locus-tag	class	description
AFULGI_00000020	COG4604	ABC transporter, ATP-binding protein
AFULGI_00000040	COG5012	cobalamin binding
AFULGI_00000070	COG1962	PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit
AFULGI_00000090	COG5012	cobalamin binding
AFULGI_00000150	COG1250	3-hydroxyacyl-CoA dehydrogenase
AFULGI_00000160	COG0183	Belongs to the thiolase family
AFULGI_00000190	COG3290	protein histidine kinase activity
AFULGI_00000210	COG2414	aldehyde ferredoxin oxidoreductase
AFULGI_00000250	COG4274	PFAM GYD family protein
AFULGI_00000310	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AFULGI_00000320	COG0183	Belongs to the thiolase family
AFULGI_00000440	COG1812	S-adenosylmethionine synthetase (AdoMet synthetase)
AFULGI_00000450	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AFULGI_00000540	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AFULGI_00000550	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
AFULGI_00000670	COG1598	PFAM Uncharacterised protein family UPF0150
AFULGI_00000690	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
AFULGI_00000690	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
AFULGI_00000710	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
AFULGI_00000750	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AFULGI_00000820	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AFULGI_00000850	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AFULGI_00000850	COG1116	anion transmembrane transporter activity
AFULGI_00000870	COG0318	PFAM AMP-dependent synthetase and ligase
AFULGI_00000900	COG3842	ATPase activity
AFULGI_00000910	COG4149	molybdate abc transporter
AFULGI_00000920	COG0725	ABC transporter, periplasmic molybdate-binding protein
AFULGI_00001030	COG0540	Belongs to the ATCase OTCase family
AFULGI_00001040	COG1781	'de novo' pyrimidine nucleobase biosynthetic process
AFULGI_00001050	COG1830	Aldolase
AFULGI_00001070	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AFULGI_00001090	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AFULGI_00001120	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
AFULGI_00001380	COG2226	methyltransferase
AFULGI_00001520	COG0672	)-iron permease
AFULGI_00001550	COG0437	4 iron, 4 sulfur cluster binding
AFULGI_00001630	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AFULGI_00001650	COG1141	Ferredoxin
AFULGI_00001680	COG0822	iron-sulfur transferase activity
AFULGI_00001690	COG1104	cysteine desulfurase activity
AFULGI_00001710	COG0425	Belongs to the sulfur carrier protein TusA family
AFULGI_00001810	COG0318	PFAM AMP-dependent synthetase and ligase
AFULGI_00001820	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AFULGI_00001830	COG2030	dehydratase
AFULGI_00001830	COG1012	belongs to the aldehyde dehydrogenase family
AFULGI_00001850	COG1022	Amp-dependent synthetase and ligase
AFULGI_00001900	COG2264	protein methyltransferase activity
AFULGI_00001940	COG0642	Histidine kinase
AFULGI_00001950	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AFULGI_00001970	COG2239	Acts as a magnesium transporter
AFULGI_00001980	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AFULGI_00002020	COG2264	protein methyltransferase activity
AFULGI_00002030	COG0569	domain protein
AFULGI_00002030	COG0475	glutathione-regulated potassium exporter activity
AFULGI_00002050	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AFULGI_00002060	COG0439	Biotin carboxylase
AFULGI_00002070	COG0410	ABC transporter
AFULGI_00002080	COG0411	ABC transporter
AFULGI_00002100	COG0559	Belongs to the binding-protein-dependent transport system permease family
AFULGI_00002130	COG1605	Chorismate mutase
AFULGI_00002130	COG0077	Prephenate dehydratase
AFULGI_00002150	COG1465	3-dehydroquinate synthase
AFULGI_00002160	COG1830	Aldolase
AFULGI_00002170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AFULGI_00002190	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AFULGI_00002200	COG0501	Belongs to the peptidase M48B family
AFULGI_00002240	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
AFULGI_00002280	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AFULGI_00002320	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
AFULGI_00002320	COG1918	ferrous iron import across plasma membrane
AFULGI_00002380	COG2835	tetraacyldisaccharide 4'-kinase activity
AFULGI_00002390	COG0504	CTP synthase activity
AFULGI_00002400	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AFULGI_00002400	COG0519	Catalyzes the synthesis of GMP from XMP
AFULGI_00002410	COG0446	pyridine nucleotide-disulphide oxidoreductase
AFULGI_00002510	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AFULGI_00002530	COG0318	PFAM AMP-dependent synthetase and ligase
AFULGI_00002550	COG1213	nucleotidyl transferase
AFULGI_00002550	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AFULGI_00002630	COG0450	alkyl hydroperoxide reductase
AFULGI_00002690	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AFULGI_00002710	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AFULGI_00002730	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AFULGI_00002770	COG0183	Belongs to the thiolase family
AFULGI_00002790	COG1250	3-hydroxyacyl-CoA dehydrogenase
AFULGI_00002810	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
AFULGI_00002980	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AFULGI_00003190	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
AFULGI_00003200	COG1091	dTDP-4-dehydrorhamnose reductase activity
AFULGI_00003210	COG1088	dTDP-glucose 4,6-dehydratase activity
AFULGI_00003260	COG0438	transferase activity, transferring glycosyl groups
AFULGI_00003270	COG1216	Glycosyl transferase, family 2
AFULGI_00003380	COG1454	alcohol dehydrogenase
AFULGI_00003430	COG2033	superoxide reductase activity
AFULGI_00003450	COG2217	Heavy metal translocating P-type atpase
AFULGI_00003560	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AFULGI_00003570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
AFULGI_00003590	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AFULGI_00003650	COG0470	DNA polymerase III
AFULGI_00003650	COG1067	ATP-dependent peptidase activity
AFULGI_00003670	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AFULGI_00003680	COG2271	Major facilitator Superfamily
AFULGI_00003700	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AFULGI_00003710	COG1059	Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites)
