1578a2b59da2edf0f4ab3a5f5e088bb 134 SUPERFAMILY SSF52172 17 131 3.7E-32 T 31-10-2018 IPR011006 CheY-like superfamily AF_1063 e1578a2b59da2edf0f4ab3a5f5e088bb 134 Gene3D G3DSA:3.40.50.2300 15 134 8.5E-31 T 31-10-2018 AF_1469 4a8b91df7bfcdef7c74bebee5b7fcef1 226 SUPERFAMILY SSF52540 3 224 1.46E-79 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1469 4a8b91df7bfcdef7c74bebee5b7fcef1 226 Pfam PF00005 ABC transporter 23 171 1.2E-37 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_1469 4a8b91df7bfcdef7c74bebee5b7fcef1 226 ProSitePatterns PS00211 ABC transporters family signature. 144 158 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_1469 4a8b91df7bfcdef7c74bebee5b7fcef1 226 SMART SM00382 32 220 1.2E-19 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1469 4a8b91df7bfcdef7c74bebee5b7fcef1 226 Gene3D G3DSA:3.40.50.300 1 225 4.2E-78 T 31-10-2018 AF_0625 249ea7f6f96fc30097bd30c90ce576a7 278 Hamap MF_00562 D-aminoacyl-tRNA deacylase [dtdA]. 1 267 35.398 T 31-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 AF_0625 249ea7f6f96fc30097bd30c90ce576a7 278 Pfam PF04414 D-aminoacyl-tRNA deacylase 66 265 7.9E-70 T 31-10-2018 IPR007508 D-aminoacyl-tRNA deacylase DtdA GO:0016788|GO:0051499 AF_0625 249ea7f6f96fc30097bd30c90ce576a7 278 Gene3D G3DSA:3.40.630.50 1 182 1.5E-69 T 31-10-2018 AF_0625 249ea7f6f96fc30097bd30c90ce576a7 278 Gene3D G3DSA:3.40.50.10700 183 278 2.4E-36 T 31-10-2018 AF_0625 249ea7f6f96fc30097bd30c90ce576a7 278 SUPERFAMILY SSF142535 1 275 5.23E-86 T 31-10-2018 AF_0625 249ea7f6f96fc30097bd30c90ce576a7 278 PIRSF PIRSF016210 1 268 2.1E-91 T 31-10-2018 IPR018033 D-aminoacyl-tRNA deacylase, archaea GO:0016788|GO:0019478|GO:0051499 AF_1395 c7597819b6e5faa0587ba6aa1bb298bd 323 Hamap MF_01111 UPF0200 protein . 7 186 33.903 T 31-10-2018 IPR022970 Nucleoside triphosphate hydrolase-related AF_1395 c7597819b6e5faa0587ba6aa1bb298bd 323 Hamap MF_01112 UPF0201 protein . 189 315 23.687 T 31-10-2018 IPR002739 Uncharacterised protein family UPF0201 AF_1395 c7597819b6e5faa0587ba6aa1bb298bd 323 Gene3D G3DSA:3.40.50.300 5 184 1.8E-49 T 31-10-2018 AF_1395 c7597819b6e5faa0587ba6aa1bb298bd 323 Gene3D G3DSA:3.30.1440.10 185 313 4.0E-46 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1395 c7597819b6e5faa0587ba6aa1bb298bd 323 SUPERFAMILY SSF52540 5 187 1.6E-20 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1395 c7597819b6e5faa0587ba6aa1bb298bd 323 SUPERFAMILY SSF55282 190 321 1.77E-36 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1395 c7597819b6e5faa0587ba6aa1bb298bd 323 Pfam PF01877 RNA binding 190 294 7.7E-13 T 31-10-2018 IPR002739 Uncharacterised protein family UPF0201 AF_1395 c7597819b6e5faa0587ba6aa1bb298bd 323 Pfam PF13207 AAA domain 11 143 1.0E-19 T 31-10-2018 AF_1005 2b6b4778b21977f612adbf27e7c538d7 366 PRINTS PR00164 ABC-2 type transport system membrane protein signature 246 270 4.1E-7 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AF_1005 2b6b4778b21977f612adbf27e7c538d7 366 PRINTS PR00164 ABC-2 type transport system membrane protein signature 303 322 4.1E-7 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AF_1005 2b6b4778b21977f612adbf27e7c538d7 366 PRINTS PR00164 ABC-2 type transport system membrane protein signature 167 189 4.1E-7 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AF_1005 2b6b4778b21977f612adbf27e7c538d7 366 PRINTS PR00164 ABC-2 type transport system membrane protein signature 283 302 4.1E-7 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AF_1005 2b6b4778b21977f612adbf27e7c538d7 366 Pfam PF12698 ABC-2 family transporter protein 21 353 2.5E-42 T 31-10-2018 AF_1476 6c36949a06930d44501d4d8470a4100f 177 Gene3D G3DSA:3.10.180.10 48 175 1.1E-37 T 31-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AF_1476 6c36949a06930d44501d4d8470a4100f 177 SUPERFAMILY SSF54593 49 172 1.88E-24 T 31-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AF_1476 6c36949a06930d44501d4d8470a4100f 177 Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 50 170 1.5E-18 T 31-10-2018 IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain AF_0833 c3f09f47fba790cae239443eac5a62f3 125 Gene3D G3DSA:2.60.40.730 40 125 5.9E-32 T 31-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 AF_0833 c3f09f47fba790cae239443eac5a62f3 125 SUPERFAMILY SSF49367 40 124 2.49E-33 T 31-10-2018 IPR036073 Desulfoferrodoxin, ferrous iron-binding domain superfamily GO:0005506|GO:0016491|GO:0055114 AF_0833 c3f09f47fba790cae239443eac5a62f3 125 Gene3D G3DSA:2.20.28.100 1 38 1.9E-17 T 31-10-2018 IPR038094 Desulforodoxin domain superfamily AF_0833 c3f09f47fba790cae239443eac5a62f3 125 SUPERFAMILY SSF57802 3 37 1.96E-12 T 31-10-2018 AF_0833 c3f09f47fba790cae239443eac5a62f3 125 TIGRFAM TIGR00319 desulf_FeS4: desulfoferrodoxin FeS4 iron-binding domain 1 34 1.4E-21 T 31-10-2018 IPR004462 Desulforodoxin domain GO:0005506 AF_0833 c3f09f47fba790cae239443eac5a62f3 125 TIGRFAM TIGR00332 neela_ferrous: desulfoferrodoxin ferrous iron-binding domain 40 124 3.0E-35 T 31-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 AF_0833 c3f09f47fba790cae239443eac5a62f3 125 Pfam PF01880 Desulfoferrodoxin 42 124 7.7E-24 T 31-10-2018 IPR002742 Desulfoferrodoxin, ferrous iron-binding domain GO:0005506|GO:0016491|GO:0055114 AF_0833 c3f09f47fba790cae239443eac5a62f3 125 Pfam PF06397 Desulfoferrodoxin, N-terminal domain 2 37 5.2E-21 T 31-10-2018 IPR004462 Desulforodoxin domain GO:0005506 AF_0833 c3f09f47fba790cae239443eac5a62f3 125 TIGRFAM TIGR00320 dfx_rbo: desulfoferrodoxin 1 124 1.2E-72 T 31-10-2018 IPR004793 Desulfoferrodoxin GO:0005506|GO:0019430 AF_0730 e3b9e29d20acb0eaf1eaf26f2421b999 240 Pfam PF02361 Cobalt transport protein 9 211 1.9E-52 T 31-10-2018 IPR003339 ABC/ECF transporter, transmembrane component AF_0730 e3b9e29d20acb0eaf1eaf26f2421b999 240 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 16 207 5.7E-47 T 31-10-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 AF_1669 fea373c579be1ec5454b0730d7b627fc 150 SUPERFAMILY SSF54862 4 144 8.56E-28 T 31-10-2018 AF_1669 fea373c579be1ec5454b0730d7b627fc 150 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 47 58 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1669 fea373c579be1ec5454b0730d7b627fc 150 TIGRFAM TIGR02060 aprB: adenylylsulfate reductase, beta subunit 1 129 5.2E-78 T 31-10-2018 IPR011802 Adenylylsulphate reductase, beta subunit AF_1669 fea373c579be1ec5454b0730d7b627fc 150 Pfam PF13187 4Fe-4S dicluster domain 9 62 6.6E-10 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1669 fea373c579be1ec5454b0730d7b627fc 150 Gene3D G3DSA:3.30.720.40 68 150 1.4E-39 T 31-10-2018 IPR038465 APS reductase, beta subunit, C-terminal domain superfamily AF_1669 fea373c579be1ec5454b0730d7b627fc 150 Gene3D G3DSA:3.30.70.20 2 67 3.4E-29 T 31-10-2018 AF_1669 fea373c579be1ec5454b0730d7b627fc 150 Pfam PF12139 Adenosine-5'-phosphosulfate reductase beta subunit 64 144 2.5E-37 T 31-10-2018 IPR022738 Adenylylsulphate reductase, beta subunit, C-terminal AF_0209 5d73444a8ad94b1b2eed011f35529ef7 481 SUPERFAMILY SSF50475 3 313 3.37E-116 T 31-10-2018 AF_0209 5d73444a8ad94b1b2eed011f35529ef7 481 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 6 445 4.7E-190 T 31-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 AF_0209 5d73444a8ad94b1b2eed011f35529ef7 481 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 11 418 8.5E-171 T 31-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 AF_0209 5d73444a8ad94b1b2eed011f35529ef7 481 TIGRFAM TIGR03701 mena_SCO4490: menaquinone biosynthesis decarboxylase, SCO4490 family 8 437 2.6E-198 T 31-10-2018 IPR022390 4-hydroxybenzoate decarboxylase subunit C GO:0016831 AF_0209 5d73444a8ad94b1b2eed011f35529ef7 481 SUPERFAMILY SSF143968 314 476 1.03E-63 T 31-10-2018 AF_0209 5d73444a8ad94b1b2eed011f35529ef7 481 Gene3D G3DSA:3.40.1670.10 328 444 7.0E-44 T 31-10-2018 AF_0649 3712c9bba2f81a9c45e1b172e97a7acf 233 Hamap MF_01079 UPF0280 protein . 1 233 36.004 T 31-10-2018 IPR037456 MA1715-like AF_0649 3712c9bba2f81a9c45e1b172e97a7acf 233 PIRSF PIRSF006421 1 233 2.9E-84 T 31-10-2018 IPR007183 Uncharacterised protein family UPF0280 AF_0649 3712c9bba2f81a9c45e1b172e97a7acf 233 SUPERFAMILY SSF143631 2 219 4.84E-65 T 31-10-2018 IPR003374 ApbE-like superfamily AF_0649 3712c9bba2f81a9c45e1b172e97a7acf 233 Gene3D G3DSA:3.10.520.10 1 220 2.8E-65 T 31-10-2018 AF_0202 8f1d7e57434ea76c0e4182174f74ede4 380 SUPERFAMILY SSF53901 3 224 7.77E-35 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0202 8f1d7e57434ea76c0e4182174f74ede4 380 PIRSF PIRSF000429 1 371 2.3E-40 T 31-10-2018 IPR002155 Thiolase GO:0016747 AF_0202 8f1d7e57434ea76c0e4182174f74ede4 380 Gene3D G3DSA:3.40.47.10 1 378 6.8E-106 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0202 8f1d7e57434ea76c0e4182174f74ede4 380 SUPERFAMILY SSF53901 228 375 3.0E-20 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0202 8f1d7e57434ea76c0e4182174f74ede4 380 Pfam PF00108 Thiolase, N-terminal domain 3 219 6.9E-13 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AF_0092 f0c2c20b9325e27b5b0f481f6c8366ed 240 Pfam PF00005 ABC transporter 17 154 2.9E-32 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0092 f0c2c20b9325e27b5b0f481f6c8366ed 240 SMART SM00382 23 204 1.1E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0092 f0c2c20b9325e27b5b0f481f6c8366ed 240 ProSitePatterns PS00211 ABC transporters family signature. 127 141 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_0092 f0c2c20b9325e27b5b0f481f6c8366ed 240 SUPERFAMILY SSF52540 8 229 2.01E-73 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0092 f0c2c20b9325e27b5b0f481f6c8366ed 240 Gene3D G3DSA:3.40.50.300 1 240 3.0E-76 T 31-10-2018 AF_2394 e3ae476158520d3750cf8279d566bcce 563 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 1 149 6.2E-12 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AF_2394 e3ae476158520d3750cf8279d566bcce 563 SUPERFAMILY SSF52540 1 154 1.14E-41 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2394 e3ae476158520d3750cf8279d566bcce 563 TIGRFAM TIGR00437 feoB: ferrous iron transport protein B 163 532 1.8E-141 T 31-10-2018 IPR003373 Ferrous iron transport protein B GO:0005525|GO:0015093|GO:0015684|GO:0016021 AF_2394 e3ae476158520d3750cf8279d566bcce 563 Pfam PF07664 Ferrous iron transport protein B C terminus 369 420 3.4E-18 T 31-10-2018 IPR011640 Ferrous iron transport protein B, C-terminal GO:0015093|GO:0015684|GO:0016021 AF_2394 e3ae476158520d3750cf8279d566bcce 563 Pfam PF07670 Nucleoside recognition 265 358 1.0E-13 T 31-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 AF_2394 e3ae476158520d3750cf8279d566bcce 563 Pfam PF07670 Nucleoside recognition 426 536 1.6E-30 T 31-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 AF_2394 e3ae476158520d3750cf8279d566bcce 563 Pfam PF02421 Ferrous iron transport protein B 1 152 1.8E-63 T 31-10-2018 IPR030389 FeoB-type guanine nucleotide-binding (G) domain GO:0005525 AF_2394 e3ae476158520d3750cf8279d566bcce 563 Gene3D G3DSA:3.40.50.300 1 188 4.2E-50 T 31-10-2018 AF_1107 330c81d39aba28843339d84188109381 146 Gene3D G3DSA:3.10.690.10 11 139 1.9E-47 T 31-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 AF_1107 330c81d39aba28843339d84188109381 146 SUPERFAMILY SSF103256 17 131 9.02E-45 T 31-10-2018 IPR036104 Bifunctional nuclease superfamily GO:0004518 AF_1107 330c81d39aba28843339d84188109381 146 Pfam PF02577 Bifunctional nuclease 18 131 4.1E-45 T 31-10-2018 IPR003729 Bifunctional nuclease domain GO:0004518 AF_0952 9d19a171acf6da474670f14d148b8a32 378 SUPERFAMILY SSF56235 16 365 4.46E-91 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AF_0952 9d19a171acf6da474670f14d148b8a32 378 Pfam PF00310 Glutamine amidotransferases class-II 78 226 1.2E-13 T 31-10-2018 IPR017932 Glutamine amidotransferase type 2 domain AF_0952 9d19a171acf6da474670f14d148b8a32 378 PIRSF PIRSF018774 1 378 6.1E-204 T 31-10-2018 IPR012375 Glutamate synthase large subunit domain 1 stand-alone protein AF_0952 9d19a171acf6da474670f14d148b8a32 378 Gene3D G3DSA:3.60.20.10 51 377 3.2E-56 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AF_0545 6242b1fd771d8f350554c2f46e5d3132 308 SUPERFAMILY SSF103501 48 245 4.18E-20 T 31-10-2018 IPR036197 NarG-like superfamily AF_0545 6242b1fd771d8f350554c2f46e5d3132 308 Pfam PF02665 Nitrate reductase gamma subunit 90 244 6.0E-10 T 31-10-2018 IPR023234 NarG-like domain AF_0545 6242b1fd771d8f350554c2f46e5d3132 308 Gene3D G3DSA:1.20.950.20 84 246 1.1E-13 T 31-10-2018 AF_1646 94c9bc2361061960239aafb4a3fde9bb 261 Pfam PF00288 GHMP kinases N terminal domain 68 126 2.4E-6 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 AF_1646 94c9bc2361061960239aafb4a3fde9bb 261 Gene3D G3DSA:3.30.230.10 25 135 4.8E-5 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AF_1646 94c9bc2361061960239aafb4a3fde9bb 261 SUPERFAMILY SSF54211 2 130 4.17E-8 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AF_1646 94c9bc2361061960239aafb4a3fde9bb 261 PIRSF PIRSF016896 1 261 1.1E-90 T 31-10-2018 IPR012043 Pantoate kinase KEGG: 00770+2.7.1.169|MetaCyc: PWY-6654 AF_1643 3b4e1bd2a05a2831040cc46d5b0c2f88 426 SUPERFAMILY SSF143968 291 422 1.09E-35 T 31-10-2018 AF_1643 3b4e1bd2a05a2831040cc46d5b0c2f88 426 TIGRFAM TIGR00148 TIGR00148: decarboxylase, UbiD family 7 416 1.0E-145 T 31-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 AF_1643 3b4e1bd2a05a2831040cc46d5b0c2f88 426 Gene3D G3DSA:3.40.1670.10 306 415 3.8E-31 T 31-10-2018 AF_1643 3b4e1bd2a05a2831040cc46d5b0c2f88 426 SUPERFAMILY SSF50475 54 288 1.61E-52 T 31-10-2018 AF_1643 3b4e1bd2a05a2831040cc46d5b0c2f88 426 Pfam PF01977 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 54 393 6.4E-81 T 31-10-2018 IPR002830 UbiD decarboxylyase family GO:0016831 KEGG: 00130+4.1.1.98|MetaCyc: PWY-5855|MetaCyc: PWY-5856|MetaCyc: PWY-5857|MetaCyc: PWY-6708|MetaCyc: PWY-6978 AF_0969 65c80e29af57deda72a72af94b945d31 531 Pfam PF00474 Sodium:solute symporter family 36 450 1.7E-49 T 31-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AF_0969 65c80e29af57deda72a72af94b945d31 531 Gene3D G3DSA:1.20.1730.10 24 528 5.2E-59 T 31-10-2018 IPR038377 Sodium/glucose symporter superfamily AF_0916 b18e157e183d7b00468e5d3984380455 570 TIGRFAM TIGR00389 glyS_dimeric: glycine--tRNA ligase 1 553 3.2E-253 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AF_0916 b18e157e183d7b00468e5d3984380455 570 Gene3D G3DSA:3.40.50.800 460 569 1.1E-32 T 31-10-2018 IPR036621 Anticodon-binding domain superfamily AF_0916 b18e157e183d7b00468e5d3984380455 570 Gene3D G3DSA:1.20.1430.20 80 141 4.1E-149 T 31-10-2018 AF_0916 b18e157e183d7b00468e5d3984380455 570 SUPERFAMILY SSF55681 3 465 5.84E-108 T 31-10-2018 AF_0916 b18e157e183d7b00468e5d3984380455 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 187 204 7.2E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AF_0916 b18e157e183d7b00468e5d3984380455 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 204 214 7.2E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AF_0916 b18e157e183d7b00468e5d3984380455 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 418 430 7.2E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AF_0916 b18e157e183d7b00468e5d3984380455 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 155 172 7.2E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AF_0916 b18e157e183d7b00468e5d3984380455 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 136 148 7.2E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AF_0916 b18e157e183d7b00468e5d3984380455 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 22 36 7.2E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AF_0916 b18e157e183d7b00468e5d3984380455 570 PRINTS PR01043 Glycyl-tRNA synthetase signature 500 519 7.2E-56 T 31-10-2018 IPR002315 Glycyl-tRNA synthetase GO:0000166|GO:0004820|GO:0005524|GO:0005737|GO:0006426 KEGG: 00970+6.1.1.14|Reactome: R-HSA-379716|Reactome: R-HSA-379726 AF_0916 b18e157e183d7b00468e5d3984380455 570 Gene3D G3DSA:3.30.930.10 9 440 4.1E-149 T 31-10-2018 AF_0916 b18e157e183d7b00468e5d3984380455 570 Hamap MF_00253_A Glycine--tRNA ligase [glyQS]. 1 555 55.987 T 31-10-2018 IPR022960 Glycine-tRNA ligase, archaeal GO:0004820 KEGG: 00970+6.1.1.14 AF_0916 b18e157e183d7b00468e5d3984380455 570 SUPERFAMILY SSF52954 449 562 3.93E-35 T 31-10-2018 AF_0916 b18e157e183d7b00468e5d3984380455 570 Pfam PF00587 tRNA synthetase class II core domain (G, H, P, S and T) 155 225 4.7E-9 T 31-10-2018 IPR002314 Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_0916 b18e157e183d7b00468e5d3984380455 570 Gene3D G3DSA:1.10.30.30 351 409 4.1E-149 T 31-10-2018 AF_0916 b18e157e183d7b00468e5d3984380455 570 Pfam PF03129 Anticodon binding domain 463 552 1.7E-22 T 31-10-2018 IPR004154 Anticodon-binding AF_2199 be9bb572961b233fd19b54ad8f888158 416 ProSitePatterns PS00450 Aconitase family signature 1. 288 304 - T 31-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AF_2199 be9bb572961b233fd19b54ad8f888158 416 PRINTS PR00415 Aconitase family signature 185 198 4.5E-19 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AF_2199 be9bb572961b233fd19b54ad8f888158 416 PRINTS PR00415 Aconitase family signature 109 122 4.5E-19 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AF_2199 be9bb572961b233fd19b54ad8f888158 416 PRINTS PR00415 Aconitase family signature 348 361 4.5E-19 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AF_2199 be9bb572961b233fd19b54ad8f888158 416 PRINTS PR00415 Aconitase family signature 123 138 4.5E-19 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AF_2199 be9bb572961b233fd19b54ad8f888158 416 PRINTS PR00415 Aconitase family signature 199 212 4.5E-19 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AF_2199 be9bb572961b233fd19b54ad8f888158 416 PRINTS PR00415 Aconitase family signature 89 97 4.5E-19 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AF_2199 be9bb572961b233fd19b54ad8f888158 416 Gene3D G3DSA:3.30.499.20 4 266 1.2E-92 T 31-10-2018 AF_2199 be9bb572961b233fd19b54ad8f888158 416 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 4 413 1.3E-203 T 31-10-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 AF_2199 be9bb572961b233fd19b54ad8f888158 416 Gene3D G3DSA:3.30.499.10 269 415 6.2E-62 T 31-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 AF_2199 be9bb572961b233fd19b54ad8f888158 416 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 3 415 49.686 T 31-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AF_2199 be9bb572961b233fd19b54ad8f888158 416 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 3 414 3.4E-177 T 31-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AF_2199 be9bb572961b233fd19b54ad8f888158 416 Pfam PF00330 Aconitase family (aconitate hydratase) 7 407 4.6E-103 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AF_2199 be9bb572961b233fd19b54ad8f888158 416 ProSitePatterns PS01244 Aconitase family signature 2. 348 361 - T 31-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AF_2199 be9bb572961b233fd19b54ad8f888158 416 SUPERFAMILY SSF53732 1 415 3.4E-145 T 31-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 AF_1191 04e4790d2cfa15c5d6016fbab26f4623 277 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 114 134 - T 31-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 AF_1191 04e4790d2cfa15c5d6016fbab26f4623 277 Gene3D G3DSA:3.90.226.10 1 215 3.4E-64 T 31-10-2018 AF_1191 04e4790d2cfa15c5d6016fbab26f4623 277 Pfam PF00378 Enoyl-CoA hydratase/isomerase 13 269 6.6E-62 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AF_1191 04e4790d2cfa15c5d6016fbab26f4623 277 Gene3D G3DSA:1.10.12.10 216 264 8.9E-23 T 31-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AF_1191 04e4790d2cfa15c5d6016fbab26f4623 277 SUPERFAMILY SSF52096 5 269 2.36E-73 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AF_1191 04e4790d2cfa15c5d6016fbab26f4623 277 Hamap MF_01934 1,4-dihydroxy-2-naphthoyl-CoA synthase [menB]. 1 275 45.009 T 31-10-2018 IPR010198 1,4-Dihydroxy-2-naphthoyl-CoA synthase, MenB GO:0008935|GO:0009234 KEGG: 00130+4.1.3.36|MetaCyc: PWY-5837 AF_1319 08418b564e85bba60806e580893239c2 194 TIGRFAM TIGR04289 heavy_Cys: eight-cysteine-cluster domain 139 191 2.1E-22 T 31-10-2018 IPR027553 Eight-cysteine-cluster domain AF_1412 17d8df8a603fe789bcd14d1ea2e567ff 381 SMART SM00722 48 193 3.0E-6 T 31-10-2018 IPR006633 Carbohydrate-binding/sugar hydrolysis domain AF_1412 17d8df8a603fe789bcd14d1ea2e567ff 381 Gene3D G3DSA:2.160.20.10 27 302 6.4E-13 T 31-10-2018 IPR012334 Pectin lyase fold AF_1412 17d8df8a603fe789bcd14d1ea2e567ff 381 Pfam PF05048 Periplasmic copper-binding protein (NosD) 81 208 1.2E-8 T 31-10-2018 IPR007742 Periplasmic copper-binding protein NosD, beta helix domain Reactome: R-HSA-8951664|Reactome: R-HSA-983168 AF_1412 17d8df8a603fe789bcd14d1ea2e567ff 381 SUPERFAMILY SSF51126 19 280 1.24E-27 T 31-10-2018 IPR011050 Pectin lyase fold/virulence factor AF_0723 df5be8b30c48b8aa6c48156ee514f395 298 Pfam PF01888 CbiD 38 245 1.2E-40 T 31-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 AF_0723 df5be8b30c48b8aa6c48156ee514f395 298 Gene3D G3DSA:3.30.2110.10 40 192 3.2E-53 T 31-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 AF_0723 df5be8b30c48b8aa6c48156ee514f395 298 SUPERFAMILY SSF111342 1 274 1.44E-75 T 31-10-2018 IPR036074 CbiD superfamily GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 AF_0723 df5be8b30c48b8aa6c48156ee514f395 298 Gene3D G3DSA:3.40.50.10720 193 282 2.1E-56 T 31-10-2018 AF_0723 df5be8b30c48b8aa6c48156ee514f395 298 Gene3D G3DSA:3.30.1990.10 1 39 1.3E-29 T 31-10-2018 AF_0723 df5be8b30c48b8aa6c48156ee514f395 298 Hamap MF_00787 Cobalt-precorrin-5B C(1)-methyltransferase [cbiD]. 38 292 16.388 T 31-10-2018 IPR002748 Cobalt-precorrin-5B C(1)-methyltransferase CbiD GO:0008168|GO:0009236 KEGG: 00860+2.1.1.195|MetaCyc: PWY-7377 AF_1652 e1f86edd9a67c41c71a1c274efc34049 910 ProSitePatterns PS00138 Serine proteases, subtilase family, serine active site. 304 314 - T 31-10-2018 IPR023828 Peptidase S8, subtilisin, Ser-active site AF_1652 e1f86edd9a67c41c71a1c274efc34049 910 Gene3D G3DSA:2.60.40.1120 462 530 6.2E-5 T 31-10-2018 AF_1652 e1f86edd9a67c41c71a1c274efc34049 910 Pfam PF00801 PKD domain 385 448 8.7E-14 T 31-10-2018 IPR000601 PKD domain AF_1652 e1f86edd9a67c41c71a1c274efc34049 910 Pfam PF00082 Subtilase family 213 349 6.4E-37 T 31-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AF_1652 e1f86edd9a67c41c71a1c274efc34049 910 Gene3D G3DSA:3.40.50.200 156 371 4.8E-53 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AF_1652 e1f86edd9a67c41c71a1c274efc34049 910 SUPERFAMILY SSF49299 368 459 1.26E-16 T 31-10-2018 IPR035986 PKD domain superfamily AF_1652 e1f86edd9a67c41c71a1c274efc34049 910 SUPERFAMILY SSF49299 830 909 6.02E-10 T 31-10-2018 IPR035986 PKD domain superfamily AF_1652 e1f86edd9a67c41c71a1c274efc34049 910 SUPERFAMILY SSF49464 462 529 1.11E-6 T 31-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily AF_1652 e1f86edd9a67c41c71a1c274efc34049 910 Gene3D G3DSA:2.60.40.10 372 458 2.8E-18 T 31-10-2018 IPR013783 Immunoglobulin-like fold AF_1652 e1f86edd9a67c41c71a1c274efc34049 910 Gene3D G3DSA:2.60.40.10 822 910 9.4E-7 T 31-10-2018 IPR013783 Immunoglobulin-like fold AF_1652 e1f86edd9a67c41c71a1c274efc34049 910 SUPERFAMILY SSF52743 206 395 2.09E-52 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AF_1652 e1f86edd9a67c41c71a1c274efc34049 910 SMART SM00089 831 905 8.1E-11 T 31-10-2018 IPR022409 PKD/Chitinase domain AF_1652 e1f86edd9a67c41c71a1c274efc34049 910 SMART SM00089 377 459 7.6E-26 T 31-10-2018 IPR022409 PKD/Chitinase domain AF_0509 6a8b3c2815e5be81316bf5ae0c5e7d54 198 SUPERFAMILY SSF52317 2 194 1.32E-48 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_0509 6a8b3c2815e5be81316bf5ae0c5e7d54 198 TIGRFAM TIGR03800 PLP_synth_Pdx2: pyridoxal 5'-phosphate synthase, glutaminase subunit Pdx2 2 193 1.9E-62 T 31-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AF_0509 6a8b3c2815e5be81316bf5ae0c5e7d54 198 PIRSF PIRSF005639 1 198 5.2E-70 T 31-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AF_0509 6a8b3c2815e5be81316bf5ae0c5e7d54 198 Gene3D G3DSA:3.40.50.880 1 198 2.8E-62 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_0509 6a8b3c2815e5be81316bf5ae0c5e7d54 198 Hamap MF_01615 Pyridoxal 5'-phosphate synthase subunit PdxT [pdxT]. 3 194 35.459 T 31-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AF_0509 6a8b3c2815e5be81316bf5ae0c5e7d54 198 Pfam PF01174 SNO glutamine amidotransferase family 5 193 1.1E-50 T 31-10-2018 IPR002161 Pyridoxal 5'-phosphate synthase subunit PdxT/SNO GO:0004359|GO:0042819|GO:0042823 KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AF_0509 6a8b3c2815e5be81316bf5ae0c5e7d54 198 ProSitePatterns PS01236 PdxT/SNO family family signature. 46 56 - T 31-10-2018 IPR021196 PdxT/SNO family, conserved site KEGG: 00220+3.5.1.2|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|KEGG: 00750+4.3.3.6|MetaCyc: PWY-6466 AF_1820 7bf501d5ee118a00dd92a70a00954f77 791 Pfam PF02687 FtsX-like permease family 303 394 1.2E-8 T 31-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AF_1820 7bf501d5ee118a00dd92a70a00954f77 791 Pfam PF02687 FtsX-like permease family 690 781 2.0E-11 T 31-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AF_0733 ba3de9a5d951a4be8d9708486da59c52 296 PIRSF PIRSF005303 2 296 4.3E-77 T 31-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 AF_0733 ba3de9a5d951a4be8d9708486da59c52 296 SUPERFAMILY SSF56042 141 282 1.22E-18 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AF_0733 ba3de9a5d951a4be8d9708486da59c52 296 SUPERFAMILY SSF55326 7 138 2.09E-29 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AF_0733 ba3de9a5d951a4be8d9708486da59c52 296 Gene3D G3DSA:3.30.1330.10 3 142 1.0E-31 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AF_0733 ba3de9a5d951a4be8d9708486da59c52 296 TIGRFAM TIGR01379 thiL: thiamine-phosphate kinase 7 296 1.6E-85 T 31-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 AF_0733 ba3de9a5d951a4be8d9708486da59c52 296 Pfam PF00586 AIR synthase related protein, N-terminal domain 32 137 3.4E-20 T 31-10-2018 IPR016188 PurM-like, N-terminal domain AF_0733 ba3de9a5d951a4be8d9708486da59c52 296 Gene3D G3DSA:3.90.650.10 143 296 3.1E-29 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AF_0733 ba3de9a5d951a4be8d9708486da59c52 296 Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. 6 296 24.799 T 31-10-2018 IPR006283 Thiamine-monophosphate kinase GO:0009030|GO:0009228 KEGG: 00730+2.7.4.16|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6896|MetaCyc: PWY-6897 AF_1294 9fe71dc156926ebee555ad272762f3c2 178 TIGRFAM TIGR00267 TIGR00267: TIGR00267 family protein 3 174 5.5E-80 T 31-10-2018 IPR006682 Conserved hypothetical protein CHP00267 AF_1294 9fe71dc156926ebee555ad272762f3c2 178 Pfam PF01988 VIT family 81 169 7.1E-11 T 31-10-2018 IPR008217 Ccc1 family AF_1195 f5b32417145ea51e2da18062744711d9 479 Gene3D G3DSA:3.40.50.300 1 165 6.0E-39 T 31-10-2018 AF_1195 f5b32417145ea51e2da18062744711d9 479 SMART SM00382 35 167 1.8E-8 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1195 f5b32417145ea51e2da18062744711d9 479 Gene3D G3DSA:1.10.8.60 167 230 1.0E-12 T 31-10-2018 AF_1195 f5b32417145ea51e2da18062744711d9 479 Hamap MF_01508 Replication factor C large subunit [rfcL]. 1 463 35.919 T 31-10-2018 IPR023935 Replication factor C, large subunit AF_1195 f5b32417145ea51e2da18062744711d9 479 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 39 162 1.7E-14 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AF_1195 f5b32417145ea51e2da18062744711d9 479 SUPERFAMILY SSF52540 2 226 1.3E-43 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1981 1f372dc9dab6a1e01c262ef4b6eff542 264 Pfam PF00950 ABC 3 transport family 4 262 5.1E-73 T 31-10-2018 IPR001626 ABC transporter, TroCD-like GO:0005887|GO:0042626|GO:0043190|GO:0055085 AF_1981 1f372dc9dab6a1e01c262ef4b6eff542 264 SUPERFAMILY SSF81345 5 263 4.18E-26 T 31-10-2018 IPR037294 ABC transporter, BtuC-like AF_1037 8028c397d81dfeb49c6df344b09f6ab7 270 Pfam PF01739 CheR methyltransferase, SAM binding domain 69 262 2.9E-67 T 31-10-2018 IPR022642 MCP methyltransferase, CheR-type, SAM-binding domain, C-terminal AF_1037 8028c397d81dfeb49c6df344b09f6ab7 270 PRINTS PR00996 Glutamate methyltransferase family signature 137 153 3.5E-40 T 31-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AF_1037 8028c397d81dfeb49c6df344b09f6ab7 270 PRINTS PR00996 Glutamate methyltransferase family signature 62 74 3.5E-40 T 31-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AF_1037 8028c397d81dfeb49c6df344b09f6ab7 270 PRINTS PR00996 Glutamate methyltransferase family signature 204 218 3.5E-40 T 31-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AF_1037 8028c397d81dfeb49c6df344b09f6ab7 270 PRINTS PR00996 Glutamate methyltransferase family signature 223 246 3.5E-40 T 31-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AF_1037 8028c397d81dfeb49c6df344b09f6ab7 270 PRINTS PR00996 Glutamate methyltransferase family signature 24 37 3.5E-40 T 31-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AF_1037 8028c397d81dfeb49c6df344b09f6ab7 270 PRINTS PR00996 Glutamate methyltransferase family signature 104 124 3.5E-40 T 31-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AF_1037 8028c397d81dfeb49c6df344b09f6ab7 270 SMART SM00138 2 265 4.1E-141 T 31-10-2018 IPR000780 MCP methyltransferase, CheR-type GO:0008757 AF_1037 8028c397d81dfeb49c6df344b09f6ab7 270 Gene3D G3DSA:1.10.155.10 1 67 1.2E-12 T 31-10-2018 IPR036804 Chemotaxis receptor methyltransferase CheR, N-terminal domain superfamily AF_1037 8028c397d81dfeb49c6df344b09f6ab7 270 SUPERFAMILY SSF47757 3 68 1.18E-15 T 31-10-2018 AF_1037 8028c397d81dfeb49c6df344b09f6ab7 270 PIRSF PIRSF000410 2 268 1.3E-80 T 31-10-2018 IPR026024 Chemotaxis protein methyltransferase CheR AF_1037 8028c397d81dfeb49c6df344b09f6ab7 270 Pfam PF03705 CheR methyltransferase, all-alpha domain 5 54 1.6E-14 T 31-10-2018 IPR022641 Chemotaxis receptor methyltransferase CheR, N-terminal AF_1037 8028c397d81dfeb49c6df344b09f6ab7 270 Gene3D G3DSA:3.40.50.150 68 267 9.9E-64 T 31-10-2018 AF_1037 8028c397d81dfeb49c6df344b09f6ab7 270 SUPERFAMILY SSF53335 69 248 3.95E-47 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_0848 c538ec1f030f44947cb54c2f7e410883 284 SUPERFAMILY SSF54631 81 198 5.59E-35 T 31-10-2018 AF_0848 c538ec1f030f44947cb54c2f7e410883 284 SUPERFAMILY SSF54631 1 56 9.9E-12 T 31-10-2018 AF_0848 c538ec1f030f44947cb54c2f7e410883 284 Pfam PF00571 CBS domain 2 53 3.4E-9 T 31-10-2018 IPR000644 CBS domain AF_0848 c538ec1f030f44947cb54c2f7e410883 284 Pfam PF00571 CBS domain 233 280 1.8E-10 T 31-10-2018 IPR000644 CBS domain AF_0848 c538ec1f030f44947cb54c2f7e410883 284 Pfam PF00571 CBS domain 81 135 1.6E-15 T 31-10-2018 IPR000644 CBS domain AF_0848 c538ec1f030f44947cb54c2f7e410883 284 Pfam PF00571 CBS domain 145 197 2.6E-14 T 31-10-2018 IPR000644 CBS domain AF_0848 c538ec1f030f44947cb54c2f7e410883 284 SUPERFAMILY SSF54631 206 282 5.07E-10 T 31-10-2018 AF_0848 c538ec1f030f44947cb54c2f7e410883 284 Gene3D G3DSA:3.10.580.10 1 137 2.0E-38 T 31-10-2018 AF_0848 c538ec1f030f44947cb54c2f7e410883 284 Gene3D G3DSA:3.10.580.10 143 284 5.1E-28 T 31-10-2018 AF_0848 c538ec1f030f44947cb54c2f7e410883 284 SMART SM00116 234 281 7.6E-6 T 31-10-2018 IPR000644 CBS domain AF_0848 c538ec1f030f44947cb54c2f7e410883 284 SMART SM00116 8 57 2.7E-6 T 31-10-2018 IPR000644 CBS domain AF_0848 c538ec1f030f44947cb54c2f7e410883 284 SMART SM00116 88 136 3.0E-13 T 31-10-2018 IPR000644 CBS domain AF_0848 c538ec1f030f44947cb54c2f7e410883 284 SMART SM00116 152 199 3.8E-9 T 31-10-2018 IPR000644 CBS domain AF_2283 29ed31369873867272fce51306795381 133 Gene3D G3DSA:3.30.420.80 1 133 6.2E-62 T 31-10-2018 IPR036967 Ribosomal protein S11 superfamily GO:0003735|GO:0005840|GO:0006412 AF_2283 29ed31369873867272fce51306795381 133 Hamap MF_01310 30S ribosomal protein S11 [rpsK]. 4 130 23.605 T 31-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AF_2283 29ed31369873867272fce51306795381 133 TIGRFAM TIGR03628 arch_S11P: ribosomal protein uS11 9 125 9.2E-66 T 31-10-2018 IPR019961 Ribosomal protein S11, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_2283 29ed31369873867272fce51306795381 133 Pfam PF00411 Ribosomal protein S11 11 129 6.5E-46 T 31-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AF_2283 29ed31369873867272fce51306795381 133 SUPERFAMILY SSF53137 9 131 1.31E-38 T 31-10-2018 AF_2283 29ed31369873867272fce51306795381 133 ProSitePatterns PS00054 Ribosomal protein S11 signature. 98 120 - T 31-10-2018 IPR018102 Ribosomal S11, conserved site AF_2283 29ed31369873867272fce51306795381 133 PIRSF PIRSF002131 1 133 6.0E-35 T 31-10-2018 IPR001971 Ribosomal protein S11 GO:0003735|GO:0005840|GO:0006412 AF_1886 5b05faeeb16b9210bf436f21f48b55cc 512 Gene3D G3DSA:3.90.1110.10 186 341 6.9E-53 T 31-10-2018 IPR037034 RNA polymerase Rpb2, domain 2 superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1886 5b05faeeb16b9210bf436f21f48b55cc 512 Pfam PF04563 RNA polymerase beta subunit 17 403 8.5E-39 T 31-10-2018 IPR007644 RNA polymerase, beta subunit, protrusion GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1886 5b05faeeb16b9210bf436f21f48b55cc 512 Pfam PF04565 RNA polymerase Rpb2, domain 3 424 488 5.5E-27 T 31-10-2018 IPR007645 RNA polymerase Rpb2, domain 3 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1886 5b05faeeb16b9210bf436f21f48b55cc 512 SUPERFAMILY SSF64484 5 510 5.19E-133 T 31-10-2018 AF_1886 5b05faeeb16b9210bf436f21f48b55cc 512 Pfam PF04561 RNA polymerase Rpb2, domain 2 183 356 1.5E-29 T 31-10-2018 IPR007642 RNA polymerase Rpb2, domain 2 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1886 5b05faeeb16b9210bf436f21f48b55cc 512 Gene3D G3DSA:3.90.1100.10 342 506 1.1E-52 T 31-10-2018 AF_1539 6ef491637b195e251b41f8509b023ad4 291 Gene3D G3DSA:3.40.50.261 127 291 3.4E-68 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1539 6ef491637b195e251b41f8509b023ad4 291 SUPERFAMILY SSF52210 126 289 2.49E-49 T 31-10-2018 IPR016102 Succinyl-CoA synthetase-like KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1539 6ef491637b195e251b41f8509b023ad4 291 PRINTS PR01798 Succinyl-CoA synthase signature 180 198 1.1E-37 T 31-10-2018 AF_1539 6ef491637b195e251b41f8509b023ad4 291 PRINTS PR01798 Succinyl-CoA synthase signature 211 224 1.1E-37 T 31-10-2018 AF_1539 6ef491637b195e251b41f8509b023ad4 291 PRINTS PR01798 Succinyl-CoA synthase signature 85 102 1.1E-37 T 31-10-2018 AF_1539 6ef491637b195e251b41f8509b023ad4 291 PRINTS PR01798 Succinyl-CoA synthase signature 242 259 1.1E-37 T 31-10-2018 AF_1539 6ef491637b195e251b41f8509b023ad4 291 ProSitePatterns PS01216 ATP-citrate lyase / succinyl-CoA ligases family signature 1. 155 184 - T 31-10-2018 IPR033847 ATP-citrate lyase/succinyl-CoA ligase, conserved site AF_1539 6ef491637b195e251b41f8509b023ad4 291 TIGRFAM TIGR01019 sucCoAalpha: succinate-CoA ligase, alpha subunit 6 290 1.8E-133 T 31-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AF_1539 6ef491637b195e251b41f8509b023ad4 291 Pfam PF00549 CoA-ligase 154 273 3.2E-18 T 31-10-2018 IPR005811 ATP-citrate lyase/succinyl-CoA ligase GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384 AF_1539 6ef491637b195e251b41f8509b023ad4 291 Pfam PF02629 CoA binding domain 9 102 5.4E-31 T 31-10-2018 IPR003781 CoA-binding GO:0048037 AF_1539 6ef491637b195e251b41f8509b023ad4 291 ProSitePatterns PS00399 ATP-citrate lyase / succinyl-CoA ligases family active site. 238 251 - T 31-10-2018 IPR017440 ATP-citrate lyase/succinyl-CoA ligase, active site AF_1539 6ef491637b195e251b41f8509b023ad4 291 Gene3D G3DSA:3.40.50.720 1 126 5.4E-49 T 31-10-2018 AF_1539 6ef491637b195e251b41f8509b023ad4 291 SMART SM00881 7 103 7.8E-33 T 31-10-2018 IPR003781 CoA-binding GO:0048037 AF_1539 6ef491637b195e251b41f8509b023ad4 291 Hamap MF_01988 Succinate--CoA ligase [ADP-forming] subunit alpha [sucD]. 4 290 42.143 T 31-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AF_1539 6ef491637b195e251b41f8509b023ad4 291 PIRSF PIRSF001553 1 291 4.1E-133 T 31-10-2018 IPR005810 Succinyl-CoA ligase, alpha subunit GO:0003824 KEGG: 00020+6.2.1.5|KEGG: 00640+6.2.1.5|KEGG: 00660+6.2.1.5|KEGG: 00720+6.2.1.5|MetaCyc: PWY-5392|MetaCyc: PWY-5537|MetaCyc: PWY-5538|MetaCyc: PWY-5690|MetaCyc: PWY-5913|MetaCyc: PWY-6728|MetaCyc: PWY-6969|MetaCyc: PWY-7384|Reactome: R-HSA-71403 AF_1539 6ef491637b195e251b41f8509b023ad4 291 SUPERFAMILY SSF51735 3 125 4.84E-42 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0168 5bbdac6a082a9bca45db7af3240c04af 92 SUPERFAMILY SSF46785 9 80 1.42E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0168 5bbdac6a082a9bca45db7af3240c04af 92 Gene3D G3DSA:1.10.10.10 1 92 1.5E-35 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0168 5bbdac6a082a9bca45db7af3240c04af 92 Pfam PF12840 Helix-turn-helix domain 22 78 1.8E-18 T 31-10-2018 AF_2032 3f40d524d0995b02ab2d150312491925 672 Gene3D G3DSA:3.30.450.20 380 500 3.9E-22 T 31-10-2018 AF_2032 3f40d524d0995b02ab2d150312491925 672 SUPERFAMILY SSF55785 369 486 5.23E-19 T 31-10-2018 IPR035965 PAS domain superfamily AF_2032 3f40d524d0995b02ab2d150312491925 672 Pfam PF00512 His Kinase A (phospho-acceptor) domain 595 648 8.6E-7 T 31-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AF_2032 3f40d524d0995b02ab2d150312491925 672 Gene3D G3DSA:3.30.450.20 133 256 1.7E-30 T 31-10-2018 AF_2032 3f40d524d0995b02ab2d150312491925 672 Pfam PF08448 PAS fold 23 127 1.3E-11 T 31-10-2018 IPR013656 PAS fold-4 AF_2032 3f40d524d0995b02ab2d150312491925 672 Pfam PF08448 PAS fold 390 489 1.3E-15 T 31-10-2018 IPR013656 PAS fold-4 AF_2032 3f40d524d0995b02ab2d150312491925 672 SMART SM00091 585 651 200.0 T 31-10-2018 IPR000014 PAS domain AF_2032 3f40d524d0995b02ab2d150312491925 672 SMART SM00091 384 447 1.3E-4 T 31-10-2018 IPR000014 PAS domain AF_2032 3f40d524d0995b02ab2d150312491925 672 SMART SM00091 16 79 1.2E-6 T 31-10-2018 IPR000014 PAS domain AF_2032 3f40d524d0995b02ab2d150312491925 672 SMART SM00091 130 198 3.4E-9 T 31-10-2018 IPR000014 PAS domain AF_2032 3f40d524d0995b02ab2d150312491925 672 SMART SM00091 258 324 6.0E-11 T 31-10-2018 IPR000014 PAS domain AF_2032 3f40d524d0995b02ab2d150312491925 672 SUPERFAMILY SSF55785 243 370 1.55E-29 T 31-10-2018 IPR035965 PAS domain superfamily AF_2032 3f40d524d0995b02ab2d150312491925 672 SMART SM00086 85 125 4.9 T 31-10-2018 IPR001610 PAC motif AF_2032 3f40d524d0995b02ab2d150312491925 672 SMART SM00086 205 246 14.0 T 31-10-2018 IPR001610 PAC motif AF_2032 3f40d524d0995b02ab2d150312491925 672 SMART SM00086 331 372 0.01 T 31-10-2018 IPR001610 PAC motif AF_2032 3f40d524d0995b02ab2d150312491925 672 SMART SM00388 592 650 2.0E-7 T 31-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AF_2032 3f40d524d0995b02ab2d150312491925 672 SUPERFAMILY SSF55785 20 125 4.04E-18 T 31-10-2018 IPR035965 PAS domain superfamily AF_2032 3f40d524d0995b02ab2d150312491925 672 Gene3D G3DSA:3.30.450.20 257 379 2.9E-25 T 31-10-2018 AF_2032 3f40d524d0995b02ab2d150312491925 672 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 15 131 6.9E-18 T 31-10-2018 IPR000014 PAS domain AF_2032 3f40d524d0995b02ab2d150312491925 672 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 127 253 3.7E-33 T 31-10-2018 IPR000014 PAS domain AF_2032 3f40d524d0995b02ab2d150312491925 672 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 380 492 1.5E-11 T 31-10-2018 IPR000014 PAS domain AF_2032 3f40d524d0995b02ab2d150312491925 672 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 254 379 1.1E-35 T 31-10-2018 IPR000014 PAS domain AF_2032 3f40d524d0995b02ab2d150312491925 672 Gene3D G3DSA:3.30.450.20 20 132 3.6E-18 T 31-10-2018 AF_2032 3f40d524d0995b02ab2d150312491925 672 Pfam PF00989 PAS fold 258 369 5.8E-17 T 31-10-2018 IPR013767 PAS fold GO:0006355 AF_2032 3f40d524d0995b02ab2d150312491925 672 Pfam PF00989 PAS fold 130 243 6.4E-14 T 31-10-2018 IPR013767 PAS fold GO:0006355 AF_2032 3f40d524d0995b02ab2d150312491925 672 SUPERFAMILY SSF55785 125 244 3.14E-25 T 31-10-2018 IPR035965 PAS domain superfamily AF_2384 7884d38deea05b7bd5bda5fbf8432fcd 822 Gene3D G3DSA:3.40.228.10 344 657 1.5E-58 T 31-10-2018 AF_2384 7884d38deea05b7bd5bda5fbf8432fcd 822 Gene3D G3DSA:3.30.2070.10 529 633 1.5E-58 T 31-10-2018 AF_2384 7884d38deea05b7bd5bda5fbf8432fcd 822 SMART SM00926 39 93 1.3E-19 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_2384 7884d38deea05b7bd5bda5fbf8432fcd 822 Gene3D G3DSA:2.20.25.90 32 97 3.2E-25 T 31-10-2018 AF_2384 7884d38deea05b7bd5bda5fbf8432fcd 822 Gene3D G3DSA:2.40.40.20 678 822 1.4E-31 T 31-10-2018 AF_2384 7884d38deea05b7bd5bda5fbf8432fcd 822 Pfam PF00384 Molybdopterin oxidoreductase 96 572 9.3E-50 T 31-10-2018 IPR006656 Molybdopterin oxidoreductase GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_2384 7884d38deea05b7bd5bda5fbf8432fcd 822 Gene3D G3DSA:3.40.50.740 441 577 1.5E-58 T 31-10-2018 AF_2384 7884d38deea05b7bd5bda5fbf8432fcd 822 Pfam PF01568 Molydopterin dinucleotide binding domain 693 814 3.0E-12 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AF_2384 7884d38deea05b7bd5bda5fbf8432fcd 822 TIGRFAM TIGR01409 TAT_signal_seq: Tat (twin-arginine translocation) pathway signal sequence 2 22 3.2E-4 T 31-10-2018 IPR019546 Twin-arginine translocation pathway, signal sequence, bacterial/archaeal AF_2384 7884d38deea05b7bd5bda5fbf8432fcd 822 Gene3D G3DSA:3.40.228.10 183 284 1.2E-48 T 31-10-2018 AF_2384 7884d38deea05b7bd5bda5fbf8432fcd 822 SUPERFAMILY SSF53706 35 566 7.98E-150 T 31-10-2018 AF_2384 7884d38deea05b7bd5bda5fbf8432fcd 822 Gene3D G3DSA:3.40.50.740 98 182 1.2E-48 T 31-10-2018 AF_2384 7884d38deea05b7bd5bda5fbf8432fcd 822 SUPERFAMILY SSF50692 645 822 4.29E-19 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AF_2384 7884d38deea05b7bd5bda5fbf8432fcd 822 Pfam PF04879 Molybdopterin oxidoreductase Fe4S4 domain 40 93 3.2E-17 T 31-10-2018 IPR006963 Molybdopterin oxidoreductase, 4Fe-4S domain GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_0635 6ab0d5fb8b521bcdf2dd27ba3ddc4984 330 SUPERFAMILY SSF53850 39 329 9.89E-85 T 31-10-2018 AF_0635 6ab0d5fb8b521bcdf2dd27ba3ddc4984 330 Pfam PF16868 NMT1-like family 43 327 6.5E-99 T 31-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family AF_0635 6ab0d5fb8b521bcdf2dd27ba3ddc4984 330 Gene3D G3DSA:3.40.190.10 43 327 1.8E-111 T 31-10-2018 AF_0635 6ab0d5fb8b521bcdf2dd27ba3ddc4984 330 TIGRFAM TIGR02122 TRAP_TAXI: TRAP transporter solute receptor, TAXI family 1 327 1.2E-127 T 31-10-2018 IPR011852 TRAP transporter solute receptor, TAXI family AF_0635 6ab0d5fb8b521bcdf2dd27ba3ddc4984 330 Gene3D G3DSA:3.40.190.10 127 264 1.8E-111 T 31-10-2018 AF_2382 aecd6e71af3e1c859ded467459073eeb 254 Gene3D G3DSA:3.40.50.300 1 254 6.4E-92 T 31-10-2018 AF_2382 aecd6e71af3e1c859ded467459073eeb 254 Hamap MF_02040 Iron-sulfur cluster carrier protein. 12 249 34.271 T 31-10-2018 IPR019591 Mrp/NBP35 ATP-binding protein AF_2382 aecd6e71af3e1c859ded467459073eeb 254 SUPERFAMILY SSF52540 8 240 7.53E-55 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2382 aecd6e71af3e1c859ded467459073eeb 254 Pfam PF10609 NUBPL iron-transfer P-loop NTPase 16 241 5.2E-91 T 31-10-2018 IPR033756 Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 AF_2367 a531105b70765e384ecda249365979eb 188 Pfam PF00583 Acetyltransferase (GNAT) family 12 161 5.6E-29 T 31-10-2018 IPR000182 GNAT domain AF_2367 a531105b70765e384ecda249365979eb 188 SUPERFAMILY SSF55729 3 186 3.49E-19 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase AF_2367 a531105b70765e384ecda249365979eb 188 Gene3D G3DSA:3.40.630.30 2 186 3.9E-19 T 31-10-2018 AF_2367 a531105b70765e384ecda249365979eb 188 PIRSF PIRSF037663 85 175 3.3E-9 T 31-10-2018 IPR017255 Acetyltransferase, GNAT, predicted AF_2367 a531105b70765e384ecda249365979eb 188 PIRSF PIRSF037663 1 75 0.16 T 31-10-2018 IPR017255 Acetyltransferase, GNAT, predicted AF_0575 bff7f4c9efde7c0329e972a6e0d316fa 209 Pfam PF00753 Metallo-beta-lactamase superfamily 9 186 8.6E-36 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_0575 bff7f4c9efde7c0329e972a6e0d316fa 209 SMART SM00849 12 186 7.8E-41 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_0575 bff7f4c9efde7c0329e972a6e0d316fa 209 SUPERFAMILY SSF56281 12 201 2.75E-51 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_0575 bff7f4c9efde7c0329e972a6e0d316fa 209 Gene3D G3DSA:3.60.15.10 4 206 2.5E-52 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_0011 17306b6ab013112d6d939b5338d7ca4e 239 Gene3D G3DSA:3.40.50.280 108 238 1.7E-43 T 31-10-2018 AF_0011 17306b6ab013112d6d939b5338d7ca4e 239 SMART SM01018 31 113 3.4E-24 T 31-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AF_0011 17306b6ab013112d6d939b5338d7ca4e 239 SUPERFAMILY SSF47644 30 112 7.32E-17 T 31-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AF_0011 17306b6ab013112d6d939b5338d7ca4e 239 Gene3D G3DSA:1.10.1240.10 32 107 8.1E-24 T 31-10-2018 IPR036594 Methionine synthase domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AF_0011 17306b6ab013112d6d939b5338d7ca4e 239 SUPERFAMILY SSF52242 99 237 2.62E-40 T 31-10-2018 IPR036724 Cobalamin-binding domain superfamily GO:0031419|GO:0046872 Reactome: R-HSA-196741 AF_0011 17306b6ab013112d6d939b5338d7ca4e 239 Pfam PF02607 B12 binding domain 35 105 6.4E-13 T 31-10-2018 IPR003759 Cobalamin (vitamin B12)-binding module, cap domain Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AF_0011 17306b6ab013112d6d939b5338d7ca4e 239 Pfam PF02310 B12 binding domain 119 225 6.8E-26 T 31-10-2018 IPR006158 Cobalamin (vitamin B12)-binding domain GO:0031419|GO:0046872 Reactome: R-HSA-196741 AF_1526 2ad34dae2011ec79aa4f092a810a89af 145 SUPERFAMILY SSF52402 1 144 4.35E-11 T 31-10-2018 AF_1526 2ad34dae2011ec79aa4f092a810a89af 145 Pfam PF00582 Universal stress protein family 2 144 2.1E-19 T 31-10-2018 IPR006016 UspA AF_1526 2ad34dae2011ec79aa4f092a810a89af 145 Gene3D G3DSA:3.40.50.620 1 144 2.3E-10 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_0094 3cb9ba48ce99a5ef289c87e88b090fe2 342 Pfam PF13531 Bacterial extracellular solute-binding protein 35 319 6.0E-38 T 31-10-2018 AF_0094 3cb9ba48ce99a5ef289c87e88b090fe2 342 SUPERFAMILY SSF53850 33 329 8.23E-70 T 31-10-2018 AF_0094 3cb9ba48ce99a5ef289c87e88b090fe2 342 Gene3D G3DSA:3.40.190.10 35 328 3.7E-143 T 31-10-2018 AF_0094 3cb9ba48ce99a5ef289c87e88b090fe2 342 TIGRFAM TIGR03730 tungstate_WtpA: tungstate ABC transporter binding protein WtpA 34 306 2.1E-131 T 31-10-2018 IPR022498 Tungstate ABC transporter, substrate-binding protein WtpA GO:1901359 AF_0094 3cb9ba48ce99a5ef289c87e88b090fe2 342 Gene3D G3DSA:3.40.190.10 113 283 3.7E-143 T 31-10-2018 AF_0947 dad23c5e672c39a238194329ba08c08c 132 Pfam PF01934 Protein of unknown function DUF86 5 120 2.1E-21 T 31-10-2018 IPR008201 Protein of unknown function DUF86 AF_0947 dad23c5e672c39a238194329ba08c08c 132 Gene3D G3DSA:1.20.120.580 1 128 4.0E-10 T 31-10-2018 IPR037038 Bsu32300-like superfamily AF_0744 ef69d70c40b2f695f8fadab5e3ad6f9d 565 Gene3D G3DSA:2.40.30.10 383 477 1.1E-25 T 31-10-2018 AF_0744 ef69d70c40b2f695f8fadab5e3ad6f9d 565 Pfam PF04326 Putative DNA-binding domain 56 157 3.7E-6 T 31-10-2018 IPR007421 Schlafen, AAA domain GO:0005524 AF_0744 ef69d70c40b2f695f8fadab5e3ad6f9d 565 Pfam PF00009 Elongation factor Tu GTP binding domain 156 379 1.8E-39 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_0744 ef69d70c40b2f695f8fadab5e3ad6f9d 565 Pfam PF03143 Elongation factor Tu C-terminal domain 480 553 2.2E-8 T 31-10-2018 IPR004160 Translation elongation factor EFTu/EF1A, C-terminal AF_0744 ef69d70c40b2f695f8fadab5e3ad6f9d 565 SUPERFAMILY SSF50447 384 475 1.92E-21 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AF_0744 ef69d70c40b2f695f8fadab5e3ad6f9d 565 SUPERFAMILY SSF50465 477 564 4.11E-20 T 31-10-2018 IPR009001 Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal AF_0744 ef69d70c40b2f695f8fadab5e3ad6f9d 565 Gene3D G3DSA:3.40.50.300 149 381 4.2E-38 T 31-10-2018 AF_0744 ef69d70c40b2f695f8fadab5e3ad6f9d 565 Pfam PF03144 Elongation factor Tu domain 2 402 472 2.2E-14 T 31-10-2018 IPR004161 Translation elongation factor EFTu-like, domain 2 GO:0005525 AF_0744 ef69d70c40b2f695f8fadab5e3ad6f9d 565 Gene3D G3DSA:2.40.30.10 479 565 1.5E-7 T 31-10-2018 AF_0744 ef69d70c40b2f695f8fadab5e3ad6f9d 565 SUPERFAMILY SSF52540 154 403 1.04E-38 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0744 ef69d70c40b2f695f8fadab5e3ad6f9d 565 PRINTS PR00315 GTP-binding elongation factor signature 160 173 1.1E-6 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_0744 ef69d70c40b2f695f8fadab5e3ad6f9d 565 PRINTS PR00315 GTP-binding elongation factor signature 299 308 1.1E-6 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_0744 ef69d70c40b2f695f8fadab5e3ad6f9d 565 PRINTS PR00315 GTP-binding elongation factor signature 202 210 1.1E-6 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_0744 ef69d70c40b2f695f8fadab5e3ad6f9d 565 PRINTS PR00315 GTP-binding elongation factor signature 245 255 1.1E-6 T 31-10-2018 IPR000795 Transcription factor, GTP-binding domain GO:0003924|GO:0005525 AF_1481 bfb3a26a97b6851b9b4f55977cfd7b0d 69 Hamap MF_00794 Putative antitoxin . 1 69 15.123 T 31-10-2018 IPR003847 Putative antitoxin AF_1481 bfb3a26a97b6851b9b4f55977cfd7b0d 69 Pfam PF02697 Putative antitoxin 2 64 5.7E-22 T 31-10-2018 IPR003847 Putative antitoxin AF_1481 bfb3a26a97b6851b9b4f55977cfd7b0d 69 ProDom PD188822 UPF0330 AF1997 ST1125.1 AF1689 AF1478 C1_0043 PYRAB04040 PF1222 MM2475 MA1514 2 65 5.0E-28 T 31-10-2018 IPR003847 Putative antitoxin AF_0742 14b6a19f00d60495480961cc979e9233 360 SUPERFAMILY SSF56747 27 356 2.83E-82 T 31-10-2018 AF_0742 14b6a19f00d60495480961cc979e9233 360 Hamap MF_00700 DNA primase small subunit PriS [priS]. 30 354 30.408 T 31-10-2018 IPR023639 DNA primase small subunit PriS GO:0003896 AF_0742 14b6a19f00d60495480961cc979e9233 360 TIGRFAM TIGR00335 primase_sml: putative DNA primase, eukaryotic-type, small subunit 21 315 5.8E-114 T 31-10-2018 IPR014052 DNA primase, small subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 AF_0742 14b6a19f00d60495480961cc979e9233 360 Pfam PF01896 DNA primase small subunit 120 297 3.5E-34 T 31-10-2018 IPR002755 DNA primase, small subunit GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 AF_1247 dcbfb8e375dff80c6611508723f39a51 405 Pfam PF01938 TRAM domain 343 399 4.5E-14 T 31-10-2018 IPR002792 TRAM domain AF_1247 dcbfb8e375dff80c6611508723f39a51 405 Pfam PF04055 Radical SAM superfamily 118 291 6.1E-26 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_1247 dcbfb8e375dff80c6611508723f39a51 405 Gene3D G3DSA:3.40.50.12160 3 103 8.3E-9 T 31-10-2018 IPR038135 Methylthiotransferase, N-terminal domain superfamily AF_1247 dcbfb8e375dff80c6611508723f39a51 405 Gene3D G3DSA:3.80.30.20 111 346 1.5E-80 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe AF_1247 dcbfb8e375dff80c6611508723f39a51 405 TIGRFAM TIGR00089 TIGR00089: radical SAM methylthiotransferase, MiaB/RimO family 11 397 1.6E-113 T 31-10-2018 IPR005839 Methylthiotransferase GO:0006400|GO:0016740|GO:0051539 AF_1247 dcbfb8e375dff80c6611508723f39a51 405 SUPERFAMILY SSF102114 104 340 6.8E-52 T 31-10-2018 AF_1247 dcbfb8e375dff80c6611508723f39a51 405 ProSitePatterns PS01278 Methylthiotransferase radical SAM domain signature. 118 138 - T 31-10-2018 IPR020612 Methylthiotransferase, conserved site GO:0051539 AF_1247 dcbfb8e375dff80c6611508723f39a51 405 TIGRFAM TIGR01578 MiaB-like-B: MiaB-like tRNA modifying enzyme, archaeal-type 11 399 7.3E-128 T 31-10-2018 IPR006466 MiaB-like tRNA modifying enzyme, archaeal-type Reactome: R-HSA-6782315 AF_1247 dcbfb8e375dff80c6611508723f39a51 405 Pfam PF00919 Uncharacterized protein family UPF0004 12 65 1.0E-8 T 31-10-2018 IPR013848 Methylthiotransferase, N-terminal GO:0051539 AF_1247 dcbfb8e375dff80c6611508723f39a51 405 SMART SM00729 114 332 2.1E-60 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AF_0874 97d85d053805df5d3d4d42065aa30384 59 ProDom PD005132 RIBOSOMAL RRNA-BINDING METAL-BINDING RNA-BINDING ZINC RIBONUCLEOPROTEIN ZINC-FINGER L37 60S L37E 9 51 2.0E-17 T 31-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0874 97d85d053805df5d3d4d42065aa30384 59 Gene3D G3DSA:2.20.25.30 1 57 8.0E-21 T 31-10-2018 IPR011331 Ribosomal protein L37ae/L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_0874 97d85d053805df5d3d4d42065aa30384 59 ProSitePatterns PS01077 Ribosomal protein L37e signature. 4 24 - T 31-10-2018 IPR018267 Ribosomal protein L37e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0874 97d85d053805df5d3d4d42065aa30384 59 Pfam PF01907 Ribosomal protein L37e 3 56 8.7E-22 T 31-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0874 97d85d053805df5d3d4d42065aa30384 59 Hamap MF_00547 50S ribosomal protein L37e [rpl37e]. 2 55 21.454 T 31-10-2018 IPR001569 Ribosomal protein L37e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0874 97d85d053805df5d3d4d42065aa30384 59 SUPERFAMILY SSF57829 1 56 3.84E-20 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AF_1728 82c751949e35eb4fe3ddd04fefb7a1f9 356 Gene3D G3DSA:3.40.50.2000 1 186 3.0E-34 T 31-10-2018 AF_1728 82c751949e35eb4fe3ddd04fefb7a1f9 356 Pfam PF13439 Glycosyltransferase Family 4 14 173 5.5E-24 T 31-10-2018 IPR028098 Glycosyltransferase subfamily 4-like, N-terminal domain Reactome: R-HSA-446193|Reactome: R-HSA-4549349 AF_1728 82c751949e35eb4fe3ddd04fefb7a1f9 356 SUPERFAMILY SSF53756 2 356 7.18E-87 T 31-10-2018 AF_1728 82c751949e35eb4fe3ddd04fefb7a1f9 356 Pfam PF00534 Glycosyl transferases group 1 174 332 2.1E-40 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 AF_1728 82c751949e35eb4fe3ddd04fefb7a1f9 356 Gene3D G3DSA:3.40.50.2000 187 346 8.2E-44 T 31-10-2018 AF_0238 e5000811017c96aed55d22bc59f47da1 325 SMART SM00359 237 311 7.0E-23 T 31-10-2018 IPR002478 PUA domain GO:0003723 AF_0238 e5000811017c96aed55d22bc59f47da1 325 Hamap MF_01081 Probable tRNA pseudouridine synthase B [truB]. 27 311 52.416 T 31-10-2018 IPR026326 Probable tRNA pseudouridine synthase B, archaeal GO:0006396 AF_0238 e5000811017c96aed55d22bc59f47da1 325 TIGRFAM TIGR00425 CBF5: putative rRNA pseudouridine synthase 2 321 7.3E-174 T 31-10-2018 IPR004802 tRNA pseudouridine synthase B family GO:0006396 Reactome: R-HSA-171319|Reactome: R-HSA-6790901 AF_0238 e5000811017c96aed55d22bc59f47da1 325 Gene3D G3DSA:2.30.130.70 11 318 1.3E-142 T 31-10-2018 AF_0238 e5000811017c96aed55d22bc59f47da1 325 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 235 303 2.5E-7 T 31-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 AF_0238 e5000811017c96aed55d22bc59f47da1 325 Pfam PF01509 TruB family pseudouridylate synthase (N terminal domain) 54 167 7.6E-24 T 31-10-2018 IPR002501 Pseudouridine synthase II, N-terminal GO:0006396 AF_0238 e5000811017c96aed55d22bc59f47da1 325 Gene3D G3DSA:3.30.2350.10 27 229 1.3E-142 T 31-10-2018 AF_0238 e5000811017c96aed55d22bc59f47da1 325 Pfam PF01472 PUA domain 237 309 3.0E-20 T 31-10-2018 IPR002478 PUA domain GO:0003723 AF_0238 e5000811017c96aed55d22bc59f47da1 325 Pfam PF16198 tRNA pseudouridylate synthase B C-terminal domain 168 232 1.1E-25 T 31-10-2018 IPR032819 tRNA pseudouridylate synthase B, C-terminal Reactome: R-HSA-171319|Reactome: R-HSA-6790901 AF_0238 e5000811017c96aed55d22bc59f47da1 325 Pfam PF08068 DKCLD (NUC011) domain 4 50 4.2E-17 T 31-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 AF_0238 e5000811017c96aed55d22bc59f47da1 325 SUPERFAMILY SSF88697 236 318 7.73E-22 T 31-10-2018 IPR015947 PUA-like superfamily AF_0238 e5000811017c96aed55d22bc59f47da1 325 SMART SM01136 2 50 6.7E-24 T 31-10-2018 IPR012960 Dyskerin-like Reactome: R-HSA-171319|Reactome: R-HSA-6790901 AF_0238 e5000811017c96aed55d22bc59f47da1 325 SUPERFAMILY SSF55120 4 232 8.63E-74 T 31-10-2018 IPR020103 Pseudouridine synthase, catalytic domain superfamily GO:0001522|GO:0003723|GO:0009451|GO:0009982 AF_0490 f46af489aa3878d779a6fe476bd1c163 246 SMART SM00948 8 30 2.7E-11 T 31-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AF_0490 f46af489aa3878d779a6fe476bd1c163 246 Pfam PF10584 Proteasome subunit A N-terminal signature 8 30 3.8E-14 T 31-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AF_0490 f46af489aa3878d779a6fe476bd1c163 246 TIGRFAM TIGR03633 arc_protsome_A: proteasome endopeptidase complex, archaeal, alpha subunit 6 234 1.5E-112 T 31-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 AF_0490 f46af489aa3878d779a6fe476bd1c163 246 Gene3D G3DSA:3.60.20.10 1 246 1.5E-92 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AF_0490 f46af489aa3878d779a6fe476bd1c163 246 ProSitePatterns PS00388 Proteasome alpha-type subunits signature. 8 30 - T 31-10-2018 IPR000426 Proteasome alpha-subunit, N-terminal domain GO:0004175|GO:0006511|GO:0019773 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AF_0490 f46af489aa3878d779a6fe476bd1c163 246 Hamap MF_00289_A Proteasome subunit alpha [prcA]. 3 233 49.581 T 31-10-2018 IPR019982 Proteasome alpha subunit, archaeal GO:0004298|GO:0005839|GO:0051603 AF_0490 f46af489aa3878d779a6fe476bd1c163 246 Pfam PF00227 Proteasome subunit 31 214 1.6E-63 T 31-10-2018 IPR001353 Proteasome, subunit alpha/beta GO:0004298|GO:0005839|GO:0051603 Reactome: R-HSA-1169091|Reactome: R-HSA-1234176|Reactome: R-HSA-1236974|Reactome: R-HSA-1236978|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-187577|Reactome: R-HSA-195253|Reactome: R-HSA-202424|Reactome: R-HSA-211733|Reactome: R-HSA-2467813|Reactome: R-HSA-2871837|Reactome: R-HSA-349425|Reactome: R-HSA-350562|Reactome: R-HSA-382556|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689880|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69481|Reactome: R-HSA-69601|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-9010553|Reactome: R-HSA-9020702|Reactome: R-HSA-9604323|Reactome: R-HSA-983168 AF_0490 f46af489aa3878d779a6fe476bd1c163 246 SUPERFAMILY SSF56235 6 238 5.9E-83 T 31-10-2018 IPR029055 Nucleophile aminohydrolases, N-terminal AF_0404 94f9d7072545767eb6442213c5c547ed 293 Hamap MF_01286 Digeranylgeranylglyceryl phosphate synthase. 13 293 19.915 T 31-10-2018 IPR023547 Digeranylgeranylglyceryl phosphate synthase GO:0000287|GO:0005886|GO:0008654|GO:0047295 KEGG: 00564+2.5.1.42|MetaCyc: PWY-6349 AF_0404 94f9d7072545767eb6442213c5c547ed 293 Pfam PF01040 UbiA prenyltransferase family 32 273 1.4E-40 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AF_0404 94f9d7072545767eb6442213c5c547ed 293 Gene3D G3DSA:1.10.357.140 19 176 4.6E-17 T 31-10-2018 AF_1743 f9fabd3b22705ca0b2373492d7ddef2c 191 Gene3D G3DSA:1.10.10.10 1 57 3.2E-15 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1743 f9fabd3b22705ca0b2373492d7ddef2c 191 Pfam PF13412 Winged helix-turn-helix DNA-binding 8 53 3.3E-15 T 31-10-2018 AF_1743 f9fabd3b22705ca0b2373492d7ddef2c 191 SMART SM00344 7 109 6.2E-27 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AF_1743 f9fabd3b22705ca0b2373492d7ddef2c 191 ProSitePatterns PS00519 AsnC-type HTH domain signature. 25 51 - T 31-10-2018 IPR019885 Transcription regulator HTH, AsnC-type, conserved site AF_1743 f9fabd3b22705ca0b2373492d7ddef2c 191 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 7 23 2.5E-12 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_1743 f9fabd3b22705ca0b2373492d7ddef2c 191 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 34 53 2.5E-12 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_1743 f9fabd3b22705ca0b2373492d7ddef2c 191 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 23 34 2.5E-12 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_1743 f9fabd3b22705ca0b2373492d7ddef2c 191 SUPERFAMILY SSF46785 2 73 1.6E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0853 71fae3ad1b1e0fd67a12e5c7f580dfae 317 Gene3D G3DSA:3.30.70.3130 10 106 2.2E-15 T 31-10-2018 AF_0853 71fae3ad1b1e0fd67a12e5c7f580dfae 317 Pfam PF01189 16S rRNA methyltransferase RsmB/F 112 315 7.2E-50 T 31-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 AF_0853 71fae3ad1b1e0fd67a12e5c7f580dfae 317 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 28 107 5.7E-17 T 31-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 AF_0853 71fae3ad1b1e0fd67a12e5c7f580dfae 317 SUPERFAMILY SSF53335 33 316 1.7E-60 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_0853 71fae3ad1b1e0fd67a12e5c7f580dfae 317 Gene3D G3DSA:3.40.50.150 110 317 1.2E-70 T 31-10-2018 AF_0853 71fae3ad1b1e0fd67a12e5c7f580dfae 317 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 93 107 4.6E-25 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AF_0853 71fae3ad1b1e0fd67a12e5c7f580dfae 317 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 188 200 4.6E-25 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AF_0853 71fae3ad1b1e0fd67a12e5c7f580dfae 317 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 122 132 4.6E-25 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AF_0853 71fae3ad1b1e0fd67a12e5c7f580dfae 317 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 238 254 4.6E-25 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AF_0853 71fae3ad1b1e0fd67a12e5c7f580dfae 317 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 299 316 4.6E-25 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AF_0853 71fae3ad1b1e0fd67a12e5c7f580dfae 317 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 50 316 1.7E-120 T 31-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 AF_0107 b00f4255722d9ca4ef631cbfdfc0f684 153 SUPERFAMILY SSF54893 3 98 9.55E-34 T 31-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily AF_0107 b00f4255722d9ca4ef631cbfdfc0f684 153 Hamap MF_00002 Aspartate carbamoyltransferase regulatory chain [pyrI]. 1 152 32.65 T 31-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 AF_0107 b00f4255722d9ca4ef631cbfdfc0f684 153 Gene3D G3DSA:2.30.30.20 98 149 4.2E-15 T 31-10-2018 AF_0107 b00f4255722d9ca4ef631cbfdfc0f684 153 SUPERFAMILY SSF57825 99 146 7.06E-11 T 31-10-2018 IPR036792 Aspartate carbamoyltransferase regulatory subunit, C-terminal domain superfamily AF_0107 b00f4255722d9ca4ef631cbfdfc0f684 153 Pfam PF01948 Aspartate carbamoyltransferase regulatory chain, allosteric domain 5 95 3.0E-33 T 31-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal AF_0107 b00f4255722d9ca4ef631cbfdfc0f684 153 Gene3D G3DSA:3.30.70.140 1 96 2.8E-36 T 31-10-2018 IPR036793 Aspartate carbamoyltransferase regulatory subunit, N-terminal domain superfamily AF_0107 b00f4255722d9ca4ef631cbfdfc0f684 153 TIGRFAM TIGR00240 ATCase_reg: aspartate carbamoyltransferase, regulatory subunit 2 152 1.2E-73 T 31-10-2018 IPR002801 Aspartate transcarbamylase regulatory subunit GO:0006207|GO:0009347 AF_0107 b00f4255722d9ca4ef631cbfdfc0f684 153 Pfam PF02748 Aspartate carbamoyltransferase regulatory chain, metal binding domain 101 147 2.1E-15 T 31-10-2018 IPR020542 Aspartate carbamoyltransferase regulatory subunit, C-terminal AF_0107 b00f4255722d9ca4ef631cbfdfc0f684 153 ProDom PD006194 REGULATORY ASPARTATE CARBAMOYLTRANSFERASE CHAIN METAL-BINDING ZINC PYRIMIDINE BIOSYNTHESIS SUBUNIT TRANSFERASE 6 96 1.0E-45 T 31-10-2018 IPR020545 Aspartate carbamoyltransferase regulatory subunit, N-terminal AF_0437 69eb8da5e4f7430a143087db1e4afd93 131 Gene3D G3DSA:1.10.12.20 2 61 3.1E-7 T 31-10-2018 AF_0437 69eb8da5e4f7430a143087db1e4afd93 131 SUPERFAMILY SSF50249 6 122 6.0E-22 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0437 69eb8da5e4f7430a143087db1e4afd93 131 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 23 54 9.4E-7 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AF_0437 69eb8da5e4f7430a143087db1e4afd93 131 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 58 114 1.5E-9 T 31-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AF_0212 0e6570e2764d8da73848b6251b417c4a 404 Hamap MF_01024 Histidinol dehydrogenase [hisD]. 2 401 40.21 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AF_0212 0e6570e2764d8da73848b6251b417c4a 404 PIRSF PIRSF000099 1 404 3.5E-171 T 31-10-2018 IPR022695 Histidinol dehydrogenase, monofunctional GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AF_0212 0e6570e2764d8da73848b6251b417c4a 404 Pfam PF00815 Histidinol dehydrogenase 8 401 2.4E-154 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AF_0212 0e6570e2764d8da73848b6251b417c4a 404 Gene3D G3DSA:3.40.50.1980 219 323 1.5E-110 T 31-10-2018 AF_0212 0e6570e2764d8da73848b6251b417c4a 404 Gene3D G3DSA:3.40.50.1980 18 217 1.5E-110 T 31-10-2018 AF_0212 0e6570e2764d8da73848b6251b417c4a 404 PRINTS PR00083 Histidinol dehydrogenase signature 121 147 4.6E-92 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AF_0212 0e6570e2764d8da73848b6251b417c4a 404 PRINTS PR00083 Histidinol dehydrogenase signature 156 182 4.6E-92 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AF_0212 0e6570e2764d8da73848b6251b417c4a 404 PRINTS PR00083 Histidinol dehydrogenase signature 294 319 4.6E-92 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AF_0212 0e6570e2764d8da73848b6251b417c4a 404 PRINTS PR00083 Histidinol dehydrogenase signature 237 256 4.6E-92 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AF_0212 0e6570e2764d8da73848b6251b417c4a 404 PRINTS PR00083 Histidinol dehydrogenase signature 335 353 4.6E-92 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AF_0212 0e6570e2764d8da73848b6251b417c4a 404 PRINTS PR00083 Histidinol dehydrogenase signature 186 211 4.6E-92 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AF_0212 0e6570e2764d8da73848b6251b417c4a 404 PRINTS PR00083 Histidinol dehydrogenase signature 20 44 4.6E-92 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AF_0212 0e6570e2764d8da73848b6251b417c4a 404 PRINTS PR00083 Histidinol dehydrogenase signature 215 236 4.6E-92 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AF_0212 0e6570e2764d8da73848b6251b417c4a 404 TIGRFAM TIGR00069 hisD: histidinol dehydrogenase 20 400 5.1E-155 T 31-10-2018 IPR012131 Histidinol dehydrogenase GO:0000105|GO:0004399|GO:0008270|GO:0051287|GO:0055114 KEGG: 00340+1.1.1.23 AF_0212 0e6570e2764d8da73848b6251b417c4a 404 SUPERFAMILY SSF53720 13 401 6.08E-72 T 31-10-2018 IPR016161 Aldehyde/histidinol dehydrogenase GO:0016491|GO:0055114 AF_0212 0e6570e2764d8da73848b6251b417c4a 404 ProSitePatterns PS00611 Histidinol dehydrogenase signature. 215 247 - T 31-10-2018 IPR001692 Histidinol dehydrogenase, conserved site GO:0000105|GO:0004399|GO:0055114 KEGG: 00340+1.1.1.23 AF_0419 df0d1d23c5f1f75f7f9c70f8ea214e09 246 SUPERFAMILY SSF51366 8 243 2.17E-24 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AF_0419 df0d1d23c5f1f75f7f9c70f8ea214e09 246 Gene3D G3DSA:3.20.20.70 21 245 8.4E-6 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0419 df0d1d23c5f1f75f7f9c70f8ea214e09 246 ProDom PD011184 BTPA I PHOTOSYSTEM BIOGENESIS ASSEMBLY SGCQ TRIPHOSPHATASE NUCLEOSIDE PAE3553 ENZYME 23 189 1.0E-79 T 31-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family AF_0419 df0d1d23c5f1f75f7f9c70f8ea214e09 246 PIRSF PIRSF005956 1 246 5.9E-91 T 31-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family AF_0419 df0d1d23c5f1f75f7f9c70f8ea214e09 246 TIGRFAM TIGR00259 thylakoid_BtpA: membrane complex biogenesis protein, BtpA family 2 244 2.8E-116 T 31-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family AF_0419 df0d1d23c5f1f75f7f9c70f8ea214e09 246 Pfam PF03437 BtpA family 1 245 5.3E-112 T 31-10-2018 IPR005137 Membrane complex biogenesis protein, BtpA family AF_0445 aa5b6eb6a1c73dc812b3ca04b823becf 161 Pfam PF03692 Putative zinc- or iron-chelating domain 12 109 8.3E-13 T 31-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein AF_2308 2df3704c9db1cb4fb225b1ec431c5316 397 PRINTS PR00758 Arsenical pump membrane protein signature 99 123 7.7E-6 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AF_2308 2df3704c9db1cb4fb225b1ec431c5316 397 PRINTS PR00758 Arsenical pump membrane protein signature 172 195 7.7E-6 T 31-10-2018 IPR000802 Arsenical pump membrane protein, ArsB GO:0015105|GO:0015700|GO:0016021 AF_2308 2df3704c9db1cb4fb225b1ec431c5316 397 Pfam PF03600 Citrate transporter 22 344 2.3E-39 T 31-10-2018 IPR004680 Citrate transporter-like domain GO:0016021|GO:0055085 Reactome: R-HSA-5662702 AF_1853 9755da6e0b5647ce358c9986e1cb7b57 113 SMART SM00418 22 92 0.0071 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_1853 9755da6e0b5647ce358c9986e1cb7b57 113 Gene3D G3DSA:1.10.10.10 16 99 6.2E-11 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1853 9755da6e0b5647ce358c9986e1cb7b57 113 SUPERFAMILY SSF46785 22 100 6.37E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1853 9755da6e0b5647ce358c9986e1cb7b57 113 Pfam PF01022 Bacterial regulatory protein, arsR family 33 74 7.1E-9 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_0666 2f947ae536bc33c6b41749565b443444 105 Pfam PF02001 Protein of unknown function DUF134 8 104 4.7E-43 T 31-10-2018 IPR002852 Uncharacterised protein family UPF0251 AF_0666 2f947ae536bc33c6b41749565b443444 105 Hamap MF_00674 UPF0251 protein . 9 104 19.409 T 31-10-2018 IPR002852 Uncharacterised protein family UPF0251 AF_0666 2f947ae536bc33c6b41749565b443444 105 Gene3D G3DSA:1.10.10.10 40 89 5.1E-9 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0666 2f947ae536bc33c6b41749565b443444 105 SUPERFAMILY SSF88659 44 86 2.24E-7 T 31-10-2018 IPR013324 RNA polymerase sigma factor, region 3/4-like AF_0638 c10a6a1918c2c59fc1e17d3ba9cc16ac 235 SMART SM00382 31 201 8.1E-20 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0638 c10a6a1918c2c59fc1e17d3ba9cc16ac 235 Pfam PF00005 ABC transporter 22 153 2.0E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0638 c10a6a1918c2c59fc1e17d3ba9cc16ac 235 ProSitePatterns PS00211 ABC transporters family signature. 125 139 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_0638 c10a6a1918c2c59fc1e17d3ba9cc16ac 235 Gene3D G3DSA:3.40.50.300 2 233 1.5E-65 T 31-10-2018 AF_0638 c10a6a1918c2c59fc1e17d3ba9cc16ac 235 SUPERFAMILY SSF52540 7 227 1.5E-66 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1984 c115dc7ce2939279554395cefdb4c791 139 SMART SM00529 31 127 3.6E-36 T 31-10-2018 IPR022689 Iron dependent repressor GO:0003700|GO:0006355|GO:0046914 AF_1984 c115dc7ce2939279554395cefdb4c791 139 Gene3D G3DSA:1.10.10.10 6 139 8.7E-26 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1984 c115dc7ce2939279554395cefdb4c791 139 Pfam PF02742 Iron dependent repressor, metal binding and dimerisation domain 71 135 9.7E-13 T 31-10-2018 IPR001367 Iron dependent repressor, metal binding and dimerisation domain GO:0046914|GO:0046983 AF_1984 c115dc7ce2939279554395cefdb4c791 139 SUPERFAMILY SSF46785 20 70 2.94E-6 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1984 c115dc7ce2939279554395cefdb4c791 139 SUPERFAMILY SSF47979 71 135 1.96E-12 T 31-10-2018 IPR036421 Iron dependent repressor, metal binding and dimerisation domain superfamily GO:0046914|GO:0046983 AF_1984 c115dc7ce2939279554395cefdb4c791 139 Pfam PF01325 Iron dependent repressor, N-terminal DNA binding domain 7 67 3.2E-22 T 31-10-2018 IPR022687 DTXR-type HTH domain GO:0003677 AF_1398 9b65b2d644eaf5496e797eaf778246b7 806 TIGRFAM TIGR04213 PGF_pre_PGF: PGF-pre-PGF domain 371 449 5.1E-11 T 31-10-2018 IPR026453 PGF-pre-PGF domain AF_1398 9b65b2d644eaf5496e797eaf778246b7 806 SMART SM00089 237 319 5.6E-29 T 31-10-2018 IPR022409 PKD/Chitinase domain AF_1398 9b65b2d644eaf5496e797eaf778246b7 806 Gene3D G3DSA:1.50.10.20 592 734 8.5E-23 T 31-10-2018 AF_1398 9b65b2d644eaf5496e797eaf778246b7 806 Gene3D G3DSA:1.50.10.20 412 591 1.5E-14 T 31-10-2018 AF_1398 9b65b2d644eaf5496e797eaf778246b7 806 Gene3D G3DSA:3.10.20.490 115 201 5.7E-5 T 31-10-2018 AF_1398 9b65b2d644eaf5496e797eaf778246b7 806 SUPERFAMILY SSF48239 457 605 1.36E-13 T 31-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid AF_1398 9b65b2d644eaf5496e797eaf778246b7 806 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 597 723 3.3E-8 T 31-10-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 AF_1398 9b65b2d644eaf5496e797eaf778246b7 806 Pfam PF13243 Squalene-hopene cyclase C-terminal domain 456 526 9.8E-7 T 31-10-2018 IPR032696 Squalene cyclase, C-terminal Reactome: R-HSA-191273|Reactome: R-HSA-2426168 AF_1398 9b65b2d644eaf5496e797eaf778246b7 806 Gene3D G3DSA:2.60.40.10 227 318 9.7E-26 T 31-10-2018 IPR013783 Immunoglobulin-like fold AF_1398 9b65b2d644eaf5496e797eaf778246b7 806 Pfam PF14478 Domain of unknown function (DUF4430) 124 200 1.9E-5 T 31-10-2018 IPR027954 Domain of unknown function DUF4430 Reactome: R-HSA-196741 AF_1398 9b65b2d644eaf5496e797eaf778246b7 806 Pfam PF00801 PKD domain 244 308 8.0E-18 T 31-10-2018 IPR000601 PKD domain AF_1398 9b65b2d644eaf5496e797eaf778246b7 806 SUPERFAMILY SSF49299 234 319 1.19E-23 T 31-10-2018 IPR035986 PKD domain superfamily AF_1398 9b65b2d644eaf5496e797eaf778246b7 806 SUPERFAMILY SSF48239 570 716 5.83E-26 T 31-10-2018 IPR008930 Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid AF_0639 da4cb61c798edea92a07a84a8678f77b 248 Gene3D G3DSA:1.10.3720.10 43 244 1.7E-21 T 31-10-2018 IPR035906 MetI-like superfamily AF_0639 da4cb61c798edea92a07a84a8678f77b 248 SUPERFAMILY SSF161098 46 236 1.01E-22 T 31-10-2018 IPR035906 MetI-like superfamily AF_0639 da4cb61c798edea92a07a84a8678f77b 248 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 69 242 8.1E-13 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AF_1997 45902556eabc39f6c299aa58be392d66 73 Pfam PF02697 Putative antitoxin 3 67 1.2E-22 T 31-10-2018 IPR003847 Putative antitoxin AF_1997 45902556eabc39f6c299aa58be392d66 73 ProDom PD188822 UPF0330 AF1997 ST1125.1 AF1689 AF1478 C1_0043 PYRAB04040 PF1222 MM2475 MA1514 3 53 7.0E-22 T 31-10-2018 IPR003847 Putative antitoxin AF_1997 45902556eabc39f6c299aa58be392d66 73 Hamap MF_00794 Putative antitoxin . 2 70 17.617 T 31-10-2018 IPR003847 Putative antitoxin AF_1940 67df3fd76cb28e3fcb330571dc81f78d 765 Pfam PF00586 AIR synthase related protein, N-terminal domain 99 221 4.1E-20 T 31-10-2018 IPR016188 PurM-like, N-terminal domain AF_1940 67df3fd76cb28e3fcb330571dc81f78d 765 Pfam PF00586 AIR synthase related protein, N-terminal domain 478 595 8.7E-14 T 31-10-2018 IPR016188 PurM-like, N-terminal domain AF_1940 67df3fd76cb28e3fcb330571dc81f78d 765 Pfam PF02769 AIR synthase related protein, C-terminal domain 610 737 1.9E-15 T 31-10-2018 IPR010918 PurM-like, C-terminal domain AF_1940 67df3fd76cb28e3fcb330571dc81f78d 765 Pfam PF02769 AIR synthase related protein, C-terminal domain 234 388 2.1E-36 T 31-10-2018 IPR010918 PurM-like, C-terminal domain AF_1940 67df3fd76cb28e3fcb330571dc81f78d 765 PIRSF PIRSF001587 18 765 1.4E-221 T 31-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AF_1940 67df3fd76cb28e3fcb330571dc81f78d 765 SUPERFAMILY SSF55326 428 603 3.27E-49 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AF_1940 67df3fd76cb28e3fcb330571dc81f78d 765 Gene3D G3DSA:3.30.1330.10 415 599 1.9E-50 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AF_1940 67df3fd76cb28e3fcb330571dc81f78d 765 SUPERFAMILY SSF56042 233 454 1.5E-53 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AF_1940 67df3fd76cb28e3fcb330571dc81f78d 765 Gene3D G3DSA:3.90.650.10 220 404 6.0E-57 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AF_1940 67df3fd76cb28e3fcb330571dc81f78d 765 SUPERFAMILY SSF56042 610 761 1.17E-26 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AF_1940 67df3fd76cb28e3fcb330571dc81f78d 765 Gene3D G3DSA:1.10.8.750 7 65 8.5E-11 T 31-10-2018 AF_1940 67df3fd76cb28e3fcb330571dc81f78d 765 Gene3D G3DSA:3.90.650.10 605 765 8.7E-28 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AF_1940 67df3fd76cb28e3fcb330571dc81f78d 765 Hamap MF_00420 Phosphoribosylformylglycinamidine synthase subunit PurL [purL]. 1 765 234.947 T 31-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AF_1940 67df3fd76cb28e3fcb330571dc81f78d 765 Gene3D G3DSA:3.30.1330.10 66 219 8.2E-52 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AF_1940 67df3fd76cb28e3fcb330571dc81f78d 765 SUPERFAMILY SSF55326 39 227 2.3E-48 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AF_1940 67df3fd76cb28e3fcb330571dc81f78d 765 TIGRFAM TIGR01736 FGAM_synth_II: phosphoribosylformylglycinamidine synthase II 35 764 5.6E-294 T 31-10-2018 IPR010074 Phosphoribosylformylglycinamidine subunit PurL GO:0004642|GO:0005737|GO:0006189 KEGG: 00230+6.3.5.3|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AF_0144 c4d3413f39c55ce6c1a73b7623b11260 126 SUPERFAMILY SSF49503 11 126 3.38E-25 T 31-10-2018 IPR008972 Cupredoxin AF_0144 c4d3413f39c55ce6c1a73b7623b11260 126 Gene3D G3DSA:2.60.40.420 22 125 4.4E-25 T 31-10-2018 IPR008972 Cupredoxin AF_0144 c4d3413f39c55ce6c1a73b7623b11260 126 ProSitePatterns PS00078 CO II and nitrous oxide reductase dinuclear copper centers signature. 71 119 - T 31-10-2018 IPR001505 Copper centre Cu(A) GO:0005507 Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AF_0144 c4d3413f39c55ce6c1a73b7623b11260 126 Pfam PF13473 Cupredoxin-like domain 8 125 1.8E-13 T 31-10-2018 IPR028096 EfeO-type cupredoxin-like domain AF_0852 37d5fe5d1c167421293e644cad8f0b1a 451 ProSitePatterns PS00096 Serine hydroxymethyltransferase pyridoxal-phosphate attachment site. 244 260 - T 31-10-2018 IPR019798 Serine hydroxymethyltransferase, pyridoxal phosphate binding site GO:0030170 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AF_0852 37d5fe5d1c167421293e644cad8f0b1a 451 Pfam PF00464 Serine hydroxymethyltransferase 34 408 2.9E-84 T 31-10-2018 IPR039429 Serine hydroxymethyltransferase-like domain KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AF_0852 37d5fe5d1c167421293e644cad8f0b1a 451 PIRSF PIRSF000412 9 447 9.7E-160 T 31-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AF_0852 37d5fe5d1c167421293e644cad8f0b1a 451 Hamap MF_00051 Serine hydroxymethyltransferase [glyA]. 27 436 43.334 T 31-10-2018 IPR001085 Serine hydroxymethyltransferase GO:0004372|GO:0019264|GO:0030170|GO:0035999 KEGG: 00260+2.1.2.1|KEGG: 00460+2.1.2.1|KEGG: 00630+2.1.2.1|KEGG: 00670+2.1.2.1|KEGG: 00680+2.1.2.1|MetaCyc: PWY-1622|MetaCyc: PWY-181|MetaCyc: PWY-2161|MetaCyc: PWY-2201|MetaCyc: PWY-3661|MetaCyc: PWY-3661-1|MetaCyc: PWY-3841|MetaCyc: PWY-5497|Reactome: R-HSA-196757 AF_0852 37d5fe5d1c167421293e644cad8f0b1a 451 Gene3D G3DSA:3.40.640.10 62 300 1.7E-89 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AF_0852 37d5fe5d1c167421293e644cad8f0b1a 451 Gene3D G3DSA:3.90.1150.10 301 451 2.1E-55 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AF_0852 37d5fe5d1c167421293e644cad8f0b1a 451 SUPERFAMILY SSF53383 34 435 5.25E-136 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AF_0904 be3ef8320f7732c64e5031ebf742259d 403 TIGRFAM TIGR01910 DapE-ArgE: peptidase, ArgE/DapE family 15 393 2.0E-78 T 31-10-2018 IPR010182 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase/Succinyl-diaminopimelate desuccinylase AF_0904 be3ef8320f7732c64e5031ebf742259d 403 Gene3D G3DSA:3.30.70.360 197 319 7.0E-70 T 31-10-2018 AF_0904 be3ef8320f7732c64e5031ebf742259d 403 Pfam PF01546 Peptidase family M20/M25/M40 86 396 1.7E-32 T 31-10-2018 IPR002933 Peptidase M20 GO:0016787 AF_0904 be3ef8320f7732c64e5031ebf742259d 403 SUPERFAMILY SSF53187 2 397 9.71E-53 T 31-10-2018 AF_0904 be3ef8320f7732c64e5031ebf742259d 403 SUPERFAMILY SSF55031 199 311 4.19E-14 T 31-10-2018 IPR036264 Bacterial exopeptidase dimerisation domain AF_0904 be3ef8320f7732c64e5031ebf742259d 403 Pfam PF07687 Peptidase dimerisation domain 193 297 1.2E-14 T 31-10-2018 IPR011650 Peptidase M20, dimerisation domain AF_0904 be3ef8320f7732c64e5031ebf742259d 403 Gene3D G3DSA:3.40.630.10 19 388 7.0E-70 T 31-10-2018 AF_1085 512e84244b79d2843d71c9b36d1ed4ad 56 Gene3D G3DSA:3.40.50.1010 3 44 7.6E-7 T 31-10-2018 AF_1085 512e84244b79d2843d71c9b36d1ed4ad 56 Pfam PF01850 PIN domain 2 35 5.0E-5 T 31-10-2018 IPR002716 PIN domain AF_1085 512e84244b79d2843d71c9b36d1ed4ad 56 SUPERFAMILY SSF88723 3 50 1.18E-10 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_2055 c09aac3376f45fc07d3d57890e32e121 172 Gene3D G3DSA:3.40.920.10 2 171 2.1E-35 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AF_2055 c09aac3376f45fc07d3d57890e32e121 172 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 166 1.9E-23 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AF_2055 c09aac3376f45fc07d3d57890e32e121 172 SUPERFAMILY SSF53323 2 169 3.14E-26 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AF_2055 c09aac3376f45fc07d3d57890e32e121 172 TIGRFAM TIGR02175 PorC_KorC: 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate family 2 170 8.5E-36 T 31-10-2018 IPR011894 2-oxoacid:acceptor oxidoreductase, gamma subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0055114 AF_0706 dc2300d92c7e8e38afcda3da51f8315c 403 Pfam PF01940 Integral membrane protein DUF92 178 386 1.2E-47 T 31-10-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 AF_0706 dc2300d92c7e8e38afcda3da51f8315c 403 TIGRFAM TIGR00297 TIGR00297: TIGR00297 family protein 169 401 2.7E-101 T 31-10-2018 IPR002794 Protein of unknown function DUF92, TMEM19 GO:0016021 AF_0181 d715e4f5e739d53b6a58fbaa2891ef5f 390 SUPERFAMILY SSF53383 15 380 3.32E-49 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AF_0181 d715e4f5e739d53b6a58fbaa2891ef5f 390 Gene3D G3DSA:3.40.640.10 24 282 1.4E-152 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AF_0181 d715e4f5e739d53b6a58fbaa2891ef5f 390 Pfam PF05889 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS 103 381 8.9E-27 T 31-10-2018 IPR008829 SepSecS/SepCysS family GO:0016740 Reactome: R-HSA-2408557 AF_0181 d715e4f5e739d53b6a58fbaa2891ef5f 390 Hamap MF_01675 O-phospho-L-seryl-tRNA:Cys-tRNA synthase. 1 385 57.548 T 31-10-2018 IPR013375 O-phosphoseryl-tRNA:Cys-tRNA synthase, archaea GO:0043766 KEGG: 00970+2.5.1.73|MetaCyc: PWY-6308 AF_0181 d715e4f5e739d53b6a58fbaa2891ef5f 390 Gene3D G3DSA:3.90.1150.10 13 382 1.4E-152 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AF_0181 d715e4f5e739d53b6a58fbaa2891ef5f 390 TIGRFAM TIGR02539 SepCysS: O-phospho-L-seryl-tRNA:Cys-tRNA synthase 13 384 3.0E-154 T 31-10-2018 IPR013375 O-phosphoseryl-tRNA:Cys-tRNA synthase, archaea GO:0043766 KEGG: 00970+2.5.1.73|MetaCyc: PWY-6308 AF_1570 764961839127692be7d028c1864059ff 207 TIGRFAM TIGR04449 halocin_C8_dom: halocin C8-like bacteriocin domain 140 207 1.2E-16 T 31-10-2018 IPR031033 Halocin C8-like bacteriocin domain AF_1234 76a67eb8fa0824c55dd9fc8ace5004d9 137 Pfam PF00293 NUDIX domain 13 124 2.9E-20 T 31-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AF_1234 76a67eb8fa0824c55dd9fc8ace5004d9 137 Gene3D G3DSA:3.90.79.10 1 127 6.4E-41 T 31-10-2018 AF_1234 76a67eb8fa0824c55dd9fc8ace5004d9 137 SUPERFAMILY SSF55811 4 122 1.0E-32 T 31-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AF_1234 76a67eb8fa0824c55dd9fc8ace5004d9 137 ProSitePatterns PS00893 Nudix box signature. 37 58 - T 31-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AF_1234 76a67eb8fa0824c55dd9fc8ace5004d9 137 PRINTS PR00502 NUDIX hydrolase family signature 46 61 7.6E-7 T 31-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AF_1234 76a67eb8fa0824c55dd9fc8ace5004d9 137 PRINTS PR00502 NUDIX hydrolase family signature 32 46 7.6E-7 T 31-10-2018 IPR020476 NUDIX hydrolase Reactome: R-HSA-2393930 AF_0284 152857153de4ef4a2f195da68318527b 165 SUPERFAMILY SSF50249 28 158 4.97E-39 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0284 152857153de4ef4a2f195da68318527b 165 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 88 148 1.5E-15 T 31-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AF_0284 152857153de4ef4a2f195da68318527b 165 Gene3D G3DSA:1.10.12.20 20 91 7.9E-18 T 31-10-2018 AF_0284 152857153de4ef4a2f195da68318527b 165 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 52 87 6.2E-14 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AF_0375 44132bc220260e72852e7cac4572a5af 207 Gene3D G3DSA:2.40.50.140 112 201 4.6E-6 T 31-10-2018 AF_0375 44132bc220260e72852e7cac4572a5af 207 Gene3D G3DSA:1.20.1440.150 1 90 3.8E-8 T 31-10-2018 AF_1009 491726064a606265660af72dd5cefd9b 247 SUPERFAMILY SSF46785 2 98 1.63E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1009 491726064a606265660af72dd5cefd9b 247 Gene3D G3DSA:1.10.10.10 1 101 2.4E-27 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1009 491726064a606265660af72dd5cefd9b 247 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 8 74 6.3E-26 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal AF_1925 bd898ab11bd6d62980d0e38dab1eceb6 331 Pfam PF00297 Ribosomal protein L3 2 330 2.0E-97 T 31-10-2018 IPR000597 Ribosomal protein L3 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1925 bd898ab11bd6d62980d0e38dab1eceb6 331 ProSitePatterns PS00474 Ribosomal protein L3 signature. 186 209 - T 31-10-2018 IPR019926 Ribosomal protein L3, conserved site AF_1925 bd898ab11bd6d62980d0e38dab1eceb6 331 Gene3D G3DSA:4.10.960.10 5 250 4.6E-129 T 31-10-2018 AF_1925 bd898ab11bd6d62980d0e38dab1eceb6 331 Hamap MF_01325_A 50S ribosomal protein L3 [rplC]. 1 329 52.4 T 31-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1925 bd898ab11bd6d62980d0e38dab1eceb6 331 Gene3D G3DSA:3.30.1430.10 77 181 4.6E-129 T 31-10-2018 AF_1925 bd898ab11bd6d62980d0e38dab1eceb6 331 Gene3D G3DSA:2.40.30.10 38 311 4.6E-129 T 31-10-2018 AF_1925 bd898ab11bd6d62980d0e38dab1eceb6 331 TIGRFAM TIGR03626 L3_arch: ribosomal protein uL3 4 328 1.4E-158 T 31-10-2018 IPR019928 Ribosomal protein L3, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1925 bd898ab11bd6d62980d0e38dab1eceb6 331 SUPERFAMILY SSF50447 2 330 2.65E-102 T 31-10-2018 IPR009000 Translation protein, beta-barrel domain superfamily AF_1490 7235885408a65742db6a2a00286a99b4 215 Gene3D G3DSA:3.40.50.790 60 150 9.2E-72 T 31-10-2018 IPR016095 Ribosomal protein L1, 3-layer alpha/beta-sandwich AF_1490 7235885408a65742db6a2a00286a99b4 215 Hamap MF_01318_A 50S ribosomal protein L1 [rplA]. 