locus-tag	class	description
AFULGI_00000020	ENOG4108IPW	abc transporter atp-binding protein
AFULGI_00000040	ENOG4108Q52	Methyltransferase cognate corrinoid protein
AFULGI_00000070	ENOG4108QZ0	Tetrahydromethanopterin S-methyltransferase (EC 2.1.1.86)
AFULGI_00000090	ENOG4108Q52	Methyltransferase cognate corrinoid protein
AFULGI_00000150	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AFULGI_00000160	ENOG4105CHU	acetyl-coa acetyltransferase
AFULGI_00000180	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AFULGI_00000190	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AFULGI_00000210	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
AFULGI_00000250	ENOG41067KJ	GYD family
AFULGI_00000310	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AFULGI_00000330	ENOG4105EIP	mannose-6-phosphate isomerase
AFULGI_00000440	ENOG4105DZH	s-adenosylmethionine synthetase (EC 2.5.1.6)
AFULGI_00000450	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AFULGI_00000540	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AFULGI_00000550	ENOG41080XQ	Signal transduction protein with cbs domains
AFULGI_00000670	ENOG4105ZVY	2-oxoisovalerate dehydrogenase, E1 component beta subunit
AFULGI_00000690	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
AFULGI_00000710	ENOG4108RC0	Electron transport protein
AFULGI_00000750	ENOG4105C8Y	Acetylornithine aminotransferase
AFULGI_00000820	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
AFULGI_00000870	ENOG4105CEY	Amp-dependent synthetase and ligase
AFULGI_00000900	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AFULGI_00000910	ENOG4105E0C	molybdate abc transporter
AFULGI_00000920	ENOG41066FR	extracellular solute-binding protein
AFULGI_00001030	ENOG4105CXT	aspartate transcarbamylase
AFULGI_00001040	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
AFULGI_00001050	ENOG41061GT	Aldolase
AFULGI_00001070	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AFULGI_00001090	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AFULGI_00001120	ENOG4105CQP	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
AFULGI_00001260	ENOG4105Y7X	Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA. Acts in DNA repair (By similarity)
AFULGI_00001270	ENOG4105DGU	Histone deacetylase
AFULGI_00001380	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AFULGI_00001520	ENOG4107SJW	iron permease, FTR1
AFULGI_00001540	ENOG4108R3D	Electron transport complex
AFULGI_00001550	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AFULGI_00001570	ENOG4105DB1	molybdopterin oxidoreductase
AFULGI_00001590	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AFULGI_00001630	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
AFULGI_00001650	ENOG41084T3	4fe-4S ferredoxin iron-sulfur binding domain-containing protein
AFULGI_00001680	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
AFULGI_00001690	ENOG4107QI6	Cysteine desulfurase
AFULGI_00001710	ENOG41082K8	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Interacts with IscS and stimulates its activity. Then, accepts a sulfur from IscS and transfers it in turn to TusD (By similarity)
AFULGI_00001810	ENOG4105CEY	Amp-dependent synthetase and ligase
AFULGI_00001820	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AFULGI_00001830	ENOG4105DXM	phenylacetic acid degradation protein
AFULGI_00001850	ENOG4108IQE	Amp-dependent synthetase and ligase
AFULGI_00001900	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AFULGI_00001940	ENOG4105GR3	Histidine kinase
AFULGI_00001950	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
AFULGI_00001970	ENOG4105CJW	magnesium transporter
AFULGI_00001980	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
AFULGI_00002020	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AFULGI_00002050	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AFULGI_00002060	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
AFULGI_00002070	ENOG4108IV0	ABC, transporter
AFULGI_00002080	ENOG4105C0Z	ABC transporter
AFULGI_00002100	ENOG4105C32	Amino acid ABC transporter (Permease)
AFULGI_00002130	ENOG4105CQC	Prephenate dehydratase
AFULGI_00002150	ENOG4106M32	3-dehydroquinate synthase
AFULGI_00002160	ENOG41061GT	Aldolase
AFULGI_00002180	ENOG4105E5Q	amino acid AbC transporter
AFULGI_00002190	ENOG4105D4M	Lactamase_B
AFULGI_00002200	ENOG4105D0M	Protease HtpX homolog
AFULGI_00002230	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
AFULGI_00002240	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
AFULGI_00002270	ENOG4108R96	Methyltransferase, YaeB family
AFULGI_00002280	ENOG4107QQ4	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans (By similarity)
AFULGI_00002320	ENOG4105CE1	Ferrous iron transport protein b
AFULGI_00002380	ENOG4105W49	UPF0434 protein
AFULGI_00002390	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
AFULGI_00002400	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AFULGI_00002410	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AFULGI_00002510	ENOG4105CX6	glutaminyL-tRNA synthetase
AFULGI_00002530	ENOG4105CEY	Amp-dependent synthetase and ligase
AFULGI_00002550	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AFULGI_00002630	ENOG4105D3R	alkyl hydroperoxide reductase
AFULGI_00002690	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AFULGI_00002710	ENOG4108K7V	UPF0284 protein
AFULGI_00002730	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
AFULGI_00002770	ENOG4105CHU	acetyl-coa acetyltransferase
AFULGI_00002790	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AFULGI_00002810	ENOG4105C10	Electron transfer flavoprotein
AFULGI_00002820	ENOG4107T1U	Catalyzes the synthesis of activated sulfate (By similarity)
AFULGI_00002840	ENOG4105EY8	ABC transporter
AFULGI_00002980	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AFULGI_00003190	ENOG4107ZIM	Dtdp-4-dehydrorhamnose 3,5-epimerase
AFULGI_00003200	ENOG4105DBZ	Dtdp-4-dehydrorhamnose reductase
AFULGI_00003210	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
AFULGI_00003230	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
AFULGI_00003260	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AFULGI_00003270	ENOG4106N3V	dolichyl-phosphate beta-D-mannosyltransferase (EC 2.4.1.83)
AFULGI_00003380	ENOG4105C0A	alcohol dehydrogenase
AFULGI_00003430	ENOG4108YZ8	Superoxide reductase
AFULGI_00003570	ENOG4108RVA	ribokinase
AFULGI_00003590	ENOG4105CB5	ATP-dependent DNA helicase recG
AFULGI_00003650	ENOG4108IUQ	atp-dependent protease
AFULGI_00003670	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AFULGI_00003700	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AFULGI_00003710	ENOG4105GRF	N-glycosylase DNA lyase