AFULGI_00003720	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AFULGI_00003740	COG0647	UMP catabolic process
AFULGI_00003870	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AFULGI_00003890	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AFULGI_00003910	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AFULGI_00003940	COG1131	(ABC) transporter
AFULGI_00004040	COG0446	pyridine nucleotide-disulphide oxidoreductase
AFULGI_00004140	COG0436	Aminotransferase
AFULGI_00004150	COG4191	Histidine kinase
AFULGI_00004160	COG0215	cysteine-tRNA ligase activity
AFULGI_00004230	COG0434	BtpA family
AFULGI_00004260	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AFULGI_00004260	COG1648	precorrin-2 dehydrogenase activity
AFULGI_00004270	COG2221	Nitrite and sulphite reductase 4Fe-4S
AFULGI_00004280	COG2221	Nitrite and sulphite reductase 4Fe-4S
AFULGI_00004320	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AFULGI_00004350	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFULGI_00004370	COG1720	tRNA m6t6A37 methyltransferase activity
AFULGI_00004380	COG1250	3-hydroxyacyl-CoA dehydrogenase
AFULGI_00004390	COG1024	Enoyl-CoA hydratase
AFULGI_00004400	COG1960	acyl-CoA dehydrogenase activity
AFULGI_00004420	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AFULGI_00004440	COG0720	synthase
AFULGI_00004450	COG0602	queuosine metabolic process
AFULGI_00004460	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AFULGI_00004540	COG5002	protein histidine kinase activity
AFULGI_00004550	COG2201	protein-glutamate methylesterase activity
AFULGI_00004560	COG3290	protein histidine kinase activity
AFULGI_00004610	COG1902	pentaerythritol trinitrate reductase activity
AFULGI_00004610	COG0446	pyridine nucleotide-disulphide oxidoreductase
AFULGI_00004640	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AFULGI_00004650	COG2409	Drug exporters of the RND superfamily
AFULGI_00004720	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
AFULGI_00004760	COG1013	pyruvate-flavodoxin oxidoreductase activity
AFULGI_00004770	COG0674	pyruvate-flavodoxin oxidoreductase activity
AFULGI_00004770	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
AFULGI_00004810	COG2217	Heavy metal translocating P-type atpase
AFULGI_00004820	COG1522	sequence-specific DNA binding
AFULGI_00004830	COG0798	PFAM Bile acid sodium symporter
AFULGI_00004850	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AFULGI_00004860	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AFULGI_00004890	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
AFULGI_00004900	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AFULGI_00004920	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AFULGI_00004920	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
AFULGI_00005000	COG1185	polyribonucleotide nucleotidyltransferase activity
AFULGI_00005010	COG1185	polyribonucleotide nucleotidyltransferase activity
AFULGI_00005020	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AFULGI_00005060	COG0417	DNA replication proofreading
AFULGI_00005160	COG2181	nitrate reductase activity
AFULGI_00005160	COG0247	lactate metabolic process
AFULGI_00005180	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
AFULGI_00005190	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
AFULGI_00005220	COG2226	methyltransferase
AFULGI_00005310	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AFULGI_00005360	COG1185	polyribonucleotide nucleotidyltransferase activity
AFULGI_00005370	COG0543	2 iron, 2 sulfur cluster binding
AFULGI_00005390	COG0187	DNA topoisomerase II activity
AFULGI_00005400	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AFULGI_00005440	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AFULGI_00005470	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AFULGI_00005510	COG0731	radical SAM domain protein
AFULGI_00005510	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AFULGI_00005530	COG0247	lactate metabolic process
AFULGI_00005570	COG0247	lactate metabolic process
AFULGI_00005580	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AFULGI_00005600	COG0402	S-adenosylhomocysteine deaminase activity
AFULGI_00005610	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AFULGI_00005620	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AFULGI_00005630	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
AFULGI_00005660	COG0425	Belongs to the sulfur carrier protein TusA family
AFULGI_00005670	COG0446	pyridine nucleotide-disulphide oxidoreductase
AFULGI_00005690	COG0482	sulfurtransferase activity
AFULGI_00005780	COG1104	cysteine desulfurase activity
AFULGI_00005790	COG0822	iron-sulfur transferase activity
AFULGI_00005820	COG0318	PFAM AMP-dependent synthetase and ligase
AFULGI_00005870	COG1846	Transcriptional regulator
AFULGI_00005910	COG3118	belongs to the thioredoxin family
AFULGI_00005980	COG0175	sulfate reduction
AFULGI_00006030	COG4637	Psort location Cytoplasmic, score
AFULGI_00006040	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AFULGI_00006050	COG0758	DNA mediated transformation
AFULGI_00006080	COG0546	phosphoglycolate phosphatase activity
AFULGI_00006120	COG1401	restriction endodeoxyribonuclease activity
AFULGI_00006170	COG1196	nuclear chromosome segregation
AFULGI_00006180	COG0420	3'-5' exonuclease activity
AFULGI_00006230	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AFULGI_00006270	COG1353	crispr-associated protein
AFULGI_00006290	COG1337	RAMP superfamily
AFULGI_00006380	COG2002	toxin-antitoxin pair type II binding
AFULGI_00006460	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AFULGI_00006510	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AFULGI_00006560	COG0708	Exodeoxyribonuclease III
AFULGI_00006570	COG0463	Glycosyl transferase, family 2
AFULGI_00006630	COG0343	queuine tRNA-ribosyltransferase activity
AFULGI_00006640	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AFULGI_00006650	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AFULGI_00006670	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AFULGI_00006710	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
AFULGI_00006810	COG2226	methyltransferase
AFULGI_00006960	COG0297	glycogen (starch) synthase activity
AFULGI_00007010	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AFULGI_00007030	COG1793	dna ligase
AFULGI_00007080	COG0473	3-isopropylmalate dehydrogenase activity
AFULGI_00007090	COG0066	3-isopropylmalate dehydratase activity
AFULGI_00007130	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