4 215 38.313 T 31-10-2018 IPR023669 Ribosomal protein L1, archaea GO:0003723|GO:0003735|GO:0006412|GO:0015934 AF_1490 7235885408a65742db6a2a00286a99b4 215 PIRSF PIRSF002155 1 215 2.7E-71 T 31-10-2018 IPR002143 Ribosomal protein L1 GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1490 7235885408a65742db6a2a00286a99b4 215 Pfam PF00687 Ribosomal protein L1p/L10e family 19 210 1.7E-43 T 31-10-2018 IPR028364 Ribosomal protein L1/ribosomal biogenesis protein AF_1490 7235885408a65742db6a2a00286a99b4 215 Gene3D G3DSA:3.30.190.20 19 210 9.2E-72 T 31-10-2018 AF_1490 7235885408a65742db6a2a00286a99b4 215 ProSitePatterns PS01199 Ribosomal protein L1 signature. 115 134 - T 31-10-2018 IPR023673 Ribosomal protein L1, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1490 7235885408a65742db6a2a00286a99b4 215 SUPERFAMILY SSF56808 5 214 1.57E-60 T 31-10-2018 IPR023674 Ribosomal protein L1-like AF_2345 0604bb7ae4ebdf38b304ca47fbf282ca 162 Pfam PF06634 Protein of unknown function (DUF1156) 9 56 5.2E-16 T 31-10-2018 IPR009537 Domain of unknown function DUF1156 AF_2345 0604bb7ae4ebdf38b304ca47fbf282ca 162 Pfam PF03602 Conserved hypothetical protein 95 93 152 3.3E-5 T 31-10-2018 AF_2345 0604bb7ae4ebdf38b304ca47fbf282ca 162 Gene3D G3DSA:3.40.50.150 14 159 6.6E-9 T 31-10-2018 AF_2345 0604bb7ae4ebdf38b304ca47fbf282ca 162 SUPERFAMILY SSF53335 34 152 5.94E-16 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_1323 2d6383ced972cbe3b45ef9bdc77f2952 488 Pfam PF00282 Pyridoxal-dependent decarboxylase conserved domain 65 341 1.8E-18 T 31-10-2018 IPR002129 Pyridoxal phosphate-dependent decarboxylase GO:0016831|GO:0019752|GO:0030170 AF_1323 2d6383ced972cbe3b45ef9bdc77f2952 488 SUPERFAMILY SSF53383 36 432 9.38E-104 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AF_1323 2d6383ced972cbe3b45ef9bdc77f2952 488 Gene3D G3DSA:3.90.1150.10 37 423 1.5E-109 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AF_1323 2d6383ced972cbe3b45ef9bdc77f2952 488 Gene3D G3DSA:3.40.640.10 75 331 1.5E-109 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AF_0721 53fcc51c686849bff76b7976dfa0eb44 132 SUPERFAMILY SSF53800 2 122 3.92E-24 T 31-10-2018 AF_0721 53fcc51c686849bff76b7976dfa0eb44 132 Pfam PF01903 CbiX 10 117 3.9E-18 T 31-10-2018 IPR002762 Cobalamin (vitamin B12) biosynthesis CbiX GO:0009236|GO:0016852 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 AF_0721 53fcc51c686849bff76b7976dfa0eb44 132 Hamap MF_00785 Sirohydrochlorin cobaltochelatase [cbiX]. 2 124 24.916 T 31-10-2018 IPR023652 Sirohydrochlorin cobaltochelatase GO:0016852|GO:0050897 KEGG: 00860+4.99.1.3|MetaCyc: PWY-7377 AF_0721 53fcc51c686849bff76b7976dfa0eb44 132 Gene3D G3DSA:3.40.50.1400 1 132 1.1E-29 T 31-10-2018 AF_2209 1f5d57d174940c42f4d6ee01d2db8cf6 254 Pfam PF03029 Conserved hypothetical ATP binding protein 9 243 5.1E-67 T 31-10-2018 IPR004130 GPN-loop GTPase AF_2209 1f5d57d174940c42f4d6ee01d2db8cf6 254 Gene3D G3DSA:3.40.50.300 1 245 8.1E-60 T 31-10-2018 AF_2209 1f5d57d174940c42f4d6ee01d2db8cf6 254 SUPERFAMILY SSF52540 6 241 7.2E-39 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2045 716e1458166ee8b3769d8a167d0eaa4c 195 TIGRFAM TIGR00164 PS_decarb_rel: phosphatidylserine decarboxylase homolog 1 192 6.7E-80 T 31-10-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 AF_2045 716e1458166ee8b3769d8a167d0eaa4c 195 Pfam PF02666 Phosphatidylserine decarboxylase 34 186 2.2E-24 T 31-10-2018 IPR003817 Phosphatidylserine decarboxylase-related GO:0004609|GO:0008654 KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669|Reactome: R-HSA-1483213 AF_2045 716e1458166ee8b3769d8a167d0eaa4c 195 Hamap MF_00664 Phosphatidylserine decarboxylase proenzyme [psd]. 1 190 32.513 T 31-10-2018 IPR033175 Phosphatidylserine decarboxylase, archaeal-type KEGG: 00564+4.1.1.65|MetaCyc: PWY-5669 AF_0028 12a860e7a1b02eeb18cf3124d062937c 371 Hamap MF_01675 O-phospho-L-seryl-tRNA:Cys-tRNA synthase. 1 371 58.326 T 31-10-2018 IPR013375 O-phosphoseryl-tRNA:Cys-tRNA synthase, archaea GO:0043766 KEGG: 00970+2.5.1.73|MetaCyc: PWY-6308 AF_0028 12a860e7a1b02eeb18cf3124d062937c 371 Pfam PF05889 O-phosphoseryl-tRNA(Sec) selenium transferase, SepSecS 34 368 2.3E-100 T 31-10-2018 IPR008829 SepSecS/SepCysS family GO:0016740 Reactome: R-HSA-2408557 AF_0028 12a860e7a1b02eeb18cf3124d062937c 371 Gene3D G3DSA:3.90.1150.10 6 368 1.0E-184 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AF_0028 12a860e7a1b02eeb18cf3124d062937c 371 Gene3D G3DSA:3.40.640.10 18 269 1.0E-184 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AF_0028 12a860e7a1b02eeb18cf3124d062937c 371 SUPERFAMILY SSF53383 15 370 7.93E-65 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AF_0028 12a860e7a1b02eeb18cf3124d062937c 371 TIGRFAM TIGR02539 SepCysS: O-phospho-L-seryl-tRNA:Cys-tRNA synthase 3 370 3.2E-180 T 31-10-2018 IPR013375 O-phosphoseryl-tRNA:Cys-tRNA synthase, archaea GO:0043766 KEGG: 00970+2.5.1.73|MetaCyc: PWY-6308 AF_0980 206d492e239dba43a58894f355721397 218 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 38 214 2.1E-23 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AF_0980 206d492e239dba43a58894f355721397 218 Gene3D G3DSA:1.10.3720.10 15 211 3.8E-28 T 31-10-2018 IPR035906 MetI-like superfamily AF_0980 206d492e239dba43a58894f355721397 218 SUPERFAMILY SSF161098 19 200 3.53E-34 T 31-10-2018 IPR035906 MetI-like superfamily AF_0407 cda1c6507176b886090cde86ddec615c 169 PIRSF PIRSF006006 1 169 6.2E-80 T 31-10-2018 IPR007501 Protein of unknown function DUF531 AF_0407 cda1c6507176b886090cde86ddec615c 169 Pfam PF04407 Protein of unknown function (DUF531) 1 159 1.3E-71 T 31-10-2018 IPR007501 Protein of unknown function DUF531 AF_2381 adc911d7707cf9a371c6123c938eb20c 283 Gene3D G3DSA:3.30.70.20 62 113 1.8E-11 T 31-10-2018 AF_2381 adc911d7707cf9a371c6123c938eb20c 283 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 4 259 1.2E-20 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AF_2381 adc911d7707cf9a371c6123c938eb20c 283 Pfam PF00037 4Fe-4S binding domain 88 111 7.0E-6 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_2381 adc911d7707cf9a371c6123c938eb20c 283 Pfam PF00037 4Fe-4S binding domain 61 82 3.9E-5 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_2381 adc911d7707cf9a371c6123c938eb20c 283 SUPERFAMILY SSF54862 32 118 2.01E-18 T 31-10-2018 AF_2381 adc911d7707cf9a371c6123c938eb20c 283 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 95 106 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_2381 adc911d7707cf9a371c6123c938eb20c 283 SUPERFAMILY SSF52540 2 281 2.99E-27 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0640 e652c641789ab2148b61f9f17f032673 359 Gene3D G3DSA:3.40.190.10 325 359 5.2E-5 T 31-10-2018 AF_0640 e652c641789ab2148b61f9f17f032673 359 Gene3D G3DSA:3.40.190.10 31 221 2.4E-31 T 31-10-2018 AF_0640 e652c641789ab2148b61f9f17f032673 359 Pfam PF13379 NMT1-like family 231 357 2.7E-9 T 31-10-2018 AF_0640 e652c641789ab2148b61f9f17f032673 359 Pfam PF13379 NMT1-like family 44 142 7.8E-22 T 31-10-2018 AF_0640 e652c641789ab2148b61f9f17f032673 359 SUPERFAMILY SSF53850 20 190 5.29E-17 T 31-10-2018 AF_0640 e652c641789ab2148b61f9f17f032673 359 SUPERFAMILY SSF53850 232 355 2.35E-20 T 31-10-2018 AF_0640 e652c641789ab2148b61f9f17f032673 359 Gene3D G3DSA:3.40.190.10 227 324 4.7E-10 T 31-10-2018 AF_0529 345ae2b9ee8a2b4019785ab283d12d13 74 Gene3D G3DSA:1.10.10.10 1 73 9.1E-9 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0529 345ae2b9ee8a2b4019785ab283d12d13 74 SUPERFAMILY SSF46785 8 68 3.94E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0529 345ae2b9ee8a2b4019785ab283d12d13 74 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 15 63 9.5E-7 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal AF_2404 764dcadd41459e5ec715941815973187 96 SUPERFAMILY SSF46785 30 95 1.01E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_2404 764dcadd41459e5ec715941815973187 96 Pfam PF01022 Bacterial regulatory protein, arsR family 27 71 1.9E-12 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_2404 764dcadd41459e5ec715941815973187 96 Gene3D G3DSA:1.10.10.10 9 95 1.9E-11 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1755 773ce91254c13b232823c632f08f11c0 219 Pfam PF03591 AzlC protein 19 149 1.2E-35 T 31-10-2018 IPR011606 Branched-chain amino acid transport, permease AF_1532 e83d4c1bc7bbd8bf1d8d2f0524b90a0e 105 Gene3D G3DSA:2.30.30.240 5 77 6.3E-12 T 31-10-2018 AF_1532 e83d4c1bc7bbd8bf1d8d2f0524b90a0e 105 Pfam PF05239 PRC-barrel domain 7 76 1.5E-15 T 31-10-2018 IPR027275 PRC-barrel domain AF_1532 e83d4c1bc7bbd8bf1d8d2f0524b90a0e 105 SUPERFAMILY SSF50346 7 76 1.88E-14 T 31-10-2018 IPR011033 PRC-barrel-like superfamily AF_1187 1c541d109584e6f9780b40bd5dd612e6 449 SUPERFAMILY SSF118310 3 45 9.29E-13 T 31-10-2018 IPR035896 AN1-like Zinc finger AF_1187 1c541d109584e6f9780b40bd5dd612e6 449 Pfam PF01428 AN1-like Zinc finger 4 39 1.8E-11 T 31-10-2018 IPR000058 Zinc finger, AN1-type GO:0008270 AF_1187 1c541d109584e6f9780b40bd5dd612e6 449 Gene3D G3DSA:4.10.1110.10 1 45 5.2E-10 T 31-10-2018 IPR035896 AN1-like Zinc finger AF_1187 1c541d109584e6f9780b40bd5dd612e6 449 SMART SM00154 4 41 3.0E-18 T 31-10-2018 IPR000058 Zinc finger, AN1-type GO:0008270 AF_1957 67d96a90bdd0515b5e7b65543ca055b3 329 Gene3D G3DSA:3.40.50.11900 184 329 3.2E-39 T 31-10-2018 AF_1957 67d96a90bdd0515b5e7b65543ca055b3 329 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 7 327 3.6E-46 T 31-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit AF_1957 67d96a90bdd0515b5e7b65543ca055b3 329 Gene3D G3DSA:3.40.50.11890 2 121 1.1E-31 T 31-10-2018 AF_1200 99fc0e551f460746963668f6d13f5072 278 Pfam PF04199 Putative cyclase 29 180 1.0E-33 T 31-10-2018 IPR007325 Kynurenine formamidase/cyclase-like GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 AF_1200 99fc0e551f460746963668f6d13f5072 278 SUPERFAMILY SSF102198 26 275 4.58E-53 T 31-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 AF_1200 99fc0e551f460746963668f6d13f5072 278 Gene3D G3DSA:3.50.30.50 10 277 9.0E-45 T 31-10-2018 IPR037175 Kynurenine formamidase superfamily GO:0004061|GO:0019441 KEGG: 00380+3.5.1.9|KEGG: 00630+3.5.1.9|MetaCyc: PWY-5651|MetaCyc: PWY-6309|MetaCyc: PWY-7717|MetaCyc: PWY-7733|MetaCyc: PWY-7734|MetaCyc: PWY-7765 AF_1513 a20b9cb131dbd9928898948b9bc66336 194 SUPERFAMILY SSF54001 39 190 1.96E-26 T 31-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AF_1513 a20b9cb131dbd9928898948b9bc66336 194 Gene3D G3DSA:3.90.1720.10 37 169 3.1E-10 T 31-10-2018 AF_1513 a20b9cb131dbd9928898948b9bc66336 194 Pfam PF05708 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family 39 190 2.0E-16 T 31-10-2018 IPR024453 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family AF_1727 2821a20ea8eb0030935848a0dd50e85e 456 SUPERFAMILY SSF53223 33 181 1.44E-54 T 31-10-2018 AF_1727 2821a20ea8eb0030935848a0dd50e85e 456 Pfam PF00390 Malic enzyme, N-terminal domain 39 171 2.1E-28 T 31-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AF_1727 2821a20ea8eb0030935848a0dd50e85e 456 Gene3D G3DSA:3.40.50.10380 18 180 4.1E-71 T 31-10-2018 IPR037062 Malic enzyme, N-terminal domain superfamily GO:0004471|GO:0055114 AF_1727 2821a20ea8eb0030935848a0dd50e85e 456 SUPERFAMILY SSF51735 183 444 2.88E-73 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1727 2821a20ea8eb0030935848a0dd50e85e 456 SMART SM01274 38 171 1.7E-79 T 31-10-2018 IPR012301 Malic enzyme, N-terminal domain GO:0004471|GO:0055114 AF_1727 2821a20ea8eb0030935848a0dd50e85e 456 Pfam PF03949 Malic enzyme, NAD binding domain 184 412 3.4E-25 T 31-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AF_1727 2821a20ea8eb0030935848a0dd50e85e 456 SMART SM00919 183 413 9.3E-113 T 31-10-2018 IPR012302 Malic enzyme, NAD-binding GO:0051287 AF_1727 2821a20ea8eb0030935848a0dd50e85e 456 PIRSF PIRSF000106 49 444 2.2E-81 T 31-10-2018 IPR001891 Malic oxidoreductase GO:0004470|GO:0004471 AF_1727 2821a20ea8eb0030935848a0dd50e85e 456 Gene3D G3DSA:3.40.50.720 181 456 1.5E-94 T 31-10-2018 AF_1108 69363b3fc40254d87958d97f628d3168 168 Hamap MF_00635 Probable deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. 5 163 36.232 T 31-10-2018 IPR023537 Deoxyuridine triphosphate nucleotidohydrolase, archaeal GO:0004170 KEGG: 00240+3.6.1.23|KEGG: 00983+3.6.1.23 AF_1108 69363b3fc40254d87958d97f628d3168 168 Gene3D G3DSA:2.70.40.10 2 168 2.3E-30 T 31-10-2018 IPR036157 dUTPase-like superfamily AF_1108 69363b3fc40254d87958d97f628d3168 168 Pfam PF00692 dUTPase 74 152 1.5E-9 T 31-10-2018 IPR029054 dUTPase-like AF_1108 69363b3fc40254d87958d97f628d3168 168 SUPERFAMILY SSF51283 3 163 5.76E-31 T 31-10-2018 IPR036157 dUTPase-like superfamily AF_2128 1841a4baacc940c2355f39e60dbd2eee 143 Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. 1 138 21.626 T 31-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AF_2128 1841a4baacc940c2355f39e60dbd2eee 143 Gene3D G3DSA:3.40.50.960 1 139 3.5E-32 T 31-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AF_2128 1841a4baacc940c2355f39e60dbd2eee 143 Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase 4 134 4.0E-34 T 31-10-2018 IPR002180 Lumazine/riboflavin synthase GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AF_2128 1841a4baacc940c2355f39e60dbd2eee 143 TIGRFAM TIGR00114 lumazine-synth: 6,7-dimethyl-8-ribityllumazine synthase 4 137 1.9E-52 T 31-10-2018 IPR034964 Lumazine synthase GO:0000906|GO:0009231 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AF_2128 1841a4baacc940c2355f39e60dbd2eee 143 SUPERFAMILY SSF52121 2 138 1.96E-41 T 31-10-2018 IPR036467 Lumazine/riboflavin synthase superfamily GO:0009231|GO:0009349 KEGG: 00740+2.5.1.78|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AF_0188 1d989b046ac3210731c870a169cbae57 77 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 4 28 - T 31-10-2018 IPR001455 TusA-like domain AF_0188 1d989b046ac3210731c870a169cbae57 77 SUPERFAMILY SSF64307 1 71 2.22E-22 T 31-10-2018 IPR036868 TusA-like domain superfamily AF_0188 1d989b046ac3210731c870a169cbae57 77 Gene3D G3DSA:3.30.110.40 1 74 2.4E-23 T 31-10-2018 IPR036868 TusA-like domain superfamily AF_0188 1d989b046ac3210731c870a169cbae57 77 Pfam PF01206 Sulfurtransferase TusA 2 71 2.2E-22 T 31-10-2018 IPR001455 TusA-like domain AF_0628 0aa61edd786d51d83a4ebcca07711aeb 326 SUPERFAMILY SSF53659 2 325 1.13E-126 T 31-10-2018 AF_0628 0aa61edd786d51d83a4ebcca07711aeb 326 ProSitePatterns PS00470 Isocitrate and isopropylmalate dehydrogenases signature. 218 237 - T 31-10-2018 IPR019818 Isocitrate/isopropylmalate dehydrogenase, conserved site GO:0000287|GO:0016616|GO:0051287|GO:0055114 Reactome: R-HSA-71403 AF_0628 0aa61edd786d51d83a4ebcca07711aeb 326 Gene3D G3DSA:3.40.718.10 1 326 1.7E-141 T 31-10-2018 AF_0628 0aa61edd786d51d83a4ebcca07711aeb 326 Pfam PF00180 Isocitrate/isopropylmalate dehydrogenase 3 321 3.1E-107 T 31-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AF_0628 0aa61edd786d51d83a4ebcca07711aeb 326 SMART SM01329 3 321 5.0E-190 T 31-10-2018 IPR024084 Isopropylmalate dehydrogenase-like domain GO:0016616|GO:0055114 Reactome: R-HSA-71403 AF_0628 0aa61edd786d51d83a4ebcca07711aeb 326 TIGRFAM TIGR02088 LEU3_arch: isopropylmalate/isohomocitrate dehydrogenases 4 322 1.9E-156 T 31-10-2018 IPR011828 Isopropylmalate/isohomocitrate dehydrogenase GO:0003862|GO:0009098|GO:0051287|GO:0055114 AF_1522 a60daac7dc3bda37fe9822c51c68bc06 765 SUPERFAMILY SSF55729 454 615 1.47E-9 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase AF_1522 a60daac7dc3bda37fe9822c51c68bc06 765 Pfam PF08351 Domain of unknown function (DUF1726) 80 173 9.5E-29 T 31-10-2018 IPR013562 tRNA(Met) cytidine acetyltransferase TmcA, N-terminal Reactome: R-HSA-6790901 AF_1522 a60daac7dc3bda37fe9822c51c68bc06 765 Pfam PF05127 Helicase 237 420 8.1E-56 T 31-10-2018 IPR007807 Helicase domain Reactome: R-HSA-6790901 AF_1522 a60daac7dc3bda37fe9822c51c68bc06 765 Pfam PF13718 GNAT acetyltransferase 2 460 572 1.9E-29 T 31-10-2018 IPR000182 GNAT domain AF_1522 a60daac7dc3bda37fe9822c51c68bc06 765 Pfam PF13718 GNAT acetyltransferase 2 577 624 2.3E-13 T 31-10-2018 IPR000182 GNAT domain AF_1522 a60daac7dc3bda37fe9822c51c68bc06 765 Gene3D G3DSA:3.40.50.12320 234 410 8.2E-35 T 31-10-2018 AF_1522 a60daac7dc3bda37fe9822c51c68bc06 765 Gene3D G3DSA:3.40.630.30 420 622 1.5E-58 T 31-10-2018 AF_1522 a60daac7dc3bda37fe9822c51c68bc06 765 Hamap MF_01886 tRNA(Met) cytidine acetyltransferase TmcA [tmcA]. 21 762 45.147 T 31-10-2018 IPR024914 tRNA(Met) cytidine acetyltransferase TmcA GO:0000049|GO:0002101|GO:0051391|GO:0051392 AF_1522 a60daac7dc3bda37fe9822c51c68bc06 765 SUPERFAMILY SSF52540 173 358 1.15E-8 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1522 a60daac7dc3bda37fe9822c51c68bc06 765 Gene3D G3DSA:3.40.50.11040 7 221 2.3E-14 T 31-10-2018 AF_2039 ea3d94ae9029181f2dce0de72a441c13 324 Gene3D G3DSA:3.40.50.150 116 324 1.5E-67 T 31-10-2018 AF_2039 ea3d94ae9029181f2dce0de72a441c13 324 Gene3D G3DSA:3.30.70.3130 7 111 4.7E-28 T 31-10-2018 AF_2039 ea3d94ae9029181f2dce0de72a441c13 324 Pfam PF17125 N-terminal domain of 16S rRNA methyltransferase RsmF 26 111 1.4E-9 T 31-10-2018 IPR031341 Ribosomal RNA small subunit methyltransferase F, N-terminal Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 AF_2039 ea3d94ae9029181f2dce0de72a441c13 324 SUPERFAMILY SSF53335 13 316 7.88E-66 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_2039 ea3d94ae9029181f2dce0de72a441c13 324 Pfam PF01189 16S rRNA methyltransferase RsmB/F 116 313 1.0E-60 T 31-10-2018 IPR001678 SAM-dependent methyltransferase RsmB/NOP2-type GO:0008168 AF_2039 ea3d94ae9029181f2dce0de72a441c13 324 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 127 137 3.7E-27 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AF_2039 ea3d94ae9029181f2dce0de72a441c13 324 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 243 259 3.7E-27 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AF_2039 ea3d94ae9029181f2dce0de72a441c13 324 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 193 205 3.7E-27 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AF_2039 ea3d94ae9029181f2dce0de72a441c13 324 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 98 112 3.7E-27 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AF_2039 ea3d94ae9029181f2dce0de72a441c13 324 PRINTS PR02008 RNA (C5-cytosine) methyltransferase signature 298 315 3.7E-27 T 31-10-2018 IPR023267 RNA (C5-cytosine) methyltransferase AF_2039 ea3d94ae9029181f2dce0de72a441c13 324 TIGRFAM TIGR00446 nop2p: NOL1/NOP2/sun family putative RNA methylase 52 315 4.2E-128 T 31-10-2018 IPR011023 Nop2p GO:0003723|GO:0006364|GO:0008757 Reactome: R-HSA-6790901|Reactome: R-HSA-8869496 AF_1308 d039fc5e59ae047d5e769c6d9f1de644 243 Gene3D G3DSA:3.40.50.300 56 240 6.2E-23 T 31-10-2018 AF_1308 d039fc5e59ae047d5e769c6d9f1de644 243 SUPERFAMILY SSF52540 56 236 8.38E-20 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1308 d039fc5e59ae047d5e769c6d9f1de644 243 Pfam PF02223 Thymidylate kinase 61 231 1.4E-36 T 31-10-2018 IPR039430 Thymidylate kinase-like domain KEGG: 00240+2.7.4.9|MetaCyc: PWY-6545|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7197|MetaCyc: PWY-7198|MetaCyc: PWY-7210 AF_1693 2713357cea7afc655715c59aead2371b 329 Hamap MF_00741 Phosphoribosylformylglycinamidine cyclo-ligase [purM]. 4 325 37.197 T 31-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AF_1693 2713357cea7afc655715c59aead2371b 329 SUPERFAMILY SSF56042 163 322 3.84E-43 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AF_1693 2713357cea7afc655715c59aead2371b 329 Pfam PF00586 AIR synthase related protein, N-terminal domain 49 156 2.0E-17 T 31-10-2018 IPR016188 PurM-like, N-terminal domain AF_1693 2713357cea7afc655715c59aead2371b 329 Gene3D G3DSA:3.30.1330.10 4 162 8.4E-47 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AF_1693 2713357cea7afc655715c59aead2371b 329 Pfam PF02769 AIR synthase related protein, C-terminal domain 168 322 3.7E-21 T 31-10-2018 IPR010918 PurM-like, C-terminal domain AF_1693 2713357cea7afc655715c59aead2371b 329 SUPERFAMILY SSF55326 5 162 5.38E-36 T 31-10-2018 IPR036921 PurM-like, N-terminal domain superfamily AF_1693 2713357cea7afc655715c59aead2371b 329 Gene3D G3DSA:3.90.650.10 163 327 3.6E-52 T 31-10-2018 IPR036676 PurM-like, C-terminal domain superfamily AF_1693 2713357cea7afc655715c59aead2371b 329 TIGRFAM TIGR00878 purM: phosphoribosylformylglycinamidine cyclo-ligase 5 315 4.9E-127 T 31-10-2018 IPR004733 Phosphoribosylformylglycinamidine cyclo-ligase GO:0004641|GO:0005737|GO:0006189 KEGG: 00230+6.3.3.1|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277|Reactome: R-HSA-73817 AF_0667 b80998c1bd5dbc22aca6428fd9241fba 61 Pfam PF17253 Family of unknown function (DUF5320) 5 59 2.3E-6 T 31-10-2018 IPR035205 Protein of unknown function DUF5320 AF_1700 a3b1b5b4ba0ab9a630103515735b3fbb 97 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 69 80 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1700 a3b1b5b4ba0ab9a630103515735b3fbb 97 Pfam PF14697 4Fe-4S dicluster domain 30 86 9.4E-11 T 31-10-2018 AF_1700 a3b1b5b4ba0ab9a630103515735b3fbb 97 Gene3D G3DSA:3.30.70.20 8 58 8.7E-6 T 31-10-2018 AF_1700 a3b1b5b4ba0ab9a630103515735b3fbb 97 TIGRFAM TIGR02179 PorD_KorD: 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate family 10 88 3.0E-31 T 31-10-2018 IPR011898 2-oxoacid:acceptor oxidoreductase, delta subunit, pyruvate/2-ketoisovalerate GO:0016625|GO:0051539 AF_1700 a3b1b5b4ba0ab9a630103515735b3fbb 97 SUPERFAMILY SSF54862 21 87 1.68E-22 T 31-10-2018 AF_1700 a3b1b5b4ba0ab9a630103515735b3fbb 97 Gene3D G3DSA:3.30.70.20 59 91 9.2E-9 T 31-10-2018 AF_0389 dfc11202df8252a851089d3bb6e6a2d8 249 Hamap MF_00995 Chorismate dehydratase [mqnA]. 5 248 27.486 T 31-10-2018 IPR030868 Chorismate dehydratase GO:0009234|GO:0016829 KEGG: 00130+4.2.1.151|MetaCyc: PWY-7371|MetaCyc: PWY-7374 AF_0389 dfc11202df8252a851089d3bb6e6a2d8 249 Gene3D G3DSA:3.40.190.10 5 238 1.0E-52 T 31-10-2018 AF_0389 dfc11202df8252a851089d3bb6e6a2d8 249 Gene3D G3DSA:3.40.190.10 72 166 1.0E-52 T 31-10-2018 AF_0389 dfc11202df8252a851089d3bb6e6a2d8 249 SUPERFAMILY SSF53850 3 248 9.31E-61 T 31-10-2018 AF_0389 dfc11202df8252a851089d3bb6e6a2d8 249 Pfam PF02621 Menaquinone biosynthesis 4 243 5.6E-56 T 31-10-2018 IPR003773 Menaquinone biosynthesis enzyme AF_0846 2afee1241008ce208dbeeb8b800246fe 494 TIGRFAM TIGR00831 a_cpa1: Na+/H+ antiporter 7 494 1.9E-212 T 31-10-2018 IPR004705 Cation/H+ exchanger, CPA1 family, bacteria GO:0006812|GO:0015299|GO:0016021 AF_0846 2afee1241008ce208dbeeb8b800246fe 494 Pfam PF00999 Sodium/hydrogen exchanger family 13 376 1.3E-75 T 31-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AF_0846 2afee1241008ce208dbeeb8b800246fe 494 Gene3D G3DSA:1.20.1530.20 2 386 4.4E-15 T 31-10-2018 IPR038770 Sodium/solute symporter superfamily AF_0846 2afee1241008ce208dbeeb8b800246fe 494 PRINTS PR01084 Na+/H+ exchanger signature 119 129 9.6E-6 T 31-10-2018 IPR004709 Na+/H+ exchanger GO:0006814|GO:0006885|GO:0015385|GO:0016021|GO:0055085 Reactome: R-HSA-425986 AF_0846 2afee1241008ce208dbeeb8b800246fe 494 PRINTS PR01084 Na+/H+ exchanger signature 85 93 9.6E-6 T 31-10-2018 IPR004709 Na+/H+ exchanger GO:0006814|GO:0006885|GO:0015385|GO:0016021|GO:0055085 Reactome: R-HSA-425986 AF_0846 2afee1241008ce208dbeeb8b800246fe 494 PRINTS PR01084 Na+/H+ exchanger signature 56 67 9.6E-6 T 31-10-2018 IPR004709 Na+/H+ exchanger GO:0006814|GO:0006885|GO:0015385|GO:0016021|GO:0055085 Reactome: R-HSA-425986 AF_2071 443888348b237649a11286a646891bc3 332 TIGRFAM TIGR01850 argC: N-acetyl-gamma-glutamyl-phosphate reductase 1 332 1.9E-126 T 31-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AF_2071 443888348b237649a11286a646891bc3 332 Pfam PF02774 Semialdehyde dehydrogenase, dimerisation domain 155 303 2.8E-12 T 31-10-2018 IPR012280 Semialdehyde dehydrogenase, dimerisation domain GO:0005737|GO:0008652|GO:0016620|GO:0046983 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AF_2071 443888348b237649a11286a646891bc3 332 Pfam PF01118 Semialdehyde dehydrogenase, NAD binding domain 2 136 6.8E-37 T 31-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AF_2071 443888348b237649a11286a646891bc3 332 ProSitePatterns PS01224 N-acetyl-gamma-glutamyl-phosphate reductase active site. 139 155 - T 31-10-2018 IPR023013 N-acetyl-gamma-glutamyl-phosphate reductase, active site GO:0003942|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AF_2071 443888348b237649a11286a646891bc3 332 Gene3D G3DSA:3.30.360.10 142 300 3.9E-117 T 31-10-2018 AF_2071 443888348b237649a11286a646891bc3 332 Hamap MF_00150 N-acetyl-gamma-glutamyl-phosphate reductase [argC]. 1 326 41.976 T 31-10-2018 IPR000706 N-acetyl-gamma-glutamyl-phosphate reductase, type 1 GO:0003942|GO:0006526|GO:0055114 KEGG: 00220+1.2.1.38|MetaCyc: PWY-5154|MetaCyc: PWY-7400 AF_2071 443888348b237649a11286a646891bc3 332 SUPERFAMILY SSF55347 144 300 3.15E-42 T 31-10-2018 AF_2071 443888348b237649a11286a646891bc3 332 Gene3D G3DSA:3.40.50.720 2 318 3.9E-117 T 31-10-2018 AF_2071 443888348b237649a11286a646891bc3 332 SUPERFAMILY SSF51735 2 167 1.9E-50 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_2071 443888348b237649a11286a646891bc3 332 SMART SM00859 2 136 3.6E-51 T 31-10-2018 IPR000534 Semialdehyde dehydrogenase, NAD-binding GO:0016620|GO:0051287|GO:0055114 AF_0413 63bf9d12b5a25bf8418789ad92de6f5f 277 PIRSF PIRSF029129 1 277 8.7E-108 T 31-10-2018 IPR014846 Protein of unknown function DUF1786, putative pyruvate format-lyase activating enzyme AF_0413 63bf9d12b5a25bf8418789ad92de6f5f 277 Pfam PF08735 Putative pyruvate format-lyase activating enzyme (DUF1786) 1 249 2.0E-77 T 31-10-2018 IPR014846 Protein of unknown function DUF1786, putative pyruvate format-lyase activating enzyme AF_0379 4cd72c337507745072689fd348946cce 524 SUPERFAMILY SSF56821 21 421 1.1E-177 T 31-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 AF_0379 4cd72c337507745072689fd348946cce 524 Pfam PF03598 CO dehydrogenase/acetyl-CoA synthase complex beta subunit 25 178 1.7E-61 T 31-10-2018 IPR004461 CO dehydrogenase/acetyl-CoA synthase complex beta subunit GO:0006084|GO:0018492 KEGG: 00720+2.3.1.169|MetaCyc: PWY-7784 AF_0379 4cd72c337507745072689fd348946cce 524 Gene3D G3DSA:3.30.1650.10 23 201 1.8E-57 T 31-10-2018 IPR038571 Bifunctional carbon monoxide dehydrogenase/acetyl-coa synthase, domain 3 superfamily KEGG: 00720+2.3.1.169|MetaCyc: PWY-7784 AF_0379 4cd72c337507745072689fd348946cce 524 Gene3D G3DSA:3.40.1470.10 305 423 3.5E-45 T 31-10-2018 AF_0379 4cd72c337507745072689fd348946cce 524 Hamap MF_01138 Acetyl-CoA decarbonylase/synthase complex subunit beta [cdhC]. 22 516 60.898 T 31-10-2018 IPR023432 Acetyl-CoA decarbonylase/synthase complex subunit beta, archaeal GO:0006084|GO:0018492 KEGG: 00720+2.3.1.169|MetaCyc: PWY-7784 AF_0379 4cd72c337507745072689fd348946cce 524 Gene3D G3DSA:3.40.970.20 202 290 1.5E-36 T 31-10-2018 AF_0379 4cd72c337507745072689fd348946cce 524 TIGRFAM TIGR00316 cdhC: CO dehydrogenase/CO-methylating acetyl-CoA synthase complex, beta subunit 22 515 4.3E-260 T 31-10-2018 IPR004461 CO dehydrogenase/acetyl-CoA synthase complex beta subunit GO:0006084|GO:0018492 KEGG: 00720+2.3.1.169|MetaCyc: PWY-7784 AF_2280 65d506ffaeef37c98e9f73bb460a2166 100 TIGRFAM TIGR00304 TIGR00304: TIGR00304 family protein 4 95 3.7E-38 T 31-10-2018 IPR002849 Protein of unknown function DUF131 AF_2280 65d506ffaeef37c98e9f73bb460a2166 100 Pfam PF01998 Protein of unknown function DUF131 39 96 9.3E-18 T 31-10-2018 IPR002849 Protein of unknown function DUF131 AF_2370 9d44a9cf0ee14b78936be9c8d644aba6 201 Hamap MF_00343 UPF0148 protein . 82 201 25.432 T 31-10-2018 IPR022954 Uncharacterised protein family UPF0148 AF_2370 9d44a9cf0ee14b78936be9c8d644aba6 201 Pfam PF06677 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) 89 124 8.0E-14 T 31-10-2018 IPR009563 Sjoegren syndrome/scleroderma autoantigen 1 AF_0199 335fdde3f7a617f3ee15d52c94a958fb 410 PIRSF PIRSF016578 4 110 2.3E-6 T 31-10-2018 AF_0199 335fdde3f7a617f3ee15d52c94a958fb 410 PIRSF PIRSF016578 243 409 2.0E-11 T 31-10-2018 AF_0199 335fdde3f7a617f3ee15d52c94a958fb 410 PIRSF PIRSF016578 139 202 0.046 T 31-10-2018 AF_0199 335fdde3f7a617f3ee15d52c94a958fb 410 SUPERFAMILY SSF47203 235 406 8.38E-43 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AF_0199 335fdde3f7a617f3ee15d52c94a958fb 410 Gene3D G3DSA:1.20.140.10 240 404 2.0E-38 T 31-10-2018 AF_0199 335fdde3f7a617f3ee15d52c94a958fb 410 Gene3D G3DSA:2.40.110.10 123 239 1.1E-28 T 31-10-2018 AF_0199 335fdde3f7a617f3ee15d52c94a958fb 410 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 221 1.7E-20 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AF_0199 335fdde3f7a617f3ee15d52c94a958fb 410 SUPERFAMILY SSF56645 2 247 4.32E-65 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AF_0199 335fdde3f7a617f3ee15d52c94a958fb 410 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 360 379 - T 31-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AF_0199 335fdde3f7a617f3ee15d52c94a958fb 410 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 236 402 6.7E-32 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AF_0199 335fdde3f7a617f3ee15d52c94a958fb 410 Gene3D G3DSA:1.10.540.10 1 121 2.6E-34 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AF_0199 335fdde3f7a617f3ee15d52c94a958fb 410 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 120 3.1E-30 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AF_2168 38395be81a05abddeb384dcd635f8828 124 SUPERFAMILY SSF81301 16 90 1.09E-8 T 31-10-2018 AF_0444 2b827451792a6fe0e6a856268d6ab9ed 223 TIGRFAM TIGR01484 HAD-SF-IIB: HAD hydrolase, family IIB 7 189 1.5E-19 T 31-10-2018 IPR006379 HAD-superfamily hydrolase, subfamily IIB Reactome: R-HSA-446205 AF_0444 2b827451792a6fe0e6a856268d6ab9ed 223 Gene3D G3DSA:3.40.50.1000 7 208 3.3E-62 T 31-10-2018 IPR023214 HAD superfamily AF_0444 2b827451792a6fe0e6a856268d6ab9ed 223 TIGRFAM TIGR01482 SPP-subfamily: sucrose-phosphate phosphatase subfamily 7 220 2.3E-83 T 31-10-2018 AF_0444 2b827451792a6fe0e6a856268d6ab9ed 223 TIGRFAM TIGR01487 Pglycolate_arch: phosphoglycolate phosphatase, TA0175-type 5 216 1.2E-89 T 31-10-2018 AF_0444 2b827451792a6fe0e6a856268d6ab9ed 223 Hamap MF_01419 Phosphoglycolate phosphatase. 4 221 32.989 T 31-10-2018 IPR006382 Phosphoglycolate phosphatase GO:0000287|GO:0008967|GO:0016311 KEGG: 00630+3.1.3.18|MetaCyc: PWY-181 AF_0444 2b827451792a6fe0e6a856268d6ab9ed 223 Pfam PF08282 haloacid dehalogenase-like hydrolase 7 96 2.1E-10 T 31-10-2018 AF_0444 2b827451792a6fe0e6a856268d6ab9ed 223 Pfam PF08282 haloacid dehalogenase-like hydrolase 136 216 5.1E-25 T 31-10-2018 AF_0444 2b827451792a6fe0e6a856268d6ab9ed 223 SUPERFAMILY SSF56784 3 217 1.29E-47 T 31-10-2018 IPR036412 HAD-like superfamily AF_0444 2b827451792a6fe0e6a856268d6ab9ed 223 Gene3D G3DSA:3.90.1070.10 81 142 3.3E-62 T 31-10-2018 AF_0780 8ed20aefd44586f8b0c1f400e1bf28cc 312 Gene3D G3DSA:2.40.50.140 63 166 4.5E-28 T 31-10-2018 AF_0780 8ed20aefd44586f8b0c1f400e1bf28cc 312 SUPERFAMILY SSF50249 60 162 9.0E-27 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0780 8ed20aefd44586f8b0c1f400e1bf28cc 312 SUPERFAMILY SSF50249 146 281 1.15E-12 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_2364 fd233bdb7576bfabb6ddba9253dde68a 254 SUPERFAMILY SSF52540 3 235 3.74E-45 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2364 fd233bdb7576bfabb6ddba9253dde68a 254 SMART SM00382 28 220 6.3E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_2364 fd233bdb7576bfabb6ddba9253dde68a 254 Pfam PF00005 ABC transporter 19 163 3.2E-23 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_2364 fd233bdb7576bfabb6ddba9253dde68a 254 Gene3D G3DSA:3.40.50.300 2 240 7.9E-52 T 31-10-2018 AF_1275 dd9bdadc32c2c9b51c2ee31af29f7e32 229 SUPERFAMILY SSF52255 90 223 1.44E-31 T 31-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 AF_1275 dd9bdadc32c2c9b51c2ee31af29f7e32 229 Pfam PF00731 AIR carboxylase 91 224 4.6E-19 T 31-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AF_1275 dd9bdadc32c2c9b51c2ee31af29f7e32 229 Gene3D G3DSA:3.40.50.7700 91 229 4.2E-38 T 31-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 AF_1275 dd9bdadc32c2c9b51c2ee31af29f7e32 229 SMART SM01001 90 224 3.8E-40 T 31-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AF_0476 bf1167086359527a382d9baced57cbf4 79 Gene3D G3DSA:2.10.260.10 7 52 8.5E-10 T 31-10-2018 AF_0476 bf1167086359527a382d9baced57cbf4 79 ProDom PD058861 TRANSCRIPTIONAL ABRB FAMILY REGULATOR AF0476 REGULATOR 3 78 5.0E-36 T 31-10-2018 AF_0476 bf1167086359527a382d9baced57cbf4 79 SMART SM00966 13 64 1.1E-4 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AF_0476 bf1167086359527a382d9baced57cbf4 79 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 16 41 6.6E-6 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AF_0476 bf1167086359527a382d9baced57cbf4 79 SUPERFAMILY SSF89447 11 43 5.62E-9 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily AF_0476 bf1167086359527a382d9baced57cbf4 79 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 14 40 3.6E-9 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AF_0432 e889473dbab43f9fa82c2fd1a5f8e992 366 Gene3D G3DSA:3.40.50.1980 172 364 3.5E-74 T 31-10-2018 AF_0432 e889473dbab43f9fa82c2fd1a5f8e992 366 Pfam PF01497 Periplasmic binding protein 50 296 1.0E-29 T 31-10-2018 IPR002491 ABC transporter periplasmic binding domain AF_0432 e889473dbab43f9fa82c2fd1a5f8e992 366 Gene3D G3DSA:3.40.50.1980 24 171 8.2E-58 T 31-10-2018 AF_0432 e889473dbab43f9fa82c2fd1a5f8e992 366 SUPERFAMILY SSF53807 34 352 1.69E-53 T 31-10-2018 AF_0696 4d9103cfba83dbaeeb67996d3fffeeb8 263 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 212 1.3E-23 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AF_0696 4d9103cfba83dbaeeb67996d3fffeeb8 263 Gene3D G3DSA:3.40.50.300 1 233 4.4E-69 T 31-10-2018 AF_0696 4d9103cfba83dbaeeb67996d3fffeeb8 263 SUPERFAMILY SSF52540 1 234 1.42E-57 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0696 4d9103cfba83dbaeeb67996d3fffeeb8 263 PIRSF PIRSF003092 1 263 2.1E-63 T 31-10-2018 IPR025501 ATP binding protein MinD AF_0696 4d9103cfba83dbaeeb67996d3fffeeb8 263 TIGRFAM TIGR01969 minD_arch: cell division ATPase MinD 3 258 8.3E-121 T 31-10-2018 IPR010224 ATP binding protein MinD, archaea AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 Pfam PF08448 PAS fold 425 517 9.6E-7 T 31-10-2018 IPR013656 PAS fold-4 AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 Gene3D G3DSA:3.30.450.20 105 198 4.4E-5 T 31-10-2018 AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 SMART SM00086 602 642 2.2 T 31-10-2018 IPR001610 PAC motif AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 SMART SM00086 354 396 9.7E-8 T 31-10-2018 IPR001610 PAC motif AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 Pfam PF13188 PAS domain 202 242 0.067 T 31-10-2018 IPR000014 PAS domain AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 Gene3D G3DSA:3.30.450.20 397 515 7.8E-18 T 31-10-2018 AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 Gene3D G3DSA:3.30.450.20 516 640 8.6E-21 T 31-10-2018 AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 SMART SM00091 408 472 2.4E-4 T 31-10-2018 IPR000014 PAS domain AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 SMART SM00091 529 595 2.5E-5 T 31-10-2018 IPR000014 PAS domain AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 SMART SM00091 284 349 4.0E-9 T 31-10-2018 IPR000014 PAS domain AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 SMART SM00091 200 266 140.0 T 31-10-2018 IPR000014 PAS domain AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 SMART SM00091 93 159 16.0 T 31-10-2018 IPR000014 PAS domain AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 SUPERFAMILY SSF55785 514 640 2.44E-20 T 31-10-2018 IPR035965 PAS domain superfamily AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 SMART SM00388 795 856 1.9E-4 T 31-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 SUPERFAMILY SSF55785 290 398 4.03E-27 T 31-10-2018 IPR035965 PAS domain superfamily AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 SUPERFAMILY SSF55781 642 771 6.38E-5 T 31-10-2018 AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 Pfam PF13426 PAS domain 295 395 2.7E-18 T 31-10-2018 IPR000014 PAS domain AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 Pfam PF13426 PAS domain 108 176 0.0023 T 31-10-2018 IPR000014 PAS domain AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 Pfam PF00989 PAS fold 530 630 1.2E-9 T 31-10-2018 IPR013767 PAS fold GO:0006355 AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 Gene3D G3DSA:3.30.450.20 280 396 1.2E-29 T 31-10-2018 AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 281 403 4.5E-33 T 31-10-2018 IPR000014 PAS domain AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 405 524 9.5E-17 T 31-10-2018 IPR000014 PAS domain AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 525 649 7.7E-31 T 31-10-2018 IPR000014 PAS domain AF_0410 9cd4e6ef0687c4a1e87ecc0b37b141a1 863 SUPERFAMILY SSF55785 393 515 1.92E-18 T 31-10-2018 IPR035965 PAS domain superfamily AF_1685 bdfe28805201af6f15bdda0667571feb 248 PIRSF PIRSF005647 1 248 2.5E-85 T 31-10-2018 IPR014433 Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type AF_1685 bdfe28805201af6f15bdda0667571feb 248 SUPERFAMILY SSF52540 1 227 3.89E-39 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1685 bdfe28805201af6f15bdda0667571feb 248 Gene3D G3DSA:3.40.50.300 1 248 3.9E-55 T 31-10-2018 AF_1685 bdfe28805201af6f15bdda0667571feb 248 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 225 4.1E-23 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AF_1995 49e97f761aae9bbd2758ac89685e973b 491 SUPERFAMILY SSF161070 5 482 6.28E-144 T 31-10-2018 IPR037272 Sodium:neurotransmitter symporter superfamily GO:0005328 AF_1995 49e97f761aae9bbd2758ac89685e973b 491 Pfam PF00209 Sodium:neurotransmitter symporter family 5 123 3.1E-36 T 31-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AF_1995 49e97f761aae9bbd2758ac89685e973b 491 Pfam PF00209 Sodium:neurotransmitter symporter family 128 483 5.9E-76 T 31-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AF_1995 49e97f761aae9bbd2758ac89685e973b 491 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 87 113 3.4E-27 T 31-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AF_1995 49e97f761aae9bbd2758ac89685e973b 491 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 431 451 3.4E-27 T 31-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AF_1995 49e97f761aae9bbd2758ac89685e973b 491 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 391 411 3.4E-27 T 31-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AF_1995 49e97f761aae9bbd2758ac89685e973b 491 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 13 34 3.4E-27 T 31-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AF_1995 49e97f761aae9bbd2758ac89685e973b 491 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 42 61 3.4E-27 T 31-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AF_1995 49e97f761aae9bbd2758ac89685e973b 491 PRINTS PR00176 Sodium/chloride neurotransmitter symporter signature 314 333 3.4E-27 T 31-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AF_1995 49e97f761aae9bbd2758ac89685e973b 491 ProSitePatterns PS00610 Sodium:neurotransmitter symporter family signature 1. 29 43 - T 31-10-2018 IPR000175 Sodium:neurotransmitter symporter GO:0005328|GO:0006836|GO:0016021 AF_2007 131d13d61a8811974c5914de4b610f94 219 Gene3D G3DSA:3.40.430.10 1 219 1.1E-70 T 31-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AF_2007 131d13d61a8811974c5914de4b610f94 219 Pfam PF01872 RibD C-terminal domain 3 212 3.1E-66 T 31-10-2018 IPR002734 Bacterial bifunctional deaminase-reductase, C-terminal GO:0008703|GO:0009231|GO:0055114 AF_2007 131d13d61a8811974c5914de4b610f94 219 TIGRFAM TIGR00227 ribD_Cterm: riboflavin-specific deaminase C-terminal domain 1 216 2.5E-82 T 31-10-2018 IPR011549 Riboflavin-specific deaminase, C-terminal GO:0008703|GO:0009231|GO:0050661|GO:0055114 AF_2007 131d13d61a8811974c5914de4b610f94 219 TIGRFAM TIGR01508 rib_reduct_arch: diaminohydroxyphosphoribosylaminopyrimidine reductase 3 216 1.3E-97 T 31-10-2018 IPR006401 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine 1-reductase, archaeal GO:0016491|GO:0055114 KEGG: 00740+1.1.1.302|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AF_2007 131d13d61a8811974c5914de4b610f94 219 SUPERFAMILY SSF53597 1 214 5.37E-55 T 31-10-2018 IPR024072 Dihydrofolate reductase-like domain superfamily Reactome: R-HSA-196757 AF_1934 c90f8edb8011e9ed2ebdf6eb48f4c1f0 283 SUPERFAMILY SSF52402 2 141 1.84E-17 T 31-10-2018 AF_1934 c90f8edb8011e9ed2ebdf6eb48f4c1f0 283 Gene3D G3DSA:3.40.50.620 154 283 1.9E-23 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_1934 c90f8edb8011e9ed2ebdf6eb48f4c1f0 283 Pfam PF00582 Universal stress protein family 57 137 4.1E-16 T 31-10-2018 IPR006016 UspA AF_1934 c90f8edb8011e9ed2ebdf6eb48f4c1f0 283 Pfam PF00582 Universal stress protein family 161 281 2.6E-14 T 31-10-2018 IPR006016 UspA AF_1934 c90f8edb8011e9ed2ebdf6eb48f4c1f0 283 SUPERFAMILY SSF52402 157 281 3.27E-19 T 31-10-2018 AF_1934 c90f8edb8011e9ed2ebdf6eb48f4c1f0 283 PRINTS PR01438 Universal stress protein signature 259 281 1.3E-15 T 31-10-2018 IPR006015 Universal stress protein A AF_1934 c90f8edb8011e9ed2ebdf6eb48f4c1f0 283 PRINTS PR01438 Universal stress protein signature 242 254 1.3E-15 T 31-10-2018 IPR006015 Universal stress protein A AF_1934 c90f8edb8011e9ed2ebdf6eb48f4c1f0 283 PRINTS PR01438 Universal stress protein signature 2 20 1.3E-15 T 31-10-2018 IPR006015 Universal stress protein A AF_1934 c90f8edb8011e9ed2ebdf6eb48f4c1f0 283 Gene3D G3DSA:3.40.50.620 1 147 8.4E-21 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_0478 1815ded5b5c553963e285815ff68f29b 254 SMART SM00849 35 217 4.4E-18 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_0478 1815ded5b5c553963e285815ff68f29b 254 Gene3D G3DSA:3.60.15.10 1 242 4.2E-55 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_0478 1815ded5b5c553963e285815ff68f29b 254 Pfam PF12706 Beta-lactamase superfamily domain 47 217 3.3E-28 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_0478 1815ded5b5c553963e285815ff68f29b 254 SUPERFAMILY SSF56281 1 229 1.04E-48 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_1769 ba4415537af72f3f3e4779005b2f104a 286 Gene3D G3DSA:1.10.3720.10 73 283 8.9E-23 T 31-10-2018 IPR035906 MetI-like superfamily AF_1769 ba4415537af72f3f3e4779005b2f104a 286 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 101 283 6.0E-24 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AF_1769 ba4415537af72f3f3e4779005b2f104a 286 Pfam PF12911 N-terminal TM domain of oligopeptide transport permease C 26 60 3.1E-8 T 31-10-2018 IPR025966 Oligopeptide transport permease C-like, N-terminal domain AF_1769 ba4415537af72f3f3e4779005b2f104a 286 SUPERFAMILY SSF161098 79 267 1.96E-26 T 31-10-2018 IPR035906 MetI-like superfamily AF_2033 92bee12186d553a9538bf238bc045c00 537 Gene3D G3DSA:3.30.300.310 432 537 5.9E-35 T 31-10-2018 AF_2033 92bee12186d553a9538bf238bc045c00 537 Gene3D G3DSA:3.40.50.12780 2 431 2.7E-106 T 31-10-2018 AF_2033 92bee12186d553a9538bf238bc045c00 537 Pfam PF00501 AMP-binding enzyme 24 436 2.6E-88 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_2033 92bee12186d553a9538bf238bc045c00 537 Pfam PF13193 AMP-binding enzyme C-terminal domain 446 525 1.8E-21 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AF_2033 92bee12186d553a9538bf238bc045c00 537 ProSitePatterns PS00455 Putative AMP-binding domain signature. 175 186 - T 31-10-2018 IPR020845 AMP-binding, conserved site AF_2033 92bee12186d553a9538bf238bc045c00 537 SUPERFAMILY SSF56801 10 536 1.23E-129 T 31-10-2018 AF_0421 2bdaea8acd85011306579f67724edc41 171 Pfam PF09824 ArsR transcriptional regulator 8 166 5.8E-64 T 31-10-2018 IPR014517 ArsR transcriptional regulator AF_0421 2bdaea8acd85011306579f67724edc41 171 PIRSF PIRSF022057 1 171 1.0E-84 T 31-10-2018 IPR014517 ArsR transcriptional regulator AF_0421 2bdaea8acd85011306579f67724edc41 171 SUPERFAMILY SSF46785 14 127 2.95E-7 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_2266 fc7835af54b6ea61cef7837b3f429b9d 262 SUPERFAMILY SSF56281 22 221 4.87E-35 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_2266 fc7835af54b6ea61cef7837b3f429b9d 262 Pfam PF00753 Metallo-beta-lactamase superfamily 34 185 2.5E-11 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_2266 fc7835af54b6ea61cef7837b3f429b9d 262 SMART SM00849 15 185 7.9E-26 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_2266 fc7835af54b6ea61cef7837b3f429b9d 262 Gene3D G3DSA:3.60.15.10 14 221 3.0E-35 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_0550 59669a332d344fc9b2fba3adf0aece8c 422 Gene3D G3DSA:2.30.40.10 17 404 8.1E-132 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AF_0550 59669a332d344fc9b2fba3adf0aece8c 422 Pfam PF01979 Amidohydrolase family 48 392 2.4E-76 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AF_0550 59669a332d344fc9b2fba3adf0aece8c 422 SUPERFAMILY SSF51338 1 418 2.8E-27 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AF_0550 59669a332d344fc9b2fba3adf0aece8c 422 Hamap MF_01281 5'-deoxyadenosine deaminase [dadD]. 1 419 44.038 T 31-10-2018 IPR023512 Deaminase MtaD/DadD GO:0019239 AF_0550 59669a332d344fc9b2fba3adf0aece8c 422 Gene3D G3DSA:3.20.20.140 51 338 8.1E-132 T 31-10-2018 AF_0550 59669a332d344fc9b2fba3adf0aece8c 422 SUPERFAMILY SSF51556 50 341 1.6E-90 T 31-10-2018 IPR032466 Metal-dependent hydrolase AF_1996 9b267dbd776cd80d1b851956e295c72c 84 SUPERFAMILY SSF88723 8 77 6.87E-7 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_1996 9b267dbd776cd80d1b851956e295c72c 84 Gene3D G3DSA:3.40.50.1010 7 83 1.4E-6 T 31-10-2018 AF_1799 173ce2dc425aa1372e1046b8b27137b4 249 Gene3D G3DSA:1.20.58.220 26 247 6.7E-52 T 31-10-2018 IPR038078 PhoU-like domain superfamily AF_1799 173ce2dc425aa1372e1046b8b27137b4 249 SUPERFAMILY SSF109755 46 231 4.53E-8 T 31-10-2018 AF_1799 173ce2dc425aa1372e1046b8b27137b4 249 Pfam PF01865 Protein of unknown function DUF47 31 247 8.3E-84 T 31-10-2018 IPR018445 Putative phosphate transport regulator AF_1799 173ce2dc425aa1372e1046b8b27137b4 249 TIGRFAM TIGR00153 TIGR00153: TIGR00153 family protein 26 249 3.1E-93 T 31-10-2018 IPR002727 Protein of unknown function DUF47 AF_2357 21ba7c56ac2e7c936a137b0c6871e3d1 340 Pfam PF01841 Transglutaminase-like superfamily 84 160 6.7E-10 T 31-10-2018 IPR002931 Transglutaminase-like AF_2357 21ba7c56ac2e7c936a137b0c6871e3d1 340 SMART SM00460 108 162 5.5E-16 T 31-10-2018 IPR002931 Transglutaminase-like AF_2357 21ba7c56ac2e7c936a137b0c6871e3d1 340 Gene3D G3DSA:3.10.620.30 38 258 1.5E-19 T 31-10-2018 AF_2357 21ba7c56ac2e7c936a137b0c6871e3d1 340 SUPERFAMILY SSF54001 83 219 8.55E-18 T 31-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AF_1855 7ac7d3f2f97ab12f80fae514bd4d56b9 557 SUPERFAMILY SSF56801 21 551 8.24E-115 T 31-10-2018 AF_1855 7ac7d3f2f97ab12f80fae514bd4d56b9 557 Pfam PF00501 AMP-binding enzyme 28 455 8.0E-76 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_1855 7ac7d3f2f97ab12f80fae514bd4d56b9 557 Gene3D G3DSA:3.40.50.12780 2 450 2.8E-79 T 31-10-2018 AF_1855 7ac7d3f2f97ab12f80fae514bd4d56b9 557 Gene3D G3DSA:3.30.300.310 451 556 4.9E-32 T 31-10-2018 AF_1855 7ac7d3f2f97ab12f80fae514bd4d56b9 557 Pfam PF13193 AMP-binding enzyme C-terminal domain 464 540 7.1E-15 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AF_0727 21c26119c4a81273de008a553537fe44 201 Gene3D G3DSA:3.40.1010.10 1 112 1.9E-19 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AF_0727 21c26119c4a81273de008a553537fe44 201 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 5 180 1.7E-24 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AF_0727 21c26119c4a81273de008a553537fe44 201 PIRSF PIRSF036427 1 201 2.0E-42 T 31-10-2018 IPR012382 Precorrin-2 C(20)-methyltransferase GO:0008757|GO:0009236|GO:0030788 AF_0727 21c26119c4a81273de008a553537fe44 201 SUPERFAMILY SSF53790 3 199 6.15E-28 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AF_0552 fbdaaa8023b38f52ea42478b05fa2b84 88 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 11 88 4.3E-15 T 31-10-2018 IPR010038 MoaD, archaeal-type AF_0552 fbdaaa8023b38f52ea42478b05fa2b84 88 SUPERFAMILY SSF54285 1 88 3.76E-18 T 31-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AF_0552 fbdaaa8023b38f52ea42478b05fa2b84 88 Gene3D G3DSA:3.10.20.30 1 88 3.2E-20 T 31-10-2018 IPR012675 Beta-grasp domain superfamily AF_0552 fbdaaa8023b38f52ea42478b05fa2b84 88 Pfam PF02597 ThiS family 16 88 6.8E-14 T 31-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 AF_2052 64252471609d31b41f2e2c2f3805064c 278 Gene3D G3DSA:3.40.50.970 57 276 4.0E-55 T 31-10-2018 AF_2052 64252471609d31b41f2e2c2f3805064c 278 SUPERFAMILY SSF52518 4 274 4.61E-64 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold AF_2052 64252471609d31b41f2e2c2f3805064c 278 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 33 188 5.6E-20 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AF_0040 1532996b3ea90626639cf7b59077a669 593 Gene3D G3DSA:3.40.50.12610 432 593 8.7E-53 T 31-10-2018 AF_0040 1532996b3ea90626639cf7b59077a669 593 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 31 486 9.7E-23 T 31-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 AF_2361 42c79fcf976b2ea7950fe3eb5fdccf97 291 SUPERFAMILY SSF56281 33 267 1.67E-29 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_2361 42c79fcf976b2ea7950fe3eb5fdccf97 291 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 237 279 7.7E-5 T 31-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain AF_2361 42c79fcf976b2ea7950fe3eb5fdccf97 291 Gene3D G3DSA:3.60.15.10 16 180 7.1E-17 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_2066 e9271020e6802618714f2a25dfb209e5 88 Pfam PF01198 Ribosomal protein L31e 5 74 1.2E-12 T 31-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2066 e9271020e6802618714f2a25dfb209e5 88 ProDom PD006030 RIBOSOMAL 60S L31 RIBONUCLEOPROTEIN L31E 50S L31 SUBUNIT STRAIN PHOSPHORYLATION 5 59 1.0E-24 T 31-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2066 e9271020e6802618714f2a25dfb209e5 88 Hamap MF_00410 50S ribosomal protein L31e [rpl31e]. 3 88 24.196 T 31-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2066 e9271020e6802618714f2a25dfb209e5 88 Gene3D G3DSA:3.10.440.10 1 88 3.8E-31 T 31-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2066 e9271020e6802618714f2a25dfb209e5 88 SUPERFAMILY SSF54575 5 87 2.35E-26 T 31-10-2018 IPR023621 Ribosomal protein L31e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2066 e9271020e6802618714f2a25dfb209e5 88 SMART SM01380 3 84 6.7E-30 T 31-10-2018 IPR000054 Ribosomal protein L31e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2066 e9271020e6802618714f2a25dfb209e5 88 ProSitePatterns PS01144 Ribosomal protein L31e signature. 49 63 - T 31-10-2018 IPR020052 Ribosomal protein L31e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0433 7d146b9def068ba48a357f13809395ae 366 Gene3D G3DSA:2.40.30.70 5 145 1.7E-49 T 31-10-2018 IPR036414 YaeB, N-terminal domain superfamily AF_0433 7d146b9def068ba48a357f13809395ae 366 SUPERFAMILY SSF118196 2 147 5.23E-50 T 31-10-2018 IPR036413 YaeB-like superfamily AF_0433 7d146b9def068ba48a357f13809395ae 366 Gene3D G3DSA:3.30.1330.130 146 312 4.9E-44 T 31-10-2018 AF_0433 7d146b9def068ba48a357f13809395ae 366 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 161 302 9.1E-39 T 31-10-2018 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain AF_0433 7d146b9def068ba48a357f13809395ae 366 TIGRFAM TIGR00104 tRNA_TsaA: tRNA-Thr(GGU) m(6)t(6)A37 methyltransferase TsaA 2 138 4.1E-62 T 31-10-2018 IPR023370 YaeB-like, N-terminal domain AF_0433 7d146b9def068ba48a357f13809395ae 366 ProSitePatterns PS01318 TsaA-like domain signature. 80 91 - T 31-10-2018 IPR023368 Uncharacterised protein family UPF0066, conserved site AF_0433 7d146b9def068ba48a357f13809395ae 366 Pfam PF01980 Uncharacterised protein family UPF0066 21 132 3.7E-37 T 31-10-2018 IPR023370 YaeB-like, N-terminal domain AF_0433 7d146b9def068ba48a357f13809395ae 366 SUPERFAMILY SSF143555 153 318 1.83E-45 T 31-10-2018 AF_0336 d9d068ccb189a6c542a8ae5c513e84aa 370 SUPERFAMILY SSF140914 10 274 1.29E-34 T 31-10-2018 AF_0336 d9d068ccb189a6c542a8ae5c513e84aa 370 Hamap MF_00701 DNA primase large subunit PriL [priL]. 11 369 35.645 T 31-10-2018 IPR023642 DNA primase large subunit PriL GO:0003896 AF_0336 d9d068ccb189a6c542a8ae5c513e84aa 370 Pfam PF04104 Eukaryotic and archaeal DNA primase, large subunit 175 350 2.1E-34 T 31-10-2018 IPR007238 DNA primase large subunit, eukaryotic/archaeal GO:0003896|GO:0006269 Reactome: R-HSA-113501|Reactome: R-HSA-174411|Reactome: R-HSA-174430|Reactome: R-HSA-68952|Reactome: R-HSA-68962|Reactome: R-HSA-69091|Reactome: R-HSA-69166|Reactome: R-HSA-69183 AF_1519 a104bbbfd6e1c7e8a0ef6996d39804c7 195 Pfam PF03358 NADPH-dependent FMN reductase 2 152 9.7E-35 T 31-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AF_1519 a104bbbfd6e1c7e8a0ef6996d39804c7 195 SUPERFAMILY SSF52218 2 192 5.28E-39 T 31-10-2018 IPR029039 Flavoprotein-like superfamily AF_1519 a104bbbfd6e1c7e8a0ef6996d39804c7 195 Gene3D G3DSA:3.40.50.360 2 194 3.1E-37 T 31-10-2018 IPR029039 Flavoprotein-like superfamily AF_1645 afaf5c69924e60f16b730134f292aff2 404 SUPERFAMILY SSF52507 19 218 3.27E-46 T 31-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AF_1645 afaf5c69924e60f16b730134f292aff2 404 Gene3D G3DSA:3.40.50.1950 16 187 3.3E-46 T 31-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AF_1645 afaf5c69924e60f16b730134f292aff2 404 SUPERFAMILY SSF102645 179 399 4.71E-54 T 31-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AF_1645 afaf5c69924e60f16b730134f292aff2 404 Pfam PF02441 Flavoprotein 20 186 2.0E-38 T 31-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AF_1645 afaf5c69924e60f16b730134f292aff2 404 Pfam PF04127 DNA / pantothenate metabolism flavoprotein 194 376 7.0E-50 T 31-10-2018 IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AF_1645 afaf5c69924e60f16b730134f292aff2 404 TIGRFAM TIGR00521 coaBC_dfp: phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 17 399 2.2E-149 T 31-10-2018 IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC GO:0004632|GO:0004633|GO:0010181|GO:0015937|GO:0015941 KEGG: 00770+4.1.1.36+6.3.2.5|MetaCyc: PWY-7851 AF_1645 afaf5c69924e60f16b730134f292aff2 404 Gene3D G3DSA:3.40.50.10300 188 402 6.6E-56 T 31-10-2018 IPR035929 CoaB-like superfamily KEGG: 00770+6.3.2.5|Reactome: R-HSA-196783 AF_2096 383effee0c5039e1d5504108e073d304 221 TIGRFAM TIGR02237 recomb_radB: DNA repair and recombination protein RadB 13 220 7.2E-90 T 31-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 AF_2096 383effee0c5039e1d5504108e073d304 221 PIRSF PIRSF003336 1 221 1.1E-95 T 31-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 AF_2096 383effee0c5039e1d5504108e073d304 221 PRINTS PR01874 DNA repair protein radA signature 15 43 4.4E-7 T 31-10-2018 AF_2096 383effee0c5039e1d5504108e073d304 221 PRINTS PR01874 DNA repair protein radA signature 193 219 4.4E-7 T 31-10-2018 AF_2096 383effee0c5039e1d5504108e073d304 221 Hamap MF_00350 DNA repair and recombination protein RadB [radB]. 12 220 37.781 T 31-10-2018 IPR011939 DNA repair and recombination protein RadB GO:0003684|GO:0005524|GO:0006281|GO:0006310 AF_2096 383effee0c5039e1d5504108e073d304 221 SMART SM00382 23 191 1.4E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_2096 383effee0c5039e1d5504108e073d304 221 Gene3D G3DSA:3.40.50.300 2 221 2.7E-50 T 31-10-2018 AF_2096 383effee0c5039e1d5504108e073d304 221 Pfam PF08423 Rad51 5 220 1.1E-29 T 31-10-2018 IPR013632 DNA recombination and repair protein Rad51-like, C-terminal Reactome: R-HSA-5685942|Reactome: R-HSA-5693554|Reactome: R-HSA-5693568|Reactome: R-HSA-5693579 AF_2096 383effee0c5039e1d5504108e073d304 221 SUPERFAMILY SSF52540 6 220 1.11E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1581 293146609956459009afb3657a68f706 106 SUPERFAMILY SSF51182 15 79 7.8E-8 T 31-10-2018 IPR011051 RmlC-like cupin domain superfamily AF_1581 293146609956459009afb3657a68f706 106 Gene3D G3DSA:2.60.120.10 3 66 1.6E-7 T 31-10-2018 IPR014710 RmlC-like jelly roll fold AF_1452 bdee2eec6fbddfd1617ac1854ca4226e 438 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 341 436 1.2E-19 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_1452 bdee2eec6fbddfd1617ac1854ca4226e 438 SMART SM00091 3 69 2.1E-8 T 31-10-2018 IPR000014 PAS domain AF_1452 bdee2eec6fbddfd1617ac1854ca4226e 438 SMART SM00091 126 191 8.4E-11 T 31-10-2018 IPR000014 PAS domain AF_1452 bdee2eec6fbddfd1617ac1854ca4226e 438 SUPERFAMILY SSF55785 111 236 8.54E-26 T 31-10-2018 IPR035965 PAS domain superfamily AF_1452 bdee2eec6fbddfd1617ac1854ca4226e 438 SMART SM00086 198 238 110.0 T 31-10-2018 IPR001610 PAC motif AF_1452 bdee2eec6fbddfd1617ac1854ca4226e 438 SMART SM00086 74 114 0.24 T 31-10-2018 IPR001610 PAC motif AF_1452 bdee2eec6fbddfd1617ac1854ca4226e 438 SUPERFAMILY SSF55874 310 437 6.16E-28 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_1452 bdee2eec6fbddfd1617ac1854ca4226e 438 Gene3D G3DSA:3.30.450.20 2 112 2.4E-21 T 31-10-2018 AF_1452 bdee2eec6fbddfd1617ac1854ca4226e 438 Gene3D G3DSA:3.30.450.20 113 236 5.6E-25 T 31-10-2018 AF_1452 bdee2eec6fbddfd1617ac1854ca4226e 438 Pfam PF08447 PAS fold 148 226 7.9E-12 T 31-10-2018 IPR013655 PAS fold-3 GO:0005515 AF_1452 bdee2eec6fbddfd1617ac1854ca4226e 438 Pfam PF08447 PAS fold 27 103 3.8E-10 T 31-10-2018 IPR013655 PAS fold-3 GO:0005515 AF_1452 bdee2eec6fbddfd1617ac1854ca4226e 438 SMART SM00387 337 438 3.0E-24 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_1452 bdee2eec6fbddfd1617ac1854ca4226e 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 423 436 1.5E-8 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1452 bdee2eec6fbddfd1617ac1854ca4226e 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 399 417 1.5E-8 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1452 bdee2eec6fbddfd1617ac1854ca4226e 438 PRINTS PR00344 Bacterial sensor protein C-terminal signature 372 386 1.5E-8 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1452 bdee2eec6fbddfd1617ac1854ca4226e 438 SUPERFAMILY SSF55785 15 123 2.74E-24 T 31-10-2018 IPR035965 PAS domain superfamily AF_1452 bdee2eec6fbddfd1617ac1854ca4226e 438 Gene3D G3DSA:3.30.565.10 300 438 2.6E-29 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_1452 bdee2eec6fbddfd1617ac1854ca4226e 438 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 122 245 4.8E-32 T 31-10-2018 IPR000014 PAS domain AF_1452 bdee2eec6fbddfd1617ac1854ca4226e 438 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 5 121 2.5E-20 T 31-10-2018 IPR000014 PAS domain AF_0244 be5ab75a73696119d4779ed037bfbd2b 409 SMART SM01074 301 382 4.5E-34 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 AF_0244 be5ab75a73696119d4779ed037bfbd2b 409 SUPERFAMILY SSF52540 13 280 2.09E-56 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0244 be5ab75a73696119d4779ed037bfbd2b 409 Gene3D G3DSA:1.10.8.60 13 284 2.6E-106 T 31-10-2018 AF_0244 be5ab75a73696119d4779ed037bfbd2b 409 Pfam PF13401 AAA domain 52 161 5.5E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0244 be5ab75a73696119d4779ed037bfbd2b 409 Pfam PF09079 CDC6, C terminal winged helix domain 305 380 3.3E-24 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 AF_0244 be5ab75a73696119d4779ed037bfbd2b 409 Gene3D G3DSA:1.10.10.10 293 392 4.3E-32 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0244 be5ab75a73696119d4779ed037bfbd2b 409 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 13 371 1.8E-146 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea AF_0244 be5ab75a73696119d4779ed037bfbd2b 409 Gene3D G3DSA:3.40.50.300 29 205 2.6E-106 T 31-10-2018 AF_0244 be5ab75a73696119d4779ed037bfbd2b 409 SUPERFAMILY SSF46785 286 391 3.26E-29 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0244 be5ab75a73696119d4779ed037bfbd2b 409 SMART SM00382 51 207 2.1E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0244 be5ab75a73696119d4779ed037bfbd2b 409 Hamap MF_01407 ORC1-type DNA replication protein. 6 382 32.446 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea AF_2427 f709c436fe9a046447a54d6661f625e4 627 Pfam PF04312 Protein of unknown function (DUF460) 210 342 2.1E-50 T 31-10-2018 IPR007408 Protein of unknown function DUF460 AF_0065 86a909438869e481b231d8a15e32ebda 137 SUPERFAMILY SSF88723 1 130 7.85E-24 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_0065 86a909438869e481b231d8a15e32ebda 137 Gene3D G3DSA:3.40.50.1010 2 132 2.8E-17 T 31-10-2018 AF_0065 86a909438869e481b231d8a15e32ebda 137 Pfam PF01850 PIN domain 3 126 2.2E-22 T 31-10-2018 IPR002716 PIN domain AF_0065 86a909438869e481b231d8a15e32ebda 137 SMART SM00670 1 123 7.9E-20 T 31-10-2018 IPR002716 PIN domain AF_1786 ecee219304e8c9c7dd02ae802b181943 177 SUPERFAMILY SSF50475 12 169 1.96E-39 T 31-10-2018 AF_1786 ecee219304e8c9c7dd02ae802b181943 177 Gene3D G3DSA:2.30.110.10 4 173 7.6E-46 T 31-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AF_1786 ecee219304e8c9c7dd02ae802b181943 177 Pfam PF01613 Flavin reductase like domain 18 151 3.1E-25 T 31-10-2018 IPR002563 Flavin reductase like domain GO:0010181 AF_1786 ecee219304e8c9c7dd02ae802b181943 177 SMART SM00903 12 161 4.0E-22 T 31-10-2018 IPR002563 Flavin reductase like domain GO:0010181 AF_0505 7ec09064835300dd961ec168659d3bbb 208 SUPERFAMILY SSF89550 2 182 6.67E-42 T 31-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AF_0505 7ec09064835300dd961ec168659d3bbb 208 Pfam PF02811 PHP domain 5 74 1.9E-11 T 31-10-2018 IPR004013 PHP domain GO:0003824 AF_0505 7ec09064835300dd961ec168659d3bbb 208 SMART SM00481 4 71 1.3E-22 T 31-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal AF_0505 7ec09064835300dd961ec168659d3bbb 208 Gene3D G3DSA:3.20.20.140 1 198 4.8E-44 T 31-10-2018 AF_0505 7ec09064835300dd961ec168659d3bbb 208 Pfam PF13263 PHP-associated 136 181 7.7E-11 T 31-10-2018 AF_1745 aa7442094cb3b0012c682abf72900a16 175 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 43 5.1E-11 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 AF_1530 501a1f02cf0682d4a8f3479280f2814e 119 PIRSF PIRSF005053 2 119 4.3E-32 T 31-10-2018 IPR010924 DNA-directed RNA polymerase subunit F (Rpo4) AF_1530 501a1f02cf0682d4a8f3479280f2814e 119 Gene3D G3DSA:1.10.287.420 4 53 2.0E-7 T 31-10-2018 AF_1530 501a1f02cf0682d4a8f3479280f2814e 119 SUPERFAMILY SSF47819 4 114 1.31E-24 T 31-10-2018 IPR010997 HRDC-like superfamily GO:0000166|GO:0003824|GO:0044237 AF_1530 501a1f02cf0682d4a8f3479280f2814e 119 Gene3D G3DSA:1.10.150.80 54 119 1.7E-23 T 31-10-2018 AF_1530 501a1f02cf0682d4a8f3479280f2814e 119 Pfam PF03874 RNA polymerase Rpb4 18 118 2.0E-7 T 31-10-2018 IPR005574 RNA polymerase subunit RPB4/RPC9 GO:0006352|GO:0030880 AF_1777 c99c6a015069ccc3b2f6fce7d96bc927 245 Pfam PF01784 NIF3 (NGG1p interacting factor 3) 5 232 2.0E-55 T 31-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 AF_1777 c99c6a015069ccc3b2f6fce7d96bc927 245 TIGRFAM TIGR00486 YbgI_SA1388: dinuclear metal center protein, YbgI/SA1388 family 1 244 6.3E-79 T 31-10-2018 IPR002678 GTP cyclohydrolase 1 type 2/Nif3 AF_1777 c99c6a015069ccc3b2f6fce7d96bc927 245 SUPERFAMILY SSF102705 1 241 2.49E-64 T 31-10-2018 IPR036069 GTP cyclohydrolase 1 type 2/Nif3 superfamily AF_1777 c99c6a015069ccc3b2f6fce7d96bc927 245 Gene3D G3DSA:3.40.1390.30 96 216 4.7E-74 T 31-10-2018 AF_1777 c99c6a015069ccc3b2f6fce7d96bc927 245 Gene3D G3DSA:3.40.1390.30 14 230 4.7E-74 T 31-10-2018 AF_0875 6f5c1d46f6803d1517b3ecff8d967080 77 Pfam PF01423 LSM domain 8 72 3.1E-22 T 31-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type AF_0875 6f5c1d46f6803d1517b3ecff8d967080 77 Gene3D G3DSA:2.30.30.100 2 77 3.3E-26 T 31-10-2018 AF_0875 6f5c1d46f6803d1517b3ecff8d967080 77 SMART SM00651 7 72 1.8E-25 T 31-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type AF_0875 6f5c1d46f6803d1517b3ecff8d967080 77 Hamap MF_00257 Putative snRNP Sm-like protein. 1 72 25.424 T 31-10-2018 IPR022901 snRNP Sm-like, putative, archaea AF_0875 6f5c1d46f6803d1517b3ecff8d967080 77 SUPERFAMILY SSF50182 3 74 2.77E-20 T 31-10-2018 IPR010920 LSM domain superfamily AF_1039 fb1cfa2ae8cf2df9d89331c94e622834 205 SUPERFAMILY SSF103039 10 202 9.02E-45 T 31-10-2018 IPR028976 CheC-like superfamily AF_1039 fb1cfa2ae8cf2df9d89331c94e622834 205 Pfam PF04509 CheC-like family 109 144 6.2E-12 T 31-10-2018 IPR007597 CheC-like protein GO:0016787 AF_1039 fb1cfa2ae8cf2df9d89331c94e622834 205 Pfam PF04509 CheC-like family 13 49 8.1E-15 T 31-10-2018 IPR007597 CheC-like protein GO:0016787 AF_1039 fb1cfa2ae8cf2df9d89331c94e622834 205 Gene3D G3DSA:3.40.1550.10 9 201 2.1E-48 T 31-10-2018 IPR028976 CheC-like superfamily AF_2281 67c73cfaff6c9ecd14d5b119e375361b 613 Pfam PF02730 Aldehyde ferredoxin oxidoreductase, N-terminal domain 7 216 4.5E-79 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 AF_2281 67c73cfaff6c9ecd14d5b119e375361b 613 Gene3D G3DSA:1.10.569.10 253 441 4.2E-144 T 31-10-2018 IPR013984 Aldehyde ferredoxin oxidoreductase, domain 2 AF_2281 67c73cfaff6c9ecd14d5b119e375361b 613 Pfam PF01314 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 232 612 1.2E-146 T 31-10-2018 IPR001203 Aldehyde ferredoxin oxidoreductase, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 AF_2281 67c73cfaff6c9ecd14d5b119e375361b 613 SUPERFAMILY SSF56228 3 221 5.62E-69 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily AF_2281 67c73cfaff6c9ecd14d5b119e375361b 613 SMART SM00790 5 218 9.4E-123 T 31-10-2018 IPR013983 Aldehyde ferredoxin oxidoreductase, N-terminal GO:0016491|GO:0016625|GO:0051536|GO:0055114 AF_2281 67c73cfaff6c9ecd14d5b119e375361b 613 Gene3D G3DSA:3.60.9.10 2 222 1.1E-81 T 31-10-2018 IPR036503 Aldehyde ferredoxin oxidoreductase, N-terminal domain superfamily AF_2281 67c73cfaff6c9ecd14d5b119e375361b 613 SUPERFAMILY SSF48310 222 612 5.49E-145 T 31-10-2018 IPR036021 Aldehyde ferredoxin oxidoreductase-like, C-terminal GO:0009055|GO:0016491|GO:0016625|GO:0051536|GO:0055114 AF_2281 67c73cfaff6c9ecd14d5b119e375361b 613 Gene3D G3DSA:1.10.599.10 251 612 4.2E-144 T 31-10-2018 IPR013985 Aldehyde ferredoxin oxidoreductase, domain 3 GO:0016625|GO:0051536|GO:0055114 KEGG: 00030+1.2.7.5 AF_1289 fece652f18a3cec7d5ff6b4ab3a3312e 346 Pfam PF03308 ArgK protein 18 312 5.3E-125 T 31-10-2018 AF_1289 fece652f18a3cec7d5ff6b4ab3a3312e 346 SUPERFAMILY SSF52540 3 335 9.18E-74 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1289 fece652f18a3cec7d5ff6b4ab3a3312e 346 TIGRFAM TIGR00750 lao: LAO/AO transport system ATPase 13 337 2.3E-146 T 31-10-2018 IPR005129 SIMIBI class G3E GTPase, ArgK/MeaB GO:0003924|GO:0005525 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AF_1289 fece652f18a3cec7d5ff6b4ab3a3312e 346 Gene3D G3DSA:3.40.50.300 44 280 1.2E-80 T 31-10-2018 AF_1289 fece652f18a3cec7d5ff6b4ab3a3312e 346 Gene3D G3DSA:1.20.5.170 3 42 1.4E-6 T 31-10-2018 AF_1653 f98a068f915f4ed13bd34b752be55e83 270 Pfam PF00082 Subtilase family 126 232 1.5E-21 T 31-10-2018 IPR000209 Peptidase S8/S53 domain GO:0004252|GO:0006508 AF_1653 f98a068f915f4ed13bd34b752be55e83 270 PRINTS PR00723 Subtilisin serine protease family (S8) signature 163 176 3.1E-9 T 31-10-2018 IPR015500 Peptidase S8, subtilisin-related AF_1653 f98a068f915f4ed13bd34b752be55e83 270 PRINTS PR00723 Subtilisin serine protease family (S8) signature 126 145 3.1E-9 T 31-10-2018 IPR015500 Peptidase S8, subtilisin-related AF_1653 f98a068f915f4ed13bd34b752be55e83 270 ProSitePatterns PS00137 Serine proteases, subtilase family, histidine active site. 167 177 - T 31-10-2018 IPR022398 Peptidase S8, subtilisin, His-active site AF_1653 f98a068f915f4ed13bd34b752be55e83 270 SUPERFAMILY SSF52743 109 225 7.46E-46 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AF_1653 f98a068f915f4ed13bd34b752be55e83 270 ProSitePatterns PS00136 Serine proteases, subtilase family, aspartic acid active site. 131 141 - T 31-10-2018 IPR023827 Peptidase S8, subtilisin, Asp-active site AF_1653 f98a068f915f4ed13bd34b752be55e83 270 Gene3D G3DSA:3.40.50.200 81 254 3.8E-46 T 31-10-2018 IPR036852 Peptidase S8/S53 domain superfamily GO:0004252|GO:0006508 AF_1361 e20f3683bda27bf7d16b2a170c313c72 135 Pfam PF01451 Low molecular weight phosphotyrosine protein phosphatase 3 123 1.6E-23 T 31-10-2018 IPR023485 Phosphotyrosine protein phosphatase I AF_1361 e20f3683bda27bf7d16b2a170c313c72 135 SMART SM00226 1 125 4.6E-53 T 31-10-2018 IPR023485 Phosphotyrosine protein phosphatase I AF_1361 e20f3683bda27bf7d16b2a170c313c72 135 Gene3D G3DSA:3.40.50.2300 2 125 3.7E-47 T 31-10-2018 AF_1361 e20f3683bda27bf7d16b2a170c313c72 135 SUPERFAMILY SSF52788 2 123 7.85E-33 T 31-10-2018 IPR036196 Phosphotyrosine protein phosphatase I superfamily AF_2108 162cb7bb6d0fce6dc6026f7726d6f2ca 280 Pfam PF02593 Domain of unknown function 9 264 8.7E-80 T 31-10-2018 IPR003745 Protein of unknown function DUF166 AF_2179 dcbb4ac6c9f73364a47c8ea26339de83 239 Pfam PF02391 MoaE protein 117 215 3.4E-24 T 31-10-2018 IPR003448 Molybdopterin biosynthesis MoaE GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 AF_2179 dcbb4ac6c9f73364a47c8ea26339de83 239 Gene3D G3DSA:3.90.1170.40 103 239 3.9E-36 T 31-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 AF_2179 dcbb4ac6c9f73364a47c8ea26339de83 239 SUPERFAMILY SSF54690 120 235 1.07E-36 T 31-10-2018 IPR036563 Molybdopterin biosynthesis MoaE subunit superfamily GO:0006777 KEGG: 00790+2.8.1.12|MetaCyc: PWY-6823|MetaCyc: PWY-7887|Reactome: R-HSA-947581 AF_1623 a2041a6d4bd707b2d423ed35f33b1146 390 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 235 248 - T 31-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AF_1623 a2041a6d4bd707b2d423ed35f33b1146 390 SUPERFAMILY SSF53383 13 386 1.63E-113 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AF_1623 a2041a6d4bd707b2d423ed35f33b1146 390 Gene3D G3DSA:3.40.640.10 30 390 7.0E-121 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AF_1623 a2041a6d4bd707b2d423ed35f33b1146 390 Pfam PF00155 Aminotransferase class I and II 37 380 4.0E-62 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AF_2304 362bae59f58d968b7632c33ba167ce83 112 Gene3D G3DSA:3.30.460.10 2 104 6.1E-14 T 31-10-2018 AF_2304 362bae59f58d968b7632c33ba167ce83 112 Pfam PF01909 Nucleotidyltransferase domain 12 68 2.4E-10 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AF_2304 362bae59f58d968b7632c33ba167ce83 112 SUPERFAMILY SSF81301 3 92 2.16E-14 T 31-10-2018 AF_2146 2ce7b167eb24f15c822974e39b1befb1 355 Pfam PF16897 C-terminal region of MMR_HSR1 domain 184 280 5.7E-31 T 31-10-2018 IPR031662 GTP binding protein, second domain AF_2146 2ce7b167eb24f15c822974e39b1befb1 355 Pfam PF02824 TGS domain 282 354 2.0E-24 T 31-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 AF_2146 2ce7b167eb24f15c822974e39b1befb1 355 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 66 86 5.3E-31 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 AF_2146 2ce7b167eb24f15c822974e39b1befb1 355 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 87 105 5.3E-31 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 AF_2146 2ce7b167eb24f15c822974e39b1befb1 355 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 131 149 5.3E-31 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 AF_2146 2ce7b167eb24f15c822974e39b1befb1 355 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 114 129 5.3E-31 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 AF_2146 2ce7b167eb24f15c822974e39b1befb1 355 SUPERFAMILY SSF52540 66 295 1.92E-54 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2146 2ce7b167eb24f15c822974e39b1befb1 355 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 66 178 2.8E-18 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AF_2146 2ce7b167eb24f15c822974e39b1befb1 355 Pfam PF01926 50S ribosome-binding GTPase 66 174 9.4E-23 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 AF_2146 2ce7b167eb24f15c822974e39b1befb1 355 Gene3D G3DSA:3.10.20.30 280 355 2.5E-33 T 31-10-2018 IPR012675 Beta-grasp domain superfamily AF_2146 2ce7b167eb24f15c822974e39b1befb1 355 ProSitePatterns PS00905 GTP1/OBG family signature. 116 129 - T 31-10-2018 IPR006074 GTP1/OBG, conserved site GO:0005525 AF_2146 2ce7b167eb24f15c822974e39b1befb1 355 SUPERFAMILY SSF81271 276 354 2.75E-19 T 31-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AF_1829 5daa263983b4796a37ba7a792dfc9b46 353 Gene3D G3DSA:3.40.50.12280 13 167 5.4E-50 T 31-10-2018 AF_1829 5daa263983b4796a37ba7a792dfc9b46 353 Pfam PF00329 Respiratory-chain NADH dehydrogenase, 30 Kd subunit 227 349 3.0E-27 T 31-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1829 5daa263983b4796a37ba7a792dfc9b46 353 SUPERFAMILY SSF143243 206 352 1.07E-34 T 31-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1829 5daa263983b4796a37ba7a792dfc9b46 353 Gene3D G3DSA:3.30.460.80 178 327 7.1E-23 T 31-10-2018 IPR037232 NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1829 5daa263983b4796a37ba7a792dfc9b46 353 ProDom PD001581 OXIDOREDUCTASE SUBUNIT NADH DEHYDROGENASE CHAIN C NAD DEHYDROGENASE UBIQUINONE F420H2 279 323 3.0E-19 T 31-10-2018 IPR001268 NADH:ubiquinone oxidoreductase, 30kDa subunit GO:0008137|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1829 5daa263983b4796a37ba7a792dfc9b46 353 Pfam PF01058 NADH ubiquinone oxidoreductase, 20 Kd subunit 65 144 1.3E-20 T 31-10-2018 IPR006137 NADH:ubiquinone oxidoreductase-like, 20kDa subunit GO:0051536|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1829 5daa263983b4796a37ba7a792dfc9b46 353 TIGRFAM TIGR01957 nuoB_fam: NADH-quinone oxidoreductase, B subunit 19 150 1.8E-43 T 31-10-2018 IPR006138 NADH-ubiquinone oxidoreductase, 20 Kd subunit GO:0008137|GO:0048038|GO:0051539|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1829 5daa263983b4796a37ba7a792dfc9b46 353 SUPERFAMILY SSF56770 18 154 6.67E-50 T 31-10-2018 AF_1899 0e987268fb581402ee2ed2f88f1451ef 399 Hamap MF_00007 DNA primase DnaG [dnaG]. 18 397 36.537 T 31-10-2018 IPR020607 DNA primase DnaG, archaea GO:0000178|GO:0003896|GO:0008143 AF_1899 0e987268fb581402ee2ed2f88f1451ef 399 Pfam PF13662 Toprim domain 182 266 3.9E-13 T 31-10-2018 IPR006171 TOPRIM domain AF_1899 0e987268fb581402ee2ed2f88f1451ef 399 SMART SM00493 182 251 2.4E-12 T 31-10-2018 IPR006171 TOPRIM domain AF_1899 0e987268fb581402ee2ed2f88f1451ef 399 Gene3D G3DSA:3.40.1360.10 175 282 1.4E-14 T 31-10-2018 AF_1899 0e987268fb581402ee2ed2f88f1451ef 399 SUPERFAMILY SSF56731 175 275 2.14E-11 T 31-10-2018 AF_0578 c43db234b5b842164d2afbb825284754 384 SUPERFAMILY SSF53187 6 381 1.31E-34 T 31-10-2018 AF_0578 c43db234b5b842164d2afbb825284754 384 Pfam PF04389 Peptidase family M28 207 377 3.9E-17 T 31-10-2018 IPR007484 Peptidase M28 AF_2116 9682e3eb9e57758dfe56f13781945127 492 ProSitePatterns PS01234 Glutamyl-tRNA(Gln) amidotransferase subunit B signature. 168 182 - T 31-10-2018 IPR017958 Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site GO:0016884 AF_2116 9682e3eb9e57758dfe56f13781945127 492 Hamap MF_00121 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B [gatB]. 22 492 36.831 T 31-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 AF_2116 9682e3eb9e57758dfe56f13781945127 492 Pfam PF02637 GatB domain 344 491 1.9E-47 T 31-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 AF_2116 9682e3eb9e57758dfe56f13781945127 492 Gene3D G3DSA:1.10.150.380 313 430 1.0E-26 T 31-10-2018 AF_2116 9682e3eb9e57758dfe56f13781945127 492 SUPERFAMILY SSF89095 313 418 3.79E-22 T 31-10-2018 IPR003789 Aspartyl/glutamyl-tRNA amidotransferase subunit B-like GO:0016884 AF_2116 9682e3eb9e57758dfe56f13781945127 492 SUPERFAMILY SSF55931 25 312 1.83E-106 T 31-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AF_2116 9682e3eb9e57758dfe56f13781945127 492 Gene3D G3DSA:1.10.10.410 434 492 3.1E-22 T 31-10-2018 IPR023168 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, C-terminal AF_2116 9682e3eb9e57758dfe56f13781945127 492 SMART SM00845 344 491 9.9E-53 T 31-10-2018 IPR018027 Asn/Gln amidotransferase GO:0016884 AF_2116 9682e3eb9e57758dfe56f13781945127 492 Pfam PF02934 GatB/GatE catalytic domain 25 301 1.8E-103 T 31-10-2018 IPR006075 Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic GO:0016874 AF_2116 9682e3eb9e57758dfe56f13781945127 492 TIGRFAM TIGR00133 gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit 21 492 5.5E-205 T 31-10-2018 IPR004413 Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit GO:0016884 AF_1419 29f0ed0df1baa9191e2e731a5d8c6a9a 271 Gene3D G3DSA:3.40.50.2020 12 130 8.1E-73 T 31-10-2018 AF_1419 29f0ed0df1baa9191e2e731a5d8c6a9a 271 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 1 104 8.1E-16 T 31-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AF_1419 29f0ed0df1baa9191e2e731a5d8c6a9a 271 SUPERFAMILY SSF53271 73 255 4.14E-34 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like AF_1419 29f0ed0df1baa9191e2e731a5d8c6a9a 271 Hamap MF_00583_A Putative ribose-phosphate pyrophosphokinase [prs]. 2 269 36.437 T 31-10-2018 IPR037514 Ribose-phosphate pyrophosphokinase, archaea GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AF_1419 29f0ed0df1baa9191e2e731a5d8c6a9a 271 SMART SM01400 1 106 3.8E-32 T 31-10-2018 AF_1419 29f0ed0df1baa9191e2e731a5d8c6a9a 271 Pfam PF00156 Phosphoribosyl transferase domain 139 231 7.5E-17 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AF_1419 29f0ed0df1baa9191e2e731a5d8c6a9a 271 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 1 271 3.3E-90 T 31-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AF_1419 29f0ed0df1baa9191e2e731a5d8c6a9a 271 Gene3D G3DSA:3.40.50.2020 131 254 8.1E-73 T 31-10-2018 AF_1831 f17b1d43762a24ed970abedd0e667bd1 369 Hamap MF_01350 NAD(P)H-quinone oxidoreductase subunit 1, chloroplastic [ndhA]. 45 368 18.255 T 31-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1831 f17b1d43762a24ed970abedd0e667bd1 369 Pfam PF00146 NADH dehydrogenase 61 360 3.9E-81 T 31-10-2018 IPR001694 NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H GO:0016020|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_2078 f0f84342cbe7ce4ff670b8cfe9885fb8 343 Gene3D G3DSA:2.10.109.10 37 118 1.0E-5 T 31-10-2018 AF_2078 f0f84342cbe7ce4ff670b8cfe9885fb8 343 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 10 115 2.3E-17 T 31-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 AF_2078 f0f84342cbe7ce4ff670b8cfe9885fb8 343 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 86 97 2.7E-7 T 31-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 AF_2078 f0f84342cbe7ce4ff670b8cfe9885fb8 343 PRINTS PR00728 Eukaryotic signal peptidase (S26B) family signature 36 51 2.7E-7 T 31-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 AF_2078 f0f84342cbe7ce4ff670b8cfe9885fb8 343 ProSitePatterns PS00501 Signal peptidases I serine active site. 38 45 - T 31-10-2018 IPR019756 Peptidase S26A, signal peptidase I, serine active site GO:0008236|GO:0016021 Reactome: R-HSA-1799339|Reactome: R-HSA-381771|Reactome: R-HSA-400511|Reactome: R-HSA-422085 AF_2078 f0f84342cbe7ce4ff670b8cfe9885fb8 343 Pfam PF00717 Peptidase S24-like 35 91 1.5E-13 T 31-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AF_2078 f0f84342cbe7ce4ff670b8cfe9885fb8 343 SUPERFAMILY SSF51306 35 141 2.62E-12 T 31-10-2018 IPR036286 LexA/Signal peptidase-like superfamily AF_1170 5463f25df194d9eb5cc40e6bf4ba0ca6 370 SMART SM00382 31 203 0.39 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1170 5463f25df194d9eb5cc40e6bf4ba0ca6 370 SMART SM00382 231 370 3.2E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1170 5463f25df194d9eb5cc40e6bf4ba0ca6 370 Pfam PF00005 ABC transporter 228 330 2.1E-10 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_1170 5463f25df194d9eb5cc40e6bf4ba0ca6 370 SUPERFAMILY SSF52540 228 369 2.37E-26 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1170 5463f25df194d9eb5cc40e6bf4ba0ca6 370 Gene3D G3DSA:3.40.50.300 222 370 1.9E-27 T 31-10-2018 AF_1170 5463f25df194d9eb5cc40e6bf4ba0ca6 370 Gene3D G3DSA:3.40.50.300 7 221 6.2E-31 T 31-10-2018 AF_1170 5463f25df194d9eb5cc40e6bf4ba0ca6 370 SUPERFAMILY SSF52540 25 204 9.12E-30 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1170 5463f25df194d9eb5cc40e6bf4ba0ca6 370 Pfam PF00005 ABC transporter 37 166 1.4E-16 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0093 b2f8d86b2b6613b6eca5b8a4368e6d04 261 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 69 247 2.1E-15 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AF_0093 b2f8d86b2b6613b6eca5b8a4368e6d04 261 Gene3D G3DSA:1.10.3720.10 1 261 3.3E-96 T 31-10-2018 IPR035906 MetI-like superfamily AF_0093 b2f8d86b2b6613b6eca5b8a4368e6d04 261 SUPERFAMILY SSF161098 2 249 1.12E-52 T 31-10-2018 IPR035906 MetI-like superfamily AF_0521 bd669b4958d6863e4e5abe7bccef26ae 147 SUPERFAMILY SSF55729 2 134 1.72E-30 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase AF_0521 bd669b4958d6863e4e5abe7bccef26ae 147 Pfam PF00583 Acetyltransferase (GNAT) family 13 132 1.6E-21 T 31-10-2018 IPR000182 GNAT domain AF_0521 bd669b4958d6863e4e5abe7bccef26ae 147 Gene3D G3DSA:3.40.630.30 1 139 1.2E-39 T 31-10-2018 AF_0240 3cc6cc0eed63fc7e58f6e991f574167b 556 SUPERFAMILY SSF51556 75 314 3.15E-27 T 31-10-2018 IPR032466 Metal-dependent hydrolase AF_0240 3cc6cc0eed63fc7e58f6e991f574167b 556 TIGRFAM TIGR01178 ade: adenine deaminase 25 553 7.4E-242 T 31-10-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 AF_0240 3cc6cc0eed63fc7e58f6e991f574167b 556 Pfam PF01979 Amidohydrolase family 72 345 2.4E-26 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AF_0240 3cc6cc0eed63fc7e58f6e991f574167b 556 Pfam PF13382 Adenine deaminase C-terminal domain 398 548 6.2E-61 T 31-10-2018 IPR026912 Adenine deaminase C-terminal domain KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 AF_0240 3cc6cc0eed63fc7e58f6e991f574167b 556 SUPERFAMILY SSF51338 16 330 2.39E-13 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AF_0240 3cc6cc0eed63fc7e58f6e991f574167b 556 Gene3D G3DSA:2.30.40.10 17 345 1.3E-120 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AF_0240 3cc6cc0eed63fc7e58f6e991f574167b 556 Gene3D G3DSA:3.20.20.140 75 312 1.3E-120 T 31-10-2018 AF_0240 3cc6cc0eed63fc7e58f6e991f574167b 556 Hamap MF_01518 Adenine deaminase [ade]. 25 552 37.634 T 31-10-2018 IPR006679 Adenine deaminase GO:0000034|GO:0006146 KEGG: 00230+3.5.4.2|MetaCyc: PWY-6610 AF_1316 03a7473bf8fc8a27f1cf04061a09cf2c 396 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 63 364 1.5E-80 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AF_1316 03a7473bf8fc8a27f1cf04061a09cf2c 396 ProSitePatterns PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site. 90 104 - T 31-10-2018 IPR000634 Serine/threonine dehydratase, pyridoxal-phosphate-binding site GO:0006520|GO:0030170 AF_1316 03a7473bf8fc8a27f1cf04061a09cf2c 396 Gene3D G3DSA:3.40.50.1100 99 195 5.7E-132 T 31-10-2018 AF_1316 03a7473bf8fc8a27f1cf04061a09cf2c 396 TIGRFAM TIGR00260 thrC: threonine synthase 48 371 2.9E-119 T 31-10-2018 IPR004450 Threonine synthase-like AF_1316 03a7473bf8fc8a27f1cf04061a09cf2c 396 Gene3D G3DSA:3.40.50.1100 47 374 5.7E-132 T 31-10-2018 AF_1316 03a7473bf8fc8a27f1cf04061a09cf2c 396 PIRSF PIRSF038945 26 396 2.6E-172 T 31-10-2018 IPR026260 Threonine synthase, bacterial/archaeal GO:0004795|GO:0009088 KEGG: 00260+4.2.3.1|KEGG: 00750+4.2.3.1 AF_1316 03a7473bf8fc8a27f1cf04061a09cf2c 396 SUPERFAMILY SSF53686 2 383 6.42E-116 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AF_0130 39199cd220693795128cbe0385c4be2d 359 SUPERFAMILY SSF52768 3 358 3.41E-111 T 31-10-2018 IPR023696 Ureohydrolase domain superfamily AF_0130 39199cd220693795128cbe0385c4be2d 359 Pfam PF00850 Histone deacetylase domain 20 296 5.2E-81 T 31-10-2018 IPR023801 Histone deacetylase domain Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_0130 39199cd220693795128cbe0385c4be2d 359 PRINTS PR01271 Histone deacetylase signature 217 235 1.1E-7 T 31-10-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 AF_0130 39199cd220693795128cbe0385c4be2d 359 PRINTS PR01271 Histone deacetylase signature 200 213 1.1E-7 T 31-10-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 AF_0130 39199cd220693795128cbe0385c4be2d 359 PRINTS PR01271 Histone deacetylase signature 57 75 1.1E-7 T 31-10-2018 IPR003084 Histone deacetylase GO:0004407|GO:0016575 Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862|Reactome: R-HSA-3214815 AF_0130 39199cd220693795128cbe0385c4be2d 359 Gene3D G3DSA:3.40.800.20 2 358 1.2E-110 T 31-10-2018 IPR037138 Histone deacetylase domain superfamily Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_0130 39199cd220693795128cbe0385c4be2d 359 PRINTS PR01270 Histone deacetylase superfamily signature 122 145 5.0E-15 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_0130 39199cd220693795128cbe0385c4be2d 359 PRINTS PR01270 Histone deacetylase superfamily signature 239 249 5.0E-15 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_0130 39199cd220693795128cbe0385c4be2d 359 PRINTS PR01270 Histone deacetylase superfamily signature 155 170 5.0E-15 T 31-10-2018 IPR000286 Histone deacetylase family Reactome: R-HSA-2122947|Reactome: R-HSA-2644606|Reactome: R-HSA-2894862 AF_0494 180833c1905003d53b2ea09918477b41 259 Pfam PF01138 3' exoribonuclease family, domain 1 31 166 2.9E-29 T 31-10-2018 IPR001247 Exoribonuclease, phosphorolytic domain 1 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AF_0494 180833c1905003d53b2ea09918477b41 259 Hamap MF_00622 Exosome complex component Rrp42 [rrp42]. 