AFULGI_00003720	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
AFULGI_00003760	ENOG4105EYX	Acetyl-CoA decarbonylase synthase complex subunit gamma
AFULGI_00003770	ENOG4106HYN	CO dehydrogenase acetyl-CoA synthase delta subunit
AFULGI_00003780	ENOG41080XS	Cobyrinic acid ac-diamide synthase
AFULGI_00003790	ENOG4105E8X	CO dehydrogenase acetyl-CoA synthase complex beta subunit
AFULGI_00003870	ENOG4107QV3	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AFULGI_00003890	ENOG4105DVY	radical SAM domain protein
AFULGI_00003910	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
AFULGI_00004040	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AFULGI_00004140	ENOG4105CHM	Aminotransferase
AFULGI_00004150	ENOG4105BZU	Histidine kinase
AFULGI_00004160	ENOG4105C8N	cysteinyl-tRNA synthetase
AFULGI_00004260	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AFULGI_00004270	ENOG4105CY1	sulfite reductase, dissimilatory-type alpha subunit
AFULGI_00004280	ENOG4105PJW	Sulfite reductase dissimilatory-type beta subunit
AFULGI_00004320	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AFULGI_00004350	ENOG4105EHG	Permease protein
AFULGI_00004380	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AFULGI_00004390	ENOG4105E39	Enoyl-CoA hydratase
AFULGI_00004400	ENOG4105C1G	acyl-Coa dehydrogenase
AFULGI_00004420	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
AFULGI_00004440	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
AFULGI_00004450	ENOG4107WPW	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
AFULGI_00004460	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
AFULGI_00004540	ENOG4105BZU	Histidine kinase
AFULGI_00004550	ENOG4107YTP	response regulator receiver protein
AFULGI_00004560	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AFULGI_00004610	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AFULGI_00004640	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
AFULGI_00004650	ENOG4105EYF	MMPL domain protein
AFULGI_00004720	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AFULGI_00004760	ENOG4105DQU	oxidoreductase, subunit beta
AFULGI_00004770	ENOG4105DI2	Pyruvate flavodoxin ferredoxin oxidoreductase domain protein
AFULGI_00004810	ENOG4105C59	p-type ATPase
AFULGI_00004830	ENOG4105D6J	arsenicaL-resistance protein
AFULGI_00004850	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AFULGI_00004860	ENOG4105E8R	UPF0173 metal-dependent hydrolase
AFULGI_00004900	ENOG4105CY0	Metallo-Beta-Lactamase
AFULGI_00004920	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
AFULGI_00004950	ENOG4105CUJ	penicillin amidase
AFULGI_00005000	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AFULGI_00005010	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AFULGI_00005020	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
AFULGI_00005060	ENOG4105CQ2	DNA polymerase
AFULGI_00005090	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
AFULGI_00005160	ENOG4105DF6	Fe-S oxidoreductase
AFULGI_00005180	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
AFULGI_00005190	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
AFULGI_00005220	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AFULGI_00005290	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
AFULGI_00005310	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
AFULGI_00005360	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AFULGI_00005370	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
AFULGI_00005390	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
AFULGI_00005400	ENOG4105D06	uba thif-type nad fad binding protein
AFULGI_00005440	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AFULGI_00005470	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
AFULGI_00005510	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AFULGI_00005530	ENOG4107QQM	Cysteine-rich domain
AFULGI_00005570	ENOG4107QQM	Cysteine-rich domain
AFULGI_00005580	ENOG4105C22	threonyL-tRNA synthetase
AFULGI_00005600	ENOG41080U2	Amidohydrolase family
AFULGI_00005610	ENOG4108IYI	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine (By similarity)
AFULGI_00005630	ENOG4105D06	uba thif-type nad fad binding protein
AFULGI_00005660	ENOG4107XUC	SirA family
AFULGI_00005670	ENOG4107SA8	fad-dependent pyridine nucleotide-disulfide oxidoreductase
AFULGI_00005690	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AFULGI_00005780	ENOG4107QI6	Cysteine desulfurase
AFULGI_00005790	ENOG4107RIU	May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins (By similarity)
AFULGI_00005820	ENOG4105CEY	Amp-dependent synthetase and ligase
AFULGI_00005870	ENOG4107DA6	Transcriptional regulator
AFULGI_00005980	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
AFULGI_00006040	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AFULGI_00006050	ENOG4105C79	DNA protecting protein DprA
AFULGI_00006080	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
AFULGI_00006120	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
AFULGI_00006170	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AFULGI_00006180	ENOG4107RFY	SbcCD D subunit
AFULGI_00006270	ENOG410695F	Crispr-associated protein, Csm1 family
AFULGI_00006290	ENOG4108W8W	CRISPR-associated RAMP protein, Csm3 family
AFULGI_00006380	ENOG4106FRU	abrb family transcriptional regulator
AFULGI_00006460	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AFULGI_00006510	ENOG4105C5X	domain protein
AFULGI_00006560	ENOG4105CGK	Exodeoxyribonuclease III
AFULGI_00006570	ENOG4105CKK	Glycosyl transferase, family 2
AFULGI_00006590	ENOG4105EW9	transcriptional regulator AsnC family
AFULGI_00006630	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AFULGI_00006640	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
AFULGI_00006650	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
AFULGI_00006670	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AFULGI_00006710	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
AFULGI_00006810	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
AFULGI_00006840	ENOG4107T8Q	Glycosyl transferase (Group 1
AFULGI_00006960	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AFULGI_00007010	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
AFULGI_00007020	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AFULGI_00007030	ENOG4107QIM	DNA ligase
AFULGI_00007080	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
AFULGI_00007090	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AFULGI_00007130	ENOG41083MR	nifu domain-containing protein
AFULGI_00007140	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