AFULGI_00007140	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AFULGI_00007200	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AFULGI_00007210	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AFULGI_00007210	COG1116	anion transmembrane transporter activity
AFULGI_00007250	COG0010	Belongs to the arginase family
AFULGI_00007260	COG0538	isocitrate dehydrogenase activity
AFULGI_00007340	COG0446	pyridine nucleotide-disulphide oxidoreductase
AFULGI_00007400	COG1694	Mazg nucleotide pyrophosphohydrolase
AFULGI_00007420	COG0431	NADPH-dependent FMN reductase
AFULGI_00007420	COG1053	succinate dehydrogenase
AFULGI_00007420	COG3976	FMN-binding domain protein
AFULGI_00007430	COG1233	COG1233 Phytoene dehydrogenase and related
AFULGI_00007450	COG2815	serine threonine protein kinase
AFULGI_00007450	COG0515	serine threonine protein kinase
AFULGI_00007500	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AFULGI_00007510	COG1960	acyl-CoA dehydrogenase activity
AFULGI_00007520	COG0318	PFAM AMP-dependent synthetase and ligase
AFULGI_00007560	COG0563	adenylate kinase activity
AFULGI_00007570	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AFULGI_00007590	COG3335	DDE superfamily endonuclease
AFULGI_00007610	COG1053	succinate dehydrogenase
AFULGI_00007660	COG1024	Enoyl-CoA hydratase
AFULGI_00007680	COG0318	PFAM AMP-dependent synthetase and ligase
AFULGI_00007720	COG2871	sodium ion transport
AFULGI_00007780	COG2894	cell division
AFULGI_00007840	COG1635	Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur
AFULGI_00007890	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AFULGI_00007920	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AFULGI_00007920	COG0574	Belongs to the PEP-utilizing enzyme family
AFULGI_00007950	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AFULGI_00007990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AFULGI_00008080	COG0310	cobalt ion transport
AFULGI_00008110	COG1122	ATPase activity
AFULGI_00008130	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
AFULGI_00008180	COG2104	thiamine diphosphate biosynthetic process
AFULGI_00008220	COG0432	Pfam Uncharacterised protein family UPF0047
AFULGI_00008240	COG0864	Transcriptional regulator
AFULGI_00008260	COG0167	dihydroorotate dehydrogenase activity
AFULGI_00008280	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AFULGI_00008310	COG1013	pyruvate-flavodoxin oxidoreductase activity
AFULGI_00008360	COG0247	lactate metabolic process
AFULGI_00008360	COG2181	nitrate reductase activity
AFULGI_00008370	COG1227	inorganic diphosphatase activity
AFULGI_00008480	COG0105	UTP biosynthetic process
AFULGI_00008510	COG5002	protein histidine kinase activity
AFULGI_00008560	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AFULGI_00008610	COG0009	L-threonylcarbamoyladenylate synthase
AFULGI_00008640	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AFULGI_00008660	COG0598	Magnesium transport protein CorA
AFULGI_00008700	COG0697	spore germination
AFULGI_00008790	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AFULGI_00008800	COG1060	Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate
AFULGI_00008830	COG0019	diaminopimelate decarboxylase activity
AFULGI_00008910	COG1620	l-lactate permease
AFULGI_00008930	COG0277	FAD linked oxidase domain protein
AFULGI_00008970	COG1139	Iron-sulfur cluster binding protein
AFULGI_00008990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AFULGI_00009010	COG1867	N(2),N(2)-dimethylguanosine tRNA methyltransferase
AFULGI_00009040	COG1254	Belongs to the acylphosphatase family
AFULGI_00009050	COG0107	imidazoleglycerol-phosphate synthase activity
AFULGI_00009080	COG0410	ABC transporter
AFULGI_00009090	COG0411	ABC transporter
AFULGI_00009110	COG0559	Belongs to the binding-protein-dependent transport system permease family
AFULGI_00009160	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
AFULGI_00009160	COG1773	rubredoxin
AFULGI_00009170	COG1592	Rubrerythrin
AFULGI_00009190	COG2033	superoxide reductase activity
AFULGI_00009220	COG0569	domain protein
AFULGI_00009240	COG0318	PFAM AMP-dependent synthetase and ligase
AFULGI_00009250	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AFULGI_00009290	COG1960	acyl-CoA dehydrogenase activity
AFULGI_00009310	COG0517	IMP dehydrogenase activity
AFULGI_00009310	COG1125	glycine betaine transport
AFULGI_00009320	COG0517	IMP dehydrogenase activity
AFULGI_00009360	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AFULGI_00009390	COG0039	L-malate dehydrogenase activity
AFULGI_00009490	COG0596	Alpha beta hydrolase
AFULGI_00009530	COG0277	FAD linked oxidase domain protein
AFULGI_00009540	COG0393	Putative heavy-metal-binding
AFULGI_00009560	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AFULGI_00009580	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AFULGI_00009620	COG4085	toxin activity
AFULGI_00009620	COG1525	nuclease
AFULGI_00009620	COG0737	Belongs to the 5'-nucleotidase family
AFULGI_00009670	COG1773	rubredoxin
AFULGI_00009690	COG2205	protein histidine kinase activity
AFULGI_00009700	COG0252	asparaginase activity
AFULGI_00009750	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AFULGI_00009820	COG3290	protein histidine kinase activity
AFULGI_00009870	COG1986	Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions
AFULGI_00009900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AFULGI_00009930	COG2271	Major facilitator Superfamily
AFULGI_00009950	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AFULGI_00009960	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AFULGI_00010000	COG0023	Translation Initiation Factor
AFULGI_00010020	COG0423	glycine-tRNA ligase activity
AFULGI_00010060	COG0017	Asparaginyl-tRNA synthetase
AFULGI_00010170	COG0546	phosphoglycolate phosphatase activity
AFULGI_00010180	COG0284	orotidine-5'-phosphate decarboxylase activity
AFULGI_00010190	COG0303	'Molybdopterin
AFULGI_00010200	COG0303	'Molybdopterin
AFULGI_00010230	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AFULGI_00010250	COG0460	homoserine dehydrogenase
AFULGI_00010270	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AFULGI_00010280	COG0051	transcription antitermination factor activity, RNA binding
AFULGI_00010290	COG1234	tRNA 3'-trailer cleavage
AFULGI_00010320	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AFULGI_00010330	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AFULGI_00010390	COG0174	glutamine synthetase