2 259 43.776 T 31-10-2018 IPR020869 Exosome complex component Rrp42, archaea GO:0000178|GO:0006401 AF_0494 180833c1905003d53b2ea09918477b41 259 SUPERFAMILY SSF54211 6 204 3.14E-52 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AF_0494 180833c1905003d53b2ea09918477b41 259 SUPERFAMILY SSF55666 179 256 9.12E-20 T 31-10-2018 IPR036345 Exoribonuclease, PH domain 2 superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AF_0494 180833c1905003d53b2ea09918477b41 259 Gene3D G3DSA:3.30.230.70 7 259 6.6E-83 T 31-10-2018 IPR027408 PNPase/RNase PH domain superfamily Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AF_0494 180833c1905003d53b2ea09918477b41 259 Pfam PF03725 3' exoribonuclease family, domain 2 182 245 3.1E-12 T 31-10-2018 IPR015847 Exoribonuclease, phosphorolytic domain 2 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AF_1372 6354690113f7b0120f623b2005088a34 458 ProSitePatterns PS00508 Nickel-dependent hydrogenases large subunit signature 2. 411 420 - T 31-10-2018 IPR018194 Nickel-dependent hydrogenase, large subunit, nickel binding site GO:0008901|GO:0016151|GO:0055114 AF_1372 6354690113f7b0120f623b2005088a34 458 Pfam PF00374 Nickel-dependent hydrogenase 274 420 4.2E-11 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 AF_1372 6354690113f7b0120f623b2005088a34 458 Pfam PF00374 Nickel-dependent hydrogenase 38 117 6.5E-14 T 31-10-2018 IPR001501 Nickel-dependent hydrogenase, large subunit GO:0016151 AF_1372 6354690113f7b0120f623b2005088a34 458 SUPERFAMILY SSF56762 1 420 1.26E-94 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1372 6354690113f7b0120f623b2005088a34 458 Gene3D G3DSA:1.10.645.10 1 420 7.6E-98 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_0330 4426169dd0846f8818a989532ac7aade 160 PIRSF PIRSF005785 1 160 1.2E-57 T 31-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 AF_0330 4426169dd0846f8818a989532ac7aade 160 Hamap MF_01842 Archaemetzincin [amzA]. 1 159 33.373 T 31-10-2018 IPR012091 Peptidase M54, archaemetzincin, archaeal/bacterial GO:0006508|GO:0008237|GO:0008270 AF_0330 4426169dd0846f8818a989532ac7aade 160 Pfam PF07998 Peptidase family M54 64 159 2.1E-31 T 31-10-2018 IPR012962 Peptidase M54, archaemetzincin GO:0008270 AF_0330 4426169dd0846f8818a989532ac7aade 160 SUPERFAMILY SSF55486 64 151 1.2E-12 T 31-10-2018 AF_0330 4426169dd0846f8818a989532ac7aade 160 Gene3D G3DSA:3.40.390.10 1 160 2.1E-64 T 31-10-2018 IPR024079 Metallopeptidase, catalytic domain superfamily GO:0008237 AF_1825 c6ee4ad385a2cd32c68942c98db1d02e 487 Pfam PF00361 Proton-conducting membrane transporter 138 414 4.4E-51 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1825 c6ee4ad385a2cd32c68942c98db1d02e 487 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 237 261 1.2E-14 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1825 c6ee4ad385a2cd32c68942c98db1d02e 487 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 174 198 1.2E-14 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1825 c6ee4ad385a2cd32c68942c98db1d02e 487 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 144 163 1.2E-14 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1825 c6ee4ad385a2cd32c68942c98db1d02e 487 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 323 342 1.2E-14 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1825 c6ee4ad385a2cd32c68942c98db1d02e 487 PRINTS PR01437 NADH-ubiquinone oxidoreductase subunit 4 signature 375 401 1.2E-14 T 31-10-2018 IPR003918 NADH:ubiquinone oxidoreductase GO:0008137|GO:0042773|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_0794 9bbeed525c508bdddb90e293e015e849 335 Gene3D G3DSA:1.20.58.220 135 232 1.5E-9 T 31-10-2018 IPR038078 PhoU-like domain superfamily AF_0794 9bbeed525c508bdddb90e293e015e849 335 SUPERFAMILY SSF89447 11 51 2.96E-5 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily AF_0794 9bbeed525c508bdddb90e293e015e849 335 Pfam PF01895 PhoU domain 138 225 5.7E-12 T 31-10-2018 IPR026022 PhoU domain AF_0794 9bbeed525c508bdddb90e293e015e849 335 SMART SM00966 8 53 5.5E-7 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AF_0794 9bbeed525c508bdddb90e293e015e849 335 SUPERFAMILY SSF109755 126 312 1.27E-19 T 31-10-2018 AF_0794 9bbeed525c508bdddb90e293e015e849 335 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 10 49 5.8E-9 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AF_2074 4d031bec0b4959f15c88ff01e9352664 210 Hamap MF_00097 Thiamine-phosphate synthase [thiE]. 8 204 28.899 T 31-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AF_2074 4d031bec0b4959f15c88ff01e9352664 210 SUPERFAMILY SSF51391 6 206 2.35E-64 T 31-10-2018 IPR036206 Thiamin phosphate synthase superfamily KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AF_2074 4d031bec0b4959f15c88ff01e9352664 210 Gene3D G3DSA:3.20.20.70 1 206 1.0E-68 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_2074 4d031bec0b4959f15c88ff01e9352664 210 Pfam PF02581 Thiamine monophosphate synthase 10 186 7.0E-62 T 31-10-2018 IPR022998 Thiamine phosphate synthase/TenI KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AF_2074 4d031bec0b4959f15c88ff01e9352664 210 TIGRFAM TIGR00693 thiE: thiamine-phosphate diphosphorylase 9 199 2.2E-63 T 31-10-2018 IPR034291 Thiamine phosphate synthase GO:0004789|GO:0009228 KEGG: 00730+2.5.1.3|MetaCyc: PWY-6893|MetaCyc: PWY-6894|MetaCyc: PWY-6897|MetaCyc: PWY-6907|MetaCyc: PWY-6908|MetaCyc: PWY-7356|MetaCyc: PWY-7357 AF_1667 162c99aa0498c23c5e2db2745df2553b 459 Gene3D G3DSA:3.40.50.620 199 425 6.1E-67 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_1667 162c99aa0498c23c5e2db2745df2553b 459 Pfam PF14306 PUA-like domain 11 187 2.1E-31 T 31-10-2018 IPR025980 ATP-sulfurylase PUA-like domain KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AF_1667 162c99aa0498c23c5e2db2745df2553b 459 Gene3D G3DSA:3.10.400.10 10 186 1.2E-26 T 31-10-2018 AF_1667 162c99aa0498c23c5e2db2745df2553b 459 SUPERFAMILY SSF52374 195 426 1.48E-60 T 31-10-2018 AF_1667 162c99aa0498c23c5e2db2745df2553b 459 TIGRFAM TIGR00339 sopT: sulfate adenylyltransferase 12 425 4.7E-156 T 31-10-2018 IPR002650 Sulphate adenylyltransferase GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AF_1667 162c99aa0498c23c5e2db2745df2553b 459 Hamap MF_00066 Sulfate adenylyltransferase [sat]. 41 429 43.53 T 31-10-2018 IPR020792 Sulphate adenylyltransferase, prokaryotic-type GO:0000103|GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932 AF_1667 162c99aa0498c23c5e2db2745df2553b 459 SUPERFAMILY SSF88697 11 192 5.07E-32 T 31-10-2018 IPR015947 PUA-like superfamily AF_1667 162c99aa0498c23c5e2db2745df2553b 459 Pfam PF01747 ATP-sulfurylase 197 426 2.0E-69 T 31-10-2018 IPR024951 Sulphate adenylyltransferase catalytic domain GO:0004781 KEGG: 00230+2.7.7.4|KEGG: 00261+2.7.7.4|KEGG: 00450+2.7.7.4|KEGG: 00920+2.7.7.4|MetaCyc: PWY-5278|MetaCyc: PWY-5340|MetaCyc: PWY-6683|MetaCyc: PWY-6932|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AF_0900 b19adae323f1a01019457ff00673bd44 305 Gene3D G3DSA:3.40.1350.10 214 305 6.9E-37 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 AF_0900 b19adae323f1a01019457ff00673bd44 305 SUPERFAMILY SSF53032 62 138 1.7E-16 T 31-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 AF_0900 b19adae323f1a01019457ff00673bd44 305 Gene3D G3DSA:3.40.1170.20 139 213 3.3E-25 T 31-10-2018 AF_0900 b19adae323f1a01019457ff00673bd44 305 SUPERFAMILY SSF55267 3 60 3.01E-33 T 31-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 AF_0900 b19adae323f1a01019457ff00673bd44 305 Pfam PF01974 tRNA intron endonuclease, catalytic C-terminal domain 216 294 2.4E-23 T 31-10-2018 IPR006677 tRNA intron endonuclease, catalytic domain-like GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 AF_0900 b19adae323f1a01019457ff00673bd44 305 TIGRFAM TIGR00324 endA: tRNA-intron lyase 148 301 3.7E-51 T 31-10-2018 IPR006676 tRNA-splicing endonuclease GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 AF_0900 b19adae323f1a01019457ff00673bd44 305 Pfam PF02778 tRNA intron endonuclease, N-terminal domain 151 203 1.2E-6 T 31-10-2018 IPR006678 tRNA intron endonuclease, N-terminal GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 AF_0900 b19adae323f1a01019457ff00673bd44 305 SUPERFAMILY SSF53032 215 295 8.72E-22 T 31-10-2018 IPR036167 tRNA intron endonuclease, catalytic domain-like superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803|Reactome: R-HSA-6784531 AF_0900 b19adae323f1a01019457ff00673bd44 305 SUPERFAMILY SSF55267 141 213 2.62E-18 T 31-10-2018 IPR036740 tRNA intron endonuclease, N-terminal domain superfamily GO:0000213|GO:0006388 MetaCyc: PWY-6689|MetaCyc: PWY-7803 AF_0900 b19adae323f1a01019457ff00673bd44 305 Gene3D G3DSA:3.40.1350.150 1 138 9.6E-57 T 31-10-2018 AF_0900 b19adae323f1a01019457ff00673bd44 305 Hamap MF_01834 tRNA-splicing endonuclease [endA]. 1 305 32.334 T 31-10-2018 IPR023516 tRNA-splicing endonuclease, archaeal long subfamily GO:0000213 MetaCyc: PWY-6689|MetaCyc: PWY-7803 AF_2234 5c0914e30007133631dbe0d4f10efc9b 67 Pfam PF10967 Protein of unknown function (DUF2769) 12 64 1.0E-14 T 31-10-2018 IPR020075 Uncharacterised protein family AF2234 AF_2234 5c0914e30007133631dbe0d4f10efc9b 67 ProDom PD054827 AF2234 MA2973 PREDICTED 12 67 9.0E-26 T 31-10-2018 IPR020075 Uncharacterised protein family AF2234 AF_1058 bb4e743d3047ea188d7da68fd0bd7f93 118 Gene3D G3DSA:1.20.1500.10 2 115 7.1E-20 T 31-10-2018 IPR023378 YheA/YmcA-like domain superfamily AF_1058 bb4e743d3047ea188d7da68fd0bd7f93 118 Pfam PF06133 Control of competence regulator ComK, YlbF/YmcA 6 109 3.7E-20 T 31-10-2018 IPR010368 Control of competence regulator ComK, YlbF/YmcA AF_1058 bb4e743d3047ea188d7da68fd0bd7f93 118 SUPERFAMILY SSF158622 6 109 1.83E-21 T 31-10-2018 IPR023378 YheA/YmcA-like domain superfamily AF_0512 251dad1d4258f2347f05d003f66284db 205 Pfam PF08241 Methyltransferase domain 50 143 6.8E-23 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AF_0512 251dad1d4258f2347f05d003f66284db 205 SUPERFAMILY SSF53335 14 193 4.76E-41 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_0512 251dad1d4258f2347f05d003f66284db 205 Gene3D G3DSA:3.40.50.150 12 198 6.7E-38 T 31-10-2018 AF_2300 44bf8de8611e8a346ed101a268d8e317 298 SUPERFAMILY SSF52467 1 288 1.01E-93 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AF_2300 44bf8de8611e8a346ed101a268d8e317 298 Hamap MF_00153 Probable deoxyhypusine synthase [dys]. 1 285 40.419 T 31-10-2018 IPR022899 Deoxyhypusine synthase, putative, archaeal GO:0034038 AF_2300 44bf8de8611e8a346ed101a268d8e317 298 TIGRFAM TIGR00321 dhys: deoxyhypusine synthase 1 285 9.6E-127 T 31-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 AF_2300 44bf8de8611e8a346ed101a268d8e317 298 Gene3D G3DSA:3.40.910.10 1 292 8.3E-97 T 31-10-2018 IPR036982 Deoxyhypusine synthase superfamily GO:0008612 Reactome: R-HSA-204626 AF_2300 44bf8de8611e8a346ed101a268d8e317 298 Pfam PF01916 Deoxyhypusine synthase 1 282 1.6E-97 T 31-10-2018 IPR002773 Deoxyhypusine synthase GO:0008612 Reactome: R-HSA-204626 AF_2388 19239761dd8e96f9b13e4fc1d3326800 384 SUPERFAMILY SSF161111 3 202 2.09E-54 T 31-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AF_2388 19239761dd8e96f9b13e4fc1d3326800 384 Gene3D G3DSA:1.20.1510.10 5 201 5.9E-55 T 31-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AF_2388 19239761dd8e96f9b13e4fc1d3326800 384 Gene3D G3DSA:3.30.70.1350 202 281 1.1E-7 T 31-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AF_2388 19239761dd8e96f9b13e4fc1d3326800 384 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 6 280 5.9E-77 T 31-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AF_2388 19239761dd8e96f9b13e4fc1d3326800 384 SUPERFAMILY SSF160240 204 278 3.4E-9 T 31-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AF_2388 19239761dd8e96f9b13e4fc1d3326800 384 Gene3D G3DSA:3.30.420.130 301 384 3.5E-10 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily AF_2388 19239761dd8e96f9b13e4fc1d3326800 384 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 302 383 7.2E-16 T 31-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis AF_2388 19239761dd8e96f9b13e4fc1d3326800 384 SUPERFAMILY SSF53146 303 381 2.35E-11 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily AF_2388 19239761dd8e96f9b13e4fc1d3326800 384 Pfam PF01545 Cation efflux family 10 201 1.6E-42 T 31-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AF_2388 19239761dd8e96f9b13e4fc1d3326800 384 Pfam PF16916 Dimerisation domain of Zinc Transporter 205 277 7.8E-8 T 31-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain AF_0991 5a866e2c60deaf18805539e47dd5aab4 395 SUPERFAMILY SSF56645 4 236 1.57E-74 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AF_0991 5a866e2c60deaf18805539e47dd5aab4 395 SUPERFAMILY SSF47203 242 388 9.34E-43 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AF_0991 5a866e2c60deaf18805539e47dd5aab4 395 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 237 384 1.1E-37 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AF_0991 5a866e2c60deaf18805539e47dd5aab4 395 Gene3D G3DSA:1.20.140.10 242 395 9.0E-42 T 31-10-2018 AF_0991 5a866e2c60deaf18805539e47dd5aab4 395 Gene3D G3DSA:2.40.110.10 132 237 1.3E-35 T 31-10-2018 AF_0991 5a866e2c60deaf18805539e47dd5aab4 395 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 133 222 1.0E-21 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AF_0991 5a866e2c60deaf18805539e47dd5aab4 395 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 15 129 2.6E-31 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AF_0991 5a866e2c60deaf18805539e47dd5aab4 395 Gene3D G3DSA:1.10.540.10 2 130 1.4E-35 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AF_1762 c80bf3061429f5e19ebc259b812a5d57 61 SUPERFAMILY SSF52096 2 32 2.24E-5 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AF_1762 c80bf3061429f5e19ebc259b812a5d57 61 Gene3D G3DSA:3.30.300.220 1 50 3.0E-5 T 31-10-2018 AF_1369 9f8df824506e95eabfb76856ed81e42c 77 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 2 9 1.2E-16 T 31-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AF_1369 9f8df824506e95eabfb76856ed81e42c 77 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 17 33 1.2E-16 T 31-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AF_1369 9f8df824506e95eabfb76856ed81e42c 77 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 38 54 1.2E-16 T 31-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AF_1369 9f8df824506e95eabfb76856ed81e42c 77 PRINTS PR00445 HupF/HypC hydrogenase expression/synthesis family signature 56 68 1.2E-16 T 31-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AF_1369 9f8df824506e95eabfb76856ed81e42c 77 Gene3D G3DSA:2.40.50.970 1 73 6.7E-29 T 31-10-2018 IPR037254 HupF/HypC superfamily AF_1369 9f8df824506e95eabfb76856ed81e42c 77 SUPERFAMILY SSF159127 1 73 1.23E-24 T 31-10-2018 IPR037254 HupF/HypC superfamily AF_1369 9f8df824506e95eabfb76856ed81e42c 77 ProSitePatterns PS01097 Hydrogenases expression/synthesis hupF/hypC family signature. 1 9 - T 31-10-2018 IPR019812 Hydrogenase assembly chaperone, conserved site AF_1369 9f8df824506e95eabfb76856ed81e42c 77 TIGRFAM TIGR00074 hypC_hupF: hydrogenase assembly chaperone HypC/HupF 1 75 1.7E-30 T 31-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AF_1369 9f8df824506e95eabfb76856ed81e42c 77 Pfam PF01455 HupF/HypC family 1 65 1.5E-27 T 31-10-2018 IPR001109 Hydrogenase expression/formation protein, HupF/HypC AF_0850 0a50b1af8511df22b8e3198e5084b9c9 337 PIRSF PIRSF009433 1 337 4.6E-135 T 31-10-2018 IPR009927 Protein of unknown function DUF1464 AF_0850 0a50b1af8511df22b8e3198e5084b9c9 337 Pfam PF07318 Protein of unknown function (DUF1464) 5 321 2.6E-127 T 31-10-2018 IPR009927 Protein of unknown function DUF1464 AF_0860 8d80b3f23081406f1cd5e4d8610ce307 89 Pfam PF04981 NMD3 family 6 83 2.0E-8 T 31-10-2018 IPR007064 Nmd3, N-terminal AF_1876 976aa1a5579367a7f943ddbce7fbb69f 94 Hamap MF_01471 CRISPR-associated endoribonuclease Cas2 [cas2]. 1 86 17.422 T 31-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 AF_1876 976aa1a5579367a7f943ddbce7fbb69f 94 SUPERFAMILY SSF143430 1 79 9.68E-21 T 31-10-2018 AF_1876 976aa1a5579367a7f943ddbce7fbb69f 94 TIGRFAM TIGR01573 cas2: CRISPR-associated endonuclease Cas2 1 93 2.5E-28 T 31-10-2018 IPR021127 CRISPR-associated endonuclease Cas2 GO:0004521|GO:0043571 AF_1876 976aa1a5579367a7f943ddbce7fbb69f 94 Gene3D G3DSA:3.30.70.240 2 67 2.4E-23 T 31-10-2018 AF_1876 976aa1a5579367a7f943ddbce7fbb69f 94 Pfam PF09827 CRISPR associated protein Cas2 1 73 1.6E-20 T 31-10-2018 IPR019199 Virulence-associated protein D / CRISPR associated protein Cas2 AF_0684 f13f132ba0efc671e1a9fd95aa2f3db6 117 Gene3D G3DSA:1.20.1300.10 5 117 2.7E-19 T 31-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_0684 f13f132ba0efc671e1a9fd95aa2f3db6 117 Pfam PF01127 Succinate dehydrogenase/Fumarate reductase transmembrane subunit 14 107 1.9E-16 T 31-10-2018 IPR000701 Succinate dehydrogenase/fumarate reductase type B, transmembrane subunit GO:0016627 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_0684 f13f132ba0efc671e1a9fd95aa2f3db6 117 PIRSF PIRSF000178 14 117 4.7E-7 T 31-10-2018 IPR014314 Succinate dehydrogenase, cytochrome b556 subunit GO:0000104|GO:0006099|GO:0045281 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_0684 f13f132ba0efc671e1a9fd95aa2f3db6 117 SUPERFAMILY SSF81343 11 116 3.71E-22 T 31-10-2018 IPR034804 Fumarate reductase/succinate dehydrogenase, transmembrane subunit GO:0016020 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_0316 39824e9280e967ba41a95057b513783d 113 SUPERFAMILY SSF141694 50 110 4.71E-15 T 31-10-2018 AF_0316 39824e9280e967ba41a95057b513783d 113 Gene3D G3DSA:4.10.1150.10 50 112 4.9E-16 T 31-10-2018 IPR024069 AF2212-like domain superfamily AF_0316 39824e9280e967ba41a95057b513783d 113 Pfam PF01954 Protein of unknown function DUF104 50 108 4.6E-24 T 31-10-2018 IPR008203 Uncharacterised protein family UPF0165 AF_0751 14e5982bd645091d164ee7767103ccf1 168 Gene3D G3DSA:3.40.1280.10 1 168 4.4E-80 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AF_0751 14e5982bd645091d164ee7767103ccf1 168 SUPERFAMILY SSF75217 1 166 1.83E-70 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases AF_0751 14e5982bd645091d164ee7767103ccf1 168 ProDom PD016584 UPF0106 MK0803 MM0086 METAL MA3241 UNCHARACTERIZED DOMAIN TA0931 APE2006 ST0333 51 166 2.0E-61 T 31-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 AF_0751 14e5982bd645091d164ee7767103ccf1 168 PIRSF PIRSF016123 1 168 8.7E-79 T 31-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 AF_0751 14e5982bd645091d164ee7767103ccf1 168 Pfam PF01994 tRNA ribose 2'-O-methyltransferase, aTrm56 54 166 8.9E-43 T 31-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 AF_0751 14e5982bd645091d164ee7767103ccf1 168 Hamap MF_00077 tRNA (cytidine(56)-2'-O)-methyltransferase. 2 168 40.496 T 31-10-2018 IPR002845 tRNA ribose 2'-O-methyltransferase, aTrm56 GO:0002128|GO:0005737|GO:0008175 AF_2215 af4345fa301f59a9fd86a57af616389e 548 Gene3D G3DSA:3.20.20.240 1 548 7.6E-274 T 31-10-2018 AF_2215 af4345fa301f59a9fd86a57af616389e 548 SUPERFAMILY SSF51703 3 542 2.35E-232 T 31-10-2018 IPR016176 Cobalamin (vitamin B12)-dependent enzyme, catalytic GO:0003824|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AF_2215 af4345fa301f59a9fd86a57af616389e 548 Pfam PF01642 Methylmalonyl-CoA mutase 26 540 8.7E-245 T 31-10-2018 IPR006099 Methylmalonyl-CoA mutase, alpha/beta chain, catalytic GO:0016866|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AF_2215 af4345fa301f59a9fd86a57af616389e 548 TIGRFAM TIGR00641 acid_CoA_mut_N: methylmalonyl-CoA mutase N-terminal domain 25 547 1.6E-290 T 31-10-2018 IPR006098 Methylmalonyl-CoA mutase, alpha chain, catalytic GO:0004494|GO:0031419 Reactome: R-HSA-196741|Reactome: R-HSA-3359475|Reactome: R-HSA-3359478|Reactome: R-HSA-71032 AF_1364 e86558f2cf74005a295c1b4bf0ffe21d 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 4 24 1.2E-30 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 AF_1364 e86558f2cf74005a295c1b4bf0ffe21d 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 25 43 1.2E-30 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 AF_1364 e86558f2cf74005a295c1b4bf0ffe21d 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 89 107 1.2E-30 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 AF_1364 e86558f2cf74005a295c1b4bf0ffe21d 388 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 72 87 1.2E-30 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 AF_1364 e86558f2cf74005a295c1b4bf0ffe21d 388 Gene3D G3DSA:3.10.20.30 310 387 5.0E-33 T 31-10-2018 IPR012675 Beta-grasp domain superfamily AF_1364 e86558f2cf74005a295c1b4bf0ffe21d 388 SUPERFAMILY SSF52540 2 304 6.85E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1364 e86558f2cf74005a295c1b4bf0ffe21d 388 Gene3D G3DSA:1.10.8.470 125 210 5.1E-21 T 31-10-2018 AF_1364 e86558f2cf74005a295c1b4bf0ffe21d 388 Pfam PF01926 50S ribosome-binding GTPase 3 115 1.7E-20 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 AF_1364 e86558f2cf74005a295c1b4bf0ffe21d 388 SUPERFAMILY SSF81271 312 385 1.23E-18 T 31-10-2018 IPR012676 TGS-like KEGG: 00970+6.1.1.3 AF_1364 e86558f2cf74005a295c1b4bf0ffe21d 388 Pfam PF08438 GTPase of unknown function C-terminal 216 318 4.3E-36 T 31-10-2018 IPR013646 Uncharacterised GTP-binding protein, C-terminal AF_1364 e86558f2cf74005a295c1b4bf0ffe21d 388 Pfam PF02824 TGS domain 328 384 3.4E-14 T 31-10-2018 IPR004095 TGS KEGG: 00970+6.1.1.3 AF_0201 42afdc574f81fe48cfe61d5cbebd1283 368 PIRSF PIRSF000429 15 367 3.9E-11 T 31-10-2018 IPR002155 Thiolase GO:0016747 AF_0201 42afdc574f81fe48cfe61d5cbebd1283 368 Gene3D G3DSA:3.40.47.10 14 368 1.8E-62 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0201 42afdc574f81fe48cfe61d5cbebd1283 368 SUPERFAMILY SSF53901 234 365 2.11E-13 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0201 42afdc574f81fe48cfe61d5cbebd1283 368 SUPERFAMILY SSF53901 21 232 5.45E-14 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0471 beb128c52562d39430aaa1ccc729328a 187 Gene3D G3DSA:3.40.920.10 2 171 4.6E-44 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AF_0471 beb128c52562d39430aaa1ccc729328a 187 SUPERFAMILY SSF53323 5 177 1.44E-30 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AF_0471 beb128c52562d39430aaa1ccc729328a 187 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 13 166 5.9E-32 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AF_0653 40605d19644c910b9e13b6650f1fb940 96 SUPERFAMILY SSF46785 27 93 8.59E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0653 40605d19644c910b9e13b6650f1fb940 96 Pfam PF01022 Bacterial regulatory protein, arsR family 26 67 1.8E-11 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_0653 40605d19644c910b9e13b6650f1fb940 96 Gene3D G3DSA:1.10.10.10 20 96 6.3E-12 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1149 bce2e9f536e22d25ec0652256379fb70 892 SMART SM00490 260 337 6.3E-19 T 31-10-2018 IPR001650 Helicase, C-terminal AF_1149 bce2e9f536e22d25ec0652256379fb70 892 SMART SM00487 14 214 6.2E-43 T 31-10-2018 IPR014001 Helicase superfamily 1/2, ATP-binding domain AF_1149 bce2e9f536e22d25ec0652256379fb70 892 Gene3D G3DSA:3.40.50.300 222 368 4.3E-30 T 31-10-2018 AF_1149 bce2e9f536e22d25ec0652256379fb70 892 Gene3D G3DSA:3.40.50.300 1 205 5.4E-51 T 31-10-2018 AF_1149 bce2e9f536e22d25ec0652256379fb70 892 Pfam PF00271 Helicase conserved C-terminal domain 241 337 1.2E-19 T 31-10-2018 IPR001650 Helicase, C-terminal AF_1149 bce2e9f536e22d25ec0652256379fb70 892 SUPERFAMILY SSF52540 28 348 3.16E-52 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1149 bce2e9f536e22d25ec0652256379fb70 892 Pfam PF00270 DEAD/DEAH box helicase 19 185 6.6E-34 T 31-10-2018 IPR011545 DEAD/DEAH box helicase domain GO:0003676|GO:0005524 AF_1149 bce2e9f536e22d25ec0652256379fb70 892 PIRSF PIRSF037307 1 892 0.0 T 31-10-2018 IPR017170 Lhr-like ATP-dependent RNA helicase, predicted GO:0005524|GO:0016818 AF_1149 bce2e9f536e22d25ec0652256379fb70 892 Pfam PF08494 DEAD/H associated 582 750 1.5E-30 T 31-10-2018 IPR013701 DEAD/H associated GO:0005524|GO:0016818 AF_2334 bdef8a0f74e103c4a61afb78f125bf05 269 TIGRFAM TIGR00417 speE: spermidine synthase 3 260 7.9E-110 T 31-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AF_2334 bdef8a0f74e103c4a61afb78f125bf05 269 Gene3D G3DSA:2.30.140.10 1 51 2.4E-17 T 31-10-2018 IPR037163 Spermidine synthase, tetramerisation domain superfamily KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AF_2334 bdef8a0f74e103c4a61afb78f125bf05 269 SUPERFAMILY SSF53335 3 265 9.36E-59 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_2334 bdef8a0f74e103c4a61afb78f125bf05 269 Pfam PF17284 Spermidine synthase tetramerisation domain 2 52 4.0E-19 T 31-10-2018 IPR035246 Spermidine synthase, tetramerisation domain KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AF_2334 bdef8a0f74e103c4a61afb78f125bf05 269 Gene3D G3DSA:3.40.50.150 52 267 2.2E-57 T 31-10-2018 AF_2334 bdef8a0f74e103c4a61afb78f125bf05 269 Pfam PF01564 Spermine/spermidine synthase domain 56 227 9.9E-57 T 31-10-2018 AF_2334 bdef8a0f74e103c4a61afb78f125bf05 269 Hamap MF_00198 Polyamine aminopropyltransferase [speE]. 2 266 34.898 T 31-10-2018 IPR001045 Spermidine/spermine synthases GO:0003824 KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AF_2334 bdef8a0f74e103c4a61afb78f125bf05 269 ProSitePatterns PS01330 Polyamine biosynthesis (PABS) domain signature. 76 89 - T 31-10-2018 IPR030373 Polyamine biosynthesis domain, conserved site KEGG: 00270+2.5.1.16|KEGG: 00330+2.5.1.16|KEGG: 00410+2.5.1.16|KEGG: 00480+2.5.1.16|Reactome: R-HSA-351202 AF_0728 7c137da91f82f95070fc15c1aeca9b18 218 Hamap MF_01462 Cobalt transport protein CbiM [cbiM]. 2 217 28.372 T 31-10-2018 IPR018024 Cobalamin (vitamin B12) transport protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 AF_0728 7c137da91f82f95070fc15c1aeca9b18 218 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 3 211 1.2E-51 T 31-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 AF_0728 7c137da91f82f95070fc15c1aeca9b18 218 Gene3D G3DSA:1.10.1760.20 2 211 1.3E-53 T 31-10-2018 AF_0728 7c137da91f82f95070fc15c1aeca9b18 218 TIGRFAM TIGR00123 cbiM: cobalamin biosynthesis protein CbiM 2 214 5.1E-110 T 31-10-2018 IPR018024 Cobalamin (vitamin B12) transport protein CbiM GO:0006824|GO:0009236|GO:0016021|GO:0043190 AF_0256 12b6277cb6ba7aaed8901d6a8e12cbf9 373 SUPERFAMILY SSF56059 124 373 7.42E-52 T 31-10-2018 AF_0256 12b6277cb6ba7aaed8901d6a8e12cbf9 373 PIRSF PIRSF004602 1 373 7.2E-136 T 31-10-2018 IPR023656 IMP biosynthesis enzyme PurP GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 AF_0256 12b6277cb6ba7aaed8901d6a8e12cbf9 373 Gene3D G3DSA:3.30.1490.20 138 203 1.1E-66 T 31-10-2018 IPR013815 ATP-grasp fold, subdomain 1 GO:0005524 AF_0256 12b6277cb6ba7aaed8901d6a8e12cbf9 373 Gene3D G3DSA:3.40.50.20 2 107 1.2E-34 T 31-10-2018 AF_0256 12b6277cb6ba7aaed8901d6a8e12cbf9 373 Pfam PF06849 Protein of unknown function (DUF1246) 15 141 1.2E-44 T 31-10-2018 IPR010672 IMP biosynthesis enzyme PurP, N-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 AF_0256 12b6277cb6ba7aaed8901d6a8e12cbf9 373 Pfam PF06973 Domain of unknown function (DUF1297) 174 373 4.2E-63 T 31-10-2018 IPR009720 IMP biosynthesis enzyme PurP, C-terminal GO:0000287|GO:0005524|GO:0006188|GO:0016879 KEGG: 00230+6.3.4.23|MetaCyc: PWY-7234 AF_0256 12b6277cb6ba7aaed8901d6a8e12cbf9 373 Gene3D G3DSA:3.30.470.20 108 372 1.1E-66 T 31-10-2018 AF_0256 12b6277cb6ba7aaed8901d6a8e12cbf9 373 SUPERFAMILY SSF52440 9 119 5.37E-38 T 31-10-2018 IPR016185 Pre-ATP-grasp domain superfamily AF_1549 ae1fb9b5907afa9b62760fea7136e10a 95 Gene3D G3DSA:3.30.70.1340 1 86 4.4E-37 T 31-10-2018 IPR023129 MTH889-like domain superfamily AF_1549 ae1fb9b5907afa9b62760fea7136e10a 95 SUPERFAMILY SSF160363 3 92 1.06E-34 T 31-10-2018 IPR023129 MTH889-like domain superfamily AF_1549 ae1fb9b5907afa9b62760fea7136e10a 95 ProDom PD012512 ARCHAEA PH1931 STS176 TA1183 MJ0319 PRECURSOR TVG0378908 UNCHARACTERIZED DUF211 AF1549 11 94 2.0E-40 T 31-10-2018 IPR003831 Protein of unknown function DUF211 AF_1549 ae1fb9b5907afa9b62760fea7136e10a 95 Pfam PF02680 Uncharacterized ArCR, COG1888 4 90 1.8E-38 T 31-10-2018 IPR003831 Protein of unknown function DUF211 AF_0190 958a18cdbc68d51efa192b8c36278498 184 Gene3D G3DSA:1.10.760.10 69 184 3.5E-11 T 31-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AF_0190 958a18cdbc68d51efa192b8c36278498 184 Pfam PF13442 Cytochrome C oxidase, cbb3-type, subunit III 105 180 2.2E-7 T 31-10-2018 IPR009056 Cytochrome c-like domain GO:0009055|GO:0020037 Reactome: R-HSA-111457|Reactome: R-HSA-111458|Reactome: R-HSA-111459|Reactome: R-HSA-2151201|Reactome: R-HSA-3299685|Reactome: R-HSA-5628897|Reactome: R-HSA-611105 AF_0190 958a18cdbc68d51efa192b8c36278498 184 SUPERFAMILY SSF46626 15 183 6.3E-12 T 31-10-2018 IPR036909 Cytochrome c-like domain superfamily GO:0009055|GO:0020037 Reactome: R-HSA-611105 AF_2396 0e67ce6633c1779478b1bea98734f9a4 78 Pfam PF04023 FeoA domain 4 73 4.7E-17 T 31-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 AF_2396 0e67ce6633c1779478b1bea98734f9a4 78 SMART SM00899 4 74 8.8E-17 T 31-10-2018 IPR007167 Ferrous iron transporter FeoA domain GO:0046914 AF_2396 0e67ce6633c1779478b1bea98734f9a4 78 SUPERFAMILY SSF50037 6 73 2.75E-13 T 31-10-2018 IPR008988 Transcriptional repressor, C-terminal AF_2396 0e67ce6633c1779478b1bea98734f9a4 78 Gene3D G3DSA:2.30.30.90 4 77 7.2E-18 T 31-10-2018 IPR038157 Ferrous iron transporter, core domain AF_1947 faf3e2bd033adee412474044251bf210 212 Pfam PF03891 Domain of unknown function (DUF333) 21 65 2.7E-14 T 31-10-2018 IPR005590 Protein of unknown function DUF333 AF_0205 e0bb80d8cd81b8340891de508001d95a 204 Pfam PF06325 Ribosomal protein L11 methyltransferase (PrmA) 47 97 4.4E-11 T 31-10-2018 AF_0205 e0bb80d8cd81b8340891de508001d95a 204 SUPERFAMILY SSF53335 3 196 1.32E-24 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_0205 e0bb80d8cd81b8340891de508001d95a 204 Gene3D G3DSA:3.40.50.150 1 200 1.7E-52 T 31-10-2018 AF_1244 4f94bc6376cd95cad910b02c5e33fa8f 161 PIRSF PIRSF005028 2 161 9.3E-49 T 31-10-2018 IPR026278 Potassium/proton antiporter subunit KhtT AF_1244 4f94bc6376cd95cad910b02c5e33fa8f 161 SUPERFAMILY SSF116726 87 159 1.7E-18 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AF_1244 4f94bc6376cd95cad910b02c5e33fa8f 161 Gene3D G3DSA:3.30.70.1450 88 160 3.5E-21 T 31-10-2018 IPR036721 Regulator of K+ conductance, C-terminal domain superfamily GO:0006813 AF_1244 4f94bc6376cd95cad910b02c5e33fa8f 161 Pfam PF02080 TrkA-C domain 95 159 9.4E-17 T 31-10-2018 IPR006037 Regulator of K+ conductance, C-terminal GO:0006813|GO:0008324 AF_1529 3e430fe0960286b58a1344c622e6b3cb 97 ProSitePatterns PS01171 Ribosomal protein L21e signature. 37 62 - T 31-10-2018 IPR018259 Ribosomal protein L21e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1529 3e430fe0960286b58a1344c622e6b3cb 97 Pfam PF01157 Ribosomal protein L21e 4 95 3.0E-30 T 31-10-2018 IPR001147 Ribosomal protein L21e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1529 3e430fe0960286b58a1344c622e6b3cb 97 SUPERFAMILY SSF50104 4 95 1.62E-30 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily AF_1529 3e430fe0960286b58a1344c622e6b3cb 97 Gene3D G3DSA:2.30.30.70 3 96 1.0E-34 T 31-10-2018 IPR036948 Ribosomal protein L21 superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1529 3e430fe0960286b58a1344c622e6b3cb 97 Hamap MF_00369 50S ribosomal protein L21e [rpl21e]. 3 96 29.18 T 31-10-2018 IPR022856 Ribosomal protein L21e, archaeal AF_0416 ff16595ae64c8426cbad084b40b14ca8 62 ProDom PD104924 XAC1607 AF0417 6 57 1.0E-4 T 31-10-2018 AF_0416 ff16595ae64c8426cbad084b40b14ca8 62 Pfam PF11655 Protein of unknown function (DUF2589) 8 55 9.6E-5 T 31-10-2018 IPR024510 Protein of unknown function DUF2589 AF_1923 c551340353ef911a50e037c25176bda0 83 TIGRFAM TIGR03636 uL23_arch: ribosomal protein uL23 9 83 1.4E-32 T 31-10-2018 IPR019985 Ribosomal protein L23 GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1923 c551340353ef911a50e037c25176bda0 83 Pfam PF00276 Ribosomal protein L23 5 68 4.2E-13 T 31-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 AF_1923 c551340353ef911a50e037c25176bda0 83 ProSitePatterns PS00050 Ribosomal protein L23 signature. 61 76 - T 31-10-2018 IPR001014 Ribosomal protein L23/L25, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1923 c551340353ef911a50e037c25176bda0 83 Hamap MF_01369_A 50S ribosomal protein L23 [rplW]. 4 83 24.037 T 31-10-2018 IPR013025 Ribosomal protein L25/L23 GO:0003735|GO:0005840|GO:0006412 AF_1923 c551340353ef911a50e037c25176bda0 83 SUPERFAMILY SSF54189 4 78 5.4E-21 T 31-10-2018 IPR012678 Ribosomal protein L23/L15e core domain superfamily GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1923 c551340353ef911a50e037c25176bda0 83 Gene3D G3DSA:3.30.70.330 2 83 1.6E-28 T 31-10-2018 IPR012677 Nucleotide-binding alpha-beta plait domain superfamily AF_2105 1c3f42544706ed79b3768b0a554438e7 89 Gene3D G3DSA:3.10.20.30 1 89 4.3E-16 T 31-10-2018 IPR012675 Beta-grasp domain superfamily AF_2105 1c3f42544706ed79b3768b0a554438e7 89 SUPERFAMILY SSF54285 2 89 1.29E-11 T 31-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AF_2105 1c3f42544706ed79b3768b0a554438e7 89 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 3 89 7.9E-15 T 31-10-2018 IPR010038 MoaD, archaeal-type AF_2105 1c3f42544706ed79b3768b0a554438e7 89 Pfam PF02597 ThiS family 5 89 1.5E-11 T 31-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 AF_0370 2b679b9cb32ea1f275a5c94727c29ded 339 Gene3D G3DSA:3.40.50.10470 142 339 5.4E-72 T 31-10-2018 AF_0370 2b679b9cb32ea1f275a5c94727c29ded 339 TIGRFAM TIGR00512 salvage_mtnA: S-methyl-5-thioribose-1-phosphate isomerase 5 326 9.6E-119 T 31-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AF_0370 2b679b9cb32ea1f275a5c94727c29ded 339 Pfam PF01008 Initiation factor 2 subunit family 42 327 2.3E-96 T 31-10-2018 IPR000649 Initiation factor 2B-related GO:0044237 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174 AF_0370 2b679b9cb32ea1f275a5c94727c29ded 339 SUPERFAMILY SSF100950 5 331 5.86E-116 T 31-10-2018 IPR037171 NagB/RpiA transferase-like AF_0370 2b679b9cb32ea1f275a5c94727c29ded 339 Gene3D G3DSA:1.20.120.420 1 140 3.3E-52 T 31-10-2018 IPR027363 Methylthioribose-1-phosphate isomerase, N-terminal KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AF_0370 2b679b9cb32ea1f275a5c94727c29ded 339 Hamap MF_01678 Putative methylthioribose-1-phosphate isomerase [mtnA]. 1 337 36.846 T 31-10-2018 IPR005251 Methylthioribose-1-phosphate isomerase GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AF_0370 2b679b9cb32ea1f275a5c94727c29ded 339 TIGRFAM TIGR00524 eIF-2B_rel: eIF-2B alpha/beta/delta-related uncharacterized proteins 27 327 2.9E-139 T 31-10-2018 IPR011559 Initiation factor 2B alpha/beta/delta GO:0044249 KEGG: 00270+5.3.1.23|MetaCyc: PWY-4361|MetaCyc: PWY-7174|Reactome: R-HSA-1237112 AF_2259 158462f9f7a2b54efd7d352975f1e018 420 Hamap MF_01892 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS [tiaS]. 3 419 37.799 T 31-10-2018 IPR024913 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS GO:0002101|GO:0016879 AF_2259 158462f9f7a2b54efd7d352975f1e018 420 Gene3D G3DSA:2.40.50.1010 250 398 3.2E-61 T 31-10-2018 AF_2259 158462f9f7a2b54efd7d352975f1e018 420 Gene3D G3DSA:3.30.70.2200 2 154 1.0E-47 T 31-10-2018 AF_2259 158462f9f7a2b54efd7d352975f1e018 420 Pfam PF08489 Domain of unknown function (DUF1743) 139 251 4.3E-41 T 31-10-2018 IPR013696 Domain of unknown function DUF1743 AF_2259 158462f9f7a2b54efd7d352975f1e018 420 Pfam PF01336 OB-fold nucleic acid binding domain 268 329 1.5E-6 T 31-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AF_2259 158462f9f7a2b54efd7d352975f1e018 420 Gene3D G3DSA:3.90.600.20 155 249 4.0E-32 T 31-10-2018 AF_1556 7313cfca14e78ff929487a819b6a1c15 274 Pfam PF06508 Queuosine biosynthesis protein QueC 28 91 4.5E-9 T 31-10-2018 IPR018317 Queuosine biosynthesis protein QueC KEGG: 00790+6.3.4.20|MetaCyc: PWY-6703 AF_1556 7313cfca14e78ff929487a819b6a1c15 274 PIRSF PIRSF006661 9 273 5.1E-107 T 31-10-2018 IPR005232 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase LarE GO:0016783 AF_1556 7313cfca14e78ff929487a819b6a1c15 274 SUPERFAMILY SSF52402 27 225 6.62E-36 T 31-10-2018 AF_1556 7313cfca14e78ff929487a819b6a1c15 274 TIGRFAM TIGR00268 TIGR00268: TIGR00268 family protein 15 269 5.1E-129 T 31-10-2018 IPR005232 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase LarE GO:0016783 AF_1556 7313cfca14e78ff929487a819b6a1c15 274 Gene3D G3DSA:3.40.50.620 11 253 1.4E-27 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_2189 ba52509d289259e450d9dda486009278 72 Pfam PF02381 MraZ protein, putative antitoxin-like 7 43 5.5E-5 T 31-10-2018 IPR020603 MraZ domain AF_2189 ba52509d289259e450d9dda486009278 72 SUPERFAMILY SSF89447 3 44 3.4E-9 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily AF_2189 ba52509d289259e450d9dda486009278 72 Gene3D G3DSA:2.10.260.10 4 43 1.5E-5 T 31-10-2018 AF_2189 ba52509d289259e450d9dda486009278 72 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 6 41 1.1E-8 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AF_2189 ba52509d289259e450d9dda486009278 72 SMART SM00966 6 46 4.5E-7 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AF_0954 e476a2ac7dd8c852bf2332e8dbc95f94 280 SUPERFAMILY SSF69336 35 278 1.02E-52 T 31-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 AF_0954 e476a2ac7dd8c852bf2332e8dbc95f94 280 Pfam PF01493 GXGXG motif 63 233 1.6E-35 T 31-10-2018 IPR002489 Glutamate synthase, alpha subunit, C-terminal GO:0016491|GO:0055114 AF_0954 e476a2ac7dd8c852bf2332e8dbc95f94 280 Gene3D G3DSA:2.160.20.60 48 274 4.2E-34 T 31-10-2018 IPR036485 Glutamate synthase, alpha subunit, C-terminal domain superfamily GO:0016491|GO:0055114 AF_0954 e476a2ac7dd8c852bf2332e8dbc95f94 280 PIRSF PIRSF006519 25 280 3.5E-94 T 31-10-2018 IPR012061 Glutamate synthase, large subunit domain 3 stand-alone protein AF_1651 d4a59e6c0540b37267de4b672adeb9fb 120 PIRSF PIRSF015873 1 120 2.8E-37 T 31-10-2018 IPR012040 Formylmethanofuran dehydrogenase, subunit D AF_1651 d4a59e6c0540b37267de4b672adeb9fb 120 Pfam PF01568 Molydopterin dinucleotide binding domain 26 83 1.0E-8 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AF_1651 d4a59e6c0540b37267de4b672adeb9fb 120 SUPERFAMILY SSF50692 28 109 1.95E-11 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AF_1651 d4a59e6c0540b37267de4b672adeb9fb 120 Gene3D G3DSA:2.40.40.20 17 107 8.7E-9 T 31-10-2018 AF_1468 b672b52f19e60818d1511cfeeefce440 489 Gene3D G3DSA:2.60.40.10 203 307 1.0E-5 T 31-10-2018 IPR013783 Immunoglobulin-like fold AF_1468 b672b52f19e60818d1511cfeeefce440 489 Pfam PF08626 Transport protein Trs120 or TRAPPC9, TRAPP II complex subunit 35 105 3.6E-5 T 31-10-2018 IPR013935 TRAPP II complex, Trs120 Reactome: R-HSA-204005|Reactome: R-HSA-8876198 AF_1468 b672b52f19e60818d1511cfeeefce440 489 SUPERFAMILY SSF49309 36 108 3.92E-6 T 31-10-2018 IPR036238 Transglutaminase, C-terminal domain superfamily GO:0003810|GO:0018149 AF_0527 8a79fc94f4e6b5ccc21e3a376e6b6412 267 SUPERFAMILY SSF116742 90 178 2.09E-22 T 31-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 AF_0527 8a79fc94f4e6b5ccc21e3a376e6b6412 267 SUPERFAMILY SSF50249 15 102 8.92E-23 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0527 8a79fc94f4e6b5ccc21e3a376e6b6412 267 Gene3D G3DSA:1.10.150.190 90 177 1.2E-24 T 31-10-2018 IPR024054 Translation initiation factor 2, alpha subunit, middle domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 AF_0527 8a79fc94f4e6b5ccc21e3a376e6b6412 267 Gene3D G3DSA:3.30.70.1130 178 264 9.3E-30 T 31-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 AF_0527 8a79fc94f4e6b5ccc21e3a376e6b6412 267 SUPERFAMILY SSF110993 180 262 1.96E-25 T 31-10-2018 IPR024055 Translation initiation factor 2, alpha subunit, C-terminal Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 AF_0527 8a79fc94f4e6b5ccc21e3a376e6b6412 267 Gene3D G3DSA:2.40.50.140 4 89 4.3E-31 T 31-10-2018 AF_0527 8a79fc94f4e6b5ccc21e3a376e6b6412 267 Hamap MF_00231 Translation initiation factor 2 subunit alpha [eif2a]. 8 265 34.914 T 31-10-2018 IPR022964 Translation initiation factor 2, alpha subunit, archaeal AF_0527 8a79fc94f4e6b5ccc21e3a376e6b6412 267 Pfam PF00575 S1 RNA binding domain 14 88 9.7E-17 T 31-10-2018 IPR003029 S1 domain GO:0003676 AF_0527 8a79fc94f4e6b5ccc21e3a376e6b6412 267 SMART SM00316 15 88 1.5E-25 T 31-10-2018 IPR022967 RNA-binding domain, S1 AF_0527 8a79fc94f4e6b5ccc21e3a376e6b6412 267 Pfam PF07541 Eukaryotic translation initiation factor 2 alpha subunit 127 235 8.2E-25 T 31-10-2018 IPR011488 Translation initiation factor 2, alpha subunit GO:0003723|GO:0003743 Reactome: R-HSA-156827|Reactome: R-HSA-381042|Reactome: R-HSA-382556|Reactome: R-HSA-72649|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72731 AF_0029 14017c522de46d861521134e0836ccb6 114 Gene3D G3DSA:3.40.1230.10 1 114 1.0E-33 T 31-10-2018 IPR036748 MTH938-like superfamily AF_0029 14017c522de46d861521134e0836ccb6 114 Pfam PF04430 Protein of unknown function (DUF498/DUF598) 3 109 1.5E-23 T 31-10-2018 IPR007523 NDUFAF3/Mth938 domain-containing protein AF_0029 14017c522de46d861521134e0836ccb6 114 SUPERFAMILY SSF64076 1 114 3.01E-30 T 31-10-2018 IPR036748 MTH938-like superfamily AF_0173 2969885cca9f897a2537ef7d51ba1ce8 159 Pfam PF02613 Nitrate reductase delta subunit 33 114 5.5E-18 T 31-10-2018 IPR020945 DMSO/Nitrate reductase chaperone AF_0173 2969885cca9f897a2537ef7d51ba1ce8 159 Gene3D G3DSA:1.20.120.700 5 151 2.6E-72 T 31-10-2018 AF_0173 2969885cca9f897a2537ef7d51ba1ce8 159 Gene3D G3DSA:1.10.4070.10 59 136 2.6E-72 T 31-10-2018 AF_0173 2969885cca9f897a2537ef7d51ba1ce8 159 SUPERFAMILY SSF89155 3 152 2.22E-36 T 31-10-2018 IPR036411 TorD-like superfamily AF_0526 f0a194a7226bc0defbe581d18e7d0f5e 59 Pfam PF04135 Nucleolar RNA-binding protein, Nop10p family 1 51 4.7E-25 T 31-10-2018 IPR007264 H/ACA ribonucleoprotein complex, subunit Nop10 GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 AF_0526 f0a194a7226bc0defbe581d18e7d0f5e 59 SUPERFAMILY SSF144210 4 54 8.5E-21 T 31-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 AF_0526 f0a194a7226bc0defbe581d18e7d0f5e 59 Hamap MF_00803 Ribosome biogenesis protein Nop10 [nop10]. 3 53 19.071 T 31-10-2018 IPR023532 H/ACA ribonucleoprotein complex subunit Nop10 , archaeal-type GO:0001522|GO:0030515|GO:0042254 AF_0526 f0a194a7226bc0defbe581d18e7d0f5e 59 Gene3D G3DSA:2.20.28.40 1 56 6.6E-26 T 31-10-2018 IPR036756 H/ACA ribonucleoprotein complex, subunit Nop10 superfamily GO:0001522|GO:0030515|GO:0042254 Reactome: R-HSA-6790901 AF_2200 2fb8376edc410b90760440a896a22ac7 179 Pfam PF00293 NUDIX domain 19 110 8.9E-17 T 31-10-2018 IPR000086 NUDIX hydrolase domain GO:0016787 AF_2200 2fb8376edc410b90760440a896a22ac7 179 SUPERFAMILY SSF55811 5 161 2.44E-24 T 31-10-2018 IPR015797 NUDIX hydrolase-like domain superfamily GO:0016787 AF_2200 2fb8376edc410b90760440a896a22ac7 179 Gene3D G3DSA:3.90.79.10 7 163 4.3E-33 T 31-10-2018 AF_2200 2fb8376edc410b90760440a896a22ac7 179 ProSitePatterns PS00893 Nudix box signature. 55 76 - T 31-10-2018 IPR020084 NUDIX hydrolase, conserved site GO:0016787 AF_0738 0c1056a8cb76ce8dab6fe054e145bcf6 93 SUPERFAMILY SSF140371 1 70 7.32E-24 T 31-10-2018 IPR036519 Uncharacterised UPF0058 superfamily AF_0738 0c1056a8cb76ce8dab6fe054e145bcf6 93 Pfam PF01893 Uncharacterised protein family UPF0058 1 71 5.2E-26 T 31-10-2018 IPR002753 Uncharacterised protein family UPF0058 AF_0738 0c1056a8cb76ce8dab6fe054e145bcf6 93 Gene3D G3DSA:1.20.1270.110 1 72 4.7E-23 T 31-10-2018 IPR036519 Uncharacterised UPF0058 superfamily AF_1610 e52efbfc432182d653c60c06b00cb5bb 112 Gene3D G3DSA:3.60.90.10 1 112 1.3E-42 T 31-10-2018 AF_1610 e52efbfc432182d653c60c06b00cb5bb 112 TIGRFAM TIGR03330 SAM_DCase_Bsu: S-adenosylmethionine decarboxylase proenzyme 2 112 2.3E-42 T 31-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 AF_1610 e52efbfc432182d653c60c06b00cb5bb 112 Pfam PF02675 S-adenosylmethionine decarboxylase 6 112 1.6E-35 T 31-10-2018 IPR003826 S-adenosylmethionine decarboxylase family, prokaryotic GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 AF_1610 e52efbfc432182d653c60c06b00cb5bb 112 Hamap MF_00464 S-adenosylmethionine decarboxylase proenzyme [speH]. 1 112 26.753 T 31-10-2018 IPR017716 S-adenosylmethionine decarboxylase proenzyme GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834 AF_1610 e52efbfc432182d653c60c06b00cb5bb 112 SUPERFAMILY SSF56276 2 112 9.42E-37 T 31-10-2018 IPR016067 S-adenosylmethionine decarboxylase, core GO:0004014|GO:0008295 KEGG: 00270+4.1.1.50|KEGG: 00330+4.1.1.50|MetaCyc: PWY-6834|Reactome: R-HSA-351202 AF_1158 1745cbc4de073d7ab1ceab3be6e78b5c 112 TIGRFAM TIGR02926 AhaH: ATP synthase archaeal, H subunit 10 94 2.0E-26 T 31-10-2018 IPR014275 ATPase, A1A0, subunit H AF_0117 031160b59ad49c97d9100b204a998488 320 SUPERFAMILY SSF102114 75 311 1.31E-20 T 31-10-2018 AF_0117 031160b59ad49c97d9100b204a998488 320 Pfam PF13353 4Fe-4S single cluster domain 98 191 1.2E-6 T 31-10-2018 AF_0117 031160b59ad49c97d9100b204a998488 320 Pfam PF04055 Radical SAM superfamily 104 265 2.4E-19 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_0117 031160b59ad49c97d9100b204a998488 320 PIRSF PIRSF004869 11 320 2.6E-81 T 31-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted AF_0117 031160b59ad49c97d9100b204a998488 320 Gene3D G3DSA:3.20.20.70 92 311 2.2E-27 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0771 eafa01a24aa1cfbb1b0a3bdad2022da9 289 Pfam PF01040 UbiA prenyltransferase family 24 257 1.8E-15 T 31-10-2018 IPR000537 UbiA prenyltransferase family GO:0016021|GO:0016765 AF_2208 11012d5427a24963be3ea4998da4f793 243 Gene3D G3DSA:3.40.1190.20 1 239 3.3E-67 T 31-10-2018 IPR029056 Ribokinase-like AF_2208 11012d5427a24963be3ea4998da4f793 243 SUPERFAMILY SSF53613 1 236 2.81E-55 T 31-10-2018 IPR029056 Ribokinase-like AF_2208 11012d5427a24963be3ea4998da4f793 243 Pfam PF08543 Phosphomethylpyrimidine kinase 11 236 2.1E-65 T 31-10-2018 IPR013749 Pyridoxamine kinase/Phosphomethylpyrimidine kinase Reactome: R-HSA-6798695|Reactome: R-HSA-964975 AF_1971 9e6669e0245d699419bc7d44bbc9ade5 140 Gene3D G3DSA:2.60.40.790 3 140 4.2E-38 T 31-10-2018 IPR008978 HSP20-like chaperone AF_1971 9e6669e0245d699419bc7d44bbc9ade5 140 Pfam PF00011 Hsp20/alpha crystallin family 41 139 1.1E-23 T 31-10-2018 IPR002068 Alpha crystallin/Hsp20 domain AF_1971 9e6669e0245d699419bc7d44bbc9ade5 140 SUPERFAMILY SSF49764 7 135 9.21E-37 T 31-10-2018 IPR008978 HSP20-like chaperone AF_1778 c6d8eaa247f9f2739644d641305a8ecd 85 Gene3D G3DSA:3.30.1120.40 1 85 2.1E-34 T 31-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 AF_1778 c6d8eaa247f9f2739644d641305a8ecd 85 SUPERFAMILY SSF160537 3 84 4.19E-30 T 31-10-2018 IPR036751 Stage V sporulation protein G superfamily GO:0030435 AF_1778 c6d8eaa247f9f2739644d641305a8ecd 85 Hamap MF_00819 Putative septation protein SpoVG [spoVG]. 2 85 23.777 T 31-10-2018 IPR007170 Stage V sporulation protein G GO:0030435 AF_1778 c6d8eaa247f9f2739644d641305a8ecd 85 Pfam PF04026 SpoVG 3 83 1.1E-31 T 31-10-2018 IPR007170 Stage V sporulation protein G GO:0030435 AF_1819 0ae2a699af7bb9029bda464c51327a71 231 Pfam PF00005 ABC transporter 21 164 1.6E-35 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_1819 0ae2a699af7bb9029bda464c51327a71 231 ProSitePatterns PS00211 ABC transporters family signature. 137 151 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_1819 0ae2a699af7bb9029bda464c51327a71 231 Gene3D G3DSA:3.40.50.300 1 226 3.5E-68 T 31-10-2018 AF_1819 0ae2a699af7bb9029bda464c51327a71 231 SUPERFAMILY SSF52540 1 218 1.49E-72 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1819 0ae2a699af7bb9029bda464c51327a71 231 SMART SM00382 30 213 7.0E-16 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_2325 e081755420a4b711554c80569d50f305 94 Pfam PF04242 Protein of unknown function (DUF424) 4 94 6.2E-32 T 31-10-2018 IPR007355 Protein of unknown function DUF424 AF_2325 e081755420a4b711554c80569d50f305 94 Gene3D G3DSA:3.30.1860.10 1 94 2.4E-28 T 31-10-2018 AF_0267 e516bb5f0cfa569e0935eb81a29dc81a 597 Pfam PF03417 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase 176 370 5.7E-6 T 31-10-2018 IPR005079 Peptidase C45 AF_0267 e516bb5f0cfa569e0935eb81a29dc81a 597 Gene3D G3DSA:3.60.60.10 153 434 1.1E-25 T 31-10-2018 AF_0725 78519fcf0c0c03e69586fc9624b05241 249 SUPERFAMILY SSF159664 135 249 4.84E-28 T 31-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 AF_0725 78519fcf0c0c03e69586fc9624b05241 249 Pfam PF01890 Cobalamin synthesis G C-terminus 136 248 4.0E-25 T 31-10-2018 IPR002750 CobE/GbiG C-terminal domain GO:0009236 AF_0725 78519fcf0c0c03e69586fc9624b05241 249 Gene3D G3DSA:3.40.50.11220 13 125 6.6E-21 T 31-10-2018 AF_0725 78519fcf0c0c03e69586fc9624b05241 249 Pfam PF11760 Cobalamin synthesis G N-terminal 59 129 1.8E-22 T 31-10-2018 IPR021744 Cobalamin synthesis G, N-terminal KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 AF_0725 78519fcf0c0c03e69586fc9624b05241 249 Gene3D G3DSA:3.30.420.180 127 249 3.1E-27 T 31-10-2018 IPR036518 CobE/GbiG C-terminal domain superfamily GO:0009236 AF_0725 78519fcf0c0c03e69586fc9624b05241 249 SUPERFAMILY SSF159672 26 139 7.85E-25 T 31-10-2018 IPR038029 GbiG N-terminal domain superfamily KEGG: 00860+3.7.1.12|MetaCyc: PWY-7377 AF_1007 b55bfec68a1c71fd67c50d1bacfd341d 284 Pfam PF13175 AAA ATPase domain 1 193 1.5E-18 T 31-10-2018 AF_1007 b55bfec68a1c71fd67c50d1bacfd341d 284 Gene3D G3DSA:3.40.50.300 1 271 1.6E-14 T 31-10-2018 AF_1007 b55bfec68a1c71fd67c50d1bacfd341d 284 SUPERFAMILY SSF52540 1 131 3.49E-13 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0352 4505775d9bc87da2f5d7bc8fc0ebcf3b 228 Gene3D G3DSA:3.40.50.300 1 225 1.4E-6 T 31-10-2018 AF_0629 6017e51a7f837c14cd98d2c10d7ccb16 161 Hamap MF_01032 Methanogen homoaconitase small subunit [hacB]. 1 159 39.647 T 31-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 AF_0629 6017e51a7f837c14cd98d2c10d7ccb16 161 TIGRFAM TIGR02087 LEUD_arch: 3-isopropylmalate dehydratase, small subunit 2 155 2.8E-66 T 31-10-2018 IPR011827 Hydrolyase LeuD/HacB/DmdB GO:0016836 KEGG: 00290+4.2.1.33 AF_0629 6017e51a7f837c14cd98d2c10d7ccb16 161 Gene3D G3DSA:3.20.19.10 1 160 4.1E-59 T 31-10-2018 IPR015928 Aconitase/3-isopropylmalate dehydratase, swivel KEGG: 00290+4.2.1.33 AF_0629 6017e51a7f837c14cd98d2c10d7ccb16 161 Pfam PF00694 Aconitase C-terminal domain 45 103 2.2E-21 T 31-10-2018 IPR000573 Aconitase A/isopropylmalate dehydratase small subunit, swivel domain KEGG: 00290+4.2.1.33 AF_0629 6017e51a7f837c14cd98d2c10d7ccb16 161 SUPERFAMILY SSF52016 2 155 2.35E-50 T 31-10-2018 AF_1263 48f4ca2f25d4c6bdf47536a9fd0c6703 369 Gene3D G3DSA:3.30.70.20 265 353 1.3E-13 T 31-10-2018 AF_1263 48f4ca2f25d4c6bdf47536a9fd0c6703 369 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 321 332 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1263 48f4ca2f25d4c6bdf47536a9fd0c6703 369 SUPERFAMILY SSF54862 278 347 1.16E-17 T 31-10-2018 AF_1263 48f4ca2f25d4c6bdf47536a9fd0c6703 369 Pfam PF14697 4Fe-4S dicluster domain 283 337 4.3E-10 T 31-10-2018 AF_2137 69d8e70da87e839ab30412f8eed98936 283 SUPERFAMILY SSF160240 195 275 1.7E-15 T 31-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AF_2137 69d8e70da87e839ab30412f8eed98936 283 Pfam PF01545 Cation efflux family 4 191 5.6E-33 T 31-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AF_2137 69d8e70da87e839ab30412f8eed98936 283 TIGRFAM TIGR01297 CDF: cation diffusion facilitator family transporter 4 276 6.3E-71 T 31-10-2018 IPR002524 Cation efflux protein GO:0006812|GO:0008324|GO:0016021|GO:0055085 AF_2137 69d8e70da87e839ab30412f8eed98936 283 Gene3D G3DSA:3.30.70.1350 193 276 2.6E-13 T 31-10-2018 IPR036837 Cation efflux protein, cytoplasmic domain superfamily Reactome: R-HSA-435368 AF_2137 69d8e70da87e839ab30412f8eed98936 283 Pfam PF16916 Dimerisation domain of Zinc Transporter 197 274 3.7E-16 T 31-10-2018 IPR027470 Cation efflux protein, cytoplasmic domain AF_2137 69d8e70da87e839ab30412f8eed98936 283 Gene3D G3DSA:1.20.1510.10 4 192 3.4E-34 T 31-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AF_2137 69d8e70da87e839ab30412f8eed98936 283 SUPERFAMILY SSF161111 5 193 5.23E-32 T 31-10-2018 IPR027469 Cation efflux transmembrane domain superfamily AF_1599 3fd8366e668c1601592d00b37bb79f82 248 Hamap MF_00131 Tryptophan synthase alpha chain [trpA]. 1 246 36.061 T 31-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AF_1599 3fd8366e668c1601592d00b37bb79f82 248 TIGRFAM TIGR00262 trpA: tryptophan synthase, alpha subunit 3 244 8.7E-99 T 31-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AF_1599 3fd8366e668c1601592d00b37bb79f82 248 SUPERFAMILY SSF51366 5 240 2.07E-77 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AF_1599 3fd8366e668c1601592d00b37bb79f82 248 Gene3D G3DSA:3.20.20.70 3 247 3.3E-88 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1599 3fd8366e668c1601592d00b37bb79f82 248 ProSitePatterns PS00167 Tryptophan synthase alpha chain signature. 35 48 - T 31-10-2018 IPR018204 Tryptophan synthase, alpha chain, active site GO:0004834 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AF_1599 3fd8366e668c1601592d00b37bb79f82 248 Pfam PF00290 Tryptophan synthase alpha chain 5 243 2.6E-76 T 31-10-2018 IPR002028 Tryptophan synthase, alpha chain GO:0004834|GO:0006568 KEGG: 00260+4.2.1.20|KEGG: 00400+4.2.1.20 AF_1705 7fe2ed6b952cc0d4494432bed1670ab1 299 Pfam PF00665 Integrase core domain 129 245 1.5E-25 T 31-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AF_1705 7fe2ed6b952cc0d4494432bed1670ab1 299 SUPERFAMILY SSF46689 4 109 5.38E-15 T 31-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AF_1705 7fe2ed6b952cc0d4494432bed1670ab1 299 Pfam PF13518 Helix-turn-helix domain 12 58 9.1E-9 T 31-10-2018 AF_1705 7fe2ed6b952cc0d4494432bed1670ab1 299 SUPERFAMILY SSF53098 125 270 1.01E-28 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily AF_1705 7fe2ed6b952cc0d4494432bed1670ab1 299 Gene3D G3DSA:3.30.420.10 124 290 8.5E-23 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AF_1181 5f020c4c7b0b320f9c155a35388cd42c 211 PRINTS PR00449 Transforming protein P21 ras signature 24 45 3.1E-10 T 31-10-2018 AF_1181 5f020c4c7b0b320f9c155a35388cd42c 211 PRINTS PR00449 Transforming protein P21 ras signature 158 171 3.1E-10 T 31-10-2018 AF_1181 5f020c4c7b0b320f9c155a35388cd42c 211 PRINTS PR00449 Transforming protein P21 ras signature 73 95 3.1E-10 T 31-10-2018 AF_1181 5f020c4c7b0b320f9c155a35388cd42c 211 PRINTS PR00449 Transforming protein P21 ras signature 188 210 3.1E-10 T 31-10-2018 AF_1181 5f020c4c7b0b320f9c155a35388cd42c 211 Gene3D G3DSA:3.40.50.300 18 209 1.3E-30 T 31-10-2018 AF_1181 5f020c4c7b0b320f9c155a35388cd42c 211 Pfam PF01926 50S ribosome-binding GTPase 25 168 3.3E-15 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 AF_1181 5f020c4c7b0b320f9c155a35388cd42c 211 SUPERFAMILY SSF52540 19 201 1.01E-29 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1181 5f020c4c7b0b320f9c155a35388cd42c 211 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 23 206 6.3E-19 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AF_0532 d7dd659820ed778527aab8b3602626ef 407 SMART SM00849 14 184 2.0E-20 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_0532 d7dd659820ed778527aab8b3602626ef 407 Pfam PF00753 Metallo-beta-lactamase superfamily 23 162 3.5E-8 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_0532 d7dd659820ed778527aab8b3602626ef 407 SMART SM01027 218 325 2.8E-24 T 31-10-2018 IPR022712 Beta-Casp domain AF_0532 d7dd659820ed778527aab8b3602626ef 407 Gene3D G3DSA:3.40.50.10890 186 349 1.8E-94 T 31-10-2018 AF_0532 d7dd659820ed778527aab8b3602626ef 407 Pfam PF07521 Zn-dependent metallo-hydrolase RNA specificity domain 338 399 1.4E-14 T 31-10-2018 IPR011108 Zn-dependent metallo-hydrolase, RNA specificity domain AF_0532 d7dd659820ed778527aab8b3602626ef 407 Gene3D G3DSA:3.60.15.10 7 380 1.8E-94 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_0532 d7dd659820ed778527aab8b3602626ef 407 Pfam PF10996 Beta-Casp domain 218 323 2.1E-11 T 31-10-2018 IPR022712 Beta-Casp domain AF_0532 d7dd659820ed778527aab8b3602626ef 407 SUPERFAMILY SSF56281 3 406 3.9E-100 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_1431 adf662eab52befdd48e0232a7337ebd0 159 Pfam PF01927 Mut7-C RNAse domain 4 153 1.1E-35 T 31-10-2018 IPR002782 Mut7-C RNAse domain AF_1979 243249af8ed900eeed97980eb970170b 252 SUPERFAMILY SSF81301 37 92 6.13E-8 T 31-10-2018 AF_1979 243249af8ed900eeed97980eb970170b 252 Gene3D G3DSA:3.30.460.10 31 117 3.9E-6 T 31-10-2018 AF_1979 243249af8ed900eeed97980eb970170b 252 Pfam PF01909 Nucleotidyltransferase domain 50 118 3.0E-7 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AF_1979 243249af8ed900eeed97980eb970170b 252 PIRSF PIRSF005928 15 252 4.0E-113 T 31-10-2018 IPR009185 Predicted nucleotidyltransferase AF_1759 99b2672fd1a2ed57046e4286832bab2c 334 Gene3D G3DSA:3.40.1700.10 249 331 1.4E-12 T 31-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily AF_1759 99b2672fd1a2ed57046e4286832bab2c 334 Pfam PF02457 DisA bacterial checkpoint controller nucleotide-binding 197 323 9.6E-21 T 31-10-2018 IPR003390 DNA integrity scanning protein, DisA, N-terminal AF_1759 99b2672fd1a2ed57046e4286832bab2c 334 Hamap MF_00840 Diadenylate cyclase [dacZ]. 60 334 34.074 T 31-10-2018 IPR014499 Diadenylate cyclase, DacZ-type AF_1759 99b2672fd1a2ed57046e4286832bab2c 334 SUPERFAMILY SSF143597 123 328 1.44E-30 T 31-10-2018 IPR036888 DNA integrity scanning protein, DisA, N-terminal domain superfamily AF_1759 99b2672fd1a2ed57046e4286832bab2c 334 PIRSF PIRSF019073 1 334 3.3E-118 T 31-10-2018 IPR014499 Diadenylate cyclase, DacZ-type AF_0186 e6c006ec17abea7f719213f1b7947e58 392 Hamap MF_00331 Cysteine desulfurase IscS [iscS]. 8 392 49.833 T 31-10-2018 IPR010240 Cysteine desulfurase IscS GO:0030170|GO:0031071|GO:0044571 KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250|Reactome: R-HSA-1362409|Reactome: R-HSA-947581 AF_0186 e6c006ec17abea7f719213f1b7947e58 392 PIRSF PIRSF005572 9 387 3.7E-131 T 31-10-2018 IPR016454 Cysteine desulfurase KEGG: 00730+2.8.1.7|MetaCyc: PWY-7250 AF_0186 e6c006ec17abea7f719213f1b7947e58 392 Gene3D G3DSA:3.40.640.10 23 263 2.4E-155 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AF_0186 e6c006ec17abea7f719213f1b7947e58 392 SUPERFAMILY SSF53383 11 382 7.84E-103 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AF_0186 e6c006ec17abea7f719213f1b7947e58 392 Gene3D G3DSA:3.90.1150.10 13 373 2.4E-155 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AF_0186 e6c006ec17abea7f719213f1b7947e58 392 Pfam PF00266 Aminotransferase class-V 13 372 6.3E-80 T 31-10-2018 IPR000192 Aminotransferase class V domain AF_0131 b622e86fd0d5f8b41ff2dc0a223ae4c3 194 SUPERFAMILY SSF55469 8 191 9.95E-46 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AF_0131 b622e86fd0d5f8b41ff2dc0a223ae4c3 194 Gene3D G3DSA:3.40.109.10 6 192 2.3E-51 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AF_0131 b622e86fd0d5f8b41ff2dc0a223ae4c3 194 Pfam PF00881 Nitroreductase family 11 172 9.5E-39 T 31-10-2018 IPR029479 Nitroreductase Reactome: R-HSA-209968 AF_0440 21153a1b9ec2a562d2ef9bd831b7b48a 115 Gene3D G3DSA:3.30.479.10 4 115 1.0E-36 T 31-10-2018 IPR038418 6-pyruvoyl tetrahydropterin synthase/QueD superfamily Reactome: R-HSA-1474151 AF_0440 21153a1b9ec2a562d2ef9bd831b7b48a 115 Pfam PF01242 6-pyruvoyl tetrahydropterin synthase 10 114 5.2E-31 T 31-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 AF_0440 21153a1b9ec2a562d2ef9bd831b7b48a 115 PIRSF PIRSF006113 2 115 7.6E-49 T 31-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 AF_0440 21153a1b9ec2a562d2ef9bd831b7b48a 115 TIGRFAM TIGR03367 queuosine_QueD: queuosine biosynthesis protein QueD 7 92 3.0E-30 T 31-10-2018 IPR007115 6-pyruvoyl tetrahydropterin synthase/QueD family Reactome: R-HSA-1474151 AF_0440 21153a1b9ec2a562d2ef9bd831b7b48a 115 SUPERFAMILY SSF55620 5 114 2.56E-34 T 31-10-2018 AF_0968 bdb4f25ebd93df8d4424c17f38a4eefb 388 SUPERFAMILY SSF53901 15 231 1.86E-15 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0968 bdb4f25ebd93df8d4424c17f38a4eefb 388 Gene3D G3DSA:3.40.47.10 7 387 2.1E-73 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0968 bdb4f25ebd93df8d4424c17f38a4eefb 388 PIRSF PIRSF000429 8 372 1.6E-16 T 31-10-2018 IPR002155 Thiolase GO:0016747 AF_0968 bdb4f25ebd93df8d4424c17f38a4eefb 388 SUPERFAMILY SSF53901 236 372 1.23E-19 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0968 bdb4f25ebd93df8d4424c17f38a4eefb 388 Pfam PF02803 Thiolase, C-terminal domain 261 371 3.4E-6 T 31-10-2018 IPR020617 Thiolase, C-terminal GO:0016747 AF_0036 d629b19ae3d2f3790ce39d9fe79f47b1 216 Pfam PF01135 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) 10 208 3.5E-75 T 31-10-2018 AF_0036 d629b19ae3d2f3790ce39d9fe79f47b1 216 TIGRFAM TIGR00080 pimt: protein-L-isoaspartate O-methyltransferase 5 209 7.1E-79 T 31-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 AF_0036 d629b19ae3d2f3790ce39d9fe79f47b1 216 Gene3D G3DSA:3.40.50.150 1 215 2.2E-82 T 31-10-2018 AF_0036 d629b19ae3d2f3790ce39d9fe79f47b1 216 ProSitePatterns PS01279 Protein-L-isoaspartate(D-aspartate) O-methyltransferase signature. 134 149 - T 31-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 AF_0036 d629b19ae3d2f3790ce39d9fe79f47b1 216 Hamap MF_00090 Protein-L-isoaspartate O-methyltransferase [pcm]. 4 211 42.568 T 31-10-2018 IPR000682 Protein-L-isoaspartate(D-aspartate) O-methyltransferase GO:0004719|GO:0006464 AF_0036 d629b19ae3d2f3790ce39d9fe79f47b1 216 SUPERFAMILY SSF53335 13 182 3.19E-48 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_1069 f997415868dcd31aeba0a154e0cb8a14 491 Pfam PF00474 Sodium:solute symporter family 31 437 7.3E-60 T 31-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AF_1069 f997415868dcd31aeba0a154e0cb8a14 491 Gene3D G3DSA:1.20.1730.10 22 491 3.1E-68 T 31-10-2018 IPR038377 Sodium/glucose symporter superfamily AF_1069 f997415868dcd31aeba0a154e0cb8a14 491 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 150 175 - T 31-10-2018 IPR018212 Sodium/solute symporter, conserved site AF_1069 f997415868dcd31aeba0a154e0cb8a14 491 TIGRFAM TIGR00813 sss: transporter, solute:sodium symporter (SSS) family 31 444 1.0E-55 T 31-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AF_0643 fe52f397baababad3977122a2c9955bf 156 Pfam PF01381 Helix-turn-helix 21 67 3.5E-5 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AF_0643 fe52f397baababad3977122a2c9955bf 156 SUPERFAMILY SSF159800 66 155 3.53E-7 T 31-10-2018 AF_0643 fe52f397baababad3977122a2c9955bf 156 PIRSF PIRSF005978 1 156 1.3E-66 T 31-10-2018 IPR016472 Transcription regulator, MJ0621, predicted AF_0643 fe52f397baababad3977122a2c9955bf 156 SUPERFAMILY SSF47413 14 67 9.76E-6 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AF_1858 1e6f555602e2e7e30c2b012bdae44982 448 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 327 433 1.3E-18 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AF_1858 1e6f555602e2e7e30c2b012bdae44982 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 7 29 3.2E-21 T 31-10-2018 AF_1858 1e6f555602e2e7e30c2b012bdae44982 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 396 416 3.2E-21 T 31-10-2018 AF_1858 1e6f555602e2e7e30c2b012bdae44982 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 232 246 3.2E-21 T 31-10-2018 AF_1858 1e6f555602e2e7e30c2b012bdae44982 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 146 171 3.2E-21 T 31-10-2018 AF_1858 1e6f555602e2e7e30c2b012bdae44982 448 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 273 280 3.2E-21 T 31-10-2018 AF_1858 1e6f555602e2e7e30c2b012bdae44982 448 Gene3D G3DSA:3.50.50.60 109 431 2.6E-117 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1858 1e6f555602e2e7e30c2b012bdae44982 448 Gene3D G3DSA:3.50.50.60 8 338 2.6E-117 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1858 1e6f555602e2e7e30c2b012bdae44982 448 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 6 302 3.0E-65 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AF_1858 1e6f555602e2e7e30c2b012bdae44982 448 SUPERFAMILY SSF55424 321 442 5.84E-24 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AF_1858 1e6f555602e2e7e30c2b012bdae44982 448 SUPERFAMILY SSF51905 4 310 1.01E-46 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1858 1e6f555602e2e7e30c2b012bdae44982 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 258 280 6.6E-27 T 31-10-2018 AF_1858 1e6f555602e2e7e30c2b012bdae44982 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 8 27 6.6E-27 T 31-10-2018 AF_1858 1e6f555602e2e7e30c2b012bdae44982 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 6.6E-27 T 31-10-2018 AF_1858 1e6f555602e2e7e30c2b012bdae44982 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 146 164 6.6E-27 T 31-10-2018 AF_1858 1e6f555602e2e7e30c2b012bdae44982 448 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 231 247 6.6E-27 T 31-10-2018 AF_0422 0d61e165ef65a017061a87efb682e45b 243 TIGRFAM TIGR01469 cobA_cysG_Cterm: uroporphyrinogen-III C-methyltransferase 3 231 1.3E-70 T 31-10-2018 IPR006366 Uroporphyrin-III C-methyltransferase GO:0008168|GO:0019354 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AF_0422 0d61e165ef65a017061a87efb682e45b 243 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 4 210 1.2E-49 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AF_0422 0d61e165ef65a017061a87efb682e45b 243 ProSitePatterns PS00839 Uroporphyrin-III C-methyltransferase signature 1. 8 22 - T 31-10-2018 IPR003043 Uroporphiryn-III C-methyltransferase, conserved site GO:0008168|GO:0055114 KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107|MetaCyc: PWY-5194|MetaCyc: PWY-5196|MetaCyc: PWY-7377 AF_0422 0d61e165ef65a017061a87efb682e45b 243 SUPERFAMILY SSF53790 3 231 4.45E-63 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AF_0422 0d61e165ef65a017061a87efb682e45b 243 Gene3D G3DSA:3.30.950.10 121 240 1.0E-26 T 31-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AF_0422 0d61e165ef65a017061a87efb682e45b 243 Gene3D G3DSA:3.40.1010.10 1 120 4.0E-41 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AF_1485 cc677c7fe23544871d9c54b3aba8f060 403 Hamap MF_00168 Queuine tRNA-ribosyltransferase [tgt]. 3 403 51.813 T 31-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AF_1485 cc677c7fe23544871d9c54b3aba8f060 403 SUPERFAMILY SSF51713 2 401 1.31E-131 T 31-10-2018 IPR036511 Queuine tRNA-ribosyltransferase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AF_1485 cc677c7fe23544871d9c54b3aba8f060 403 TIGRFAM TIGR00449 tgt_general: tRNA-guanine family transglycosylase 5 399 7.2E-170 T 31-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AF_1485 cc677c7fe23544871d9c54b3aba8f060 403 TIGRFAM TIGR00430 Q_tRNA_tgt: tRNA-guanine transglycosylase 5 402 1.0E-177 T 31-10-2018 IPR004803 tRNA-guanine transglycosylase GO:0008479|GO:0101030 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AF_1485 cc677c7fe23544871d9c54b3aba8f060 403 Pfam PF01702 Queuine tRNA-ribosyltransferase 160 400 1.9E-83 T 31-10-2018 IPR002616 tRNA-guanine(15) transglycosylase-like GO:0006400|GO:0016763 MetaCyc: PWY-6700|Reactome: R-HSA-6782315 AF_2059 e8dea8b957a1b83a7371a9caa65fe4d0 196 SUPERFAMILY SSF111278 2 185 1.31E-53 T 31-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 AF_2059 e8dea8b957a1b83a7371a9caa65fe4d0 196 Gene3D G3DSA:3.30.1960.10 1 196 1.6E-75 T 31-10-2018 IPR036602 tRNA wybutosine-synthesizing-like superfamily MetaCyc: PWY-7286|Reactome: R-HSA-6782861 AF_2059 e8dea8b957a1b83a7371a9caa65fe4d0 196 Pfam PF02676 Methyltransferase TYW3 15 185 6.3E-39 T 31-10-2018 IPR003827 tRNA wybutosine-synthesizing protein MetaCyc: PWY-7286|Reactome: R-HSA-6782861 AF_2059 e8dea8b957a1b83a7371a9caa65fe4d0 196 Hamap MF_00266 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase [taw3]. 4 187 28.921 T 31-10-2018 IPR022908 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))-methyltransferase GO:0008175|GO:0030488|GO:0031591 MetaCyc: PWY-7286 AF_1342 1b6e0659557faa3dc1cdeefbe566ee48 505 TIGRFAM TIGR02645 ARCH_P_rylase: putative thymidine phosphorylase 4 492 3.7E-169 T 31-10-2018 IPR013466 Thymidine phosphorylase/AMP phosphorylase GO:0016763 AF_1342 1b6e0659557faa3dc1cdeefbe566ee48 505 Gene3D G3DSA:2.40.40.20 1 84 5.3E-12 T 31-10-2018 AF_1342 1b6e0659557faa3dc1cdeefbe566ee48 505 Pfam PF00591 Glycosyl transferase family, a/b domain 160 243 5.8E-9 T 31-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1342 1b6e0659557faa3dc1cdeefbe566ee48 505 SUPERFAMILY SSF52418 155 402 5.23E-62 T 31-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1342 1b6e0659557faa3dc1cdeefbe566ee48 505 Gene3D G3DSA:3.90.1170.30 411 491 7.2E-26 T 31-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1342 1b6e0659557faa3dc1cdeefbe566ee48 505 Gene3D G3DSA:3.40.1030.10 154 410 2.1E-84 T 31-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1342 1b6e0659557faa3dc1cdeefbe566ee48 505 Pfam PF02885 Glycosyl transferase family, helical bundle domain 90 149 8.4E-11 T 31-10-2018 IPR017459 Glycosyl transferase family 3, N-terminal domain Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1342 1b6e0659557faa3dc1cdeefbe566ee48 505 PIRSF PIRSF000478 85 499 3.5E-112 T 31-10-2018 IPR000053 Thymidine/pyrimidine-nucleoside phosphorylase GO:0004645|GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1342 1b6e0659557faa3dc1cdeefbe566ee48 505 SMART SM00941 422 489 3.7E-21 T 31-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1342 1b6e0659557faa3dc1cdeefbe566ee48 505 Pfam PF07831 Pyrimidine nucleoside phosphorylase C-terminal domain 422 486 2.1E-16 T 31-10-2018 IPR013102 Pyrimidine nucleoside phosphorylase, C-terminal GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1342 1b6e0659557faa3dc1cdeefbe566ee48 505 TIGRFAM TIGR03327 AMP_phos: AMP phosphorylase 3 498 4.9E-196 T 31-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 AF_1342 1b6e0659557faa3dc1cdeefbe566ee48 505 SUPERFAMILY SSF47648 87 154 6.41E-14 T 31-10-2018 IPR036320 Glycosyl transferase family 3, N-terminal domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1342 1b6e0659557faa3dc1cdeefbe566ee48 505 SUPERFAMILY SSF54680 409 496 9.03E-19 T 31-10-2018 IPR036566 Pyrimidine nucleoside phosphorylase-like, C-terminal domain superfamily GO:0006213|GO:0016763 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1342 1b6e0659557faa3dc1cdeefbe566ee48 505 ProSitePatterns PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. 194 209 - T 31-10-2018 IPR017872 Pyrimidine-nucleoside phosphorylase, conserved site GO:0006206 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1342 1b6e0659557faa3dc1cdeefbe566ee48 505 Hamap MF_02132 AMP phosphorylase. 1 501 45.11 T 31-10-2018 IPR017713 AMP phosphorylase GO:0009032|GO:0046125 MetaCyc: PWY-5532 AF_1342 1b6e0659557faa3dc1cdeefbe566ee48 505 Gene3D G3DSA:1.20.970.10 85 152 1.4E-18 T 31-10-2018 AF_0977 987be5f8b35d38afed0c367c01cd285f 391 TIGRFAM TIGR00836 amt: ammonium transporter 5 390 4.7E-140 T 31-10-2018 IPR001905 Ammonium transporter GO:0008519|GO:0016020|GO:0072488 AF_0977 987be5f8b35d38afed0c367c01cd285f 391 Pfam PF00909 Ammonium Transporter Family 7 390 2.5E-135 T 31-10-2018 IPR024041 Ammonium transporter AmtB-like domain GO:0008519|GO:0015696|GO:0016020 AF_0977 987be5f8b35d38afed0c367c01cd285f 391 Gene3D G3DSA:1.10.3430.10 1 391 1.7E-160 T 31-10-2018 IPR029020 Ammonium/urea transporter AF_0977 987be5f8b35d38afed0c367c01cd285f 391 SUPERFAMILY SSF111352 3 371 3.14E-118 T 31-10-2018 AF_1113 25e3bd36fcdc3210ed9a9d65ca0e8e2b 55 Gene3D G3DSA:2.20.25.660 1 53 4.8E-20 T 31-10-2018 IPR038582 S27a-like superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 AF_1113 25e3bd36fcdc3210ed9a9d65ca0e8e2b 55 SUPERFAMILY SSF57829 8 55 3.3E-20 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AF_1113 25e3bd36fcdc3210ed9a9d65ca0e8e2b 55 Pfam PF01599 Ribosomal protein S27a 9 50 1.2E-20 T 31-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 AF_1113 25e3bd36fcdc3210ed9a9d65ca0e8e2b 55 SMART SM01402 8 50 2.9E-22 T 31-10-2018 IPR002906 Ribosomal protein S27a GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 AF_1113 25e3bd36fcdc3210ed9a9d65ca0e8e2b 55 Hamap MF_00777 30S ribosomal protein S27ae [rps27ae]. 8 53 18.424 T 31-10-2018 IPR022845 Ribosomal protein S27ae AF_1805 4b398481cf57713900b80bf4b98c31dd 181 Gene3D G3DSA:3.30.1370.10 83 180 2.9E-31 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AF_1805 4b398481cf57713900b80bf4b98c31dd 181 SUPERFAMILY SSF54791 100 174 6.14E-20 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AF_1805 4b398481cf57713900b80bf4b98c31dd 181 SMART SM00322 84 155 7.2E-11 T 31-10-2018 IPR004087 K Homology domain GO:0003676 AF_1805 4b398481cf57713900b80bf4b98c31dd 181 SMART SM00322 3 68 4.1E-8 T 31-10-2018 IPR004087 K Homology domain GO:0003676 AF_1805 4b398481cf57713900b80bf4b98c31dd 181 TIGRFAM TIGR03665 arCOG04150: arCOG04150 universal archaeal KH domain protein 9 177 1.9E-63 T 31-10-2018 IPR019964 KH domain protein, archaea AF_1805 4b398481cf57713900b80bf4b98c31dd 181 SUPERFAMILY SSF54791 6 75 4.03E-12 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AF_1805 4b398481cf57713900b80bf4b98c31dd 181 Gene3D G3DSA:3.30.1370.10 4 81 1.7E-23 T 31-10-2018 IPR036612 K Homology domain, type 1 superfamily GO:0003723 AF_1805 4b398481cf57713900b80bf4b98c31dd 181 Pfam PF00013 KH domain 7 49 4.0E-8 T 31-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 AF_1805 4b398481cf57713900b80bf4b98c31dd 181 Pfam PF00013 KH domain 104 151 1.5E-8 T 31-10-2018 IPR004088 K Homology domain, type 1 GO:0003723 AF_0010 32206b5d61d8117f9268b15a1e8c0cbb 597 Gene3D G3DSA:3.10.20.30 1 98 2.7E-22 T 31-10-2018 IPR012675 Beta-grasp domain superfamily AF_0010 32206b5d61d8117f9268b15a1e8c0cbb 597 Pfam PF14574 Domain of unknown function (DUF4445) 190 594 8.3E-142 T 31-10-2018 IPR027980 Protein of unknown function DUF4445 AF_0010 32206b5d61d8117f9268b15a1e8c0cbb 597 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 10 84 9.5E-13 T 31-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AF_0010 32206b5d61d8117f9268b15a1e8c0cbb 597 Gene3D G3DSA:3.30.420.480 188 362 2.6E-55 T 31-10-2018 AF_0010 32206b5d61d8117f9268b15a1e8c0cbb 597 Gene3D G3DSA:2.40.50.570 110 187 4.7E-11 T 31-10-2018 AF_0010 32206b5d61d8117f9268b15a1e8c0cbb 597 SUPERFAMILY SSF54292 2 92 1.66E-19 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AF_1070 4ac32c4f9484f3b3de44eed49179ecf1 413 SUPERFAMILY SSF56801 44 352 2.49E-44 T 31-10-2018 AF_1070 4ac32c4f9484f3b3de44eed49179ecf1 413 Pfam PF00501 AMP-binding enzyme 14 286 6.7E-13 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_1070 4ac32c4f9484f3b3de44eed49179ecf1 413 Gene3D G3DSA:3.40.50.12780 6 327 9.7E-117 T 31-10-2018 AF_1070 4ac32c4f9484f3b3de44eed49179ecf1 413 Gene3D G3DSA:3.30.300.30 328 412 1.3E-14 T 31-10-2018 AF_1070 4ac32c4f9484f3b3de44eed49179ecf1 413 Pfam PF14535 AMP-binding enzyme C-terminal domain 336 411 3.3E-7 T 31-10-2018 IPR028154 AMP-dependent ligase, C-terminal AF_0243 498c4331038e20d98f8f5332fa78dce2 529 Pfam PF04055 Radical SAM superfamily 165 357 4.8E-13 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_0243 498c4331038e20d98f8f5332fa78dce2 529 Gene3D G3DSA:3.80.30.20 162 410 1.8E-18 T 31-10-2018 IPR023404 Radical SAM, alpha/beta horseshoe AF_0243 498c4331038e20d98f8f5332fa78dce2 529 SUPERFAMILY SSF102114 161 389 1.96E-18 T 31-10-2018 AF_0243 498c4331038e20d98f8f5332fa78dce2 529 SMART SM00729 161 400 7.5E-23 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AF_0456 0341da7ec389b39f94d481ec400c8655 151 Pfam PF09719 Putative redox-active protein (C_GCAxxG_C_C) 20 142 7.5E-18 T 31-10-2018 IPR010181 CGCAxxGCC motif AF_0456 0341da7ec389b39f94d481ec400c8655 151 TIGRFAM TIGR01909 C_GCAxxG_C_C: C_GCAxxG_C_C family protein 19 146 3.0E-47 T 31-10-2018 IPR010181 CGCAxxGCC motif AF_0456 0341da7ec389b39f94d481ec400c8655 151 SUPERFAMILY SSF48695 3 92 1.51E-15 T 31-10-2018 IPR036280 Multiheme cytochrome superfamily AF_1091 9fc119e38b49fd853b550cf1bf03a5c8 139 Gene3D G3DSA:3.40.50.1010 2 138 4.2E-12 T 31-10-2018 AF_1091 9fc119e38b49fd853b550cf1bf03a5c8 139 SMART SM00670 1 130 1.5E-30 T 31-10-2018 IPR002716 PIN domain AF_1091 9fc119e38b49fd853b550cf1bf03a5c8 139 SUPERFAMILY SSF88723 2 133 2.8E-19 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_1091 9fc119e38b49fd853b550cf1bf03a5c8 139 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 138 9.751 T 31-10-2018 IPR022907 VapC family GO:0004540 AF_1091 9fc119e38b49fd853b550cf1bf03a5c8 139 Pfam PF01850 PIN domain 3 133 2.5E-25 T 31-10-2018 IPR002716 PIN domain AF_0961 123be332e076ebcd0bb01c53f8f68910 241 Pfam PF02653 Branched-chain amino acid transport system / permease component 4 238 1.6E-13 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AF_1547 1c0d3bda198654a291782d6cc2ad7485 47 Pfam PF03477 ATP cone domain 3 42 6.0E-7 T 31-10-2018 IPR005144 ATP-cone domain Reactome: R-HSA-499943 AF_2305 db0ba77e90062bbf4c141238d47b48f5 56 SUPERFAMILY SSF81593 2 50 2.51E-7 T 31-10-2018 AF_2305 db0ba77e90062bbf4c141238d47b48f5 56 Pfam PF05168 HEPN domain 2 48 1.4E-5 T 31-10-2018 IPR007842 HEPN domain AF_2305 db0ba77e90062bbf4c141238d47b48f5 56 Gene3D G3DSA:1.20.120.330 1 52 5.1E-7 T 31-10-2018 AF_1604 13fc03c655628d0663022f8499e0b837 546 Hamap MF_00211 Anthranilate phosphoribosyltransferase [trpD]. 226 542 33.205 T 31-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 AF_1604 13fc03c655628d0663022f8499e0b837 546 Pfam PF00218 Indole-3-glycerol phosphate synthase 5 220 2.6E-38 T 31-10-2018 IPR013798 Indole-3-glycerol phosphate synthase GO:0004425 KEGG: 00400+4.1.1.48 AF_1604 13fc03c655628d0663022f8499e0b837 546 SUPERFAMILY SSF51366 4 222 9.42E-46 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AF_1604 13fc03c655628d0663022f8499e0b837 546 Gene3D G3DSA:1.20.970.10 235 397 7.8E-91 T 31-10-2018 AF_1604 13fc03c655628d0663022f8499e0b837 546 Gene3D G3DSA:3.20.20.70 2 227 1.4E-50 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1604 13fc03c655628d0663022f8499e0b837 546 Pfam PF00591 Glycosyl transferase family, a/b domain 289 531 1.8E-73 T 31-10-2018 IPR000312 Glycosyl transferase, family 3 GO:0016757 Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1604 13fc03c655628d0663022f8499e0b837 546 SUPERFAMILY SSF52418 289 539 6.54E-69 T 31-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1604 13fc03c655628d0663022f8499e0b837 546 Gene3D G3DSA:3.40.1030.10 288 522 7.8E-91 T 31-10-2018 IPR035902 Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain superfamily Reactome: R-HSA-73614|Reactome: R-HSA-73621 AF_1604 13fc03c655628d0663022f8499e0b837 546 TIGRFAM TIGR01245 trpD: anthranilate phosphoribosyltransferase 234 540 8.9E-97 T 31-10-2018 IPR005940 Anthranilate phosphoribosyl transferase GO:0000162|GO:0004048 KEGG: 00400+2.4.2.18 AF_1473 2ba24a318d7e8556f8f43f29b0f18068 133 SMART SM00448 2 117 2.6E-30 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_1473 2ba24a318d7e8556f8f43f29b0f18068 133 Pfam PF00072 Response regulator receiver domain 4 115 5.1E-24 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_1473 2ba24a318d7e8556f8f43f29b0f18068 133 SUPERFAMILY SSF52172 3 119 2.99E-32 T 31-10-2018 IPR011006 CheY-like superfamily AF_1473 2ba24a318d7e8556f8f43f29b0f18068 133 Gene3D G3DSA:3.40.50.2300 2 132 2.7E-37 T 31-10-2018 AF_0902 4fd6185b0e0634bdbe17968fef3b3e3b 270 Pfam PF04055 Radical SAM superfamily 24 177 2.3E-11 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_0902 4fd6185b0e0634bdbe17968fef3b3e3b 270 SUPERFAMILY SSF102114 12 173 1.31E-5 T 31-10-2018 AF_0902 4fd6185b0e0634bdbe17968fef3b3e3b 270 Gene3D G3DSA:3.80.30.30 51 181 1.5E-8 T 31-10-2018 AF_0169 b158a0d2d70a81dc23ec84b081c8b9a7 153 Pfam PF08984 Domain of unknown function (DUF1858) 84 141 1.5E-16 T 31-10-2018 IPR015077 Domain of unknown function DUF1858 AF_0169 b158a0d2d70a81dc23ec84b081c8b9a7 153 SUPERFAMILY SSF140683 81 148 3.53E-17 T 31-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily AF_0169 b158a0d2d70a81dc23ec84b081c8b9a7 153 Gene3D G3DSA:1.10.3910.10 79 148 3.0E-17 T 31-10-2018 IPR038062 ScdA-like, N-terminal domain superfamily AF_0626 b4c731ee7ec7038a7dbf2b8f6f12a5e0 218 TIGRFAM TIGR00266 TIGR00266: TIGR00266 family protein 1 217 1.6E-102 T 31-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 AF_0626 b4c731ee7ec7038a7dbf2b8f6f12a5e0 218 SUPERFAMILY SSF51219 1 217 1.54E-66 T 31-10-2018 IPR016031 Tryptophan RNA-binding attenuator protein-like domain superfamily AF_0626 b4c731ee7ec7038a7dbf2b8f6f12a5e0 218 Pfam PF01987 Mitochondrial biogenesis AIM24 4 202 9.6E-59 T 31-10-2018 IPR002838 Mitochondrial biogenesis protein AIM24 AF_0626 b4c731ee7ec7038a7dbf2b8f6f12a5e0 218 Gene3D G3DSA:3.60.160.10 1 218 6.2E-77 T 31-10-2018 IPR036983 Mitochondrial biogenesis AIM24 superfamily AF_0042 57bc0bea356b5a22333ab011759bb3f6 254 Pfam PF01061 ABC-2 type transporter 13 215 5.2E-29 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AF_0042 57bc0bea356b5a22333ab011759bb3f6 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 32 53 7.3E-7 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AF_0042 57bc0bea356b5a22333ab011759bb3f6 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 173 192 7.3E-7 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AF_0042 57bc0bea356b5a22333ab011759bb3f6 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 136 160 7.3E-7 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AF_0042 57bc0bea356b5a22333ab011759bb3f6 254 PRINTS PR00164 ABC-2 type transport system membrane protein signature 193 212 7.3E-7 T 31-10-2018 IPR000412 ABC-2 transporter GO:0016021|GO:0043190|GO:0055085 AF_1998 475981803c33718d11f3ed4920d3a8b7 354 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 47 58 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1998 475981803c33718d11f3ed4920d3a8b7 354 Pfam PF13183 4Fe-4S dicluster domain 4 61 9.3E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1998 475981803c33718d11f3ed4920d3a8b7 354 SUPERFAMILY SSF46548 4 81 5.23E-14 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_1998 475981803c33718d11f3ed4920d3a8b7 354 Pfam PF02754 Cysteine-rich domain 240 325 6.1E-18 T 31-10-2018 IPR004017 Cysteine-rich domain AF_1998 475981803c33718d11f3ed4920d3a8b7 354 Pfam PF02754 Cysteine-rich domain 123 207 6.5E-17 T 31-10-2018 IPR004017 Cysteine-rich domain AF_1998 475981803c33718d11f3ed4920d3a8b7 354 Gene3D G3DSA:1.10.1060.10 1 76 3.7E-6 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_1768 2f4d982ae273561e58a6e0a882928387 354 SUPERFAMILY SSF161098 113 341 3.07E-8 T 31-10-2018 IPR035906 MetI-like superfamily AF_1768 2f4d982ae273561e58a6e0a882928387 354 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 135 354 1.3E-47 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AF_1768 2f4d982ae273561e58a6e0a882928387 354 Gene3D G3DSA:1.10.3720.10 108 348 1.0E-15 T 31-10-2018 IPR035906 MetI-like superfamily AF_1670 374bd7d04709e9cdcc634b078436f19e 643 Pfam PF00890 FAD binding domain 24 263 8.2E-16 T 31-10-2018 IPR003953 FAD-dependent oxidoreductase 2, FAD binding domain Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_1670 374bd7d04709e9cdcc634b078436f19e 643 PIRSF PIRSF000171 13 642 6.3E-250 T 31-10-2018 AF_1670 374bd7d04709e9cdcc634b078436f19e 643 Pfam PF02910 Fumarate reductase flavoprotein C-term 520 632 3.8E-8 T 31-10-2018 IPR015939 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_1670 374bd7d04709e9cdcc634b078436f19e 643 SUPERFAMILY SSF51905 3 498 2.16E-80 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1670 374bd7d04709e9cdcc634b078436f19e 643 Gene3D G3DSA:3.50.50.90 22 638 1.7E-294 T 31-10-2018 AF_1670 374bd7d04709e9cdcc634b078436f19e 643 SUPERFAMILY SSF46977 507 641 5.89E-46 T 31-10-2018 IPR037099 Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily GO:0016491|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_1670 374bd7d04709e9cdcc634b078436f19e 643 Gene3D G3DSA:3.90.700.10 282 411 1.7E-294 T 31-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_1670 374bd7d04709e9cdcc634b078436f19e 643 TIGRFAM TIGR02061 aprA: adenylylsulfate reductase, alpha subunit 24 639 0.0 T 31-10-2018 IPR011803 Adenylylsulphate reductase, alpha subunit KEGG: 00920+1.8.99.2|MetaCyc: PWY-5278|MetaCyc: PWY-5279 AF_1670 374bd7d04709e9cdcc634b078436f19e 643 SUPERFAMILY SSF56425 257 400 4.92E-64 T 31-10-2018 IPR027477 Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily Reactome: R-HSA-611105|Reactome: R-HSA-71403 AF_0637 0d5ff88c9be231bfd4dae89dff6ed1dc 152 PIRSF PIRSF008455 1 152 6.2E-70 T 31-10-2018 IPR014451 Uncharacterised conserved protein UCP008455 AF_0637 0d5ff88c9be231bfd4dae89dff6ed1dc 152 Pfam PF08905 Domain of unknown function (DUF1850) 44 127 2.8E-17 T 31-10-2018 IPR015001 Protein of unknown function DUF1850 AF_1937 32e4690c27ee05f0174c81838cdc6d9a 252 Gene3D G3DSA:3.40.50.300 3 226 5.3E-46 T 31-10-2018 AF_1937 32e4690c27ee05f0174c81838cdc6d9a 252 SUPERFAMILY SSF52540 4 226 4.84E-41 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1937 32e4690c27ee05f0174c81838cdc6d9a 252 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 5 206 7.0E-19 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AF_2275 39a576af7951fb9860a24c3fcbcabf23 411 SUPERFAMILY SSF47203 264 405 1.37E-48 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AF_2275 39a576af7951fb9860a24c3fcbcabf23 411 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 12 119 7.8E-10 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AF_2275 39a576af7951fb9860a24c3fcbcabf23 411 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 127 218 3.5E-23 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AF_2275 39a576af7951fb9860a24c3fcbcabf23 411 SUPERFAMILY SSF56645 7 226 5.1E-50 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AF_2275 39a576af7951fb9860a24c3fcbcabf23 411 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 265 402 7.5E-42 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AF_2275 39a576af7951fb9860a24c3fcbcabf23 411 Gene3D G3DSA:2.40.110.10 127 232 3.6E-31 T 31-10-2018 AF_2275 39a576af7951fb9860a24c3fcbcabf23 411 Gene3D G3DSA:1.10.540.10 3 123 9.2E-13 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AF_2275 39a576af7951fb9860a24c3fcbcabf23 411 Gene3D G3DSA:1.20.140.10 259 408 8.7E-48 T 31-10-2018 AF_2275 39a576af7951fb9860a24c3fcbcabf23 411 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 361 380 - T 31-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AF_1066 7d1ae5116942a056af9da8b154650519 332 TIGRFAM TIGR03555 F420_mer: 5,10-methylenetetrahydromethanopterin reductase 3 329 2.1E-177 T 31-10-2018 IPR019946 5,10-methylenetetrahydromethanopterin reductase GO:0018537|GO:0055114 KEGG: 00680+1.5.98.2|MetaCyc: PWY-7784 AF_1066 7d1ae5116942a056af9da8b154650519 332 Pfam PF00296 Luciferase-like monooxygenase 15 305 3.1E-69 T 31-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AF_1066 7d1ae5116942a056af9da8b154650519 332 Hamap MF_01091 5,10-methylenetetrahydromethanopterin reductase [mer]. 