AFULGI_00007200	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
AFULGI_00007210	ENOG4105D7T	ABC transporter
AFULGI_00007260	ENOG4108HMX	isocitrate dehydrogenase (NADP)
AFULGI_00007340	ENOG4107S7U	Sulfide dehydrogenase
AFULGI_00007400	ENOG4108ZPQ	MazG nucleotide pyrophosphohydrolase
AFULGI_00007420	ENOG4107EFR	Flavocytochrome c
AFULGI_00007430	ENOG4105EWK	phytoene
AFULGI_00007450	ENOG4105D9P	serine threonine protein kinase
AFULGI_00007500	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
AFULGI_00007510	ENOG4105C1G	acyl-Coa dehydrogenase
AFULGI_00007520	ENOG4105CEY	Amp-dependent synthetase and ligase
AFULGI_00007560	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
AFULGI_00007570	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AFULGI_00007660	ENOG4105E39	Enoyl-CoA hydratase
AFULGI_00007680	ENOG4105CEY	Amp-dependent synthetase and ligase
AFULGI_00007720	ENOG4105D26	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway (By similarity)
AFULGI_00007780	ENOG4107QMS	site-determining protein
AFULGI_00007840	ENOG4105IQJ	Involved in biosynthesis of the thiamine precursor thiazole (By similarity)
AFULGI_00007890	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AFULGI_00007920	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
AFULGI_00007950	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AFULGI_00007990	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AFULGI_00008030	ENOG4105EE8	May catalyze the methylation of C-1 in cobalt-precorrin- 5 and the subsequent extrusion of acetic acid from the resulting intermediate to form cobalt-precorrin-6A (By similarity)
AFULGI_00008040	ENOG4105E4R	Precorrin-3B C17-methyltransferase
AFULGI_00008060	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
AFULGI_00008080	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
AFULGI_00008110	ENOG4108JJB	ABC transporter
AFULGI_00008130	ENOG4105CG2	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 (By similarity)
AFULGI_00008180	ENOG4106C07	ThiamineS Protein
AFULGI_00008220	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
AFULGI_00008240	ENOG4105MRR	Transcriptional regulator (By similarity)
AFULGI_00008260	ENOG4105CS7	Catalyzes the conversion of dihydroorotate to orotate
AFULGI_00008280	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
AFULGI_00008310	ENOG4105DQU	oxidoreductase, subunit beta
AFULGI_00008360	ENOG4105DF6	Fe-S oxidoreductase
AFULGI_00008370	ENOG4105E2M	Manganese-dependent inorganic pyrophosphatase
AFULGI_00008480	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
AFULGI_00008490	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
AFULGI_00008510	ENOG4105BZU	Histidine kinase
AFULGI_00008560	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
AFULGI_00008610	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AFULGI_00008640	ENOG4105X8U	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation (By similarity)
AFULGI_00008660	ENOG4105D7N	magnesium and cobalt transport protein CorA
AFULGI_00008700	ENOG4108PCN	EamA-like transporter family
AFULGI_00008790	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
AFULGI_00008800	ENOG4105DKF	Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) (By similarity)
AFULGI_00008830	ENOG4105CU5	Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine (By similarity)
AFULGI_00008910	ENOG4105DAA	L-lactate
AFULGI_00008930	ENOG4105CQB	FAD linked oxidase domain protein
AFULGI_00008970	ENOG4107QR9	Iron-sulfur cluster binding protein
AFULGI_00009010	ENOG4108K3F	N(2),N(2)-dimethylguanosine tRNA methyltransferase
AFULGI_00009040	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
AFULGI_00009050	ENOG4105C0S	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (By similarity)
AFULGI_00009080	ENOG4108IV0	ABC, transporter
AFULGI_00009090	ENOG4105C0Z	ABC transporter
AFULGI_00009110	ENOG4105C32	Amino acid ABC transporter (Permease)
AFULGI_00009130	ENOG4105CP9	extracellular ligand-binding receptor
AFULGI_00009160	ENOG4105VCQ	rubredoxin
AFULGI_00009170	ENOG4108RAC	Rubrerythrin
AFULGI_00009190	ENOG4105MAX	Superoxide reductase
AFULGI_00009220	ENOG4105C1A	potassium transporter peripheral membrane
AFULGI_00009230	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
AFULGI_00009240	ENOG4105CEY	Amp-dependent synthetase and ligase
AFULGI_00009250	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
AFULGI_00009290	ENOG4105C1G	acyl-Coa dehydrogenase
AFULGI_00009310	ENOG4108IJ8	ABC transporter
AFULGI_00009320	ENOG41080XP	Cbs domain
AFULGI_00009350	ENOG4108DFU	YjeF-related protein N-terminus
AFULGI_00009360	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
AFULGI_00009370	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AFULGI_00009390	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
AFULGI_00009490	ENOG4105D3C	The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters (By similarity)
AFULGI_00009530	ENOG4105CQB	FAD linked oxidase domain protein
AFULGI_00009540	ENOG4105K8R	UPF0145 protein
AFULGI_00009560	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
AFULGI_00009670	ENOG4105VCQ	rubredoxin
AFULGI_00009690	ENOG4108TAG	Histidine kinase
AFULGI_00009700	ENOG4105HDK	L-asparaginase
AFULGI_00009710	ENOG4105CH7	arginosuccinase
AFULGI_00009750	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AFULGI_00009760	ENOG4108JQ9	ABC transporter
AFULGI_00009770	ENOG4105UIB	(ABC) transporter
AFULGI_00009820	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AFULGI_00009870	ENOG4108K16	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AFULGI_00009900	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
AFULGI_00009930	ENOG4105DJB	Major Facilitator Superfamily
AFULGI_00009950	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
AFULGI_00009960	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
AFULGI_00010000	ENOG4108ZJT	translation initiation factor, Sui1
AFULGI_00010020	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
AFULGI_00010030	ENOG4105EIH	LPPG Fo 2-phospho-L-lactate transferase
AFULGI_00010060	ENOG4105C5S	asparaginyl-tRNA synthetase
AFULGI_00010170	ENOG4107XGZ	Hydrolase
AFULGI_00010180	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
AFULGI_00010190	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AFULGI_00010200	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
AFULGI_00010230	ENOG4105CM2	brancheD-chain amino acid aminotransferase
AFULGI_00010250	ENOG4105D6E	homoserine dehydrogenase
AFULGI_00010270	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
AFULGI_00010280	ENOG4108Z10	Involved in the binding of tRNA to the ribosomes (By similarity)