AFULGI_00010400	COG0437	4 iron, 4 sulfur cluster binding
AFULGI_00010410	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AFULGI_00010420	COG0067	glutamate synthase
AFULGI_00010430	COG0069	glutamate synthase activity
AFULGI_00010430	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AFULGI_00010470	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AFULGI_00010490	COG1137	ATPase activity
AFULGI_00010530	COG1024	Enoyl-CoA hydratase
AFULGI_00010590	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AFULGI_00010620	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AFULGI_00010630	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AFULGI_00010640	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AFULGI_00010650	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AFULGI_00010660	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AFULGI_00010670	COG0004	ammonium transporteR
AFULGI_00010700	COG1174	glycine betaine transport
AFULGI_00010710	COG1125	glycine betaine transport
AFULGI_00010710	COG0517	IMP dehydrogenase activity
AFULGI_00010750	COG4555	ABC transporter
AFULGI_00010760	COG0131	Imidazoleglycerol-phosphate dehydratase
AFULGI_00010760	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AFULGI_00010770	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AFULGI_00010790	COG0410	ABC transporter
AFULGI_00010820	COG0559	Belongs to the binding-protein-dependent transport system permease family
AFULGI_00010880	COG1418	mRNA catabolic process
AFULGI_00010910	COG0402	S-adenosylhomocysteine deaminase activity
AFULGI_00010990	COG0842	Transport permease protein
AFULGI_00011000	COG1131	(ABC) transporter
AFULGI_00011020	COG3335	DDE superfamily endonuclease
AFULGI_00011050	COG1378	Sugar-specific transcriptional regulator TrmB
AFULGI_00011100	COG0129	dihydroxy-acid dehydratase activity
AFULGI_00011130	COG0577	efflux transmembrane transporter activity
AFULGI_00011140	COG1136	(ABC) transporter
AFULGI_00011170	COG1131	(ABC) transporter
AFULGI_00011190	COG0644	oxidoreductase
AFULGI_00011200	COG1110	DNA topoisomerase II activity
AFULGI_00011210	COG1250	3-hydroxyacyl-CoA dehydrogenase
AFULGI_00011220	COG1960	acyl-CoA dehydrogenase activity
AFULGI_00011240	COG0183	Belongs to the thiolase family
AFULGI_00011250	COG0318	PFAM AMP-dependent synthetase and ligase
AFULGI_00011260	COG0433	COG0433 Predicted ATPase
AFULGI_00011300	COG0840	transmembrane signaling receptor activity
AFULGI_00011300	COG3290	protein histidine kinase activity
AFULGI_00011340	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AFULGI_00011350	COG1776	CheC inhibitor of MCP methylation
AFULGI_00011360	COG0643	Histidine kinase
AFULGI_00011360	COG2198	Histidine kinase
AFULGI_00011370	COG2201	protein-glutamate methylesterase activity
AFULGI_00011380	COG2201	protein-glutamate methylesterase activity
AFULGI_00011400	COG0835	chemotaxis
AFULGI_00011620	COG2201	protein-glutamate methylesterase activity
AFULGI_00011630	COG1121	(ABC) transporter
AFULGI_00011680	COG4145	pantothenate transmembrane transporter activity
AFULGI_00011720	COG1598	PFAM Uncharacterised protein family UPF0150
AFULGI_00012090	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AFULGI_00012140	COG1185	polyribonucleotide nucleotidyltransferase activity
AFULGI_00012190	COG1250	3-hydroxyacyl-CoA dehydrogenase
AFULGI_00012260	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AFULGI_00012310	COG0148	phosphopyruvate hydratase activity
AFULGI_00012320	COG0052	Belongs to the universal ribosomal protein uS2 family
AFULGI_00012380	COG1131	(ABC) transporter
AFULGI_00012410	COG1213	nucleotidyl transferase
AFULGI_00012440	COG0427	acetyl-CoA hydrolase
AFULGI_00012450	COG0126	phosphoglycerate kinase activity
AFULGI_00012460	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AFULGI_00012470	COG1522	sequence-specific DNA binding
AFULGI_00012480	COG1201	RNA secondary structure unwinding
AFULGI_00012580	COG0151	Belongs to the GarS family
AFULGI_00012600	COG1269	ATP hydrolysis coupled proton transport
AFULGI_00012630	COG1527	subunit (C
AFULGI_00012650	COG1155	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit
AFULGI_00012660	COG1156	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit
AFULGI_00012670	COG1394	ATPase activity, coupled to movement of substances
AFULGI_00012680	COG1268	BioY protein
AFULGI_00012690	COG1129	ABC transporter
AFULGI_00012740	COG1960	acyl-CoA dehydrogenase activity
AFULGI_00012760	COG1250	3-hydroxyacyl-CoA dehydrogenase
AFULGI_00012840	COG4191	Histidine kinase
AFULGI_00012860	COG0517	IMP dehydrogenase activity
AFULGI_00012860	COG0516	GMP reductase activity
AFULGI_00012870	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
AFULGI_00012890	COG1250	3-hydroxyacyl-CoA dehydrogenase
AFULGI_00012900	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
AFULGI_00012910	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AFULGI_00012910	COG0045	succinate-CoA ligase (ADP-forming) activity
AFULGI_00012910	COG1042	CoA-binding domain protein
AFULGI_00012940	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
AFULGI_00012950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AFULGI_00012960	COG0183	Belongs to the thiolase family
AFULGI_00012970	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
AFULGI_00012980	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
AFULGI_00013010	COG0437	4 iron, 4 sulfur cluster binding
AFULGI_00013050	COG1250	3-hydroxyacyl-CoA dehydrogenase
AFULGI_00013060	COG1028	Short-chain dehydrogenase reductase Sdr
AFULGI_00013090	COG3246	L-lysine catabolic process to acetate
AFULGI_00013100	COG0045	succinate-CoA ligase (ADP-forming) activity
AFULGI_00013100	COG1042	CoA-binding domain protein
AFULGI_00013100	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
AFULGI_00013110	COG0857	belongs to the CobB CobQ family
AFULGI_00013140	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
AFULGI_00013150	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
AFULGI_00013180	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AFULGI_00013230	COG1418	mRNA catabolic process
AFULGI_00013280	COG2409	Drug exporters of the RND superfamily
AFULGI_00013300	COG1378	Sugar-specific transcriptional regulator TrmB
AFULGI_00013380	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
AFULGI_00013390	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AFULGI_00013400	COG0181	hydroxymethylbilane synthase activity