1 332 177.2 T 31-10-2018 IPR019946 5,10-methylenetetrahydromethanopterin reductase GO:0018537|GO:0055114 KEGG: 00680+1.5.98.2|MetaCyc: PWY-7784 AF_1066 7d1ae5116942a056af9da8b154650519 332 Gene3D G3DSA:3.20.20.30 1 330 1.5E-116 T 31-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AF_1066 7d1ae5116942a056af9da8b154650519 332 SUPERFAMILY SSF51679 1 331 5.23E-73 T 31-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AF_1725 eb14c77a748997568d99ee7edee9bbc3 313 SUPERFAMILY SSF50249 199 310 5.6E-32 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_1725 eb14c77a748997568d99ee7edee9bbc3 313 SUPERFAMILY SSF56091 7 196 6.91E-39 T 31-10-2018 AF_1725 eb14c77a748997568d99ee7edee9bbc3 313 Gene3D G3DSA:2.40.50.140 198 312 9.4E-38 T 31-10-2018 AF_1725 eb14c77a748997568d99ee7edee9bbc3 313 Pfam PF01068 ATP dependent DNA ligase domain 10 196 2.3E-40 T 31-10-2018 IPR012310 DNA ligase, ATP-dependent, central GO:0003910|GO:0005524|GO:0006281|GO:0006310 AF_1725 eb14c77a748997568d99ee7edee9bbc3 313 Gene3D G3DSA:3.30.1490.70 17 194 1.4E-42 T 31-10-2018 AF_1725 eb14c77a748997568d99ee7edee9bbc3 313 TIGRFAM TIGR02779 NHEJ_ligase_lig: DNA ligase D, ligase domain 10 311 1.6E-97 T 31-10-2018 IPR014146 DNA ligase D, ligase domain AF_1725 eb14c77a748997568d99ee7edee9bbc3 313 Pfam PF04679 ATP dependent DNA ligase C terminal region 215 305 2.2E-26 T 31-10-2018 IPR012309 DNA ligase, ATP-dependent, C-terminal GO:0003910|GO:0006281|GO:0006310 AF_1725 eb14c77a748997568d99ee7edee9bbc3 313 Gene3D G3DSA:3.30.470.30 32 152 1.4E-42 T 31-10-2018 AF_1359 51d138c0c0377a51f10c166b17a2557d 251 ProSitePatterns PS00211 ABC transporters family signature. 148 162 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_1359 51d138c0c0377a51f10c166b17a2557d 251 Pfam PF00005 ABC transporter 21 176 3.9E-33 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_1359 51d138c0c0377a51f10c166b17a2557d 251 SUPERFAMILY SSF52540 4 238 6.51E-63 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1359 51d138c0c0377a51f10c166b17a2557d 251 SMART SM00382 29 226 7.5E-14 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1359 51d138c0c0377a51f10c166b17a2557d 251 TIGRFAM TIGR00972 3a0107s01c2: phosphate ABC transporter, ATP-binding protein 5 251 1.9E-128 T 31-10-2018 IPR005670 Phosphate transport system permease protein 1 GO:0005315|GO:0016020|GO:0035435 AF_1359 51d138c0c0377a51f10c166b17a2557d 251 Gene3D G3DSA:3.40.50.300 2 248 4.3E-68 T 31-10-2018 AF_0556 532753d265238ca60f97fbc6c0846865 73 ProSitePatterns PS01148 Uncharacterized protein family UPF0033 signature. 4 28 - T 31-10-2018 IPR001455 TusA-like domain AF_0556 532753d265238ca60f97fbc6c0846865 73 Gene3D G3DSA:3.30.110.40 1 73 5.5E-29 T 31-10-2018 IPR036868 TusA-like domain superfamily AF_0556 532753d265238ca60f97fbc6c0846865 73 Pfam PF01206 Sulfurtransferase TusA 3 71 1.7E-25 T 31-10-2018 IPR001455 TusA-like domain AF_0556 532753d265238ca60f97fbc6c0846865 73 SUPERFAMILY SSF64307 1 71 8.5E-24 T 31-10-2018 IPR036868 TusA-like domain superfamily AF_2203 76c30cc1a086506734ae2f689868a684 119 Pfam PF03551 Transcriptional regulator PadR-like family 24 95 2.4E-24 T 31-10-2018 IPR005149 Transcription regulator PadR, N-terminal AF_2203 76c30cc1a086506734ae2f689868a684 119 SUPERFAMILY SSF46785 13 110 8.91E-25 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_2203 76c30cc1a086506734ae2f689868a684 119 Gene3D G3DSA:1.10.10.10 8 118 1.1E-29 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_2140 18fb18235d177d827f98f5c1f37590ae 161 SUPERFAMILY SSF46689 25 136 9.86E-23 T 31-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AF_2140 18fb18235d177d827f98f5c1f37590ae 161 Pfam PF13565 Homeodomain-like domain 60 132 1.4E-17 T 31-10-2018 AF_1351 18fb18235d177d827f98f5c1f37590ae 161 SUPERFAMILY SSF46689 25 136 9.86E-23 T 31-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AF_1351 18fb18235d177d827f98f5c1f37590ae 161 Pfam PF13565 Homeodomain-like domain 60 132 1.4E-17 T 31-10-2018 AF_0720 50233763f238c4fc19571616d4c84477 214 TIGRFAM TIGR00290 MJ0570_dom: MJ0570-related uncharacterized domain 7 211 5.2E-84 T 31-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 AF_0720 50233763f238c4fc19571616d4c84477 214 Gene3D G3DSA:3.40.50.620 3 137 1.3E-31 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_0720 50233763f238c4fc19571616d4c84477 214 Pfam PF01902 Diphthamide synthase 6 213 5.7E-94 T 31-10-2018 IPR002761 Diphthamide synthase domain MetaCyc: PWY-6482|MetaCyc: PWY-7546|Reactome: R-HSA-5358493 AF_0720 50233763f238c4fc19571616d4c84477 214 SUPERFAMILY SSF52402 4 211 1.49E-56 T 31-10-2018 AF_0720 50233763f238c4fc19571616d4c84477 214 Gene3D G3DSA:3.90.1490.10 140 208 7.9E-10 T 31-10-2018 AF_1583 9a94c592605c486b4fba651f95b15db8 390 Pfam PF04055 Radical SAM superfamily 32 220 6.3E-15 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_1583 9a94c592605c486b4fba651f95b15db8 390 SUPERFAMILY SSF102114 26 260 4.71E-12 T 31-10-2018 AF_1583 9a94c592605c486b4fba651f95b15db8 390 SMART SM00729 27 262 2.3E-4 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AF_2005 92438adfca5a2c3e71a3ad20895499a4 200 Pfam PF12804 MobA-like NTP transferase domain 4 153 5.2E-24 T 31-10-2018 IPR025877 MobA-like NTP transferase AF_2005 92438adfca5a2c3e71a3ad20895499a4 200 SUPERFAMILY SSF53448 2 185 5.63E-21 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_2005 92438adfca5a2c3e71a3ad20895499a4 200 Gene3D G3DSA:3.90.550.10 1 200 5.7E-57 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_2062 f74d1eb276c24c5c4c39461154059a3b 340 Gene3D G3DSA:3.40.50.300 134 340 4.4E-77 T 31-10-2018 AF_2062 f74d1eb276c24c5c4c39461154059a3b 340 SUPERFAMILY SSF52540 141 339 6.0E-50 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2062 f74d1eb276c24c5c4c39461154059a3b 340 SMART SM00382 144 339 9.5E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_2062 f74d1eb276c24c5c4c39461154059a3b 340 SMART SM00962 145 340 2.4E-106 T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AF_2062 f74d1eb276c24c5c4c39461154059a3b 340 SUPERFAMILY SSF47364 56 132 1.05E-11 T 31-10-2018 IPR036225 SRP/SRP receptor, N-terminal Reactome: R-HSA-1799339 AF_2062 f74d1eb276c24c5c4c39461154059a3b 340 Pfam PF00448 SRP54-type protein, GTPase domain 145 339 9.5E-76 T 31-10-2018 IPR000897 Signal recognition particle, SRP54 subunit, GTPase domain GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AF_2062 f74d1eb276c24c5c4c39461154059a3b 340 SMART SM00963 42 121 3.2E-8 T 31-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AF_2062 f74d1eb276c24c5c4c39461154059a3b 340 Hamap MF_00920 Signal recognition particle receptor FtsY [ftsY]. 64 340 60.217 T 31-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 AF_2062 f74d1eb276c24c5c4c39461154059a3b 340 Pfam PF02881 SRP54-type protein, helical bundle domain 51 117 2.8E-10 T 31-10-2018 IPR013822 Signal recognition particle, SRP54 subunit, helical bundle GO:0005525|GO:0006614 Reactome: R-HSA-1799339 AF_2062 f74d1eb276c24c5c4c39461154059a3b 340 Gene3D G3DSA:1.20.120.140 4 128 1.4E-14 T 31-10-2018 AF_2062 f74d1eb276c24c5c4c39461154059a3b 340 TIGRFAM TIGR00064 ftsY: signal recognition particle-docking protein FtsY 65 339 1.3E-109 T 31-10-2018 IPR004390 Signal-recognition particle receptor FtsY GO:0006614 AF_0230 14995fa257a3cd39b6e7a4cb88c21a42 260 SUPERFAMILY SSF51569 6 243 7.69E-67 T 31-10-2018 AF_0230 14995fa257a3cd39b6e7a4cb88c21a42 260 TIGRFAM TIGR01949 AroFGH_arch: predicted phospho-2-dehydro-3-deoxyheptonate aldolase 5 252 1.6E-122 T 31-10-2018 IPR010210 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase GO:0009073|GO:0016836 KEGG: 00400+2.2.1.10|MetaCyc: PWY-6160 AF_0230 14995fa257a3cd39b6e7a4cb88c21a42 260 PIRSF PIRSF038992 3 256 1.5E-75 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AF_0230 14995fa257a3cd39b6e7a4cb88c21a42 260 Gene3D G3DSA:3.20.20.70 2 256 1.6E-82 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0230 14995fa257a3cd39b6e7a4cb88c21a42 260 Hamap MF_00960 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [aroA']. 4 255 55.98 T 31-10-2018 IPR010210 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase GO:0009073|GO:0016836 KEGG: 00400+2.2.1.10|MetaCyc: PWY-6160 AF_0230 14995fa257a3cd39b6e7a4cb88c21a42 260 SMART SM01133 20 227 8.6E-47 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AF_0230 14995fa257a3cd39b6e7a4cb88c21a42 260 Pfam PF01791 DeoC/LacD family aldolase 20 226 1.1E-44 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AF_1896 fd0d902967877b5102df8b071962ff06 201 Pfam PF03358 NADPH-dependent FMN reductase 1 137 1.8E-34 T 31-10-2018 IPR005025 NADPH-dependent FMN reductase-like GO:0016491 AF_1896 fd0d902967877b5102df8b071962ff06 201 Gene3D G3DSA:3.40.50.360 2 198 3.9E-39 T 31-10-2018 IPR029039 Flavoprotein-like superfamily AF_1896 fd0d902967877b5102df8b071962ff06 201 SUPERFAMILY SSF52218 1 194 1.8E-42 T 31-10-2018 IPR029039 Flavoprotein-like superfamily AF_0480 2ba6c20c7f7b7810b265d96833c267ad 186 SMART SM01007 10 178 1.0E-33 T 31-10-2018 IPR001303 Class II aldolase/adducin N-terminal AF_0480 2ba6c20c7f7b7810b265d96833c267ad 186 Gene3D G3DSA:3.40.225.10 6 185 2.3E-42 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily AF_0480 2ba6c20c7f7b7810b265d96833c267ad 186 SUPERFAMILY SSF53639 9 185 2.75E-38 T 31-10-2018 IPR036409 Class II aldolase/adducin N-terminal domain superfamily AF_0480 2ba6c20c7f7b7810b265d96833c267ad 186 Pfam PF00596 Class II Aldolase and Adducin N-terminal domain 11 177 2.1E-31 T 31-10-2018 IPR001303 Class II aldolase/adducin N-terminal AF_0798 868b1512f41589f1367d6c4d17d1d7c6 338 PIRSF PIRSF004762 3 337 2.5E-119 T 31-10-2018 AF_0798 868b1512f41589f1367d6c4d17d1d7c6 338 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 34 337 2.1E-145 T 31-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 AF_0798 868b1512f41589f1367d6c4d17d1d7c6 338 Hamap MF_01612 FO synthase subunit 2 [cofH]. 1 338 52.476 T 31-10-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77 AF_0798 868b1512f41589f1367d6c4d17d1d7c6 338 Gene3D G3DSA:3.20.20.70 3 334 3.4E-63 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0798 868b1512f41589f1367d6c4d17d1d7c6 338 SMART SM00729 38 255 9.9E-8 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AF_0798 868b1512f41589f1367d6c4d17d1d7c6 338 Pfam PF04055 Radical SAM superfamily 42 210 4.8E-21 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_0798 868b1512f41589f1367d6c4d17d1d7c6 338 TIGRFAM TIGR03551 F420_cofH: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofH subunit 11 336 4.0E-159 T 31-10-2018 IPR019940 CofH family GO:0016765 KEGG: 00680+2.5.1.77 AF_0798 868b1512f41589f1367d6c4d17d1d7c6 338 SUPERFAMILY SSF102114 14 329 2.62E-55 T 31-10-2018 AF_0112 383fe4a49e062fda18914ef7c8d2d2e9 253 Hamap MF_01121 NAD-dependent protein deacylase [cobB]. 16 248 60.923 T 31-10-2018 IPR027546 Sirtuin, class III GO:0036054|GO:0036055|GO:0070403 Reactome: R-HSA-2151201 AF_0112 383fe4a49e062fda18914ef7c8d2d2e9 253 Gene3D G3DSA:3.40.50.1220 14 242 1.3E-89 T 31-10-2018 AF_0112 383fe4a49e062fda18914ef7c8d2d2e9 253 Hamap MF_01968 NAD-dependent protein deacetylase [cobB]. 7 243 58.332 T 31-10-2018 IPR028628 Sirtuin, class U GO:0034979|GO:0051287 AF_0112 383fe4a49e062fda18914ef7c8d2d2e9 253 Gene3D G3DSA:3.30.1600.10 32 168 1.3E-89 T 31-10-2018 IPR026591 Sirtuin, catalytic core small domain superfamily AF_0112 383fe4a49e062fda18914ef7c8d2d2e9 253 SUPERFAMILY SSF52467 2 246 1.05E-90 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AF_0112 383fe4a49e062fda18914ef7c8d2d2e9 253 Pfam PF02146 Sir2 family 23 198 1.6E-59 T 31-10-2018 IPR003000 Sirtuin family GO:0070403 AF_0483 e94fe39847efac6febbf17696fcc4283 71 SUPERFAMILY SSF57783 3 48 1.79E-6 T 31-10-2018 AF_0901 87a8e863b65645dc2251867a0455713e 169 Gene3D G3DSA:3.90.950.10 1 169 9.7E-52 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AF_0901 87a8e863b65645dc2251867a0455713e 169 SUPERFAMILY SSF52972 1 168 1.92E-46 T 31-10-2018 IPR029001 Inosine triphosphate pyrophosphatase-like AF_0901 87a8e863b65645dc2251867a0455713e 169 Hamap MF_00648 Non-canonical purine NTP phosphatase. 1 168 29.594 T 31-10-2018 IPR002786 Non-canonical purine NTP phosphatase AF_0901 87a8e863b65645dc2251867a0455713e 169 TIGRFAM TIGR00258 TIGR00258: inosine/xanthosine triphosphatase 1 169 5.3E-81 T 31-10-2018 IPR002786 Non-canonical purine NTP phosphatase AF_0901 87a8e863b65645dc2251867a0455713e 169 Pfam PF01931 Protein of unknown function DUF84 2 163 5.0E-50 T 31-10-2018 IPR026533 Non-canonical purine NTP phosphatase/PRRC1 AF_2072 bfde495a06fe8da8a54ac83bc9ce7eb7 78 Hamap MF_00634 UPF0235 protein YggU [yggU]. 4 78 12.67 T 31-10-2018 IPR003746 Protein of unknown function DUF167 AF_2072 bfde495a06fe8da8a54ac83bc9ce7eb7 78 Pfam PF02594 Uncharacterised ACR, YggU family COG1872 7 74 6.9E-19 T 31-10-2018 IPR003746 Protein of unknown function DUF167 AF_2072 bfde495a06fe8da8a54ac83bc9ce7eb7 78 Gene3D G3DSA:3.30.1200.10 1 77 9.2E-23 T 31-10-2018 IPR036591 YggU-like superfamily AF_2072 bfde495a06fe8da8a54ac83bc9ce7eb7 78 SMART SM01152 4 77 4.8E-19 T 31-10-2018 IPR003746 Protein of unknown function DUF167 AF_2072 bfde495a06fe8da8a54ac83bc9ce7eb7 78 SUPERFAMILY SSF69786 2 73 1.02E-16 T 31-10-2018 IPR036591 YggU-like superfamily AF_2072 bfde495a06fe8da8a54ac83bc9ce7eb7 78 TIGRFAM TIGR00251 TIGR00251: TIGR00251 family protein 1 76 7.7E-35 T 31-10-2018 IPR005228 Conserved hypothetical protein CHP00251 AF_0280 dbb438ebc5104340cdf45fb53e921575 71 SUPERFAMILY SSF50249 11 71 4.51E-17 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0280 dbb438ebc5104340cdf45fb53e921575 71 Gene3D G3DSA:2.40.50.140 5 71 7.3E-25 T 31-10-2018 AF_0280 dbb438ebc5104340cdf45fb53e921575 71 Pfam PF01938 TRAM domain 14 70 2.5E-16 T 31-10-2018 IPR002792 TRAM domain AF_0314 07082af6f1c6b8f197c0549fab815031 64 SUPERFAMILY SSF141694 1 57 2.07E-17 T 31-10-2018 AF_0314 07082af6f1c6b8f197c0549fab815031 64 Pfam PF01954 Protein of unknown function DUF104 1 55 4.4E-22 T 31-10-2018 IPR008203 Uncharacterised protein family UPF0165 AF_0314 07082af6f1c6b8f197c0549fab815031 64 Gene3D G3DSA:4.10.1150.10 1 63 1.4E-19 T 31-10-2018 IPR024069 AF2212-like domain superfamily AF_1817 d3a3fff3f2c0d2dafd3a5152f61f7bb1 169 Pfam PF00440 Bacterial regulatory proteins, tetR family 8 54 1.1E-15 T 31-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AF_1817 d3a3fff3f2c0d2dafd3a5152f61f7bb1 169 SUPERFAMILY SSF46689 7 67 4.05E-15 T 31-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AF_1817 d3a3fff3f2c0d2dafd3a5152f61f7bb1 169 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 29 52 3.3E-7 T 31-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AF_1817 d3a3fff3f2c0d2dafd3a5152f61f7bb1 169 PRINTS PR00455 TetR bacterial regulatory protein HTH signature 8 21 3.3E-7 T 31-10-2018 IPR001647 DNA-binding HTH domain, TetR-type GO:0003677 AF_1817 d3a3fff3f2c0d2dafd3a5152f61f7bb1 169 Gene3D G3DSA:1.10.357.10 1 169 3.4E-66 T 31-10-2018 AF_0009 46971fb868ccb8427dacfd232cc10125 293 ProDom PD009948 METHYLTRANSFERASE SUBUNIT H TRANSFERASE M TETRAHYDROMETHANOPTERIN S-METHYLTRANSFERASE N5-METHYLTETRAHYDROMETHANOPTERIN--COENZYME METHANOGENESIS ONE-CARBON 75 277 6.0E-109 T 31-10-2018 IPR023467 Tetrahydromethanopterin S-methyltransferase, subunit H/Methyltransferase Mtx, subunit H GO:0006730|GO:0008168 AF_0009 46971fb868ccb8427dacfd232cc10125 293 PIRSF PIRSF004960 4 293 1.2E-121 T 31-10-2018 IPR023467 Tetrahydromethanopterin S-methyltransferase, subunit H/Methyltransferase Mtx, subunit H GO:0006730|GO:0008168 AF_0009 46971fb868ccb8427dacfd232cc10125 293 PIRSF PIRSF500206 4 293 6.1E-128 T 31-10-2018 AF_0009 46971fb868ccb8427dacfd232cc10125 293 Gene3D G3DSA:3.20.20.20 73 266 5.0E-9 T 31-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AF_0009 46971fb868ccb8427dacfd232cc10125 293 SUPERFAMILY SSF51717 25 260 2.16E-15 T 31-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AF_0009 46971fb868ccb8427dacfd232cc10125 293 Pfam PF02007 Tetrahydromethanopterin S-methyltransferase MtrH subunit 9 293 1.1E-132 T 31-10-2018 IPR023467 Tetrahydromethanopterin S-methyltransferase, subunit H/Methyltransferase Mtx, subunit H GO:0006730|GO:0008168 AF_1136 fa9b4e3f2eb0d2b0ce920bed78d0ab86 294 SUPERFAMILY SSF52540 4 222 1.28E-63 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1136 fa9b4e3f2eb0d2b0ce920bed78d0ab86 294 Gene3D G3DSA:3.40.50.300 1 229 8.6E-68 T 31-10-2018 AF_1136 fa9b4e3f2eb0d2b0ce920bed78d0ab86 294 Pfam PF00005 ABC transporter 19 159 2.8E-30 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_1136 fa9b4e3f2eb0d2b0ce920bed78d0ab86 294 SMART SM00382 28 229 6.9E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0468 944cbaf13b3968273dfb72696241916e 267 SUPERFAMILY SSF52518 14 215 8.76E-75 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold AF_0468 944cbaf13b3968273dfb72696241916e 267 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 50 197 2.5E-40 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AF_0468 944cbaf13b3968273dfb72696241916e 267 Gene3D G3DSA:3.40.50.970 24 204 8.1E-33 T 31-10-2018 AF_1430 35f79223f3f491e25f9280051814a676 49 Pfam PF01020 Ribosomal L40e family 14 44 2.2E-4 T 31-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 AF_1430 35f79223f3f491e25f9280051814a676 49 SMART SM01377 1 46 1.5E-8 T 31-10-2018 IPR001975 Ribosomal protein L40e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 AF_1430 35f79223f3f491e25f9280051814a676 49 Hamap MF_00788 50S ribosomal protein L40e [rpl40e]. 2 47 19.399 T 31-10-2018 IPR023657 Ribosomal protein L40e, archaeal GO:0003735|GO:0005840|GO:0006412 AF_1430 35f79223f3f491e25f9280051814a676 49 SUPERFAMILY SSF57829 2 47 8.61E-16 T 31-10-2018 IPR011332 Zinc-binding ribosomal protein GO:0006412 AF_1430 35f79223f3f491e25f9280051814a676 49 Gene3D G3DSA:2.20.28.70 1 48 2.0E-17 T 31-10-2018 IPR038587 Ribosomal protein L40e superfamily Reactome: R-HSA-110312|Reactome: R-HSA-110314|Reactome: R-HSA-110320|Reactome: R-HSA-1169091|Reactome: R-HSA-1169408|Reactome: R-HSA-1234176|Reactome: R-HSA-1236382|Reactome: R-HSA-1236974|Reactome: R-HSA-1253288|Reactome: R-HSA-1295596|Reactome: R-HSA-1358803|Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-162588|Reactome: R-HSA-168638|Reactome: R-HSA-168927|Reactome: R-HSA-168928|Reactome: R-HSA-174048|Reactome: R-HSA-174084|Reactome: R-HSA-174113|Reactome: R-HSA-174154|Reactome: R-HSA-174178|Reactome: R-HSA-174184|Reactome: R-HSA-174490|Reactome: R-HSA-175474|Reactome: R-HSA-179409|Reactome: R-HSA-1799339|Reactome: R-HSA-180534|Reactome: R-HSA-180585|Reactome: R-HSA-182971|Reactome: R-HSA-187577|Reactome: R-HSA-192823|Reactome: R-HSA-195253|Reactome: R-HSA-201681|Reactome: R-HSA-202424|Reactome: R-HSA-205043|Reactome: R-HSA-209543|Reactome: R-HSA-209560|Reactome: R-HSA-211733|Reactome: R-HSA-2122947|Reactome: R-HSA-2122948|Reactome: R-HSA-2173788|Reactome: R-HSA-2173791|Reactome: R-HSA-2173795|Reactome: R-HSA-2173796|Reactome: R-HSA-2408557|Reactome: R-HSA-2467813|Reactome: R-HSA-2559580|Reactome: R-HSA-2559582|Reactome: R-HSA-2559585|Reactome: R-HSA-2565942|Reactome: R-HSA-2644606|Reactome: R-HSA-2672351|Reactome: R-HSA-2691232|Reactome: R-HSA-2871837|Reactome: R-HSA-2894862|Reactome: R-HSA-2979096|Reactome: R-HSA-3134975|Reactome: R-HSA-3322077|Reactome: R-HSA-349425|Reactome: R-HSA-3769402|Reactome: R-HSA-3785653|Reactome: R-HSA-382556|Reactome: R-HSA-400253|Reactome: R-HSA-445989|Reactome: R-HSA-450302|Reactome: R-HSA-450321|Reactome: R-HSA-450408|Reactome: R-HSA-4608870|Reactome: R-HSA-4641257|Reactome: R-HSA-4641258|Reactome: R-HSA-4641263|Reactome: R-HSA-5205685|Reactome: R-HSA-532668|Reactome: R-HSA-5357905|Reactome: R-HSA-5357956|Reactome: R-HSA-5358346|Reactome: R-HSA-5362768|Reactome: R-HSA-5607761|Reactome: R-HSA-5607764|Reactome: R-HSA-5610780|Reactome: R-HSA-5610783|Reactome: R-HSA-5610785|Reactome: R-HSA-5632684|Reactome: R-HSA-5654726|Reactome: R-HSA-5654727|Reactome: R-HSA-5654732|Reactome: R-HSA-5654733|Reactome: R-HSA-5655862|Reactome: R-HSA-5656121|Reactome: R-HSA-5656169|Reactome: R-HSA-5658442|Reactome: R-HSA-5668541|Reactome: R-HSA-5675221|Reactome: R-HSA-5675482|Reactome: R-HSA-5676590|Reactome: R-HSA-5678895|Reactome: R-HSA-5684264|Reactome: R-HSA-5685942|Reactome: R-HSA-5687128|Reactome: R-HSA-5689603|Reactome: R-HSA-5689877|Reactome: R-HSA-5689880|Reactome: R-HSA-5689896|Reactome: R-HSA-5689901|Reactome: R-HSA-5693565|Reactome: R-HSA-5693607|Reactome: R-HSA-5696394|Reactome: R-HSA-5696395|Reactome: R-HSA-5696397|Reactome: R-HSA-5696400|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6783310|Reactome: R-HSA-6791226|Reactome: R-HSA-6804756|Reactome: R-HSA-6804757|Reactome: R-HSA-6804760|Reactome: R-HSA-6807004|Reactome: R-HSA-68827|Reactome: R-HSA-68949|Reactome: R-HSA-69017|Reactome: R-HSA-69229|Reactome: R-HSA-69231|Reactome: R-HSA-69481|Reactome: R-HSA-69541|Reactome: R-HSA-69601|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8849469|Reactome: R-HSA-8852276|Reactome: R-HSA-8854050|Reactome: R-HSA-8856825|Reactome: R-HSA-8856828|Reactome: R-HSA-8863795|Reactome: R-HSA-8866652|Reactome: R-HSA-8866654|Reactome: R-HSA-8875360|Reactome: R-HSA-8876493|Reactome: R-HSA-8939236|Reactome: R-HSA-8939902|Reactome: R-HSA-8941858|Reactome: R-HSA-8948747|Reactome: R-HSA-8948751|Reactome: R-HSA-8951664|Reactome: R-HSA-901032|Reactome: R-HSA-9010553|Reactome: R-HSA-9013507|Reactome: R-HSA-9013973|Reactome: R-HSA-9014325|Reactome: R-HSA-9020702|Reactome: R-HSA-9033241|Reactome: R-HSA-912631|Reactome: R-HSA-917729|Reactome: R-HSA-917937|Reactome: R-HSA-936440|Reactome: R-HSA-936964|Reactome: R-HSA-937039|Reactome: R-HSA-937041|Reactome: R-HSA-937042|Reactome: R-HSA-937072|Reactome: R-HSA-9604323|Reactome: R-HSA-975110|Reactome: R-HSA-975144|Reactome: R-HSA-975163|Reactome: R-HSA-975956|Reactome: R-HSA-975957|Reactome: R-HSA-977225|Reactome: R-HSA-983168 AF_0171 8e0ae5c456b29c9e640127a9fbc00ff7 201 Gene3D G3DSA:3.90.420.10 12 134 1.6E-25 T 31-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 AF_0171 8e0ae5c456b29c9e640127a9fbc00ff7 201 SUPERFAMILY SSF56524 4 133 2.75E-36 T 31-10-2018 IPR036374 Oxidoreductase, molybdopterin-binding domain superfamily GO:0042128 Reactome: R-HSA-1614517 AF_0171 8e0ae5c456b29c9e640127a9fbc00ff7 201 Pfam PF00174 Oxidoreductase molybdopterin binding domain 23 133 4.6E-20 T 31-10-2018 IPR000572 Oxidoreductase, molybdopterin-binding domain GO:0042128 Reactome: R-HSA-1614517 AF_1711 eab1f1568aceb6ac20d7a92ef5bffb7d 147 Gene3D G3DSA:3.40.50.1010 1 122 6.5E-9 T 31-10-2018 AF_1711 eab1f1568aceb6ac20d7a92ef5bffb7d 147 Pfam PF01850 PIN domain 2 119 1.3E-18 T 31-10-2018 IPR002716 PIN domain AF_1711 eab1f1568aceb6ac20d7a92ef5bffb7d 147 SUPERFAMILY SSF88723 1 127 1.09E-16 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_0383 ab1b6b802a03dca3a312a4fb5c2a4923 100 Pfam PF01986 Domain of unknown function DUF123 8 89 6.6E-23 T 31-10-2018 IPR002837 Protein of unknown function DUF123 AF_0383 ab1b6b802a03dca3a312a4fb5c2a4923 100 SMART SM00465 1 91 2.7E-13 T 31-10-2018 IPR000305 GIY-YIG endonuclease AF_0207 c4f7f26ebf253451b93e7c11e7974754 86 Gene3D G3DSA:3.30.1360.10 1 86 5.6E-25 T 31-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_0207 c4f7f26ebf253451b93e7c11e7974754 86 SUPERFAMILY SSF55257 1 85 1.57E-25 T 31-10-2018 IPR036603 RNA polymerase, RBP11-like subunit GO:0006351|GO:0046983 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_0207 c4f7f26ebf253451b93e7c11e7974754 86 Pfam PF13656 RNA polymerase Rpb3/Rpb11 dimerisation domain 13 84 1.6E-21 T 31-10-2018 IPR009025 DNA-directed RNA polymerase, RBP11-like dimerisation domain GO:0006351|GO:0046983 AF_0207 c4f7f26ebf253451b93e7c11e7974754 86 ProSitePatterns PS01154 RNA polymerases L / 13 to 16 Kd subunits signature. 17 48 - T 31-10-2018 IPR008193 DNA-directed RNA polymerase Rpb11, 13-16kDa subunit, conserved site GO:0003677|GO:0003899|GO:0006351 AF_0207 c4f7f26ebf253451b93e7c11e7974754 86 Hamap MF_00261 DNA-directed RNA polymerase subunit L [rpoL]. 1 86 20.151 T 31-10-2018 IPR022905 DNA-directed RNA polymerase subunit L (Rpo11) GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_0293 15743ec3a64df38eb9428f10a08d4c0e 151 SUPERFAMILY SSF88723 4 145 5.61E-15 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_0293 15743ec3a64df38eb9428f10a08d4c0e 151 Gene3D G3DSA:3.40.50.1010 4 147 4.2E-10 T 31-10-2018 AF_0293 15743ec3a64df38eb9428f10a08d4c0e 151 Pfam PF01850 PIN domain 4 142 3.3E-23 T 31-10-2018 IPR002716 PIN domain AF_1184 0c5bf1d890b935da6fe7ccf0778699dc 456 SMART SM00091 6 73 1.1E-9 T 31-10-2018 IPR000014 PAS domain AF_1184 0c5bf1d890b935da6fe7ccf0778699dc 456 SMART SM00091 129 194 7.8E-10 T 31-10-2018 IPR000014 PAS domain AF_1184 0c5bf1d890b935da6fe7ccf0778699dc 456 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 7 124 5.3E-17 T 31-10-2018 IPR000014 PAS domain AF_1184 0c5bf1d890b935da6fe7ccf0778699dc 456 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 125 246 7.7E-30 T 31-10-2018 IPR000014 PAS domain AF_1184 0c5bf1d890b935da6fe7ccf0778699dc 456 SMART SM00387 350 453 1.1E-25 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_1184 0c5bf1d890b935da6fe7ccf0778699dc 456 SUPERFAMILY SSF55874 318 452 2.23E-26 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_1184 0c5bf1d890b935da6fe7ccf0778699dc 456 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 353 451 4.8E-17 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_1184 0c5bf1d890b935da6fe7ccf0778699dc 456 Pfam PF13426 PAS domain 146 241 2.8E-12 T 31-10-2018 IPR000014 PAS domain AF_1184 0c5bf1d890b935da6fe7ccf0778699dc 456 Pfam PF00989 PAS fold 8 114 1.4E-10 T 31-10-2018 IPR013767 PAS fold GO:0006355 AF_1184 0c5bf1d890b935da6fe7ccf0778699dc 456 SUPERFAMILY SSF55785 18 126 1.59E-19 T 31-10-2018 IPR035965 PAS domain superfamily AF_1184 0c5bf1d890b935da6fe7ccf0778699dc 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 403 413 1.5E-11 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1184 0c5bf1d890b935da6fe7ccf0778699dc 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 413 431 1.5E-11 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1184 0c5bf1d890b935da6fe7ccf0778699dc 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 385 399 1.5E-11 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1184 0c5bf1d890b935da6fe7ccf0778699dc 456 PRINTS PR00344 Bacterial sensor protein C-terminal signature 437 450 1.5E-11 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1184 0c5bf1d890b935da6fe7ccf0778699dc 456 SUPERFAMILY SSF55785 114 240 2.9E-26 T 31-10-2018 IPR035965 PAS domain superfamily AF_1184 0c5bf1d890b935da6fe7ccf0778699dc 456 SMART SM00388 255 318 0.008 T 31-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AF_1184 0c5bf1d890b935da6fe7ccf0778699dc 456 Gene3D G3DSA:3.30.450.20 115 240 3.6E-26 T 31-10-2018 AF_1184 0c5bf1d890b935da6fe7ccf0778699dc 456 Gene3D G3DSA:3.30.450.20 4 114 3.7E-17 T 31-10-2018 AF_1184 0c5bf1d890b935da6fe7ccf0778699dc 456 Gene3D G3DSA:3.30.565.10 316 450 1.0E-31 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_1184 0c5bf1d890b935da6fe7ccf0778699dc 456 Gene3D G3DSA:1.10.287.130 263 315 1.0E-31 T 31-10-2018 AF_0032 27d245728582e5b25bfdbe5d8e354e86 234 Pfam PF01966 HD domain 71 161 7.6E-13 T 31-10-2018 IPR006674 HD domain AF_0032 27d245728582e5b25bfdbe5d8e354e86 234 TIGRFAM TIGR00277 HDIG: HDIG domain 67 142 7.8E-21 T 31-10-2018 IPR006675 HDIG domain AF_0032 27d245728582e5b25bfdbe5d8e354e86 234 Gene3D G3DSA:1.10.3210.10 55 196 1.4E-12 T 31-10-2018 AF_0032 27d245728582e5b25bfdbe5d8e354e86 234 SMART SM00471 66 174 2.7E-5 T 31-10-2018 IPR003607 HD/PDEase domain AF_0032 27d245728582e5b25bfdbe5d8e354e86 234 SUPERFAMILY SSF109604 59 203 2.86E-17 T 31-10-2018 AF_1632 048fed9dde319d8c8799a88c2ef633a4 334 Pfam PF01925 Sulfite exporter TauE/SafE 53 319 7.7E-36 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AF_0406 823f4fea964798656cf6baa872c77bac 216 SUPERFAMILY SSF56399 35 206 2.53E-51 T 31-10-2018 AF_0406 823f4fea964798656cf6baa872c77bac 216 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 34 195 1.1E-29 T 31-10-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 AF_0406 823f4fea964798656cf6baa872c77bac 216 Gene3D G3DSA:1.10.10.970 33 103 2.1E-24 T 31-10-2018 AF_0406 823f4fea964798656cf6baa872c77bac 216 Gene3D G3DSA:3.20.170.30 123 212 9.8E-23 T 31-10-2018 AF_0406 823f4fea964798656cf6baa872c77bac 216 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 32 204 34.468 T 31-10-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 AF_0790 f0d2b994a4835d6f839c2d5e27fc9d4f 184 Gene3D G3DSA:3.40.50.150 1 184 3.0E-38 T 31-10-2018 AF_0790 f0d2b994a4835d6f839c2d5e27fc9d4f 184 SUPERFAMILY SSF53335 2 173 1.45E-26 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_0790 f0d2b994a4835d6f839c2d5e27fc9d4f 184 Pfam PF08241 Methyltransferase domain 38 114 6.7E-12 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AF_1965 d9ef565c6008d354ffe2b76628d9f705 136 Pfam PF01870 Archaeal holliday junction resolvase (hjc) 7 98 5.7E-33 T 31-10-2018 IPR002732 Holliday junction resolvase Hjc AF_1965 d9ef565c6008d354ffe2b76628d9f705 136 ProDom PD015874 RESOLVASE HOLLIDAY JUNCTION ARCHAEAL HOLLIDAY-JUNCTION TYPE MJ0497 ORF-C21_024 PF1503 NEQ424 9 97 5.0E-46 T 31-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal AF_1965 d9ef565c6008d354ffe2b76628d9f705 136 SUPERFAMILY SSF52980 5 131 1.61E-27 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AF_1965 d9ef565c6008d354ffe2b76628d9f705 136 Gene3D G3DSA:3.40.1350.10 1 136 8.1E-56 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 AF_1965 d9ef565c6008d354ffe2b76628d9f705 136 Hamap MF_01490 Holliday junction resolvase Hjc [hjc]. 1 132 39.26 T 31-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal AF_1965 d9ef565c6008d354ffe2b76628d9f705 136 PIRSF PIRSF004985 1 135 1.1E-45 T 31-10-2018 IPR014428 Holliday junction resolvase Hjc, archaeal AF_2336 146b863c8ce700a972aab82d70088935 247 SUPERFAMILY SSF53474 20 245 4.29E-46 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_2336 146b863c8ce700a972aab82d70088935 247 Gene3D G3DSA:3.40.50.1820 2 247 3.9E-67 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_2336 146b863c8ce700a972aab82d70088935 247 PRINTS PR00111 Alpha/beta hydrolase fold signature 98 111 2.2E-8 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_2336 146b863c8ce700a972aab82d70088935 247 PRINTS PR00111 Alpha/beta hydrolase fold signature 84 97 2.2E-8 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_2336 146b863c8ce700a972aab82d70088935 247 PRINTS PR00111 Alpha/beta hydrolase fold signature 190 204 2.2E-8 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_2336 146b863c8ce700a972aab82d70088935 247 Pfam PF12697 Alpha/beta hydrolase family 26 239 1.8E-21 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_0041 f85f34a86f376fb0a0c696bed24587fa 237 SUPERFAMILY SSF52540 37 234 9.47E-49 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0041 f85f34a86f376fb0a0c696bed24587fa 237 Pfam PF00005 ABC transporter 41 172 4.2E-22 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0041 f85f34a86f376fb0a0c696bed24587fa 237 Gene3D G3DSA:3.40.50.300 21 236 4.8E-48 T 31-10-2018 AF_0041 f85f34a86f376fb0a0c696bed24587fa 237 SMART SM00382 50 230 2.5E-14 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0390 2cd6707b69d837005d56d89cce821b42 355 TIGRFAM TIGR00423 TIGR00423: radical SAM domain protein, CofH subfamily 49 352 2.9E-140 T 31-10-2018 IPR020050 FO synthase, subunit 2 GO:0016765 KEGG: 00680+2.5.1.77 AF_0390 2cd6707b69d837005d56d89cce821b42 355 PIRSF PIRSF004762 7 355 5.0E-110 T 31-10-2018 AF_0390 2cd6707b69d837005d56d89cce821b42 355 Gene3D G3DSA:3.20.20.70 2 346 4.5E-65 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0390 2cd6707b69d837005d56d89cce821b42 355 TIGRFAM TIGR03699 menaquin_MqnC: dehypoxanthine futalosine cyclase 15 352 4.0E-153 T 31-10-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 AF_0390 2cd6707b69d837005d56d89cce821b42 355 SUPERFAMILY SSF102114 16 317 2.88E-55 T 31-10-2018 AF_0390 2cd6707b69d837005d56d89cce821b42 355 Pfam PF04055 Radical SAM superfamily 57 225 2.0E-20 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_0390 2cd6707b69d837005d56d89cce821b42 355 Hamap MF_00992 Cyclic dehypoxanthine futalosine synthase [mqnC]. 14 355 52.258 T 31-10-2018 IPR022431 Cyclic dehypoxanthine futalosine synthase GO:0009234 KEGG: 00130+1.21.98.1|MetaCyc: PWY-7371|MetaCyc: PWY-7374 AF_1606 38495a304252f64f36b8979d43b7b1a6 242 SUPERFAMILY SSF161098 3 240 3.83E-50 T 31-10-2018 IPR035906 MetI-like superfamily AF_1606 38495a304252f64f36b8979d43b7b1a6 242 Gene3D G3DSA:1.10.3720.10 1 242 7.9E-43 T 31-10-2018 IPR035906 MetI-like superfamily AF_1606 38495a304252f64f36b8979d43b7b1a6 242 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 64 234 5.6E-12 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AF_1475 fba2d3be863d42700d16ffada4e220d0 153 Gene3D G3DSA:1.20.1260.100 1 153 4.6E-47 T 31-10-2018 IPR038330 TspO/MBR-related superfamily AF_1475 fba2d3be863d42700d16ffada4e220d0 153 PIRSF PIRSF005859 1 153 2.4E-45 T 31-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 AF_1475 fba2d3be863d42700d16ffada4e220d0 153 Pfam PF03073 TspO/MBR family 9 149 9.3E-42 T 31-10-2018 IPR004307 TspO/MBR-related protein GO:0016021 AF_0403 a74486d7eaa47755b689b9d617f90517 231 Gene3D G3DSA:3.20.20.390 1 231 1.0E-95 T 31-10-2018 IPR038597 GGGP/HepGP synthase superfamily AF_0403 a74486d7eaa47755b689b9d617f90517 231 TIGRFAM TIGR04146 GGGPS_Afulg: phosphoglycerol geranylgeranyltransferase 3 230 2.9E-108 T 31-10-2018 IPR026438 Geranylgeranylglyceryl phosphate synthase, archaea GO:0002094|GO:0046474 KEGG: 00564+2.5.1.41|MetaCyc: PWY-6349 AF_0403 a74486d7eaa47755b689b9d617f90517 231 Pfam PF01884 PcrB family 1 229 3.6E-103 T 31-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 AF_0403 a74486d7eaa47755b689b9d617f90517 231 TIGRFAM TIGR01768 GGGP-family: geranylgeranylglyceryl phosphate synthase family protein 7 230 7.7E-95 T 31-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 AF_0403 a74486d7eaa47755b689b9d617f90517 231 Hamap MF_00112 Geranylgeranylglyceryl phosphate synthase [pcrB]. 2 229 27.298 T 31-10-2018 IPR008205 Geranylgeranylglyceryl phosphate synthase/Heptaprenylglyceryl phosphate synthase GO:0016765 AF_0403 a74486d7eaa47755b689b9d617f90517 231 SUPERFAMILY SSF51395 1 224 2.93E-53 T 31-10-2018 AF_1141 73f96aad74373abcf900db82bdf7bff9 387 SUPERFAMILY SSF56645 3 245 1.27E-82 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AF_1141 73f96aad74373abcf900db82bdf7bff9 387 SUPERFAMILY SSF47203 232 385 7.78E-54 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AF_1141 73f96aad74373abcf900db82bdf7bff9 387 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 8 120 2.8E-33 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AF_1141 73f96aad74373abcf900db82bdf7bff9 387 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 222 1.0E-27 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AF_1141 73f96aad74373abcf900db82bdf7bff9 387 Gene3D G3DSA:1.10.540.10 1 120 3.4E-39 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AF_1141 73f96aad74373abcf900db82bdf7bff9 387 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 234 384 2.0E-48 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AF_1141 73f96aad74373abcf900db82bdf7bff9 387 PIRSF PIRSF016578 6 373 3.1E-21 T 31-10-2018 AF_1141 73f96aad74373abcf900db82bdf7bff9 387 Gene3D G3DSA:2.40.110.10 124 238 4.5E-44 T 31-10-2018 AF_1141 73f96aad74373abcf900db82bdf7bff9 387 Gene3D G3DSA:1.20.140.10 239 386 1.2E-51 T 31-10-2018 AF_0074 f20837c734c2f6d3e36df143bf62b8a3 299 SUPERFAMILY SSF55681 82 253 6.09E-44 T 31-10-2018 AF_0074 f20837c734c2f6d3e36df143bf62b8a3 299 Hamap MF_00978 Bifunctional ligase/repressor BirA [birA]. 8 299 30.619 T 31-10-2018 IPR030855 Bifunctional ligase/repressor BirA GO:0004077|GO:0006355 KEGG: 00780+6.3.4.15 AF_0074 f20837c734c2f6d3e36df143bf62b8a3 299 Gene3D G3DSA:1.10.10.10 4 61 8.7E-13 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0074 f20837c734c2f6d3e36df143bf62b8a3 299 Gene3D G3DSA:3.30.930.10 70 253 6.3E-47 T 31-10-2018 AF_0074 f20837c734c2f6d3e36df143bf62b8a3 299 TIGRFAM TIGR00122 birA_repr_reg: biotin operon repressor 8 76 1.7E-30 T 31-10-2018 IPR004409 Biotin operon repressor, helix-turn-helix domain GO:0006355 KEGG: 00780+6.3.4.15 AF_0074 f20837c734c2f6d3e36df143bf62b8a3 299 Pfam PF03099 Biotin/lipoate A/B protein ligase family 90 200 3.1E-14 T 31-10-2018 IPR004143 Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain GO:0006464 KEGG: 00785+2.3.1.181|MetaCyc: PWY-6987|MetaCyc: PWY-7382 AF_0074 f20837c734c2f6d3e36df143bf62b8a3 299 Pfam PF08279 HTH domain 16 58 7.0E-13 T 31-10-2018 IPR013196 Helix-turn-helix, type 11 AF_0074 f20837c734c2f6d3e36df143bf62b8a3 299 Pfam PF02237 Biotin protein ligase C terminal domain 258 297 2.4E-6 T 31-10-2018 IPR003142 Biotin protein ligase, C-terminal GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AF_0074 f20837c734c2f6d3e36df143bf62b8a3 299 SUPERFAMILY SSF46785 7 54 2.25E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0074 f20837c734c2f6d3e36df143bf62b8a3 299 Gene3D G3DSA:2.30.30.100 257 299 2.8E-6 T 31-10-2018 AF_0074 f20837c734c2f6d3e36df143bf62b8a3 299 TIGRFAM TIGR00121 birA_ligase: biotin--[acetyl-CoA-carboxylase] ligase 82 297 8.7E-77 T 31-10-2018 IPR004408 Biotin--acetyl-CoA-carboxylase ligase GO:0004077|GO:0006464 KEGG: 00780+6.3.4.15|Reactome: R-HSA-196780|Reactome: R-HSA-3371599 AF_0013 42d5d1c7b8937c1886e128a25dc3a1f8 399 Gene3D G3DSA:1.20.1250.20 195 397 1.2E-22 T 31-10-2018 AF_0013 42d5d1c7b8937c1886e128a25dc3a1f8 399 Pfam PF07690 Major Facilitator Superfamily 17 349 1.4E-35 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AF_0013 42d5d1c7b8937c1886e128a25dc3a1f8 399 Gene3D G3DSA:1.20.1250.20 6 194 1.1E-25 T 31-10-2018 AF_0013 42d5d1c7b8937c1886e128a25dc3a1f8 399 SUPERFAMILY SSF103473 5 397 4.32E-58 T 31-10-2018 IPR036259 MFS transporter superfamily AF_0599 c90e2337644cb4790cd62c03bdb67f03 250 Gene3D G3DSA:3.90.550.10 13 189 1.2E-9 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0599 c90e2337644cb4790cd62c03bdb67f03 250 SUPERFAMILY SSF53448 41 248 4.11E-22 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0599 c90e2337644cb4790cd62c03bdb67f03 250 Pfam PF00535 Glycosyl transferase family 2 86 140 3.6E-6 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AF_0569 51c19c28cb06f811b9762fc220a562e7 60 SUPERFAMILY SSF47598 4 47 1.78E-9 T 31-10-2018 IPR010985 Ribbon-helix-helix GO:0006355 AF_0569 51c19c28cb06f811b9762fc220a562e7 60 Gene3D G3DSA:1.10.8.1250 13 57 6.5E-5 T 31-10-2018 IPR038296 Antitoxin ParD superfamily AF_0569 51c19c28cb06f811b9762fc220a562e7 60 Pfam PF01402 Ribbon-helix-helix protein, copG family 7 45 8.9E-8 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 AF_2309 36986f63755f9ad86297680025e61d79 537 Pfam PF07690 Major Facilitator Superfamily 65 402 1.8E-20 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AF_2309 36986f63755f9ad86297680025e61d79 537 SUPERFAMILY SSF103473 59 469 2.35E-40 T 31-10-2018 IPR036259 MFS transporter superfamily AF_2309 36986f63755f9ad86297680025e61d79 537 Gene3D G3DSA:1.20.1250.20 24 233 8.2E-11 T 31-10-2018 AF_2309 36986f63755f9ad86297680025e61d79 537 Gene3D G3DSA:1.20.1250.20 245 477 3.1E-15 T 31-10-2018 AF_1355 46bbe76e94f7b002cbdff85f59ddc121 315 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 11 53 1.8E-11 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AF_1355 46bbe76e94f7b002cbdff85f59ddc121 315 SUPERFAMILY SSF109755 124 311 5.38E-25 T 31-10-2018 AF_1355 46bbe76e94f7b002cbdff85f59ddc121 315 Gene3D G3DSA:2.10.260.10 13 49 1.5E-6 T 31-10-2018 AF_1355 46bbe76e94f7b002cbdff85f59ddc121 315 SUPERFAMILY SSF89447 14 52 2.62E-7 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily AF_1355 46bbe76e94f7b002cbdff85f59ddc121 315 Gene3D G3DSA:1.20.58.220 133 228 1.8E-13 T 31-10-2018 IPR038078 PhoU-like domain superfamily AF_1355 46bbe76e94f7b002cbdff85f59ddc121 315 Pfam PF01895 PhoU domain 230 308 1.6E-5 T 31-10-2018 IPR026022 PhoU domain AF_1355 46bbe76e94f7b002cbdff85f59ddc121 315 Pfam PF01895 PhoU domain 135 219 1.3E-13 T 31-10-2018 IPR026022 PhoU domain AF_1355 46bbe76e94f7b002cbdff85f59ddc121 315 SMART SM00966 10 55 2.9E-12 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AF_1782 f420be0ce14beead173e391c17c3a5ac 76 Pfam PF04010 Protein of unknown function (DUF357) 25 71 3.7E-15 T 31-10-2018 IPR023140 Domain of unknown function DUF357 AF_1782 f420be0ce14beead173e391c17c3a5ac 76 SUPERFAMILY SSF158372 2 72 2.09E-22 T 31-10-2018 IPR036809 AF1782-like superfamily AF_1782 f420be0ce14beead173e391c17c3a5ac 76 Gene3D G3DSA:1.20.1270.90 1 76 1.1E-36 T 31-10-2018 AF_1503 1543d168f5f356e2e67aa174b5c87bd8 338 SMART SM00304 278 331 1.7E-11 T 31-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AF_1503 1543d168f5f356e2e67aa174b5c87bd8 338 SUPERFAMILY SSF158472 279 327 1.57E-12 T 31-10-2018 AF_1503 1543d168f5f356e2e67aa174b5c87bd8 338 Pfam PF00672 HAMP domain 279 326 5.4E-11 T 31-10-2018 IPR003660 HAMP domain GO:0007165|GO:0016021 AF_1503 1543d168f5f356e2e67aa174b5c87bd8 338 Gene3D G3DSA:1.20.1480.50 237 338 1.2E-40 T 31-10-2018 AF_1491 94c88c9aee161daa62c6155896b6ad85 339 Gene3D G3DSA:3.90.105.20 106 185 9.8E-64 T 31-10-2018 AF_1491 94c88c9aee161daa62c6155896b6ad85 339 Pfam PF00466 Ribosomal protein L10 9 104 1.8E-23 T 31-10-2018 IPR001790 Ribosomal protein L10P GO:0005622|GO:0042254 AF_1491 94c88c9aee161daa62c6155896b6ad85 339 Gene3D G3DSA:3.30.70.1730 19 209 9.8E-64 T 31-10-2018 AF_1491 94c88c9aee161daa62c6155896b6ad85 339 Hamap MF_00280 50S ribosomal protein L10 [rpl10]. 5 282 33.521 T 31-10-2018 IPR022909 50S ribosomal protein L10, archaea AF_1491 94c88c9aee161daa62c6155896b6ad85 339 SUPERFAMILY SSF160369 9 139 1.57E-23 T 31-10-2018 AF_0347 bc200e527c60f0514f6c90faccce8178 319 TIGRFAM TIGR00816 tdt: C4-dicarboxylate transporter/malic acid transport protein 6 318 1.6E-109 T 31-10-2018 IPR011552 Tellurite resistance protein TehA/malic acid transport protein GO:0016021 AF_0347 bc200e527c60f0514f6c90faccce8178 319 Gene3D G3DSA:1.50.10.150 2 319 1.9E-37 T 31-10-2018 IPR038665 Voltage-dependent anion channel superfamily AF_0347 bc200e527c60f0514f6c90faccce8178 319 Pfam PF03595 Voltage-dependent anion channel 6 312 9.4E-54 T 31-10-2018 IPR004695 Voltage-dependent anion channel GO:0016021|GO:0055085 AF_1271 683d3dfe42fa2816e72aa07ddbefb2c4 180 SUPERFAMILY SSF52255 29 179 2.88E-37 T 31-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 AF_1271 683d3dfe42fa2816e72aa07ddbefb2c4 180 Gene3D G3DSA:3.40.50.7700 27 180 4.3E-53 T 31-10-2018 IPR035893 PurE domain superfamily Reactome: R-HSA-73817 AF_1271 683d3dfe42fa2816e72aa07ddbefb2c4 180 Hamap MF_02045 Phosphoribosylaminoimidazole carboxylase [purE]. 27 180 37.416 T 31-10-2018 IPR033626 Class II PurE GO:0006189 KEGG: 00230+4.1.1.21|MetaCyc: PWY-6124|Reactome: R-HSA-73817 AF_1271 683d3dfe42fa2816e72aa07ddbefb2c4 180 PIRSF PIRSF001338 24 180 1.4E-57 T 31-10-2018 IPR024694 PurE, prokaryotic type GO:0006189 KEGG: 00230+5.4.99.18|MetaCyc: PWY-6123|MetaCyc: PWY-7234 AF_1271 683d3dfe42fa2816e72aa07ddbefb2c4 180 Pfam PF00731 AIR carboxylase 30 170 1.5E-40 T 31-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AF_1271 683d3dfe42fa2816e72aa07ddbefb2c4 180 TIGRFAM TIGR01162 purE: phosphoribosylaminoimidazole carboxylase, catalytic subunit 30 179 2.7E-49 T 31-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AF_1271 683d3dfe42fa2816e72aa07ddbefb2c4 180 SMART SM01001 27 172 9.3E-45 T 31-10-2018 IPR000031 PurE domain GO:0006189 Reactome: R-HSA-73817 AF_0167 921ec20a4fe1008ee7a1e9e8697c6923 336 Gene3D G3DSA:3.60.15.10 1 187 9.0E-63 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_0167 921ec20a4fe1008ee7a1e9e8697c6923 336 PIRSF PIRSF005243 1 336 3.5E-106 T 31-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 AF_0167 921ec20a4fe1008ee7a1e9e8697c6923 336 SUPERFAMILY SSF52218 191 333 3.67E-34 T 31-10-2018 IPR029039 Flavoprotein-like superfamily AF_0167 921ec20a4fe1008ee7a1e9e8697c6923 336 SMART SM00849 10 168 9.8E-17 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_0167 921ec20a4fe1008ee7a1e9e8697c6923 336 SUPERFAMILY SSF56281 5 222 2.88E-40 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_0167 921ec20a4fe1008ee7a1e9e8697c6923 336 Pfam PF00258 Flavodoxin 196 322 5.3E-7 T 31-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 AF_0167 921ec20a4fe1008ee7a1e9e8697c6923 336 Gene3D G3DSA:3.40.50.360 189 332 4.8E-32 T 31-10-2018 IPR029039 Flavoprotein-like superfamily AF_2145 d5d27135a461d1e5385a2faaba5a91c8 91 Gene3D G3DSA:3.40.30.10 1 82 7.9E-17 T 31-10-2018 AF_2145 d5d27135a461d1e5385a2faaba5a91c8 91 Pfam PF13192 Thioredoxin domain 5 79 4.9E-16 T 31-10-2018 IPR012336 Thioredoxin-like fold AF_2145 d5d27135a461d1e5385a2faaba5a91c8 91 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 31-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 AF_2145 d5d27135a461d1e5385a2faaba5a91c8 91 SUPERFAMILY SSF52833 5 84 3.11E-17 T 31-10-2018 IPR036249 Thioredoxin-like superfamily AF_2145 d5d27135a461d1e5385a2faaba5a91c8 91 TIGRFAM TIGR00411 redox_disulf_1: redox-active disulfide protein 1 2 82 3.3E-42 T 31-10-2018 IPR004502 Thioredoxins/glutaredoxin GO:0009055|GO:0015035|GO:0045454 AF_0546 434939e0cb6e9c5c72cb76ccbca6982f 244 Pfam PF02665 Nitrate reductase gamma subunit 91 227 6.0E-11 T 31-10-2018 IPR023234 NarG-like domain AF_0546 434939e0cb6e9c5c72cb76ccbca6982f 244 SUPERFAMILY SSF103501 21 243 3.66E-27 T 31-10-2018 IPR036197 NarG-like superfamily AF_0546 434939e0cb6e9c5c72cb76ccbca6982f 244 Gene3D G3DSA:1.20.950.20 84 231 1.0E-14 T 31-10-2018 AF_0967 e977f113d8c42548eb33964117096ebc 400 SUPERFAMILY SSF53901 16 240 6.62E-33 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0967 e977f113d8c42548eb33964117096ebc 400 SUPERFAMILY SSF53901 248 376 5.26E-18 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0967 e977f113d8c42548eb33964117096ebc 400 PIRSF PIRSF000429 12 396 8.0E-30 T 31-10-2018 IPR002155 Thiolase GO:0016747 AF_0967 e977f113d8c42548eb33964117096ebc 400 Pfam PF00108 Thiolase, N-terminal domain 17 135 3.4E-9 T 31-10-2018 IPR020616 Thiolase, N-terminal GO:0016747 AF_0967 e977f113d8c42548eb33964117096ebc 400 Gene3D G3DSA:3.40.47.10 12 398 1.7E-88 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_2317 177a672d88a77ca67d11d1cf0dee89dd 199 Hamap MF_00756 Ribonuclease P protein component 3 [rnp3]. 6 184 19.155 T 31-10-2018 IPR023539 Ribonuclease P, protein component 3, archaeal GO:0001682|GO:0004526 AF_2317 177a672d88a77ca67d11d1cf0dee89dd 199 Gene3D G3DSA:3.20.20.140 7 178 3.1E-30 T 31-10-2018 AF_2317 177a672d88a77ca67d11d1cf0dee89dd 199 ProDom PD016938 P COMPONENT RIBONUCLEASE RNASE HYDROLASE PROCESSING TRNA SUBUNIT SIMILAR P/RNASE 90 168 1.0E-38 T 31-10-2018 AF_2317 177a672d88a77ca67d11d1cf0dee89dd 199 SUPERFAMILY SSF89550 16 177 5.1E-22 T 31-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AF_2317 177a672d88a77ca67d11d1cf0dee89dd 199 Pfam PF01876 RNase P subunit p30 59 168 1.1E-16 T 31-10-2018 IPR002738 RNase P subunit p30 GO:0004540|GO:0008033 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AF_0259 da26a5db41407af33b3681cb72e24af2 123 Pfam PF01909 Nucleotidyltransferase domain 7 80 1.2E-12 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AF_0259 da26a5db41407af33b3681cb72e24af2 123 Gene3D G3DSA:3.30.460.10 2 97 1.3E-16 T 31-10-2018 AF_0259 da26a5db41407af33b3681cb72e24af2 123 SUPERFAMILY SSF81301 4 93 2.24E-17 T 31-10-2018 AF_1793 310bdac997ef4d3d264294b2ec017fbf 70 SMART SM00530 4 59 1.4E-17 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AF_1793 310bdac997ef4d3d264294b2ec017fbf 70 Gene3D G3DSA:1.10.260.40 1 65 1.4E-27 T 31-10-2018 AF_1793 310bdac997ef4d3d264294b2ec017fbf 70 Pfam PF01381 Helix-turn-helix 5 59 3.7E-17 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AF_1793 310bdac997ef4d3d264294b2ec017fbf 70 SUPERFAMILY SSF47413 3 64 1.05E-19 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AF_1153 de7a21e46fd93f3dbd7c105f025a91ad 363 Pfam PF04015 Domain of unknown function (DUF362) 49 316 5.2E-39 T 31-10-2018 IPR007160 Domain of unknown function DUF362 AF_1153 de7a21e46fd93f3dbd7c105f025a91ad 363 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 204 215 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1153 de7a21e46fd93f3dbd7c105f025a91ad 363 Pfam PF00037 4Fe-4S binding domain 197 220 5.4E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1153 de7a21e46fd93f3dbd7c105f025a91ad 363 Gene3D G3DSA:3.30.70.20 198 246 2.6E-9 T 31-10-2018 AF_1153 de7a21e46fd93f3dbd7c105f025a91ad 363 SUPERFAMILY SSF54862 157 298 4.19E-16 T 31-10-2018 AF_0614 c33264da1b6759e65b2c5904d4c28c56 93 Gene3D G3DSA:3.30.460.10 1 93 6.9E-39 T 31-10-2018 AF_0614 c33264da1b6759e65b2c5904d4c28c56 93 Pfam PF01909 Nucleotidyltransferase domain 1 89 2.9E-14 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AF_0614 c33264da1b6759e65b2c5904d4c28c56 93 SUPERFAMILY SSF81301 1 86 7.63E-22 T 31-10-2018 AF_2258 b8f02506a7732d9f1d0726eeb0b41924 503 Pfam PF07690 Major Facilitator Superfamily 20 409 7.0E-48 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AF_2258 b8f02506a7732d9f1d0726eeb0b41924 503 Gene3D G3DSA:1.20.1250.20 260 433 6.4E-20 T 31-10-2018 AF_2258 b8f02506a7732d9f1d0726eeb0b41924 503 PRINTS PR01036 Tetracycline resistance protein TetB signature 138 162 2.0E-8 T 31-10-2018 AF_2258 b8f02506a7732d9f1d0726eeb0b41924 503 PRINTS PR01036 Tetracycline resistance protein TetB signature 17 41 2.0E-8 T 31-10-2018 AF_2258 b8f02506a7732d9f1d0726eeb0b41924 503 PRINTS PR01036 Tetracycline resistance protein TetB signature 108 128 2.0E-8 T 31-10-2018 AF_2258 b8f02506a7732d9f1d0726eeb0b41924 503 PRINTS PR01036 Tetracycline resistance protein TetB signature 203 221 2.0E-8 T 31-10-2018 AF_2258 b8f02506a7732d9f1d0726eeb0b41924 503 PRINTS PR01036 Tetracycline resistance protein TetB signature 400 419 2.0E-8 T 31-10-2018 AF_2258 b8f02506a7732d9f1d0726eeb0b41924 503 TIGRFAM TIGR00711 efflux_EmrB: drug resistance MFS transporter, drug:H+ antiporter-2 (14 Spanner) (DHA2) family 15 422 2.4E-91 T 31-10-2018 IPR004638 Drug resistance transporter EmrB/QacA subfamily GO:0016021|GO:0022857|GO:0055085 AF_2258 b8f02506a7732d9f1d0726eeb0b41924 503 SUPERFAMILY SSF103473 8 486 1.05E-67 T 31-10-2018 IPR036259 MFS transporter superfamily AF_2258 b8f02506a7732d9f1d0726eeb0b41924 503 Gene3D G3DSA:1.20.1720.10 16 206 9.1E-45 T 31-10-2018 AF_1538 f585b58128163ab34f5a89b91f7316b5 486 Pfam PF02667 Short chain fatty acid transporter 9 484 9.7E-223 T 31-10-2018 IPR006160 Short chain fatty acid transporter AtoE AF_1538 f585b58128163ab34f5a89b91f7316b5 486 TIGRFAM TIGR00366 TIGR00366: TIGR00366 family protein 11 472 1.8E-218 T 31-10-2018 IPR006161 Conserved hypothetical protein CHP00336 AF_0735 c4582b61b8eed5799f060d9ec556bbf3 457 SUPERFAMILY SSF64182 4 456 8.02E-59 T 31-10-2018 IPR038763 DHH phosphoesterase superfamily AF_0735 c4582b61b8eed5799f060d9ec556bbf3 457 Pfam PF02272 DHHA1 domain 349 451 1.2E-19 T 31-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 AF_0735 c4582b61b8eed5799f060d9ec556bbf3 457 Gene3D G3DSA:3.10.310.30 334 454 3.4E-8 T 31-10-2018 AF_0735 c4582b61b8eed5799f060d9ec556bbf3 457 Gene3D G3DSA:3.90.1640.30 1 204 3.2E-14 T 31-10-2018 AF_1811 57e1b80a1e887cb4269229aab717839d 157 SUPERFAMILY SSF52335 2 154 1.96E-34 T 31-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AF_1811 57e1b80a1e887cb4269229aab717839d 157 SMART SM00851 12 114 6.4E-21 T 31-10-2018 IPR011607 Methylglyoxal synthase-like domain AF_1811 57e1b80a1e887cb4269229aab717839d 157 Gene3D G3DSA:3.40.50.1380 1 154 6.8E-37 T 31-10-2018 IPR036914 Methylglyoxal synthase-like domain superfamily AF_1811 57e1b80a1e887cb4269229aab717839d 157 Pfam PF02142 MGS-like domain 13 112 4.7E-19 T 31-10-2018 IPR011607 Methylglyoxal synthase-like domain AF_1721 2bf91031c52ac07241f744dd47eda0c5 528 Pfam PF05228 CHASE4 domain 51 201 2.8E-38 T 31-10-2018 IPR007892 CHASE4 AF_1721 2bf91031c52ac07241f744dd47eda0c5 528 Gene3D G3DSA:1.10.287.130 273 390 1.3E-7 T 31-10-2018 AF_1721 2bf91031c52ac07241f744dd47eda0c5 528 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 434 522 9.0E-18 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_1721 2bf91031c52ac07241f744dd47eda0c5 528 SMART SM00387 429 528 2.2E-22 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_1721 2bf91031c52ac07241f744dd47eda0c5 528 Gene3D G3DSA:3.30.565.10 398 528 4.0E-25 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_1721 2bf91031c52ac07241f744dd47eda0c5 528 SUPERFAMILY SSF55874 403 523 7.07E-24 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_1721 2bf91031c52ac07241f744dd47eda0c5 528 SMART SM00388 334 396 7.5E-4 T 31-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AF_1721 2bf91031c52ac07241f744dd47eda0c5 528 PRINTS PR00344 Bacterial sensor protein C-terminal signature 492 510 1.1E-7 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1721 2bf91031c52ac07241f744dd47eda0c5 528 PRINTS PR00344 Bacterial sensor protein C-terminal signature 465 479 1.1E-7 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_1662 05f586913fcdf303fc89b2dd9ade520e 89 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 32 70 2.0E-6 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal AF_1662 05f586913fcdf303fc89b2dd9ade520e 89 SUPERFAMILY SSF46785 16 73 1.53E-9 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1662 05f586913fcdf303fc89b2dd9ade520e 89 Gene3D G3DSA:1.10.10.10 4 85 1.2E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_2246 72bb6c9dffdaa855a18c1a96a5dcfdc6 177 Gene3D G3DSA:1.10.15.40 108 163 3.6E-20 T 31-10-2018 AF_2246 72bb6c9dffdaa855a18c1a96a5dcfdc6 177 Pfam PF04060 Putative Fe-S cluster 118 150 1.3E-14 T 31-10-2018 IPR007202 4Fe-4S domain GO:0051536 AF_0234 5f93b745b009565939c79812bbe6bd27 133 SMART SM00849 7 131 3.9E-8 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_0234 5f93b745b009565939c79812bbe6bd27 133 Gene3D G3DSA:3.60.15.10 2 131 3.2E-30 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_0234 5f93b745b009565939c79812bbe6bd27 133 Pfam PF00753 Metallo-beta-lactamase superfamily 7 129 1.1E-21 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_0234 5f93b745b009565939c79812bbe6bd27 133 SUPERFAMILY SSF56281 7 129 6.29E-28 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_2047 eafa781120dbe3f91d643514bb4d241c 480 SUPERFAMILY SSF55831 251 469 1.05E-44 T 31-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AF_2047 eafa781120dbe3f91d643514bb4d241c 480 Gene3D G3DSA:3.30.572.10 105 235 1.2E-7 T 31-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AF_2047 eafa781120dbe3f91d643514bb4d241c 480 Gene3D G3DSA:3.30.572.10 278 476 1.9E-26 T 31-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AF_2047 eafa781120dbe3f91d643514bb4d241c 480 SUPERFAMILY SSF55831 24 257 8.9E-34 T 31-10-2018 IPR036926 Thymidylate synthase/dCMP hydroxymethylase superfamily KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AF_2047 eafa781120dbe3f91d643514bb4d241c 480 Pfam PF00303 Thymidylate synthase 340 465 6.5E-16 T 31-10-2018 IPR023451 Thymidylate synthase/dCMP hydroxymethylase domain KEGG: 00240+2.1.1.45|KEGG: 00670+2.1.1.45|MetaCyc: PWY-3841|MetaCyc: PWY-7184|MetaCyc: PWY-7187|MetaCyc: PWY-7198|MetaCyc: PWY-7199|MetaCyc: PWY-7210|Reactome: R-HSA-499943|Reactome: R-HSA-539107 AF_2021 55f1bfa1531c8145a7ce93bcb1ddca2b 363 Pfam PF06723 MreB/Mbl protein 35 328 1.7E-15 T 31-10-2018 IPR004753 Cell shape determining protein MreB GO:0000902 AF_2021 55f1bfa1531c8145a7ce93bcb1ddca2b 363 SUPERFAMILY SSF53067 172 332 1.3E-19 T 31-10-2018 AF_2021 55f1bfa1531c8145a7ce93bcb1ddca2b 363 SUPERFAMILY SSF53067 32 171 1.77E-24 T 31-10-2018 AF_2021 55f1bfa1531c8145a7ce93bcb1ddca2b 363 Gene3D G3DSA:3.30.420.40 171 320 1.0E-30 T 31-10-2018 AF_2021 55f1bfa1531c8145a7ce93bcb1ddca2b 363 Gene3D G3DSA:3.90.640.10 202 261 1.0E-30 T 31-10-2018 AF_2021 55f1bfa1531c8145a7ce93bcb1ddca2b 363 Gene3D G3DSA:3.30.420.40 35 321 1.0E-30 T 31-10-2018 AF_2061 848d64f8decfd1bf606fd0f785110ca0 206 Pfam PF01983 Guanylyl transferase CofC like 1 205 1.8E-95 T 31-10-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 AF_2061 848d64f8decfd1bf606fd0f785110ca0 206 Gene3D G3DSA:3.90.550.10 1 157 5.4E-33 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_2061 848d64f8decfd1bf606fd0f785110ca0 206 TIGRFAM TIGR03552 F420_cofC: 2-phospho-L-lactate guanylyltransferase 2 178 3.1E-55 T 31-10-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 AF_2061 848d64f8decfd1bf606fd0f785110ca0 206 Hamap MF_02114 2-phospho-L-lactate guanylyltransferase [cofC]. 1 186 26.805 T 31-10-2018 IPR002835 2-phospho-L-lactate guanylyltransferase, CofC GO:0016779 KEGG: 00680+2.7.7.68|MetaCyc: PWY-5198 AF_2061 848d64f8decfd1bf606fd0f785110ca0 206 SUPERFAMILY SSF53448 2 192 2.18E-34 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0995 605ae306530708c1c8927d763227c2fe 651 Gene3D G3DSA:1.20.81.30 434 545 1.1E-10 T 31-10-2018 AF_0995 605ae306530708c1c8927d763227c2fe 651 Pfam PF00482 Type II secretion system (T2SS), protein F 147 273 4.3E-23 T 31-10-2018 IPR018076 Type II secretion system F domain AF_0995 605ae306530708c1c8927d763227c2fe 651 Pfam PF00482 Type II secretion system (T2SS), protein F 439 564 1.5E-21 T 31-10-2018 IPR018076 Type II secretion system F domain AF_1588 e90c14c031a7b30261815d1a0d9b1a7a 408 Gene3D G3DSA:3.30.360.10 132 326 4.7E-78 T 31-10-2018 AF_1588 e90c14c031a7b30261815d1a0d9b1a7a 408 Pfam PF16653 Saccharopine dehydrogenase C-terminal domain 179 375 1.4E-7 T 31-10-2018 IPR032095 Saccharopine dehydrogenase, C-terminal Reactome: R-HSA-71064 AF_1588 e90c14c031a7b30261815d1a0d9b1a7a 408 Pfam PF03435 Saccharopine dehydrogenase NADP binding domain 4 126 2.5E-19 T 31-10-2018 IPR005097 Saccharopine dehydrogenase, NADP binding domain GO:0016491|GO:0055114 AF_1588 e90c14c031a7b30261815d1a0d9b1a7a 408 Gene3D G3DSA:3.40.50.720 4 364 4.7E-78 T 31-10-2018 AF_1588 e90c14c031a7b30261815d1a0d9b1a7a 408 SUPERFAMILY SSF51735 1 160 1.6E-21 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1887 e6b66355fac8bb3c620cd84dfa997a7e 604 Pfam PF04566 RNA polymerase Rpb2, domain 4 6 67 5.5E-24 T 31-10-2018 IPR007646 RNA polymerase Rpb2, domain 4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1887 e6b66355fac8bb3c620cd84dfa997a7e 604 ProSitePatterns PS01166 RNA polymerases beta chain signature. 360 372 - T 31-10-2018 IPR007121 RNA polymerase, beta subunit, conserved site GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1887 e6b66355fac8bb3c620cd84dfa997a7e 604 Pfam PF04560 RNA polymerase Rpb2, domain 7 509 599 3.7E-33 T 31-10-2018 IPR007641 RNA polymerase Rpb2, domain 7 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1887 e6b66355fac8bb3c620cd84dfa997a7e 604 Pfam PF00562 RNA polymerase Rpb2, domain 6 137 507 3.0E-128 T 31-10-2018 IPR007120 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1887 e6b66355fac8bb3c620cd84dfa997a7e 604 TIGRFAM TIGR03670 rpoB_arch: DNA-directed RNA polymerase subunit B 6 603 0.0 T 31-10-2018 IPR019969 DNA-directed RNA polymerase subunit B (Rpo2) GO:0003677|GO:0003899|GO:0006351|GO:0008270 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1887 e6b66355fac8bb3c620cd84dfa997a7e 604 Gene3D G3DSA:3.90.1800.10 494 602 1.1E-42 T 31-10-2018 AF_1887 e6b66355fac8bb3c620cd84dfa997a7e 604 Gene3D G3DSA:3.90.1070.20 1 55 1.4E-18 T 31-10-2018 AF_1887 e6b66355fac8bb3c620cd84dfa997a7e 604 Gene3D G3DSA:2.40.270.10 137 493 8.8E-139 T 31-10-2018 IPR037033 DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1887 e6b66355fac8bb3c620cd84dfa997a7e 604 SUPERFAMILY SSF64484 4 602 1.31E-234 T 31-10-2018 AF_1887 e6b66355fac8bb3c620cd84dfa997a7e 604 Gene3D G3DSA:2.40.50.150 166 356 8.8E-139 T 31-10-2018 IPR014724 RNA polymerase Rpb2, OB-fold GO:0003899 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1887 e6b66355fac8bb3c620cd84dfa997a7e 604 Pfam PF04567 RNA polymerase Rpb2, domain 5 89 128 5.8E-9 T 31-10-2018 IPR007647 RNA polymerase Rpb2, domain 5 GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_1030 19f47bb21258de58a93b06d28bde66e0 527 Pfam PF05872 Bacterial protein of unknown function (DUF853) 379 478 1.5E-6 T 31-10-2018 IPR033186 Helicase HerA-like C-terminal AF_1030 19f47bb21258de58a93b06d28bde66e0 527 Pfam PF09378 HAS barrel domain 4 95 1.2E-16 T 31-10-2018 IPR018538 Helicase HerA, barrel domain AF_1030 19f47bb21258de58a93b06d28bde66e0 527 Pfam PF01935 Domain of unknown function DUF87 129 356 1.0E-47 T 31-10-2018 IPR002789 Helicase HerA, central domain AF_1030 19f47bb21258de58a93b06d28bde66e0 527 Gene3D G3DSA:3.40.50.300 115 295 1.3E-21 T 31-10-2018 AF_1030 19f47bb21258de58a93b06d28bde66e0 527 Gene3D G3DSA:3.40.50.300 301 507 2.5E-56 T 31-10-2018 AF_1030 19f47bb21258de58a93b06d28bde66e0 527 SUPERFAMILY SSF52540 97 498 3.1E-39 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0634 79ba18a27a7b0814ef0dc4b88009c231 308 SUPERFAMILY SSF51735 4 151 1.13E-13 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0634 79ba18a27a7b0814ef0dc4b88009c231 308 Gene3D G3DSA:3.40.50.720 1 154 6.0E-18 T 31-10-2018 AF_1432 bbcc4bce374b700e43378e20c179992d 173 SUPERFAMILY SSF109604 7 172 1.13E-33 T 31-10-2018 AF_1432 bbcc4bce374b700e43378e20c179992d 173 Gene3D G3DSA:1.10.3210.10 1 173 2.3E-66 T 31-10-2018 AF_1432 bbcc4bce374b700e43378e20c179992d 173 Pfam PF13023 HD domain 17 96 1.5E-16 T 31-10-2018 IPR006674 HD domain AF_1432 bbcc4bce374b700e43378e20c179992d 173 SMART SM00471 35 138 1.2E-9 T 31-10-2018 IPR003607 HD/PDEase domain AF_1787 d49aea8ddd6c474ae038b59c657b1ea5 309 SMART SM00530 130 184 2.9E-10 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AF_1787 d49aea8ddd6c474ae038b59c657b1ea5 309 SUPERFAMILY SSF47413 128 178 7.24E-11 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AF_1787 d49aea8ddd6c474ae038b59c657b1ea5 309 Hamap MF_00584 Putative HTH-type transcriptional regulatory protein . 1 297 29.335 T 31-10-2018 IPR020886 Transcription regulator HTH, Cro/C1-type DNA-binding GO:0003700|GO:0006355 AF_1787 d49aea8ddd6c474ae038b59c657b1ea5 309 Pfam PF01381 Helix-turn-helix 131 178 3.8E-11 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AF_1787 d49aea8ddd6c474ae038b59c657b1ea5 309 Gene3D G3DSA:1.10.260.40 123 190 5.0E-12 T 31-10-2018 AF_0745 d8d4c6198e9a6b1fee05c1b7a594a617 299 ProSitePatterns PS00912 Dihydroorotate dehydrogenase signature 2. 236 256 - T 31-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 AF_0745 d8d4c6198e9a6b1fee05c1b7a594a617 299 Gene3D G3DSA:3.20.20.70 3 296 1.1E-76 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0745 d8d4c6198e9a6b1fee05c1b7a594a617 299 ProSitePatterns PS00911 Dihydroorotate dehydrogenase signature 1. 39 58 - T 31-10-2018 IPR001295 Dihydroorotate dehydrogenase, conserved site GO:0004152|GO:0006207|GO:0055114 Reactome: R-HSA-500753 AF_0745 d8d4c6198e9a6b1fee05c1b7a594a617 299 Hamap MF_00224 Dihydroorotate dehydrogenase [pyrD]. 4 297 33.891 T 31-10-2018 IPR024920 Dihydroorotate dehydrogenase, class 1 GO:0004152|GO:0005737|GO:0006221 AF_0745 d8d4c6198e9a6b1fee05c1b7a594a617 299 Pfam PF01180 Dihydroorotate dehydrogenase 4 278 6.9E-60 T 31-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 AF_0745 d8d4c6198e9a6b1fee05c1b7a594a617 299 PIRSF PIRSF000164 1 299 9.6E-81 T 31-10-2018 IPR012135 Dihydroorotate dehydrogenase, class 1/ 2 GO:0004152|GO:0006222|GO:0055114 AF_0745 d8d4c6198e9a6b1fee05c1b7a594a617 299 TIGRFAM TIGR01037 pyrD_sub1_fam: dihydroorotate dehydrogenase family protein 4 298 7.5E-139 T 31-10-2018 IPR005720 Dihydroorotate dehydrogenase domain GO:0005737|GO:0016627|GO:0055114 AF_0745 d8d4c6198e9a6b1fee05c1b7a594a617 299 SUPERFAMILY SSF51395 3 297 1.28E-66 T 31-10-2018 AF_0222 673dc883b444055f0f55917ded4f94ad 281 Pfam PF00005 ABC transporter 71 204 9.8E-30 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0222 673dc883b444055f0f55917ded4f94ad 281 Gene3D G3DSA:3.40.50.300 53 278 4.8E-60 T 31-10-2018 AF_0222 673dc883b444055f0f55917ded4f94ad 281 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 253 275 5.5E-6 T 31-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AF_0222 673dc883b444055f0f55917ded4f94ad 281 SMART SM00382 80 274 1.0E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0222 673dc883b444055f0f55917ded4f94ad 281 ProSitePatterns PS00211 ABC transporters family signature. 177 191 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_0222 673dc883b444055f0f55917ded4f94ad 281 SUPERFAMILY SSF52540 55 275 7.78E-60 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0983 b04964c45c9975c9480a53bf7e804e56 228 Pfam PF03379 CcmB protein 22 210 7.3E-11 T 31-10-2018 IPR003544 Cytochrome c-type biogenesis protein CcmB GO:0015232|GO:0015886|GO:0016020|GO:0017004 AF_2155 d9310cee1c8e73991f3b6c374f477bfe 234 SMART SM00849 18 203 7.3E-14 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_2155 d9310cee1c8e73991f3b6c374f477bfe 234 Pfam PF00753 Metallo-beta-lactamase superfamily 18 203 6.1E-18 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_2155 d9310cee1c8e73991f3b6c374f477bfe 234 Gene3D G3DSA:3.60.15.10 2 234 6.4E-49 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_2155 d9310cee1c8e73991f3b6c374f477bfe 234 SUPERFAMILY SSF56281 2 234 3.54E-47 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_1054 9cce5949c866854983e0a8361477a384 203 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 10 30 9.6E-4 T 31-10-2018 IPR013373 Flagellin/pilin, N-terminal AF_1054 9cce5949c866854983e0a8361477a384 203 Pfam PF01917 Archaebacterial flagellin 11 188 1.2E-44 T 31-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 AF_0359 4ef414b30a0270d7626901cc2536fe8d 79 SUPERFAMILY SSF50346 2 74 2.62E-12 T 31-10-2018 IPR011033 PRC-barrel-like superfamily AF_0359 4ef414b30a0270d7626901cc2536fe8d 79 Gene3D G3DSA:2.30.30.240 5 77 7.5E-8 T 31-10-2018 AF_0359 4ef414b30a0270d7626901cc2536fe8d 79 Pfam PF05239 PRC-barrel domain 5 76 4.3E-11 T 31-10-2018 IPR027275 PRC-barrel domain AF_0921 b2fca893616c9f53de87bb8fa4f101fc 240 Pfam PF01979 Amidohydrolase family 42 195 4.6E-11 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AF_0921 b2fca893616c9f53de87bb8fa4f101fc 240 SUPERFAMILY SSF51556 2 230 2.92E-53 T 31-10-2018 IPR032466 Metal-dependent hydrolase AF_0921 b2fca893616c9f53de87bb8fa4f101fc 240 Gene3D G3DSA:3.20.20.140 1 239 1.2E-60 T 31-10-2018 AF_1922 b439a8c149e5bda1c1c085591e077ea1 237 Pfam PF03947 Ribosomal Proteins L2, C-terminal domain 90 220 1.4E-46 T 31-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 AF_1922 b439a8c149e5bda1c1c085591e077ea1 237 Gene3D G3DSA:4.10.950.10 160 237 1.3E-39 T 31-10-2018 IPR014726 Ribosomal protein L2, domain 3 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1922 b439a8c149e5bda1c1c085591e077ea1 237 ProSitePatterns PS00467 Ribosomal protein L2 signature. 187 198 - T 31-10-2018 IPR022671 Ribosomal protein L2, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1922 b439a8c149e5bda1c1c085591e077ea1 237 Pfam PF00181 Ribosomal Proteins L2, RNA binding domain 11 81 1.3E-17 T 31-10-2018 IPR022666 Ribosomal Proteins L2, RNA binding domain GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1922 b439a8c149e5bda1c1c085591e077ea1 237 PIRSF PIRSF002158 1 237 7.9E-74 T 31-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1922 b439a8c149e5bda1c1c085591e077ea1 237 SUPERFAMILY SSF50249 1 88 8.57E-21 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_1922 b439a8c149e5bda1c1c085591e077ea1 237 SMART SM01382 88 221 1.8E-72 T 31-10-2018 IPR022669 Ribosomal protein L2, C-terminal GO:0003735|GO:0005840|GO:0006412 AF_1922 b439a8c149e5bda1c1c085591e077ea1 237 Hamap MF_01320_A 50S ribosomal protein L2 [rplB]. 1 236 43.533 T 31-10-2018 IPR023672 Ribosomal protein L2, archaeal-type GO:0003723|GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1922 b439a8c149e5bda1c1c085591e077ea1 237 Gene3D G3DSA:2.30.30.30 82 159 4.3E-30 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 AF_1922 b439a8c149e5bda1c1c085591e077ea1 237 SMART SM01383 11 82 9.3E-23 T 31-10-2018 IPR002171 Ribosomal protein L2 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1922 b439a8c149e5bda1c1c085591e077ea1 237 SUPERFAMILY SSF50104 91 235 1.08E-53 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily AF_1922 b439a8c149e5bda1c1c085591e077ea1 237 Gene3D G3DSA:2.40.50.140 1 78 4.0E-26 T 31-10-2018 AF_1683 74ed0dbddba818ffc3b3c6e9849d8eca 156 Pfam PF01850 PIN domain 4 125 1.9E-12 T 31-10-2018 IPR002716 PIN domain AF_1683 74ed0dbddba818ffc3b3c6e9849d8eca 156 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 135 11.734 T 31-10-2018 IPR022907 VapC family GO:0004540 AF_1683 74ed0dbddba818ffc3b3c6e9849d8eca 156 SUPERFAMILY SSF88723 1 134 3.36E-21 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_1683 74ed0dbddba818ffc3b3c6e9849d8eca 156 Gene3D G3DSA:3.40.50.1010 1 156 3.9E-53 T 31-10-2018 AF_0409 94a89cc93b2f88a24d848ee1a98c5034 386 Pfam PF00155 Aminotransferase class I and II 32 380 4.1E-63 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AF_0409 94a89cc93b2f88a24d848ee1a98c5034 386 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 236 249 - T 31-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AF_0409 94a89cc93b2f88a24d848ee1a98c5034 386 Gene3D G3DSA:3.90.1150.10 18 380 3.0E-130 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AF_0409 94a89cc93b2f88a24d848ee1a98c5034 386 TIGRFAM TIGR03540 DapC_direct: LL-diaminopimelate aminotransferase 3 382 3.6E-195 T 31-10-2018 IPR019881 Diaminopimelate aminotransferase, DapL, Desulfovibrio-type GO:0009089|GO:0010285 KEGG: 00300+2.6.1.83|MetaCyc: PWY-5097 AF_0409 94a89cc93b2f88a24d848ee1a98c5034 386 SUPERFAMILY SSF53383 1 385 2.89E-112 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AF_0409 94a89cc93b2f88a24d848ee1a98c5034 386 Gene3D G3DSA:3.40.640.10 43 284 3.0E-130 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AF_1174 60530cd606bae2840a1d096c4c625a88 206 SUPERFAMILY SSF55718 1 206 2.83E-29 T 31-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AF_1174 60530cd606bae2840a1d096c4c625a88 206 Pfam PF02036 SCP-2 sterol transfer family 93 192 3.3E-16 T 31-10-2018 IPR003033 SCP2 sterol-binding domain AF_1174 60530cd606bae2840a1d096c4c625a88 206 Gene3D G3DSA:3.30.1050.10 78 202 5.4E-19 T 31-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AF_1174 60530cd606bae2840a1d096c4c625a88 206 Gene3D G3DSA:3.30.1050.10 4 58 1.9E-6 T 31-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AF_0338 a1f24f056d2325046e19970522fbd91d 595 Gene3D G3DSA:3.40.50.300 313 593 4.3E-105 T 31-10-2018 AF_0338 a1f24f056d2325046e19970522fbd91d 595 SUPERFAMILY SSF52540 196 522 4.68E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0338 a1f24f056d2325046e19970522fbd91d 595 Pfam PF00437 Type II/IV secretion system protein 217 461 2.9E-52 T 31-10-2018 IPR001482 Type II/IV secretion system protein AF_0338 a1f24f056d2325046e19970522fbd91d 595 Gene3D G3DSA:3.30.450.380 87 311 8.4E-68 T 31-10-2018 AF_1542 8be2ed8de9b193d96f6d19e8f8c4de5d 101 Gene3D G3DSA:1.10.10.10 1 101 3.2E-24 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1542 8be2ed8de9b193d96f6d19e8f8c4de5d 101 Pfam PF03551 Transcriptional regulator PadR-like family 15 83 5.0E-19 T 31-10-2018 IPR005149 Transcription regulator PadR, N-terminal AF_1542 8be2ed8de9b193d96f6d19e8f8c4de5d 101 SUPERFAMILY SSF46785 3 98 5.09E-30 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1477 e197ae52f5aa73d93562be9bc44d99ba 128 SUPERFAMILY SSF55021 61 125 2.71E-18 T 31-10-2018 AF_1477 e197ae52f5aa73d93562be9bc44d99ba 128 Gene3D G3DSA:3.30.2130.10 1 122 3.3E-28 T 31-10-2018 AF_1477 e197ae52f5aa73d93562be9bc44d99ba 128 PIRSF PIRSF008459 1 128 1.8E-58 T 31-10-2018 IPR016540 Uncharacterised conserved protein UCP008459 AF_1477 e197ae52f5aa73d93562be9bc44d99ba 128 Pfam PF13840 ACT domain 57 119 4.2E-21 T 31-10-2018 IPR027795 CASTOR, ACT domain AF_0917 166ec86363767d7a943a87b5384c8f6c 296 Gene3D G3DSA:1.10.8.240 32 119 2.9E-98 T 31-10-2018 AF_0917 166ec86363767d7a943a87b5384c8f6c 296 Gene3D G3DSA:3.40.50.10680 5 269 2.9E-98 T 31-10-2018 AF_0917 166ec86363767d7a943a87b5384c8f6c 296 Hamap MF_01257 2-phospho-L-lactate transferase [cofD]. 1 296 109.624 T 31-10-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 AF_0917 166ec86363767d7a943a87b5384c8f6c 296 TIGRFAM TIGR01819 F420_cofD: 2-phospho-L-lactate transferase 2 290 1.1E-137 T 31-10-2018 IPR010115 2-phospho-L-lactate transferase GO:0000287|GO:0016780|GO:0051188 KEGG: 00680+2.7.8.28|MetaCyc: PWY-5198 AF_0917 166ec86363767d7a943a87b5384c8f6c 296 SUPERFAMILY SSF142338 2 293 2.75E-86 T 31-10-2018 AF_0917 166ec86363767d7a943a87b5384c8f6c 296 Pfam PF01933 Uncharacterised protein family UPF0052 3 275 5.9E-50 T 31-10-2018 IPR002882 LPPG:FO 2-phospho-L-lactate transferase CofD/UPF0052 AF_2001 1772dcfbcd1d3df6c02da34c9bb463cb 178 SUPERFAMILY SSF52540 1 148 4.35E-18 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2001 1772dcfbcd1d3df6c02da34c9bb463cb 178 Gene3D G3DSA:3.40.50.300 1 178 1.5E-40 T 31-10-2018 AF_2001 1772dcfbcd1d3df6c02da34c9bb463cb 178 Hamap MF_00039 Putative adenylate kinase. 1 155 25.892 T 31-10-2018 IPR020618 Adenylate kinase isoenzyme 6 GO:0004017|GO:0005524 KEGG: 00230+2.7.4.3|KEGG: 00730+2.7.4.3|MetaCyc: PWY-7219|Reactome: R-HSA-499943 AF_2001 1772dcfbcd1d3df6c02da34c9bb463cb 178 Pfam PF13238 AAA domain 3 112 7.8E-19 T 31-10-2018 AF_0395 eec96582480f55cea678f5094bad88d1 436 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 228 242 1.9E-21 T 31-10-2018 AF_0395 eec96582480f55cea678f5094bad88d1 436 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 379 394 1.9E-21 T 31-10-2018 AF_0395 eec96582480f55cea678f5094bad88d1 436 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 269 276 1.9E-21 T 31-10-2018 AF_0395 eec96582480f55cea678f5094bad88d1 436 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 2 24 1.9E-21 T 31-10-2018 AF_0395 eec96582480f55cea678f5094bad88d1 436 PRINTS PR00411 Pyridine nucleotide disulphide reductase class-I signature 145 170 1.9E-21 T 31-10-2018 AF_0395 eec96582480f55cea678f5094bad88d1 436 Gene3D G3DSA:3.50.50.60 109 429 5.6E-153 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0395 eec96582480f55cea678f5094bad88d1 436 Pfam PF02852 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain 322 421 6.6E-24 T 31-10-2018 IPR004099 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain GO:0045454|GO:0055114 AF_0395 eec96582480f55cea678f5094bad88d1 436 Gene3D G3DSA:3.50.50.60 2 332 5.6E-153 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0395 eec96582480f55cea678f5094bad88d1 436 SUPERFAMILY SSF55424 315 432 4.64E-32 T 31-10-2018 IPR016156 FAD/NAD-linked reductase, dimerisation domain superfamily GO:0016491|GO:0050660|GO:0055114 AF_0395 eec96582480f55cea678f5094bad88d1 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 145 163 1.3E-27 T 31-10-2018 AF_0395 eec96582480f55cea678f5094bad88d1 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 227 243 1.3E-27 T 31-10-2018 AF_0395 eec96582480f55cea678f5094bad88d1 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 100 118 1.3E-27 T 31-10-2018 AF_0395 eec96582480f55cea678f5094bad88d1 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 254 276 1.3E-27 T 31-10-2018 AF_0395 eec96582480f55cea678f5094bad88d1 436 PRINTS PR00368 FAD-dependent pyridine nucleotide reductase signature 3 22 1.3E-27 T 31-10-2018 AF_0395 eec96582480f55cea678f5094bad88d1 436 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 2 284 3.6E-63 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AF_0395 eec96582480f55cea678f5094bad88d1 436 SUPERFAMILY SSF51905 1 308 1.13E-51 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1955 d6da942e02cc0acbcf1cbe1f09c46ab8 474 Gene3D G3DSA:1.10.10.2310 16 198 1.3E-33 T 31-10-2018 AF_1955 d6da942e02cc0acbcf1cbe1f09c46ab8 474 Gene3D G3DSA:1.10.10.2320 60 156 1.3E-33 T 31-10-2018 AF_1955 d6da942e02cc0acbcf1cbe1f09c46ab8 474 TIGRFAM TIGR00468 pheS: phenylalanine--tRNA ligase, alpha subunit 149 470 3.8E-135 T 31-10-2018 IPR004529 Phenylalanyl-tRNA synthetase, class IIc, alpha subunit GO:0000166|GO:0004826|GO:0005524|GO:0005737|GO:0006432 KEGG: 00970+6.1.1.20|Reactome: R-HSA-379716 AF_1955 d6da942e02cc0acbcf1cbe1f09c46ab8 474 Gene3D G3DSA:1.10.10.2330 73 126 1.3E-33 T 31-10-2018 AF_1955 d6da942e02cc0acbcf1cbe1f09c46ab8 474 SUPERFAMILY SSF55681 200 470 4.33E-70 T 31-10-2018 AF_1955 d6da942e02cc0acbcf1cbe1f09c46ab8 474 SUPERFAMILY SSF46785 3 71 3.59E-7 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1955 d6da942e02cc0acbcf1cbe1f09c46ab8 474 Hamap MF_00282 Phenylalanine--tRNA ligase alpha subunit [pheS]. 1 470 40.029 T 31-10-2018 IPR022917 Phenylalanine-tRNA ligase alpha subunit, bacterial/archaeal GO:0004826 KEGG: 00970+6.1.1.20 AF_1955 d6da942e02cc0acbcf1cbe1f09c46ab8 474 Pfam PF01409 tRNA synthetases class II core domain (F) 200 468 3.7E-95 T 31-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 AF_1955 d6da942e02cc0acbcf1cbe1f09c46ab8 474 Gene3D G3DSA:3.30.930.10 216 474 1.5E-91 T 31-10-2018 AF_1011 d533a3090208650317d54b0dc9c6be4c 330 Pfam PF01428 AN1-like Zinc finger 66 102 3.1E-13 T 31-10-2018 IPR000058 Zinc finger, AN1-type GO:0008270 AF_1011 d533a3090208650317d54b0dc9c6be4c 330 Pfam PF01694 Rhomboid family 171 322 1.6E-36 T 31-10-2018 IPR022764 Peptidase S54, rhomboid domain GO:0004252|GO:0016021 AF_1011 d533a3090208650317d54b0dc9c6be4c 330 SUPERFAMILY SSF118310 52 106 6.93E-15 T 31-10-2018 IPR035896 AN1-like Zinc finger AF_1011 d533a3090208650317d54b0dc9c6be4c 330 Gene3D G3DSA:4.10.1110.10 49 110 1.3E-12 T 31-10-2018 IPR035896 AN1-like Zinc finger AF_1011 d533a3090208650317d54b0dc9c6be4c 330 Gene3D G3DSA:1.20.1540.10 131 318 8.2E-34 T 31-10-2018 IPR035952 Rhomboid-like superfamily AF_1011 d533a3090208650317d54b0dc9c6be4c 330 SUPERFAMILY SSF144091 136 322 5.23E-37 T 31-10-2018 AF_1011 d533a3090208650317d54b0dc9c6be4c 330 SMART SM00154 66 103 1.3E-18 T 31-10-2018 IPR000058 Zinc finger, AN1-type GO:0008270 AF_0464 b330ae97b1b3537c6a4e1408e183aee7 410 Pfam PF01494 FAD binding domain 25 327 1.1E-14 T 31-10-2018 IPR002938 FAD-binding domain GO:0071949 AF_0464 b330ae97b1b3537c6a4e1408e183aee7 410 Hamap MF_01287 Digeranylgeranylglycerophospholipid reductase. 23 410 45.999 T 31-10-2018 IPR023590 Digeranylgeranylglycerophospholipid reductase GO:0016628|GO:0045550|GO:0046467|GO:0055114 KEGG: 00564+1.3.7.11|MetaCyc: PWY-6349 AF_0464 b330ae97b1b3537c6a4e1408e183aee7 410 Gene3D G3DSA:3.30.9.10 90 382 1.7E-123 T 31-10-2018 AF_0464 b330ae97b1b3537c6a4e1408e183aee7 410 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 25 323 1.9E-73 T 31-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 AF_0464 b330ae97b1b3537c6a4e1408e183aee7 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 289 304 9.1E-14 T 31-10-2018 AF_0464 b330ae97b1b3537c6a4e1408e183aee7 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 167 182 9.1E-14 T 31-10-2018 AF_0464 b330ae97b1b3537c6a4e1408e183aee7 410 PRINTS PR00420 Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature 26 48 9.1E-14 T 31-10-2018 AF_0464 b330ae97b1b3537c6a4e1408e183aee7 410 SUPERFAMILY SSF51905 24 366 2.7E-41 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0464 b330ae97b1b3537c6a4e1408e183aee7 410 Gene3D G3DSA:3.50.50.60 25 363 1.7E-123 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1510 470589b1e933e844e280e305eb211436 552 SUPERFAMILY SSF56801 8 545 7.46E-161 T 31-10-2018 AF_1510 470589b1e933e844e280e305eb211436 552 ProSitePatterns PS00455 Putative AMP-binding domain signature. 198 209 - T 31-10-2018 IPR020845 AMP-binding, conserved site AF_1510 470589b1e933e844e280e305eb211436 552 Pfam PF00501 AMP-binding enzyme 28 447 1.5E-114 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_1510 470589b1e933e844e280e305eb211436 552 Gene3D G3DSA:3.30.300.310 443 549 4.9E-29 T 31-10-2018 AF_1510 470589b1e933e844e280e305eb211436 552 Pfam PF13193 AMP-binding enzyme C-terminal domain 456 533 2.1E-19 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AF_1510 470589b1e933e844e280e305eb211436 552 Gene3D G3DSA:3.40.50.12780 13 442 1.9E-125 T 31-10-2018 AF_1494 a02601d807c21cc39032a7192c66a5ee 235 SUPERFAMILY SSF51182 12 180 7.27E-24 T 31-10-2018 IPR011051 RmlC-like cupin domain superfamily AF_1494 a02601d807c21cc39032a7192c66a5ee 235 Gene3D G3DSA:2.60.120.10 4 192 2.1E-49 T 31-10-2018 IPR014710 RmlC-like jelly roll fold AF_1494 a02601d807c21cc39032a7192c66a5ee 235 Pfam PF06560 Glucose-6-phosphate isomerase (GPI) 14 189 4.5E-81 T 31-10-2018 IPR010551 Glucose-6-phosphate isomerase, prokaryote GO:0004347|GO:0005737|GO:0006094|GO:0006096 KEGG: 00010+5.3.1.9|KEGG: 00030+5.3.1.9|KEGG: 00500+5.3.1.9|KEGG: 00520+5.3.1.9|MetaCyc: PWY-3801|MetaCyc: PWY-5054|MetaCyc: PWY-5384|MetaCyc: PWY-5514|MetaCyc: PWY-5659|MetaCyc: PWY-6142|MetaCyc: PWY-621|MetaCyc: PWY-622|MetaCyc: PWY-6981|MetaCyc: PWY-6992|MetaCyc: PWY-7238|MetaCyc: PWY-7347|MetaCyc: PWY-7385 AF_0600 41a8b05943733efdd1142ab03a3f5dc9 310 SUPERFAMILY SSF52540 4 270 3.38E-15 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1508 6ffd3f99024d023e407946952899a6b4 480 Pfam PF01925 Sulfite exporter TauE/SafE 28 296 4.8E-32 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AF_2152 92d6ad7c69540574b733087aeb1c02de 125 Pfam PF01201 Ribosomal protein S8e 2 124 6.1E-33 T 31-10-2018 IPR022309 Ribosomal protein S8e/ribosomal biogenesis NSA2 AF_2152 92d6ad7c69540574b733087aeb1c02de 125 ProSitePatterns PS01193 Ribosomal protein S8e signature. 9 28 - T 31-10-2018 IPR018283 Ribosomal protein S8e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2152 92d6ad7c69540574b733087aeb1c02de 125 TIGRFAM TIGR00307 eS8: ribosomal protein eS8 1 125 2.6E-61 T 31-10-2018 IPR001047 Ribosomal protein S8e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2152 92d6ad7c69540574b733087aeb1c02de 125 Hamap MF_00029 30S ribosomal protein S8e [rps8e]. 1 125 32.035 T 31-10-2018 IPR020919 Ribosomal protein S8e, archaeal GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_2152 92d6ad7c69540574b733087aeb1c02de 125 Gene3D G3DSA:2.40.10.310 57 125 4.0E-31 T 31-10-2018 AF_1064 722f0dc7f6034732725afd05d88cdfce 620 Gene3D G3DSA:3.40.630.30 185 341 4.0E-6 T 31-10-2018 AF_1064 722f0dc7f6034732725afd05d88cdfce 620 SUPERFAMILY SSF52540 412 618 2.21E-33 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1064 722f0dc7f6034732725afd05d88cdfce 620 Gene3D G3DSA:3.40.50.300 389 620 3.0E-38 T 31-10-2018 AF_1064 722f0dc7f6034732725afd05d88cdfce 620 SMART SM00382 437 615 8.8E-14 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1064 722f0dc7f6034732725afd05d88cdfce 620 SUPERFAMILY SSF55729 269 337 3.09E-6 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase AF_1064 722f0dc7f6034732725afd05d88cdfce 620 Pfam PF00005 ABC transporter 428 563 6.4E-19 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_2069 d54c655de21933793d6eb8be082bc67e 147 ProSitePatterns PS00628 Ribosomal protein S19e signature. 85 104 - T 31-10-2018 IPR018277 Ribosomal protein S19e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2069 d54c655de21933793d6eb8be082bc67e 147 Pfam PF01090 Ribosomal protein S19e 3 135 1.2E-55 T 31-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2069 d54c655de21933793d6eb8be082bc67e 147 Gene3D G3DSA:1.10.10.2700 1 147 1.7E-59 T 31-10-2018 IPR038111 Ribosomal protein S19e domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2069 d54c655de21933793d6eb8be082bc67e 147 SUPERFAMILY SSF46785 3 147 2.31E-53 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_2069 d54c655de21933793d6eb8be082bc67e 147 SMART SM01413 3 136 1.6E-85 T 31-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2069 d54c655de21933793d6eb8be082bc67e 147 Hamap MF_01474 30S ribosomal protein S19e [rps19e]. 