AFULGI_00010290	ENOG4105IES	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA (By similarity)
AFULGI_00010320	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
AFULGI_00010330	ENOG4105E66	phosphoriboisomerase A
AFULGI_00010390	ENOG4105C5F	glutamine synthetase
AFULGI_00010400	ENOG4105QAX	Iron-sulfur
AFULGI_00010410	ENOG4108IFG	nitrite reductase, (NAD(P)H)
AFULGI_00010420	ENOG4105EYU	Glutamine amido-transferase
AFULGI_00010430	ENOG4105CBC	glutamate synthase
AFULGI_00010470	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
AFULGI_00010480	ENOG4105DIK	(ABC) transporter
AFULGI_00010490	ENOG4108IUZ	ABC transporter
AFULGI_00010500	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
AFULGI_00010530	ENOG4105E39	Enoyl-CoA hydratase
AFULGI_00010590	ENOG4107QN1	sodium solute
AFULGI_00010620	ENOG41083X2	DNA polymerase III, epsilon subunit
AFULGI_00010630	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AFULGI_00010640	ENOG410846T	CoA-transferase family III
AFULGI_00010650	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AFULGI_00010670	ENOG4105BZU	Histidine kinase
AFULGI_00010700	ENOG4105R40	Glycine betaine carnitine choline
AFULGI_00010710	ENOG4108IJ8	ABC transporter
AFULGI_00010720	ENOG4107SI7	Substrate-binding region of abc-type glycine betaine transport system
AFULGI_00010750	ENOG4108IUW	ABC transporter
AFULGI_00010760	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
AFULGI_00010770	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
AFULGI_00010790	ENOG4108IV0	ABC, transporter
AFULGI_00010800	ENOG4105C0Z	ABC transporter
AFULGI_00010820	ENOG4105C32	Amino acid ABC transporter (Permease)
AFULGI_00010910	ENOG4105D6T	Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine (By similarity)
AFULGI_00010990	ENOG4107QWP	ABC-2 type transporter
AFULGI_00011000	ENOG4105CJ1	ABC, transporter
AFULGI_00011050	ENOG4108NGU	Transcriptional regulator
AFULGI_00011100	ENOG4105C01	Dihydroxy-acid dehydratase
AFULGI_00011130	ENOG4107RBB	ABC transporter, permease
AFULGI_00011140	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AFULGI_00011170	ENOG4105CJ1	ABC, transporter
AFULGI_00011180	ENOG4105F4R	Transcriptional regulator mode
AFULGI_00011190	ENOG4107QZT	geranylgeranyl reductase
AFULGI_00011200	ENOG4106K5Q	Modifies the topological state of DNA by introducing positive supercoils in an ATP-dependent process. It cleaves transiently a single DNA strand and remains covalently bound to the 5' DNA end through a tyrosine residue. May be involved in rewinding the DNA strands in the regions of the chromosome that have opened up to allow transcription or replication (By similarity)
AFULGI_00011210	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AFULGI_00011220	ENOG4105C1G	acyl-Coa dehydrogenase
AFULGI_00011240	ENOG4105CHU	acetyl-coa acetyltransferase
AFULGI_00011250	ENOG4105CEY	Amp-dependent synthetase and ligase
AFULGI_00011280	ENOG4105C3X	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP (By similarity)
AFULGI_00011300	ENOG4105C8Q	Methyl-accepting chemotaxis
AFULGI_00011330	ENOG4105BZU	Histidine kinase
AFULGI_00011340	ENOG4108Z4W	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis (By similarity)
AFULGI_00011350	ENOG4107PHP	CheC --inhibitor of MCP methylation
AFULGI_00011360	ENOG4105CBS	Chea signal transduction histidine kinase
AFULGI_00011370	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AFULGI_00011380	ENOG4107YTP	response regulator receiver protein
AFULGI_00011400	ENOG4108V3W	Chemotaxis protein, CheW
AFULGI_00011620	ENOG4107YTP	response regulator receiver protein
AFULGI_00011630	ENOG4105FDK	ABC transporter
AFULGI_00011680	ENOG4108IA2	Sodium pantothenate symporter
AFULGI_00011700	ENOG4105DZS	Phenylacetate-CoA ligase
AFULGI_00012090	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
AFULGI_00012140	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
AFULGI_00012190	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AFULGI_00012230	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
AFULGI_00012260	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
AFULGI_00012310	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
AFULGI_00012320	ENOG4105CE9	30S ribosomal protein S2
AFULGI_00012410	ENOG4107Z36	nucleotidyl transferase
AFULGI_00012440	ENOG4105CYC	Transferase
AFULGI_00012450	ENOG4105BZA	Phosphoglycerate kinase
AFULGI_00012460	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
AFULGI_00012470	ENOG4105FKN	transcriptional regulator, AsnC family
AFULGI_00012480	ENOG4107QRT	dEAD DEAH box helicase
AFULGI_00012580	ENOG4107QNG	Phosphoribosylglycinamide synthetase
AFULGI_00012630	ENOG41089ID	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
AFULGI_00012650	ENOG4108JIQ	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit (By similarity)
AFULGI_00012660	ENOG4108JIP	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit (By similarity)
AFULGI_00012680	ENOG4105VKD	bioY protein
AFULGI_00012690	ENOG4108JJB	ABC transporter
AFULGI_00012740	ENOG4105C1G	acyl-Coa dehydrogenase
AFULGI_00012760	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AFULGI_00012810	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
AFULGI_00012840	ENOG4105BZU	Histidine kinase
AFULGI_00012860	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
AFULGI_00012870	ENOG4107T0D	ABC, transporter
AFULGI_00012890	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AFULGI_00012900	ENOG4108IPT	Naphthoate synthase
AFULGI_00012910	ENOG4105CD5	CoA-binding domain protein
AFULGI_00012940	ENOG4105D1H	recombination factor protein RarA
AFULGI_00012960	ENOG4105CHU	acetyl-coa acetyltransferase
AFULGI_00013010	ENOG4105QAX	Iron-sulfur
AFULGI_00013050	ENOG4105F35	Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine (By similarity)
AFULGI_00013060	ENOG4105CHR	reductase
AFULGI_00013090	ENOG4105DE9	3-keto-5-aminohexanoate cleavage enzyme
AFULGI_00013100	ENOG4105CD5	CoA-binding domain protein
AFULGI_00013140	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
AFULGI_00013150	ENOG4105DK7	lysyl-tRNA synthetase
AFULGI_00013180	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
AFULGI_00013210	ENOG4107QN1	sodium solute
AFULGI_00013230	ENOG4105E4Y	Endoribonuclease that initiates mRNA decay (By similarity)
AFULGI_00013280	ENOG4105EYF	MMPL domain protein
AFULGI_00013300	ENOG4108NGU	Transcriptional regulator
AFULGI_00013380	ENOG4108JEB	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AFULGI_00013390	ENOG4105CDM	Glutamate-1-semialdehyde aminotransferase
AFULGI_00013400	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
AFULGI_00013410	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
AFULGI_00013430	ENOG4107S91	Sodium hydrogen exchanger