AFULGI_00013410	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AFULGI_00013430	COG0475	glutathione-regulated potassium exporter activity
AFULGI_00013450	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AFULGI_00013460	COG1811	Na channel or pump
AFULGI_00013530	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AFULGI_00013540	COG2201	protein-glutamate methylesterase activity
AFULGI_00013550	COG0116	Belongs to the methyltransferase superfamily
AFULGI_00013570	COG0517	IMP dehydrogenase activity
AFULGI_00013570	COG1125	glycine betaine transport
AFULGI_00013580	COG0047	phosphoribosylformylglycinamidine synthase activity
AFULGI_00013610	COG1902	pentaerythritol trinitrate reductase activity
AFULGI_00013610	COG0446	pyridine nucleotide-disulphide oxidoreductase
AFULGI_00013640	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
AFULGI_00013700	COG0525	valine-tRNA ligase activity
AFULGI_00013740	COG1429	ligase activity, forming nitrogen-metal bonds
AFULGI_00013770	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
AFULGI_00013790	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AFULGI_00013800	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AFULGI_00013810	COG0505	Belongs to the CarA family
AFULGI_00013820	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AFULGI_00013830	COG1691	(AIR) carboxylase
AFULGI_00013850	COG0505	Belongs to the CarA family
AFULGI_00013880	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AFULGI_00013900	COG0693	protein deglycase activity
AFULGI_00013940	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AFULGI_00013960	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AFULGI_00014010	COG0183	Belongs to the thiolase family
AFULGI_00014030	COG1960	acyl-CoA dehydrogenase activity
AFULGI_00014080	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AFULGI_00014120	COG1131	(ABC) transporter
AFULGI_00014150	COG0149	triose-phosphate isomerase activity
AFULGI_00014160	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
AFULGI_00014190	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
AFULGI_00014200	COG0170	dolichyl monophosphate biosynthetic process
AFULGI_00014210	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AFULGI_00014250	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AFULGI_00014260	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AFULGI_00014310	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AFULGI_00014310	COG0519	Catalyzes the synthesis of GMP from XMP
AFULGI_00014320	COG0037	tRNA processing
AFULGI_00014370	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AFULGI_00014390	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AFULGI_00014470	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
AFULGI_00014500	COG1492	cobalamin metabolic process
AFULGI_00014510	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
AFULGI_00014520	COG0372	Belongs to the citrate synthase family
AFULGI_00014550	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AFULGI_00014560	COG0805	protein transport
AFULGI_00014600	COG1773	rubredoxin
AFULGI_00014610	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AFULGI_00014630	COG3335	DDE superfamily endonuclease
AFULGI_00014650	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AFULGI_00014650	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AFULGI_00014680	COG0573	inorganic phosphate transmembrane transporter activity
AFULGI_00014690	COG0581	inorganic phosphate transmembrane transporter activity
AFULGI_00014700	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AFULGI_00014750	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AFULGI_00014780	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AFULGI_00014790	COG0375	protein maturation
AFULGI_00014820	COG0409	Hydrogenase expression formation protein
AFULGI_00014840	COG3259	Nickel-dependent hydrogenase
AFULGI_00014850	COG1941	NADH ubiquinone oxidoreductase 20 kDa subunit
AFULGI_00014930	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AFULGI_00014960	COG2201	protein-glutamate methylesterase activity
AFULGI_00014980	COG2002	toxin-antitoxin pair type II binding
AFULGI_00015080	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
AFULGI_00015090	COG1657	PFAM Prenyltransferase squalene oxidase
AFULGI_00015130	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AFULGI_00015140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AFULGI_00015210	COG2189	Belongs to the N(4) N(6)-methyltransferase family
AFULGI_00015310	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
AFULGI_00015340	COG0330	HflC and HflK could
AFULGI_00015350	COG1615	UPF0182 protein
AFULGI_00015360	COG1794	racemase activity, acting on amino acids and derivatives
AFULGI_00015370	COG1078	dGTPase activity
AFULGI_00015390	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
AFULGI_00015400	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
AFULGI_00015470	COG1628	Protein of unknown function DUF99
AFULGI_00015490	COG0430	RNA-3'-phosphate cyclase activity
AFULGI_00015540	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AFULGI_00015560	COG1980	fructose-bisphosphate aldolase activity
AFULGI_00015570	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AFULGI_00015620	COG1522	sequence-specific DNA binding
AFULGI_00015670	COG5002	protein histidine kinase activity
AFULGI_00015680	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AFULGI_00015680	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AFULGI_00015950	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AFULGI_00016160	COG1598	PFAM Uncharacterised protein family UPF0150
AFULGI_00016890	COG1196	nuclear chromosome segregation
AFULGI_00016900	COG0420	3'-5' exonuclease activity
AFULGI_00017210	COG1136	(ABC) transporter
AFULGI_00017220	COG0577	efflux transmembrane transporter activity
AFULGI_00017220	COG1136	(ABC) transporter
AFULGI_00017250	COG0784	Response regulator, receiver
AFULGI_00017270	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
AFULGI_00017280	COG0346	lactoylglutathione lyase activity
AFULGI_00017350	COG0467	Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction
AFULGI_00017360	COG0343	queuine tRNA-ribosyltransferase activity
AFULGI_00017370	COG1892	Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle
AFULGI_00017400	COG1051	belongs to the nudix hydrolase family
AFULGI_00017400	COG1056	cytidyltransferase-related domain
AFULGI_00017420	COG0081	regulation of translation