1 145 37.499 T 31-10-2018 IPR027548 Ribosomal protein S19e, archaeal GO:0003735|GO:0005840|GO:0006412 AF_2069 d54c655de21933793d6eb8be082bc67e 147 ProDom PD003854 RIBOSOMAL 40S RIBONUCLEOPROTEIN S19 S19E 30S MULTIGENE FAMILY S19 SSU 3 115 4.0E-61 T 31-10-2018 IPR001266 Ribosomal protein S19e GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2391 3977cc223a84731af4e9471fae8bc3c3 66 ProDom PD050957 AF2391 PREDICTED 1 34 2.0E-12 T 31-10-2018 AF_2391 3977cc223a84731af4e9471fae8bc3c3 66 Pfam PF17253 Family of unknown function (DUF5320) 1 58 4.5E-13 T 31-10-2018 IPR035205 Protein of unknown function DUF5320 AF_1796 f79737f93734165617d86dbfc5861fa9 183 Pfam PF01380 SIS domain 31 133 1.3E-19 T 31-10-2018 IPR001347 Sugar isomerase (SIS) GO:0097367|GO:1901135 AF_1796 f79737f93734165617d86dbfc5861fa9 183 SUPERFAMILY SSF53697 1 181 1.5E-42 T 31-10-2018 AF_1796 f79737f93734165617d86dbfc5861fa9 183 Gene3D G3DSA:3.40.50.10490 1 183 3.3E-64 T 31-10-2018 AF_1796 f79737f93734165617d86dbfc5861fa9 183 TIGRFAM TIGR03127 RuMP_HxlB: 6-phospho 3-hexuloisomerase 6 183 5.3E-67 T 31-10-2018 IPR017552 3-hexulose-6-phosphate isomerase GO:0016853 AF_1657 13aebfe4e2600ef42931db1a141ee422 151 TIGRFAM TIGR02228 sigpep_I_arch: signal peptidase I 7 145 1.6E-24 T 31-10-2018 IPR001733 Peptidase S26B GO:0006465|GO:0008233|GO:0016020 AF_1657 13aebfe4e2600ef42931db1a141ee422 151 Pfam PF00717 Peptidase S24-like 30 95 4.9E-7 T 31-10-2018 IPR015927 Peptidase S24/S26A/S26B/S26C AF_1657 13aebfe4e2600ef42931db1a141ee422 151 SUPERFAMILY SSF51306 28 128 1.36E-9 T 31-10-2018 IPR036286 LexA/Signal peptidase-like superfamily AF_0466 590183c7b7829acff0c0dfd7d87c88e4 684 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 122 422 3.4E-55 T 31-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AF_0466 590183c7b7829acff0c0dfd7d87c88e4 684 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 25 681 1.8E-214 T 31-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ AF_0823 cb84eb71250cb28ab433926079ee46d8 248 Gene3D G3DSA:3.40.50.300 1 244 2.5E-66 T 31-10-2018 AF_0823 cb84eb71250cb28ab433926079ee46d8 248 Pfam PF00005 ABC transporter 17 173 2.0E-29 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0823 cb84eb71250cb28ab433926079ee46d8 248 Pfam PF12399 Branched-chain amino acid ATP-binding cassette transporter 221 243 6.5E-10 T 31-10-2018 IPR032823 Branched-chain amino acid ATP-binding cassette transporter, C-terminal AF_0823 cb84eb71250cb28ab433926079ee46d8 248 SUPERFAMILY SSF52540 2 244 4.77E-64 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0823 cb84eb71250cb28ab433926079ee46d8 248 SMART SM00382 26 236 2.0E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0125 849ac42f922da6f6837ca3832ed9fb08 167 Gene3D G3DSA:3.40.50.620 5 147 6.0E-13 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_0125 849ac42f922da6f6837ca3832ed9fb08 167 SUPERFAMILY SSF52402 8 153 9.21E-16 T 31-10-2018 AF_0125 849ac42f922da6f6837ca3832ed9fb08 167 Pfam PF00582 Universal stress protein family 7 146 1.6E-17 T 31-10-2018 IPR006016 UspA AF_1815 29c86ecef2b110d15aad088ca4ec3383 424 PIRSF PIRSF000521 8 149 0.025 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AF_1815 29c86ecef2b110d15aad088ca4ec3383 424 PIRSF PIRSF000521 176 409 7.7E-28 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AF_1815 29c86ecef2b110d15aad088ca4ec3383 424 SUPERFAMILY SSF53383 26 407 8.57E-108 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AF_1815 29c86ecef2b110d15aad088ca4ec3383 424 Pfam PF00202 Aminotransferase class-III 35 404 1.1E-90 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AF_1815 29c86ecef2b110d15aad088ca4ec3383 424 Gene3D G3DSA:3.90.1150.10 9 404 4.8E-133 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AF_1815 29c86ecef2b110d15aad088ca4ec3383 424 Gene3D G3DSA:3.40.640.10 69 312 4.8E-133 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AF_1815 29c86ecef2b110d15aad088ca4ec3383 424 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 227 264 - T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AF_1106 a5907d148c42860f59edd3b277bfe0c4 153 SUPERFAMILY SSF52954 3 82 4.32E-19 T 31-10-2018 AF_1106 a5907d148c42860f59edd3b277bfe0c4 153 Hamap MF_00699 Probable Brix domain-containing ribosomal biogenesis protein. 2 151 27.104 T 31-10-2018 IPR023548 Probable Brix domain-containing ribosomal biogenesis protein AF_1106 a5907d148c42860f59edd3b277bfe0c4 153 SMART SM00879 3 148 1.6E-4 T 31-10-2018 IPR007109 Brix domain AF_1106 a5907d148c42860f59edd3b277bfe0c4 153 Gene3D G3DSA:3.40.50.10480 1 139 4.5E-27 T 31-10-2018 AF_1325 5cdc0cfcd641ad247c5d7de165908bbc 371 Gene3D G3DSA:1.20.1250.20 191 362 3.8E-23 T 31-10-2018 AF_1325 5cdc0cfcd641ad247c5d7de165908bbc 371 Pfam PF07690 Major Facilitator Superfamily 198 354 4.4E-22 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AF_1325 5cdc0cfcd641ad247c5d7de165908bbc 371 Pfam PF07690 Major Facilitator Superfamily 4 185 5.9E-32 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AF_1325 5cdc0cfcd641ad247c5d7de165908bbc 371 Gene3D G3DSA:1.20.1250.20 1 190 3.9E-33 T 31-10-2018 AF_1325 5cdc0cfcd641ad247c5d7de165908bbc 371 SUPERFAMILY SSF103473 2 359 3.27E-55 T 31-10-2018 IPR036259 MFS transporter superfamily AF_0714 af2aca93f3a3d00b24082557ecfa8c21 273 Hamap MF_00058 F420-dependent methylenetetrahydromethanopterin dehydrogenase [mtd]. 1 273 50.96 T 31-10-2018 IPR002844 F420-dependent methylenetetrahydromethanopterin dehydrogenase GO:0008901|GO:0015948|GO:0055114 KEGG: 00680+1.5.98.1|MetaCyc: PWY-5198 AF_0714 af2aca93f3a3d00b24082557ecfa8c21 273 ProDom PD017604 DEHYDROGENASE METHYLENETETRAHYDROMETHANOPTERIN F420-DEPENDENT MTD COENZYME DEPENDENT F420 N5N10- ONE-CARBON METABOLISM 9 273 3.0E-139 T 31-10-2018 IPR002844 F420-dependent methylenetetrahydromethanopterin dehydrogenase GO:0008901|GO:0015948|GO:0055114 KEGG: 00680+1.5.98.1|MetaCyc: PWY-5198 AF_0714 af2aca93f3a3d00b24082557ecfa8c21 273 Pfam PF01993 methylene-5,6,7,8-tetrahydromethanopterin dehydrogenase 3 273 9.6E-136 T 31-10-2018 IPR002844 F420-dependent methylenetetrahydromethanopterin dehydrogenase GO:0008901|GO:0015948|GO:0055114 KEGG: 00680+1.5.98.1|MetaCyc: PWY-5198 AF_0714 af2aca93f3a3d00b24082557ecfa8c21 273 PIRSF PIRSF005627 1 273 1.4E-143 T 31-10-2018 IPR002844 F420-dependent methylenetetrahydromethanopterin dehydrogenase GO:0008901|GO:0015948|GO:0055114 KEGG: 00680+1.5.98.1|MetaCyc: PWY-5198 AF_0714 af2aca93f3a3d00b24082557ecfa8c21 273 SUPERFAMILY SSF102324 1 273 1.05E-126 T 31-10-2018 IPR036080 F420-dependent methylenetetrahydromethanopterin dehydrogenase superfamily GO:0008901|GO:0015948|GO:0055114 KEGG: 00680+1.5.98.1|MetaCyc: PWY-5198 AF_0714 af2aca93f3a3d00b24082557ecfa8c21 273 Gene3D G3DSA:3.40.50.10830 1 131 2.3E-46 T 31-10-2018 AF_0320 21d62e65abf93f3c72ba809b647050bc 93 Pfam PF01850 PIN domain 1 80 8.3E-8 T 31-10-2018 IPR002716 PIN domain AF_0741 d25a4112827152a4b6c3345935396b82 123 Gene3D G3DSA:2.60.120.460 1 121 5.2E-38 T 31-10-2018 IPR035917 YjbQ-like superfamily AF_0741 d25a4112827152a4b6c3345935396b82 123 PIRSF PIRSF004681 1 122 5.7E-39 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 AF_0741 d25a4112827152a4b6c3345935396b82 123 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 1 119 2.2E-28 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 AF_0741 d25a4112827152a4b6c3345935396b82 123 SUPERFAMILY SSF111038 2 119 2.35E-36 T 31-10-2018 IPR035917 YjbQ-like superfamily AF_0741 d25a4112827152a4b6c3345935396b82 123 Pfam PF01894 Uncharacterised protein family UPF0047 3 119 2.2E-32 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 AF_2220 d377acf9a60ebce394e982107acc62fe 88 Gene3D G3DSA:3.50.50.60 1 88 8.6E-17 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_2220 d377acf9a60ebce394e982107acc62fe 88 SUPERFAMILY SSF51905 1 86 4.1E-11 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1850 d0fafe8095e3adca5d98eff1ac178ad1 291 SUPERFAMILY SSF56281 1 266 2.17E-50 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_1850 d0fafe8095e3adca5d98eff1ac178ad1 291 SMART SM00849 21 210 1.6E-38 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_1850 d0fafe8095e3adca5d98eff1ac178ad1 291 Pfam PF00753 Metallo-beta-lactamase superfamily 19 210 1.3E-24 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_1850 d0fafe8095e3adca5d98eff1ac178ad1 291 Gene3D G3DSA:3.60.15.10 5 260 3.7E-64 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_0907 d07e118fe3ab96e58554f17d0e24f684 419 SUPERFAMILY SSF103473 16 416 4.97E-69 T 31-10-2018 IPR036259 MFS transporter superfamily AF_0907 d07e118fe3ab96e58554f17d0e24f684 419 Gene3D G3DSA:1.20.1250.20 216 419 5.5E-29 T 31-10-2018 AF_0907 d07e118fe3ab96e58554f17d0e24f684 419 Gene3D G3DSA:1.20.1250.20 14 205 1.1E-36 T 31-10-2018 AF_0907 d07e118fe3ab96e58554f17d0e24f684 419 PIRSF PIRSF002808 4 419 9.1E-35 T 31-10-2018 IPR000849 Sugar phosphate transporter GO:0016021|GO:0022857|GO:0055085 AF_0907 d07e118fe3ab96e58554f17d0e24f684 419 Pfam PF07690 Major Facilitator Superfamily 29 288 1.1E-35 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AF_2310 b53b1a3fffa1f00b8a5b256fbad67639 261 TIGRFAM TIGR04336 AmmeMemoSam_B: AmmeMemoRadiSam system protein B 2 259 1.1E-90 T 31-10-2018 AF_2310 b53b1a3fffa1f00b8a5b256fbad67639 261 Hamap MF_00055 MEMO1 family protein . 1 260 60.731 T 31-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 AF_2310 b53b1a3fffa1f00b8a5b256fbad67639 261 Pfam PF01875 Memo-like protein 3 258 8.8E-85 T 31-10-2018 IPR002737 MEMO1 family Reactome: R-HSA-6785631 AF_2310 b53b1a3fffa1f00b8a5b256fbad67639 261 SUPERFAMILY SSF53213 59 192 9.94E-5 T 31-10-2018 AF_2310 b53b1a3fffa1f00b8a5b256fbad67639 261 Gene3D G3DSA:3.40.830.10 1 261 1.7E-59 T 31-10-2018 AF_1410 66680b6c85a15f4e1f24ffc98cb9e98c 357 Gene3D G3DSA:3.30.420.10 182 348 1.3E-22 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AF_1410 66680b6c85a15f4e1f24ffc98cb9e98c 357 Pfam PF00665 Integrase core domain 187 303 2.1E-25 T 31-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AF_1410 66680b6c85a15f4e1f24ffc98cb9e98c 357 SUPERFAMILY SSF53098 183 328 1.52E-28 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily AF_1410 66680b6c85a15f4e1f24ffc98cb9e98c 357 SUPERFAMILY SSF46689 60 167 3.23E-15 T 31-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AF_1410 66680b6c85a15f4e1f24ffc98cb9e98c 357 Pfam PF13518 Helix-turn-helix domain 70 116 1.2E-8 T 31-10-2018 AF_0889 6c0d4f0b1ea951e468d08750f478516f 310 SUPERFAMILY SSF81345 47 203 2.48E-6 T 31-10-2018 IPR037294 ABC transporter, BtuC-like AF_0889 6c0d4f0b1ea951e468d08750f478516f 310 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 283 2.5E-34 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AF_1531 69bed08265162aff7cef6691876d327f 195 Gene3D G3DSA:1.10.150.280 88 185 3.4E-43 T 31-10-2018 AF_1531 69bed08265162aff7cef6691876d327f 195 SUPERFAMILY SSF160975 16 195 2.88E-97 T 31-10-2018 AF_1531 69bed08265162aff7cef6691876d327f 195 Gene3D G3DSA:2.40.50.140 16 87 8.5E-33 T 31-10-2018 AF_1531 69bed08265162aff7cef6691876d327f 195 Pfam PF04919 Protein of unknown function (DUF655) 15 194 1.0E-82 T 31-10-2018 IPR007003 Protein of unknown function DUF655 AF_0567 3437c8f68d417a3b19a729530a10cfbc 148 Pfam PF00501 AMP-binding enzyme 35 139 3.0E-6 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_0567 3437c8f68d417a3b19a729530a10cfbc 148 Gene3D G3DSA:3.40.50.980 34 137 1.7E-13 T 31-10-2018 AF_0567 3437c8f68d417a3b19a729530a10cfbc 148 SUPERFAMILY SSF56801 35 142 3.92E-11 T 31-10-2018 AF_0925 a94ffc3e9c2d57a19ccfd9cfbcf7071d 315 Pfam PF01435 Peptidase family M48 114 306 5.5E-13 T 31-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AF_2397 52e9b16d7378cb66619ef7f02c402fac 798 Hamap MF_01137 Acetyl-CoA decarbonylase/synthase complex subunit alpha [cdhA]. 3 788 45.962 T 31-10-2018 IPR004460 Acetyl-CoA decarbonylase/synthase complex subunit alpha GO:0006084|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 AF_2397 52e9b16d7378cb66619ef7f02c402fac 798 Pfam PF03063 Prismane/CO dehydrogenase family 67 681 6.0E-118 T 31-10-2018 IPR004137 Hydroxylamine reductase/Ni-containing CO dehydrogenase GO:0016491|GO:0055114 KEGG: 00910+1.7.99.1 AF_2397 52e9b16d7378cb66619ef7f02c402fac 798 TIGRFAM TIGR00314 cdhA: CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit 4 788 0.0 T 31-10-2018 IPR004460 Acetyl-CoA decarbonylase/synthase complex subunit alpha GO:0006084|GO:0055114 KEGG: 00633+1.2.7.4|KEGG: 00680+1.2.7.4|KEGG: 00720+1.2.7.4|MetaCyc: PWY-5372|MetaCyc: PWY-6780|MetaCyc: PWY-7784 AF_2397 52e9b16d7378cb66619ef7f02c402fac 798 SUPERFAMILY SSF46548 377 476 7.59E-17 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_2397 52e9b16d7378cb66619ef7f02c402fac 798 Gene3D G3DSA:1.10.1060.10 400 479 0.0 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_2397 52e9b16d7378cb66619ef7f02c402fac 798 Gene3D G3DSA:3.40.50.2030 36 764 0.0 T 31-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 AF_2397 52e9b16d7378cb66619ef7f02c402fac 798 Pfam PF12838 4Fe-4S dicluster domain 404 457 1.2E-7 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_2397 52e9b16d7378cb66619ef7f02c402fac 798 SUPERFAMILY SSF56821 14 733 6.53E-166 T 31-10-2018 IPR011254 Prismane-like superfamily GO:0003824|GO:0016491|GO:0055114 AF_2397 52e9b16d7378cb66619ef7f02c402fac 798 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 443 454 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_2397 52e9b16d7378cb66619ef7f02c402fac 798 Gene3D G3DSA:3.40.50.2030 216 490 0.0 T 31-10-2018 IPR016099 Prismane-like, alpha/beta-sandwich GO:0003824|GO:0055114 KEGG: 00910+1.7.99.1 AF_2011 0cadcf3c915fbacbde64cbf0d4ca3d2a 86 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 4 45 1.8E-19 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AF_2011 0cadcf3c915fbacbde64cbf0d4ca3d2a 86 SUPERFAMILY SSF89447 2 62 7.85E-15 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily AF_2011 0cadcf3c915fbacbde64cbf0d4ca3d2a 86 Gene3D G3DSA:2.10.260.10 3 43 2.1E-15 T 31-10-2018 AF_2011 0cadcf3c915fbacbde64cbf0d4ca3d2a 86 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 5 49 7.8E-15 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AF_2011 0cadcf3c915fbacbde64cbf0d4ca3d2a 86 SMART SM00966 5 50 5.2E-17 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AF_0726 b171404cef2165d82fc631971f05f617 234 Gene3D G3DSA:3.30.950.10 109 225 5.8E-27 T 31-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AF_0726 b171404cef2165d82fc631971f05f617 234 SUPERFAMILY SSF53790 2 233 7.98E-62 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AF_0726 b171404cef2165d82fc631971f05f617 234 Gene3D G3DSA:3.40.1010.10 1 108 8.9E-32 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AF_0726 b171404cef2165d82fc631971f05f617 234 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 2 202 4.3E-49 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AF_0705 e2808a809ddcadacdce5712f9f9ec9af 590 SUPERFAMILY SSF54211 32 223 3.79E-25 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AF_0705 e2808a809ddcadacdce5712f9f9ec9af 590 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 42 171 2.3E-12 T 31-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 AF_0705 e2808a809ddcadacdce5712f9f9ec9af 590 Gene3D G3DSA:3.30.230.10 20 232 9.7E-26 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AF_0705 e2808a809ddcadacdce5712f9f9ec9af 590 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 104 123 4.6E-7 T 31-10-2018 AF_0705 e2808a809ddcadacdce5712f9f9ec9af 590 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 134 153 4.6E-7 T 31-10-2018 AF_0705 e2808a809ddcadacdce5712f9f9ec9af 590 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 157 175 4.6E-7 T 31-10-2018 AF_2398 2ceb036a9399988801e4f999fc0f657f 175 Hamap MF_01134 Acetyl-CoA decarbonylase/synthase complex subunit epsilon [cdhB]. 1 174 39.256 T 31-10-2018 IPR003704 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GO:0019385 AF_2398 2ceb036a9399988801e4f999fc0f657f 175 PIRSF PIRSF006035 1 175 5.4E-76 T 31-10-2018 IPR003704 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GO:0019385 AF_2398 2ceb036a9399988801e4f999fc0f657f 175 Gene3D G3DSA:3.40.50.1220 18 175 7.1E-67 T 31-10-2018 AF_2398 2ceb036a9399988801e4f999fc0f657f 175 Pfam PF02552 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit 3 172 3.3E-67 T 31-10-2018 IPR003704 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GO:0019385 AF_2398 2ceb036a9399988801e4f999fc0f657f 175 TIGRFAM TIGR00315 cdhB: CO dehydrogenase/acetyl-CoA synthase complex, epsilon subunit 9 174 1.7E-76 T 31-10-2018 IPR003704 CO dehydrogenase beta subunit/acetyl-CoA synthase epsilon subunit GO:0019385 AF_2398 2ceb036a9399988801e4f999fc0f657f 175 SUPERFAMILY SSF52467 20 173 1.47E-52 T 31-10-2018 IPR029035 DHS-like NAD/FAD-binding domain superfamily AF_1525 123236d8aad414ff68a211b08dca6752 285 Pfam PF01925 Sulfite exporter TauE/SafE 8 272 6.8E-37 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AF_1591 242f18af4ddd8a7bb245ff6648791902 286 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 39 1.5E-6 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 AF_1422 cc4fa40bc80e5c3e2671842bba928cc4 225 TIGRFAM TIGR00035 asp_race: aspartate racemase 1 225 1.2E-102 T 31-10-2018 IPR004380 Aspartate racemase GO:0006520|GO:0016855 AF_1422 cc4fa40bc80e5c3e2671842bba928cc4 225 Gene3D G3DSA:3.40.50.1860 102 209 1.4E-81 T 31-10-2018 AF_1422 cc4fa40bc80e5c3e2671842bba928cc4 225 SUPERFAMILY SSF53681 102 205 4.09E-30 T 31-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AF_1422 cc4fa40bc80e5c3e2671842bba928cc4 225 Gene3D G3DSA:3.40.50.1860 2 218 1.4E-81 T 31-10-2018 AF_1422 cc4fa40bc80e5c3e2671842bba928cc4 225 SUPERFAMILY SSF53681 1 114 7.85E-33 T 31-10-2018 IPR001920 Asp/Glu racemase GO:0016855 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AF_1422 cc4fa40bc80e5c3e2671842bba928cc4 225 ProSitePatterns PS00924 Aspartate and glutamate racemases signature 2. 191 201 - T 31-10-2018 IPR033134 Asp/Glu racemase, active site 2 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AF_1422 cc4fa40bc80e5c3e2671842bba928cc4 225 ProSitePatterns PS00923 Aspartate and glutamate racemases signature 1. 77 86 - T 31-10-2018 IPR018187 Asp/Glu racemase, active site 1 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AF_1422 cc4fa40bc80e5c3e2671842bba928cc4 225 Pfam PF01177 Asp/Glu/Hydantoin racemase 5 218 2.3E-58 T 31-10-2018 IPR015942 Asp/Glu/hydantoin racemase GO:0006807|GO:0036361 KEGG: 00471+5.1.1.3|MetaCyc: PWY-6386|MetaCyc: PWY-6387 AF_0088 d3b8c70b2a7c0e3b8143b8a55ea4de84 300 Gene3D G3DSA:3.40.190.10 19 123 6.4E-18 T 31-10-2018 AF_0088 d3b8c70b2a7c0e3b8143b8a55ea4de84 300 SMART SM00062 24 245 1.2E-28 T 31-10-2018 IPR001638 Solute-binding protein family 3/N-terminal domain of MltF AF_0088 d3b8c70b2a7c0e3b8143b8a55ea4de84 300 SUPERFAMILY SSF53850 22 241 1.68E-40 T 31-10-2018 AF_0088 d3b8c70b2a7c0e3b8143b8a55ea4de84 300 Gene3D G3DSA:3.40.190.10 134 300 8.7E-19 T 31-10-2018 AF_0088 d3b8c70b2a7c0e3b8143b8a55ea4de84 300 Pfam PF03180 NLPA lipoprotein 25 248 4.1E-40 T 31-10-2018 IPR004872 Lipoprotein NlpA family AF_1150 26df6dc39bebf9a4308fc255dea48b4c 116 Pfam PF01920 Prefoldin subunit 9 112 3.0E-28 T 31-10-2018 IPR002777 Prefoldin beta-like GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 AF_1150 26df6dc39bebf9a4308fc255dea48b4c 116 Hamap MF_00307 Prefoldin subunit beta [pfdB]. 1 116 52.677 T 31-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 AF_1150 26df6dc39bebf9a4308fc255dea48b4c 116 Gene3D G3DSA:1.10.287.370 1 116 5.4E-41 T 31-10-2018 IPR009053 Prefoldin AF_1150 26df6dc39bebf9a4308fc255dea48b4c 116 SUPERFAMILY SSF46579 6 111 6.28E-26 T 31-10-2018 AF_1150 26df6dc39bebf9a4308fc255dea48b4c 116 TIGRFAM TIGR02338 gimC_beta: prefoldin, beta subunit 4 112 5.7E-44 T 31-10-2018 IPR012713 Prefoldin subunit beta GO:0006457|GO:0016272|GO:0051082 AF_0362 b5e93c9f498b8756e722b852ea774693 75 PIRSF PIRSF006609 1 75 4.8E-27 T 31-10-2018 IPR016487 Sm-like protein Lsm6/SmF GO:0000398|GO:0005732 Reactome: R-HSA-72163 AF_0362 b5e93c9f498b8756e722b852ea774693 75 SUPERFAMILY SSF50182 3 74 2.77E-18 T 31-10-2018 IPR010920 LSM domain superfamily AF_0362 b5e93c9f498b8756e722b852ea774693 75 Pfam PF01423 LSM domain 8 72 5.3E-20 T 31-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type AF_0362 b5e93c9f498b8756e722b852ea774693 75 SMART SM00651 6 72 1.0E-20 T 31-10-2018 IPR001163 LSM domain, eukaryotic/archaea-type AF_0362 b5e93c9f498b8756e722b852ea774693 75 Gene3D G3DSA:2.30.30.100 1 75 4.5E-24 T 31-10-2018 AF_0504 bf5faa204b65212165247f3516fb09cb 301 Hamap MF_01406 UPF0282 protein . 15 297 41.865 T 31-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase AF_0504 bf5faa204b65212165247f3516fb09cb 301 SUPERFAMILY SSF56281 29 274 2.88E-17 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_0504 bf5faa204b65212165247f3516fb09cb 301 PIRSF PIRSF004944 15 301 1.6E-124 T 31-10-2018 IPR014426 Uncharacterised protein family UPF0282, hydrolase, metallo-beta-lactamase AF_0504 bf5faa204b65212165247f3516fb09cb 301 Gene3D G3DSA:3.60.15.10 15 281 2.4E-14 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_1518 9b2393512e0fc4594881d962210fd1e5 192 TIGRFAM TIGR02699 archaeo_AfpA: archaeoflavoprotein AfpA 11 185 5.6E-93 T 31-10-2018 IPR014072 Archaeoflavoprotein AfpA AF_1518 9b2393512e0fc4594881d962210fd1e5 192 SUPERFAMILY SSF52507 7 138 6.54E-26 T 31-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AF_1518 9b2393512e0fc4594881d962210fd1e5 192 Pfam PF02441 Flavoprotein 10 134 1.2E-17 T 31-10-2018 IPR003382 Flavoprotein GO:0003824 Reactome: R-HSA-196783 AF_1518 9b2393512e0fc4594881d962210fd1e5 192 Gene3D G3DSA:3.40.50.1950 6 191 4.0E-44 T 31-10-2018 IPR036551 Flavin prenyltransferase-like GO:0003824 Reactome: R-HSA-196783 AF_1128 a5522d9b693d1b099183b1f360e855c0 156 SUPERFAMILY SSF52161 14 153 9.55E-42 T 31-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 AF_1128 a5522d9b693d1b099183b1f360e855c0 156 TIGRFAM TIGR01077 L13_A_E: ribosomal protein uL13 17 154 1.5E-65 T 31-10-2018 IPR005755 Ribosomal protein L13, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 AF_1128 a5522d9b693d1b099183b1f360e855c0 156 Pfam PF00572 Ribosomal protein L13 16 115 3.6E-12 T 31-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AF_1128 a5522d9b693d1b099183b1f360e855c0 156 Hamap MF_01366 50S ribosomal protein L13 [rplM]. 16 145 21.693 T 31-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AF_1128 a5522d9b693d1b099183b1f360e855c0 156 ProSitePatterns PS00783 Ribosomal protein L13 signature. 91 114 - T 31-10-2018 IPR023563 Ribosomal protein L13, conserved site GO:0003735|GO:0005840|GO:0006412 AF_1128 a5522d9b693d1b099183b1f360e855c0 156 Gene3D G3DSA:3.90.1180.10 9 155 5.2E-53 T 31-10-2018 IPR036899 Ribosomal protein L13 superfamily GO:0003735|GO:0005840|GO:0006412 AF_1128 a5522d9b693d1b099183b1f360e855c0 156 PIRSF PIRSF002181 1 156 7.4E-45 T 31-10-2018 IPR005822 Ribosomal protein L13 GO:0003735|GO:0005840|GO:0006412 AF_0411 85b042723574f7a8e0235911e099046a 467 Gene3D G3DSA:3.40.50.620 1 307 1.0E-130 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_0411 85b042723574f7a8e0235911e099046a 467 Hamap MF_00041 Cysteine--tRNA ligase [cysS]. 1 467 36.964 T 31-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 AF_0411 85b042723574f7a8e0235911e099046a 467 TIGRFAM TIGR00435 cysS: cysteine--tRNA ligase 1 465 3.2E-189 T 31-10-2018 IPR015803 Cysteine-tRNA ligase GO:0004817|GO:0005524|GO:0006423 KEGG: 00970+6.1.1.16 AF_0411 85b042723574f7a8e0235911e099046a 467 Pfam PF09190 DALR domain 355 411 4.3E-13 T 31-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 AF_0411 85b042723574f7a8e0235911e099046a 467 SMART SM00840 355 417 4.1E-17 T 31-10-2018 IPR015273 Cysteinyl-tRNA synthetase, class Ia, DALR GO:0000166|GO:0004817|GO:0005524|GO:0005737|GO:0006423 KEGG: 00970+6.1.1.16 AF_0411 85b042723574f7a8e0235911e099046a 467 Pfam PF01406 tRNA synthetases class I (C) catalytic domain 18 315 1.1E-138 T 31-10-2018 IPR032678 tRNA synthetases class I, catalytic domain KEGG: 00970+6.1.1.16 AF_0411 85b042723574f7a8e0235911e099046a 467 SUPERFAMILY SSF52374 2 315 1.54E-94 T 31-10-2018 AF_0411 85b042723574f7a8e0235911e099046a 467 Gene3D G3DSA:1.20.120.640 308 466 2.4E-30 T 31-10-2018 AF_0411 85b042723574f7a8e0235911e099046a 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 193 211 1.5E-27 T 31-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AF_0411 85b042723574f7a8e0235911e099046a 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 25 36 1.5E-27 T 31-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AF_0411 85b042723574f7a8e0235911e099046a 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 224 245 1.5E-27 T 31-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AF_0411 85b042723574f7a8e0235911e099046a 467 PRINTS PR00983 Cysteinyl-tRNA synthetase signature 61 70 1.5E-27 T 31-10-2018 IPR024909 Cysteinyl-tRNA synthetase/mycothiol ligase KEGG: 00970+6.1.1.16 AF_0411 85b042723574f7a8e0235911e099046a 467 SUPERFAMILY SSF47323 346 466 4.58E-28 T 31-10-2018 IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_1461 02fd176b394d2e5af4661b68d73cca9c 77 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 47 58 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1461 02fd176b394d2e5af4661b68d73cca9c 77 Gene3D G3DSA:3.30.70.20 12 67 5.0E-15 T 31-10-2018 AF_1461 02fd176b394d2e5af4661b68d73cca9c 77 Pfam PF13187 4Fe-4S dicluster domain 17 62 2.0E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1461 02fd176b394d2e5af4661b68d73cca9c 77 SUPERFAMILY SSF54862 11 68 6.28E-17 T 31-10-2018 AF_1461 02fd176b394d2e5af4661b68d73cca9c 77 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 17 28 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_2241 d242195dc30dabe1769bdaa4c2e9438a 131 SUPERFAMILY SSF50891 8 130 2.69E-37 T 31-10-2018 IPR029000 Cyclophilin-like domain superfamily AF_2241 d242195dc30dabe1769bdaa4c2e9438a 131 PIRSF PIRSF006456 5 131 1.6E-71 T 31-10-2018 IPR007256 Protein of unknown function DUF369 AF_2241 d242195dc30dabe1769bdaa4c2e9438a 131 Pfam PF04126 Cyclophilin-like 8 129 2.7E-52 T 31-10-2018 IPR025658 Cyclophilin TM1367-like domain AF_2241 d242195dc30dabe1769bdaa4c2e9438a 131 Gene3D G3DSA:2.40.100.20 5 131 1.3E-50 T 31-10-2018 AF_1378 71742b8843548b2b8115e195f639fb17 168 TIGRFAM TIGR00072 hydrog_prot: hydrogenase maturation protease 5 144 1.2E-39 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AF_1378 71742b8843548b2b8115e195f639fb17 168 Gene3D G3DSA:3.40.50.1450 2 152 1.6E-40 T 31-10-2018 IPR023430 Peptidase HybD-like domain superfamily AF_1378 71742b8843548b2b8115e195f639fb17 168 PRINTS PR00446 Hydrogen uptake protein signature 16 27 1.5E-22 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AF_1378 71742b8843548b2b8115e195f639fb17 168 PRINTS PR00446 Hydrogen uptake protein signature 35 52 1.5E-22 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AF_1378 71742b8843548b2b8115e195f639fb17 168 PRINTS PR00446 Hydrogen uptake protein signature 56 66 1.5E-22 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AF_1378 71742b8843548b2b8115e195f639fb17 168 PRINTS PR00446 Hydrogen uptake protein signature 67 83 1.5E-22 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AF_1378 71742b8843548b2b8115e195f639fb17 168 PRINTS PR00446 Hydrogen uptake protein signature 4 16 1.5E-22 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AF_1378 71742b8843548b2b8115e195f639fb17 168 Pfam PF01750 Hydrogenase maturation protease 21 144 1.1E-33 T 31-10-2018 IPR000671 Peptidase A31 family GO:0008047|GO:0008233 AF_1378 71742b8843548b2b8115e195f639fb17 168 SUPERFAMILY SSF53163 3 146 2.75E-38 T 31-10-2018 IPR023430 Peptidase HybD-like domain superfamily AF_0139 912fa875119eed04bdaa1a43468fb87f 172 Pfam PF01047 MarR family 107 157 3.3E-6 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AF_0139 912fa875119eed04bdaa1a43468fb87f 172 Gene3D G3DSA:1.10.10.10 84 168 3.3E-10 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0139 912fa875119eed04bdaa1a43468fb87f 172 SUPERFAMILY SSF46785 99 163 6.27E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_2102 362b27df94ac45da288929915e0d843f 217 SUPERFAMILY SSF103473 2 215 1.24E-29 T 31-10-2018 IPR036259 MFS transporter superfamily AF_2102 362b27df94ac45da288929915e0d843f 217 Gene3D G3DSA:1.20.1250.20 36 217 3.8E-24 T 31-10-2018 AF_2102 362b27df94ac45da288929915e0d843f 217 Pfam PF07690 Major Facilitator Superfamily 3 183 5.4E-14 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AF_2299 518d648cdf9f8307abe81770168196a0 344 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 217 239 - T 31-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AF_2299 518d648cdf9f8307abe81770168196a0 344 Pfam PF01066 CDP-alcohol phosphatidyltransferase 172 239 2.3E-10 T 31-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AF_2299 518d648cdf9f8307abe81770168196a0 344 Gene3D G3DSA:1.20.120.1760 142 344 4.5E-84 T 31-10-2018 AF_2299 518d648cdf9f8307abe81770168196a0 344 Gene3D G3DSA:3.90.550.30 1 135 1.9E-80 T 31-10-2018 AF_0783 257e6c1c227a3b737661be99afdb7ac1 193 Gene3D G3DSA:2.20.25.420 2 43 5.2E-6 T 31-10-2018 AF_0783 257e6c1c227a3b737661be99afdb7ac1 193 Pfam PF03367 ZPR1 zinc-finger domain 3 154 7.8E-34 T 31-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 AF_0783 257e6c1c227a3b737661be99afdb7ac1 193 Gene3D G3DSA:2.60.120.1040 47 176 8.4E-18 T 31-10-2018 AF_0783 257e6c1c227a3b737661be99afdb7ac1 193 TIGRFAM TIGR00310 ZPR1_znf: ZPR1 zinc finger domain 2 190 2.3E-90 T 31-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 AF_0783 257e6c1c227a3b737661be99afdb7ac1 193 TIGRFAM TIGR00340 zpr1_rel: zinc finger protein ZPR1 homolog 4 164 2.8E-71 T 31-10-2018 IPR004470 Zinc finger, ZPR1-type, subgroup GO:0008270 AF_0783 257e6c1c227a3b737661be99afdb7ac1 193 SMART SM00709 2 156 6.5E-74 T 31-10-2018 IPR004457 Zinc finger, ZPR1-type GO:0008270 AF_1124 ba1d842918c7ed54d34396087056454a 159 Pfam PF01575 MaoC like domain 32 143 1.2E-30 T 31-10-2018 IPR002539 MaoC-like dehydratase domain AF_1124 ba1d842918c7ed54d34396087056454a 159 SUPERFAMILY SSF54637 9 158 6.77E-34 T 31-10-2018 IPR029069 HotDog domain superfamily AF_1124 ba1d842918c7ed54d34396087056454a 159 Gene3D G3DSA:3.10.129.10 1 159 2.3E-53 T 31-10-2018 AF_1124 ba1d842918c7ed54d34396087056454a 159 PRINTS PR01483 Fatty acid synthase signature 50 72 2.6E-5 T 31-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 AF_1124 ba1d842918c7ed54d34396087056454a 159 PRINTS PR01483 Fatty acid synthase signature 72 93 2.6E-5 T 31-10-2018 IPR003965 Fatty acid synthase GO:0004312|GO:0005835|GO:0006633|GO:0055114 AF_2008 6bc2da863d06bfdb37c30f360ac2fb5b 106 Gene3D G3DSA:1.10.10.10 1 106 9.2E-50 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_2008 6bc2da863d06bfdb37c30f360ac2fb5b 106 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 12 82 4.5E-11 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal AF_2008 6bc2da863d06bfdb37c30f360ac2fb5b 106 SUPERFAMILY SSF46785 5 105 9.11E-22 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_2240 48f339ffa1966dc6f835fc55e1c0b999 63 Gene3D G3DSA:1.20.1260.10 1 57 7.6E-10 T 31-10-2018 IPR012347 Ferritin-like AF_2240 48f339ffa1966dc6f835fc55e1c0b999 63 Pfam PF02915 Rubrerythrin 5 58 2.3E-7 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 AF_2240 48f339ffa1966dc6f835fc55e1c0b999 63 SUPERFAMILY SSF47240 1 55 4.92E-10 T 31-10-2018 IPR009078 Ferritin-like superfamily AF_1330 d94accfe4101c8c105df64eda8f6f1a8 336 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 8 331 3.4E-108 T 31-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme AF_1330 d94accfe4101c8c105df64eda8f6f1a8 336 SMART SM00729 72 276 0.0044 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AF_1330 d94accfe4101c8c105df64eda8f6f1a8 336 Pfam PF04055 Radical SAM superfamily 81 232 1.4E-21 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_1330 d94accfe4101c8c105df64eda8f6f1a8 336 Gene3D G3DSA:3.20.20.70 67 283 1.5E-36 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1330 d94accfe4101c8c105df64eda8f6f1a8 336 PIRSF PIRSF004869 3 310 3.7E-99 T 31-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted AF_1330 d94accfe4101c8c105df64eda8f6f1a8 336 SUPERFAMILY SSF102114 50 311 2.62E-38 T 31-10-2018 AF_1924 63d562beb98340f247a5874d91e56937 252 Gene3D G3DSA:3.40.1370.10 2 251 1.0E-97 T 31-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 AF_1924 63d562beb98340f247a5874d91e56937 252 ProSitePatterns PS00939 Ribosomal protein L1e signature. 105 131 - T 31-10-2018 IPR013000 Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1924 63d562beb98340f247a5874d91e56937 252 TIGRFAM TIGR03672 rpl4p_arch: 50S ribosomal protein uL4 1 249 3.3E-116 T 31-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 AF_1924 63d562beb98340f247a5874d91e56937 252 SUPERFAMILY SSF52166 1 249 3.01E-73 T 31-10-2018 IPR023574 Ribosomal protein L4 domain superfamily GO:0003735|GO:0005840|GO:0006412 AF_1924 63d562beb98340f247a5874d91e56937 252 Hamap MF_01328_A 50S ribosomal protein L4 [rplD]. 2 250 43.792 T 31-10-2018 IPR019970 Ribosomal protein L4 GO:0003735|GO:0005840|GO:0006412|GO:0019843 AF_1924 63d562beb98340f247a5874d91e56937 252 Pfam PF00573 Ribosomal protein L4/L1 family 16 249 7.0E-54 T 31-10-2018 IPR002136 Ribosomal protein L4/L1e GO:0003735|GO:0005840|GO:0006412 AF_0708 4e49233cb7b43a4e5b78e0dfa9bdb299 154 Pfam PF14810 Patch-forming domain C2 of tRNA-guanine transglycosylase 8 77 2.2E-27 T 31-10-2018 IPR029402 tRNA-guanine transglycosylase, patch-forming domain C2 MetaCyc: PWY-6711|MetaCyc: PWY-7923 AF_0708 4e49233cb7b43a4e5b78e0dfa9bdb299 154 TIGRFAM TIGR00451 unchar_dom_2: uncharacterized domain 2 59 150 2.3E-13 T 31-10-2018 IPR004521 Uncharacterised domain CHP00451 GO:0003723 AF_0708 4e49233cb7b43a4e5b78e0dfa9bdb299 154 SUPERFAMILY SSF88697 77 152 3.7E-22 T 31-10-2018 IPR015947 PUA-like superfamily AF_0708 4e49233cb7b43a4e5b78e0dfa9bdb299 154 Gene3D G3DSA:2.30.130.10 76 153 2.3E-32 T 31-10-2018 IPR036974 PUA domain superfamily GO:0003723 AF_0708 4e49233cb7b43a4e5b78e0dfa9bdb299 154 SUPERFAMILY SSF88802 1 76 2.42E-20 T 31-10-2018 AF_0708 4e49233cb7b43a4e5b78e0dfa9bdb299 154 Pfam PF01472 PUA domain 80 150 1.9E-19 T 31-10-2018 IPR002478 PUA domain GO:0003723 AF_0708 4e49233cb7b43a4e5b78e0dfa9bdb299 154 Gene3D G3DSA:3.10.450.90 1 75 3.7E-26 T 31-10-2018 IPR038250 TGT, patch-forming C2 domain superfamily MetaCyc: PWY-6711|MetaCyc: PWY-7923 AF_0708 4e49233cb7b43a4e5b78e0dfa9bdb299 154 SMART SM00359 79 153 2.4E-21 T 31-10-2018 IPR002478 PUA domain GO:0003723 AF_1072 d79d37893eaf19488b19b123a0bb375f 69 Pfam PF15919 HicB_like antitoxin of bacterial toxin-antitoxin system 3 57 1.1E-12 T 31-10-2018 IPR031807 HicB-like antitoxin of toxin-antitoxin system AF_1072 d79d37893eaf19488b19b123a0bb375f 69 SUPERFAMILY SSF143100 1 58 9.42E-20 T 31-10-2018 IPR035069 TTHA1013/TTHA0281-like AF_1072 d79d37893eaf19488b19b123a0bb375f 69 Gene3D G3DSA:3.30.160.250 1 65 5.3E-27 T 31-10-2018 AF_1356 63da11f720ec770fc8c52a41fd9d81f5 327 Gene3D G3DSA:3.40.190.10 43 303 4.7E-96 T 31-10-2018 AF_1356 63da11f720ec770fc8c52a41fd9d81f5 327 TIGRFAM TIGR02136 ptsS_2: phosphate binding protein 11 305 8.2E-87 T 31-10-2018 IPR011862 Phosphate binding protein GO:0042301 AF_1356 63da11f720ec770fc8c52a41fd9d81f5 327 Gene3D G3DSA:3.40.190.10 123 266 4.7E-96 T 31-10-2018 AF_1356 63da11f720ec770fc8c52a41fd9d81f5 327 Pfam PF12849 PBP superfamily domain 38 289 1.3E-30 T 31-10-2018 IPR024370 PBP domain AF_1356 63da11f720ec770fc8c52a41fd9d81f5 327 SUPERFAMILY SSF53850 41 320 3.93E-78 T 31-10-2018 AF_0436 ba7f016f18c725d0d2549750f12b2e3c 382 Gene3D G3DSA:1.20.140.10 236 381 7.2E-58 T 31-10-2018 AF_0436 ba7f016f18c725d0d2549750f12b2e3c 382 SUPERFAMILY SSF47203 228 381 7.57E-62 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AF_0436 ba7f016f18c725d0d2549750f12b2e3c 382 SUPERFAMILY SSF56645 1 242 1.44E-75 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AF_0436 ba7f016f18c725d0d2549750f12b2e3c 382 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 113 8.0E-29 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AF_0436 ba7f016f18c725d0d2549750f12b2e3c 382 Gene3D G3DSA:2.40.110.10 121 235 9.4E-42 T 31-10-2018 AF_0436 ba7f016f18c725d0d2549750f12b2e3c 382 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 122 218 5.0E-27 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AF_0436 ba7f016f18c725d0d2549750f12b2e3c 382 Gene3D G3DSA:1.10.540.10 1 119 1.7E-37 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AF_0436 ba7f016f18c725d0d2549750f12b2e3c 382 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 230 378 7.3E-56 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AF_0436 ba7f016f18c725d0d2549750f12b2e3c 382 PIRSF PIRSF016578 4 381 2.1E-21 T 31-10-2018 AF_0436 ba7f016f18c725d0d2549750f12b2e3c 382 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 337 356 - T 31-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AF_1139 369e4e19a433d62b569c3e06477a3c8c 232 Pfam PF00005 ABC transporter 8 144 4.6E-25 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_1139 369e4e19a433d62b569c3e06477a3c8c 232 ProSitePatterns PS00211 ABC transporters family signature. 116 130 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_1139 369e4e19a433d62b569c3e06477a3c8c 232 SUPERFAMILY SSF52540 8 208 1.36E-53 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1139 369e4e19a433d62b569c3e06477a3c8c 232 SMART SM00382 10 192 1.6E-13 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1139 369e4e19a433d62b569c3e06477a3c8c 232 Gene3D G3DSA:3.40.50.300 1 222 3.3E-59 T 31-10-2018 AF_2206 4b53e9bab63836ac642f35a622f01648 148 Pfam PF01467 Cytidylyltransferase-like 5 138 1.4E-21 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AF_2206 4b53e9bab63836ac642f35a622f01648 148 Hamap MF_00647 Phosphopantetheine adenylyltransferase [coaD]. 1 148 33.411 T 31-10-2018 IPR023540 Phosphopantetheine adenylyltransferase, archaea GO:0004595 KEGG: 00770+2.7.7.3|MetaCyc: PWY-7851 AF_2206 4b53e9bab63836ac642f35a622f01648 148 SUPERFAMILY SSF52374 2 138 6.44E-16 T 31-10-2018 AF_2206 4b53e9bab63836ac642f35a622f01648 148 Gene3D G3DSA:3.40.50.620 1 148 8.5E-41 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_2206 4b53e9bab63836ac642f35a622f01648 148 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 3 44 1.2E-8 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AF_0089 21720a5d2a60528c4f29e7e936f4ba07 542 Pfam PF13193 AMP-binding enzyme C-terminal domain 451 528 3.8E-22 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AF_0089 21720a5d2a60528c4f29e7e936f4ba07 542 ProSitePatterns PS00455 Putative AMP-binding domain signature. 183 194 - T 31-10-2018 IPR020845 AMP-binding, conserved site AF_0089 21720a5d2a60528c4f29e7e936f4ba07 542 Gene3D G3DSA:3.40.50.12780 1 435 1.6E-176 T 31-10-2018 AF_0089 21720a5d2a60528c4f29e7e936f4ba07 542 Gene3D G3DSA:3.30.300.310 438 541 2.5E-30 T 31-10-2018 AF_0089 21720a5d2a60528c4f29e7e936f4ba07 542 Pfam PF00501 AMP-binding enzyme 25 442 6.3E-92 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_0089 21720a5d2a60528c4f29e7e936f4ba07 542 SUPERFAMILY SSF56801 17 540 5.49E-140 T 31-10-2018 AF_0228 bd0183e03f4c61f1cb25ba857b3a719f 196 SUPERFAMILY SSF51569 14 195 1.46E-43 T 31-10-2018 AF_0228 bd0183e03f4c61f1cb25ba857b3a719f 196 Pfam PF01487 Type I 3-dehydroquinase 13 191 3.2E-34 T 31-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AF_0228 bd0183e03f4c61f1cb25ba857b3a719f 196 Gene3D G3DSA:3.20.20.70 1 196 5.6E-74 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0228 bd0183e03f4c61f1cb25ba857b3a719f 196 Hamap MF_00214 3-dehydroquinate dehydratase [aroD]. 2 195 34.831 T 31-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AF_0228 bd0183e03f4c61f1cb25ba857b3a719f 196 TIGRFAM TIGR01093 aroD: 3-dehydroquinate dehydratase, type I 8 191 4.3E-55 T 31-10-2018 IPR001381 3-dehydroquinate dehydratase type I GO:0003855 KEGG: 00400+4.2.1.10|MetaCyc: PWY-6163|MetaCyc: PWY-6416|MetaCyc: PWY-6707 AF_1956 d3e74f2218ab456e9681507a5b20ed03 89 PIRSF PIRSF028732 1 89 7.9E-42 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 AF_1956 d3e74f2218ab456e9681507a5b20ed03 89 ProDom PD010497 ALBA DNA-BINDING DNA/RNA-BINDING RNA-BINDING ACETYLATION 3D-STRUCTURE DNA CONDENSATION AF1 SSO10B 7 89 3.0E-41 T 31-10-2018 AF_1956 d3e74f2218ab456e9681507a5b20ed03 89 Hamap MF_01122 DNA/RNA-binding protein Alba [albA]. 1 89 28.314 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 AF_1956 d3e74f2218ab456e9681507a5b20ed03 89 TIGRFAM TIGR00285 TIGR00285: DNA-binding protein Alba 3 89 7.1E-51 T 31-10-2018 IPR013795 DNA/RNA-binding protein Alba GO:0003677|GO:0003723|GO:0005737 AF_1956 d3e74f2218ab456e9681507a5b20ed03 89 SUPERFAMILY SSF82704 4 89 4.06E-29 T 31-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 AF_1956 d3e74f2218ab456e9681507a5b20ed03 89 Pfam PF01918 Alba 5 66 8.2E-24 T 31-10-2018 IPR002775 DNA/RNA-binding protein Alba-like GO:0003676 AF_1956 d3e74f2218ab456e9681507a5b20ed03 89 Gene3D G3DSA:3.30.110.20 1 89 1.7E-40 T 31-10-2018 IPR036882 Alba-like domain superfamily GO:0003676 AF_0722 1956a642f8a8a31314519f3060de9c0b 197 SUPERFAMILY SSF53790 1 182 1.44E-37 T 31-10-2018 IPR035996 Tetrapyrrole methylase superfamily GO:0008168 Reactome: R-HSA-5358493 AF_0722 1956a642f8a8a31314519f3060de9c0b 197 Gene3D G3DSA:3.40.1010.10 1 102 7.6E-25 T 31-10-2018 IPR014777 Tetrapyrrole methylase, subdomain 1 GO:0008168 Reactome: R-HSA-5358493 AF_0722 1956a642f8a8a31314519f3060de9c0b 197 Pfam PF00590 Tetrapyrrole (Corrin/Porphyrin) Methylases 1 178 3.6E-24 T 31-10-2018 IPR000878 Tetrapyrrole methylase GO:0008168 Reactome: R-HSA-5358493 AF_0722 1956a642f8a8a31314519f3060de9c0b 197 TIGRFAM TIGR02467 CbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit 4 182 6.9E-32 T 31-10-2018 IPR012818 Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase GO:0008276|GO:0009236 AF_0722 1956a642f8a8a31314519f3060de9c0b 197 Gene3D G3DSA:3.30.950.10 103 197 2.3E-48 T 31-10-2018 IPR014776 Tetrapyrrole methylase, subdomain 2 GO:0008168 Reactome: R-HSA-5358493 AF_2408 d95db456cae6c1d401767cb206e38060 150 Gene3D G3DSA:1.20.1290.10 5 149 8.7E-25 T 31-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AF_2408 d95db456cae6c1d401767cb206e38060 150 TIGRFAM TIGR00778 ahpD_dom: alkylhydroperoxidase AhpD family core domain 49 98 5.4E-18 T 31-10-2018 IPR004675 Alkylhydroperoxidase AhpD core GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AF_2408 d95db456cae6c1d401767cb206e38060 150 SUPERFAMILY SSF69118 10 148 3.01E-30 T 31-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AF_2408 d95db456cae6c1d401767cb206e38060 150 Pfam PF02627 Carboxymuconolactone decarboxylase family 32 101 1.5E-10 T 31-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AF_2030 7751e60fd708541da8276d7aacd97d13 201 Gene3D G3DSA:3.40.920.10 1 200 3.1E-55 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AF_2030 7751e60fd708541da8276d7aacd97d13 201 TIGRFAM TIGR03334 IOR_beta: indolepyruvate ferredoxin oxidoreductase, beta subunit 3 190 6.2E-68 T 31-10-2018 IPR017719 Indolepyruvate ferredoxin oxidoreductase, beta subunit GO:0043805|GO:0055114 AF_2030 7751e60fd708541da8276d7aacd97d13 201 Pfam PF01558 Pyruvate ferredoxin/flavodoxin oxidoreductase 11 190 6.2E-47 T 31-10-2018 IPR019752 Pyruvate/ketoisovalerate oxidoreductase, catalytic domain GO:0016903|GO:0055114 AF_2030 7751e60fd708541da8276d7aacd97d13 201 SUPERFAMILY SSF53323 1 193 4.45E-42 T 31-10-2018 IPR002869 Pyruvate-flavodoxin oxidoreductase, central domain GO:0016491|GO:0055114 AF_2073 f73886a58263dff0b7bff57e3812d533 301 Gene3D G3DSA:3.30.70.520 4 296 3.4E-114 T 31-10-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily AF_2073 f73886a58263dff0b7bff57e3812d533 301 Gene3D G3DSA:3.30.70.520 18 165 3.4E-114 T 31-10-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily AF_2073 f73886a58263dff0b7bff57e3812d533 301 SUPERFAMILY SSF55112 150 297 3.66E-52 T 31-10-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily AF_2073 f73886a58263dff0b7bff57e3812d533 301 SUPERFAMILY SSF55112 2 148 6.8E-45 T 31-10-2018 IPR023447 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, ferredoxin-like superfamily AF_2073 f73886a58263dff0b7bff57e3812d533 301 PIRSF PIRSF006414 2 298 7.8E-140 T 31-10-2018 IPR014053 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr GO:0006730|GO:0030270 AF_2073 f73886a58263dff0b7bff57e3812d533 301 Pfam PF02741 FTR, proximal lobe 150 296 9.7E-58 T 31-10-2018 IPR002770 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, C-terminal GO:0006730|GO:0016740 AF_2073 f73886a58263dff0b7bff57e3812d533 301 Pfam PF01913 Formylmethanofuran-tetrahydromethanopterin formyltransferase 2 147 2.2E-47 T 31-10-2018 IPR022667 Formylmethanofuran: tetrahydromethanopterin formyltransferase Ftr, N-terminal GO:0006730|GO:0016740 AF_1225 bac7caa201eeeb7b8e6314615cadc494 212 Gene3D G3DSA:3.40.50.300 28 194 1.1E-6 T 31-10-2018 AF_1225 bac7caa201eeeb7b8e6314615cadc494 212 SUPERFAMILY SSF52540 95 200 7.43E-6 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1535 c78301a8c08099e12d5e1dfa578ded66 94 SUPERFAMILY SSF57662 2 93 1.16E-29 T 31-10-2018 IPR036644 Ferredoxin thioredoxin reductase catalytic beta subunit superfamily GO:0016730|GO:0055114 AF_1535 c78301a8c08099e12d5e1dfa578ded66 94 Pfam PF02943 Ferredoxin thioredoxin reductase catalytic beta chain 1 81 3.7E-21 T 31-10-2018 IPR004209 Ferredoxin thioredoxin reductase catalytic beta subunit GO:0016730|GO:0055114 AF_1535 c78301a8c08099e12d5e1dfa578ded66 94 Gene3D G3DSA:3.90.460.10 1 89 1.9E-17 T 31-10-2018 IPR036644 Ferredoxin thioredoxin reductase catalytic beta subunit superfamily GO:0016730|GO:0055114 AF_0555 1158cf3167afc05a036ca31360d7b18a 127 Gene3D G3DSA:3.40.1260.10 1 127 7.5E-26 T 31-10-2018 IPR027396 DsrEFH-like AF_0555 1158cf3167afc05a036ca31360d7b18a 127 SUPERFAMILY SSF75169 1 122 2.55E-14 T 31-10-2018 IPR027396 DsrEFH-like AF_0555 1158cf3167afc05a036ca31360d7b18a 127 Pfam PF13686 DsrE/DsrF/DrsH-like family 2 49 1.2E-6 T 31-10-2018 IPR032836 DsrE2-like family AF_0555 1158cf3167afc05a036ca31360d7b18a 127 Pfam PF13686 DsrE/DsrF/DrsH-like family 60 124 2.3E-7 T 31-10-2018 IPR032836 DsrE2-like family AF_2217 c2b99d86969474f57b5e2bbaa66854e3 516 Pfam PF01039 Carboxyl transferase domain 27 514 5.3E-206 T 31-10-2018 IPR034733 Acetyl-CoA carboxylase MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722|Reactome: R-HSA-196780 AF_2217 c2b99d86969474f57b5e2bbaa66854e3 516 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 94 108 8.5E-5 T 31-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AF_2217 c2b99d86969474f57b5e2bbaa66854e3 516 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 194 205 8.5E-5 T 31-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AF_2217 c2b99d86969474f57b5e2bbaa66854e3 516 PRINTS PR01070 Acetyl-CoA carboxylase carboxyl transferase beta subunit signature 128 146 8.5E-5 T 31-10-2018 IPR000438 Acetyl-CoA carboxylase carboxyl transferase, beta subunit GO:0003989|GO:0006633|GO:0009317 MetaCyc: PWY-4381|MetaCyc: PWY-5743|MetaCyc: PWY-5744|MetaCyc: PWY-5789|MetaCyc: PWY-6722 AF_2217 c2b99d86969474f57b5e2bbaa66854e3 516 Gene3D G3DSA:3.90.226.10 261 516 2.3E-96 T 31-10-2018 AF_2217 c2b99d86969474f57b5e2bbaa66854e3 516 SUPERFAMILY SSF52096 226 516 2.26E-95 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AF_2217 c2b99d86969474f57b5e2bbaa66854e3 516 TIGRFAM TIGR01117 mmdA: methylmalonyl-CoA decarboxylase alpha subunit 4 516 0.0 T 31-10-2018 IPR005783 Methylmalonyl-CoA decarboxylase, alpha subunit AF_2217 c2b99d86969474f57b5e2bbaa66854e3 516 SUPERFAMILY SSF52096 5 256 8.54E-81 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AF_2217 c2b99d86969474f57b5e2bbaa66854e3 516 Gene3D G3DSA:3.90.226.10 1 258 2.0E-97 T 31-10-2018 AF_2083 36e6245746251463e6c211daa3297df6 83 Pfam PF14947 Winged helix-turn-helix 4 82 2.7E-26 T 31-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain AF_2083 36e6245746251463e6c211daa3297df6 83 Gene3D G3DSA:1.10.10.10 2 83 2.2E-25 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_2083 36e6245746251463e6c211daa3297df6 83 SUPERFAMILY SSF46785 5 81 1.66E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_2070 7b243139c557af394ba45cba4ea75d07 75 Pfam PF01985 CRS1 / YhbY (CRM) domain 7 73 5.1E-10 T 31-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 AF_2070 7b243139c557af394ba45cba4ea75d07 75 Gene3D G3DSA:3.30.110.60 2 75 6.9E-13 T 31-10-2018 IPR035920 YhbY-like superfamily AF_2070 7b243139c557af394ba45cba4ea75d07 75 SUPERFAMILY SSF75471 6 73 3.27E-12 T 31-10-2018 IPR035920 YhbY-like superfamily AF_2070 7b243139c557af394ba45cba4ea75d07 75 ProDom PD010559 RNA-BINDING YHBY UPF0044 PREDICTED RNA RIBOSOMAL CONTAINING KH BINDING DOMAIN 7 75 2.0E-7 T 31-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 AF_2070 7b243139c557af394ba45cba4ea75d07 75 SMART SM01103 1 75 2.6E-14 T 31-10-2018 IPR001890 RNA-binding, CRM domain GO:0003723 AF_2278 f0b3d494f486ac362e8a7b6a631c234d 330 TIGRFAM TIGR04337 AmmeMemoSam_rS: AmmeMemoRadiSam system radical SAM enzyme 10 329 2.0E-69 T 31-10-2018 IPR027596 AmmeMemoRadiSam system radical SAM enzyme AF_2278 f0b3d494f486ac362e8a7b6a631c234d 330 PIRSF PIRSF004869 1 306 2.2E-94 T 31-10-2018 IPR016431 Pyruvate-formate lyase-activating enzyme, predicted AF_2278 f0b3d494f486ac362e8a7b6a631c234d 330 Pfam PF04055 Radical SAM superfamily 77 225 4.5E-19 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_2278 f0b3d494f486ac362e8a7b6a631c234d 330 Gene3D G3DSA:3.20.20.70 74 323 1.4E-23 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_2278 f0b3d494f486ac362e8a7b6a631c234d 330 SUPERFAMILY SSF102114 55 307 7.06E-35 T 31-10-2018 AF_1827 4678be783158cffad8692e71c4e6b748 404 Pfam PF00361 Proton-conducting membrane transporter 91 353 1.0E-20 T 31-10-2018 IPR001750 NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_0021 9d83db63f22e754d5d1841181f78e7f2 323 SUPERFAMILY SSF55874 187 322 2.1E-27 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_0021 9d83db63f22e754d5d1841181f78e7f2 323 Gene3D G3DSA:3.30.450.20 2 123 3.5E-12 T 31-10-2018 AF_0021 9d83db63f22e754d5d1841181f78e7f2 323 SUPERFAMILY SSF55785 5 108 4.01E-12 T 31-10-2018 IPR035965 PAS domain superfamily AF_0021 9d83db63f22e754d5d1841181f78e7f2 323 SMART SM00091 3 66 1.7E-6 T 31-10-2018 IPR000014 PAS domain AF_0021 9d83db63f22e754d5d1841181f78e7f2 323 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 3 116 7.1E-10 T 31-10-2018 IPR000014 PAS domain AF_0021 9d83db63f22e754d5d1841181f78e7f2 323 SMART SM00387 219 323 2.8E-29 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_0021 9d83db63f22e754d5d1841181f78e7f2 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 285 303 2.3E-10 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_0021 9d83db63f22e754d5d1841181f78e7f2 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 255 269 2.3E-10 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_0021 9d83db63f22e754d5d1841181f78e7f2 323 PRINTS PR00344 Bacterial sensor protein C-terminal signature 273 283 2.3E-10 T 31-10-2018 IPR004358 Signal transduction histidine kinase-related protein, C-terminal GO:0016310|GO:0016772 Reactome: R-HSA-70895 AF_0021 9d83db63f22e754d5d1841181f78e7f2 323 Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase 222 322 1.2E-19 T 31-10-2018 IPR003594 Histidine kinase/HSP90-like ATPase AF_0021 9d83db63f22e754d5d1841181f78e7f2 323 Pfam PF13426 PAS domain 13 108 5.8E-8 T 31-10-2018 IPR000014 PAS domain AF_0021 9d83db63f22e754d5d1841181f78e7f2 323 Gene3D G3DSA:3.30.565.10 187 323 1.3E-29 T 31-10-2018 IPR036890 Histidine kinase/HSP90-like ATPase superfamily AF_1084 b6e64ec013f5effd440b1d0e58d23a0b 63 Gene3D G3DSA:4.10.1150.10 1 62 3.1E-18 T 31-10-2018 IPR024069 AF2212-like domain superfamily AF_1084 b6e64ec013f5effd440b1d0e58d23a0b 63 Pfam PF01954 Protein of unknown function DUF104 1 56 6.2E-19 T 31-10-2018 IPR008203 Uncharacterised protein family UPF0165 AF_1084 b6e64ec013f5effd440b1d0e58d23a0b 63 SUPERFAMILY SSF141694 1 56 6.02E-18 T 31-10-2018 AF_1813 a10d2dae6a338a8c923618d53d380ba7 449 Gene3D G3DSA:1.10.8.60 358 447 1.3E-26 T 31-10-2018 AF_1813 a10d2dae6a338a8c923618d53d380ba7 449 Gene3D G3DSA:2.40.50.360 119 246 3.2E-111 T 31-10-2018 AF_1813 a10d2dae6a338a8c923618d53d380ba7 449 SUPERFAMILY SSF52540 37 428 5.32E-38 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1813 a10d2dae6a338a8c923618d53d380ba7 449 SMART SM00382 62 357 1.8E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1813 a10d2dae6a338a8c923618d53d380ba7 449 Pfam PF06068 TIP49 C-terminus 14 406 9.7E-176 T 31-10-2018 IPR010339 TIP49, C-terminal GO:0003678|GO:0005524 Reactome: R-HSA-171319|Reactome: R-HSA-3214847 AF_1813 a10d2dae6a338a8c923618d53d380ba7 449 Gene3D G3DSA:3.40.50.300 17 353 3.2E-111 T 31-10-2018 AF_0360 3534e2c42dc0aba90216b7f0238e69ec 232 Pfam PF07758 Protein of unknown function (DUF1614) 54 226 4.0E-50 T 31-10-2018 IPR011672 Protein of unknown function DUF1614 AF_1723 69e9452ba007cba0497ebaa900554c95 138 Pfam PF13404 AsnC-type helix-turn-helix domain 2 42 6.8E-12 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_1723 69e9452ba007cba0497ebaa900554c95 138 SUPERFAMILY SSF46785 1 60 1.08E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1723 69e9452ba007cba0497ebaa900554c95 138 Gene3D G3DSA:3.30.70.920 64 138 2.0E-15 T 31-10-2018 AF_1723 69e9452ba007cba0497ebaa900554c95 138 SUPERFAMILY SSF54909 65 138 6.61E-13 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel AF_1723 69e9452ba007cba0497ebaa900554c95 138 SMART SM00344 1 106 5.8E-33 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AF_1723 69e9452ba007cba0497ebaa900554c95 138 Pfam PF01037 Lrp/AsnC ligand binding domain 67 134 7.6E-12 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AF_1723 69e9452ba007cba0497ebaa900554c95 138 Gene3D G3DSA:1.10.10.10 1 52 1.1E-14 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1723 69e9452ba007cba0497ebaa900554c95 138 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 28 47 3.8E-7 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_1723 69e9452ba007cba0497ebaa900554c95 138 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 17 28 3.8E-7 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_1723 69e9452ba007cba0497ebaa900554c95 138 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 1 17 3.8E-7 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_1474 40eda2519068c99c0477c11c1914a215 448 ProSitePatterns PS00455 Putative AMP-binding domain signature. 75 86 - T 31-10-2018 IPR020845 AMP-binding, conserved site AF_1284 384f41dc3e3c00fcbfdb87465bc4db3e 134 Gene3D G3DSA:3.40.30.10 25 134 1.3E-40 T 31-10-2018 AF_1284 384f41dc3e3c00fcbfdb87465bc4db3e 134 PRINTS PR00421 Thioredoxin family signature 58 67 1.3E-8 T 31-10-2018 AF_1284 384f41dc3e3c00fcbfdb87465bc4db3e 134 PRINTS PR00421 Thioredoxin family signature 98 109 1.3E-8 T 31-10-2018 AF_1284 384f41dc3e3c00fcbfdb87465bc4db3e 134 PRINTS PR00421 Thioredoxin family signature 50 58 1.3E-8 T 31-10-2018 AF_1284 384f41dc3e3c00fcbfdb87465bc4db3e 134 Pfam PF00085 Thioredoxin 33 132 9.6E-35 T 31-10-2018 IPR013766 Thioredoxin domain GO:0045454 AF_1284 384f41dc3e3c00fcbfdb87465bc4db3e 134 SUPERFAMILY SSF52833 2 134 4.76E-44 T 31-10-2018 IPR036249 Thioredoxin-like superfamily AF_1284 384f41dc3e3c00fcbfdb87465bc4db3e 134 PIRSF PIRSF000077 29 134 3.3E-39 T 31-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AF_1284 384f41dc3e3c00fcbfdb87465bc4db3e 134 TIGRFAM TIGR01068 thioredoxin: thioredoxin 36 133 2.8E-42 T 31-10-2018 IPR005746 Thioredoxin GO:0006662|GO:0015035|GO:0045454 AF_0203 b863671cb841bdadc9f66d8c6e1cc816 149 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 24 58 3.3E-11 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AF_0203 b863671cb841bdadc9f66d8c6e1cc816 149 SUPERFAMILY SSF50249 4 140 2.91E-34 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0203 b863671cb841bdadc9f66d8c6e1cc816 149 Gene3D G3DSA:1.10.12.20 2 64 8.1E-23 T 31-10-2018 AF_0203 b863671cb841bdadc9f66d8c6e1cc816 149 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 61 132 1.1E-15 T 31-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AF_2365 a6e68b3ec32e23618afae2e229b24608 369 SUPERFAMILY SSF101960 47 363 1.44E-79 T 31-10-2018 IPR037284 SUF system FeS cluster assembly, SufBD superfamily AF_2365 a6e68b3ec32e23618afae2e229b24608 369 Pfam PF01458 Uncharacterized protein family (UPF0051) 120 341 7.2E-54 T 31-10-2018 IPR000825 SUF system FeS cluster assembly, SufBD GO:0016226 AF_0755 db647a39c87010657bee62c464e677b5 654 Gene3D G3DSA:1.10.1060.10 247 370 7.0E-14 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_0755 db647a39c87010657bee62c464e677b5 654 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 337 348 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0755 db647a39c87010657bee62c464e677b5 654 Pfam PF02754 Cysteine-rich domain 537 624 2.2E-18 T 31-10-2018 IPR004017 Cysteine-rich domain AF_0755 db647a39c87010657bee62c464e677b5 654 Pfam PF02754 Cysteine-rich domain 418 503 4.7E-16 T 31-10-2018 IPR004017 Cysteine-rich domain AF_0755 db647a39c87010657bee62c464e677b5 654 Pfam PF13183 4Fe-4S dicluster domain 275 350 5.0E-12 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_0755 db647a39c87010657bee62c464e677b5 654 Pfam PF02665 Nitrate reductase gamma subunit 80 245 3.8E-6 T 31-10-2018 IPR023234 NarG-like domain AF_0755 db647a39c87010657bee62c464e677b5 654 SUPERFAMILY SSF103501 15 246 1.96E-35 T 31-10-2018 IPR036197 NarG-like superfamily AF_0755 db647a39c87010657bee62c464e677b5 654 Gene3D G3DSA:1.20.950.20 71 243 1.8E-9 T 31-10-2018 AF_0755 db647a39c87010657bee62c464e677b5 654 SUPERFAMILY SSF46548 265 365 1.34E-19 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_1833 c199d84c2c12bcb6185f9d0bc75f0eaa 379 SUPERFAMILY SSF54862 59 154 4.9E-12 T 31-10-2018 AF_1833 c199d84c2c12bcb6185f9d0bc75f0eaa 379 Gene3D G3DSA:3.30.70.20 51 117 8.5E-12 T 31-10-2018 AF_1833 c199d84c2c12bcb6185f9d0bc75f0eaa 379 Pfam PF13237 4Fe-4S dicluster domain 59 107 7.0E-6 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1833 c199d84c2c12bcb6185f9d0bc75f0eaa 379 Pfam PF04422 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term 124 197 7.2E-14 T 31-10-2018 IPR007516 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, N-terminal AF_1833 c199d84c2c12bcb6185f9d0bc75f0eaa 379 Pfam PF04432 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit C terminus 205 350 7.8E-38 T 31-10-2018 IPR007525 Coenzyme F420 hydrogenase/dehydrogenase beta subunit, C-terminal AF_1833 c199d84c2c12bcb6185f9d0bc75f0eaa 379 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 96 107 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_2271 ce17c446ae188740d14bc97331cfd750 255 SUPERFAMILY SSF46785 9 110 1.46E-18 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_2271 ce17c446ae188740d14bc97331cfd750 255 Gene3D G3DSA:1.10.10.10 1 72 1.7E-12 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_2271 ce17c446ae188740d14bc97331cfd750 255 SMART SM00418 2 86 1.7E-4 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_2271 ce17c446ae188740d14bc97331cfd750 255 PIRSF PIRSF006692 1 255 1.3E-71 T 31-10-2018 IPR016490 Transcriptional regulator, HTH, AF0396-type AF_2271 ce17c446ae188740d14bc97331cfd750 255 Pfam PF08350 Domain of unknown function (DUF1724) 197 250 4.6E-15 T 31-10-2018 IPR013561 Domain of unknown function DUF1724 AF_2271 ce17c446ae188740d14bc97331cfd750 255 SMART SM00419 16 65 6.5E-10 T 31-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AF_2271 ce17c446ae188740d14bc97331cfd750 255 Pfam PF01022 Bacterial regulatory protein, arsR family 12 56 1.3E-14 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_0489 1b2b6df3729fb34438394076ea5ae351 132 Gene3D G3DSA:3.30.70.3250 21 132 3.0E-34 T 31-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 AF_0489 1b2b6df3729fb34438394076ea5ae351 132 PIRSF PIRSF004952 23 132 5.5E-38 T 31-10-2018 IPR016434 Ribonuclease P, protein component 2 GO:0001682|GO:0004526 AF_0489 1b2b6df3729fb34438394076ea5ae351 132 Pfam PF01900 Rpp14/Pop5 family 36 129 5.2E-18 T 31-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 AF_0489 1b2b6df3729fb34438394076ea5ae351 132 SUPERFAMILY SSF160350 24 131 8.11E-30 T 31-10-2018 IPR038085 Rnp2-like domain superfamily Reactome: R-HSA-6784531 AF_0489 1b2b6df3729fb34438394076ea5ae351 132 Hamap MF_00755 Ribonuclease P protein component 2 [rnp2]. 24 132 24.503 T 31-10-2018 IPR002759 Ribonuclease P/MRP protein subunit GO:0004540|GO:0008033 Reactome: R-HSA-6784531 AF_0206 bdf4ef5a99dd582ede94f8476515cf2c 179 SUPERFAMILY SSF110324 3 42 2.09E-10 T 31-10-2018 AF_0206 bdf4ef5a99dd582ede94f8476515cf2c 179 SMART SM00316 56 132 0.0081 T 31-10-2018 IPR022967 RNA-binding domain, S1 AF_0206 bdf4ef5a99dd582ede94f8476515cf2c 179 Pfam PF14382 Exosome complex exonuclease RRP4 N-terminal region 3 39 8.4E-12 T 31-10-2018 IPR025721 Exosome complex component, N-terminal domain Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AF_0206 bdf4ef5a99dd582ede94f8476515cf2c 179 Hamap MF_00975 Exosome complex component Csl4 [csl4]. 3 176 25.253 T 31-10-2018 IPR030850 Exosome complex component Csl4, archaea GO:0000178|GO:0006396 AF_0206 bdf4ef5a99dd582ede94f8476515cf2c 179 Gene3D G3DSA:2.40.50.140 53 138 2.2E-20 T 31-10-2018 AF_0206 bdf4ef5a99dd582ede94f8476515cf2c 179 SUPERFAMILY SSF50249 54 170 1.07E-19 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0206 bdf4ef5a99dd582ede94f8476515cf2c 179 Gene3D G3DSA:2.20.70.10 139 172 2.8E-21 T 31-10-2018 AF_0206 bdf4ef5a99dd582ede94f8476515cf2c 179 Pfam PF10447 Exosome component EXOSC1/CSL4 52 172 1.6E-26 T 31-10-2018 IPR019495 Exosome complex component CSL4, C-terminal GO:0000178|GO:0003723 Reactome: R-HSA-380994|Reactome: R-HSA-429958|Reactome: R-HSA-450385|Reactome: R-HSA-450513|Reactome: R-HSA-450604|Reactome: R-HSA-6791226 AF_0206 bdf4ef5a99dd582ede94f8476515cf2c 179 Gene3D G3DSA:2.40.50.100 1 52 3.4E-25 T 31-10-2018 AF_0255 6736d4198d1c037750ed17a452ee623e 87 Gene3D G3DSA:1.10.10.10 4 86 2.4E-15 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0255 6736d4198d1c037750ed17a452ee623e 87 SUPERFAMILY SSF46785 5 73 1.9E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1315 6a210240efc6470d46317d530e586f3f 331 SUPERFAMILY SSF89796 1 330 7.46E-88 T 31-10-2018 IPR023606 CoA-transferase family III domain superfamily AF_1315 6a210240efc6470d46317d530e586f3f 331 Gene3D G3DSA:3.30.1540.10 209 295 1.8E-85 T 31-10-2018 AF_1315 6a210240efc6470d46317d530e586f3f 331 Gene3D G3DSA:3.40.50.10540 2 301 1.8E-85 T 31-10-2018 IPR023606 CoA-transferase family III domain superfamily AF_1315 6a210240efc6470d46317d530e586f3f 331 Pfam PF02515 CoA-transferase family III 2 330 2.5E-75 T 31-10-2018 IPR003673 CoA-transferase family III GO:0003824 AF_2372 00600e873d3c21962d17ac29d1b30e3c 252 Gene3D G3DSA:3.40.190.80 139 252 1.1E-32 T 31-10-2018 AF_2372 00600e873d3c21962d17ac29d1b30e3c 252 Pfam PF00459 Inositol monophosphatase family 13 250 6.6E-28 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AF_2372 00600e873d3c21962d17ac29d1b30e3c 252 Gene3D G3DSA:3.30.540.10 1 138 1.1E-35 T 31-10-2018 AF_2372 00600e873d3c21962d17ac29d1b30e3c 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 40 60 1.9E-21 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AF_2372 00600e873d3c21962d17ac29d1b30e3c 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 196 220 1.9E-21 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AF_2372 00600e873d3c21962d17ac29d1b30e3c 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 130 153 1.9E-21 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AF_2372 00600e873d3c21962d17ac29d1b30e3c 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 79 95 1.9E-21 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AF_2372 00600e873d3c21962d17ac29d1b30e3c 252 PRINTS PR00377 Inositol monophosphatase superfamily signature 161 182 1.9E-21 T 31-10-2018 IPR000760 Inositol monophosphatase-like GO:0046854 AF_2372 00600e873d3c21962d17ac29d1b30e3c 252 ProSitePatterns PS00630 Inositol monophosphatase family signature 2. 199 213 - T 31-10-2018 IPR020550 Inositol monophosphatase, conserved site GO:0046854 AF_2372 00600e873d3c21962d17ac29d1b30e3c 252 SUPERFAMILY SSF56655 1 251 4.45E-56 T 31-10-2018 AF_1706 8eeb0ede2d75eb3dd3289013ebe56f03 238 PRINTS PR00111 Alpha/beta hydrolase fold signature 110 123 3.8E-12 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_1706 8eeb0ede2d75eb3dd3289013ebe56f03 238 PRINTS PR00111 Alpha/beta hydrolase fold signature 96 109 3.8E-12 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_1706 8eeb0ede2d75eb3dd3289013ebe56f03 238 PRINTS PR00111 Alpha/beta hydrolase fold signature 53 68 3.8E-12 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_1706 8eeb0ede2d75eb3dd3289013ebe56f03 238 PRINTS PR00111 Alpha/beta hydrolase fold signature 208 222 3.8E-12 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_1706 8eeb0ede2d75eb3dd3289013ebe56f03 238 SUPERFAMILY SSF53474 9 234 5.99E-57 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_1706 8eeb0ede2d75eb3dd3289013ebe56f03 238 Gene3D G3DSA:3.40.50.1820 4 238 4.1E-53 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_1706 8eeb0ede2d75eb3dd3289013ebe56f03 238 Pfam PF00561 alpha/beta hydrolase fold 29 136 3.1E-23 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_0405 faaa5d9f79a29ae5cc34485f97eb39a8 83 Gene3D G3DSA:2.20.28.30 1 42 3.0E-5 T 31-10-2018 AF_0364 9bf7f9d4b273c1e4d18a3846b248bb10 621 Pfam PF13654 AAA domain 168 395 2.0E-25 T 31-10-2018 AF_0364 9bf7f9d4b273c1e4d18a3846b248bb10 621 SUPERFAMILY SSF54211 426 599 2.43E-42 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AF_0364 9bf7f9d4b273c1e4d18a3846b248bb10 621 TIGRFAM TIGR00764 lon_rel: putative ATP-dependent protease 11 615 0.0 T 31-10-2018 IPR004663 Lon protease, archaeal GO:0004176|GO:0005524|GO:0030163 AF_0364 9bf7f9d4b273c1e4d18a3846b248bb10 621 Gene3D G3DSA:3.30.230.10 415 621 1.5E-79 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AF_0364 9bf7f9d4b273c1e4d18a3846b248bb10 621 SUPERFAMILY SSF52540 23 399 2.11E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0364 9bf7f9d4b273c1e4d18a3846b248bb10 621 SMART SM00382 46 304 4.4E-9 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0364 9bf7f9d4b273c1e4d18a3846b248bb10 621 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 503 522 1.1E-29 T 31-10-2018 AF_0364 9bf7f9d4b273c1e4d18a3846b248bb10 621 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 54 73 1.1E-29 T 31-10-2018 AF_0364 9bf7f9d4b273c1e4d18a3846b248bb10 621 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 426 442 1.1E-29 T 31-10-2018 AF_0364 9bf7f9d4b273c1e4d18a3846b248bb10 621 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 533 552 1.1E-29 T 31-10-2018 AF_0364 9bf7f9d4b273c1e4d18a3846b248bb10 621 PRINTS PR00830 Endopeptidase La (Lon) serine protease (S16) signature 556 574 1.1E-29 T 31-10-2018 AF_0364 9bf7f9d4b273c1e4d18a3846b248bb10 621 Pfam PF05362 Lon protease (S16) C-terminal proteolytic domain 409 601 9.4E-31 T 31-10-2018 IPR008269 Peptidase S16, Lon proteolytic domain GO:0004176|GO:0004252|GO:0006508 AF_0364 9bf7f9d4b273c1e4d18a3846b248bb10 621 Gene3D G3DSA:3.40.50.300 10 121 9.0E-31 T 31-10-2018 AF_0364 9bf7f9d4b273c1e4d18a3846b248bb10 621 Gene3D G3DSA:3.40.50.300 155 306 7.9E-39 T 31-10-2018 AF_0364 9bf7f9d4b273c1e4d18a3846b248bb10 621 Gene3D G3DSA:1.10.8.60 307 399 1.9E-41 T 31-10-2018 AF_0364 9bf7f9d4b273c1e4d18a3846b248bb10 621 Pfam PF01078 Magnesium chelatase, subunit ChlI 28 80 7.1E-11 T 31-10-2018 IPR000523 Magnesium chelatase ChlI domain AF_1168 465c31a91dd1e6135db626b95128e5ec 209 Hamap MF_00271 V-type ATP synthase subunit D [atpD]. 1 209 25.528 T 31-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AF_1168 465c31a91dd1e6135db626b95128e5ec 209 TIGRFAM TIGR00309 V_ATPase_subD: V-type ATPase, D subunit 1 208 2.4E-94 T 31-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AF_1168 465c31a91dd1e6135db626b95128e5ec 209 Pfam PF01813 ATP synthase subunit D 10 203 9.7E-58 T 31-10-2018 IPR002699 ATPase, V1 complex, subunit D GO:0042626 Reactome: R-HSA-1222556|Reactome: R-HSA-6798695|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AF_1914 d56bd938f9d01ff015e3176ba9c78d94 120 SUPERFAMILY SSF50104 7 107 2.41E-31 T 31-10-2018 IPR008991 Translation protein SH3-like domain superfamily AF_1914 d56bd938f9d01ff015e3176ba9c78d94 120 Pfam PF00467 KOW motif 50 81 4.8E-9 T 31-10-2018 IPR005824 KOW AF_1914 d56bd938f9d01ff015e3176ba9c78d94 120 ProSitePatterns PS01108 Ribosomal protein L24 signature. 51 68 - T 31-10-2018 IPR005825 Ribosomal protein L24/L26, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1914 d56bd938f9d01ff015e3176ba9c78d94 120 TIGRFAM TIGR01080 rplX_A_E: ribosomal protein uL24 6 120 1.4E-56 T 31-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1914 d56bd938f9d01ff015e3176ba9c78d94 120 SMART SM00739 47 74 1.2E-6 T 31-10-2018 IPR005824 KOW AF_1914 d56bd938f9d01ff015e3176ba9c78d94 120 Hamap MF_01326_A 50S ribosomal protein L24 [rplX]. 6 120 30.106 T 31-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1914 d56bd938f9d01ff015e3176ba9c78d94 120 Pfam PF16906 Ribosomal proteins L26 eukaryotic, L24P archaeal 6 120 5.9E-29 T 31-10-2018 IPR005756 Ribosomal protein L26/L24, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1914 d56bd938f9d01ff015e3176ba9c78d94 120 Gene3D G3DSA:2.30.30.30 2 120 7.6E-45 T 31-10-2018 IPR014722 Ribosomal protein L2, domain 2 AF_1775 c4c22164254cf3c04040c61a6cc78757 330 Gene3D G3DSA:3.20.20.140 50 289 9.1E-17 T 31-10-2018 AF_1775 c4c22164254cf3c04040c61a6cc78757 330 Pfam PF01979 Amidohydrolase family 45 270 1.6E-5 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AF_1775 c4c22164254cf3c04040c61a6cc78757 330 SUPERFAMILY SSF51556 48 285 2.69E-25 T 31-10-2018 IPR032466 Metal-dependent hydrolase AF_2405 22233cd69e0bf1e11020b56ec2014c00 92 Pfam PF01893 Uncharacterised protein family UPF0058 7 87 9.0E-27 T 31-10-2018 IPR002753 Uncharacterised protein family UPF0058 AF_2405 22233cd69e0bf1e11020b56ec2014c00 92 Gene3D G3DSA:1.20.1270.110 6 77 9.8E-21 T 31-10-2018 IPR036519 Uncharacterised UPF0058 superfamily AF_2405 22233cd69e0bf1e11020b56ec2014c00 92 SUPERFAMILY SSF140371 6 87 2.09E-25 T 31-10-2018 IPR036519 Uncharacterised UPF0058 superfamily AF_1215 f7489a19e60458ed452ecf6b483ed639 394 SMART SM00864 5 204 1.3E-21 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AF_1215 f7489a19e60458ed452ecf6b483ed639 394 SUPERFAMILY SSF52490 4 200 2.49E-41 T 31-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AF_1215 f7489a19e60458ed452ecf6b483ed639 394 Gene3D G3DSA:3.30.1330.20 233 369 1.9E-41 T 31-10-2018 IPR037103 Tubulin/FtsZ, C-terminal domain superfamily Reactome: R-HSA-380320 AF_1215 f7489a19e60458ed452ecf6b483ed639 394 Pfam PF00091 Tubulin/FtsZ family, GTPase domain 7 175 3.3E-27 T 31-10-2018 IPR003008 Tubulin/FtsZ, GTPase domain GO:0003924 Reactome: R-HSA-380320 AF_1215 f7489a19e60458ed452ecf6b483ed639 394 Hamap MF_01946 Tubulin-like protein CetZ [cetZ]. 4 393 37.265 T 31-10-2018 IPR032907 Tubulin-like protein CetZ GO:0008360 AF_1215 f7489a19e60458ed452ecf6b483ed639 394 ProSitePatterns PS00227 Tubulin subunits alpha, beta, and gamma signature. 111 117 - T 31-10-2018 IPR017975 Tubulin, conserved site GO:0005525|GO:0005874|GO:0007017 Reactome: R-HSA-380320 AF_1215 f7489a19e60458ed452ecf6b483ed639 394 Gene3D G3DSA:3.40.50.1440 4 232 9.7E-79 T 31-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AF_1624 4690587582178ce55ab4b628c9884e1a 86 Gene3D G3DSA:3.10.20.30 1 86 1.1E-27 T 31-10-2018 IPR012675 Beta-grasp domain superfamily AF_1624 4690587582178ce55ab4b628c9884e1a 86 SUPERFAMILY SSF54285 2 86 9.53E-24 T 31-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AF_1624 4690587582178ce55ab4b628c9884e1a 86 TIGRFAM TIGR01687 moaD_arch: MoaD family protein 2 86 1.0E-31 T 31-10-2018 IPR010038 MoaD, archaeal-type AF_1624 4690587582178ce55ab4b628c9884e1a 86 Pfam PF02597 ThiS family 4 86 1.1E-19 T 31-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 AF_1238 5e02a3e25d424e6e1b28182ed2d60cef 769 Pfam PF00037 4Fe-4S binding domain 285 305 1.7E-4 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1238 5e02a3e25d424e6e1b28182ed2d60cef 769 SUPERFAMILY SSF54862 526 624 3.94E-21 T 31-10-2018 AF_1238 5e02a3e25d424e6e1b28182ed2d60cef 769 Gene3D G3DSA:3.50.50.60 418 489 1.2E-9 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1238 5e02a3e25d424e6e1b28182ed2d60cef 769 Pfam PF02662 Methyl-viologen-reducing hydrogenase, delta subunit 647 767 5.7E-49 T 31-10-2018 IPR003813 F420-non-reducing hydrogenase iron-sulfur subunit D GO:0055114 AF_1238 5e02a3e25d424e6e1b28182ed2d60cef 769 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 576 587 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1238 5e02a3e25d424e6e1b28182ed2d60cef 769 Gene3D G3DSA:3.30.70.20 596 637 1.6E-6 T 31-10-2018 AF_1238 5e02a3e25d424e6e1b28182ed2d60cef 769 Gene3D G3DSA:3.30.70.20 551 595 8.5E-7 T 31-10-2018 AF_1238 5e02a3e25d424e6e1b28182ed2d60cef 769 Pfam PF13187 4Fe-4S dicluster domain 575 619 8.9E-8 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1238 5e02a3e25d424e6e1b28182ed2d60cef 769 Gene3D G3DSA:3.40.50.720 137 232 3.4E-13 T 31-10-2018 AF_1238 5e02a3e25d424e6e1b28182ed2d60cef 769 Gene3D G3DSA:3.50.50.60 490 537 1.2E-9 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1238 5e02a3e25d424e6e1b28182ed2d60cef 769 Pfam PF07992 Pyridine nucleotide-disulphide oxidoreductase 142 543 6.7E-20 T 31-10-2018 IPR023753 FAD/NAD(P)-binding domain GO:0016491|GO:0055114 AF_1238 5e02a3e25d424e6e1b28182ed2d60cef 769 Gene3D G3DSA:3.30.70.20 236 338 3.8E-11 T 31-10-2018 AF_1238 5e02a3e25d424e6e1b28182ed2d60cef 769 SUPERFAMILY SSF51905 140 554 1.23E-39 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1238 5e02a3e25d424e6e1b28182ed2d60cef 769 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 604 615 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1185 9fdd7fca1ff68208e000ef3cecffec3d 131 Gene3D G3DSA:3.30.70.20 51 92 4.5E-5 T 31-10-2018 AF_1185 9fdd7fca1ff68208e000ef3cecffec3d 131 SUPERFAMILY SSF54862 64 129 2.36E-23 T 31-10-2018 AF_1185 9fdd7fca1ff68208e000ef3cecffec3d 131 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 82 93 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1185 9fdd7fca1ff68208e000ef3cecffec3d 131 SMART SM00930 2 71 1.7E-7 T 31-10-2018 IPR018449 NIL domain AF_1185 9fdd7fca1ff68208e000ef3cecffec3d 131 Pfam PF09383 NIL domain 8 68 5.4E-9 T 31-10-2018 IPR018449 NIL domain AF_1185 9fdd7fca1ff68208e000ef3cecffec3d 131 SUPERFAMILY SSF55021 6 70 5.38E-9 T 31-10-2018 AF_1185 9fdd7fca1ff68208e000ef3cecffec3d 131 Pfam PF12838 4Fe-4S dicluster domain 81 126 2.9E-12 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1185 9fdd7fca1ff68208e000ef3cecffec3d 131 Gene3D G3DSA:3.30.70.20 93 130 4.3E-13 T 31-10-2018 AF_1185 9fdd7fca1ff68208e000ef3cecffec3d 131 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 112 123 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0055 954ec794601aab2bc1e524be408b0628 132 Pfam PF01989 Protein of unknown function DUF126 24 102 3.0E-32 T 31-10-2018 IPR002840 Aconitase X swivel domain, putative AF_0055 954ec794601aab2bc1e524be408b0628 132 Hamap MF_00078 UPF0107 protein . 2 131 32.206 T 31-10-2018 IPR020794 Aconitase X subunit 2, archaeal, putative AF_0055 954ec794601aab2bc1e524be408b0628 132 Gene3D G3DSA:3.50.30.10 1 132 3.6E-58 T 31-10-2018 AF_0055 954ec794601aab2bc1e524be408b0628 132 PIRSF PIRSF004966 1 132 2.9E-54 T 31-10-2018 IPR012016 Aconitase X subunit 2, putative AF_0055 954ec794601aab2bc1e524be408b0628 132 SUPERFAMILY SSF52016 3 130 3.3E-44 T 31-10-2018 AF_0986 147845b8bd3038e8c6500d165b6f9bd5 238 TIGRFAM TIGR00007 TIGR00007: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase 4 230 5.1E-79 T 31-10-2018 IPR006063 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase HisA GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 AF_0986 147845b8bd3038e8c6500d165b6f9bd5 238 Hamap MF_01014 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [hisA]. 3 233 32.078 T 31-10-2018 IPR023016 Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase GO:0000105|GO:0003949 KEGG: 00340+5.3.1.16 AF_0986 147845b8bd3038e8c6500d165b6f9bd5 238 Pfam PF00977 Histidine biosynthesis protein 3 225 1.3E-65 T 31-10-2018 IPR006062 Histidine biosynthesis GO:0000105 AF_0986 147845b8bd3038e8c6500d165b6f9bd5 238 SUPERFAMILY SSF51366 2 232 2.42E-62 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AF_0986 147845b8bd3038e8c6500d165b6f9bd5 238 Gene3D G3DSA:3.20.20.70 1 236 6.2E-68 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0856 17fa814c001b65ff2a6a39255299dd7f 291 Gene3D G3DSA:3.90.226.10 70 262 3.4E-22 T 31-10-2018 AF_0856 17fa814c001b65ff2a6a39255299dd7f 291 SUPERFAMILY SSF52096 66 248 6.63E-28 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AF_0856 17fa814c001b65ff2a6a39255299dd7f 291 Pfam PF01972 Serine dehydrogenase proteinase 8 286 1.2E-164 T 31-10-2018 IPR002825 Peptidase S49, serine-peptidase prokaryotes GO:0016021 AF_1733 10209f8e3c248bab26113284485431b1 45 Pfam PF10133 Predicted RNA-binding protein 1 43 5.4E-14 T 31-10-2018 IPR019300 RNA-binding protein, predicted AF_1753 35ac8dcad50ee8128c1d23319a00f062 266 Pfam PF12146 Serine aminopeptidase, S33 20 250 3.7E-75 T 31-10-2018 IPR022742 Serine aminopeptidase, S33 AF_1753 35ac8dcad50ee8128c1d23319a00f062 266 Gene3D G3DSA:3.40.50.1820 1 265 5.1E-71 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_1753 35ac8dcad50ee8128c1d23319a00f062 266 SUPERFAMILY SSF53474 4 263 3.46E-49 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_1753 35ac8dcad50ee8128c1d23319a00f062 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 206 220 1.3E-5 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_1753 35ac8dcad50ee8128c1d23319a00f062 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 94 107 1.3E-5 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_1753 35ac8dcad50ee8128c1d23319a00f062 266 PRINTS PR00111 Alpha/beta hydrolase fold signature 49 64 1.3E-5 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_0135 cbcd7f7a7e98fbaf9d85d2224e2e6ed9 148 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 33 59 1.6E-5 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AF_0135 cbcd7f7a7e98fbaf9d85d2224e2e6ed9 148 Gene3D G3DSA:1.10.12.20 3 68 6.5E-18 T 31-10-2018 AF_0135 cbcd7f7a7e98fbaf9d85d2224e2e6ed9 148 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 67 130 1.1E-7 T 31-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AF_0135 cbcd7f7a7e98fbaf9d85d2224e2e6ed9 148 SUPERFAMILY SSF50249 10 137 4.63E-25 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0339 d542a66d0c857d0d202c94d750d69216 395 Gene3D G3DSA:3.40.50.1970 12 194 8.4E-44 T 31-10-2018 AF_0339 d542a66d0c857d0d202c94d750d69216 395 Gene3D G3DSA:1.20.1090.10 195 393 6.8E-54 T 31-10-2018 AF_0339 d542a66d0c857d0d202c94d750d69216 395 SUPERFAMILY SSF56796 15 391 5.23E-100 T 31-10-2018 AF_0339 d542a66d0c857d0d202c94d750d69216 395 ProSitePatterns PS00913 Iron-containing alcohol dehydrogenases signature 1. 183 211 - T 31-10-2018 IPR018211 Alcohol dehydrogenase, iron-type, conserved site GO:0016491|GO:0046872|GO:0055114 AF_0339 d542a66d0c857d0d202c94d750d69216 395 Pfam PF00465 Iron-containing alcohol dehydrogenase 23 378 9.6E-97 T 31-10-2018 IPR001670 Alcohol dehydrogenase, iron-type/glycerol dehydrogenase GldA GO:0016491|GO:0046872|GO:0055114 Reactome: R-HSA-880009 AF_2017 ecd012ee58695565cef0442719f3a823 281 PIRSF PIRSF000105 1 281 3.1E-87 T 31-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 AF_2017 ecd012ee58695565cef0442719f3a823 281 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 2 159 2.7E-43 T 31-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_2017 ecd012ee58695565cef0442719f3a823 281 Gene3D G3DSA:3.40.50.720 1 162 3.4E-65 T 31-10-2018 AF_2017 ecd012ee58695565cef0442719f3a823 281 SUPERFAMILY SSF51735 2 160 7.37E-44 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_2017 ecd012ee58695565cef0442719f3a823 281 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 164 259 4.9E-21 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_2017 ecd012ee58695565cef0442719f3a823 281 Gene3D G3DSA:1.10.1040.10 163 279 2.8E-27 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AF_2017 ecd012ee58695565cef0442719f3a823 281 SUPERFAMILY SSF48179 163 263 6.55E-22 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_0797 f9a2509e551ea0ccc71a73c6397569d0 324 Pfam PF04055 Radical SAM superfamily 12 177 5.2E-13 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_0797 f9a2509e551ea0ccc71a73c6397569d0 324 Hamap MF_01611 FO synthase subunit 1 [cofG]. 4 314 52.615 T 31-10-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77 AF_0797 f9a2509e551ea0ccc71a73c6397569d0 324 SMART SM00729 8 223 4.6E-15 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AF_0797 f9a2509e551ea0ccc71a73c6397569d0 324 Gene3D G3DSA:3.20.20.70 2 265 1.9E-43 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0797 f9a2509e551ea0ccc71a73c6397569d0 324 SUPERFAMILY SSF102114 9 281 1.02E-41 T 31-10-2018 AF_0797 f9a2509e551ea0ccc71a73c6397569d0 324 TIGRFAM TIGR03550 F420_cofG: 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase, CofG subunit 5 312 6.0E-135 T 31-10-2018 IPR019939 CofG family GO:0009108|GO:0016765|GO:0051539 KEGG: 00680+2.5.1.77 AF_1797 3be09e9dec7d5b679969740b6bfcc59b 321 SMART SM00966 9 54 1.2E-7 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AF_1797 3be09e9dec7d5b679969740b6bfcc59b 321 Gene3D G3DSA:1.20.58.220 122 233 8.2E-19 T 31-10-2018 IPR038078 PhoU-like domain superfamily AF_1797 3be09e9dec7d5b679969740b6bfcc59b 321 SUPERFAMILY SSF109755 133 319 4.92E-33 T 31-10-2018 AF_1797 3be09e9dec7d5b679969740b6bfcc59b 321 Gene3D G3DSA:1.20.58.220 234 321 2.2E-7 T 31-10-2018 IPR038078 PhoU-like domain superfamily AF_1797 3be09e9dec7d5b679969740b6bfcc59b 321 Pfam PF01895 PhoU domain 241 314 3.2E-6 T 31-10-2018 IPR026022 PhoU domain AF_1797 3be09e9dec7d5b679969740b6bfcc59b 321 Pfam PF01895 PhoU domain 135 225 9.3E-18 T 31-10-2018 IPR026022 PhoU domain AF_1797 3be09e9dec7d5b679969740b6bfcc59b 321 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 10 51 4.4E-9 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AF_0847 f432b8f8ebc6b31fd1aa4af58de6b5ee 189 SUPERFAMILY SSF54631 4 126 3.79E-36 T 31-10-2018 AF_0847 f432b8f8ebc6b31fd1aa4af58de6b5ee 189 Pfam PF00571 CBS domain 7 61 1.0E-11 T 31-10-2018 IPR000644 CBS domain AF_0847 f432b8f8ebc6b31fd1aa4af58de6b5ee 189 Pfam PF00571 CBS domain 72 126 2.2E-17 T 31-10-2018 IPR000644 CBS domain AF_0847 f432b8f8ebc6b31fd1aa4af58de6b5ee 189 Gene3D G3DSA:3.10.580.10 2 156 1.2E-42 T 31-10-2018 AF_0847 f432b8f8ebc6b31fd1aa4af58de6b5ee 189 SMART SM00116 79 127 3.0E-16 T 31-10-2018 IPR000644 CBS domain AF_0847 f432b8f8ebc6b31fd1aa4af58de6b5ee 189 SMART SM00116 14 61 5.1E-7 T 31-10-2018 IPR000644 CBS domain AF_1810 98cebd5b3b9d47bb3f720c6bc9de3aba 259 SUPERFAMILY SSF102114 8 177 8.89E-26 T 31-10-2018 AF_1810 98cebd5b3b9d47bb3f720c6bc9de3aba 259 Gene3D G3DSA:3.20.20.70 2 237 6.3E-27 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1810 98cebd5b3b9d47bb3f720c6bc9de3aba 259 Pfam PF04055 Radical SAM superfamily 8 131 3.0E-15 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_1318 3f35d35e5e78719e03d02c455aaa139c 427 Gene3D G3DSA:3.30.420.10 173 427 6.8E-69 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AF_1318 3f35d35e5e78719e03d02c455aaa139c 427 SUPERFAMILY SSF53098 2 427 5.31E-64 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily AF_1318 3f35d35e5e78719e03d02c455aaa139c 427 Pfam PF02171 Piwi domain 111 405 1.0E-70 T 31-10-2018 IPR003165 Piwi domain GO:0003676 AF_1318 3f35d35e5e78719e03d02c455aaa139c 427 SMART SM00950 110 406 1.7E-40 T 31-10-2018 IPR003165 Piwi domain GO:0003676 AF_1318 3f35d35e5e78719e03d02c455aaa139c 427 Gene3D G3DSA:3.40.50.2300 1 172 2.7E-119 T 31-10-2018 AF_0979 8654ac9f4793074455ee6b2619001162 204 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 28 194 6.3E-20 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AF_0979 8654ac9f4793074455ee6b2619001162 204 SUPERFAMILY SSF161098 8 188 2.09E-34 T 31-10-2018 IPR035906 MetI-like superfamily AF_0979 8654ac9f4793074455ee6b2619001162 204 Gene3D G3DSA:1.10.3720.10 4 196 2.1E-28 T 31-10-2018 IPR035906 MetI-like superfamily AF_0982 e085c5eecc1beeda85236abc910258a8 292 Gene3D G3DSA:3.40.190.10 26 290 3.5E-102 T 31-10-2018 AF_0982 e085c5eecc1beeda85236abc910258a8 292 SUPERFAMILY SSF53850 24 291 1.23E-71 T 31-10-2018 AF_0982 e085c5eecc1beeda85236abc910258a8 292 Pfam PF04069 Substrate binding domain of ABC-type glycine betaine transport system 24 287 7.4E-64 T 31-10-2018 IPR007210 ABC-type glycine betaine transport system, substrate-binding domain GO:0022857|GO:0043190|GO:0055085 AF_0982 e085c5eecc1beeda85236abc910258a8 292 Gene3D G3DSA:3.40.190.120 127 230 3.5E-102 T 31-10-2018 AF_1702 045e9a66c29a066f7997e2062cea9755 294 SUPERFAMILY SSF52518 2 287 7.23E-76 T 31-10-2018 IPR029061 Thiamin diphosphate-binding fold AF_1702 045e9a66c29a066f7997e2062cea9755 294 Pfam PF02775 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain 37 200 1.4E-27 T 31-10-2018 IPR011766 Thiamine pyrophosphate enzyme, C-terminal TPP-binding GO:0003824|GO:0030976 AF_1702 045e9a66c29a066f7997e2062cea9755 294 Gene3D G3DSA:3.40.50.970 4 81 2.7E-13 T 31-10-2018 AF_1702 045e9a66c29a066f7997e2062cea9755 294 Gene3D G3DSA:3.40.50.970 82 290 2.7E-62 T 31-10-2018 AF_0262 9e3979a722f453b8a95c45e725525c7f 551 Gene3D G3DSA:3.40.50.12780 3 444 1.5E-112 T 31-10-2018 AF_0262 9e3979a722f453b8a95c45e725525c7f 551 Pfam PF13193 AMP-binding enzyme C-terminal domain 459 535 1.0E-20 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AF_0262 9e3979a722f453b8a95c45e725525c7f 551 Pfam PF00501 AMP-binding enzyme 24 449 1.7E-89 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_0262 9e3979a722f453b8a95c45e725525c7f 551 SUPERFAMILY SSF56801 7 548 9.81E-134 T 31-10-2018 AF_0262 9e3979a722f453b8a95c45e725525c7f 551 Gene3D G3DSA:3.30.300.310 445 551 1.3E-36 T 31-10-2018 AF_0090 93394ad74cc7660811e7853290ed4dfe 293 Gene3D G3DSA:3.60.15.10 2 229 1.8E-41 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_0090 93394ad74cc7660811e7853290ed4dfe 293 Pfam PF00753 Metallo-beta-lactamase superfamily 23 203 4.6E-22 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_0090 93394ad74cc7660811e7853290ed4dfe 293 SMART SM00849 24 203 2.7E-24 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_0090 93394ad74cc7660811e7853290ed4dfe 293 SUPERFAMILY SSF56281 2 261 6.3E-49 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_1634 e3364add886076c926279a284cc99e28 172 SUPERFAMILY SSF102114 1 100 3.92E-9 T 31-10-2018 AF_1717 21fd153d362a60857e85fddc23a03665 140 Pfam PF07849 Protein of unknown function (DUF1641) 106 138 2.9E-14 T 31-10-2018 IPR012440 Protein of unknown function DUF1641 AF_1403 8aa6f4c253ff6fd220ea4cafda4c1746 219 Gene3D G3DSA:3.30.70.260 1 78 1.0E-35 T 31-10-2018 AF_1403 8aa6f4c253ff6fd220ea4cafda4c1746 219 SUPERFAMILY SSF52172 80 217 2.19E-60 T 31-10-2018 IPR011006 CheY-like superfamily AF_1403 8aa6f4c253ff6fd220ea4cafda4c1746 219 Gene3D G3DSA:3.40.50.10550 79 219 7.2E-72 T 31-10-2018 AF_1403 8aa6f4c253ff6fd220ea4cafda4c1746 219 SUPERFAMILY SSF55021 5 75 1.68E-14 T 31-10-2018 AF_1403 8aa6f4c253ff6fd220ea4cafda4c1746 219 Pfam PF01842 ACT domain 5 66 9.4E-7 T 31-10-2018 IPR002912 ACT domain AF_1403 8aa6f4c253ff6fd220ea4cafda4c1746 219 PIRSF PIRSF006363 1 219 1.0E-116 T 31-10-2018 IPR015832 Uncharacterised conserved protein UCP006363, ACT-type AF_0807 82dd036bc0ac019efee8ff027674cd64 366 PIRSF PIRSF000138 33 219 1.1E-33 T 31-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 AF_0807 82dd036bc0ac019efee8ff027674cd64 366 PIRSF PIRSF000138 211 366 5.7E-56 T 31-10-2018 IPR012133 Alpha-hydroxy acid dehydrogenase, FMN-dependent GO:0010181|GO:0016491|GO:0055114 Reactome: R-HSA-9033241 AF_0807 82dd036bc0ac019efee8ff027674cd64 366 Pfam PF01070 FMN-dependent dehydrogenase 75 212 2.4E-16 T 31-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 AF_0807 82dd036bc0ac019efee8ff027674cd64 366 Pfam PF01070 FMN-dependent dehydrogenase 229 364 2.6E-44 T 31-10-2018 IPR000262 FMN-dependent dehydrogenase GO:0016491 Reactome: R-HSA-9033241 AF_0807 82dd036bc0ac019efee8ff027674cd64 366 Gene3D G3DSA:3.20.20.70 217 366 3.0E-40 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0807 82dd036bc0ac019efee8ff027674cd64 366 Gene3D G3DSA:3.20.20.70 54 216 3.6E-15 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0807 82dd036bc0ac019efee8ff027674cd64 366 SUPERFAMILY SSF51395 59 365 1.28E-40 T 31-10-2018 AF_1637 7cb65c2cf0d6257346bc57b97efd2179 394 Gene3D G3DSA:3.50.50.60 17 346 5.1E-54 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1637 7cb65c2cf0d6257346bc57b97efd2179 394 Gene3D G3DSA:3.30.9.10 90 361 5.1E-54 T 31-10-2018 AF_1637 7cb65c2cf0d6257346bc57b97efd2179 394 TIGRFAM TIGR02032 GG-red-SF: geranylgeranyl reductase family 16 311 1.1E-74 T 31-10-2018 IPR011777 Geranylgeranyl reductase family GO:0016628|GO:0055114 AF_1637 7cb65c2cf0d6257346bc57b97efd2179 394 SUPERFAMILY SSF51905 11 353 9.48E-23 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1884 0bd0f8cdb73bfe128150398a8637ee5b 398 TIGRFAM TIGR01188 drrA: daunorubicin resistance ABC transporter, ATP-binding protein 87 377 2.1E-126 T 31-10-2018 IPR005894 Daunorubicin resistance ABC transporter ATP-binding subunit DrrA GO:0005524|GO:0043215|GO:1900753 AF_1884 0bd0f8cdb73bfe128150398a8637ee5b 398 Pfam PF00005 ABC transporter 96 238 3.4E-33 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_1884 0bd0f8cdb73bfe128150398a8637ee5b 398 Gene3D G3DSA:3.40.50.300 70 310 1.2E-72 T 31-10-2018 AF_1884 0bd0f8cdb73bfe128150398a8637ee5b 398 ProSitePatterns PS00211 ABC transporters family signature. 