AFULGI_00013450	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
AFULGI_00013460	ENOG4108UQV	Membrane
AFULGI_00013500	ENOG4107QSA	Oxaloacetate decarboxylase
AFULGI_00013530	ENOG4105DBV	ornithine carbamoyltransferase
AFULGI_00013540	ENOG4105CMP	catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR (By similarity)
AFULGI_00013570	ENOG4108IJ8	ABC transporter
AFULGI_00013580	ENOG4108DGI	Phosphoribosylformylglycinamidine synthase I
AFULGI_00013610	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
AFULGI_00013640	ENOG4107WCI	zn-dependent hydrolase of the beta-lactamase fold-like protein
AFULGI_00013700	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AFULGI_00013740	ENOG4105CTK	cobaltochelatase, cobn subunit
AFULGI_00013770	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
AFULGI_00013790	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
AFULGI_00013800	ENOG4105C8V	SAICAR synthetase
AFULGI_00013810	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AFULGI_00013820	ENOG4105CU6	carbamoyl-phosphate synthetase ammonia chain
AFULGI_00013830	ENOG4105DTC	1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (air) carboxylase
AFULGI_00013850	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
AFULGI_00013880	ENOG4105CAS	nag kinase
AFULGI_00013900	ENOG4108Z0Z	intracellular protease Pfpi family
AFULGI_00013940	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AFULGI_00013960	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
AFULGI_00013980	ENOG4105D5P	Methylmalonyl-coA mutase
AFULGI_00014030	ENOG4105C1G	acyl-Coa dehydrogenase
AFULGI_00014070	ENOG4105MYT	Heat shock protein
AFULGI_00014080	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AFULGI_00014120	ENOG4105DA5	(ABC) transporter
AFULGI_00014150	ENOG4105CP7	Triose-phosphate isomerase
AFULGI_00014160	ENOG4108P4C	Formaldehyde-activating enzyme
AFULGI_00014190	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
AFULGI_00014210	ENOG4105CSA	Coproporphyrinogen iii oxidase
AFULGI_00014250	ENOG4105C04	l-carnitine dehydratase bile acid-inducible protein F
AFULGI_00014310	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
AFULGI_00014320	ENOG4107R56	PP-loop domain protein
AFULGI_00014370	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
AFULGI_00014390	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
AFULGI_00014470	ENOG4105DH2	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group (By similarity)
AFULGI_00014500	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AFULGI_00014510	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
AFULGI_00014520	ENOG4105BZN	citrate synthase
AFULGI_00014550	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AFULGI_00014560	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AFULGI_00014600	ENOG4105VCQ	rubredoxin
AFULGI_00014610	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AFULGI_00014650	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
AFULGI_00014670	ENOG4107QMV	Part of the ABC transporter complex PstSACB involved in phosphate import (By similarity)
AFULGI_00014680	ENOG4105C8U	phosphate abc transporter
AFULGI_00014690	ENOG4105E2Z	phosphate ABC transporter (Permease
AFULGI_00014700	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
AFULGI_00014750	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AFULGI_00014790	ENOG4105WMM	Probably plays a role in a hydrogenase nickel cofactor insertion step (By similarity)
AFULGI_00014800	ENOG4107RSS	Hydrogenase accessory protein HypB
AFULGI_00014820	ENOG4105CQS	hydrogenase expression formation protein HypD
AFULGI_00014920	ENOG4105DPX	Hydrogenase, large subunit
AFULGI_00014930	ENOG4105E3S	small subunit
AFULGI_00014980	ENOG4106FRU	abrb family transcriptional regulator
AFULGI_00015000	ENOG4108IV0	ABC, transporter
AFULGI_00015010	ENOG4105C0Z	ABC transporter
AFULGI_00015080	ENOG4105JKQ	Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC (By similarity)
AFULGI_00015090	ENOG4105EWU	Squalene--hopene cyclase
AFULGI_00015100	ENOG4105CNE	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane (By similarity)
AFULGI_00015130	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
AFULGI_00015140	ENOG4105EHG	Permease protein
AFULGI_00015210	ENOG4107QMH	DNA methylase
AFULGI_00015280	ENOG4105FIK	Inherit from COG: dihydropteroate synthase
AFULGI_00015310	ENOG4105C5R	Aminotransferase
AFULGI_00015320	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
AFULGI_00015340	ENOG4107QX8	SPFH domain, Band 7 family protein
AFULGI_00015350	ENOG4105DJZ	UPF0182 protein
AFULGI_00015370	ENOG4105DCI	Phosphohydrolase
AFULGI_00015390	ENOG4105E3H	phosphoglycerate mutase
AFULGI_00015400	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
AFULGI_00015470	ENOG4108UUC	Protein of unknown function DUF99
AFULGI_00015490	ENOG4105CKX	Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP
AFULGI_00015540	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AFULGI_00015560	ENOG4107NFR	Fructose-1,6-bisphosphatase
AFULGI_00015570	ENOG4105EHU	Circadian clock protein KaiC
AFULGI_00015620	ENOG4105F7P	transcriptional regulator AsnC family
AFULGI_00015650	ENOG4105F1A	Pyruvate formate-lyase
AFULGI_00015660	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AFULGI_00015670	ENOG4105BZU	Histidine kinase
AFULGI_00015680	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
AFULGI_00015710	ENOG4108JA2	transcriptioN-repair coupling factor
AFULGI_00015950	ENOG4105EHU	Circadian clock protein KaiC
AFULGI_00016160	ENOG41071TK	Uncharacterised protein family (UPF0150)
AFULGI_00016890	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
AFULGI_00016900	ENOG4107RFY	SbcCD D subunit
AFULGI_00017120	ENOG4108FPN	Integrase
AFULGI_00017210	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AFULGI_00017220	ENOG4108EE5	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AFULGI_00017240	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
AFULGI_00017270	ENOG4105KAV	tspo and mbr like protein
AFULGI_00017280	ENOG41090KQ	Glyoxalase Bleomycin resistance protein (Dioxygenase
AFULGI_00017340	ENOG4105BZU	Histidine kinase
AFULGI_00017360	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
AFULGI_00017370	ENOG4108MYP	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
AFULGI_00017420	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
AFULGI_00017430	ENOG4108VZM	50s ribosomal protein L10
AFULGI_00017580	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
AFULGI_00017620	ENOG4105CEY	Amp-dependent synthetase and ligase
AFULGI_00017630	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AFULGI_00017640	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