AFULGI_00017430	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AFULGI_00017620	COG0318	PFAM AMP-dependent synthetase and ligase
AFULGI_00017640	COG0805	protein transport
AFULGI_00017690	COG1489	DNA binding
AFULGI_00017730	COG0426	domain, Protein
AFULGI_00017760	COG1444	tRNA N-acetyltransferase activity
AFULGI_00017910	COG2267	carboxylic ester hydrolase activity
AFULGI_00017920	COG2031	fatty acid transporter
AFULGI_00017930	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AFULGI_00017960	COG1695	Transcriptional regulator
AFULGI_00018000	COG0668	transmembrane transport
AFULGI_00018050	COG0142	geranyltranstransferase activity
AFULGI_00018070	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
AFULGI_00018080	COG0492	ferredoxin-NADP+ reductase activity
AFULGI_00018090	COG0482	sulfurtransferase activity
AFULGI_00018110	COG1196	nuclear chromosome segregation
AFULGI_00018320	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AFULGI_00018380	COG1850	ribulose-bisphosphate carboxylase activity
AFULGI_00018440	COG0037	tRNA processing
AFULGI_00018500	COG0133	tryptophan synthase activity
AFULGI_00018510	COG0135	phosphoribosylanthranilate isomerase activity
AFULGI_00018520	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AFULGI_00018520	COG0512	Glutamine amidotransferase of anthranilate synthase
AFULGI_00018530	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
AFULGI_00018540	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AFULGI_00018550	COG0134	indole-3-glycerol-phosphate synthase activity
AFULGI_00018570	COG1177	transmembrane transport
AFULGI_00018580	COG1176	ABC-type spermidine putrescine transport system, permease component I
AFULGI_00018590	COG3842	ATPase activity
AFULGI_00018610	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AFULGI_00018630	COG1113	amino acid transport
AFULGI_00018660	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AFULGI_00018690	COG2855	membrane
AFULGI_00018720	COG2855	membrane
AFULGI_00018740	COG0436	Aminotransferase
AFULGI_00018750	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AFULGI_00018810	COG1945	arginine decarboxylase activity
AFULGI_00018850	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AFULGI_00018880	COG1850	ribulose-bisphosphate carboxylase activity
AFULGI_00018890	COG5002	protein histidine kinase activity
AFULGI_00018900	COG1592	Rubrerythrin
AFULGI_00018910	COG1024	Enoyl-CoA hydratase
AFULGI_00018920	COG0124	histidyl-tRNA synthetase
AFULGI_00018930	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AFULGI_00018950	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AFULGI_00019020	COG1404	Belongs to the peptidase S8 family
AFULGI_00019020	COG1404	Belongs to the peptidase S8 family
AFULGI_00019200	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AFULGI_00019230	COG0371	Dehydrogenase
AFULGI_00019250	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AFULGI_00019260	COG0585	pseudouridine synthase activity
AFULGI_00019410	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AFULGI_00019420	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
AFULGI_00019440	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
AFULGI_00019470	COG1881	PFAM PEBP family protein
AFULGI_00019500	COG0674	pyruvate-flavodoxin oxidoreductase activity
AFULGI_00019510	COG1013	pyruvate-flavodoxin oxidoreductase activity
AFULGI_00019530	COG2107	Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2)
AFULGI_00019550	COG2267	carboxylic ester hydrolase activity
AFULGI_00019570	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AFULGI_00019600	COG0732	type I restriction modification DNA specificity domain
AFULGI_00019650	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AFULGI_00019680	COG2427	Protein of unknown function (DUF1641)
AFULGI_00019700	COG0440	acetolactate synthase activity
AFULGI_00019710	COG0028	Belongs to the TPP enzyme family
AFULGI_00019770	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
AFULGI_00019780	COG0281	malic enzyme
AFULGI_00019790	COG0297	glycogen (starch) synthase activity
AFULGI_00019810	COG0101	tRNA pseudouridine synthase activity
AFULGI_00019880	COG1331	Highly conserved protein containing a thioredoxin domain
AFULGI_00019920	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
AFULGI_00019950	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AFULGI_00019970	COG0004	ammonium transporteR
AFULGI_00019980	COG0347	Belongs to the P(II) protein family
AFULGI_00019990	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AFULGI_00020000	COG0004	ammonium transporteR
AFULGI_00020020	COG3635	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity
AFULGI_00020030	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
AFULGI_00020060	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
AFULGI_00020120	COG0066	3-isopropylmalate dehydratase activity
AFULGI_00020150	COG2131	deaminase
AFULGI_00020160	COG0084	hydrolase, TatD family'
AFULGI_00020180	COG0747	negative chemotaxis
AFULGI_00020190	COG0601	transmembrane transport
AFULGI_00020210	COG0444	Belongs to the ABC transporter superfamily
AFULGI_00020220	COG4608	Belongs to the ABC transporter superfamily
AFULGI_00020230	COG0318	PFAM AMP-dependent synthetase and ligase
AFULGI_00020240	COG0247	lactate metabolic process
AFULGI_00020240	COG2181	nitrate reductase activity
AFULGI_00020250	COG0531	amino acid
AFULGI_00020280	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
AFULGI_00020290	COG2088	sporulation resulting in formation of a cellular spore
AFULGI_00020300	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
AFULGI_00020310	COG0028	Belongs to the TPP enzyme family
AFULGI_00020340	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AFULGI_00020380	COG1426	Protein conserved in bacteria
AFULGI_00020390	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
AFULGI_00020460	COG1363	Peptidase, m42
AFULGI_00020530	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
AFULGI_00020610	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AFULGI_00020620	COG0138	bifunctional purine biosynthesis protein purh
AFULGI_00020660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AFULGI_00020710	COG1309	transcriptional regulator
AFULGI_00020730	COG1136	(ABC) transporter
AFULGI_00020790	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AFULGI_00020800	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
AFULGI_00020810	COG1007	ATP synthesis coupled electron transport