211 225 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_1884 0bd0f8cdb73bfe128150398a8637ee5b 398 SUPERFAMILY SSF52540 79 300 1.33E-67 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1884 0bd0f8cdb73bfe128150398a8637ee5b 398 Pfam PF13732 Domain of unknown function (DUF4162) 293 375 1.9E-8 T 31-10-2018 IPR025302 Domain of unknown function DUF4162 AF_1884 0bd0f8cdb73bfe128150398a8637ee5b 398 SMART SM00382 104 288 1.1E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1374 b988cd953a9c0b707e13ed09ce4de5e6 134 Pfam PF02662 Methyl-viologen-reducing hydrogenase, delta subunit 3 125 9.9E-49 T 31-10-2018 IPR003813 F420-non-reducing hydrogenase iron-sulfur subunit D GO:0055114 AF_0003 976dbd75957cf713a8359861c550e90f 164 Gene3D G3DSA:3.40.33.10 22 159 9.0E-19 T 31-10-2018 IPR035940 CAP superfamily AF_0003 976dbd75957cf713a8359861c550e90f 164 Pfam PF00188 Cysteine-rich secretory protein family 41 155 1.1E-10 T 31-10-2018 IPR014044 CAP domain AF_0003 976dbd75957cf713a8359861c550e90f 164 SUPERFAMILY SSF55797 33 152 7.59E-11 T 31-10-2018 IPR035940 CAP superfamily AF_1148 31945c8f4250cae28d3e2b7da6a1b34c 149 SMART SM00344 4 110 6.7E-49 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AF_1148 31945c8f4250cae28d3e2b7da6a1b34c 149 SUPERFAMILY SSF54909 64 148 1.79E-18 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel AF_1148 31945c8f4250cae28d3e2b7da6a1b34c 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 20 31 9.1E-15 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_1148 31945c8f4250cae28d3e2b7da6a1b34c 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 31 50 9.1E-15 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_1148 31945c8f4250cae28d3e2b7da6a1b34c 149 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 4 20 9.1E-15 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_1148 31945c8f4250cae28d3e2b7da6a1b34c 149 Gene3D G3DSA:3.30.70.920 56 149 2.9E-21 T 31-10-2018 AF_1148 31945c8f4250cae28d3e2b7da6a1b34c 149 Pfam PF01037 Lrp/AsnC ligand binding domain 70 139 4.9E-16 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AF_1148 31945c8f4250cae28d3e2b7da6a1b34c 149 Gene3D G3DSA:1.10.10.10 1 55 3.0E-18 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1148 31945c8f4250cae28d3e2b7da6a1b34c 149 Pfam PF13404 AsnC-type helix-turn-helix domain 4 45 1.1E-15 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_1148 31945c8f4250cae28d3e2b7da6a1b34c 149 SUPERFAMILY SSF46785 3 64 7.53E-16 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0039 adacfd6030ecb1d3d2a1d0aca577e554 369 Gene3D G3DSA:3.90.550.10 1 218 7.3E-45 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0039 adacfd6030ecb1d3d2a1d0aca577e554 369 SUPERFAMILY SSF53448 1 239 1.01E-39 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0039 adacfd6030ecb1d3d2a1d0aca577e554 369 Pfam PF00535 Glycosyl transferase family 2 4 160 1.3E-28 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AF_1867 1fdac06b3af863fde69f31c90c0a896d 1004 Gene3D G3DSA:3.30.70.2220 218 431 2.9E-51 T 31-10-2018 IPR038242 Cmr2, N-terminal domain superfamily AF_1867 1fdac06b3af863fde69f31c90c0a896d 1004 Pfam PF12469 CRISPR-associated protein 249 364 1.3E-30 T 31-10-2018 IPR024615 CRISPR-associated protein Cmr2, N-terminal AF_1867 1fdac06b3af863fde69f31c90c0a896d 1004 TIGRFAM TIGR02577 cas_TM1794_Cmr2: CRISPR-associated protein Cas10/Cmr2, subtype III-B 248 852 4.5E-192 T 31-10-2018 IPR013407 CRISPR-associated protein Cmr2 AF_0134 1b2139982eb99e5749b55806c94298e8 398 PIRSF PIRSF000429 18 383 3.0E-24 T 31-10-2018 IPR002155 Thiolase GO:0016747 AF_0134 1b2139982eb99e5749b55806c94298e8 398 Gene3D G3DSA:3.40.47.10 19 396 5.3E-84 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0134 1b2139982eb99e5749b55806c94298e8 398 SUPERFAMILY SSF53901 42 241 7.88E-22 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_0134 1b2139982eb99e5749b55806c94298e8 398 SUPERFAMILY SSF53901 244 387 9.22E-19 T 31-10-2018 IPR016039 Thiolase-like GO:0003824 AF_1675 469863bf1b6d63f8b08a704dc48d1061 127 Gene3D G3DSA:3.40.30.10 21 117 6.7E-14 T 31-10-2018 AF_1675 469863bf1b6d63f8b08a704dc48d1061 127 SUPERFAMILY SSF52833 6 101 7.08E-17 T 31-10-2018 IPR036249 Thioredoxin-like superfamily AF_1675 469863bf1b6d63f8b08a704dc48d1061 127 Pfam PF13899 Thioredoxin-like 30 91 3.4E-10 T 31-10-2018 AF_1779 a9cb20c821af871055462b2083621d22 323 Pfam PF02826 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain 112 290 5.5E-62 T 31-10-2018 IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain GO:0051287|GO:0055114 AF_1779 a9cb20c821af871055462b2083621d22 323 SUPERFAMILY SSF52283 23 137 8.69E-28 T 31-10-2018 AF_1779 a9cb20c821af871055462b2083621d22 323 Gene3D G3DSA:3.40.50.720 101 291 8.6E-101 T 31-10-2018 AF_1779 a9cb20c821af871055462b2083621d22 323 SUPERFAMILY SSF51735 103 291 9.72E-59 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1779 a9cb20c821af871055462b2083621d22 323 Pfam PF00389 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain 25 321 1.9E-30 T 31-10-2018 IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain GO:0016616|GO:0051287|GO:0055114 AF_1779 a9cb20c821af871055462b2083621d22 323 ProSitePatterns PS00671 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. 228 244 - T 31-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AF_1779 a9cb20c821af871055462b2083621d22 323 ProSitePatterns PS00670 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. 199 221 - T 31-10-2018 IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site AF_1779 a9cb20c821af871055462b2083621d22 323 Gene3D G3DSA:3.40.50.720 25 316 8.6E-101 T 31-10-2018 AF_0348 c11b3b54e368975be7fb0196e942ed69 126 SUPERFAMILY SSF69118 17 122 2.09E-20 T 31-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AF_0348 c11b3b54e368975be7fb0196e942ed69 126 Pfam PF02627 Carboxymuconolactone decarboxylase family 37 109 2.0E-11 T 31-10-2018 IPR003779 Carboxymuconolactone decarboxylase-like GO:0051920|GO:0055114 KEGG: 00480+1.11.1.15 AF_0348 c11b3b54e368975be7fb0196e942ed69 126 Gene3D G3DSA:1.20.1290.10 2 122 2.7E-20 T 31-10-2018 IPR029032 AhpD-like Reactome: R-HSA-5628897 AF_0309 70f113957213edb3c66a7aae903b93b2 299 SUPERFAMILY SSF46689 4 109 8.96E-15 T 31-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AF_0309 70f113957213edb3c66a7aae903b93b2 299 Gene3D G3DSA:3.30.420.10 125 291 3.2E-23 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AF_0309 70f113957213edb3c66a7aae903b93b2 299 SUPERFAMILY SSF53098 125 270 7.08E-28 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily AF_0309 70f113957213edb3c66a7aae903b93b2 299 Pfam PF13518 Helix-turn-helix domain 12 58 2.7E-9 T 31-10-2018 AF_0309 70f113957213edb3c66a7aae903b93b2 299 Pfam PF00665 Integrase core domain 129 245 1.8E-23 T 31-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AF_1977 70fe33cc7205b332aff0d770e996e671 159 SMART SM00530 77 132 5.3E-13 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AF_1977 70fe33cc7205b332aff0d770e996e671 159 Gene3D G3DSA:1.10.260.40 65 159 1.8E-18 T 31-10-2018 AF_1977 70fe33cc7205b332aff0d770e996e671 159 TIGRFAM TIGR00270 TIGR00270: TIGR00270 family protein 4 156 6.3E-69 T 31-10-2018 IPR004451 Conserved hypothetical protein CHP00270 AF_1977 70fe33cc7205b332aff0d770e996e671 159 SUPERFAMILY SSF47413 72 133 1.01E-12 T 31-10-2018 IPR010982 Lambda repressor-like, DNA-binding domain superfamily GO:0003677 AF_1977 70fe33cc7205b332aff0d770e996e671 159 Pfam PF01381 Helix-turn-helix 78 131 7.9E-14 T 31-10-2018 IPR001387 Cro/C1-type helix-turn-helix domain GO:0043565 AF_0810 56008ccb0df9b6296944bd97d87df2c7 123 Pfam PF02589 LUD domain 85 120 4.6E-5 T 31-10-2018 IPR003741 LUD domain AF_0810 56008ccb0df9b6296944bd97d87df2c7 123 Gene3D G3DSA:3.40.50.10420 3 120 1.1E-12 T 31-10-2018 IPR024185 5-formyltetrahydrofolate cyclo-ligase-like domain superfamily AF_0810 56008ccb0df9b6296944bd97d87df2c7 123 SUPERFAMILY SSF100950 35 120 6.7E-11 T 31-10-2018 IPR037171 NagB/RpiA transferase-like AF_1172 9ad62ba986c65f6e3fdab1af82985ce5 236 Pfam PF06745 KaiC 9 229 1.2E-6 T 31-10-2018 IPR014774 KaiC-like domain AF_1172 9ad62ba986c65f6e3fdab1af82985ce5 236 SUPERFAMILY SSF52540 9 229 1.02E-11 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1172 9ad62ba986c65f6e3fdab1af82985ce5 236 Gene3D G3DSA:3.40.50.300 4 235 2.8E-22 T 31-10-2018 AF_2249 8f1822ae70b694565033d6d901309774 121 SUPERFAMILY SSF52172 4 116 1.85E-32 T 31-10-2018 IPR011006 CheY-like superfamily AF_2249 8f1822ae70b694565033d6d901309774 121 Pfam PF00072 Response regulator receiver domain 7 112 1.4E-25 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_2249 8f1822ae70b694565033d6d901309774 121 Gene3D G3DSA:3.40.50.2300 2 120 1.8E-34 T 31-10-2018 AF_2249 8f1822ae70b694565033d6d901309774 121 SMART SM00448 4 112 8.3E-29 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_0087 48bc3920d703bfe71f7d7b9ab06b43ec 243 SUPERFAMILY SSF52540 1 212 2.07E-69 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0087 48bc3920d703bfe71f7d7b9ab06b43ec 243 Gene3D G3DSA:3.40.50.300 1 241 7.0E-65 T 31-10-2018 AF_0087 48bc3920d703bfe71f7d7b9ab06b43ec 243 ProSitePatterns PS00211 ABC transporters family signature. 129 143 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_0087 48bc3920d703bfe71f7d7b9ab06b43ec 243 Pfam PF00005 ABC transporter 17 156 1.7E-34 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0087 48bc3920d703bfe71f7d7b9ab06b43ec 243 SMART SM00382 26 205 1.8E-17 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0820 348d23a4b7eff3a778a27a465d8c1c72 94 Gene3D G3DSA:1.10.287.1080 1 77 4.1E-23 T 31-10-2018 AF_0820 348d23a4b7eff3a778a27a465d8c1c72 94 SUPERFAMILY SSF101386 2 84 2.94E-19 T 31-10-2018 AF_0820 348d23a4b7eff3a778a27a465d8c1c72 94 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 23 75 7.2E-10 T 31-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core AF_0691 e4eaed1295d2f282ebf666a625bf0686 585 SUPERFAMILY SSF54292 2 95 1.05E-21 T 31-10-2018 IPR036010 2Fe-2S ferredoxin-like superfamily GO:0009055|GO:0051536 AF_0691 e4eaed1295d2f282ebf666a625bf0686 585 Gene3D G3DSA:3.10.20.30 3 93 2.4E-24 T 31-10-2018 IPR012675 Beta-grasp domain superfamily AF_0691 e4eaed1295d2f282ebf666a625bf0686 585 Pfam PF14574 Domain of unknown function (DUF4445) 164 568 2.3E-136 T 31-10-2018 IPR027980 Protein of unknown function DUF4445 AF_0691 e4eaed1295d2f282ebf666a625bf0686 585 Gene3D G3DSA:3.30.420.480 162 337 9.9E-52 T 31-10-2018 AF_0691 e4eaed1295d2f282ebf666a625bf0686 585 SUPERFAMILY SSF53067 166 504 6.31E-6 T 31-10-2018 AF_0691 e4eaed1295d2f282ebf666a625bf0686 585 Pfam PF00111 2Fe-2S iron-sulfur cluster binding domain 9 80 1.0E-13 T 31-10-2018 IPR001041 2Fe-2S ferredoxin-type iron-sulfur binding domain GO:0009055|GO:0051536 AF_0357 40aa5a30450060ac1219d3c66bf40692 468 Pfam PF05626 Protein of unknown function (DUF790) 1 376 1.2E-124 T 31-10-2018 IPR008508 Protein of unknown function DUF790, endonuclease-like AF_0357 40aa5a30450060ac1219d3c66bf40692 468 Gene3D G3DSA:3.40.91.30 267 343 1.7E-5 T 31-10-2018 IPR011578 T7 endonuclease I-like GO:0003677|GO:0004536 AF_0357 40aa5a30450060ac1219d3c66bf40692 468 PIRSF PIRSF019435 1 466 5.5E-173 T 31-10-2018 IPR008508 Protein of unknown function DUF790, endonuclease-like AF_1065 aea8d2801aa62f4ac534283fc10d9f0f 108 Gene3D G3DSA:2.30.130.30 1 95 5.9E-27 T 31-10-2018 AF_1065 aea8d2801aa62f4ac534283fc10d9f0f 108 SMART SM01022 1 93 6.0E-4 T 31-10-2018 IPR007374 ASCH domain AF_1065 aea8d2801aa62f4ac534283fc10d9f0f 108 Pfam PF04266 ASCH domain 2 91 1.5E-10 T 31-10-2018 IPR007374 ASCH domain AF_1065 aea8d2801aa62f4ac534283fc10d9f0f 108 SUPERFAMILY SSF88697 1 104 4.97E-26 T 31-10-2018 IPR015947 PUA-like superfamily AF_0984 cf81e4fbf54f8749280fb9e578670358 217 SUPERFAMILY SSF52540 1 204 1.31E-53 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0984 cf81e4fbf54f8749280fb9e578670358 217 Gene3D G3DSA:3.40.50.300 1 216 2.0E-59 T 31-10-2018 AF_0984 cf81e4fbf54f8749280fb9e578670358 217 Pfam PF00005 ABC transporter 17 154 9.0E-30 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0984 cf81e4fbf54f8749280fb9e578670358 217 SMART SM00382 25 206 2.0E-11 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1217 37bbaa769723047edd94e1eb9300d357 341 Pfam PF04055 Radical SAM superfamily 40 134 1.3E-12 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_1217 37bbaa769723047edd94e1eb9300d357 341 SUPERFAMILY SSF102114 31 264 7.32E-22 T 31-10-2018 AF_1217 37bbaa769723047edd94e1eb9300d357 341 Gene3D G3DSA:3.20.20.70 28 317 3.0E-13 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1217 37bbaa769723047edd94e1eb9300d357 341 Pfam PF13353 4Fe-4S single cluster domain 32 114 3.3E-6 T 31-10-2018 AF_1404 d640e3af006dd85407dc4b3e4fab9650 77 SUPERFAMILY SSF54909 4 72 1.18E-18 T 31-10-2018 IPR011008 Dimeric alpha-beta barrel AF_1404 d640e3af006dd85407dc4b3e4fab9650 77 Pfam PF01037 Lrp/AsnC ligand binding domain 6 72 2.6E-19 T 31-10-2018 IPR019887 Transcription regulator AsnC/Lrp, ligand binding domain AF_1404 d640e3af006dd85407dc4b3e4fab9650 77 Gene3D G3DSA:3.30.70.920 3 73 1.1E-24 T 31-10-2018 AF_2090-C 002f0133e404122e3051df38c76d6098 569 SMART SM00710 302 324 150.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_2090-C 002f0133e404122e3051df38c76d6098 569 SMART SM00710 169 191 1500.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_2090-C 002f0133e404122e3051df38c76d6098 569 SMART SM00710 273 295 350.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_2090-C 002f0133e404122e3051df38c76d6098 569 SMART SM00710 246 272 83.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_2090-C 002f0133e404122e3051df38c76d6098 569 SMART SM00710 112 133 3000.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_2090-C 002f0133e404122e3051df38c76d6098 569 SMART SM00710 223 245 100.0 T 31-10-2018 IPR006626 Parallel beta-helix repeat AF_2090-C 002f0133e404122e3051df38c76d6098 569 Gene3D G3DSA:2.160.20.10 94 346 2.7E-17 T 31-10-2018 IPR012334 Pectin lyase fold AF_2090-C 002f0133e404122e3051df38c76d6098 569 SUPERFAMILY SSF51126 98 341 3.32E-13 T 31-10-2018 IPR011050 Pectin lyase fold/virulence factor AF_2090-C 002f0133e404122e3051df38c76d6098 569 Pfam PF13229 Right handed beta helix region 164 334 3.2E-10 T 31-10-2018 IPR039448 Right handed beta helix domain AF_0237 fb984c7e9596153547972423b6499f39 461 Gene3D G3DSA:1.20.1730.10 21 461 4.8E-55 T 31-10-2018 IPR038377 Sodium/glucose symporter superfamily AF_0237 fb984c7e9596153547972423b6499f39 461 Pfam PF00474 Sodium:solute symporter family 35 350 1.8E-34 T 31-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AF_0129 e446005c235b357d2b99c7f329fa284c 221 Pfam PF04493 Endonuclease V 15 205 8.7E-58 T 31-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 AF_0129 e446005c235b357d2b99c7f329fa284c 221 Gene3D G3DSA:3.30.2170.10 1 219 7.1E-65 T 31-10-2018 AF_0129 e446005c235b357d2b99c7f329fa284c 221 Hamap MF_00801 Endonuclease V [nfi]. 5 214 33.093 T 31-10-2018 IPR007581 Endonuclease V GO:0004519|GO:0006281 AF_0715 8aa79f5038f45a96423c5e97cf2bcad3 141 Gene3D G3DSA:1.10.287.70 1 98 4.7E-29 T 31-10-2018 AF_0715 8aa79f5038f45a96423c5e97cf2bcad3 141 SUPERFAMILY SSF81324 4 129 8.9E-23 T 31-10-2018 AF_0715 8aa79f5038f45a96423c5e97cf2bcad3 141 Pfam PF07885 Ion channel 11 87 1.1E-15 T 31-10-2018 IPR013099 Potassium channel domain AF_2115 83f8d3b3866ac9e04bcbabffea6f314a 320 Pfam PF13641 Glycosyltransferase like family 2 3 224 3.2E-17 T 31-10-2018 AF_2115 83f8d3b3866ac9e04bcbabffea6f314a 320 SUPERFAMILY SSF53448 4 275 3.28E-34 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_2115 83f8d3b3866ac9e04bcbabffea6f314a 320 Gene3D G3DSA:3.90.550.10 2 205 2.3E-27 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_2018 fcd994aab3d351428e290bb7ff4e1bdc 244 Pfam PF01925 Sulfite exporter TauE/SafE 10 232 1.1E-16 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AF_1383 499319a926855f5b05d0fd23e8036eac 299 Pfam PF13518 Helix-turn-helix domain 12 58 2.2E-8 T 31-10-2018 AF_1383 499319a926855f5b05d0fd23e8036eac 299 SUPERFAMILY SSF46689 4 109 3.63E-14 T 31-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AF_1383 499319a926855f5b05d0fd23e8036eac 299 Pfam PF00665 Integrase core domain 129 245 1.5E-25 T 31-10-2018 IPR001584 Integrase, catalytic core GO:0015074 AF_1383 499319a926855f5b05d0fd23e8036eac 299 SUPERFAMILY SSF53098 125 270 1.01E-28 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily AF_1383 499319a926855f5b05d0fd23e8036eac 299 Gene3D G3DSA:3.30.420.10 124 290 8.5E-23 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AF_1788 e26c4452222527d399fce03d3ad8da9e 243 Gene3D G3DSA:3.40.50.1580 1 243 1.7E-65 T 31-10-2018 AF_1788 e26c4452222527d399fce03d3ad8da9e 243 TIGRFAM TIGR01694 MTAP: methylthioadenosine phosphorylase 1 234 2.8E-88 T 31-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 AF_1788 e26c4452222527d399fce03d3ad8da9e 243 Pfam PF01048 Phosphorylase superfamily 2 232 4.0E-32 T 31-10-2018 IPR000845 Nucleoside phosphorylase domain GO:0003824|GO:0009116 AF_1788 e26c4452222527d399fce03d3ad8da9e 243 Hamap MF_01963 S-methyl-5'-thioadenosine phosphorylase [mtnP]. 1 243 28.22 T 31-10-2018 IPR010044 Methylthioadenosine phosphorylase (MTAP) GO:0017061 Reactome: R-HSA-1237112|Reactome: R-HSA-8950505 AF_1788 e26c4452222527d399fce03d3ad8da9e 243 SUPERFAMILY SSF53167 1 238 4.32E-60 T 31-10-2018 IPR035994 Nucleoside phosphorylase superfamily GO:0003824|GO:0009116 AF_0597 eb3e627acd04056578770b629ff05e81 87 Pfam PF03683 Uncharacterised protein family (UPF0175) 12 81 3.4E-23 T 31-10-2018 IPR005368 Uncharacterised protein family UPF0175 AF_0312 92c3ba834a379ae88c0f2a6faa85cd75 280 SUPERFAMILY SSF53335 11 180 8.55E-31 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_0312 92c3ba834a379ae88c0f2a6faa85cd75 280 Gene3D G3DSA:3.40.50.150 3 227 1.1E-67 T 31-10-2018 AF_0312 92c3ba834a379ae88c0f2a6faa85cd75 280 Pfam PF13578 Methyltransferase domain 42 142 1.7E-7 T 31-10-2018 AF_2369 600095db8935884c88a20b2842cbe893 329 SUPERFAMILY SSF48452 129 323 1.36E-21 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AF_2369 600095db8935884c88a20b2842cbe893 329 SUPERFAMILY SSF103473 2 133 5.62E-5 T 31-10-2018 IPR036259 MFS transporter superfamily AF_2369 600095db8935884c88a20b2842cbe893 329 Gene3D G3DSA:1.25.40.10 91 327 2.4E-15 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AF_1049 c0fb45374a48322a447ac4740102ba1b 628 Gene3D G3DSA:3.40.50.300 339 626 1.4E-92 T 31-10-2018 AF_1049 c0fb45374a48322a447ac4740102ba1b 628 SUPERFAMILY SSF52540 221 611 2.07E-61 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1049 c0fb45374a48322a447ac4740102ba1b 628 Pfam PF00437 Type II/IV secretion system protein 241 511 8.8E-44 T 31-10-2018 IPR001482 Type II/IV secretion system protein AF_0964 3b305bd323e5068bee53fdfc5b5df915 394 Pfam PF00441 Acyl-CoA dehydrogenase, C-terminal domain 235 386 3.2E-33 T 31-10-2018 IPR009075 Acyl-CoA dehydrogenase/oxidase C-terminal GO:0016627|GO:0055114 AF_0964 3b305bd323e5068bee53fdfc5b5df915 394 Gene3D G3DSA:1.10.540.10 1 121 1.2E-33 T 31-10-2018 IPR037069 Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily GO:0016627|GO:0050660|GO:0055114 AF_0964 3b305bd323e5068bee53fdfc5b5df915 394 PIRSF PIRSF016578 3 103 1.1E-6 T 31-10-2018 AF_0964 3b305bd323e5068bee53fdfc5b5df915 394 PIRSF PIRSF016578 235 394 1.7E-13 T 31-10-2018 AF_0964 3b305bd323e5068bee53fdfc5b5df915 394 PIRSF PIRSF016578 128 202 0.056 T 31-10-2018 AF_0964 3b305bd323e5068bee53fdfc5b5df915 394 Pfam PF02771 Acyl-CoA dehydrogenase, N-terminal domain 6 120 9.8E-29 T 31-10-2018 IPR013786 Acyl-CoA dehydrogenase/oxidase, N-terminal GO:0016627|GO:0050660|GO:0055114 AF_0964 3b305bd323e5068bee53fdfc5b5df915 394 Gene3D G3DSA:1.20.140.10 240 392 1.9E-37 T 31-10-2018 AF_0964 3b305bd323e5068bee53fdfc5b5df915 394 Gene3D G3DSA:2.40.110.10 123 239 6.0E-33 T 31-10-2018 AF_0964 3b305bd323e5068bee53fdfc5b5df915 394 SUPERFAMILY SSF56645 1 247 2.88E-71 T 31-10-2018 IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily GO:0016627|GO:0055114 AF_0964 3b305bd323e5068bee53fdfc5b5df915 394 ProSitePatterns PS00073 Acyl-CoA dehydrogenases signature 2. 344 363 - T 31-10-2018 IPR006089 Acyl-CoA dehydrogenase, conserved site GO:0003995|GO:0055114 AF_0964 3b305bd323e5068bee53fdfc5b5df915 394 Pfam PF02770 Acyl-CoA dehydrogenase, middle domain 124 221 5.2E-23 T 31-10-2018 IPR006091 Acyl-CoA oxidase/dehydrogenase, central domain GO:0016627|GO:0055114 AF_0964 3b305bd323e5068bee53fdfc5b5df915 394 SUPERFAMILY SSF47203 234 390 1.01E-42 T 31-10-2018 IPR036250 Acyl-CoA dehydrogenase-like, C-terminal GO:0016627|GO:0055114 AF_0606 c289fb56480c73db62a1b06aba84c168 363 Gene3D G3DSA:3.40.50.2000 169 337 6.4E-33 T 31-10-2018 AF_0606 c289fb56480c73db62a1b06aba84c168 363 SUPERFAMILY SSF53756 3 347 3.72E-47 T 31-10-2018 AF_0606 c289fb56480c73db62a1b06aba84c168 363 Pfam PF00534 Glycosyl transferases group 1 181 337 3.4E-28 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 AF_0688 7fe2940f6b3b2db30ffe7bfeb8e59f3d 368 Pfam PF14697 4Fe-4S dicluster domain 282 336 9.4E-10 T 31-10-2018 AF_0688 7fe2940f6b3b2db30ffe7bfeb8e59f3d 368 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 320 331 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0688 7fe2940f6b3b2db30ffe7bfeb8e59f3d 368 SUPERFAMILY SSF54862 282 342 1.04E-18 T 31-10-2018 AF_0688 7fe2940f6b3b2db30ffe7bfeb8e59f3d 368 Gene3D G3DSA:3.30.70.20 309 343 4.7E-7 T 31-10-2018 AF_0688 7fe2940f6b3b2db30ffe7bfeb8e59f3d 368 Gene3D G3DSA:3.30.70.20 254 308 4.2E-5 T 31-10-2018 AF_0660 a0aeb7e4c4f6db21c5dcd3c6680514f8 91 SUPERFAMILY SSF101386 1 77 1.31E-19 T 31-10-2018 AF_0660 a0aeb7e4c4f6db21c5dcd3c6680514f8 91 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 24 81 1.3E-12 T 31-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core AF_0660 a0aeb7e4c4f6db21c5dcd3c6680514f8 91 Gene3D G3DSA:1.10.287.1080 1 78 1.6E-21 T 31-10-2018 AF_2112 e14e209d0e6fa98f4b4e76490321c7a6 311 Gene3D G3DSA:3.20.20.210 1 310 3.7E-31 T 31-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AF_2112 e14e209d0e6fa98f4b4e76490321c7a6 311 SUPERFAMILY SSF51726 4 308 1.44E-21 T 31-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AF_2261 677f03da4f70ddb54acc4e5feee6beb3 298 Pfam PF08608 Wyosine base formation 236 296 2.0E-21 T 31-10-2018 IPR013917 tRNA wybutosine-synthesis MetaCyc: PWY-7285|MetaCyc: PWY-7286 AF_2261 677f03da4f70ddb54acc4e5feee6beb3 298 Pfam PF04055 Radical SAM superfamily 56 227 1.5E-24 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_2261 677f03da4f70ddb54acc4e5feee6beb3 298 TIGRFAM TIGR03972 rSAM_TYW1: wyosine biosynthesis protein TYW1 10 295 1.9E-125 T 31-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 AF_2261 677f03da4f70ddb54acc4e5feee6beb3 298 Hamap MF_01921 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase [taw1]. 4 296 47.743 T 31-10-2018 IPR023993 S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, archaea GO:0008033|GO:0016829|GO:0051539 MetaCyc: PWY-7285|MetaCyc: PWY-7286 AF_2261 677f03da4f70ddb54acc4e5feee6beb3 298 SUPERFAMILY SSF102114 55 250 5.62E-20 T 31-10-2018 AF_2261 677f03da4f70ddb54acc4e5feee6beb3 298 Gene3D G3DSA:3.20.20.70 1 298 1.7E-112 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0990 f23e07a6face791053bfe4db951d0742 323 SUPERFAMILY SSF89796 2 322 5.23E-106 T 31-10-2018 IPR023606 CoA-transferase family III domain superfamily AF_0990 f23e07a6face791053bfe4db951d0742 323 Pfam PF02515 CoA-transferase family III 1 304 7.5E-99 T 31-10-2018 IPR003673 CoA-transferase family III GO:0003824 AF_0990 f23e07a6face791053bfe4db951d0742 323 Gene3D G3DSA:3.40.50.10540 1 321 3.7E-112 T 31-10-2018 IPR023606 CoA-transferase family III domain superfamily AF_0990 f23e07a6face791053bfe4db951d0742 323 Gene3D G3DSA:3.30.1540.10 164 256 3.7E-112 T 31-10-2018 AF_2190 d78257fa6c866c8847482a51aacd3c74 136 Gene3D G3DSA:3.40.50.1010 2 136 4.0E-21 T 31-10-2018 AF_2190 d78257fa6c866c8847482a51aacd3c74 136 SUPERFAMILY SSF88723 1 133 1.04E-22 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_2190 d78257fa6c866c8847482a51aacd3c74 136 Pfam PF01850 PIN domain 3 132 3.1E-29 T 31-10-2018 IPR002716 PIN domain AF_1446 f5bcf5bca9ac863904df3ad584101557 327 Gene3D G3DSA:3.40.1350.10 204 299 1.1E-8 T 31-10-2018 IPR011856 tRNA endonuclease-like domain superfamily GO:0003676|GO:0004518 AF_0678 cdd9f9091309578700e4e8116d033741 160 Pfam PF13565 Homeodomain-like domain 62 132 1.1E-15 T 31-10-2018 AF_0678 cdd9f9091309578700e4e8116d033741 160 SUPERFAMILY SSF46689 34 136 3.4E-19 T 31-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AF_0298 69f268c643406f8824c2daa82fcb4fce 125 Pfam PF05168 HEPN domain 5 119 6.6E-26 T 31-10-2018 IPR007842 HEPN domain AF_0298 69f268c643406f8824c2daa82fcb4fce 125 Gene3D G3DSA:1.20.120.330 1 125 9.3E-34 T 31-10-2018 AF_1616 e11dcd4d375365830b3156944140f6d6 80 Pfam PF17373 Family of unknown function (DUF5395) 3 79 3.5E-32 T 31-10-2018 IPR035157 Protein of unknown function DUF5395 AF_1616 e11dcd4d375365830b3156944140f6d6 80 ProDom PD750419 PRECURSOR SIGNAL AF1616 11 79 9.0E-27 T 31-10-2018 IPR035157 Protein of unknown function DUF5395 AF_0210 994fbe71fefe9b805f7bb3c7b64cb785 498 Pfam PF09843 Predicted membrane protein (DUF2070) 5 490 2.3E-73 T 31-10-2018 IPR019204 Domain of unknown function DUF2070, membrane AF_1096 747b51c51f9cdef3bcde67beb6d9c4de 141 Pfam PF07790 Archaeal Type IV pilin, N-terminal 9 85 8.0E-27 T 31-10-2018 IPR012859 Archaeal Type IV pilin, N-terminal AF_1096 747b51c51f9cdef3bcde67beb6d9c4de 141 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 9 31 1.3E-7 T 31-10-2018 IPR013373 Flagellin/pilin, N-terminal AF_0341 d47ffbbb693ab4619863a0f5df28ec85 48 Gene3D G3DSA:2.20.28.10 2 36 4.7E-15 T 31-10-2018 AF_0341 d47ffbbb693ab4619863a0f5df28ec85 48 SUPERFAMILY SSF57802 2 35 3.37E-10 T 31-10-2018 AF_0434 d617b858e8b0b579ace2d866a7dae9d8 304 SUPERFAMILY SSF48179 185 291 2.98E-23 T 31-10-2018 IPR008927 6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily GO:0055114 AF_0434 d617b858e8b0b579ace2d866a7dae9d8 304 SUPERFAMILY SSF51735 2 185 9.11E-50 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0434 d617b858e8b0b579ace2d866a7dae9d8 304 PIRSF PIRSF000105 1 300 3.3E-72 T 31-10-2018 IPR022694 3-hydroxyacyl-CoA dehydrogenase GO:0003857|GO:0006631|GO:0055114|GO:0070403 AF_0434 d617b858e8b0b579ace2d866a7dae9d8 304 Gene3D G3DSA:1.10.1040.10 194 277 3.8E-25 T 31-10-2018 IPR013328 6-phosphogluconate dehydrogenase, domain 2 GO:0016491|GO:0055114 AF_0434 d617b858e8b0b579ace2d866a7dae9d8 304 Pfam PF02737 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain 4 183 4.7E-60 T 31-10-2018 IPR006176 3-hydroxyacyl-CoA dehydrogenase, NAD binding GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_0434 d617b858e8b0b579ace2d866a7dae9d8 304 Gene3D G3DSA:3.40.50.720 1 188 1.2E-60 T 31-10-2018 AF_0434 d617b858e8b0b579ace2d866a7dae9d8 304 Pfam PF00725 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain 186 277 1.4E-24 T 31-10-2018 IPR006108 3-hydroxyacyl-CoA dehydrogenase, C-terminal GO:0003857|GO:0006631|GO:0016491|GO:0055114 KEGG: 00062+4.2.1.17+1.1.1.35|KEGG: 00071+4.2.1.17+1.1.1.35|KEGG: 00120+1.1.1.35|KEGG: 00280+4.2.1.17+1.1.1.35|KEGG: 00281+4.2.1.17+1.1.1.35|KEGG: 00310+4.2.1.17+1.1.1.35|KEGG: 00360+4.2.1.17|KEGG: 00362+4.2.1.17+1.1.1.35|KEGG: 00380+4.2.1.17+1.1.1.35|KEGG: 00410+4.2.1.17|KEGG: 00592+4.2.1.17|KEGG: 00623+1.1.1.35|KEGG: 00627+4.2.1.17|KEGG: 00640+4.2.1.17|KEGG: 00650+4.2.1.17+1.1.1.35|KEGG: 00720+4.2.1.17+1.1.1.35|KEGG: 00903+4.2.1.17|KEGG: 00930+4.2.1.17+1.1.1.35|MetaCyc: PWY-1361|MetaCyc: PWY-5109|MetaCyc: PWY-5136|MetaCyc: PWY-5138|MetaCyc: PWY-5177|MetaCyc: PWY-5789|MetaCyc: PWY-6435|MetaCyc: PWY-6583|MetaCyc: PWY-6863|MetaCyc: PWY-6883|MetaCyc: PWY-6944|MetaCyc: PWY-6945|MetaCyc: PWY-6946|MetaCyc: PWY-7007|MetaCyc: PWY-7046|MetaCyc: PWY-7094|MetaCyc: PWY-7216|MetaCyc: PWY-735|MetaCyc: PWY-7401|MetaCyc: PWY-7606|MetaCyc: PWY-7654|MetaCyc: PWY-7656|MetaCyc: PWY-7726|MetaCyc: PWY-7778|MetaCyc: PWY-7779 AF_0166 00501183e82d85d248c2898214d9be1f 60 Gene3D G3DSA:3.30.70.20 1 60 3.8E-21 T 31-10-2018 AF_0166 00501183e82d85d248c2898214d9be1f 60 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 10 21 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_0166 00501183e82d85d248c2898214d9be1f 60 Pfam PF13370 4Fe-4S single cluster domain of Ferredoxin I 5 57 1.2E-14 T 31-10-2018 AF_0166 00501183e82d85d248c2898214d9be1f 60 SUPERFAMILY SSF54862 1 59 6.02E-14 T 31-10-2018 AF_0166 00501183e82d85d248c2898214d9be1f 60 PRINTS PR00352 3Fe-4S ferredoxin signature 44 56 5.6E-10 T 31-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AF_0166 00501183e82d85d248c2898214d9be1f 60 PRINTS PR00352 3Fe-4S ferredoxin signature 16 26 5.6E-10 T 31-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AF_0166 00501183e82d85d248c2898214d9be1f 60 PRINTS PR00352 3Fe-4S ferredoxin signature 5 16 5.6E-10 T 31-10-2018 IPR001080 3Fe-4S ferredoxin GO:0005506|GO:0009055 AF_1679 f79d324f073b8ff54356d393e2220f7e 391 Pfam PF03283 Pectinacetylesterase 83 245 5.9E-12 T 31-10-2018 IPR004963 Pectinacetylesterase/NOTUM GO:0016787 Reactome: R-HSA-381426|Reactome: R-HSA-5362798|Reactome: R-HSA-8957275 AF_1679 f79d324f073b8ff54356d393e2220f7e 391 SUPERFAMILY SSF53474 132 297 1.46E-10 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_1679 f79d324f073b8ff54356d393e2220f7e 391 Gene3D G3DSA:3.40.50.1820 74 284 7.8E-8 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_1943 161afaec9e5ef16be7e9a8d0437c7b2d 548 Gene3D G3DSA:2.60.40.10 49 151 2.3E-19 T 31-10-2018 IPR013783 Immunoglobulin-like fold AF_1943 161afaec9e5ef16be7e9a8d0437c7b2d 548 Gene3D G3DSA:2.60.40.10 294 391 1.4E-18 T 31-10-2018 IPR013783 Immunoglobulin-like fold AF_1943 161afaec9e5ef16be7e9a8d0437c7b2d 548 Pfam PF07705 CARDB 277 386 2.8E-22 T 31-10-2018 IPR011635 CARDB domain AF_1943 161afaec9e5ef16be7e9a8d0437c7b2d 548 Pfam PF07705 CARDB 398 497 1.8E-20 T 31-10-2018 IPR011635 CARDB domain AF_1943 161afaec9e5ef16be7e9a8d0437c7b2d 548 Pfam PF07705 CARDB 49 147 2.1E-21 T 31-10-2018 IPR011635 CARDB domain AF_1943 161afaec9e5ef16be7e9a8d0437c7b2d 548 Pfam PF07705 CARDB 162 264 1.9E-23 T 31-10-2018 IPR011635 CARDB domain AF_1943 161afaec9e5ef16be7e9a8d0437c7b2d 548 Gene3D G3DSA:2.60.40.10 392 505 9.0E-15 T 31-10-2018 IPR013783 Immunoglobulin-like fold AF_1943 161afaec9e5ef16be7e9a8d0437c7b2d 548 Gene3D G3DSA:2.60.40.10 157 270 5.7E-14 T 31-10-2018 IPR013783 Immunoglobulin-like fold AF_0946 0d0265d12da90af1249e7c2c0b6c1ea9 1036 TIGRFAM TIGR04126 PGF_CTERM: PGF-CTERM archaeal protein-sorting signal 1011 1036 1.4E-8 T 31-10-2018 IPR026371 PGF-CTERM archaeal protein-sorting signal AF_1326 ce5c224f67f91d0b96b2989a5858e0ac 197 Gene3D G3DSA:3.40.50.300 4 186 1.4E-33 T 31-10-2018 AF_1326 ce5c224f67f91d0b96b2989a5858e0ac 197 SUPERFAMILY SSF52540 6 172 1.41E-25 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1326 ce5c224f67f91d0b96b2989a5858e0ac 197 Hamap MF_00321 Probable GTP-binding protein EngB [engB]. 1 184 22.977 T 31-10-2018 IPR019987 GTP-binding protein, ribosome biogenesis, YsxC GO:0005525 AF_1326 ce5c224f67f91d0b96b2989a5858e0ac 197 Pfam PF01926 50S ribosome-binding GTPase 5 133 6.7E-16 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 AF_2288 1d961531529d8327386acdb1de9715ef 240 Pfam PF00696 Amino acid kinase family 8 218 3.2E-35 T 31-10-2018 IPR001048 Aspartate/glutamate/uridylate kinase Reactome: R-HSA-70614 AF_2288 1d961531529d8327386acdb1de9715ef 240 Gene3D G3DSA:3.40.1160.10 2 239 8.5E-52 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AF_2288 1d961531529d8327386acdb1de9715ef 240 PIRSF PIRSF016496 4 240 1.5E-69 T 31-10-2018 IPR024192 Fosfomycin resistance kinase, FomA-type GO:0016301 KEGG: 00900+2.7.4.26|MetaCyc: PWY-6174|MetaCyc: PWY-7524 AF_2288 1d961531529d8327386acdb1de9715ef 240 SUPERFAMILY SSF53633 9 238 2.88E-30 T 31-10-2018 IPR036393 Acetylglutamate kinase-like superfamily AF_1640 a51873463b3a3d140d4da9decf7a7eff 164 Gene3D G3DSA:1.20.1260.10 1 126 9.3E-45 T 31-10-2018 IPR012347 Ferritin-like AF_1640 a51873463b3a3d140d4da9decf7a7eff 164 Pfam PF02915 Rubrerythrin 4 118 2.4E-28 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 AF_1640 a51873463b3a3d140d4da9decf7a7eff 164 SUPERFAMILY SSF57802 131 163 1.47E-9 T 31-10-2018 AF_1640 a51873463b3a3d140d4da9decf7a7eff 164 Gene3D G3DSA:2.20.28.10 127 164 8.8E-16 T 31-10-2018 AF_1640 a51873463b3a3d140d4da9decf7a7eff 164 SUPERFAMILY SSF47240 2 124 3.08E-37 T 31-10-2018 IPR009078 Ferritin-like superfamily AF_2099 b9c6a1b65225b395d36d693d595add7a 375 SUPERFAMILY SSF51604 110 374 1.05E-65 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AF_2099 b9c6a1b65225b395d36d693d595add7a 375 Gene3D G3DSA:3.20.20.120 120 375 1.6E-71 T 31-10-2018 IPR036849 Enolase-like, C-terminal domain superfamily AF_2099 b9c6a1b65225b395d36d693d595add7a 375 Gene3D G3DSA:3.30.390.10 7 119 9.0E-14 T 31-10-2018 IPR029017 Enolase-like, N-terminal AF_2099 b9c6a1b65225b395d36d693d595add7a 375 SUPERFAMILY SSF54826 7 126 1.63E-16 T 31-10-2018 AF_2099 b9c6a1b65225b395d36d693d595add7a 375 SMART SM00922 140 243 2.1E-18 T 31-10-2018 IPR013342 Mandelate racemase/muconate lactonizing enzyme, C-terminal AF_2099 b9c6a1b65225b395d36d693d595add7a 375 Pfam PF02746 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain 18 122 2.6E-5 T 31-10-2018 IPR013341 Mandelate racemase/muconate lactonizing enzyme, N-terminal domain AF_2099 b9c6a1b65225b395d36d693d595add7a 375 Pfam PF13378 Enolase C-terminal domain-like 147 367 7.3E-58 T 31-10-2018 IPR029065 Enolase C-terminal domain-like AF_1908 42166973215d072e8a500d77904ff246 129 SMART SM01393 17 126 1.7E-55 T 31-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1908 42166973215d072e8a500d77904ff246 129 ProSitePatterns PS00580 Ribosomal protein L32e signature. 20 41 - T 31-10-2018 IPR018263 Ribosomal protein L32e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1908 42166973215d072e8a500d77904ff246 129 ProDom PD003823 RIBOSOMAL L32 RIBONUCLEOPROTEIN 60S L32E 50S L32 STRAIN CHROMOSOME DIRECT 2 127 3.0E-67 T 31-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1908 42166973215d072e8a500d77904ff246 129 SUPERFAMILY SSF52042 1 128 2.09E-41 T 31-10-2018 IPR036351 Ribosomal protein L32e superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1908 42166973215d072e8a500d77904ff246 129 Hamap MF_00810 50S ribosomal protein L32e [rpl32e]. 1 127 30.398 T 31-10-2018 IPR023654 Ribosomal protein L32e, archaeal GO:0003735|GO:0005840|GO:0006412 AF_1908 42166973215d072e8a500d77904ff246 129 Pfam PF01655 Ribosomal protein L32 17 126 2.2E-35 T 31-10-2018 IPR001515 Ribosomal protein L32e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1471 ee781ba521b3bfe98a29ad751ca8bf7d 447 Pfam PF01554 MatE 239 404 1.3E-33 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AF_1471 ee781ba521b3bfe98a29ad751ca8bf7d 447 Pfam PF01554 MatE 21 180 1.9E-37 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AF_1471 ee781ba521b3bfe98a29ad751ca8bf7d 447 TIGRFAM TIGR00797 matE: MATE efflux family protein 21 413 5.6E-73 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AF_1471 ee781ba521b3bfe98a29ad751ca8bf7d 447 PIRSF PIRSF006603 1 444 3.9E-83 T 31-10-2018 IPR002528 Multi antimicrobial extrusion protein GO:0006855|GO:0015238|GO:0015297|GO:0016020|GO:0055085 Reactome: R-HSA-425366 AF_0973 f6d8c5f81c3b10ad7c3351adec986a87 436 Gene3D G3DSA:3.40.50.10540 19 405 2.2E-102 T 31-10-2018 IPR023606 CoA-transferase family III domain superfamily AF_0973 f6d8c5f81c3b10ad7c3351adec986a87 436 Pfam PF02515 CoA-transferase family III 20 387 2.3E-113 T 31-10-2018 IPR003673 CoA-transferase family III GO:0003824 AF_0973 f6d8c5f81c3b10ad7c3351adec986a87 436 Gene3D G3DSA:3.30.1540.10 243 340 2.2E-102 T 31-10-2018 AF_0973 f6d8c5f81c3b10ad7c3351adec986a87 436 SUPERFAMILY SSF89796 18 411 1.29E-109 T 31-10-2018 IPR023606 CoA-transferase family III domain superfamily AF_0941 006fc6da07e18f5c2736e28b0ccb5be7 114 Pfam PF14591 AF0941-like 1 113 1.4E-37 T 31-10-2018 IPR013502 Uncharacterised domain AF0941 AF_0941 006fc6da07e18f5c2736e28b0ccb5be7 114 SUPERFAMILY SSF140726 1 114 2.09E-71 T 31-10-2018 IPR036564 AF0941-like superfamily AF_0941 006fc6da07e18f5c2736e28b0ccb5be7 114 Gene3D G3DSA:1.10.3200.10 1 114 1.9E-59 T 31-10-2018 IPR036564 AF0941-like superfamily AF_1401 e52864901a84bb4f98a232f07a645229 405 SMART SM00382 27 211 4.9E-16 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1401 e52864901a84bb4f98a232f07a645229 405 ProSitePatterns PS00211 ABC transporters family signature. 136 150 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_1401 e52864901a84bb4f98a232f07a645229 405 SUPERFAMILY SSF52540 3 226 2.42E-59 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1401 e52864901a84bb4f98a232f07a645229 405 ProDom PD064925 ATP-BINDING ABC NUCLEOTIDE-BINDING MEMBRANE TRANSPORTER IRON TRANSPORTER COMPOUND ATPASE III 292 359 9.0E-25 T 31-10-2018 IPR020322 Uncharacterised domain MJ0874 AF_1401 e52864901a84bb4f98a232f07a645229 405 Gene3D G3DSA:3.40.50.300 3 244 6.3E-65 T 31-10-2018 AF_1401 e52864901a84bb4f98a232f07a645229 405 Pfam PF00005 ABC transporter 18 164 1.8E-31 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0539 3096630b700f34f570d71840754f1750 231 Gene3D G3DSA:3.40.50.300 1 229 4.7E-48 T 31-10-2018 AF_0539 3096630b700f34f570d71840754f1750 231 SUPERFAMILY SSF52540 3 225 9.22E-28 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0539 3096630b700f34f570d71840754f1750 231 Pfam PF03029 Conserved hypothetical ATP binding protein 5 227 8.4E-57 T 31-10-2018 IPR004130 GPN-loop GTPase AF_0959 7122da03eeac1c44b27bf0d9a460883c 212 SUPERFAMILY SSF52540 2 210 1.5E-58 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0959 7122da03eeac1c44b27bf0d9a460883c 212 ProSitePatterns PS00211 ABC transporters family signature. 132 146 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_0959 7122da03eeac1c44b27bf0d9a460883c 212 Gene3D G3DSA:3.40.50.300 1 212 7.4E-60 T 31-10-2018 AF_0959 7122da03eeac1c44b27bf0d9a460883c 212 SMART SM00382 24 210 8.1E-12 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0959 7122da03eeac1c44b27bf0d9a460883c 212 Pfam PF00005 ABC transporter 25 159 7.4E-31 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_0792 4d4ff5acbabc270c52e276f4c12f23a2 256 Gene3D G3DSA:3.20.20.410 19 252 1.3E-40 T 31-10-2018 IPR036520 UPF0759 superfamily AF_0792 4d4ff5acbabc270c52e276f4c12f23a2 256 SUPERFAMILY SSF117396 25 250 7.85E-44 T 31-10-2018 IPR036520 UPF0759 superfamily AF_0792 4d4ff5acbabc270c52e276f4c12f23a2 256 Pfam PF01904 Protein of unknown function DUF72 38 247 5.7E-33 T 31-10-2018 IPR002763 Protein of unknown function DUF72 AF_1095 67b1e26555b23db80f45614f751d9cc8 62 SUPERFAMILY SSF141694 1 57 3.14E-16 T 31-10-2018 AF_1095 67b1e26555b23db80f45614f751d9cc8 62 Pfam PF01954 Protein of unknown function DUF104 1 59 2.1E-24 T 31-10-2018 IPR008203 Uncharacterised protein family UPF0165 AF_1095 67b1e26555b23db80f45614f751d9cc8 62 Gene3D G3DSA:4.10.1150.10 1 61 3.0E-19 T 31-10-2018 IPR024069 AF2212-like domain superfamily AF_1296 a44c17416a7404ee856370eeea60d16d 174 Pfam PF00011 Hsp20/alpha crystallin family 89 173 1.4E-11 T 31-10-2018 IPR002068 Alpha crystallin/Hsp20 domain AF_1296 a44c17416a7404ee856370eeea60d16d 174 Gene3D G3DSA:2.60.40.790 80 163 3.2E-24 T 31-10-2018 IPR008978 HSP20-like chaperone AF_1296 a44c17416a7404ee856370eeea60d16d 174 SUPERFAMILY SSF49764 83 174 1.83E-23 T 31-10-2018 IPR008978 HSP20-like chaperone AF_0377 dcd2cd7565feb38e2cba7912cd12d5f6 452 Gene3D G3DSA:3.20.20.20 127 437 1.9E-121 T 31-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AF_0377 dcd2cd7565feb38e2cba7912cd12d5f6 452 Hamap MF_01135 Acetyl-CoA decarbonylase/synthase complex subunit delta [cdhD]. 24 450 54.969 T 31-10-2018 IPR004486 CO dehydrogenase/acetyl-CoA synthase delta subunit GO:0006730 AF_0377 dcd2cd7565feb38e2cba7912cd12d5f6 452 Pfam PF03599 CO dehydrogenase/acetyl-CoA synthase delta subunit 128 380 1.7E-85 T 31-10-2018 IPR016041 CO dehydrogenase/acetyl-CoA synthase delta subunit, TIM barrel AF_0377 dcd2cd7565feb38e2cba7912cd12d5f6 452 TIGRFAM TIGR00381 cdhD: CO dehydrogenase/acetyl-CoA synthase, delta subunit 51 448 1.1E-212 T 31-10-2018 IPR004486 CO dehydrogenase/acetyl-CoA synthase delta subunit GO:0006730 AF_0377 dcd2cd7565feb38e2cba7912cd12d5f6 452 SUPERFAMILY SSF51717 182 371 4.19E-20 T 31-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AF_1954 49a5d650a763ff2a2b7288f492c3081e 453 SUPERFAMILY SSF75304 4 443 5.89E-137 T 31-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AF_1954 49a5d650a763ff2a2b7288f492c3081e 453 Gene3D G3DSA:3.90.1300.10 1 452 2.3E-146 T 31-10-2018 IPR036928 Amidase signature (AS) superfamily KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AF_1954 49a5d650a763ff2a2b7288f492c3081e 453 Pfam PF01425 Amidase 20 434 1.2E-132 T 31-10-2018 IPR023631 Amidase signature domain KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921 AF_1954 49a5d650a763ff2a2b7288f492c3081e 453 ProSitePatterns PS00571 Amidases signature. 140 171 - T 31-10-2018 IPR020556 Amidase, conserved site KEGG: 00970+6.3.5.7|MetaCyc: PWY-5921|Reactome: R-HSA-2142753 AF_1911 b30b006004c12b82d851a38f257094e6 51 Pfam PF00253 Ribosomal protein S14p/S29e 3 50 5.9E-14 T 31-10-2018 IPR001209 Ribosomal protein S14 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_1911 b30b006004c12b82d851a38f257094e6 51 SUPERFAMILY SSF57716 4 49 2.92E-7 T 31-10-2018 AF_1911 b30b006004c12b82d851a38f257094e6 51 Hamap MF_01364_A 30S ribosomal protein S14 type Z [rpsZ]. 1 50 18.152 T 31-10-2018 IPR023676 Ribosomal protein S14, type Z, archaeal GO:0003723|GO:0003735|GO:0006412|GO:0015935 AF_1911 b30b006004c12b82d851a38f257094e6 51 Gene3D G3DSA:4.10.830.10 1 51 3.0E-22 T 31-10-2018 AF_1911 b30b006004c12b82d851a38f257094e6 51 ProSitePatterns PS00527 Ribosomal protein S14 signature. 17 39 - T 31-10-2018 IPR018271 Ribosomal protein S14, conserved site GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2050 1da539dbcf29066b67e25250ce78642c 126 SUPERFAMILY SSF111038 2 125 9.68E-44 T 31-10-2018 IPR035917 YjbQ-like superfamily AF_2050 1da539dbcf29066b67e25250ce78642c 126 Gene3D G3DSA:2.60.120.460 1 126 2.5E-48 T 31-10-2018 IPR035917 YjbQ-like superfamily AF_2050 1da539dbcf29066b67e25250ce78642c 126 PIRSF PIRSF004681 1 126 6.5E-40 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 AF_2050 1da539dbcf29066b67e25250ce78642c 126 ProSitePatterns PS01314 Uncharacterized protein family UPF0047 signature. 90 108 - T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 AF_2050 1da539dbcf29066b67e25250ce78642c 126 Pfam PF01894 Uncharacterised protein family UPF0047 15 124 8.2E-38 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 AF_2050 1da539dbcf29066b67e25250ce78642c 126 TIGRFAM TIGR00149 TIGR00149_YjbQ: secondary thiamine-phosphate synthase enzyme 1 125 4.5E-52 T 31-10-2018 IPR001602 Uncharacterised protein family UPF0047 AF_1077 63b97bf8fa3f493424fc523f8e8ddb38 130 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 3 129 10.735 T 31-10-2018 IPR022907 VapC family GO:0004540 AF_1077 63b97bf8fa3f493424fc523f8e8ddb38 130 Pfam PF01850 PIN domain 3 125 5.8E-30 T 31-10-2018 IPR002716 PIN domain AF_1077 63b97bf8fa3f493424fc523f8e8ddb38 130 Gene3D G3DSA:3.40.50.1010 2 129 6.1E-17 T 31-10-2018 AF_1077 63b97bf8fa3f493424fc523f8e8ddb38 130 SMART SM00670 1 121 6.1E-25 T 31-10-2018 IPR002716 PIN domain AF_1077 63b97bf8fa3f493424fc523f8e8ddb38 130 SUPERFAMILY SSF88723 1 124 3.92E-23 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_1659 e7a6ca4f956a1d856de5bed552a33034 250 Pfam PF12389 Camelysin metallo-endopeptidase 11 65 2.4E-6 T 31-10-2018 IPR022121 Peptidase M73, camelysin AF_1659 e7a6ca4f956a1d856de5bed552a33034 250 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 8 39 1.2E-6 T 31-10-2018 IPR023833 Signal peptide, camelysin AF_1926 d320f31810b78456c4801cd364c7fc1f 256 SUPERFAMILY SSF75217 2 248 9.59E-47 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases AF_1926 d320f31810b78456c4801cd364c7fc1f 256 Gene3D G3DSA:3.40.1280.10 4 247 2.2E-73 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AF_1926 d320f31810b78456c4801cd364c7fc1f 256 SUPERFAMILY SSF50249 89 159 1.03E-14 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_1926 d320f31810b78456c4801cd364c7fc1f 256 Pfam PF02598 Putative RNA methyltransferase 2 245 8.3E-56 T 31-10-2018 IPR003750 Putative RNA methyltransferase AF_1926 d320f31810b78456c4801cd364c7fc1f 256 Gene3D G3DSA:2.40.50.140 95 156 2.2E-73 T 31-10-2018 AF_1871 b466a5de14babdd37285d7a080f435a4 319 TIGRFAM TIGR02583 DevR_archaea: CRISPR-associated protein Cas7/Csa2, subtype I-A/APERN 8 288 1.7E-112 T 31-10-2018 IPR002764 CRISPR-associated protein Cas7/Cst2/DevR, subtype I-a/Apern AF_1871 b466a5de14babdd37285d7a080f435a4 319 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 9 266 2.2E-62 T 31-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR AF_1871 b466a5de14babdd37285d7a080f435a4 319 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 11 280 2.1E-86 T 31-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR AF_0356 3d782e49e8c859fc3fc0b4d68e00d5f2 250 ProSitePatterns PS00584 pfkB family of carbohydrate kinases signature 2. 199 212 - T 31-10-2018 IPR002173 Carbohydrate/puine kinase, PfkB, conserved site GO:0016773 AF_0356 3d782e49e8c859fc3fc0b4d68e00d5f2 250 Pfam PF00294 pfkB family carbohydrate kinase 1 246 1.3E-52 T 31-10-2018 IPR011611 Carbohydrate kinase PfkB AF_0356 3d782e49e8c859fc3fc0b4d68e00d5f2 250 Gene3D G3DSA:3.40.1190.20 1 249 1.2E-67 T 31-10-2018 IPR029056 Ribokinase-like AF_0356 3d782e49e8c859fc3fc0b4d68e00d5f2 250 SUPERFAMILY SSF53613 1 246 1.54E-63 T 31-10-2018 IPR029056 Ribokinase-like AF_1420 fc62f2e466b2b98252b7873ab181bffa 249 Gene3D G3DSA:3.30.479.30 46 177 7.8E-53 T 31-10-2018 AF_1420 fc62f2e466b2b98252b7873ab181bffa 249 Pfam PF01145 SPFH domain / Band 7 family 22 191 1.2E-38 T 31-10-2018 IPR001107 Band 7 domain AF_1420 fc62f2e466b2b98252b7873ab181bffa 249 PRINTS PR00721 Stomatin signature 170 191 1.5E-73 T 31-10-2018 IPR001972 Stomatin family GO:0016020 AF_1420 fc62f2e466b2b98252b7873ab181bffa 249 PRINTS PR00721 Stomatin signature 127 150 1.5E-73 T 31-10-2018 IPR001972 Stomatin family GO:0016020 AF_1420 fc62f2e466b2b98252b7873ab181bffa 249 PRINTS PR00721 Stomatin signature 72 93 1.5E-73 T 31-10-2018 IPR001972 Stomatin family GO:0016020 AF_1420 fc62f2e466b2b98252b7873ab181bffa 249 PRINTS PR00721 Stomatin signature 25 47 1.5E-73 T 31-10-2018 IPR001972 Stomatin family GO:0016020 AF_1420 fc62f2e466b2b98252b7873ab181bffa 249 PRINTS PR00721 Stomatin signature 107 124 1.5E-73 T 31-10-2018 IPR001972 Stomatin family GO:0016020 AF_1420 fc62f2e466b2b98252b7873ab181bffa 249 PRINTS PR00721 Stomatin signature 195 218 1.5E-73 T 31-10-2018 IPR001972 Stomatin family GO:0016020 AF_1420 fc62f2e466b2b98252b7873ab181bffa 249 PRINTS PR00721 Stomatin signature 151 169 1.5E-73 T 31-10-2018 IPR001972 Stomatin family GO:0016020 AF_1420 fc62f2e466b2b98252b7873ab181bffa 249 SUPERFAMILY SSF117892 49 182 3.79E-46 T 31-10-2018 IPR036013 Band 7/SPFH domain superfamily AF_1420 fc62f2e466b2b98252b7873ab181bffa 249 SMART SM00244 18 175 1.3E-73 T 31-10-2018 IPR001107 Band 7 domain AF_1420 fc62f2e466b2b98252b7873ab181bffa 249 ProSitePatterns PS01270 Band 7 protein family signature. 131 159 - T 31-10-2018 IPR018080 Band 7/stomatin-like, conserved site AF_1321 3ba69a70181f2fb6d1a915ebfa73c983 287 PIRSF PIRSF004976 1 287 3.7E-84 T 31-10-2018 IPR035107 tRNA thiolation protein, TtcA/Ctu1 type GO:0008033 Reactome: R-HSA-6782315 AF_1321 3ba69a70181f2fb6d1a915ebfa73c983 287 Gene3D G3DSA:3.40.50.620 1 287 4.5E-64 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_1321 3ba69a70181f2fb6d1a915ebfa73c983 287 Pfam PF01171 PP-loop family 50 205 1.1E-11 T 31-10-2018 IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal Reactome: R-HSA-6782315 AF_1321 3ba69a70181f2fb6d1a915ebfa73c983 287 SUPERFAMILY SSF52402 25 227 5.95E-38 T 31-10-2018 AF_1017 4a36543870418bd4d3301a78605da7fd 377 Pfam PF12704 MacB-like periplasmic core domain 20 218 1.9E-24 T 31-10-2018 IPR025857 MacB-like periplasmic core domain AF_1017 4a36543870418bd4d3301a78605da7fd 377 Pfam PF02687 FtsX-like permease family 278 370 2.4E-13 T 31-10-2018 IPR003838 ABC transporter permease protein domain GO:0016020 AF_0351 82c763c20d6c2832cc9922ede4fb83db 226 Pfam PF06745 KaiC 3 223 1.5E-65 T 31-10-2018 IPR014774 KaiC-like domain AF_0351 82c763c20d6c2832cc9922ede4fb83db 226 TIGRFAM TIGR03880 KaiC_arch_3: KaiC domain protein, AF_0351 family 5 226 2.9E-100 T 31-10-2018 IPR022420 Circadian clock protein, KaiC, archaea AF_0351 82c763c20d6c2832cc9922ede4fb83db 226 SUPERFAMILY SSF52540 2 222 2.12E-40 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0351 82c763c20d6c2832cc9922ede4fb83db 226 Gene3D G3DSA:3.40.50.300 1 225 5.5E-51 T 31-10-2018 AF_2213 b593356fdf954c30690e812825621cff 72 Pfam PF01850 PIN domain 11 67 9.3E-17 T 31-10-2018 IPR002716 PIN domain AF_2213 b593356fdf954c30690e812825621cff 72 SUPERFAMILY SSF88723 5 66 1.85E-10 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_2213 b593356fdf954c30690e812825621cff 72 Gene3D G3DSA:3.40.50.1010 2 70 6.6E-8 T 31-10-2018 AF_2320 cef6c2e893a97f22e57ea9123a9eaa19 211 SMART SM01397 5 197 2.6E-107 T 31-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2320 cef6c2e893a97f22e57ea9123a9eaa19 211 Pfam PF01015 Ribosomal S3Ae family 7 197 8.1E-67 T 31-10-2018 IPR001593 Ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2320 cef6c2e893a97f22e57ea9123a9eaa19 211 ProSitePatterns PS01191 Ribosomal protein S3Ae signature. 44 56 - T 31-10-2018 IPR018281 Ribosomal protein S3Ae, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2320 cef6c2e893a97f22e57ea9123a9eaa19 211 Hamap MF_00359 30S ribosomal protein S3Ae [rps3ae]. 5 197 36.26 T 31-10-2018 IPR030838 30S ribosomal protein S3Ae GO:0003735|GO:0005840|GO:0006412 AF_0223 854fc902b660252caee6f6779d075617 380 SUPERFAMILY SSF53822 5 368 3.2E-55 T 31-10-2018 IPR028082 Periplasmic binding protein-like I AF_0223 854fc902b660252caee6f6779d075617 380 Gene3D G3DSA:3.40.50.2300 5 348 6.8E-65 T 31-10-2018 AF_0223 854fc902b660252caee6f6779d075617 380 Pfam PF13458 Periplasmic binding protein 5 357 4.7E-40 T 31-10-2018 IPR028081 Leucine-binding protein domain AF_0223 854fc902b660252caee6f6779d075617 380 Gene3D G3DSA:3.40.50.2300 118 377 6.8E-65 T 31-10-2018 AF_1418 222d7c2a4faef848dc68696d154defc7 137 TIGRFAM TIGR00125 cyt_tran_rel: cytidyltransferase-like domain 1 62 4.7E-21 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AF_1418 222d7c2a4faef848dc68696d154defc7 137 Pfam PF01467 Cytidylyltransferase-like 1 129 1.5E-25 T 31-10-2018 IPR004821 Cytidyltransferase-like domain GO:0003824|GO:0009058 AF_1418 222d7c2a4faef848dc68696d154defc7 137 Gene3D G3DSA:3.40.50.620 1 116 1.9E-35 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_1418 222d7c2a4faef848dc68696d154defc7 137 SUPERFAMILY SSF52374 2 132 2.48E-24 T 31-10-2018 AF_1418 222d7c2a4faef848dc68696d154defc7 137 Hamap MF_02115 FAD synthase [ribL]. 1 135 32.821 T 31-10-2018 IPR024902 FAD synthase RibL GO:0003919|GO:0006747|GO:0046444 KEGG: 00740+2.7.7.2|MetaCyc: PWY-6167|MetaCyc: PWY-6168 AF_0994 6af73e51366a03b124b7d722c57f67c3 185 Pfam PF01966 HD domain 7 100 1.7E-18 T 31-10-2018 IPR006674 HD domain AF_0994 6af73e51366a03b124b7d722c57f67c3 185 SMART SM00471 1 110 3.6E-10 T 31-10-2018 IPR003607 HD/PDEase domain AF_0994 6af73e51366a03b124b7d722c57f67c3 185 SUPERFAMILY SSF109604 2 166 5.14E-55 T 31-10-2018 AF_0994 6af73e51366a03b124b7d722c57f67c3 185 Gene3D G3DSA:1.10.3210.50 1 183 1.7E-58 T 31-10-2018 AF_1553 31267774a983bea55be549d28055573d 216 SUPERFAMILY SSF56399 32 205 1.01E-47 T 31-10-2018 AF_1553 31267774a983bea55be549d28055573d 216 Hamap MF_00299 Probable RNA 2'-phosphotransferase [kptA]. 29 200 34.06 T 31-10-2018 IPR022928 RNA 2'-phosphotransferase KptA, putative GO:0016773 AF_1553 31267774a983bea55be549d28055573d 216 Gene3D G3DSA:3.20.170.30 120 208 9.2E-27 T 31-10-2018 AF_1553 31267774a983bea55be549d28055573d 216 Pfam PF01885 RNA 2'-phosphotransferase, Tpt1 / KptA family 30 185 1.1E-29 T 31-10-2018 IPR002745 Phosphotransferase KptA/Tpt1 GO:0006388|GO:0016772 AF_1553 31267774a983bea55be549d28055573d 216 Gene3D G3DSA:1.10.10.970 29 99 5.6E-21 T 31-10-2018 AF_2378 de963e5c15566bb3a9487b084d4b9343 144 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 104 1.9E-22 T 31-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis AF_2378 de963e5c15566bb3a9487b084d4b9343 144 Gene3D G3DSA:3.30.420.130 1 123 8.0E-31 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily AF_2378 de963e5c15566bb3a9487b084d4b9343 144 SUPERFAMILY SSF53146 1 121 1.19E-29 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily AF_0920 6a272f32e717e1e3b76a67a7fb8323cf 430 SUPERFAMILY SSF50249 3 103 1.03E-29 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0920 6a272f32e717e1e3b76a67a7fb8323cf 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 202 215 5.7E-23 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_0920 6a272f32e717e1e3b76a67a7fb8323cf 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 385 399 5.7E-23 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_0920 6a272f32e717e1e3b76a67a7fb8323cf 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 185 197 5.7E-23 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_0920 6a272f32e717e1e3b76a67a7fb8323cf 430 PRINTS PR01042 Aspartyl-tRNA synthetase signature 345 361 5.7E-23 T 31-10-2018 IPR002312 Aspartyl/Asparaginyl-tRNA synthetase, class IIb GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_0920 6a272f32e717e1e3b76a67a7fb8323cf 430 Gene3D G3DSA:3.30.930.10 105 430 4.9E-113 T 31-10-2018 AF_0920 6a272f32e717e1e3b76a67a7fb8323cf 430 Gene3D G3DSA:2.40.50.140 1 101 3.4E-30 T 31-10-2018 AF_0920 6a272f32e717e1e3b76a67a7fb8323cf 430 Pfam PF01336 OB-fold nucleic acid binding domain 17 96 3.6E-17 T 31-10-2018 IPR004365 OB-fold nucleic acid binding domain, AA-tRNA synthetase-type GO:0003676 AF_0920 6a272f32e717e1e3b76a67a7fb8323cf 430 TIGRFAM TIGR00458 aspS_nondisc: aspartate--tRNA(Asn) ligase 3 430 2.7E-239 T 31-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AF_0920 6a272f32e717e1e3b76a67a7fb8323cf 430 Pfam PF00152 tRNA synthetases class II (D, K and N) 116 424 2.6E-94 T 31-10-2018 IPR004364 Aminoacyl-tRNA synthetase, class II (D/K/N) GO:0000166|GO:0004812|GO:0005524|GO:0006418 AF_0920 6a272f32e717e1e3b76a67a7fb8323cf 430 Hamap MF_02075 Aspartate--tRNA(Asp) ligase [aspS]. 1 430 44.779 T 31-10-2018 IPR004523 Aspartate-tRNA synthetase, type 2 GO:0000166|GO:0004815|GO:0005524|GO:0005737|GO:0006422 Reactome: R-HSA-2408517|Reactome: R-HSA-379716 AF_0920 6a272f32e717e1e3b76a67a7fb8323cf 430 SUPERFAMILY SSF55681 115 425 2.3E-100 T 31-10-2018 AF_0008 8c858cbd355ea6be370091d38bc1e840 420 Gene3D G3DSA:1.20.1250.20 2 405 1.3E-35 T 31-10-2018 AF_0008 8c858cbd355ea6be370091d38bc1e840 420 SUPERFAMILY SSF103473 4 404 7.32E-40 T 31-10-2018 IPR036259 MFS transporter superfamily AF_0008 8c858cbd355ea6be370091d38bc1e840 420 Pfam PF07690 Major Facilitator Superfamily 13 267 3.0E-18 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AF_0911 9288ccb3e00625113f2393b5992a7d3c 65 Pfam PF00833 Ribosomal S17 1 60 1.4E-12 T 31-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0911 9288ccb3e00625113f2393b5992a7d3c 65 Hamap MF_00511 30S ribosomal protein S17e [rps17e]. 1 60 20.251 T 31-10-2018 IPR001210 Ribosomal protein S17e GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0911 9288ccb3e00625113f2393b5992a7d3c 65 SUPERFAMILY SSF116820 1 59 3.01E-21 T 31-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0911 9288ccb3e00625113f2393b5992a7d3c 65 ProSitePatterns PS00712 Ribosomal protein S17e signature. 41 56 - T 31-10-2018 IPR018273 Ribosomal protein S17e, conserved site GO:0003735|GO:0005622|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0911 9288ccb3e00625113f2393b5992a7d3c 65 Gene3D G3DSA:1.10.60.20 1 61 3.9E-25 T 31-10-2018 IPR036401 Ribosomal protein S17e-like superfamily GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0111 7b6d6d32028d90babfd577b38c4dfea5 299 Pfam PF03444 Winged helix-turn-helix transcription repressor, HrcA DNA-binding 5 82 2.4E-37 T 31-10-2018 IPR005104 Winged helix-turn-helix transcription repressor, HrcA DNA-binding domain GO:0003677|GO:0006355 AF_0111 7b6d6d32028d90babfd577b38c4dfea5 299 Gene3D G3DSA:1.10.10.10 12 103 1.2E-8 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0111 7b6d6d32028d90babfd577b38c4dfea5 299 Pfam PF00571 CBS domain 177 231 5.3E-8 T 31-10-2018 IPR000644 CBS domain AF_0111 7b6d6d32028d90babfd577b38c4dfea5 299 Pfam PF00571 CBS domain 239 293 6.8E-12 T 31-10-2018 IPR000644 CBS domain AF_0111 7b6d6d32028d90babfd577b38c4dfea5 299 SUPERFAMILY SSF54631 167 296 2.07E-28 T 31-10-2018 AF_0111 7b6d6d32028d90babfd577b38c4dfea5 299 SMART SM00116 246 293 4.3E-7 T 31-10-2018 IPR000644 CBS domain AF_0111 7b6d6d32028d90babfd577b38c4dfea5 299 SMART SM00116 184 231 2.5E-4 T 31-10-2018 IPR000644 CBS domain AF_0111 7b6d6d32028d90babfd577b38c4dfea5 299 SUPERFAMILY SSF46785 14 134 1.1E-14 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0111 7b6d6d32028d90babfd577b38c4dfea5 299 Gene3D G3DSA:3.10.580.10 173 296 6.2E-29 T 31-10-2018 AF_0111 7b6d6d32028d90babfd577b38c4dfea5 299 PIRSF PIRSF005063 3 299 3.3E-123 T 31-10-2018 IPR016436 Uncharacterised conserved protein UCP005063, CBS-type AF_1958 92478deb1b5c4d1a6de2ade089e2d4ad 391 Pfam PF06050 2-hydroxyglutaryl-CoA dehydratase, D-component 35 390 2.2E-68 T 31-10-2018 IPR010327 FldB/FldC dehydratase alpha/beta subunit AF_1958 92478deb1b5c4d1a6de2ade089e2d4ad 391 Gene3D G3DSA:3.40.50.11890 26 169 5.0E-8 T 31-10-2018 AF_1958 92478deb1b5c4d1a6de2ade089e2d4ad 391 Gene3D G3DSA:3.40.50.11900 270 391 9.7E-11 T 31-10-2018 AF_1958 92478deb1b5c4d1a6de2ade089e2d4ad 391 Gene3D G3DSA:1.20.1270.370 25 205 5.0E-8 T 31-10-2018 AF_0849 7bf241c41630474b04c0bed65b7d6496 378 Gene3D G3DSA:3.30.1490.70 74 244 1.7E-59 T 31-10-2018 AF_0849 7bf241c41630474b04c0bed65b7d6496 378 Pfam PF09414 RNA ligase 89 237 5.1E-16 T 31-10-2018 IPR021122 RNA ligase domain, REL/Rln2 AF_0849 7bf241c41630474b04c0bed65b7d6496 378 TIGRFAM TIGR01209 TIGR01209: RNA ligase, Pab1020 family 15 377 2.1E-155 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family AF_0849 7bf241c41630474b04c0bed65b7d6496 378 Gene3D G3DSA:3.30.470.30 100 200 1.7E-59 T 31-10-2018 AF_0849 7bf241c41630474b04c0bed65b7d6496 378 Gene3D G3DSA:3.30.70.3350 248 374 3.9E-25 T 31-10-2018 AF_0849 7bf241c41630474b04c0bed65b7d6496 378 Gene3D G3DSA:3.30.70.3360 318 361 3.9E-25 T 31-10-2018 AF_0849 7bf241c41630474b04c0bed65b7d6496 378 SUPERFAMILY SSF56091 66 264 1.52E-37 T 31-10-2018 AF_0849 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 167 188 7.2E-98 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family AF_0849 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 222 235 7.2E-98 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family AF_0849 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 354 374 7.2E-98 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family AF_0849 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 295 309 7.2E-98 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family AF_0849 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 142 157 7.2E-98 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family AF_0849 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 112 127 7.2E-98 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family AF_0849 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 264 282 7.2E-98 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family AF_0849 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 240 253 7.2E-98 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family AF_0849 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 43 57 7.2E-98 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family AF_0849 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 68 86 7.2E-98 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family AF_0849 7bf241c41630474b04c0bed65b7d6496 378 PRINTS PR01048 Hypothetical protein Y414 family signature 91 104 7.2E-98 T 31-10-2018 IPR001072 RNA ligase, Pab1020 family AF_1322 5782bd1cbf38fbd73571e0230570b4e5 501 Pfam PF13180 PDZ domain 287 345 1.6E-9 T 31-10-2018 IPR001478 PDZ domain GO:0005515 AF_1322 5782bd1cbf38fbd73571e0230570b4e5 501 Pfam PF02163 Peptidase family M50 125 483 1.2E-21 T 31-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 AF_1322 5782bd1cbf38fbd73571e0230570b4e5 501 Gene3D G3DSA:2.30.42.10 265 351 6.1E-13 T 31-10-2018 AF_1322 5782bd1cbf38fbd73571e0230570b4e5 501 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 132 146 9.1E-14 T 31-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 AF_1322 5782bd1cbf38fbd73571e0230570b4e5 501 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 110 129 9.1E-14 T 31-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 AF_1322 5782bd1cbf38fbd73571e0230570b4e5 501 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 148 163 9.1E-14 T 31-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 AF_1322 5782bd1cbf38fbd73571e0230570b4e5 501 PRINTS PR01000 Sterol regulatory element binding protein site 2 protease (M50) signature 164 176 9.1E-14 T 31-10-2018 IPR001193 Membrane-bound transcription factor site-2 protease GO:0004222|GO:0006508|GO:0016020 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 AF_1322 5782bd1cbf38fbd73571e0230570b4e5 501 SUPERFAMILY SSF50156 288 363 1.0E-12 T 31-10-2018 IPR036034 PDZ superfamily GO:0005515 AF_1423 2ebe41799506eda7b4ebe9ccc48a4f8d 387 Pfam PF01966 HD domain 51 155 2.1E-14 T 31-10-2018 IPR006674 HD domain AF_1423 2ebe41799506eda7b4ebe9ccc48a4f8d 387 SUPERFAMILY SSF109604 2 373 5.73E-85 T 31-10-2018 AF_1423 2ebe41799506eda7b4ebe9ccc48a4f8d 387 Gene3D G3DSA:1.10.3210.10 2 264 8.7E-77 T 31-10-2018 AF_1423 2ebe41799506eda7b4ebe9ccc48a4f8d 387 SMART SM00471 47 163 1.6E-14 T 31-10-2018 IPR003607 HD/PDEase domain AF_0235 212241155f4be1faea95c926b0d6bc43 335 Gene3D G3DSA:3.30.2010.10 96 185 1.6E-18 T 31-10-2018 AF_0235 212241155f4be1faea95c926b0d6bc43 335 Hamap MF_00188 Protease HtpX [htpX]. 41 332 26.16 T 31-10-2018 IPR022919 Peptidase M48, protease HtpX, putative GO:0004222 AF_0235 212241155f4be1faea95c926b0d6bc43 335 Pfam PF01435 Peptidase family M48 103 332 2.5E-55 T 31-10-2018 IPR001915 Peptidase M48 GO:0004222|GO:0006508 AF_0788 58d51eb62eee87fc481dc891874cede7 308 Pfam PF00892 EamA-like transporter family 44 165 2.2E-23 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AF_0788 58d51eb62eee87fc481dc891874cede7 308 Pfam PF00892 EamA-like transporter family 172 305 1.1E-22 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AF_0788 58d51eb62eee87fc481dc891874cede7 308 SUPERFAMILY SSF103481 77 167 2.48E-12 T 31-10-2018 AF_0788 58d51eb62eee87fc481dc891874cede7 308 SUPERFAMILY SSF103481 212 306 4.05E-10 T 31-10-2018 AF_2110 1fbcc4d4262fac837f4037ea9c671c43 241 TIGRFAM TIGR00697 TIGR00697: conserved hypothetical integral membrane protein 26 230 2.1E-83 T 31-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 AF_2110 1fbcc4d4262fac837f4037ea9c671c43 241 Pfam PF02592 Putative vitamin uptake transporter 58 223 6.3E-54 T 31-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 AF_2110 1fbcc4d4262fac837f4037ea9c671c43 241 Hamap MF_02088 Probable queuosine precursor transporter. 26 231 17.314 T 31-10-2018 IPR003744 Queuosine precursor transporter GO:1990397 AF_0380 9fc972d4ba47889dbebfbca7c4b5e3c2 868 Gene3D G3DSA:2.60.40.3390 780 867 1.2E-34 T 31-10-2018 AF_0380 9fc972d4ba47889dbebfbca7c4b5e3c2 868 TIGRFAM TIGR04154 archaeo_STT3: oligosaccharyl transferase, archaeosortase A system-associated 15 861 1.2E-250 T 31-10-2018 IPR026410 Oligosaccharyl transferase, archaeal MetaCyc: PWY-7658|MetaCyc: PWY-7661 AF_0380 9fc972d4ba47889dbebfbca7c4b5e3c2 868 Pfam PF02516 Oligosaccharyl transferase STT3 subunit 18 493 6.2E-118 T 31-10-2018 IPR003674 Oligosaccharyl transferase, STT3 subunit GO:0004576|GO:0006486|GO:0016020 AF_0380 9fc972d4ba47889dbebfbca7c4b5e3c2 868 Gene3D G3DSA:3.40.50.12610 499 699 3.3E-194 T 31-10-2018 AF_0380 9fc972d4ba47889dbebfbca7c4b5e3c2 868 Gene3D G3DSA:1.20.58.1650 640 770 3.3E-194 T 31-10-2018 AF_1089 d4d706374e030edaa9dcd7054d5fc5e2 141 SMART SM00670 2 117 4.2E-14 T 31-10-2018 IPR002716 PIN domain AF_1089 d4d706374e030edaa9dcd7054d5fc5e2 141 Gene3D G3DSA:3.40.50.1010 2 124 1.7E-10 T 31-10-2018 AF_1089 d4d706374e030edaa9dcd7054d5fc5e2 141 SUPERFAMILY SSF88723 1 139 7.57E-19 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_1089 d4d706374e030edaa9dcd7054d5fc5e2 141 Pfam PF01850 PIN domain 5 120 1.1E-13 T 31-10-2018 IPR002716 PIN domain AF_0831 7e58fd4b0ce18ac2d4a6d2aa4c9b1b74 190 Gene3D G3DSA:1.20.1260.10 1 144 2.5E-51 T 31-10-2018 IPR012347 Ferritin-like AF_0831 7e58fd4b0ce18ac2d4a6d2aa4c9b1b74 190 SUPERFAMILY SSF57802 146 184 4.89E-11 T 31-10-2018 AF_0831 7e58fd4b0ce18ac2d4a6d2aa4c9b1b74 190 Pfam PF02915 Rubrerythrin 5 137 4.3E-38 T 31-10-2018 IPR003251 Rubrerythrin GO:0016491|GO:0046872|GO:0055114 AF_0831 7e58fd4b0ce18ac2d4a6d2aa4c9b1b74 190 Gene3D G3DSA:2.20.28.10 145 186 1.4E-16 T 31-10-2018 AF_0831 7e58fd4b0ce18ac2d4a6d2aa4c9b1b74 190 SUPERFAMILY SSF47240 3 145 7.69E-37 T 31-10-2018 IPR009078 Ferritin-like superfamily AF_2307 d5c42c975a3b8876168fe46176162049 365 SUPERFAMILY SSF55931 1 341 3.92E-47 T 31-10-2018 IPR014746 Glutamine synthetase/guanido kinase, catalytic domain GO:0003824 AF_2307 d5c42c975a3b8876168fe46176162049 365 Gene3D G3DSA:3.30.590.20 1 349 1.4E-56 T 31-10-2018 AF_2307 d5c42c975a3b8876168fe46176162049 365 Pfam PF04107 Glutamate-cysteine ligase family 2(GCS2) 13 284 7.7E-73 T 31-10-2018 IPR006336 Glutamate--cysteine ligase, GCS2 GO:0004357|GO:0042398 KEGG: 00270+6.3.2.2|KEGG: 00480+6.3.2.2|MetaCyc: PWY-6840|MetaCyc: PWY-7255 AF_0276 3e0bfc76d6548b5d198b5eff847a4de2 337 Hamap MF_01086 UPF0284 protein . 1 337 122.887 T 31-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative AF_0276 3e0bfc76d6548b5d198b5eff847a4de2 337 SUPERFAMILY SSF52733 35 333 3.92E-52 T 31-10-2018 IPR036087 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like superfamily GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 AF_0276 3e0bfc76d6548b5d198b5eff847a4de2 337 Pfam PF02277 Phosphoribosyltransferase 93 243 2.3E-12 T 31-10-2018 IPR003200 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like GO:0008939|GO:0009236 KEGG: 00860+2.4.2.21|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970 AF_0276 3e0bfc76d6548b5d198b5eff847a4de2 337 TIGRFAM TIGR00303 TIGR00303: TIGR00303 family protein 13 329 1.1E-147 T 31-10-2018 IPR002805 Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative AF_0276 3e0bfc76d6548b5d198b5eff847a4de2 337 Gene3D G3DSA:3.40.50.10210 15 337 7.9E-115 T 31-10-2018 AF_1061 e0d8591821a0f3d42c79eec07c016cff 304 Gene3D G3DSA:3.30.1490.350 124 164 8.3E-64 T 31-10-2018 AF_1061 e0d8591821a0f3d42c79eec07c016cff 304 Pfam PF02655 ATP-grasp domain 108 251 1.3E-43 T 31-10-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 AF_1061 e0d8591821a0f3d42c79eec07c016cff 304 Gene3D G3DSA:3.40.50.11770 1 97 2.7E-53 T 31-10-2018 AF_1061 e0d8591821a0f3d42c79eec07c016cff 304 SUPERFAMILY SSF56059 122 267 9.12E-19 T 31-10-2018 AF_1061 e0d8591821a0f3d42c79eec07c016cff 304 PIRSF PIRSF016766 1 304 2.3E-101 T 31-10-2018 IPR024710 Tyramine--L-glutamate ligase KEGG: 00680+6.3.4.24|MetaCyc: PWY-5254 AF_1061 e0d8591821a0f3d42c79eec07c016cff 304 Gene3D G3DSA:3.30.470.20 103 265 8.3E-64 T 31-10-2018 AF_0378 091d249d3003f179d12b530b804657ac 258 PIRSF PIRSF005647 2 255 5.3E-85 T 31-10-2018 IPR014433 Nickel insertion ATPase/GTPase (CO dehydrogenase maturation factor), CooC type AF_0378 091d249d3003f179d12b530b804657ac 258 Pfam PF01656 CobQ/CobB/MinD/ParA nucleotide binding domain 3 230 5.1E-24 T 31-10-2018 IPR002586 CobQ/CobB/MinD/ParA nucleotide binding domain AF_0378 091d249d3003f179d12b530b804657ac 258 SUPERFAMILY SSF52540 1 252 9.9E-41 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0378 091d249d3003f179d12b530b804657ac 258 Gene3D G3DSA:3.40.50.300 2 252 1.4E-56 T 31-10-2018 AF_0272 970e03349a0f16dd92a065947ae7a79d 143 Pfam PF07849 Protein of unknown function (DUF1641) 102 140 5.3E-16 T 31-10-2018 IPR012440 Protein of unknown function DUF1641 AF_1550 4f8468947fccd052eab4414f8d9d3635 213 SUPERFAMILY SSF89550 10 196 1.96E-33 T 31-10-2018 IPR016195 Polymerase/histidinol phosphatase-like GO:0003824 Reactome: R-HSA-6784531|Reactome: R-HSA-6791226 AF_1550 4f8468947fccd052eab4414f8d9d3635 213 Pfam PF02811 PHP domain 3 98 1.3E-6 T 31-10-2018 IPR004013 PHP domain GO:0003824 AF_1550 4f8468947fccd052eab4414f8d9d3635 213 Gene3D G3DSA:3.20.20.140 1 213 5.9E-26 T 31-10-2018 AF_1550 4f8468947fccd052eab4414f8d9d3635 213 SMART SM00481 2 74 2.6E-21 T 31-10-2018 IPR003141 Polymerase/histidinol phosphatase, N-terminal AF_1092 eb21b0599ef88d353b18dc8a449a6fb0 61 Pfam PF01954 Protein of unknown function DUF104 1 54 4.4E-21 T 31-10-2018 IPR008203 Uncharacterised protein family UPF0165 AF_1092 eb21b0599ef88d353b18dc8a449a6fb0 61 SUPERFAMILY SSF141694 1 57 7.59E-17 T 31-10-2018 AF_1092 eb21b0599ef88d353b18dc8a449a6fb0 61 Gene3D G3DSA:4.10.1150.10 1 61 1.0E-19 T 31-10-2018 IPR024069 AF2212-like domain superfamily AF_1789 65c432dfc3b55343fa12e06dddad2a2e 203 SUPERFAMILY SSF53271 3 134 8.7E-21 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like AF_1789 65c432dfc3b55343fa12e06dddad2a2e 203 Gene3D G3DSA:3.40.50.2020 2 156 2.5E-25 T 31-10-2018 AF_1314 cb8fdf35b67cde768d8d219cb2de4ba5 215 SUPERFAMILY SSF51905 3 38 5.37E-5 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1314 cb8fdf35b67cde768d8d219cb2de4ba5 215 Gene3D G3DSA:3.40.50.720 3 58 4.4E-5 T 31-10-2018 AF_2205 ed97d921e0c5fb9802aec52d56e6cdd8 508 SUPERFAMILY SSF82171 99 494 9.81E-10 T 31-10-2018 AF_1142 81c693fa5a441f5a6b8e3d60ee32de31 241 Pfam PF12804 MobA-like NTP transferase domain 3 118 3.7E-16 T 31-10-2018 IPR025877 MobA-like NTP transferase AF_1142 81c693fa5a441f5a6b8e3d60ee32de31 241 Gene3D G3DSA:3.90.550.10 1 240 1.5E-51 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_1142 81c693fa5a441f5a6b8e3d60ee32de31 241 SUPERFAMILY SSF53448 1 235 2.03E-44 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0177 0475ecc572072534e60ac6d2ebf627d8 189 Pfam PF02663 FmdE, Molybdenum formylmethanofuran dehydrogenase operon 14 128 2.9E-26 T 31-10-2018 IPR003814 Formylmethanofuran dehydrogenase, subunit E domain AF_0177 0475ecc572072534e60ac6d2ebf627d8 189 Gene3D G3DSA:3.30.1330.130 1 154 5.8E-36 T 31-10-2018 AF_0177 0475ecc572072534e60ac6d2ebf627d8 189 SUPERFAMILY SSF143555 4 147 6.28E-38 T 31-10-2018 AF_1036 08d045bdd221110e060b8252fe2149d8 282 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 17 97 5.4E-9 T 31-10-2018 IPR000014 PAS domain AF_1036 08d045bdd221110e060b8252fe2149d8 282 SMART SM00091 17 80 4.0E-6 T 31-10-2018 IPR000014 PAS domain AF_1036 08d045bdd221110e060b8252fe2149d8 282 Pfam PF08448 PAS fold 23 108 8.3E-9 T 31-10-2018 IPR013656 PAS fold-4 AF_1036 08d045bdd221110e060b8252fe2149d8 282 SUPERFAMILY SSF55785 6 109 1.08E-11 T 31-10-2018 IPR035965 PAS domain superfamily AF_1036 08d045bdd221110e060b8252fe2149d8 282 Gene3D G3DSA:3.30.450.20 24 129 5.4E-10 T 31-10-2018 AF_0053 0a4120b7a93848a7e40e4078a4675ec3 235 Pfam PF02163 Peptidase family M50 111 174 1.1E-8 T 31-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 AF_0880 e0273d4fc0555bfd97e8bb1089a51259 53 SUPERFAMILY SSF57802 1 53 7.07E-25 T 31-10-2018 AF_0880 e0273d4fc0555bfd97e8bb1089a51259 53 PIRSF PIRSF000071 1 53 1.4E-29 T 31-10-2018 IPR024922 Rubredoxin GO:0005506|GO:0009055 AF_0880 e0273d4fc0555bfd97e8bb1089a51259 53 Pfam PF00301 Rubredoxin 3 49 1.4E-26 T 31-10-2018 IPR024935 Rubredoxin domain GO:0005506 AF_0880 e0273d4fc0555bfd97e8bb1089a51259 53 PRINTS PR00163 Rubredoxin signature 3 19 7.5E-14 T 31-10-2018 IPR024935 Rubredoxin domain GO:0005506 AF_0880 e0273d4fc0555bfd97e8bb1089a51259 53 PRINTS PR00163 Rubredoxin signature 33 49 7.5E-14 T 31-10-2018 IPR024935 Rubredoxin domain GO:0005506 AF_0880 e0273d4fc0555bfd97e8bb1089a51259 53 Gene3D G3DSA:2.20.28.10 1 53 1.1E-29 T 31-10-2018 AF_0880 e0273d4fc0555bfd97e8bb1089a51259 53 ProSitePatterns PS00202 Rubredoxin signature. 33 43 - T 31-10-2018 IPR018527 Rubredoxin, iron-binding site GO:0046872 AF_0699 d1f26d0b6a7afdf62cc207fb5ae33e7e 438 Pfam PF02272 DHHA1 domain 324 432 1.9E-19 T 31-10-2018 IPR003156 DHHA1 domain GO:0003676 KEGG: 00970+6.1.1.7|Reactome: R-HSA-379716 AF_0699 d1f26d0b6a7afdf62cc207fb5ae33e7e 438 SUPERFAMILY SSF64182 11 436 8.24E-57 T 31-10-2018 IPR038763 DHH phosphoesterase superfamily AF_0699 d1f26d0b6a7afdf62cc207fb5ae33e7e 438 Gene3D G3DSA:3.90.1640.30 3 192 1.1E-17 T 31-10-2018 AF_0699 d1f26d0b6a7afdf62cc207fb5ae33e7e 438 Gene3D G3DSA:3.10.310.30 344 436 4.3E-5 T 31-10-2018 AF_1052 4c0fcba5c0eb0ddcce740ce1bbef8234 162 ProDom PD095203 PRECURSOR SIGNAL MA3079 MM0320 AF1052 MA3059 28 161 5.0E-74 T 31-10-2018 AF_1052 4c0fcba5c0eb0ddcce740ce1bbef8234 162 Pfam PF01917 Archaebacterial flagellin 3 157 6.2E-23 T 31-10-2018 IPR002774 Flagellin, archaea GO:0005198|GO:0006928 AF_2323 0722d171caaa6d36cfba4d104ffc27c9 231 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 1 225 2.7E-85 T 31-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 AF_2323 0722d171caaa6d36cfba4d104ffc27c9 231 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 231 23.684 T 31-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 AF_2323 0722d171caaa6d36cfba4d104ffc27c9 231 Pfam PF02654 Cobalamin-5-phosphate synthase 8 222 1.1E-35 T 31-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 AF_1612 a490b1cec81dac9b987ff14060cb4d3e 736 SUPERFAMILY SSF52402 470 598 2.34E-20 T 31-10-2018 AF_1612 a490b1cec81dac9b987ff14060cb4d3e 736 Gene3D G3DSA:3.40.50.620 605 729 1.5E-9 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_1612 a490b1cec81dac9b987ff14060cb4d3e 736 PRINTS PR01438 Universal stress protein signature 558 570 1.1E-5 T 31-10-2018 IPR006015 Universal stress protein A AF_1612 a490b1cec81dac9b987ff14060cb4d3e 736 PRINTS PR01438 Universal stress protein signature 576 598 1.1E-5 T 31-10-2018 IPR006015 Universal stress protein A AF_1612 a490b1cec81dac9b987ff14060cb4d3e 736 TIGRFAM TIGR00909 2A0306: amino acid transporter 7 443 3.9E-171 T 31-10-2018 IPR004758 Amino acid transporter AF_1612 a490b1cec81dac9b987ff14060cb4d3e 736 Gene3D G3DSA:3.40.50.620 468 600 6.3E-16 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_1612 a490b1cec81dac9b987ff14060cb4d3e 736 Gene3D G3DSA:1.20.1740.10 6 467 9.8E-110 T 31-10-2018 AF_1612 a490b1cec81dac9b987ff14060cb4d3e 736 SUPERFAMILY SSF52402 607 728 4.35E-11 T 31-10-2018 AF_1612 a490b1cec81dac9b987ff14060cb4d3e 736 Pfam PF13520 Amino acid permease 11 423 2.1E-48 T 31-10-2018 IPR002293 Amino acid/polyamine transporter I GO:0016020|GO:0022857|GO:0055085 AF_1612 a490b1cec81dac9b987ff14060cb4d3e 736 Pfam PF00582 Universal stress protein family 471 598 8.7E-21 T 31-10-2018 IPR006016 UspA AF_2247 7536ff313d2cdb8b072ee32e45ad2f13 349 Pfam PF03773 Predicted permease 8 345 7.9E-92 T 31-10-2018 IPR005524 Predicted permease DUF318 AF_1559 0b0457f371722ea0daacc3889991d9a0 224 Pfam PF02616 Segregation and condensation protein ScpA 1 222 1.3E-19 T 31-10-2018 IPR003768 Segregation and condensation protein A AF_1964 ecd356b6415dd75973f178e0e525870b 162 Gene3D G3DSA:3.40.1260.10 51 160 1.2E-13 T 31-10-2018 IPR027396 DsrEFH-like AF_1964 ecd356b6415dd75973f178e0e525870b 162 SUPERFAMILY SSF75169 54 136 5.1E-5 T 31-10-2018 IPR027396 DsrEFH-like AF_2079 6ca48d7430eacd2e25fc10c0191f99d8 152 Pfam PF06510 Protein of unknown function (DUF1102) 35 148 6.1E-26 T 31-10-2018 IPR009482 Protein of unknown function DUF1102 AF_1928 a1c316350f7ee45171938d59399f4058 122 SUPERFAMILY SSF50692 7 115 2.68E-21 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AF_1928 a1c316350f7ee45171938d59399f4058 122 Gene3D G3DSA:2.40.40.20 1 122 9.2E-53 T 31-10-2018 AF_1928 a1c316350f7ee45171938d59399f4058 122 Pfam PF01568 Molydopterin dinucleotide binding domain 6 101 2.6E-19 T 31-10-2018 IPR006657 Molybdopterin dinucleotide-binding domain GO:0016491|GO:0043546|GO:0055114 AF_1928 a1c316350f7ee45171938d59399f4058 122 PIRSF PIRSF015873 2 122 5.3E-53 T 31-10-2018 IPR012040 Formylmethanofuran dehydrogenase, subunit D AF_1143 3175efc055ff0d0deeedc57f8f008abd 141 ProSitePatterns PS00379 CDP-alcohol phosphatidyltransferases signature. 14 36 - T 31-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AF_1143 3175efc055ff0d0deeedc57f8f008abd 141 Gene3D G3DSA:1.20.120.1760 1 141 7.6E-35 T 31-10-2018 AF_2422 9db6dcb097eb395b0dbbead3c0645b34 162 SUPERFAMILY SSF103165 1 160 9.16E-56 T 31-10-2018 IPR036902 Ta1353-like superfamily AF_2422 9db6dcb097eb395b0dbbead3c0645b34 162 Pfam PF04008 Adenosine specific kinase 6 160 8.1E-58 T 31-10-2018 IPR007153 Adenosine specific kinase AF_2422 9db6dcb097eb395b0dbbead3c0645b34 162 Gene3D G3DSA:3.40.1520.10 1 162 4.8E-63 T 31-10-2018 IPR036902 Ta1353-like superfamily AF_1010 18cb845923ddf8e6d84e5ec5ad2414ab 60 Gene3D G3DSA:3.30.70.20 2 58 2.4E-12 T 31-10-2018 AF_1010 18cb845923ddf8e6d84e5ec5ad2414ab 60 Pfam PF13187 4Fe-4S dicluster domain 9 54 8.8E-9 T 31-10-2018 IPR017896 4Fe-4S ferredoxin-type, iron-sulphur binding domain AF_1010 18cb845923ddf8e6d84e5ec5ad2414ab 60 SUPERFAMILY SSF54862 1 57 7.71E-15 T 31-10-2018 AF_1068 ea3d21d6d6b1d9e00e7ca111641bdf32 145 Gene3D G3DSA:2.60.120.630 1 141 9.0E-49 T 31-10-2018 IPR023131 Mth639-like domain superfamily AF_1068 ea3d21d6d6b1d9e00e7ca111641bdf32 145 Pfam PF04027 Domain of unknown function (DUF371) 4 135 3.9E-48 T 31-10-2018 IPR007171 Protein of unknown function DUF371 AF_0888 d95dc25ef53b773aa1a64dffe83189e7 332 Pfam PF02653 Branched-chain amino acid transport system / permease component 47 322 8.2E-40 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AF_0624 6f8844606bd6fc6dd6031a0adfb31d77 185 Pfam PF01944 Stage II sporulation protein M 16 179 5.8E-32 T 31-10-2018 IPR002798 Stage II sporulation protein M-like AF_0685 e316bb5458a4ac9a5ab681631396c859 308 Pfam PF00378 Enoyl-CoA hydratase/isomerase 36 288 1.4E-52 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AF_0685 e316bb5458a4ac9a5ab681631396c859 308 Gene3D G3DSA:1.10.12.10 235 288 1.1E-10 T 31-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AF_0685 e316bb5458a4ac9a5ab681631396c859 308 SUPERFAMILY SSF52096 15 288 9.67E-81 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AF_0685 e316bb5458a4ac9a5ab681631396c859 308 Gene3D G3DSA:3.90.226.10 22 230 8.9E-69 T 31-10-2018 AF_0685 e316bb5458a4ac9a5ab681631396c859 308 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 130 150 - T 31-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 AF_0804 3abc851d27061d71f1799b94f8313ea3 64 Pfam PF10049 Protein of unknown function (DUF2283) 2 45 6.3E-10 T 31-10-2018 IPR019270 Protein of unknown function DUF2283 AF_1384 c6b584fcccd671adc330dac15e5a3897 122 Pfam PF00072 Response regulator receiver domain 7 114 8.6E-26 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_1384 c6b584fcccd671adc330dac15e5a3897 122 SMART SM00448 5 114 1.6E-28 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_1384 c6b584fcccd671adc330dac15e5a3897 122 Gene3D G3DSA:3.40.50.2300 1 122 1.7E-35 T 31-10-2018 AF_1384 c6b584fcccd671adc330dac15e5a3897 122 SUPERFAMILY SSF52172 3 118 3.56E-34 T 31-10-2018 IPR011006 CheY-like superfamily AF_0046 11e0c0f8333e78b758982fa6a800257e 473 SUPERFAMILY SSF53335 269 436 1.2E-26 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_0046 11e0c0f8333e78b758982fa6a800257e 473 Gene3D G3DSA:3.40.50.150 243 473 2.2E-80 T 31-10-2018 AF_0046 11e0c0f8333e78b758982fa6a800257e 473 Pfam PF08241 Methyltransferase domain 287 361 4.0E-10 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AF_0589 470ea78834a2b203ef6f8feb6502d219 304 SMART SM01400 21 136 1.4E-25 T 31-10-2018 AF_0589 470ea78834a2b203ef6f8feb6502d219 304 Pfam PF13793 N-terminal domain of ribose phosphate pyrophosphokinase 21 136 2.1E-22 T 31-10-2018 IPR029099 Ribose-phosphate pyrophosphokinase, N-terminal domain KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AF_0589 470ea78834a2b203ef6f8feb6502d219 304 Gene3D G3DSA:3.40.50.2020 26 300 3.7E-71 T 31-10-2018 AF_0589 470ea78834a2b203ef6f8feb6502d219 304 TIGRFAM TIGR01251 ribP_PPkin: ribose-phosphate diphosphokinase 21 303 2.7E-90 T 31-10-2018 IPR005946 Ribose-phosphate pyrophosphokinase GO:0000287|GO:0004749|GO:0009165 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AF_0589 470ea78834a2b203ef6f8feb6502d219 304 SUPERFAMILY SSF53271 18 170 1.24E-28 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like AF_0589 470ea78834a2b203ef6f8feb6502d219 304 Pfam PF00156 Phosphoribosyl transferase domain 163 262 7.8E-10 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AF_0589 470ea78834a2b203ef6f8feb6502d219 304 Hamap MF_00583_A Putative ribose-phosphate pyrophosphokinase [prs]. 