AFULGI_00017690	ENOG4105PW4	Sugar fermentation stimulation protein homolog
AFULGI_00017730	ENOG4105CNW	domain protein
AFULGI_00017760	ENOG4105E0I	Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP) (By similarity)
AFULGI_00017910	ENOG41081E8	Alpha beta hydrolase
AFULGI_00017920	ENOG4105CRW	Short chain fatty acid transporter
AFULGI_00017930	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AFULGI_00017940	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AFULGI_00017960	ENOG4105VUN	Transcriptional regulator
AFULGI_00018070	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
AFULGI_00018080	ENOG4105C3M	thioredoxin reductase
AFULGI_00018090	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
AFULGI_00018320	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
AFULGI_00018380	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
AFULGI_00018440	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
AFULGI_00018490	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
AFULGI_00018500	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
AFULGI_00018510	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
AFULGI_00018520	ENOG4105DDQ	anthranilate synthase
AFULGI_00018530	ENOG4105CRQ	synthase (Component I)
AFULGI_00018550	ENOG4105DK0	Indole-3-glycerol phosphate synthase
AFULGI_00018570	ENOG4105D38	putrescine abc transporter
AFULGI_00018580	ENOG4105F38	ABC transporter, permease
AFULGI_00018590	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
AFULGI_00018600	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
AFULGI_00018610	ENOG4105X3E	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine (By similarity)
AFULGI_00018620	ENOG4108JVH	Protein of unknown function DUF43
AFULGI_00018630	ENOG4105C85	amino acid
AFULGI_00018690	ENOG4105D63	family UPF0324
AFULGI_00018720	ENOG4105HMI	Membrane
AFULGI_00018740	ENOG4105CHM	Aminotransferase
AFULGI_00018750	ENOG4105M00	molybdopterin converting factor, subunit 1
AFULGI_00018810	ENOG4108JEJ	Pyruvoyl-dependent arginine decarboxylase
AFULGI_00018850	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AFULGI_00018880	ENOG4105DT1	RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate
AFULGI_00018890	ENOG4105BZU	Histidine kinase
AFULGI_00018900	ENOG4108RAC	Rubrerythrin
AFULGI_00018910	ENOG4105E39	Enoyl-CoA hydratase
AFULGI_00018920	ENOG4105CUT	histidyl-tRNA synthetase
AFULGI_00018930	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
AFULGI_00018950	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
AFULGI_00019020	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AFULGI_00019020	ENOG4105RX7	peptidase S8 and S53, subtilisin, kexin, sedolisin
AFULGI_00019200	ENOG4105DZS	Phenylacetate-CoA ligase
AFULGI_00019230	ENOG4108MDK	Dehydrogenase
AFULGI_00019250	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
AFULGI_00019260	ENOG4106NZV	Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs (By similarity)
AFULGI_00019340	ENOG41080XS	Cobyrinic acid ac-diamide synthase
AFULGI_00019410	ENOG4105CSM	endonuclease III
AFULGI_00019420	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
AFULGI_00019440	ENOG4108JZF	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
AFULGI_00019470	ENOG4108V1U	phospholipid-binding protein
AFULGI_00019500	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
AFULGI_00019510	ENOG4105DDK	oxidoreductase, beta subunit
AFULGI_00019530	ENOG4105E63	Pfam:DUF178
AFULGI_00019550	ENOG4108MXF	Alpha Beta Hydrolase
AFULGI_00019570	ENOG4105DZR	Type I site-specific deoxyribonuclease
AFULGI_00019600	ENOG4105EKX	Restriction modification system DNA (Specificity
AFULGI_00019650	ENOG4105CVR	type I restriction-modification system
AFULGI_00019710	ENOG4105C7K	acetolactate synthase
AFULGI_00019720	ENOG41062D9	Histidine kinase
AFULGI_00019770	ENOG4105FDF	Could be involved in DNA repair (By similarity)
AFULGI_00019780	ENOG4105C6K	Malic enzyme
AFULGI_00019790	ENOG4107R5M	Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway (By similarity)
AFULGI_00019810	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
AFULGI_00019880	ENOG4105C7Z	Conserved Protein
AFULGI_00019920	ENOG41065E1	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
AFULGI_00019950	ENOG4108VTU	Cdp-alcohol phosphatidyltransferase
AFULGI_00019980	ENOG4108YZA	Nitrogen regulatory protein pii
AFULGI_00019990	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AFULGI_00020000	ENOG4105BZU	Histidine kinase
AFULGI_00020020	ENOG4105E3H	phosphoglycerate mutase
AFULGI_00020030	ENOG4108JQ0	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
AFULGI_00020060	ENOG4108UMN	azlc family
AFULGI_00020120	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AFULGI_00020150	ENOG4108UK2	deaminase
AFULGI_00020160	ENOG4105EYA	deoxyribonuclease
AFULGI_00020180	ENOG4105DEF	Extracellular solute-binding protein, family 5
AFULGI_00020190	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
AFULGI_00020200	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
AFULGI_00020220	ENOG4108JQ7	(ABC) transporter
AFULGI_00020230	ENOG4105CEY	Amp-dependent synthetase and ligase
AFULGI_00020240	ENOG4105DF6	Fe-S oxidoreductase
AFULGI_00020250	ENOG4107RY6	amino acid
AFULGI_00020280	ENOG4107XF7	NGG1p interacting factor 3 protein, NIF3
AFULGI_00020290	ENOG4105K4W	Could be involved in septation (By similarity)
AFULGI_00020300	ENOG4105C5I	Dehydrogenase
AFULGI_00020310	ENOG4105C7K	acetolactate synthase
AFULGI_00020340	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
AFULGI_00020380	ENOG4105HSZ	Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis (By similarity)
AFULGI_00020390	ENOG4107RHB	Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates (By similarity)
AFULGI_00020460	ENOG4105CN9	Peptidase m42 family protein
AFULGI_00020480	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
AFULGI_00020530	ENOG4106FVC	RNA methyltransferase
AFULGI_00020610	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AFULGI_00020620	ENOG4105DC1	bifunctional purine biosynthesis protein purh
AFULGI_00020710	ENOG41067SE	Tetr family transcriptional regulator
AFULGI_00020730	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
AFULGI_00020790	ENOG4105D65	subunit l
AFULGI_00020800	ENOG4105D65	subunit l
AFULGI_00020810	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AFULGI_00020830	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
AFULGI_00020920	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AFULGI_00020930	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
AFULGI_00020950	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