AFULGI_00020830	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AFULGI_00020920	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AFULGI_00020930	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AFULGI_00020950	COG0157	Belongs to the NadC ModD family
AFULGI_00020960	COG0024	Methionine aminopeptidase
AFULGI_00020970	COG1122	ATPase activity
AFULGI_00020990	COG0310	cobalt ion transport
AFULGI_00021030	COG1151	hydroxylamine reductase activity
AFULGI_00021080	COG0427	acetyl-CoA hydrolase
AFULGI_00021090	COG0318	PFAM AMP-dependent synthetase and ligase
AFULGI_00021130	COG0446	pyridine nucleotide-disulphide oxidoreductase
AFULGI_00021360	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AFULGI_00021420	COG1131	(ABC) transporter
AFULGI_00021450	COG0085	RNA polymerase activity
AFULGI_00021500	COG0195	Participates in both transcription termination and antitermination
AFULGI_00021530	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AFULGI_00021550	COG0655	NAD(P)H dehydrogenase (quinone) activity
AFULGI_00021570	COG2201	protein-glutamate methylesterase activity
AFULGI_00021580	COG0358	DNA primase activity
AFULGI_00021620	COG0200	Binds to the 23S rRNA
AFULGI_00021640	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
AFULGI_00021650	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AFULGI_00021680	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AFULGI_00021690	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
AFULGI_00021710	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AFULGI_00021730	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AFULGI_00021740	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AFULGI_00021750	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AFULGI_00021780	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AFULGI_00021790	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
AFULGI_00021800	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AFULGI_00021810	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AFULGI_00021820	COG0089	rRNA binding
AFULGI_00021840	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AFULGI_00021890	COG1229	Formylmethanofuran dehydrogenase subunit A
AFULGI_00021910	COG0318	PFAM AMP-dependent synthetase and ligase
AFULGI_00021950	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
AFULGI_00022000	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFULGI_00022010	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFULGI_00022090	COG0140	phosphoribosyl-ATP diphosphatase activity
AFULGI_00022090	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AFULGI_00022100	COG4956	integral membrane protein (PIN domain superfamily)
AFULGI_00022130	COG0154	amidase activity
AFULGI_00022140	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AFULGI_00022180	COG1924	4 iron, 4 sulfur cluster binding
AFULGI_00022190	COG0194	GDP metabolic process
AFULGI_00022230	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AFULGI_00022280	COG1940	carbohydrate kinase activity
AFULGI_00022290	COG2078	PFAM AMMECR1 domain protein
AFULGI_00022310	COG0071	Belongs to the small heat shock protein (HSP20) family
AFULGI_00022330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AFULGI_00022340	COG0113	porphobilinogen synthase activity
AFULGI_00022350	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AFULGI_00022360	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AFULGI_00022410	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AFULGI_00022420	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AFULGI_00022450	COG0803	Belongs to the bacterial solute-binding protein 9 family
AFULGI_00022470	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AFULGI_00022540	COG1047	Peptidyl-prolyl cis-trans
AFULGI_00022600	COG0733	neurotransmitter:sodium symporter activity
AFULGI_00022620	COG2181	nitrate reductase activity
AFULGI_00022620	COG0247	lactate metabolic process
AFULGI_00022640	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AFULGI_00022660	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AFULGI_00022690	COG0746	molybdenum cofactor guanylyltransferase activity
AFULGI_00022700	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AFULGI_00022710	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AFULGI_00022710	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AFULGI_00022780	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
AFULGI_00022800	COG0028	Belongs to the TPP enzyme family
AFULGI_00022820	COG1250	3-hydroxyacyl-CoA dehydrogenase
AFULGI_00022820	COG1024	Enoyl-CoA hydratase
AFULGI_00022840	COG1454	alcohol dehydrogenase
AFULGI_00022990	COG0318	PFAM AMP-dependent synthetase and ligase
AFULGI_00023000	COG0006	proline dipeptidase activity
AFULGI_00023010	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AFULGI_00023020	COG0109	protoheme IX farnesyltransferase activity
AFULGI_00023040	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AFULGI_00023100	COG0528	UMP kinase activity
AFULGI_00023120	COG1183	phosphatidylcholine synthase activity
AFULGI_00023130	COG0688	phosphatidylethanolamine metabolic process
AFULGI_00023150	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AFULGI_00023180	COG0432	Pfam Uncharacterised protein family UPF0047
AFULGI_00023190	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AFULGI_00023200	COG1013	pyruvate-flavodoxin oxidoreductase activity
AFULGI_00023210	COG0674	pyruvate-flavodoxin oxidoreductase activity
AFULGI_00023220	COG1144	Oxidoreductase
AFULGI_00023240	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AFULGI_00023250	COG1960	acyl-CoA dehydrogenase activity
AFULGI_00023300	COG0552	protein localization to endoplasmic reticulum
AFULGI_00023420	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
AFULGI_00023430	COG0352	thiamine-phosphate diphosphorylase activity
AFULGI_00023440	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AFULGI_00023530	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
AFULGI_00023540	COG0511	ligase activity, forming carbon-carbon bonds
AFULGI_00023540	COG5016	pyruvate
AFULGI_00023580	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AFULGI_00023660	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
AFULGI_00023680	COG0028	Belongs to the TPP enzyme family
AFULGI_00023770	COG3290	protein histidine kinase activity
AFULGI_00023790	COG2095	MarC family integral membrane protein
AFULGI_00023840	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AFULGI_00023970	COG0583	DNA-binding transcription factor activity