22 301 34.316 T 31-10-2018 IPR037514 Ribose-phosphate pyrophosphokinase, archaea GO:0004749 KEGG: 00030+2.7.6.1|KEGG: 00230+2.7.6.1 AF_0589 470ea78834a2b203ef6f8feb6502d219 304 SUPERFAMILY SSF53271 125 287 2.1E-27 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like AF_0589 470ea78834a2b203ef6f8feb6502d219 304 Gene3D G3DSA:3.40.50.2020 161 293 3.7E-71 T 31-10-2018 AF_1552 be251c0e7b9c3b6c570cf149f5466db0 270 SUPERFAMILY SSF103481 41 134 5.89E-9 T 31-10-2018 AF_1552 be251c0e7b9c3b6c570cf149f5466db0 270 SUPERFAMILY SSF103481 178 268 5.23E-14 T 31-10-2018 AF_1552 be251c0e7b9c3b6c570cf149f5466db0 270 TIGRFAM TIGR00950 2A78: carboxylate/amino acid/amine transporter 21 265 3.9E-69 T 31-10-2018 IPR004779 Carboxylate/Amino Acid/Amine Transporter GO:0016021 AF_1552 be251c0e7b9c3b6c570cf149f5466db0 270 Pfam PF00892 EamA-like transporter family 140 267 2.8E-26 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AF_1552 be251c0e7b9c3b6c570cf149f5466db0 270 Pfam PF00892 EamA-like transporter family 10 133 2.1E-14 T 31-10-2018 IPR000620 EamA domain GO:0016020|GO:0016021 AF_2347 d6ac17e296f93cd048605cff008e6ae2 453 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 185 191 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AF_2347 d6ac17e296f93cd048605cff008e6ae2 453 SUPERFAMILY SSF53335 176 347 1.83E-16 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_0154 e1672da181e219b56b2764fa59ab53a7 277 Pfam PF03239 Iron permease FTR1 family 4 265 3.3E-66 T 31-10-2018 IPR004923 Iron permease FTR1/Fip1/EfeU GO:0005381|GO:0016020|GO:0033573|GO:0034755 AF_0154 e1672da181e219b56b2764fa59ab53a7 277 TIGRFAM TIGR00145 TIGR00145: FTR1 family protein 2 274 7.7E-102 T 31-10-2018 IPR005217 Iron permease FTR1-like GO:0005381|GO:0005886|GO:0033573|GO:0034755 AF_0568 e011e447503bf856a288de7ff1e307da 154 Pfam PF00501 AMP-binding enzyme 39 130 2.3E-18 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_0568 e011e447503bf856a288de7ff1e307da 154 SUPERFAMILY SSF56801 32 134 6.28E-23 T 31-10-2018 AF_0568 e011e447503bf856a288de7ff1e307da 154 Gene3D G3DSA:3.40.50.980 22 153 3.4E-24 T 31-10-2018 AF_2103 d38799036c4c5f7204252836604106f4 147 Gene3D G3DSA:1.20.1250.20 1 140 1.5E-16 T 31-10-2018 AF_2103 d38799036c4c5f7204252836604106f4 147 SUPERFAMILY SSF103473 2 123 1.44E-19 T 31-10-2018 IPR036259 MFS transporter superfamily AF_2103 d38799036c4c5f7204252836604106f4 147 Pfam PF07690 Major Facilitator Superfamily 13 117 2.2E-13 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AF_2389-C 8cd1a1ad96a432d21e24dfa738c864ef 65 Gene3D G3DSA:3.30.300.30 1 65 5.8E-8 T 31-10-2018 AF_2389-C 8cd1a1ad96a432d21e24dfa738c864ef 65 Pfam PF13193 AMP-binding enzyme C-terminal domain 1 27 3.3E-7 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AF_2389-C 8cd1a1ad96a432d21e24dfa738c864ef 65 SUPERFAMILY SSF56801 1 55 2.75E-10 T 31-10-2018 AF_1074 3b57552def87a598f5edf4ef1b9ecfb1 64 SUPERFAMILY SSF141694 1 60 1.86E-16 T 31-10-2018 AF_1074 3b57552def87a598f5edf4ef1b9ecfb1 64 Gene3D G3DSA:4.10.1150.10 1 63 7.1E-20 T 31-10-2018 IPR024069 AF2212-like domain superfamily AF_1074 3b57552def87a598f5edf4ef1b9ecfb1 64 Pfam PF01954 Protein of unknown function DUF104 1 57 4.0E-23 T 31-10-2018 IPR008203 Uncharacterised protein family UPF0165 AF_2342 94650aa8f0fc4c3a219a1f2f4a973714 87 Gene3D G3DSA:3.30.2310.20 1 87 1.2E-25 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AF_2342 94650aa8f0fc4c3a219a1f2f4a973714 87 SUPERFAMILY SSF143011 2 85 1.14E-18 T 31-10-2018 IPR035093 Toxin-antitoxin system, RelE/ParE toxin domain superfamily AF_2342 94650aa8f0fc4c3a219a1f2f4a973714 87 Pfam PF05016 ParE toxin of type II toxin-antitoxin system, parDE 4 85 4.7E-9 T 31-10-2018 IPR007712 Toxin-antitoxin system, RelE/ParE toxin family AF_0128 1075e95f9aa575f7b772e3d9db4d009f 202 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 43 1.6E-7 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 AF_2063 47501f65126c364253de7b68463db4dd 137 Pfam PF02996 Prefoldin subunit 17 136 9.1E-30 T 31-10-2018 IPR004127 Prefoldin alpha-like AF_2063 47501f65126c364253de7b68463db4dd 137 TIGRFAM TIGR00293 TIGR00293: prefoldin, alpha subunit 7 136 3.2E-38 T 31-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 AF_2063 47501f65126c364253de7b68463db4dd 137 Hamap MF_00308 Prefoldin subunit alpha [pfdA]. 2 136 15.201 T 31-10-2018 IPR011599 Prefoldin alpha subunit, archaea-type GO:0006457|GO:0016272|GO:0051082 Reactome: R-HSA-389957 AF_2063 47501f65126c364253de7b68463db4dd 137 Gene3D G3DSA:1.10.287.370 6 136 1.1E-32 T 31-10-2018 IPR009053 Prefoldin AF_2063 47501f65126c364253de7b68463db4dd 137 SUPERFAMILY SSF46579 7 136 2.09E-23 T 31-10-2018 AF_0102 f45f58898f2bcbb34d62534d0e1ecf70 188 SUPERFAMILY SSF46785 15 85 4.07E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0102 f45f58898f2bcbb34d62534d0e1ecf70 188 Gene3D G3DSA:1.10.10.10 8 92 4.7E-9 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0102 f45f58898f2bcbb34d62534d0e1ecf70 188 Pfam PF14947 Winged helix-turn-helix 18 80 1.0E-5 T 31-10-2018 IPR038723 ArnR1-like, winged helix-turn-helix domain AF_1692 bd856651bdd57c419288197cef6442b2 209 Gene3D G3DSA:1.10.1670.10 20 201 2.1E-63 T 31-10-2018 IPR023170 Helix-turn-helix, base-excision DNA repair, C-terminal Reactome: R-HSA-110357 AF_1692 bd856651bdd57c419288197cef6442b2 209 SMART SM00478 40 186 2.0E-67 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AF_1692 bd856651bdd57c419288197cef6442b2 209 Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein 36 168 3.7E-28 T 31-10-2018 IPR003265 HhH-GPD domain GO:0006284 Reactome: R-HSA-110357 AF_1692 bd856651bdd57c419288197cef6442b2 209 Pfam PF00633 Helix-hairpin-helix motif 102 130 4.2E-8 T 31-10-2018 IPR000445 Helix-hairpin-helix motif GO:0003677 Reactome: R-HSA-110357 AF_1692 bd856651bdd57c419288197cef6442b2 209 SMART SM00525 187 206 2.6E-4 T 31-10-2018 IPR003651 Endonuclease III-like, iron-sulphur cluster loop motif GO:0051539 Reactome: R-HSA-110357 AF_1692 bd856651bdd57c419288197cef6442b2 209 PIRSF PIRSF001435 7 208 2.3E-47 T 31-10-2018 AF_1692 bd856651bdd57c419288197cef6442b2 209 SUPERFAMILY SSF48150 27 203 8.64E-62 T 31-10-2018 IPR011257 DNA glycosylase GO:0003824|GO:0006281 Reactome: R-HSA-110357 AF_1692 bd856651bdd57c419288197cef6442b2 209 Hamap MF_00942 Endonuclease III [nth]. 4 209 32.445 T 31-10-2018 IPR005759 Endonuclease III GO:0003906|GO:0006284 AF_1692 bd856651bdd57c419288197cef6442b2 209 Gene3D G3DSA:1.10.340.30 23 133 2.1E-63 T 31-10-2018 AF_1692 bd856651bdd57c419288197cef6442b2 209 SMART SM00278 111 130 0.0091 T 31-10-2018 IPR003583 Helix-hairpin-helix DNA-binding motif, class 1 GO:0003677|GO:0006281 AF_2250 0ad90a9ecc66fe7a36bc47aabef0077d 403 TIGRFAM TIGR00857 pyrC_multi: dihydroorotase, multifunctional complex type 10 391 1.3E-138 T 31-10-2018 AF_2250 0ad90a9ecc66fe7a36bc47aabef0077d 403 Pfam PF01979 Amidohydrolase family 39 386 1.2E-16 T 31-10-2018 IPR006680 Amidohydrolase-related GO:0016787 AF_2250 0ad90a9ecc66fe7a36bc47aabef0077d 403 ProSitePatterns PS00483 Dihydroorotase signature 2. 275 286 - T 31-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_2250 0ad90a9ecc66fe7a36bc47aabef0077d 403 ProSitePatterns PS00482 Dihydroorotase signature 1. 46 54 - T 31-10-2018 IPR002195 Dihydroorotase, conserved site GO:0016812 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_2250 0ad90a9ecc66fe7a36bc47aabef0077d 403 SUPERFAMILY SSF51556 44 334 9.19E-65 T 31-10-2018 IPR032466 Metal-dependent hydrolase AF_2250 0ad90a9ecc66fe7a36bc47aabef0077d 403 SUPERFAMILY SSF51338 4 392 5.45E-14 T 31-10-2018 IPR011059 Metal-dependent hydrolase, composite domain superfamily GO:0016810 AF_2250 0ad90a9ecc66fe7a36bc47aabef0077d 403 Hamap MF_00220_A Dihydroorotase [pyrC]. 1 396 64.816 T 31-10-2018 IPR004722 Dihydroorotase GO:0004151|GO:0006221|GO:0046872 KEGG: 00240+3.5.2.3|MetaCyc: PWY-5686|MetaCyc: PWY-7790|MetaCyc: PWY-7791 AF_2250 0ad90a9ecc66fe7a36bc47aabef0077d 403 Gene3D G3DSA:3.20.20.140 34 402 8.7E-88 T 31-10-2018 AF_0460 63f55e8e409bb985c9de4a3a2a28a50b 134 ProDom PD016056 UPF0216 PYRAB16100 PH0358 MTH949 MK1676 AF0460 PF0452 MJ1224 3 133 7.0E-72 T 31-10-2018 IPR002746 Uncharacterised protein family UPF0216 AF_0460 63f55e8e409bb985c9de4a3a2a28a50b 134 PIRSF PIRSF005264 1 134 8.7E-55 T 31-10-2018 IPR002746 Uncharacterised protein family UPF0216 AF_0460 63f55e8e409bb985c9de4a3a2a28a50b 134 Hamap MF_00585 UPF0216 protein . 2 132 25.675 T 31-10-2018 IPR002746 Uncharacterised protein family UPF0216 AF_0460 63f55e8e409bb985c9de4a3a2a28a50b 134 Pfam PF01886 Protein of unknown function DUF61 3 129 3.3E-40 T 31-10-2018 IPR002746 Uncharacterised protein family UPF0216 AF_0122 17feec50ef69aaec623b992f6f4e52c6 210 Pfam PF01629 Domain of unknown function DUF22 58 163 3.7E-42 T 31-10-2018 IPR002572 Domain of unknown function DUF22 AF_1980 5d562719418b7ea56a5d40cf6a958269 218 Pfam PF01578 Cytochrome C assembly protein 29 164 3.1E-33 T 31-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 AF_1980 5d562719418b7ea56a5d40cf6a958269 218 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 106 126 3.9E-16 T 31-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AF_1980 5d562719418b7ea56a5d40cf6a958269 218 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 30 47 3.9E-16 T 31-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AF_1980 5d562719418b7ea56a5d40cf6a958269 218 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 47 67 3.9E-16 T 31-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AF_1980 5d562719418b7ea56a5d40cf6a958269 218 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 85 105 3.9E-16 T 31-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AF_1980 5d562719418b7ea56a5d40cf6a958269 218 PRINTS PR01386 Cytochrome c-type biogenesis protein CcmC signature 183 207 3.9E-16 T 31-10-2018 IPR003557 Cytochrome c-type biogenesis protein CcmC GO:0015232|GO:0015886|GO:0016020|GO:0017004 AF_1601 22ff6239be7a7c5e3cf194e84f093058 199 SUPERFAMILY SSF51366 1 195 5.34E-40 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AF_1601 22ff6239be7a7c5e3cf194e84f093058 199 Pfam PF00697 N-(5'phosphoribosyl)anthranilate (PRA) isomerase 3 192 9.1E-34 T 31-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 AF_1601 22ff6239be7a7c5e3cf194e84f093058 199 Gene3D G3DSA:3.20.20.70 1 198 3.1E-58 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1601 22ff6239be7a7c5e3cf194e84f093058 199 Hamap MF_00135 N-(5'-phosphoribosyl)anthranilate isomerase [trpF]. 1 197 31.396 T 31-10-2018 IPR001240 N-(5'phosphoribosyl) anthranilate isomerase (PRAI) GO:0004640|GO:0006568 KEGG: 00400+5.3.1.24 AF_1527 19ab862585ed7a694fbcc766995d454b 438 Pfam PF01629 Domain of unknown function DUF22 288 391 5.4E-37 T 31-10-2018 IPR002572 Domain of unknown function DUF22 AF_1527 19ab862585ed7a694fbcc766995d454b 438 Pfam PF01629 Domain of unknown function DUF22 3 110 3.1E-38 T 31-10-2018 IPR002572 Domain of unknown function DUF22 AF_1527 19ab862585ed7a694fbcc766995d454b 438 Pfam PF01629 Domain of unknown function DUF22 150 255 5.5E-42 T 31-10-2018 IPR002572 Domain of unknown function DUF22 AF_0707 d52221297c0efab150b48a159e71e919 207 SUPERFAMILY SSF64005 36 201 1.27E-29 T 31-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 AF_0707 d52221297c0efab150b48a159e71e919 207 Gene3D G3DSA:3.40.1180.10 87 207 8.7E-25 T 31-10-2018 IPR036424 Decaprenyl diphosphate synthase-like superfamily GO:0016765 Reactome: R-HSA-446199 AF_0707 d52221297c0efab150b48a159e71e919 207 Pfam PF01255 Putative undecaprenyl diphosphate synthase 108 206 6.9E-18 T 31-10-2018 IPR001441 Decaprenyl diphosphate synthase-like GO:0016765 Reactome: R-HSA-446199 AF_2150 c0c6a3c2ef4f96fd2ade02f4e57bcb15 156 Gene3D G3DSA:3.30.70.640 1 156 3.5E-62 T 31-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AF_2150 c0c6a3c2ef4f96fd2ade02f4e57bcb15 156 SUPERFAMILY SSF55040 9 154 9.42E-50 T 31-10-2018 IPR036522 Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AF_2150 c0c6a3c2ef4f96fd2ade02f4e57bcb15 156 TIGRFAM TIGR00581 moaC: molybdenum cofactor biosynthesis protein C 5 134 4.0E-53 T 31-10-2018 IPR023045 Molybdenum cofactor biosynthesis C GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AF_2150 c0c6a3c2ef4f96fd2ade02f4e57bcb15 156 Pfam PF01967 MoaC family 13 153 8.7E-51 T 31-10-2018 IPR002820 Molybdopterin cofactor biosynthesis C (MoaC) domain GO:0006777 KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823|Reactome: R-HSA-947581 AF_2150 c0c6a3c2ef4f96fd2ade02f4e57bcb15 156 Hamap MF_01224_A Cyclic pyranopterin monophosphate synthase [moaC]. 8 153 39.055 T 31-10-2018 IPR023047 Probable cyclic pyranopterin monophosphate synthase accessory protein, archaea KEGG: 00790+4.6.1.17|MetaCyc: PWY-6823 AF_2051 505e8d33039d1eda6e78dcba67eb758d 191 SUPERFAMILY SSF53335 16 189 1.29E-39 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_2051 505e8d33039d1eda6e78dcba67eb758d 191 Gene3D G3DSA:3.40.50.150 13 191 6.8E-61 T 31-10-2018 AF_2051 505e8d33039d1eda6e78dcba67eb758d 191 Hamap MF_01547 Ribosomal RNA large subunit methyltransferase E [rlmE]. 1 189 29.53 T 31-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 AF_2051 505e8d33039d1eda6e78dcba67eb758d 191 PIRSF PIRSF005461 1 191 1.6E-75 T 31-10-2018 IPR015507 Ribosomal RNA large subunit methyltransferase E GO:0001510|GO:0008168 AF_2051 505e8d33039d1eda6e78dcba67eb758d 191 Pfam PF01728 FtsJ-like methyltransferase 17 188 1.6E-57 T 31-10-2018 IPR002877 Ribosomal RNA methyltransferase FtsJ domain GO:0008168|GO:0032259 AF_2298 511998736ddd7a4c500bc3addddd3e02 280 Gene3D G3DSA:3.90.920.10 8 278 1.0E-47 T 31-10-2018 AF_2298 511998736ddd7a4c500bc3addddd3e02 280 SUPERFAMILY SSF56747 10 269 4.14E-38 T 31-10-2018 AF_0571 214214ecdd64a6b15f971fefbc5eff76 97 Gene3D G3DSA:3.30.70.930 1 96 3.8E-26 T 31-10-2018 IPR029756 MTH1187/YkoF-like AF_0571 214214ecdd64a6b15f971fefbc5eff76 97 TIGRFAM TIGR00106 TIGR00106: uncharacterized protein, MTH1187 family 1 96 6.9E-35 T 31-10-2018 IPR002767 Thiamine-binding protein AF_0571 214214ecdd64a6b15f971fefbc5eff76 97 Pfam PF01910 Thiamine-binding protein 3 93 2.5E-26 T 31-10-2018 IPR002767 Thiamine-binding protein AF_0571 214214ecdd64a6b15f971fefbc5eff76 97 SUPERFAMILY SSF89957 1 96 2.75E-25 T 31-10-2018 IPR029756 MTH1187/YkoF-like AF_0826 4bafe3b58e80b8a13696a82cd9589b69 134 Pfam PF00582 Universal stress protein family 3 134 5.6E-24 T 31-10-2018 IPR006016 UspA AF_0826 4bafe3b58e80b8a13696a82cd9589b69 134 Gene3D G3DSA:3.40.50.620 1 134 1.8E-35 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_0826 4bafe3b58e80b8a13696a82cd9589b69 134 SUPERFAMILY SSF52402 3 134 2.34E-22 T 31-10-2018 AF_0826 4bafe3b58e80b8a13696a82cd9589b69 134 PRINTS PR01438 Universal stress protein signature 3 21 5.9E-6 T 31-10-2018 IPR006015 Universal stress protein A AF_0826 4bafe3b58e80b8a13696a82cd9589b69 134 PRINTS PR01438 Universal stress protein signature 112 134 5.9E-6 T 31-10-2018 IPR006015 Universal stress protein A AF_0826 4bafe3b58e80b8a13696a82cd9589b69 134 PRINTS PR01438 Universal stress protein signature 94 106 5.9E-6 T 31-10-2018 IPR006015 Universal stress protein A AF_1872 210f3e254583f460fd4a98a51b9e50bf 266 Pfam PF09704 CRISPR-associated protein (Cas_Cas5) 10 194 5.8E-5 T 31-10-2018 IPR021124 CRISPR-associated protein, Cas5 GO:0043571 AF_1872 210f3e254583f460fd4a98a51b9e50bf 266 Gene3D G3DSA:3.30.70.3120 1 265 7.9E-131 T 31-10-2018 AF_1872 210f3e254583f460fd4a98a51b9e50bf 266 TIGRFAM TIGR01874 cas_cas5a: CRISPR-associated protein Cas5, subtype I-A/APERN 21 182 2.9E-10 T 31-10-2018 IPR010153 CRISPR-associated protein, Cas5a type AF_2419 a470138e6dd9cd6ffdea89855cb73d33 114 Gene3D G3DSA:3.40.50.2300 1 114 9.9E-36 T 31-10-2018 AF_2419 a470138e6dd9cd6ffdea89855cb73d33 114 Pfam PF00072 Response regulator receiver domain 4 110 1.4E-26 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_2419 a470138e6dd9cd6ffdea89855cb73d33 114 SUPERFAMILY SSF52172 1 114 4.84E-34 T 31-10-2018 IPR011006 CheY-like superfamily AF_2419 a470138e6dd9cd6ffdea89855cb73d33 114 SMART SM00448 2 110 1.6E-31 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_1707 126a85330ae5461b829be71dd940ecd4 219 Gene3D G3DSA:3.30.2010.10 109 205 2.5E-17 T 31-10-2018 AF_1707 126a85330ae5461b829be71dd940ecd4 219 Pfam PF01863 Protein of unknown function DUF45 11 202 4.1E-46 T 31-10-2018 IPR002725 Protein of unknown function DUF45 AF_0354 375b47f6adffe69c2aacb93903b9084c 238 Pfam PF06745 KaiC 6 222 1.6E-24 T 31-10-2018 IPR014774 KaiC-like domain AF_0354 375b47f6adffe69c2aacb93903b9084c 238 Gene3D G3DSA:3.40.50.300 3 224 2.0E-34 T 31-10-2018 AF_0354 375b47f6adffe69c2aacb93903b9084c 238 SUPERFAMILY SSF52540 6 223 2.38E-25 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1517 908c5f8951a3e2e48affe9caaac084ea 162 Gene3D G3DSA:3.40.630.30 13 162 1.9E-23 T 31-10-2018 AF_1517 908c5f8951a3e2e48affe9caaac084ea 162 SUPERFAMILY SSF55729 24 155 4.05E-23 T 31-10-2018 IPR016181 Acyl-CoA N-acyltransferase AF_1517 908c5f8951a3e2e48affe9caaac084ea 162 Pfam PF00583 Acetyltransferase (GNAT) family 49 146 6.8E-15 T 31-10-2018 IPR000182 GNAT domain AF_1414 e3c7caa2e241cb32d94741d68f929a65 476 Gene3D G3DSA:3.20.20.20 142 300 1.2E-8 T 31-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AF_1414 e3c7caa2e241cb32d94741d68f929a65 476 Pfam PF14251 Domain of unknown function (DUF4346) 416 466 2.6E-9 T 31-10-2018 IPR025595 Domain of unknown function DUF4346 AF_1414 e3c7caa2e241cb32d94741d68f929a65 476 SUPERFAMILY SSF51717 126 342 2.62E-28 T 31-10-2018 IPR011005 Dihydropteroate synthase-like GO:0044237 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AF_1414 e3c7caa2e241cb32d94741d68f929a65 476 TIGRFAM TIGR00284 TIGR00284: dihydropteroate synthase-related protein 1 469 2.8E-92 T 31-10-2018 IPR005236 Dihydropteroate synthase-related protein synthase-related protein AF_1414 e3c7caa2e241cb32d94741d68f929a65 476 Pfam PF00809 Pterin binding enzyme 148 241 1.2E-8 T 31-10-2018 IPR000489 Pterin-binding domain GO:0042558 Reactome: R-HSA-156581|Reactome: R-HSA-1614635|Reactome: R-HSA-196741|Reactome: R-HSA-3359467|Reactome: R-HSA-3359469 AF_1963 6a9365dc7d708d5084ee88102045ae7c 433 ProSitePatterns PS00450 Aconitase family signature 1. 305 321 - T 31-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AF_1963 6a9365dc7d708d5084ee88102045ae7c 433 Gene3D G3DSA:3.30.499.20 19 283 2.1E-98 T 31-10-2018 AF_1963 6a9365dc7d708d5084ee88102045ae7c 433 Pfam PF00330 Aconitase family (aconitate hydratase) 23 424 4.0E-96 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AF_1963 6a9365dc7d708d5084ee88102045ae7c 433 Hamap MF_01027 3-isopropylmalate dehydratase large subunit [leuC]. 18 432 51.846 T 31-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AF_1963 6a9365dc7d708d5084ee88102045ae7c 433 TIGRFAM TIGR02086 IPMI_arch: 3-isopropylmalate dehydratase, large subunit 18 430 6.2E-173 T 31-10-2018 IPR011826 Homoaconitase/3-isopropylmalate dehydratase, large subunit, prokaryotic GO:0003861|GO:0009098|GO:0051539 KEGG: 00290+4.2.1.33 AF_1963 6a9365dc7d708d5084ee88102045ae7c 433 Gene3D G3DSA:3.30.499.10 286 433 7.5E-57 T 31-10-2018 IPR015931 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 KEGG: 00290+4.2.1.33 AF_1963 6a9365dc7d708d5084ee88102045ae7c 433 PRINTS PR00415 Aconitase family signature 127 140 3.3E-14 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AF_1963 6a9365dc7d708d5084ee88102045ae7c 433 PRINTS PR00415 Aconitase family signature 309 320 3.3E-14 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AF_1963 6a9365dc7d708d5084ee88102045ae7c 433 PRINTS PR00415 Aconitase family signature 141 156 3.3E-14 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AF_1963 6a9365dc7d708d5084ee88102045ae7c 433 PRINTS PR00415 Aconitase family signature 365 378 3.3E-14 T 31-10-2018 IPR001030 Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain KEGG: 00290+4.2.1.33 AF_1963 6a9365dc7d708d5084ee88102045ae7c 433 SUPERFAMILY SSF53732 14 432 3.14E-144 T 31-10-2018 IPR036008 Aconitase, iron-sulfur domain KEGG: 00290+4.2.1.33 AF_1963 6a9365dc7d708d5084ee88102045ae7c 433 ProSitePatterns PS01244 Aconitase family signature 2. 365 378 - T 31-10-2018 IPR018136 Aconitase family, 4Fe-4S cluster binding site KEGG: 00290+4.2.1.33 AF_1963 6a9365dc7d708d5084ee88102045ae7c 433 TIGRFAM TIGR01343 hacA_fam: homoaconitate hydratase family protein 19 430 6.0E-178 T 31-10-2018 IPR006251 Homoaconitase/3-isopropylmalate dehydratase, large subunit GO:0008652|GO:0016836|GO:0051539 KEGG: 00290+4.2.1.33 AF_2129 2efa44ea2b7a1017fddd6fa77cc0e79e 379 Pfam PF00155 Aminotransferase class I and II 32 374 2.8E-66 T 31-10-2018 IPR004839 Aminotransferase, class I/classII GO:0009058|GO:0030170 AF_2129 2efa44ea2b7a1017fddd6fa77cc0e79e 379 ProSitePatterns PS00105 Aminotransferases class-I pyridoxal-phosphate attachment site. 230 243 - T 31-10-2018 IPR004838 Aminotransferases, class-I, pyridoxal-phosphate-binding site GO:0003824|GO:0009058|GO:0030170 AF_2129 2efa44ea2b7a1017fddd6fa77cc0e79e 379 Gene3D G3DSA:3.90.1150.10 25 373 7.2E-127 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AF_2129 2efa44ea2b7a1017fddd6fa77cc0e79e 379 Gene3D G3DSA:3.40.640.10 64 280 7.2E-127 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AF_2129 2efa44ea2b7a1017fddd6fa77cc0e79e 379 SUPERFAMILY SSF53383 6 378 6.38E-114 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AF_1901 7613992815e1d938cdadf82493d9193b 221 Pfam PF01956 Integral membrane protein DUF106 36 220 1.2E-53 T 31-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 AF_1901 7613992815e1d938cdadf82493d9193b 221 SMART SM01415 35 221 1.0E-47 T 31-10-2018 IPR002809 Integral membrane protein EMC3/TMCO1-like GO:0016020 AF_0420 34195105f72fc4789a1aba3c412b7aa4 69 Hamap MF_01245 UPF0248 protein . 1 69 19.689 T 31-10-2018 IPR007547 Uncharacterised protein family UPF0248 AF_0420 34195105f72fc4789a1aba3c412b7aa4 69 Pfam PF04457 Protein of unknown function (DUF504) 17 68 1.1E-16 T 31-10-2018 IPR007547 Uncharacterised protein family UPF0248 AF_1687 63c54ff1f729e8175a88793615b65f92 215 Pfam PF02593 Domain of unknown function 8 212 3.6E-66 T 31-10-2018 IPR003745 Protein of unknown function DUF166 AF_1478 488e7f05411195e19aba9453a99ca344 71 Pfam PF02697 Putative antitoxin 4 65 7.0E-21 T 31-10-2018 IPR003847 Putative antitoxin AF_1478 488e7f05411195e19aba9453a99ca344 71 ProDom PD188822 UPF0330 AF1997 ST1125.1 AF1689 AF1478 C1_0043 PYRAB04040 PF1222 MM2475 MA1514 4 65 4.0E-27 T 31-10-2018 IPR003847 Putative antitoxin AF_1478 488e7f05411195e19aba9453a99ca344 71 Hamap MF_00794 Putative antitoxin . 3 71 12.998 T 31-10-2018 IPR003847 Putative antitoxin AF_1784 7b4d300ad2a989196ac461391be719f6 177 TIGRFAM TIGR00537 hemK_rel_arch: putative methylase 2 175 9.3E-82 T 31-10-2018 IPR004557 Eukaryotic/archaeal PrmC-related GO:0008276 Reactome: R-HSA-156581|Reactome: R-HSA-72764 AF_1784 7b4d300ad2a989196ac461391be719f6 177 SUPERFAMILY SSF53335 5 166 3.16E-20 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_1784 7b4d300ad2a989196ac461391be719f6 177 ProSitePatterns PS00092 N-6 Adenine-specific DNA methylases signature. 83 89 - T 31-10-2018 IPR002052 DNA methylase, N-6 adenine-specific, conserved site GO:0003676|GO:0008168|GO:0032259 AF_1784 7b4d300ad2a989196ac461391be719f6 177 Gene3D G3DSA:3.40.50.150 1 177 1.3E-32 T 31-10-2018 AF_2297 511b943662f97ac8ea18ece277641dfb 535 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 18 524 1.0E-67 T 31-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 AF_1790 748dc0efd248820b7c17bed7ccbdb241 488 Gene3D G3DSA:2.40.50.140 121 209 1.3E-5 T 31-10-2018 AF_1790 748dc0efd248820b7c17bed7ccbdb241 488 SUPERFAMILY SSF56300 224 458 7.19E-22 T 31-10-2018 AF_1790 748dc0efd248820b7c17bed7ccbdb241 488 PIRSF PIRSF000803 2 488 6.7E-193 T 31-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AF_1790 748dc0efd248820b7c17bed7ccbdb241 488 Pfam PF00149 Calcineurin-like phosphoesterase 228 436 1.2E-15 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AF_1790 748dc0efd248820b7c17bed7ccbdb241 488 Hamap MF_00325 DNA polymerase II small subunit [polB]. 10 484 32.714 T 31-10-2018 IPR011149 DNA polymerase II small subunit, archaeal GO:0003676|GO:0003887|GO:0006260|GO:0008408 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AF_1790 748dc0efd248820b7c17bed7ccbdb241 488 Gene3D G3DSA:3.60.21.50 217 455 4.0E-26 T 31-10-2018 AF_1647 387523f3d6bdc24078a2bec33b494fe2 258 Gene3D G3DSA:3.60.110.10 1 258 1.1E-40 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AF_1647 387523f3d6bdc24078a2bec33b494fe2 258 SUPERFAMILY SSF56317 2 253 3.92E-43 T 31-10-2018 IPR036526 Carbon-nitrogen hydrolase superfamily AF_1647 387523f3d6bdc24078a2bec33b494fe2 258 Pfam PF00795 Carbon-nitrogen hydrolase 4 234 1.2E-38 T 31-10-2018 IPR003010 Carbon-nitrogen hydrolase GO:0006807 AF_0695 8df34808735a439ede651f391ce09892 376 SUPERFAMILY SSF52540 23 280 2.28E-32 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0695 8df34808735a439ede651f391ce09892 376 Hamap MF_01407 ORC1-type DNA replication protein. 16 373 23.359 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea AF_0695 8df34808735a439ede651f391ce09892 376 TIGRFAM TIGR02928 TIGR02928: orc1/cdc6 family replication initiation protein 23 359 1.7E-61 T 31-10-2018 IPR014277 Orc1/Cdc6-type DNA replication protein, archaea AF_0695 8df34808735a439ede651f391ce09892 376 SUPERFAMILY SSF46785 291 369 9.05E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0695 8df34808735a439ede651f391ce09892 376 Gene3D G3DSA:3.40.50.300 39 208 6.9E-63 T 31-10-2018 AF_0695 8df34808735a439ede651f391ce09892 376 Gene3D G3DSA:1.10.8.60 23 280 6.9E-63 T 31-10-2018 AF_0695 8df34808735a439ede651f391ce09892 376 Gene3D G3DSA:1.10.10.10 288 376 2.1E-5 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0695 8df34808735a439ede651f391ce09892 376 SMART SM01074 302 373 5.7E-15 T 31-10-2018 IPR015163 Cdc6, C-terminal Reactome: R-HSA-176187|Reactome: R-HSA-539107|Reactome: R-HSA-68689|Reactome: R-HSA-68827|Reactome: R-HSA-68867|Reactome: R-HSA-68949|Reactome: R-HSA-68962 AF_1443 47fef3fc2fda87ea538cdc61189b464f 248 Pfam PF06745 KaiC 8 244 1.9E-79 T 31-10-2018 IPR014774 KaiC-like domain AF_1443 47fef3fc2fda87ea538cdc61189b464f 248 SUPERFAMILY SSF52540 5 242 2.21E-39 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1443 47fef3fc2fda87ea538cdc61189b464f 248 Gene3D G3DSA:3.40.50.300 3 247 3.2E-63 T 31-10-2018 AF_2056 ebb71b3d53438842969dc7b30ccef503 113 Hamap MF_00236 Sec-independent protein translocase protein TatA [tatA]. 9 73 16.19 T 31-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 AF_2056 ebb71b3d53438842969dc7b30ccef503 113 Pfam PF02416 mttA/Hcf106 family 12 62 2.1E-21 T 31-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 AF_2056 ebb71b3d53438842969dc7b30ccef503 113 TIGRFAM TIGR01411 tatAE: twin arginine-targeting protein translocase, TatA/E family 12 56 1.6E-21 T 31-10-2018 IPR006312 Sec-independent protein translocase protein TatA/E GO:0005886|GO:0008565|GO:0009306|GO:0015031|GO:0016021 AF_1834 a9f02cb076c190834faca75b054d9ed3 189 Gene3D G3DSA:1.20.58.290 124 189 7.0E-31 T 31-10-2018 AF_1834 a9f02cb076c190834faca75b054d9ed3 189 Gene3D G3DSA:2.30.110.10 1 123 1.1E-36 T 31-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AF_1834 a9f02cb076c190834faca75b054d9ed3 189 SUPERFAMILY SSF50475 1 188 2.22E-52 T 31-10-2018 AF_1834 a9f02cb076c190834faca75b054d9ed3 189 Pfam PF04289 Protein of unknown function (DUF447) 13 186 4.1E-48 T 31-10-2018 IPR007386 Protein of unknown function DUF447 AF_1537 4e8c3582996a719cb5390dbd63009611 251 Pfam PF12697 Alpha/beta hydrolase family 27 241 3.9E-17 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_1537 4e8c3582996a719cb5390dbd63009611 251 PRINTS PR00111 Alpha/beta hydrolase fold signature 43 58 3.6E-9 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_1537 4e8c3582996a719cb5390dbd63009611 251 PRINTS PR00111 Alpha/beta hydrolase fold signature 85 98 3.6E-9 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_1537 4e8c3582996a719cb5390dbd63009611 251 PRINTS PR00111 Alpha/beta hydrolase fold signature 99 112 3.6E-9 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_1537 4e8c3582996a719cb5390dbd63009611 251 PRINTS PR00111 Alpha/beta hydrolase fold signature 192 206 3.6E-9 T 31-10-2018 IPR000073 Alpha/beta hydrolase fold-1 AF_1537 4e8c3582996a719cb5390dbd63009611 251 Gene3D G3DSA:3.40.50.1820 1 249 1.2E-79 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_1537 4e8c3582996a719cb5390dbd63009611 251 SUPERFAMILY SSF53474 21 247 1.65E-42 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_1134 258eeb5b83e21e418b154ae25127f091 456 SUPERFAMILY SSF53474 21 424 4.33E-33 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_1134 258eeb5b83e21e418b154ae25127f091 456 Pfam PF12146 Serine aminopeptidase, S33 106 191 2.1E-6 T 31-10-2018 IPR022742 Serine aminopeptidase, S33 AF_2359 9abc76f6094f44091d1d3279cb51d278 75 SMART SM00966 3 50 1.4E-11 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AF_2359 9abc76f6094f44091d1d3279cb51d278 75 Pfam PF04014 Antidote-toxin recognition MazE, bacterial antitoxin 3 49 1.7E-11 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AF_2359 9abc76f6094f44091d1d3279cb51d278 75 SUPERFAMILY SSF89447 2 43 5.93E-10 T 31-10-2018 IPR037914 SpoVT-AbrB domain superfamily AF_2359 9abc76f6094f44091d1d3279cb51d278 75 TIGRFAM TIGR01439 lp_hng_hel_AbrB: transcriptional regulator, AbrB family 2 37 1.3E-14 T 31-10-2018 IPR007159 SpoVT-AbrB domain GO:0003677 AF_2359 9abc76f6094f44091d1d3279cb51d278 75 Gene3D G3DSA:2.10.260.10 2 44 2.1E-14 T 31-10-2018 AF_1442 80fb90659791618b40e96437d29fc897 370 Hamap MF_02067 Fructose-1,6-bisphosphate aldolase/phosphatase [fbp]. 2 368 59.667 T 31-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 AF_1442 80fb90659791618b40e96437d29fc897 370 PIRSF PIRSF015647 2 370 8.9E-191 T 31-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 AF_1442 80fb90659791618b40e96437d29fc897 370 SUPERFAMILY SSF111249 3 368 1.44E-176 T 31-10-2018 IPR036076 Fructose-1,6-bisphosphatase, class V superfamily KEGG: 00010+3.1.3.11+4.1.2.13|KEGG: 00030+3.1.3.11+4.1.2.13|KEGG: 00051+3.1.3.11+4.1.2.13|KEGG: 00680+3.1.3.11+4.1.2.13|KEGG: 00710+3.1.3.11+4.1.2.13|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 AF_1442 80fb90659791618b40e96437d29fc897 370 ProDom PD014260 DIHYDROOROTATE DEHYDROGENASE THERMOPHILE-SPECIFIC TA1428 ST0318 BLL2851 16-BISPHOSPHATASE APE1109 PF0613 MJ0299 1 367 0.0 T 31-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 AF_1442 80fb90659791618b40e96437d29fc897 370 Pfam PF01950 Fructose-1,6-bisphosphatase 3 368 1.8E-183 T 31-10-2018 IPR002803 Fructose-1,6-bisphosphatase, class V KEGG: 00010+4.1.2.13+3.1.3.11|KEGG: 00030+4.1.2.13+3.1.3.11|KEGG: 00051+4.1.2.13+3.1.3.11|KEGG: 00680+4.1.2.13+3.1.3.11|KEGG: 00710+4.1.2.13+3.1.3.11|MetaCyc: PWY-1042|MetaCyc: PWY-1861|MetaCyc: PWY-5484|MetaCyc: PWY-6142|MetaCyc: PWY-7385 AF_1178 0b88267e45ed534a8dbbba862412362a 106 SUPERFAMILY SSF101386 1 102 4.25E-31 T 31-10-2018 AF_1178 0b88267e45ed534a8dbbba862412362a 106 PIRSF PIRSF029826 1 106 7.9E-39 T 31-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 AF_1178 0b88267e45ed534a8dbbba862412362a 106 Gene3D G3DSA:1.10.287.1080 1 106 5.8E-39 T 31-10-2018 AF_1178 0b88267e45ed534a8dbbba862412362a 106 Pfam PF12643 MazG-like family 28 104 7.3E-17 T 31-10-2018 IPR025984 dCTP pyrophosphatase 1 GO:0009143|GO:0047429 KEGG: 00240+3.6.1.12|Reactome: R-HSA-499943 AF_0754 16fbd86fdc3b879a9ba6897e0f6522ce 379 Gene3D G3DSA:1.10.10.10 131 236 3.3E-6 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0754 16fbd86fdc3b879a9ba6897e0f6522ce 379 SUPERFAMILY SSF46785 130 236 1.32E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1835 2f7052c3faefdfdf22a0d83b032cdb5c 277 Pfam PF01874 ATP:dephospho-CoA triphosphoribosyl transferase 12 270 1.1E-57 T 31-10-2018 IPR002736 Triphosphoribosyl-dephospho-CoA protein GO:0005524|GO:0016310|GO:0046917 MetaCyc: PWY-5796 AF_1835 2f7052c3faefdfdf22a0d83b032cdb5c 277 Gene3D G3DSA:1.10.4200.10 28 276 2.1E-94 T 31-10-2018 AF_0819 fb6c4458c3644c535f93793c14b21c17 271 SUPERFAMILY SSF51366 1 270 3.3E-81 T 31-10-2018 IPR011060 Ribulose-phosphate binding barrel GO:0003824 AF_0819 fb6c4458c3644c535f93793c14b21c17 271 Hamap MF_01013 Imidazole glycerol phosphate synthase subunit HisF [hisF]. 1 270 50.728 T 31-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 AF_0819 fb6c4458c3644c535f93793c14b21c17 271 TIGRFAM TIGR00735 hisF: imidazoleglycerol phosphate synthase, cyclase subunit 1 270 7.0E-129 T 31-10-2018 IPR004651 Histidine biosynthesis, HisF GO:0000105|GO:0000107|GO:0005737 AF_0819 fb6c4458c3644c535f93793c14b21c17 271 Gene3D G3DSA:3.20.20.70 1 271 7.0E-107 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0819 fb6c4458c3644c535f93793c14b21c17 271 Pfam PF00977 Histidine biosynthesis protein 5 253 1.9E-91 T 31-10-2018 IPR006062 Histidine biosynthesis GO:0000105 AF_0386 3f3ab231f61ff56d32c4f1126c49bff0 195 SUPERFAMILY SSF53271 44 185 3.15E-27 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like AF_0386 3f3ab231f61ff56d32c4f1126c49bff0 195 Hamap MF_01214 PyrE-like protein. 1 195 35.035 T 31-10-2018 IPR022854 PyrE-like AF_0386 3f3ab231f61ff56d32c4f1126c49bff0 195 Pfam PF00156 Phosphoribosyl transferase domain 60 180 9.5E-20 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AF_0386 3f3ab231f61ff56d32c4f1126c49bff0 195 Gene3D G3DSA:3.40.50.2020 42 195 9.5E-33 T 31-10-2018 AF_0337 d409d20b8a798976ce3260352f4b8cfd 72 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 7 69 7.9E-21 T 31-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain AF_0337 d409d20b8a798976ce3260352f4b8cfd 72 Gene3D G3DSA:1.10.20.10 3 70 9.2E-22 T 31-10-2018 IPR009072 Histone-fold GO:0046982 AF_0337 d409d20b8a798976ce3260352f4b8cfd 72 SUPERFAMILY SSF47113 7 72 8.1E-21 T 31-10-2018 IPR009072 Histone-fold GO:0046982 AF_1038 6390aa3f0b73601de972049528aaaa8e 157 SUPERFAMILY SSF64438 4 155 1.01E-48 T 31-10-2018 IPR011324 Cytotoxic necrotizing factor-like, catalytic AF_1038 6390aa3f0b73601de972049528aaaa8e 157 Gene3D G3DSA:3.30.1330.200 3 155 2.1E-52 T 31-10-2018 IPR038592 CheD-like superfamily AF_1038 6390aa3f0b73601de972049528aaaa8e 157 Hamap MF_01440 Chemoreceptor glutamine deamidase CheD [cheD]. 1 153 28.946 T 31-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 AF_1038 6390aa3f0b73601de972049528aaaa8e 157 Pfam PF03975 CheD chemotactic sensory transduction 47 148 9.9E-35 T 31-10-2018 IPR005659 Chemoreceptor glutamine deamidase CheD GO:0006935|GO:0050568 AF_0147 64de4979098bcb3a0a419aebbd07acae 174 Pfam PF04893 Yip1 domain 20 161 7.4E-21 T 31-10-2018 IPR006977 Yip1 domain GO:0016020 AF_0110 ad13dc57c485594c31d1e502a4e29ea7 534 SUPERFAMILY SSF55681 35 348 5.69E-38 T 31-10-2018 AF_0110 ad13dc57c485594c31d1e502a4e29ea7 534 Gene3D G3DSA:3.30.930.10 42 354 1.5E-74 T 31-10-2018 AF_0110 ad13dc57c485594c31d1e502a4e29ea7 534 Gene3D G3DSA:3.30.160.480 1 27 3.3E-20 T 31-10-2018 AF_0110 ad13dc57c485594c31d1e502a4e29ea7 534 Hamap MF_01674 O-phosphoserine--tRNA(Cys) ligase [sepS]. 1 534 292.212 T 31-10-2018 IPR005246 O-phosphoseryl-tRNA(Cys) ligase GO:0004812|GO:0005524|GO:0043039 KEGG: 00970+6.1.1.27|MetaCyc: PWY-6308 AF_0110 ad13dc57c485594c31d1e502a4e29ea7 534 Pfam PF01409 tRNA synthetases class II core domain (F) 107 351 6.4E-58 T 31-10-2018 IPR002319 Phenylalanyl-tRNA synthetase GO:0000049|GO:0004812|GO:0005524|GO:0005737|GO:0043039 KEGG: 00970+6.1.1.20 AF_0110 ad13dc57c485594c31d1e502a4e29ea7 534 TIGRFAM TIGR00470 sepS: O-phosphoserine--tRNA ligase 1 534 2.2E-302 T 31-10-2018 IPR005246 O-phosphoseryl-tRNA(Cys) ligase GO:0004812|GO:0005524|GO:0043039 KEGG: 00970+6.1.1.27|MetaCyc: PWY-6308 AF_1898 d35f9a4f5528198914e1dd23de03505e 117 Pfam PF00072 Response regulator receiver domain 4 110 1.2E-27 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_1898 d35f9a4f5528198914e1dd23de03505e 117 SUPERFAMILY SSF52172 1 115 1.25E-35 T 31-10-2018 IPR011006 CheY-like superfamily AF_1898 d35f9a4f5528198914e1dd23de03505e 117 Gene3D G3DSA:3.40.50.2300 1 117 7.9E-38 T 31-10-2018 AF_1898 d35f9a4f5528198914e1dd23de03505e 117 SMART SM00448 2 110 1.9E-32 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_0015 7904c0d04d73db307a063704364e3424 491 ProSitePatterns PS00456 Sodium:solute symporter family signature 1. 153 178 - T 31-10-2018 IPR018212 Sodium/solute symporter, conserved site AF_0015 7904c0d04d73db307a063704364e3424 491 Gene3D G3DSA:1.20.1730.10 22 490 8.4E-65 T 31-10-2018 IPR038377 Sodium/glucose symporter superfamily AF_0015 7904c0d04d73db307a063704364e3424 491 Pfam PF00474 Sodium:solute symporter family 34 425 2.9E-51 T 31-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AF_2313 682a4204370f0c65f26931d90e9a35ad 151 SUPERFAMILY SSF54637 2 148 3.26E-50 T 31-10-2018 IPR029069 HotDog domain superfamily AF_2313 682a4204370f0c65f26931d90e9a35ad 151 Pfam PF01575 MaoC like domain 11 122 1.9E-39 T 31-10-2018 IPR002539 MaoC-like dehydratase domain AF_2313 682a4204370f0c65f26931d90e9a35ad 151 Gene3D G3DSA:3.10.129.10 1 151 2.3E-55 T 31-10-2018 AF_0289 be9e0045e184c84ad01398942fc48d4a 252 Pfam PF01061 ABC-2 type transporter 11 212 3.2E-22 T 31-10-2018 IPR013525 ABC-2 type transporter GO:0016020 Reactome: R-HSA-1369062 AF_0080 c255039b8658e676119ad245ea9f9ee0 375 Hamap MF_01107 Acetylornithine/succinyldiaminopimelate aminotransferase [argD]. 10 374 68.164 T 31-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 AF_0080 c255039b8658e676119ad245ea9f9ee0 375 PIRSF PIRSF000521 5 121 1.5E-11 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AF_0080 c255039b8658e676119ad245ea9f9ee0 375 PIRSF PIRSF000521 114 375 1.3E-36 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AF_0080 c255039b8658e676119ad245ea9f9ee0 375 SUPERFAMILY SSF53383 3 373 5.98E-129 T 31-10-2018 IPR015424 Pyridoxal phosphate-dependent transferase AF_0080 c255039b8658e676119ad245ea9f9ee0 375 ProSitePatterns PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. 211 248 - T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AF_0080 c255039b8658e676119ad245ea9f9ee0 375 Pfam PF00202 Aminotransferase class-III 18 373 6.9E-117 T 31-10-2018 IPR005814 Aminotransferase class-III GO:0008483|GO:0030170 AF_0080 c255039b8658e676119ad245ea9f9ee0 375 Gene3D G3DSA:3.90.1150.10 21 371 1.2E-143 T 31-10-2018 IPR015422 Pyridoxal phosphate-dependent transferase domain 1 GO:0003824 AF_0080 c255039b8658e676119ad245ea9f9ee0 375 Gene3D G3DSA:3.40.640.10 54 293 1.2E-143 T 31-10-2018 IPR015421 Pyridoxal phosphate-dependent transferase, major domain GO:0003824 AF_0080 c255039b8658e676119ad245ea9f9ee0 375 TIGRFAM TIGR00707 argD: transaminase, acetylornithine/succinylornithine family 11 373 9.3E-167 T 31-10-2018 IPR004636 Acetylornithine/Succinylornithine transaminase family GO:0006525|GO:0008483 AF_0936 be1ac732f5beaebf6ad60efa064bed51 240 Pfam PF06847 Archaeal Peptidase A24 C-terminus Type II 148 229 3.3E-19 T 31-10-2018 IPR009655 Preflagellin peptidase, C-terminal AF_0936 be1ac732f5beaebf6ad60efa064bed51 240 Gene3D G3DSA:3.30.1360.160 126 211 9.9E-24 T 31-10-2018 AF_0936 be1ac732f5beaebf6ad60efa064bed51 240 Pfam PF01478 Type IV leader peptidase family 8 127 3.0E-13 T 31-10-2018 IPR000045 Prepilin type IV endopeptidase, peptidase domain GO:0004190|GO:0016020 AF_0936 be1ac732f5beaebf6ad60efa064bed51 240 Gene3D G3DSA:1.20.120.1220 26 230 9.9E-24 T 31-10-2018 AF_1155 34f4a5c8bead32e5cb31b5ce8ca4f7b3 222 Gene3D G3DSA:3.60.21.10 19 157 7.2E-10 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like AF_1155 34f4a5c8bead32e5cb31b5ce8ca4f7b3 222 PIRSF PIRSF000887 1 222 1.2E-68 T 31-10-2018 IPR024173 Phosphoesterase, MJ0037 AF_1155 34f4a5c8bead32e5cb31b5ce8ca4f7b3 222 Pfam PF12850 Calcineurin-like phosphoesterase superfamily domain 18 148 2.1E-8 T 31-10-2018 IPR024654 Calcineurin-like phosphoesterase domain, lpxH type Reactome: R-HSA-3238698 AF_1155 34f4a5c8bead32e5cb31b5ce8ca4f7b3 222 TIGRFAM TIGR00024 SbcD_rel_arch: putative phosphoesterase 1 221 7.4E-97 T 31-10-2018 IPR004376 Conserved hypothetical protein CHP00024, phosphoesterase-like AF_1155 34f4a5c8bead32e5cb31b5ce8ca4f7b3 222 SUPERFAMILY SSF56300 18 160 3.32E-17 T 31-10-2018 AF_0940 77ddefc4a6bafc1137d6dba8021d704f 360 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 331 354 2.5E-45 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 AF_0940 77ddefc4a6bafc1137d6dba8021d704f 360 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 104 121 2.5E-45 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 AF_0940 77ddefc4a6bafc1137d6dba8021d704f 360 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 163 181 2.5E-45 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 AF_0940 77ddefc4a6bafc1137d6dba8021d704f 360 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 219 239 2.5E-45 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 AF_0940 77ddefc4a6bafc1137d6dba8021d704f 360 PRINTS PR01552 DNA topoisomerase VI subunit A (TOP6A) signature 34 54 2.5E-45 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 AF_0940 77ddefc4a6bafc1137d6dba8021d704f 360 Hamap MF_00132 Type 2 DNA topoisomerase 6 subunit A [top6A]. 2 360 41.359 T 31-10-2018 IPR004085 DNA topoisomerase VI, subunit A GO:0003677|GO:0003918|GO:0005694|GO:0006265 AF_0940 77ddefc4a6bafc1137d6dba8021d704f 360 SUPERFAMILY SSF56726 67 358 3.01E-87 T 31-10-2018 IPR036078 Spo11/DNA topoisomerase VI subunit A superfamily GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 AF_0940 77ddefc4a6bafc1137d6dba8021d704f 360 Gene3D G3DSA:3.40.1360.10 137 360 1.2E-75 T 31-10-2018 AF_0940 77ddefc4a6bafc1137d6dba8021d704f 360 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 110 127 1.1E-13 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 AF_0940 77ddefc4a6bafc1137d6dba8021d704f 360 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 213 234 1.1E-13 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 AF_0940 77ddefc4a6bafc1137d6dba8021d704f 360 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 189 206 1.1E-13 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 AF_0940 77ddefc4a6bafc1137d6dba8021d704f 360 PRINTS PR01550 DNA topoisomerase VI subunit A family signature 245 261 1.1E-13 T 31-10-2018 IPR002815 Spo11/DNA topoisomerase VI subunit A GO:0000737|GO:0003677|GO:0005694 Reactome: R-HSA-912446 AF_0940 77ddefc4a6bafc1137d6dba8021d704f 360 Pfam PF04406 Type IIB DNA topoisomerase 69 133 2.2E-16 T 31-10-2018 IPR013049 Spo11/DNA topoisomerase VI, subunit A, N-terminal GO:0003677|GO:0003824|GO:0005524|GO:0005694|GO:0006259 Reactome: R-HSA-912446 AF_0940 77ddefc4a6bafc1137d6dba8021d704f 360 Gene3D G3DSA:1.10.10.10 1 136 1.5E-47 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0016 215c6c27f819bcfbe66d989e8c26ddab 215 Pfam PF09719 Putative redox-active protein (C_GCAxxG_C_C) 39 106 2.3E-6 T 31-10-2018 IPR010181 CGCAxxGCC motif AF_0016 215c6c27f819bcfbe66d989e8c26ddab 215 SUPERFAMILY SSF48695 5 180 3.64E-51 T 31-10-2018 IPR036280 Multiheme cytochrome superfamily AF_0385 604ff0d8a6da63296b08b1907b7d4a8d 166 Gene3D G3DSA:3.40.50.1010 1 125 1.4E-29 T 31-10-2018 AF_0385 604ff0d8a6da63296b08b1907b7d4a8d 166 Pfam PF17146 PIN domain of ribonuclease 8 86 1.3E-17 T 31-10-2018 IPR033411 Ribonuclease, PIN domain Reactome: R-HSA-6791226 AF_0385 604ff0d8a6da63296b08b1907b7d4a8d 166 Hamap MF_00265 tRNA(fMet)-specific endonuclease VapC [vapC]. 7 151 9.654 T 31-10-2018 IPR022907 VapC family GO:0004540 AF_2201 e2432a6f0459eeed58f2ad5565091d2d 184 Pfam PF09918 Uncharacterized protein containing a ferredoxin domain (DUF2148) 115 180 5.1E-32 T 31-10-2018 IPR019224 Protein of unknown function DUF2148 AF_2201 e2432a6f0459eeed58f2ad5565091d2d 184 Gene3D G3DSA:3.40.109.10 6 168 5.0E-6 T 31-10-2018 IPR000415 Nitroreductase-like GO:0016491 Reactome: R-HSA-209968 AF_2318 7d8551b458bc106bb4516ae16f38d451 145 Gene3D G3DSA:3.30.1440.10 1 145 3.8E-57 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_2318 7d8551b458bc106bb4516ae16f38d451 145 Pfam PF01877 RNA binding 7 123 2.1E-39 T 31-10-2018 IPR002739 Uncharacterised protein family UPF0201 AF_2318 7d8551b458bc106bb4516ae16f38d451 145 SUPERFAMILY SSF55282 5 141 3.24E-41 T 31-10-2018 IPR022803 Ribosomal protein L5 domain superfamily Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0609 94f3820788badb9e01f224ed69f94932 36 SUPERFAMILY SSF46689 2 26 6.63E-5 T 31-10-2018 IPR009057 Homeobox-like domain superfamily GO:0003677 AF_0609 94f3820788badb9e01f224ed69f94932 36 Pfam PF04255 Protein of unknown function (DUF433) 5 25 3.9E-7 T 31-10-2018 IPR007367 Protein of unknown function DUF433 AF_0551 a9ed39ab57899b2e8fd84fa42aa036e7 404 Gene3D G3DSA:3.40.50.1100 106 203 2.3E-102 T 31-10-2018 AF_0551 a9ed39ab57899b2e8fd84fa42aa036e7 404 SUPERFAMILY SSF53686 3 394 8.91E-88 T 31-10-2018 IPR036052 Tryptophan synthase beta subunit-like PLP-dependent enzyme AF_0551 a9ed39ab57899b2e8fd84fa42aa036e7 404 Pfam PF00291 Pyridoxal-phosphate dependent enzyme 71 373 9.7E-65 T 31-10-2018 IPR001926 Pyridoxal-phosphate dependent enzyme AF_0551 a9ed39ab57899b2e8fd84fa42aa036e7 404 Gene3D G3DSA:3.40.50.1100 57 378 2.3E-102 T 31-10-2018 AF_0551 a9ed39ab57899b2e8fd84fa42aa036e7 404 TIGRFAM TIGR00260 thrC: threonine synthase 55 380 1.6E-107 T 31-10-2018 IPR004450 Threonine synthase-like AF_1306 9f869b41806a912ec50192e70a9b817c 275 Pfam PF04015 Domain of unknown function (DUF362) 32 219 1.1E-34 T 31-10-2018 IPR007160 Domain of unknown function DUF362 AF_1121 a8c38a1caf31c32f54d792023802e05c 155 SMART SM00344 2 111 1.6E-31 T 31-10-2018 IPR019888 Transcription regulator AsnC-type GO:0003700|GO:0005622|GO:0006355|GO:0043565 AF_1121 a8c38a1caf31c32f54d792023802e05c 155 SUPERFAMILY SSF46785 3 52 5.06E-10 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1121 a8c38a1caf31c32f54d792023802e05c 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 27 46 6.5E-5 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_1121 a8c38a1caf31c32f54d792023802e05c 155 PRINTS PR00033 AsnC bacterial regulatory protein HTH signature 16 27 6.5E-5 T 31-10-2018 IPR000485 AsnC-type HTH domain GO:0043565 AF_1121 a8c38a1caf31c32f54d792023802e05c 155 Pfam PF12840 Helix-turn-helix domain 6 51 2.5E-7 T 31-10-2018 AF_1121 a8c38a1caf31c32f54d792023802e05c 155 Gene3D G3DSA:1.10.10.10 4 56 4.3E-8 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1121 a8c38a1caf31c32f54d792023802e05c 155 Gene3D G3DSA:3.30.70.920 57 154 3.6E-6 T 31-10-2018 AF_1863 687a4cf3e051dba485f649760f8ac0fa 355 TIGRFAM TIGR02580 cas_RAMP_Cmr4: CRISPR type III-B/RAMP module RAMP protein Cmr4 10 342 1.5E-79 T 31-10-2018 IPR013410 CRISPR-associated RAMP Cmr4 AF_1863 687a4cf3e051dba485f649760f8ac0fa 355 Pfam PF03787 RAMP superfamily 14 342 1.3E-31 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein AF_0668 063f569c1e243c1de4cf909daebd891d 101 Pfam PF02579 Dinitrogenase iron-molybdenum cofactor 13 99 6.3E-25 T 31-10-2018 IPR003731 Dinitrogenase iron-molybdenum cofactor biosynthesis AF_0668 063f569c1e243c1de4cf909daebd891d 101 Gene3D G3DSA:3.30.420.130 1 101 6.9E-28 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily AF_0668 063f569c1e243c1de4cf909daebd891d 101 SUPERFAMILY SSF53146 1 99 4.32E-26 T 31-10-2018 IPR036105 Dinitrogenase iron-molybdenum cofactor biosynthesis superfamily AF_1614 2d0860587885ecea5d59980b5e2faf50 128 SUPERFAMILY SSF81593 9 127 2.39E-22 T 31-10-2018 AF_1614 2d0860587885ecea5d59980b5e2faf50 128 SMART SM00748 10 121 1.2E-40 T 31-10-2018 IPR007842 HEPN domain AF_1614 2d0860587885ecea5d59980b5e2faf50 128 Pfam PF05168 HEPN domain 6 126 2.2E-29 T 31-10-2018 IPR007842 HEPN domain AF_1614 2d0860587885ecea5d59980b5e2faf50 128 Gene3D G3DSA:1.20.120.330 2 128 1.3E-23 T 31-10-2018 AF_2031 11909b134e97d1a133021247e7797f29 286 Gene3D G3DSA:1.10.287.950 2 97 3.2E-5 T 31-10-2018 AF_2031 11909b134e97d1a133021247e7797f29 286 SUPERFAMILY SSF58104 33 207 1.13E-5 T 31-10-2018 AF_0068 71b15b116dea7d678687d7bf74fb59a3 317 Pfam PF01905 CRISPR-associated negative auto-regulator DevR/Csa2 9 278 1.3E-73 T 31-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR AF_0068 71b15b116dea7d678687d7bf74fb59a3 317 TIGRFAM TIGR01875 cas_MJ0381: CRISPR-associated autoregulator DevR family 7 262 1.4E-58 T 31-10-2018 IPR010154 CRISPR-associated protein Cas7/Cst2/DevR AF_1742 a93798334b3405e68f2636b9819c529a 421 PIRSF PIRSF012876 108 421 3.3E-156 T 31-10-2018 IPR014466 Predicted transcriptional regulator, AF1742 type AF_1742 a93798334b3405e68f2636b9819c529a 421 SUPERFAMILY SSF46785 115 169 8.44E-6 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1742 a93798334b3405e68f2636b9819c529a 421 Gene3D G3DSA:3.40.190.10 271 415 2.8E-10 T 31-10-2018 AF_2111 ffbd6106003c77e27c1038b0d3038960 213 TIGRFAM TIGR00427 TIGR00427: membrane protein, MarC family 1 204 2.7E-84 T 31-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 AF_2111 ffbd6106003c77e27c1038b0d3038960 213 Pfam PF01914 MarC family integral membrane protein 8 207 1.9E-70 T 31-10-2018 IPR002771 Multiple antibiotic resistance (MarC)-related GO:0016021 AF_1520 74f3c87baab3e7658c3fe0a0f0b1feb9 488 Pfam PF00258 Flavodoxin 352 481 5.6E-15 T 31-10-2018 IPR008254 Flavodoxin/nitric oxide synthase GO:0010181 AF_1520 74f3c87baab3e7658c3fe0a0f0b1feb9 488 PIRSF PIRSF005243 97 488 1.3E-186 T 31-10-2018 IPR016440 Rubredoxin-oxygen oxidoreductase GO:0009055|GO:0010181|GO:0016491|GO:0046872 AF_1520 74f3c87baab3e7658c3fe0a0f0b1feb9 488 Gene3D G3DSA:3.40.50.360 346 485 8.9E-43 T 31-10-2018 IPR029039 Flavoprotein-like superfamily AF_1520 74f3c87baab3e7658c3fe0a0f0b1feb9 488 SUPERFAMILY SSF56281 109 384 9.48E-48 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_1520 74f3c87baab3e7658c3fe0a0f0b1feb9 488 SMART SM00849 132 324 1.9E-30 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_1520 74f3c87baab3e7658c3fe0a0f0b1feb9 488 Gene3D G3DSA:3.60.15.10 94 343 4.0E-96 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_1520 74f3c87baab3e7658c3fe0a0f0b1feb9 488 SUPERFAMILY SSF52218 348 488 3.52E-39 T 31-10-2018 IPR029039 Flavoprotein-like superfamily AF_1520 74f3c87baab3e7658c3fe0a0f0b1feb9 488 Pfam PF00753 Metallo-beta-lactamase superfamily 132 277 3.1E-8 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_0239 a3bcf028588b53512d258b9a3b7d2d27 194 Gene3D G3DSA:3.40.50.2020 4 179 7.6E-47 T 31-10-2018 AF_0239 a3bcf028588b53512d258b9a3b7d2d27 194 SUPERFAMILY SSF53271 2 158 3.15E-43 T 31-10-2018 IPR029057 Phosphoribosyltransferase-like AF_0239 a3bcf028588b53512d258b9a3b7d2d27 194 Pfam PF00156 Phosphoribosyl transferase domain 10 150 6.8E-25 T 31-10-2018 IPR000836 Phosphoribosyltransferase domain GO:0009116 AF_1277 e2a0d197798d071512e614c68fe52577 213 Pfam PF00117 Glutamine amidotransferase class-I 35 168 6.2E-16 T 31-10-2018 IPR017926 Glutamine amidotransferase AF_1277 e2a0d197798d071512e614c68fe52577 213 SUPERFAMILY SSF52317 19 181 3.11E-40 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_1277 e2a0d197798d071512e614c68fe52577 213 Gene3D G3DSA:3.40.50.880 1 212 6.1E-51 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_1006 56426080836cea1a8d8d0add1d7cf242 285 Pfam PF00005 ABC transporter 20 148 1.6E-28 T 31-10-2018 IPR003439 ABC transporter-like GO:0005524|GO:0016887 AF_1006 56426080836cea1a8d8d0add1d7cf242 285 ProSitePatterns PS00211 ABC transporters family signature. 120 134 - T 31-10-2018 IPR017871 ABC transporter, conserved site GO:0005524|GO:0016887 AF_1006 56426080836cea1a8d8d0add1d7cf242 285 SMART SM00382 28 195 2.1E-14 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_1006 56426080836cea1a8d8d0add1d7cf242 285 SUPERFAMILY SSF52540 3 207 6.82E-61 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1006 56426080836cea1a8d8d0add1d7cf242 285 Pfam PF13732 Domain of unknown function (DUF4162) 200 281 8.9E-7 T 31-10-2018 IPR025302 Domain of unknown function DUF4162 AF_1006 56426080836cea1a8d8d0add1d7cf242 285 Gene3D G3DSA:3.40.50.300 1 216 2.3E-62 T 31-10-2018 AF_0760 120c7bcc91e292e0a892ab8ba469dba3 959 SUPERFAMILY SSF53300 610 817 7.66E-11 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AF_0760 120c7bcc91e292e0a892ab8ba469dba3 959 Gene3D G3DSA:3.40.50.410 602 817 7.5E-19 T 31-10-2018 IPR036465 von Willebrand factor A-like domain superfamily AF_0844 8b187124395dd8da08acd3da5663125a 293 SUPERFAMILY SSF48452 75 268 1.64E-5 T 31-10-2018 IPR011990 Tetratricopeptide-like helical domain superfamily GO:0005515 AF_0999 26da69cf649e0f549976a1e2e323e6b5 218 Gene3D G3DSA:2.60.40.1120 22 93 1.9E-8 T 31-10-2018 AF_0999 26da69cf649e0f549976a1e2e323e6b5 218 Pfam PF13412 Winged helix-turn-helix DNA-binding 166 205 6.7E-5 T 31-10-2018 AF_0999 26da69cf649e0f549976a1e2e323e6b5 218 Gene3D G3DSA:1.10.10.10 147 218 1.7E-8 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0999 26da69cf649e0f549976a1e2e323e6b5 218 SUPERFAMILY SSF46785 155 217 2.96E-8 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0999 26da69cf649e0f549976a1e2e323e6b5 218 SUPERFAMILY SSF49464 22 98 1.02E-7 T 31-10-2018 IPR008969 Carboxypeptidase-like, regulatory domain superfamily AF_0769 04f11ccd2614cb7605f755a9581cda3c 93 Gene3D G3DSA:3.40.30.10 1 83 4.7E-16 T 31-10-2018 AF_0769 04f11ccd2614cb7605f755a9581cda3c 93 SUPERFAMILY SSF52833 1 82 8.85E-19 T 31-10-2018 IPR036249 Thioredoxin-like superfamily AF_0769 04f11ccd2614cb7605f755a9581cda3c 93 Pfam PF00085 Thioredoxin 3 70 2.7E-12 T 31-10-2018 IPR013766 Thioredoxin domain GO:0045454 AF_0417 97502a2e72ce2d1ce15ad28433e2a2d9 190 Pfam PF11655 Protein of unknown function (DUF2589) 14 177 1.2E-43 T 31-10-2018 IPR024510 Protein of unknown function DUF2589 AF_0417 97502a2e72ce2d1ce15ad28433e2a2d9 190 ProDom PD104924 XAC1607 AF0417 9 189 6.0E-89 T 31-10-2018 AF_1279 629e924f56a6c14653de4671fcb53add 249 Gene3D G3DSA:3.20.20.150 5 249 4.5E-39 T 31-10-2018 AF_1279 629e924f56a6c14653de4671fcb53add 249 Pfam PF01261 Xylose isomerase-like TIM barrel 13 213 2.1E-13 T 31-10-2018 IPR013022 Xylose isomerase-like, TIM barrel domain AF_1279 629e924f56a6c14653de4671fcb53add 249 SUPERFAMILY SSF51658 7 247 4.01E-29 T 31-10-2018 IPR036237 Xylose isomerase-like superfamily AF_0998 905d2b3794fb3083fb20c81aaf3d4cec 258 Pfam PF13412 Winged helix-turn-helix DNA-binding 9 54 8.9E-13 T 31-10-2018 AF_0998 905d2b3794fb3083fb20c81aaf3d4cec 258 PIRSF PIRSF004955 1 258 5.9E-102 T 31-10-2018 IPR012015 Uncharacterised conserved protein HTH transcriptional regulator, archaea AF_0998 905d2b3794fb3083fb20c81aaf3d4cec 258 SMART SM00419 17 66 2.3E-11 T 31-10-2018 IPR012318 Crp-type HTH domain GO:0003677|GO:0006355 AF_0998 905d2b3794fb3083fb20c81aaf3d4cec 258 Gene3D G3DSA:1.10.10.10 7 86 4.4E-10 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0998 905d2b3794fb3083fb20c81aaf3d4cec 258 SUPERFAMILY SSF46785 9 112 1.7E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0664 f1f64616de5e0ffedeeb32ab8c5cd932 402 Pfam PF01629 Domain of unknown function DUF22 4 111 5.5E-32 T 31-10-2018 IPR002572 Domain of unknown function DUF22 AF_0664 f1f64616de5e0ffedeeb32ab8c5cd932 402 Pfam PF01629 Domain of unknown function DUF22 149 252 5.4E-25 T 31-10-2018 IPR002572 Domain of unknown function DUF22 AF_0664 f1f64616de5e0ffedeeb32ab8c5cd932 402 Pfam PF01629 Domain of unknown function DUF22 289 381 9.4E-18 T 31-10-2018 IPR002572 Domain of unknown function DUF22 AF_2162 764e22723227b637b8ba2a32a7345b7a 177 SUPERFAMILY SSF160935 14 174 4.18E-25 T 31-10-2018 AF_2162 764e22723227b637b8ba2a32a7345b7a 177 PIRSF PIRSF010244 1 174 6.3E-73 T 31-10-2018 IPR014456 Uncharacterised conserved protein UCP010244, integral membrane protein AF_2162 764e22723227b637b8ba2a32a7345b7a 177 Pfam PF06863 Protein of unknown function (DUF1254) 45 170 3.3E-23 T 31-10-2018 IPR010679 Domain of unknown function DUF1254 AF_2335 c80012e88ebb1d3e231df7e7738bd84c 170 Gene3D G3DSA:3.40.50.850 1 170 4.0E-51 T 31-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AF_2335 c80012e88ebb1d3e231df7e7738bd84c 170 SUPERFAMILY SSF52499 2 169 1.96E-46 T 31-10-2018 IPR036380 Isochorismatase-like superfamily GO:0003824 AF_2335 c80012e88ebb1d3e231df7e7738bd84c 170 Pfam PF00857 Isochorismatase family 2 146 5.2E-33 T 31-10-2018 IPR000868 Isochorismatase-like GO:0003824 AF_1968 4dc650380af7b0960335542c111e9ff1 254 Gene3D G3DSA:3.30.420.40 1 81 1.3E-6 T 31-10-2018 AF_1968 4dc650380af7b0960335542c111e9ff1 254 ProSitePatterns PS01125 ROK family signature. 108 134 - T 31-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AF_1968 4dc650380af7b0960335542c111e9ff1 254 Pfam PF00480 ROK family 3 247 2.0E-25 T 31-10-2018 IPR000600 ROK family Reactome: R-HSA-4085001|Reactome: R-HSA-4085011 AF_1968 4dc650380af7b0960335542c111e9ff1 254 SUPERFAMILY SSF53067 1 249 6.92E-37 T 31-10-2018 AF_1968 4dc650380af7b0960335542c111e9ff1 254 Gene3D G3DSA:3.30.420.40 85 253 2.1E-29 T 31-10-2018 AF_1758 5280545b2187a1d1eed29cda2c8041f4 193 Pfam PF01364 Peptidase family C25 57 170 2.2E-6 T 31-10-2018 IPR001769 Gingipain GO:0006508|GO:0008234 AF_0353 0fd14b150d6d2b73684c94013826d61f 186 Gene3D G3DSA:3.40.50.300 33 186 7.1E-6 T 31-10-2018 AF_1830 61b3f2634a00a7b148d1f0542bd86247 413 SUPERFAMILY SSF56762 52 413 8.5E-100 T 31-10-2018 IPR029014 [NiFe]-hydrogenase, large subunit Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1830 61b3f2634a00a7b148d1f0542bd86247 413 Gene3D G3DSA:1.10.645.20 38 413 1.3E-120 T 31-10-2018 IPR038290 NADH-quinone oxidoreductase, subunit D superfamily Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_1830 61b3f2634a00a7b148d1f0542bd86247 413 Pfam PF00346 Respiratory-chain NADH dehydrogenase, 49 Kd subunit 153 413 5.9E-86 T 31-10-2018 IPR001135 NADH-quinone oxidoreductase, subunit D GO:0016651|GO:0048038|GO:0051287|GO:0055114 Reactome: R-HSA-611105|Reactome: R-HSA-6799198 AF_0108 315bf26c6180c4d9c360156f74d02621 265 Pfam PF01791 DeoC/LacD family aldolase 21 235 3.3E-67 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AF_0108 315bf26c6180c4d9c360156f74d02621 265 TIGRFAM TIGR01949 AroFGH_arch: predicted phospho-2-dehydro-3-deoxyheptonate aldolase 4 261 4.0E-117 T 31-10-2018 IPR010210 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase GO:0009073|GO:0016836 KEGG: 00400+2.2.1.10|MetaCyc: PWY-6160 AF_0108 315bf26c6180c4d9c360156f74d02621 265 Gene3D G3DSA:3.20.20.70 1 265 9.7E-95 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_0108 315bf26c6180c4d9c360156f74d02621 265 SMART SM01133 21 236 1.7E-68 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AF_0108 315bf26c6180c4d9c360156f74d02621 265 Hamap MF_00960 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase [aroA']. 3 264 65.398 T 31-10-2018 IPR010210 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase GO:0009073|GO:0016836 KEGG: 00400+2.2.1.10|MetaCyc: PWY-6160 AF_0108 315bf26c6180c4d9c360156f74d02621 265 SUPERFAMILY SSF51569 5 252 1.1E-81 T 31-10-2018 AF_0108 315bf26c6180c4d9c360156f74d02621 265 PIRSF PIRSF038992 1 265 8.8E-96 T 31-10-2018 IPR002915 DeoC/FbaB/ lacD aldolase GO:0016829 Reactome: R-HSA-6798695|Reactome: R-HSA-71336 AF_0933 f0d50855539c8ca9778591cec404cb63 290 TIGRFAM TIGR01122 ilvE_I: branched-chain amino acid aminotransferase 5 284 1.0E-123 T 31-10-2018 IPR005785 Branched-chain amino acid aminotransferase I GO:0004084|GO:0009081 KEGG: 00270+2.6.1.42|KEGG: 00280+2.6.1.42|KEGG: 00290+2.6.1.42|KEGG: 00770+2.6.1.42|KEGG: 00966+2.6.1.42|MetaCyc: PWY-5057|MetaCyc: PWY-5076|MetaCyc: PWY-5078|MetaCyc: PWY-5101|MetaCyc: PWY-5103|MetaCyc: PWY-5104|MetaCyc: PWY-5108|MetaCyc: PWY-7767 AF_0933 f0d50855539c8ca9778591cec404cb63 290 Gene3D G3DSA:3.30.470.10 1 125 3.3E-57 T 31-10-2018 AF_0933 f0d50855539c8ca9778591cec404cb63 290 Gene3D G3DSA:3.20.10.10 126 285 1.7E-56 T 31-10-2018 AF_0933 f0d50855539c8ca9778591cec404cb63 290 Pfam PF01063 Amino-transferase class IV 30 254 2.1E-59 T 31-10-2018 IPR001544 Aminotransferase class IV GO:0003824 Reactome: R-HSA-70895 AF_0933 f0d50855539c8ca9778591cec404cb63 290 ProSitePatterns PS00770 Aminotransferases class-IV signature. 183 211 - T 31-10-2018 IPR018300 Aminotransferase, class IV, conserved site GO:0003824 Reactome: R-HSA-70895 AF_0933 f0d50855539c8ca9778591cec404cb63 290 SUPERFAMILY SSF56752 3 280 3.92E-96 T 31-10-2018 IPR036038 Aminotransferase-like, PLP-dependent enzymes GO:0003824 Reactome: R-HSA-70895 AF_0103 351efdb647305edc8ddd38eb0df1b669 189 Gene3D G3DSA:3.40.1380.20 1 189 4.8E-89 T 31-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AF_0103 351efdb647305edc8ddd38eb0df1b669 189 Pfam PF02887 Pyruvate kinase, alpha/beta domain 17 165 9.1E-16 T 31-10-2018 IPR015795 Pyruvate kinase, C-terminal KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AF_0103 351efdb647305edc8ddd38eb0df1b669 189 SUPERFAMILY SSF52935 1 187 8.7E-70 T 31-10-2018 IPR036918 Pyruvate kinase, C-terminal domain superfamily KEGG: 00010+2.7.1.40|KEGG: 00230+2.7.1.40|KEGG: 00620+2.7.1.40|MetaCyc: PWY-1042|MetaCyc: PWY-2221|MetaCyc: PWY-5484|MetaCyc: PWY-5723|MetaCyc: PWY-6142|MetaCyc: PWY-6886|MetaCyc: PWY-6901|MetaCyc: PWY-7003|MetaCyc: PWY-7218|MetaCyc: PWY-7383|Reactome: R-HSA-70171 AF_0103 351efdb647305edc8ddd38eb0df1b669 189 PIRSF PIRSF016138 1 189 7.1E-95 T 31-10-2018 IPR015074 Protein of unknown function DUF1867 AF_0103 351efdb647305edc8ddd38eb0df1b669 189 ProDom PD022619 AF0103 MM1100 MJ0504 UNCHARACTERIZED SIMILAR MA4416 11 186 9.0E-97 T 31-10-2018 IPR015074 Protein of unknown function DUF1867 AF_0501 72e512c3b1da242584ab42eca68b1340 332 SUPERFAMILY SSF103501 2 278 8.5E-51 T 31-10-2018 IPR036197 NarG-like superfamily AF_0501 72e512c3b1da242584ab42eca68b1340 332 Gene3D G3DSA:1.20.950.20 73 263 1.9E-20 T 31-10-2018 AF_0501 72e512c3b1da242584ab42eca68b1340 332 Pfam PF02665 Nitrate reductase gamma subunit 98 256 5.3E-16 T 31-10-2018 IPR023234 NarG-like domain AF_2193 dd337a38777db178690b108b4f0b6d49 61 ProDom PD052873 AF2193 1 43 9.0E-19 T 31-10-2018 IPR035258 Protein of unknown function DUF5350 AF_2193 dd337a38777db178690b108b4f0b6d49 61 Pfam PF17299 Family of unknown function (DUF5350) 1 57 6.1E-27 T 31-10-2018 IPR035258 Protein of unknown function DUF5350 AF_2192 d41281886bfe70baa6b8f31aea8ef632 503 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 121 138 1.5E-21 T 31-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AF_2192 d41281886bfe70baa6b8f31aea8ef632 503 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 71 97 1.5E-21 T 31-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AF_2192 d41281886bfe70baa6b8f31aea8ef632 503 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 223 243 1.5E-21 T 31-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AF_2192 d41281886bfe70baa6b8f31aea8ef632 503 PRINTS PR01410 Cytochrome c-type biogenesis protein signature 189 215 1.5E-21 T 31-10-2018 IPR003567 Cytochrome c-type biogenesis protein GO:0015232|GO:0015886|GO:0016020|GO:0017004 AF_2192 d41281886bfe70baa6b8f31aea8ef632 503 Pfam PF01578 Cytochrome C assembly protein 80 264 9.2E-28 T 31-10-2018 IPR002541 Cytochrome c assembly protein GO:0017004|GO:0020037 AF_1251 534cf031408b433f8bccb501ab553a56 239 Gene3D G3DSA:3.40.50.10900 3 239 2.4E-61 T 31-10-2018 IPR038389 Proteasome assembly chaperone 2 superfamily AF_1251 534cf031408b433f8bccb501ab553a56 239 Pfam PF09754 PAC2 family 19 222 4.7E-46 T 31-10-2018 IPR019151 Proteasome assembly chaperone 2 AF_1251 534cf031408b433f8bccb501ab553a56 239 SUPERFAMILY SSF159659 4 231 1.83E-50 T 31-10-2018 AF_1251 534cf031408b433f8bccb501ab553a56 239 TIGRFAM TIGR00161 TIGR00161: TIGR00161 family protein 1 238 2.8E-122 T 31-10-2018 IPR004425 Conserved hypothetical protein CHP00061 AF_1392 68d8665a41a853f431f55ab2a37ec8a9 312 Pfam PF02653 Branched-chain amino acid transport system / permease component 14 292 2.4E-50 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AF_0277 7210598d1a046d2478ee71bddd20bc5f 629 SUPERFAMILY SSF55785 189 291 8.05E-14 T 31-10-2018 IPR035965 PAS domain superfamily AF_0277 7210598d1a046d2478ee71bddd20bc5f 629 Gene3D G3DSA:3.30.450.20 175 294 8.8E-13 T 31-10-2018 AF_0277 7210598d1a046d2478ee71bddd20bc5f 629 SUPERFAMILY SSF55785 302 412 1.42E-23 T 31-10-2018 IPR035965 PAS domain superfamily AF_0277 7210598d1a046d2478ee71bddd20bc5f 629 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 287 410 2.7E-32 T 31-10-2018 IPR000014 PAS domain AF_0277 7210598d1a046d2478ee71bddd20bc5f 629 TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein 183 290 8.9E-14 T 31-10-2018 IPR000014 PAS domain AF_0277 7210598d1a046d2478ee71bddd20bc5f 629 SMART SM00091 291 357 8.8E-9 T 31-10-2018 IPR000014 PAS domain AF_0277 7210598d1a046d2478ee71bddd20bc5f 629 SMART SM00091 168 236 0.04 T 31-10-2018 IPR000014 PAS domain AF_0277 7210598d1a046d2478ee71bddd20bc5f 629 SMART SM00091 69 131 37.0 T 31-10-2018 IPR000014 PAS domain AF_0277 7210598d1a046d2478ee71bddd20bc5f 629 Pfam PF13188 PAS domain 76 106 0.046 T 31-10-2018 IPR000014 PAS domain AF_0277 7210598d1a046d2478ee71bddd20bc5f 629 SUPERFAMILY SSF55781 397 538 7.63E-8 T 31-10-2018 AF_0277 7210598d1a046d2478ee71bddd20bc5f 629 Gene3D G3DSA:3.30.450.20 295 416 4.4E-26 T 31-10-2018 AF_0277 7210598d1a046d2478ee71bddd20bc5f 629 SMART SM00388 557 618 1.7E-5 T 31-10-2018 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain GO:0000155|GO:0007165 AF_0277 7210598d1a046d2478ee71bddd20bc5f 629 Pfam PF08447 PAS fold 203 262 1.4E-6 T 31-10-2018 IPR013655 PAS fold-3 GO:0005515 AF_0277 7210598d1a046d2478ee71bddd20bc5f 629 Pfam PF08448 PAS fold 298 404 1.2E-14 T 31-10-2018 IPR013656 PAS fold-4 AF_0277 7210598d1a046d2478ee71bddd20bc5f 629 SMART SM00086 362 403 1.5 T 31-10-2018 IPR001610 PAC motif AF_0277 7210598d1a046d2478ee71bddd20bc5f 629 SMART SM00086 243 283 15.0 T 31-10-2018 IPR001610 PAC motif AF_1801 4ab37b6258ae287c5f353ca7434416c1 226 Pfam PF00588 SpoU rRNA Methylase family 1 144 3.5E-30 T 31-10-2018 IPR001537 tRNA/rRNA methyltransferase, SpoU type GO:0003723|GO:0006396|GO:0008173 AF_1801 4ab37b6258ae287c5f353ca7434416c1 226 Gene3D G3DSA:3.40.1280.10 1 152 5.4E-43 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AF_1801 4ab37b6258ae287c5f353ca7434416c1 226 TIGRFAM TIGR00050 rRNA_methyl_1: RNA methyltransferase, TrmH family, group 1 1 221 8.7E-86 T 31-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 AF_1801 4ab37b6258ae287c5f353ca7434416c1 226 PIRSF PIRSF004808 1 225 9.8E-65 T 31-10-2018 IPR004384 RNA methyltransferase TrmJ/LasT GO:0006396|GO:0008173 AF_1801 4ab37b6258ae287c5f353ca7434416c1 226 SUPERFAMILY SSF75217 1 146 6.54E-30 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases AF_1590 048c9e352ef52f88c7d02ccc8202100e 391 Pfam PF04895 Archaeal Nre, C-terminal 282 390 2.5E-37 T 31-10-2018 IPR006979 Archaeal Nre, C-terminal AF_1590 048c9e352ef52f88c7d02ccc8202100e 391 Pfam PF04894 Archaeal Nre, N-terminal 11 270 1.7E-97 T 31-10-2018 IPR006978 Archaeal Nre, N-terminal AF_1590 048c9e352ef52f88c7d02ccc8202100e 391 Hamap MF_02096 DNA repair protein. 1 390 37.853 T 31-10-2018 IPR033167 Archaeal Nre GO:0006281 AF_1163 0e16d65f54f8847e90ffe5dc9858413d 188 Pfam PF01991 ATP synthase (E/31 kDa) subunit 9 187 4.9E-46 T 31-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AF_1163 0e16d65f54f8847e90ffe5dc9858413d 188 Hamap MF_00311 V-type proton ATPase subunit E [atpE]. 1 188 14.168 T 31-10-2018 IPR002842 V-type ATPase subunit E GO:0015991|GO:0033178|GO:0046961 Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AF_1163 0e16d65f54f8847e90ffe5dc9858413d 188 SUPERFAMILY SSF160527 80 187 2.22E-23 T 31-10-2018 AF_1163 0e16d65f54f8847e90ffe5dc9858413d 188 Gene3D G3DSA:3.30.2320.30 80 187 1.2E-19 T 31-10-2018 IPR038495 V-type ATPase subunit E, C-terminal domain superfamily Reactome: R-HSA-1222556|Reactome: R-HSA-77387|Reactome: R-HSA-917977|Reactome: R-HSA-983712 AF_2194 9ed11c595e0b2e9533ae33943e289bfb 180 Pfam PF08241 Methyltransferase domain 43 126 9.4E-12 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AF_2194 9ed11c595e0b2e9533ae33943e289bfb 180 SUPERFAMILY SSF53335 22 154 3.67E-23 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_2194 9ed11c595e0b2e9533ae33943e289bfb 180 Gene3D G3DSA:3.40.50.150 1 178 2.3E-38 T 31-10-2018 AF_1822 803427bd9ab2b6a0db78903bd141a3bb 268 Gene3D G3DSA:3.60.21.10 1 249 9.1E-47 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like AF_1822 803427bd9ab2b6a0db78903bd141a3bb 268 SUPERFAMILY SSF56300 2 232 2.76E-44 T 31-10-2018 AF_1822 803427bd9ab2b6a0db78903bd141a3bb 268 PRINTS PR00114 Serine/threonine phosphatase family signature 51 78 3.9E-10 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AF_1822 803427bd9ab2b6a0db78903bd141a3bb 268 PRINTS PR00114 Serine/threonine phosphatase family signature 118 144 3.9E-10 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AF_1822 803427bd9ab2b6a0db78903bd141a3bb 268 PRINTS PR00114 Serine/threonine phosphatase family signature 147 174 3.9E-10 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AF_1822 803427bd9ab2b6a0db78903bd141a3bb 268 Pfam PF00149 Calcineurin-like phosphoesterase 27 215 5.4E-20 T 31-10-2018 IPR004843 Calcineurin-like phosphoesterase domain, ApaH type GO:0016787 AF_1822 803427bd9ab2b6a0db78903bd141a3bb 268 SMART SM00156 1 255 5.1E-13 T 31-10-2018 IPR006186 Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase GO:0016787 KEGG: 04658+3.1.3.16|KEGG: 04660+3.1.3.16 AF_0576 fefbbf45a4bd7cbe46139541ed942a9e 86 TIGRFAM TIGR04140 chp_AF_0576: TIGR04140 family protein 17 86 2.3E-26 T 31-10-2018 IPR026486 Uncharacterised protein AF_0576 AF_0449 dcbd8b135de29534ab7e6e1232ed87f2 125 SMART SM00448 11 120 1.5E-29 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_0449 dcbd8b135de29534ab7e6e1232ed87f2 125 Gene3D G3DSA:3.40.50.2300 8 125 1.7E-34 T 31-10-2018 AF_0449 dcbd8b135de29534ab7e6e1232ed87f2 125 SUPERFAMILY SSF52172 9 125 4.55E-33 T 31-10-2018 IPR011006 CheY-like superfamily AF_0449 dcbd8b135de29534ab7e6e1232ed87f2 125 Pfam PF00072 Response regulator receiver domain 13 120 3.3E-25 T 31-10-2018 IPR001789 Signal transduction response regulator, receiver domain GO:0000160 AF_0418 40963f47f5d0463e7855dd9785454af4 179 SUPERFAMILY SSF56112 11 159 1.63E-10 T 31-10-2018 IPR011009 Protein kinase-like domain superfamily AF_0217 ff978933470bb4285181d232cfb33842 377 Gene3D G3DSA:1.20.1530.20 3 373 4.2E-56 T 31-10-2018 IPR038770 Sodium/solute symporter superfamily AF_0217 ff978933470bb4285181d232cfb33842 377 Pfam PF00999 Sodium/hydrogen exchanger family 11 365 2.1E-56 T 31-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AF_0300 6386444922c06b9e4bd2f3bfab9afabf 50 Pfam PF01850 PIN domain 2 36 5.1E-7 T 31-10-2018 IPR002716 PIN domain AF_0300 6386444922c06b9e4bd2f3bfab9afabf 50 Gene3D G3DSA:3.40.50.1010 1 48 2.7E-7 T 31-10-2018 AF_0300 6386444922c06b9e4bd2f3bfab9afabf 50 SUPERFAMILY SSF88723 4 43 2.45E-9 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_2257 83835eea0069218f6fa29b89a21ed746 348 PIRSF PIRSF016817 1 348 3.0E-117 T 31-10-2018 IPR016677 Uncharacterised conserved protein UCP016817, ATP-dependent carboligase AF_2257 83835eea0069218f6fa29b89a21ed746 348 Pfam PF02655 ATP-grasp domain 97 247 1.9E-40 T 31-10-2018 IPR003806 ATP-grasp fold, DUF201-type GO:0005524|GO:0046872 AF_2257 83835eea0069218f6fa29b89a21ed746 348 Gene3D G3DSA:3.30.470.20 94 249 3.0E-29 T 31-10-2018 AF_2257 83835eea0069218f6fa29b89a21ed746 348 Gene3D G3DSA:3.30.1490.350 115 153 3.0E-29 T 31-10-2018 AF_2257 83835eea0069218f6fa29b89a21ed746 348 SUPERFAMILY SSF56059 97 283 4.77E-24 T 31-10-2018 AF_1495 8020ff5b090ed6825049dbb0efad2d50 137 Hamap MF_01222 Protein archease. 1 137 40.494 T 31-10-2018 IPR022952 Archease, archaea AF_1495 8020ff5b090ed6825049dbb0efad2d50 137 Gene3D G3DSA:3.55.10.10 1 137 1.9E-39 T 31-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 AF_1495 8020ff5b090ed6825049dbb0efad2d50 137 SUPERFAMILY SSF69819 1 137 6.54E-40 T 31-10-2018 IPR036820 Archease domain superfamily Reactome: R-HSA-6784531 AF_1495 8020ff5b090ed6825049dbb0efad2d50 137 Pfam PF01951 Archease protein family (MTH1598/TM1083) 3 137 8.4E-39 T 31-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 AF_1495 8020ff5b090ed6825049dbb0efad2d50 137 ProDom PD012969 UPF0211 RIKEN CDNA ENRICHED MALE FULL-LENGTH LIBRARY ZBTB8OS ADULT C43H8.1 7 136 2.0E-43 T 31-10-2018 IPR023572 Archease domain Reactome: R-HSA-6784531 AF_2435 39c6c8906445976ef8c1d70c694dfe5d 322 Gene3D G3DSA:3.100.10.20 1 82 8.0E-32 T 31-10-2018 AF_2435 39c6c8906445976ef8c1d70c694dfe5d 322 TIGRFAM TIGR03641 cas1_HMARI: CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP 4 322 6.9E-147 T 31-10-2018 IPR019858 CRISPR-associated protein Cas1, HMARI/TNEAP subtype GO:0004520|GO:0043571|GO:0046872 AF_2435 39c6c8906445976ef8c1d70c694dfe5d 322 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 2 307 28.588 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 AF_2435 39c6c8906445976ef8c1d70c694dfe5d 322 Pfam PF01867 CRISPR associated protein Cas1 6 277 1.2E-90 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 AF_2435 39c6c8906445976ef8c1d70c694dfe5d 322 Gene3D G3DSA:1.20.120.920 83 321 6.8E-76 T 31-10-2018 AF_2435 39c6c8906445976ef8c1d70c694dfe5d 322 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 7 317 3.2E-105 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 AF_1868 f483b2832878c4005db0617907a5361c 329 TIGRFAM TIGR01894 cas_TM1795_cmr1: CRISPR type III-B/RAMP module RAMP protein Cmr1 10 157 2.6E-42 T 31-10-2018 IPR007522 CRISPR-associated protein TM1795 AF_1868 f483b2832878c4005db0617907a5361c 329 Pfam PF03787 RAMP superfamily 9 154 9.2E-13 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein AF_2169 9551ea757a264cfb7188ca861802b2eb 136 Gene3D G3DSA:1.20.120.580 1 136 3.2E-6 T 31-10-2018 IPR037038 Bsu32300-like superfamily AF_2169 9551ea757a264cfb7188ca861802b2eb 136 Pfam PF01934 Protein of unknown function DUF86 28 127 2.0E-18 T 31-10-2018 IPR008201 Protein of unknown function DUF86 AF_1427 eddcb593fc2f34ef48bc4f89d27baad8 71 Pfam PF09947 Uncharacterized protein conserved in archaea (DUF2180) 3 69 4.6E-37 T 31-10-2018 IPR017211 Uncharacterised conserved protein UCP037465, zinc finger protein, AF1427 AF_1427 eddcb593fc2f34ef48bc4f89d27baad8 71 PIRSF PIRSF037465 1 71 1.7E-38 T 31-10-2018 IPR017211 Uncharacterised conserved protein UCP037465, zinc finger protein, AF1427 AF_1427 eddcb593fc2f34ef48bc4f89d27baad8 71 SUPERFAMILY SSF57903 4 67 1.94E-5 T 31-10-2018 IPR011011 Zinc finger, FYVE/PHD-type AF_0579 54372358a9f02240b76557777a087f73 307 SUPERFAMILY SSF55785 22 125 4.03E-10 T 31-10-2018 IPR035965 PAS domain superfamily AF_0579 54372358a9f02240b76557777a087f73 307 Gene3D G3DSA:3.30.450.20 4 128 4.3E-11 T 31-10-2018 AF_1292 b589b27e138925573c4fb35ed89287a3 136 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 45 110 7.2E-19 T 31-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AF_1292 b589b27e138925573c4fb35ed89287a3 136 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 7 43 2.5E-12 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AF_1292 b589b27e138925573c4fb35ed89287a3 136 Gene3D G3DSA:1.10.12.20 3 47 1.0E-9 T 31-10-2018 AF_1292 b589b27e138925573c4fb35ed89287a3 136 SUPERFAMILY SSF50249 6 118 2.23E-30 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_1703 013299fc79e55e1cf466eac2b6e45ff9 208 Pfam PF01810 LysE type translocator 15 198 5.0E-43 T 31-10-2018 IPR001123 Amino acid exporter protein, LeuE-type GO:0006865|GO:0016020 AF_0005 0f9961a3eb04c8f40df643de5b3c1810 197 Pfam PF01402 Ribbon-helix-helix protein, copG family 6 43 8.1E-11 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 AF_0026 8c7d0da7eba93eb195b3c07ad50bab08 216 Pfam PF11495 Archaeal transcriptional regulator TrmB 86 213 2.8E-7 T 31-10-2018 IPR021586 Transcription regulator TrmB, C-terminal AF_0026 8c7d0da7eba93eb195b3c07ad50bab08 216 Gene3D G3DSA:1.10.10.10 1 69 3.5E-8 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1978 cc6c96ab9351988de7a44369941a6e9d 102 Pfam PF03091 CutA1 divalent ion tolerance protein 4 99 3.6E-37 T 31-10-2018 IPR004323 Divalent ion tolerance protein, CutA GO:0010038 AF_1978 cc6c96ab9351988de7a44369941a6e9d 102 SUPERFAMILY SSF54913 4 101 2.34E-36 T 31-10-2018 IPR011322 Nitrogen regulatory PII-like, alpha/beta AF_1978 cc6c96ab9351988de7a44369941a6e9d 102 Gene3D G3DSA:3.30.70.120 1 102 3.0E-42 T 31-10-2018 IPR015867 Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal AF_2081 e1c6fc797752f311b02ea47e96c07bfc 196 Pfam PF06510 Protein of unknown function (DUF1102) 38 183 8.9E-58 T 31-10-2018 IPR009482 Protein of unknown function DUF1102 AF_0022 272e7b1d4f37db59eae0cea29aff291d 91 Gene3D G3DSA:3.10.20.30 1 91 4.2E-12 T 31-10-2018 IPR012675 Beta-grasp domain superfamily AF_0022 272e7b1d4f37db59eae0cea29aff291d 91 SUPERFAMILY SSF54285 1 91 1.39E-11 T 31-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AF_0022 272e7b1d4f37db59eae0cea29aff291d 91 Pfam PF02597 ThiS family 17 91 1.3E-13 T 31-10-2018 IPR003749 Sulfur carrier ThiS/MoaD-like Reactome: R-HSA-947581 AF_1382 0197540c15dec10b4acd329465945d8f 95 SUPERFAMILY SSF46785 12 93 5.73E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1382 0197540c15dec10b4acd329465945d8f 95 Gene3D G3DSA:1.10.10.10 1 95 7.6E-32 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1188 42ab5e76d1ee6badb2e55b4056d4572b 175 PIRSF PIRSF030780 1 173 8.3E-18 T 31-10-2018 IPR016956 Inner membrane protein YdjM AF_1188 42ab5e76d1ee6badb2e55b4056d4572b 175 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 2 165 1.8E-30 T 31-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase AF_1347 6057d52230a028b04c0a3ba1d62b28e0 123 Pfam PF04895 Archaeal Nre, C-terminal 19 108 9.1E-32 T 31-10-2018 IPR006979 Archaeal Nre, C-terminal AF_0056 6842ab070c69cbe8f40d876611882564 46 Hamap MF_00615 DNA-directed RNA polymerase subunit P [rpoP]. 3 46 14.216 T 31-10-2018 IPR023464 DNA-directed RNA polymerase subunit P (Rpo12) GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6 AF_0056 6842ab070c69cbe8f40d876611882564 46 Pfam PF03604 DNA directed RNA polymerase, 7 kDa subunit 3 35 1.1E-8 T 31-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AF_0056 6842ab070c69cbe8f40d876611882564 46 SUPERFAMILY SSF63393 1 38 1.31E-9 T 31-10-2018 IPR029040 RNA polymerase subunit RPABC4/transcription elongation factor Spt4 Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-674695|Reactome: R-HSA-6796648|Reactome: R-HSA-6807505|Reactome: R-HSA-75955 AF_0056 6842ab070c69cbe8f40d876611882564 46 SMART SM00659 1 46 1.0E-20 T 31-10-2018 IPR006591 RNA polymerase archaeal subunit P/eukaryotic subunit RPABC4 GO:0003677|GO:0003899|GO:0006351 KEGG: 00230+2.7.7.6|KEGG: 00240+2.7.7.6|Reactome: R-HSA-112382|Reactome: R-HSA-113418|Reactome: R-HSA-167152|Reactome: R-HSA-167158|Reactome: R-HSA-167160|Reactome: R-HSA-167161|Reactome: R-HSA-167162|Reactome: R-HSA-167172|Reactome: R-HSA-167200|Reactome: R-HSA-167238|Reactome: R-HSA-167242|Reactome: R-HSA-167243|Reactome: R-HSA-167246|Reactome: R-HSA-167287|Reactome: R-HSA-167290|Reactome: R-HSA-168325|Reactome: R-HSA-1834949|Reactome: R-HSA-203927|Reactome: R-HSA-427413|Reactome: R-HSA-452723|Reactome: R-HSA-5250924|Reactome: R-HSA-5578749|Reactome: R-HSA-5601884|Reactome: R-HSA-5617472|Reactome: R-HSA-674695|Reactome: R-HSA-6781823|Reactome: R-HSA-6781827|Reactome: R-HSA-6782135|Reactome: R-HSA-6782210|Reactome: R-HSA-6796648|Reactome: R-HSA-6803529|Reactome: R-HSA-6807505|Reactome: R-HSA-72086|Reactome: R-HSA-72163|Reactome: R-HSA-72165|Reactome: R-HSA-72203|Reactome: R-HSA-73762|Reactome: R-HSA-73772|Reactome: R-HSA-73776|Reactome: R-HSA-73777|Reactome: R-HSA-73779|Reactome: R-HSA-73780|Reactome: R-HSA-73863|Reactome: R-HSA-73980|Reactome: R-HSA-749476|Reactome: R-HSA-75953|Reactome: R-HSA-75955|Reactome: R-HSA-76042|Reactome: R-HSA-76061|Reactome: R-HSA-76066|Reactome: R-HSA-76071|Reactome: R-HSA-77075|Reactome: R-HSA-8851708|Reactome: R-HSA-9018519 AF_0056 6842ab070c69cbe8f40d876611882564 46 Gene3D G3DSA:2.20.28.30 1 46 1.2E-16 T 31-10-2018 AF_1905 0b620643fb2c47bdcc0a5e023f511098 198 SUPERFAMILY SSF54768 40 111 6.91E-22 T 31-10-2018 AF_1905 0b620643fb2c47bdcc0a5e023f511098 198 Pfam PF00333 Ribosomal protein S5, N-terminal domain 46 110 5.1E-26 T 31-10-2018 IPR013810 Ribosomal protein S5, N-terminal GO:0003723|GO:0003735|GO:0005840|GO:0006412 AF_1905 0b620643fb2c47bdcc0a5e023f511098 198 Pfam PF03719 Ribosomal protein S5, C-terminal domain 131 194 1.7E-21 T 31-10-2018 IPR005324 Ribosomal protein S5, C-terminal GO:0003735|GO:0005840|GO:0006412 AF_1905 0b620643fb2c47bdcc0a5e023f511098 198 Gene3D G3DSA:3.30.230.10 109 197 1.3E-31 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AF_1905 0b620643fb2c47bdcc0a5e023f511098 198 SUPERFAMILY SSF54211 124 196 1.77E-20 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AF_1905 0b620643fb2c47bdcc0a5e023f511098 198 Hamap MF_01307_A 30S ribosomal protein S5 [rpsE]. 1 198 49.982 T 31-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1905 0b620643fb2c47bdcc0a5e023f511098 198 TIGRFAM TIGR01020 uS5_euk_arch: ribosomal protein uS5 2 197 4.6E-106 T 31-10-2018 IPR005711 Ribosomal protein S5, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015935 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-3214858|Reactome: R-HSA-6790901|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-8876725|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1905 0b620643fb2c47bdcc0a5e023f511098 198 ProSitePatterns PS00585 Ribosomal protein S5 signature. 63 95 - T 31-10-2018 IPR018192 Ribosomal protein S5, N-terminal, conserved site AF_1905 0b620643fb2c47bdcc0a5e023f511098 198 Gene3D G3DSA:3.30.160.770 4 107 3.2E-41 T 31-10-2018 AF_2132 03401f2d52beb939f53425da33f653f1 244 ProDom PD359573 MEMBRANE TRANSMEMBRANE AF2132 PROTEIN 3 242 8.0E-103 T 31-10-2018 AF_0415 33f31315864bdcf89a759cfe57399b2c 68 ProDom PD104924 XAC1607 AF0417 6 37 2.0E-4 T 31-10-2018 AF_0415 33f31315864bdcf89a759cfe57399b2c 68 Pfam PF11655 Protein of unknown function (DUF2589) 3 58 7.3E-9 T 31-10-2018 IPR024510 Protein of unknown function DUF2589 AF_0225 0e583a6b1692eab1e17d93603864416f 338 Pfam PF02653 Branched-chain amino acid transport system / permease component 53 320 1.2E-49 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AF_2175 7b55f70295eba394434083ac38c5cf5f 273 Pfam PF09810 Exonuclease V - a 5' deoxyribonuclease 194 272 1.3E-10 T 31-10-2018 IPR019190 Exonuclease V GO:0045145 AF_2175 7b55f70295eba394434083ac38c5cf5f 273 Pfam PF09810 Exonuclease V - a 5' deoxyribonuclease 3 118 5.3E-8 T 31-10-2018 IPR019190 Exonuclease V GO:0045145 AF_0963 b94c1ace881e44ccb14833daabd7c206 259 ProSitePatterns PS00166 Enoyl-CoA hydratase/isomerase signature. 98 118 - T 31-10-2018 IPR018376 Enoyl-CoA hydratase/isomerase, conserved site GO:0003824 AF_0963 b94c1ace881e44ccb14833daabd7c206 259 Gene3D G3DSA:1.10.12.10 200 255 1.4E-20 T 31-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AF_0963 b94c1ace881e44ccb14833daabd7c206 259 Gene3D G3DSA:3.90.226.10 1 198 9.2E-79 T 31-10-2018 AF_0963 b94c1ace881e44ccb14833daabd7c206 259 Pfam PF00378 Enoyl-CoA hydratase/isomerase 8 255 1.5E-78 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AF_0963 b94c1ace881e44ccb14833daabd7c206 259 SUPERFAMILY SSF52096 3 256 7.47E-96 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AF_1932 e54e8d32341d2a64bea8a66080bd7f77 509 Gene3D G3DSA:3.30.300.30 405 506 2.1E-22 T 31-10-2018 AF_1932 e54e8d32341d2a64bea8a66080bd7f77 509 Pfam PF13193 AMP-binding enzyme C-terminal domain 418 493 3.6E-16 T 31-10-2018 IPR025110 AMP-binding enzyme, C-terminal domain AF_1932 e54e8d32341d2a64bea8a66080bd7f77 509 SUPERFAMILY SSF56801 6 506 1.83E-129 T 31-10-2018 AF_1932 e54e8d32341d2a64bea8a66080bd7f77 509 ProSitePatterns PS00455 Putative AMP-binding domain signature. 163 174 - T 31-10-2018 IPR020845 AMP-binding, conserved site AF_1932 e54e8d32341d2a64bea8a66080bd7f77 509 Pfam PF00501 AMP-binding enzyme 13 409 2.2E-90 T 31-10-2018 IPR000873 AMP-dependent synthetase/ligase GO:0003824 AF_1932 e54e8d32341d2a64bea8a66080bd7f77 509 Gene3D G3DSA:3.40.50.12780 4 404 3.5E-96 T 31-10-2018 AF_1593 2979f1272088e0a69bd8c481911ca454 72 SUPERFAMILY SSF46785 3 60 1.06E-6 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1593 2979f1272088e0a69bd8c481911ca454 72 Gene3D G3DSA:1.10.10.2890 2 67 1.0E-8 T 31-10-2018 AF_1332 4def361e2b374ac84d3dcfdbbcc2cc2e 182 Gene3D G3DSA:1.20.58.1030 1 115 7.1E-9 T 31-10-2018 AF_1598 c9c21fbb2c3f0e8959fc8a13aed92449 103 Pfam PF14018 Domain of unknown function (DUF4234) 5 60 8.4E-11 T 31-10-2018 IPR025328 Domain of unknown function DUF4234 AF_0174 67757d8786bea5373656ab3e711be853 407 Pfam PF03916 Polysulphide reductase, NrfD 31 338 9.4E-78 T 31-10-2018 IPR005614 NrfD family AF_1504 ca7e83bcc43d1f654b0598a7b5d8589a 201 Pfam PF02359 Cell division protein 48 (CDC48), N-terminal domain 135 198 3.5E-6 T 31-10-2018 IPR003338 CDC48, N-terminal subdomain AF_1504 ca7e83bcc43d1f654b0598a7b5d8589a 201 Gene3D G3DSA:2.40.40.20 121 201 1.6E-6 T 31-10-2018 AF_1504 ca7e83bcc43d1f654b0598a7b5d8589a 201 SUPERFAMILY SSF50692 125 199 2.61E-6 T 31-10-2018 IPR009010 Aspartate decarboxylase-like domain superfamily AF_2218 214125b308afb762c4bac47240e592f0 131 SUPERFAMILY SSF54593 2 130 9.63E-33 T 31-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AF_2218 214125b308afb762c4bac47240e592f0 131 Gene3D G3DSA:3.10.180.10 1 130 5.5E-41 T 31-10-2018 IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase AF_2218 214125b308afb762c4bac47240e592f0 131 TIGRFAM TIGR03081 metmalonyl_epim: methylmalonyl-CoA epimerase 4 130 6.8E-53 T 31-10-2018 IPR017515 Methylmalonyl-CoA epimerase KEGG: 00280+5.1.99.1|KEGG: 00630+5.1.99.1|KEGG: 00640+5.1.99.1|KEGG: 00720+5.1.99.1|MetaCyc: PWY-5741|MetaCyc: PWY-5743|MetaCyc: PWY-5789|MetaCyc: PWY-6728|MetaCyc: PWY-7384|MetaCyc: PWY-7854|Reactome: R-HSA-71032 AF_2218 214125b308afb762c4bac47240e592f0 131 Pfam PF13669 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily 6 115 5.3E-24 T 31-10-2018 AF_0412 f35d0f92d5ea8daf536aea33605b6628 148 Pfam PF04307 LexA-binding, inner membrane-associated putative hydrolase 9 126 1.8E-13 T 31-10-2018 IPR007404 LexA-binding, inner membrane-associated putative hydrolase AF_1207 66e027a2c13c1673439c08b7a93eb32d 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 206 223 1.5E-37 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AF_1207 66e027a2c13c1673439c08b7a93eb32d 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 241 261 1.5E-37 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AF_1207 66e027a2c13c1673439c08b7a93eb32d 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 158 174 1.5E-37 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AF_1207 66e027a2c13c1673439c08b7a93eb32d 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 111 122 1.5E-37 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AF_1207 66e027a2c13c1673439c08b7a93eb32d 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 185 204 1.5E-37 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AF_1207 66e027a2c13c1673439c08b7a93eb32d 281 PRINTS PR00081 Glucose/ribitol dehydrogenase family signature 37 54 1.5E-37 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AF_1207 66e027a2c13c1673439c08b7a93eb32d 281 ProSitePatterns PS00061 Short-chain dehydrogenases/reductases family signature. 