AFULGI_00020960	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
AFULGI_00020970	ENOG4108JJB	ABC transporter
AFULGI_00020990	ENOG4105CFT	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import (By similarity)
AFULGI_00021030	ENOG4105CJG	carbon-monoxide dehydrogenase catalytic subunit
AFULGI_00021080	ENOG4105CYC	Transferase
AFULGI_00021090	ENOG4105CEY	Amp-dependent synthetase and ligase
AFULGI_00021130	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
AFULGI_00021420	ENOG4105CJ1	ABC, transporter
AFULGI_00021450	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AFULGI_00021460	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AFULGI_00021480	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
AFULGI_00021500	ENOG4105CHV	Transcription elongation factor NusA
AFULGI_00021530	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
AFULGI_00021550	ENOG4105CS1	NAD(P)H quinone oxidoreductase
AFULGI_00021570	ENOG4107YTP	response regulator receiver protein
AFULGI_00021580	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
AFULGI_00021610	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
AFULGI_00021620	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
AFULGI_00021640	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
AFULGI_00021650	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
AFULGI_00021680	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
AFULGI_00021690	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
AFULGI_00021710	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AFULGI_00021730	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
AFULGI_00021740	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
AFULGI_00021750	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
AFULGI_00021780	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
AFULGI_00021790	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
AFULGI_00021800	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
AFULGI_00021810	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AFULGI_00021820	ENOG41080UE	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
AFULGI_00021840	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
AFULGI_00021890	ENOG4105DCC	Formylmethanofuran dehydrogenase subunit A
AFULGI_00021910	ENOG4105CEY	Amp-dependent synthetase and ligase
AFULGI_00021950	ENOG41068T5	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT (By similarity)
AFULGI_00021960	ENOG4108T9Q	UPF0278 protein
AFULGI_00021980	ENOG4105CD5	CoA-binding domain protein
AFULGI_00022000	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
AFULGI_00022010	ENOG4105VR9	phosphoribosylformylglycinamidine synthase
AFULGI_00022090	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
AFULGI_00022100	ENOG4105CTP	PilT protein domain protein
AFULGI_00022130	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AFULGI_00022140	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
AFULGI_00022160	ENOG4105DCU	2-hydroxyglutaryl-CoA dehydratase
AFULGI_00022170	ENOG4105CMH	dehydratase
AFULGI_00022180	ENOG4105CIZ	coA-substrate-specific enzyme activase
AFULGI_00022190	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
AFULGI_00022230	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AFULGI_00022280	ENOG4105E2R	ROK family
AFULGI_00022290	ENOG4105NBF	ammecr1 domain protein
AFULGI_00022310	ENOG4105VN1	Heat shock protein
AFULGI_00022340	ENOG4105D52	delta-aminolevulinic acid dehydratase
AFULGI_00022350	ENOG4105C7E	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) (By similarity)
AFULGI_00022360	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AFULGI_00022410	ENOG41060IM	Heme exporter protein
AFULGI_00022420	ENOG4105FAV	ABC, transporter
AFULGI_00022450	ENOG4107XSR	periplasmic solute binding protein
AFULGI_00022470	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
AFULGI_00022540	ENOG4108YZY	peptidylprolyl cis-trans isomerase
AFULGI_00022600	ENOG4105C8J	)-transporter
AFULGI_00022620	ENOG4105DF6	Fe-S oxidoreductase
AFULGI_00022640	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
AFULGI_00022660	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AFULGI_00022680	ENOG4107SJ9	decarboxylase
AFULGI_00022690	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
AFULGI_00022700	ENOG4105CM1	Catalyzes, together with MoaC, the conversion of 5'-GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AFULGI_00022710	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
AFULGI_00022780	ENOG4105DZS	Phenylacetate-CoA ligase
AFULGI_00022800	ENOG4105C7K	acetolactate synthase
AFULGI_00022820	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AFULGI_00022840	ENOG4105C0A	alcohol dehydrogenase
AFULGI_00022890	ENOG4105CIH	Imidazole acetol-phosphate transaminase
AFULGI_00022990	ENOG4105CEY	Amp-dependent synthetase and ligase
AFULGI_00023000	ENOG4105DC7	peptidase M24
AFULGI_00023010	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
AFULGI_00023020	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
AFULGI_00023040	ENOG4105C35	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P) (By similarity)
AFULGI_00023050	ENOG4105F23	Fibronectin-binding protein
AFULGI_00023060	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
AFULGI_00023100	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
AFULGI_00023120	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
AFULGI_00023130	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
AFULGI_00023150	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
AFULGI_00023180	ENOG4108YXI	Secondary thiamine-phosphate synthase enzyme
AFULGI_00023190	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
AFULGI_00023200	ENOG4105DDK	oxidoreductase, beta subunit
AFULGI_00023210	ENOG4105D95	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (By similarity)
AFULGI_00023220	ENOG4105WGB	oxidoreductase, delta subunit
AFULGI_00023250	ENOG4105C1G	acyl-Coa dehydrogenase
AFULGI_00023300	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
AFULGI_00023420	ENOG4105FIE	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) (By similarity)
AFULGI_00023430	ENOG4108UV6	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity)
AFULGI_00023440	ENOG4105C4U	4-methyl-5-beta-hydroxyethylthiazole kinase
AFULGI_00023530	ENOG4105D9Q	decarboxylase (Beta subunit)
AFULGI_00023540	ENOG4107QSA	Oxaloacetate decarboxylase
AFULGI_00023580	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
AFULGI_00023650	ENOG4105C8M	UPF0272 protein
AFULGI_00023660	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
AFULGI_00023670	ENOG4105DIA	mandelate racemase muconate lactonizing
AFULGI_00023680	ENOG4105C7K	acetolactate synthase