AFULGI_00023980	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AFULGI_00023990	COG0436	Aminotransferase
AFULGI_00024060	COG0640	Transcriptional regulator
AFULGI_00024070	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AFULGI_00024090	COG3335	DDE superfamily endonuclease
AFULGI_00024160	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
AFULGI_00024180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AFULGI_00024200	COG0315	cyclic pyranopterin monophosphate synthase activity
AFULGI_00024210	COG1335	isochorismatase
AFULGI_00024250	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
AFULGI_00024270	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
AFULGI_00024480	COG1201	RNA secondary structure unwinding
AFULGI_00024490	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AFULGI_00024490	COG0116	Belongs to the methyltransferase superfamily
AFULGI_00024500	COG0314	molybdopterin synthase activity
AFULGI_00024550	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AFULGI_00024560	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AFULGI_00024570	COG0045	succinate-CoA ligase (ADP-forming) activity
AFULGI_00024640	COG1138	Cytochrome C-type biogenesis protein
AFULGI_00024660	COG2264	protein methyltransferase activity
AFULGI_00024670	COG1899	peptidyl-lysine modification to peptidyl-hypusine
AFULGI_00024680	COG1891	lyase activity
AFULGI_00024710	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AFULGI_00024720	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
AFULGI_00024790	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
AFULGI_00024800	COG0351	phosphomethylpyrimidine kinase
AFULGI_00024800	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
AFULGI_00024800	COG0352	thiamine-phosphate diphosphorylase activity
AFULGI_00024910	COG5016	pyruvate
AFULGI_00024910	COG0511	ligase activity, forming carbon-carbon bonds
AFULGI_00024940	COG0346	lactoylglutathione lyase activity
AFULGI_00024980	COG0525	valine-tRNA ligase activity
AFULGI_00025000	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AFULGI_00025000	COG0301	tRNA thio-modification
AFULGI_00025220	COG1797	cobyrinic acid a,c-diamide synthase activity
AFULGI_00025250	COG0735	belongs to the Fur family
AFULGI_00025260	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AFULGI_00025300	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AFULGI_00025350	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
AFULGI_00025360	COG0183	Belongs to the thiolase family
AFULGI_00025370	COG1960	acyl-CoA dehydrogenase activity
AFULGI_00025380	COG4581	dead DEAH box helicase
AFULGI_00025430	COG2201	protein-glutamate methylesterase activity
AFULGI_00025450	COG1058	Belongs to the CinA family
AFULGI_00025450	COG1546	Belongs to the CinA family
AFULGI_00025460	COG0137	argininosuccinate synthase activity
AFULGI_00025470	COG1763	Mo-molybdopterin cofactor biosynthetic process
AFULGI_00025480	COG0513	Belongs to the DEAD box helicase family
AFULGI_00025490	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AFULGI_00025500	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
AFULGI_00025500	COG0778	Nitroreductase
AFULGI_00025510	COG1181	Belongs to the D-alanine--D-alanine ligase family
AFULGI_00025530	COG2814	Major facilitator Superfamily
AFULGI_00025610	COG2050	protein possibly involved in aromatic compounds catabolism
AFULGI_00025620	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AFULGI_00025630	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AFULGI_00025640	COG0778	Nitroreductase
AFULGI_00025660	COG0489	protein tyrosine kinase activity
AFULGI_00025700	COG1250	3-hydroxyacyl-CoA dehydrogenase
AFULGI_00025750	COG1573	uracil-dna glycosylase
AFULGI_00025790	COG2414	aldehyde ferredoxin oxidoreductase
AFULGI_00025810	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AFULGI_00025820	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AFULGI_00025830	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AFULGI_00025840	COG0142	geranyltranstransferase activity
AFULGI_00025880	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
AFULGI_00025890	COG0123	including yeast histone deacetylase and acetoin utilization protein
AFULGI_00025980	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
AFULGI_00025980	COG1213	nucleotidyl transferase
AFULGI_00026000	COG1945	arginine decarboxylase activity
AFULGI_00026020	COG0189	ligase activity
AFULGI_00026100	COG1355	regulation of microtubule-based process
AFULGI_00026130	COG2030	dehydratase
AFULGI_00026130	COG1012	belongs to the aldehyde dehydrogenase family
AFULGI_00026140	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AFULGI_00026150	COG1056	cytidyltransferase-related domain
AFULGI_00026150	COG1051	belongs to the nudix hydrolase family
AFULGI_00026160	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AFULGI_00026220	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AFULGI_00026270	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AFULGI_00026280	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AFULGI_00026290	COG0154	amidase activity
AFULGI_00026340	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AFULGI_00026350	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AFULGI_00026430	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AFULGI_00026450	COG0719	Fe-S assembly protein
AFULGI_00026470	COG0436	Aminotransferase
AFULGI_00026480	COG0456	acetyltransferase
AFULGI_00026490	COG0318	PFAM AMP-dependent synthetase and ligase
AFULGI_00026550	COG0483	inositol monophosphate 1-phosphatase activity
AFULGI_00026560	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AFULGI_00026620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AFULGI_00026690	COG1205	dead DEAH box helicase
AFULGI_00026690	COG1111	helicase
AFULGI_00026700	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AFULGI_00026730	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
AFULGI_00026760	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AFULGI_00026840	COG0784	Response regulator, receiver
AFULGI_00026850	COG5002	protein histidine kinase activity
AFULGI_00026860	COG0495	leucyl-tRNA aminoacylation
AFULGI_00026900	COG0714	Associated with various cellular activities
AFULGI_00026940	COG1024	Enoyl-CoA hydratase
AFULGI_00026960	COG1945	arginine decarboxylase activity
AFULGI_00026990	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
AFULGI_00027000	COG1518	maintenance of DNA repeat elements