172 200 - T 31-10-2018 IPR020904 Short-chain dehydrogenase/reductase, conserved site GO:0016491 AF_1207 66e027a2c13c1673439c08b7a93eb32d 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 164 172 1.3E-11 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AF_1207 66e027a2c13c1673439c08b7a93eb32d 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 111 122 1.3E-11 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AF_1207 66e027a2c13c1673439c08b7a93eb32d 281 PRINTS PR00080 Short-chain dehydrogenase/reductase (SDR) superfamily signature 185 204 1.3E-11 T 31-10-2018 IPR002347 Short-chain dehydrogenase/reductase SDR AF_1207 66e027a2c13c1673439c08b7a93eb32d 281 SUPERFAMILY SSF51735 30 279 1.53E-90 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_1207 66e027a2c13c1673439c08b7a93eb32d 281 Gene3D G3DSA:3.40.50.720 15 280 6.0E-90 T 31-10-2018 AF_1207 66e027a2c13c1673439c08b7a93eb32d 281 SMART SM00822 This enzymatic domain is part of bacterial polyketide synthases and catalyses the first step in the reductive modification of the beta-carbonyl centres in the growing polyketide chain. It uses NADPH to reduce the keto group to a hydroxy group. 36 216 0.0041 T 31-10-2018 AF_1207 66e027a2c13c1673439c08b7a93eb32d 281 Pfam PF13561 Enoyl-(Acyl carrier protein) reductase 42 278 1.3E-68 T 31-10-2018 AF_1541 214275eed069906f6201505eaf4cad5c 372 Pfam PF07690 Major Facilitator Superfamily 28 220 6.4E-12 T 31-10-2018 IPR011701 Major facilitator superfamily GO:0016021|GO:0055085 AF_1541 214275eed069906f6201505eaf4cad5c 372 Gene3D G3DSA:1.20.1250.20 200 371 2.1E-13 T 31-10-2018 AF_1541 214275eed069906f6201505eaf4cad5c 372 SUPERFAMILY SSF103473 8 367 1.28E-35 T 31-10-2018 IPR036259 MFS transporter superfamily AF_1541 214275eed069906f6201505eaf4cad5c 372 Gene3D G3DSA:1.20.1250.20 2 196 1.1E-17 T 31-10-2018 AF_0711 2cac4ce48ec802cb77149da795eceda7 119 Gene3D G3DSA:3.40.30.10 27 119 6.1E-15 T 31-10-2018 AF_0711 2cac4ce48ec802cb77149da795eceda7 119 Pfam PF00085 Thioredoxin 29 104 4.6E-11 T 31-10-2018 IPR013766 Thioredoxin domain GO:0045454 AF_0711 2cac4ce48ec802cb77149da795eceda7 119 SUPERFAMILY SSF52833 31 110 6.26E-14 T 31-10-2018 IPR036249 Thioredoxin-like superfamily AF_1260 35e2052c42af24039ac8b8c24ef120cf 271 PIRSF PIRSF001586 4 271 3.4E-84 T 31-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AF_1260 35e2052c42af24039ac8b8c24ef120cf 271 SMART SM01211 5 268 3.9E-105 T 31-10-2018 AF_1260 35e2052c42af24039ac8b8c24ef120cf 271 Pfam PF13507 CobB/CobQ-like glutamine amidotransferase domain 6 267 1.7E-64 T 31-10-2018 AF_1260 35e2052c42af24039ac8b8c24ef120cf 271 Hamap MF_00421 Phosphoribosylformylglycinamidine synthase subunit PurQ [purQ]. 6 266 36.232 T 31-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AF_1260 35e2052c42af24039ac8b8c24ef120cf 271 Gene3D G3DSA:3.40.50.880 1 268 9.9E-78 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_1260 35e2052c42af24039ac8b8c24ef120cf 271 TIGRFAM TIGR01737 FGAM_synth_I: phosphoribosylformylglycinamidine synthase I 6 267 1.2E-97 T 31-10-2018 IPR010075 Phosphoribosylformylglycinamidine synthase subunit PurQ GO:0004642|GO:0005737|GO:0006189 KEGG: 00220+3.5.1.2|KEGG: 00230+6.3.5.3|KEGG: 00250+3.5.1.2|KEGG: 00471+3.5.1.2|MetaCyc: PWY-6121|MetaCyc: PWY-6122|MetaCyc: PWY-6277 AF_1260 35e2052c42af24039ac8b8c24ef120cf 271 SUPERFAMILY SSF52317 5 268 6.02E-71 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_1295 76af8e65b719780c249ff3aa56cb5d68 137 Pfam PF10865 Domain of unknown function (DUF2703) 3 118 2.5E-37 T 31-10-2018 IPR021219 Protein of unknown function DUF2703 AF_0924 7966ec7b6b80eefadeb7d792f0b4808c 195 Gene3D G3DSA:1.10.3940.10 63 195 2.7E-91 T 31-10-2018 AF_1688 fda7344cae07390285488376023d56ae 274 Pfam PF01925 Sulfite exporter TauE/SafE 9 264 1.8E-34 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AF_0801 320b2f427d93a83f5ac89515f18a8ac6 152 Gene3D G3DSA:1.10.287.10 82 150 2.6E-26 T 31-10-2018 AF_0801 320b2f427d93a83f5ac89515f18a8ac6 152 ProSitePatterns PS00362 Ribosomal protein S15 signature. 98 128 - T 31-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_0801 320b2f427d93a83f5ac89515f18a8ac6 152 Pfam PF08069 Ribosomal S13/S15 N-terminal domain 1 60 2.0E-27 T 31-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0801 320b2f427d93a83f5ac89515f18a8ac6 152 SMART SM01386 1 60 3.4E-33 T 31-10-2018 IPR012606 Ribosomal protein S13/S15, N-terminal GO:0003735|GO:0005840|GO:0006412 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0801 320b2f427d93a83f5ac89515f18a8ac6 152 SUPERFAMILY SSF47060 66 146 9.12E-21 T 31-10-2018 IPR009068 S15/NS1, RNA-binding AF_0801 320b2f427d93a83f5ac89515f18a8ac6 152 Hamap MF_01343_A 30S ribosomal protein S15 [rpsO]. 3 149 35.702 T 31-10-2018 IPR023029 Ribosomal protein S15P Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72649|Reactome: R-HSA-72689|Reactome: R-HSA-72695|Reactome: R-HSA-72702|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_0801 320b2f427d93a83f5ac89515f18a8ac6 152 Gene3D G3DSA:1.10.8.1030 35 81 3.3E-19 T 31-10-2018 AF_0801 320b2f427d93a83f5ac89515f18a8ac6 152 Pfam PF00312 Ribosomal protein S15 73 148 3.1E-15 T 31-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_0801 320b2f427d93a83f5ac89515f18a8ac6 152 SMART SM01387 70 149 5.6E-17 T 31-10-2018 IPR000589 Ribosomal protein S15 GO:0003735|GO:0005622|GO:0005840|GO:0006412 AF_2411 1d0ea2c274b525d68efa52eb9fec3e02 363 SUPERFAMILY SSF51679 1 345 4.58E-64 T 31-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AF_2411 1d0ea2c274b525d68efa52eb9fec3e02 363 Pfam PF00296 Luciferase-like monooxygenase 1 334 1.7E-87 T 31-10-2018 IPR011251 Luciferase-like domain GO:0016705|GO:0055114 AF_2411 1d0ea2c274b525d68efa52eb9fec3e02 363 Gene3D G3DSA:3.20.20.30 1 363 9.9E-79 T 31-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AF_1661 12523b2e98c7d87775b7ff01c6e0fde6 250 Pfam PF12389 Camelysin metallo-endopeptidase 13 46 4.1E-6 T 31-10-2018 IPR022121 Peptidase M73, camelysin AF_1661 12523b2e98c7d87775b7ff01c6e0fde6 250 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 9 41 4.0E-11 T 31-10-2018 IPR023833 Signal peptide, camelysin AF_1953 b393b76668cf0e648916ccd624c131d2 247 SUPERFAMILY SSF56300 3 244 1.02E-29 T 31-10-2018 AF_1953 b393b76668cf0e648916ccd624c131d2 247 Gene3D G3DSA:3.60.21.10 2 241 3.6E-22 T 31-10-2018 IPR029052 Metallo-dependent phosphatase-like AF_1246 5e4dc16c96a156da9f73b9795c3cc79c 104 SUPERFAMILY SSF81324 6 73 2.62E-18 T 31-10-2018 AF_1246 5e4dc16c96a156da9f73b9795c3cc79c 104 Pfam PF07885 Ion channel 30 73 5.4E-12 T 31-10-2018 IPR013099 Potassium channel domain AF_1246 5e4dc16c96a156da9f73b9795c3cc79c 104 Gene3D G3DSA:1.10.287.70 1 81 1.9E-16 T 31-10-2018 AF_2231 f3296d4f5659f04104880ecc585e751f 328 Pfam PF03706 Lysylphosphatidylglycerol synthase TM region 1 309 6.4E-46 T 31-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AF_2231 f3296d4f5659f04104880ecc585e751f 328 TIGRFAM TIGR00374 TIGR00374: TIGR00374 family protein 4 325 2.5E-112 T 31-10-2018 IPR022791 Lysylphosphatidylglycerol synthetase/glycosyltransferase AglD AF_0319 cc8ccf43d6eb7bccb002b1e06c4ab42b 70 Gene3D G3DSA:4.10.1150.10 6 67 3.0E-20 T 31-10-2018 IPR024069 AF2212-like domain superfamily AF_0319 cc8ccf43d6eb7bccb002b1e06c4ab42b 70 Pfam PF01954 Protein of unknown function DUF104 6 61 1.5E-21 T 31-10-2018 IPR008203 Uncharacterised protein family UPF0165 AF_0319 cc8ccf43d6eb7bccb002b1e06c4ab42b 70 SUPERFAMILY SSF141694 6 60 4.45E-16 T 31-10-2018 AF_0926 a1c4ed133e7102aa564c3f4383da44f2 177 TIGRFAM TIGR00369 unchar_dom_1: uncharacterized domain 1 61 169 3.8E-22 T 31-10-2018 IPR003736 Phenylacetic acid degradation-related domain Reactome: R-HSA-77289 AF_0926 a1c4ed133e7102aa564c3f4383da44f2 177 Gene3D G3DSA:3.10.129.10 46 176 2.6E-31 T 31-10-2018 AF_0926 a1c4ed133e7102aa564c3f4383da44f2 177 SUPERFAMILY SSF54637 39 173 5.26E-27 T 31-10-2018 IPR029069 HotDog domain superfamily AF_0926 a1c4ed133e7102aa564c3f4383da44f2 177 Pfam PF03061 Thioesterase superfamily 85 162 3.2E-14 T 31-10-2018 IPR006683 Thioesterase domain Reactome: R-HSA-77289 AF_1754 75b911480cb0306fa4c8be45dd3616ae 100 Pfam PF05437 Branched-chain amino acid transport protein (AzlD) 6 97 3.0E-14 T 31-10-2018 IPR008407 Branched-chain amino acid transport, AzlD AF_1012 4f0bdce4a8c1a0f302460c0b3ac4b239 312 TIGRFAM TIGR01210 TIGR01210: radical SAM enzyme, TIGR01210 family 9 311 2.4E-144 T 31-10-2018 IPR005909 Conserved hypothetical protein CHP01210 AF_1012 4f0bdce4a8c1a0f302460c0b3ac4b239 312 PIRSF PIRSF004954 1 311 3.9E-132 T 31-10-2018 IPR005909 Conserved hypothetical protein CHP01210 AF_1012 4f0bdce4a8c1a0f302460c0b3ac4b239 312 SMART SM00729 23 239 3.9E-38 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AF_1012 4f0bdce4a8c1a0f302460c0b3ac4b239 312 SUPERFAMILY SSF102114 24 242 3.01E-18 T 31-10-2018 AF_1012 4f0bdce4a8c1a0f302460c0b3ac4b239 312 Pfam PF04055 Radical SAM superfamily 29 184 3.5E-10 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_0805 3dcc3dbc28a3dfbdd615a4de88ea0b3d 225 Pfam PF04967 HTH DNA binding domain 167 219 1.8E-21 T 31-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain AF_0939 80fe8c90bef0f31980ce8f24b5206e2f 306 Hamap MF_01818 Ribonuclease BN [rbn]. 3 301 39.142 T 31-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 AF_0939 80fe8c90bef0f31980ce8f24b5206e2f 306 Gene3D G3DSA:3.60.15.10 3 301 9.2E-98 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_0939 80fe8c90bef0f31980ce8f24b5206e2f 306 Pfam PF12706 Beta-lactamase superfamily domain 32 148 3.2E-12 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_0939 80fe8c90bef0f31980ce8f24b5206e2f 306 Pfam PF12706 Beta-lactamase superfamily domain 199 268 5.1E-9 T 31-10-2018 IPR001279 Metallo-beta-lactamase AF_0939 80fe8c90bef0f31980ce8f24b5206e2f 306 SUPERFAMILY SSF56281 4 301 1.26E-81 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_0939 80fe8c90bef0f31980ce8f24b5206e2f 306 TIGRFAM TIGR02651 RNase_Z: ribonuclease Z 4 301 2.5E-114 T 31-10-2018 IPR013471 Ribonuclease Z/BN GO:0016891|GO:0042779 AF_0288 2e927046f73efbf33013fa716896ad19 155 Pfam PF01583 Adenylylsulphate kinase 2 154 1.0E-63 T 31-10-2018 AF_0288 2e927046f73efbf33013fa716896ad19 155 TIGRFAM TIGR00455 apsK: adenylyl-sulfate kinase 2 154 8.9E-76 T 31-10-2018 IPR002891 Adenylyl-sulfate kinase GO:0000103|GO:0004020|GO:0005524 KEGG: 00230+2.7.1.25|KEGG: 00920+2.7.1.25|MetaCyc: PWY-5340|Reactome: R-HSA-174362|Reactome: R-HSA-2408550 AF_0288 2e927046f73efbf33013fa716896ad19 155 SUPERFAMILY SSF52540 3 153 1.3E-34 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0288 2e927046f73efbf33013fa716896ad19 155 Gene3D G3DSA:3.40.50.300 2 155 2.6E-57 T 31-10-2018 AF_1621 30bad72f04812a84b421147dd8b9a547 328 Pfam PF03601 Conserved hypothetical protein 698 22 307 6.5E-82 T 31-10-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 AF_1621 30bad72f04812a84b421147dd8b9a547 328 TIGRFAM TIGR00698 TIGR00698: conserved hypothetical protein 14 328 1.6E-142 T 31-10-2018 IPR004630 Uncharacterised protein family UPF0324, bacteria GO:0016021 AF_1493 603e735f31486569cd890647df5db914 67 SUPERFAMILY SSF47113 3 66 4.05E-19 T 31-10-2018 IPR009072 Histone-fold GO:0046982 AF_1493 603e735f31486569cd890647df5db914 67 Pfam PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone 2 65 5.3E-21 T 31-10-2018 IPR003958 Transcription factor CBF/NF-Y/archaeal histone domain AF_1493 603e735f31486569cd890647df5db914 67 Gene3D G3DSA:1.10.20.10 1 66 3.7E-22 T 31-10-2018 IPR009072 Histone-fold GO:0046982 AF_0078 5e9fd8505e78576ff69d12d568fb2485 246 SMART SM00460 167 227 2.6E-11 T 31-10-2018 IPR002931 Transglutaminase-like AF_0078 5e9fd8505e78576ff69d12d568fb2485 246 SUPERFAMILY SSF54001 121 218 1.32E-7 T 31-10-2018 IPR038765 Papain-like cysteine peptidase superfamily AF_0078 5e9fd8505e78576ff69d12d568fb2485 246 Pfam PF01841 Transglutaminase-like superfamily 156 214 3.5E-7 T 31-10-2018 IPR002931 Transglutaminase-like AF_1048 6d3aad92e7afae27ae38f2a7d62b1d6b 541 Pfam PF00482 Type II secretion system (T2SS), protein F 42 168 1.6E-8 T 31-10-2018 IPR018076 Type II secretion system F domain AF_1048 6d3aad92e7afae27ae38f2a7d62b1d6b 541 Pfam PF00482 Type II secretion system (T2SS), protein F 301 431 2.3E-9 T 31-10-2018 IPR018076 Type II secretion system F domain AF_0477 ea7378b9fa48c34d553bc595389866ed 409 Gene3D G3DSA:1.10.8.60 333 402 2.3E-14 T 31-10-2018 AF_0477 ea7378b9fa48c34d553bc595389866ed 409 SUPERFAMILY SSF52540 157 398 1.22E-51 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0477 ea7378b9fa48c34d553bc595389866ed 409 Gene3D G3DSA:3.40.50.300 150 331 4.5E-47 T 31-10-2018 AF_0477 ea7378b9fa48c34d553bc595389866ed 409 ProSitePatterns PS00674 AAA-protein family signature. 302 321 - T 31-10-2018 IPR003960 ATPase, AAA-type, conserved site GO:0005524 AF_0477 ea7378b9fa48c34d553bc595389866ed 409 SMART SM00382 197 332 4.3E-15 T 31-10-2018 IPR003593 AAA+ ATPase domain AF_0477 ea7378b9fa48c34d553bc595389866ed 409 Pfam PF00004 ATPase family associated with various cellular activities (AAA) 201 329 1.8E-37 T 31-10-2018 IPR003959 ATPase, AAA-type, core GO:0005524 AF_0332 ead814e495cc76ae2792a0d9f517d06d 362 PIRSF PIRSF006404 1 354 1.6E-125 T 31-10-2018 IPR016483 Uncharacterised conserved protein UCP006404, peptidase M50/CBS AF_0332 ead814e495cc76ae2792a0d9f517d06d 362 Gene3D G3DSA:3.10.580.10 195 287 1.1E-14 T 31-10-2018 AF_0332 ead814e495cc76ae2792a0d9f517d06d 362 Pfam PF00571 CBS domain 234 286 1.7E-14 T 31-10-2018 IPR000644 CBS domain AF_0332 ead814e495cc76ae2792a0d9f517d06d 362 Pfam PF00571 CBS domain 292 343 3.6E-15 T 31-10-2018 IPR000644 CBS domain AF_0332 ead814e495cc76ae2792a0d9f517d06d 362 SMART SM00116 299 346 2.3E-13 T 31-10-2018 IPR000644 CBS domain AF_0332 ead814e495cc76ae2792a0d9f517d06d 362 SMART SM00116 241 288 9.1E-13 T 31-10-2018 IPR000644 CBS domain AF_0332 ead814e495cc76ae2792a0d9f517d06d 362 Gene3D G3DSA:3.10.580.10 288 346 3.9E-17 T 31-10-2018 AF_0332 ead814e495cc76ae2792a0d9f517d06d 362 SUPERFAMILY SSF54631 228 343 1.52E-36 T 31-10-2018 AF_0332 ead814e495cc76ae2792a0d9f517d06d 362 Pfam PF02163 Peptidase family M50 134 193 1.4E-9 T 31-10-2018 IPR008915 Peptidase M50 GO:0004222|GO:0006508 Reactome: R-HSA-1655829|Reactome: R-HSA-381033|Reactome: R-HSA-8874211|Reactome: R-HSA-8963889 AF_1878 8d675813d15abe5980c9ab603e9922d7 345 Gene3D G3DSA:3.100.10.20 1 80 7.1E-26 T 31-10-2018 AF_1878 8d675813d15abe5980c9ab603e9922d7 345 Pfam PF01867 CRISPR associated protein Cas1 3 299 9.0E-85 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 AF_1878 8d675813d15abe5980c9ab603e9922d7 345 Hamap MF_01470 CRISPR-associated endonuclease Cas1 [cas1]. 1 330 27.504 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 AF_1878 8d675813d15abe5980c9ab603e9922d7 345 TIGRFAM TIGR00287 cas1: CRISPR-associated endonuclease Cas1 3 339 1.0E-108 T 31-10-2018 IPR002729 CRISPR-associated protein Cas1 GO:0003676|GO:0004519|GO:0043571|GO:0046872|GO:0051607 AF_1878 8d675813d15abe5980c9ab603e9922d7 345 Gene3D G3DSA:1.20.120.920 81 345 4.2E-86 T 31-10-2018 AF_1307 f539adc3c6f23d4de3b30fd4913e2c22 264 Pfam PF02593 Domain of unknown function 5 245 8.3E-70 T 31-10-2018 IPR003745 Protein of unknown function DUF166 AF_1090 f97c3032a7aa64436f527695d6f095e6 59 Pfam PF01954 Protein of unknown function DUF104 1 55 8.7E-21 T 31-10-2018 IPR008203 Uncharacterised protein family UPF0165 AF_1090 f97c3032a7aa64436f527695d6f095e6 59 Gene3D G3DSA:4.10.1150.10 1 58 1.2E-18 T 31-10-2018 IPR024069 AF2212-like domain superfamily AF_1090 f97c3032a7aa64436f527695d6f095e6 59 SUPERFAMILY SSF141694 1 57 4.18E-16 T 31-10-2018 AF_0582 6ea9805ffb8c734c61947b3986aa71ff 440 Pfam PF10060 Uncharacterized membrane protein (DUF2298) 57 438 8.2E-64 T 31-10-2018 IPR018746 Protein of unknown function DUF2298 AF_1043 caf694760d378b8948a35f0671e3d064 269 PIRSF PIRSF026802 1 267 2.4E-122 T 31-10-2018 IPR007381 Chemotaxis signal transduction system protein F AF_1043 caf694760d378b8948a35f0671e3d064 269 Pfam PF04283 Chemotaxis signal transduction system protein F from archaea 19 187 8.3E-19 T 31-10-2018 IPR007381 Chemotaxis signal transduction system protein F AF_2041 6ff4495d401f7d959792e20706bae214 162 Pfam PF14329 Domain of unknown function (DUF4386) 16 69 5.2E-8 T 31-10-2018 IPR025495 Protein of unknown function DUF4386 AF_2041 6ff4495d401f7d959792e20706bae214 162 Pfam PF14329 Domain of unknown function (DUF4386) 66 152 1.1E-16 T 31-10-2018 IPR025495 Protein of unknown function DUF4386 AF_1641 341cbb0a412df76b24f7e237254aa91a 254 SUPERFAMILY SSF52096 3 254 2.2E-77 T 31-10-2018 IPR029045 ClpP/crotonase-like domain superfamily AF_1641 341cbb0a412df76b24f7e237254aa91a 254 Gene3D G3DSA:3.90.226.10 3 197 1.5E-63 T 31-10-2018 AF_1641 341cbb0a412df76b24f7e237254aa91a 254 Gene3D G3DSA:1.10.12.10 200 254 1.1E-13 T 31-10-2018 IPR014748 Enoyl-CoA hydratase, C-terminal AF_1641 341cbb0a412df76b24f7e237254aa91a 254 Pfam PF00378 Enoyl-CoA hydratase/isomerase 10 254 1.5E-56 T 31-10-2018 IPR001753 Enoyl-CoA hydratase/isomerase GO:0003824 AF_2330 5dff31d1c92db338f07a94200ca28085 129 SUPERFAMILY SSF52980 2 94 2.15E-12 T 31-10-2018 IPR011335 Restriction endonuclease type II-like Reactome: R-HSA-6783310 AF_0037 d3543fb4e08285381ca130ddc584d3f1 265 Pfam PF02654 Cobalamin-5-phosphate synthase 50 256 2.6E-35 T 31-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 AF_0037 d3543fb4e08285381ca130ddc584d3f1 265 TIGRFAM TIGR00317 cobS: cobalamin 5'-phosphate synthase 43 260 2.7E-78 T 31-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 AF_0037 d3543fb4e08285381ca130ddc584d3f1 265 Hamap MF_00719 Adenosylcobinamide-GDP ribazoletransferase [cobS]. 1 265 19.803 T 31-10-2018 IPR003805 Adenosylcobinamide-GDP ribazoletransferase GO:0008818|GO:0009236|GO:0051073 KEGG: 00860+2.7.8.26|MetaCyc: PWY-5509|MetaCyc: PWY-6269|MetaCyc: PWY-7961|MetaCyc: PWY-7963|MetaCyc: PWY-7964|MetaCyc: PWY-7965|MetaCyc: PWY-7966|MetaCyc: PWY-7967|MetaCyc: PWY-7968|MetaCyc: PWY-7969|MetaCyc: PWY-7970|MetaCyc: PWY-7975 AF_1105 d075f6a8664fda006d4a08f5dbb2779a 191 Pfam PF04071 Cysteine-rich small domain 24 89 5.6E-21 T 31-10-2018 IPR007212 Cysteine-rich small domain AF_1002 9728da182df53b419cd40e50edb1d2c1 151 TIGRFAM TIGR00249 sixA: phosphohistidine phosphatase SixA 1 147 1.4E-61 T 31-10-2018 IPR004449 Phosphohistidine phosphatase SixA GO:0005737|GO:0006464|GO:0101006 AF_1002 9728da182df53b419cd40e50edb1d2c1 151 Gene3D G3DSA:3.40.50.1240 1 151 3.4E-33 T 31-10-2018 IPR029033 Histidine phosphatase superfamily AF_1002 9728da182df53b419cd40e50edb1d2c1 151 SUPERFAMILY SSF53254 1 139 5.57E-22 T 31-10-2018 IPR029033 Histidine phosphatase superfamily AF_1002 9728da182df53b419cd40e50edb1d2c1 151 Pfam PF00300 Histidine phosphatase superfamily (branch 1) 3 77 1.8E-10 T 31-10-2018 IPR013078 Histidine phosphatase superfamily, clade-1 AF_1920 395fe1d43a05b5cfa5212b44e30f44c9 155 Pfam PF00237 Ribosomal protein L22p/L17e 21 151 1.4E-32 T 31-10-2018 IPR001063 Ribosomal protein L22/L17 GO:0003735|GO:0005840|GO:0006412 AF_1920 395fe1d43a05b5cfa5212b44e30f44c9 155 TIGRFAM TIGR01038 uL22_arch_euk: ribosomal protein uL22 8 154 1.7E-71 T 31-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1920 395fe1d43a05b5cfa5212b44e30f44c9 155 Hamap MF_01331_A 50S ribosomal protein L22 [rplV]. 4 155 35.479 T 31-10-2018 IPR005721 Ribosomal protein L22/L17, eukaryotic/archaeal GO:0003735|GO:0006412|GO:0015934 Reactome: R-HSA-156827|Reactome: R-HSA-156902|Reactome: R-HSA-1799339|Reactome: R-HSA-192823|Reactome: R-HSA-2408557|Reactome: R-HSA-6791226|Reactome: R-HSA-72689|Reactome: R-HSA-72706|Reactome: R-HSA-72764|Reactome: R-HSA-9010553|Reactome: R-HSA-975956|Reactome: R-HSA-975957 AF_1920 395fe1d43a05b5cfa5212b44e30f44c9 155 SUPERFAMILY SSF54843 6 152 2.35E-49 T 31-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 AF_1920 395fe1d43a05b5cfa5212b44e30f44c9 155 Gene3D G3DSA:3.90.470.10 5 155 1.2E-54 T 31-10-2018 IPR036394 Ribosomal protein L22/L17 superfamily GO:0003735|GO:0005840|GO:0006412 AF_1843 8f54d6be99bd8aee8dce086b274cd590 273 Pfam PF13190 PDGLE domain 162 266 2.5E-8 T 31-10-2018 IPR025937 PDGLE domain AF_1843 8f54d6be99bd8aee8dce086b274cd590 273 Pfam PF01891 Cobalt uptake substrate-specific transmembrane region 2 176 2.0E-56 T 31-10-2018 IPR002751 Metal transport protein CbiM/NikMN GO:0000041|GO:0016021 AF_1843 8f54d6be99bd8aee8dce086b274cd590 273 Gene3D G3DSA:1.10.1760.20 1 176 5.9E-58 T 31-10-2018 AF_0322 d46f18ff3ca500c38b320b789ec05d46 286 SUPERFAMILY SSF53448 4 233 8.0E-50 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0322 d46f18ff3ca500c38b320b789ec05d46 286 Pfam PF00535 Glycosyl transferase family 2 6 173 3.4E-26 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AF_0322 d46f18ff3ca500c38b320b789ec05d46 286 Gene3D G3DSA:3.90.550.10 1 217 4.8E-43 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0784 08488c3d3b0517dd966688170c3b6bda 81 Pfam PF02416 mttA/Hcf106 family 2 47 2.1E-8 T 31-10-2018 IPR003369 Sec-independent protein translocase protein TatA/B/E GO:0008565|GO:0015031 AF_2311 33be250f5b8c27dbfbac9198b02b93d2 49 SUPERFAMILY SSF46785 1 47 5.54E-12 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_2311 33be250f5b8c27dbfbac9198b02b93d2 49 Pfam PF12802 MarR family 5 37 8.7E-7 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AF_2311 33be250f5b8c27dbfbac9198b02b93d2 49 Gene3D G3DSA:1.10.10.10 1 47 7.4E-12 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1250 399fcb73a679881fb4040569ca8f01e4 129 ProDom PD020987 PF0014 UNCHARACTERIZED AF1250 PH0127 MJ0105 MA4414 ARCHAEAL 1 107 1.0E-56 T 31-10-2018 IPR007417 Protein of unknown function DUF473 AF_1250 399fcb73a679881fb4040569ca8f01e4 129 Pfam PF04322 Protein of unknown function (DUF473) 1 116 3.5E-42 T 31-10-2018 IPR007417 Protein of unknown function DUF473 AF_0601 a9fc001da3929cef365e02782f7fad81 344 Gene3D G3DSA:3.40.50.150 153 334 1.4E-29 T 31-10-2018 AF_0601 a9fc001da3929cef365e02782f7fad81 344 Pfam PF05050 Methyltransferase FkbM domain 172 318 3.2E-16 T 31-10-2018 IPR006342 Methyltransferase FkbM AF_0601 a9fc001da3929cef365e02782f7fad81 344 TIGRFAM TIGR01444 fkbM_fam: methyltransferase, FkbM family 169 307 1.0E-36 T 31-10-2018 IPR006342 Methyltransferase FkbM AF_0601 a9fc001da3929cef365e02782f7fad81 344 SUPERFAMILY SSF53335 87 331 1.79E-43 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_1505 d637bff44853458e81ba4d85c4b1d031 336 SUPERFAMILY SSF161093 165 335 1.29E-26 T 31-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 AF_1505 d637bff44853458e81ba4d85c4b1d031 336 SUPERFAMILY SSF161093 2 133 9.68E-22 T 31-10-2018 IPR036739 SLC41 divalent cation transporters, integral membrane domain superfamily GO:0006812|GO:0008324 AF_1505 d637bff44853458e81ba4d85c4b1d031 336 Pfam PF01769 Divalent cation transporter 2 126 3.4E-20 T 31-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 AF_1505 d637bff44853458e81ba4d85c4b1d031 336 Pfam PF01769 Divalent cation transporter 206 329 2.5E-18 T 31-10-2018 IPR006667 SLC41 divalent cation transporters, integral membrane domain GO:0006812|GO:0008324 AF_1505 d637bff44853458e81ba4d85c4b1d031 336 Gene3D G3DSA:1.10.357.20 164 336 2.1E-15 T 31-10-2018 IPR038048 Magnesium transporter MgtE, transmembrane domain AF_0213 f79f009137bb839e71472206996222bd 259 SUPERFAMILY SSF46785 21 112 2.77E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0213 f79f009137bb839e71472206996222bd 259 Gene3D G3DSA:1.10.10.10 22 120 1.5E-27 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0213 f79f009137bb839e71472206996222bd 259 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 30 97 3.9E-26 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal AF_0830 10b24df2c1b764c61bd26803ad01717d 169 SUPERFAMILY SSF50475 4 157 2.01E-35 T 31-10-2018 AF_0830 10b24df2c1b764c61bd26803ad01717d 169 Pfam PF01613 Flavin reductase like domain 8 151 8.7E-23 T 31-10-2018 IPR002563 Flavin reductase like domain GO:0010181 AF_0830 10b24df2c1b764c61bd26803ad01717d 169 SMART SM00903 6 152 4.6E-23 T 31-10-2018 IPR002563 Flavin reductase like domain GO:0010181 AF_0830 10b24df2c1b764c61bd26803ad01717d 169 Gene3D G3DSA:2.30.110.10 1 169 1.5E-43 T 31-10-2018 IPR012349 FMN-binding split barrel GO:0048037 AF_0974 c357a4087bdb268adf0132f901bc15ae 450 Gene3D G3DSA:3.30.1540.10 277 376 7.4E-92 T 31-10-2018 AF_0974 c357a4087bdb268adf0132f901bc15ae 450 Pfam PF02515 CoA-transferase family III 36 426 2.5E-118 T 31-10-2018 IPR003673 CoA-transferase family III GO:0003824 AF_0974 c357a4087bdb268adf0132f901bc15ae 450 Gene3D G3DSA:3.40.50.10540 37 444 7.4E-92 T 31-10-2018 IPR023606 CoA-transferase family III domain superfamily AF_0974 c357a4087bdb268adf0132f901bc15ae 450 SUPERFAMILY SSF89796 34 450 1.44E-91 T 31-10-2018 IPR023606 CoA-transferase family III domain superfamily AF_1681 ba0587c6eaa0e6962d8755d297296013 212 Pfam PF17278 Family of unknown function (DUF5343) 16 152 4.0E-53 T 31-10-2018 IPR035235 Protein of unknown function DUF5343 AF_1681 ba0587c6eaa0e6962d8755d297296013 212 ProDom PD111187 AF1681 16 212 5.0E-113 T 31-10-2018 IPR035235 Protein of unknown function DUF5343 AF_1311 06207e7d55d19d3a15b7327b11e18164 287 Gene3D G3DSA:3.20.20.70 13 239 1.0E-21 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1311 06207e7d55d19d3a15b7327b11e18164 287 SUPERFAMILY SSF102114 3 239 1.57E-42 T 31-10-2018 AF_1311 06207e7d55d19d3a15b7327b11e18164 287 Pfam PF04055 Radical SAM superfamily 21 174 2.5E-17 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_1311 06207e7d55d19d3a15b7327b11e18164 287 SMART SM00729 15 232 4.7E-35 T 31-10-2018 IPR006638 Elp3/MiaB/NifB GO:0003824|GO:0051536 AF_0787 46e4a809dd40fd8aa0c8705e68b385aa 358 Pfam PF07854 Protein of unknown function (DUF1646) 15 358 4.6E-162 T 31-10-2018 IPR012443 Protein of unknown function DUF1646 AF_0787 46e4a809dd40fd8aa0c8705e68b385aa 358 PIRSF PIRSF019205 8 358 8.6E-159 T 31-10-2018 IPR012443 Protein of unknown function DUF1646 AF_0195 65e993e219b1aea782dc4e30cd812b9f 106 SUPERFAMILY SSF47240 2 98 2.88E-6 T 31-10-2018 IPR009078 Ferritin-like superfamily AF_0621 c241c3e15f30208eb76015fb0c6db2a7 205 Gene3D G3DSA:3.30.420.10 1 155 1.1E-61 T 31-10-2018 IPR036397 Ribonuclease H superfamily GO:0003676 AF_0621 c241c3e15f30208eb76015fb0c6db2a7 205 SUPERFAMILY SSF53098 2 198 3.19E-51 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily AF_0621 c241c3e15f30208eb76015fb0c6db2a7 205 Pfam PF01351 Ribonuclease HII 3 194 8.5E-63 T 31-10-2018 IPR024567 Ribonuclease HII/HIII domain AF_0621 c241c3e15f30208eb76015fb0c6db2a7 205 TIGRFAM TIGR00729 TIGR00729: ribonuclease HII 3 199 3.6E-81 T 31-10-2018 IPR004649 Ribonuclease H2, subunit A GO:0004523|GO:0016070 AF_0621 c241c3e15f30208eb76015fb0c6db2a7 205 Hamap MF_00052_A Ribonuclease HII [rnhB]. 1 199 34.193 T 31-10-2018 IPR020787 Ribonuclease HII, archaea GO:0004523|GO:0005737|GO:0006401|GO:0030145 AF_0621 c241c3e15f30208eb76015fb0c6db2a7 205 Gene3D G3DSA:1.10.10.460 156 205 6.9E-25 T 31-10-2018 IPR023160 Ribonuclease HII, helix-loop-helix cap domain superfamily GO:0004523 AF_0737 b2ca8b3878e58d81dd384278d7ba81a4 67 Gene3D G3DSA:3.10.20.630 1 67 2.1E-23 T 31-10-2018 AF_0737 b2ca8b3878e58d81dd384278d7ba81a4 67 SUPERFAMILY SSF54285 10 67 1.98E-7 T 31-10-2018 IPR016155 Molybdopterin synthase/thiamin biosynthesis sulphur carrier, beta-grasp AF_1795 15b58991121acac2c423458dc5bff885 304 Gene3D G3DSA:2.40.30.40 24 115 3.5E-116 T 31-10-2018 IPR023367 Peptidase M42, domain 2 AF_1795 15b58991121acac2c423458dc5bff885 304 Pfam PF05343 M42 glutamyl aminopeptidase 2 291 6.1E-111 T 31-10-2018 IPR008007 Peptidase M42 AF_1795 15b58991121acac2c423458dc5bff885 304 SUPERFAMILY SSF101821 25 132 7.63E-33 T 31-10-2018 AF_1795 15b58991121acac2c423458dc5bff885 304 Gene3D G3DSA:3.40.630.10 1 292 3.5E-116 T 31-10-2018 AF_1795 15b58991121acac2c423458dc5bff885 304 SUPERFAMILY SSF53187 19 302 6.56E-56 T 31-10-2018 AF_0462 732be9dba954ff01b5728967fa354c1c 276 Pfam PF01889 Membrane protein of unknown function DUF63 16 275 2.5E-94 T 31-10-2018 IPR002749 Protein of unknown function DUF63 AF_0824 4086a0ff32a502308ffac9a260be8efd 323 Pfam PF02653 Branched-chain amino acid transport system / permease component 26 291 2.6E-49 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AF_0361 c627d6956f9f3f6b8f000cd5eeb847a0 305 SUPERFAMILY SSF51735 2 299 6.67E-82 T 31-10-2018 IPR036291 NAD(P)-binding domain superfamily AF_0361 c627d6956f9f3f6b8f000cd5eeb847a0 305 Pfam PF01370 NAD dependent epimerase/dehydratase family 2 228 4.0E-51 T 31-10-2018 IPR001509 NAD-dependent epimerase/dehydratase GO:0003824|GO:0050662 AF_0361 c627d6956f9f3f6b8f000cd5eeb847a0 305 Gene3D G3DSA:3.90.25.10 168 288 6.7E-115 T 31-10-2018 AF_0361 c627d6956f9f3f6b8f000cd5eeb847a0 305 Gene3D G3DSA:3.40.50.720 2 228 6.7E-115 T 31-10-2018 AF_1536 5c6e064133237363ca73a278fc9fe876 82 SUPERFAMILY SSF52833 1 73 1.86E-17 T 31-10-2018 IPR036249 Thioredoxin-like superfamily AF_1536 5c6e064133237363ca73a278fc9fe876 82 Pfam PF00462 Glutaredoxin 4 68 7.6E-15 T 31-10-2018 IPR002109 Glutaredoxin GO:0009055|GO:0015035|GO:0045454 AF_1536 5c6e064133237363ca73a278fc9fe876 82 ProSitePatterns PS00195 Glutaredoxin active site. 6 22 - T 31-10-2018 IPR011767 Glutaredoxin active site GO:0009055|GO:0045454 Reactome: R-HSA-499943 AF_1536 5c6e064133237363ca73a278fc9fe876 82 Gene3D G3DSA:3.40.30.10 1 82 4.2E-26 T 31-10-2018 AF_1189 98de305fb9a5955366b476482ee8e319 63 SMART SM00355 2 25 0.005 T 31-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 AF_1189 98de305fb9a5955366b476482ee8e319 63 Gene3D G3DSA:3.30.160.60 2 27 6.0E-7 T 31-10-2018 AF_1189 98de305fb9a5955366b476482ee8e319 63 ProSitePatterns PS00028 Zinc finger C2H2 type domain signature. 4 25 - T 31-10-2018 IPR013087 Zinc finger C2H2-type GO:0003676 AF_1189 98de305fb9a5955366b476482ee8e319 63 SUPERFAMILY SSF57667 3 27 9.75E-5 T 31-10-2018 IPR036236 Zinc finger C2H2 superfamily AF_1189 98de305fb9a5955366b476482ee8e319 63 Pfam PF13894 C2H2-type zinc finger 3 25 9.0E-7 T 31-10-2018 AF_2333 2d6c513213f1f89c1a479e7ae2c23ceb 380 Pfam PF04412 Protein of unknown function (DUF521) 9 376 6.1E-140 T 31-10-2018 IPR007506 Aconitase X catalytic domain, putative AF_0934 3d937c73badc3dbbd2779ccd4dc43860 171 Gene3D G3DSA:3.30.70.260 5 81 2.4E-5 T 31-10-2018 AF_0934 3d937c73badc3dbbd2779ccd4dc43860 171 Pfam PF01842 ACT domain 7 72 2.6E-8 T 31-10-2018 IPR002912 ACT domain AF_0934 3d937c73badc3dbbd2779ccd4dc43860 171 SUPERFAMILY SSF55021 7 77 1.34E-8 T 31-10-2018 AF_1773 ba994f461d2f86e7eb60349fd368ff4b 384 SUPERFAMILY SSF46548 20 96 2.44E-14 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_1773 ba994f461d2f86e7eb60349fd368ff4b 384 Gene3D G3DSA:1.10.1060.10 5 100 9.9E-7 T 31-10-2018 IPR009051 Alpha-helical ferredoxin GO:0051536 AF_1773 ba994f461d2f86e7eb60349fd368ff4b 384 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 23 34 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1773 ba994f461d2f86e7eb60349fd368ff4b 384 Pfam PF02754 Cysteine-rich domain 148 233 6.9E-17 T 31-10-2018 IPR004017 Cysteine-rich domain AF_1773 ba994f461d2f86e7eb60349fd368ff4b 384 Pfam PF02754 Cysteine-rich domain 267 354 5.4E-17 T 31-10-2018 IPR004017 Cysteine-rich domain AF_1773 ba994f461d2f86e7eb60349fd368ff4b 384 ProSitePatterns PS00198 4Fe-4S ferredoxin-type iron-sulfur binding region signature. 67 78 - T 31-10-2018 IPR017900 4Fe-4S ferredoxin, iron-sulphur binding, conserved site AF_1773 ba994f461d2f86e7eb60349fd368ff4b 384 Pfam PF13534 4Fe-4S dicluster domain 22 81 1.7E-7 T 31-10-2018 AF_1966 3eb42f54d9862d0721937e722b9e3f2e 191 PIRSF PIRSF015877 1 191 6.1E-66 T 31-10-2018 IPR012041 Uncharacterised conserved protein UCP015877, zinc finger-containing AF_0049 f27375ac84e7db1b48574114716cd2d2 412 Pfam PF09861 Domain of unknown function (DUF2088) 10 201 2.3E-59 T 31-10-2018 IPR018657 LarA-like, N-terminal GO:0050043 KEGG: 00620+5.1.2.1 AF_0049 f27375ac84e7db1b48574114716cd2d2 412 Gene3D G3DSA:3.40.50.11440 38 279 8.1E-72 T 31-10-2018 AF_1479 8002143a55b41c07e189414f2b46661c 130 Gene3D G3DSA:3.40.50.1010 1 129 1.2E-28 T 31-10-2018 AF_1479 8002143a55b41c07e189414f2b46661c 130 SUPERFAMILY SSF88723 1 126 7.57E-30 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_1479 8002143a55b41c07e189414f2b46661c 130 Pfam PF01850 PIN domain 3 121 1.6E-19 T 31-10-2018 IPR002716 PIN domain AF_2302 127fc29c4538f5bb54953f7bf320cd24 208 Pfam PF14401 RimK-like ATPgrasp N-terminal domain 17 177 3.4E-17 T 31-10-2018 IPR025839 RimK-like ATPgrasp N-terminal domain AF_1735 684ac151e4427221156e555df02266cf 319 Pfam PF12698 ABC-2 family transporter protein 9 273 4.7E-13 T 31-10-2018 AF_0019 cbbbacf3c6c9d4f0b09355bca4e0b7a8 160 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 39 72 1.5E-12 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AF_0019 cbbbacf3c6c9d4f0b09355bca4e0b7a8 160 SUPERFAMILY SSF50249 29 145 7.54E-28 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0019 cbbbacf3c6c9d4f0b09355bca4e0b7a8 160 Gene3D G3DSA:1.10.12.20 26 76 4.7E-11 T 31-10-2018 AF_0019 cbbbacf3c6c9d4f0b09355bca4e0b7a8 160 Pfam PF01796 DUF35 OB-fold domain, acyl-CoA-associated 73 138 6.7E-7 T 31-10-2018 IPR002878 Domain of unknown function DUF35, OB-fold, C-terminal AF_2198 b837e0fcb76600add4b0fdd812bd1ff4 121 Pfam PF14464 Prokaryotic homologs of the JAB domain 7 105 2.5E-11 T 31-10-2018 IPR028090 JAB domain, prokaryotic AF_2198 b837e0fcb76600add4b0fdd812bd1ff4 121 Gene3D G3DSA:3.40.140.10 1 121 4.2E-36 T 31-10-2018 AF_2198 b837e0fcb76600add4b0fdd812bd1ff4 121 SUPERFAMILY SSF102712 1 117 9.68E-32 T 31-10-2018 AF_2058 b273cafa5babc903e43304ed3994b2b1 344 Pfam PF04123 Domain of unknown function (DUF373) 4 334 3.8E-119 T 31-10-2018 IPR007254 Protein of unknown function DUF373 AF_1183 ac86e41abccc5d68ff2cd4ffecc34330 107 Pfam PF09845 Zn-ribbon containing protein 48 101 6.2E-15 T 31-10-2018 IPR018645 Zn-ribbon containing protein AF_1936 fae74847bc71a1d76ac784663fbee181 227 TIGRFAM TIGR03875 RNA_lig_partner: RNA ligase partner, MJ_0950 family 4 210 1.7E-88 T 31-10-2018 IPR014856 PIN-domain ribonuclease AF_1936 fae74847bc71a1d76ac784663fbee181 227 Pfam PF08745 PINc domain ribonuclease 4 211 2.2E-90 T 31-10-2018 IPR014856 PIN-domain ribonuclease AF_1936 fae74847bc71a1d76ac784663fbee181 227 Hamap MF_01078 UPF0278 protein . 2 213 37.835 T 31-10-2018 IPR014856 PIN-domain ribonuclease AF_0187 f49de678479b2c842e4f69538378d3eb 119 Pfam PF02635 DsrE/DsrF-like family 3 119 2.0E-19 T 31-10-2018 IPR003787 Sulphur relay, DsrE/F-like protein AF_0187 f49de678479b2c842e4f69538378d3eb 119 Gene3D G3DSA:3.40.1260.10 1 119 5.7E-36 T 31-10-2018 IPR027396 DsrEFH-like AF_0187 f49de678479b2c842e4f69538378d3eb 119 SUPERFAMILY SSF75169 1 119 4.71E-25 T 31-10-2018 IPR027396 DsrEFH-like AF_0191 c6a9d794a9df90576a6c7fd4da7ecff6 86 Gene3D G3DSA:3.40.50.1000 1 49 2.3E-6 T 31-10-2018 IPR023214 HAD superfamily AF_0191 c6a9d794a9df90576a6c7fd4da7ecff6 86 SUPERFAMILY SSF56784 5 82 1.76E-13 T 31-10-2018 IPR036412 HAD-like superfamily AF_1199 621aeba00159719fbd76e030092fcc04 447 Gene3D G3DSA:3.30.30.40 262 297 5.7E-90 T 31-10-2018 AF_1199 621aeba00159719fbd76e030092fcc04 447 SUPERFAMILY SSF100950 146 427 1.14E-77 T 31-10-2018 IPR037171 NagB/RpiA transferase-like AF_1199 621aeba00159719fbd76e030092fcc04 447 SMART SM00882 148 369 1.2E-39 T 31-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 AF_1199 621aeba00159719fbd76e030092fcc04 447 Pfam PF01144 Coenzyme A transferase 148 368 1.5E-53 T 31-10-2018 IPR004165 Coenzyme A transferase family I GO:0008410 Reactome: R-HSA-77108 AF_1199 621aeba00159719fbd76e030092fcc04 447 Gene3D G3DSA:3.40.1080.10 149 430 5.7E-90 T 31-10-2018 AF_0365 8df0e96d55f276cc9b5f55fe3c972c74 175 Pfam PF01402 Ribbon-helix-helix protein, copG family 4 39 8.6E-11 T 31-10-2018 IPR002145 Ribbon-helix-helix protein, CopG GO:0006355 AF_1056 faead0a4e1e17909bd4ea83622dbddff 288 Hamap MF_00587 tRNA (pseudouridine(54)-N(1))-methyltransferase [trmY]. 95 287 38.895 T 31-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 AF_1056 faead0a4e1e17909bd4ea83622dbddff 288 Pfam PF04013 Putative SAM-dependent RNA methyltransferase 95 288 3.2E-87 T 31-10-2018 IPR007158 tRNA (pseudouridine(54)-N(1))-methyltransferase, TrmY GO:0008175 AF_1056 faead0a4e1e17909bd4ea83622dbddff 288 SUPERFAMILY SSF75217 96 286 1.53E-64 T 31-10-2018 IPR029028 Alpha/beta knot methyltransferases AF_1056 faead0a4e1e17909bd4ea83622dbddff 288 Gene3D G3DSA:3.40.1280.10 93 288 9.9E-85 T 31-10-2018 IPR029026 tRNA (guanine-N1-)-methyltransferase, N-terminal AF_2038 c20cc66c991837e080f6c240517b1c3c 627 Pfam PF05670 Domain of unknown function (DUF814) 427 526 1.1E-25 T 31-10-2018 IPR008532 Domain of unknown function DUF814 AF_2038 c20cc66c991837e080f6c240517b1c3c 627 Gene3D G3DSA:2.30.310.10 4 146 1.4E-30 T 31-10-2018 AF_2038 c20cc66c991837e080f6c240517b1c3c 627 Pfam PF05833 Fibronectin-binding protein A N-terminus (FbpA) 6 407 5.3E-77 T 31-10-2018 AF_2038 c20cc66c991837e080f6c240517b1c3c 627 SUPERFAMILY SSF46946 163 204 1.44E-7 T 31-10-2018 IPR010979 Ribosomal protein S13-like, H2TH GO:0003676 AF_1456 770081ad8798dc7ce995e82fb821308b 57 ProDom PD052018 AF1456 COIL COILED 2 57 1.0E-11 T 31-10-2018 AF_1501 2202fb7c8833a2273a8e98729a1f3054 247 Pfam PF09987 Uncharacterized protein conserved in archaea (DUF2226) 121 240 2.8E-38 T 31-10-2018 IPR019249 Protein of unknown function DUF2226 AF_1501 2202fb7c8833a2273a8e98729a1f3054 247 Pfam PF09987 Uncharacterized protein conserved in archaea (DUF2226) 1 120 6.3E-41 T 31-10-2018 IPR019249 Protein of unknown function DUF2226 AF_1800 7d19346492ca628e9e0b63e8186cdd53 340 Pfam PF01594 AI-2E family transporter 9 325 2.7E-69 T 31-10-2018 IPR002549 Transmembrane protein TqsA-like AF_1628 90266ec35d608ba4f2545c7dca53d208 344 Pfam PF01609 Transposase DDE domain 120 320 1.4E-24 T 31-10-2018 IPR002559 Transposase, IS4-like GO:0003677|GO:0004803|GO:0006313 AF_0224 5b631ff4ab5e8b473a08b0e345afef47 284 Pfam PF02653 Branched-chain amino acid transport system / permease component 10 272 9.1E-45 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AF_2126 12d9d7ba7df14d0351d317de10f6ba8f 298 Pfam PF02596 Uncharacterised ArCR, COG2043 49 255 8.0E-50 T 31-10-2018 IPR003748 Protein of unknown function DUF169 AF_2387 e3ca67018f93a955bc1067e123db9591 144 Pfam PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family 59 116 3.6E-7 T 31-10-2018 IPR007269 Isoprenylcysteine carboxyl methyltransferase GO:0004671|GO:0006481|GO:0016021 Reactome: R-HSA-163841 AF_2387 e3ca67018f93a955bc1067e123db9591 144 Gene3D G3DSA:1.20.120.1630 2 136 1.5E-19 T 31-10-2018 AF_0363 e079993f0d32bc43da9709133f8c8955 128 Pfam PF01047 MarR family 6 55 1.2E-10 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AF_0363 e079993f0d32bc43da9709133f8c8955 128 SUPERFAMILY SSF46785 3 78 1.01E-13 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_0363 e079993f0d32bc43da9709133f8c8955 128 Gene3D G3DSA:1.10.10.10 1 95 4.0E-10 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_0363 e079993f0d32bc43da9709133f8c8955 128 SMART SM00347 1 96 0.0036 T 31-10-2018 IPR000835 MarR-type HTH domain GO:0003700|GO:0006355 AF_0331 4daca1e1a6f25458e1adca1ea3ef96b2 396 TIGRFAM TIGR00261 traB: TraB family protein 1 377 1.3E-197 T 31-10-2018 IPR005230 Pheromone shutdown, TraB, bacterial/archaeal AF_0331 4daca1e1a6f25458e1adca1ea3ef96b2 396 Pfam PF01963 TraB family 5 220 1.9E-31 T 31-10-2018 IPR002816 Pheromone shutdown, TraB AF_0655 de7935129a8e9bf26bb7f45b11dff155 425 SUPERFAMILY SSF111283 3 419 2.49E-92 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 AF_0655 de7935129a8e9bf26bb7f45b11dff155 425 Pfam PF01523 Putative modulator of DNA gyrase 3 283 3.3E-53 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 AF_0655 de7935129a8e9bf26bb7f45b11dff155 425 Gene3D G3DSA:3.30.2290.10 4 121 5.0E-6 T 31-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal AF_0655 de7935129a8e9bf26bb7f45b11dff155 425 PIRSF PIRSF004919 1 425 1.2E-148 T 31-10-2018 IPR025502 TldD AF_1169 17a850386ad3bb76ceab23ca55d7737e 206 Gene3D G3DSA:1.10.1760.20 2 200 1.9E-40 T 31-10-2018 AF_1169 17a850386ad3bb76ceab23ca55d7737e 206 Pfam PF02632 BioY family 28 195 1.1E-29 T 31-10-2018 IPR003784 BioY protein GO:0005886|GO:0015225|GO:0015878 AF_2046 945c7ce3ec13694f4daadf31cc257cd0 248 PIRSF PIRSF025737 1 248 1.1E-108 T 31-10-2018 IPR014522 Archaeosortase A AF_2046 945c7ce3ec13694f4daadf31cc257cd0 248 Pfam PF09721 Transmembrane exosortase (Exosortase_EpsH) 8 209 9.6E-12 T 31-10-2018 IPR019127 Exosortase AF_2046 945c7ce3ec13694f4daadf31cc257cd0 248 TIGRFAM TIGR04178 exo_archaeo: exosortase/archaeosortase family protein 137 231 1.1E-20 T 31-10-2018 IPR026392 Exosortase/Archaeosortase domain AF_2046 945c7ce3ec13694f4daadf31cc257cd0 248 TIGRFAM TIGR04125 exosort_PGF_TRM: archaeosortase A 4 239 1.5E-64 T 31-10-2018 IPR014522 Archaeosortase A AF_0989 0909ab553574659e53ec50ef4e7aa8a2 643 TIGRFAM TIGR02123 TRAP_fused: TRAP transporter, 4TM/12TM fusion protein 9 637 4.7E-158 T 31-10-2018 IPR011853 TRAP C4-dicarboxylate transport system permease, fused DctM-DctQ AF_0989 0909ab553574659e53ec50ef4e7aa8a2 643 Pfam PF06808 Tripartite ATP-independent periplasmic transporter, DctM component 110 556 3.1E-54 T 31-10-2018 IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit AF_0048 76281612d98fccb89b302eaa29d6cb47 413 SUPERFAMILY SSF52129 22 341 6.49E-17 T 31-10-2018 IPR029030 Caspase-like domain superfamily AF_0048 76281612d98fccb89b302eaa29d6cb47 413 Pfam PF01364 Peptidase family C25 23 379 8.7E-53 T 31-10-2018 IPR001769 Gingipain GO:0006508|GO:0008234 AF_1439 318d066fbcf583342b9e97a116bf8108 371 Pfam PF00733 Asparagine synthase 268 364 4.6E-14 T 31-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 AF_1439 318d066fbcf583342b9e97a116bf8108 371 Pfam PF00733 Asparagine synthase 155 265 3.3E-13 T 31-10-2018 IPR001962 Asparagine synthase GO:0004066|GO:0006529 AF_1439 318d066fbcf583342b9e97a116bf8108 371 Gene3D G3DSA:3.40.50.620 131 370 6.2E-50 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_1439 318d066fbcf583342b9e97a116bf8108 371 SUPERFAMILY SSF52402 133 368 1.33E-35 T 31-10-2018 AF_2265 8a1fb587385dfae59a57deac74c41247 197 SUPERFAMILY SSF52317 2 195 1.48E-49 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_2265 8a1fb587385dfae59a57deac74c41247 197 Hamap MF_00278 Imidazole glycerol phosphate synthase subunit HisH [hisH]. 1 194 35.395 T 31-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AF_2265 8a1fb587385dfae59a57deac74c41247 197 Gene3D G3DSA:3.40.50.880 1 197 1.3E-69 T 31-10-2018 IPR029062 Class I glutamine amidotransferase-like AF_2265 8a1fb587385dfae59a57deac74c41247 197 TIGRFAM TIGR01855 IMP_synth_hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit 2 193 9.8E-69 T 31-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AF_2265 8a1fb587385dfae59a57deac74c41247 197 PIRSF PIRSF000495 1 197 4.5E-71 T 31-10-2018 IPR010139 Imidazole glycerol phosphate synthase, subunit H GO:0000105|GO:0005737|GO:0016763 AF_2265 8a1fb587385dfae59a57deac74c41247 197 Pfam PF00117 Glutamine amidotransferase class-I 4 192 1.1E-23 T 31-10-2018 IPR017926 Glutamine amidotransferase AF_1434 e6ad2eb32fab62417009e0e3eceb9510 199 Pfam PF13886 Domain of unknown function (DUF4203) 18 187 2.4E-13 T 31-10-2018 IPR025256 Domain of unknown function DUF4203 AF_1756 8019ee6ab67f61f96f4f1bb0a0ef4e46 101 SMART SM01078 2 98 1.2E-4 T 31-10-2018 IPR014925 Uncharacterised domain CGGC-dom AF_1756 8019ee6ab67f61f96f4f1bb0a0ef4e46 101 Pfam PF08821 CGGC domain 4 98 7.3E-17 T 31-10-2018 IPR014925 Uncharacterised domain CGGC-dom AF_0124 fcc462efbf377356cd1df7fc61aa9e67 289 Pfam PF01925 Sulfite exporter TauE/SafE 10 276 4.4E-36 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AF_0428 c54fedb8cd254134e028c65639490e5f 328 Pfam PF06858 Nucleolar GTP-binding protein 1 (NOG1) 221 276 2.0E-23 T 31-10-2018 IPR010674 Nucleolar GTP-binding protein 1, Rossman-fold domain GO:0005525 AF_0428 c54fedb8cd254134e028c65639490e5f 328 TIGRFAM TIGR00231 small_GTP: small GTP-binding protein domain 155 297 4.7E-13 T 31-10-2018 IPR005225 Small GTP-binding protein domain GO:0005525 AF_0428 c54fedb8cd254134e028c65639490e5f 328 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 204 219 3.8E-12 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 AF_0428 c54fedb8cd254134e028c65639490e5f 328 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 177 195 3.8E-12 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 AF_0428 c54fedb8cd254134e028c65639490e5f 328 PRINTS PR00326 GTP1/OBG GTP-binding protein family signature 156 176 3.8E-12 T 31-10-2018 IPR006073 GTP binding domain GO:0005525 AF_0428 c54fedb8cd254134e028c65639490e5f 328 Gene3D G3DSA:3.40.50.300 149 317 4.1E-46 T 31-10-2018 AF_0428 c54fedb8cd254134e028c65639490e5f 328 Gene3D G3DSA:1.20.120.1190 1 148 7.8E-37 T 31-10-2018 AF_0428 c54fedb8cd254134e028c65639490e5f 328 SUPERFAMILY SSF52540 147 307 1.98E-36 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_2159 6c1681e02c89a71bc6f58d8382b18dd1 301 PIRSF PIRSF012886 8 301 3.2E-153 T 31-10-2018 IPR016604 Uncharacterised conserved protein UCP012886 AF_0321 e067462bc283cabab67880513ec7a453 324 SUPERFAMILY SSF53448 2 271 1.38E-61 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0321 e067462bc283cabab67880513ec7a453 324 Pfam PF00535 Glycosyl transferase family 2 4 175 2.6E-35 T 31-10-2018 IPR001173 Glycosyltransferase 2-like Reactome: R-HSA-913709 AF_0321 e067462bc283cabab67880513ec7a453 324 Gene3D G3DSA:3.90.550.10 1 218 4.4E-59 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_1861 eb2d757f95efa3a0f014ef6d5318ee71 343 TIGRFAM TIGR01898 cas_TM1791_cmr6: CRISPR type III-B/RAMP module RAMP protein Cmr6 101 338 9.9E-82 T 31-10-2018 IPR010172 CRISPR-associated protein, TM1791 AF_1861 eb2d757f95efa3a0f014ef6d5318ee71 343 Pfam PF03787 RAMP superfamily 104 337 4.8E-14 T 31-10-2018 IPR005537 CRISPR type III-associated RAMP protein AF_1696 99d55b25f3e7f184fae8388848454808 137 Pfam PF06695 Putative small multi-drug export protein 5 125 3.6E-42 T 31-10-2018 IPR009577 Putative small multi-drug export AF_1859 21fbb6df76885d27fa7c2dfd8c0c54ef 289 Gene3D G3DSA:3.30.70.1900 165 288 3.3E-6 T 31-10-2018 AF_0791 f0f0d5f55872458975d531112548ac5c 314 Pfam PF01384 Phosphate transporter family 17 302 4.4E-54 T 31-10-2018 IPR001204 Phosphate transporter GO:0005315|GO:0006817|GO:0016020 Reactome: R-HSA-427652 AF_1138 9a6a0abc9982ed272c89206d0360620e 554 Pfam PF10633 NPCBM-associated, NEW3 domain of alpha-galactosidase 434 507 1.7E-15 T 31-10-2018 IPR018905 Alpha-galactosidase, NEW3 domain AF_1138 9a6a0abc9982ed272c89206d0360620e 554 Pfam PF13620 Carboxypeptidase regulatory-like domain 231 299 1.7E-9 T 31-10-2018 AF_1138 9a6a0abc9982ed272c89206d0360620e 554 Gene3D G3DSA:2.60.40.1120 231 303 6.5E-8 T 31-10-2018 AF_1138 9a6a0abc9982ed272c89206d0360620e 554 SUPERFAMILY SSF49452 227 302 1.29E-7 T 31-10-2018 IPR013784 Carbohydrate-binding-like fold GO:0030246 AF_0732 155212c15315253b65f94e60c4f3061f 163 Pfam PF08241 Methyltransferase domain 28 91 1.8E-4 T 31-10-2018 IPR013216 Methyltransferase type 11 GO:0008168 AF_0732 155212c15315253b65f94e60c4f3061f 163 Hamap MF_00786 Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) [cbiT]. 2 163 26.392 T 31-10-2018 IPR023475 Probable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating) CbiT GO:0008168 KEGG: 00860+2.1.1.196|MetaCyc: PWY-7377 AF_0732 155212c15315253b65f94e60c4f3061f 163 SUPERFAMILY SSF53335 6 101 1.51E-17 T 31-10-2018 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase AF_0732 155212c15315253b65f94e60c4f3061f 163 Gene3D G3DSA:3.40.50.150 1 162 9.4E-32 T 31-10-2018 AF_1229 f4444c3ced8c771cde4dfdb46857d903 750 Pfam PF03176 MMPL family 78 392 2.2E-29 T 31-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AF_1229 f4444c3ced8c771cde4dfdb46857d903 750 Pfam PF03176 MMPL family 561 731 1.1E-27 T 31-10-2018 IPR004869 Membrane transport protein MMPL domain GO:0016020 AF_1229 f4444c3ced8c771cde4dfdb46857d903 750 Gene3D G3DSA:1.20.1640.10 178 375 1.4E-18 T 31-10-2018 AF_1229 f4444c3ced8c771cde4dfdb46857d903 750 Gene3D G3DSA:1.20.1640.10 571 739 1.6E-16 T 31-10-2018 AF_1229 f4444c3ced8c771cde4dfdb46857d903 750 TIGRFAM TIGR00921 2A067: efflux transporter, putative, hydrophobe/amphiphile efflux-3 (HAE3) family 15 731 0.0 T 31-10-2018 IPR004767 Hydrophobe/amphiphile efflux-3 HAE3 AF_1229 f4444c3ced8c771cde4dfdb46857d903 750 SUPERFAMILY SSF82866 147 360 7.19E-35 T 31-10-2018 AF_1229 f4444c3ced8c771cde4dfdb46857d903 750 SUPERFAMILY SSF82866 542 731 4.32E-33 T 31-10-2018 AF_1722 1724b3b7d8d883d6ac0c9e38558f5a55 1143 Hamap MF_00324 DNA polymerase II large subunit [polC]. 1 1143 519.975 T 31-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AF_1722 1724b3b7d8d883d6ac0c9e38558f5a55 1143 TIGRFAM TIGR00354 polC: DNA polymerase II, large subunit DP2 24 1142 0.0 T 31-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AF_1722 1724b3b7d8d883d6ac0c9e38558f5a55 1143 PIRSF PIRSF016275 8 1143 0.0 T 31-10-2018 IPR004475 DNA polymerase II large subunit DP2 GO:0003677|GO:0003887|GO:0006260 KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AF_1722 1724b3b7d8d883d6ac0c9e38558f5a55 1143 Pfam PF03833 DNA polymerase II large subunit DP2 28 893 0.0 T 31-10-2018 IPR016033 DNA polymerase II large subunit DP2, N-terminal KEGG: 00230+2.7.7.7|KEGG: 00240+2.7.7.7 AF_0872 eed0bfdeefe8ac7d236503ae3e64ea23 64 Pfam PF09889 Uncharacterized protein containing a Zn-ribbon (DUF2116) 6 62 1.6E-27 T 31-10-2018 IPR019216 Protein of unknown function DUF2116, Zn-ribbon AF_0872 eed0bfdeefe8ac7d236503ae3e64ea23 64 PIRSF PIRSF004990 1 62 2.3E-37 T 31-10-2018 IPR019216 Protein of unknown function DUF2116, Zn-ribbon AF_1718 b2cdbf1ce004cf62c455443521dd25a0 66 ProDom PD054524 AF1718 3 61 2.0E-27 T 31-10-2018 IPR020073 Uncharacterised protein family AF1718 AF_1718 b2cdbf1ce004cf62c455443521dd25a0 66 Pfam PF17341 Family of unknown function (DUF5371) 4 66 2.4E-32 T 31-10-2018 IPR020073 Uncharacterised protein family AF1718 AF_0392 f4ee70072170d90ea8439999f80c3d96 484 PIRSF PIRSF018875 1 482 1.2E-156 T 31-10-2018 IPR018646 Membrane protein of 12 TMs AF_0392 f4ee70072170d90ea8439999f80c3d96 484 Pfam PF09847 Membrane protein of 12 TMs 39 477 7.4E-132 T 31-10-2018 IPR018646 Membrane protein of 12 TMs AF_0368 4a278d35850819ce83a17678381a2e3f 58 Pfam PF10047 Protein of unknown function (DUF2281) 5 57 3.0E-15 T 31-10-2018 IPR018739 Domain of unknown function DUF2281 AF_0248 feadc8e6613ea74d7d7e696ea674bc67 378 Pfam PF00724 NADH:flavin oxidoreductase / NADH oxidase family 25 349 1.0E-53 T 31-10-2018 IPR001155 NADH:flavin oxidoreductase/NADH oxidase, N-terminal GO:0010181|GO:0016491|GO:0055114 AF_0248 feadc8e6613ea74d7d7e696ea674bc67 378 SUPERFAMILY SSF51395 23 375 5.92E-98 T 31-10-2018 AF_0248 feadc8e6613ea74d7d7e696ea674bc67 378 Gene3D G3DSA:3.20.20.70 23 378 2.0E-112 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1109 87fb929a926b6b0cc2bd5218e2cb6398 113 Pfam PF04434 SWIM zinc finger 49 89 1.7E-8 T 31-10-2018 IPR007527 Zinc finger, SWIM-type GO:0008270 AF_1594 afc32c8217b0712c47f1f1df6d5da25d 243 Gene3D G3DSA:3.30.70.3460 123 243 8.9E-18 T 31-10-2018 AF_1594 afc32c8217b0712c47f1f1df6d5da25d 243 Gene3D G3DSA:3.30.70.3460 1 89 2.2E-15 T 31-10-2018 AF_1544 f0ac58f0f33bd0becde2f6317f7974b3 131 SUPERFAMILY SSF46785 55 126 1.8E-16 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_1544 f0ac58f0f33bd0becde2f6317f7974b3 131 Gene3D G3DSA:1.10.10.10 31 128 1.4E-22 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_1544 f0ac58f0f33bd0becde2f6317f7974b3 131 Pfam PF12840 Helix-turn-helix domain 55 109 1.6E-9 T 31-10-2018 AF_1544 f0ac58f0f33bd0becde2f6317f7974b3 131 SMART SM00418 53 129 1.1E-15 T 31-10-2018 IPR001845 HTH ArsR-type DNA-binding domain GO:0003700|GO:0006355 AF_0043 6d070da3c35790bf013549f701c0446b 363 Gene3D G3DSA:3.40.50.2000 165 338 2.5E-56 T 31-10-2018 AF_0043 6d070da3c35790bf013549f701c0446b 363 SUPERFAMILY SSF53756 3 351 8.48E-58 T 31-10-2018 AF_0043 6d070da3c35790bf013549f701c0446b 363 Pfam PF00534 Glycosyl transferases group 1 186 336 3.2E-32 T 31-10-2018 IPR001296 Glycosyl transferase, family 1 AF_1210 a3b1157a0236b4b80c3cb00e709c4fc9 313 Gene3D G3DSA:3.20.20.70 1 313 3.3E-140 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_1210 a3b1157a0236b4b80c3cb00e709c4fc9 313 Pfam PF05853 beta-keto acid cleavage enzyme 7 305 4.1E-103 T 31-10-2018 IPR008567 3-keto-5-aminohexanoate cleavage enzyme GO:0016740|GO:0019475 KEGG: 00310+2.3.1.247 AF_1210 a3b1157a0236b4b80c3cb00e709c4fc9 313 SUPERFAMILY SSF102114 24 143 1.33E-5 T 31-10-2018 AF_0796 77e9f1734cf0fb3f4b29e0a2f9b60948 204 TIGRFAM TIGR03879 near_KaiC_dom: probable regulatory domain 30 123 3.1E-37 T 31-10-2018 IPR022285 Conserved hypothetical protein CHP03879, regulatory domain, putative AF_1237 662cfc8c917633d0863a9ac3a5375a0c 297 SUPERFAMILY SSF48695 50 283 1.59E-28 T 31-10-2018 IPR036280 Multiheme cytochrome superfamily AF_1201 2d7eae1287196098f0c5584bdcf3c2d8 228 ProDom PD695862 AF1173 AF0136 AF2020 48 191 0.002 T 31-10-2018 AF_1120 c4409cb3e6f9da8e7554c94764e6951f 170 Gene3D G3DSA:3.40.50.1440 4 170 7.6E-7 T 31-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AF_1120 c4409cb3e6f9da8e7554c94764e6951f 170 SUPERFAMILY SSF52490 6 111 2.01E-8 T 31-10-2018 IPR036525 Tubulin/FtsZ, GTPase domain superfamily Reactome: R-HSA-380320 AF_1562 3819a63f3043e2e8fd31019ed62bcdf5 140 ProDom PD085044 MEMBRANE AF1562 TRANSMEMBRANE 31 118 1.0E-45 T 31-10-2018 IPR020327 Uncharacterised protein family AF1562 AF_1589 08a460260145a1961000cb2b9e30efb2 255 SUPERFAMILY SSF102114 24 180 7.19E-6 T 31-10-2018 AF_1589 08a460260145a1961000cb2b9e30efb2 255 Pfam PF04055 Radical SAM superfamily 26 180 5.7E-8 T 31-10-2018 IPR007197 Radical SAM GO:0003824|GO:0051536 AF_0342 27dc2860cf5742f49c60557320a52d80 150 SUPERFAMILY SSF57802 112 145 9.97E-11 T 31-10-2018 AF_0342 27dc2860cf5742f49c60557320a52d80 150 Gene3D G3DSA:2.20.28.10 110 146 2.7E-14 T 31-10-2018 AF_2306 0e51d7786027b20bdd907ea30bb3f6ec 157 Pfam PF03692 Putative zinc- or iron-chelating domain 8 101 3.2E-14 T 31-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein AF_0648 b5cd33f36aa3b87c9af888648de9a242 312 Pfam PF13450 NAD(P)-binding Rossmann-like domain 6 34 6.2E-5 T 31-10-2018 AF_0648 b5cd33f36aa3b87c9af888648de9a242 312 Gene3D G3DSA:3.50.50.60 93 310 4.9E-15 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0648 b5cd33f36aa3b87c9af888648de9a242 312 SUPERFAMILY SSF51905 6 279 9.07E-13 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0027 32130ab80f44d14a134168c41593cbad 102 Gene3D G3DSA:3.30.70.920 3 99 5.1E-5 T 31-10-2018 AF_0027 32130ab80f44d14a134168c41593cbad 102 Pfam PF08734 GYD domain 11 98 3.9E-31 T 31-10-2018 IPR014845 Protein GYD/TTHA1554 AF_0007 a90d1fdd9912bc16d3c368a747550940 417 SUPERFAMILY SSF51726 7 417 3.49E-46 T 31-10-2018 IPR038071 UROD/MetE-like superfamily Reactome: R-HSA-189451 AF_0007 a90d1fdd9912bc16d3c368a747550940 417 Pfam PF01208 Uroporphyrinogen decarboxylase (URO-D) 172 414 8.8E-20 T 31-10-2018 IPR000257 Uroporphyrinogen decarboxylase (URO-D) GO:0004853|GO:0006779 KEGG: 00860+4.1.1.37|MetaCyc: PWY-5531|MetaCyc: PWY-7159|MetaCyc: PWY-7766|Reactome: R-HSA-189451 AF_0616 e176c1a592d1f7b3c0d6630f0aadebd1 533 Pfam PF13231 Dolichyl-phosphate-mannose-protein mannosyltransferase 70 199 1.8E-14 T 31-10-2018 IPR038731 Glycosyltransferase RgtA/B/C/D-like AF_1842 bcc33912d21e7ba9bc045d1c27233535 243 Pfam PF02361 Cobalt transport protein 27 212 3.8E-24 T 31-10-2018 IPR003339 ABC/ECF transporter, transmembrane component AF_1842 bcc33912d21e7ba9bc045d1c27233535 243 TIGRFAM TIGR02454 ECF_T_CbiQ: cobalt ECF transporter T component CbiQ 33 211 9.6E-42 T 31-10-2018 IPR012809 Cobalt ECF transporter T component CbiQ GO:0005887|GO:0006824|GO:0043190 AF_0060 fdecfc55f5e574b78300a34b80b63cab 93 Gene3D G3DSA:1.10.287.1080 1 93 1.6E-62 T 31-10-2018 AF_0060 fdecfc55f5e574b78300a34b80b63cab 93 Pfam PF03819 MazG nucleotide pyrophosphohydrolase domain 35 70 7.1E-7 T 31-10-2018 IPR004518 NTP pyrophosphohydrolase MazG, putative catalytic core AF_0060 fdecfc55f5e574b78300a34b80b63cab 93 SUPERFAMILY SSF101386 1 84 2.47E-55 T 31-10-2018 AF_0242 1014a72ba25d098a564e711bc44e839b 332 Gene3D G3DSA:2.160.10.10 240 332 1.0E-6 T 31-10-2018 AF_0242 1014a72ba25d098a564e711bc44e839b 332 Gene3D G3DSA:3.90.550.10 1 239 1.8E-50 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0242 1014a72ba25d098a564e711bc44e839b 332 SUPERFAMILY SSF53448 1 279 2.25E-48 T 31-10-2018 IPR029044 Nucleotide-diphospho-sugar transferases AF_0242 1014a72ba25d098a564e711bc44e839b 332 Pfam PF00483 Nucleotidyl transferase 2 236 2.7E-48 T 31-10-2018 IPR005835 Nucleotidyl transferase domain GO:0009058|GO:0016779 AF_0242 1014a72ba25d098a564e711bc44e839b 332 SUPERFAMILY SSF51161 237 329 5.42E-11 T 31-10-2018 IPR011004 Trimeric LpxA-like superfamily AF_1421 6d9fdf15a504fb05640a0a02aa3d763a 880 Pfam PF03699 Uncharacterised protein family (UPF0182) 21 755 1.7E-243 T 31-10-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 AF_1421 6d9fdf15a504fb05640a0a02aa3d763a 880 Hamap MF_01600 UPF0182 protein . 12 830 18.266 T 31-10-2018 IPR005372 Uncharacterised protein family UPF0182 GO:0016021 AF_0058 6a8e665742c8a49a34835e312297f867 174 Pfam PF03657 Uncharacterised protein family (UPF0113) 1 167 3.6E-73 T 31-10-2018 IPR005155 Ribosome biogenesis factor NIP7-like Reactome: R-HSA-6791226 AF_0058 6a8e665742c8a49a34835e312297f867 174 SUPERFAMILY SSF88697 88 162 1.93E-12 T 31-10-2018 IPR015947 PUA-like superfamily AF_0058 6a8e665742c8a49a34835e312297f867 174 SMART SM00359 88 166 3.2E-17 T 31-10-2018 IPR002478 PUA domain GO:0003723 AF_0058 6a8e665742c8a49a34835e312297f867 174 Gene3D G3DSA:2.30.130.10 87 167 7.4E-26 T 31-10-2018 IPR036974 PUA domain superfamily GO:0003723 AF_1245 1fb99d64c06b7f5571581e627dd0ed37 338 Gene3D G3DSA:1.20.1530.20 1 338 8.5E-40 T 31-10-2018 IPR038770 Sodium/solute symporter superfamily AF_1245 1fb99d64c06b7f5571581e627dd0ed37 338 Pfam PF00999 Sodium/hydrogen exchanger family 5 335 2.2E-33 T 31-10-2018 IPR006153 Cation/H+ exchanger GO:0006812|GO:0015299|GO:0016021|GO:0055085 AF_0595 f0d7e4867c46697e7261ff538e296b18 482 Pfam PF01943 Polysaccharide biosynthesis protein 6 284 2.1E-69 T 31-10-2018 IPR002797 Polysaccharide biosynthesis protein GO:0016020 AF_0595 f0d7e4867c46697e7261ff538e296b18 482 Pfam PF14667 Polysaccharide biosynthesis C-terminal domain 335 465 7.5E-18 T 31-10-2018 IPR029303 Polysaccharide biosynthesis protein, C-terminal domain AF_1738 91ce6a9c01e552a405e7060964d44f67 404 SUPERFAMILY SSF51905 1 399 9.71E-28 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_1738 91ce6a9c01e552a405e7060964d44f67 404 Pfam PF01593 Flavin containing amine oxidoreductase 10 399 1.7E-33 T 31-10-2018 IPR002937 Amine oxidase GO:0016491|GO:0055114 AF_1738 91ce6a9c01e552a405e7060964d44f67 404 Gene3D G3DSA:3.50.50.60 1 403 5.0E-25 T 31-10-2018 IPR036188 FAD/NAD(P)-binding domain superfamily AF_0908 3a9e707e7474e5381f583cad3b2f36dd 251 Pfam PF02596 Uncharacterised ArCR, COG2043 12 211 4.2E-46 T 31-10-2018 IPR003748 Protein of unknown function DUF169 AF_0391 ac815095ae09270a944b92ed16901ba5 152 PIRSF PIRSF018748 4 152 4.0E-40 T 31-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding AF_0391 ac815095ae09270a944b92ed16901ba5 152 Pfam PF10050 Predicted metal-binding protein (DUF2284) 25 145 9.4E-21 T 31-10-2018 IPR019271 Protein of unknown function DUF2284, metal-binding AF_1103 9718611a24d9b3994a53f0fdf62ce979 182 Pfam PF04250 Protein of unknown function (DUF429) 19 157 2.3E-11 T 31-10-2018 IPR007362 Protein of unknown function DUF429 AF_1103 9718611a24d9b3994a53f0fdf62ce979 182 PIRSF PIRSF024051 1 182 2.1E-60 T 31-10-2018 IPR018036 Protein of unknown function DUF429, subgroup AF_2223 679b43d505dd2c5e1da1b14785a62d26 52 Pfam PF09853 Putative transposon-encoded protein (DUF2080) 4 52 4.5E-23 T 31-10-2018 IPR019205 Protein of unknown function DUF2080, transposon-encoded AF_0559 2d8fd2e3a87b2da2df8c0144aa61b923 265 SUPERFAMILY SSF52402 20 218 1.52E-34 T 31-10-2018 AF_0559 2d8fd2e3a87b2da2df8c0144aa61b923 265 Pfam PF02540 NAD synthase 17 90 2.4E-9 T 31-10-2018 IPR022310 NAD/GMP synthase AF_0559 2d8fd2e3a87b2da2df8c0144aa61b923 265 Gene3D G3DSA:3.40.50.620 4 169 1.3E-25 T 31-10-2018 IPR014729 Rossmann-like alpha/beta/alpha sandwich fold AF_0559 2d8fd2e3a87b2da2df8c0144aa61b923 265 PIRSF PIRSF006661 2 264 1.5E-101 T 31-10-2018 IPR005232 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase LarE GO:0016783 AF_0559 2d8fd2e3a87b2da2df8c0144aa61b923 265 TIGRFAM TIGR00268 TIGR00268: TIGR00268 family protein 8 262 8.0E-127 T 31-10-2018 IPR005232 Pyridinium-3,5-bisthiocarboxylic acid mononucleotide synthase LarE GO:0016783 AF_0318 7486f9397932cbda689613c976b72435 151 SMART SM00670 3 142 1.2E-25 T 31-10-2018 IPR002716 PIN domain AF_0318 7486f9397932cbda689613c976b72435 151 SUPERFAMILY SSF88723 1 145 1.12E-16 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_0318 7486f9397932cbda689613c976b72435 151 Pfam PF01850 PIN domain 5 146 2.9E-29 T 31-10-2018 IPR002716 PIN domain AF_0318 7486f9397932cbda689613c976b72435 151 Gene3D G3DSA:3.40.50.1010 3 150 1.3E-9 T 31-10-2018 AF_2392 4cd8bb4ca834089edacff4407127844e 86 Pfam PF17253 Family of unknown function (DUF5320) 10 80 5.3E-10 T 31-10-2018 IPR035205 Protein of unknown function DUF5320 AF_0291 67b76345c37e333667a315daf470f2e3 314 SUPERFAMILY SSF64182 6 313 4.71E-25 T 31-10-2018 IPR038763 DHH phosphoesterase superfamily AF_1812 f757b2da6e1d15ba1a21cddcf2f6a423 177 SUPERFAMILY SSF88697 2 98 4.22E-17 T 31-10-2018 IPR015947 PUA-like superfamily AF_1812 f757b2da6e1d15ba1a21cddcf2f6a423 177 Pfam PF04266 ASCH domain 4 89 8.0E-15 T 31-10-2018 IPR007374 ASCH domain AF_1812 f757b2da6e1d15ba1a21cddcf2f6a423 177 SMART SM01022 4 98 2.8E-20 T 31-10-2018 IPR007374 ASCH domain AF_1814 01acdffc2c0c69a301943aff3b7a0b3f 118 Pfam PF06935 Protein of unknown function (DUF1284) 18 116 6.4E-23 T 31-10-2018 IPR009702 Protein of unknown function DUF1284 AF_1619 bb28a799c3b5c54c95f117ce567394fd 319 Pfam PF03601 Conserved hypothetical protein 698 143 312 1.2E-17 T 31-10-2018 IPR018383 Uncharacterised protein family UPF0324, prokaryote GO:0016021 AF_0486 96a4dfed289b86c753b509e839147bd4 128 Pfam PF03692 Putative zinc- or iron-chelating domain 17 99 4.5E-12 T 31-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein AF_0067 6760459436dc42c0db2e63798c9e339a 228 TIGRFAM TIGR02593 CRISPR_cas5: CRISPR-associated protein Cas5 3 43 2.6E-10 T 31-10-2018 IPR013422 CRISPR-associated protein Cas5, N-terminal AF_2143 94dd24ac6ec83900eb812505a8032a0d 129 SUPERFAMILY SSF46785 19 113 3.14E-11 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_2143 94dd24ac6ec83900eb812505a8032a0d 129 Gene3D G3DSA:1.10.10.10 2 119 2.2E-32 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_2143 94dd24ac6ec83900eb812505a8032a0d 129 Pfam PF01978 Sugar-specific transcriptional regulator TrmB 17 89 1.4E-15 T 31-10-2018 IPR002831 Transcription regulator TrmB, N-terminal AF_0350 37c5c5dfcf5e0d7ce68cb7f46dd74d9d 211 Pfam PF01925 Sulfite exporter TauE/SafE 135 190 6.8E-10 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AF_0369 b76ef5ba620b8fee4fb158221bdd7ba2 45 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 11 33 2.2E-6 T 31-10-2018 IPR013373 Flagellin/pilin, N-terminal AF_2086 127705081c30345aabc5a38bf93a1b99 93 TIGRFAM TIGR01195 oadG_fam: sodium pump decarboxylases, gamma subunit 1 70 1.0E-19 T 31-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 AF_2086 127705081c30345aabc5a38bf93a1b99 93 Pfam PF04277 Oxaloacetate decarboxylase, gamma chain 5 64 1.6E-7 T 31-10-2018 IPR005899 Sodium ion-translocating decarboxylase GO:0008948|GO:0015081|GO:0016020|GO:0036376 KEGG: 00620+4.1.1.3 AF_2023 d0322dd807cd0499c397febd35e7d560 298 SUPERFAMILY SSF51679 18 297 6.39E-10 T 31-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AF_2023 d0322dd807cd0499c397febd35e7d560 298 Gene3D G3DSA:3.20.20.30 12 298 2.4E-8 T 31-10-2018 IPR036661 Luciferase-like domain superfamily GO:0016705|GO:0055114 AF_1154 3e1684e59ba54ec6c6b3dcbfbb00a761 195 Gene3D G3DSA:3.40.50.300 2 193 1.9E-5 T 31-10-2018 AF_1429 ad56fed04a567382e11c88df38086819 217 Pfam PF04967 HTH DNA binding domain 150 202 3.8E-20 T 31-10-2018 IPR007050 Bacterioopsin activator-type, HTH domain AF_2232 b7d6eaa427fe4b558858b1a036898903 128 SUPERFAMILY SSF46785 4 111 1.63E-18 T 31-10-2018 IPR036390 Winged helix DNA-binding domain superfamily AF_2232 b7d6eaa427fe4b558858b1a036898903 128 Pfam PF01475 Ferric uptake regulator family 12 125 4.2E-24 T 31-10-2018 IPR002481 Ferric-uptake regulator GO:0003700|GO:0006355 AF_2232 b7d6eaa427fe4b558858b1a036898903 128 Gene3D G3DSA:1.10.10.10 3 82 7.2E-18 T 31-10-2018 IPR036388 Winged helix-like DNA-binding domain superfamily AF_2279 ed96d597ca13b5ff60ae733049cfb237 84 Pfam PF01998 Protein of unknown function DUF131 40 82 4.0E-14 T 31-10-2018 IPR002849 Protein of unknown function DUF131 AF_2279 ed96d597ca13b5ff60ae733049cfb237 84 TIGRFAM TIGR00304 TIGR00304: TIGR00304 family protein 8 81 4.4E-26 T 31-10-2018 IPR002849 Protein of unknown function DUF131 AF_2386 160510a388ddd9dfddf4812fec15105c 305 Pfam PF03916 Polysulphide reductase, NrfD 14 301 5.4E-73 T 31-10-2018 IPR005614 NrfD family AF_2172 45e1610c3ffb4d12690fd8088cb312d1 307 Pfam PF00882 Zinc dependent phospholipase C 13 169 5.9E-9 T 31-10-2018 IPR029002 Phospholipase C/D Reactome: R-HSA-163125 AF_0593 8a4a965c593b55f6ebab6cb744aef99f 128 SUPERFAMILY SSF81593 10 124 5.89E-32 T 31-10-2018 AF_0593 8a4a965c593b55f6ebab6cb744aef99f 128 Gene3D G3DSA:1.20.120.330 3 125 5.9E-30 T 31-10-2018 AF_0593 8a4a965c593b55f6ebab6cb744aef99f 128 Pfam PF05168 HEPN domain 7 122 4.1E-34 T 31-10-2018 IPR007842 HEPN domain AF_0593 8a4a965c593b55f6ebab6cb744aef99f 128 SMART SM00748 11 116 8.4E-40 T 31-10-2018 IPR007842 HEPN domain AF_0307 c0226d907af3083edbb773557da0a988 253 SUPERFAMILY SSF52540 5 239 5.84E-7 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_0307 c0226d907af3083edbb773557da0a988 253 Gene3D G3DSA:3.40.50.300 4 245 4.0E-6 T 31-10-2018 AF_0116 7f8170e7104e0836faa928753c6bc7c6 226 Gene3D G3DSA:3.40.50.10090 1 102 2.2E-7 T 31-10-2018 AF_0116 7f8170e7104e0836faa928753c6bc7c6 226 SUPERFAMILY SSF69618 1 222 8.63E-41 T 31-10-2018 IPR036108 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase superfamily GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AF_0116 7f8170e7104e0836faa928753c6bc7c6 226 Gene3D G3DSA:3.40.50.10090 103 225 3.5E-18 T 31-10-2018 AF_0116 7f8170e7104e0836faa928753c6bc7c6 226 Pfam PF02602 Uroporphyrinogen-III synthase HemD 14 218 6.1E-29 T 31-10-2018 IPR003754 Tetrapyrrole biosynthesis, uroporphyrinogen III synthase GO:0004852|GO:0033014 KEGG: 00860+4.2.1.75|MetaCyc: PWY-5188|MetaCyc: PWY-5189|Reactome: R-HSA-189451 AF_2089 9cf0ea4009c37f1f85362c9ae1721018 313 TIGRFAM TIGR00144 beta_RFAP_syn: beta-ribofuranosylaminobenzene 5'-phosphate synthase family 2 312 4.9E-168 T 31-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 AF_2089 9cf0ea4009c37f1f85362c9ae1721018 313 SUPERFAMILY SSF54211 3 141 3.87E-17 T 31-10-2018 IPR020568 Ribosomal protein S5 domain 2-type fold AF_2089 9cf0ea4009c37f1f85362c9ae1721018 313 PIRSF PIRSF004884 1 313 1.0E-128 T 31-10-2018 IPR004422 GHMP kinase group 1 KEGG: 00790+2.4.2.54|MetaCyc: PWY-6148 AF_2089 9cf0ea4009c37f1f85362c9ae1721018 313 Pfam PF00288 GHMP kinases N terminal domain 76 136 2.3E-7 T 31-10-2018 IPR006204 GHMP kinase N-terminal domain GO:0005524 AF_2089 9cf0ea4009c37f1f85362c9ae1721018 313 Gene3D G3DSA:3.30.230.10 21 145 1.5E-8 T 31-10-2018 IPR014721 Ribosomal protein S5 domain 2-type fold, subgroup AF_1123 7e7b13e48e3bde843acc6729ea8e96be 71 Gene3D G3DSA:3.40.50.1820 1 71 1.1E-9 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_1123 7e7b13e48e3bde843acc6729ea8e96be 71 SUPERFAMILY SSF53474 1 66 9.55E-10 T 31-10-2018 IPR029058 Alpha/Beta hydrolase fold AF_1123 7e7b13e48e3bde843acc6729ea8e96be 71 Pfam PF12146 Serine aminopeptidase, S33 2 42 1.3E-6 T 31-10-2018 IPR022742 Serine aminopeptidase, S33 AF_2173 5e99f46739e895547333e8e0304e1202 274 Gene3D G3DSA:3.20.20.70 1 273 3.7E-86 T 31-10-2018 IPR013785 Aldolase-type TIM barrel GO:0003824 AF_2173 5e99f46739e895547333e8e0304e1202 274 SUPERFAMILY SSF51412 2 212 1.53E-57 T 31-10-2018 AF_2173 5e99f46739e895547333e8e0304e1202 274 Pfam PF03060 Nitronate monooxygenase 4 73 5.6E-20 T 31-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 AF_2173 5e99f46739e895547333e8e0304e1202 274 Pfam PF03060 Nitronate monooxygenase 79 240 2.4E-36 T 31-10-2018 IPR004136 Nitronate monooxygenase GO:0018580|GO:0055114 KEGG: 00910+1.13.12.16|MetaCyc: PWY-723 AF_2044 22114634b256f9e4143ce0cd987bab62 221 TIGRFAM TIGR00473 pssA: CDP-diacylglycerol-serine O-phosphatidyltransferase 14 160 9.9E-54 T 31-10-2018 IPR004533 CDP-diacylglycerol--serine O-phosphatidyltransferase KEGG: 00260+2.7.8.8|KEGG: 00564+2.7.8.8|MetaCyc: PWY-5669 AF_2044 22114634b256f9e4143ce0cd987bab62 221 Pfam PF01066 CDP-alcohol phosphatidyltransferase 9 72 1.5E-10 T 31-10-2018 IPR000462 CDP-alcohol phosphatidyltransferase GO:0008654|GO:0016020|GO:0016780 AF_0500 5598a350aeacd4dc62cb98094f5d24ea 395 Pfam PF03916 Polysulphide reductase, NrfD 42 331 5.2E-71 T 31-10-2018 IPR005614 NrfD family AF_0485 789ef2bf71f750168b0fcc54c93598d1 245 Pfam PF09876 Predicted metal-binding protein (DUF2103) 141 236 9.9E-37 T 31-10-2018 IPR018664 Protein of unknown function DUF2103, metal-binding AF_0679 17fe31b06c0aa5937ce9ebd55a2c1d9a 141 Pfam PF13358 DDE superfamily endonuclease 6 113 2.4E-23 T 31-10-2018 IPR038717 Tc1-like transposase, DDE domain AF_0679 17fe31b06c0aa5937ce9ebd55a2c1d9a 141 SUPERFAMILY SSF53098 29 126 3.54E-7 T 31-10-2018 IPR012337 Ribonuclease H-like superfamily AF_0679 17fe31b06c0aa5937ce9ebd55a2c1d9a 141 Gene3D G3DSA:3.30.420.470 7 138 2.1E-17 T 31-10-2018 AF_1607 f10eac687391a5c7b6ee3778c1d07c05 248 SUPERFAMILY SSF161098 4 240 8.78E-51 T 31-10-2018 IPR035906 MetI-like superfamily AF_1607 f10eac687391a5c7b6ee3778c1d07c05 248 Pfam PF00528 Binding-protein-dependent transport system inner membrane component 69 237 2.3E-13 T 31-10-2018 IPR000515 ABC transporter type 1, transmembrane domain MetI-like GO:0016020|GO:0055085 AF_1607 f10eac687391a5c7b6ee3778c1d07c05 248 Gene3D G3DSA:1.10.3720.10 2 245 8.1E-48 T 31-10-2018 IPR035906 MetI-like superfamily AF_0573 e148cbb2499aaf6fb2150370fb7814b0 54 Pfam PF07754 Domain of unknown function (DUF1610) 7 29 4.5E-11 T 31-10-2018 IPR011668 Domain of unknown function DUF1610 AF_0163 17b0ce60736dfe01c7274f199aba6bed 183 Pfam PF07853 Protein of unknown function (DUF1648) 22 66 1.6E-16 T 31-10-2018 IPR012867 Domain of unknown function DUF1648 AF_0079 f4ec08942be980782def202d8fe7d62a 431 Pfam PF01629 Domain of unknown function DUF22 2 109 2.8E-32 T 31-10-2018 IPR002572 Domain of unknown function DUF22 AF_0079 f4ec08942be980782def202d8fe7d62a 431 Pfam PF01629 Domain of unknown function DUF22 149 254 9.1E-39 T 31-10-2018 IPR002572 Domain of unknown function DUF22 AF_0079 f4ec08942be980782def202d8fe7d62a 431 Pfam PF01629 Domain of unknown function DUF22 288 393 1.4E-34 T 31-10-2018 IPR002572 Domain of unknown function DUF22 AF_0604 a9ca592cb09611405e744a89617e9ff7 120 SUPERFAMILY SSF52540 17 99 2.86E-6 T 31-10-2018 IPR027417 P-loop containing nucleoside triphosphate hydrolase AF_1626 1252cf353e9486182d55ec854209a449 120 Pfam PF09946 Predicted membrane protein (DUF2178) 9 107 1.9E-27 T 31-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane AF_2181 9fc5dc3693ed305d72ed04dde2d4d93e 212 Pfam PF01930 Domain of unknown function DUF83 141 201 2.9E-5 T 31-10-2018 IPR022765 Dna2/Cas4, domain of unknown function DUF83 AF_0657 aac028ce3d26789ec473ca58957ff5ba 145 Gene3D G3DSA:2.60.40.10 19 115 2.0E-5 T 31-10-2018 IPR013783 Immunoglobulin-like fold AF_2433 c68bb6f494f4acb905ced395869dee1b 119 Gene3D G3DSA:1.20.120.580 4 118 3.1E-13 T 31-10-2018 IPR037038 Bsu32300-like superfamily AF_2433 c68bb6f494f4acb905ced395869dee1b 119 Pfam PF01934 Protein of unknown function DUF86 12 109 9.4E-23 T 31-10-2018 IPR008201 Protein of unknown function DUF86 AF_1514 3e3e5fbd58696df9af4f677fe4a55c4b 91 Gene3D G3DSA:3.30.1490.340 1 91 1.8E-46 T 31-10-2018 AF_2080 797660844c18e240fa228151b9e9b582 177 Pfam PF06510 Protein of unknown function (DUF1102) 37 176 4.6E-59 T 31-10-2018 IPR009482 Protein of unknown function DUF1102 AF_0558 3d1a45977984de4c7dddc6a8947cc45c 137 Pfam PF07849 Protein of unknown function (DUF1641) 99 135 4.5E-16 T 31-10-2018 IPR012440 Protein of unknown function DUF1641 AF_1895 ee772d21166ec8001ab8aa93d378bb85 209 Pfam PF03692 Putative zinc- or iron-chelating domain 19 120 3.1E-14 T 31-10-2018 IPR005358 Putative zinc- or iron-chelating domain containing protein AF_0960 4015ed9f7187e8681bf5079788ac7879 285 Pfam PF02653 Branched-chain amino acid transport system / permease component 28 272 5.9E-33 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AF_0516 73dd4710125f0902cf3a018db7887838 99 Gene3D G3DSA:3.30.1640.10 4 85 2.0E-14 T 31-10-2018 AF_0496 132a338aa2ad66ee63f9076daac1e0f9 175 Pfam PF04893 Yip1 domain 20 162 7.8E-20 T 31-10-2018 IPR006977 Yip1 domain GO:0016020 AF_0100 38f9a1ba8d8e6321df8e6432b3527fad 93 Pfam PF03683 Uncharacterised protein family (UPF0175) 22 88 1.4E-16 T 31-10-2018 IPR005368 Uncharacterised protein family UPF0175 AF_0301 77470e7a3a36749f354844ca340d3e86 67 Pfam PF10047 Protein of unknown function (DUF2281) 5 61 2.2E-19 T 31-10-2018 IPR018739 Domain of unknown function DUF2281 AF_0809 f827d780aad2de288594185f8d9e350f 300 Pfam PF02754 Cysteine-rich domain 205 286 1.1E-6 T 31-10-2018 IPR004017 Cysteine-rich domain AF_1205 4ac8a6896347f0b079a877cee18c77ae 474 Pfam PF00474 Sodium:solute symporter family 25 404 2.6E-28 T 31-10-2018 IPR001734 Sodium/solute symporter GO:0016020|GO:0022857|GO:0055085 AF_1205 4ac8a6896347f0b079a877cee18c77ae 474 Gene3D G3DSA:1.20.1730.10 14 465 1.5E-63 T 31-10-2018 IPR038377 Sodium/glucose symporter superfamily AF_2291 24f4e2b8566e0e798424006df71a2d17 261 SUPERFAMILY SSF49899 110 250 2.27E-6 T 31-10-2018 IPR013320 Concanavalin A-like lectin/glucanase domain superfamily AF_1678 6a68f2b39c0d52c1315c749eac2cf14d 207 SUPERFAMILY SSF55718 1 205 3.83E-28 T 31-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AF_1678 6a68f2b39c0d52c1315c749eac2cf14d 207 Pfam PF02036 SCP-2 sterol transfer family 100 190 7.4E-20 T 31-10-2018 IPR003033 SCP2 sterol-binding domain AF_1678 6a68f2b39c0d52c1315c749eac2cf14d 207 Gene3D G3DSA:3.30.1050.10 79 201 2.5E-19 T 31-10-2018 IPR036527 SCP2 sterol-binding domain superfamily AF_0132 d68d9173c9f4e59286495a5040f8c905 157 Pfam PF12172 Rubredoxin-like zinc ribbon domain (DUF35_N) 23 52 9.3E-9 T 31-10-2018 IPR022002 Domain of unknown function DUF35, rubredoxin-like zinc ribbon domain, N-terminal AF_0132 d68d9173c9f4e59286495a5040f8c905 157 SUPERFAMILY SSF50249 14 140 9.25E-21 T 31-10-2018 IPR012340 Nucleic acid-binding, OB-fold AF_0132 d68d9173c9f4e59286495a5040f8c905 157 Gene3D G3DSA:1.10.12.20 1 59 4.2E-17 T 31-10-2018 AF_0127 083097d7bf2d0ab43e4608b9628fbbbe 475 Pfam PF01925 Sulfite exporter TauE/SafE 28 296 1.9E-34 T 31-10-2018 IPR002781 Transmembrane protein TauE-like GO:0016021 AF_1428 5e0c5aafb82f9eeb2a5cf26e88b394ca 500 Pfam PF09959 Uncharacterized protein conserved in archaea (DUF2193) 4 500 5.5E-280 T 31-10-2018 IPR018694 Protein of unknown function DUF2193 AF_1313 c590915453cfdeb25d5b8f6e249cc830 256 Pfam PF02596 Uncharacterised ArCR, COG2043 15 217 1.5E-39 T 31-10-2018 IPR003748 Protein of unknown function DUF169 AF_0180 f44e6956576f821951340566113d2d2c 286 Pfam PF02596 Uncharacterised ArCR, COG2043 52 149 1.2E-15 T 31-10-2018 IPR003748 Protein of unknown function DUF169 AF_1625 f127836e0e702c5771fe3a988f33e014 581 SUPERFAMILY SSF49373 289 366 1.2E-5 T 31-10-2018 IPR008964 Invasin/intimin cell-adhesion fragments AF_1625 f127836e0e702c5771fe3a988f33e014 581 Gene3D G3DSA:2.60.40.10 275 371 1.0E-6 T 31-10-2018 IPR013783 Immunoglobulin-like fold AF_1613 c437ddc4dec4181fd853673c54a58234 113 Gene3D G3DSA:3.30.460.10 21 113 9.4E-28 T 31-10-2018 AF_1613 c437ddc4dec4181fd853673c54a58234 113 SUPERFAMILY SSF81301 25 110 7.55E-18 T 31-10-2018 AF_1613 c437ddc4dec4181fd853673c54a58234 113 Pfam PF01909 Nucleotidyltransferase domain 25 101 3.0E-13 T 31-10-2018 IPR002934 Polymerase, nucleotidyl transferase domain GO:0016779 AF_0656 668dcb1ca9b8e73224997a269460bdb5 391 SUPERFAMILY SSF111283 2 390 9.68E-69 T 31-10-2018 IPR036059 Metalloprotease TldD/PmbA superfamily GO:0006508|GO:0008237 AF_0656 668dcb1ca9b8e73224997a269460bdb5 391 Pfam PF01523 Putative modulator of DNA gyrase 2 272 3.0E-48 T 31-10-2018 IPR002510 Metalloprotease TldD/PmbA GO:0006508|GO:0008237 AF_0656 668dcb1ca9b8e73224997a269460bdb5 391 Gene3D G3DSA:3.30.2290.10 1 182 4.9E-10 T 31-10-2018 IPR035068 Metalloprotease TldD/PmbA, N-terminal AF_1487 6bcc00403353058d1536244f909dc5b2 219 TIGRFAM TIGR04126 PGF_CTERM: PGF-CTERM archaeal protein-sorting signal 193 216 8.4E-7 T 31-10-2018 IPR026371 PGF-CTERM archaeal protein-sorting signal AF_2093 533a6baeee26689da05b1167ffa56701 245 Gene3D G3DSA:3.40.50.10670 131 226 1.4E-46 T 31-10-2018 AF_2093 533a6baeee26689da05b1167ffa56701 245 Gene3D G3DSA:1.10.3400.10 1 130 3.3E-68 T 31-10-2018 IPR023291 Af2093, N-terminal AF_1208 197bf561aba632a9c66941884973820a 114 SUPERFAMILY SSF51182 1 112 3.06E-21 T 31-10-2018 IPR011051 RmlC-like cupin domain superfamily AF_1208 197bf561aba632a9c66941884973820a 114 Gene3D G3DSA:2.60.120.10 1 114 6.4E-18 T 31-10-2018 IPR014710 RmlC-like jelly roll fold AF_1208 197bf561aba632a9c66941884973820a 114 Pfam PF07883 Cupin domain 40 108 2.6E-11 T 31-10-2018 IPR013096 Cupin 2, conserved barrel AF_1618 b4e73c6df545866d82f5484f7122abed 187 ProDom PD968187 BETA-DEFENSIN ANTIBIOTIC PRECURSOR ANTIMICROBIAL DEFENSIN BETA SIGNAL DEFENSIN BD-32 DEFB-32 8 177 1.0E-95 T 31-10-2018 AF_0540 f3378ecc1d0401e90ca3e79ef899903b 228 SUPERFAMILY SSF90257 94 205 5.75E-5 T 31-10-2018 AF_1363 db27d9c4f0eb20a67427ba303bd65545 87 Pfam PF09868 Uncharacterized protein conserved in archaea (DUF2095) 25 82 4.5E-8 T 31-10-2018 IPR018662 Protein of unknown function DUF2095 AF_0121 5d54ca15eac5b500bc874d55e25ce2c9 255 Pfam PF01629 Domain of unknown function DUF22 3 110 9.4E-40 T 31-10-2018 IPR002572 Domain of unknown function DUF22 AF_0121 5d54ca15eac5b500bc874d55e25ce2c9 255 Pfam PF01629 Domain of unknown function DUF22 150 253 2.5E-33 T 31-10-2018 IPR002572 Domain of unknown function DUF22 AF_0138 089c3606547cbbbf77a25d163b0df2fc 143 Pfam PF13610 DDE domain 55 133 1.3E-13 T 31-10-2018 IPR032874 DDE domain AF_0719 db0a7c449733948426b543013cba98a6 190 Gene3D G3DSA:3.60.15.10 1 190 2.4E-40 T 31-10-2018 IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like AF_1860 45c15a58d737183c2cba07cfa0295014 57 Gene3D G3DSA:1.20.120.580 1 56 4.4E-5 T 31-10-2018 IPR037038 Bsu32300-like superfamily AF_1658 3a7fadb5adad16c1b0ff3d01cd927754 310 Pfam PF12389 Camelysin metallo-endopeptidase 9 192 2.3E-9 T 31-10-2018 IPR022121 Peptidase M73, camelysin AF_1658 3a7fadb5adad16c1b0ff3d01cd927754 310 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 6 37 1.6E-7 T 31-10-2018 IPR023833 Signal peptide, camelysin AF_0802 e3347d282154bba63d89fe4d1cba81d1 214 Pfam PF09622 Putative integral membrane protein (DUF2391) 88 209 1.8E-8 T 31-10-2018 IPR024464 Protein of unknown function DUF2391 AF_1353 d7da31d612b484ebb53a252d94156143 353 Gene3D G3DSA:2.130.10.10 28 352 8.5E-7 T 31-10-2018 IPR015943 WD40/YVTN repeat-like-containing domain superfamily GO:0005515 AF_1353 d7da31d612b484ebb53a252d94156143 353 SUPERFAMILY SSF50998 36 352 3.77E-13 T 31-10-2018 IPR011047 Quinoprotein alcohol dehydrogenase-like superfamily AF_1792 8bed1014fd4ab1b869ab3046486e1de8 137 Pfam PF09946 Predicted membrane protein (DUF2178) 26 124 3.4E-28 T 31-10-2018 IPR019235 Protein of unknown function DUF2178, transmembrane AF_0063 a5c1b717afa925aeef36f59ebbb35f11 61 SUPERFAMILY SSF88723 2 57 2.75E-6 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_0658 0166ef5dabb16ea08f2e68c32b8ee21b 614 Gene3D G3DSA:1.20.81.30 406 522 2.1E-14 T 31-10-2018 AF_0658 0166ef5dabb16ea08f2e68c32b8ee21b 614 Pfam PF00482 Type II secretion system (T2SS), protein F 130 258 2.5E-18 T 31-10-2018 IPR018076 Type II secretion system F domain AF_0658 0166ef5dabb16ea08f2e68c32b8ee21b 614 Pfam PF00482 Type II secretion system (T2SS), protein F 414 539 1.9E-19 T 31-10-2018 IPR018076 Type II secretion system F domain AF_2296 ecb684355803754c72dec523b8424155 362 Pfam PF01654 Cytochrome bd terminal oxidase subunit I 12 199 5.1E-13 T 31-10-2018 IPR002585 Cytochrome ubiquinol oxidase subunit 1 GO:0009055|GO:0019646|GO:0070069 AF_0859 aab2639c58f5bf25958fdfe5f9b4f73b 373 Pfam PF14811 Protein of unknown function TPD sequence-motif 106 232 4.0E-37 T 31-10-2018 IPR029404 Protein of unknown function with TPD sequence-motif AF_0615 1122a54d761d5af2e37c14d325e7a7f4 129 Pfam PF04138 GtrA-like protein 9 128 5.8E-26 T 31-10-2018 IPR007267 GtrA-like protein GO:0000271|GO:0016021 AF_1480 551858b63e3bcae061e6f0ea288be063 53 SUPERFAMILY SSF88723 1 43 3.36E-5 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_0759 e42b88a8862e83378b678faef07547cb 262 TIGRFAM TIGR02537 arch_flag_Nterm: archaeal flagellin N-terminal-like domain 8 30 1.8E-4 T 31-10-2018 IPR013373 Flagellin/pilin, N-terminal AF_0178 39c88bc97c9d33c9a4e82b0edb096db9 320 Pfam PF01629 Domain of unknown function DUF22 181 276 8.0E-36 T 31-10-2018 IPR002572 Domain of unknown function DUF22 AF_0178 39c88bc97c9d33c9a4e82b0edb096db9 320 Pfam PF01629 Domain of unknown function DUF22 40 144 2.1E-40 T 31-10-2018 IPR002572 Domain of unknown function DUF22 AF_2276 67f77f6d9533e57d077f7fac106b0d5b 295 Pfam PF07670 Nucleoside recognition 17 110 5.5E-8 T 31-10-2018 IPR011642 Nucleoside transporter/FeoB GTPase, Gate domain Reactome: R-HSA-83936 AF_1086 89500f8e556393b4eae03c11f705377e 69 SUPERFAMILY SSF88723 1 67 5.61E-6 T 31-10-2018 IPR029060 PIN-like domain superfamily AF_0153 d22a64da6343127d0a17812673de5546 202 Pfam PF06168 Protein of unknown function (DUF981) 1 186 1.1E-53 T 31-10-2018 IPR009324 Protein of unknown function DUF981 AF_1870 d62824bf4e89894c6b8de0d1d268d3e5 116 TIGRFAM TIGR01878 cas_Csa5: CRISPR type I-A/APERN-associated protein Csa5 18 109 4.8E-20 T 31-10-2018 IPR010157 CRISPR type I-A/APERN-associated protein Csa5 AF_0630 207ca520ecc5e230275a62406e07e2f7 197 Pfam PF01988 VIT family 27 96 9.5E-9 T 31-10-2018 IPR008217 Ccc1 family AF_0630 207ca520ecc5e230275a62406e07e2f7 197 Pfam PF01988 VIT family 81 188 2.7E-11 T 31-10-2018 IPR008217 Ccc1 family AF_0612 f140ccdf6172c084c41786d5919d64d9 128 TIGRFAM TIGR03698 clan_AA_DTGF: clan AA aspartic protease, AF_0612 family 8 122 3.0E-35 T 31-10-2018 IPR022274 Peptidase aspartic, AF0612 AF_0426 4764932cfb0233d5d577ab61f67de7a8 312 Pfam PF04467 Protein of unknown function (DUF483) 110 247 4.4E-39 T 31-10-2018 IPR007556 Protein of unknown function DUF483 AF_1654 4d35bff714535406c5d4556240aded88 329 Pfam PF17231 Family of unknown function (DUF5305) 130 325 3.7E-25 T 31-10-2018 IPR035185 Protein of unknown function DUF5305 AF_1660 b827b4c7660726c82f3dac519dcca0f9 202 Pfam PF12389 Camelysin metallo-endopeptidase 5 72 1.0E-6 T 31-10-2018 IPR022121 Peptidase M73, camelysin AF_1660 b827b4c7660726c82f3dac519dcca0f9 202 TIGRFAM TIGR04088 cognate_SipW: SipW-cognate class signal peptide 11 45 3.0E-10 T 31-10-2018 IPR023833 Signal peptide, camelysin AF_0119 56d77808501ae28ceeeb775e66f8048a 442 Pfam PF01629 Domain of unknown function DUF22 290 395 4.9E-40 T 31-10-2018 IPR002572 Domain of unknown function DUF22 AF_0119 56d77808501ae28ceeeb775e66f8048a 442 Pfam PF01629 Domain of unknown function DUF22 5 113 6.3E-39 T 31-10-2018 IPR002572 Domain of unknown function DUF22 AF_0119 56d77808501ae28ceeeb775e66f8048a 442 Pfam PF01629 Domain of unknown function DUF22 153 258 3.9E-41 T 31-10-2018 IPR002572 Domain of unknown function DUF22 AF_1571 f28a737d6a84cfb8a3a28371df610389 340 Pfam PF00882 Zinc dependent phospholipase C 40 200 4.2E-11 T 31-10-2018 IPR029002 Phospholipase C/D Reactome: R-HSA-163125 AF_1194 bd96bb5540b88761ad9ae91800c42bb8 144 Pfam PF09999 Uncharacterized protein conserved in archaea (DUF2240) 1 138 1.8E-35 T 31-10-2018 IPR018716 Protein of unknown function DUF2240 AF_0503 81bd8f09ee8172f0c4b924f9a6f1aa4a 145 SUPERFAMILY SSF48695 77 125 8.72E-7 T 31-10-2018 IPR036280 Multiheme cytochrome superfamily AF_0524 244388d6fbb29d41359c99c6855838dc 225 Pfam PF07786 Protein of unknown function (DUF1624) 2 207 3.9E-58 T 31-10-2018 IPR012429 Domain of unknown function DUF1624 Reactome: R-HSA-2024096|Reactome: R-HSA-2206291|Reactome: R-HSA-6798695 AF_2020 b853dfe82b5cdd17c88ae60598158abe 191 ProDom PD695862 AF1173 AF0136 AF2020 1 185 1.0E-89 T 31-10-2018 AF_0829 79d20191622823044dfd9e44181490a1 183 SUPERFAMILY SSF48371 11 149 2.24E-6 T 31-10-2018 IPR016024 Armadillo-type fold AF_1346 b65b83e5a0d57e2cdc860c162d088aae 288 Pfam PF04894 Archaeal Nre, N-terminal 14 276 4.4E-95 T 31-10-2018 IPR006978 Archaeal Nre, N-terminal AF_1393 1c873f370d34cf6a13ff2e135c207a9c 449 Pfam PF02653 Branched-chain amino acid transport system / permease component 110 423 1.9E-71 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AF_0825 7e87d2ab54d12653716a0106f2d9ac72 297 Pfam PF02653 Branched-chain amino acid transport system / permease component 12 282 1.1E-49 T 31-10-2018 IPR001851 ABC transporter, permease GO:0016020|GO:0022857|GO:0055085 AF_0136 6add98cdfff7abc141da98f07df03f79 185 ProDom PD695862 AF1173 AF0136 AF2020 1 182 1.0E-94 T 31-10-2018 AF_2262 e41a67b2d6057e510f2eef1a6d5e4df2 62 ProDom PD053081 COIL MM0410 AF2262 COILED 7 59 3.0E-15 T 31-10-2018