AFULGI_00023690	ENOG4105CPQ	Dehydrogenase
AFULGI_00023770	ENOG4105CEQ	signal transduction histidine kinase regulating citrate malate metabolism
AFULGI_00023790	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
AFULGI_00023840	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AFULGI_00023970	ENOG410811B	TRANSCRIPTIONal
AFULGI_00023980	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
AFULGI_00023990	ENOG4105CHM	Aminotransferase
AFULGI_00024060	ENOG41082BM	Transcriptional regulator, arsr family
AFULGI_00024160	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AFULGI_00024180	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AFULGI_00024200	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
AFULGI_00024210	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
AFULGI_00024250	ENOG4105CY0	Metallo-Beta-Lactamase
AFULGI_00024270	ENOG4105M7V	2'-5' rna ligase
AFULGI_00024440	ENOG4105EA8	2-Nitropropane dioxygenase
AFULGI_00024480	ENOG4107QRT	dEAD DEAH box helicase
AFULGI_00024490	ENOG4105C4H	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA (By similarity)
AFULGI_00024500	ENOG4108ZAF	Molybdopterin
AFULGI_00024550	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AFULGI_00024560	ENOG4105CH8	Succinyl-CoA ligase ADP-forming subunit alpha
AFULGI_00024570	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
AFULGI_00024640	ENOG4105DA4	cytochrome c-type biogenesis protein
AFULGI_00024660	ENOG4105F59	Methylates ribosomal protein L11 (By similarity)
AFULGI_00024670	ENOG4105E0R	Deoxyhypusine synthase
AFULGI_00024680	ENOG4105I9Z	UPF0264 protein
AFULGI_00024710	ENOG4105CQI	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
AFULGI_00024720	ENOG4105PTV	Nudix Hydrolase
AFULGI_00024790	ENOG4105FIE	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) (By similarity)
AFULGI_00024800	ENOG4105DWF	phosphomethylpyrimidine kinase
AFULGI_00024910	ENOG4107QSA	Oxaloacetate decarboxylase
AFULGI_00024930	ENOG4107QX3	carboxylase
AFULGI_00024940	ENOG4108ZVT	methylmalonyl-coA epimerase
AFULGI_00024980	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
AFULGI_00025000	ENOG4105D8I	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS (By similarity)
AFULGI_00025220	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
AFULGI_00025250	ENOG4105N80	Ferric uptake regulator, Fur family
AFULGI_00025260	ENOG4105C1X	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity (By similarity)
AFULGI_00025300	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
AFULGI_00025310	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
AFULGI_00025350	ENOG4105C83	adenylosuccinate lyase
AFULGI_00025360	ENOG4105CHU	acetyl-coa acetyltransferase
AFULGI_00025370	ENOG4105C1G	acyl-Coa dehydrogenase
AFULGI_00025380	ENOG4105CQR	helicase
AFULGI_00025430	ENOG4107YTP	response regulator receiver protein
AFULGI_00025440	ENOG4105CD3	dihydroorotase
AFULGI_00025450	ENOG4105CEV	competence damage-inducible protein
AFULGI_00025460	ENOG4105CDH	Citrulline--aspartate ligase
AFULGI_00025470	ENOG4105FNP	Molybdopterin-guanine dinucleotide biosynthesis protein b
AFULGI_00025480	ENOG4105C1J	atp-dependent rna helicase
AFULGI_00025490	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
AFULGI_00025510	ENOG4105CPF	Cell wall formation (By similarity)
AFULGI_00025530	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
AFULGI_00025610	ENOG4107YAU	phenylacetic acid degradation protein
AFULGI_00025620	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
AFULGI_00025630	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
AFULGI_00025640	ENOG4108RCM	Nitroreductase
AFULGI_00025660	ENOG4105D1F	ATP-binding protein
AFULGI_00025700	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
AFULGI_00025750	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
AFULGI_00025790	ENOG4105WE2	aldehyde ferredoxin oxidoreductase
AFULGI_00025810	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
AFULGI_00025820	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
AFULGI_00025830	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AFULGI_00025840	ENOG4105EAH	synthase
AFULGI_00025850	ENOG4106UJV	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) (By similarity)
AFULGI_00025880	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
AFULGI_00025890	ENOG4105DGU	Histone deacetylase
AFULGI_00025980	ENOG4108Y5D	Inherit from COG: cdp-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase
AFULGI_00026000	ENOG4108JEJ	Pyruvoyl-dependent arginine decarboxylase
AFULGI_00026100	ENOG41074MP	UPF0103 Mediator of ErbB2-driven cell motility-containing protein
AFULGI_00026130	ENOG4105DXM	phenylacetic acid degradation protein
AFULGI_00026140	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
AFULGI_00026220	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
AFULGI_00026270	ENOG4105E2X	shikimate dehydrogenase
AFULGI_00026280	ENOG4105VB5	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
AFULGI_00026290	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
AFULGI_00026340	ENOG4105CCX	Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor (By similarity)
AFULGI_00026350	ENOG4105C22	threonyL-tRNA synthetase
AFULGI_00026360	ENOG4108EMS	branched-chain alpha-keto acid dehydrogenase subunit E2
AFULGI_00026430	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
AFULGI_00026450	ENOG4105DIW	FeS assembly protein SUFB
AFULGI_00026470	ENOG4105CHM	Aminotransferase
AFULGI_00026480	ENOG4108Z24	l-2,4-diaminobutyric acid acetyltransferase
AFULGI_00026490	ENOG4105CEY	Amp-dependent synthetase and ligase
AFULGI_00026550	ENOG4107TK4	histidinol-phosphate phosphatase
AFULGI_00026560	ENOG4105F91	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus (By similarity)
AFULGI_00026620	ENOG4105C2N	RNA methyltransferase TrmH family group 3
AFULGI_00026690	ENOG4108I5C	dEAD DEAH box helicase
AFULGI_00026700	ENOG4105C5X	domain protein
AFULGI_00026730	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
AFULGI_00026760	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
AFULGI_00026840	ENOG4108UXN	response regulator
AFULGI_00026850	ENOG4105BZU	Histidine kinase
AFULGI_00026860	ENOG4105C8T	Leucyl-tRNA synthetase
AFULGI_00026900	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
AFULGI_00026940	ENOG4105E39	Enoyl-CoA hydratase
AFULGI_00026960	ENOG4108JEJ	Pyruvoyl-dependent arginine decarboxylase
AFULGI_00026990	ENOG4105ZHF	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease (By similarity)
AFULGI_00027000	ENOG4105DYN	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. May be involved in the integration of spacer DNA into the CRISPR cassette (By similarity)